diff options
| -rw-r--r-- | Dockerfile | 4 | ||||
| -rw-r--r-- | Makefile | 40 | ||||
| -rw-r--r-- | data/GENOTOX_data_and_dictionary.csv | 1084 | ||||
| -rw-r--r-- | data/GENOTOX_data_and_dictionary.tsv | 17928 | ||||
| -rw-r--r-- | data/efsa.csv | 798 | ||||
| -rw-r--r-- | data/kazius.csv | 4338 | ||||
| -rw-r--r-- | data/merged.csv | 8301 | ||||
| -rwxr-xr-x | scripts/efsa2csv.rb | 5 | ||||
| -rwxr-xr-x | scripts/kazius2csv.rb | 42 | ||||
| -rw-r--r-- | scripts/repeated_crossvalidation.rb | 10 |
10 files changed, 31900 insertions, 650 deletions
@@ -18,7 +18,9 @@ RUN pacman -S --noconfirm \ r \ ruby \ swig \ - vim \ + neovim \ + catdoc \ + fish \ wget RUN pacman -Scc --noconfirm @@ -1,11 +1,51 @@ +# TODO +# efsa smiles errors (encodings?) +# efsa script via csv +# remove headers from csv files +# add header at merged csv + +data = data/kazius.csv data/efsa.csv data/hansen.csv + +#all: $(data) +# experiments + +experiments/weighted_majority_merged.id: data/merged.csv + scripts/repeated_crossvalidation.rb data/merged.csv > $@ + +# training data + +data/merged.csv: $(data) + echo "SMILES,Activity" > $@ && cat $(data) | sort -u | sed '/SMILES/d' >> $@ + +# kazius + +data/kazius.csv: data/cas_4337.sdf + scripts/kazius2csv.rb $< > $@ + +data/cas_4337.sdf: data/cas_4337.zip + cd data && unzip cas_4337.zip + +data/cas_4337.zip: + cd data && wget "http://cheminformatics.org/datasets/bursi/cas_4337.zip" + +# efsa + data/efsa.csv: data/GENOTOX_data_and_dictionary.csv scripts/efsa2csv.rb $< > $@ data/GENOTOX_data_and_dictionary.csv: data/GENOTOX_data_and_dictionary.xls xls2csv $< > $@ +data/GENOTOX_data_and_dictionary.xls: + cd data && wget "https://data.europa.eu/euodp/data/storage/f/2017-07-19T142131/GENOTOX%20data%20and%20dictionary.xls" -o $@ + +# hansen + data/hansen.csv: data/Mutagenicity_N6512.csv scripts/hansen2csv.rb $< > $@ +data/Mutagenicity_N6512.csv: + cd data && wget "http://doc.ml.tu-berlin.de/toxbenchmark/Mutagenicity_N6512.csv" + clean: rm data/hansen.csv diff --git a/data/GENOTOX_data_and_dictionary.csv b/data/GENOTOX_data_and_dictionary.csv index 067e05a..ef17b51 100644 --- a/data/GENOTOX_data_and_dictionary.csv +++ b/data/GENOTOX_data_and_dictionary.csv @@ -124,21 +124,21 @@ "8-Hydroxyquinoline","205-711-1","148-24-3","single chemical entity","Component is identical to the substance","8-Hydroxyquinoline","205-711-1","148-24-3","Quinolin-8-ol","Not in list","C9H7NO","C1=CC2=C(C(=C1)O)N=CC=C2","InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","unscheduled DNA synthesis","in vivo","Equivalent or similar to","OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)","Yes","Acceptable","Rat (as animal)","Wistar","6","Male","oral: gavage","12","h","yes, concurrent vehicle","not applicable","Negative","","","RMS: Spain","8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline","40571","2011","doi:10.2903/j.efsa.2011.1964" "8-Hydroxyquinoline","205-711-1","148-24-3","single chemical entity","Component is identical to the substance","8-Hydroxyquinoline","205-711-1","148-24-3","Quinolin-8-ol","Not in list","C9H7NO","C1=CC2=C(C(=C1)O)N=CC=C2","InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","unscheduled DNA synthesis","in vivo","Equivalent or similar to","OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)","Yes","Acceptable","Rat (as animal)","Wistar","6","Male","oral: gavage","24","h","yes, concurrent vehicle","not applicable","Negative","","","RMS: Spain","8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline","40571","2011","doi:10.2903/j.efsa.2011.1964" "8-Hydroxyquinoline","205-711-1","148-24-3","single chemical entity","Component is identical to the substance","8-Hydroxyquinoline","205-711-1","148-24-3","Quinolin-8-ol","Not in list","C9H7NO","C1=CC2=C(C(=C1)O)N=CC=C2","InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","mammalian germ cell cytogenetic assay","in vivo","Equivalent or similar to","OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test)","Yes","Acceptable","House mouse (as animal)","NMRI","7","Male","oral: gavage","24","h","yes, concurrent vehicle","not applicable","Negative","","","RMS: Spain","8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline","40571","2011","doi:10.2903/j.efsa.2011.1964" -"Abamectin","","71751-41-2","mixture or formulation","Component is part of a mixture or forumlation","Avermectin B1a","265-610-3","65195-55-3","(2aZ,4Z,5?S,6S,6?R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6?-[(2S)-butan-2-yl]-20,20b-dihydroxy-5?,6,8,19-tetramethyl-17-oxo-5?,6,6?,10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2?-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Abamectin (Avermectin B1a)","C48H72O14","CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C","InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1","organic","compound","PubChem isomeric SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","mixture or formulation","Component is part of a mixture or forumlation","Avermectin B1a","265-610-3","65195-55-3","(2aZ,4Z,5?S,6S,6?R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6?-[(2S)-butan-2-yl]-20,20b-dihydroxy-5?,6,8,19-tetramethyl-17-oxo-5?,6,6?,10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2?-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Abamectin (Avermectin B1a)","C48H72O14","CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C","InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1","organic","compound","PubChem isomeric SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","mixture or formulation","Component is part of a mixture or forumlation","Avermectin B1a","265-610-3","65195-55-3","(2aZ,4Z,5?S,6S,6?R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6?-[(2S)-butan-2-yl]-20,20b-dihydroxy-5?,6,8,19-tetramethyl-17-oxo-5?,6,6?,10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2?-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Abamectin (Avermectin B1a)","C48H72O14","CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C","InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1","organic","compound","PubChem isomeric SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1538","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","mixture or formulation","Component is part of a mixture or forumlation","Avermectin B1a","265-610-3","65195-55-3","(2aZ,4Z,5?S,6S,6?R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6?-[(2S)-butan-2-yl]-20,20b-dihydroxy-5?,6,8,19-tetramethyl-17-oxo-5?,6,6?,10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2?-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Abamectin (Avermectin B1a)","C48H72O14","CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C","InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1","organic","compound","PubChem isomeric SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","mixture or formulation","Component is part of a mixture or forumlation","Avermectin B1a","265-610-3","65195-55-3","(2aZ,4Z,5?S,6S,6?R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6?-[(2S)-butan-2-yl]-20,20b-dihydroxy-5?,6,8,19-tetramethyl-17-oxo-5?,6,6?,10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2?-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Abamectin (Avermectin B1a)","C48H72O14","CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C","InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1","organic","compound","PubChem isomeric SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","mixture or formulation","Component is part of a mixture or forumlation","Avermectin B1a","265-610-3","65195-55-3","(2aZ,4Z,5?S,6S,6?R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6?-[(2S)-butan-2-yl]-20,20b-dihydroxy-5?,6,8,19-tetramethyl-17-oxo-5?,6,6?,10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2?-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Abamectin (Avermectin B1a)","C48H72O14","CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C","InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1","organic","compound","PubChem isomeric SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","mixture or formulation","Component is part of a mixture or forumlation","Avermectin B1a","265-610-3","65195-55-3","(2aZ,4Z,5?S,6S,6?R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6?-[(2S)-butan-2-yl]-20,20b-dihydroxy-5?,6,8,19-tetramethyl-17-oxo-5?,6,6?,10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2?-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Abamectin (Avermectin B1a)","C48H72O14","CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C","InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1","organic","compound","PubChem isomeric SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1538","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","mixture or formulation","Component is part of a mixture or forumlation","Avermectin B1a","265-610-3","65195-55-3","(2aZ,4Z,5?S,6S,6?R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6?-[(2S)-butan-2-yl]-20,20b-dihydroxy-5?,6,8,19-tetramethyl-17-oxo-5?,6,6?,10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2?-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Abamectin (Avermectin B1a)","C48H72O14","CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C","InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1","organic","compound","PubChem isomeric SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","mixture or formulation","Component is part of a mixture or forumlation","Avermectin B1a","265-610-3","65195-55-3","(2aZ,4Z,5?S,6S,6?R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6?-[(2S)-butan-2-yl]-20,20b-dihydroxy-5?,6,8,19-tetramethyl-17-oxo-5?,6,6?,10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2?-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Abamectin (Avermectin B1a)","C48H72O14","CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C","InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1","organic","compound","PubChem isomeric SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","mixture or formulation","Component is part of a mixture or forumlation","Avermectin B1a","265-610-3","65195-55-3","(2aZ,4Z,5?S,6S,6?R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6?-[(2S)-butan-2-yl]-20,20b-dihydroxy-5?,6,8,19-tetramethyl-17-oxo-5?,6,6?,10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2?-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Abamectin (Avermectin B1a)","C48H72O14","CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C","InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1","organic","compound","PubChem isomeric SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","mixture or formulation","Component is part of a mixture or forumlation","Avermectin B1a","265-610-3","65195-55-3","(2aZ,4Z,5?S,6S,6?R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6?-[(2S)-butan-2-yl]-20,20b-dihydroxy-5?,6,8,19-tetramethyl-17-oxo-5?,6,6?,10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2?-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Abamectin (Avermectin B1a)","C48H72O14","CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C","InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1","organic","compound","PubChem isomeric SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","Equivalent or similar to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","Yes","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","mixture or formulation","Component is part of a mixture or forumlation","Avermectin B1a","265-610-3","65195-55-3","(2aZ,4Z,5?S,6S,6?R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6?-[(2S)-butan-2-yl]-20,20b-dihydroxy-5?,6,8,19-tetramethyl-17-oxo-5?,6,6?,10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2?-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Abamectin (Avermectin B1a)","C48H72O14","CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C","InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1","organic","compound","PubChem isomeric SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","Equivalent or similar to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","Yes","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","mixture or formulation","Component is identical to the substance","Abamectin","","71751-41-2","(9Z,13Z,15Z)-6?-(butan-2-yl)-19,21b-dihydroxy-5?,10,12,20-tetramethyl-1-oxo-3,4,5?,6?,8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2?-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside","Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)","C49H74O14","CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C","InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-","organic","representative compound","PubChem canonical SMILES","PubChem InChI","gene mutation","mammalian cell gene mutation assay","in vitro","Equivalent or similar to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","Yes","Acceptable","Hamster (as animal)","lung fibroblasts (V79)","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","mixture or formulation","Component is identical to the substance","Abamectin","","71751-41-2","(9Z,13Z,15Z)-6?-(butan-2-yl)-19,21b-dihydroxy-5?,10,12,20-tetramethyl-1-oxo-3,4,5?,6?,8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2?-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside","Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)","C49H74O14","CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C","InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-","organic","representative compound","PubChem canonical SMILES","PubChem InChI","gene mutation","mammalian cell gene mutation assay","in vitro","Equivalent or similar to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","Yes","Acceptable","Hamster (as animal)","lung fibroblasts (V79)","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","mixture or formulation","Component is identical to the substance","Abamectin","","71751-41-2","(9Z,13Z,15Z)-6?-(butan-2-yl)-19,21b-dihydroxy-5?,10,12,20-tetramethyl-1-oxo-3,4,5?,6?,8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2?-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside","Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)","C49H74O14","CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C","InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-","organic","representative compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","chromosome aberration assay","in vivo","Equivalent or similar to","OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)","Yes","Acceptable","House mouse (as animal)","CD-1","","Male","Not reported","24","h","yes","not applicable","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","mixture or formulation","Component is part of a mixture or forumlation","Avermectin B1a","265-610-3","65195-55-3","(2aZ,4Z,5'S,6S,6'R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17-oxo-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Abamectin (Avermectin B1a)","C48H72O14","CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C","InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1","organic","compound","PubChem isomeric SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","mixture or formulation","Component is part of a mixture or forumlation","Avermectin B1a","265-610-3","65195-55-3","(2aZ,4Z,5'S,6S,6'R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17-oxo-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Abamectin (Avermectin B1a)","C48H72O14","CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C","InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1","organic","compound","PubChem isomeric SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","mixture or formulation","Component is part of a mixture or forumlation","Avermectin B1a","265-610-3","65195-55-3","(2aZ,4Z,5'S,6S,6'R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17-oxo-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Abamectin (Avermectin B1a)","C48H72O14","CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C","InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1","organic","compound","PubChem isomeric SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1538","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","mixture or formulation","Component is part of a mixture or forumlation","Avermectin B1a","265-610-3","65195-55-3","(2aZ,4Z,5'S,6S,6'R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17-oxo-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Abamectin (Avermectin B1a)","C48H72O14","CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C","InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1","organic","compound","PubChem isomeric SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","mixture or formulation","Component is part of a mixture or forumlation","Avermectin B1a","265-610-3","65195-55-3","(2aZ,4Z,5'S,6S,6'R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17-oxo-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Abamectin (Avermectin B1a)","C48H72O14","CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C","InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1","organic","compound","PubChem isomeric SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","mixture or formulation","Component is part of a mixture or forumlation","Avermectin B1a","265-610-3","65195-55-3","(2aZ,4Z,5'S,6S,6'R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17-oxo-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Abamectin (Avermectin B1a)","C48H72O14","CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C","InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1","organic","compound","PubChem isomeric SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","mixture or formulation","Component is part of a mixture or forumlation","Avermectin B1a","265-610-3","65195-55-3","(2aZ,4Z,5'S,6S,6'R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17-oxo-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Abamectin (Avermectin B1a)","C48H72O14","CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C","InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1","organic","compound","PubChem isomeric SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1538","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","mixture or formulation","Component is part of a mixture or forumlation","Avermectin B1a","265-610-3","65195-55-3","(2aZ,4Z,5'S,6S,6'R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17-oxo-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Abamectin (Avermectin B1a)","C48H72O14","CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C","InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1","organic","compound","PubChem isomeric SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","mixture or formulation","Component is part of a mixture or forumlation","Avermectin B1a","265-610-3","65195-55-3","(2aZ,4Z,5'S,6S,6'R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17-oxo-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Abamectin (Avermectin B1a)","C48H72O14","CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C","InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1","organic","compound","PubChem isomeric SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","mixture or formulation","Component is part of a mixture or forumlation","Avermectin B1a","265-610-3","65195-55-3","(2aZ,4Z,5'S,6S,6'R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17-oxo-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Abamectin (Avermectin B1a)","C48H72O14","CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C","InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1","organic","compound","PubChem isomeric SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","mixture or formulation","Component is part of a mixture or forumlation","Avermectin B1a","265-610-3","65195-55-3","(2aZ,4Z,5'S,6S,6'R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17-oxo-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Abamectin (Avermectin B1a)","C48H72O14","CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C","InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1","organic","compound","PubChem isomeric SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","Equivalent or similar to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","Yes","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","mixture or formulation","Component is part of a mixture or forumlation","Avermectin B1a","265-610-3","65195-55-3","(2aZ,4Z,5'S,6S,6'R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17-oxo-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Abamectin (Avermectin B1a)","C48H72O14","CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C","InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1","organic","compound","PubChem isomeric SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","Equivalent or similar to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","Yes","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","mixture or formulation","Component is identical to the substance","Abamectin","","71751-41-2","(9Z,13Z,15Z)-6'-(butan-2-yl)-19,21b-dihydroxy-5',10,12,20-tetramethyl-1-oxo-3,4,5',6',8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2'-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside","Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)","C49H74O14","CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C","InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-","organic","representative compound","PubChem canonical SMILES","PubChem InChI","gene mutation","mammalian cell gene mutation assay","in vitro","Equivalent or similar to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","Yes","Acceptable","Hamster (as animal)","lung fibroblasts (V79)","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","mixture or formulation","Component is identical to the substance","Abamectin","","71751-41-2","(9Z,13Z,15Z)-6'-(butan-2-yl)-19,21b-dihydroxy-5',10,12,20-tetramethyl-1-oxo-3,4,5',6',8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2'-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside","Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)","C49H74O14","CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C","InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-","organic","representative compound","PubChem canonical SMILES","PubChem InChI","gene mutation","mammalian cell gene mutation assay","in vitro","Equivalent or similar to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","Yes","Acceptable","Hamster (as animal)","lung fibroblasts (V79)","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","mixture or formulation","Component is identical to the substance","Abamectin","","71751-41-2","(9Z,13Z,15Z)-6'-(butan-2-yl)-19,21b-dihydroxy-5',10,12,20-tetramethyl-1-oxo-3,4,5',6',8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2'-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside","Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)","C49H74O14","CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C","InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-","organic","representative compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","chromosome aberration assay","in vivo","Equivalent or similar to","OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)","Yes","Acceptable","House mouse (as animal)","CD-1","","Male","Not reported","24","h","yes","not applicable","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" "Acequinocyl","","57960-19-7","single chemical entity","Component is identical to the substance","Acequinocyl","","57960-19-7","3-dodecyl-1,4-dioxo-1,4-dihydronaphthalen-2-yl acetate","Acequinocyl","C24H32O4","CC(=O)OC2=C(CCCCCCCCCCCC)C(=O)c1ccccc1C2=O","InChI=1S/C24H32O4/c1-3-4-5-6-7-8-9-10-11-12-17-21-22(26)19-15-13-14-16-20(19)23(27)24(21)28-18(2)25/h13-16H,3-12,17H2,1-2H3","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Hamster (as animal)","lung fibroblasts (V79)","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Acequinocyl (Revised version of September 2007)","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl.","41396","2013","doi:10.2903/j.efsa.2013.3212" "Acequinocyl","","57960-19-7","single chemical entity","Component is identical to the substance","Acequinocyl","","57960-19-7","3-dodecyl-1,4-dioxo-1,4-dihydronaphthalen-2-yl acetate","Acequinocyl","C24H32O4","CC(=O)OC2=C(CCCCCCCCCCCC)C(=O)c1ccccc1C2=O","InChI=1S/C24H32O4/c1-3-4-5-6-7-8-9-10-11-12-17-21-22(26)19-15-13-14-16-20(19)23(27)24(21)28-18(2)25/h13-16H,3-12,17H2,1-2H3","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Hamster (as animal)","lung fibroblasts (V79)","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Acequinocyl (Revised version of September 2007)","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl.","41396","2013","doi:10.2903/j.efsa.2013.3212" "Acequinocyl","","57960-19-7","single chemical entity","Component is identical to the substance","Acequinocyl","","57960-19-7","3-dodecyl-1,4-dioxo-1,4-dihydronaphthalen-2-yl acetate","Acequinocyl","C24H32O4","CC(=O)OC2=C(CCCCCCCCCCCC)C(=O)c1ccccc1C2=O","InChI=1S/C24H32O4/c1-3-4-5-6-7-8-9-10-11-12-17-21-22(26)19-15-13-14-16-20(19)23(27)24(21)28-18(2)25/h13-16H,3-12,17H2,1-2H3","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","House mouse (as animal)","lymphoma L5178Y cells","","","Not reported","","","yes","without","Negative","no information","","RMS: The Netherlands","Acequinocyl (Revised addendum)","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl.","41396","2013","doi:10.2903/j.efsa.2013.3212" @@ -348,22 +348,22 @@ "Amisulbrom","","348635-87-0","single chemical entity","Component is identical to the substance","Amisulbrom","","348635-87-0","3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1,2,4-triazole-1-sulfonamide","Amisulbrom","C13H13BrFN5O4S2","CC1=C(C2=C(N1S(=O)(=O)C3=NN(C=N3)S(=O)(=O)N(C)C)C=C(C=C2)F)Br","InChI=1S/C13H13BrFN5O4S2/c1-8-12(14)10-5-4-9(15)6-11(10)20(8)25(21,22)13-16-7-19(17-13)26(23,24)18(2)3/h4-7H,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","single cell gel/comet assay in mammalian cells for detection of DNA damage","in vivo","Equivalent or similar to","OECD Guideline 489","Yes","Acceptable","Rat (as animal)","Wistar","4","Female","oral: gavage","24","h","yes","not applicable","Negative","","","RMS: The United Kingdom","Amisulbrom","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom","41736","2014","doi:10.2903/j.efsa.2014.3237" "Amisulbrom","","348635-87-0","single chemical entity","Component is identical to the substance","Amisulbrom","","348635-87-0","3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1,2,4-triazole-1-sulfonamide","Amisulbrom","C13H13BrFN5O4S2","CC1=C(C2=C(N1S(=O)(=O)C3=NN(C=N3)S(=O)(=O)N(C)C)C=C(C=C2)F)Br","InChI=1S/C13H13BrFN5O4S2/c1-8-12(14)10-5-4-9(15)6-11(10)20(8)25(21,22)13-16-7-19(17-13)26(23,24)18(2)3/h4-7H,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","CD-1","6","Male","intraperitoneal","24","h","yes","not applicable","Negative","","direct evidence-cytotoxicity$indirect evidence-systemic toxicity","RMS: The United Kingdom","Amisulbrom","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom","41736","2014","doi:10.2903/j.efsa.2014.3237" "Amisulbrom","","348635-87-0","single chemical entity","Component is identical to the substance","Amisulbrom","","348635-87-0","3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1,2,4-triazole-1-sulfonamide","Amisulbrom","C13H13BrFN5O4S2","CC1=C(C2=C(N1S(=O)(=O)C3=NN(C=N3)S(=O)(=O)N(C)C)C=C(C=C2)F)Br","InChI=1S/C13H13BrFN5O4S2/c1-8-12(14)10-5-4-9(15)6-11(10)20(8)25(21,22)13-16-7-19(17-13)26(23,24)18(2)3/h4-7H,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","Equivalent or similar to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","Yes","Acceptable","House mouse (as animal)","CD-1","6","Male","oral: gavage","24","h","yes","not applicable","Negative","","no evidence","RMS: The United Kingdom","Amisulbrom","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom","41736","2014","doi:10.2903/j.efsa.2014.3237" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","with","Positive","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","without","Positive","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","CD-1","10","Male/Female","oral: gavage","24","h","yes, concurrent vehicle","not applicable","Negative","","direct evidence-cytotoxicity","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","CD-1","10","Male/Female","oral: gavage","72","h","yes, concurrent vehicle","not applicable","Negative","","direct evidence-cytotoxicity","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","CD-1","10","Male/Female","oral: gavage","48","h","yes, concurrent vehicle","not applicable","Negative","","direct evidence-cytotoxicity","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","without","Positive","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","with","Positive","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","CD-1","10","Male/Female","oral: gavage","72","h","yes, concurrent vehicle","not applicable","Negative","","direct evidence-cytotoxicity$indirect evidence-systemic toxicity","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","CD-1","10","Male/Female","oral: gavage","24","h","yes, concurrent vehicle","not applicable","Negative","","direct evidence-cytotoxicity$indirect evidence-systemic toxicity","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","CD-1","10","Male/Female","oral: gavage","48","h","yes, concurrent vehicle","not applicable","Negative","","direct evidence-cytotoxicity$indirect evidence-systemic toxicity","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","without","Positive","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","with","Positive","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","without","Positive","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","CD-1","10","Male/Female","oral: gavage","24","h","yes, concurrent vehicle","not applicable","Negative","","direct evidence-cytotoxicity","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","CD-1","10","Male/Female","oral: gavage","72","h","yes, concurrent vehicle","not applicable","Negative","","direct evidence-cytotoxicity","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","CD-1","10","Male/Female","oral: gavage","48","h","yes, concurrent vehicle","not applicable","Negative","","direct evidence-cytotoxicity","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","without","Positive","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","with","Positive","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","CD-1","10","Male/Female","oral: gavage","72","h","yes, concurrent vehicle","not applicable","Negative","","direct evidence-cytotoxicity$indirect evidence-systemic toxicity","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","CD-1","10","Male/Female","oral: gavage","24","h","yes, concurrent vehicle","not applicable","Negative","","direct evidence-cytotoxicity$indirect evidence-systemic toxicity","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","CD-1","10","Male/Female","oral: gavage","48","h","yes, concurrent vehicle","not applicable","Negative","","direct evidence-cytotoxicity$indirect evidence-systemic toxicity","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","without","Positive","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" "Azimsulfuron","601-676-5","120162-55-2","single chemical entity","Component is identical to the substance","Azimsulfuron","601-676-5","120162-55-2","N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide","Azimsulfuron","C13H16N10O5S","Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(OC)cc(OC)n3","InChI=1S/C13H16N10O5S/c1-22-11(7(6-14-22)10-18-21-23(2)19-10)29(25,26)20-13(24)17-12-15-8(27-3)5-9(16-12)28-4/h5-6H,1-4H3,(H2,15,16,17,20,24)","organic","compound","Other","Other","DNA damage and/or repair","DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro","in vitro","According to","OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)","No","Acceptable","Rat (as animal)","hepatocytes","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Sweden - CoRMS: Slovenia","Azimsulfuron (Corrigendum)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron","40263","2010","doi:10.2903/j.efsa.2010.1554" "Azimsulfuron","601-676-5","120162-55-2","single chemical entity","Component is a metabolite of the substance","N-[[(4-hydroxy-6-methoxypyrimidin-2-yl)amino]carbonyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide","","","N-[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide","Not in list","C12H14N10O5S","Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(O)cc(OC)n3","InChI=1S/C12H14N10O5S/c1-21-10(6(5-13-21)9-17-20-22(2)18-9)28(25,26)19-12(24)16-11-14-7(23)4-8(15-11)27-3/h4-5H,1-3H3,(H3,14,15,16,19,23,24)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 97","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Sweden - CoRMS: Slovenia","Azimsulfuron (Corrigendum)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron","40263","2010","doi:10.2903/j.efsa.2010.1554" "Azimsulfuron","601-676-5","120162-55-2","single chemical entity","Component is a metabolite of the substance","N-[[(4-hydroxy-6-methoxypyrimidin-2-yl)amino]carbonyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide","","","N-[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide","Not in list","C12H14N10O5S","Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(O)cc(OC)n3","InChI=1S/C12H14N10O5S/c1-21-10(6(5-13-21)9-17-20-22(2)18-9)28(25,26)19-12(24)16-11-14-7(23)4-8(15-11)27-3/h4-5H,1-3H3,(H3,14,15,16,19,23,24)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Sweden - CoRMS: Slovenia","Azimsulfuron (Corrigendum)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron","40263","2010","doi:10.2903/j.efsa.2010.1554" @@ -586,21 +586,21 @@ "Bitertanol","259-513-5","55179-31-2","single chemical entity","Component is identical to the substance","Bitertanol","259-513-5","55179-31-2","1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol","Bitertanol","C20H23N3O2","CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3","InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3","organic","compound","Other","Other","chromosome aberration","other","in vitro","No guideline available","Not reported","Not applicable","Acceptable","Sordaria brevicollis (as organism)","Not reported","","","Not reported","","","yes","without","Negative","","","RMS: The United Kingdom","Bitertanol","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol","40476","2010","doi:10.2903/j.efsa.2010.1850" "Bitertanol","259-513-5","55179-31-2","single chemical entity","Component is identical to the substance","Bitertanol","259-513-5","55179-31-2","1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol","Bitertanol","C20H23N3O2","CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3","InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","Equivalent or similar to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","Yes","Acceptable","House mouse (as animal)","NMRI","","Male/Female","oral: gavage","6","h","no data","not applicable","Negative","","no evidence","RMS: The United Kingdom","Bitertanol","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol","40476","2010","doi:10.2903/j.efsa.2010.1850" "Bitertanol","259-513-5","55179-31-2","single chemical entity","Component is identical to the substance","Bitertanol","259-513-5","55179-31-2","1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol","Bitertanol","C20H23N3O2","CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3","InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3","organic","compound","Other","Other","chromosome aberration","dominant lethal assay","in vivo","According to","OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)","No","Acceptable","House mouse (as animal)","NMRI","50","Male","oral: unspecified","","","yes","not applicable","Negative","","","RMS: The United Kingdom","Bitertanol","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol","40476","2010","doi:10.2903/j.efsa.2010.1850" -"Bixafen","","581809-46-3","single chemical entity","Component is identical to the substance","Bixafen","","581809-46-3","N-(3?,4?-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Bixafen","C18H12Cl2F3N3O","FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1","InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 102","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Bixafen","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen","41218","2012","doi:10.2903/j.efsa.2012.2917" -"Bixafen","","581809-46-3","single chemical entity","Component is identical to the substance","Bixafen","","581809-46-3","N-(3?,4?-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Bixafen","C18H12Cl2F3N3O","FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1","InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Bixafen","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen","41218","2012","doi:10.2903/j.efsa.2012.2917" -"Bixafen","","581809-46-3","single chemical entity","Component is identical to the substance","Bixafen","","581809-46-3","N-(3?,4?-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Bixafen","C18H12Cl2F3N3O","FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1","InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Bixafen","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen","41218","2012","doi:10.2903/j.efsa.2012.2917" -"Bixafen","","581809-46-3","single chemical entity","Component is identical to the substance","Bixafen","","581809-46-3","N-(3?,4?-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Bixafen","C18H12Cl2F3N3O","FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1","InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Bixafen","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen","41218","2012","doi:10.2903/j.efsa.2012.2917" -"Bixafen","","581809-46-3","single chemical entity","Component is identical to the substance","Bixafen","","581809-46-3","N-(3?,4?-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Bixafen","C18H12Cl2F3N3O","FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1","InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 102","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Bixafen","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen","41218","2012","doi:10.2903/j.efsa.2012.2917" -"Bixafen","","581809-46-3","single chemical entity","Component is identical to the substance","Bixafen","","581809-46-3","N-(3?,4?-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Bixafen","C18H12Cl2F3N3O","FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1","InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Bixafen","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen","41218","2012","doi:10.2903/j.efsa.2012.2917" -"Bixafen","","581809-46-3","single chemical entity","Component is identical to the substance","Bixafen","","581809-46-3","N-(3?,4?-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Bixafen","C18H12Cl2F3N3O","FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1","InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Bixafen","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen","41218","2012","doi:10.2903/j.efsa.2012.2917" -"Bixafen","","581809-46-3","single chemical entity","Component is identical to the substance","Bixafen","","581809-46-3","N-(3?,4?-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Bixafen","C18H12Cl2F3N3O","FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1","InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Bixafen","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen","41218","2012","doi:10.2903/j.efsa.2012.2917" -"Bixafen","","581809-46-3","single chemical entity","Component is identical to the substance","Bixafen","","581809-46-3","N-(3?,4?-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Bixafen","C18H12Cl2F3N3O","FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1","InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Bixafen","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen","41218","2012","doi:10.2903/j.efsa.2012.2917" -"Bixafen","","581809-46-3","single chemical entity","Component is identical to the substance","Bixafen","","581809-46-3","N-(3?,4?-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Bixafen","C18H12Cl2F3N3O","FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1","InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Bixafen","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen","41218","2012","doi:10.2903/j.efsa.2012.2917" -"Bixafen","","581809-46-3","single chemical entity","Component is identical to the substance","Bixafen","","581809-46-3","N-(3?,4?-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Bixafen","C18H12Cl2F3N3O","FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1","InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","lung fibroblasts (V79)","","","Not reported","","","yes","with","Negative","","","RMS: The United Kingdom","Bixafen","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen","41218","2012","doi:10.2903/j.efsa.2012.2917" -"Bixafen","","581809-46-3","single chemical entity","Component is identical to the substance","Bixafen","","581809-46-3","N-(3?,4?-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Bixafen","C18H12Cl2F3N3O","FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1","InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","lung fibroblasts (V79)","","","Not reported","","","yes","without","Negative","","","RMS: The United Kingdom","Bixafen","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen","41218","2012","doi:10.2903/j.efsa.2012.2917" -"Bixafen","","581809-46-3","single chemical entity","Component is identical to the substance","Bixafen","","581809-46-3","N-(3?,4?-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Bixafen","C18H12Cl2F3N3O","FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1","InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Hamster (as animal)","lung fibroblasts (V79)","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Bixafen","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen","41218","2012","doi:10.2903/j.efsa.2012.2917" -"Bixafen","","581809-46-3","single chemical entity","Component is identical to the substance","Bixafen","","581809-46-3","N-(3?,4?-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Bixafen","C18H12Cl2F3N3O","FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1","InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Hamster (as animal)","lung fibroblasts (V79)","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Bixafen","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen","41218","2012","doi:10.2903/j.efsa.2012.2917" -"Bixafen","","581809-46-3","single chemical entity","Component is identical to the substance","Bixafen","","581809-46-3","N-(3?,4?-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Bixafen","C18H12Cl2F3N3O","FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1","InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","NMRI","5","Male","intraperitoneal","24","h","yes, concurrent vehicle","not applicable","Negative","","indirect evidence-systemic toxicity","RMS: The United Kingdom","Bixafen","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen","41218","2012","doi:10.2903/j.efsa.2012.2917" +"Bixafen","","581809-46-3","single chemical entity","Component is identical to the substance","Bixafen","","581809-46-3","N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Bixafen","C18H12Cl2F3N3O","FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1","InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 102","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Bixafen","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen","41218","2012","doi:10.2903/j.efsa.2012.2917" +"Bixafen","","581809-46-3","single chemical entity","Component is identical to the substance","Bixafen","","581809-46-3","N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Bixafen","C18H12Cl2F3N3O","FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1","InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Bixafen","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen","41218","2012","doi:10.2903/j.efsa.2012.2917" +"Bixafen","","581809-46-3","single chemical entity","Component is identical to the substance","Bixafen","","581809-46-3","N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Bixafen","C18H12Cl2F3N3O","FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1","InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Bixafen","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen","41218","2012","doi:10.2903/j.efsa.2012.2917" +"Bixafen","","581809-46-3","single chemical entity","Component is identical to the substance","Bixafen","","581809-46-3","N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Bixafen","C18H12Cl2F3N3O","FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1","InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Bixafen","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen","41218","2012","doi:10.2903/j.efsa.2012.2917" +"Bixafen","","581809-46-3","single chemical entity","Component is identical to the substance","Bixafen","","581809-46-3","N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Bixafen","C18H12Cl2F3N3O","FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1","InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 102","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Bixafen","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen","41218","2012","doi:10.2903/j.efsa.2012.2917" +"Bixafen","","581809-46-3","single chemical entity","Component is identical to the substance","Bixafen","","581809-46-3","N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Bixafen","C18H12Cl2F3N3O","FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1","InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Bixafen","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen","41218","2012","doi:10.2903/j.efsa.2012.2917" +"Bixafen","","581809-46-3","single chemical entity","Component is identical to the substance","Bixafen","","581809-46-3","N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Bixafen","C18H12Cl2F3N3O","FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1","InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Bixafen","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen","41218","2012","doi:10.2903/j.efsa.2012.2917" +"Bixafen","","581809-46-3","single chemical entity","Component is identical to the substance","Bixafen","","581809-46-3","N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Bixafen","C18H12Cl2F3N3O","FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1","InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Bixafen","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen","41218","2012","doi:10.2903/j.efsa.2012.2917" +"Bixafen","","581809-46-3","single chemical entity","Component is identical to the substance","Bixafen","","581809-46-3","N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Bixafen","C18H12Cl2F3N3O","FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1","InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Bixafen","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen","41218","2012","doi:10.2903/j.efsa.2012.2917" +"Bixafen","","581809-46-3","single chemical entity","Component is identical to the substance","Bixafen","","581809-46-3","N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Bixafen","C18H12Cl2F3N3O","FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1","InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Bixafen","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen","41218","2012","doi:10.2903/j.efsa.2012.2917" +"Bixafen","","581809-46-3","single chemical entity","Component is identical to the substance","Bixafen","","581809-46-3","N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Bixafen","C18H12Cl2F3N3O","FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1","InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","lung fibroblasts (V79)","","","Not reported","","","yes","with","Negative","","","RMS: The United Kingdom","Bixafen","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen","41218","2012","doi:10.2903/j.efsa.2012.2917" +"Bixafen","","581809-46-3","single chemical entity","Component is identical to the substance","Bixafen","","581809-46-3","N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Bixafen","C18H12Cl2F3N3O","FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1","InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","lung fibroblasts (V79)","","","Not reported","","","yes","without","Negative","","","RMS: The United Kingdom","Bixafen","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen","41218","2012","doi:10.2903/j.efsa.2012.2917" +"Bixafen","","581809-46-3","single chemical entity","Component is identical to the substance","Bixafen","","581809-46-3","N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Bixafen","C18H12Cl2F3N3O","FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1","InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Hamster (as animal)","lung fibroblasts (V79)","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Bixafen","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen","41218","2012","doi:10.2903/j.efsa.2012.2917" +"Bixafen","","581809-46-3","single chemical entity","Component is identical to the substance","Bixafen","","581809-46-3","N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Bixafen","C18H12Cl2F3N3O","FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1","InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Hamster (as animal)","lung fibroblasts (V79)","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Bixafen","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen","41218","2012","doi:10.2903/j.efsa.2012.2917" +"Bixafen","","581809-46-3","single chemical entity","Component is identical to the substance","Bixafen","","581809-46-3","N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Bixafen","C18H12Cl2F3N3O","FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1","InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","NMRI","5","Male","intraperitoneal","24","h","yes, concurrent vehicle","not applicable","Negative","","indirect evidence-systemic toxicity","RMS: The United Kingdom","Bixafen","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen","41218","2012","doi:10.2903/j.efsa.2012.2917" "Bromadiolone","249-205-9","28772-56-7","single chemical entity","Component is identical to the substance","Bromadiolone","249-205-9","28772-56-7","3-[3-[4-(4-Bromophenyl)phenyl]-3-hydroxy-1-phenylpropyl]-4- hydroxychromen-2-one","Bromadiolone","C30H23BrO4","C1=CC=C(C=C1)C(CC(C2=CC=C(C=C2)C3=CC=C(C=C3)Br)O)C4=C(C5=CC=CC=C5OC4=O)O","InChI=1S/C30H23BrO4/c31-23-16-14-20(15-17-23)19-10-12-22(13-11-19)26(32)18-25(21-6-2-1-3-7-21)28-29(33)24-8-4-5-9-27(24)35-30(28)34/h1-17,25-26,32-33H,18H2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Sweden","Bromadiolone","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bromadiolone","40464","2010","doi:10.2903/j.efsa.2010.1783" "Bromadiolone","249-205-9","28772-56-7","single chemical entity","Component is identical to the substance","Bromadiolone","249-205-9","28772-56-7","3-[3-[4-(4-Bromophenyl)phenyl]-3-hydroxy-1-phenylpropyl]-4- @@ -911,32 +911,32 @@ hydroxychromen-2-one","Bromadiolone","C30H23BrO4","C1=CC=C(C=C1)C(CC(C2=CC=C(C=C "8-Hydroxyquinoline","205-711-1","148-24-3","single chemical entity","Component is identical to the substance","8-Hydroxyquinoline","205-711-1","148-24-3","Quinolin-8-ol","Not in list","C9H7NO","C1=CC2=C(C(=C1)O)N=CC=C2","InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Spain","8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline","40571","2011","doi:10.2903/j.efsa.2011.1964" "8-Hydroxyquinoline","205-711-1","148-24-3","single chemical entity","Component is identical to the substance","8-Hydroxyquinoline","205-711-1","148-24-3","Quinolin-8-ol","Not in list","C9H7NO","C1=CC2=C(C(=C1)O)N=CC=C2","InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","sister chromatid exchange assay in mammalian cells","in vivo","No guideline available","Not reported","Not applicable","Acceptable","House mouse (as animal)","B6C3F1","4","Male","intraperitoneal","23","h","yes, concurrent vehicle","not applicable","Negative","","","RMS: Spain","8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline","40571","2011","doi:10.2903/j.efsa.2011.1964" "8-Hydroxyquinoline","205-711-1","148-24-3","single chemical entity","Component is identical to the substance","8-Hydroxyquinoline","205-711-1","148-24-3","Quinolin-8-ol","Not in list","C9H7NO","C1=CC2=C(C(=C1)O)N=CC=C2","InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","sister chromatid exchange assay in mammalian cells","in vivo","No guideline available","Not reported","Not applicable","Acceptable","House mouse (as animal)","B6C3F1","4","Male","intraperitoneal","42","h","yes, concurrent vehicle","not applicable","Negative","","","RMS: Spain","8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline","40571","2011","doi:10.2903/j.efsa.2011.1964" -"Abamectin","","71751-41-2","mixture or formulation","Component is identical to the substance","Abamectin","","71751-41-2","(9Z,13Z,15Z)-6?-(butan-2-yl)-19,21b-dihydroxy-5?,10,12,20-tetramethyl-1-oxo-3,4,5?,6?,8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2?-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside","Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)","C49H74O14","CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C","InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-","organic","representative compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","mixture or formulation","Component is identical to the substance","Abamectin","","71751-41-2","(9Z,13Z,15Z)-6?-(butan-2-yl)-19,21b-dihydroxy-5?,10,12,20-tetramethyl-1-oxo-3,4,5?,6?,8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2?-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside","Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)","C49H74O14","CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C","InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-","organic","representative compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","mixture or formulation","Component is identical to the substance","Abamectin","","71751-41-2","(9Z,13Z,15Z)-6?-(butan-2-yl)-19,21b-dihydroxy-5?,10,12,20-tetramethyl-1-oxo-3,4,5?,6?,8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2?-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside","Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)","C49H74O14","CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C","InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-","organic","representative compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","mixture or formulation","Component is identical to the substance","Abamectin","","71751-41-2","(9Z,13Z,15Z)-6?-(butan-2-yl)-19,21b-dihydroxy-5?,10,12,20-tetramethyl-1-oxo-3,4,5?,6?,8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2?-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside","Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)","C49H74O14","CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C","InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-","organic","representative compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","mixture or formulation","Component is identical to the substance","Abamectin","","71751-41-2","(9Z,13Z,15Z)-6?-(butan-2-yl)-19,21b-dihydroxy-5?,10,12,20-tetramethyl-1-oxo-3,4,5?,6?,8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2?-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside","Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)","C49H74O14","CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C","InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-","organic","representative compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 102","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","mixture or formulation","Component is identical to the substance","Abamectin","","71751-41-2","(9Z,13Z,15Z)-6?-(butan-2-yl)-19,21b-dihydroxy-5?,10,12,20-tetramethyl-1-oxo-3,4,5?,6?,8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2?-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside","Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)","C49H74O14","CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C","InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-","organic","representative compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","mixture or formulation","Component is identical to the substance","Abamectin","","71751-41-2","(9Z,13Z,15Z)-6?-(butan-2-yl)-19,21b-dihydroxy-5?,10,12,20-tetramethyl-1-oxo-3,4,5?,6?,8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2?-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside","Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)","C49H74O14","CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C","InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-","organic","representative compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 102","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","mixture or formulation","Component is identical to the substance","Abamectin","","71751-41-2","(9Z,13Z,15Z)-6?-(butan-2-yl)-19,21b-dihydroxy-5?,10,12,20-tetramethyl-1-oxo-3,4,5?,6?,8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2?-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside","Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)","C49H74O14","CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C","InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-","organic","representative compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","mixture or formulation","Component is identical to the substance","Abamectin","","71751-41-2","(9Z,13Z,15Z)-6?-(butan-2-yl)-19,21b-dihydroxy-5?,10,12,20-tetramethyl-1-oxo-3,4,5?,6?,8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2?-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside","Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)","C49H74O14","CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C","InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-","organic","representative compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","mixture or formulation","Component is identical to the substance","Abamectin","","71751-41-2","(9Z,13Z,15Z)-6?-(butan-2-yl)-19,21b-dihydroxy-5?,10,12,20-tetramethyl-1-oxo-3,4,5?,6?,8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2?-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside","Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)","C49H74O14","CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C","InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-","organic","representative compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","mixture or formulation","Component is identical to the substance","Abamectin","","71751-41-2","(9Z,13Z,15Z)-6?-(butan-2-yl)-19,21b-dihydroxy-5?,10,12,20-tetramethyl-1-oxo-3,4,5?,6?,8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2?-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside","Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)","C49H74O14","CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C","InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-","organic","representative compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","mixture or formulation","Component is identical to the substance","Abamectin","","71751-41-2","(9Z,13Z,15Z)-6?-(butan-2-yl)-19,21b-dihydroxy-5?,10,12,20-tetramethyl-1-oxo-3,4,5?,6?,8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2?-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside","Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)","C49H74O14","CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C","InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-","organic","representative compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","single chemical entity","Component is a metabolite of the substance","[8,9-Z]-isomer of avermectin B1a","","","{(2aZ,4Z,5?S,6R,6?R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6?-[(2S)-butan-2-yl]-19,19b-dihydroxy-5?,6,7,18-tetramethyl-16-oxo-5?,6,6?,9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2?-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Avermectin B1a, delta-8,9 isomer","C47H70O14","CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O","InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","single chemical entity","Component is a metabolite of the substance","[8,9-Z]-isomer of avermectin B1a","","","{(2aZ,4Z,5?S,6R,6?R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6?-[(2S)-butan-2-yl]-19,19b-dihydroxy-5?,6,7,18-tetramethyl-16-oxo-5?,6,6?,9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2?-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Avermectin B1a, delta-8,9 isomer","C47H70O14","CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O","InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","single chemical entity","Component is a metabolite of the substance","[8,9-Z]-isomer of avermectin B1a","","","{(2aZ,4Z,5?S,6R,6?R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6?-[(2S)-butan-2-yl]-19,19b-dihydroxy-5?,6,7,18-tetramethyl-16-oxo-5?,6,6?,9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2?-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Avermectin B1a, delta-8,9 isomer","C47H70O14","CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O","InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 97","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","single chemical entity","Component is a metabolite of the substance","[8,9-Z]-isomer of avermectin B1a","","","{(2aZ,4Z,5?S,6R,6?R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6?-[(2S)-butan-2-yl]-19,19b-dihydroxy-5?,6,7,18-tetramethyl-16-oxo-5?,6,6?,9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2?-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Avermectin B1a, delta-8,9 isomer","C47H70O14","CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O","InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","single chemical entity","Component is a metabolite of the substance","[8,9-Z]-isomer of avermectin B1a","","","{(2aZ,4Z,5?S,6R,6?R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6?-[(2S)-butan-2-yl]-19,19b-dihydroxy-5?,6,7,18-tetramethyl-16-oxo-5?,6,6?,9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2?-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Avermectin B1a, delta-8,9 isomer","C47H70O14","CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O","InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","single chemical entity","Component is a metabolite of the substance","[8,9-Z]-isomer of avermectin B1a","","","{(2aZ,4Z,5?S,6R,6?R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6?-[(2S)-butan-2-yl]-19,19b-dihydroxy-5?,6,7,18-tetramethyl-16-oxo-5?,6,6?,9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2?-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Avermectin B1a, delta-8,9 isomer","C47H70O14","CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O","InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Escherichia coli (as organism)","WP2","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","single chemical entity","Component is a metabolite of the substance","[8,9-Z]-isomer of avermectin B1a","","","{(2aZ,4Z,5?S,6R,6?R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6?-[(2S)-butan-2-yl]-19,19b-dihydroxy-5?,6,7,18-tetramethyl-16-oxo-5?,6,6?,9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2?-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Avermectin B1a, delta-8,9 isomer","C47H70O14","CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O","InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Escherichia coli (as organism)","WP2","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","single chemical entity","Component is a metabolite of the substance","[8,9-Z]-isomer of avermectin B1a","","","{(2aZ,4Z,5?S,6R,6?R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6?-[(2S)-butan-2-yl]-19,19b-dihydroxy-5?,6,7,18-tetramethyl-16-oxo-5?,6,6?,9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2?-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Avermectin B1a, delta-8,9 isomer","C47H70O14","CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O","InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Escherichia coli (as organism)","WP2 uvr A pKM 101","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","single chemical entity","Component is a metabolite of the substance","[8,9-Z]-isomer of avermectin B1a","","","{(2aZ,4Z,5?S,6R,6?R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6?-[(2S)-butan-2-yl]-19,19b-dihydroxy-5?,6,7,18-tetramethyl-16-oxo-5?,6,6?,9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2?-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Avermectin B1a, delta-8,9 isomer","C47H70O14","CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O","InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","single chemical entity","Component is a metabolite of the substance","[8,9-Z]-isomer of avermectin B1a","","","{(2aZ,4Z,5?S,6R,6?R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6?-[(2S)-butan-2-yl]-19,19b-dihydroxy-5?,6,7,18-tetramethyl-16-oxo-5?,6,6?,9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2?-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Avermectin B1a, delta-8,9 isomer","C47H70O14","CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O","InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Escherichia coli (as organism)","WP2 uvr A pKM 101","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","single chemical entity","Component is a metabolite of the substance","[8,9-Z]-isomer of avermectin B1a","","","{(2aZ,4Z,5?S,6R,6?R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6?-[(2S)-butan-2-yl]-19,19b-dihydroxy-5?,6,7,18-tetramethyl-16-oxo-5?,6,6?,9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2?-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Avermectin B1a, delta-8,9 isomer","C47H70O14","CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O","InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 97","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","single chemical entity","Component is a metabolite of the substance","[8,9-Z]-isomer of avermectin B1a","","","{(2aZ,4Z,5?S,6R,6?R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6?-[(2S)-butan-2-yl]-19,19b-dihydroxy-5?,6,7,18-tetramethyl-16-oxo-5?,6,6?,9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2?-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Avermectin B1a, delta-8,9 isomer","C47H70O14","CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O","InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","single chemical entity","Component is a metabolite of the substance","[8,9-Z]-isomer of avermectin B1a","","","{(2aZ,4Z,5?S,6R,6?R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6?-[(2S)-butan-2-yl]-19,19b-dihydroxy-5?,6,7,18-tetramethyl-16-oxo-5?,6,6?,9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2?-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Avermectin B1a, delta-8,9 isomer","C47H70O14","CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O","InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","single chemical entity","Component is a metabolite of the substance","[8,9-Z]-isomer of avermectin B1a","","","{(2aZ,4Z,5?S,6R,6?R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6?-[(2S)-butan-2-yl]-19,19b-dihydroxy-5?,6,7,18-tetramethyl-16-oxo-5?,6,6?,9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2?-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Avermectin B1a, delta-8,9 isomer","C47H70O14","CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O","InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","mixture or formulation","Component is identical to the substance","Abamectin","","71751-41-2","(9Z,13Z,15Z)-6'-(butan-2-yl)-19,21b-dihydroxy-5',10,12,20-tetramethyl-1-oxo-3,4,5',6',8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2'-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside","Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)","C49H74O14","CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C","InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-","organic","representative compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","mixture or formulation","Component is identical to the substance","Abamectin","","71751-41-2","(9Z,13Z,15Z)-6'-(butan-2-yl)-19,21b-dihydroxy-5',10,12,20-tetramethyl-1-oxo-3,4,5',6',8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2'-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside","Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)","C49H74O14","CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C","InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-","organic","representative compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","mixture or formulation","Component is identical to the substance","Abamectin","","71751-41-2","(9Z,13Z,15Z)-6'-(butan-2-yl)-19,21b-dihydroxy-5',10,12,20-tetramethyl-1-oxo-3,4,5',6',8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2'-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside","Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)","C49H74O14","CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C","InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-","organic","representative compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","mixture or formulation","Component is identical to the substance","Abamectin","","71751-41-2","(9Z,13Z,15Z)-6'-(butan-2-yl)-19,21b-dihydroxy-5',10,12,20-tetramethyl-1-oxo-3,4,5',6',8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2'-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside","Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)","C49H74O14","CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C","InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-","organic","representative compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","mixture or formulation","Component is identical to the substance","Abamectin","","71751-41-2","(9Z,13Z,15Z)-6'-(butan-2-yl)-19,21b-dihydroxy-5',10,12,20-tetramethyl-1-oxo-3,4,5',6',8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2'-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside","Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)","C49H74O14","CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C","InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-","organic","representative compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 102","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","mixture or formulation","Component is identical to the substance","Abamectin","","71751-41-2","(9Z,13Z,15Z)-6'-(butan-2-yl)-19,21b-dihydroxy-5',10,12,20-tetramethyl-1-oxo-3,4,5',6',8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2'-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside","Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)","C49H74O14","CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C","InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-","organic","representative compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","mixture or formulation","Component is identical to the substance","Abamectin","","71751-41-2","(9Z,13Z,15Z)-6'-(butan-2-yl)-19,21b-dihydroxy-5',10,12,20-tetramethyl-1-oxo-3,4,5',6',8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2'-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside","Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)","C49H74O14","CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C","InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-","organic","representative compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 102","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","mixture or formulation","Component is identical to the substance","Abamectin","","71751-41-2","(9Z,13Z,15Z)-6'-(butan-2-yl)-19,21b-dihydroxy-5',10,12,20-tetramethyl-1-oxo-3,4,5',6',8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2'-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside","Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)","C49H74O14","CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C","InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-","organic","representative compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","mixture or formulation","Component is identical to the substance","Abamectin","","71751-41-2","(9Z,13Z,15Z)-6'-(butan-2-yl)-19,21b-dihydroxy-5',10,12,20-tetramethyl-1-oxo-3,4,5',6',8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2'-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside","Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)","C49H74O14","CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C","InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-","organic","representative compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","mixture or formulation","Component is identical to the substance","Abamectin","","71751-41-2","(9Z,13Z,15Z)-6'-(butan-2-yl)-19,21b-dihydroxy-5',10,12,20-tetramethyl-1-oxo-3,4,5',6',8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2'-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside","Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)","C49H74O14","CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C","InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-","organic","representative compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","mixture or formulation","Component is identical to the substance","Abamectin","","71751-41-2","(9Z,13Z,15Z)-6'-(butan-2-yl)-19,21b-dihydroxy-5',10,12,20-tetramethyl-1-oxo-3,4,5',6',8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2'-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside","Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)","C49H74O14","CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C","InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-","organic","representative compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","mixture or formulation","Component is identical to the substance","Abamectin","","71751-41-2","(9Z,13Z,15Z)-6'-(butan-2-yl)-19,21b-dihydroxy-5',10,12,20-tetramethyl-1-oxo-3,4,5',6',8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2'-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside","Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)","C49H74O14","CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C","InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-","organic","representative compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","single chemical entity","Component is a metabolite of the substance","[8,9-Z]-isomer of avermectin B1a","","","{(2aZ,4Z,5'S,6R,6'R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6'-[(2S)-butan-2-yl]-19,19b-dihydroxy-5',6,7,18-tetramethyl-16-oxo-5',6,6',9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2'-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Avermectin B1a, delta-8,9 isomer","C47H70O14","CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O","InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","single chemical entity","Component is a metabolite of the substance","[8,9-Z]-isomer of avermectin B1a","","","{(2aZ,4Z,5'S,6R,6'R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6'-[(2S)-butan-2-yl]-19,19b-dihydroxy-5',6,7,18-tetramethyl-16-oxo-5',6,6',9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2'-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Avermectin B1a, delta-8,9 isomer","C47H70O14","CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O","InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","single chemical entity","Component is a metabolite of the substance","[8,9-Z]-isomer of avermectin B1a","","","{(2aZ,4Z,5'S,6R,6'R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6'-[(2S)-butan-2-yl]-19,19b-dihydroxy-5',6,7,18-tetramethyl-16-oxo-5',6,6',9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2'-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Avermectin B1a, delta-8,9 isomer","C47H70O14","CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O","InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 97","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","single chemical entity","Component is a metabolite of the substance","[8,9-Z]-isomer of avermectin B1a","","","{(2aZ,4Z,5'S,6R,6'R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6'-[(2S)-butan-2-yl]-19,19b-dihydroxy-5',6,7,18-tetramethyl-16-oxo-5',6,6',9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2'-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Avermectin B1a, delta-8,9 isomer","C47H70O14","CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O","InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","single chemical entity","Component is a metabolite of the substance","[8,9-Z]-isomer of avermectin B1a","","","{(2aZ,4Z,5'S,6R,6'R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6'-[(2S)-butan-2-yl]-19,19b-dihydroxy-5',6,7,18-tetramethyl-16-oxo-5',6,6',9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2'-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Avermectin B1a, delta-8,9 isomer","C47H70O14","CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O","InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","single chemical entity","Component is a metabolite of the substance","[8,9-Z]-isomer of avermectin B1a","","","{(2aZ,4Z,5'S,6R,6'R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6'-[(2S)-butan-2-yl]-19,19b-dihydroxy-5',6,7,18-tetramethyl-16-oxo-5',6,6',9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2'-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Avermectin B1a, delta-8,9 isomer","C47H70O14","CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O","InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Escherichia coli (as organism)","WP2","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","single chemical entity","Component is a metabolite of the substance","[8,9-Z]-isomer of avermectin B1a","","","{(2aZ,4Z,5'S,6R,6'R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6'-[(2S)-butan-2-yl]-19,19b-dihydroxy-5',6,7,18-tetramethyl-16-oxo-5',6,6',9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2'-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Avermectin B1a, delta-8,9 isomer","C47H70O14","CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O","InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Escherichia coli (as organism)","WP2","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","single chemical entity","Component is a metabolite of the substance","[8,9-Z]-isomer of avermectin B1a","","","{(2aZ,4Z,5'S,6R,6'R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6'-[(2S)-butan-2-yl]-19,19b-dihydroxy-5',6,7,18-tetramethyl-16-oxo-5',6,6',9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2'-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Avermectin B1a, delta-8,9 isomer","C47H70O14","CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O","InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Escherichia coli (as organism)","WP2 uvr A pKM 101","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","single chemical entity","Component is a metabolite of the substance","[8,9-Z]-isomer of avermectin B1a","","","{(2aZ,4Z,5'S,6R,6'R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6'-[(2S)-butan-2-yl]-19,19b-dihydroxy-5',6,7,18-tetramethyl-16-oxo-5',6,6',9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2'-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Avermectin B1a, delta-8,9 isomer","C47H70O14","CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O","InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","single chemical entity","Component is a metabolite of the substance","[8,9-Z]-isomer of avermectin B1a","","","{(2aZ,4Z,5'S,6R,6'R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6'-[(2S)-butan-2-yl]-19,19b-dihydroxy-5',6,7,18-tetramethyl-16-oxo-5',6,6',9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2'-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Avermectin B1a, delta-8,9 isomer","C47H70O14","CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O","InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Escherichia coli (as organism)","WP2 uvr A pKM 101","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","single chemical entity","Component is a metabolite of the substance","[8,9-Z]-isomer of avermectin B1a","","","{(2aZ,4Z,5'S,6R,6'R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6'-[(2S)-butan-2-yl]-19,19b-dihydroxy-5',6,7,18-tetramethyl-16-oxo-5',6,6',9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2'-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Avermectin B1a, delta-8,9 isomer","C47H70O14","CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O","InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 97","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","single chemical entity","Component is a metabolite of the substance","[8,9-Z]-isomer of avermectin B1a","","","{(2aZ,4Z,5'S,6R,6'R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6'-[(2S)-butan-2-yl]-19,19b-dihydroxy-5',6,7,18-tetramethyl-16-oxo-5',6,6',9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2'-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Avermectin B1a, delta-8,9 isomer","C47H70O14","CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O","InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","single chemical entity","Component is a metabolite of the substance","[8,9-Z]-isomer of avermectin B1a","","","{(2aZ,4Z,5'S,6R,6'R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6'-[(2S)-butan-2-yl]-19,19b-dihydroxy-5',6,7,18-tetramethyl-16-oxo-5',6,6',9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2'-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Avermectin B1a, delta-8,9 isomer","C47H70O14","CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O","InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","single chemical entity","Component is a metabolite of the substance","[8,9-Z]-isomer of avermectin B1a","","","{(2aZ,4Z,5'S,6R,6'R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6'-[(2S)-butan-2-yl]-19,19b-dihydroxy-5',6,7,18-tetramethyl-16-oxo-5',6,6',9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2'-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Avermectin B1a, delta-8,9 isomer","C47H70O14","CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O","InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" "Acequinocyl","","57960-19-7","single chemical entity","Component is identical to the substance","Acequinocyl","","57960-19-7","3-dodecyl-1,4-dioxo-1,4-dihydronaphthalen-2-yl acetate","Acequinocyl","C24H32O4","CC(=O)OC2=C(CCCCCCCCCCCC)C(=O)c1ccccc1C2=O","InChI=1S/C24H32O4/c1-3-4-5-6-7-8-9-10-11-12-17-21-22(26)19-15-13-14-16-20(19)23(27)24(21)28-18(2)25/h13-16H,3-12,17H2,1-2H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Acequinocyl (Revised version of September 2007)","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl.","41396","2013","doi:10.2903/j.efsa.2013.3212" "Acequinocyl","","57960-19-7","single chemical entity","Component is identical to the substance","Acequinocyl","","57960-19-7","3-dodecyl-1,4-dioxo-1,4-dihydronaphthalen-2-yl acetate","Acequinocyl","C24H32O4","CC(=O)OC2=C(CCCCCCCCCCCC)C(=O)c1ccccc1C2=O","InChI=1S/C24H32O4/c1-3-4-5-6-7-8-9-10-11-12-17-21-22(26)19-15-13-14-16-20(19)23(27)24(21)28-18(2)25/h13-16H,3-12,17H2,1-2H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Acequinocyl (Revised version of September 2007)","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl.","41396","2013","doi:10.2903/j.efsa.2013.3212" "Acequinocyl","","57960-19-7","single chemical entity","Component is identical to the substance","Acequinocyl","","57960-19-7","3-dodecyl-1,4-dioxo-1,4-dihydronaphthalen-2-yl acetate","Acequinocyl","C24H32O4","CC(=O)OC2=C(CCCCCCCCCCCC)C(=O)c1ccccc1C2=O","InChI=1S/C24H32O4/c1-3-4-5-6-7-8-9-10-11-12-17-21-22(26)19-15-13-14-16-20(19)23(27)24(21)28-18(2)25/h13-16H,3-12,17H2,1-2H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Acequinocyl (Revised version of September 2007)","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl.","41396","2013","doi:10.2903/j.efsa.2013.3212" @@ -1497,41 +1497,41 @@ hydroxychromen-2-one","Bromadiolone","C30H23BrO4","C1=CC=C(C=C1)C(CC(C2=CC=C(C=C "L-ascorbic acid","200-066-2","50-81-7","single chemical entity","Component is identical to the substance","L-ascorbic acid","200-066-2","50-81-7","(2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one","L-ascorbic acid","C6H8O6","C(C(C1C(=C(C(=O)O1)O)O)O)O","InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","sister chromatid exchange assay in mammalian cells","in vivo","No guideline available","Not reported","Not applicable","Acceptable","Hamster (as animal)","Not reported","","No data","Not reported","","","no data","not applicable","Negative","","","RMS: The Netherlands","L-ascorbic acid","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance L-ascorbic acid","41389","2013","doi: 10.2903/j.efsa.2013.3197" "L-ascorbic acid","200-066-2","50-81-7","single chemical entity","Component is identical to the substance","L-ascorbic acid","200-066-2","50-81-7","(2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one","L-ascorbic acid","C6H8O6","C(C(C1C(=C(C(=O)O1)O)O)O)O","InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","Equivalent or similar to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No data","Acceptable","House mouse (as animal)","CD-1","","No data","Not reported","","","no data","not applicable","Negative","","","RMS: The Netherlands","L-ascorbic acid","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance L-ascorbic acid","41389","2013","doi: 10.2903/j.efsa.2013.3197" "L-ascorbic acid","200-066-2","50-81-7","single chemical entity","Component is identical to the substance","L-ascorbic acid","200-066-2","50-81-7","(2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one","L-ascorbic acid","C6H8O6","C(C(C1C(=C(C(=O)O1)O)O)O)O","InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","Equivalent or similar to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No data","Acceptable","House mouse (as animal)","B6C3F1","","No data","Not reported","","","no data","not applicable","Negative","","","RMS: The Netherlands","L-ascorbic acid","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance L-ascorbic acid","41389","2013","doi: 10.2903/j.efsa.2013.3197" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1538","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1538","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1538","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1538","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1538","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1538","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","Equivalent or similar to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","Yes","Acceptable","House mouse (as animal)","lymphoma L5178Y cells","","","Not reported","","","yes, concurrent vehicle","with","Negative","no information","","RMS: Germany","Azadirachtin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","Equivalent or similar to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","Yes","Acceptable","House mouse (as animal)","lymphoma L5178Y cells","","","Not reported","","","yes, concurrent vehicle","with","Negative","no information","","RMS: Germany","Azadirachtin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","ICR","10","Male/Female","oral: unspecified","48","h","yes, concurrent vehicle","not applicable","Negative","","no evidence","RMS: Germany","Azadirachtin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","ICR","10","Male/Female","oral: unspecified","72","h","yes, concurrent vehicle","not applicable","Negative","","no evidence","RMS: Germany","Azadirachtin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","ICR","10","Male/Female","oral: unspecified","24","h","yes, concurrent vehicle","not applicable","Negative","","no evidence","RMS: Germany","Azadirachtin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1538","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1538","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1538","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1538","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1538","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1538","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","Equivalent or similar to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","Yes","Acceptable","House mouse (as animal)","lymphoma L5178Y cells","","","Not reported","","","yes, concurrent vehicle","with","Negative","no information","","RMS: Germany","Azadirachtin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","Equivalent or similar to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","Yes","Acceptable","House mouse (as animal)","lymphoma L5178Y cells","","","Not reported","","","yes, concurrent vehicle","with","Negative","no information","","RMS: Germany","Azadirachtin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","ICR","10","Male/Female","oral: unspecified","48","h","yes, concurrent vehicle","not applicable","Negative","","no evidence","RMS: Germany","Azadirachtin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","ICR","10","Male/Female","oral: unspecified","72","h","yes, concurrent vehicle","not applicable","Negative","","no evidence","RMS: Germany","Azadirachtin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","ICR","10","Male/Female","oral: unspecified","24","h","yes, concurrent vehicle","not applicable","Negative","","no evidence","RMS: Germany","Azadirachtin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" "Benfluralin","217-465-2","1861-40-1","single chemical entity","Component is identical to the substance","Benfluralin","217-465-2","1861-40-1","N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline","Benfluralin","C13H16F3N3O4","CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]","InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes","without","Negative","","","RMS: Belgium","Benfluralin","2006","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin","39657","2008","doi:10.2903/j.efsa.2008.127r" "Benfluralin","217-465-2","1861-40-1","single chemical entity","Component is identical to the substance","Benfluralin","217-465-2","1861-40-1","N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline","Benfluralin","C13H16F3N3O4","CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]","InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes","without","Negative","","","RMS: Belgium","Benfluralin","2006","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin","39657","2008","doi:10.2903/j.efsa.2008.127r" "Benfluralin","217-465-2","1861-40-1","single chemical entity","Component is identical to the substance","Benfluralin","217-465-2","1861-40-1","N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline","Benfluralin","C13H16F3N3O4","CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]","InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes","with","Negative","","","RMS: Belgium","Benfluralin","2006","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin","39657","2008","doi:10.2903/j.efsa.2008.127r" @@ -2333,20 +2333,20 @@ hydroxychromen-2-one","Bromadiolone","C30H23BrO4","C1=CC=C(C=C1)C(CC(C2=CC=C(C=C "Chlorsulfuron","265-268-5","64902-72-3","single chemical entity","Component is a metabolite of the substance","2-chlorobenzenesulfonamide","230-156-7","6961-82-6","2-chlorobenzenesulfonamide","Not in list","C6H6ClNO2S","C1=CC=C(C(=C1)S(=O)(=O)N)Cl","InChI=1S/C6H6ClNO2S/c7-5-3-1-2-4-6(5)11(8,9)10/h1-4H,(H2,8,9,10)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Chlorsulfuron","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron","39878","2009","doi:10.2903/j.efsa.2009.201r" "Chlorsulfuron","265-268-5","64902-72-3","single chemical entity","Component is a metabolite of the substance","2-chlorobenzenesulfonamide","230-156-7","6961-82-6","2-chlorobenzenesulfonamide","Not in list","C6H6ClNO2S","C1=CC=C(C(=C1)S(=O)(=O)N)Cl","InChI=1S/C6H6ClNO2S/c7-5-3-1-2-4-6(5)11(8,9)10/h1-4H,(H2,8,9,10)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Chlorsulfuron","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron","39878","2009","doi:10.2903/j.efsa.2009.201r" "Chlorsulfuron","265-268-5","64902-72-3","single chemical entity","Component is a metabolite of the substance","2-chlorobenzenesulfonamide","230-156-7","6961-82-6","2-chlorobenzenesulfonamide","Not in list","C6H6ClNO2S","C1=CC=C(C(=C1)S(=O)(=O)N)Cl","InChI=1S/C6H6ClNO2S/c7-5-3-1-2-4-6(5)11(8,9)10/h1-4H,(H2,8,9,10)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Chlorsulfuron","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron","39878","2009","doi:10.2903/j.efsa.2009.201r" -"Chlorsulfuron","265-268-5","64902-72-3","single chemical entity","Component is a metabolite of the substance","N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide","","","N?-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid","Not in list","C9H10ClN5O4S","O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl","InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Chlorsulfuron","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron","39878","2009","doi:10.2903/j.efsa.2009.201r" -"Chlorsulfuron","265-268-5","64902-72-3","single chemical entity","Component is a metabolite of the substance","N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide","","","N?-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid","Not in list","C9H10ClN5O4S","O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl","InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Chlorsulfuron","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron","39878","2009","doi:10.2903/j.efsa.2009.201r" -"Chlorsulfuron","265-268-5","64902-72-3","single chemical entity","Component is a metabolite of the substance","N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide","","","N?-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid","Not in list","C9H10ClN5O4S","O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl","InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Chlorsulfuron","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron","39878","2009","doi:10.2903/j.efsa.2009.201r" -"Chlorsulfuron","265-268-5","64902-72-3","single chemical entity","Component is a metabolite of the substance","N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide","","","N?-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid","Not in list","C9H10ClN5O4S","O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl","InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Chlorsulfuron","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron","39878","2009","doi:10.2903/j.efsa.2009.201r" -"Chlorsulfuron","265-268-5","64902-72-3","single chemical entity","Component is a metabolite of the substance","N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide","","","N?-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid","Not in list","C9H10ClN5O4S","O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl","InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Chlorsulfuron","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron","39878","2009","doi:10.2903/j.efsa.2009.201r" -"Chlorsulfuron","265-268-5","64902-72-3","single chemical entity","Component is a metabolite of the substance","N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide","","","N?-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid","Not in list","C9H10ClN5O4S","O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl","InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Chlorsulfuron","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron","39878","2009","doi:10.2903/j.efsa.2009.201r" -"Chlorsulfuron","265-268-5","64902-72-3","single chemical entity","Component is a metabolite of the substance","N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide","","","N?-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid","Not in list","C9H10ClN5O4S","O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl","InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Chlorsulfuron","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron","39878","2009","doi:10.2903/j.efsa.2009.201r" -"Chlorsulfuron","265-268-5","64902-72-3","single chemical entity","Component is a metabolite of the substance","N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide","","","N?-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid","Not in list","C9H10ClN5O4S","O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl","InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Chlorsulfuron","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron","39878","2009","doi:10.2903/j.efsa.2009.201r" -"Chlorsulfuron","265-268-5","64902-72-3","single chemical entity","Component is a metabolite of the substance","N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide","","","N?-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid","Not in list","C9H10ClN5O4S","O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl","InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Chlorsulfuron","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron","39878","2009","doi:10.2903/j.efsa.2009.201r" -"Chlorsulfuron","265-268-5","64902-72-3","single chemical entity","Component is a metabolite of the substance","N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide","","","N?-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid","Not in list","C9H10ClN5O4S","O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl","InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Chlorsulfuron","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron","39878","2009","doi:10.2903/j.efsa.2009.201r" -"Chlorsulfuron","265-268-5","64902-72-3","single chemical entity","Component is a metabolite of the substance","N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide","","","N?-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid","Not in list","C9H10ClN5O4S","O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl","InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Chlorsulfuron","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron","39878","2009","doi:10.2903/j.efsa.2009.201r" -"Chlorsulfuron","265-268-5","64902-72-3","single chemical entity","Component is a metabolite of the substance","N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide","","","N?-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid","Not in list","C9H10ClN5O4S","O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl","InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Chlorsulfuron","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron","39878","2009","doi:10.2903/j.efsa.2009.201r" -"Chlorsulfuron","265-268-5","64902-72-3","single chemical entity","Component is a metabolite of the substance","N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide","","","N?-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid","Not in list","C9H10ClN5O4S","O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl","InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Chlorsulfuron","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron","39878","2009","doi:10.2903/j.efsa.2009.201r" -"Chlorsulfuron","265-268-5","64902-72-3","single chemical entity","Component is a metabolite of the substance","N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide","","","N?-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid","Not in list","C9H10ClN5O4S","O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl","InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Chlorsulfuron","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron","39878","2009","doi:10.2903/j.efsa.2009.201r" +"Chlorsulfuron","265-268-5","64902-72-3","single chemical entity","Component is a metabolite of the substance","N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide","","","N'-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid","Not in list","C9H10ClN5O4S","O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl","InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Chlorsulfuron","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron","39878","2009","doi:10.2903/j.efsa.2009.201r" +"Chlorsulfuron","265-268-5","64902-72-3","single chemical entity","Component is a metabolite of the substance","N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide","","","N'-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid","Not in list","C9H10ClN5O4S","O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl","InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Chlorsulfuron","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron","39878","2009","doi:10.2903/j.efsa.2009.201r" +"Chlorsulfuron","265-268-5","64902-72-3","single chemical entity","Component is a metabolite of the substance","N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide","","","N'-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid","Not in list","C9H10ClN5O4S","O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl","InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Chlorsulfuron","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron","39878","2009","doi:10.2903/j.efsa.2009.201r" +"Chlorsulfuron","265-268-5","64902-72-3","single chemical entity","Component is a metabolite of the substance","N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide","","","N'-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid","Not in list","C9H10ClN5O4S","O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl","InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Chlorsulfuron","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron","39878","2009","doi:10.2903/j.efsa.2009.201r" +"Chlorsulfuron","265-268-5","64902-72-3","single chemical entity","Component is a metabolite of the substance","N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide","","","N'-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid","Not in list","C9H10ClN5O4S","O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl","InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Chlorsulfuron","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron","39878","2009","doi:10.2903/j.efsa.2009.201r" +"Chlorsulfuron","265-268-5","64902-72-3","single chemical entity","Component is a metabolite of the substance","N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide","","","N'-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid","Not in list","C9H10ClN5O4S","O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl","InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Chlorsulfuron","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron","39878","2009","doi:10.2903/j.efsa.2009.201r" +"Chlorsulfuron","265-268-5","64902-72-3","single chemical entity","Component is a metabolite of the substance","N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide","","","N'-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid","Not in list","C9H10ClN5O4S","O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl","InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Chlorsulfuron","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron","39878","2009","doi:10.2903/j.efsa.2009.201r" +"Chlorsulfuron","265-268-5","64902-72-3","single chemical entity","Component is a metabolite of the substance","N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide","","","N'-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid","Not in list","C9H10ClN5O4S","O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl","InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Chlorsulfuron","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron","39878","2009","doi:10.2903/j.efsa.2009.201r" +"Chlorsulfuron","265-268-5","64902-72-3","single chemical entity","Component is a metabolite of the substance","N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide","","","N'-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid","Not in list","C9H10ClN5O4S","O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl","InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Chlorsulfuron","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron","39878","2009","doi:10.2903/j.efsa.2009.201r" +"Chlorsulfuron","265-268-5","64902-72-3","single chemical entity","Component is a metabolite of the substance","N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide","","","N'-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid","Not in list","C9H10ClN5O4S","O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl","InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Chlorsulfuron","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron","39878","2009","doi:10.2903/j.efsa.2009.201r" +"Chlorsulfuron","265-268-5","64902-72-3","single chemical entity","Component is a metabolite of the substance","N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide","","","N'-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid","Not in list","C9H10ClN5O4S","O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl","InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Chlorsulfuron","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron","39878","2009","doi:10.2903/j.efsa.2009.201r" +"Chlorsulfuron","265-268-5","64902-72-3","single chemical entity","Component is a metabolite of the substance","N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide","","","N'-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid","Not in list","C9H10ClN5O4S","O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl","InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Chlorsulfuron","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron","39878","2009","doi:10.2903/j.efsa.2009.201r" +"Chlorsulfuron","265-268-5","64902-72-3","single chemical entity","Component is a metabolite of the substance","N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide","","","N'-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid","Not in list","C9H10ClN5O4S","O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl","InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Chlorsulfuron","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron","39878","2009","doi:10.2903/j.efsa.2009.201r" +"Chlorsulfuron","265-268-5","64902-72-3","single chemical entity","Component is a metabolite of the substance","N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide","","","N'-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid","Not in list","C9H10ClN5O4S","O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl","InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Chlorsulfuron","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron","39878","2009","doi:10.2903/j.efsa.2009.201r" "Clopyralid","216-935-4","1702-17-6","single chemical entity","Component is identical to the substance","Clopyralid","216-935-4","1702-17-6","3,6-dichloropyridine-2-carboxylic acid","Clopyralid","C6H3Cl2NO2","C1=CC(=NC(=C1Cl)C(=O)O)Cl","InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Clopyralid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid","38740","2006","doi: 10.2903/j.efsa.2006.50r" "Clopyralid","216-935-4","1702-17-6","single chemical entity","Component is identical to the substance","Clopyralid","216-935-4","1702-17-6","3,6-dichloropyridine-2-carboxylic acid","Clopyralid","C6H3Cl2NO2","C1=CC(=NC(=C1Cl)C(=O)O)Cl","InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Clopyralid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid","38740","2006","doi: 10.2903/j.efsa.2006.50r" "Clopyralid","216-935-4","1702-17-6","single chemical entity","Component is identical to the substance","Clopyralid","216-935-4","1702-17-6","3,6-dichloropyridine-2-carboxylic acid","Clopyralid","C6H3Cl2NO2","C1=CC(=NC(=C1Cl)C(=O)O)Cl","InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1538","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Clopyralid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid","38740","2006","doi: 10.2903/j.efsa.2006.50r" @@ -2674,28 +2674,28 @@ hydroxychromen-2-one","Bromadiolone","C30H23BrO4","C1=CC=C(C=C1)C(CC(C2=CC=C(C=C "Cymoxanil","261-043-0","57966-95-7","single chemical entity","Component is identical to the substance","Cymoxanil","261-043-0","57966-95-7","(1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide","Cymoxanil","C7H10N4O3","CCNC(=O)NC(=O)/C(=N/OC)/C#N","InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+","organic","representative isomer","PubChem isomeric SMILES","PubChem InChI","DNA damage and/or repair","unscheduled DNA synthesis","in vivo","Equivalent or similar to","OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)","Yes","Acceptable","Rat (as animal)","Crj:CD(SD)","5","Male","oral: gavage","16","h","yes, concurrent vehicle","not applicable","Negative","","","RMS: Austria","Cymoxanil","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil","39738","2008","doi:10.2903/j.efsa.2008.167r" "Cymoxanil","261-043-0","57966-95-7","single chemical entity","Component is identical to the substance","Cymoxanil","261-043-0","57966-95-7","(1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide","Cymoxanil","C7H10N4O3","CCNC(=O)NC(=O)/C(=N/OC)/C#N","InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+","organic","representative isomer","PubChem isomeric SMILES","PubChem InChI","DNA damage and/or repair","unscheduled DNA synthesis","in vivo","Equivalent or similar to","OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)","Yes","Acceptable","Rat (as animal)","Crj:CD(SD)","5","Male","oral: gavage","16","h","yes, concurrent vehicle","not applicable","Negative","","","RMS: Austria","Cymoxanil","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil","39738","2008","doi:10.2903/j.efsa.2008.167r" "Cymoxanil","261-043-0","57966-95-7","single chemical entity","Component is identical to the substance","Cymoxanil","261-043-0","57966-95-7","(1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide","Cymoxanil","C7H10N4O3","CCNC(=O)NC(=O)/C(=N/OC)/C#N","InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+","organic","representative isomer","PubChem isomeric SMILES","PubChem InChI","DNA damage and/or repair","unscheduled DNA synthesis","in vivo","Equivalent or similar to","OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)","Yes","Acceptable","Rat (as animal)","Crj:CD(SD)","5","Male","oral: gavage","2","h","yes, concurrent vehicle","not applicable","Negative","","","RMS: Austria","Cymoxanil","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil","39738","2008","doi:10.2903/j.efsa.2008.167r" -"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1?,2?-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" -"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1?,2?-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" -"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1?,2?-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" -"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1?,2?-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" -"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1?,2?-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1538","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" -"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1?,2?-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A pKM 101","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" -"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1?,2?-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A pKM 101","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" -"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1?,2?-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" -"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1?,2?-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" -"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1?,2?-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" -"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1?,2?-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1538","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" -"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1?,2?-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" -"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1?,2?-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","House mouse (as animal)","lymphoma L5178Y cells","","","Not reported","","","yes","without","Negative","no information","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" -"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1?,2?-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","House mouse (as animal)","lymphoma L5178Y cells","","","Not reported","","","yes","with","Negative","no information","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" -"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1?,2?-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes","without","Ambiguous","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" -"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1?,2?-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes","with","Ambiguous","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" -"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1?,2?-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","C57BL","10","Male/Female","oral: unspecified","48","h","yes, concurrent vehicle","not applicable","Negative","","direct evidence-cytotoxicity","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" -"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1?,2?-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","C57BL","10","Male/Female","oral: unspecified","24","h","yes, concurrent vehicle","not applicable","Negative","","direct evidence-cytotoxicity","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" -"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1?,2?-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","C57BL","10","Male/Female","oral: unspecified","72","h","yes, concurrent vehicle","not applicable","Negative","","direct evidence-cytotoxicity","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" -"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1?,2?-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","unscheduled DNA synthesis","in vivo","According to","OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)","No","Acceptable","Rat (as animal)","Sprague-Dawley","","Male","oral: unspecified","4","h","yes","not applicable","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" -"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1?,2?-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","unscheduled DNA synthesis","in vivo","According to","OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)","No","Acceptable","Rat (as animal)","Sprague-Dawley","","Male","oral: unspecified","12","h","yes","not applicable","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" -"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1?,2?-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","dominant lethal assay","in vivo","Equivalent or similar to","OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)","Yes","Acceptable","House mouse (as animal)","CD-1","105","Male","oral: gavage","5","D","yes, concurrent vehicle","not applicable","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" +"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" +"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" +"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" +"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" +"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1538","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" +"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A pKM 101","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" +"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A pKM 101","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" +"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" +"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" +"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" +"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1538","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" +"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" +"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","House mouse (as animal)","lymphoma L5178Y cells","","","Not reported","","","yes","without","Negative","no information","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" +"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","House mouse (as animal)","lymphoma L5178Y cells","","","Not reported","","","yes","with","Negative","no information","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" +"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes","without","Ambiguous","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" +"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes","with","Ambiguous","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" +"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","C57BL","10","Male/Female","oral: unspecified","48","h","yes, concurrent vehicle","not applicable","Negative","","direct evidence-cytotoxicity","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" +"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","C57BL","10","Male/Female","oral: unspecified","24","h","yes, concurrent vehicle","not applicable","Negative","","direct evidence-cytotoxicity","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" +"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","C57BL","10","Male/Female","oral: unspecified","72","h","yes, concurrent vehicle","not applicable","Negative","","direct evidence-cytotoxicity","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" +"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","unscheduled DNA synthesis","in vivo","According to","OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)","No","Acceptable","Rat (as animal)","Sprague-Dawley","","Male","oral: unspecified","4","h","yes","not applicable","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" +"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","unscheduled DNA synthesis","in vivo","According to","OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)","No","Acceptable","Rat (as animal)","Sprague-Dawley","","Male","oral: unspecified","12","h","yes","not applicable","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" +"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","dominant lethal assay","in vivo","Equivalent or similar to","OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)","Yes","Acceptable","House mouse (as animal)","CD-1","105","Male","oral: gavage","5","D","yes, concurrent vehicle","not applicable","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" "Diquat","220-433-0","85-00-7","single chemical entity","Component is a metabolite of the substance","1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium","","","1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium","Not in list","C8H9N2O","O=C1NCC[n+]2ccccc12","InChI=1/C8H8N2O/c11-8-7-3-1-2-5-10(7)6-4-9-8/h1-3,5H,4,6H2/p+1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","no data","with","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" "Diquat","220-433-0","85-00-7","single chemical entity","Component is a metabolite of the substance","1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium","","","1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium","Not in list","C8H9N2O","O=C1NCC[n+]2ccccc12","InChI=1/C8H8N2O/c11-8-7-3-1-2-5-10(7)6-4-9-8/h1-3,5H,4,6H2/p+1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","no data","with","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" "Diquat","220-433-0","85-00-7","single chemical entity","Component is a metabolite of the substance","1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium","","","1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium","Not in list","C8H9N2O","O=C1NCC[n+]2ccccc12","InChI=1/C8H8N2O/c11-8-7-3-1-2-5-10(7)6-4-9-8/h1-3,5H,4,6H2/p+1","organic","compound","Other","Other","DNA damage and/or repair","Bacillus subtilis recombination assay","in vitro","No guideline available","Not reported","Not applicable","Acceptable","Bacillus subtilis (as organism)","H17","","","Not reported","","","no data","with","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" @@ -2924,18 +2924,18 @@ hydroxychromen-2-one","Bromadiolone","C30H23BrO4","C1=CC=C(C=C1)C(CC(C2=CC=C(C=C "Cyflufenamid","","180409-60-3","single chemical entity","Component is identical to the substance","Cyflufenamid","","180409-60-3","N-[(cyclopropylmethoxyamino)-[2,3-difluoro-6-(trifluoromethyl)phenyl]methylidene]-2-phenylacetamide","Cyflufenamid: sum of cyflufenamid (Z-isomer) and its E-isomer","C20H17F5N2O2","C1CC1CONC(=NC(=O)CC2=CC=CC=C2)C3=C(C=CC(=C3F)F)C(F)(F)F","InChI=1S/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","CD-1","20","Male/Female","oral: gavage","24","h","yes, concurrent vehicle","not applicable","Negative","","no evidence","RMS: The United Kingdom","Cyflufenamid","2006","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance cyflufenamid","39962","2009","doi:10.2903/j.efsa.2009.258r" "Cyflufenamid","","180409-60-3","single chemical entity","Component is identical to the substance","Cyflufenamid","","180409-60-3","N-[(cyclopropylmethoxyamino)-[2,3-difluoro-6-(trifluoromethyl)phenyl]methylidene]-2-phenylacetamide","Cyflufenamid: sum of cyflufenamid (Z-isomer) and its E-isomer","C20H17F5N2O2","C1CC1CONC(=NC(=O)CC2=CC=CC=C2)C3=C(C=CC(=C3F)F)C(F)(F)F","InChI=1S/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","unscheduled DNA synthesis","in vivo","According to","OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)","No","Acceptable","Rat (as animal)","Sprague-Dawley","4","Male","oral: gavage","2","h","yes, concurrent vehicle","not applicable","Negative","","","RMS: The United Kingdom","Cyflufenamid","2006","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance cyflufenamid","39962","2009","doi:10.2903/j.efsa.2009.258r" "Cyflufenamid","","180409-60-3","single chemical entity","Component is identical to the substance","Cyflufenamid","","180409-60-3","N-[(cyclopropylmethoxyamino)-[2,3-difluoro-6-(trifluoromethyl)phenyl]methylidene]-2-phenylacetamide","Cyflufenamid: sum of cyflufenamid (Z-isomer) and its E-isomer","C20H17F5N2O2","C1CC1CONC(=NC(=O)CC2=CC=CC=C2)C3=C(C=CC(=C3F)F)C(F)(F)F","InChI=1S/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","unscheduled DNA synthesis","in vivo","According to","OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)","No","Acceptable","Rat (as animal)","Sprague-Dawley","4","Male","oral: gavage","14","h","yes, concurrent vehicle","not applicable","Negative","","","RMS: The United Kingdom","Cyflufenamid","2006","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance cyflufenamid","39962","2009","doi:10.2903/j.efsa.2009.258r" -"Cyflufenamid","","180409-60-3","single chemical entity","Component is a metabolite of the substance","N?-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","","","N?-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","Not in list","C12H11F5N2O","N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F","InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes","with","Negative","","","RMS: The United Kingdom","Cyflufenamid","2006","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance cyflufenamid","39962","2009","doi:10.2903/j.efsa.2009.258r" -"Cyflufenamid","","180409-60-3","single chemical entity","Component is a metabolite of the substance","N?-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","","","N?-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","Not in list","C12H11F5N2O","N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F","InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes","with","Negative","","","RMS: The United Kingdom","Cyflufenamid","2006","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance cyflufenamid","39962","2009","doi:10.2903/j.efsa.2009.258r" -"Cyflufenamid","","180409-60-3","single chemical entity","Component is a metabolite of the substance","N?-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","","","N?-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","Not in list","C12H11F5N2O","N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F","InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes","with","Negative","","","RMS: The United Kingdom","Cyflufenamid","2006","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance cyflufenamid","39962","2009","doi:10.2903/j.efsa.2009.258r" -"Cyflufenamid","","180409-60-3","single chemical entity","Component is a metabolite of the substance","N?-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","","","N?-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","Not in list","C12H11F5N2O","N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F","InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes","without","Negative","","","RMS: The United Kingdom","Cyflufenamid","2006","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance cyflufenamid","39962","2009","doi:10.2903/j.efsa.2009.258r" -"Cyflufenamid","","180409-60-3","single chemical entity","Component is a metabolite of the substance","N?-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","","","N?-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","Not in list","C12H11F5N2O","N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F","InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes","with","Negative","","","RMS: The United Kingdom","Cyflufenamid","2006","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance cyflufenamid","39962","2009","doi:10.2903/j.efsa.2009.258r" -"Cyflufenamid","","180409-60-3","single chemical entity","Component is a metabolite of the substance","N?-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","","","N?-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","Not in list","C12H11F5N2O","N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F","InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes","with","Negative","","","RMS: The United Kingdom","Cyflufenamid","2006","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance cyflufenamid","39962","2009","doi:10.2903/j.efsa.2009.258r" -"Cyflufenamid","","180409-60-3","single chemical entity","Component is a metabolite of the substance","N?-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","","","N?-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","Not in list","C12H11F5N2O","N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F","InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","CM891","","","Not reported","","","yes","with","Negative","","","RMS: The United Kingdom","Cyflufenamid","2006","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance cyflufenamid","39962","2009","doi:10.2903/j.efsa.2009.258r" -"Cyflufenamid","","180409-60-3","single chemical entity","Component is a metabolite of the substance","N?-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","","","N?-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","Not in list","C12H11F5N2O","N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F","InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes","without","Negative","","","RMS: The United Kingdom","Cyflufenamid","2006","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance cyflufenamid","39962","2009","doi:10.2903/j.efsa.2009.258r" -"Cyflufenamid","","180409-60-3","single chemical entity","Component is a metabolite of the substance","N?-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","","","N?-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","Not in list","C12H11F5N2O","N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F","InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","CM891","","","Not reported","","","yes","without","Negative","","","RMS: The United Kingdom","Cyflufenamid","2006","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance cyflufenamid","39962","2009","doi:10.2903/j.efsa.2009.258r" -"Cyflufenamid","","180409-60-3","single chemical entity","Component is a metabolite of the substance","N?-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","","","N?-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","Not in list","C12H11F5N2O","N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F","InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes","without","Negative","","","RMS: The United Kingdom","Cyflufenamid","2006","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance cyflufenamid","39962","2009","doi:10.2903/j.efsa.2009.258r" -"Cyflufenamid","","180409-60-3","single chemical entity","Component is a metabolite of the substance","N?-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","","","N?-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","Not in list","C12H11F5N2O","N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F","InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes","without","Negative","","","RMS: The United Kingdom","Cyflufenamid","2006","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance cyflufenamid","39962","2009","doi:10.2903/j.efsa.2009.258r" -"Cyflufenamid","","180409-60-3","single chemical entity","Component is a metabolite of the substance","N?-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","","","N?-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","Not in list","C12H11F5N2O","N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F","InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes","without","Negative","","","RMS: The United Kingdom","Cyflufenamid","2006","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance cyflufenamid","39962","2009","doi:10.2903/j.efsa.2009.258r" +"Cyflufenamid","","180409-60-3","single chemical entity","Component is a metabolite of the substance","N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","","","N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","Not in list","C12H11F5N2O","N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F","InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes","with","Negative","","","RMS: The United Kingdom","Cyflufenamid","2006","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance cyflufenamid","39962","2009","doi:10.2903/j.efsa.2009.258r" +"Cyflufenamid","","180409-60-3","single chemical entity","Component is a metabolite of the substance","N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","","","N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","Not in list","C12H11F5N2O","N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F","InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes","with","Negative","","","RMS: The United Kingdom","Cyflufenamid","2006","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance cyflufenamid","39962","2009","doi:10.2903/j.efsa.2009.258r" +"Cyflufenamid","","180409-60-3","single chemical entity","Component is a metabolite of the substance","N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","","","N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","Not in list","C12H11F5N2O","N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F","InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes","with","Negative","","","RMS: The United Kingdom","Cyflufenamid","2006","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance cyflufenamid","39962","2009","doi:10.2903/j.efsa.2009.258r" +"Cyflufenamid","","180409-60-3","single chemical entity","Component is a metabolite of the substance","N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","","","N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","Not in list","C12H11F5N2O","N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F","InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes","without","Negative","","","RMS: The United Kingdom","Cyflufenamid","2006","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance cyflufenamid","39962","2009","doi:10.2903/j.efsa.2009.258r" +"Cyflufenamid","","180409-60-3","single chemical entity","Component is a metabolite of the substance","N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","","","N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","Not in list","C12H11F5N2O","N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F","InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes","with","Negative","","","RMS: The United Kingdom","Cyflufenamid","2006","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance cyflufenamid","39962","2009","doi:10.2903/j.efsa.2009.258r" +"Cyflufenamid","","180409-60-3","single chemical entity","Component is a metabolite of the substance","N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","","","N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","Not in list","C12H11F5N2O","N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F","InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes","with","Negative","","","RMS: The United Kingdom","Cyflufenamid","2006","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance cyflufenamid","39962","2009","doi:10.2903/j.efsa.2009.258r" +"Cyflufenamid","","180409-60-3","single chemical entity","Component is a metabolite of the substance","N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","","","N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","Not in list","C12H11F5N2O","N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F","InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","CM891","","","Not reported","","","yes","with","Negative","","","RMS: The United Kingdom","Cyflufenamid","2006","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance cyflufenamid","39962","2009","doi:10.2903/j.efsa.2009.258r" +"Cyflufenamid","","180409-60-3","single chemical entity","Component is a metabolite of the substance","N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","","","N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","Not in list","C12H11F5N2O","N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F","InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes","without","Negative","","","RMS: The United Kingdom","Cyflufenamid","2006","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance cyflufenamid","39962","2009","doi:10.2903/j.efsa.2009.258r" +"Cyflufenamid","","180409-60-3","single chemical entity","Component is a metabolite of the substance","N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","","","N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","Not in list","C12H11F5N2O","N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F","InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","CM891","","","Not reported","","","yes","without","Negative","","","RMS: The United Kingdom","Cyflufenamid","2006","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance cyflufenamid","39962","2009","doi:10.2903/j.efsa.2009.258r" +"Cyflufenamid","","180409-60-3","single chemical entity","Component is a metabolite of the substance","N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","","","N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","Not in list","C12H11F5N2O","N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F","InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes","without","Negative","","","RMS: The United Kingdom","Cyflufenamid","2006","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance cyflufenamid","39962","2009","doi:10.2903/j.efsa.2009.258r" +"Cyflufenamid","","180409-60-3","single chemical entity","Component is a metabolite of the substance","N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","","","N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","Not in list","C12H11F5N2O","N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F","InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes","without","Negative","","","RMS: The United Kingdom","Cyflufenamid","2006","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance cyflufenamid","39962","2009","doi:10.2903/j.efsa.2009.258r" +"Cyflufenamid","","180409-60-3","single chemical entity","Component is a metabolite of the substance","N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","","","N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","Not in list","C12H11F5N2O","N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F","InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes","without","Negative","","","RMS: The United Kingdom","Cyflufenamid","2006","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance cyflufenamid","39962","2009","doi:10.2903/j.efsa.2009.258r" "Cyflufenamid","","180409-60-3","single chemical entity","Component is a metabolite of the substance","2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","","","2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","Not in list","C8H5F5N2","Fc1c(C(=N)N)c(ccc1F)C(F)(F)F","InChI=1/C8H5F5N2/c9-4-2-1-3(8(11,12)13)5(6(4)10)7(14)15/h1-2H,(H3,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes","with","Negative","","","RMS: The United Kingdom","Cyflufenamid","2006","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance cyflufenamid","39962","2009","doi:10.2903/j.efsa.2009.258r" "Cyflufenamid","","180409-60-3","single chemical entity","Component is a metabolite of the substance","2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","","","2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","Not in list","C8H5F5N2","Fc1c(C(=N)N)c(ccc1F)C(F)(F)F","InChI=1/C8H5F5N2/c9-4-2-1-3(8(11,12)13)5(6(4)10)7(14)15/h1-2H,(H3,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","CM891","","","Not reported","","","yes","with","Negative","","","RMS: The United Kingdom","Cyflufenamid","2006","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance cyflufenamid","39962","2009","doi:10.2903/j.efsa.2009.258r" "Cyflufenamid","","180409-60-3","single chemical entity","Component is a metabolite of the substance","2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","","","2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","Not in list","C8H5F5N2","Fc1c(C(=N)N)c(ccc1F)C(F)(F)F","InChI=1/C8H5F5N2/c9-4-2-1-3(8(11,12)13)5(6(4)10)7(14)15/h1-2H,(H3,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes","with","Negative","","","RMS: The United Kingdom","Cyflufenamid","2006","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance cyflufenamid","39962","2009","doi:10.2903/j.efsa.2009.258r" @@ -3330,28 +3330,28 @@ hydroxychromen-2-one","Bromadiolone","C30H23BrO4","C1=CC=C(C=C1)C(CC(C2=CC=C(C=C "Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is identical to the substance","Etofenprox","407-980-2","80844-07-1","1-Ethoxy-4-[2-methyl-1-[(3-phenoxyphenyl)methoxy]propan-2-yl]benzene","Etofenprox","C25H28O3","CCOC1=CC=C(C=C1)C(C)(C)COCC2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H28O3/c1-4-27-22-15-13-21(14-16-22)25(2,3)19-26-18-20-9-8-12-24(17-20)28-23-10-6-5-7-11-23/h5-17H,4,18-19H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","CD-1","10","Male/Female","oral: gavage","24","h","yes, concurrent vehicle","not applicable","Negative","","no evidence","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" "Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is identical to the substance","Etofenprox","407-980-2","80844-07-1","1-Ethoxy-4-[2-methyl-1-[(3-phenoxyphenyl)methoxy]propan-2-yl]benzene","Etofenprox","C25H28O3","CCOC1=CC=C(C=C1)C(C)(C)COCC2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H28O3/c1-4-27-22-15-13-21(14-16-22)25(2,3)19-26-18-20-9-8-12-24(17-20)28-23-10-6-5-7-11-23/h5-17H,4,18-19H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","CD-1","10","Male/Female","oral: gavage","48","h","yes, concurrent vehicle","not applicable","Negative","","no evidence","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" "Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is identical to the substance","Etofenprox","407-980-2","80844-07-1","1-Ethoxy-4-[2-methyl-1-[(3-phenoxyphenyl)methoxy]propan-2-yl]benzene","Etofenprox","C25H28O3","CCOC1=CC=C(C=C1)C(C)(C)COCC2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H28O3/c1-4-27-22-15-13-21(14-16-22)25(2,3)19-26-18-20-9-8-12-24(17-20)28-23-10-6-5-7-11-23/h5-17H,4,18-19H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","CD-1","10","Male/Female","oral: gavage","72","h","yes, concurrent vehicle","not applicable","Negative","","no evidence","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" -"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C(c)(c)COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes","with","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" -"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C(c)(c)COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes","without","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" -"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C(c)(c)COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes","with","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" -"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C(c)(c)COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 97","","","Not reported","","","yes","with","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" -"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C(c)(c)COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes","without","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" -"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C(c)(c)COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes","without","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" -"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C(c)(c)COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 102","","","Not reported","","","yes","without","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" -"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C(c)(c)COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes","with","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" -"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C(c)(c)COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes","with","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" -"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C(c)(c)COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 102","","","Not reported","","","yes","with","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" -"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C(c)(c)COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes","without","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" -"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C(c)(c)COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 97","","","Not reported","","","yes","without","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" -"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C(c)(c)COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes","with","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" -"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C(c)(c)COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes","without","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" -"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C(c)(c)COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","other","in vitro","No guideline available","Not reported","Not applicable","Acceptable","Escherichia coli (as organism)","CM871","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" -"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C(c)(c)COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","other","in vitro","No guideline available","Not reported","Not applicable","Acceptable","Escherichia coli (as organism)","CM871","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" -"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C(c)(c)COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","other","in vitro","No guideline available","Not reported","Not applicable","Acceptable","Escherichia coli (as organism)","WP67","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" -"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C(c)(c)COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","other","in vitro","No guideline available","Not reported","Not applicable","Acceptable","Escherichia coli (as organism)","WP67","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" -"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C(c)(c)COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","other","in vitro","No guideline available","Not reported","Not applicable","Acceptable","Escherichia coli (as organism)","WP2","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" -"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C(c)(c)COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","other","in vitro","No guideline available","Not reported","Not applicable","Acceptable","Escherichia coli (as organism)","WP2","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" -"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C(c)(c)COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","Equivalent or similar to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","Yes","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes","without","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" -"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C(c)(c)COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","Equivalent or similar to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","Yes","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes","with","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" +"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C¿¿COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes","with","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" +"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C¿¿COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes","without","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" +"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C¿¿COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes","with","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" +"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C¿¿COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 97","","","Not reported","","","yes","with","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" +"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C¿¿COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes","without","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" +"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C¿¿COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes","without","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" +"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C¿¿COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 102","","","Not reported","","","yes","without","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" +"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C¿¿COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes","with","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" +"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C¿¿COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes","with","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" +"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C¿¿COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 102","","","Not reported","","","yes","with","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" +"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C¿¿COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes","without","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" +"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C¿¿COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 97","","","Not reported","","","yes","without","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" +"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C¿¿COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes","with","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" +"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C¿¿COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes","without","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" +"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C¿¿COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","other","in vitro","No guideline available","Not reported","Not applicable","Acceptable","Escherichia coli (as organism)","CM871","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" +"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C¿¿COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","other","in vitro","No guideline available","Not reported","Not applicable","Acceptable","Escherichia coli (as organism)","CM871","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" +"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C¿¿COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","other","in vitro","No guideline available","Not reported","Not applicable","Acceptable","Escherichia coli (as organism)","WP67","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" +"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C¿¿COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","other","in vitro","No guideline available","Not reported","Not applicable","Acceptable","Escherichia coli (as organism)","WP67","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" +"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C¿¿COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","other","in vitro","No guideline available","Not reported","Not applicable","Acceptable","Escherichia coli (as organism)","WP2","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" +"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C¿¿COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","other","in vitro","No guideline available","Not reported","Not applicable","Acceptable","Escherichia coli (as organism)","WP2","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" +"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C¿¿COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","Equivalent or similar to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","Yes","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes","without","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" +"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C¿¿COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","Equivalent or similar to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","Yes","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes","with","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" "Dimoxystrobin","","149961-52-4","single chemical entity","Component is identical to the substance","Dimoxystrobin","","149961-52-4","(2Z)-2-[2-[(2,5-dimethylphenoxy)methyl]phenyl]-2-methoxyimino-N-methylacetamide","Dimoxystrobin","C19H22N2O3","CC1=CC(=C(C=C1)C)OCC2=CC=CC=C2C(=NOC)C(=O)NC","InChI=1S/C19H22N2O3/c1-13-9-10-14(2)17(11-13)24-12-15-7-5-6-8-16(15)18(21-23-4)19(22)20-3/h5-11H,12H2,1-4H3,(H,20,22)/b21-18-","organic","compound","PubChem isomeric SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Dimoxystrobin","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin","38595","2005","doi:10.2903/j.efsa.2005.46r" "Dimoxystrobin","","149961-52-4","single chemical entity","Component is identical to the substance","Dimoxystrobin","","149961-52-4","(2Z)-2-[2-[(2,5-dimethylphenoxy)methyl]phenyl]-2-methoxyimino-N-methylacetamide","Dimoxystrobin","C19H22N2O3","CC1=CC(=C(C=C1)C)OCC2=CC=CC=C2C(=NOC)C(=O)NC","InChI=1S/C19H22N2O3/c1-13-9-10-14(2)17(11-13)24-12-15-7-5-6-8-16(15)18(21-23-4)19(22)20-3/h5-11H,12H2,1-4H3,(H,20,22)/b21-18-","organic","compound","PubChem isomeric SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Dimoxystrobin","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin","38595","2005","doi:10.2903/j.efsa.2005.46r" "Dimoxystrobin","","149961-52-4","single chemical entity","Component is identical to the substance","Dimoxystrobin","","149961-52-4","(2Z)-2-[2-[(2,5-dimethylphenoxy)methyl]phenyl]-2-methoxyimino-N-methylacetamide","Dimoxystrobin","C19H22N2O3","CC1=CC(=C(C=C1)C)OCC2=CC=CC=C2C(=NOC)C(=O)NC","InChI=1S/C19H22N2O3/c1-13-9-10-14(2)17(11-13)24-12-15-7-5-6-8-16(15)18(21-23-4)19(22)20-3/h5-11H,12H2,1-4H3,(H,20,22)/b21-18-","organic","compound","PubChem isomeric SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Dimoxystrobin","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin","38595","2005","doi:10.2903/j.efsa.2005.46r" @@ -3799,7 +3799,7 @@ hydroxychromen-2-one","Bromadiolone","C30H23BrO4","C1=CC=C(C=C1)C(CC(C2=CC=C(C=C "Bispyribac-sodium","","125401-92-5","single chemical entity","Component is a metabolite of the substance","benzoic acid, 2-[(4,6-dimethoxy-2-pyrimidinyl)oxy]-6-[(4-hydroxy-6-methoxy-2-pyrimidinyl)oxy],sodium salt","","","sodium 2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-[(4-hydroxy-6-methoxypyrimidin-2-yl)oxy]benzoate","Not in list","C18H15N4NaO8","[Na+].Oc1nc(nc(OC)c1)Oc3cccc(Oc2nc(cc(OC)n2)OC)c3C([O-])=O","InChI=1/C18H16N4O8.Na/c1-26-12-7-11(23)19-17(20-12)29-9-5-4-6-10(15(9)16(24)25)30-18-21-13(27-2)8-14(22-18)28-3;/h4-8H,1-3H3,(H,24,25)(H,19,20,23);/q;+1/p-1","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","no data","with","Negative","","","RMS: Italy","Bispyribac-Sodium","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)","40476","2010","doi:10.2903/j.efsa.2010.1692" "Bispyribac-sodium","","125401-92-5","single chemical entity","Component is a metabolite of the substance","benzoic acid, 2-[(4,6-dimethoxy-2-pyrimidinyl)oxy]-6-[(4-hydroxy-6-methoxy-2-pyrimidinyl)oxy],sodium salt","","","sodium 2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-[(4-hydroxy-6-methoxypyrimidin-2-yl)oxy]benzoate","Not in list","C18H15N4NaO8","[Na+].Oc1nc(nc(OC)c1)Oc3cccc(Oc2nc(cc(OC)n2)OC)c3C([O-])=O","InChI=1/C18H16N4O8.Na/c1-26-12-7-11(23)19-17(20-12)29-9-5-4-6-10(15(9)16(24)25)30-18-21-13(27-2)8-14(22-18)28-3;/h4-8H,1-3H3,(H,24,25)(H,19,20,23);/q;+1/p-1","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","no data","with","Negative","","","RMS: Italy","Bispyribac-Sodium","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)","40476","2010","doi:10.2903/j.efsa.2010.1692" "Bispyribac-sodium","","125401-92-5","single chemical entity","Component is a metabolite of the substance","benzoic acid, 2-[(4,6-dimethoxy-2-pyrimidinyl)oxy]-6-[(4-hydroxy-6-methoxy-2-pyrimidinyl)oxy],sodium salt","","","sodium 2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-[(4-hydroxy-6-methoxypyrimidin-2-yl)oxy]benzoate","Not in list","C18H15N4NaO8","[Na+].Oc1nc(nc(OC)c1)Oc3cccc(Oc2nc(cc(OC)n2)OC)c3C([O-])=O","InChI=1/C18H16N4O8.Na/c1-26-12-7-11(23)19-17(20-12)29-9-5-4-6-10(15(9)16(24)25)30-18-21-13(27-2)8-14(22-18)28-3;/h4-8H,1-3H3,(H,24,25)(H,19,20,23);/q;+1/p-1","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","no data","with","Negative","","","RMS: Italy","Bispyribac-Sodium","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)","40476","2010","doi:10.2903/j.efsa.2010.1692" -"Benthiavalicarb-isopropyl","","177406-68-7","single chemical entity","Component is a metabolite of the substance","6,6'-difluoro-2,2'-dibenzothiazole","","","6,6?-difluoro-2,2?-bibenzo[d]thiazole","Not in list","C14H6F2N2S2","Fc1ccc2nc(sc2c1)c3nc4ccc(F)cc4s3","InChI=1S/C14H6F2N2S2/c15-7-1-3-9-11(5-7)19-13(17-9)14-18-10-4-2-8(16)6-12(10)20-14/h1-6H","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes","with","Positive","","","RMS: Belgium","Benthiavalicarb-isopropyl","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb","39295","2007","doi:10.2903/j.efsa.2007.107r" +"Benthiavalicarb-isopropyl","","177406-68-7","single chemical entity","Component is a metabolite of the substance","6,6'-difluoro-2,2'-dibenzothiazole","","","6,6'-difluoro-2,2'-bibenzo[d]thiazole","Not in list","C14H6F2N2S2","Fc1ccc2nc(sc2c1)c3nc4ccc(F)cc4s3","InChI=1S/C14H6F2N2S2/c15-7-1-3-9-11(5-7)19-13(17-9)14-18-10-4-2-8(16)6-12(10)20-14/h1-6H","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes","with","Positive","","","RMS: Belgium","Benthiavalicarb-isopropyl","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb","39295","2007","doi:10.2903/j.efsa.2007.107r" "Clethodim","","99129-21-2","single chemical entity","Component is identical to the substance","Clethodim","","99129-21-2","2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethylsulfanyl)propyl]-3-hydroxycyclohex-2-en-1-one","Clethodim","C17H26ClNO3S","CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)SCC)CC1=O","InChI=1S/C17H26ClNO3S/c1-4-14(19-22-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)23-5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Clethodim","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim","40837","2011","doi:10.2903/j.efsa.2011.2417" "Clethodim","","99129-21-2","single chemical entity","Component is identical to the substance","Clethodim","","99129-21-2","2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethylsulfanyl)propyl]-3-hydroxycyclohex-2-en-1-one","Clethodim","C17H26ClNO3S","CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)SCC)CC1=O","InChI=1S/C17H26ClNO3S/c1-4-14(19-22-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)23-5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Clethodim","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim","40837","2011","doi:10.2903/j.efsa.2011.2417" "Clethodim","","99129-21-2","single chemical entity","Component is identical to the substance","Clethodim","","99129-21-2","2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethylsulfanyl)propyl]-3-hydroxycyclohex-2-en-1-one","Clethodim","C17H26ClNO3S","CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)SCC)CC1=O","InChI=1S/C17H26ClNO3S/c1-4-14(19-22-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)23-5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Clethodim","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim","40837","2011","doi:10.2903/j.efsa.2011.2417" @@ -4210,48 +4210,48 @@ hydroxychromen-2-one","Bromadiolone","C30H23BrO4","C1=CC=C(C=C1)C(CC(C2=CC=C(C=C "Benalaxyl-M","","98243-83-5","single chemical entity","Component is identical to the substance","Benalaxyl-M","","98243-83-5","methyl N-(2,6-dimethylphenyl)-N-(phenylacetyl)-D-alaninate","Benalaxyl-M","C20H23NO3","C[C@@H](N(C(=O)Cc1ccccc1)c2c(C)cccc2C)C(=O)OC","InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3/t16-/m1/s1","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","CD-1","10","Male/Female","intraperitoneal","48","h","yes, concurrent vehicle","not applicable","Negative","","no evidence","RMS: Portugal","Benalaxyl-M","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.","41368","2013","doi:10.2903/j.efsa.2013.3148" "Benalaxyl-M","","98243-83-5","single chemical entity","Component is part of a group assessment","Benalaxyl","275-728-7","71626-11-4","Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate","Benalaxyl","C20H23NO3","CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2","InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","Rat (as animal)","Not reported","10","Male/Female","intraperitoneal","24","h","yes, concurrent vehicle","not applicable","Negative","","no evidence","RMS: Portugal","Benalaxyl-M","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.","41368","2013","doi:10.2903/j.efsa.2013.3148" "Benalaxyl-M","","98243-83-5","single chemical entity","Component is part of a group assessment","Benalaxyl","275-728-7","71626-11-4","Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate","Benalaxyl","C20H23NO3","CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2","InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","Rat (as animal)","Not reported","10","Male/Female","intraperitoneal","48","h","yes, concurrent vehicle","not applicable","Negative","","no evidence","RMS: Portugal","Benalaxyl-M","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.","41368","2013","doi:10.2903/j.efsa.2013.3148" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","CD-1","20","Male/Female","oral: gavage","48","h","yes, concurrent vehicle","not applicable","Negative","","no evidence","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","CD-1","20","Male/Female","oral: gavage","24","h","yes, concurrent vehicle","not applicable","Negative","","no evidence","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","CD-1","20","Male/Female","oral: gavage","48","h","yes, concurrent vehicle","not applicable","Negative","","no evidence","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","CD-1","20","Male/Female","oral: gavage","24","h","yes, concurrent vehicle","not applicable","Negative","","no evidence","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" "Cyantraniliprole","","736994-63-1","single chemical entity","Component is a metabolite of the substance","4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid","","","4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid","Not in list","C19H15BrClN5O4","O=C(O)c3cc(C)c(NC(=O)c2cc(Br)nn2c1ncccc1Cl)c(c3)C(=O)NC","InChI=1/C19H15BrClN5O4/c1-9-6-10(19(29)30)7-11(17(27)22-2)15(9)24-18(28)13-8-14(20)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)(H,29,30)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" "Cyantraniliprole","","736994-63-1","single chemical entity","Component is a metabolite of the substance","4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid","","","4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid","Not in list","C19H15BrClN5O4","O=C(O)c3cc(C)c(NC(=O)c2cc(Br)nn2c1ncccc1Cl)c(c3)C(=O)NC","InChI=1/C19H15BrClN5O4/c1-9-6-10(19(29)30)7-11(17(27)22-2)15(9)24-18(28)13-8-14(20)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)(H,29,30)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" "Cyantraniliprole","","736994-63-1","single chemical entity","Component is a metabolite of the substance","4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid","","","4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid","Not in list","C19H15BrClN5O4","O=C(O)c3cc(C)c(NC(=O)c2cc(Br)nn2c1ncccc1Cl)c(c3)C(=O)NC","InChI=1/C19H15BrClN5O4/c1-9-6-10(19(29)30)7-11(17(27)22-2)15(9)24-18(28)13-8-14(20)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)(H,29,30)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" @@ -4408,34 +4408,34 @@ hydroxychromen-2-one","Bromadiolone","C30H23BrO4","C1=CC=C(C=C1)C(CC(C2=CC=C(C=C "Eugenol","202-589-1","97-53-0","single chemical entity","Component is identical to the substance","Eugenol","202-589-1","97-53-0","2-Methoxy-4-prop-2-enylphenol","Not in list","C10H12O2","COC1=C(C=CC(=C1)CC=C)O","InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","Equivalent or similar to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No data","Acceptable","Human (as organism)","","","No data","oral: capsule","8","D","no data","not applicable","Negative","","","RMS: The United Kingdom","Eugenol (Final Addendum)","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol","41218","2012","doi:10.2903/j.efsa.2012.2914" "Eugenol","202-589-1","97-53-0","single chemical entity","Component is identical to the substance","Eugenol","202-589-1","97-53-0","2-Methoxy-4-prop-2-enylphenol","Not in list","C10H12O2","COC1=C(C=CC(=C1)CC=C)O","InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","chromosome aberration assay","in vivo","Equivalent or similar to","OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)","No data","Acceptable","Human (as organism)","","","No data","oral: capsule","8","D","no data","not applicable","Negative","","","RMS: The United Kingdom","Eugenol (Final Addendum)","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol","41218","2012","doi:10.2903/j.efsa.2012.2914" "Eugenol","202-589-1","97-53-0","single chemical entity","Component is identical to the substance","Eugenol","202-589-1","97-53-0","2-Methoxy-4-prop-2-enylphenol","Not in list","C10H12O2","COC1=C(C=CC(=C1)CC=C)O","InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","other","in vivo","No guideline available","Not reported","Not applicable","Acceptable","House mouse (as animal)","Not reported","","No data","intraperitoneal","","","no data","not applicable","Negative","","","RMS: The United Kingdom","Eugenol (Final Addendum)","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol","41218","2012","doi:10.2903/j.efsa.2012.2914" -"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4?-chloro-1-(3 chloro-2-pyridyl)-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" -"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4?-chloro-1-(3 chloro-2-pyridyl)-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" -"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4?-chloro-1-(3 chloro-2-pyridyl)-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" -"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4?-chloro-1-(3 chloro-2-pyridyl)-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" -"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4?-chloro-1-(3 chloro-2-pyridyl)-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" -"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4?-chloro-1-(3 chloro-2-pyridyl)-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" -"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4?-chloro-1-(3 chloro-2-pyridyl)-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" -"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4?-chloro-1-(3 chloro-2-pyridyl)-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" -"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4?-chloro-1-(3 chloro-2-pyridyl)-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" -"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4?-chloro-1-(3 chloro-2-pyridyl)-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" -"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4?-chloro-1-(3 chloro-2-pyridyl)-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" -"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4?-chloro-1-(3 chloro-2-pyridyl)-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" -"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4?-chloro-1-(3 chloro-2-pyridyl)-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" -"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4?-chloro-1-(3 chloro-2-pyridyl)-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" -"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4?-chloro-1-(3 chloro-2-pyridyl)-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" -"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4?-chloro-1-(3 chloro-2-pyridyl)-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" -"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4?-chloro-1-(3 chloro-2-pyridyl)-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" -"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4?-chloro-1-(3 chloro-2-pyridyl)-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" -"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4?-chloro-1-(3 chloro-2-pyridyl)-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" -"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4?-chloro-1-(3 chloro-2-pyridyl)-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" -"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4?-chloro-1-(3 chloro-2-pyridyl)-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" -"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4?-chloro-1-(3 chloro-2-pyridyl)-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" -"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4?-chloro-1-(3 chloro-2-pyridyl)-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" -"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4?-chloro-1-(3 chloro-2-pyridyl)-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" -"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4?-chloro-1-(3 chloro-2-pyridyl)-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" -"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4?-chloro-1-(3 chloro-2-pyridyl)-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" -"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4?-chloro-1-(3 chloro-2-pyridyl)-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","CD-1","10","Male/Female","oral: gavage","24","h","yes, concurrent vehicle","not applicable","Negative","","no evidence","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" -"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4?-chloro-1-(3 chloro-2-pyridyl)-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","CD-1","10","Male/Female","oral: gavage","48","h","yes, concurrent vehicle","not applicable","Negative","","no evidence","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" +"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" +"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" +"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" +"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" +"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" +"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" +"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" +"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" +"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" +"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" +"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" +"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" +"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" +"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" +"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" +"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" +"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" +"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" +"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" +"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" +"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" +"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" +"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" +"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" +"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" +"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" +"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","CD-1","10","Male/Female","oral: gavage","24","h","yes, concurrent vehicle","not applicable","Negative","","no evidence","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" +"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","CD-1","10","Male/Female","oral: gavage","48","h","yes, concurrent vehicle","not applicable","Negative","","no evidence","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" "Chlorantraniliprole","","500008-45-7","single chemical entity","Component is a metabolite of the substance","2-[3-bromo-1-(3-chloropyridin-2-yl)-1Hpyrazol-5-yl]-6-chloro-3,8-dimethylquinazolin-4(3H)-one","","","2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-6-chloro-3,8-dimethylquinazolin-4(3H)-one","Not in list","C18H12BrCl2N5O","Cc4cc(Cl)cc3c4N=C(c2cc(Br)nn2c1ncccc1Cl)N(C)C3=O","InChI=1/C18H12BrCl2N5O/c1-9-6-10(20)7-11-15(9)23-17(25(2)18(11)27)13-8-14(19)24-26(13)16-12(21)4-3-5-22-16/h3-8H,1-2H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" "Chlorantraniliprole","","500008-45-7","single chemical entity","Component is a metabolite of the substance","2-[3-bromo-1-(3-chloropyridin-2-yl)-1Hpyrazol-5-yl]-6-chloro-3,8-dimethylquinazolin-4(3H)-one","","","2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-6-chloro-3,8-dimethylquinazolin-4(3H)-one","Not in list","C18H12BrCl2N5O","Cc4cc(Cl)cc3c4N=C(c2cc(Br)nn2c1ncccc1Cl)N(C)C3=O","InChI=1/C18H12BrCl2N5O/c1-9-6-10(20)7-11-15(9)23-17(25(2)18(11)27)13-8-14(19)24-26(13)16-12(21)4-3-5-22-16/h3-8H,1-2H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" "Chlorantraniliprole","","500008-45-7","single chemical entity","Component is a metabolite of the substance","2-[3-bromo-1-(3-chloropyridin-2-yl)-1Hpyrazol-5-yl]-6-chloro-3,8-dimethylquinazolin-4(3H)-one","","","2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-6-chloro-3,8-dimethylquinazolin-4(3H)-one","Not in list","C18H12BrCl2N5O","Cc4cc(Cl)cc3c4N=C(c2cc(Br)nn2c1ncccc1Cl)N(C)C3=O","InChI=1/C18H12BrCl2N5O/c1-9-6-10(20)7-11-15(9)23-17(25(2)18(11)27)13-8-14(19)24-26(13)16-12(21)4-3-5-22-16/h3-8H,1-2H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" @@ -5008,35 +5008,35 @@ hydroxychromen-2-one","Bromadiolone","C30H23BrO4","C1=CC=C(C=C1)C(CC(C2=CC=C(C=C "Chloridazon","216-920-2","1698-60-8","single chemical entity","Component is a metabolite of the substance","5-amino-4-chloro-2-methyl-3(2H)-pyridazinone","605-639-4","17254-80-7","5-amino-4-chloro-2-methylpyridazin-3-one","Not in list","C5H6ClN3O","CN1C(=O)C(=C(C=N1)N)Cl","InChI=1S/C5H6ClN3O/c1-9-5(10)4(6)3(7)2-8-9/h2H,7H2,1H3","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro","in vitro","According to","OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)","No","Acceptable","Rat (as animal)","hepatocytes","","","Not reported","","","yes","without","Negative","","","RMS: Germany","Chloridazon","2004","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon","39307","2007","doi:10.2903/j.efsa.2007.108r" "Chloridazon","216-920-2","1698-60-8","single chemical entity","Component is a metabolite of the substance","5-amino-4-chloro-2-methyl-3(2H)-pyridazinone","605-639-4","17254-80-7","5-amino-4-chloro-2-methylpyridazin-3-one","Not in list","C5H6ClN3O","CN1C(=O)C(=C(C=N1)N)Cl","InChI=1S/C5H6ClN3O/c1-9-5(10)4(6)3(7)2-8-9/h2H,7H2,1H3","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","Rat (as animal)","Wistar","","Male","oral: unspecified","20","h","yes, concurrent vehicle","not applicable","Negative","","no evidence","RMS: Germany","Chloridazon","2004","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon","39307","2007","doi:10.2903/j.efsa.2007.108r" "Chloridazon","216-920-2","1698-60-8","single chemical entity","Component is a metabolite of the substance","5-amino-4-chloro-2-methyl-3(2H)-pyridazinone","605-639-4","17254-80-7","5-amino-4-chloro-2-methylpyridazin-3-one","Not in list","C5H6ClN3O","CN1C(=O)C(=C(C=N1)N)Cl","InChI=1S/C5H6ClN3O/c1-9-5(10)4(6)3(7)2-8-9/h2H,7H2,1H3","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","Rat (as animal)","Wistar","","Male","oral: unspecified","44","h","yes, concurrent vehicle","not applicable","Negative","","no evidence","RMS: Germany","Chloridazon","2004","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon","39307","2007","doi:10.2903/j.efsa.2007.108r" -"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 102","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 102","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Hamster (as animal)","lung fibroblasts (V79)","","","Not reported","","","yes","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Hamster (as animal)","lung fibroblasts (V79)","","","Not reported","","","yes","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","House mouse (as animal)","lymphoma L5178Y cells","","","Not reported","","","yes","without","Negative","no information","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","House mouse (as animal)","lymphoma L5178Y cells","","","Not reported","","","yes","with","Negative","no information","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","Bacillus subtilis recombination assay","in vitro","No guideline available","Not reported","Not applicable","Acceptable","Bacillus subtilis (as organism)","H17","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","Bacillus subtilis recombination assay","in vitro","No guideline available","Not reported","Not applicable","Acceptable","Bacillus subtilis (as organism)","M45","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","Bacillus subtilis recombination assay","in vitro","No guideline available","Not reported","Not applicable","Acceptable","Bacillus subtilis (as organism)","H17","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","Bacillus subtilis recombination assay","in vitro","No guideline available","Not reported","Not applicable","Acceptable","Bacillus subtilis (as organism)","M45","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","Rat (as animal)","Sprague-Dawley","10","Male/Female","intraperitoneal","24","h","yes, concurrent vehicle","not applicable","Negative","","no evidence","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 102","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 102","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Hamster (as animal)","lung fibroblasts (V79)","","","Not reported","","","yes","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Hamster (as animal)","lung fibroblasts (V79)","","","Not reported","","","yes","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","House mouse (as animal)","lymphoma L5178Y cells","","","Not reported","","","yes","without","Negative","no information","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","House mouse (as animal)","lymphoma L5178Y cells","","","Not reported","","","yes","with","Negative","no information","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","Bacillus subtilis recombination assay","in vitro","No guideline available","Not reported","Not applicable","Acceptable","Bacillus subtilis (as organism)","H17","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","Bacillus subtilis recombination assay","in vitro","No guideline available","Not reported","Not applicable","Acceptable","Bacillus subtilis (as organism)","M45","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","Bacillus subtilis recombination assay","in vitro","No guideline available","Not reported","Not applicable","Acceptable","Bacillus subtilis (as organism)","H17","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","Bacillus subtilis recombination assay","in vitro","No guideline available","Not reported","Not applicable","Acceptable","Bacillus subtilis (as organism)","M45","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","Rat (as animal)","Sprague-Dawley","10","Male/Female","intraperitoneal","24","h","yes, concurrent vehicle","not applicable","Negative","","no evidence","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" "Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N?-tert-butyl-N?-(5-methyl-6-chromancarbonyl)-5-methyl-6-chroman-carbohydrazide","","","","Not in list","","","","organic","no structure","","","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" "Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N?-tert-butyl-N?-(5-methyl-6-chromancarbonyl)-5-methyl-6-chroman-carbohydrazide","","","","Not in list","","","","organic","no structure","","","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" "Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N?-tert-butyl-N?-(5-methyl-6-chromancarbonyl)-5-methyl-6-chroman-carbohydrazide","","","","Not in list","","","","organic","no structure","","","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" @@ -5047,30 +5047,30 @@ hydroxychromen-2-one","Bromadiolone","C30H23BrO4","C1=CC=C(C=C1)C(CC(C2=CC=C(C=C "Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N?-tert-butyl-N?-(5-methyl-6-chromancarbonyl)-5-methyl-6-chroman-carbohydrazide","","","","Not in list","","","","organic","no structure","","","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" "Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N?-tert-butyl-N?-(5-methyl-6-chromancarbonyl)-5-methyl-6-chroman-carbohydrazide","","","","Not in list","","","","organic","no structure","","","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" "Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N?-tert-butyl-N?-(5-methyl-6-chromancarbonyl)-5-methyl-6-chroman-carbohydrazide","","","","Not in list","","","","organic","no structure","","","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","","","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","Not in list","C24H30N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C","InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","","","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","Not in list","C24H30N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C","InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","","","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","Not in list","C24H30N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C","InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","","","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","Not in list","C24H30N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C","InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","","","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","Not in list","C24H30N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C","InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","","","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","Not in list","C24H30N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C","InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","","","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","Not in list","C24H30N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C","InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","","","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","Not in list","C24H30N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C","InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","","","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","Not in list","C24H30N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C","InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","","","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","Not in list","C24H30N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C","InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","","","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","Not in list","C24H30N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C","InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","","","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","Not in list","C24H30N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C","InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","","","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","Not in list","C24H30N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C","InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","House mouse (as animal)","lymphoma L5178Y cells","","","Not reported","","","yes, concurrent vehicle","without","Negative","no information","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","","","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","Not in list","C24H30N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C","InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","House mouse (as animal)","lymphoma L5178Y cells","","","Not reported","","","yes, concurrent vehicle","with","Negative","no information","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N?-tert-butyl-N?-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","","","N?-tert-butyl-N?-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","Not in list","C24H28N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OC(=O)CCc2c3C)C(C)(C)C","InChI=1/C24H28N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)19-7-9-20-18(16(19)3)8-10-21(27)30-20/h7,9,11-13H,8,10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N?-tert-butyl-N?-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","","","N?-tert-butyl-N?-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","Not in list","C24H28N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OC(=O)CCc2c3C)C(C)(C)C","InChI=1/C24H28N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)19-7-9-20-18(16(19)3)8-10-21(27)30-20/h7,9,11-13H,8,10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N?-tert-butyl-N?-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","","","N?-tert-butyl-N?-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","Not in list","C24H28N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OC(=O)CCc2c3C)C(C)(C)C","InChI=1/C24H28N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)19-7-9-20-18(16(19)3)8-10-21(27)30-20/h7,9,11-13H,8,10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N?-tert-butyl-N?-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","","","N?-tert-butyl-N?-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","Not in list","C24H28N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OC(=O)CCc2c3C)C(C)(C)C","InChI=1/C24H28N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)19-7-9-20-18(16(19)3)8-10-21(27)30-20/h7,9,11-13H,8,10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N?-tert-butyl-N?-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","","","N?-tert-butyl-N?-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","Not in list","C24H28N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OC(=O)CCc2c3C)C(C)(C)C","InChI=1/C24H28N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)19-7-9-20-18(16(19)3)8-10-21(27)30-20/h7,9,11-13H,8,10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N?-tert-butyl-N?-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","","","N?-tert-butyl-N?-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","Not in list","C24H28N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OC(=O)CCc2c3C)C(C)(C)C","InChI=1/C24H28N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)19-7-9-20-18(16(19)3)8-10-21(27)30-20/h7,9,11-13H,8,10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N?-tert-butyl-N?-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","","","N?-tert-butyl-N?-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","Not in list","C24H28N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OC(=O)CCc2c3C)C(C)(C)C","InChI=1/C24H28N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)19-7-9-20-18(16(19)3)8-10-21(27)30-20/h7,9,11-13H,8,10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N?-tert-butyl-N?-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","","","N?-tert-butyl-N?-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","Not in list","C24H28N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OC(=O)CCc2c3C)C(C)(C)C","InChI=1/C24H28N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)19-7-9-20-18(16(19)3)8-10-21(27)30-20/h7,9,11-13H,8,10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N?-tert-butyl-N?-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","","","N?-tert-butyl-N?-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","Not in list","C24H28N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OC(=O)CCc2c3C)C(C)(C)C","InChI=1/C24H28N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)19-7-9-20-18(16(19)3)8-10-21(27)30-20/h7,9,11-13H,8,10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N?-tert-butyl-N?-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","","","N?-tert-butyl-N?-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","Not in list","C24H28N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OC(=O)CCc2c3C)C(C)(C)C","InChI=1/C24H28N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)19-7-9-20-18(16(19)3)8-10-21(27)30-20/h7,9,11-13H,8,10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","","","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","Not in list","C24H30N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C","InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","","","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","Not in list","C24H30N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C","InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","","","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","Not in list","C24H30N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C","InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","","","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","Not in list","C24H30N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C","InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","","","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","Not in list","C24H30N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C","InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","","","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","Not in list","C24H30N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C","InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","","","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","Not in list","C24H30N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C","InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","","","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","Not in list","C24H30N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C","InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","","","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","Not in list","C24H30N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C","InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","","","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","Not in list","C24H30N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C","InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","","","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","Not in list","C24H30N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C","InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","","","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","Not in list","C24H30N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C","InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","","","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","Not in list","C24H30N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C","InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","House mouse (as animal)","lymphoma L5178Y cells","","","Not reported","","","yes, concurrent vehicle","without","Negative","no information","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","","","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","Not in list","C24H30N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C","InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","House mouse (as animal)","lymphoma L5178Y cells","","","Not reported","","","yes, concurrent vehicle","with","Negative","no information","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","","","N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","Not in list","C24H28N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OC(=O)CCc2c3C)C(C)(C)C","InChI=1/C24H28N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)19-7-9-20-18(16(19)3)8-10-21(27)30-20/h7,9,11-13H,8,10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","","","N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","Not in list","C24H28N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OC(=O)CCc2c3C)C(C)(C)C","InChI=1/C24H28N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)19-7-9-20-18(16(19)3)8-10-21(27)30-20/h7,9,11-13H,8,10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","","","N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","Not in list","C24H28N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OC(=O)CCc2c3C)C(C)(C)C","InChI=1/C24H28N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)19-7-9-20-18(16(19)3)8-10-21(27)30-20/h7,9,11-13H,8,10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","","","N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","Not in list","C24H28N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OC(=O)CCc2c3C)C(C)(C)C","InChI=1/C24H28N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)19-7-9-20-18(16(19)3)8-10-21(27)30-20/h7,9,11-13H,8,10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","","","N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","Not in list","C24H28N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OC(=O)CCc2c3C)C(C)(C)C","InChI=1/C24H28N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)19-7-9-20-18(16(19)3)8-10-21(27)30-20/h7,9,11-13H,8,10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","","","N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","Not in list","C24H28N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OC(=O)CCc2c3C)C(C)(C)C","InChI=1/C24H28N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)19-7-9-20-18(16(19)3)8-10-21(27)30-20/h7,9,11-13H,8,10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","","","N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","Not in list","C24H28N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OC(=O)CCc2c3C)C(C)(C)C","InChI=1/C24H28N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)19-7-9-20-18(16(19)3)8-10-21(27)30-20/h7,9,11-13H,8,10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","","","N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","Not in list","C24H28N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OC(=O)CCc2c3C)C(C)(C)C","InChI=1/C24H28N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)19-7-9-20-18(16(19)3)8-10-21(27)30-20/h7,9,11-13H,8,10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","","","N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","Not in list","C24H28N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OC(=O)CCc2c3C)C(C)(C)C","InChI=1/C24H28N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)19-7-9-20-18(16(19)3)8-10-21(27)30-20/h7,9,11-13H,8,10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","","","N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","Not in list","C24H28N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OC(=O)CCc2c3C)C(C)(C)C","InChI=1/C24H28N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)19-7-9-20-18(16(19)3)8-10-21(27)30-20/h7,9,11-13H,8,10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" "Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","3-({1-tert-butyl-2-[(4-hydroxy-5-methyl-3,4-dihydro-2H-chromen-6-yl)carbonyl]hydrazinyl}carbonyl)-5-methylbenzoic acid","","","3-({1-tert-butyl-2-[(4-hydroxy-5-methyl-3,4-dihydro-2H-chromen-6-yl)carbonyl]hydrazinyl}carbonyl)-5-methylbenzoic acid","Not in list","C24H28N2O6","O=C(O)c1cc(C)cc(c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C","InChI=1/C24H28N2O6/c1-13-10-15(12-16(11-13)23(30)31)22(29)26(24(3,4)5)25-21(28)17-6-7-19-20(14(17)2)18(27)8-9-32-19/h6-7,10-12,18,27H,8-9H2,1-5H3,(H,25,28)(H,30,31)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" "Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","3-({1-tert-butyl-2-[(4-hydroxy-5-methyl-3,4-dihydro-2H-chromen-6-yl)carbonyl]hydrazinyl}carbonyl)-5-methylbenzoic acid","","","3-({1-tert-butyl-2-[(4-hydroxy-5-methyl-3,4-dihydro-2H-chromen-6-yl)carbonyl]hydrazinyl}carbonyl)-5-methylbenzoic acid","Not in list","C24H28N2O6","O=C(O)c1cc(C)cc(c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C","InChI=1/C24H28N2O6/c1-13-10-15(12-16(11-13)23(30)31)22(29)26(24(3,4)5)25-21(28)17-6-7-19-20(14(17)2)18(27)8-9-32-19/h6-7,10-12,18,27H,8-9H2,1-5H3,(H,25,28)(H,30,31)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" "Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","3-({1-tert-butyl-2-[(4-hydroxy-5-methyl-3,4-dihydro-2H-chromen-6-yl)carbonyl]hydrazinyl}carbonyl)-5-methylbenzoic acid","","","3-({1-tert-butyl-2-[(4-hydroxy-5-methyl-3,4-dihydro-2H-chromen-6-yl)carbonyl]hydrazinyl}carbonyl)-5-methylbenzoic acid","Not in list","C24H28N2O6","O=C(O)c1cc(C)cc(c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C","InChI=1/C24H28N2O6/c1-13-10-15(12-16(11-13)23(30)31)22(29)26(24(3,4)5)25-21(28)17-6-7-19-20(14(17)2)18(27)8-9-32-19/h6-7,10-12,18,27H,8-9H2,1-5H3,(H,25,28)(H,30,31)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" @@ -7965,23 +7965,23 @@ fluorophenyl}propanoic acid","Not in list","C13H10Cl2F3N3O3","CC1=NN(C(=O)N1C(F) "Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid","","","3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid","Not in list","C5H4F2N2O2","FC(F)c1nncc1C(=O)O","InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","no data","without","Negative","","","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" "Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid","","","3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid","Not in list","C5H4F2N2O2","FC(F)c1nncc1C(=O)O","InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11)","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","NMRI","5","Male","oral: unspecified","48","h","yes, concurrent vehicle","not applicable","Negative","","indirect-toxicokinetic investigations","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" "Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid","","","3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid","Not in list","C5H4F2N2O2","FC(F)c1nncc1C(=O)O","InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11)","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","NMRI","5","Male","oral: unspecified","24","h","yes, concurrent vehicle","not applicable","Negative","","indirect-toxicokinetic investigations","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" -"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" -"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" -"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" -"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" -"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" -"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" -"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" -"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" -"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" -"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" -"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Hamster (as animal)","lung fibroblasts (V79)","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" -"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Hamster (as animal)","lung fibroblasts (V79)","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" -"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","no data","without","Negative","","","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" -"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","no data","with","Negative","","","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" -"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","NMRI","5","Male","oral: unspecified","24","h","yes, concurrent vehicle","not applicable","Negative","","indirect-toxicokinetic investigations","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" -"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","NMRI","5","Male","oral: unspecified","48","h","yes, concurrent vehicle","not applicable","Negative","","indirect-toxicokinetic investigations","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" -"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","DNA damage and/or repair","unscheduled DNA synthesis","in vivo","According to","OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)","No","Acceptable","Rat (as animal)","Wistar","3","Male","oral: unspecified","14","h","yes, concurrent vehicle","not applicable","Negative","","","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" +"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" +"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" +"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" +"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" +"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" +"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" +"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" +"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" +"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" +"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" +"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Hamster (as animal)","lung fibroblasts (V79)","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" +"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Hamster (as animal)","lung fibroblasts (V79)","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" +"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","no data","without","Negative","","","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" +"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","no data","with","Negative","","","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" +"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","NMRI","5","Male","oral: unspecified","24","h","yes, concurrent vehicle","not applicable","Negative","","indirect-toxicokinetic investigations","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" +"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","NMRI","5","Male","oral: unspecified","48","h","yes, concurrent vehicle","not applicable","Negative","","indirect-toxicokinetic investigations","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" +"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","DNA damage and/or repair","unscheduled DNA synthesis","in vivo","According to","OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)","No","Acceptable","Rat (as animal)","Wistar","3","Male","oral: unspecified","14","h","yes, concurrent vehicle","not applicable","Negative","","","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" "Thifensulfuron-methyl","616-673-4","79277-27-3","single chemical entity","Component is identical to the substance","Thifensulfuron-methyl","616-673-4","79277-27-3","methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate","Thifensulfuron-methyl","C12H13N5O6S2","CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC","InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 97","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Thifensulfuron-methyl","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl","42208","2015","doi:10.2903/j.efsa.2015.4201" "Thifensulfuron-methyl","616-673-4","79277-27-3","single chemical entity","Component is identical to the substance","Thifensulfuron-methyl","616-673-4","79277-27-3","methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate","Thifensulfuron-methyl","C12H13N5O6S2","CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC","InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Thifensulfuron-methyl","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl","42208","2015","doi:10.2903/j.efsa.2015.4201" "Thifensulfuron-methyl","616-673-4","79277-27-3","single chemical entity","Component is identical to the substance","Thifensulfuron-methyl","616-673-4","79277-27-3","methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate","Thifensulfuron-methyl","C12H13N5O6S2","CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC","InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Thifensulfuron-methyl","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl","42208","2015","doi:10.2903/j.efsa.2015.4201" @@ -8471,8 +8471,8 @@ fluorophenyl}propanoic acid","Not in list","C13H10Cl2F3N3O3","CC1=NN(C(=O)N1C(F) "Bromuconazole","","116255-48-2","single chemical entity","Component is a metabolite of the substance","1-{[(2RS)-2-(2,4-dichlorophenyl)-2,5-dihydrofuran-2-yl]methyl}-1H-1,2,4-triazole","","","1-{[2-(2,4-dichlorophenyl)-2,5-dihydrofuran-2-yl]methyl}-1H-1,2,4-triazole","Not in list","C13H11Cl2N3O","Clc1cc(Cl)c(cc1)C2(C=CCO2)Cn3cncn3","InChI=1/C13H11Cl2N3O/c14-10-2-3-11(12(15)6-10)13(4-1-5-19-13)7-18-9-16-8-17-18/h1-4,6,8-9H,5,7H2","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Belgium","Bromuconazole","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole","40417","2010","doi:10.2903/j.efsa.2010.1704" "Carbosulfan","259-565-9","55285-14-8","single chemical entity","Component is identical to the substance","Carbosulfan","259-565-9","55285-14-8","2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate","Carbosulfan","C20H32N2O3S","CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12","InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3","organic","compound","Other","Other","chromosome aberration","chromosome aberration assay","in vivo","According to","OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)","No","Acceptable","House mouse (as animal)","ICR","10","Male/Female","oral: gavage","42","h","yes, concurrent vehicle","not applicable","Negative","","","RMS: Belgium","Carbosulfan (Addendum)","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan","40122","2009","doi:10.2903/j.efsa.2009.1354" "Carbosulfan","259-565-9","55285-14-8","single chemical entity","Component is identical to the substance","Carbosulfan","259-565-9","55285-14-8","2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate","Carbosulfan","C20H32N2O3S","CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12","InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3","organic","compound","Other","Other","chromosome aberration","chromosome aberration assay","in vivo","According to","OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)","No","Acceptable","House mouse (as animal)","ICR","10","Male/Female","oral: gavage","18","h","yes, concurrent vehicle","not applicable","Negative","","","RMS: Belgium","Carbosulfan (Addendum)","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan","40122","2009","doi:10.2903/j.efsa.2009.1354" -"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1?,2?-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","Not reported","","","Not reported","","","no data","no data","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" -"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1?,2?-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","Not reported","","No data","oral: gavage","","","no data","not applicable","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" +"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","Not reported","","","Not reported","","","no data","no data","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" +"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","Not reported","","No data","oral: gavage","","","no data","not applicable","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" "Clofentezine","277-728-2","74115-24-5","single chemical entity","Component is identical to the substance","Clofentezine","277-728-2","74115-24-5","3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine","Clofentezine","C14H8Cl2N4","Clc3ccccc3c1nnc(nn1)c2ccccc2Cl","InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes","with","Negative","","","RMS: The United Kingdom","Clofentezine (Addendum1)","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine","40014","2009","doi:10.2903/j.efsa.2009.269r" "Clofentezine","277-728-2","74115-24-5","single chemical entity","Component is identical to the substance","Clofentezine","277-728-2","74115-24-5","3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine","Clofentezine","C14H8Cl2N4","Clc3ccccc3c1nnc(nn1)c2ccccc2Cl","InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes","without","Negative","","","RMS: The United Kingdom","Clofentezine (Addendum1)","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine","40014","2009","doi:10.2903/j.efsa.2009.269r" "Clofentezine","277-728-2","74115-24-5","single chemical entity","Component is identical to the substance","Clofentezine","277-728-2","74115-24-5","3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine","Clofentezine","C14H8Cl2N4","Clc3ccccc3c1nnc(nn1)c2ccccc2Cl","InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes","without","Negative","","","RMS: The United Kingdom","Clofentezine (Addendum1)","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine","40014","2009","doi:10.2903/j.efsa.2009.269r" @@ -8816,16 +8816,16 @@ fluorophenyl}propanoic acid","Not in list","C13H10Cl2F3N3O3","CC1=NN(C(=O)N1C(F) "Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinane-2,4-dione","","","5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinane-2,4-dione","Not in list","C12H14N2O2S","CC(C)N2C(=O)SCN(c1ccccc1)C2=O","InChI=1/C12H14N2O2S/c1-9(2)14-11(15)13(8-17-12(14)16)10-6-4-3-5-7-10/h3-7,9H,8H2,1-2H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" "Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinane-2,4-dione","","","5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinane-2,4-dione","Not in list","C12H14N2O2S","CC(C)N2C(=O)SCN(c1ccccc1)C2=O","InChI=1/C12H14N2O2S/c1-9(2)14-11(15)13(8-17-12(14)16)10-6-4-3-5-7-10/h3-7,9H,8H2,1-2H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" "Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinane-2,4-dione","","","5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinane-2,4-dione","Not in list","C12H14N2O2S","CC(C)N2C(=O)SCN(c1ccccc1)C2=O","InChI=1/C12H14N2O2S/c1-9(2)14-11(15)13(8-17-12(14)16)10-6-4-3-5-7-10/h3-7,9H,8H2,1-2H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" -"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidic diamide","","","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidic diamide","Not in list","C15H23N3O2","O=C(Nc1ccccc1)N(C(=O)NC(C)(C)C)C(C)C","InChI=1/C15H23N3O2/c1-11(2)18(14(20)17-15(3,4)5)13(19)16-12-9-7-6-8-10-12/h6-11H,1-5H3,(H,16,19)(H,17,20)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" -"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidic diamide","","","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidic diamide","Not in list","C15H23N3O2","O=C(Nc1ccccc1)N(C(=O)NC(C)(C)C)C(C)C","InChI=1/C15H23N3O2/c1-11(2)18(14(20)17-15(3,4)5)13(19)16-12-9-7-6-8-10-12/h6-11H,1-5H3,(H,16,19)(H,17,20)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" -"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidic diamide","","","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidic diamide","Not in list","C15H23N3O2","O=C(Nc1ccccc1)N(C(=O)NC(C)(C)C)C(C)C","InChI=1/C15H23N3O2/c1-11(2)18(14(20)17-15(3,4)5)13(19)16-12-9-7-6-8-10-12/h6-11H,1-5H3,(H,16,19)(H,17,20)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" -"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidic diamide","","","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidic diamide","Not in list","C15H23N3O2","O=C(Nc1ccccc1)N(C(=O)NC(C)(C)C)C(C)C","InChI=1/C15H23N3O2/c1-11(2)18(14(20)17-15(3,4)5)13(19)16-12-9-7-6-8-10-12/h6-11H,1-5H3,(H,16,19)(H,17,20)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" -"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidic diamide","","","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidic diamide","Not in list","C15H23N3O2","O=C(Nc1ccccc1)N(C(=O)NC(C)(C)C)C(C)C","InChI=1/C15H23N3O2/c1-11(2)18(14(20)17-15(3,4)5)13(19)16-12-9-7-6-8-10-12/h6-11H,1-5H3,(H,16,19)(H,17,20)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" -"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidic diamide","","","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidic diamide","Not in list","C15H23N3O2","O=C(Nc1ccccc1)N(C(=O)NC(C)(C)C)C(C)C","InChI=1/C15H23N3O2/c1-11(2)18(14(20)17-15(3,4)5)13(19)16-12-9-7-6-8-10-12/h6-11H,1-5H3,(H,16,19)(H,17,20)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" -"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidic diamide","","","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidic diamide","Not in list","C15H23N3O2","O=C(Nc1ccccc1)N(C(=O)NC(C)(C)C)C(C)C","InChI=1/C15H23N3O2/c1-11(2)18(14(20)17-15(3,4)5)13(19)16-12-9-7-6-8-10-12/h6-11H,1-5H3,(H,16,19)(H,17,20)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" -"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidic diamide","","","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidic diamide","Not in list","C15H23N3O2","O=C(Nc1ccccc1)N(C(=O)NC(C)(C)C)C(C)C","InChI=1/C15H23N3O2/c1-11(2)18(14(20)17-15(3,4)5)13(19)16-12-9-7-6-8-10-12/h6-11H,1-5H3,(H,16,19)(H,17,20)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" -"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidic diamide","","","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidic diamide","Not in list","C15H23N3O2","O=C(Nc1ccccc1)N(C(=O)NC(C)(C)C)C(C)C","InChI=1/C15H23N3O2/c1-11(2)18(14(20)17-15(3,4)5)13(19)16-12-9-7-6-8-10-12/h6-11H,1-5H3,(H,16,19)(H,17,20)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" -"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidic diamide","","","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidic diamide","Not in list","C15H23N3O2","O=C(Nc1ccccc1)N(C(=O)NC(C)(C)C)C(C)C","InChI=1/C15H23N3O2/c1-11(2)18(14(20)17-15(3,4)5)13(19)16-12-9-7-6-8-10-12/h6-11H,1-5H3,(H,16,19)(H,17,20)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" +"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide","","","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide","Not in list","C15H23N3O2","O=C(Nc1ccccc1)N(C(=O)NC(C)(C)C)C(C)C","InChI=1/C15H23N3O2/c1-11(2)18(14(20)17-15(3,4)5)13(19)16-12-9-7-6-8-10-12/h6-11H,1-5H3,(H,16,19)(H,17,20)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" +"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide","","","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide","Not in list","C15H23N3O2","O=C(Nc1ccccc1)N(C(=O)NC(C)(C)C)C(C)C","InChI=1/C15H23N3O2/c1-11(2)18(14(20)17-15(3,4)5)13(19)16-12-9-7-6-8-10-12/h6-11H,1-5H3,(H,16,19)(H,17,20)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" +"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide","","","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide","Not in list","C15H23N3O2","O=C(Nc1ccccc1)N(C(=O)NC(C)(C)C)C(C)C","InChI=1/C15H23N3O2/c1-11(2)18(14(20)17-15(3,4)5)13(19)16-12-9-7-6-8-10-12/h6-11H,1-5H3,(H,16,19)(H,17,20)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" +"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide","","","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide","Not in list","C15H23N3O2","O=C(Nc1ccccc1)N(C(=O)NC(C)(C)C)C(C)C","InChI=1/C15H23N3O2/c1-11(2)18(14(20)17-15(3,4)5)13(19)16-12-9-7-6-8-10-12/h6-11H,1-5H3,(H,16,19)(H,17,20)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" +"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide","","","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide","Not in list","C15H23N3O2","O=C(Nc1ccccc1)N(C(=O)NC(C)(C)C)C(C)C","InChI=1/C15H23N3O2/c1-11(2)18(14(20)17-15(3,4)5)13(19)16-12-9-7-6-8-10-12/h6-11H,1-5H3,(H,16,19)(H,17,20)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" +"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide","","","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide","Not in list","C15H23N3O2","O=C(Nc1ccccc1)N(C(=O)NC(C)(C)C)C(C)C","InChI=1/C15H23N3O2/c1-11(2)18(14(20)17-15(3,4)5)13(19)16-12-9-7-6-8-10-12/h6-11H,1-5H3,(H,16,19)(H,17,20)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" +"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide","","","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide","Not in list","C15H23N3O2","O=C(Nc1ccccc1)N(C(=O)NC(C)(C)C)C(C)C","InChI=1/C15H23N3O2/c1-11(2)18(14(20)17-15(3,4)5)13(19)16-12-9-7-6-8-10-12/h6-11H,1-5H3,(H,16,19)(H,17,20)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" +"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide","","","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide","Not in list","C15H23N3O2","O=C(Nc1ccccc1)N(C(=O)NC(C)(C)C)C(C)C","InChI=1/C15H23N3O2/c1-11(2)18(14(20)17-15(3,4)5)13(19)16-12-9-7-6-8-10-12/h6-11H,1-5H3,(H,16,19)(H,17,20)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" +"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide","","","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide","Not in list","C15H23N3O2","O=C(Nc1ccccc1)N(C(=O)NC(C)(C)C)C(C)C","InChI=1/C15H23N3O2/c1-11(2)18(14(20)17-15(3,4)5)13(19)16-12-9-7-6-8-10-12/h6-11H,1-5H3,(H,16,19)(H,17,20)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" +"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide","","","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide","Not in list","C15H23N3O2","O=C(Nc1ccccc1)N(C(=O)NC(C)(C)C)C(C)C","InChI=1/C15H23N3O2/c1-11(2)18(14(20)17-15(3,4)5)13(19)16-12-9-7-6-8-10-12/h6-11H,1-5H3,(H,16,19)(H,17,20)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" "Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","1-phenyl-3-propan-2-ylurea","","19895-44-4","1-phenyl-3-propan-2-ylurea","Not in list","C10H14N2O","CC(C)NC(=O)NC1=CC=CC=C1","InChI=1S/C10H14N2O/c1-8(2)11-10(13)12-9-6-4-3-5-7-9/h3-8H,1-2H3,(H2,11,12,13)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" "Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","1-phenyl-3-propan-2-ylurea","","19895-44-4","1-phenyl-3-propan-2-ylurea","Not in list","C10H14N2O","CC(C)NC(=O)NC1=CC=CC=C1","InChI=1S/C10H14N2O/c1-8(2)11-10(13)12-9-6-4-3-5-7-9/h3-8H,1-2H3,(H2,11,12,13)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" "Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","1-phenyl-3-propan-2-ylurea","","19895-44-4","1-phenyl-3-propan-2-ylurea","Not in list","C10H14N2O","CC(C)NC(=O)NC1=CC=CC=C1","InChI=1S/C10H14N2O/c1-8(2)11-10(13)12-9-6-4-3-5-7-9/h3-8H,1-2H3,(H2,11,12,13)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" @@ -8836,16 +8836,16 @@ fluorophenyl}propanoic acid","Not in list","C13H10Cl2F3N3O3","CC1=NN(C(=O)N1C(F) "Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","1-phenyl-3-propan-2-ylurea","","19895-44-4","1-phenyl-3-propan-2-ylurea","Not in list","C10H14N2O","CC(C)NC(=O)NC1=CC=CC=C1","InChI=1S/C10H14N2O/c1-8(2)11-10(13)12-9-6-4-3-5-7-9/h3-8H,1-2H3,(H2,11,12,13)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" "Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","1-phenyl-3-propan-2-ylurea","","19895-44-4","1-phenyl-3-propan-2-ylurea","Not in list","C10H14N2O","CC(C)NC(=O)NC1=CC=CC=C1","InChI=1S/C10H14N2O/c1-8(2)11-10(13)12-9-6-4-3-5-7-9/h3-8H,1-2H3,(H2,11,12,13)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" "Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","1-phenyl-3-propan-2-ylurea","","19895-44-4","1-phenyl-3-propan-2-ylurea","Not in list","C10H14N2O","CC(C)NC(=O)NC1=CC=CC=C1","InChI=1S/C10H14N2O/c1-8(2)11-10(13)12-9-6-4-3-5-7-9/h3-8H,1-2H3,(H2,11,12,13)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" -"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidothioic diamide","","","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidothioic diamide","Not in list","C15H23N3OS","O=C(Nc1ccccc1)N(C(=S)NC(C)(C)C)C(C)C","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidothioic diamide","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" -"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidothioic diamide","","","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidothioic diamide","Not in list","C15H23N3OS","O=C(Nc1ccccc1)N(C(=S)NC(C)(C)C)C(C)C","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidothioic diamide","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" -"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidothioic diamide","","","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidothioic diamide","Not in list","C15H23N3OS","O=C(Nc1ccccc1)N(C(=S)NC(C)(C)C)C(C)C","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidothioic diamide","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" -"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidothioic diamide","","","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidothioic diamide","Not in list","C15H23N3OS","O=C(Nc1ccccc1)N(C(=S)NC(C)(C)C)C(C)C","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidothioic diamide","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" -"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidothioic diamide","","","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidothioic diamide","Not in list","C15H23N3OS","O=C(Nc1ccccc1)N(C(=S)NC(C)(C)C)C(C)C","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidothioic diamide","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" -"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidothioic diamide","","","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidothioic diamide","Not in list","C15H23N3OS","O=C(Nc1ccccc1)N(C(=S)NC(C)(C)C)C(C)C","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidothioic diamide","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" -"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidothioic diamide","","","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidothioic diamide","Not in list","C15H23N3OS","O=C(Nc1ccccc1)N(C(=S)NC(C)(C)C)C(C)C","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidothioic diamide","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" -"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidothioic diamide","","","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidothioic diamide","Not in list","C15H23N3OS","O=C(Nc1ccccc1)N(C(=S)NC(C)(C)C)C(C)C","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidothioic diamide","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" -"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidothioic diamide","","","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidothioic diamide","Not in list","C15H23N3OS","O=C(Nc1ccccc1)N(C(=S)NC(C)(C)C)C(C)C","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidothioic diamide","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" -"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidothioic diamide","","","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidothioic diamide","Not in list","C15H23N3OS","O=C(Nc1ccccc1)N(C(=S)NC(C)(C)C)C(C)C","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidothioic diamide","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" +"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide","","","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide","Not in list","C15H23N3OS","O=C(Nc1ccccc1)N(C(=S)NC(C)(C)C)C(C)C","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" +"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide","","","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide","Not in list","C15H23N3OS","O=C(Nc1ccccc1)N(C(=S)NC(C)(C)C)C(C)C","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" +"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide","","","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide","Not in list","C15H23N3OS","O=C(Nc1ccccc1)N(C(=S)NC(C)(C)C)C(C)C","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" +"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide","","","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide","Not in list","C15H23N3OS","O=C(Nc1ccccc1)N(C(=S)NC(C)(C)C)C(C)C","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" +"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide","","","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide","Not in list","C15H23N3OS","O=C(Nc1ccccc1)N(C(=S)NC(C)(C)C)C(C)C","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" +"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide","","","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide","Not in list","C15H23N3OS","O=C(Nc1ccccc1)N(C(=S)NC(C)(C)C)C(C)C","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" +"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide","","","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide","Not in list","C15H23N3OS","O=C(Nc1ccccc1)N(C(=S)NC(C)(C)C)C(C)C","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" +"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide","","","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide","Not in list","C15H23N3OS","O=C(Nc1ccccc1)N(C(=S)NC(C)(C)C)C(C)C","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" +"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide","","","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide","Not in list","C15H23N3OS","O=C(Nc1ccccc1)N(C(=S)NC(C)(C)C)C(C)C","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" +"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide","","","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide","Not in list","C15H23N3OS","O=C(Nc1ccccc1)N(C(=S)NC(C)(C)C)C(C)C","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" "Carfentrazone-ethyl","603-291-8","128639-02-1","single chemical entity","Component is a metabolite of the substance","(2E)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}acrylic acid","","","(2E)-3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}prop-2-enoic acid","Not in list","C13H9ClF3N3O3","O=C(O)/C=C/c1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F","InChI=1/C13H9ClF3N3O3/c1-6-18-20(13(23)19(6)12(16)17)10-4-7(2-3-11(21)22)8(14)5-9(10)15/h2-5,12H,1H3,(H,21,22)/b3-2+","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","Rat (as animal)","Sprague-Dawley","5","Male","oral: gavage","24","h","yes, concurrent vehicle","not applicable","Negative","","indirect-toxicokinetic investigations","RMS: Belgium - CoRMS: France","Carfentrazone-ethyl","2016","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl","42612","2016","doi:10.2903/j.efsa.2016.4569" "Carfentrazone-ethyl","603-291-8","128639-02-1","single chemical entity","Component is a metabolite of the substance","(2RS)-2-Chloro-3-{2-chloro-5-[4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid","","","2-chloro-3-{2-chloro-5-[4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid","Not in list","C12H8Cl2F3N3O3","O=C(O)C(Cl)Cc1cc(c(F)cc1Cl)N2N=CN(C2=O)C(F)F","InChI=1/C12H8Cl2F3N3O3/c13-6-3-8(15)9(2-5(6)1-7(14)10(21)22)20-12(23)19(4-18-20)11(16)17/h2-4,7,11H,1H2,(H,21,22)","organic","compound","Other","Other","chromosome aberration","in vitro mammalian cell micronucleus test","in vitro","According to","OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Belgium - CoRMS: France","Carfentrazone-ethyl","2016","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl","42612","2016","doi:10.2903/j.efsa.2016.4569" "Carfentrazone-ethyl","603-291-8","128639-02-1","single chemical entity","Component is a metabolite of the substance","(2RS)-2-Chloro-3-{2-chloro-5-[4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid","","","2-chloro-3-{2-chloro-5-[4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid","Not in list","C12H8Cl2F3N3O3","O=C(O)C(Cl)Cc1cc(c(F)cc1Cl)N2N=CN(C2=O)C(F)F","InChI=1/C12H8Cl2F3N3O3/c13-6-3-8(15)9(2-5(6)1-7(14)10(21)22)20-12(23)19(4-18-20)11(16)17/h2-4,7,11H,1H2,(H,21,22)","organic","compound","Other","Other","chromosome aberration","in vitro mammalian cell micronucleus test","in vitro","According to","OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Belgium - CoRMS: France","Carfentrazone-ethyl","2016","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl","42612","2016","doi:10.2903/j.efsa.2016.4569" @@ -13597,26 +13597,26 @@ acid","Imazaquin","C17H17N3O3","CC(C)C1(C(=O)NC(=N1)C2=NC3=CC=CC=C3C=C2C(=O)O)C" "Metalaxyl-M","615-135-6","70630-17-0","single chemical entity","Component is a metabolite of the substance","N-(2,6-Dimethyl-phenyl)-2-methoxy-acetamide","","","N-(2,6-dimethylphenyl)-2-methoxyacetamide","Not in list","C11H15NO2","O=C(Nc1c(C)cccc1C)COC","InChI=1S/C11H15NO2/c1-8-5-4-6-9(2)11(8)12-10(13)7-14-3/h4-6H,7H2,1-3H3,(H,12,13)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","Equivalent or similar to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","Yes","Acceptable","House mouse (as animal)","lymphoma L5178Y cells","","","Not reported","","","yes","with","Negative","small colonies","","RMS: Belgium - CoRMS: Greece","Metalaxyl-M","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M","42066","2015","doi:10.2903/j.efsa.2015.3999" "Metalaxyl-M","615-135-6","70630-17-0","single chemical entity","Component is a metabolite of the substance","N-(2,6-Dimethyl-phenyl)-2-methoxy-acetamide","","","N-(2,6-dimethylphenyl)-2-methoxyacetamide","Not in list","C11H15NO2","O=C(Nc1c(C)cccc1C)COC","InChI=1S/C11H15NO2/c1-8-5-4-6-9(2)11(8)12-10(13)7-14-3/h4-6H,7H2,1-3H3,(H,12,13)","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Belgium - CoRMS: Greece","Metalaxyl-M","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M","42066","2015","doi:10.2903/j.efsa.2015.3999" "Metalaxyl-M","615-135-6","70630-17-0","single chemical entity","Component is a metabolite of the substance","N-(2,6-Dimethyl-phenyl)-2-methoxy-acetamide","","","N-(2,6-dimethylphenyl)-2-methoxyacetamide","Not in list","C11H15NO2","O=C(Nc1c(C)cccc1C)COC","InChI=1S/C11H15NO2/c1-8-5-4-6-9(2)11(8)12-10(13)7-14-3/h4-6H,7H2,1-3H3,(H,12,13)","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Belgium - CoRMS: Greece","Metalaxyl-M","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M","42066","2015","doi:10.2903/j.efsa.2015.3999" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 102","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 102","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","lung fibroblasts (V79)","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","lung fibroblasts (V79)","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","Tif:MAGf(SPF)","16","Male/Female","oral: gavage","24","h","yes, concurrent vehicle","not applicable","Negative","","indirect evidence-systemic toxicity","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","Tif:MAGf(SPF)","16","Male/Female","oral: gavage","48","h","yes, concurrent vehicle","not applicable","Negative","","indirect evidence-systemic toxicity","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","Tif:MAGf(SPF)","16","Male/Female","oral: gavage","24","h","yes, concurrent vehicle","not applicable","Negative","","indirect evidence-systemic toxicity","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","Tif:MAGf(SPF)","16","Male/Female","oral: gavage","16","h","yes, concurrent vehicle","not applicable","Negative","","indirect evidence-systemic toxicity","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 102","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 102","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","lung fibroblasts (V79)","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","lung fibroblasts (V79)","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","Tif:MAGf(SPF)","16","Male/Female","oral: gavage","24","h","yes, concurrent vehicle","not applicable","Negative","","indirect evidence-systemic toxicity","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","Tif:MAGf(SPF)","16","Male/Female","oral: gavage","48","h","yes, concurrent vehicle","not applicable","Negative","","indirect evidence-systemic toxicity","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","Tif:MAGf(SPF)","16","Male/Female","oral: gavage","24","h","yes, concurrent vehicle","not applicable","Negative","","indirect evidence-systemic toxicity","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","Tif:MAGf(SPF)","16","Male/Female","oral: gavage","16","h","yes, concurrent vehicle","not applicable","Negative","","indirect evidence-systemic toxicity","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" "Imazalil","252-615-0","35554-44-0","single chemical entity","Component is identical to the substance","Imazalil","252-615-0","35554-44-0","1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole","Imazalil","C14H14Cl2N2O","C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl","InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1538","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands - CoRMS: Spain","Imazalil","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil","40256","2010","doi:10.2903/j.efsa.2010.1526" "Imazalil","252-615-0","35554-44-0","single chemical entity","Component is identical to the substance","Imazalil","252-615-0","35554-44-0","1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole","Imazalil","C14H14Cl2N2O","C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl","InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1538","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands - CoRMS: Spain","Imazalil","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil","40256","2010","doi:10.2903/j.efsa.2010.1526" "Imazalil","252-615-0","35554-44-0","single chemical entity","Component is identical to the substance","Imazalil","252-615-0","35554-44-0","1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole","Imazalil","C14H14Cl2N2O","C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl","InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands - CoRMS: Spain","Imazalil","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil","40256","2010","doi:10.2903/j.efsa.2010.1526" @@ -13630,23 +13630,23 @@ acid","Imazaquin","C17H17N3O3","CC(C)C1(C(=O)NC(=N1)C2=NC3=CC=CC=C3C=C2C(=O)O)C" "Imazalil","252-615-0","35554-44-0","single chemical entity","Component is identical to the substance","Imazalil","252-615-0","35554-44-0","1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole","Imazalil","C14H14Cl2N2O","C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl","InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","Equivalent or similar to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No data","Acceptable","Rat (as animal)","Not reported","","No data","intraperitoneal","","","no data","not applicable","Negative","","","RMS: The Netherlands - CoRMS: Spain","Imazalil","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil","40256","2010","doi:10.2903/j.efsa.2010.1526" "Imazalil","252-615-0","35554-44-0","single chemical entity","Component is identical to the substance","Imazalil","252-615-0","35554-44-0","1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole","Imazalil","C14H14Cl2N2O","C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl","InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2","organic","compound","PubChem canonical SMILES","PubChem InChI","genome mutation","Drosophila SLRL test","in vivo","Equivalent or similar to","OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster)","No data","Acceptable","Drosophila melanogaster (as animal)","Not reported","","Male","Not reported","3","D","no data","not applicable","Negative","","","RMS: The Netherlands - CoRMS: Spain","Imazalil","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil","40256","2010","doi:10.2903/j.efsa.2010.1526" "Imazalil","252-615-0","35554-44-0","single chemical entity","Component is identical to the substance","Imazalil","252-615-0","35554-44-0","1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole","Imazalil","C14H14Cl2N2O","C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl","InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","single cell gel/comet assay in mammalian cells for detection of DNA damage","in vitro","No guideline available","Not reported","Not applicable","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes","no data","Positive","","","RMS: The Netherlands - CoRMS: Spain","Imazalil","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil","40256","2010","doi:10.2903/j.efsa.2010.1526" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1538","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1538","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","without","Positive","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","Equivalent or similar to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","Yes","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","Equivalent or similar to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","Yes","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes","without","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","Swiss","10","Male/Female","oral: gavage","72","h","yes, concurrent vehicle","not applicable","Negative","","direct evidence-cytotoxicity$indirect evidence-systemic toxicity","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","Swiss","10","Male/Female","oral: gavage","48","h","yes, concurrent vehicle","not applicable","Negative","","direct evidence-cytotoxicity$indirect evidence-systemic toxicity","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","Swiss","10","Male/Female","oral: gavage","24","h","yes, concurrent vehicle","not applicable","Negative","","direct evidence-cytotoxicity$indirect evidence-systemic toxicity","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1538","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1538","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","without","Positive","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","Equivalent or similar to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","Yes","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","Equivalent or similar to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","Yes","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes","without","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","Swiss","10","Male/Female","oral: gavage","72","h","yes, concurrent vehicle","not applicable","Negative","","direct evidence-cytotoxicity$indirect evidence-systemic toxicity","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","Swiss","10","Male/Female","oral: gavage","48","h","yes, concurrent vehicle","not applicable","Negative","","direct evidence-cytotoxicity$indirect evidence-systemic toxicity","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","Swiss","10","Male/Female","oral: gavage","24","h","yes, concurrent vehicle","not applicable","Negative","","direct evidence-cytotoxicity$indirect evidence-systemic toxicity","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" "Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is a metabolite of the substance","Desethyl-hydroxy-terbuthylazine","","","4-amino-6-(tert-butylamino)-1,3,5-triazin-2-ol","Desethyl-hydroxy-terbuthylazine","C7H13N5O","Nc1nc(NC(C)(C)C)nc(O)n1","InChI=1S/C7H13N5O/c1-7(2,3)12-5-9-4(8)10-6(13)11-5/h1-3H3,(H4,8,9,10,11,12,13)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" "Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is a metabolite of the substance","Desethyl-hydroxy-terbuthylazine","","","4-amino-6-(tert-butylamino)-1,3,5-triazin-2-ol","Desethyl-hydroxy-terbuthylazine","C7H13N5O","Nc1nc(NC(C)(C)C)nc(O)n1","InChI=1S/C7H13N5O/c1-7(2,3)12-5-9-4(8)10-6(13)11-5/h1-3H3,(H4,8,9,10,11,12,13)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 102","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" "Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is a metabolite of the substance","Desethyl-hydroxy-terbuthylazine","","","4-amino-6-(tert-butylamino)-1,3,5-triazin-2-ol","Desethyl-hydroxy-terbuthylazine","C7H13N5O","Nc1nc(NC(C)(C)C)nc(O)n1","InChI=1S/C7H13N5O/c1-7(2,3)12-5-9-4(8)10-6(13)11-5/h1-3H3,(H4,8,9,10,11,12,13)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" @@ -13709,16 +13709,16 @@ acid","Imazaquin","C17H17N3O3","CC(C)C1(C(=O)NC(=N1)C2=NC3=CC=CC=C3C=C2C(=O)O)C" "Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is a metabolite of the substance","Desethyl-terbuthylazine","","30125-63-4","2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine","Terbuthylazine, Desethyl-","C7H12ClN5","CC(C)(C)NC1=NC(=NC(=N1)N)Cl","InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" "Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is a metabolite of the substance","Desethyl-terbuthylazine","","30125-63-4","2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine","Terbuthylazine, Desethyl-","C7H12ClN5","CC(C)(C)NC1=NC(=NC(=N1)N)Cl","InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" "Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is a metabolite of the substance","Desethyl-terbuthylazine","","30125-63-4","2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine","Terbuthylazine, Desethyl-","C7H12ClN5","CC(C)(C)NC1=NC(=NC(=N1)N)Cl","InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine (Additional report)","2010","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine (Additional report)","2010","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine (Additional report)","2010","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine (Additional report)","2010","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine (Additional report)","2010","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine (Additional report)","2010","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine (Additional report)","2010","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine (Additional report)","2010","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine (Additional report)","2010","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine (Additional report)","2010","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine (Additional report)","2010","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine (Additional report)","2010","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine (Additional report)","2010","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine (Additional report)","2010","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine (Additional report)","2010","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine (Additional report)","2010","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine (Additional report)","2010","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine (Additional report)","2010","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine (Additional report)","2010","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine (Additional report)","2010","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" "Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is a metabolite of the substance","Desethyl-terbuthylazine","","30125-63-4","2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine","Terbuthylazine, Desethyl-","C7H12ClN5","CC(C)(C)NC1=NC(=NC(=N1)N)Cl","InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine (Additional report)","2010","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" "Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is a metabolite of the substance","Desethyl-terbuthylazine","","30125-63-4","2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine","Terbuthylazine, Desethyl-","C7H12ClN5","CC(C)(C)NC1=NC(=NC(=N1)N)Cl","InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine (Additional report)","2010","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" "Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is a metabolite of the substance","Desethyl-terbuthylazine","","30125-63-4","2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine","Terbuthylazine, Desethyl-","C7H12ClN5","CC(C)(C)NC1=NC(=NC(=N1)N)Cl","InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine (Additional report)","2010","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" @@ -15603,14 +15603,14 @@ butanoyl]amino]propanoate","Valifenalate","C19H27ClN2O5","CC(C)[C@@H](C(=O)NC(CC "Spirodiclofen","","148477-71-8","single chemical entity","Component is identical to the substance","Spirodiclofen","","148477-71-8","3-(3,5-dichlorophenyl)-2-oxo-1-oxaspiro[4.5]dec-3-en-4-yl 2,2-dimethylbutanoate","Spirodiclofen","C21H24Cl2O4","O=C2OC1(C(OC(C(CC)(C)C)=O)=C2C3=CC(Cl)=CC(Cl)=C3)CCCCC1","InChI=1S/C21H24Cl2O4/c1-4-20(2,3)19(25)26-17-16(13-10-14(22)12-15(23)11-13)18(24)27-21(17)8-6-5-7-9-21/h10-12H,4-9H2,1-3H3","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","Not reported","10","Male/Female","intraperitoneal","48","h","yes","not applicable","Negative","","direct evidence-cytotoxicity","RMS: The Netherlands","Spirodiclofen","2004","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance spirodiclofen","40031","2009","doi:10.2903/j.efsa.2009.339r" "Spirodiclofen","","148477-71-8","single chemical entity","Component is identical to the substance","Spirodiclofen","","148477-71-8","3-(3,5-dichlorophenyl)-2-oxo-1-oxaspiro[4.5]dec-3-en-4-yl 2,2-dimethylbutanoate","Spirodiclofen","C21H24Cl2O4","O=C2OC1(C(OC(C(CC)(C)C)=O)=C2C3=CC(Cl)=CC(Cl)=C3)CCCCC1","InChI=1S/C21H24Cl2O4/c1-4-20(2,3)19(25)26-17-16(13-10-14(22)12-15(23)11-13)18(24)27-21(17)8-6-5-7-9-21/h10-12H,4-9H2,1-3H3","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","Not reported","10","Male/Female","intraperitoneal","24","h","yes","not applicable","Negative","","direct evidence-cytotoxicity","RMS: The Netherlands","Spirodiclofen","2004","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance spirodiclofen","40031","2009","doi:10.2903/j.efsa.2009.339r" "Spirodiclofen","","148477-71-8","single chemical entity","Component is identical to the substance","Spirodiclofen","","148477-71-8","3-(3,5-dichlorophenyl)-2-oxo-1-oxaspiro[4.5]dec-3-en-4-yl 2,2-dimethylbutanoate","Spirodiclofen","C21H24Cl2O4","O=C2OC1(C(OC(C(CC)(C)C)=O)=C2C3=CC(Cl)=CC(Cl)=C3)CCCCC1","InChI=1S/C21H24Cl2O4/c1-4-20(2,3)19(25)26-17-16(13-10-14(22)12-15(23)11-13)18(24)27-21(17)8-6-5-7-9-21/h10-12H,4-9H2,1-3H3","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","Not reported","10","Male/Female","intraperitoneal","16","h","yes","not applicable","Negative","","direct evidence-cytotoxicity","RMS: The Netherlands","Spirodiclofen","2004","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance spirodiclofen","40031","2009","doi:10.2903/j.efsa.2009.339r" -"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST-glucoside","","","N,N-dimethyl-N?-[(4-(YA-D-glucopyranosyl)-methylphenyl]sulfamide","Not in list","C16H26N2O8S","CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2","InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" -"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST-glucoside","","","N,N-dimethyl-N?-[(4-(YA-D-glucopyranosyl)-methylphenyl]sulfamide","Not in list","C16H26N2O8S","CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2","InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" -"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST-glucoside","","","N,N-dimethyl-N?-[(4-(YA-D-glucopyranosyl)-methylphenyl]sulfamide","Not in list","C16H26N2O8S","CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2","InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" -"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST-glucoside","","","N,N-dimethyl-N?-[(4-(YA-D-glucopyranosyl)-methylphenyl]sulfamide","Not in list","C16H26N2O8S","CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2","InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" -"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST-glucoside","","","N,N-dimethyl-N?-[(4-(YA-D-glucopyranosyl)-methylphenyl]sulfamide","Not in list","C16H26N2O8S","CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2","InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" -"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST-glucoside","","","N,N-dimethyl-N?-[(4-(YA-D-glucopyranosyl)-methylphenyl]sulfamide","Not in list","C16H26N2O8S","CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2","InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" -"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST-glucoside","","","N,N-dimethyl-N?-[(4-(YA-D-glucopyranosyl)-methylphenyl]sulfamide","Not in list","C16H26N2O8S","CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2","InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" -"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST-glucoside","","","N,N-dimethyl-N?-[(4-(YA-D-glucopyranosyl)-methylphenyl]sulfamide","Not in list","C16H26N2O8S","CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2","InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" +"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST-glucoside","","","N,N-dimethyl-N?-[(4-(ñ-D-glucopyranosyl)-methylphenyl]sulfamide","Not in list","C16H26N2O8S","CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2","InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" +"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST-glucoside","","","N,N-dimethyl-N?-[(4-(ñ-D-glucopyranosyl)-methylphenyl]sulfamide","Not in list","C16H26N2O8S","CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2","InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" +"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST-glucoside","","","N,N-dimethyl-N?-[(4-(ñ-D-glucopyranosyl)-methylphenyl]sulfamide","Not in list","C16H26N2O8S","CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2","InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" +"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST-glucoside","","","N,N-dimethyl-N?-[(4-(ñ-D-glucopyranosyl)-methylphenyl]sulfamide","Not in list","C16H26N2O8S","CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2","InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" +"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST-glucoside","","","N,N-dimethyl-N?-[(4-(ñ-D-glucopyranosyl)-methylphenyl]sulfamide","Not in list","C16H26N2O8S","CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2","InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" +"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST-glucoside","","","N,N-dimethyl-N?-[(4-(ñ-D-glucopyranosyl)-methylphenyl]sulfamide","Not in list","C16H26N2O8S","CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2","InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" +"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST-glucoside","","","N,N-dimethyl-N?-[(4-(ñ-D-glucopyranosyl)-methylphenyl]sulfamide","Not in list","C16H26N2O8S","CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2","InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" +"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST-glucoside","","","N,N-dimethyl-N?-[(4-(ñ-D-glucopyranosyl)-methylphenyl]sulfamide","Not in list","C16H26N2O8S","CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2","InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" "Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is identical to the substance","Tolylfluanid","211-986-9","731-27-1","N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline","Tolylfluanid","C10H13Cl2FN2O2S2","CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C","InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" "Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is identical to the substance","Tolylfluanid","211-986-9","731-27-1","N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline","Tolylfluanid","C10H13Cl2FN2O2S2","CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C","InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" "Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is identical to the substance","Tolylfluanid","211-986-9","731-27-1","N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline","Tolylfluanid","C10H13Cl2FN2O2S2","CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C","InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" @@ -15648,30 +15648,30 @@ butanoyl]amino]propanoate","Valifenalate","C19H27ClN2O5","CC(C)[C@@H](C(=O)NC(CC "Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is identical to the substance","Tolylfluanid","211-986-9","731-27-1","N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline","Tolylfluanid","C10H13Cl2FN2O2S2","CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C","InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","other","in vivo","No guideline followed","Not reported","Not applicable","Acceptable","Rat (as animal)","Wistar","","No data","oral: feed","12","D","yes","not applicable","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" "Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is identical to the substance","Tolylfluanid","211-986-9","731-27-1","N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline","Tolylfluanid","C10H13Cl2FN2O2S2","CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C","InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","other","in vivo","No guideline followed","Not reported","Not applicable","Acceptable","Rat (as animal)","Wistar","","No data","oral: feed","12","D","yes","not applicable","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" "Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is identical to the substance","Tolylfluanid","211-986-9","731-27-1","N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline","Tolylfluanid","C10H13Cl2FN2O2S2","CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C","InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","other","in vivo","No guideline followed","Not reported","Not applicable","Acceptable","Rat (as animal)","Wistar","","No data","oral: feed","12","D","yes","not applicable","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" -"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST","","","N?-[4-(hydroxymethyl)phenyl]-N,N-dimethylsulfamide","Not in list","C9H14N2O3S","O=S(=O)(Nc1ccc(cc1)CO)N(C)C","InChI=1/C9H14N2O3S/c1-11(2)15(13,14)10-9-5-3-8(7-12)4-6-9/h3-6,10,12H,7H2,1-2H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" -"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST","","","N?-[4-(hydroxymethyl)phenyl]-N,N-dimethylsulfamide","Not in list","C9H14N2O3S","O=S(=O)(Nc1ccc(cc1)CO)N(C)C","InChI=1/C9H14N2O3S/c1-11(2)15(13,14)10-9-5-3-8(7-12)4-6-9/h3-6,10,12H,7H2,1-2H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" -"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST","","","N?-[4-(hydroxymethyl)phenyl]-N,N-dimethylsulfamide","Not in list","C9H14N2O3S","O=S(=O)(Nc1ccc(cc1)CO)N(C)C","InChI=1/C9H14N2O3S/c1-11(2)15(13,14)10-9-5-3-8(7-12)4-6-9/h3-6,10,12H,7H2,1-2H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" -"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST","","","N?-[4-(hydroxymethyl)phenyl]-N,N-dimethylsulfamide","Not in list","C9H14N2O3S","O=S(=O)(Nc1ccc(cc1)CO)N(C)C","InChI=1/C9H14N2O3S/c1-11(2)15(13,14)10-9-5-3-8(7-12)4-6-9/h3-6,10,12H,7H2,1-2H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" -"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST","","","N?-[4-(hydroxymethyl)phenyl]-N,N-dimethylsulfamide","Not in list","C9H14N2O3S","O=S(=O)(Nc1ccc(cc1)CO)N(C)C","InChI=1/C9H14N2O3S/c1-11(2)15(13,14)10-9-5-3-8(7-12)4-6-9/h3-6,10,12H,7H2,1-2H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" -"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST","","","N?-[4-(hydroxymethyl)phenyl]-N,N-dimethylsulfamide","Not in list","C9H14N2O3S","O=S(=O)(Nc1ccc(cc1)CO)N(C)C","InChI=1/C9H14N2O3S/c1-11(2)15(13,14)10-9-5-3-8(7-12)4-6-9/h3-6,10,12H,7H2,1-2H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" -"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST","","","N?-[4-(hydroxymethyl)phenyl]-N,N-dimethylsulfamide","Not in list","C9H14N2O3S","O=S(=O)(Nc1ccc(cc1)CO)N(C)C","InChI=1/C9H14N2O3S/c1-11(2)15(13,14)10-9-5-3-8(7-12)4-6-9/h3-6,10,12H,7H2,1-2H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" -"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST","","","N?-[4-(hydroxymethyl)phenyl]-N,N-dimethylsulfamide","Not in list","C9H14N2O3S","O=S(=O)(Nc1ccc(cc1)CO)N(C)C","InChI=1/C9H14N2O3S/c1-11(2)15(13,14)10-9-5-3-8(7-12)4-6-9/h3-6,10,12H,7H2,1-2H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" -"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST-glucoside","","","N,N-dimethyl-N?-[(4-(YA-D-glucopyranosyl)-methylphenyl]sulfamide","Not in list","C16H26N2O8S","CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2","InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" -"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST-glucoside","","","N,N-dimethyl-N?-[(4-(YA-D-glucopyranosyl)-methylphenyl]sulfamide","Not in list","C16H26N2O8S","CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2","InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" -"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST-glucoside","","","N,N-dimethyl-N?-[(4-(YA-D-glucopyranosyl)-methylphenyl]sulfamide","Not in list","C16H26N2O8S","CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2","InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" -"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST-glucoside","","","N,N-dimethyl-N?-[(4-(YA-D-glucopyranosyl)-methylphenyl]sulfamide","Not in list","C16H26N2O8S","CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2","InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" -"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST-glucoside","","","N,N-dimethyl-N?-[(4-(YA-D-glucopyranosyl)-methylphenyl]sulfamide","Not in list","C16H26N2O8S","CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2","InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" -"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST-glucoside","","","N,N-dimethyl-N?-[(4-(YA-D-glucopyranosyl)-methylphenyl]sulfamide","Not in list","C16H26N2O8S","CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2","InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" -"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST-glucoside","","","N,N-dimethyl-N?-[(4-(YA-D-glucopyranosyl)-methylphenyl]sulfamide","Not in list","C16H26N2O8S","CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2","InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" -"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST-glucoside","","","N,N-dimethyl-N?-[(4-(YA-D-glucopyranosyl)-methylphenyl]sulfamide","Not in list","C16H26N2O8S","CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2","InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" -"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","2-Hydroxyphenyl-DMST-glucoside","","","N,N-dimethyl-N?-[[2-(YA-D-glucopyranosyl)-4-methyl]phenyl]sulfamide","Not in list","C15H24N2O8S","CN(C)S(=O)(=O)Nc2ccc(C)cc2OC1OC(CO)C(O)C(O)C1O","InChI=1/C15H24N2O8S/c1-8-4-5-9(16-26(22,23)17(2)3)10(6-8)24-15-14(21)13(20)12(19)11(7-18)25-15/h4-6,11-16,18-21H,7H2,1-3H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" -"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","2-Hydroxyphenyl-DMST-glucoside","","","N,N-dimethyl-N?-[[2-(YA-D-glucopyranosyl)-4-methyl]phenyl]sulfamide","Not in list","C15H24N2O8S","CN(C)S(=O)(=O)Nc2ccc(C)cc2OC1OC(CO)C(O)C(O)C1O","InChI=1/C15H24N2O8S/c1-8-4-5-9(16-26(22,23)17(2)3)10(6-8)24-15-14(21)13(20)12(19)11(7-18)25-15/h4-6,11-16,18-21H,7H2,1-3H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" -"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","2-Hydroxyphenyl-DMST-glucoside","","","N,N-dimethyl-N?-[[2-(YA-D-glucopyranosyl)-4-methyl]phenyl]sulfamide","Not in list","C15H24N2O8S","CN(C)S(=O)(=O)Nc2ccc(C)cc2OC1OC(CO)C(O)C(O)C1O","InChI=1/C15H24N2O8S/c1-8-4-5-9(16-26(22,23)17(2)3)10(6-8)24-15-14(21)13(20)12(19)11(7-18)25-15/h4-6,11-16,18-21H,7H2,1-3H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" -"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","2-Hydroxyphenyl-DMST-glucoside","","","N,N-dimethyl-N?-[[2-(YA-D-glucopyranosyl)-4-methyl]phenyl]sulfamide","Not in list","C15H24N2O8S","CN(C)S(=O)(=O)Nc2ccc(C)cc2OC1OC(CO)C(O)C(O)C1O","InChI=1/C15H24N2O8S/c1-8-4-5-9(16-26(22,23)17(2)3)10(6-8)24-15-14(21)13(20)12(19)11(7-18)25-15/h4-6,11-16,18-21H,7H2,1-3H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" -"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","2-Hydroxyphenyl-DMST-glucoside","","","N,N-dimethyl-N?-[[2-(YA-D-glucopyranosyl)-4-methyl]phenyl]sulfamide","Not in list","C15H24N2O8S","CN(C)S(=O)(=O)Nc2ccc(C)cc2OC1OC(CO)C(O)C(O)C1O","InChI=1/C15H24N2O8S/c1-8-4-5-9(16-26(22,23)17(2)3)10(6-8)24-15-14(21)13(20)12(19)11(7-18)25-15/h4-6,11-16,18-21H,7H2,1-3H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" -"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","2-Hydroxyphenyl-DMST-glucoside","","","N,N-dimethyl-N?-[[2-(YA-D-glucopyranosyl)-4-methyl]phenyl]sulfamide","Not in list","C15H24N2O8S","CN(C)S(=O)(=O)Nc2ccc(C)cc2OC1OC(CO)C(O)C(O)C1O","InChI=1/C15H24N2O8S/c1-8-4-5-9(16-26(22,23)17(2)3)10(6-8)24-15-14(21)13(20)12(19)11(7-18)25-15/h4-6,11-16,18-21H,7H2,1-3H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" -"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","2-Hydroxyphenyl-DMST-glucoside","","","N,N-dimethyl-N?-[[2-(YA-D-glucopyranosyl)-4-methyl]phenyl]sulfamide","Not in list","C15H24N2O8S","CN(C)S(=O)(=O)Nc2ccc(C)cc2OC1OC(CO)C(O)C(O)C1O","InChI=1/C15H24N2O8S/c1-8-4-5-9(16-26(22,23)17(2)3)10(6-8)24-15-14(21)13(20)12(19)11(7-18)25-15/h4-6,11-16,18-21H,7H2,1-3H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" -"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","2-Hydroxyphenyl-DMST-glucoside","","","N,N-dimethyl-N?-[[2-(YA-D-glucopyranosyl)-4-methyl]phenyl]sulfamide","Not in list","C15H24N2O8S","CN(C)S(=O)(=O)Nc2ccc(C)cc2OC1OC(CO)C(O)C(O)C1O","InChI=1/C15H24N2O8S/c1-8-4-5-9(16-26(22,23)17(2)3)10(6-8)24-15-14(21)13(20)12(19)11(7-18)25-15/h4-6,11-16,18-21H,7H2,1-3H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" +"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST","","","N'-[4-(hydroxymethyl)phenyl]-N,N-dimethylsulfamide","Not in list","C9H14N2O3S","O=S(=O)(Nc1ccc(cc1)CO)N(C)C","InChI=1/C9H14N2O3S/c1-11(2)15(13,14)10-9-5-3-8(7-12)4-6-9/h3-6,10,12H,7H2,1-2H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" +"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST","","","N'-[4-(hydroxymethyl)phenyl]-N,N-dimethylsulfamide","Not in list","C9H14N2O3S","O=S(=O)(Nc1ccc(cc1)CO)N(C)C","InChI=1/C9H14N2O3S/c1-11(2)15(13,14)10-9-5-3-8(7-12)4-6-9/h3-6,10,12H,7H2,1-2H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" +"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST","","","N'-[4-(hydroxymethyl)phenyl]-N,N-dimethylsulfamide","Not in list","C9H14N2O3S","O=S(=O)(Nc1ccc(cc1)CO)N(C)C","InChI=1/C9H14N2O3S/c1-11(2)15(13,14)10-9-5-3-8(7-12)4-6-9/h3-6,10,12H,7H2,1-2H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" +"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST","","","N'-[4-(hydroxymethyl)phenyl]-N,N-dimethylsulfamide","Not in list","C9H14N2O3S","O=S(=O)(Nc1ccc(cc1)CO)N(C)C","InChI=1/C9H14N2O3S/c1-11(2)15(13,14)10-9-5-3-8(7-12)4-6-9/h3-6,10,12H,7H2,1-2H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" +"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST","","","N'-[4-(hydroxymethyl)phenyl]-N,N-dimethylsulfamide","Not in list","C9H14N2O3S","O=S(=O)(Nc1ccc(cc1)CO)N(C)C","InChI=1/C9H14N2O3S/c1-11(2)15(13,14)10-9-5-3-8(7-12)4-6-9/h3-6,10,12H,7H2,1-2H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" +"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST","","","N'-[4-(hydroxymethyl)phenyl]-N,N-dimethylsulfamide","Not in list","C9H14N2O3S","O=S(=O)(Nc1ccc(cc1)CO)N(C)C","InChI=1/C9H14N2O3S/c1-11(2)15(13,14)10-9-5-3-8(7-12)4-6-9/h3-6,10,12H,7H2,1-2H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" +"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST","","","N'-[4-(hydroxymethyl)phenyl]-N,N-dimethylsulfamide","Not in list","C9H14N2O3S","O=S(=O)(Nc1ccc(cc1)CO)N(C)C","InChI=1/C9H14N2O3S/c1-11(2)15(13,14)10-9-5-3-8(7-12)4-6-9/h3-6,10,12H,7H2,1-2H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" +"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST","","","N'-[4-(hydroxymethyl)phenyl]-N,N-dimethylsulfamide","Not in list","C9H14N2O3S","O=S(=O)(Nc1ccc(cc1)CO)N(C)C","InChI=1/C9H14N2O3S/c1-11(2)15(13,14)10-9-5-3-8(7-12)4-6-9/h3-6,10,12H,7H2,1-2H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" +"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST-glucoside","","","N,N-dimethyl-N?-[(4-(ñ-D-glucopyranosyl)-methylphenyl]sulfamide","Not in list","C16H26N2O8S","CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2","InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" +"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST-glucoside","","","N,N-dimethyl-N?-[(4-(ñ-D-glucopyranosyl)-methylphenyl]sulfamide","Not in list","C16H26N2O8S","CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2","InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" +"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST-glucoside","","","N,N-dimethyl-N?-[(4-(ñ-D-glucopyranosyl)-methylphenyl]sulfamide","Not in list","C16H26N2O8S","CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2","InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" +"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST-glucoside","","","N,N-dimethyl-N?-[(4-(ñ-D-glucopyranosyl)-methylphenyl]sulfamide","Not in list","C16H26N2O8S","CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2","InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" +"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST-glucoside","","","N,N-dimethyl-N?-[(4-(ñ-D-glucopyranosyl)-methylphenyl]sulfamide","Not in list","C16H26N2O8S","CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2","InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" +"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST-glucoside","","","N,N-dimethyl-N?-[(4-(ñ-D-glucopyranosyl)-methylphenyl]sulfamide","Not in list","C16H26N2O8S","CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2","InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" +"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST-glucoside","","","N,N-dimethyl-N?-[(4-(ñ-D-glucopyranosyl)-methylphenyl]sulfamide","Not in list","C16H26N2O8S","CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2","InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" +"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST-glucoside","","","N,N-dimethyl-N?-[(4-(ñ-D-glucopyranosyl)-methylphenyl]sulfamide","Not in list","C16H26N2O8S","CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2","InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" +"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","2-Hydroxyphenyl-DMST-glucoside","","","N,N-dimethyl-N?-[[2-(ñ-D-glucopyranosyl)-4-methyl]phenyl]sulfamide","Not in list","C15H24N2O8S","CN(C)S(=O)(=O)Nc2ccc(C)cc2OC1OC(CO)C(O)C(O)C1O","InChI=1/C15H24N2O8S/c1-8-4-5-9(16-26(22,23)17(2)3)10(6-8)24-15-14(21)13(20)12(19)11(7-18)25-15/h4-6,11-16,18-21H,7H2,1-3H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" +"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","2-Hydroxyphenyl-DMST-glucoside","","","N,N-dimethyl-N?-[[2-(ñ-D-glucopyranosyl)-4-methyl]phenyl]sulfamide","Not in list","C15H24N2O8S","CN(C)S(=O)(=O)Nc2ccc(C)cc2OC1OC(CO)C(O)C(O)C1O","InChI=1/C15H24N2O8S/c1-8-4-5-9(16-26(22,23)17(2)3)10(6-8)24-15-14(21)13(20)12(19)11(7-18)25-15/h4-6,11-16,18-21H,7H2,1-3H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" +"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","2-Hydroxyphenyl-DMST-glucoside","","","N,N-dimethyl-N?-[[2-(ñ-D-glucopyranosyl)-4-methyl]phenyl]sulfamide","Not in list","C15H24N2O8S","CN(C)S(=O)(=O)Nc2ccc(C)cc2OC1OC(CO)C(O)C(O)C1O","InChI=1/C15H24N2O8S/c1-8-4-5-9(16-26(22,23)17(2)3)10(6-8)24-15-14(21)13(20)12(19)11(7-18)25-15/h4-6,11-16,18-21H,7H2,1-3H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" +"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","2-Hydroxyphenyl-DMST-glucoside","","","N,N-dimethyl-N?-[[2-(ñ-D-glucopyranosyl)-4-methyl]phenyl]sulfamide","Not in list","C15H24N2O8S","CN(C)S(=O)(=O)Nc2ccc(C)cc2OC1OC(CO)C(O)C(O)C1O","InChI=1/C15H24N2O8S/c1-8-4-5-9(16-26(22,23)17(2)3)10(6-8)24-15-14(21)13(20)12(19)11(7-18)25-15/h4-6,11-16,18-21H,7H2,1-3H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" +"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","2-Hydroxyphenyl-DMST-glucoside","","","N,N-dimethyl-N?-[[2-(ñ-D-glucopyranosyl)-4-methyl]phenyl]sulfamide","Not in list","C15H24N2O8S","CN(C)S(=O)(=O)Nc2ccc(C)cc2OC1OC(CO)C(O)C(O)C1O","InChI=1/C15H24N2O8S/c1-8-4-5-9(16-26(22,23)17(2)3)10(6-8)24-15-14(21)13(20)12(19)11(7-18)25-15/h4-6,11-16,18-21H,7H2,1-3H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" +"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","2-Hydroxyphenyl-DMST-glucoside","","","N,N-dimethyl-N?-[[2-(ñ-D-glucopyranosyl)-4-methyl]phenyl]sulfamide","Not in list","C15H24N2O8S","CN(C)S(=O)(=O)Nc2ccc(C)cc2OC1OC(CO)C(O)C(O)C1O","InChI=1/C15H24N2O8S/c1-8-4-5-9(16-26(22,23)17(2)3)10(6-8)24-15-14(21)13(20)12(19)11(7-18)25-15/h4-6,11-16,18-21H,7H2,1-3H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" +"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","2-Hydroxyphenyl-DMST-glucoside","","","N,N-dimethyl-N?-[[2-(ñ-D-glucopyranosyl)-4-methyl]phenyl]sulfamide","Not in list","C15H24N2O8S","CN(C)S(=O)(=O)Nc2ccc(C)cc2OC1OC(CO)C(O)C(O)C1O","InChI=1/C15H24N2O8S/c1-8-4-5-9(16-26(22,23)17(2)3)10(6-8)24-15-14(21)13(20)12(19)11(7-18)25-15/h4-6,11-16,18-21H,7H2,1-3H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" +"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","2-Hydroxyphenyl-DMST-glucoside","","","N,N-dimethyl-N?-[[2-(ñ-D-glucopyranosyl)-4-methyl]phenyl]sulfamide","Not in list","C15H24N2O8S","CN(C)S(=O)(=O)Nc2ccc(C)cc2OC1OC(CO)C(O)C(O)C1O","InChI=1/C15H24N2O8S/c1-8-4-5-9(16-26(22,23)17(2)3)10(6-8)24-15-14(21)13(20)12(19)11(7-18)25-15/h4-6,11-16,18-21H,7H2,1-3H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" "Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","2-Hydroxyphenyl-DMST","","","N,N-dimethyl-N?-[(2-hydroxy-4-methyl)-phenyl]sulfamide","Not in list","C9H14N2O3S","Oc1cc(C)ccc1NS(=O)(=O)N(C)C","InChI=1/C9H14N2O3S/c1-7-4-5-8(9(12)6-7)10-15(13,14)11(2)3/h4-6,10,12H,1-3H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" "Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","2-Hydroxyphenyl-DMST","","","N,N-dimethyl-N?-[(2-hydroxy-4-methyl)-phenyl]sulfamide","Not in list","C9H14N2O3S","Oc1cc(C)ccc1NS(=O)(=O)N(C)C","InChI=1/C9H14N2O3S/c1-7-4-5-8(9(12)6-7)10-15(13,14)11(2)3/h4-6,10,12H,1-3H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" "Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","2-Hydroxyphenyl-DMST","","","N,N-dimethyl-N?-[(2-hydroxy-4-methyl)-phenyl]sulfamide","Not in list","C9H14N2O3S","Oc1cc(C)ccc1NS(=O)(=O)N(C)C","InChI=1/C9H14N2O3S/c1-7-4-5-8(9(12)6-7)10-15(13,14)11(2)3/h4-6,10,12H,1-3H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" @@ -16135,31 +16135,31 @@ ethyl carbonate","Not in list","C21H27NO5","CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3 "Fenpropimorph","266-719-9","67564-91-4","single chemical entity","Component is identical to the substance","Fenpropimorph","266-719-9","67564-91-4","(2R,6S)-4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine","Fenpropimorph","C20H33NO","CC(C)(C)C(C=C2)=CC=C2CC(C)CN1C[C@@H](C)O[C@@H](C)C1","InChI=1S/C20H33NO/c1-15(12-21-13-16(2)22-17(3)14-21)11-18-7-9-19(10-8-18)20(4,5)6/h7-10,15-17H,11-14H2,1-6H3/t15?,16-,17+","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","NMRI","5","Male/Female","intraperitoneal","48","h","yes","not applicable","Negative","","indirect evidence-systemic toxicity","RMS: Germany","Fenpropimorph","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropimorph","39658","2008","doi:10.2903/j.efsa.2008.144r" "Fenpropimorph","266-719-9","67564-91-4","single chemical entity","Component is identical to the substance","Fenpropimorph","266-719-9","67564-91-4","(2R,6S)-4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine","Fenpropimorph","C20H33NO","CC(C)(C)C(C=C2)=CC=C2CC(C)CN1C[C@@H](C)O[C@@H](C)C1","InChI=1S/C20H33NO/c1-15(12-21-13-16(2)22-17(3)14-21)11-18-7-9-19(10-8-18)20(4,5)6/h7-10,15-17H,11-14H2,1-6H3/t15?,16-,17+","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","NMRI","5","Male/Female","intraperitoneal","24","h","yes","not applicable","Negative","","indirect evidence-systemic toxicity","RMS: Germany","Fenpropimorph","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropimorph","39658","2008","doi:10.2903/j.efsa.2008.144r" "Fenpropimorph","266-719-9","67564-91-4","single chemical entity","Component is identical to the substance","Fenpropimorph","266-719-9","67564-91-4","(2R,6S)-4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine","Fenpropimorph","C20H33NO","CC(C)(C)C(C=C2)=CC=C2CC(C)CN1C[C@@H](C)O[C@@H](C)C1","InChI=1S/C20H33NO/c1-15(12-21-13-16(2)22-17(3)14-21)11-18-7-9-19(10-8-18)20(4,5)6/h7-10,15-17H,11-14H2,1-6H3/t15?,16-,17+","organic","compound","Other","Other","chromosome aberration","dominant lethal assay","in vivo","According to","OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)","No","Acceptable","House mouse (as animal)","NMRI","40","Male","intraperitoneal","18","D","yes, concurrent vehicle","not applicable","Negative","","","RMS: Germany","Fenpropimorph","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropimorph","39658","2008","doi:10.2903/j.efsa.2008.144r" -"Flubendiamide","","272451-65-7","single chemical entity","Component is identical to the substance","Flubendiamide","","272451-65-7","3-iodo-N?-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide","Flubendiamide","C23H22F7IN2O4S","CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C","InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" -"Flubendiamide","","272451-65-7","single chemical entity","Component is identical to the substance","Flubendiamide","","272451-65-7","3-iodo-N?-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide","Flubendiamide","C23H22F7IN2O4S","CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C","InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" -"Flubendiamide","","272451-65-7","single chemical entity","Component is identical to the substance","Flubendiamide","","272451-65-7","3-iodo-N?-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide","Flubendiamide","C23H22F7IN2O4S","CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C","InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" -"Flubendiamide","","272451-65-7","single chemical entity","Component is identical to the substance","Flubendiamide","","272451-65-7","3-iodo-N?-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide","Flubendiamide","C23H22F7IN2O4S","CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C","InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" -"Flubendiamide","","272451-65-7","single chemical entity","Component is identical to the substance","Flubendiamide","","272451-65-7","3-iodo-N?-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide","Flubendiamide","C23H22F7IN2O4S","CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C","InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" -"Flubendiamide","","272451-65-7","single chemical entity","Component is identical to the substance","Flubendiamide","","272451-65-7","3-iodo-N?-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide","Flubendiamide","C23H22F7IN2O4S","CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C","InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" -"Flubendiamide","","272451-65-7","single chemical entity","Component is identical to the substance","Flubendiamide","","272451-65-7","3-iodo-N?-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide","Flubendiamide","C23H22F7IN2O4S","CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C","InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" -"Flubendiamide","","272451-65-7","single chemical entity","Component is identical to the substance","Flubendiamide","","272451-65-7","3-iodo-N?-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide","Flubendiamide","C23H22F7IN2O4S","CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C","InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" -"Flubendiamide","","272451-65-7","single chemical entity","Component is identical to the substance","Flubendiamide","","272451-65-7","3-iodo-N?-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide","Flubendiamide","C23H22F7IN2O4S","CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C","InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" -"Flubendiamide","","272451-65-7","single chemical entity","Component is identical to the substance","Flubendiamide","","272451-65-7","3-iodo-N?-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide","Flubendiamide","C23H22F7IN2O4S","CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C","InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" -"Flubendiamide","","272451-65-7","single chemical entity","Component is identical to the substance","Flubendiamide","","272451-65-7","3-iodo-N?-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide","Flubendiamide","C23H22F7IN2O4S","CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C","InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","lung fibroblasts (V79)","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" -"Flubendiamide","","272451-65-7","single chemical entity","Component is identical to the substance","Flubendiamide","","272451-65-7","3-iodo-N?-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide","Flubendiamide","C23H22F7IN2O4S","CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C","InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","lung fibroblasts (V79)","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" -"Flubendiamide","","272451-65-7","single chemical entity","Component is identical to the substance","Flubendiamide","","272451-65-7","3-iodo-N?-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide","Flubendiamide","C23H22F7IN2O4S","CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C","InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" -"Flubendiamide","","272451-65-7","single chemical entity","Component is identical to the substance","Flubendiamide","","272451-65-7","3-iodo-N?-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide","Flubendiamide","C23H22F7IN2O4S","CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C","InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" -"Flubendiamide","","272451-65-7","single chemical entity","Component is identical to the substance","Flubendiamide","","272451-65-7","3-iodo-N?-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide","Flubendiamide","C23H22F7IN2O4S","CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C","InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","NMRI","5","Male","intraperitoneal","24","h","yes","not applicable","Negative","","direct evidence-cytotoxicity$indirect evidence-systemic toxicity","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" -"Flubendiamide","","272451-65-7","single chemical entity","Component is a metabolite of the substance","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N?-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","","","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N?-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","Not in list","C23H23F7N2O4S","Cc2cc(ccc2NC(=O)c1ccccc1C(=O)NC(C)(C)CS(C)(=O)=O)C(F)(C(F)(F)F)C(F)(F)F","InChI=1/C23H23F7N2O4S/c1-13-11-14(21(24,22(25,26)27)23(28,29)30)9-10-17(13)31-18(33)15-7-5-6-8-16(15)19(34)32-20(2,3)12-37(4,35)36/h5-11H,12H2,1-4H3,(H,31,33)(H,32,34)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" -"Flubendiamide","","272451-65-7","single chemical entity","Component is a metabolite of the substance","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N?-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","","","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N?-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","Not in list","C23H23F7N2O4S","Cc2cc(ccc2NC(=O)c1ccccc1C(=O)NC(C)(C)CS(C)(=O)=O)C(F)(C(F)(F)F)C(F)(F)F","InChI=1/C23H23F7N2O4S/c1-13-11-14(21(24,22(25,26)27)23(28,29)30)9-10-17(13)31-18(33)15-7-5-6-8-16(15)19(34)32-20(2,3)12-37(4,35)36/h5-11H,12H2,1-4H3,(H,31,33)(H,32,34)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" -"Flubendiamide","","272451-65-7","single chemical entity","Component is a metabolite of the substance","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N?-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","","","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N?-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","Not in list","C23H23F7N2O4S","Cc2cc(ccc2NC(=O)c1ccccc1C(=O)NC(C)(C)CS(C)(=O)=O)C(F)(C(F)(F)F)C(F)(F)F","InChI=1/C23H23F7N2O4S/c1-13-11-14(21(24,22(25,26)27)23(28,29)30)9-10-17(13)31-18(33)15-7-5-6-8-16(15)19(34)32-20(2,3)12-37(4,35)36/h5-11H,12H2,1-4H3,(H,31,33)(H,32,34)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" -"Flubendiamide","","272451-65-7","single chemical entity","Component is a metabolite of the substance","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N?-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","","","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N?-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","Not in list","C23H23F7N2O4S","Cc2cc(ccc2NC(=O)c1ccccc1C(=O)NC(C)(C)CS(C)(=O)=O)C(F)(C(F)(F)F)C(F)(F)F","InChI=1/C23H23F7N2O4S/c1-13-11-14(21(24,22(25,26)27)23(28,29)30)9-10-17(13)31-18(33)15-7-5-6-8-16(15)19(34)32-20(2,3)12-37(4,35)36/h5-11H,12H2,1-4H3,(H,31,33)(H,32,34)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" -"Flubendiamide","","272451-65-7","single chemical entity","Component is a metabolite of the substance","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N?-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","","","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N?-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","Not in list","C23H23F7N2O4S","Cc2cc(ccc2NC(=O)c1ccccc1C(=O)NC(C)(C)CS(C)(=O)=O)C(F)(C(F)(F)F)C(F)(F)F","InChI=1/C23H23F7N2O4S/c1-13-11-14(21(24,22(25,26)27)23(28,29)30)9-10-17(13)31-18(33)15-7-5-6-8-16(15)19(34)32-20(2,3)12-37(4,35)36/h5-11H,12H2,1-4H3,(H,31,33)(H,32,34)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" -"Flubendiamide","","272451-65-7","single chemical entity","Component is a metabolite of the substance","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N?-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","","","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N?-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","Not in list","C23H23F7N2O4S","Cc2cc(ccc2NC(=O)c1ccccc1C(=O)NC(C)(C)CS(C)(=O)=O)C(F)(C(F)(F)F)C(F)(F)F","InChI=1/C23H23F7N2O4S/c1-13-11-14(21(24,22(25,26)27)23(28,29)30)9-10-17(13)31-18(33)15-7-5-6-8-16(15)19(34)32-20(2,3)12-37(4,35)36/h5-11H,12H2,1-4H3,(H,31,33)(H,32,34)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" -"Flubendiamide","","272451-65-7","single chemical entity","Component is a metabolite of the substance","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N?-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","","","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N?-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","Not in list","C23H23F7N2O4S","Cc2cc(ccc2NC(=O)c1ccccc1C(=O)NC(C)(C)CS(C)(=O)=O)C(F)(C(F)(F)F)C(F)(F)F","InChI=1/C23H23F7N2O4S/c1-13-11-14(21(24,22(25,26)27)23(28,29)30)9-10-17(13)31-18(33)15-7-5-6-8-16(15)19(34)32-20(2,3)12-37(4,35)36/h5-11H,12H2,1-4H3,(H,31,33)(H,32,34)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" -"Flubendiamide","","272451-65-7","single chemical entity","Component is a metabolite of the substance","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N?-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","","","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N?-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","Not in list","C23H23F7N2O4S","Cc2cc(ccc2NC(=O)c1ccccc1C(=O)NC(C)(C)CS(C)(=O)=O)C(F)(C(F)(F)F)C(F)(F)F","InChI=1/C23H23F7N2O4S/c1-13-11-14(21(24,22(25,26)27)23(28,29)30)9-10-17(13)31-18(33)15-7-5-6-8-16(15)19(34)32-20(2,3)12-37(4,35)36/h5-11H,12H2,1-4H3,(H,31,33)(H,32,34)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" -"Flubendiamide","","272451-65-7","single chemical entity","Component is a metabolite of the substance","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N?-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","","","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N?-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","Not in list","C23H23F7N2O4S","Cc2cc(ccc2NC(=O)c1ccccc1C(=O)NC(C)(C)CS(C)(=O)=O)C(F)(C(F)(F)F)C(F)(F)F","InChI=1/C23H23F7N2O4S/c1-13-11-14(21(24,22(25,26)27)23(28,29)30)9-10-17(13)31-18(33)15-7-5-6-8-16(15)19(34)32-20(2,3)12-37(4,35)36/h5-11H,12H2,1-4H3,(H,31,33)(H,32,34)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" -"Flubendiamide","","272451-65-7","single chemical entity","Component is a metabolite of the substance","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N?-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","","","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N?-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","Not in list","C23H23F7N2O4S","Cc2cc(ccc2NC(=O)c1ccccc1C(=O)NC(C)(C)CS(C)(=O)=O)C(F)(C(F)(F)F)C(F)(F)F","InChI=1/C23H23F7N2O4S/c1-13-11-14(21(24,22(25,26)27)23(28,29)30)9-10-17(13)31-18(33)15-7-5-6-8-16(15)19(34)32-20(2,3)12-37(4,35)36/h5-11H,12H2,1-4H3,(H,31,33)(H,32,34)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" +"Flubendiamide","","272451-65-7","single chemical entity","Component is identical to the substance","Flubendiamide","","272451-65-7","3-iodo-N'-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide","Flubendiamide","C23H22F7IN2O4S","CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C","InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" +"Flubendiamide","","272451-65-7","single chemical entity","Component is identical to the substance","Flubendiamide","","272451-65-7","3-iodo-N'-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide","Flubendiamide","C23H22F7IN2O4S","CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C","InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" +"Flubendiamide","","272451-65-7","single chemical entity","Component is identical to the substance","Flubendiamide","","272451-65-7","3-iodo-N'-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide","Flubendiamide","C23H22F7IN2O4S","CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C","InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" +"Flubendiamide","","272451-65-7","single chemical entity","Component is identical to the substance","Flubendiamide","","272451-65-7","3-iodo-N'-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide","Flubendiamide","C23H22F7IN2O4S","CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C","InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" +"Flubendiamide","","272451-65-7","single chemical entity","Component is identical to the substance","Flubendiamide","","272451-65-7","3-iodo-N'-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide","Flubendiamide","C23H22F7IN2O4S","CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C","InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" +"Flubendiamide","","272451-65-7","single chemical entity","Component is identical to the substance","Flubendiamide","","272451-65-7","3-iodo-N'-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide","Flubendiamide","C23H22F7IN2O4S","CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C","InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" +"Flubendiamide","","272451-65-7","single chemical entity","Component is identical to the substance","Flubendiamide","","272451-65-7","3-iodo-N'-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide","Flubendiamide","C23H22F7IN2O4S","CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C","InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" +"Flubendiamide","","272451-65-7","single chemical entity","Component is identical to the substance","Flubendiamide","","272451-65-7","3-iodo-N'-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide","Flubendiamide","C23H22F7IN2O4S","CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C","InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" +"Flubendiamide","","272451-65-7","single chemical entity","Component is identical to the substance","Flubendiamide","","272451-65-7","3-iodo-N'-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide","Flubendiamide","C23H22F7IN2O4S","CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C","InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" +"Flubendiamide","","272451-65-7","single chemical entity","Component is identical to the substance","Flubendiamide","","272451-65-7","3-iodo-N'-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide","Flubendiamide","C23H22F7IN2O4S","CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C","InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" +"Flubendiamide","","272451-65-7","single chemical entity","Component is identical to the substance","Flubendiamide","","272451-65-7","3-iodo-N'-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide","Flubendiamide","C23H22F7IN2O4S","CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C","InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","lung fibroblasts (V79)","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" +"Flubendiamide","","272451-65-7","single chemical entity","Component is identical to the substance","Flubendiamide","","272451-65-7","3-iodo-N'-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide","Flubendiamide","C23H22F7IN2O4S","CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C","InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","lung fibroblasts (V79)","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" +"Flubendiamide","","272451-65-7","single chemical entity","Component is identical to the substance","Flubendiamide","","272451-65-7","3-iodo-N'-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide","Flubendiamide","C23H22F7IN2O4S","CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C","InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" +"Flubendiamide","","272451-65-7","single chemical entity","Component is identical to the substance","Flubendiamide","","272451-65-7","3-iodo-N'-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide","Flubendiamide","C23H22F7IN2O4S","CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C","InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" +"Flubendiamide","","272451-65-7","single chemical entity","Component is identical to the substance","Flubendiamide","","272451-65-7","3-iodo-N'-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide","Flubendiamide","C23H22F7IN2O4S","CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C","InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","NMRI","5","Male","intraperitoneal","24","h","yes","not applicable","Negative","","direct evidence-cytotoxicity$indirect evidence-systemic toxicity","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" +"Flubendiamide","","272451-65-7","single chemical entity","Component is a metabolite of the substance","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","","","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","Not in list","C23H23F7N2O4S","Cc2cc(ccc2NC(=O)c1ccccc1C(=O)NC(C)(C)CS(C)(=O)=O)C(F)(C(F)(F)F)C(F)(F)F","InChI=1/C23H23F7N2O4S/c1-13-11-14(21(24,22(25,26)27)23(28,29)30)9-10-17(13)31-18(33)15-7-5-6-8-16(15)19(34)32-20(2,3)12-37(4,35)36/h5-11H,12H2,1-4H3,(H,31,33)(H,32,34)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" +"Flubendiamide","","272451-65-7","single chemical entity","Component is a metabolite of the substance","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","","","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","Not in list","C23H23F7N2O4S","Cc2cc(ccc2NC(=O)c1ccccc1C(=O)NC(C)(C)CS(C)(=O)=O)C(F)(C(F)(F)F)C(F)(F)F","InChI=1/C23H23F7N2O4S/c1-13-11-14(21(24,22(25,26)27)23(28,29)30)9-10-17(13)31-18(33)15-7-5-6-8-16(15)19(34)32-20(2,3)12-37(4,35)36/h5-11H,12H2,1-4H3,(H,31,33)(H,32,34)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" +"Flubendiamide","","272451-65-7","single chemical entity","Component is a metabolite of the substance","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","","","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","Not in list","C23H23F7N2O4S","Cc2cc(ccc2NC(=O)c1ccccc1C(=O)NC(C)(C)CS(C)(=O)=O)C(F)(C(F)(F)F)C(F)(F)F","InChI=1/C23H23F7N2O4S/c1-13-11-14(21(24,22(25,26)27)23(28,29)30)9-10-17(13)31-18(33)15-7-5-6-8-16(15)19(34)32-20(2,3)12-37(4,35)36/h5-11H,12H2,1-4H3,(H,31,33)(H,32,34)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" +"Flubendiamide","","272451-65-7","single chemical entity","Component is a metabolite of the substance","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","","","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","Not in list","C23H23F7N2O4S","Cc2cc(ccc2NC(=O)c1ccccc1C(=O)NC(C)(C)CS(C)(=O)=O)C(F)(C(F)(F)F)C(F)(F)F","InChI=1/C23H23F7N2O4S/c1-13-11-14(21(24,22(25,26)27)23(28,29)30)9-10-17(13)31-18(33)15-7-5-6-8-16(15)19(34)32-20(2,3)12-37(4,35)36/h5-11H,12H2,1-4H3,(H,31,33)(H,32,34)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" +"Flubendiamide","","272451-65-7","single chemical entity","Component is a metabolite of the substance","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","","","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","Not in list","C23H23F7N2O4S","Cc2cc(ccc2NC(=O)c1ccccc1C(=O)NC(C)(C)CS(C)(=O)=O)C(F)(C(F)(F)F)C(F)(F)F","InChI=1/C23H23F7N2O4S/c1-13-11-14(21(24,22(25,26)27)23(28,29)30)9-10-17(13)31-18(33)15-7-5-6-8-16(15)19(34)32-20(2,3)12-37(4,35)36/h5-11H,12H2,1-4H3,(H,31,33)(H,32,34)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" +"Flubendiamide","","272451-65-7","single chemical entity","Component is a metabolite of the substance","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","","","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","Not in list","C23H23F7N2O4S","Cc2cc(ccc2NC(=O)c1ccccc1C(=O)NC(C)(C)CS(C)(=O)=O)C(F)(C(F)(F)F)C(F)(F)F","InChI=1/C23H23F7N2O4S/c1-13-11-14(21(24,22(25,26)27)23(28,29)30)9-10-17(13)31-18(33)15-7-5-6-8-16(15)19(34)32-20(2,3)12-37(4,35)36/h5-11H,12H2,1-4H3,(H,31,33)(H,32,34)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" +"Flubendiamide","","272451-65-7","single chemical entity","Component is a metabolite of the substance","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","","","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","Not in list","C23H23F7N2O4S","Cc2cc(ccc2NC(=O)c1ccccc1C(=O)NC(C)(C)CS(C)(=O)=O)C(F)(C(F)(F)F)C(F)(F)F","InChI=1/C23H23F7N2O4S/c1-13-11-14(21(24,22(25,26)27)23(28,29)30)9-10-17(13)31-18(33)15-7-5-6-8-16(15)19(34)32-20(2,3)12-37(4,35)36/h5-11H,12H2,1-4H3,(H,31,33)(H,32,34)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" +"Flubendiamide","","272451-65-7","single chemical entity","Component is a metabolite of the substance","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","","","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","Not in list","C23H23F7N2O4S","Cc2cc(ccc2NC(=O)c1ccccc1C(=O)NC(C)(C)CS(C)(=O)=O)C(F)(C(F)(F)F)C(F)(F)F","InChI=1/C23H23F7N2O4S/c1-13-11-14(21(24,22(25,26)27)23(28,29)30)9-10-17(13)31-18(33)15-7-5-6-8-16(15)19(34)32-20(2,3)12-37(4,35)36/h5-11H,12H2,1-4H3,(H,31,33)(H,32,34)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" +"Flubendiamide","","272451-65-7","single chemical entity","Component is a metabolite of the substance","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","","","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","Not in list","C23H23F7N2O4S","Cc2cc(ccc2NC(=O)c1ccccc1C(=O)NC(C)(C)CS(C)(=O)=O)C(F)(C(F)(F)F)C(F)(F)F","InChI=1/C23H23F7N2O4S/c1-13-11-14(21(24,22(25,26)27)23(28,29)30)9-10-17(13)31-18(33)15-7-5-6-8-16(15)19(34)32-20(2,3)12-37(4,35)36/h5-11H,12H2,1-4H3,(H,31,33)(H,32,34)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" +"Flubendiamide","","272451-65-7","single chemical entity","Component is a metabolite of the substance","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","","","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","Not in list","C23H23F7N2O4S","Cc2cc(ccc2NC(=O)c1ccccc1C(=O)NC(C)(C)CS(C)(=O)=O)C(F)(C(F)(F)F)C(F)(F)F","InChI=1/C23H23F7N2O4S/c1-13-11-14(21(24,22(25,26)27)23(28,29)30)9-10-17(13)31-18(33)15-7-5-6-8-16(15)19(34)32-20(2,3)12-37(4,35)36/h5-11H,12H2,1-4H3,(H,31,33)(H,32,34)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" "Flubendiamide","","272451-65-7","single chemical entity","Component is a metabolite of the substance","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-3-hydroxy-N2-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","","","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-3-hydroxy-N2-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","Not in list","C23H23F7N2O5S","O=C(NC(C)(C)CS(C)(=O)=O)c1c(cccc1O)C(=O)Nc2ccc(cc2C)C(F)(C(F)(F)F)C(F)(F)F","InChI=1/C23H23F7N2O5S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-15(12)31-18(34)14-6-5-7-16(33)17(14)19(35)32-20(2,3)11-38(4,36)37/h5-10,33H,11H2,1-4H3,(H,31,34)(H,32,35)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" "Flubendiamide","","272451-65-7","single chemical entity","Component is a metabolite of the substance","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-3-hydroxy-N2-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","","","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-3-hydroxy-N2-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","Not in list","C23H23F7N2O5S","O=C(NC(C)(C)CS(C)(=O)=O)c1c(cccc1O)C(=O)Nc2ccc(cc2C)C(F)(C(F)(F)F)C(F)(F)F","InChI=1/C23H23F7N2O5S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-15(12)31-18(34)14-6-5-7-16(33)17(14)19(35)32-20(2,3)11-38(4,36)37/h5-10,33H,11H2,1-4H3,(H,31,34)(H,32,35)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" "Flubendiamide","","272451-65-7","single chemical entity","Component is a metabolite of the substance","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-3-hydroxy-N2-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","","","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-3-hydroxy-N2-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","Not in list","C23H23F7N2O5S","O=C(NC(C)(C)CS(C)(=O)=O)c1c(cccc1O)C(=O)Nc2ccc(cc2C)C(F)(C(F)(F)F)C(F)(F)F","InChI=1/C23H23F7N2O5S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-15(12)31-18(34)14-6-5-7-16(33)17(14)19(35)32-20(2,3)11-38(4,36)37/h5-10,33H,11H2,1-4H3,(H,31,34)(H,32,35)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" @@ -16734,29 +16734,29 @@ ethyl carbonate","Not in list","C21H27NO5","CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3 "Ferric phosphate","233-149-7","10045-86-0","single chemical entity","Component is identical to the substance","Ferric phosphate","233-149-7","10045-86-0","iron(3+);phosphate","Not in list","FePO4","[O-]P(=O)([O-])[O-].[Fe+3]","InChI=1S/Fe.H3O4P/c;1-5(2,3)4/h;(H3,1,2,3,4)/q+3;/p-3","inorganic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany - CoRMS: Poland","Ferric phosphate (Final addendum to Renewal Assessment Report)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance ferric phosphate","42033","2015","doi:10.2903/j.efsa.2015.3973" "Ferric phosphate","233-149-7","10045-86-0","single chemical entity","Component is identical to the substance","Ferric phosphate","233-149-7","10045-86-0","iron(3+);phosphate","Not in list","FePO4","[O-]P(=O)([O-])[O-].[Fe+3]","InChI=1S/Fe.H3O4P/c;1-5(2,3)4/h;(H3,1,2,3,4)/q+3;/p-3","inorganic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","NMRI","10","Male/Female","oral: gavage","48","h","yes","not applicable","Negative","","no evidence","RMS: Germany - CoRMS: Poland","Ferric phosphate (Final addendum to Renewal Assessment Report)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance ferric phosphate","42033","2015","doi:10.2903/j.efsa.2015.3973" "Ferric phosphate","233-149-7","10045-86-0","single chemical entity","Component is identical to the substance","Ferric phosphate","233-149-7","10045-86-0","iron(3+);phosphate","Not in list","FePO4","[O-]P(=O)([O-])[O-].[Fe+3]","InChI=1S/Fe.H3O4P/c;1-5(2,3)4/h;(H3,1,2,3,4)/q+3;/p-3","inorganic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","NMRI","10","Male/Female","oral: gavage","24","h","yes","not applicable","Negative","","no evidence","RMS: Germany - CoRMS: Poland","Ferric phosphate (Final addendum to Renewal Assessment Report)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance ferric phosphate","42033","2015","doi:10.2903/j.efsa.2015.3973" -"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1?-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" -"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1?-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A pKM 101","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" -"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1?-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" -"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1?-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A pKM 101","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" -"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1?-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" -"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1?-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" -"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1?-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" -"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1?-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" -"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1?-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" -"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1?-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" -"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1?-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" -"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1?-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" -"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1?-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" -"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1?-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" -"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1?-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","Equivalent or similar to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","Yes","Acceptable","House mouse (as animal)","lymphoma L5178Y cells","","","Not reported","","","yes","without","Ambiguous","small colonies","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" -"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1?-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","Equivalent or similar to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","Yes","Acceptable","House mouse (as animal)","lymphoma L5178Y cells","","","Not reported","","","yes","with","Ambiguous","small colonies","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" -"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1?-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","Equivalent or similar to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","Yes","Acceptable","House mouse (as animal)","lymphoma L5178Y cells","","","Not reported","","","yes","without","Ambiguous","large colonies","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" -"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1?-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","Equivalent or similar to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","Yes","Acceptable","House mouse (as animal)","lymphoma L5178Y cells","","","Not reported","","","yes","with","Ambiguous","large colonies","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" -"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1?-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","NMRI","12","Male/Female","oral: unspecified","48","h","yes","not applicable","Negative","","no evidence","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" -"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1?-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","NMRI","12","Male/Female","oral: unspecified","24","h","yes","not applicable","Negative","","no evidence","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" -"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1?-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","DNA damage and/or repair","unscheduled DNA synthesis","in vivo","According to","OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)","No","Acceptable","Rat (as animal)","Sprague-Dawley","4","Male","oral: unspecified","16","h","yes","not applicable","Ambiguous","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" -"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1?-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","DNA damage and/or repair","unscheduled DNA synthesis","in vivo","According to","OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)","No","Acceptable","Rat (as animal)","Wistar","4","Male/Female","oral: gavage","16","h","yes, concurrent vehicle","not applicable","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" -"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1?-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","DNA damage and/or repair","unscheduled DNA synthesis","in vivo","According to","OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)","No","Acceptable","Rat (as animal)","Wistar","4","Male/Female","oral: gavage","4","h","yes, concurrent vehicle","not applicable","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" +"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" +"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A pKM 101","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" +"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" +"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A pKM 101","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" +"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" +"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" +"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" +"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" +"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" +"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" +"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" +"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" +"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" +"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" +"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","Equivalent or similar to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","Yes","Acceptable","House mouse (as animal)","lymphoma L5178Y cells","","","Not reported","","","yes","without","Ambiguous","small colonies","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" +"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","Equivalent or similar to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","Yes","Acceptable","House mouse (as animal)","lymphoma L5178Y cells","","","Not reported","","","yes","with","Ambiguous","small colonies","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" +"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","Equivalent or similar to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","Yes","Acceptable","House mouse (as animal)","lymphoma L5178Y cells","","","Not reported","","","yes","without","Ambiguous","large colonies","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" +"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","Equivalent or similar to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","Yes","Acceptable","House mouse (as animal)","lymphoma L5178Y cells","","","Not reported","","","yes","with","Ambiguous","large colonies","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" +"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","NMRI","12","Male/Female","oral: unspecified","48","h","yes","not applicable","Negative","","no evidence","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" +"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","NMRI","12","Male/Female","oral: unspecified","24","h","yes","not applicable","Negative","","no evidence","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" +"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","DNA damage and/or repair","unscheduled DNA synthesis","in vivo","According to","OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)","No","Acceptable","Rat (as animal)","Sprague-Dawley","4","Male","oral: unspecified","16","h","yes","not applicable","Ambiguous","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" +"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","DNA damage and/or repair","unscheduled DNA synthesis","in vivo","According to","OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)","No","Acceptable","Rat (as animal)","Wistar","4","Male/Female","oral: gavage","16","h","yes, concurrent vehicle","not applicable","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" +"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","DNA damage and/or repair","unscheduled DNA synthesis","in vivo","According to","OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)","No","Acceptable","Rat (as animal)","Wistar","4","Male/Female","oral: gavage","4","h","yes, concurrent vehicle","not applicable","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" "Sedaxane","","874967-67-6","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid","","","3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid","Not in list","C5H4F2N2O2","FC(F)c1nncc1C(=O)O","InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" "Sedaxane","","874967-67-6","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid","","","3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid","Not in list","C5H4F2N2O2","FC(F)c1nncc1C(=O)O","InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" "Sedaxane","","874967-67-6","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid","","","3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid","Not in list","C5H4F2N2O2","FC(F)c1nncc1C(=O)O","InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" @@ -17196,40 +17196,40 @@ ethyl carbonate","Not in list","C21H27NO5","CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3 "Carbendazim","234-232-0","10605-21-7","single chemical entity","Component is part of a group but not included in the group assessment","Thiophanate-methyl","245-740-7","23564-05-8","methyl N-[[2-(methoxycarbonylcarbamothioylamino)phenyl]carbamothioyl]carbamate","Thiophanate-methyl","C12H14N4O4S2","COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC","InChI=1S/C12H14N4O4S2/c1-19-11(17)15-9(21)13-7-5-3-4-6-8(7)14-10(22)16-12(18)20-2/h3-6H,1-2H3,(H2,13,15,17,21)(H2,14,16,18,22)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian cell micronucleus test","in vitro","According to","OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Carbendazim, Benomyl, Thiophanate-methyl (Addendum)","2002","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim","40310","2010","doi:10.2903/j.efsa.2010.1598" "Carbendazim","234-232-0","10605-21-7","single chemical entity","Component is part of a group but not included in the group assessment","Thiophanate-methyl","245-740-7","23564-05-8","methyl N-[[2-(methoxycarbonylcarbamothioylamino)phenyl]carbamothioyl]carbamate","Thiophanate-methyl","C12H14N4O4S2","COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC","InChI=1S/C12H14N4O4S2/c1-19-11(17)15-9(21)13-7-5-3-4-6-8(7)14-10(22)16-12(18)20-2/h3-6H,1-2H3,(H2,13,15,17,21)(H2,14,16,18,22)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian cell micronucleus test","in vitro","According to","OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","without","Positive","","","RMS: Germany","Carbendazim, Benomyl, Thiophanate-methyl (Addendum)","2002","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim","40310","2010","doi:10.2903/j.efsa.2010.1598" "Carbendazim","234-232-0","10605-21-7","single chemical entity","Component is part of a group but not included in the group assessment","Thiophanate-methyl","245-740-7","23564-05-8","methyl N-[[2-(methoxycarbonylcarbamothioylamino)phenyl]carbamothioyl]carbamate","Thiophanate-methyl","C12H14N4O4S2","COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC","InChI=1S/C12H14N4O4S2/c1-19-11(17)15-9(21)13-7-5-3-4-6-8(7)14-10(22)16-12(18)20-2/h3-6H,1-2H3,(H2,13,15,17,21)(H2,14,16,18,22)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","other","in vitro","No guideline available","Not reported","Not applicable","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","no data","not applicable","Positive","","","RMS: Germany","Carbendazim, Benomyl, Thiophanate-methyl (Addendum)","2002","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim","40310","2010","doi:10.2903/j.efsa.2010.1598" -"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N?-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N?-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N?-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N?-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N?-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N?-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N?-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N?-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N?-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N?-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N?-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N?-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N?-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N?-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N?-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N?-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N?-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","Equivalent or similar to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","Yes","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N?-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","Equivalent or similar to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","Yes","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N?-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N?-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N?-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","DNA damage and/or repair","DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro","in vitro","According to","OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)","No","Acceptable","Rat (as animal)","hepatocytes","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N?-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","chromosome aberration","chromosome aberration assay","in vivo","According to","OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)","No","Acceptable","Rat (as animal)","Sprague-Dawley","10","Male/Female","oral: gavage","48","h","yes","not applicable","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N?-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","chromosome aberration","chromosome aberration assay","in vivo","According to","OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)","No","Acceptable","Rat (as animal)","Sprague-Dawley","10","Male/Female","oral: gavage","24","h","yes","not applicable","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N?-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","chromosome aberration","chromosome aberration assay","in vivo","According to","OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)","No","Acceptable","Rat (as animal)","Sprague-Dawley","10","Male/Female","oral: gavage","6","h","yes","not applicable","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N?-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","","","N?-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","Not in list","C22H26N2O3","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C","InChI=1/C22H26N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N?-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","","","N?-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","Not in list","C22H26N2O3","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C","InChI=1/C22H26N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N?-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","","","N?-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","Not in list","C22H26N2O3","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C","InChI=1/C22H26N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N?-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","","","N?-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","Not in list","C22H26N2O3","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C","InChI=1/C22H26N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N?-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","","","N?-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","Not in list","C22H26N2O3","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C","InChI=1/C22H26N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N?-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","","","N?-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","Not in list","C22H26N2O3","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C","InChI=1/C22H26N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N?-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","","","N?-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","Not in list","C22H26N2O3","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C","InChI=1/C22H26N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N?-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","","","N?-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","Not in list","C22H26N2O3","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C","InChI=1/C22H26N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N?-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","","","N?-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","Not in list","C22H26N2O3","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C","InChI=1/C22H26N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N?-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","","","N?-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","Not in list","C22H26N2O3","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C","InChI=1/C22H26N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","Equivalent or similar to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","Yes","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","Equivalent or similar to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","Yes","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","DNA damage and/or repair","DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro","in vitro","According to","OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)","No","Acceptable","Rat (as animal)","hepatocytes","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","chromosome aberration","chromosome aberration assay","in vivo","According to","OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)","No","Acceptable","Rat (as animal)","Sprague-Dawley","10","Male/Female","oral: gavage","48","h","yes","not applicable","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","chromosome aberration","chromosome aberration assay","in vivo","According to","OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)","No","Acceptable","Rat (as animal)","Sprague-Dawley","10","Male/Female","oral: gavage","24","h","yes","not applicable","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","chromosome aberration","chromosome aberration assay","in vivo","According to","OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)","No","Acceptable","Rat (as animal)","Sprague-Dawley","10","Male/Female","oral: gavage","6","h","yes","not applicable","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","","","N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","Not in list","C22H26N2O3","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C","InChI=1/C22H26N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","","","N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","Not in list","C22H26N2O3","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C","InChI=1/C22H26N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","","","N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","Not in list","C22H26N2O3","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C","InChI=1/C22H26N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","","","N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","Not in list","C22H26N2O3","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C","InChI=1/C22H26N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","","","N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","Not in list","C22H26N2O3","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C","InChI=1/C22H26N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","","","N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","Not in list","C22H26N2O3","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C","InChI=1/C22H26N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","","","N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","Not in list","C22H26N2O3","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C","InChI=1/C22H26N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","","","N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","Not in list","C22H26N2O3","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C","InChI=1/C22H26N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","","","N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","Not in list","C22H26N2O3","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C","InChI=1/C22H26N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","","","N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","Not in list","C22H26N2O3","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C","InChI=1/C22H26N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" "Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)benzoic acid","","","4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)benzoic acid","Not in list","C21H24N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(O)=O)C(C)(C)C","InChI=1/C21H24N2O4/c1-13-10-14(2)12-17(11-13)19(25)23(21(3,4)5)22-18(24)15-6-8-16(9-7-15)20(26)27/h6-12H,1-5H3,(H,22,24)(H,26,27)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent no treatment","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" "Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)benzoic acid","","","4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)benzoic acid","Not in list","C21H24N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(O)=O)C(C)(C)C","InChI=1/C21H24N2O4/c1-13-10-14(2)12-17(11-13)19(25)23(21(3,4)5)22-18(24)15-6-8-16(9-7-15)20(26)27/h6-12H,1-5H3,(H,22,24)(H,26,27)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent no treatment","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" "Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)benzoic acid","","","4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)benzoic acid","Not in list","C21H24N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(O)=O)C(C)(C)C","InChI=1/C21H24N2O4/c1-13-10-14(2)12-17(11-13)19(25)23(21(3,4)5)22-18(24)15-6-8-16(9-7-15)20(26)27/h6-12H,1-5H3,(H,22,24)(H,26,27)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent no treatment","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" @@ -17240,26 +17240,26 @@ ethyl carbonate","Not in list","C21H27NO5","CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3 "Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)benzoic acid","","","4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)benzoic acid","Not in list","C21H24N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(O)=O)C(C)(C)C","InChI=1/C21H24N2O4/c1-13-10-14(2)12-17(11-13)19(25)23(21(3,4)5)22-18(24)15-6-8-16(9-7-15)20(26)27/h6-12H,1-5H3,(H,22,24)(H,26,27)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent no treatment","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" "Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)benzoic acid","","","4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)benzoic acid","Not in list","C21H24N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(O)=O)C(C)(C)C","InChI=1/C21H24N2O4/c1-13-10-14(2)12-17(11-13)19(25)23(21(3,4)5)22-18(24)15-6-8-16(9-7-15)20(26)27/h6-12H,1-5H3,(H,22,24)(H,26,27)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent no treatment","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" "Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)benzoic acid","","","4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)benzoic acid","Not in list","C21H24N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(O)=O)C(C)(C)C","InChI=1/C21H24N2O4/c1-13-10-14(2)12-17(11-13)19(25)23(21(3,4)5)22-18(24)15-6-8-16(9-7-15)20(26)27/h6-12H,1-5H3,(H,22,24)(H,26,27)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent no treatment","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","","","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","Not in list","C22H28N2O3","Cc1cc(cc(CO)c1)C(=O)N(NC(=O)c2ccc(CC)cc2)C(C)(C)C","InChI=1/C22H28N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-13,25H,6,14H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","","","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","Not in list","C22H28N2O3","Cc1cc(cc(CO)c1)C(=O)N(NC(=O)c2ccc(CC)cc2)C(C)(C)C","InChI=1/C22H28N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-13,25H,6,14H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","","","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","Not in list","C22H28N2O3","Cc1cc(cc(CO)c1)C(=O)N(NC(=O)c2ccc(CC)cc2)C(C)(C)C","InChI=1/C22H28N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-13,25H,6,14H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","","","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","Not in list","C22H28N2O3","Cc1cc(cc(CO)c1)C(=O)N(NC(=O)c2ccc(CC)cc2)C(C)(C)C","InChI=1/C22H28N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-13,25H,6,14H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","","","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","Not in list","C22H28N2O3","Cc1cc(cc(CO)c1)C(=O)N(NC(=O)c2ccc(CC)cc2)C(C)(C)C","InChI=1/C22H28N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-13,25H,6,14H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","","","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","Not in list","C22H28N2O3","Cc1cc(cc(CO)c1)C(=O)N(NC(=O)c2ccc(CC)cc2)C(C)(C)C","InChI=1/C22H28N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-13,25H,6,14H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","","","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","Not in list","C22H28N2O3","Cc1cc(cc(CO)c1)C(=O)N(NC(=O)c2ccc(CC)cc2)C(C)(C)C","InChI=1/C22H28N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-13,25H,6,14H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","","","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","Not in list","C22H28N2O3","Cc1cc(cc(CO)c1)C(=O)N(NC(=O)c2ccc(CC)cc2)C(C)(C)C","InChI=1/C22H28N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-13,25H,6,14H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","","","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","Not in list","C22H28N2O3","Cc1cc(cc(CO)c1)C(=O)N(NC(=O)c2ccc(CC)cc2)C(C)(C)C","InChI=1/C22H28N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-13,25H,6,14H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","","","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","Not in list","C22H28N2O3","Cc1cc(cc(CO)c1)C(=O)N(NC(=O)c2ccc(CC)cc2)C(C)(C)C","InChI=1/C22H28N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-13,25H,6,14H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3-(hydroxymethyl)-5-methylbenzohydrazide conjugates","","","","Not in list","","","","organic","no structure","","","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3-(hydroxymethyl)-5-methylbenzohydrazide conjugates","","","","Not in list","","","","organic","no structure","","","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A pKM 101","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3-(hydroxymethyl)-5-methylbenzohydrazide conjugates","","","","Not in list","","","","organic","no structure","","","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A pKM 101","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3-(hydroxymethyl)-5-methylbenzohydrazide conjugates","","","","Not in list","","","","organic","no structure","","","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3-(hydroxymethyl)-5-methylbenzohydrazide conjugates","","","","Not in list","","","","organic","no structure","","","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3-(hydroxymethyl)-5-methylbenzohydrazide conjugates","","","","Not in list","","","","organic","no structure","","","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3-(hydroxymethyl)-5-methylbenzohydrazide conjugates","","","","Not in list","","","","organic","no structure","","","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3-(hydroxymethyl)-5-methylbenzohydrazide conjugates","","","","Not in list","","","","organic","no structure","","","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3-(hydroxymethyl)-5-methylbenzohydrazide conjugates","","","","Not in list","","","","organic","no structure","","","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3-(hydroxymethyl)-5-methylbenzohydrazide conjugates","","","","Not in list","","","","organic","no structure","","","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","","","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","Not in list","C22H28N2O3","Cc1cc(cc(CO)c1)C(=O)N(NC(=O)c2ccc(CC)cc2)C(C)(C)C","InChI=1/C22H28N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-13,25H,6,14H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","","","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","Not in list","C22H28N2O3","Cc1cc(cc(CO)c1)C(=O)N(NC(=O)c2ccc(CC)cc2)C(C)(C)C","InChI=1/C22H28N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-13,25H,6,14H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","","","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","Not in list","C22H28N2O3","Cc1cc(cc(CO)c1)C(=O)N(NC(=O)c2ccc(CC)cc2)C(C)(C)C","InChI=1/C22H28N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-13,25H,6,14H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","","","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","Not in list","C22H28N2O3","Cc1cc(cc(CO)c1)C(=O)N(NC(=O)c2ccc(CC)cc2)C(C)(C)C","InChI=1/C22H28N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-13,25H,6,14H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","","","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","Not in list","C22H28N2O3","Cc1cc(cc(CO)c1)C(=O)N(NC(=O)c2ccc(CC)cc2)C(C)(C)C","InChI=1/C22H28N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-13,25H,6,14H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","","","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","Not in list","C22H28N2O3","Cc1cc(cc(CO)c1)C(=O)N(NC(=O)c2ccc(CC)cc2)C(C)(C)C","InChI=1/C22H28N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-13,25H,6,14H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","","","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","Not in list","C22H28N2O3","Cc1cc(cc(CO)c1)C(=O)N(NC(=O)c2ccc(CC)cc2)C(C)(C)C","InChI=1/C22H28N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-13,25H,6,14H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","","","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","Not in list","C22H28N2O3","Cc1cc(cc(CO)c1)C(=O)N(NC(=O)c2ccc(CC)cc2)C(C)(C)C","InChI=1/C22H28N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-13,25H,6,14H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","","","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","Not in list","C22H28N2O3","Cc1cc(cc(CO)c1)C(=O)N(NC(=O)c2ccc(CC)cc2)C(C)(C)C","InChI=1/C22H28N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-13,25H,6,14H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","","","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","Not in list","C22H28N2O3","Cc1cc(cc(CO)c1)C(=O)N(NC(=O)c2ccc(CC)cc2)C(C)(C)C","InChI=1/C22H28N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-13,25H,6,14H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3-(hydroxymethyl)-5-methylbenzohydrazide conjugates","","","","Not in list","","","","organic","no structure","","","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3-(hydroxymethyl)-5-methylbenzohydrazide conjugates","","","","Not in list","","","","organic","no structure","","","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A pKM 101","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3-(hydroxymethyl)-5-methylbenzohydrazide conjugates","","","","Not in list","","","","organic","no structure","","","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A pKM 101","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3-(hydroxymethyl)-5-methylbenzohydrazide conjugates","","","","Not in list","","","","organic","no structure","","","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3-(hydroxymethyl)-5-methylbenzohydrazide conjugates","","","","Not in list","","","","organic","no structure","","","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3-(hydroxymethyl)-5-methylbenzohydrazide conjugates","","","","Not in list","","","","organic","no structure","","","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3-(hydroxymethyl)-5-methylbenzohydrazide conjugates","","","","Not in list","","","","organic","no structure","","","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3-(hydroxymethyl)-5-methylbenzohydrazide conjugates","","","","Not in list","","","","organic","no structure","","","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3-(hydroxymethyl)-5-methylbenzohydrazide conjugates","","","","Not in list","","","","organic","no structure","","","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3-(hydroxymethyl)-5-methylbenzohydrazide conjugates","","","","Not in list","","","","organic","no structure","","","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" "Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","5-({2-[(4-acetylphenyl)carbonyl]-1-tert-butylhydrazinyl}carbonyl)benzene-1,3-dicarboxylic acid","","","5-({2-[(4-acetylphenyl)carbonyl]-1-tert-butylhydrazinyl}carbonyl)benzene-1,3-dicarboxylic acid","Not in list","C22H22N2O7","O=C(O)c1cc(cc(c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C)C(O)=O","InChI=1/C22H22N2O7/c1-12(25)13-5-7-14(8-6-13)18(26)23-24(22(2,3)4)19(27)15-9-16(20(28)29)11-17(10-15)21(30)31/h5-11H,1-4H3,(H,23,26)(H,28,29)(H,30,31)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A pKM 101","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" "Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","5-({2-[(4-acetylphenyl)carbonyl]-1-tert-butylhydrazinyl}carbonyl)benzene-1,3-dicarboxylic acid","","","5-({2-[(4-acetylphenyl)carbonyl]-1-tert-butylhydrazinyl}carbonyl)benzene-1,3-dicarboxylic acid","Not in list","C22H22N2O7","O=C(O)c1cc(cc(c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C)C(O)=O","InChI=1/C22H22N2O7/c1-12(25)13-5-7-14(8-6-13)18(26)23-24(22(2,3)4)19(27)15-9-16(20(28)29)11-17(10-15)21(30)31/h5-11H,1-4H3,(H,23,26)(H,28,29)(H,30,31)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" "Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","5-({2-[(4-acetylphenyl)carbonyl]-1-tert-butylhydrazinyl}carbonyl)benzene-1,3-dicarboxylic acid","","","5-({2-[(4-acetylphenyl)carbonyl]-1-tert-butylhydrazinyl}carbonyl)benzene-1,3-dicarboxylic acid","Not in list","C22H22N2O7","O=C(O)c1cc(cc(c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C)C(O)=O","InChI=1/C22H22N2O7/c1-12(25)13-5-7-14(8-6-13)18(26)23-24(22(2,3)4)19(27)15-9-16(20(28)29)11-17(10-15)21(30)31/h5-11H,1-4H3,(H,23,26)(H,28,29)(H,30,31)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" @@ -17278,26 +17278,26 @@ ethyl carbonate","Not in list","C21H27NO5","CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3 "Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","[4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)phenyl]acetic acid","","","[4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)phenyl]acetic acid","Not in list","C22H26N2O4","O=C(O)Cc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C","InChI=1/C22H26N2O4/c1-14-10-15(2)12-18(11-14)21(28)24(22(3,4)5)23-20(27)17-8-6-16(7-9-17)13-19(25)26/h6-12H,13H2,1-5H3,(H,23,27)(H,25,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" "Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","[4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)phenyl]acetic acid","","","[4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)phenyl]acetic acid","Not in list","C22H26N2O4","O=C(O)Cc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C","InChI=1/C22H26N2O4/c1-14-10-15(2)12-18(11-14)21(28)24(22(3,4)5)23-20(27)17-8-6-16(7-9-17)13-19(25)26/h6-12H,13H2,1-5H3,(H,23,27)(H,25,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" "Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","[4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)phenyl]acetic acid","","","[4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)phenyl]acetic acid","Not in list","C22H26N2O4","O=C(O)Cc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C","InChI=1/C22H26N2O4/c1-14-10-15(2)12-18(11-14)21(28)24(22(3,4)5)23-20(27)17-8-6-16(7-9-17)13-19(25)26/h6-12H,13H2,1-5H3,(H,23,27)(H,25,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","","","N-tert-butyl-N?-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","Not in list","C22H28N2O3","OC(C)c1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C","InChI=1/C22H28N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13,16,25H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","","","N-tert-butyl-N?-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","Not in list","C22H28N2O3","OC(C)c1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C","InChI=1/C22H28N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13,16,25H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","","","N-tert-butyl-N?-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","Not in list","C22H28N2O3","OC(C)c1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C","InChI=1/C22H28N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13,16,25H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","","","N-tert-butyl-N?-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","Not in list","C22H28N2O3","OC(C)c1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C","InChI=1/C22H28N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13,16,25H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","","","N-tert-butyl-N?-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","Not in list","C22H28N2O3","OC(C)c1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C","InChI=1/C22H28N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13,16,25H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","","","N-tert-butyl-N?-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","Not in list","C22H28N2O3","OC(C)c1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C","InChI=1/C22H28N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13,16,25H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","","","N-tert-butyl-N?-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","Not in list","C22H28N2O3","OC(C)c1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C","InChI=1/C22H28N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13,16,25H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","","","N-tert-butyl-N?-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","Not in list","C22H28N2O3","OC(C)c1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C","InChI=1/C22H28N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13,16,25H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","","","N-tert-butyl-N?-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","Not in list","C22H28N2O3","OC(C)c1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C","InChI=1/C22H28N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13,16,25H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","","","N-tert-butyl-N?-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","Not in list","C22H28N2O3","OC(C)c1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C","InChI=1/C22H28N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13,16,25H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","","","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","Not in list","C22H26N2O3","CCc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C=O)c2)C(C)(C)C","InChI=1/C22H26N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-14H,6H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","","","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","Not in list","C22H26N2O3","CCc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C=O)c2)C(C)(C)C","InChI=1/C22H26N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-14H,6H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","","","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","Not in list","C22H26N2O3","CCc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C=O)c2)C(C)(C)C","InChI=1/C22H26N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-14H,6H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","","","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","Not in list","C22H26N2O3","CCc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C=O)c2)C(C)(C)C","InChI=1/C22H26N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-14H,6H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","","","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","Not in list","C22H26N2O3","CCc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C=O)c2)C(C)(C)C","InChI=1/C22H26N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-14H,6H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","","","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","Not in list","C22H26N2O3","CCc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C=O)c2)C(C)(C)C","InChI=1/C22H26N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-14H,6H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","","","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","Not in list","C22H26N2O3","CCc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C=O)c2)C(C)(C)C","InChI=1/C22H26N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-14H,6H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","","","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","Not in list","C22H26N2O3","CCc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C=O)c2)C(C)(C)C","InChI=1/C22H26N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-14H,6H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","","","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","Not in list","C22H26N2O3","CCc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C=O)c2)C(C)(C)C","InChI=1/C22H26N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-14H,6H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","","","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","Not in list","C22H26N2O3","CCc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C=O)c2)C(C)(C)C","InChI=1/C22H26N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-14H,6H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","","","N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","Not in list","C22H28N2O3","OC(C)c1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C","InChI=1/C22H28N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13,16,25H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","","","N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","Not in list","C22H28N2O3","OC(C)c1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C","InChI=1/C22H28N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13,16,25H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","","","N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","Not in list","C22H28N2O3","OC(C)c1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C","InChI=1/C22H28N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13,16,25H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","","","N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","Not in list","C22H28N2O3","OC(C)c1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C","InChI=1/C22H28N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13,16,25H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","","","N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","Not in list","C22H28N2O3","OC(C)c1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C","InChI=1/C22H28N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13,16,25H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","","","N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","Not in list","C22H28N2O3","OC(C)c1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C","InChI=1/C22H28N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13,16,25H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","","","N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","Not in list","C22H28N2O3","OC(C)c1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C","InChI=1/C22H28N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13,16,25H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","","","N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","Not in list","C22H28N2O3","OC(C)c1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C","InChI=1/C22H28N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13,16,25H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","","","N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","Not in list","C22H28N2O3","OC(C)c1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C","InChI=1/C22H28N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13,16,25H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","","","N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","Not in list","C22H28N2O3","OC(C)c1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C","InChI=1/C22H28N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13,16,25H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","","","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","Not in list","C22H26N2O3","CCc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C=O)c2)C(C)(C)C","InChI=1/C22H26N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-14H,6H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","","","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","Not in list","C22H26N2O3","CCc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C=O)c2)C(C)(C)C","InChI=1/C22H26N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-14H,6H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","","","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","Not in list","C22H26N2O3","CCc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C=O)c2)C(C)(C)C","InChI=1/C22H26N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-14H,6H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","","","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","Not in list","C22H26N2O3","CCc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C=O)c2)C(C)(C)C","InChI=1/C22H26N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-14H,6H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","","","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","Not in list","C22H26N2O3","CCc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C=O)c2)C(C)(C)C","InChI=1/C22H26N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-14H,6H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","","","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","Not in list","C22H26N2O3","CCc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C=O)c2)C(C)(C)C","InChI=1/C22H26N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-14H,6H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","","","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","Not in list","C22H26N2O3","CCc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C=O)c2)C(C)(C)C","InChI=1/C22H26N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-14H,6H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","","","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","Not in list","C22H26N2O3","CCc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C=O)c2)C(C)(C)C","InChI=1/C22H26N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-14H,6H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","","","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","Not in list","C22H26N2O3","CCc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C=O)c2)C(C)(C)C","InChI=1/C22H26N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-14H,6H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","","","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","Not in list","C22H26N2O3","CCc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C=O)c2)C(C)(C)C","InChI=1/C22H26N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-14H,6H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" "Tefluthrin","","79538-32-2","single chemical entity","Component is identical to the substance","Tefluthrin","","79538-32-2","2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate","Tefluthrin","C17H14ClF7O2","O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F","InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tefluthrin","2006","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin","40521","2010","doi:10.2903/j.efsa.2010.1709" "Tefluthrin","","79538-32-2","single chemical entity","Component is identical to the substance","Tefluthrin","","79538-32-2","2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate","Tefluthrin","C17H14ClF7O2","O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F","InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tefluthrin","2006","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin","40521","2010","doi:10.2903/j.efsa.2010.1709" "Tefluthrin","","79538-32-2","single chemical entity","Component is identical to the substance","Tefluthrin","","79538-32-2","2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate","Tefluthrin","C17H14ClF7O2","O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F","InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tefluthrin","2006","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin","40521","2010","doi:10.2903/j.efsa.2010.1709" @@ -18376,7 +18376,7 @@ sulfanylcarbamoyl]oxyethanimidothioate","Thiodicarb","C10H18N4O4S3","CC(=NOC(=O) "Thifensulfuron-methyl","616-673-4","79277-27-3","single chemical entity","Component is a metabolite of the substance","methyl 3-sulfamoylthiophene-2-carboxylate","","","methyl 3-sulfamoylthiophene-2-carboxylate","Not in list","C6H7NO4S2","O=S(N)(=O)c1ccsc1C(=O)OC","InChI=1/C6H7NO4S2/c1-11-6(8)5-4(2-3-12-5)13(7,9)10/h2-3H,1H3,(H2,7,9,10)","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","Swiss","10","Male/Female","oral: gavage","48","h","yes","not applicable","Negative","","no evidence","RMS: The United Kingdom","Thifensulfuron-methyl","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl","42208","2015","doi:10.2903/j.efsa.2015.4201" "Thifensulfuron-methyl","616-673-4","79277-27-3","single chemical entity","Component is a metabolite of the substance","methyl 3-sulfamoylthiophene-2-carboxylate","","","methyl 3-sulfamoylthiophene-2-carboxylate","Not in list","C6H7NO4S2","O=S(N)(=O)c1ccsc1C(=O)OC","InChI=1/C6H7NO4S2/c1-11-6(8)5-4(2-3-12-5)13(7,9)10/h2-3H,1H3,(H2,7,9,10)","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","Swiss","10","Male/Female","oral: gavage","72","h","yes","not applicable","Negative","","no evidence","RMS: The United Kingdom","Thifensulfuron-methyl","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl","42208","2015","doi:10.2903/j.efsa.2015.4201" "Name","Type","Description","isNullable","isRecordUniqueIdentifier","Catalogue Code","Last update" -"GUIDELINE_QUALIFIER","Character","Indicates how strict the guideline given in the subsequent field ?Guideline? was followed or whether no guideline was used or available/required",,"FALSE",,"26/10/2015" +"GUIDELINE_QUALIFIER","Character","Indicates how strict the guideline given in the subsequent field 'Guideline' was followed or whether no guideline was used or available/required",,"FALSE",,"26/10/2015" "GENOTOXGUIDELINEFULLTXT","Character","Full description for the guideline followed",,"FALSE",,"10-27-19" "DEVIATION","Character","Indicates whether a genotoxicity study contains deviations from the standard test protocol",,"FALSE",,"26/10/2015" "GLP_COMPL","Character","Indicates whether a GLP certificate or compliance statement is available",,"FALSE",,"26/10/2015" diff --git a/data/GENOTOX_data_and_dictionary.tsv b/data/GENOTOX_data_and_dictionary.tsv new file mode 100644 index 0000000..d86bb88 --- /dev/null +++ b/data/GENOTOX_data_and_dictionary.tsv @@ -0,0 +1,17928 @@ +SUB_NAME SUB_ECSUBINVENTENTRYREF SUB_CASNUMBER SUB_TYPE QUALIFIER COM_NAME COM_ECSUBINVENTENTRYREF COM_CASNUMBER IUPACNAME COMPARAMNAME MOLECULARFORMULA SMILESNOTATION INCHI COM_TYPE COM_STRUCTURESHOWN SMILESNOTATIONSOURCE INCHI_NOTATIONSOURCE GENOTOX_ENDPOINT TESTTYPE METHOD_TYPE GUIDELINE_QUALIFIER GENOTOXGUIDELINEFULLTXT DEVIATION ACCEPTABILITY SPECIES STRAIN NUMBER_INDIVIDUALS SEX ROUTE EXP_PERIOD EXPPERIODUNIT CONTROL MET_INDICATOR RESULTS MOUSELYMPHTEST INVIVOTISSUEEXP DARAuthor DARTitle DARYear OpinionType OpinionAuthor OpinionTitle PUBLICATIONDATE OpinionPubYear DOI
+1,4-Dimethylnaphthalene 209-335-9 571-58-4 single chemical entity Component is identical to the substance 1,4-Dimethylnaphthalene 209-335-9 571-58-4 1,4-dimethylnaphthalene Not in list C12H12 Cc1ccc(C)c2ccccc12 InChI=1/C12H12/c1-9-7-8-10(2)12-6-4-3-5-11(9)12/h3-8H,1-2H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 48.0000000000 h yes not applicable Negative direct evidence-cytotoxicity$indirect evidence-systemic toxicity RMS: The Netherlands 1,4-Dimethylnaphthalene (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1,4-dimethylnaphthalene. 18Oct2013 2013 doi:10.2903/j.efsa.2013.3229
+1,4-Dimethylnaphthalene 209-335-9 571-58-4 single chemical entity Component is identical to the substance 1,4-Dimethylnaphthalene 209-335-9 571-58-4 1,4-dimethylnaphthalene Not in list C12H12 Cc1ccc(C)c2ccccc12 InChI=1/C12H12/c1-9-7-8-10(2)12-6-4-3-5-11(9)12/h3-8H,1-2H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 72.0000000000 h yes not applicable Negative direct evidence-cytotoxicity$indirect evidence-systemic toxicity RMS: The Netherlands 1,4-Dimethylnaphthalene (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1,4-dimethylnaphthalene. 18Oct2013 2013 doi:10.2903/j.efsa.2013.3229
+1,4-Dimethylnaphthalene 209-335-9 571-58-4 single chemical entity Component is identical to the substance 1,4-Dimethylnaphthalene 209-335-9 571-58-4 1,4-dimethylnaphthalene Not in list C12H12 Cc1ccc(C)c2ccccc12 InChI=1/C12H12/c1-9-7-8-10(2)12-6-4-3-5-11(9)12/h3-8H,1-2H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes not applicable Negative direct evidence-cytotoxicity$indirect evidence-systemic toxicity RMS: The Netherlands 1,4-Dimethylnaphthalene (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1,4-dimethylnaphthalene. 18Oct2013 2013 doi:10.2903/j.efsa.2013.3229
+1,4-Dimethylnaphthalene 209-335-9 571-58-4 single chemical entity Component is identical to the substance 1,4-Dimethylnaphthalene 209-335-9 571-58-4 1,4-dimethylnaphthalene Not in list C12H12 Cc1ccc(C)c2ccccc12 InChI=1/C12H12/c1-9-7-8-10(2)12-6-4-3-5-11(9)12/h3-8H,1-2H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 72.0000000000 h yes not applicable Negative direct evidence-cytotoxicity$indirect evidence-systemic toxicity RMS: The Netherlands 1,4-Dimethylnaphthalene (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1,4-dimethylnaphthalene. 18Oct2013 2013 doi:10.2903/j.efsa.2013.3229
+1,4-Dimethylnaphthalene 209-335-9 571-58-4 single chemical entity Component is identical to the substance 1,4-Dimethylnaphthalene 209-335-9 571-58-4 1,4-dimethylnaphthalene Not in list C12H12 Cc1ccc(C)c2ccccc12 InChI=1/C12H12/c1-9-7-8-10(2)12-6-4-3-5-11(9)12/h3-8H,1-2H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 48.0000000000 h yes not applicable Negative direct evidence-cytotoxicity$indirect evidence-systemic toxicity RMS: The Netherlands 1,4-Dimethylnaphthalene (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1,4-dimethylnaphthalene. 18Oct2013 2013 doi:10.2903/j.efsa.2013.3229
+1,4-Dimethylnaphthalene 209-335-9 571-58-4 single chemical entity Component is identical to the substance 1,4-Dimethylnaphthalene 209-335-9 571-58-4 1,4-dimethylnaphthalene Not in list C12H12 Cc1ccc(C)c2ccccc12 InChI=1/C12H12/c1-9-7-8-10(2)12-6-4-3-5-11(9)12/h3-8H,1-2H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes not applicable Negative direct evidence-cytotoxicity$indirect evidence-systemic toxicity RMS: The Netherlands 1,4-Dimethylnaphthalene (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1,4-dimethylnaphthalene. 18Oct2013 2013 doi:10.2903/j.efsa.2013.3229
+1,4-Dimethylnaphthalene 209-335-9 571-58-4 single chemical entity Component is identical to the substance 1,4-Dimethylnaphthalene 209-335-9 571-58-4 1,4-dimethylnaphthalene Not in list C12H12 Cc1ccc(C)c2ccccc12 InChI=1/C12H12/c1-9-7-8-10(2)12-6-4-3-5-11(9)12/h3-8H,1-2H3 organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo Equivalent or similar to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) Yes Acceptable Rat (as animal) Sprague-Dawley 4 Male oral: gavage 4.0000000000 h yes not applicable Negative RMS: The Netherlands 1,4-Dimethylnaphthalene (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1,4-dimethylnaphthalene. 18Oct2013 2013 doi:10.2903/j.efsa.2013.3229
+1,4-Dimethylnaphthalene 209-335-9 571-58-4 single chemical entity Component is identical to the substance 1,4-Dimethylnaphthalene 209-335-9 571-58-4 1,4-dimethylnaphthalene Not in list C12H12 Cc1ccc(C)c2ccccc12 InChI=1/C12H12/c1-9-7-8-10(2)12-6-4-3-5-11(9)12/h3-8H,1-2H3 organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo Equivalent or similar to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) Yes Acceptable Rat (as animal) Sprague-Dawley 4 Male oral: gavage 14.0000000000 h yes not applicable Negative RMS: The Netherlands 1,4-Dimethylnaphthalene (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1,4-dimethylnaphthalene. 18Oct2013 2013 doi:10.2903/j.efsa.2013.3229
+1-Methylcyclopropene 3100-04-7 single chemical entity Component is identical to the substance 1-Methylcyclopropene 3100-04-7 1-methylcyclopropene 1-methylcyclopropene C4H6 CC1=CC1 InChI=1S/C4H6/c1-4-2-3-4/h2H,3H2,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes without Negative RMS: The United Kingdom 1-Methylcyclopropene 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance 1-methylcyclopropene 12May2005 2005 doi:10.2903/j.efsa.2005.30r
+1-Methylcyclopropene 3100-04-7 single chemical entity Component is identical to the substance 1-Methylcyclopropene 3100-04-7 1-methylcyclopropene 1-methylcyclopropene C4H6 CC1=CC1 InChI=1S/C4H6/c1-4-2-3-4/h2H,3H2,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes with Negative RMS: The United Kingdom 1-Methylcyclopropene 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance 1-methylcyclopropene 12May2005 2005 doi:10.2903/j.efsa.2005.30r
+1-Methylcyclopropene 3100-04-7 single chemical entity Component is identical to the substance 1-Methylcyclopropene 3100-04-7 1-methylcyclopropene 1-methylcyclopropene C4H6 CC1=CC1 InChI=1S/C4H6/c1-4-2-3-4/h2H,3H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: The United Kingdom 1-Methylcyclopropene 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance 1-methylcyclopropene 12May2005 2005 doi:10.2903/j.efsa.2005.30r
+1-Methylcyclopropene 3100-04-7 single chemical entity Component is identical to the substance 1-Methylcyclopropene 3100-04-7 1-methylcyclopropene 1-methylcyclopropene C4H6 CC1=CC1 InChI=1S/C4H6/c1-4-2-3-4/h2H,3H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: The United Kingdom 1-Methylcyclopropene 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance 1-methylcyclopropene 12May2005 2005 doi:10.2903/j.efsa.2005.30r
+1-Methylcyclopropene 3100-04-7 single chemical entity Component is identical to the substance 1-Methylcyclopropene 3100-04-7 1-methylcyclopropene 1-methylcyclopropene C4H6 CC1=CC1 InChI=1S/C4H6/c1-4-2-3-4/h2H,3H2,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female intraperitoneal 48.0000000000 h yes not applicable Negative no evidence RMS: The United Kingdom 1-Methylcyclopropene 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance 1-methylcyclopropene 12May2005 2005 doi:10.2903/j.efsa.2005.30r
+1-Methylcyclopropene 3100-04-7 single chemical entity Component is identical to the substance 1-Methylcyclopropene 3100-04-7 1-methylcyclopropene 1-methylcyclopropene C4H6 CC1=CC1 InChI=1S/C4H6/c1-4-2-3-4/h2H,3H2,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female intraperitoneal 24.0000000000 h yes not applicable Negative no evidence RMS: The United Kingdom 1-Methylcyclopropene 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance 1-methylcyclopropene 12May2005 2005 doi:10.2903/j.efsa.2005.30r
+2-(1-Naphthyl)acetamide 201-704-2 86-86-2 single chemical entity Component is identical to the substance 2-(1-Naphthyl)acetamide 201-704-2 86-86-2 2-naphthalen-1-ylacetamide Not in list C12H11NO NC(=O)Cc1cccc2ccccc12 InChI=1/C12H11NO/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H2,13,14) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: France Naphthaleneacetamide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2-(1-naphthyl)acetamide (notified as 1-naphthylacetamide) 23Feb2011 2011 doi:10.2903/j.efsa.2011.2020
+2-(1-Naphthyl)acetamide 201-704-2 86-86-2 single chemical entity Component is identical to the substance 2-(1-Naphthyl)acetamide 201-704-2 86-86-2 2-naphthalen-1-ylacetamide Not in list C12H11NO NC(=O)Cc1cccc2ccccc12 InChI=1/C12H11NO/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H2,13,14) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: France Naphthaleneacetamide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2-(1-naphthyl)acetamide (notified as 1-naphthylacetamide) 23Feb2011 2011 doi:10.2903/j.efsa.2011.2020
+2-(1-Naphthyl)acetamide 201-704-2 86-86-2 single chemical entity Component is identical to the substance 2-(1-Naphthyl)acetamide 201-704-2 86-86-2 2-naphthalen-1-ylacetamide Not in list C12H11NO NC(=O)Cc1cccc2ccccc12 InChI=1/C12H11NO/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H2,13,14) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Positive small colonies RMS: France Naphthaleneacetamide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2-(1-naphthyl)acetamide (notified as 1-naphthylacetamide) 23Feb2011 2011 doi:10.2903/j.efsa.2011.2020
+2-(1-Naphthyl)acetamide 201-704-2 86-86-2 single chemical entity Component is identical to the substance 2-(1-Naphthyl)acetamide 201-704-2 86-86-2 2-naphthalen-1-ylacetamide Not in list C12H11NO NC(=O)Cc1cccc2ccccc12 InChI=1/C12H11NO/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H2,13,14) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative no information RMS: France Naphthaleneacetamide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2-(1-naphthyl)acetamide (notified as 1-naphthylacetamide) 23Feb2011 2011 doi:10.2903/j.efsa.2011.2020
+2-(1-Naphthyl)acetamide 201-704-2 86-86-2 single chemical entity Component is identical to the substance 2-(1-Naphthyl)acetamide 201-704-2 86-86-2 2-naphthalen-1-ylacetamide Not in list C12H11NO NC(=O)Cc1cccc2ccccc12 InChI=1/C12H11NO/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H2,13,14) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: France Naphthaleneacetamide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2-(1-naphthyl)acetamide (notified as 1-naphthylacetamide) 23Feb2011 2011 doi:10.2903/j.efsa.2011.2020
+2-(1-Naphthyl)acetamide 201-704-2 86-86-2 single chemical entity Component is identical to the substance 2-(1-Naphthyl)acetamide 201-704-2 86-86-2 2-naphthalen-1-ylacetamide Not in list C12H11NO NC(=O)Cc1cccc2ccccc12 InChI=1/C12H11NO/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H2,13,14) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: France Naphthaleneacetamide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2-(1-naphthyl)acetamide (notified as 1-naphthylacetamide) 23Feb2011 2011 doi:10.2903/j.efsa.2011.2020
+2-(1-Naphthyl)acetamide 201-704-2 86-86-2 single chemical entity Component is identical to the substance 2-(1-Naphthyl)acetamide 201-704-2 86-86-2 2-naphthalen-1-ylacetamide Not in list C12H11NO NC(=O)Cc1cccc2ccccc12 InChI=1/C12H11NO/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H2,13,14) organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: France Naphthaleneacetamide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2-(1-naphthyl)acetamide (notified as 1-naphthylacetamide) 23Feb2011 2011 doi:10.2903/j.efsa.2011.2020
+2-(1-Naphthyl)acetamide 201-704-2 86-86-2 single chemical entity Component is identical to the substance 2-(1-Naphthyl)acetamide 201-704-2 86-86-2 2-naphthalen-1-ylacetamide Not in list C12H11NO NC(=O)Cc1cccc2ccccc12 InChI=1/C12H11NO/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H2,13,14) organic compound Other Other genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro According to OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay) No Acceptable Saccharomyces cerevisiae (as organism) D6 Not reported no data with Negative RMS: France Naphthaleneacetamide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2-(1-naphthyl)acetamide (notified as 1-naphthylacetamide) 23Feb2011 2011 doi:10.2903/j.efsa.2011.2020
+2-(1-Naphthyl)acetamide 201-704-2 86-86-2 single chemical entity Component is identical to the substance 2-(1-Naphthyl)acetamide 201-704-2 86-86-2 2-naphthalen-1-ylacetamide Not in list C12H11NO NC(=O)Cc1cccc2ccccc12 InChI=1/C12H11NO/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H2,13,14) organic compound Other Other genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro Equivalent or similar to OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay) Yes Acceptable Saccharomyces cerevisiae (as organism) D6 Not reported no data without Negative RMS: France Naphthaleneacetamide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2-(1-naphthyl)acetamide (notified as 1-naphthylacetamide) 23Feb2011 2011 doi:10.2903/j.efsa.2011.2020
+2-(1-Naphthyl)acetamide 201-704-2 86-86-2 single chemical entity Component is identical to the substance 2-(1-Naphthyl)acetamide 201-704-2 86-86-2 2-naphthalen-1-ylacetamide Not in list C12H11NO NC(=O)Cc1cccc2ccccc12 InChI=1/C12H11NO/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H2,13,14) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity RMS: France Naphthaleneacetamide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2-(1-naphthyl)acetamide (notified as 1-naphthylacetamide) 23Feb2011 2011 doi:10.2903/j.efsa.2011.2020
+2-(1-Naphthyl)acetamide 201-704-2 86-86-2 single chemical entity Component is identical to the substance 2-(1-Naphthyl)acetamide 201-704-2 86-86-2 2-naphthalen-1-ylacetamide Not in list C12H11NO NC(=O)Cc1cccc2ccccc12 InChI=1/C12H11NO/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H2,13,14) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 72.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity RMS: France Naphthaleneacetamide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2-(1-naphthyl)acetamide (notified as 1-naphthylacetamide) 23Feb2011 2011 doi:10.2903/j.efsa.2011.2020
+2-(1-Naphthyl)acetamide 201-704-2 86-86-2 single chemical entity Component is identical to the substance 2-(1-Naphthyl)acetamide 201-704-2 86-86-2 2-naphthalen-1-ylacetamide Not in list C12H11NO NC(=O)Cc1cccc2ccccc12 InChI=1/C12H11NO/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H2,13,14) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity RMS: France Naphthaleneacetamide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2-(1-naphthyl)acetamide (notified as 1-naphthylacetamide) 23Feb2011 2011 doi:10.2903/j.efsa.2011.2020
+2-(1-Naphthyl)acetamide 201-704-2 86-86-2 single chemical entity Component is identical to the substance 2-(1-Naphthyl)acetamide 201-704-2 86-86-2 2-naphthalen-1-ylacetamide Not in list C12H11NO NC(=O)Cc1cccc2ccccc12 InChI=1/C12H11NO/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H2,13,14) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) ICR 10 Male/Female intraperitoneal 24.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity$indirect evidence-systemic toxicity RMS: France Naphthaleneacetamide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2-(1-naphthyl)acetamide (notified as 1-naphthylacetamide) 23Feb2011 2011 doi:10.2903/j.efsa.2011.2020
+2-(1-Naphthyl)acetamide 201-704-2 86-86-2 single chemical entity Component is identical to the substance 2-(1-Naphthyl)acetamide 201-704-2 86-86-2 2-naphthalen-1-ylacetamide Not in list C12H11NO NC(=O)Cc1cccc2ccccc12 InChI=1/C12H11NO/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H2,13,14) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) ICR 10 Male/Female intraperitoneal 48.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity$indirect evidence-systemic toxicity RMS: France Naphthaleneacetamide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2-(1-naphthyl)acetamide (notified as 1-naphthylacetamide) 23Feb2011 2011 doi:10.2903/j.efsa.2011.2020
+2-(1-Naphthyl)acetamide 201-704-2 86-86-2 single chemical entity Component is identical to the substance 2-(1-Naphthyl)acetamide 201-704-2 86-86-2 2-naphthalen-1-ylacetamide Not in list C12H11NO NC(=O)Cc1cccc2ccccc12 InChI=1/C12H11NO/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H2,13,14) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) ICR 10 Male/Female intraperitoneal 72.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity$indirect evidence-systemic toxicity RMS: France Naphthaleneacetamide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2-(1-naphthyl)acetamide (notified as 1-naphthylacetamide) 23Feb2011 2011 doi:10.2903/j.efsa.2011.2020
+1-Naphthylacetic acid 201-705-8 86-87-3 single chemical entity Component is identical to the substance 1-Naphthylacetic acid 201-705-8 86-87-3 1-2-naphthalen-1-ylacetic acid 1-naphthylacetic acid C12H10O2 OC(=O)Cc1cccc2ccccc12 InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: France Naphtaleneacetic acid 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid 23Feb2011 2011 doi:10.2903/j.efsa.2011.2019
+1-Naphthylacetic acid 201-705-8 86-87-3 single chemical entity Component is identical to the substance 1-Naphthylacetic acid 201-705-8 86-87-3 1-2-naphthalen-1-ylacetic acid 1-naphthylacetic acid C12H10O2 OC(=O)Cc1cccc2ccccc12 InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: France Naphtaleneacetic acid 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid 23Feb2011 2011 doi:10.2903/j.efsa.2011.2019
+1-Naphthylacetic acid 201-705-8 86-87-3 single chemical entity Component is identical to the substance 1-Naphthylacetic acid 201-705-8 86-87-3 1-2-naphthalen-1-ylacetic acid 1-naphthylacetic acid C12H10O2 OC(=O)Cc1cccc2ccccc12 InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Ambiguous no information RMS: France Naphtaleneacetic acid 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid 23Feb2011 2011 doi:10.2903/j.efsa.2011.2019
+1-Naphthylacetic acid 201-705-8 86-87-3 single chemical entity Component is identical to the substance 1-Naphthylacetic acid 201-705-8 86-87-3 1-2-naphthalen-1-ylacetic acid 1-naphthylacetic acid C12H10O2 OC(=O)Cc1cccc2ccccc12 InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Ambiguous no information RMS: France Naphtaleneacetic acid 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid 23Feb2011 2011 doi:10.2903/j.efsa.2011.2019
+1-Naphthylacetic acid 201-705-8 86-87-3 single chemical entity Component is identical to the substance 1-Naphthylacetic acid 201-705-8 86-87-3 1-2-naphthalen-1-ylacetic acid 1-naphthylacetic acid C12H10O2 OC(=O)Cc1cccc2ccccc12 InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: France Naphtaleneacetic acid 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid 23Feb2011 2011 doi:10.2903/j.efsa.2011.2019
+1-Naphthylacetic acid 201-705-8 86-87-3 single chemical entity Component is a metabolite of the substance ethyl 1-naphthylacetate 2122-70-5 ethyl 2-naphthalen-1-ylacetate Not in list C14H14O2 CCOC(=O)CC1=CC=CC2=CC=CC=C21 InChI=1S/C14H14O2/c1-2-16-14(15)10-12-8-5-7-11-6-3-4-9-13(11)12/h3-9H,2,10H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: France Naphtaleneacetic acid 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid 23Feb2011 2011 doi:10.2903/j.efsa.2011.2019
+1-Naphthylacetic acid 201-705-8 86-87-3 single chemical entity Component is identical to the substance 1-Naphthylacetic acid 201-705-8 86-87-3 1-2-naphthalen-1-ylacetic acid 1-naphthylacetic acid C12H10O2 OC(=O)Cc1cccc2ccccc12 InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: France Naphtaleneacetic acid 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid 23Feb2011 2011 doi:10.2903/j.efsa.2011.2019
+1-Naphthylacetic acid 201-705-8 86-87-3 single chemical entity Component is identical to the substance 1-Naphthylacetic acid 201-705-8 86-87-3 1-2-naphthalen-1-ylacetic acid 1-naphthylacetic acid C12H10O2 OC(=O)Cc1cccc2ccccc12 InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: France Naphtaleneacetic acid 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid 23Feb2011 2011 doi:10.2903/j.efsa.2011.2019
+1-Naphthylacetic acid 201-705-8 86-87-3 single chemical entity Component is a metabolite of the substance sodium 1-naphthylacetate 61-31-4 sodium;2-naphthalen-1-ylacetate Not in list C12H9NaO2 C1=CC=C2C(=C1)C=CC=C2CC(=O)[O-].[Na+] InChI=1S/C12H10O2.Na/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10;/h1-7H,8H2,(H,13,14);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Positive RMS: France Naphtaleneacetic acid 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid 23Feb2011 2011 doi:10.2903/j.efsa.2011.2019
+1-Naphthylacetic acid 201-705-8 86-87-3 single chemical entity Component is a metabolite of the substance sodium 1-naphthylacetate 61-31-4 sodium;2-naphthalen-1-ylacetate Not in list C12H9NaO2 C1=CC=C2C(=C1)C=CC=C2CC(=O)[O-].[Na+] InChI=1S/C12H10O2.Na/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10;/h1-7H,8H2,(H,13,14);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: France Naphtaleneacetic acid 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid 23Feb2011 2011 doi:10.2903/j.efsa.2011.2019
+1-Naphthylacetic acid 201-705-8 86-87-3 single chemical entity Component is identical to the substance 1-Naphthylacetic acid 201-705-8 86-87-3 1-2-naphthalen-1-ylacetic acid 1-naphthylacetic acid C12H10O2 OC(=O)Cc1cccc2ccccc12 InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 6 Male/Female oral: unspecified 24.0000000000 h yes not applicable Negative direct evidence-cytotoxicity RMS: France Naphtaleneacetic acid 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid 23Feb2011 2011 doi:10.2903/j.efsa.2011.2019
+1-Naphthylacetic acid 201-705-8 86-87-3 single chemical entity Component is a metabolite of the substance sodium 1-naphthylacetate 61-31-4 sodium;2-naphthalen-1-ylacetate Not in list C12H9NaO2 C1=CC=C2C(=C1)C=CC=C2CC(=O)[O-].[Na+] InChI=1S/C12H10O2.Na/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10;/h1-7H,8H2,(H,13,14);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable Rat (as animal) Wistar 5 Male oral: unspecified 24.0000000000 h yes not applicable Negative no evidence RMS: France Naphtaleneacetic acid 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid 23Feb2011 2011 doi:10.2903/j.efsa.2011.2019
+1-Naphthylacetic acid 201-705-8 86-87-3 single chemical entity Component is a metabolite of the substance sodium 1-naphthylacetate 61-31-4 sodium;2-naphthalen-1-ylacetate Not in list C12H9NaO2 C1=CC=C2C(=C1)C=CC=C2CC(=O)[O-].[Na+] InChI=1S/C12H10O2.Na/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10;/h1-7H,8H2,(H,13,14);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo Equivalent or similar to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) Yes Acceptable Rat (as animal) Wistar 3 Male oral: gavage 16.0000000000 h yes, concurrent vehicle not applicable Negative RMS: France Naphtaleneacetic acid 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid 23Feb2011 2011 doi:10.2903/j.efsa.2011.2019
+1-Naphthylacetic acid 201-705-8 86-87-3 single chemical entity Component is a metabolite of the substance sodium 1-naphthylacetate 61-31-4 sodium;2-naphthalen-1-ylacetate Not in list C12H9NaO2 C1=CC=C2C(=C1)C=CC=C2CC(=O)[O-].[Na+] InChI=1S/C12H10O2.Na/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10;/h1-7H,8H2,(H,13,14);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo Equivalent or similar to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) Yes Acceptable Rat (as animal) Wistar 3 Male oral: gavage 2.0000000000 h yes, concurrent vehicle not applicable Negative RMS: France Naphtaleneacetic acid 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid 23Feb2011 2011 doi:10.2903/j.efsa.2011.2019
+1-Naphthylacetic acid 201-705-8 86-87-3 single chemical entity Component is identical to the substance 1-Naphthylacetic acid 201-705-8 86-87-3 1-2-naphthalen-1-ylacetic acid 1-naphthylacetic acid C12H10O2 OC(=O)Cc1cccc2ccccc12 InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14) organic compound Other Other chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) Yes Acceptable Rat (as animal) Sprague-Dawley 10 Male oral: gavage 5.0000000000 D yes not applicable Negative RMS: France Naphtaleneacetic acid 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid 23Feb2011 2011 doi:10.2903/j.efsa.2011.2019
+6-Benzyladenine 214-927-5 1214-39-7 single chemical entity Component is identical to the substance 6-Benzyladenine 214-927-5 1214-39-7 N-benzyl-7H-purin-6-amine 6-Benzyladenine C12H11N5 C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3 InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France 6-Benzyladenine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine 22Oct2010 2010 doi:10.2903/j.efsa.2010.1716
+6-Benzyladenine 214-927-5 1214-39-7 single chemical entity Component is identical to the substance 6-Benzyladenine 214-927-5 1214-39-7 N-benzyl-7H-purin-6-amine 6-Benzyladenine C12H11N5 C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3 InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: France 6-Benzyladenine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine 22Oct2010 2010 doi:10.2903/j.efsa.2010.1716
+6-Benzyladenine 214-927-5 1214-39-7 single chemical entity Component is identical to the substance 6-Benzyladenine 214-927-5 1214-39-7 N-benzyl-7H-purin-6-amine 6-Benzyladenine C12H11N5 C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3 InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France 6-Benzyladenine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine 22Oct2010 2010 doi:10.2903/j.efsa.2010.1716
+6-Benzyladenine 214-927-5 1214-39-7 single chemical entity Component is identical to the substance 6-Benzyladenine 214-927-5 1214-39-7 N-benzyl-7H-purin-6-amine 6-Benzyladenine C12H11N5 C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3 InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France 6-Benzyladenine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine 22Oct2010 2010 doi:10.2903/j.efsa.2010.1716
+6-Benzyladenine 214-927-5 1214-39-7 single chemical entity Component is identical to the substance 6-Benzyladenine 214-927-5 1214-39-7 N-benzyl-7H-purin-6-amine 6-Benzyladenine C12H11N5 C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3 InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France 6-Benzyladenine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine 22Oct2010 2010 doi:10.2903/j.efsa.2010.1716
+6-Benzyladenine 214-927-5 1214-39-7 single chemical entity Component is identical to the substance 6-Benzyladenine 214-927-5 1214-39-7 N-benzyl-7H-purin-6-amine 6-Benzyladenine C12H11N5 C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3 InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France 6-Benzyladenine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine 22Oct2010 2010 doi:10.2903/j.efsa.2010.1716
+6-Benzyladenine 214-927-5 1214-39-7 single chemical entity Component is identical to the substance 6-Benzyladenine 214-927-5 1214-39-7 N-benzyl-7H-purin-6-amine 6-Benzyladenine C12H11N5 C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3 InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France 6-Benzyladenine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine 22Oct2010 2010 doi:10.2903/j.efsa.2010.1716
+6-Benzyladenine 214-927-5 1214-39-7 single chemical entity Component is identical to the substance 6-Benzyladenine 214-927-5 1214-39-7 N-benzyl-7H-purin-6-amine 6-Benzyladenine C12H11N5 C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3 InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France 6-Benzyladenine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine 22Oct2010 2010 doi:10.2903/j.efsa.2010.1716
+6-Benzyladenine 214-927-5 1214-39-7 single chemical entity Component is identical to the substance 6-Benzyladenine 214-927-5 1214-39-7 N-benzyl-7H-purin-6-amine 6-Benzyladenine C12H11N5 C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3 InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France 6-Benzyladenine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine 22Oct2010 2010 doi:10.2903/j.efsa.2010.1716
+6-Benzyladenine 214-927-5 1214-39-7 single chemical entity Component is identical to the substance 6-Benzyladenine 214-927-5 1214-39-7 N-benzyl-7H-purin-6-amine 6-Benzyladenine C12H11N5 C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3 InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: France 6-Benzyladenine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine 22Oct2010 2010 doi:10.2903/j.efsa.2010.1716
+6-Benzyladenine 214-927-5 1214-39-7 single chemical entity Component is identical to the substance 6-Benzyladenine 214-927-5 1214-39-7 N-benzyl-7H-purin-6-amine 6-Benzyladenine C12H11N5 C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3 InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: France 6-Benzyladenine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine 22Oct2010 2010 doi:10.2903/j.efsa.2010.1716
+6-Benzyladenine 214-927-5 1214-39-7 single chemical entity Component is identical to the substance 6-Benzyladenine 214-927-5 1214-39-7 N-benzyl-7H-purin-6-amine 6-Benzyladenine C12H11N5 C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3 InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France 6-Benzyladenine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine 22Oct2010 2010 doi:10.2903/j.efsa.2010.1716
+6-Benzyladenine 214-927-5 1214-39-7 single chemical entity Component is identical to the substance 6-Benzyladenine 214-927-5 1214-39-7 N-benzyl-7H-purin-6-amine 6-Benzyladenine C12H11N5 C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3 InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France 6-Benzyladenine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine 22Oct2010 2010 doi:10.2903/j.efsa.2010.1716
+6-Benzyladenine 214-927-5 1214-39-7 single chemical entity Component is identical to the substance 6-Benzyladenine 214-927-5 1214-39-7 N-benzyl-7H-purin-6-amine 6-Benzyladenine C12H11N5 C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3 InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France 6-Benzyladenine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine 22Oct2010 2010 doi:10.2903/j.efsa.2010.1716
+6-Benzyladenine 214-927-5 1214-39-7 single chemical entity Component is identical to the substance 6-Benzyladenine 214-927-5 1214-39-7 N-benzyl-7H-purin-6-amine 6-Benzyladenine C12H11N5 C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3 InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France 6-Benzyladenine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine 22Oct2010 2010 doi:10.2903/j.efsa.2010.1716
+6-Benzyladenine 214-927-5 1214-39-7 single chemical entity Component is identical to the substance 6-Benzyladenine 214-927-5 1214-39-7 N-benzyl-7H-purin-6-amine 6-Benzyladenine C12H11N5 C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3 InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: France 6-Benzyladenine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine 22Oct2010 2010 doi:10.2903/j.efsa.2010.1716
+6-Benzyladenine 214-927-5 1214-39-7 single chemical entity Component is identical to the substance 6-Benzyladenine 214-927-5 1214-39-7 N-benzyl-7H-purin-6-amine 6-Benzyladenine C12H11N5 C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3 InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France 6-Benzyladenine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine 22Oct2010 2010 doi:10.2903/j.efsa.2010.1716
+6-Benzyladenine 214-927-5 1214-39-7 single chemical entity Component is identical to the substance 6-Benzyladenine 214-927-5 1214-39-7 N-benzyl-7H-purin-6-amine 6-Benzyladenine C12H11N5 C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3 InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France 6-Benzyladenine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine 22Oct2010 2010 doi:10.2903/j.efsa.2010.1716
+6-Benzyladenine 214-927-5 1214-39-7 single chemical entity Component is identical to the substance 6-Benzyladenine 214-927-5 1214-39-7 N-benzyl-7H-purin-6-amine 6-Benzyladenine C12H11N5 C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3 InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France 6-Benzyladenine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine 22Oct2010 2010 doi:10.2903/j.efsa.2010.1716
+6-Benzyladenine 214-927-5 1214-39-7 single chemical entity Component is identical to the substance 6-Benzyladenine 214-927-5 1214-39-7 N-benzyl-7H-purin-6-amine 6-Benzyladenine C12H11N5 C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3 InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France 6-Benzyladenine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine 22Oct2010 2010 doi:10.2903/j.efsa.2010.1716
+6-Benzyladenine 214-927-5 1214-39-7 single chemical entity Component is identical to the substance 6-Benzyladenine 214-927-5 1214-39-7 N-benzyl-7H-purin-6-amine 6-Benzyladenine C12H11N5 C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3 InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: France 6-Benzyladenine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine 22Oct2010 2010 doi:10.2903/j.efsa.2010.1716
+6-Benzyladenine 214-927-5 1214-39-7 single chemical entity Component is identical to the substance 6-Benzyladenine 214-927-5 1214-39-7 N-benzyl-7H-purin-6-amine 6-Benzyladenine C12H11N5 C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3 InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: France 6-Benzyladenine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine 22Oct2010 2010 doi:10.2903/j.efsa.2010.1716
+6-Benzyladenine 214-927-5 1214-39-7 single chemical entity Component is identical to the substance 6-Benzyladenine 214-927-5 1214-39-7 N-benzyl-7H-purin-6-amine 6-Benzyladenine C12H11N5 C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3 InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative no information RMS: France 6-Benzyladenine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine 22Oct2010 2010 doi:10.2903/j.efsa.2010.1716
+6-Benzyladenine 214-927-5 1214-39-7 single chemical entity Component is identical to the substance 6-Benzyladenine 214-927-5 1214-39-7 N-benzyl-7H-purin-6-amine 6-Benzyladenine C12H11N5 C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3 InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Positive no information RMS: France 6-Benzyladenine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine 22Oct2010 2010 doi:10.2903/j.efsa.2010.1716
+6-Benzyladenine 214-927-5 1214-39-7 single chemical entity Component is identical to the substance 6-Benzyladenine 214-927-5 1214-39-7 N-benzyl-7H-purin-6-amine 6-Benzyladenine C12H11N5 C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3 InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative no information RMS: France 6-Benzyladenine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine 22Oct2010 2010 doi:10.2903/j.efsa.2010.1716
+6-Benzyladenine 214-927-5 1214-39-7 single chemical entity Component is identical to the substance 6-Benzyladenine 214-927-5 1214-39-7 N-benzyl-7H-purin-6-amine 6-Benzyladenine C12H11N5 C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3 InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Negative no information RMS: France 6-Benzyladenine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine 22Oct2010 2010 doi:10.2903/j.efsa.2010.1716
+6-Benzyladenine 214-927-5 1214-39-7 single chemical entity Component is identical to the substance 6-Benzyladenine 214-927-5 1214-39-7 N-benzyl-7H-purin-6-amine 6-Benzyladenine C12H11N5 C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3 InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: France 6-Benzyladenine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine 22Oct2010 2010 doi:10.2903/j.efsa.2010.1716
+6-Benzyladenine 214-927-5 1214-39-7 single chemical entity Component is identical to the substance 6-Benzyladenine 214-927-5 1214-39-7 N-benzyl-7H-purin-6-amine 6-Benzyladenine C12H11N5 C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3 InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) ICR 10 Male/Female oral: unspecified 48.0000000000 h yes not applicable Negative direct evidence-cytotoxicity RMS: France 6-Benzyladenine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine 22Oct2010 2010 doi:10.2903/j.efsa.2010.1716
+6-Benzyladenine 214-927-5 1214-39-7 single chemical entity Component is identical to the substance 6-Benzyladenine 214-927-5 1214-39-7 N-benzyl-7H-purin-6-amine 6-Benzyladenine C12H11N5 C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3 InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) ICR 10 Male/Female oral: unspecified 24.0000000000 h yes not applicable Negative direct evidence-cytotoxicity RMS: France 6-Benzyladenine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine 22Oct2010 2010 doi:10.2903/j.efsa.2010.1716
+6-Benzyladenine 214-927-5 1214-39-7 single chemical entity Component is identical to the substance 6-Benzyladenine 214-927-5 1214-39-7 N-benzyl-7H-purin-6-amine 6-Benzyladenine C12H11N5 C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3 InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) ICR 10 Male/Female oral: unspecified 72.0000000000 h yes not applicable Negative direct evidence-cytotoxicity RMS: France 6-Benzyladenine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine 22Oct2010 2010 doi:10.2903/j.efsa.2010.1716
+8-Hydroxyquinoline 205-711-1 148-24-3 single chemical entity Component is a metabolite of the substance bis(8-hydroxyquinolinium) sulphate quinolin-8-ol Not in list C18H16N2O6S C1=CC2=C(C(=C1)O)N=CC=C2.C1=CC2=C(C(=C1)O)N=CC=C2.OS(=O)(=O)O InChI=1S/2C9H7NO.H2O4S/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;1-5(2,3)4/h2*1-6,11H;(H2,1,2,3,4) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Spain 8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline 28Jan2011 2011 doi:10.2903/j.efsa.2011.1964
+8-Hydroxyquinoline 205-711-1 148-24-3 single chemical entity Component is a metabolite of the substance bis(8-hydroxyquinolinium) sulphate quinolin-8-ol Not in list C18H16N2O6S C1=CC2=C(C(=C1)O)N=CC=C2.C1=CC2=C(C(=C1)O)N=CC=C2.OS(=O)(=O)O InChI=1S/2C9H7NO.H2O4S/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;1-5(2,3)4/h2*1-6,11H;(H2,1,2,3,4) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Spain 8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline 28Jan2011 2011 doi:10.2903/j.efsa.2011.1964
+8-Hydroxyquinoline 205-711-1 148-24-3 single chemical entity Component is a metabolite of the substance bis(8-hydroxyquinolinium) sulphate quinolin-8-ol Not in list C18H16N2O6S C1=CC2=C(C(=C1)O)N=CC=C2.C1=CC2=C(C(=C1)O)N=CC=C2.OS(=O)(=O)O InChI=1S/2C9H7NO.H2O4S/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;1-5(2,3)4/h2*1-6,11H;(H2,1,2,3,4) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Spain 8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline 28Jan2011 2011 doi:10.2903/j.efsa.2011.1964
+8-Hydroxyquinoline 205-711-1 148-24-3 single chemical entity Component is a metabolite of the substance bis(8-hydroxyquinolinium) sulphate quinolin-8-ol Not in list C18H16N2O6S C1=CC2=C(C(=C1)O)N=CC=C2.C1=CC2=C(C(=C1)O)N=CC=C2.OS(=O)(=O)O InChI=1S/2C9H7NO.H2O4S/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;1-5(2,3)4/h2*1-6,11H;(H2,1,2,3,4) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Spain 8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline 28Jan2011 2011 doi:10.2903/j.efsa.2011.1964
+8-Hydroxyquinoline 205-711-1 148-24-3 single chemical entity Component is a metabolite of the substance bis(8-hydroxyquinolinium) sulphate quinolin-8-ol Not in list C18H16N2O6S C1=CC2=C(C(=C1)O)N=CC=C2.C1=CC2=C(C(=C1)O)N=CC=C2.OS(=O)(=O)O InChI=1S/2C9H7NO.H2O4S/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;1-5(2,3)4/h2*1-6,11H;(H2,1,2,3,4) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Positive RMS: Spain 8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline 28Jan2011 2011 doi:10.2903/j.efsa.2011.1964
+8-Hydroxyquinoline 205-711-1 148-24-3 single chemical entity Component is a metabolite of the substance bis(8-hydroxyquinolinium) sulphate quinolin-8-ol Not in list C18H16N2O6S C1=CC2=C(C(=C1)O)N=CC=C2.C1=CC2=C(C(=C1)O)N=CC=C2.OS(=O)(=O)O InChI=1S/2C9H7NO.H2O4S/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;1-5(2,3)4/h2*1-6,11H;(H2,1,2,3,4) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: Spain 8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline 28Jan2011 2011 doi:10.2903/j.efsa.2011.1964
+8-Hydroxyquinoline 205-711-1 148-24-3 single chemical entity Component is a metabolite of the substance bis(8-hydroxyquinolinium) sulphate quinolin-8-ol Not in list C18H16N2O6S C1=CC2=C(C(=C1)O)N=CC=C2.C1=CC2=C(C(=C1)O)N=CC=C2.OS(=O)(=O)O InChI=1S/2C9H7NO.H2O4S/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;1-5(2,3)4/h2*1-6,11H;(H2,1,2,3,4) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: Spain 8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline 28Jan2011 2011 doi:10.2903/j.efsa.2011.1964
+8-Hydroxyquinoline 205-711-1 148-24-3 single chemical entity Component is a metabolite of the substance bis(8-hydroxyquinolinium) sulphate quinolin-8-ol Not in list C18H16N2O6S C1=CC2=C(C(=C1)O)N=CC=C2.C1=CC2=C(C(=C1)O)N=CC=C2.OS(=O)(=O)O InChI=1S/2C9H7NO.H2O4S/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;1-5(2,3)4/h2*1-6,11H;(H2,1,2,3,4) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Spain 8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline 28Jan2011 2011 doi:10.2903/j.efsa.2011.1964
+8-Hydroxyquinoline 205-711-1 148-24-3 single chemical entity Component is a metabolite of the substance bis(8-hydroxyquinolinium) sulphate quinolin-8-ol Not in list C18H16N2O6S C1=CC2=C(C(=C1)O)N=CC=C2.C1=CC2=C(C(=C1)O)N=CC=C2.OS(=O)(=O)O InChI=1S/2C9H7NO.H2O4S/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;1-5(2,3)4/h2*1-6,11H;(H2,1,2,3,4) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Positive RMS: Spain 8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline 28Jan2011 2011 doi:10.2903/j.efsa.2011.1964
+8-Hydroxyquinoline 205-711-1 148-24-3 single chemical entity Component is a metabolite of the substance bis(8-hydroxyquinolinium) sulphate quinolin-8-ol Not in list C18H16N2O6S C1=CC2=C(C(=C1)O)N=CC=C2.C1=CC2=C(C(=C1)O)N=CC=C2.OS(=O)(=O)O InChI=1S/2C9H7NO.H2O4S/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;1-5(2,3)4/h2*1-6,11H;(H2,1,2,3,4) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Spain 8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline 28Jan2011 2011 doi:10.2903/j.efsa.2011.1964
+8-Hydroxyquinoline 205-711-1 148-24-3 single chemical entity Component is identical to the substance 8-Hydroxyquinoline 205-711-1 148-24-3 Quinolin-8-ol Not in list C9H7NO C1=CC2=C(C(=C1)O)N=CC=C2 InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Spain 8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline 28Jan2011 2011 doi:10.2903/j.efsa.2011.1964
+8-Hydroxyquinoline 205-711-1 148-24-3 single chemical entity Component is identical to the substance 8-Hydroxyquinoline 205-711-1 148-24-3 Quinolin-8-ol Not in list C9H7NO C1=CC2=C(C(=C1)O)N=CC=C2 InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Spain 8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline 28Jan2011 2011 doi:10.2903/j.efsa.2011.1964
+8-Hydroxyquinoline 205-711-1 148-24-3 single chemical entity Component is identical to the substance 8-Hydroxyquinoline 205-711-1 148-24-3 Quinolin-8-ol Not in list C9H7NO C1=CC2=C(C(=C1)O)N=CC=C2 InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: Spain 8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline 28Jan2011 2011 doi:10.2903/j.efsa.2011.1964
+8-Hydroxyquinoline 205-711-1 148-24-3 single chemical entity Component is identical to the substance 8-Hydroxyquinoline 205-711-1 148-24-3 Quinolin-8-ol Not in list C9H7NO C1=CC2=C(C(=C1)O)N=CC=C2 InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: Spain 8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline 28Jan2011 2011 doi:10.2903/j.efsa.2011.1964
+8-Hydroxyquinoline 205-711-1 148-24-3 single chemical entity Component is identical to the substance 8-Hydroxyquinoline 205-711-1 148-24-3 Quinolin-8-ol Not in list C9H7NO C1=CC2=C(C(=C1)O)N=CC=C2 InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Positive RMS: Spain 8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline 28Jan2011 2011 doi:10.2903/j.efsa.2011.1964
+8-Hydroxyquinoline 205-711-1 148-24-3 single chemical entity Component is identical to the substance 8-Hydroxyquinoline 205-711-1 148-24-3 Quinolin-8-ol Not in list C9H7NO C1=CC2=C(C(=C1)O)N=CC=C2 InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Positive RMS: Spain 8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline 28Jan2011 2011 doi:10.2903/j.efsa.2011.1964
+8-Hydroxyquinoline 205-711-1 148-24-3 single chemical entity Component is identical to the substance 8-Hydroxyquinoline 205-711-1 148-24-3 Quinolin-8-ol Not in list C9H7NO C1=CC2=C(C(=C1)O)N=CC=C2 InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Spain 8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline 28Jan2011 2011 doi:10.2903/j.efsa.2011.1964
+8-Hydroxyquinoline 205-711-1 148-24-3 single chemical entity Component is identical to the substance 8-Hydroxyquinoline 205-711-1 148-24-3 Quinolin-8-ol Not in list C9H7NO C1=CC2=C(C(=C1)O)N=CC=C2 InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Spain 8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline 28Jan2011 2011 doi:10.2903/j.efsa.2011.1964
+8-Hydroxyquinoline 205-711-1 148-24-3 single chemical entity Component is identical to the substance 8-Hydroxyquinoline 205-711-1 148-24-3 Quinolin-8-ol Not in list C9H7NO C1=CC2=C(C(=C1)O)N=CC=C2 InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Spain 8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline 28Jan2011 2011 doi:10.2903/j.efsa.2011.1964
+8-Hydroxyquinoline 205-711-1 148-24-3 single chemical entity Component is identical to the substance 8-Hydroxyquinoline 205-711-1 148-24-3 Quinolin-8-ol Not in list C9H7NO C1=CC2=C(C(=C1)O)N=CC=C2 InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Spain 8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline 28Jan2011 2011 doi:10.2903/j.efsa.2011.1964
+8-Hydroxyquinoline 205-711-1 148-24-3 single chemical entity Component is a metabolite of the substance bis(8-hydroxyquinolinium) sulphate quinolin-8-ol Not in list C18H16N2O6S C1=CC2=C(C(=C1)O)N=CC=C2.C1=CC2=C(C(=C1)O)N=CC=C2.OS(=O)(=O)O InChI=1S/2C9H7NO.H2O4S/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;1-5(2,3)4/h2*1-6,11H;(H2,1,2,3,4) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Positive RMS: Spain 8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline 28Jan2011 2011 doi:10.2903/j.efsa.2011.1964
+8-Hydroxyquinoline 205-711-1 148-24-3 single chemical entity Component is identical to the substance 8-Hydroxyquinoline 205-711-1 148-24-3 Quinolin-8-ol Not in list C9H7NO C1=CC2=C(C(=C1)O)N=CC=C2 InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Spain 8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline 28Jan2011 2011 doi:10.2903/j.efsa.2011.1964
+8-Hydroxyquinoline 205-711-1 148-24-3 single chemical entity Component is a metabolite of the substance bis(8-hydroxyquinolinium) sulphate quinolin-8-ol Not in list C18H16N2O6S C1=CC2=C(C(=C1)O)N=CC=C2.C1=CC2=C(C(=C1)O)N=CC=C2.OS(=O)(=O)O InChI=1S/2C9H7NO.H2O4S/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;1-5(2,3)4/h2*1-6,11H;(H2,1,2,3,4) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes without Negative RMS: Spain 8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline 28Jan2011 2011 doi:10.2903/j.efsa.2011.1964
+8-Hydroxyquinoline 205-711-1 148-24-3 single chemical entity Component is identical to the substance 8-Hydroxyquinoline 205-711-1 148-24-3 Quinolin-8-ol Not in list C9H7NO C1=CC2=C(C(=C1)O)N=CC=C2 InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Positive RMS: Spain 8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline 28Jan2011 2011 doi:10.2903/j.efsa.2011.1964
+8-Hydroxyquinoline 205-711-1 148-24-3 single chemical entity Component is a metabolite of the substance bis(8-hydroxyquinolinium) sulphate quinolin-8-ol Not in list C18H16N2O6S C1=CC2=C(C(=C1)O)N=CC=C2.C1=CC2=C(C(=C1)O)N=CC=C2.OS(=O)(=O)O InChI=1S/2C9H7NO.H2O4S/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;1-5(2,3)4/h2*1-6,11H;(H2,1,2,3,4) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Spain 8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline 28Jan2011 2011 doi:10.2903/j.efsa.2011.1964
+8-Hydroxyquinoline 205-711-1 148-24-3 single chemical entity Component is a metabolite of the substance bis(8-hydroxyquinolinium) sulphate quinolin-8-ol Not in list C18H16N2O6S C1=CC2=C(C(=C1)O)N=CC=C2.C1=CC2=C(C(=C1)O)N=CC=C2.OS(=O)(=O)O InChI=1S/2C9H7NO.H2O4S/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;1-5(2,3)4/h2*1-6,11H;(H2,1,2,3,4) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Positive RMS: Spain 8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline 28Jan2011 2011 doi:10.2903/j.efsa.2011.1964
+8-Hydroxyquinoline 205-711-1 148-24-3 single chemical entity Component is identical to the substance 8-Hydroxyquinoline 205-711-1 148-24-3 Quinolin-8-ol Not in list C9H7NO C1=CC2=C(C(=C1)O)N=CC=C2 InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes with Positive RMS: Spain 8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline 28Jan2011 2011 doi:10.2903/j.efsa.2011.1964
+8-Hydroxyquinoline 205-711-1 148-24-3 single chemical entity Component is identical to the substance 8-Hydroxyquinoline 205-711-1 148-24-3 Quinolin-8-ol Not in list C9H7NO C1=CC2=C(C(=C1)O)N=CC=C2 InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes without Negative RMS: Spain 8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline 28Jan2011 2011 doi:10.2903/j.efsa.2011.1964
+8-Hydroxyquinoline 205-711-1 148-24-3 single chemical entity Component is a metabolite of the substance bis(8-hydroxyquinolinium) sulphate quinolin-8-ol Not in list C18H16N2O6S C1=CC2=C(C(=C1)O)N=CC=C2.C1=CC2=C(C(=C1)O)N=CC=C2.OS(=O)(=O)O InChI=1S/2C9H7NO.H2O4S/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;1-5(2,3)4/h2*1-6,11H;(H2,1,2,3,4) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Spain 8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline 28Jan2011 2011 doi:10.2903/j.efsa.2011.1964
+8-Hydroxyquinoline 205-711-1 148-24-3 single chemical entity Component is a metabolite of the substance bis(8-hydroxyquinolinium) sulphate quinolin-8-ol Not in list C18H16N2O6S C1=CC2=C(C(=C1)O)N=CC=C2.C1=CC2=C(C(=C1)O)N=CC=C2.OS(=O)(=O)O InChI=1S/2C9H7NO.H2O4S/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;1-5(2,3)4/h2*1-6,11H;(H2,1,2,3,4) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Spain 8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline 28Jan2011 2011 doi:10.2903/j.efsa.2011.1964
+8-Hydroxyquinoline 205-711-1 148-24-3 single chemical entity Component is identical to the substance 8-Hydroxyquinoline 205-711-1 148-24-3 Quinolin-8-ol Not in list C9H7NO C1=CC2=C(C(=C1)O)N=CC=C2 InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Spain 8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline 28Jan2011 2011 doi:10.2903/j.efsa.2011.1964
+8-Hydroxyquinoline 205-711-1 148-24-3 single chemical entity Component is identical to the substance 8-Hydroxyquinoline 205-711-1 148-24-3 Quinolin-8-ol Not in list C9H7NO C1=CC2=C(C(=C1)O)N=CC=C2 InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Spain 8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline 28Jan2011 2011 doi:10.2903/j.efsa.2011.1964
+8-Hydroxyquinoline 205-711-1 148-24-3 single chemical entity Component is identical to the substance 8-Hydroxyquinoline 205-711-1 148-24-3 Quinolin-8-ol Not in list C9H7NO C1=CC2=C(C(=C1)O)N=CC=C2 InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Spain 8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline 28Jan2011 2011 doi:10.2903/j.efsa.2011.1964
+8-Hydroxyquinoline 205-711-1 148-24-3 single chemical entity Component is a metabolite of the substance bis(8-hydroxyquinolinium) sulphate quinolin-8-ol Not in list C18H16N2O6S C1=CC2=C(C(=C1)O)N=CC=C2.C1=CC2=C(C(=C1)O)N=CC=C2.OS(=O)(=O)O InChI=1S/2C9H7NO.H2O4S/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;1-5(2,3)4/h2*1-6,11H;(H2,1,2,3,4) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes with Negative RMS: Spain 8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline 28Jan2011 2011 doi:10.2903/j.efsa.2011.1964
+8-Hydroxyquinoline 205-711-1 148-24-3 single chemical entity Component is identical to the substance 8-Hydroxyquinoline 205-711-1 148-24-3 Quinolin-8-ol Not in list C9H7NO C1=CC2=C(C(=C1)O)N=CC=C2 InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Spain 8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline 28Jan2011 2011 doi:10.2903/j.efsa.2011.1964
+8-Hydroxyquinoline 205-711-1 148-24-3 single chemical entity Component is a metabolite of the substance bis(8-hydroxyquinolinium) sulphate quinolin-8-ol Not in list C18H16N2O6S C1=CC2=C(C(=C1)O)N=CC=C2.C1=CC2=C(C(=C1)O)N=CC=C2.OS(=O)(=O)O InChI=1S/2C9H7NO.H2O4S/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;1-5(2,3)4/h2*1-6,11H;(H2,1,2,3,4) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Spain 8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline 28Jan2011 2011 doi:10.2903/j.efsa.2011.1964
+8-Hydroxyquinoline 205-711-1 148-24-3 single chemical entity Component is a metabolite of the substance bis(8-hydroxyquinolinium) sulphate quinolin-8-ol Not in list C18H16N2O6S C1=CC2=C(C(=C1)O)N=CC=C2.C1=CC2=C(C(=C1)O)N=CC=C2.OS(=O)(=O)O InChI=1S/2C9H7NO.H2O4S/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;1-5(2,3)4/h2*1-6,11H;(H2,1,2,3,4) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Positive no information RMS: Spain 8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline 28Jan2011 2011 doi:10.2903/j.efsa.2011.1964
+8-Hydroxyquinoline 205-711-1 148-24-3 single chemical entity Component is a metabolite of the substance bis(8-hydroxyquinolinium) sulphate quinolin-8-ol Not in list C18H16N2O6S C1=CC2=C(C(=C1)O)N=CC=C2.C1=CC2=C(C(=C1)O)N=CC=C2.OS(=O)(=O)O InChI=1S/2C9H7NO.H2O4S/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;1-5(2,3)4/h2*1-6,11H;(H2,1,2,3,4) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent no treatment no data Positive RMS: Spain 8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline 28Jan2011 2011 doi:10.2903/j.efsa.2011.1964
+8-Hydroxyquinoline 205-711-1 148-24-3 single chemical entity Component is identical to the substance 8-Hydroxyquinoline 205-711-1 148-24-3 Quinolin-8-ol Not in list C9H7NO C1=CC2=C(C(=C1)O)N=CC=C2 InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Positive RMS: Spain 8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline 28Jan2011 2011 doi:10.2903/j.efsa.2011.1964
+8-Hydroxyquinoline 205-711-1 148-24-3 single chemical entity Component is identical to the substance 8-Hydroxyquinoline 205-711-1 148-24-3 Quinolin-8-ol Not in list C9H7NO C1=CC2=C(C(=C1)O)N=CC=C2 InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Positive RMS: Spain 8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline 28Jan2011 2011 doi:10.2903/j.efsa.2011.1964
+8-Hydroxyquinoline 205-711-1 148-24-3 single chemical entity Component is identical to the substance 8-Hydroxyquinoline 205-711-1 148-24-3 Quinolin-8-ol Not in list C9H7NO C1=CC2=C(C(=C1)O)N=CC=C2 InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 15 Male intraperitoneal 72.0000000000 h yes not applicable Positive direct evidence-cytotoxicity$indirect evidence-systemic toxicity RMS: Spain 8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline 28Jan2011 2011 doi:10.2903/j.efsa.2011.1964
+8-Hydroxyquinoline 205-711-1 148-24-3 single chemical entity Component is identical to the substance 8-Hydroxyquinoline 205-711-1 148-24-3 Quinolin-8-ol Not in list C9H7NO C1=CC2=C(C(=C1)O)N=CC=C2 InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 15 Male intraperitoneal 48.0000000000 h yes not applicable Positive direct evidence-cytotoxicity$indirect evidence-systemic toxicity RMS: Spain 8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline 28Jan2011 2011 doi:10.2903/j.efsa.2011.1964
+8-Hydroxyquinoline 205-711-1 148-24-3 single chemical entity Component is identical to the substance 8-Hydroxyquinoline 205-711-1 148-24-3 Quinolin-8-ol Not in list C9H7NO C1=CC2=C(C(=C1)O)N=CC=C2 InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 15 Male intraperitoneal 24.0000000000 h yes not applicable Positive direct evidence-cytotoxicity$indirect evidence-systemic toxicity RMS: Spain 8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline 28Jan2011 2011 doi:10.2903/j.efsa.2011.1964
+8-Hydroxyquinoline 205-711-1 148-24-3 single chemical entity Component is identical to the substance 8-Hydroxyquinoline 205-711-1 148-24-3 Quinolin-8-ol Not in list C9H7NO C1=CC2=C(C(=C1)O)N=CC=C2 InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) B6C3F1 12 Male intraperitoneal 17.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Spain 8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline 28Jan2011 2011 doi:10.2903/j.efsa.2011.1964
+8-Hydroxyquinoline 205-711-1 148-24-3 single chemical entity Component is identical to the substance 8-Hydroxyquinoline 205-711-1 148-24-3 Quinolin-8-ol Not in list C9H7NO C1=CC2=C(C(=C1)O)N=CC=C2 InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) B6C3F1 12 Male intraperitoneal 36.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Spain 8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline 28Jan2011 2011 doi:10.2903/j.efsa.2011.1964
+8-Hydroxyquinoline 205-711-1 148-24-3 single chemical entity Component is identical to the substance 8-Hydroxyquinoline 205-711-1 148-24-3 Quinolin-8-ol Not in list C9H7NO C1=CC2=C(C(=C1)O)N=CC=C2 InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female intraperitoneal 68.0000000000 h yes not applicable Negative indirect evidence-systemic toxicity RMS: Spain 8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline 28Jan2011 2011 doi:10.2903/j.efsa.2011.1964
+8-Hydroxyquinoline 205-711-1 148-24-3 single chemical entity Component is identical to the substance 8-Hydroxyquinoline 205-711-1 148-24-3 Quinolin-8-ol Not in list C9H7NO C1=CC2=C(C(=C1)O)N=CC=C2 InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female intraperitoneal 44.0000000000 h yes not applicable Negative indirect evidence-systemic toxicity RMS: Spain 8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline 28Jan2011 2011 doi:10.2903/j.efsa.2011.1964
+8-Hydroxyquinoline 205-711-1 148-24-3 single chemical entity Component is identical to the substance 8-Hydroxyquinoline 205-711-1 148-24-3 Quinolin-8-ol Not in list C9H7NO C1=CC2=C(C(=C1)O)N=CC=C2 InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo Equivalent or similar to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) Yes Acceptable Rat (as animal) Wistar 6 Male oral: gavage 2.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Spain 8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline 28Jan2011 2011 doi:10.2903/j.efsa.2011.1964
+8-Hydroxyquinoline 205-711-1 148-24-3 single chemical entity Component is identical to the substance 8-Hydroxyquinoline 205-711-1 148-24-3 Quinolin-8-ol Not in list C9H7NO C1=CC2=C(C(=C1)O)N=CC=C2 InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo Equivalent or similar to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) Yes Acceptable Rat (as animal) Wistar 6 Male oral: gavage 12.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Spain 8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline 28Jan2011 2011 doi:10.2903/j.efsa.2011.1964
+8-Hydroxyquinoline 205-711-1 148-24-3 single chemical entity Component is identical to the substance 8-Hydroxyquinoline 205-711-1 148-24-3 Quinolin-8-ol Not in list C9H7NO C1=CC2=C(C(=C1)O)N=CC=C2 InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo Equivalent or similar to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) Yes Acceptable Rat (as animal) Wistar 6 Male oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Spain 8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline 28Jan2011 2011 doi:10.2903/j.efsa.2011.1964
+8-Hydroxyquinoline 205-711-1 148-24-3 single chemical entity Component is identical to the substance 8-Hydroxyquinoline 205-711-1 148-24-3 Quinolin-8-ol Not in list C9H7NO C1=CC2=C(C(=C1)O)N=CC=C2 InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration mammalian germ cell cytogenetic assay in vivo Equivalent or similar to OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test) Yes Acceptable House mouse (as animal) NMRI 7 Male oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Spain 8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline 28Jan2011 2011 doi:10.2903/j.efsa.2011.1964
+Abamectin 71751-41-2 mixture or formulation Component is part of a mixture or forumlation Avermectin B1a 265-610-3 65195-55-3 (2aZ,4Z,5'S,6S,6'R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17-oxo-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside Abamectin (Avermectin B1a) C48H72O14 CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The Netherlands Abamectin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi 29Jul2008 2008 doi:10.2903/j.efsa.2008.147r
+Abamectin 71751-41-2 mixture or formulation Component is part of a mixture or forumlation Avermectin B1a 265-610-3 65195-55-3 (2aZ,4Z,5'S,6S,6'R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17-oxo-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside Abamectin (Avermectin B1a) C48H72O14 CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The Netherlands Abamectin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi 29Jul2008 2008 doi:10.2903/j.efsa.2008.147r
+Abamectin 71751-41-2 mixture or formulation Component is part of a mixture or forumlation Avermectin B1a 265-610-3 65195-55-3 (2aZ,4Z,5'S,6S,6'R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17-oxo-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside Abamectin (Avermectin B1a) C48H72O14 CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: The Netherlands Abamectin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi 29Jul2008 2008 doi:10.2903/j.efsa.2008.147r
+Abamectin 71751-41-2 mixture or formulation Component is part of a mixture or forumlation Avermectin B1a 265-610-3 65195-55-3 (2aZ,4Z,5'S,6S,6'R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17-oxo-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside Abamectin (Avermectin B1a) C48H72O14 CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The Netherlands Abamectin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi 29Jul2008 2008 doi:10.2903/j.efsa.2008.147r
+Abamectin 71751-41-2 mixture or formulation Component is part of a mixture or forumlation Avermectin B1a 265-610-3 65195-55-3 (2aZ,4Z,5'S,6S,6'R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17-oxo-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside Abamectin (Avermectin B1a) C48H72O14 CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The Netherlands Abamectin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi 29Jul2008 2008 doi:10.2903/j.efsa.2008.147r
+Abamectin 71751-41-2 mixture or formulation Component is part of a mixture or forumlation Avermectin B1a 265-610-3 65195-55-3 (2aZ,4Z,5'S,6S,6'R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17-oxo-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside Abamectin (Avermectin B1a) C48H72O14 CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The Netherlands Abamectin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi 29Jul2008 2008 doi:10.2903/j.efsa.2008.147r
+Abamectin 71751-41-2 mixture or formulation Component is part of a mixture or forumlation Avermectin B1a 265-610-3 65195-55-3 (2aZ,4Z,5'S,6S,6'R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17-oxo-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside Abamectin (Avermectin B1a) C48H72O14 CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: The Netherlands Abamectin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi 29Jul2008 2008 doi:10.2903/j.efsa.2008.147r
+Abamectin 71751-41-2 mixture or formulation Component is part of a mixture or forumlation Avermectin B1a 265-610-3 65195-55-3 (2aZ,4Z,5'S,6S,6'R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17-oxo-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside Abamectin (Avermectin B1a) C48H72O14 CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The Netherlands Abamectin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi 29Jul2008 2008 doi:10.2903/j.efsa.2008.147r
+Abamectin 71751-41-2 mixture or formulation Component is part of a mixture or forumlation Avermectin B1a 265-610-3 65195-55-3 (2aZ,4Z,5'S,6S,6'R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17-oxo-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside Abamectin (Avermectin B1a) C48H72O14 CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The Netherlands Abamectin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi 29Jul2008 2008 doi:10.2903/j.efsa.2008.147r
+Abamectin 71751-41-2 mixture or formulation Component is part of a mixture or forumlation Avermectin B1a 265-610-3 65195-55-3 (2aZ,4Z,5'S,6S,6'R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17-oxo-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside Abamectin (Avermectin B1a) C48H72O14 CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The Netherlands Abamectin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi 29Jul2008 2008 doi:10.2903/j.efsa.2008.147r
+Abamectin 71751-41-2 mixture or formulation Component is part of a mixture or forumlation Avermectin B1a 265-610-3 65195-55-3 (2aZ,4Z,5'S,6S,6'R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17-oxo-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside Abamectin (Avermectin B1a) C48H72O14 CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: The Netherlands Abamectin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi 29Jul2008 2008 doi:10.2903/j.efsa.2008.147r
+Abamectin 71751-41-2 mixture or formulation Component is part of a mixture or forumlation Avermectin B1a 265-610-3 65195-55-3 (2aZ,4Z,5'S,6S,6'R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17-oxo-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside Abamectin (Avermectin B1a) C48H72O14 CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: The Netherlands Abamectin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi 29Jul2008 2008 doi:10.2903/j.efsa.2008.147r
+Abamectin 71751-41-2 mixture or formulation Component is identical to the substance Abamectin 71751-41-2 (9Z,13Z,15Z)-6'-(butan-2-yl)-19,21b-dihydroxy-5',10,12,20-tetramethyl-1-oxo-3,4,5',6',8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2'-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a) C49H74O14 CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14- organic representative compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: The Netherlands Abamectin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi 29Jul2008 2008 doi:10.2903/j.efsa.2008.147r
+Abamectin 71751-41-2 mixture or formulation Component is identical to the substance Abamectin 71751-41-2 (9Z,13Z,15Z)-6'-(butan-2-yl)-19,21b-dihydroxy-5',10,12,20-tetramethyl-1-oxo-3,4,5',6',8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2'-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a) C49H74O14 CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14- organic representative compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Negative RMS: The Netherlands Abamectin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi 29Jul2008 2008 doi:10.2903/j.efsa.2008.147r
+Abamectin 71751-41-2 mixture or formulation Component is identical to the substance Abamectin 71751-41-2 (9Z,13Z,15Z)-6'-(butan-2-yl)-19,21b-dihydroxy-5',10,12,20-tetramethyl-1-oxo-3,4,5',6',8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2'-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a) C49H74O14 CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14- organic representative compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) CD-1 Male Not reported 24.0000000000 h yes not applicable Negative RMS: The Netherlands Abamectin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi 29Jul2008 2008 doi:10.2903/j.efsa.2008.147r
+Acequinocyl 57960-19-7 single chemical entity Component is identical to the substance Acequinocyl 57960-19-7 3-dodecyl-1,4-dioxo-1,4-dihydronaphthalen-2-yl acetate Acequinocyl C24H32O4 CC(=O)OC2=C(CCCCCCCCCCCC)C(=O)c1ccccc1C2=O InChI=1S/C24H32O4/c1-3-4-5-6-7-8-9-10-11-12-17-21-22(26)19-15-13-14-16-20(19)23(27)24(21)28-18(2)25/h13-16H,3-12,17H2,1-2H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: The Netherlands Acequinocyl (Revised version of September 2007) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl. 02May2013 2013 doi:10.2903/j.efsa.2013.3212
+Acequinocyl 57960-19-7 single chemical entity Component is identical to the substance Acequinocyl 57960-19-7 3-dodecyl-1,4-dioxo-1,4-dihydronaphthalen-2-yl acetate Acequinocyl C24H32O4 CC(=O)OC2=C(CCCCCCCCCCCC)C(=O)c1ccccc1C2=O InChI=1S/C24H32O4/c1-3-4-5-6-7-8-9-10-11-12-17-21-22(26)19-15-13-14-16-20(19)23(27)24(21)28-18(2)25/h13-16H,3-12,17H2,1-2H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Negative RMS: The Netherlands Acequinocyl (Revised version of September 2007) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl. 02May2013 2013 doi:10.2903/j.efsa.2013.3212
+Acequinocyl 57960-19-7 single chemical entity Component is identical to the substance Acequinocyl 57960-19-7 3-dodecyl-1,4-dioxo-1,4-dihydronaphthalen-2-yl acetate Acequinocyl C24H32O4 CC(=O)OC2=C(CCCCCCCCCCCC)C(=O)c1ccccc1C2=O InChI=1S/C24H32O4/c1-3-4-5-6-7-8-9-10-11-12-17-21-22(26)19-15-13-14-16-20(19)23(27)24(21)28-18(2)25/h13-16H,3-12,17H2,1-2H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative no information RMS: The Netherlands Acequinocyl (Revised addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl. 02May2013 2013 doi:10.2903/j.efsa.2013.3212
+Acequinocyl 57960-19-7 single chemical entity Component is identical to the substance Acequinocyl 57960-19-7 3-dodecyl-1,4-dioxo-1,4-dihydronaphthalen-2-yl acetate Acequinocyl C24H32O4 CC(=O)OC2=C(CCCCCCCCCCCC)C(=O)c1ccccc1C2=O InChI=1S/C24H32O4/c1-3-4-5-6-7-8-9-10-11-12-17-21-22(26)19-15-13-14-16-20(19)23(27)24(21)28-18(2)25/h13-16H,3-12,17H2,1-2H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Negative no information RMS: The Netherlands Acequinocyl (Revised addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl. 02May2013 2013 doi:10.2903/j.efsa.2013.3212
+Acequinocyl 57960-19-7 single chemical entity Component is identical to the substance Acequinocyl 57960-19-7 3-dodecyl-1,4-dioxo-1,4-dihydronaphthalen-2-yl acetate Acequinocyl C24H32O4 CC(=O)OC2=C(CCCCCCCCCCCC)C(=O)c1ccccc1C2=O InChI=1S/C24H32O4/c1-3-4-5-6-7-8-9-10-11-12-17-21-22(26)19-15-13-14-16-20(19)23(27)24(21)28-18(2)25/h13-16H,3-12,17H2,1-2H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 30 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The Netherlands Acequinocyl (Revised version of September 2007) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl. 02May2013 2013 doi:10.2903/j.efsa.2013.3212
+Acequinocyl 57960-19-7 single chemical entity Component is identical to the substance Acequinocyl 57960-19-7 3-dodecyl-1,4-dioxo-1,4-dihydronaphthalen-2-yl acetate Acequinocyl C24H32O4 CC(=O)OC2=C(CCCCCCCCCCCC)C(=O)c1ccccc1C2=O InChI=1S/C24H32O4/c1-3-4-5-6-7-8-9-10-11-12-17-21-22(26)19-15-13-14-16-20(19)23(27)24(21)28-18(2)25/h13-16H,3-12,17H2,1-2H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 30 Male/Female oral: gavage 72.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The Netherlands Acequinocyl (Revised version of September 2007) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl. 02May2013 2013 doi:10.2903/j.efsa.2013.3212
+Acequinocyl 57960-19-7 single chemical entity Component is identical to the substance Acequinocyl 57960-19-7 3-dodecyl-1,4-dioxo-1,4-dihydronaphthalen-2-yl acetate Acequinocyl C24H32O4 CC(=O)OC2=C(CCCCCCCCCCCC)C(=O)c1ccccc1C2=O InChI=1S/C24H32O4/c1-3-4-5-6-7-8-9-10-11-12-17-21-22(26)19-15-13-14-16-20(19)23(27)24(21)28-18(2)25/h13-16H,3-12,17H2,1-2H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 30 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The Netherlands Acequinocyl (Revised version of September 2007) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl. 02May2013 2013 doi:10.2903/j.efsa.2013.3212
+Acequinocyl 57960-19-7 single chemical entity Component is a metabolite of the substance 2-(2-oxotetradecanoyl)benzoic acid 2-(2-oxododecanoyl)benzoic acid Not in list C19H26O4 O=C(O)c1ccccc1C(=O)C(=O)CCCCCCCCCC InChI=1/C19H26O4/c1-2-3-4-5-6-7-8-9-14-17(20)18(21)15-12-10-11-13-16(15)19(22)23/h10-13H,2-9,14H2,1H3,(H,22,23) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: The Netherlands Acequinocyl (Revised version of September 2007) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl. 02May2013 2013 doi:10.2903/j.efsa.2013.3212
+Acequinocyl 57960-19-7 single chemical entity Component is a metabolite of the substance 2-(2-oxotetradecanoyl)benzoic acid 2-(2-oxododecanoyl)benzoic acid Not in list C19H26O4 O=C(O)c1ccccc1C(=O)C(=O)CCCCCCCCCC InChI=1/C19H26O4/c1-2-3-4-5-6-7-8-9-14-17(20)18(21)15-12-10-11-13-16(15)19(22)23/h10-13H,2-9,14H2,1H3,(H,22,23) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Negative RMS: The Netherlands Acequinocyl (Revised version of September 2007) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl. 02May2013 2013 doi:10.2903/j.efsa.2013.3212
+Acequinocyl 57960-19-7 single chemical entity Component is a metabolite of the substance 2-dodecyl-3-hydroxy-1,4-naphthoquinone 2-dodecyl-3-hydroxy-1,4-naphthoquinone Not in list C22H30O3 O=C2c1ccccc1C(=O)C(/O)=C2/CCCCCCCCCCCC InChI=1/C22H30O3/c1-2-3-4-5-6-7-8-9-10-11-16-19-20(23)17-14-12-13-15-18(17)21(24)22(19)25/h12-15,25H,2-11,16H2,1H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) C57BL 5 Male oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The Netherlands Acequinocyl (Revised version of September 2007) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl. 02May2013 2013 doi:10.2903/j.efsa.2013.3212
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is identical to the substance Acibenzolar-S-methyl 135158-54-2 Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester Acybenzolar-S-methyl C8H6N2OS2 CSC(=O)C1=C2C(=CC=C1)N=NS2 InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is identical to the substance Acibenzolar-S-methyl 135158-54-2 Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester Acybenzolar-S-methyl C8H6N2OS2 CSC(=O)C1=C2C(=CC=C1)N=NS2 InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is identical to the substance Acibenzolar-S-methyl 135158-54-2 Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester Acybenzolar-S-methyl C8H6N2OS2 CSC(=O)C1=C2C(=CC=C1)N=NS2 InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Positive RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is identical to the substance Acibenzolar-S-methyl 135158-54-2 Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester Acybenzolar-S-methyl C8H6N2OS2 CSC(=O)C1=C2C(=CC=C1)N=NS2 InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is identical to the substance Acibenzolar-S-methyl 135158-54-2 Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester Acybenzolar-S-methyl C8H6N2OS2 CSC(=O)C1=C2C(=CC=C1)N=NS2 InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is identical to the substance Acibenzolar-S-methyl 135158-54-2 Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester Acybenzolar-S-methyl C8H6N2OS2 CSC(=O)C1=C2C(=CC=C1)N=NS2 InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Tif:MAGf(SPF) 10 Male/Female oral: gavage 16.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is identical to the substance Acibenzolar-S-methyl 135158-54-2 Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester Acybenzolar-S-methyl C8H6N2OS2 CSC(=O)C1=C2C(=CC=C1)N=NS2 InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Tif:MAGf(SPF) 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is identical to the substance Acibenzolar-S-methyl 135158-54-2 Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester Acybenzolar-S-methyl C8H6N2OS2 CSC(=O)C1=C2C(=CC=C1)N=NS2 InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Tif:MAGf(SPF) 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is identical to the substance Acibenzolar-S-methyl 135158-54-2 Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester Acybenzolar-S-methyl C8H6N2OS2 CSC(=O)C1=C2C(=CC=C1)N=NS2 InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Wistar 3 Male oral: gavage 16.0000000000 h yes, concurrent vehicle not applicable Negative RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is identical to the substance Acibenzolar-S-methyl 135158-54-2 Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester Acybenzolar-S-methyl C8H6N2OS2 CSC(=O)C1=C2C(=CC=C1)N=NS2 InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Wistar 3 Male oral: gavage 4.0000000000 h yes, concurrent vehicle not applicable Negative RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is a metabolite of the substance 1,2,3-benzothiadiazole-7-carboxylic acid 35272-27-6 1,2,3-benzothiadiazole-7-carboxylic acid Not in list C7H4N2O2S C1=CC(=C2C(=C1)N=NS2)C(=O)O InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Negative RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is a metabolite of the substance 1,2,3-benzothiadiazole-7-carboxylic acid 35272-27-6 1,2,3-benzothiadiazole-7-carboxylic acid Not in list C7H4N2O2S C1=CC(=C2C(=C1)N=NS2)C(=O)O InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is a metabolite of the substance 1,2,3-benzothiadiazole-7-carboxylic acid 35272-27-6 1,2,3-benzothiadiazole-7-carboxylic acid Not in list C7H4N2O2S C1=CC(=C2C(=C1)N=NS2)C(=O)O InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes with Positive RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is a metabolite of the substance 1,2,3-benzothiadiazole-7-carboxylic acid 35272-27-6 1,2,3-benzothiadiazole-7-carboxylic acid Not in list C7H4N2O2S C1=CC(=C2C(=C1)N=NS2)C(=O)O InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes without Positive RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is a metabolite of the substance 1,2,3-benzothiadiazole-7-carboxylic acid 35272-27-6 1,2,3-benzothiadiazole-7-carboxylic acid Not in list C7H4N2O2S C1=CC(=C2C(=C1)N=NS2)C(=O)O InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Ambiguous RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is a metabolite of the substance 1,2,3-benzothiadiazole-7-carboxylic acid 35272-27-6 1,2,3-benzothiadiazole-7-carboxylic acid Not in list C7H4N2O2S C1=CC(=C2C(=C1)N=NS2)C(=O)O InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is a metabolite of the substance 1,2,3-benzothiadiazole-7-carboxylic acid 35272-27-6 1,2,3-benzothiadiazole-7-carboxylic acid Not in list C7H4N2O2S C1=CC(=C2C(=C1)N=NS2)C(=O)O InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is a metabolite of the substance 1,2,3-benzothiadiazole-7-carboxylic acid 35272-27-6 1,2,3-benzothiadiazole-7-carboxylic acid Not in list C7H4N2O2S C1=CC(=C2C(=C1)N=NS2)C(=O)O InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Tif:MAGf(SPF) 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is a metabolite of the substance 1,2,3-benzothiadiazole-7-carboxylic acid 35272-27-6 1,2,3-benzothiadiazole-7-carboxylic acid Not in list C7H4N2O2S C1=CC(=C2C(=C1)N=NS2)C(=O)O InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Tif:MAGf(SPF) 10 Male/Female oral: gavage 16.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is a metabolite of the substance 1,2,3-benzothiadiazole-7-carboxylic acid 35272-27-6 1,2,3-benzothiadiazole-7-carboxylic acid Not in list C7H4N2O2S C1=CC(=C2C(=C1)N=NS2)C(=O)O InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Tif:MAGf(SPF) 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Aclonifen 277-704-1 74070-46-5 single chemical entity Component is identical to the substance Aclonifen 277-704-1 74070-46-5 2-chloro-6-nitro-3-phenoxyaniline Aclonifen C12H9ClN2O3 Clc2c(N)c(ccc2Oc1ccccc1)[N+]([O-])=O InChI=1S/C12H9ClN2O3/c13-11-10(18-8-4-2-1-3-5-8)7-6-9(12(11)14)15(16)17/h1-7H,14H2 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Germany Aclonifen 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Aclonifen 21Oct2008 2008 doi:10.2903/j.efsa.2008.149r
+Aclonifen 277-704-1 74070-46-5 single chemical entity Component is identical to the substance Aclonifen 277-704-1 74070-46-5 2-chloro-6-nitro-3-phenoxyaniline Aclonifen C12H9ClN2O3 Clc2c(N)c(ccc2Oc1ccccc1)[N+]([O-])=O InChI=1S/C12H9ClN2O3/c13-11-10(18-8-4-2-1-3-5-8)7-6-9(12(11)14)15(16)17/h1-7H,14H2 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Germany Aclonifen 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Aclonifen 21Oct2008 2008 doi:10.2903/j.efsa.2008.149r
+Aclonifen 277-704-1 74070-46-5 single chemical entity Component is identical to the substance Aclonifen 277-704-1 74070-46-5 2-chloro-6-nitro-3-phenoxyaniline Aclonifen C12H9ClN2O3 Clc2c(N)c(ccc2Oc1ccccc1)[N+]([O-])=O InChI=1S/C12H9ClN2O3/c13-11-10(18-8-4-2-1-3-5-8)7-6-9(12(11)14)15(16)17/h1-7H,14H2 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data with Negative RMS: Germany Aclonifen 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Aclonifen 21Oct2008 2008 doi:10.2903/j.efsa.2008.149r
+Aclonifen 277-704-1 74070-46-5 single chemical entity Component is identical to the substance Aclonifen 277-704-1 74070-46-5 2-chloro-6-nitro-3-phenoxyaniline Aclonifen C12H9ClN2O3 Clc2c(N)c(ccc2Oc1ccccc1)[N+]([O-])=O InChI=1S/C12H9ClN2O3/c13-11-10(18-8-4-2-1-3-5-8)7-6-9(12(11)14)15(16)17/h1-7H,14H2 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data without Negative RMS: Germany Aclonifen 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Aclonifen 21Oct2008 2008 doi:10.2903/j.efsa.2008.149r
+Aclonifen 277-704-1 74070-46-5 single chemical entity Component is identical to the substance Aclonifen 277-704-1 74070-46-5 2-chloro-6-nitro-3-phenoxyaniline Aclonifen C12H9ClN2O3 Clc2c(N)c(ccc2Oc1ccccc1)[N+]([O-])=O InChI=1S/C12H9ClN2O3/c13-11-10(18-8-4-2-1-3-5-8)7-6-9(12(11)14)15(16)17/h1-7H,14H2 organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent no treatment without Negative RMS: Germany Aclonifen 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Aclonifen 21Oct2008 2008 doi:10.2903/j.efsa.2008.149r
+Aclonifen 277-704-1 74070-46-5 single chemical entity Component is identical to the substance Aclonifen 277-704-1 74070-46-5 2-chloro-6-nitro-3-phenoxyaniline Aclonifen C12H9ClN2O3 Clc2c(N)c(ccc2Oc1ccccc1)[N+]([O-])=O InChI=1S/C12H9ClN2O3/c13-11-10(18-8-4-2-1-3-5-8)7-6-9(12(11)14)15(16)17/h1-7H,14H2 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 10 Male/Female oral: unspecified 24.0000000000 h yes not applicable Negative no evidence RMS: Germany Aclonifen 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Aclonifen 21Oct2008 2008 doi:10.2903/j.efsa.2008.149r
+Aclonifen 277-704-1 74070-46-5 single chemical entity Component is identical to the substance Aclonifen 277-704-1 74070-46-5 2-chloro-6-nitro-3-phenoxyaniline Aclonifen C12H9ClN2O3 Clc2c(N)c(ccc2Oc1ccccc1)[N+]([O-])=O InChI=1S/C12H9ClN2O3/c13-11-10(18-8-4-2-1-3-5-8)7-6-9(12(11)14)15(16)17/h1-7H,14H2 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 10 Male/Female oral: unspecified 16.0000000000 h yes not applicable Negative no evidence RMS: Germany Aclonifen 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Aclonifen 21Oct2008 2008 doi:10.2903/j.efsa.2008.149r
+Aclonifen 277-704-1 74070-46-5 single chemical entity Component is identical to the substance Aclonifen 277-704-1 74070-46-5 2-chloro-6-nitro-3-phenoxyaniline Aclonifen C12H9ClN2O3 Clc2c(N)c(ccc2Oc1ccccc1)[N+]([O-])=O InChI=1S/C12H9ClN2O3/c13-11-10(18-8-4-2-1-3-5-8)7-6-9(12(11)14)15(16)17/h1-7H,14H2 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 10 Male/Female oral: unspecified 48.0000000000 h yes not applicable Negative no evidence RMS: Germany Aclonifen 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Aclonifen 21Oct2008 2008 doi:10.2903/j.efsa.2008.149r
+Acrinathrin 101007-06-1 single chemical entity Component is identical to the substance Acrinathrin 101007-06-1 [(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate Acrinathrin C26H21F6NO5 CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Acrinathrin (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin. 19Dec2013 2013 doi:10.2903/j.efsa.2013.3469
+Acrinathrin 101007-06-1 single chemical entity Component is identical to the substance Acrinathrin 101007-06-1 [(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate Acrinathrin C26H21F6NO5 CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Acrinathrin (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin. 19Dec2013 2013 doi:10.2903/j.efsa.2013.3469
+Acrinathrin 101007-06-1 single chemical entity Component is identical to the substance Acrinathrin 101007-06-1 [(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate Acrinathrin C26H21F6NO5 CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: France Acrinathrin (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin. 19Dec2013 2013 doi:10.2903/j.efsa.2013.3469
+Acrinathrin 101007-06-1 single chemical entity Component is identical to the substance Acrinathrin 101007-06-1 [(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate Acrinathrin C26H21F6NO5 CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Acrinathrin (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin. 19Dec2013 2013 doi:10.2903/j.efsa.2013.3469
+Acrinathrin 101007-06-1 single chemical entity Component is identical to the substance Acrinathrin 101007-06-1 [(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate Acrinathrin C26H21F6NO5 CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Acrinathrin (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin. 19Dec2013 2013 doi:10.2903/j.efsa.2013.3469
+Acrinathrin 101007-06-1 single chemical entity Component is identical to the substance Acrinathrin 101007-06-1 [(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate Acrinathrin C26H21F6NO5 CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: France Acrinathrin (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin. 19Dec2013 2013 doi:10.2903/j.efsa.2013.3469
+Acrinathrin 101007-06-1 single chemical entity Component is identical to the substance Acrinathrin 101007-06-1 [(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate Acrinathrin C26H21F6NO5 CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Acrinathrin (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin. 19Dec2013 2013 doi:10.2903/j.efsa.2013.3469
+Acrinathrin 101007-06-1 single chemical entity Component is identical to the substance Acrinathrin 101007-06-1 [(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate Acrinathrin C26H21F6NO5 CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Acrinathrin (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin. 19Dec2013 2013 doi:10.2903/j.efsa.2013.3469
+Acrinathrin 101007-06-1 single chemical entity Component is identical to the substance Acrinathrin 101007-06-1 [(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate Acrinathrin C26H21F6NO5 CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: France Acrinathrin (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin. 19Dec2013 2013 doi:10.2903/j.efsa.2013.3469
+Acrinathrin 101007-06-1 single chemical entity Component is identical to the substance Acrinathrin 101007-06-1 [(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate Acrinathrin C26H21F6NO5 CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Acrinathrin (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin. 19Dec2013 2013 doi:10.2903/j.efsa.2013.3469
+Acrinathrin 101007-06-1 single chemical entity Component is identical to the substance Acrinathrin 101007-06-1 [(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate Acrinathrin C26H21F6NO5 CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Acrinathrin (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin. 19Dec2013 2013 doi:10.2903/j.efsa.2013.3469
+Acrinathrin 101007-06-1 single chemical entity Component is identical to the substance Acrinathrin 101007-06-1 [(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate Acrinathrin C26H21F6NO5 CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: France Acrinathrin (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin. 19Dec2013 2013 doi:10.2903/j.efsa.2013.3469
+Acrinathrin 101007-06-1 single chemical entity Component is identical to the substance Acrinathrin 101007-06-1 [(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate Acrinathrin C26H21F6NO5 CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) DNA-polymerase-A-proficient Not reported yes, concurrent vehicle with Negative RMS: France Acrinathrin (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin. 19Dec2013 2013 doi:10.2903/j.efsa.2013.3469
+Acrinathrin 101007-06-1 single chemical entity Component is identical to the substance Acrinathrin 101007-06-1 [(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate Acrinathrin C26H21F6NO5 CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) DNA-polymerase-A-deficient Not reported yes, concurrent vehicle with Negative RMS: France Acrinathrin (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin. 19Dec2013 2013 doi:10.2903/j.efsa.2013.3469
+Acrinathrin 101007-06-1 single chemical entity Component is identical to the substance Acrinathrin 101007-06-1 [(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate Acrinathrin C26H21F6NO5 CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) DNA-polymerase-A-deficient Not reported yes, concurrent vehicle without Negative RMS: France Acrinathrin (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin. 19Dec2013 2013 doi:10.2903/j.efsa.2013.3469
+Acrinathrin 101007-06-1 single chemical entity Component is identical to the substance Acrinathrin 101007-06-1 [(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate Acrinathrin C26H21F6NO5 CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) DNA-polymerase-A-proficient Not reported yes, concurrent vehicle without Negative RMS: France Acrinathrin (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin. 19Dec2013 2013 doi:10.2903/j.efsa.2013.3469
+Acrinathrin 101007-06-1 single chemical entity Component is identical to the substance Acrinathrin 101007-06-1 [(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate Acrinathrin C26H21F6NO5 CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: France Acrinathrin (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin. 19Dec2013 2013 doi:10.2903/j.efsa.2013.3469
+Acrinathrin 101007-06-1 single chemical entity Component is identical to the substance Acrinathrin 101007-06-1 [(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate Acrinathrin C26H21F6NO5 CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes with Positive RMS: France Acrinathrin (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin. 19Dec2013 2013 doi:10.2903/j.efsa.2013.3469
+Acrinathrin 101007-06-1 single chemical entity Component is identical to the substance Acrinathrin 101007-06-1 [(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate Acrinathrin C26H21F6NO5 CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Hamster (as animal) Chinese 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative RMS: France Acrinathrin (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin. 19Dec2013 2013 doi:10.2903/j.efsa.2013.3469
+Acrinathrin 101007-06-1 single chemical entity Component is identical to the substance Acrinathrin 101007-06-1 [(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate Acrinathrin C26H21F6NO5 CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Hamster (as animal) Chinese 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: France Acrinathrin (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin. 19Dec2013 2013 doi:10.2903/j.efsa.2013.3469
+Acrinathrin 101007-06-1 single chemical entity Component is identical to the substance Acrinathrin 101007-06-1 [(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate Acrinathrin C26H21F6NO5 CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Hamster (as animal) Chinese 10 Male/Female oral: gavage 6.0000000000 h yes, concurrent vehicle not applicable Negative RMS: France Acrinathrin (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin. 19Dec2013 2013 doi:10.2903/j.efsa.2013.3469
+Acrinathrin 101007-06-1 single chemical entity Component is identical to the substance Acrinathrin 101007-06-1 [(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate Acrinathrin C26H21F6NO5 CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: France Acrinathrin (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin. 19Dec2013 2013 doi:10.2903/j.efsa.2013.3469
+Acrinathrin 101007-06-1 single chemical entity Component is identical to the substance Acrinathrin 101007-06-1 [(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate Acrinathrin C26H21F6NO5 CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 72.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: France Acrinathrin (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin. 19Dec2013 2013 doi:10.2903/j.efsa.2013.3469
+Acrinathrin 101007-06-1 single chemical entity Component is identical to the substance Acrinathrin 101007-06-1 [(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate Acrinathrin C26H21F6NO5 CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity RMS: France Acrinathrin (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin. 19Dec2013 2013 doi:10.2903/j.efsa.2013.3469
+Acrinathrin 101007-06-1 single chemical entity Component is identical to the substance Acrinathrin 101007-06-1 [(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate Acrinathrin C26H21F6NO5 CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Sprague-Dawley 4 Male oral: gavage 14.0000000000 h yes, concurrent vehicle not applicable Negative RMS: France Acrinathrin (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin. 19Dec2013 2013 doi:10.2903/j.efsa.2013.3469
+Acrinathrin 101007-06-1 single chemical entity Component is identical to the substance Acrinathrin 101007-06-1 [(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate Acrinathrin C26H21F6NO5 CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Sprague-Dawley 4 Male oral: gavage 2.0000000000 h yes, concurrent vehicle not applicable Negative RMS: France Acrinathrin (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin. 19Dec2013 2013 doi:10.2903/j.efsa.2013.3469
+Aluminium phosphide 244-088-0 20859-73-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes without Inconclusive RMS: Germany Aluminium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.182r
+Aluminium phosphide 244-088-0 20859-73-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes with Inconclusive RMS: Germany Aluminium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.182r
+Calcium phosphide 215-142-0 1305-99-3 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes with Inconclusive RMS: Germany Calcium phosphide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide 22Oct2008 2008 doi:10.2903/j.efsa.2008.183r
+Calcium phosphide 215-142-0 1305-99-3 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes without Inconclusive RMS: Germany Calcium phosphide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide 22Oct2008 2008 doi:10.2903/j.efsa.2008.183r
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes without Inconclusive RMS: Germany Zinc phosphide 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Phosphine 232-260-8 7803-51-2 single chemical entity Component is identical to the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes with Inconclusive RMS: Germany Phosphane 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane 02Mar2012 2012 doi:10.2903/j.efsa.2012.2595
+Phosphine 232-260-8 7803-51-2 single chemical entity Component is identical to the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes without Inconclusive RMS: Germany Phosphane 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane 02Mar2012 2012 doi:10.2903/j.efsa.2012.2595
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes without Inconclusive RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes with Inconclusive RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes with Inconclusive RMS: Germany Zinc phosphide 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Inconclusive RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Phosphine 232-260-8 7803-51-2 single chemical entity Component is identical to the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Inconclusive RMS: Germany Phosphane 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane 02Mar2012 2012 doi:10.2903/j.efsa.2012.2595
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Inconclusive RMS: Germany Zinc phosphide 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Phosphine 232-260-8 7803-51-2 single chemical entity Component is identical to the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Inconclusive RMS: Germany Phosphane 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane 02Mar2012 2012 doi:10.2903/j.efsa.2012.2595
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Inconclusive RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Inconclusive RMS: Germany Zinc phosphide 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Calcium phosphide 215-142-0 1305-99-3 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Inconclusive RMS: Germany Calcium phosphide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide 22Oct2008 2008 doi:10.2903/j.efsa.2008.183r
+Calcium phosphide 215-142-0 1305-99-3 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Inconclusive RMS: Germany Calcium phosphide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide 22Oct2008 2008 doi:10.2903/j.efsa.2008.183r
+Aluminium phosphide 244-088-0 20859-73-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Inconclusive RMS: Germany Aluminium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.182r
+Aluminium phosphide 244-088-0 20859-73-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Inconclusive RMS: Germany Aluminium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.182r
+Aluminium phosphide 244-088-0 20859-73-8 single chemical entity Component is identical to the substance Aluminium phosphide 244-088-0 20859-73-8 phosphinidyne aluminum Not in list AlP [Al]#P InChI=1/Al.P/rAlP/c1-2 inorganic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) Swiss 4 No data oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Germany Aluminium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.182r
+Calcium phosphide 215-142-0 1305-99-3 single chemical entity Component is part of a group but not included in the group assessment Aluminium phosphide 244-088-0 20859-73-8 phosphinidyne aluminum Not in list AlP [Al]#P InChI=1/Al.P/rAlP/c1-2 inorganic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) Swiss 4 No data oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Germany Calcium phosphide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide 22Oct2008 2008 doi:10.2903/j.efsa.2008.183r
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is part of a group but not included in the group assessment Aluminium phosphide 244-088-0 20859-73-8 phosphinidyne aluminum Not in list AlP [Al]#P InChI=1/Al.P/rAlP/c1-2 inorganic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) Swiss 4 No data oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Germany Zinc phosphide 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is part of a group but not included in the group assessment Aluminium phosphide 244-088-0 20859-73-8 phosphinidyne aluminum Not in list AlP [Al]#P InChI=1/Al.P/rAlP/c1-2 inorganic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) Swiss 4 No data oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is part of a group but not included in the group assessment Aluminium phosphide 244-088-0 20859-73-8 phosphinidyne aluminum Not in list AlP [Al]#P InChI=1/Al.P/rAlP/c1-2 inorganic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Swiss 6 Male oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Germany Zinc phosphide 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is part of a group but not included in the group assessment Aluminium phosphide 244-088-0 20859-73-8 phosphinidyne aluminum Not in list AlP [Al]#P InChI=1/Al.P/rAlP/c1-2 inorganic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Swiss 6 Male oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Calcium phosphide 215-142-0 1305-99-3 single chemical entity Component is part of a group but not included in the group assessment Aluminium phosphide 244-088-0 20859-73-8 phosphinidyne aluminum Not in list AlP [Al]#P InChI=1/Al.P/rAlP/c1-2 inorganic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Swiss 6 Male oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Germany Calcium phosphide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide 22Oct2008 2008 doi:10.2903/j.efsa.2008.183r
+Aluminium phosphide 244-088-0 20859-73-8 single chemical entity Component is identical to the substance Aluminium phosphide 244-088-0 20859-73-8 phosphinidyne aluminum Not in list AlP [Al]#P InChI=1/Al.P/rAlP/c1-2 inorganic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Swiss 6 Male oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Germany Aluminium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.182r
+Aluminium phosphide 244-088-0 20859-73-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Balb/c 24 Male/Female inhalation: unspecified 13.0000000000 week yes, concurrent vehicle not applicable Positive indirect evidence-systemic toxicity RMS: Germany Aluminium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.182r
+Aluminium phosphide 244-088-0 20859-73-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Balb/c 20 Male/Female inhalation: unspecified 2.0000000000 week yes, concurrent vehicle not applicable Negative no evidence RMS: Germany Aluminium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.182r
+Calcium phosphide 215-142-0 1305-99-3 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Balb/c 20 Male/Female inhalation: unspecified 2.0000000000 week yes, concurrent vehicle not applicable Negative no evidence RMS: Germany Calcium phosphide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide 22Oct2008 2008 doi:10.2903/j.efsa.2008.183r
+Calcium phosphide 215-142-0 1305-99-3 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Balb/c 24 Male/Female inhalation: unspecified 13.0000000000 week yes, concurrent vehicle not applicable Positive indirect evidence-systemic toxicity RMS: Germany Calcium phosphide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide 22Oct2008 2008 doi:10.2903/j.efsa.2008.183r
+Phosphine 232-260-8 7803-51-2 single chemical entity Component is identical to the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Balb/c 24 Male/Female inhalation: unspecified 13.0000000000 week yes, concurrent vehicle not applicable Negative RMS: Germany Phosphane 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane 02Mar2012 2012 doi:10.2903/j.efsa.2012.2595
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Balb/c 24 Male/Female inhalation: unspecified 2.0000000000 week yes, concurrent vehicle not applicable Negative RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Phosphine 232-260-8 7803-51-2 single chemical entity Component is identical to the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Balb/c 20 Male/Female inhalation: unspecified 2.0000000000 week yes, concurrent vehicle not applicable Negative no evidence RMS: Germany Phosphane 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane 02Mar2012 2012 doi:10.2903/j.efsa.2012.2595
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Balb/c 24 Male/Female inhalation: unspecified 13.0000000000 week yes, concurrent vehicle not applicable Positive indirect evidence-systemic toxicity RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Balb/c 20 Male/Female inhalation: unspecified 2.0000000000 week yes, concurrent vehicle not applicable Negative no evidence RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Balb/c 20 Male/Female inhalation: unspecified 2.0000000000 week yes, concurrent vehicle not applicable Negative no evidence RMS: Germany Zinc phosphide 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Phosphine 232-260-8 7803-51-2 single chemical entity Component is identical to the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Balb/c 24 Male/Female inhalation: unspecified 13.0000000000 week yes, concurrent vehicle not applicable Positive indirect evidence-systemic toxicity RMS: Germany Phosphane 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane 02Mar2012 2012 doi:10.2903/j.efsa.2012.2595
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Balb/c 24 Male/Female inhalation: unspecified 2.0000000000 week yes, concurrent vehicle not applicable Negative RMS: Germany Zinc phosphide 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Phosphine 232-260-8 7803-51-2 single chemical entity Component is identical to the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Balb/c 24 Male/Female inhalation: unspecified 2.0000000000 week yes, concurrent vehicle not applicable Negative RMS: Germany Phosphane 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane 02Mar2012 2012 doi:10.2903/j.efsa.2012.2595
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Balb/c 24 Male/Female inhalation: unspecified 13.0000000000 week yes, concurrent vehicle not applicable Positive indirect evidence-systemic toxicity RMS: Germany Zinc phosphide 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Balb/c 24 Male/Female inhalation: unspecified 13.0000000000 week yes, concurrent vehicle not applicable Negative RMS: Germany Zinc phosphide 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Balb/c 24 Male/Female inhalation: unspecified 13.0000000000 week yes, concurrent vehicle not applicable Negative RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Phosphine 232-260-8 7803-51-2 single chemical entity Component is identical to the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Fischer344 10 Male inhalation: aerosol 14.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Germany Phosphane 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane 02Mar2012 2012 doi:10.2903/j.efsa.2012.2595
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Fischer344 10 Male inhalation: aerosol 14.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Germany Zinc phosphide 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Fischer344 10 Male inhalation: aerosol 3.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Fischer344 10 Male inhalation: aerosol 3.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Germany Zinc phosphide 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Phosphine 232-260-8 7803-51-2 single chemical entity Component is identical to the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Fischer344 10 Male inhalation: aerosol 3.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Germany Phosphane 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane 02Mar2012 2012 doi:10.2903/j.efsa.2012.2595
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Fischer344 10 Male inhalation: aerosol 14.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Calcium phosphide 215-142-0 1305-99-3 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Fischer344 10 Male inhalation: aerosol 14.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Germany Calcium phosphide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide 22Oct2008 2008 doi:10.2903/j.efsa.2008.183r
+Calcium phosphide 215-142-0 1305-99-3 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Fischer344 10 Male inhalation: aerosol 3.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Germany Calcium phosphide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide 22Oct2008 2008 doi:10.2903/j.efsa.2008.183r
+Aluminium phosphide 244-088-0 20859-73-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Fischer344 10 Male inhalation: aerosol 3.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Germany Aluminium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.182r
+Aluminium phosphide 244-088-0 20859-73-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Fischer344 10 Male inhalation: aerosol 14.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Germany Aluminium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.182r
+Aluminium phosphide 244-088-0 20859-73-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 5 Male inhalation: unspecified 24.0000000000 h yes not applicable Negative no evidence RMS: Germany Aluminium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.182r
+Aluminium phosphide 244-088-0 20859-73-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) CD-1 5 Male inhalation: unspecified 24.0000000000 h yes not applicable Negative RMS: Germany Aluminium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.182r
+Aluminium phosphide 244-088-0 20859-73-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) CD-1 5 Male inhalation: unspecified 24.0000000000 h yes not applicable Negative RMS: Germany Aluminium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.182r
+Calcium phosphide 215-142-0 1305-99-3 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) CD-1 5 Male inhalation: unspecified 24.0000000000 h yes not applicable Negative RMS: Germany Calcium phosphide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide 22Oct2008 2008 doi:10.2903/j.efsa.2008.183r
+Calcium phosphide 215-142-0 1305-99-3 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) CD-1 5 Male inhalation: unspecified 24.0000000000 h yes not applicable Negative RMS: Germany Calcium phosphide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide 22Oct2008 2008 doi:10.2903/j.efsa.2008.183r
+Calcium phosphide 215-142-0 1305-99-3 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 5 Male inhalation: unspecified 24.0000000000 h yes not applicable Negative no evidence RMS: Germany Calcium phosphide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide 22Oct2008 2008 doi:10.2903/j.efsa.2008.183r
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) CD-1 5 Male inhalation: unspecified 24.0000000000 h yes not applicable Negative RMS: Germany Zinc phosphide 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) CD-1 5 Male inhalation: unspecified 24.0000000000 h yes not applicable Negative RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) CD-1 5 Male inhalation: unspecified 24.0000000000 h yes not applicable Negative RMS: Germany Zinc phosphide 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Phosphine 232-260-8 7803-51-2 single chemical entity Component is identical to the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 5 Male inhalation: unspecified 24.0000000000 h yes not applicable Negative no evidence RMS: Germany Phosphane 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane 02Mar2012 2012 doi:10.2903/j.efsa.2012.2595
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 5 Male inhalation: unspecified 24.0000000000 h yes not applicable Negative no evidence RMS: Germany Zinc phosphide 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) CD-1 5 Male inhalation: unspecified 24.0000000000 h yes not applicable Negative RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Phosphine 232-260-8 7803-51-2 single chemical entity Component is identical to the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) CD-1 5 Male inhalation: unspecified 24.0000000000 h yes not applicable Negative RMS: Germany Phosphane 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane 02Mar2012 2012 doi:10.2903/j.efsa.2012.2595
+Phosphine 232-260-8 7803-51-2 single chemical entity Component is identical to the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) CD-1 5 Male inhalation: unspecified 24.0000000000 h yes not applicable Negative RMS: Germany Phosphane 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane 02Mar2012 2012 doi:10.2903/j.efsa.2012.2595
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 5 Male inhalation: unspecified 24.0000000000 h yes not applicable Negative no evidence RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Phosphine 232-260-8 7803-51-2 single chemical entity Component is identical to the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) B6C3F1 5 Male inhalation: unspecified 24.0000000000 h yes not applicable Negative no evidence RMS: Germany Phosphane 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane 02Mar2012 2012 doi:10.2903/j.efsa.2012.2595
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) B6C3F1 5 Male inhalation: unspecified 24.0000000000 h yes not applicable Negative RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No data Acceptable House mouse (as animal) B6C3F1 5 Male inhalation: unspecified 24.0000000000 h yes not applicable Negative RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No data Acceptable House mouse (as animal) B6C3F1 5 Male inhalation: unspecified 24.0000000000 h yes not applicable Negative RMS: Germany Zinc phosphide 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Phosphine 232-260-8 7803-51-2 single chemical entity Component is identical to the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No data Acceptable House mouse (as animal) B6C3F1 5 Male inhalation: unspecified 24.0000000000 h yes not applicable Negative RMS: Germany Phosphane 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane 02Mar2012 2012 doi:10.2903/j.efsa.2012.2595
+Phosphine 232-260-8 7803-51-2 single chemical entity Component is identical to the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No data Acceptable Rat (as animal) Fischer344 5 Male inhalation: unspecified 20.0000000000 h yes not applicable Negative RMS: Germany Phosphane 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane 02Mar2012 2012 doi:10.2903/j.efsa.2012.2595
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable Rat (as animal) Fischer344 5 Male inhalation: unspecified 20.0000000000 h yes not applicable Negative no evidence RMS: Germany Zinc phosphide 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) B6C3F1 5 Male inhalation: unspecified 24.0000000000 h yes not applicable Negative RMS: Germany Zinc phosphide 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Phosphine 232-260-8 7803-51-2 single chemical entity Component is identical to the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vivo No guideline available Not reported Not applicable Acceptable Rat (as animal) Fischer344 5 Male inhalation: unspecified 20.0000000000 h yes not applicable Negative RMS: Germany Phosphane 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane 02Mar2012 2012 doi:10.2903/j.efsa.2012.2595
+Phosphine 232-260-8 7803-51-2 single chemical entity Component is identical to the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable Rat (as animal) Fischer344 5 Male inhalation: unspecified 20.0000000000 h yes not applicable Negative no evidence RMS: Germany Phosphane 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane 02Mar2012 2012 doi:10.2903/j.efsa.2012.2595
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) B6C3F1 5 Male inhalation: unspecified 24.0000000000 h yes not applicable Negative no evidence RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Phosphine 232-260-8 7803-51-2 single chemical entity Component is identical to the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) B6C3F1 5 Male inhalation: unspecified 24.0000000000 h yes not applicable Negative RMS: Germany Phosphane 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane 02Mar2012 2012 doi:10.2903/j.efsa.2012.2595
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vivo No guideline available Not reported Not applicable Acceptable Rat (as animal) Fischer344 5 Male inhalation: unspecified 20.0000000000 h yes not applicable Negative RMS: Germany Zinc phosphide 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vivo No guideline available Not reported Not applicable Acceptable Rat (as animal) Fischer344 5 Male inhalation: unspecified 20.0000000000 h yes not applicable Negative RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No data Acceptable Rat (as animal) Fischer344 5 Male inhalation: unspecified 20.0000000000 h yes not applicable Negative RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable Rat (as animal) Fischer344 5 Male inhalation: unspecified 20.0000000000 h yes not applicable Negative no evidence RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No data Acceptable Rat (as animal) Fischer344 5 Male inhalation: unspecified 20.0000000000 h yes not applicable Negative RMS: Germany Zinc phosphide 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Calcium phosphide 215-142-0 1305-99-3 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) B6C3F1 5 Male inhalation: unspecified 24.0000000000 h yes not applicable Negative no evidence RMS: Germany Calcium phosphide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide 22Oct2008 2008 doi:10.2903/j.efsa.2008.183r
+Calcium phosphide 215-142-0 1305-99-3 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No data Acceptable Rat (as animal) Fischer344 5 Male inhalation: unspecified 20.0000000000 h yes not applicable Negative RMS: Germany Calcium phosphide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide 22Oct2008 2008 doi:10.2903/j.efsa.2008.183r
+Calcium phosphide 215-142-0 1305-99-3 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vivo No guideline available Not reported Not applicable Acceptable Rat (as animal) Fischer344 5 Male inhalation: unspecified 20.0000000000 h yes not applicable Negative RMS: Germany Calcium phosphide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide 22Oct2008 2008 doi:10.2903/j.efsa.2008.183r
+Calcium phosphide 215-142-0 1305-99-3 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) B6C3F1 5 Male inhalation: unspecified 24.0000000000 h yes not applicable Negative RMS: Germany Calcium phosphide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide 22Oct2008 2008 doi:10.2903/j.efsa.2008.183r
+Calcium phosphide 215-142-0 1305-99-3 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No data Acceptable House mouse (as animal) B6C3F1 5 Male inhalation: unspecified 24.0000000000 h yes not applicable Negative RMS: Germany Calcium phosphide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide 22Oct2008 2008 doi:10.2903/j.efsa.2008.183r
+Calcium phosphide 215-142-0 1305-99-3 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable Rat (as animal) Fischer344 5 Male inhalation: unspecified 20.0000000000 h yes not applicable Negative no evidence RMS: Germany Calcium phosphide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide 22Oct2008 2008 doi:10.2903/j.efsa.2008.183r
+Aluminium phosphide 244-088-0 20859-73-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable Rat (as animal) Fischer344 5 Male inhalation: unspecified 20.0000000000 h yes not applicable Negative no evidence RMS: Germany Aluminium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.182r
+Aluminium phosphide 244-088-0 20859-73-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) B6C3F1 5 Male inhalation: unspecified 24.0000000000 h yes not applicable Negative RMS: Germany Aluminium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.182r
+Aluminium phosphide 244-088-0 20859-73-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vivo No guideline available Not reported Not applicable Acceptable Rat (as animal) Fischer344 5 Male inhalation: unspecified 20.0000000000 h yes not applicable Negative RMS: Germany Aluminium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.182r
+Aluminium phosphide 244-088-0 20859-73-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) B6C3F1 5 Male inhalation: unspecified 24.0000000000 h yes not applicable Negative no evidence RMS: Germany Aluminium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.182r
+Aluminium phosphide 244-088-0 20859-73-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No data Acceptable House mouse (as animal) B6C3F1 5 Male inhalation: unspecified 24.0000000000 h yes not applicable Negative RMS: Germany Aluminium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.182r
+Aluminium phosphide 244-088-0 20859-73-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No data Acceptable Rat (as animal) Fischer344 5 Male inhalation: unspecified 20.0000000000 h yes not applicable Negative RMS: Germany Aluminium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.182r
+Amidosulfuron 120923-37-7 single chemical entity Component is identical to the substance Amidosulfuron 120923-37-7 1-(4,6-dimethoxypyrimidin-2-yl)-3-[methyl(methylsulfonyl)sulfamoyl]urea Amidosulfuron C9H15N5O7S2 O=C(Nc1nc(cc(OC)n1)OC)NS(=O)(=O)N(C)S(C)(=O)=O InChI=1S/C9H15N5O7S2/c1-14(22(4,16)17)23(18,19)13-9(15)12-8-10-6(20-2)5-7(11-8)21-3/h5H,1-4H3,(H2,10,11,12,13,15) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Negative RMS: Austria Amidosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron 09Nov2008 2008 doi:10.2903/j.efsa.2008.116r
+Amidosulfuron 120923-37-7 single chemical entity Component is identical to the substance Amidosulfuron 120923-37-7 1-(4,6-dimethoxypyrimidin-2-yl)-3-[methyl(methylsulfonyl)sulfamoyl]urea Amidosulfuron C9H15N5O7S2 O=C(Nc1nc(cc(OC)n1)OC)NS(=O)(=O)N(C)S(C)(=O)=O InChI=1S/C9H15N5O7S2/c1-14(22(4,16)17)23(18,19)13-9(15)12-8-10-6(20-2)5-7(11-8)21-3/h5H,1-4H3,(H2,10,11,12,13,15) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: Austria Amidosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron 09Nov2008 2008 doi:10.2903/j.efsa.2008.116r
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) B6C3F1 5 Male inhalation: unspecified 24.0000000000 h yes not applicable Negative no evidence RMS: Germany Zinc phosphide 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Amidosulfuron 120923-37-7 single chemical entity Component is identical to the substance Amidosulfuron 120923-37-7 1-(4,6-dimethoxypyrimidin-2-yl)-3-[methyl(methylsulfonyl)sulfamoyl]urea Amidosulfuron C9H15N5O7S2 O=C(Nc1nc(cc(OC)n1)OC)NS(=O)(=O)N(C)S(C)(=O)=O InChI=1S/C9H15N5O7S2/c1-14(22(4,16)17)23(18,19)13-9(15)12-8-10-6(20-2)5-7(11-8)21-3/h5H,1-4H3,(H2,10,11,12,13,15) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes with Negative RMS: Austria Amidosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron 09Nov2008 2008 doi:10.2903/j.efsa.2008.116r
+Amidosulfuron 120923-37-7 single chemical entity Component is identical to the substance Amidosulfuron 120923-37-7 1-(4,6-dimethoxypyrimidin-2-yl)-3-[methyl(methylsulfonyl)sulfamoyl]urea Amidosulfuron C9H15N5O7S2 O=C(Nc1nc(cc(OC)n1)OC)NS(=O)(=O)N(C)S(C)(=O)=O InChI=1S/C9H15N5O7S2/c1-14(22(4,16)17)23(18,19)13-9(15)12-8-10-6(20-2)5-7(11-8)21-3/h5H,1-4H3,(H2,10,11,12,13,15) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes without Negative RMS: Austria Amidosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron 09Nov2008 2008 doi:10.2903/j.efsa.2008.116r
+Amidosulfuron 120923-37-7 single chemical entity Component is identical to the substance Amidosulfuron 120923-37-7 1-(4,6-dimethoxypyrimidin-2-yl)-3-[methyl(methylsulfonyl)sulfamoyl]urea Amidosulfuron C9H15N5O7S2 O=C(Nc1nc(cc(OC)n1)OC)NS(=O)(=O)N(C)S(C)(=O)=O InChI=1S/C9H15N5O7S2/c1-14(22(4,16)17)23(18,19)13-9(15)12-8-10-6(20-2)5-7(11-8)21-3/h5H,1-4H3,(H2,10,11,12,13,15) organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Human (as organism) alveolar basal epithelial cells (A549) Not reported yes without Negative RMS: Austria Amidosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron 09Nov2008 2008 doi:10.2903/j.efsa.2008.116r
+Amidosulfuron 120923-37-7 single chemical entity Component is identical to the substance Amidosulfuron 120923-37-7 1-(4,6-dimethoxypyrimidin-2-yl)-3-[methyl(methylsulfonyl)sulfamoyl]urea Amidosulfuron C9H15N5O7S2 O=C(Nc1nc(cc(OC)n1)OC)NS(=O)(=O)N(C)S(C)(=O)=O InChI=1S/C9H15N5O7S2/c1-14(22(4,16)17)23(18,19)13-9(15)12-8-10-6(20-2)5-7(11-8)21-3/h5H,1-4H3,(H2,10,11,12,13,15) organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Human (as organism) alveolar basal epithelial cells (A549) Not reported yes with Negative RMS: Austria Amidosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron 09Nov2008 2008 doi:10.2903/j.efsa.2008.116r
+Amidosulfuron 120923-37-7 single chemical entity Component is identical to the substance Amidosulfuron 120923-37-7 1-(4,6-dimethoxypyrimidin-2-yl)-3-[methyl(methylsulfonyl)sulfamoyl]urea Amidosulfuron C9H15N5O7S2 O=C(Nc1nc(cc(OC)n1)OC)NS(=O)(=O)N(C)S(C)(=O)=O InChI=1S/C9H15N5O7S2/c1-14(22(4,16)17)23(18,19)13-9(15)12-8-10-6(20-2)5-7(11-8)21-3/h5H,1-4H3,(H2,10,11,12,13,15) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 48.0000000000 h yes not applicable Negative no evidence RMS: Austria Amidosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron 09Nov2008 2008 doi:10.2903/j.efsa.2008.116r
+Amidosulfuron 120923-37-7 single chemical entity Component is identical to the substance Amidosulfuron 120923-37-7 1-(4,6-dimethoxypyrimidin-2-yl)-3-[methyl(methylsulfonyl)sulfamoyl]urea Amidosulfuron C9H15N5O7S2 O=C(Nc1nc(cc(OC)n1)OC)NS(=O)(=O)N(C)S(C)(=O)=O InChI=1S/C9H15N5O7S2/c1-14(22(4,16)17)23(18,19)13-9(15)12-8-10-6(20-2)5-7(11-8)21-3/h5H,1-4H3,(H2,10,11,12,13,15) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 24.0000000000 h yes not applicable Negative no evidence RMS: Austria Amidosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron 09Nov2008 2008 doi:10.2903/j.efsa.2008.116r
+Amidosulfuron 120923-37-7 single chemical entity Component is identical to the substance Amidosulfuron 120923-37-7 1-(4,6-dimethoxypyrimidin-2-yl)-3-[methyl(methylsulfonyl)sulfamoyl]urea Amidosulfuron C9H15N5O7S2 O=C(Nc1nc(cc(OC)n1)OC)NS(=O)(=O)N(C)S(C)(=O)=O InChI=1S/C9H15N5O7S2/c1-14(22(4,16)17)23(18,19)13-9(15)12-8-10-6(20-2)5-7(11-8)21-3/h5H,1-4H3,(H2,10,11,12,13,15) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 72.0000000000 h yes not applicable Negative no evidence RMS: Austria Amidosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron 09Nov2008 2008 doi:10.2903/j.efsa.2008.116r
+Aluminium phosphide 244-088-0 20859-73-8 single chemical entity Component is identical to the substance Aluminium phosphide 244-088-0 20859-73-8 phosphinidyne aluminum Not in list AlP [Al]#P InChI=1/Al.P/rAlP/c1-2 inorganic compound Other Other chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) Yes Acceptable House mouse (as animal) Swiss 11 Male Not reported yes, concurrent vehicle not applicable Negative RMS: Germany Aluminium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.182r
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is part of a group but not included in the group assessment Aluminium phosphide 244-088-0 20859-73-8 phosphinidyne aluminum Not in list AlP [Al]#P InChI=1/Al.P/rAlP/c1-2 inorganic compound Other Other chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) Yes Acceptable House mouse (as animal) Swiss 11 Male Not reported yes, concurrent vehicle not applicable Negative RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is part of a group but not included in the group assessment Aluminium phosphide 244-088-0 20859-73-8 phosphinidyne aluminum Not in list AlP [Al]#P InChI=1/Al.P/rAlP/c1-2 inorganic compound Other Other chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) Yes Acceptable House mouse (as animal) Swiss 11 Male Not reported yes, concurrent vehicle not applicable Negative RMS: Germany Zinc phosphide (Addendum 1) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Aminopyralid 604-721-7 150114-71-9 single chemical entity Component is identical to the substance Aminopyralid 604-721-7 150114-71-9 4-amino-3,6-dichloropyridine-2-carboxylic acid Aminopyralid C6H4Cl2N2O2 Clc1c(nc(Cl)cc1N)C(=O)O InChI=1S/C6H4Cl2N2O2/c7-3-1-2(9)4(8)5(10-3)6(11)12/h1H,(H2,9,10)(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Aminopyralid (Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aminopyralid. 11Sep2013 2013 doi:10.2903/j.efsa.2013.3352
+Aminopyralid 604-721-7 150114-71-9 single chemical entity Component is identical to the substance Aminopyralid 604-721-7 150114-71-9 4-amino-3,6-dichloropyridine-2-carboxylic acid Aminopyralid C6H4Cl2N2O2 Clc1c(nc(Cl)cc1N)C(=O)O InChI=1S/C6H4Cl2N2O2/c7-3-1-2(9)4(8)5(10-3)6(11)12/h1H,(H2,9,10)(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Aminopyralid (Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aminopyralid. 11Sep2013 2013 doi:10.2903/j.efsa.2013.3352
+Aminopyralid 604-721-7 150114-71-9 single chemical entity Component is identical to the substance Aminopyralid 604-721-7 150114-71-9 4-amino-3,6-dichloropyridine-2-carboxylic acid Aminopyralid C6H4Cl2N2O2 Clc1c(nc(Cl)cc1N)C(=O)O InChI=1S/C6H4Cl2N2O2/c7-3-1-2(9)4(8)5(10-3)6(11)12/h1H,(H2,9,10)(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Aminopyralid (Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aminopyralid. 11Sep2013 2013 doi:10.2903/j.efsa.2013.3352
+Aminopyralid 604-721-7 150114-71-9 single chemical entity Component is identical to the substance Aminopyralid 604-721-7 150114-71-9 4-amino-3,6-dichloropyridine-2-carboxylic acid Aminopyralid C6H4Cl2N2O2 Clc1c(nc(Cl)cc1N)C(=O)O InChI=1S/C6H4Cl2N2O2/c7-3-1-2(9)4(8)5(10-3)6(11)12/h1H,(H2,9,10)(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Aminopyralid (Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aminopyralid. 11Sep2013 2013 doi:10.2903/j.efsa.2013.3352
+Aminopyralid 604-721-7 150114-71-9 single chemical entity Component is identical to the substance Aminopyralid 604-721-7 150114-71-9 4-amino-3,6-dichloropyridine-2-carboxylic acid Aminopyralid C6H4Cl2N2O2 Clc1c(nc(Cl)cc1N)C(=O)O InChI=1S/C6H4Cl2N2O2/c7-3-1-2(9)4(8)5(10-3)6(11)12/h1H,(H2,9,10)(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Aminopyralid (Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aminopyralid. 11Sep2013 2013 doi:10.2903/j.efsa.2013.3352
+Aminopyralid 604-721-7 150114-71-9 single chemical entity Component is identical to the substance Aminopyralid 604-721-7 150114-71-9 4-amino-3,6-dichloropyridine-2-carboxylic acid Aminopyralid C6H4Cl2N2O2 Clc1c(nc(Cl)cc1N)C(=O)O InChI=1S/C6H4Cl2N2O2/c7-3-1-2(9)4(8)5(10-3)6(11)12/h1H,(H2,9,10)(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Aminopyralid (Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aminopyralid. 11Sep2013 2013 doi:10.2903/j.efsa.2013.3352
+Aminopyralid 604-721-7 150114-71-9 single chemical entity Component is identical to the substance Aminopyralid 604-721-7 150114-71-9 4-amino-3,6-dichloropyridine-2-carboxylic acid Aminopyralid C6H4Cl2N2O2 Clc1c(nc(Cl)cc1N)C(=O)O InChI=1S/C6H4Cl2N2O2/c7-3-1-2(9)4(8)5(10-3)6(11)12/h1H,(H2,9,10)(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Aminopyralid (Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aminopyralid. 11Sep2013 2013 doi:10.2903/j.efsa.2013.3352
+Aminopyralid 604-721-7 150114-71-9 single chemical entity Component is identical to the substance Aminopyralid 604-721-7 150114-71-9 4-amino-3,6-dichloropyridine-2-carboxylic acid Aminopyralid C6H4Cl2N2O2 Clc1c(nc(Cl)cc1N)C(=O)O InChI=1S/C6H4Cl2N2O2/c7-3-1-2(9)4(8)5(10-3)6(11)12/h1H,(H2,9,10)(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Aminopyralid (Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aminopyralid. 11Sep2013 2013 doi:10.2903/j.efsa.2013.3352
+Aminopyralid 604-721-7 150114-71-9 single chemical entity Component is identical to the substance Aminopyralid 604-721-7 150114-71-9 4-amino-3,6-dichloropyridine-2-carboxylic acid Aminopyralid C6H4Cl2N2O2 Clc1c(nc(Cl)cc1N)C(=O)O InChI=1S/C6H4Cl2N2O2/c7-3-1-2(9)4(8)5(10-3)6(11)12/h1H,(H2,9,10)(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Aminopyralid (Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aminopyralid. 11Sep2013 2013 doi:10.2903/j.efsa.2013.3352
+Aminopyralid 604-721-7 150114-71-9 single chemical entity Component is identical to the substance Aminopyralid 604-721-7 150114-71-9 4-amino-3,6-dichloropyridine-2-carboxylic acid Aminopyralid C6H4Cl2N2O2 Clc1c(nc(Cl)cc1N)C(=O)O InChI=1S/C6H4Cl2N2O2/c7-3-1-2(9)4(8)5(10-3)6(11)12/h1H,(H2,9,10)(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Aminopyralid (Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aminopyralid. 11Sep2013 2013 doi:10.2903/j.efsa.2013.3352
+Aminopyralid 604-721-7 150114-71-9 single chemical entity Component is identical to the substance Aminopyralid 604-721-7 150114-71-9 4-amino-3,6-dichloropyridine-2-carboxylic acid Aminopyralid C6H4Cl2N2O2 Clc1c(nc(Cl)cc1N)C(=O)O InChI=1S/C6H4Cl2N2O2/c7-3-1-2(9)4(8)5(10-3)6(11)12/h1H,(H2,9,10)(H,11,12) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Rat (as animal) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Aminopyralid (Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aminopyralid. 11Sep2013 2013 doi:10.2903/j.efsa.2013.3352
+Aminopyralid 604-721-7 150114-71-9 single chemical entity Component is identical to the substance Aminopyralid 604-721-7 150114-71-9 4-amino-3,6-dichloropyridine-2-carboxylic acid Aminopyralid C6H4Cl2N2O2 Clc1c(nc(Cl)cc1N)C(=O)O InChI=1S/C6H4Cl2N2O2/c7-3-1-2(9)4(8)5(10-3)6(11)12/h1H,(H2,9,10)(H,11,12) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Rat (as animal) lymphocytes Not reported yes, concurrent vehicle without Positive RMS: The United Kingdom Aminopyralid (Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aminopyralid. 11Sep2013 2013 doi:10.2903/j.efsa.2013.3352
+Aminopyralid 604-721-7 150114-71-9 single chemical entity Component is identical to the substance Aminopyralid 604-721-7 150114-71-9 4-amino-3,6-dichloropyridine-2-carboxylic acid Aminopyralid C6H4Cl2N2O2 Clc1c(nc(Cl)cc1N)C(=O)O InChI=1S/C6H4Cl2N2O2/c7-3-1-2(9)4(8)5(10-3)6(11)12/h1H,(H2,9,10)(H,11,12) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, historical without Negative RMS: The United Kingdom Aminopyralid (Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aminopyralid. 11Sep2013 2013 doi:10.2903/j.efsa.2013.3352
+Aminopyralid 604-721-7 150114-71-9 single chemical entity Component is identical to the substance Aminopyralid 604-721-7 150114-71-9 4-amino-3,6-dichloropyridine-2-carboxylic acid Aminopyralid C6H4Cl2N2O2 Clc1c(nc(Cl)cc1N)C(=O)O InChI=1S/C6H4Cl2N2O2/c7-3-1-2(9)4(8)5(10-3)6(11)12/h1H,(H2,9,10)(H,11,12) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, historical with Negative RMS: The United Kingdom Aminopyralid (Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aminopyralid. 11Sep2013 2013 doi:10.2903/j.efsa.2013.3352
+Aminopyralid 604-721-7 150114-71-9 single chemical entity Component is identical to the substance Aminopyralid 604-721-7 150114-71-9 4-amino-3,6-dichloropyridine-2-carboxylic acid Aminopyralid C6H4Cl2N2O2 Clc1c(nc(Cl)cc1N)C(=O)O InChI=1S/C6H4Cl2N2O2/c7-3-1-2(9)4(8)5(10-3)6(11)12/h1H,(H2,9,10)(H,11,12) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Not reported 6 Male oral: gavage 24.0000000000 D yes, historical not applicable Negative no evidence RMS: The United Kingdom Aminopyralid (Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aminopyralid. 11Sep2013 2013 doi:10.2903/j.efsa.2013.3352
+Amisulbrom 348635-87-0 single chemical entity Component is identical to the substance Amisulbrom 348635-87-0 3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1,2,4-triazole-1-sulfonamide Amisulbrom C13H13BrFN5O4S2 CC1=C(C2=C(N1S(=O)(=O)C3=NN(C=N3)S(=O)(=O)N(C)C)C=C(C=C2)F)Br InChI=1S/C13H13BrFN5O4S2/c1-8-12(14)10-5-4-9(15)6-11(10)20(8)25(21,22)13-16-7-19(17-13)26(23,24)18(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: The United Kingdom Amisulbrom 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom 07Apr2014 2014 doi:10.2903/j.efsa.2014.3237
+Amisulbrom 348635-87-0 single chemical entity Component is identical to the substance Amisulbrom 348635-87-0 3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1,2,4-triazole-1-sulfonamide Amisulbrom C13H13BrFN5O4S2 CC1=C(C2=C(N1S(=O)(=O)C3=NN(C=N3)S(=O)(=O)N(C)C)C=C(C=C2)F)Br InChI=1S/C13H13BrFN5O4S2/c1-8-12(14)10-5-4-9(15)6-11(10)20(8)25(21,22)13-16-7-19(17-13)26(23,24)18(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: The United Kingdom Amisulbrom 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom 07Apr2014 2014 doi:10.2903/j.efsa.2014.3237
+Amisulbrom 348635-87-0 single chemical entity Component is identical to the substance Amisulbrom 348635-87-0 3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1,2,4-triazole-1-sulfonamide Amisulbrom C13H13BrFN5O4S2 CC1=C(C2=C(N1S(=O)(=O)C3=NN(C=N3)S(=O)(=O)N(C)C)C=C(C=C2)F)Br InChI=1S/C13H13BrFN5O4S2/c1-8-12(14)10-5-4-9(15)6-11(10)20(8)25(21,22)13-16-7-19(17-13)26(23,24)18(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes without Negative RMS: The United Kingdom Amisulbrom 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom 07Apr2014 2014 doi:10.2903/j.efsa.2014.3237
+Amisulbrom 348635-87-0 single chemical entity Component is identical to the substance Amisulbrom 348635-87-0 3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1,2,4-triazole-1-sulfonamide Amisulbrom C13H13BrFN5O4S2 CC1=C(C2=C(N1S(=O)(=O)C3=NN(C=N3)S(=O)(=O)N(C)C)C=C(C=C2)F)Br InChI=1S/C13H13BrFN5O4S2/c1-8-12(14)10-5-4-9(15)6-11(10)20(8)25(21,22)13-16-7-19(17-13)26(23,24)18(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes with Negative RMS: The United Kingdom Amisulbrom 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom 07Apr2014 2014 doi:10.2903/j.efsa.2014.3237
+Amisulbrom 348635-87-0 single chemical entity Component is identical to the substance Amisulbrom 348635-87-0 3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1,2,4-triazole-1-sulfonamide Amisulbrom C13H13BrFN5O4S2 CC1=C(C2=C(N1S(=O)(=O)C3=NN(C=N3)S(=O)(=O)N(C)C)C=C(C=C2)F)Br InChI=1S/C13H13BrFN5O4S2/c1-8-12(14)10-5-4-9(15)6-11(10)20(8)25(21,22)13-16-7-19(17-13)26(23,24)18(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 7 Male oral: gavage 48.0000000000 h yes not applicable Negative indirect evidence-systemic toxicity RMS: The United Kingdom Amisulbrom 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom 07Apr2014 2014 doi:10.2903/j.efsa.2014.3237
+Amisulbrom 348635-87-0 single chemical entity Component is identical to the substance Amisulbrom 348635-87-0 3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1,2,4-triazole-1-sulfonamide Amisulbrom C13H13BrFN5O4S2 CC1=C(C2=C(N1S(=O)(=O)C3=NN(C=N3)S(=O)(=O)N(C)C)C=C(C=C2)F)Br InChI=1S/C13H13BrFN5O4S2/c1-8-12(14)10-5-4-9(15)6-11(10)20(8)25(21,22)13-16-7-19(17-13)26(23,24)18(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 7 Male oral: gavage 24.0000000000 h yes not applicable Negative indirect evidence-systemic toxicity RMS: The United Kingdom Amisulbrom 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom 07Apr2014 2014 doi:10.2903/j.efsa.2014.3237
+Amisulbrom 348635-87-0 single chemical entity Component is identical to the substance Amisulbrom 348635-87-0 3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1,2,4-triazole-1-sulfonamide Amisulbrom C13H13BrFN5O4S2 CC1=C(C2=C(N1S(=O)(=O)C3=NN(C=N3)S(=O)(=O)N(C)C)C=C(C=C2)F)Br InChI=1S/C13H13BrFN5O4S2/c1-8-12(14)10-5-4-9(15)6-11(10)20(8)25(21,22)13-16-7-19(17-13)26(23,24)18(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Fischer344 3 Male oral: gavage 16.0000000000 h yes not applicable Negative RMS: The United Kingdom Amisulbrom 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom 07Apr2014 2014 doi:10.2903/j.efsa.2014.3237
+Amisulbrom 348635-87-0 single chemical entity Component is identical to the substance Amisulbrom 348635-87-0 3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1,2,4-triazole-1-sulfonamide Amisulbrom C13H13BrFN5O4S2 CC1=C(C2=C(N1S(=O)(=O)C3=NN(C=N3)S(=O)(=O)N(C)C)C=C(C=C2)F)Br InChI=1S/C13H13BrFN5O4S2/c1-8-12(14)10-5-4-9(15)6-11(10)20(8)25(21,22)13-16-7-19(17-13)26(23,24)18(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Fischer344 3 Male oral: gavage 2.0000000000 h yes not applicable Negative RMS: The United Kingdom Amisulbrom 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom 07Apr2014 2014 doi:10.2903/j.efsa.2014.3237
+Amisulbrom 348635-87-0 single chemical entity Component is identical to the substance Amisulbrom 348635-87-0 3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1,2,4-triazole-1-sulfonamide Amisulbrom C13H13BrFN5O4S2 CC1=C(C2=C(N1S(=O)(=O)C3=NN(C=N3)S(=O)(=O)N(C)C)C=C(C=C2)F)Br InChI=1S/C13H13BrFN5O4S2/c1-8-12(14)10-5-4-9(15)6-11(10)20(8)25(21,22)13-16-7-19(17-13)26(23,24)18(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable Rat (as animal) Fischer344 4 Female oral: gavage 4.0000000000 D yes not applicable Negative no evidence RMS: The United Kingdom Amisulbrom 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom 07Apr2014 2014 doi:10.2903/j.efsa.2014.3237
+Amisulbrom 348635-87-0 single chemical entity Component is identical to the substance Amisulbrom 348635-87-0 3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1,2,4-triazole-1-sulfonamide Amisulbrom C13H13BrFN5O4S2 CC1=C(C2=C(N1S(=O)(=O)C3=NN(C=N3)S(=O)(=O)N(C)C)C=C(C=C2)F)Br InChI=1S/C13H13BrFN5O4S2/c1-8-12(14)10-5-4-9(15)6-11(10)20(8)25(21,22)13-16-7-19(17-13)26(23,24)18(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable Rat (as animal) Fischer344 4 Female oral: gavage 3.0000000000 D yes not applicable Negative no evidence RMS: The United Kingdom Amisulbrom 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom 07Apr2014 2014 doi:10.2903/j.efsa.2014.3237
+Amisulbrom 348635-87-0 single chemical entity Component is identical to the substance Amisulbrom 348635-87-0 3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1,2,4-triazole-1-sulfonamide Amisulbrom C13H13BrFN5O4S2 CC1=C(C2=C(N1S(=O)(=O)C3=NN(C=N3)S(=O)(=O)N(C)C)C=C(C=C2)F)Br InChI=1S/C13H13BrFN5O4S2/c1-8-12(14)10-5-4-9(15)6-11(10)20(8)25(21,22)13-16-7-19(17-13)26(23,24)18(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable Rat (as animal) Fischer344 4 Female oral: gavage 5.0000000000 D yes not applicable Negative no evidence RMS: The United Kingdom Amisulbrom 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom 07Apr2014 2014 doi:10.2903/j.efsa.2014.3237
+Amisulbrom 348635-87-0 single chemical entity Component is identical to the substance Amisulbrom 348635-87-0 3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1,2,4-triazole-1-sulfonamide Amisulbrom C13H13BrFN5O4S2 CC1=C(C2=C(N1S(=O)(=O)C3=NN(C=N3)S(=O)(=O)N(C)C)C=C(C=C2)F)Br InChI=1S/C13H13BrFN5O4S2/c1-8-12(14)10-5-4-9(15)6-11(10)20(8)25(21,22)13-16-7-19(17-13)26(23,24)18(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo Equivalent or similar to OECD Guideline 489 Yes Acceptable Rat (as animal) Wistar 4 Female oral: gavage 24.0000000000 h yes not applicable Negative RMS: The United Kingdom Amisulbrom 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom 07Apr2014 2014 doi:10.2903/j.efsa.2014.3237
+Amisulbrom 348635-87-0 single chemical entity Component is identical to the substance Amisulbrom 348635-87-0 3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1,2,4-triazole-1-sulfonamide Amisulbrom C13H13BrFN5O4S2 CC1=C(C2=C(N1S(=O)(=O)C3=NN(C=N3)S(=O)(=O)N(C)C)C=C(C=C2)F)Br InChI=1S/C13H13BrFN5O4S2/c1-8-12(14)10-5-4-9(15)6-11(10)20(8)25(21,22)13-16-7-19(17-13)26(23,24)18(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo Equivalent or similar to OECD Guideline 489 Yes Acceptable Rat (as animal) Wistar 4 Female oral: gavage 3.0000000000 h yes not applicable Negative RMS: The United Kingdom Amisulbrom 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom 07Apr2014 2014 doi:10.2903/j.efsa.2014.3237
+Amisulbrom 348635-87-0 single chemical entity Component is identical to the substance Amisulbrom 348635-87-0 3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1,2,4-triazole-1-sulfonamide Amisulbrom C13H13BrFN5O4S2 CC1=C(C2=C(N1S(=O)(=O)C3=NN(C=N3)S(=O)(=O)N(C)C)C=C(C=C2)F)Br InChI=1S/C13H13BrFN5O4S2/c1-8-12(14)10-5-4-9(15)6-11(10)20(8)25(21,22)13-16-7-19(17-13)26(23,24)18(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo Equivalent or similar to OECD Guideline 489 Yes Acceptable House mouse (as animal) CD-1 4 Male oral: gavage 3.0000000000 h yes not applicable Negative RMS: The United Kingdom Amisulbrom 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom 07Apr2014 2014 doi:10.2903/j.efsa.2014.3237
+Amisulbrom 348635-87-0 single chemical entity Component is identical to the substance Amisulbrom 348635-87-0 3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1,2,4-triazole-1-sulfonamide Amisulbrom C13H13BrFN5O4S2 CC1=C(C2=C(N1S(=O)(=O)C3=NN(C=N3)S(=O)(=O)N(C)C)C=C(C=C2)F)Br InChI=1S/C13H13BrFN5O4S2/c1-8-12(14)10-5-4-9(15)6-11(10)20(8)25(21,22)13-16-7-19(17-13)26(23,24)18(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo Equivalent or similar to OECD Guideline 489 Yes Acceptable House mouse (as animal) CD-1 4 Male oral: gavage 24.0000000000 h yes not applicable Negative RMS: The United Kingdom Amisulbrom 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom 07Apr2014 2014 doi:10.2903/j.efsa.2014.3237
+Amisulbrom 348635-87-0 single chemical entity Component is identical to the substance Amisulbrom 348635-87-0 3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1,2,4-triazole-1-sulfonamide Amisulbrom C13H13BrFN5O4S2 CC1=C(C2=C(N1S(=O)(=O)C3=NN(C=N3)S(=O)(=O)N(C)C)C=C(C=C2)F)Br InChI=1S/C13H13BrFN5O4S2/c1-8-12(14)10-5-4-9(15)6-11(10)20(8)25(21,22)13-16-7-19(17-13)26(23,24)18(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo Equivalent or similar to OECD Guideline 489 Yes Acceptable Rat (as animal) Wistar 4 Female oral: gavage 3.0000000000 h yes not applicable Negative RMS: The United Kingdom Amisulbrom 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom 07Apr2014 2014 doi:10.2903/j.efsa.2014.3237
+Amisulbrom 348635-87-0 single chemical entity Component is identical to the substance Amisulbrom 348635-87-0 3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1,2,4-triazole-1-sulfonamide Amisulbrom C13H13BrFN5O4S2 CC1=C(C2=C(N1S(=O)(=O)C3=NN(C=N3)S(=O)(=O)N(C)C)C=C(C=C2)F)Br InChI=1S/C13H13BrFN5O4S2/c1-8-12(14)10-5-4-9(15)6-11(10)20(8)25(21,22)13-16-7-19(17-13)26(23,24)18(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo Equivalent or similar to OECD Guideline 489 Yes Acceptable Rat (as animal) Wistar 4 Female oral: gavage 24.0000000000 h yes not applicable Negative RMS: The United Kingdom Amisulbrom 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom 07Apr2014 2014 doi:10.2903/j.efsa.2014.3237
+Amisulbrom 348635-87-0 single chemical entity Component is identical to the substance Amisulbrom 348635-87-0 3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1,2,4-triazole-1-sulfonamide Amisulbrom C13H13BrFN5O4S2 CC1=C(C2=C(N1S(=O)(=O)C3=NN(C=N3)S(=O)(=O)N(C)C)C=C(C=C2)F)Br InChI=1S/C13H13BrFN5O4S2/c1-8-12(14)10-5-4-9(15)6-11(10)20(8)25(21,22)13-16-7-19(17-13)26(23,24)18(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 6 Male intraperitoneal 24.0000000000 h yes not applicable Negative direct evidence-cytotoxicity$indirect evidence-systemic toxicity RMS: The United Kingdom Amisulbrom 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom 07Apr2014 2014 doi:10.2903/j.efsa.2014.3237
+Amisulbrom 348635-87-0 single chemical entity Component is identical to the substance Amisulbrom 348635-87-0 3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1,2,4-triazole-1-sulfonamide Amisulbrom C13H13BrFN5O4S2 CC1=C(C2=C(N1S(=O)(=O)C3=NN(C=N3)S(=O)(=O)N(C)C)C=C(C=C2)F)Br InChI=1S/C13H13BrFN5O4S2/c1-8-12(14)10-5-4-9(15)6-11(10)20(8)25(21,22)13-16-7-19(17-13)26(23,24)18(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 6 Male oral: gavage 24.0000000000 h yes not applicable Negative no evidence RMS: The United Kingdom Amisulbrom 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom 07Apr2014 2014 doi:10.2903/j.efsa.2014.3237
+Azadirachtin A 11141-17-6 complex product: derived from botanical sources Component is the active ingredient of the mixture or formulation Azadirachtin extract (Trifolio-M GmbH source) methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate Not in list C35H44O16 C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+ organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Positive RMS: Germany Azadirachtin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin 17Mar2011 2011 doi:10.2903/j.efsa.2011.1858
+Azadirachtin A 11141-17-6 complex product: derived from botanical sources Component is the active ingredient of the mixture or formulation Azadirachtin extract (Trifolio-M GmbH source) methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate Not in list C35H44O16 C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+ organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Positive RMS: Germany Azadirachtin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin 17Mar2011 2011 doi:10.2903/j.efsa.2011.1858
+Azadirachtin A 11141-17-6 complex product: derived from botanical sources Component is the active ingredient of the mixture or formulation Azadirachtin extract (Trifolio-M GmbH source) methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate Not in list C35H44O16 C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+ organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Germany Azadirachtin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin 17Mar2011 2011 doi:10.2903/j.efsa.2011.1858
+Azadirachtin A 11141-17-6 complex product: derived from botanical sources Component is the active ingredient of the mixture or formulation Azadirachtin extract (Trifolio-M GmbH source) methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate Not in list C35H44O16 C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+ organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Germany Azadirachtin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin 17Mar2011 2011 doi:10.2903/j.efsa.2011.1858
+Azadirachtin A 11141-17-6 complex product: derived from botanical sources Component is the active ingredient of the mixture or formulation Azadirachtin extract (Trifolio-M GmbH source) methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate Not in list C35H44O16 C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+ organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity RMS: Germany Azadirachtin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin 17Mar2011 2011 doi:10.2903/j.efsa.2011.1858
+Azadirachtin A 11141-17-6 complex product: derived from botanical sources Component is the active ingredient of the mixture or formulation Azadirachtin extract (Trifolio-M GmbH source) methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate Not in list C35H44O16 C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+ organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 72.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity RMS: Germany Azadirachtin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin 17Mar2011 2011 doi:10.2903/j.efsa.2011.1858
+Azadirachtin A 11141-17-6 complex product: derived from botanical sources Component is the active ingredient of the mixture or formulation Azadirachtin extract (Trifolio-M GmbH source) methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate Not in list C35H44O16 C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+ organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity RMS: Germany Azadirachtin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin 17Mar2011 2011 doi:10.2903/j.efsa.2011.1858
+Azadirachtin A 11141-17-6 complex product: microorganisms or derived from microorganisms Component is the active ingredient of the mixture or formulation Azadirachtin extract (Sipcam S.p.A source) methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate Not in list C35H44O16 C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+ organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Positive RMS: Germany Azadirachtin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin 17Mar2011 2011 doi:10.2903/j.efsa.2011.1858
+Azadirachtin A 11141-17-6 complex product: microorganisms or derived from microorganisms Component is the active ingredient of the mixture or formulation Azadirachtin extract (Sipcam S.p.A source) methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate Not in list C35H44O16 C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+ organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Positive RMS: Germany Azadirachtin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin 17Mar2011 2011 doi:10.2903/j.efsa.2011.1858
+Azadirachtin A 11141-17-6 complex product: microorganisms or derived from microorganisms Component is the active ingredient of the mixture or formulation Azadirachtin extract (Sipcam S.p.A source) methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate Not in list C35H44O16 C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+ organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Germany Azadirachtin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin 17Mar2011 2011 doi:10.2903/j.efsa.2011.1858
+Azadirachtin A 11141-17-6 complex product: microorganisms or derived from microorganisms Component is the active ingredient of the mixture or formulation Azadirachtin extract (Sipcam S.p.A source) methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate Not in list C35H44O16 C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+ organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Germany Azadirachtin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin 17Mar2011 2011 doi:10.2903/j.efsa.2011.1858
+Azadirachtin A 11141-17-6 complex product: microorganisms or derived from microorganisms Component is the active ingredient of the mixture or formulation Azadirachtin extract (Sipcam S.p.A source) methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate Not in list C35H44O16 C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+ organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 72.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity$indirect evidence-systemic toxicity RMS: Germany Azadirachtin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin 17Mar2011 2011 doi:10.2903/j.efsa.2011.1858
+Azadirachtin A 11141-17-6 complex product: microorganisms or derived from microorganisms Component is the active ingredient of the mixture or formulation Azadirachtin extract (Sipcam S.p.A source) methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate Not in list C35H44O16 C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+ organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity$indirect evidence-systemic toxicity RMS: Germany Azadirachtin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin 17Mar2011 2011 doi:10.2903/j.efsa.2011.1858
+Azadirachtin A 11141-17-6 complex product: microorganisms or derived from microorganisms Component is the active ingredient of the mixture or formulation Azadirachtin extract (Sipcam S.p.A source) methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate Not in list C35H44O16 C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+ organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity$indirect evidence-systemic toxicity RMS: Germany Azadirachtin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin 17Mar2011 2011 doi:10.2903/j.efsa.2011.1858
+Azadirachtin A 11141-17-6 complex product: derived from botanical sources Component is the active ingredient of the mixture or formulation Azadirachtin extract (Mitsui AgriScience International S.A/B.V source) methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate Not in list C35H44O16 C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+ organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Germany Azadirachtin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin 17Mar2011 2011 doi:10.2903/j.efsa.2011.1858
+Azadirachtin A 11141-17-6 complex product: derived from botanical sources Component is the active ingredient of the mixture or formulation Azadirachtin extract (Mitsui AgriScience International S.A/B.V source) methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate Not in list C35H44O16 C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+ organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Positive RMS: Germany Azadirachtin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin 17Mar2011 2011 doi:10.2903/j.efsa.2011.1858
+Azimsulfuron 601-676-5 120162-55-2 single chemical entity Component is identical to the substance Azimsulfuron 601-676-5 120162-55-2 N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide Azimsulfuron C13H16N10O5S Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(OC)cc(OC)n3 InChI=1S/C13H16N10O5S/c1-22-11(7(6-14-22)10-18-21-23(2)19-10)29(25,26)20-13(24)17-12-15-8(27-3)5-9(16-12)28-4/h5-6H,1-4H3,(H2,15,16,17,20,24) organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Slovenia Azimsulfuron (Corrigendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron 26Mar2010 2010 doi:10.2903/j.efsa.2010.1554
+Azimsulfuron 601-676-5 120162-55-2 single chemical entity Component is a metabolite of the substance N-[[(4-hydroxy-6-methoxypyrimidin-2-yl)amino]carbonyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide N-[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide Not in list C12H14N10O5S Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(O)cc(OC)n3 InChI=1S/C12H14N10O5S/c1-21-10(6(5-13-21)9-17-20-22(2)18-9)28(25,26)19-12(24)16-11-14-7(23)4-8(15-11)27-3/h4-5H,1-3H3,(H3,14,15,16,19,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Slovenia Azimsulfuron (Corrigendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron 26Mar2010 2010 doi:10.2903/j.efsa.2010.1554
+Azimsulfuron 601-676-5 120162-55-2 single chemical entity Component is a metabolite of the substance N-[[(4-hydroxy-6-methoxypyrimidin-2-yl)amino]carbonyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide N-[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide Not in list C12H14N10O5S Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(O)cc(OC)n3 InChI=1S/C12H14N10O5S/c1-21-10(6(5-13-21)9-17-20-22(2)18-9)28(25,26)19-12(24)16-11-14-7(23)4-8(15-11)27-3/h4-5H,1-3H3,(H3,14,15,16,19,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Slovenia Azimsulfuron (Corrigendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron 26Mar2010 2010 doi:10.2903/j.efsa.2010.1554
+Azimsulfuron 601-676-5 120162-55-2 single chemical entity Component is a metabolite of the substance N-[[(4-hydroxy-6-methoxypyrimidin-2-yl)amino]carbonyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide N-[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide Not in list C12H14N10O5S Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(O)cc(OC)n3 InChI=1S/C12H14N10O5S/c1-21-10(6(5-13-21)9-17-20-22(2)18-9)28(25,26)19-12(24)16-11-14-7(23)4-8(15-11)27-3/h4-5H,1-3H3,(H3,14,15,16,19,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Sweden - CoRMS: Slovenia Azimsulfuron (Corrigendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron 26Mar2010 2010 doi:10.2903/j.efsa.2010.1554
+Azimsulfuron 601-676-5 120162-55-2 single chemical entity Component is a metabolite of the substance N-[[(4-hydroxy-6-methoxypyrimidin-2-yl)amino]carbonyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide N-[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide Not in list C12H14N10O5S Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(O)cc(OC)n3 InChI=1S/C12H14N10O5S/c1-21-10(6(5-13-21)9-17-20-22(2)18-9)28(25,26)19-12(24)16-11-14-7(23)4-8(15-11)27-3/h4-5H,1-3H3,(H3,14,15,16,19,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Slovenia Azimsulfuron (Corrigendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron 26Mar2010 2010 doi:10.2903/j.efsa.2010.1554
+Azimsulfuron 601-676-5 120162-55-2 single chemical entity Component is a metabolite of the substance N-[[(4-hydroxy-6-methoxypyrimidin-2-yl)amino]carbonyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide N-[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide Not in list C12H14N10O5S Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(O)cc(OC)n3 InChI=1S/C12H14N10O5S/c1-21-10(6(5-13-21)9-17-20-22(2)18-9)28(25,26)19-12(24)16-11-14-7(23)4-8(15-11)27-3/h4-5H,1-3H3,(H3,14,15,16,19,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes with Negative RMS: Sweden - CoRMS: Slovenia Azimsulfuron (Corrigendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron 26Mar2010 2010 doi:10.2903/j.efsa.2010.1554
+Azimsulfuron 601-676-5 120162-55-2 single chemical entity Component is a metabolite of the substance N-[[(4-hydroxy-6-methoxypyrimidin-2-yl)amino]carbonyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide N-[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide Not in list C12H14N10O5S Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(O)cc(OC)n3 InChI=1S/C12H14N10O5S/c1-21-10(6(5-13-21)9-17-20-22(2)18-9)28(25,26)19-12(24)16-11-14-7(23)4-8(15-11)27-3/h4-5H,1-3H3,(H3,14,15,16,19,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Slovenia Azimsulfuron (Corrigendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron 26Mar2010 2010 doi:10.2903/j.efsa.2010.1554
+Azimsulfuron 601-676-5 120162-55-2 single chemical entity Component is a metabolite of the substance N-[[(4-hydroxy-6-methoxypyrimidin-2-yl)amino]carbonyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide N-[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide Not in list C12H14N10O5S Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(O)cc(OC)n3 InChI=1S/C12H14N10O5S/c1-21-10(6(5-13-21)9-17-20-22(2)18-9)28(25,26)19-12(24)16-11-14-7(23)4-8(15-11)27-3/h4-5H,1-3H3,(H3,14,15,16,19,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Sweden - CoRMS: Slovenia Azimsulfuron (Corrigendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron 26Mar2010 2010 doi:10.2903/j.efsa.2010.1554
+Azimsulfuron 601-676-5 120162-55-2 single chemical entity Component is a metabolite of the substance N-[[(4-hydroxy-6-methoxypyrimidin-2-yl)amino]carbonyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide N-[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide Not in list C12H14N10O5S Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(O)cc(OC)n3 InChI=1S/C12H14N10O5S/c1-21-10(6(5-13-21)9-17-20-22(2)18-9)28(25,26)19-12(24)16-11-14-7(23)4-8(15-11)27-3/h4-5H,1-3H3,(H3,14,15,16,19,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Slovenia Azimsulfuron (Corrigendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron 26Mar2010 2010 doi:10.2903/j.efsa.2010.1554
+Azimsulfuron 601-676-5 120162-55-2 single chemical entity Component is a metabolite of the substance N-[[(4-hydroxy-6-methoxypyrimidin-2-yl)amino]carbonyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide N-[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide Not in list C12H14N10O5S Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(O)cc(OC)n3 InChI=1S/C12H14N10O5S/c1-21-10(6(5-13-21)9-17-20-22(2)18-9)28(25,26)19-12(24)16-11-14-7(23)4-8(15-11)27-3/h4-5H,1-3H3,(H3,14,15,16,19,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Slovenia Azimsulfuron (Corrigendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron 26Mar2010 2010 doi:10.2903/j.efsa.2010.1554
+Azimsulfuron 601-676-5 120162-55-2 single chemical entity Component is a metabolite of the substance N-[[(4-hydroxy-6-methoxypyrimidin-2-yl)amino]carbonyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide N-[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide Not in list C12H14N10O5S Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(O)cc(OC)n3 InChI=1S/C12H14N10O5S/c1-21-10(6(5-13-21)9-17-20-22(2)18-9)28(25,26)19-12(24)16-11-14-7(23)4-8(15-11)27-3/h4-5H,1-3H3,(H3,14,15,16,19,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Slovenia Azimsulfuron (Corrigendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron 26Mar2010 2010 doi:10.2903/j.efsa.2010.1554
+Azimsulfuron 601-676-5 120162-55-2 single chemical entity Component is a metabolite of the substance 2-Amino-4,6-dimethoxypyrimidine 252-969-6 36315-01-2 4,6-Dimethoxypyrimidin-2-amine Not in list C6H9N3O2 COC1=CC(=NC(=N1)N)OC InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Slovenia Azimsulfuron (Corrigendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron 26Mar2010 2010 doi:10.2903/j.efsa.2010.1554
+Azimsulfuron 601-676-5 120162-55-2 single chemical entity Component is a metabolite of the substance 2-Amino-4,6-dimethoxypyrimidine 252-969-6 36315-01-2 4,6-Dimethoxypyrimidin-2-amine Not in list C6H9N3O2 COC1=CC(=NC(=N1)N)OC InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Slovenia Azimsulfuron (Corrigendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron 26Mar2010 2010 doi:10.2903/j.efsa.2010.1554
+Azimsulfuron 601-676-5 120162-55-2 single chemical entity Component is a metabolite of the substance 2-Amino-4,6-dimethoxypyrimidine 252-969-6 36315-01-2 4,6-Dimethoxypyrimidin-2-amine Not in list C6H9N3O2 COC1=CC(=NC(=N1)N)OC InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Slovenia Azimsulfuron (Corrigendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron 26Mar2010 2010 doi:10.2903/j.efsa.2010.1554
+Azimsulfuron 601-676-5 120162-55-2 single chemical entity Component is a metabolite of the substance 2-Amino-4,6-dimethoxypyrimidine 252-969-6 36315-01-2 4,6-Dimethoxypyrimidin-2-amine Not in list C6H9N3O2 COC1=CC(=NC(=N1)N)OC InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Slovenia Azimsulfuron (Corrigendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron 26Mar2010 2010 doi:10.2903/j.efsa.2010.1554
+Azimsulfuron 601-676-5 120162-55-2 single chemical entity Component is a metabolite of the substance 2-Amino-4,6-dimethoxypyrimidine 252-969-6 36315-01-2 4,6-Dimethoxypyrimidin-2-amine Not in list C6H9N3O2 COC1=CC(=NC(=N1)N)OC InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Slovenia Azimsulfuron (Corrigendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron 26Mar2010 2010 doi:10.2903/j.efsa.2010.1554
+Azimsulfuron 601-676-5 120162-55-2 single chemical entity Component is a metabolite of the substance 2-Amino-4,6-dimethoxypyrimidine 252-969-6 36315-01-2 4,6-Dimethoxypyrimidin-2-amine Not in list C6H9N3O2 COC1=CC(=NC(=N1)N)OC InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Slovenia Azimsulfuron (Corrigendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron 26Mar2010 2010 doi:10.2903/j.efsa.2010.1554
+Azimsulfuron 601-676-5 120162-55-2 single chemical entity Component is a metabolite of the substance 2-Amino-4,6-dimethoxypyrimidine 252-969-6 36315-01-2 4,6-Dimethoxypyrimidin-2-amine Not in list C6H9N3O2 COC1=CC(=NC(=N1)N)OC InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Slovenia Azimsulfuron (Corrigendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron 26Mar2010 2010 doi:10.2903/j.efsa.2010.1554
+Azimsulfuron 601-676-5 120162-55-2 single chemical entity Component is a metabolite of the substance 2-Amino-4,6-dimethoxypyrimidine 252-969-6 36315-01-2 4,6-Dimethoxypyrimidin-2-amine Not in list C6H9N3O2 COC1=CC(=NC(=N1)N)OC InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Slovenia Azimsulfuron (Corrigendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron 26Mar2010 2010 doi:10.2903/j.efsa.2010.1554
+Azimsulfuron 601-676-5 120162-55-2 single chemical entity Component is a metabolite of the substance 2-Amino-4,6-dimethoxypyrimidine 252-969-6 36315-01-2 4,6-Dimethoxypyrimidin-2-amine Not in list C6H9N3O2 COC1=CC(=NC(=N1)N)OC InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Slovenia Azimsulfuron (Corrigendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron 26Mar2010 2010 doi:10.2903/j.efsa.2010.1554
+Azimsulfuron 601-676-5 120162-55-2 single chemical entity Component is a metabolite of the substance 2-Amino-4,6-dimethoxypyrimidine 252-969-6 36315-01-2 4,6-Dimethoxypyrimidin-2-amine Not in list C6H9N3O2 COC1=CC(=NC(=N1)N)OC InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Slovenia Azimsulfuron (Corrigendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron 26Mar2010 2010 doi:10.2903/j.efsa.2010.1554
+Azimsulfuron 601-676-5 120162-55-2 single chemical entity Component is a metabolite of the substance 1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide 1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide Not in list C6H9N7O2S Cn1nc(nn1)c2cnn(C)c2S(N)(=O)=O InChI=1/C6H9N7O2S/c1-12-6(16(7,14)15)4(3-8-12)5-9-11-13(2)10-5/h3H,1-2H3,(H2,7,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Slovenia Azimsulfuron (Corrigendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron 26Mar2010 2010 doi:10.2903/j.efsa.2010.1554
+Azimsulfuron 601-676-5 120162-55-2 single chemical entity Component is a metabolite of the substance 1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide 1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide Not in list C6H9N7O2S Cn1nc(nn1)c2cnn(C)c2S(N)(=O)=O InChI=1/C6H9N7O2S/c1-12-6(16(7,14)15)4(3-8-12)5-9-11-13(2)10-5/h3H,1-2H3,(H2,7,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Sweden - CoRMS: Slovenia Azimsulfuron (Corrigendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron 26Mar2010 2010 doi:10.2903/j.efsa.2010.1554
+Azimsulfuron 601-676-5 120162-55-2 single chemical entity Component is a metabolite of the substance 1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide 1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide Not in list C6H9N7O2S Cn1nc(nn1)c2cnn(C)c2S(N)(=O)=O InChI=1/C6H9N7O2S/c1-12-6(16(7,14)15)4(3-8-12)5-9-11-13(2)10-5/h3H,1-2H3,(H2,7,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Sweden - CoRMS: Slovenia Azimsulfuron (Corrigendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron 26Mar2010 2010 doi:10.2903/j.efsa.2010.1554
+Azimsulfuron 601-676-5 120162-55-2 single chemical entity Component is a metabolite of the substance 1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide 1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide Not in list C6H9N7O2S Cn1nc(nn1)c2cnn(C)c2S(N)(=O)=O InChI=1/C6H9N7O2S/c1-12-6(16(7,14)15)4(3-8-12)5-9-11-13(2)10-5/h3H,1-2H3,(H2,7,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Slovenia Azimsulfuron (Corrigendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron 26Mar2010 2010 doi:10.2903/j.efsa.2010.1554
+Azimsulfuron 601-676-5 120162-55-2 single chemical entity Component is a metabolite of the substance 1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide 1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide Not in list C6H9N7O2S Cn1nc(nn1)c2cnn(C)c2S(N)(=O)=O InChI=1/C6H9N7O2S/c1-12-6(16(7,14)15)4(3-8-12)5-9-11-13(2)10-5/h3H,1-2H3,(H2,7,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Slovenia Azimsulfuron (Corrigendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron 26Mar2010 2010 doi:10.2903/j.efsa.2010.1554
+Azimsulfuron 601-676-5 120162-55-2 single chemical entity Component is a metabolite of the substance 1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide 1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide Not in list C6H9N7O2S Cn1nc(nn1)c2cnn(C)c2S(N)(=O)=O InChI=1/C6H9N7O2S/c1-12-6(16(7,14)15)4(3-8-12)5-9-11-13(2)10-5/h3H,1-2H3,(H2,7,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Sweden - CoRMS: Slovenia Azimsulfuron (Corrigendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron 26Mar2010 2010 doi:10.2903/j.efsa.2010.1554
+Azimsulfuron 601-676-5 120162-55-2 single chemical entity Component is a metabolite of the substance 1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide 1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide Not in list C6H9N7O2S Cn1nc(nn1)c2cnn(C)c2S(N)(=O)=O InChI=1/C6H9N7O2S/c1-12-6(16(7,14)15)4(3-8-12)5-9-11-13(2)10-5/h3H,1-2H3,(H2,7,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Slovenia Azimsulfuron (Corrigendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron 26Mar2010 2010 doi:10.2903/j.efsa.2010.1554
+Azimsulfuron 601-676-5 120162-55-2 single chemical entity Component is a metabolite of the substance 1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide 1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide Not in list C6H9N7O2S Cn1nc(nn1)c2cnn(C)c2S(N)(=O)=O InChI=1/C6H9N7O2S/c1-12-6(16(7,14)15)4(3-8-12)5-9-11-13(2)10-5/h3H,1-2H3,(H2,7,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Slovenia Azimsulfuron (Corrigendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron 26Mar2010 2010 doi:10.2903/j.efsa.2010.1554
+Azimsulfuron 601-676-5 120162-55-2 single chemical entity Component is a metabolite of the substance 1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide 1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide Not in list C6H9N7O2S Cn1nc(nn1)c2cnn(C)c2S(N)(=O)=O InChI=1/C6H9N7O2S/c1-12-6(16(7,14)15)4(3-8-12)5-9-11-13(2)10-5/h3H,1-2H3,(H2,7,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Slovenia Azimsulfuron (Corrigendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron 26Mar2010 2010 doi:10.2903/j.efsa.2010.1554
+Azimsulfuron 601-676-5 120162-55-2 single chemical entity Component is a metabolite of the substance 1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide 1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide Not in list C6H9N7O2S Cn1nc(nn1)c2cnn(C)c2S(N)(=O)=O InChI=1/C6H9N7O2S/c1-12-6(16(7,14)15)4(3-8-12)5-9-11-13(2)10-5/h3H,1-2H3,(H2,7,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes with Negative RMS: Sweden - CoRMS: Slovenia Azimsulfuron (Corrigendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron 26Mar2010 2010 doi:10.2903/j.efsa.2010.1554
+Azoxystrobin 131860-33-8 single chemical entity Component is identical to the substance Azoxystrobin 131860-33-8 methyl (2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyacrylate Azoxystrobin C22H17N3O5 N#CC1=CC=CC=C1OC2=NC=NC(OC3=CC=CC=C3/C(C(OC)=O)=C\OC)=C2 InChI=1S/C22H17N3O5/c1-27-13-17(22(26)28-2)16-8-4-6-10-19(16)30-21-11-20(24-14-25-21)29-18-9-5-3-7-15(18)12-23/h3-11,13-14H,1-2H3/b17-13+ organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Positive RMS: The United Kingdom Azoxystrobin 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin 15Apr2010 2010 doi:10.2903/j.efsa.2010.1542
+Azoxystrobin 131860-33-8 single chemical entity Component is identical to the substance Azoxystrobin 131860-33-8 methyl (2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyacrylate Azoxystrobin C22H17N3O5 N#CC1=CC=CC=C1OC2=NC=NC(OC3=CC=CC=C3/C(C(OC)=O)=C\OC)=C2 InChI=1S/C22H17N3O5/c1-27-13-17(22(26)28-2)16-8-4-6-10-19(16)30-21-11-20(24-14-25-21)29-18-9-5-3-7-15(18)12-23/h3-11,13-14H,1-2H3/b17-13+ organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Positive RMS: The United Kingdom Azoxystrobin 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin 15Apr2010 2010 doi:10.2903/j.efsa.2010.1542
+Azoxystrobin 131860-33-8 single chemical entity Component is identical to the substance Azoxystrobin 131860-33-8 methyl (2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyacrylate Azoxystrobin C22H17N3O5 N#CC1=CC=CC=C1OC2=NC=NC(OC3=CC=CC=C3/C(C(OC)=O)=C\OC)=C2 InChI=1S/C22H17N3O5/c1-27-13-17(22(26)28-2)16-8-4-6-10-19(16)30-21-11-20(24-14-25-21)29-18-9-5-3-7-15(18)12-23/h3-11,13-14H,1-2H3/b17-13+ organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) C57BL 10 Male/Female oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity$indirect evidence-systemic toxicity RMS: The United Kingdom Azoxystrobin 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin 15Apr2010 2010 doi:10.2903/j.efsa.2010.1542
+Azoxystrobin 131860-33-8 single chemical entity Component is identical to the substance Azoxystrobin 131860-33-8 methyl (2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyacrylate Azoxystrobin C22H17N3O5 N#CC1=CC=CC=C1OC2=NC=NC(OC3=CC=CC=C3/C(C(OC)=O)=C\OC)=C2 InChI=1S/C22H17N3O5/c1-27-13-17(22(26)28-2)16-8-4-6-10-19(16)30-21-11-20(24-14-25-21)29-18-9-5-3-7-15(18)12-23/h3-11,13-14H,1-2H3/b17-13+ organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) C57BL 10 Male/Female oral: unspecified 48.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity$indirect evidence-systemic toxicity RMS: The United Kingdom Azoxystrobin 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin 15Apr2010 2010 doi:10.2903/j.efsa.2010.1542
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is identical to the substance Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation yeast cytogenetic assay in vitro Equivalent or similar to OECD Guideline 480 (Genetic Toxicology: Saccharomyces cerevisiae, Gene Mutation Assay) Yes Acceptable Saccharomyces cerevisiae (as organism) D4 Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl 2000 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is identical to the substance Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation yeast cytogenetic assay in vitro Equivalent or similar to OECD Guideline 480 (Genetic Toxicology: Saccharomyces cerevisiae, Gene Mutation Assay) Yes Acceptable Saccharomyces cerevisiae (as organism) D4 Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl 2000 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is identical to the substance Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation yeast cytogenetic assay in vitro Equivalent or similar to OECD Guideline 480 (Genetic Toxicology: Saccharomyces cerevisiae, Gene Mutation Assay) Yes Acceptable Schizosaccharomyces pombe (as organism) Not reported yes with Negative RMS: Portugal Benalaxyl 2000 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is identical to the substance Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation yeast cytogenetic assay in vitro Equivalent or similar to OECD Guideline 480 (Genetic Toxicology: Saccharomyces cerevisiae, Gene Mutation Assay) Yes Acceptable Schizosaccharomyces pombe (as organism) Not reported Not reported yes without Negative RMS: Portugal Benalaxyl 2000 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is identical to the substance Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl 2000 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is identical to the substance Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl 2000 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is identical to the substance Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl 2000 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is identical to the substance Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl 2000 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is identical to the substance Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl 2000 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is identical to the substance Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Hamster (as animal) Not reported 4 Male/Female oral: unspecified 6.0000000000 h yes not applicable Negative RMS: Portugal Benalaxyl 2000 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is identical to the substance Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable Rat (as animal) Not reported 10 Male/Female intraperitoneal 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Portugal Benalaxyl (Addendum 8) 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is identical to the substance Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable Rat (as animal) Not reported 10 Male/Female intraperitoneal 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Portugal Benalaxyl (Addendum 8) 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is identical to the substance Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: Portugal Benalaxyl (Addendum 8) 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is identical to the substance Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: Portugal Benalaxyl (Addendum 8) 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is a metabolite of the substance Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate 3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid Not in list C15H19NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: Portugal Benalaxyl (Addendum 8) 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is a metabolite of the substance Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate 3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid Not in list C15H19NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes without Positive RMS: Portugal Benalaxyl (Addendum 8) 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate 3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid Not in list C15H19NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes without Positive RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate 3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid Not in list C15H19NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate 3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid Not in list C15H19NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate 3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid Not in list C15H19NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Positive RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is a metabolite of the substance Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate 3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid Not in list C15H19NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Positive RMS: Portugal Benalaxyl (Addendum 8) 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is a metabolite of the substance Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate 3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid Not in list C15H19NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl (Addendum 8) 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is a metabolite of the substance Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate 3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid Not in list C15H19NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Not reported 12 Male/Female intraperitoneal 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Portugal Benalaxyl (Addendum 8) 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is a metabolite of the substance Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate 3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid Not in list C15H19NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Not reported 10 Male/Female intraperitoneal 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Portugal Benalaxyl (Addendum 8) 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate 3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid Not in list C15H19NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Not reported 10 Male/Female intraperitoneal 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate 3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid Not in list C15H19NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Not reported 12 Male/Female intraperitoneal 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance N-(malonyl)-N-(2,6-xylyl)-DL-alanine N-(carboxyacetyl)-N-(2,6-dimethylphenyl)alanine Not in list C14H17NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)O InChI=1S/C14H17NO5/c1-8-5-4-6-9(2)13(8)15(10(3)14(19)20)11(16)7-12(17)18/h4-6,10H,7H2,1-3H3,(H,17,18)(H,19,20) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance N-(malonyl)-N-(2,6-xylyl)-DL-alanine N-(carboxyacetyl)-N-(2,6-dimethylphenyl)alanine Not in list C14H17NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)O InChI=1S/C14H17NO5/c1-8-5-4-6-9(2)13(8)15(10(3)14(19)20)11(16)7-12(17)18/h4-6,10H,7H2,1-3H3,(H,17,18)(H,19,20) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is a metabolite of the substance N-(malonyl)-N-(2,6-xylyl)-DL-alanine N-(carboxyacetyl)-N-(2,6-dimethylphenyl)alanine Not in list C14H17NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)O InChI=1S/C14H17NO5/c1-8-5-4-6-9(2)13(8)15(10(3)14(19)20)11(16)7-12(17)18/h4-6,10H,7H2,1-3H3,(H,17,18)(H,19,20) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: Portugal Benalaxyl (Addendum 8) 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is a metabolite of the substance N-(malonyl)-N-(2,6-xylyl)-DL-alanine N-(carboxyacetyl)-N-(2,6-dimethylphenyl)alanine Not in list C14H17NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)O InChI=1S/C14H17NO5/c1-8-5-4-6-9(2)13(8)15(10(3)14(19)20)11(16)7-12(17)18/h4-6,10H,7H2,1-3H3,(H,17,18)(H,19,20) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: Portugal Benalaxyl (Addendum 8) 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benfluralin 217-465-2 1861-40-1 single chemical entity Component is identical to the substance Benfluralin 217-465-2 1861-40-1 N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline Benfluralin C13H16F3N3O4 CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Negative no information RMS: Belgium Benfluralin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin 28Jul2008 2008 doi:10.2903/j.efsa.2008.127r
+Benfluralin 217-465-2 1861-40-1 single chemical entity Component is identical to the substance Benfluralin 217-465-2 1861-40-1 N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline Benfluralin C13H16F3N3O4 CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative no information RMS: Belgium Benfluralin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin 28Jul2008 2008 doi:10.2903/j.efsa.2008.127r
+Benfluralin 217-465-2 1861-40-1 single chemical entity Component is identical to the substance Benfluralin 217-465-2 1861-40-1 N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline Benfluralin C13H16F3N3O4 CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: Belgium Benfluralin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin 28Jul2008 2008 doi:10.2903/j.efsa.2008.127r
+Benfluralin 217-465-2 1861-40-1 single chemical entity Component is identical to the substance Benfluralin 217-465-2 1861-40-1 N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline Benfluralin C13H16F3N3O4 CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: Belgium Benfluralin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin 28Jul2008 2008 doi:10.2903/j.efsa.2008.127r
+Benfluralin 217-465-2 1861-40-1 single chemical entity Component is identical to the substance Benfluralin 217-465-2 1861-40-1 N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline Benfluralin C13H16F3N3O4 CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Belgium Benfluralin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin 28Jul2008 2008 doi:10.2903/j.efsa.2008.127r
+Benfluralin 217-465-2 1861-40-1 single chemical entity Component is identical to the substance Benfluralin 217-465-2 1861-40-1 N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline Benfluralin C13H16F3N3O4 CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vivo No guideline available Not reported Not applicable Acceptable Hamster (as animal) Not reported 3 No data oral: gavage 21.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Belgium Benfluralin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin 28Jul2008 2008 doi:10.2903/j.efsa.2008.127r
+Benfluralin 217-465-2 1861-40-1 single chemical entity Component is identical to the substance Benfluralin 217-465-2 1861-40-1 N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline Benfluralin C13H16F3N3O4 CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 12 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect-toxicokinetic investigations RMS: Belgium Benfluralin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin 28Jul2008 2008 doi:10.2903/j.efsa.2008.127r
+Benfluralin 217-465-2 1861-40-1 single chemical entity Component is identical to the substance Benfluralin 217-465-2 1861-40-1 N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline Benfluralin C13H16F3N3O4 CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 12 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect-toxicokinetic investigations RMS: Belgium Benfluralin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin 28Jul2008 2008 doi:10.2903/j.efsa.2008.127r
+Benfuracarb 82560-54-1 single chemical entity Component is identical to the substance Benfuracarb 82560-54-1 ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate Benfuracarb C20H30N2O5S CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 8 Male/Female oral: gavage 6.0000000000 h no data not applicable Negative indirect-toxicokinetic investigations RMS: Belgium Benfuracarb 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is identical to the substance Benfuracarb 82560-54-1 ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate Benfuracarb C20H30N2O5S CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3 organic compound PubChem canonical SMILES PubChem InChI genome mutation Drosophila SLRL test in vivo Equivalent or similar to OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster) Yes Acceptable Drosophila melanogaster (as animal) Not reported 5 Male oral: feed 3.0000000000 D yes not applicable Negative RMS: Belgium Benfuracarb 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+1-Naphthylacetic acid 201-705-8 86-87-3 single chemical entity Component is identical to the substance 1-Naphthylacetic acid 201-705-8 86-87-3 1-2-naphthalen-1-ylacetic acid 1-naphthylacetic acid C12H10O2 OC(=O)Cc1cccc2ccccc12 InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14) organic compound Other Other genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro According to OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay) No Acceptable Saccharomyces cerevisiae (as organism) D7 Not reported no data without Negative RMS: France Naphtaleneacetic acid 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid 23Feb2011 2011 doi:10.2903/j.efsa.2011.2019
+1-Naphthylacetic acid 201-705-8 86-87-3 single chemical entity Component is identical to the substance 1-Naphthylacetic acid 201-705-8 86-87-3 1-2-naphthalen-1-ylacetic acid 1-naphthylacetic acid C12H10O2 OC(=O)Cc1cccc2ccccc12 InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14) organic compound Other Other gene mutation yeast cytogenetic assay in vitro According to OECD Guideline 480 (Genetic Toxicology: Saccharomyces cerevisiae, Gene Mutation Assay) No Acceptable Saccharomyces cerevisiae (as organism) D7 Not reported no data without Negative RMS: France Naphtaleneacetic acid 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid 23Feb2011 2011 doi:10.2903/j.efsa.2011.2019
+1-Naphthylacetic acid 201-705-8 86-87-3 single chemical entity Component is identical to the substance 1-Naphthylacetic acid 201-705-8 86-87-3 1-2-naphthalen-1-ylacetic acid 1-naphthylacetic acid C12H10O2 OC(=O)Cc1cccc2ccccc12 InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14) organic compound Other Other gene mutation yeast cytogenetic assay in vitro According to OECD Guideline 480 (Genetic Toxicology: Saccharomyces cerevisiae, Gene Mutation Assay) No Acceptable Saccharomyces cerevisiae (as organism) D7 Not reported no data without Negative RMS: France Naphtaleneacetic acid 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid 23Feb2011 2011 doi:10.2903/j.efsa.2011.2019
+2,4-D 202-361-1 94-75-7 single chemical entity Component is identical to the substance 2,4-D 202-361-1 94-75-7 (2,4-dichlorophenoxy)acetic acid 2,4-D C8H6Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCC(=O)O InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) Not reported Not reported no data no data Negative RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-D 202-361-1 94-75-7 single chemical entity Component is identical to the substance 2,4-D 202-361-1 94-75-7 (2,4-dichlorophenoxy)acetic acid 2,4-D C8H6Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCC(=O)O InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) Not reported Not reported no data no data Negative RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-D 202-361-1 94-75-7 single chemical entity Component is identical to the substance 2,4-D 202-361-1 94-75-7 (2,4-dichlorophenoxy)acetic acid 2,4-D C8H6Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCC(=O)O InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) Not reported Not reported no data no data Negative RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-D 202-361-1 94-75-7 single chemical entity Component is identical to the substance 2,4-D 202-361-1 94-75-7 (2,4-dichlorophenoxy)acetic acid 2,4-D C8H6Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCC(=O)O InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-D 202-361-1 94-75-7 single chemical entity Component is identical to the substance 2,4-D 202-361-1 94-75-7 (2,4-dichlorophenoxy)acetic acid 2,4-D C8H6Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCC(=O)O InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Positive large colonies RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-D 202-361-1 94-75-7 single chemical entity Component is identical to the substance 2,4-D 202-361-1 94-75-7 (2,4-dichlorophenoxy)acetic acid 2,4-D C8H6Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCC(=O)O InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Positive small colonies RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-D 202-361-1 94-75-7 single chemical entity Component is identical to the substance 2,4-D 202-361-1 94-75-7 (2,4-dichlorophenoxy)acetic acid 2,4-D C8H6Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCC(=O)O InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-D 202-361-1 94-75-7 single chemical entity Component is identical to the substance 2,4-D 202-361-1 94-75-7 (2,4-dichlorophenoxy)acetic acid 2,4-D C8H6Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCC(=O)O InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Not reported 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-D 202-361-1 94-75-7 single chemical entity Component is identical to the substance 2,4-D 202-361-1 94-75-7 (2,4-dichlorophenoxy)acetic acid 2,4-D C8H6Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCC(=O)O InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Not reported 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-D 202-361-1 94-75-7 single chemical entity Component is identical to the substance 2,4-D 202-361-1 94-75-7 (2,4-dichlorophenoxy)acetic acid 2,4-D C8H6Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCC(=O)O InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Not reported 10 Male/Female oral: gavage 72.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-D 202-361-1 94-75-7 single chemical entity Component is identical to the substance 2,4-D 202-361-1 94-75-7 (2,4-dichlorophenoxy)acetic acid 2,4-D C8H6Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCC(=O)O InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI genome mutation Drosophila SLRL test in vivo Equivalent or similar to OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster) Yes Acceptable Drosophila melanogaster (as animal) Not reported Male oral: feed 2.0000000000 week yes not applicable Positive RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-D 202-361-1 94-75-7 single chemical entity Component is identical to the substance 2,4-D 202-361-1 94-75-7 (2,4-dichlorophenoxy)acetic acid 2,4-D C8H6Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCC(=O)O InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration other in vivo No guideline available Not reported Not applicable Acceptable Drosophila melanogaster (as animal) Not reported Male/Female oral: feed yes not applicable Negative RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-D 202-361-1 94-75-7 single chemical entity Component is a metabolite of the substance 2,4-dichlorophenol 204-429-6 120-83-2 2,4-dichlorophenol Not in list C6H4Cl2O C1=CC(=C(C=C1Cl)Cl)O InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Positive no information RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-D 202-361-1 94-75-7 single chemical entity Component is a metabolite of the substance 2,4-dichlorophenol 204-429-6 120-83-2 2,4-dichlorophenol Not in list C6H4Cl2O C1=CC(=C(C=C1Cl)Cl)O InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) Yes Acceptable Hamster (as animal) CHO Not reported yes with Positive RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-D 202-361-1 94-75-7 single chemical entity Component is a metabolite of the substance 2,4-dichlorophenol 204-429-6 120-83-2 2,4-dichlorophenol Not in list C6H4Cl2O C1=CC(=C(C=C1Cl)Cl)O InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-D 202-361-1 94-75-7 single chemical entity Component is a metabolite of the substance 2,4-dichlorophenol 204-429-6 120-83-2 2,4-dichlorophenol Not in list C6H4Cl2O C1=CC(=C(C=C1Cl)Cl)O InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-D 202-361-1 94-75-7 single chemical entity Component is a metabolite of the substance 2,4-dichlorophenol 204-429-6 120-83-2 2,4-dichlorophenol Not in list C6H4Cl2O C1=CC(=C(C=C1Cl)Cl)O InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-D 202-361-1 94-75-7 single chemical entity Component is a metabolite of the substance 2,4-dichlorophenol 204-429-6 120-83-2 2,4-dichlorophenol Not in list C6H4Cl2O C1=CC(=C(C=C1Cl)Cl)O InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) Yes Acceptable Hamster (as animal) CHO Not reported yes without Positive RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-D 202-361-1 94-75-7 single chemical entity Component is a metabolite of the substance 2,4-dichlorophenol 204-429-6 120-83-2 2,4-dichlorophenol Not in list C6H4Cl2O C1=CC(=C(C=C1Cl)Cl)O InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-D 202-361-1 94-75-7 single chemical entity Component is a metabolite of the substance 2,4-dichlorophenol 204-429-6 120-83-2 2,4-dichlorophenol Not in list C6H4Cl2O C1=CC(=C(C=C1Cl)Cl)O InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-D 202-361-1 94-75-7 single chemical entity Component is a metabolite of the substance 2,4-dichlorophenol 204-429-6 120-83-2 2,4-dichlorophenol Not in list C6H4Cl2O C1=CC(=C(C=C1Cl)Cl)O InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-D 202-361-1 94-75-7 single chemical entity Component is a metabolite of the substance 2,4-dichlorophenol 204-429-6 120-83-2 2,4-dichlorophenol Not in list C6H4Cl2O C1=CC(=C(C=C1Cl)Cl)O InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Ambiguous RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-D 202-361-1 94-75-7 single chemical entity Component is a metabolite of the substance 4-chlorophenol 203-402-6 106-48-9 4-chlorophenol Not in list C6H5ClO C1=CC(=CC=C1O)Cl InChI=1S/C6H5ClO/c7-5-1-3-6(8)4-2-5/h1-4,8H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-D 202-361-1 94-75-7 single chemical entity Component is a metabolite of the substance 2,4-dichlorophenol 204-429-6 120-83-2 2,4-dichlorophenol Not in list C6H4Cl2O C1=CC(=C(C=C1Cl)Cl)O InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-D 202-361-1 94-75-7 single chemical entity Component is a metabolite of the substance 2,4-dichlorophenol 204-429-6 120-83-2 2,4-dichlorophenol Not in list C6H4Cl2O C1=CC(=C(C=C1Cl)Cl)O InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is identical to the substance 2,4-DB 202-366-9 94-82-6 4-(2,4-dichlorophenoxy)butanoic acid 2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB) C10H10Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is identical to the substance 2,4-DB 202-366-9 94-82-6 4-(2,4-dichlorophenoxy)butanoic acid 2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB) C10H10Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is identical to the substance 2,4-DB 202-366-9 94-82-6 4-(2,4-dichlorophenoxy)butanoic acid 2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB) C10H10Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is identical to the substance 2,4-DB 202-366-9 94-82-6 4-(2,4-dichlorophenoxy)butanoic acid 2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB) C10H10Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is identical to the substance 2,4-DB 202-366-9 94-82-6 4-(2,4-dichlorophenoxy)butanoic acid 2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB) C10H10Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is identical to the substance 2,4-DB 202-366-9 94-82-6 4-(2,4-dichlorophenoxy)butanoic acid 2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB) C10H10Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is identical to the substance 2,4-DB 202-366-9 94-82-6 4-(2,4-dichlorophenoxy)butanoic acid 2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB) C10H10Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is identical to the substance 2,4-DB 202-366-9 94-82-6 4-(2,4-dichlorophenoxy)butanoic acid 2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB) C10H10Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is identical to the substance 2,4-DB 202-366-9 94-82-6 4-(2,4-dichlorophenoxy)butanoic acid 2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB) C10H10Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is identical to the substance 2,4-DB 202-366-9 94-82-6 4-(2,4-dichlorophenoxy)butanoic acid 2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB) C10H10Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is identical to the substance 2,4-DB 202-366-9 94-82-6 4-(2,4-dichlorophenoxy)butanoic acid 2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB) C10H10Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is identical to the substance 2,4-DB 202-366-9 94-82-6 4-(2,4-dichlorophenoxy)butanoic acid 2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB) C10H10Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is identical to the substance 2,4-DB 202-366-9 94-82-6 4-(2,4-dichlorophenoxy)butanoic acid 2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB) C10H10Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is identical to the substance 2,4-DB 202-366-9 94-82-6 4-(2,4-dichlorophenoxy)butanoic acid 2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB) C10H10Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is identical to the substance 2,4-DB 202-366-9 94-82-6 4-(2,4-dichlorophenoxy)butanoic acid 2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB) C10H10Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is identical to the substance 2,4-DB 202-366-9 94-82-6 4-(2,4-dichlorophenoxy)butanoic acid 2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB) C10H10Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is identical to the substance 2,4-DB 202-366-9 94-82-6 4-(2,4-dichlorophenoxy)butanoic acid 2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB) C10H10Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is identical to the substance 2,4-DB 202-366-9 94-82-6 4-(2,4-dichlorophenoxy)butanoic acid 2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB) C10H10Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is identical to the substance 2,4-DB 202-366-9 94-82-6 4-(2,4-dichlorophenoxy)butanoic acid 2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB) C10H10Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is identical to the substance 2,4-DB 202-366-9 94-82-6 4-(2,4-dichlorophenoxy)butanoic acid 2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB) C10H10Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is part of a mixture or forumlation Butyrac 200 202-366-9 94-82-6 4-(2,4-dichlorophenoxy)butanoic acid 2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB) C10H10Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is part of a mixture or forumlation Butyrac 200 202-366-9 94-82-6 4-(2,4-dichlorophenoxy)butanoic acid 2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB) C10H10Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Positive RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is identical to the substance 2,4-DB 202-366-9 94-82-6 4-(2,4-dichlorophenoxy)butanoic acid 2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB) C10H10Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is identical to the substance 2,4-DB 202-366-9 94-82-6 4-(2,4-dichlorophenoxy)butanoic acid 2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB) C10H10Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is identical to the substance 2,4-DB 202-366-9 94-82-6 4-(2,4-dichlorophenoxy)butanoic acid 2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB) C10H10Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is identical to the substance 2,4-DB 202-366-9 94-82-6 4-(2,4-dichlorophenoxy)butanoic acid 2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB) C10H10Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes without Positive RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is part of a mixture or forumlation Butyrac 200 202-366-9 94-82-6 4-(2,4-dichlorophenoxy)butanoic acid 2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB) C10H10Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is part of a mixture or forumlation Butyrac 200 202-366-9 94-82-6 4-(2,4-dichlorophenoxy)butanoic acid 2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB) C10H10Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is identical to the substance 2,4-DB 202-366-9 94-82-6 4-(2,4-dichlorophenoxy)butanoic acid 2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB) C10H10Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Rat (as animal) hepatocytes Not reported yes without Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is part of a mixture or forumlation Butyrac 200 202-366-9 94-82-6 4-(2,4-dichlorophenoxy)butanoic acid 2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB) C10H10Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Rat (as animal) hepatocytes Not reported yes without Positive RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is identical to the substance 2,4-DB 202-366-9 94-82-6 4-(2,4-dichlorophenoxy)butanoic acid 2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB) C10H10Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity$indirect evidence-systemic toxicity RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is identical to the substance 2,4-DB 202-366-9 94-82-6 4-(2,4-dichlorophenoxy)butanoic acid 2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB) C10H10Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity$indirect evidence-systemic toxicity RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+Bensulfuron-methyl 401-340-6 83055-99-6 single chemical entity Component is identical to the substance Bensulfuron-methyl 401-340-6 83055-99-6 Methyl 2-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoylmethyl]benzoate Bensulfuron-Methyl C16H18N4O7S COC1=CC(=NC(=N1)NC(=O)NS(=O)(=O)CC2=CC=CC=C2C(=O)OC)OC InChI=1S/C16H18N4O7S/c1-25-12-8-13(26-2)18-15(17-12)19-16(22)20-28(23,24)9-10-6-4-5-7-11(10)14(21)27-3/h4-8H,9H2,1-3H3,(H2,17,18,19,20,22) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Italy Bensulfuron Methyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.178r
+Bensulfuron-methyl 401-340-6 83055-99-6 single chemical entity Component is a metabolite of the substance 2-Amino-4,6-dimethoxypyrimidine 252-969-6 36315-01-2 4,6-Dimethoxypyrimidin-2-amine Not in list C6H9N3O2 COC1=CC(=NC(=N1)N)OC InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Italy Bensulfuron Methyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.178r
+Bensulfuron-methyl 401-340-6 83055-99-6 single chemical entity Component is a metabolite of the substance 2-Amino-4,6-dimethoxypyrimidine 252-969-6 36315-01-2 4,6-Dimethoxypyrimidin-2-amine Not in list C6H9N3O2 COC1=CC(=NC(=N1)N)OC InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Italy Bensulfuron Methyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.178r
+Bensulfuron-methyl 401-340-6 83055-99-6 single chemical entity Component is a metabolite of the substance 2-Amino-4,6-dimethoxypyrimidine 252-969-6 36315-01-2 4,6-Dimethoxypyrimidin-2-amine Not in list C6H9N3O2 COC1=CC(=NC(=N1)N)OC InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Italy Bensulfuron Methyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.178r
+Bensulfuron-methyl 401-340-6 83055-99-6 single chemical entity Component is a metabolite of the substance 2-Amino-4,6-dimethoxypyrimidine 252-969-6 36315-01-2 4,6-Dimethoxypyrimidin-2-amine Not in list C6H9N3O2 COC1=CC(=NC(=N1)N)OC InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle with Negative RMS: Italy Bensulfuron Methyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.178r
+Bensulfuron-methyl 401-340-6 83055-99-6 single chemical entity Component is a metabolite of the substance 2-Amino-4,6-dimethoxypyrimidine 252-969-6 36315-01-2 4,6-Dimethoxypyrimidin-2-amine Not in list C6H9N3O2 COC1=CC(=NC(=N1)N)OC InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Italy Bensulfuron Methyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.178r
+Bensulfuron-methyl 401-340-6 83055-99-6 single chemical entity Component is a metabolite of the substance 2-Amino-4,6-dimethoxypyrimidine 252-969-6 36315-01-2 4,6-Dimethoxypyrimidin-2-amine Not in list C6H9N3O2 COC1=CC(=NC(=N1)N)OC InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle with Negative RMS: Italy Bensulfuron Methyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.178r
+Bensulfuron-methyl 401-340-6 83055-99-6 single chemical entity Component is a metabolite of the substance 2-Amino-4,6-dimethoxypyrimidine 252-969-6 36315-01-2 4,6-Dimethoxypyrimidin-2-amine Not in list C6H9N3O2 COC1=CC(=NC(=N1)N)OC InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Italy Bensulfuron Methyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.178r
+Bensulfuron-methyl 401-340-6 83055-99-6 single chemical entity Component is a metabolite of the substance 2-Amino-4,6-dimethoxypyrimidine 252-969-6 36315-01-2 4,6-Dimethoxypyrimidin-2-amine Not in list C6H9N3O2 COC1=CC(=NC(=N1)N)OC InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle with Negative RMS: Italy Bensulfuron Methyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.178r
+Bensulfuron-methyl 401-340-6 83055-99-6 single chemical entity Component is a metabolite of the substance 2-Amino-4,6-dimethoxypyrimidine 252-969-6 36315-01-2 4,6-Dimethoxypyrimidin-2-amine Not in list C6H9N3O2 COC1=CC(=NC(=N1)N)OC InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Italy Bensulfuron Methyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.178r
+Bensulfuron-methyl 401-340-6 83055-99-6 single chemical entity Component is a metabolite of the substance 2-Amino-4,6-dimethoxypyrimidine 252-969-6 36315-01-2 4,6-Dimethoxypyrimidin-2-amine Not in list C6H9N3O2 COC1=CC(=NC(=N1)N)OC InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle with Negative RMS: Italy Bensulfuron Methyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.178r
+Bensulfuron-methyl 401-340-6 83055-99-6 single chemical entity Component is a metabolite of the substance 1H-2, 3-benzothiazin-4(3H)-one 2,2-dioxide 244-577-9 21784-53-2 2,2-dioxo-1H-2$l^{6},3-benzothiazin-4-one Not in list C8H7NO3S C1C2=CC=CC=C2C(=O)NS1(=O)=O InChI=1S/C8H7NO3S/c10-8-7-4-2-1-3-6(7)5-13(11,12)9-8/h1-4H,5H2,(H,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Italy Bensulfuron Methyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.178r
+Bensulfuron-methyl 401-340-6 83055-99-6 single chemical entity Component is a metabolite of the substance 1H-2, 3-benzothiazin-4(3H)-one 2,2-dioxide 244-577-9 21784-53-2 2,2-dioxo-1H-2$l^{6},3-benzothiazin-4-one Not in list C8H7NO3S C1C2=CC=CC=C2C(=O)NS1(=O)=O InChI=1S/C8H7NO3S/c10-8-7-4-2-1-3-6(7)5-13(11,12)9-8/h1-4H,5H2,(H,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle without Negative RMS: Italy Bensulfuron Methyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.178r
+Bensulfuron-methyl 401-340-6 83055-99-6 single chemical entity Component is a metabolite of the substance 1H-2, 3-benzothiazin-4(3H)-one 2,2-dioxide 244-577-9 21784-53-2 2,2-dioxo-1H-2$l^{6},3-benzothiazin-4-one Not in list C8H7NO3S C1C2=CC=CC=C2C(=O)NS1(=O)=O InChI=1S/C8H7NO3S/c10-8-7-4-2-1-3-6(7)5-13(11,12)9-8/h1-4H,5H2,(H,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Italy Bensulfuron Methyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.178r
+Bensulfuron-methyl 401-340-6 83055-99-6 single chemical entity Component is a metabolite of the substance 1H-2, 3-benzothiazin-4(3H)-one 2,2-dioxide 244-577-9 21784-53-2 2,2-dioxo-1H-2$l^{6},3-benzothiazin-4-one Not in list C8H7NO3S C1C2=CC=CC=C2C(=O)NS1(=O)=O InChI=1S/C8H7NO3S/c10-8-7-4-2-1-3-6(7)5-13(11,12)9-8/h1-4H,5H2,(H,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Italy Bensulfuron Methyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.178r
+Bensulfuron-methyl 401-340-6 83055-99-6 single chemical entity Component is a metabolite of the substance 1H-2, 3-benzothiazin-4(3H)-one 2,2-dioxide 244-577-9 21784-53-2 2,2-dioxo-1H-2$l^{6},3-benzothiazin-4-one Not in list C8H7NO3S C1C2=CC=CC=C2C(=O)NS1(=O)=O InChI=1S/C8H7NO3S/c10-8-7-4-2-1-3-6(7)5-13(11,12)9-8/h1-4H,5H2,(H,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle with Negative RMS: Italy Bensulfuron Methyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.178r
+Bensulfuron-methyl 401-340-6 83055-99-6 single chemical entity Component is a metabolite of the substance 1H-2, 3-benzothiazin-4(3H)-one 2,2-dioxide 244-577-9 21784-53-2 2,2-dioxo-1H-2$l^{6},3-benzothiazin-4-one Not in list C8H7NO3S C1C2=CC=CC=C2C(=O)NS1(=O)=O InChI=1S/C8H7NO3S/c10-8-7-4-2-1-3-6(7)5-13(11,12)9-8/h1-4H,5H2,(H,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Italy Bensulfuron Methyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.178r
+Bensulfuron-methyl 401-340-6 83055-99-6 single chemical entity Component is a metabolite of the substance 1H-2, 3-benzothiazin-4(3H)-one 2,2-dioxide 244-577-9 21784-53-2 2,2-dioxo-1H-2$l^{6},3-benzothiazin-4-one Not in list C8H7NO3S C1C2=CC=CC=C2C(=O)NS1(=O)=O InChI=1S/C8H7NO3S/c10-8-7-4-2-1-3-6(7)5-13(11,12)9-8/h1-4H,5H2,(H,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Italy Bensulfuron Methyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.178r
+Bensulfuron-methyl 401-340-6 83055-99-6 single chemical entity Component is a metabolite of the substance 1H-2, 3-benzothiazin-4(3H)-one 2,2-dioxide 244-577-9 21784-53-2 2,2-dioxo-1H-2$l^{6},3-benzothiazin-4-one Not in list C8H7NO3S C1C2=CC=CC=C2C(=O)NS1(=O)=O InChI=1S/C8H7NO3S/c10-8-7-4-2-1-3-6(7)5-13(11,12)9-8/h1-4H,5H2,(H,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Italy Bensulfuron Methyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.178r
+Bensulfuron-methyl 401-340-6 83055-99-6 single chemical entity Component is a metabolite of the substance α-[(4,6-dimethoxypyrimidin-2-ylcarbamoyl)sulfamoyl]-o-toluic acid 2-({[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]sulfamoyl}methyl)benzoic acid Not in list C15H16N4O7S COC1=CC(=NC(=N1)NC(=O)NS(=O)(=O)CC2=CC=CC=C2C(=O)O)OC InChI=1S/C15H16N4O7S/c1-25-11-7-12(26-2)17-14(16-11)18-15(22)19-27(23,24)8-9-5-3-4-6-10(9)13(20)21/h3-7H,8H2,1-2H3,(H,20,21)(H2,16,17,18,19,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Italy Bensulfuron Methyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.178r
+Bensulfuron-methyl 401-340-6 83055-99-6 single chemical entity Component is a metabolite of the substance α-[(4,6-dimethoxypyrimidin-2-ylcarbamoyl)sulfamoyl]-o-toluic acid 2-({[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]sulfamoyl}methyl)benzoic acid Not in list C15H16N4O7S COC1=CC(=NC(=N1)NC(=O)NS(=O)(=O)CC2=CC=CC=C2C(=O)O)OC InChI=1S/C15H16N4O7S/c1-25-11-7-12(26-2)17-14(16-11)18-15(22)19-27(23,24)8-9-5-3-4-6-10(9)13(20)21/h3-7H,8H2,1-2H3,(H,20,21)(H2,16,17,18,19,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Italy Bensulfuron Methyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.178r
+Bensulfuron-methyl 401-340-6 83055-99-6 single chemical entity Component is a metabolite of the substance α-[(4,6-dimethoxypyrimidin-2-ylcarbamoyl)sulfamoyl]-o-toluic acid 2-({[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]sulfamoyl}methyl)benzoic acid Not in list C15H16N4O7S COC1=CC(=NC(=N1)NC(=O)NS(=O)(=O)CC2=CC=CC=C2C(=O)O)OC InChI=1S/C15H16N4O7S/c1-25-11-7-12(26-2)17-14(16-11)18-15(22)19-27(23,24)8-9-5-3-4-6-10(9)13(20)21/h3-7H,8H2,1-2H3,(H,20,21)(H2,16,17,18,19,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Italy Bensulfuron Methyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.178r
+Bensulfuron-methyl 401-340-6 83055-99-6 single chemical entity Component is a metabolite of the substance α-[(4,6-dimethoxypyrimidin-2-ylcarbamoyl)sulfamoyl]-o-toluic acid 2-({[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]sulfamoyl}methyl)benzoic acid Not in list C15H16N4O7S COC1=CC(=NC(=N1)NC(=O)NS(=O)(=O)CC2=CC=CC=C2C(=O)O)OC InChI=1S/C15H16N4O7S/c1-25-11-7-12(26-2)17-14(16-11)18-15(22)19-27(23,24)8-9-5-3-4-6-10(9)13(20)21/h3-7H,8H2,1-2H3,(H,20,21)(H2,16,17,18,19,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Italy Bensulfuron Methyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.178r
+Bensulfuron-methyl 401-340-6 83055-99-6 single chemical entity Component is a metabolite of the substance α-[(4,6-dimethoxypyrimidin-2-ylcarbamoyl)sulfamoyl]-o-toluic acid 2-({[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]sulfamoyl}methyl)benzoic acid Not in list C15H16N4O7S COC1=CC(=NC(=N1)NC(=O)NS(=O)(=O)CC2=CC=CC=C2C(=O)O)OC InChI=1S/C15H16N4O7S/c1-25-11-7-12(26-2)17-14(16-11)18-15(22)19-27(23,24)8-9-5-3-4-6-10(9)13(20)21/h3-7H,8H2,1-2H3,(H,20,21)(H2,16,17,18,19,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Italy Bensulfuron Methyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.178r
+Bensulfuron-methyl 401-340-6 83055-99-6 single chemical entity Component is a metabolite of the substance α-[(4,6-dimethoxypyrimidin-2-ylcarbamoyl)sulfamoyl]-o-toluic acid 2-({[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]sulfamoyl}methyl)benzoic acid Not in list C15H16N4O7S COC1=CC(=NC(=N1)NC(=O)NS(=O)(=O)CC2=CC=CC=C2C(=O)O)OC InChI=1S/C15H16N4O7S/c1-25-11-7-12(26-2)17-14(16-11)18-15(22)19-27(23,24)8-9-5-3-4-6-10(9)13(20)21/h3-7H,8H2,1-2H3,(H,20,21)(H2,16,17,18,19,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle with Negative RMS: Italy Bensulfuron Methyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.178r
+Bensulfuron-methyl 401-340-6 83055-99-6 single chemical entity Component is a metabolite of the substance α-[(4,6-dimethoxypyrimidin-2-ylcarbamoyl)sulfamoyl]-o-toluic acid 2-({[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]sulfamoyl}methyl)benzoic acid Not in list C15H16N4O7S COC1=CC(=NC(=N1)NC(=O)NS(=O)(=O)CC2=CC=CC=C2C(=O)O)OC InChI=1S/C15H16N4O7S/c1-25-11-7-12(26-2)17-14(16-11)18-15(22)19-27(23,24)8-9-5-3-4-6-10(9)13(20)21/h3-7H,8H2,1-2H3,(H,20,21)(H2,16,17,18,19,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle without Negative RMS: Italy Bensulfuron Methyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.178r
+Bensulfuron-methyl 401-340-6 83055-99-6 single chemical entity Component is a metabolite of the substance α-[(4,6-dimethoxypyrimidin-2-ylcarbamoyl)sulfamoyl]-o-toluic acid 2-({[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]sulfamoyl}methyl)benzoic acid Not in list C15H16N4O7S COC1=CC(=NC(=N1)NC(=O)NS(=O)(=O)CC2=CC=CC=C2C(=O)O)OC InChI=1S/C15H16N4O7S/c1-25-11-7-12(26-2)17-14(16-11)18-15(22)19-27(23,24)8-9-5-3-4-6-10(9)13(20)21/h3-7H,8H2,1-2H3,(H,20,21)(H2,16,17,18,19,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Italy Bensulfuron Methyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.178r
+Bensulfuron-methyl 401-340-6 83055-99-6 single chemical entity Component is a metabolite of the substance methyl 2-(sulfamoylmethyl)benzoate 419-010-5 112941-26-1 methyl 2-(sulfamoylmethyl)benzoate Not in list C9H11NO4S COC(=O)C1=CC=CC=C1CS(=O)(=O)N InChI=1S/C9H11NO4S/c1-14-9(11)8-5-3-2-4-7(8)6-15(10,12)13/h2-5H,6H2,1H3,(H2,10,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Italy Bensulfuron Methyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.178r
+Bensulfuron-methyl 401-340-6 83055-99-6 single chemical entity Component is a metabolite of the substance 1H-2, 3-benzothiazin-4(3H)-one 2,2-dioxide 244-577-9 21784-53-2 2,2-dioxo-1H-2$l^{6},3-benzothiazin-4-one Not in list C8H7NO3S C1C2=CC=CC=C2C(=O)NS1(=O)=O InChI=1S/C8H7NO3S/c10-8-7-4-2-1-3-6(7)5-13(11,12)9-8/h1-4H,5H2,(H,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Italy Bensulfuron Methyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.178r
+Bensulfuron-methyl 401-340-6 83055-99-6 single chemical entity Component is a metabolite of the substance 1H-2, 3-benzothiazin-4(3H)-one 2,2-dioxide 244-577-9 21784-53-2 2,2-dioxo-1H-2$l^{6},3-benzothiazin-4-one Not in list C8H7NO3S C1C2=CC=CC=C2C(=O)NS1(=O)=O InChI=1S/C8H7NO3S/c10-8-7-4-2-1-3-6(7)5-13(11,12)9-8/h1-4H,5H2,(H,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle with Negative RMS: Italy Bensulfuron Methyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.178r
+Bensulfuron-methyl 401-340-6 83055-99-6 single chemical entity Component is a metabolite of the substance methyl 2-(sulfamoylmethyl)benzoate 419-010-5 112941-26-1 methyl 2-(sulfamoylmethyl)benzoate Not in list C9H11NO4S COC(=O)C1=CC=CC=C1CS(=O)(=O)N InChI=1S/C9H11NO4S/c1-14-9(11)8-5-3-2-4-7(8)6-15(10,12)13/h2-5H,6H2,1H3,(H2,10,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Italy Bensulfuron Methyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.178r
+Bensulfuron-methyl 401-340-6 83055-99-6 single chemical entity Component is a metabolite of the substance methyl 2-(sulfamoylmethyl)benzoate 419-010-5 112941-26-1 methyl 2-(sulfamoylmethyl)benzoate Not in list C9H11NO4S COC(=O)C1=CC=CC=C1CS(=O)(=O)N InChI=1S/C9H11NO4S/c1-14-9(11)8-5-3-2-4-7(8)6-15(10,12)13/h2-5H,6H2,1H3,(H2,10,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle without Negative RMS: Italy Bensulfuron Methyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.178r
+Bensulfuron-methyl 401-340-6 83055-99-6 single chemical entity Component is a metabolite of the substance methyl 2-(sulfamoylmethyl)benzoate 419-010-5 112941-26-1 methyl 2-(sulfamoylmethyl)benzoate Not in list C9H11NO4S COC(=O)C1=CC=CC=C1CS(=O)(=O)N InChI=1S/C9H11NO4S/c1-14-9(11)8-5-3-2-4-7(8)6-15(10,12)13/h2-5H,6H2,1H3,(H2,10,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Italy Bensulfuron Methyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.178r
+Bensulfuron-methyl 401-340-6 83055-99-6 single chemical entity Component is a metabolite of the substance methyl 2-(sulfamoylmethyl)benzoate 419-010-5 112941-26-1 methyl 2-(sulfamoylmethyl)benzoate Not in list C9H11NO4S COC(=O)C1=CC=CC=C1CS(=O)(=O)N InChI=1S/C9H11NO4S/c1-14-9(11)8-5-3-2-4-7(8)6-15(10,12)13/h2-5H,6H2,1H3,(H2,10,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Italy Bensulfuron Methyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.178r
+Bensulfuron-methyl 401-340-6 83055-99-6 single chemical entity Component is a metabolite of the substance 1H-2, 3-benzothiazin-4(3H)-one 2,2-dioxide 244-577-9 21784-53-2 2,2-dioxo-1H-2$l^{6},3-benzothiazin-4-one Not in list C8H7NO3S C1C2=CC=CC=C2C(=O)NS1(=O)=O InChI=1S/C8H7NO3S/c10-8-7-4-2-1-3-6(7)5-13(11,12)9-8/h1-4H,5H2,(H,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Italy Bensulfuron Methyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.178r
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) Yes Acceptable House mouse (as animal) NMRI 20 Male intraperitoneal 20.0000000000 h yes not applicable Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) Yes Acceptable Rat (as animal) Sprague-Dawley 20 Male oral: feed 13.0000000000 week yes not applicable Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo Equivalent or similar to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) Yes Acceptable House mouse (as animal) B6C3F1 8 Male intraperitoneal 6.0000000000 h yes not applicable Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Negative no information RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vitro No guideline available Not reported Not applicable Acceptable Human (as organism) lymphocytes Not reported yes with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vitro No guideline available Not reported Not applicable Acceptable Human (as organism) lymphocytes Not reported yes without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 8 Male oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Fischer344 8 Male/Female oral: gavage 2.0000000000 h yes not applicable Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Fischer344 8 Male/Female oral: gavage 16.0000000000 h yes not applicable Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation other in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) Balb/c 5 Male oral: gavage 28.0000000000 D yes, concurrent vehicle not applicable Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Bifenox 255-894-7 42576-02-3 single chemical entity Component is identical to the substance Bifenox 255-894-7 42576-02-3 methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate Bifenox C14H9Cl2NO5 [O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3 organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Rat (as animal) hepatocytes Not reported yes without Negative RMS: Belgium Bifenox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox 14Feb2008 2008 doi:10.2903/j.efsa.2008.119r
+Bifenox 255-894-7 42576-02-3 single chemical entity Component is identical to the substance Bifenox 255-894-7 42576-02-3 methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate Bifenox C14H9Cl2NO5 [O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Sprague-Dawley 6 Male oral: gavage 6.0000000000 h yes not applicable Negative RMS: Belgium Bifenox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox 14Feb2008 2008 doi:10.2903/j.efsa.2008.119r
+Bifenthrin 617-373-6 82657-04-3 single chemical entity Component is identical to the substance Bifenthrin 617-373-6 82657-04-3 (2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Bifenthrin C23H22ClF3O2 O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12- organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported no data without Positive RMS: France Bifenthrin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin 19May2011 2011 doi:10.2903/j.efsa.2011.2159
+Bifenthrin 617-373-6 82657-04-3 single chemical entity Component is identical to the substance Bifenthrin 617-373-6 82657-04-3 (2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Bifenthrin C23H22ClF3O2 O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12- organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes without Negative RMS: France Bifenthrin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin 19May2011 2011 doi:10.2903/j.efsa.2011.2159
+Bifenthrin 617-373-6 82657-04-3 single chemical entity Component is identical to the substance Bifenthrin 617-373-6 82657-04-3 (2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Bifenthrin C23H22ClF3O2 O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12- organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Sprague-Dawley 5 Male oral: gavage 6.0000000000 h yes, concurrent vehicle not applicable Negative RMS: France Bifenthrin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin 19May2011 2011 doi:10.2903/j.efsa.2011.2159
+Bifenthrin 617-373-6 82657-04-3 single chemical entity Component is identical to the substance Bifenthrin 617-373-6 82657-04-3 (2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Bifenthrin C23H22ClF3O2 O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12- organic compound Other Other genome mutation Drosophila SLRL test in vivo According to OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster) No Acceptable Drosophila melanogaster (as animal) Not reported 200 Male oral: feed 24.0000000000 h yes not applicable Negative RMS: France Bifenthrin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin 19May2011 2011 doi:10.2903/j.efsa.2011.2159
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is identical to the substance Bitertanol 259-513-5 55179-31-2 1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Bitertanol C20H23N3O2 CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3 InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is identical to the substance Bitertanol 259-513-5 55179-31-2 1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Bitertanol C20H23N3O2 CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3 InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is identical to the substance Bitertanol 259-513-5 55179-31-2 1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Bitertanol C20H23N3O2 CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3 InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is identical to the substance Bitertanol 259-513-5 55179-31-2 1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Bitertanol C20H23N3O2 CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3 InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is identical to the substance Bitertanol 259-513-5 55179-31-2 1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Bitertanol C20H23N3O2 CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3 InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is identical to the substance Bitertanol 259-513-5 55179-31-2 1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Bitertanol C20H23N3O2 CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3 InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is identical to the substance Bitertanol 259-513-5 55179-31-2 1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Bitertanol C20H23N3O2 CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3 InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is identical to the substance Bitertanol 259-513-5 55179-31-2 1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Bitertanol C20H23N3O2 CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3 InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is identical to the substance Bitertanol 259-513-5 55179-31-2 1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Bitertanol C20H23N3O2 CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3 InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3 organic compound Other Other chromosome aberration other in vitro No guideline available Not reported Not applicable Acceptable Sordaria brevicollis (as organism) Not reported Not reported yes without Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is identical to the substance Bitertanol 259-513-5 55179-31-2 1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Bitertanol C20H23N3O2 CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3 InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI Male/Female oral: gavage 6.0000000000 h no data not applicable Negative no evidence RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is identical to the substance Bitertanol 259-513-5 55179-31-2 1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Bitertanol C20H23N3O2 CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3 InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3 organic compound Other Other chromosome aberration dominant lethal assay in vivo According to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) No Acceptable House mouse (as animal) NMRI 50 Male oral: unspecified yes not applicable Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bixafen 581809-46-3 single chemical entity Component is identical to the substance Bixafen 581809-46-3 N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide Bixafen C18H12Cl2F3N3O FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1 InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Bixafen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen 05Nov2012 2012 doi:10.2903/j.efsa.2012.2917
+Bixafen 581809-46-3 single chemical entity Component is identical to the substance Bixafen 581809-46-3 N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide Bixafen C18H12Cl2F3N3O FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1 InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Bixafen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen 05Nov2012 2012 doi:10.2903/j.efsa.2012.2917
+Bixafen 581809-46-3 single chemical entity Component is identical to the substance Bixafen 581809-46-3 N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide Bixafen C18H12Cl2F3N3O FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1 InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Bixafen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen 05Nov2012 2012 doi:10.2903/j.efsa.2012.2917
+Bixafen 581809-46-3 single chemical entity Component is identical to the substance Bixafen 581809-46-3 N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide Bixafen C18H12Cl2F3N3O FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1 InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Bixafen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen 05Nov2012 2012 doi:10.2903/j.efsa.2012.2917
+Bixafen 581809-46-3 single chemical entity Component is identical to the substance Bixafen 581809-46-3 N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide Bixafen C18H12Cl2F3N3O FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1 InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Bixafen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen 05Nov2012 2012 doi:10.2903/j.efsa.2012.2917
+Bixafen 581809-46-3 single chemical entity Component is identical to the substance Bixafen 581809-46-3 N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide Bixafen C18H12Cl2F3N3O FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1 InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Bixafen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen 05Nov2012 2012 doi:10.2903/j.efsa.2012.2917
+Bixafen 581809-46-3 single chemical entity Component is identical to the substance Bixafen 581809-46-3 N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide Bixafen C18H12Cl2F3N3O FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1 InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Bixafen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen 05Nov2012 2012 doi:10.2903/j.efsa.2012.2917
+Bixafen 581809-46-3 single chemical entity Component is identical to the substance Bixafen 581809-46-3 N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide Bixafen C18H12Cl2F3N3O FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1 InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Bixafen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen 05Nov2012 2012 doi:10.2903/j.efsa.2012.2917
+Bixafen 581809-46-3 single chemical entity Component is identical to the substance Bixafen 581809-46-3 N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide Bixafen C18H12Cl2F3N3O FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1 InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Bixafen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen 05Nov2012 2012 doi:10.2903/j.efsa.2012.2917
+Bixafen 581809-46-3 single chemical entity Component is identical to the substance Bixafen 581809-46-3 N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide Bixafen C18H12Cl2F3N3O FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1 InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Bixafen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen 05Nov2012 2012 doi:10.2903/j.efsa.2012.2917
+Bixafen 581809-46-3 single chemical entity Component is identical to the substance Bixafen 581809-46-3 N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide Bixafen C18H12Cl2F3N3O FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1 InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Negative RMS: The United Kingdom Bixafen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen 05Nov2012 2012 doi:10.2903/j.efsa.2012.2917
+Bixafen 581809-46-3 single chemical entity Component is identical to the substance Bixafen 581809-46-3 N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide Bixafen C18H12Cl2F3N3O FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1 InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: The United Kingdom Bixafen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen 05Nov2012 2012 doi:10.2903/j.efsa.2012.2917
+Bixafen 581809-46-3 single chemical entity Component is identical to the substance Bixafen 581809-46-3 N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide Bixafen C18H12Cl2F3N3O FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1 InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Bixafen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen 05Nov2012 2012 doi:10.2903/j.efsa.2012.2917
+Bixafen 581809-46-3 single chemical entity Component is identical to the substance Bixafen 581809-46-3 N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide Bixafen C18H12Cl2F3N3O FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1 InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Bixafen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen 05Nov2012 2012 doi:10.2903/j.efsa.2012.2917
+Bixafen 581809-46-3 single chemical entity Component is identical to the substance Bixafen 581809-46-3 N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide Bixafen C18H12Cl2F3N3O FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1 InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 5 Male intraperitoneal 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: The United Kingdom Bixafen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen 05Nov2012 2012 doi:10.2903/j.efsa.2012.2917
+Bromadiolone 249-205-9 28772-56-7 single chemical entity Component is identical to the substance Bromadiolone 249-205-9 28772-56-7 3-[3-[4-(4-Bromophenyl)phenyl]-3-hydroxy-1-phenylpropyl]-4- hydroxychromen-2-one Bromadiolone C30H23BrO4 C1=CC=C(C=C1)C(CC(C2=CC=C(C=C2)C3=CC=C(C=C3)Br)O)C4=C(C5=CC=CC=C5OC4=O)O InChI=1S/C30H23BrO4/c31-23-16-14-20(15-17-23)19-10-12-22(13-11-19)26(32)18-25(21-6-2-1-3-7-21)28-29(33)24-8-4-5-9-27(24)35-30(28)34/h1-17,25-26,32-33H,18H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Sweden Bromadiolone 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bromadiolone 13Oct2010 2010 doi:10.2903/j.efsa.2010.1783
+Bromadiolone 249-205-9 28772-56-7 single chemical entity Component is identical to the substance Bromadiolone 249-205-9 28772-56-7 3-[3-[4-(4-Bromophenyl)phenyl]-3-hydroxy-1-phenylpropyl]-4- hydroxychromen-2-one Bromadiolone C30H23BrO4 C1=CC=C(C=C1)C(CC(C2=CC=C(C=C2)C3=CC=C(C=C3)Br)O)C4=C(C5=CC=CC=C5OC4=O)O InChI=1S/C30H23BrO4/c31-23-16-14-20(15-17-23)19-10-12-22(13-11-19)26(32)18-25(21-6-2-1-3-7-21)28-29(33)24-8-4-5-9-27(24)35-30(28)34/h1-17,25-26,32-33H,18H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Sweden Bromadiolone 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bromadiolone 13Oct2010 2010 doi:10.2903/j.efsa.2010.1783
+Bromadiolone 249-205-9 28772-56-7 single chemical entity Component is identical to the substance Bromadiolone 249-205-9 28772-56-7 3-[3-[4-(4-Bromophenyl)phenyl]-3-hydroxy-1-phenylpropyl]-4- hydroxychromen-2-one Bromadiolone C30H23BrO4 C1=CC=C(C=C1)C(CC(C2=CC=C(C=C2)C3=CC=C(C=C3)Br)O)C4=C(C5=CC=CC=C5OC4=O)O InChI=1S/C30H23BrO4/c31-23-16-14-20(15-17-23)19-10-12-22(13-11-19)26(32)18-25(21-6-2-1-3-7-21)28-29(33)24-8-4-5-9-27(24)35-30(28)34/h1-17,25-26,32-33H,18H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Sweden Bromadiolone 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bromadiolone 13Oct2010 2010 doi:10.2903/j.efsa.2010.1783
+Bromadiolone 249-205-9 28772-56-7 single chemical entity Component is identical to the substance Bromadiolone 249-205-9 28772-56-7 3-[3-[4-(4-Bromophenyl)phenyl]-3-hydroxy-1-phenylpropyl]-4- hydroxychromen-2-one Bromadiolone C30H23BrO4 C1=CC=C(C=C1)C(CC(C2=CC=C(C=C2)C3=CC=C(C=C3)Br)O)C4=C(C5=CC=CC=C5OC4=O)O InChI=1S/C30H23BrO4/c31-23-16-14-20(15-17-23)19-10-12-22(13-11-19)26(32)18-25(21-6-2-1-3-7-21)28-29(33)24-8-4-5-9-27(24)35-30(28)34/h1-17,25-26,32-33H,18H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Sweden Bromadiolone 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bromadiolone 13Oct2010 2010 doi:10.2903/j.efsa.2010.1783
+Bromadiolone 249-205-9 28772-56-7 single chemical entity Component is identical to the substance Bromadiolone 249-205-9 28772-56-7 3-[3-[4-(4-Bromophenyl)phenyl]-3-hydroxy-1-phenylpropyl]-4- hydroxychromen-2-one Bromadiolone C30H23BrO4 C1=CC=C(C=C1)C(CC(C2=CC=C(C=C2)C3=CC=C(C=C3)Br)O)C4=C(C5=CC=CC=C5OC4=O)O InChI=1S/C30H23BrO4/c31-23-16-14-20(15-17-23)19-10-12-22(13-11-19)26(32)18-25(21-6-2-1-3-7-21)28-29(33)24-8-4-5-9-27(24)35-30(28)34/h1-17,25-26,32-33H,18H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Sweden Bromadiolone 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bromadiolone 13Oct2010 2010 doi:10.2903/j.efsa.2010.1783
+Bromadiolone 249-205-9 28772-56-7 single chemical entity Component is identical to the substance Bromadiolone 249-205-9 28772-56-7 3-[3-[4-(4-Bromophenyl)phenyl]-3-hydroxy-1-phenylpropyl]-4- hydroxychromen-2-one Bromadiolone C30H23BrO4 C1=CC=C(C=C1)C(CC(C2=CC=C(C=C2)C3=CC=C(C=C3)Br)O)C4=C(C5=CC=CC=C5OC4=O)O InChI=1S/C30H23BrO4/c31-23-16-14-20(15-17-23)19-10-12-22(13-11-19)26(32)18-25(21-6-2-1-3-7-21)28-29(33)24-8-4-5-9-27(24)35-30(28)34/h1-17,25-26,32-33H,18H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Sweden Bromadiolone 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bromadiolone 13Oct2010 2010 doi:10.2903/j.efsa.2010.1783
+Bromadiolone 249-205-9 28772-56-7 single chemical entity Component is identical to the substance Bromadiolone 249-205-9 28772-56-7 3-[3-[4-(4-Bromophenyl)phenyl]-3-hydroxy-1-phenylpropyl]-4- hydroxychromen-2-one Bromadiolone C30H23BrO4 C1=CC=C(C=C1)C(CC(C2=CC=C(C=C2)C3=CC=C(C=C3)Br)O)C4=C(C5=CC=CC=C5OC4=O)O InChI=1S/C30H23BrO4/c31-23-16-14-20(15-17-23)19-10-12-22(13-11-19)26(32)18-25(21-6-2-1-3-7-21)28-29(33)24-8-4-5-9-27(24)35-30(28)34/h1-17,25-26,32-33H,18H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Sweden Bromadiolone 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bromadiolone 13Oct2010 2010 doi:10.2903/j.efsa.2010.1783
+Bromadiolone 249-205-9 28772-56-7 single chemical entity Component is identical to the substance Bromadiolone 249-205-9 28772-56-7 3-[3-[4-(4-Bromophenyl)phenyl]-3-hydroxy-1-phenylpropyl]-4- hydroxychromen-2-one Bromadiolone C30H23BrO4 C1=CC=C(C=C1)C(CC(C2=CC=C(C=C2)C3=CC=C(C=C3)Br)O)C4=C(C5=CC=CC=C5OC4=O)O InChI=1S/C30H23BrO4/c31-23-16-14-20(15-17-23)19-10-12-22(13-11-19)26(32)18-25(21-6-2-1-3-7-21)28-29(33)24-8-4-5-9-27(24)35-30(28)34/h1-17,25-26,32-33H,18H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Sweden Bromadiolone 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bromadiolone 13Oct2010 2010 doi:10.2903/j.efsa.2010.1783
+Bromadiolone 249-205-9 28772-56-7 single chemical entity Component is identical to the substance Bromadiolone 249-205-9 28772-56-7 3-[3-[4-(4-Bromophenyl)phenyl]-3-hydroxy-1-phenylpropyl]-4- hydroxychromen-2-one Bromadiolone C30H23BrO4 C1=CC=C(C=C1)C(CC(C2=CC=C(C=C2)C3=CC=C(C=C3)Br)O)C4=C(C5=CC=CC=C5OC4=O)O InChI=1S/C30H23BrO4/c31-23-16-14-20(15-17-23)19-10-12-22(13-11-19)26(32)18-25(21-6-2-1-3-7-21)28-29(33)24-8-4-5-9-27(24)35-30(28)34/h1-17,25-26,32-33H,18H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Sweden Bromadiolone 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bromadiolone 13Oct2010 2010 doi:10.2903/j.efsa.2010.1783
+Bromadiolone 249-205-9 28772-56-7 single chemical entity Component is identical to the substance Bromadiolone 249-205-9 28772-56-7 3-[3-[4-(4-Bromophenyl)phenyl]-3-hydroxy-1-phenylpropyl]-4- hydroxychromen-2-one Bromadiolone C30H23BrO4 C1=CC=C(C=C1)C(CC(C2=CC=C(C=C2)C3=CC=C(C=C3)Br)O)C4=C(C5=CC=CC=C5OC4=O)O InChI=1S/C30H23BrO4/c31-23-16-14-20(15-17-23)19-10-12-22(13-11-19)26(32)18-25(21-6-2-1-3-7-21)28-29(33)24-8-4-5-9-27(24)35-30(28)34/h1-17,25-26,32-33H,18H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Sweden Bromadiolone 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bromadiolone 13Oct2010 2010 doi:10.2903/j.efsa.2010.1783
+Bromadiolone 249-205-9 28772-56-7 single chemical entity Component is identical to the substance Bromadiolone 249-205-9 28772-56-7 3-[3-[4-(4-Bromophenyl)phenyl]-3-hydroxy-1-phenylpropyl]-4- hydroxychromen-2-one Bromadiolone C30H23BrO4 C1=CC=C(C=C1)C(CC(C2=CC=C(C=C2)C3=CC=C(C=C3)Br)O)C4=C(C5=CC=CC=C5OC4=O)O InChI=1S/C30H23BrO4/c31-23-16-14-20(15-17-23)19-10-12-22(13-11-19)26(32)18-25(21-6-2-1-3-7-21)28-29(33)24-8-4-5-9-27(24)35-30(28)34/h1-17,25-26,32-33H,18H2 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Sweden Bromadiolone 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bromadiolone 13Oct2010 2010 doi:10.2903/j.efsa.2010.1783
+Bromadiolone 249-205-9 28772-56-7 single chemical entity Component is identical to the substance Bromadiolone 249-205-9 28772-56-7 3-[3-[4-(4-Bromophenyl)phenyl]-3-hydroxy-1-phenylpropyl]-4- hydroxychromen-2-one Bromadiolone C30H23BrO4 C1=CC=C(C=C1)C(CC(C2=CC=C(C=C2)C3=CC=C(C=C3)Br)O)C4=C(C5=CC=CC=C5OC4=O)O InChI=1S/C30H23BrO4/c31-23-16-14-20(15-17-23)19-10-12-22(13-11-19)26(32)18-25(21-6-2-1-3-7-21)28-29(33)24-8-4-5-9-27(24)35-30(28)34/h1-17,25-26,32-33H,18H2 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Sweden Bromadiolone 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bromadiolone 13Oct2010 2010 doi:10.2903/j.efsa.2010.1783
+Bromadiolone 249-205-9 28772-56-7 single chemical entity Component is identical to the substance Bromadiolone 249-205-9 28772-56-7 3-[3-[4-(4-Bromophenyl)phenyl]-3-hydroxy-1-phenylpropyl]-4- hydroxychromen-2-one Bromadiolone C30H23BrO4 C1=CC=C(C=C1)C(CC(C2=CC=C(C=C2)C3=CC=C(C=C3)Br)O)C4=C(C5=CC=CC=C5OC4=O)O InChI=1S/C30H23BrO4/c31-23-16-14-20(15-17-23)19-10-12-22(13-11-19)26(32)18-25(21-6-2-1-3-7-21)28-29(33)24-8-4-5-9-27(24)35-30(28)34/h1-17,25-26,32-33H,18H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Sweden Bromadiolone 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bromadiolone 13Oct2010 2010 doi:10.2903/j.efsa.2010.1783
+Bromadiolone 249-205-9 28772-56-7 single chemical entity Component is identical to the substance Bromadiolone 249-205-9 28772-56-7 3-[3-[4-(4-Bromophenyl)phenyl]-3-hydroxy-1-phenylpropyl]-4- hydroxychromen-2-one Bromadiolone C30H23BrO4 C1=CC=C(C=C1)C(CC(C2=CC=C(C=C2)C3=CC=C(C=C3)Br)O)C4=C(C5=CC=CC=C5OC4=O)O InChI=1S/C30H23BrO4/c31-23-16-14-20(15-17-23)19-10-12-22(13-11-19)26(32)18-25(21-6-2-1-3-7-21)28-29(33)24-8-4-5-9-27(24)35-30(28)34/h1-17,25-26,32-33H,18H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Sweden Bromadiolone 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bromadiolone 13Oct2010 2010 doi:10.2903/j.efsa.2010.1783
+Bromadiolone 249-205-9 28772-56-7 single chemical entity Component is identical to the substance Bromadiolone 249-205-9 28772-56-7 3-[3-[4-(4-Bromophenyl)phenyl]-3-hydroxy-1-phenylpropyl]-4- hydroxychromen-2-one Bromadiolone C30H23BrO4 C1=CC=C(C=C1)C(CC(C2=CC=C(C=C2)C3=CC=C(C=C3)Br)O)C4=C(C5=CC=CC=C5OC4=O)O InChI=1S/C30H23BrO4/c31-23-16-14-20(15-17-23)19-10-12-22(13-11-19)26(32)18-25(21-6-2-1-3-7-21)28-29(33)24-8-4-5-9-27(24)35-30(28)34/h1-17,25-26,32-33H,18H2 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) ICR 10 Male/Female intraperitoneal 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Sweden Bromadiolone 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bromadiolone 13Oct2010 2010 doi:10.2903/j.efsa.2010.1783
+Bromuconazole 116255-48-2 single chemical entity Component is identical to the substance Bromuconazole 116255-48-2 2,5-anhydro-4-bromo-1,3,4-trideoxy-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)pentitol Bromuconazole (sum of diasteroisomers) C13H12BrCl2N3O BrC1CC(CN2N=CN=C2)(C3=C(Cl)C=C(Cl)C=C3)OC1 InChI=1S/C13H12BrCl2N3O/c14-9-4-13(20-5-9,6-19-8-17-7-18-19)11-2-1-10(15)3-12(11)16/h1-3,7-9H,4-6H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium Bromuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole 27Aug2010 2010 doi:10.2903/j.efsa.2010.1704
+Bromuconazole 116255-48-2 single chemical entity Component is identical to the substance Bromuconazole 116255-48-2 2,5-anhydro-4-bromo-1,3,4-trideoxy-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)pentitol Bromuconazole (sum of diasteroisomers) C13H12BrCl2N3O BrC1CC(CN2N=CN=C2)(C3=C(Cl)C=C(Cl)C=C3)OC1 InChI=1S/C13H12BrCl2N3O/c14-9-4-13(20-5-9,6-19-8-17-7-18-19)11-2-1-10(15)3-12(11)16/h1-3,7-9H,4-6H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium Bromuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole 27Aug2010 2010 doi:10.2903/j.efsa.2010.1704
+Bromuconazole 116255-48-2 single chemical entity Component is identical to the substance Bromuconazole 116255-48-2 2,5-anhydro-4-bromo-1,3,4-trideoxy-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)pentitol Bromuconazole (sum of diasteroisomers) C13H12BrCl2N3O BrC1CC(CN2N=CN=C2)(C3=C(Cl)C=C(Cl)C=C3)OC1 InChI=1S/C13H12BrCl2N3O/c14-9-4-13(20-5-9,6-19-8-17-7-18-19)11-2-1-10(15)3-12(11)16/h1-3,7-9H,4-6H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Belgium Bromuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole 27Aug2010 2010 doi:10.2903/j.efsa.2010.1704
+Bromuconazole 116255-48-2 single chemical entity Component is identical to the substance Bromuconazole 116255-48-2 2,5-anhydro-4-bromo-1,3,4-trideoxy-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)pentitol Bromuconazole (sum of diasteroisomers) C13H12BrCl2N3O BrC1CC(CN2N=CN=C2)(C3=C(Cl)C=C(Cl)C=C3)OC1 InChI=1S/C13H12BrCl2N3O/c14-9-4-13(20-5-9,6-19-8-17-7-18-19)11-2-1-10(15)3-12(11)16/h1-3,7-9H,4-6H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium Bromuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole 27Aug2010 2010 doi:10.2903/j.efsa.2010.1704
+Bromuconazole 116255-48-2 single chemical entity Component is identical to the substance Bromuconazole 116255-48-2 2,5-anhydro-4-bromo-1,3,4-trideoxy-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)pentitol Bromuconazole (sum of diasteroisomers) C13H12BrCl2N3O BrC1CC(CN2N=CN=C2)(C3=C(Cl)C=C(Cl)C=C3)OC1 InChI=1S/C13H12BrCl2N3O/c14-9-4-13(20-5-9,6-19-8-17-7-18-19)11-2-1-10(15)3-12(11)16/h1-3,7-9H,4-6H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium Bromuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole 27Aug2010 2010 doi:10.2903/j.efsa.2010.1704
+Bromuconazole 116255-48-2 single chemical entity Component is identical to the substance Bromuconazole 116255-48-2 2,5-anhydro-4-bromo-1,3,4-trideoxy-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)pentitol Bromuconazole (sum of diasteroisomers) C13H12BrCl2N3O BrC1CC(CN2N=CN=C2)(C3=C(Cl)C=C(Cl)C=C3)OC1 InChI=1S/C13H12BrCl2N3O/c14-9-4-13(20-5-9,6-19-8-17-7-18-19)11-2-1-10(15)3-12(11)16/h1-3,7-9H,4-6H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Belgium Bromuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole 27Aug2010 2010 doi:10.2903/j.efsa.2010.1704
+Bromuconazole 116255-48-2 single chemical entity Component is identical to the substance Bromuconazole 116255-48-2 2,5-anhydro-4-bromo-1,3,4-trideoxy-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)pentitol Bromuconazole (sum of diasteroisomers) C13H12BrCl2N3O BrC1CC(CN2N=CN=C2)(C3=C(Cl)C=C(Cl)C=C3)OC1 InChI=1S/C13H12BrCl2N3O/c14-9-4-13(20-5-9,6-19-8-17-7-18-19)11-2-1-10(15)3-12(11)16/h1-3,7-9H,4-6H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Belgium Bromuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole 27Aug2010 2010 doi:10.2903/j.efsa.2010.1704
+Bromuconazole 116255-48-2 single chemical entity Component is identical to the substance Bromuconazole 116255-48-2 2,5-anhydro-4-bromo-1,3,4-trideoxy-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)pentitol Bromuconazole (sum of diasteroisomers) C13H12BrCl2N3O BrC1CC(CN2N=CN=C2)(C3=C(Cl)C=C(Cl)C=C3)OC1 InChI=1S/C13H12BrCl2N3O/c14-9-4-13(20-5-9,6-19-8-17-7-18-19)11-2-1-10(15)3-12(11)16/h1-3,7-9H,4-6H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium Bromuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole 27Aug2010 2010 doi:10.2903/j.efsa.2010.1704
+Bromuconazole 116255-48-2 single chemical entity Component is identical to the substance Bromuconazole 116255-48-2 2,5-anhydro-4-bromo-1,3,4-trideoxy-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)pentitol Bromuconazole (sum of diasteroisomers) C13H12BrCl2N3O BrC1CC(CN2N=CN=C2)(C3=C(Cl)C=C(Cl)C=C3)OC1 InChI=1S/C13H12BrCl2N3O/c14-9-4-13(20-5-9,6-19-8-17-7-18-19)11-2-1-10(15)3-12(11)16/h1-3,7-9H,4-6H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium Bromuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole 27Aug2010 2010 doi:10.2903/j.efsa.2010.1704
+Bromuconazole 116255-48-2 single chemical entity Component is identical to the substance Bromuconazole 116255-48-2 2,5-anhydro-4-bromo-1,3,4-trideoxy-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)pentitol Bromuconazole (sum of diasteroisomers) C13H12BrCl2N3O BrC1CC(CN2N=CN=C2)(C3=C(Cl)C=C(Cl)C=C3)OC1 InChI=1S/C13H12BrCl2N3O/c14-9-4-13(20-5-9,6-19-8-17-7-18-19)11-2-1-10(15)3-12(11)16/h1-3,7-9H,4-6H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium Bromuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole 27Aug2010 2010 doi:10.2903/j.efsa.2010.1704
+Bromuconazole 116255-48-2 single chemical entity Component is identical to the substance Bromuconazole 116255-48-2 2,5-anhydro-4-bromo-1,3,4-trideoxy-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)pentitol Bromuconazole (sum of diasteroisomers) C13H12BrCl2N3O BrC1CC(CN2N=CN=C2)(C3=C(Cl)C=C(Cl)C=C3)OC1 InChI=1S/C13H12BrCl2N3O/c14-9-4-13(20-5-9,6-19-8-17-7-18-19)11-2-1-10(15)3-12(11)16/h1-3,7-9H,4-6H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium Bromuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole 27Aug2010 2010 doi:10.2903/j.efsa.2010.1704
+Bromuconazole 116255-48-2 single chemical entity Component is identical to the substance Bromuconazole 116255-48-2 2,5-anhydro-4-bromo-1,3,4-trideoxy-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)pentitol Bromuconazole (sum of diasteroisomers) C13H12BrCl2N3O BrC1CC(CN2N=CN=C2)(C3=C(Cl)C=C(Cl)C=C3)OC1 InChI=1S/C13H12BrCl2N3O/c14-9-4-13(20-5-9,6-19-8-17-7-18-19)11-2-1-10(15)3-12(11)16/h1-3,7-9H,4-6H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Belgium Bromuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole 27Aug2010 2010 doi:10.2903/j.efsa.2010.1704
+Bromuconazole 116255-48-2 single chemical entity Component is identical to the substance Bromuconazole 116255-48-2 2,5-anhydro-4-bromo-1,3,4-trideoxy-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)pentitol Bromuconazole (sum of diasteroisomers) C13H12BrCl2N3O BrC1CC(CN2N=CN=C2)(C3=C(Cl)C=C(Cl)C=C3)OC1 InChI=1S/C13H12BrCl2N3O/c14-9-4-13(20-5-9,6-19-8-17-7-18-19)11-2-1-10(15)3-12(11)16/h1-3,7-9H,4-6H2 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Ambiguous no information RMS: Belgium Bromuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole 27Aug2010 2010 doi:10.2903/j.efsa.2010.1704
+Bromuconazole 116255-48-2 single chemical entity Component is identical to the substance Bromuconazole 116255-48-2 2,5-anhydro-4-bromo-1,3,4-trideoxy-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)pentitol Bromuconazole (sum of diasteroisomers) C13H12BrCl2N3O BrC1CC(CN2N=CN=C2)(C3=C(Cl)C=C(Cl)C=C3)OC1 InChI=1S/C13H12BrCl2N3O/c14-9-4-13(20-5-9,6-19-8-17-7-18-19)11-2-1-10(15)3-12(11)16/h1-3,7-9H,4-6H2 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Belgium Bromuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole 27Aug2010 2010 doi:10.2903/j.efsa.2010.1704
+Bromuconazole 116255-48-2 single chemical entity Component is identical to the substance Bromuconazole 116255-48-2 2,5-anhydro-4-bromo-1,3,4-trideoxy-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)pentitol Bromuconazole (sum of diasteroisomers) C13H12BrCl2N3O BrC1CC(CN2N=CN=C2)(C3=C(Cl)C=C(Cl)C=C3)OC1 InChI=1S/C13H12BrCl2N3O/c14-9-4-13(20-5-9,6-19-8-17-7-18-19)11-2-1-10(15)3-12(11)16/h1-3,7-9H,4-6H2 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: Belgium Bromuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole 27Aug2010 2010 doi:10.2903/j.efsa.2010.1704
+Bromuconazole 116255-48-2 single chemical entity Component is identical to the substance Bromuconazole 116255-48-2 2,5-anhydro-4-bromo-1,3,4-trideoxy-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)pentitol Bromuconazole (sum of diasteroisomers) C13H12BrCl2N3O BrC1CC(CN2N=CN=C2)(C3=C(Cl)C=C(Cl)C=C3)OC1 InChI=1S/C13H12BrCl2N3O/c14-9-4-13(20-5-9,6-19-8-17-7-18-19)11-2-1-10(15)3-12(11)16/h1-3,7-9H,4-6H2 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: Belgium Bromuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole 27Aug2010 2010 doi:10.2903/j.efsa.2010.1704
+Bromuconazole 116255-48-2 single chemical entity Component is identical to the substance Bromuconazole 116255-48-2 2,5-anhydro-4-bromo-1,3,4-trideoxy-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)pentitol Bromuconazole (sum of diasteroisomers) C13H12BrCl2N3O BrC1CC(CN2N=CN=C2)(C3=C(Cl)C=C(Cl)C=C3)OC1 InChI=1S/C13H12BrCl2N3O/c14-9-4-13(20-5-9,6-19-8-17-7-18-19)11-2-1-10(15)3-12(11)16/h1-3,7-9H,4-6H2 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Positive RMS: Belgium Bromuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole 27Aug2010 2010 doi:10.2903/j.efsa.2010.1704
+Bromuconazole 116255-48-2 single chemical entity Component is identical to the substance Bromuconazole 116255-48-2 2,5-anhydro-4-bromo-1,3,4-trideoxy-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)pentitol Bromuconazole (sum of diasteroisomers) C13H12BrCl2N3O BrC1CC(CN2N=CN=C2)(C3=C(Cl)C=C(Cl)C=C3)OC1 InChI=1S/C13H12BrCl2N3O/c14-9-4-13(20-5-9,6-19-8-17-7-18-19)11-2-1-10(15)3-12(11)16/h1-3,7-9H,4-6H2 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Positive RMS: Belgium Bromuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole 27Aug2010 2010 doi:10.2903/j.efsa.2010.1704
+Bromuconazole 116255-48-2 single chemical entity Component is identical to the substance Bromuconazole 116255-48-2 2,5-anhydro-4-bromo-1,3,4-trideoxy-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)pentitol Bromuconazole (sum of diasteroisomers) C13H12BrCl2N3O BrC1CC(CN2N=CN=C2)(C3=C(Cl)C=C(Cl)C=C3)OC1 InChI=1S/C13H12BrCl2N3O/c14-9-4-13(20-5-9,6-19-8-17-7-18-19)11-2-1-10(15)3-12(11)16/h1-3,7-9H,4-6H2 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Belgium Bromuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole 27Aug2010 2010 doi:10.2903/j.efsa.2010.1704
+Bromuconazole 116255-48-2 single chemical entity Component is identical to the substance Bromuconazole 116255-48-2 2,5-anhydro-4-bromo-1,3,4-trideoxy-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)pentitol Bromuconazole (sum of diasteroisomers) C13H12BrCl2N3O BrC1CC(CN2N=CN=C2)(C3=C(Cl)C=C(Cl)C=C3)OC1 InChI=1S/C13H12BrCl2N3O/c14-9-4-13(20-5-9,6-19-8-17-7-18-19)11-2-1-10(15)3-12(11)16/h1-3,7-9H,4-6H2 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Positive RMS: Belgium Bromuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole 27Aug2010 2010 doi:10.2903/j.efsa.2010.1704
+Bromuconazole 116255-48-2 single chemical entity Component is identical to the substance Bromuconazole 116255-48-2 2,5-anhydro-4-bromo-1,3,4-trideoxy-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)pentitol Bromuconazole (sum of diasteroisomers) C13H12BrCl2N3O BrC1CC(CN2N=CN=C2)(C3=C(Cl)C=C(Cl)C=C3)OC1 InChI=1S/C13H12BrCl2N3O/c14-9-4-13(20-5-9,6-19-8-17-7-18-19)11-2-1-10(15)3-12(11)16/h1-3,7-9H,4-6H2 organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Belgium Bromuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole 27Aug2010 2010 doi:10.2903/j.efsa.2010.1704
+Bromuconazole 116255-48-2 single chemical entity Component is identical to the substance Bromuconazole 116255-48-2 2,5-anhydro-4-bromo-1,3,4-trideoxy-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)pentitol Bromuconazole (sum of diasteroisomers) C13H12BrCl2N3O BrC1CC(CN2N=CN=C2)(C3=C(Cl)C=C(Cl)C=C3)OC1 InChI=1S/C13H12BrCl2N3O/c14-9-4-13(20-5-9,6-19-8-17-7-18-19)11-2-1-10(15)3-12(11)16/h1-3,7-9H,4-6H2 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Not reported 5 Male oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Belgium Bromuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole 27Aug2010 2010 doi:10.2903/j.efsa.2010.1704
+Bromuconazole 116255-48-2 single chemical entity Component is identical to the substance Bromuconazole 116255-48-2 2,5-anhydro-4-bromo-1,3,4-trideoxy-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)pentitol Bromuconazole (sum of diasteroisomers) C13H12BrCl2N3O BrC1CC(CN2N=CN=C2)(C3=C(Cl)C=C(Cl)C=C3)OC1 InChI=1S/C13H12BrCl2N3O/c14-9-4-13(20-5-9,6-19-8-17-7-18-19)11-2-1-10(15)3-12(11)16/h1-3,7-9H,4-6H2 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Not reported 5 Male oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Belgium Bromuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole 27Aug2010 2010 doi:10.2903/j.efsa.2010.1704
+Bromuconazole 116255-48-2 single chemical entity Component is identical to the substance Bromuconazole 116255-48-2 2,5-anhydro-4-bromo-1,3,4-trideoxy-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)pentitol Bromuconazole (sum of diasteroisomers) C13H12BrCl2N3O BrC1CC(CN2N=CN=C2)(C3=C(Cl)C=C(Cl)C=C3)OC1 InChI=1S/C13H12BrCl2N3O/c14-9-4-13(20-5-9,6-19-8-17-7-18-19)11-2-1-10(15)3-12(11)16/h1-3,7-9H,4-6H2 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Not reported 5 Male oral: gavage 72.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Belgium Bromuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole 27Aug2010 2010 doi:10.2903/j.efsa.2010.1704
+Bromuconazole 116255-48-2 single chemical entity Component is identical to the substance Bromuconazole 116255-48-2 2,5-anhydro-4-bromo-1,3,4-trideoxy-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)pentitol Bromuconazole (sum of diasteroisomers) C13H12BrCl2N3O BrC1CC(CN2N=CN=C2)(C3=C(Cl)C=C(Cl)C=C3)OC1 InChI=1S/C13H12BrCl2N3O/c14-9-4-13(20-5-9,6-19-8-17-7-18-19)11-2-1-10(15)3-12(11)16/h1-3,7-9H,4-6H2 organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Wistar 12 Male/Female oral: gavage 14.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Belgium Bromuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole 27Aug2010 2010 doi:10.2903/j.efsa.2010.1704
+Bromuconazole 116255-48-2 single chemical entity Component is identical to the substance Bromuconazole 116255-48-2 2,5-anhydro-4-bromo-1,3,4-trideoxy-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)pentitol Bromuconazole (sum of diasteroisomers) C13H12BrCl2N3O BrC1CC(CN2N=CN=C2)(C3=C(Cl)C=C(Cl)C=C3)OC1 InChI=1S/C13H12BrCl2N3O/c14-9-4-13(20-5-9,6-19-8-17-7-18-19)11-2-1-10(15)3-12(11)16/h1-3,7-9H,4-6H2 organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Wistar 12 Male/Female oral: gavage 4.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Belgium Bromuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole 27Aug2010 2010 doi:10.2903/j.efsa.2010.1704
+Bupirimate 255-391-2 41483-43-6 single chemical entity Component is identical to the substance Bupirimate 255-391-2 41483-43-6 5-butyl-2-(ethylamino)-6-methylpyrimidin-4-yl dimethylsulfamate Bupirimate C13H24N4O3S O=S(OC1=C(CCCC)C(C)=NC(NCC)=N1)(N(C)C)=O InChI=1S/C13H24N4O3S/c1-6-8-9-11-10(3)15-13(14-7-2)16-12(11)20-21(18,19)17(4)5/h6-9H2,1-5H3,(H,14,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The Netherlands Bupirimate (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate 05Oct2010 2010 doi:10.2903/j.efsa.2010.1786
+Bupirimate 255-391-2 41483-43-6 single chemical entity Component is identical to the substance Bupirimate 255-391-2 41483-43-6 5-butyl-2-(ethylamino)-6-methylpyrimidin-4-yl dimethylsulfamate Bupirimate C13H24N4O3S O=S(OC1=C(CCCC)C(C)=NC(NCC)=N1)(N(C)C)=O InChI=1S/C13H24N4O3S/c1-6-8-9-11-10(3)15-13(14-7-2)16-12(11)20-21(18,19)17(4)5/h6-9H2,1-5H3,(H,14,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The Netherlands Bupirimate (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate 05Oct2010 2010 doi:10.2903/j.efsa.2010.1786
+Bupirimate 255-391-2 41483-43-6 single chemical entity Component is identical to the substance Bupirimate 255-391-2 41483-43-6 5-butyl-2-(ethylamino)-6-methylpyrimidin-4-yl dimethylsulfamate Bupirimate C13H24N4O3S O=S(OC1=C(CCCC)C(C)=NC(NCC)=N1)(N(C)C)=O InChI=1S/C13H24N4O3S/c1-6-8-9-11-10(3)15-13(14-7-2)16-12(11)20-21(18,19)17(4)5/h6-9H2,1-5H3,(H,14,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: The Netherlands Bupirimate (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate 05Oct2010 2010 doi:10.2903/j.efsa.2010.1786
+Bupirimate 255-391-2 41483-43-6 single chemical entity Component is identical to the substance Bupirimate 255-391-2 41483-43-6 5-butyl-2-(ethylamino)-6-methylpyrimidin-4-yl dimethylsulfamate Bupirimate C13H24N4O3S O=S(OC1=C(CCCC)C(C)=NC(NCC)=N1)(N(C)C)=O InChI=1S/C13H24N4O3S/c1-6-8-9-11-10(3)15-13(14-7-2)16-12(11)20-21(18,19)17(4)5/h6-9H2,1-5H3,(H,14,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The Netherlands Bupirimate (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate 05Oct2010 2010 doi:10.2903/j.efsa.2010.1786
+Bupirimate 255-391-2 41483-43-6 single chemical entity Component is identical to the substance Bupirimate 255-391-2 41483-43-6 5-butyl-2-(ethylamino)-6-methylpyrimidin-4-yl dimethylsulfamate Bupirimate C13H24N4O3S O=S(OC1=C(CCCC)C(C)=NC(NCC)=N1)(N(C)C)=O InChI=1S/C13H24N4O3S/c1-6-8-9-11-10(3)15-13(14-7-2)16-12(11)20-21(18,19)17(4)5/h6-9H2,1-5H3,(H,14,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The Netherlands Bupirimate (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate 05Oct2010 2010 doi:10.2903/j.efsa.2010.1786
+Bupirimate 255-391-2 41483-43-6 single chemical entity Component is identical to the substance Bupirimate 255-391-2 41483-43-6 5-butyl-2-(ethylamino)-6-methylpyrimidin-4-yl dimethylsulfamate Bupirimate C13H24N4O3S O=S(OC1=C(CCCC)C(C)=NC(NCC)=N1)(N(C)C)=O InChI=1S/C13H24N4O3S/c1-6-8-9-11-10(3)15-13(14-7-2)16-12(11)20-21(18,19)17(4)5/h6-9H2,1-5H3,(H,14,15,16) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Negative no information RMS: The Netherlands Bupirimate (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate 05Oct2010 2010 doi:10.2903/j.efsa.2010.1786
+Bupirimate 255-391-2 41483-43-6 single chemical entity Component is identical to the substance Bupirimate 255-391-2 41483-43-6 5-butyl-2-(ethylamino)-6-methylpyrimidin-4-yl dimethylsulfamate Bupirimate C13H24N4O3S O=S(OC1=C(CCCC)C(C)=NC(NCC)=N1)(N(C)C)=O InChI=1S/C13H24N4O3S/c1-6-8-9-11-10(3)15-13(14-7-2)16-12(11)20-21(18,19)17(4)5/h6-9H2,1-5H3,(H,14,15,16) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative no information RMS: The Netherlands Bupirimate (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate 05Oct2010 2010 doi:10.2903/j.efsa.2010.1786
+Bupirimate 255-391-2 41483-43-6 single chemical entity Component is identical to the substance Bupirimate 255-391-2 41483-43-6 5-butyl-2-(ethylamino)-6-methylpyrimidin-4-yl dimethylsulfamate Bupirimate C13H24N4O3S O=S(OC1=C(CCCC)C(C)=NC(NCC)=N1)(N(C)C)=O InChI=1S/C13H24N4O3S/c1-6-8-9-11-10(3)15-13(14-7-2)16-12(11)20-21(18,19)17(4)5/h6-9H2,1-5H3,(H,14,15,16) organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Human (as organism) fibroblast Not reported yes without Negative RMS: The Netherlands Bupirimate (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate 05Oct2010 2010 doi:10.2903/j.efsa.2010.1786
+Bupirimate 255-391-2 41483-43-6 single chemical entity Component is identical to the substance Bupirimate 255-391-2 41483-43-6 5-butyl-2-(ethylamino)-6-methylpyrimidin-4-yl dimethylsulfamate Bupirimate C13H24N4O3S O=S(OC1=C(CCCC)C(C)=NC(NCC)=N1)(N(C)C)=O InChI=1S/C13H24N4O3S/c1-6-8-9-11-10(3)15-13(14-7-2)16-12(11)20-21(18,19)17(4)5/h6-9H2,1-5H3,(H,14,15,16) organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Human (as organism) fibroblast Not reported yes with Negative RMS: The Netherlands Bupirimate (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate 05Oct2010 2010 doi:10.2903/j.efsa.2010.1786
+Bupirimate 255-391-2 41483-43-6 single chemical entity Component is identical to the substance Bupirimate 255-391-2 41483-43-6 5-butyl-2-(ethylamino)-6-methylpyrimidin-4-yl dimethylsulfamate Bupirimate C13H24N4O3S O=S(OC1=C(CCCC)C(C)=NC(NCC)=N1)(N(C)C)=O InChI=1S/C13H24N4O3S/c1-6-8-9-11-10(3)15-13(14-7-2)16-12(11)20-21(18,19)17(4)5/h6-9H2,1-5H3,(H,14,15,16) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes without Positive RMS: The Netherlands Bupirimate (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate 05Oct2010 2010 doi:10.2903/j.efsa.2010.1786
+Bupirimate 255-391-2 41483-43-6 single chemical entity Component is identical to the substance Bupirimate 255-391-2 41483-43-6 5-butyl-2-(ethylamino)-6-methylpyrimidin-4-yl dimethylsulfamate Bupirimate C13H24N4O3S O=S(OC1=C(CCCC)C(C)=NC(NCC)=N1)(N(C)C)=O InChI=1S/C13H24N4O3S/c1-6-8-9-11-10(3)15-13(14-7-2)16-12(11)20-21(18,19)17(4)5/h6-9H2,1-5H3,(H,14,15,16) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes with Negative RMS: The Netherlands Bupirimate (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate 05Oct2010 2010 doi:10.2903/j.efsa.2010.1786
+Bupirimate 255-391-2 41483-43-6 single chemical entity Component is identical to the substance Bupirimate 255-391-2 41483-43-6 5-butyl-2-(ethylamino)-6-methylpyrimidin-4-yl dimethylsulfamate Bupirimate C13H24N4O3S O=S(OC1=C(CCCC)C(C)=NC(NCC)=N1)(N(C)C)=O InChI=1S/C13H24N4O3S/c1-6-8-9-11-10(3)15-13(14-7-2)16-12(11)20-21(18,19)17(4)5/h6-9H2,1-5H3,(H,14,15,16) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) C57BL 10 Male/Female oral: gavage 72.0000000000 h yes not applicable Negative direct evidence-cytotoxicity$indirect evidence-systemic toxicity RMS: The Netherlands Bupirimate (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate 05Oct2010 2010 doi:10.2903/j.efsa.2010.1786
+Bupirimate 255-391-2 41483-43-6 single chemical entity Component is identical to the substance Bupirimate 255-391-2 41483-43-6 5-butyl-2-(ethylamino)-6-methylpyrimidin-4-yl dimethylsulfamate Bupirimate C13H24N4O3S O=S(OC1=C(CCCC)C(C)=NC(NCC)=N1)(N(C)C)=O InChI=1S/C13H24N4O3S/c1-6-8-9-11-10(3)15-13(14-7-2)16-12(11)20-21(18,19)17(4)5/h6-9H2,1-5H3,(H,14,15,16) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) C57BL 10 Male/Female oral: gavage 48.0000000000 h yes not applicable Negative direct evidence-cytotoxicity$indirect evidence-systemic toxicity RMS: The Netherlands Bupirimate (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate 05Oct2010 2010 doi:10.2903/j.efsa.2010.1786
+Bupirimate 255-391-2 41483-43-6 single chemical entity Component is identical to the substance Bupirimate 255-391-2 41483-43-6 5-butyl-2-(ethylamino)-6-methylpyrimidin-4-yl dimethylsulfamate Bupirimate C13H24N4O3S O=S(OC1=C(CCCC)C(C)=NC(NCC)=N1)(N(C)C)=O InChI=1S/C13H24N4O3S/c1-6-8-9-11-10(3)15-13(14-7-2)16-12(11)20-21(18,19)17(4)5/h6-9H2,1-5H3,(H,14,15,16) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) C57BL 10 Male/Female oral: gavage 24.0000000000 h yes not applicable Negative direct evidence-cytotoxicity$indirect evidence-systemic toxicity RMS: The Netherlands Bupirimate (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate 05Oct2010 2010 doi:10.2903/j.efsa.2010.1786
+Bupirimate 255-391-2 41483-43-6 single chemical entity Component is identical to the substance Bupirimate 255-391-2 41483-43-6 5-butyl-2-(ethylamino)-6-methylpyrimidin-4-yl dimethylsulfamate Bupirimate C13H24N4O3S O=S(OC1=C(CCCC)C(C)=NC(NCC)=N1)(N(C)C)=O InChI=1S/C13H24N4O3S/c1-6-8-9-11-10(3)15-13(14-7-2)16-12(11)20-21(18,19)17(4)5/h6-9H2,1-5H3,(H,14,15,16) organic compound Other Other chromosome aberration dominant lethal assay in vivo According to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) No Acceptable House mouse (as animal) CD-1 15 Male oral: gavage 5.0000000000 D yes not applicable Negative RMS: The Netherlands Bupirimate (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate 05Oct2010 2010 doi:10.2903/j.efsa.2010.1786
+Bupirimate 255-391-2 41483-43-6 single chemical entity Component is a metabolite of the substance Ethirimol 245-949-3 5-butyl-2-(ethylamino)-6-methyl-1H-pyrimidin-4-one Not in list C11H19N3O CCCCC1=C(NC(=NC1=O)NCC)C InChI=1S/C11H19N3O/c1-4-6-7-9-8(3)13-11(12-5-2)14-10(9)15/h4-7H2,1-3H3,(H2,12,13,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The Netherlands Bupirimate (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate 05Oct2010 2010 doi:10.2903/j.efsa.2010.1786
+Bupirimate 255-391-2 41483-43-6 single chemical entity Component is a metabolite of the substance Ethirimol 245-949-3 5-butyl-2-(ethylamino)-6-methyl-1H-pyrimidin-4-one Not in list C11H19N3O CCCCC1=C(NC(=NC1=O)NCC)C InChI=1S/C11H19N3O/c1-4-6-7-9-8(3)13-11(12-5-2)14-10(9)15/h4-7H2,1-3H3,(H2,12,13,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The Netherlands Bupirimate (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate 05Oct2010 2010 doi:10.2903/j.efsa.2010.1786
+Bupirimate 255-391-2 41483-43-6 single chemical entity Component is a metabolite of the substance Ethirimol 245-949-3 5-butyl-2-(ethylamino)-6-methyl-1H-pyrimidin-4-one Not in list C11H19N3O CCCCC1=C(NC(=NC1=O)NCC)C InChI=1S/C11H19N3O/c1-4-6-7-9-8(3)13-11(12-5-2)14-10(9)15/h4-7H2,1-3H3,(H2,12,13,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The Netherlands Bupirimate (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate 05Oct2010 2010 doi:10.2903/j.efsa.2010.1786
+Bupirimate 255-391-2 41483-43-6 single chemical entity Component is a metabolite of the substance Ethirimol 245-949-3 5-butyl-2-(ethylamino)-6-methyl-1H-pyrimidin-4-one Not in list C11H19N3O CCCCC1=C(NC(=NC1=O)NCC)C InChI=1S/C11H19N3O/c1-4-6-7-9-8(3)13-11(12-5-2)14-10(9)15/h4-7H2,1-3H3,(H2,12,13,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: The Netherlands Bupirimate (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate 05Oct2010 2010 doi:10.2903/j.efsa.2010.1786
+Bupirimate 255-391-2 41483-43-6 single chemical entity Component is a metabolite of the substance Ethirimol 245-949-3 5-butyl-2-(ethylamino)-6-methyl-1H-pyrimidin-4-one Not in list C11H19N3O CCCCC1=C(NC(=NC1=O)NCC)C InChI=1S/C11H19N3O/c1-4-6-7-9-8(3)13-11(12-5-2)14-10(9)15/h4-7H2,1-3H3,(H2,12,13,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The Netherlands Bupirimate (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate 05Oct2010 2010 doi:10.2903/j.efsa.2010.1786
+Bupirimate 255-391-2 41483-43-6 single chemical entity Component is a metabolite of the substance Ethirimol 245-949-3 5-butyl-2-(ethylamino)-6-methyl-1H-pyrimidin-4-one Not in list C11H19N3O CCCCC1=C(NC(=NC1=O)NCC)C InChI=1S/C11H19N3O/c1-4-6-7-9-8(3)13-11(12-5-2)14-10(9)15/h4-7H2,1-3H3,(H2,12,13,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: The Netherlands Bupirimate (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate 05Oct2010 2010 doi:10.2903/j.efsa.2010.1786
+Bupirimate 255-391-2 41483-43-6 single chemical entity Component is a metabolite of the substance Ethirimol 245-949-3 5-butyl-2-(ethylamino)-6-methyl-1H-pyrimidin-4-one Not in list C11H19N3O CCCCC1=C(NC(=NC1=O)NCC)C InChI=1S/C11H19N3O/c1-4-6-7-9-8(3)13-11(12-5-2)14-10(9)15/h4-7H2,1-3H3,(H2,12,13,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The Netherlands Bupirimate (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate 05Oct2010 2010 doi:10.2903/j.efsa.2010.1786
+Bupirimate 255-391-2 41483-43-6 single chemical entity Component is a metabolite of the substance Ethirimol 245-949-3 5-butyl-2-(ethylamino)-6-methyl-1H-pyrimidin-4-one Not in list C11H19N3O CCCCC1=C(NC(=NC1=O)NCC)C InChI=1S/C11H19N3O/c1-4-6-7-9-8(3)13-11(12-5-2)14-10(9)15/h4-7H2,1-3H3,(H2,12,13,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The Netherlands Bupirimate (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate 05Oct2010 2010 doi:10.2903/j.efsa.2010.1786
+Bupirimate 255-391-2 41483-43-6 single chemical entity Component is a metabolite of the substance Ethirimol 245-949-3 5-butyl-2-(ethylamino)-6-methyl-1H-pyrimidin-4-one Not in list C11H19N3O CCCCC1=C(NC(=NC1=O)NCC)C InChI=1S/C11H19N3O/c1-4-6-7-9-8(3)13-11(12-5-2)14-10(9)15/h4-7H2,1-3H3,(H2,12,13,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The Netherlands Bupirimate (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate 05Oct2010 2010 doi:10.2903/j.efsa.2010.1786
+Bupirimate 255-391-2 41483-43-6 single chemical entity Component is a metabolite of the substance Ethirimol 245-949-3 5-butyl-2-(ethylamino)-6-methyl-1H-pyrimidin-4-one Not in list C11H19N3O CCCCC1=C(NC(=NC1=O)NCC)C InChI=1S/C11H19N3O/c1-4-6-7-9-8(3)13-11(12-5-2)14-10(9)15/h4-7H2,1-3H3,(H2,12,13,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The Netherlands Bupirimate (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate 05Oct2010 2010 doi:10.2903/j.efsa.2010.1786
+Bupirimate 255-391-2 41483-43-6 single chemical entity Component is a metabolite of the substance Ethirimol 245-949-3 5-butyl-2-(ethylamino)-6-methyl-1H-pyrimidin-4-one Not in list C11H19N3O CCCCC1=C(NC(=NC1=O)NCC)C InChI=1S/C11H19N3O/c1-4-6-7-9-8(3)13-11(12-5-2)14-10(9)15/h4-7H2,1-3H3,(H2,12,13,14,15) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes with Negative RMS: The Netherlands Bupirimate (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate 05Oct2010 2010 doi:10.2903/j.efsa.2010.1786
+Bupirimate 255-391-2 41483-43-6 single chemical entity Component is a metabolite of the substance Ethirimol 245-949-3 5-butyl-2-(ethylamino)-6-methyl-1H-pyrimidin-4-one Not in list C11H19N3O CCCCC1=C(NC(=NC1=O)NCC)C InChI=1S/C11H19N3O/c1-4-6-7-9-8(3)13-11(12-5-2)14-10(9)15/h4-7H2,1-3H3,(H2,12,13,14,15) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes without Negative RMS: The Netherlands Bupirimate (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate 05Oct2010 2010 doi:10.2903/j.efsa.2010.1786
+Bupirimate 255-391-2 41483-43-6 single chemical entity Component is a metabolite of the substance Ethirimol 245-949-3 5-butyl-2-(ethylamino)-6-methyl-1H-pyrimidin-4-one Not in list C11H19N3O CCCCC1=C(NC(=NC1=O)NCC)C InChI=1S/C11H19N3O/c1-4-6-7-9-8(3)13-11(12-5-2)14-10(9)15/h4-7H2,1-3H3,(H2,12,13,14,15) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) C57BL 10 Male/Female oral: gavage 24.0000000000 h yes not applicable Negative indirect evidence-systemic toxicity RMS: The Netherlands Bupirimate (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate 05Oct2010 2010 doi:10.2903/j.efsa.2010.1786
+Bupirimate 255-391-2 41483-43-6 single chemical entity Component is a metabolite of the substance Ethirimol 245-949-3 5-butyl-2-(ethylamino)-6-methyl-1H-pyrimidin-4-one Not in list C11H19N3O CCCCC1=C(NC(=NC1=O)NCC)C InChI=1S/C11H19N3O/c1-4-6-7-9-8(3)13-11(12-5-2)14-10(9)15/h4-7H2,1-3H3,(H2,12,13,14,15) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) C57BL 10 Male/Female oral: gavage 48.0000000000 h yes not applicable Negative indirect evidence-systemic toxicity RMS: The Netherlands Bupirimate (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate 05Oct2010 2010 doi:10.2903/j.efsa.2010.1786
+Bupirimate 255-391-2 41483-43-6 single chemical entity Component is a metabolite of the substance Ethirimol 245-949-3 5-butyl-2-(ethylamino)-6-methyl-1H-pyrimidin-4-one Not in list C11H19N3O CCCCC1=C(NC(=NC1=O)NCC)C InChI=1S/C11H19N3O/c1-4-6-7-9-8(3)13-11(12-5-2)14-10(9)15/h4-7H2,1-3H3,(H2,12,13,14,15) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) Yes Acceptable House mouse (as animal) CD-1 15 Male oral: gavage 5.0000000000 D yes not applicable Negative RMS: The Netherlands Bupirimate (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate 05Oct2010 2010 doi:10.2903/j.efsa.2010.1786
+Buprofezin 69327-76-0 single chemical entity Component is identical to the substance Buprofezin 69327-76-0 2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one Buprofezin C16H23N3OS O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Finland Buprofezin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is identical to the substance Buprofezin 69327-76-0 2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one Buprofezin C16H23N3OS O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Finland Buprofezin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is identical to the substance Buprofezin 69327-76-0 2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one Buprofezin C16H23N3OS O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Finland Buprofezin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is identical to the substance Buprofezin 69327-76-0 2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one Buprofezin C16H23N3OS O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Finland Buprofezin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is identical to the substance Buprofezin 69327-76-0 2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one Buprofezin C16H23N3OS O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3 organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes without Negative RMS: Finland Buprofezin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is identical to the substance Buprofezin 69327-76-0 2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one Buprofezin C16H23N3OS O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Finland Buprofezin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is identical to the substance Buprofezin 69327-76-0 2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one Buprofezin C16H23N3OS O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Finland Buprofezin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is identical to the substance Buprofezin 69327-76-0 2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one Buprofezin C16H23N3OS O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Finland Buprofezin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is identical to the substance Buprofezin 69327-76-0 2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one Buprofezin C16H23N3OS O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Finland Buprofezin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is identical to the substance Buprofezin 69327-76-0 2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one Buprofezin C16H23N3OS O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Finland Buprofezin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is identical to the substance Buprofezin 69327-76-0 2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one Buprofezin C16H23N3OS O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Finland Buprofezin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is identical to the substance Buprofezin 69327-76-0 2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one Buprofezin C16H23N3OS O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Finland Buprofezin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is identical to the substance Buprofezin 69327-76-0 2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one Buprofezin C16H23N3OS O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Finland Buprofezin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is identical to the substance Buprofezin 69327-76-0 2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one Buprofezin C16H23N3OS O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3 organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes without Negative RMS: Finland Buprofezin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is identical to the substance Buprofezin 69327-76-0 2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one Buprofezin C16H23N3OS O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Finland Buprofezin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is identical to the substance Buprofezin 69327-76-0 2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one Buprofezin C16H23N3OS O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Finland Buprofezin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is identical to the substance Buprofezin 69327-76-0 2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one Buprofezin C16H23N3OS O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Finland Buprofezin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is identical to the substance Buprofezin 69327-76-0 2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one Buprofezin C16H23N3OS O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Finland Buprofezin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is identical to the substance Buprofezin 69327-76-0 2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one Buprofezin C16H23N3OS O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Finland Buprofezin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is identical to the substance Buprofezin 69327-76-0 2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one Buprofezin C16H23N3OS O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Finland Buprofezin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is identical to the substance Buprofezin 69327-76-0 2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one Buprofezin C16H23N3OS O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Finland Buprofezin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is identical to the substance Buprofezin 69327-76-0 2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one Buprofezin C16H23N3OS O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Finland Buprofezin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is identical to the substance Buprofezin 69327-76-0 2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one Buprofezin C16H23N3OS O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Finland Buprofezin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is identical to the substance Buprofezin 69327-76-0 2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one Buprofezin C16H23N3OS O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Finland Buprofezin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is identical to the substance Buprofezin 69327-76-0 2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one Buprofezin C16H23N3OS O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Finland Buprofezin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is identical to the substance Buprofezin 69327-76-0 2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one Buprofezin C16H23N3OS O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Finland Buprofezin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is identical to the substance Buprofezin 69327-76-0 2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one Buprofezin C16H23N3OS O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Finland Buprofezin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is identical to the substance Buprofezin 69327-76-0 2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one Buprofezin C16H23N3OS O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Finland Buprofezin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is identical to the substance Buprofezin 69327-76-0 2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one Buprofezin C16H23N3OS O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3 organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Finland Buprofezin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is identical to the substance Buprofezin 69327-76-0 2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one Buprofezin C16H23N3OS O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) BDF1 mouse 12 Male/Female oral: unspecified 24.0000000000 h yes not applicable Negative no evidence RMS: Finland Buprofezin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is identical to the substance Buprofezin 69327-76-0 2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one Buprofezin C16H23N3OS O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) BDF1 mouse 12 Male/Female oral: unspecified 12.0000000000 h yes not applicable Negative no evidence RMS: Finland Buprofezin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is identical to the substance Buprofezin 69327-76-0 2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one Buprofezin C16H23N3OS O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) BDF1 mouse 12 Male/Female oral: unspecified 72.0000000000 h yes not applicable Negative no evidence RMS: Finland Buprofezin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is identical to the substance Buprofezin 69327-76-0 2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one Buprofezin C16H23N3OS O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) BDF1 mouse 12 Male/Female oral: unspecified 48.0000000000 h yes not applicable Negative no evidence RMS: Finland Buprofezin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Cadusafos 95465-99-9 single chemical entity Component is identical to the substance Cadusafos 95465-99-9 2-[Butan-2-ylsulfanyl(ethoxy)phosphoryl]sulfanylbutane Cadusafos C10H23O2PS2 CCC(C)SP(=O)(OCC)SC(C)CC InChI=1S/C10H23O2PS2/c1-6-9(4)14-13(11,12-8-3)15-10(5)7-2/h9-10H,6-8H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Greece Cadusafos 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cadusafos 20May2009 2009 doi:10.2903/j.efsa.2009.262r
+Cadusafos 95465-99-9 single chemical entity Component is identical to the substance Cadusafos 95465-99-9 2-[Butan-2-ylsulfanyl(ethoxy)phosphoryl]sulfanylbutane Cadusafos C10H23O2PS2 CCC(C)SP(=O)(OCC)SC(C)CC InChI=1S/C10H23O2PS2/c1-6-9(4)14-13(11,12-8-3)15-10(5)7-2/h9-10H,6-8H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Greece Cadusafos 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cadusafos 20May2009 2009 doi:10.2903/j.efsa.2009.262r
+Cadusafos 95465-99-9 single chemical entity Component is identical to the substance Cadusafos 95465-99-9 2-[Butan-2-ylsulfanyl(ethoxy)phosphoryl]sulfanylbutane Cadusafos C10H23O2PS2 CCC(C)SP(=O)(OCC)SC(C)CC InChI=1S/C10H23O2PS2/c1-6-9(4)14-13(11,12-8-3)15-10(5)7-2/h9-10H,6-8H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Greece Cadusafos 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cadusafos 20May2009 2009 doi:10.2903/j.efsa.2009.262r
+Cadusafos 95465-99-9 single chemical entity Component is identical to the substance Cadusafos 95465-99-9 2-[Butan-2-ylsulfanyl(ethoxy)phosphoryl]sulfanylbutane Cadusafos C10H23O2PS2 CCC(C)SP(=O)(OCC)SC(C)CC InChI=1S/C10H23O2PS2/c1-6-9(4)14-13(11,12-8-3)15-10(5)7-2/h9-10H,6-8H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Greece Cadusafos 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cadusafos 20May2009 2009 doi:10.2903/j.efsa.2009.262r
+Cadusafos 95465-99-9 single chemical entity Component is identical to the substance Cadusafos 95465-99-9 2-[Butan-2-ylsulfanyl(ethoxy)phosphoryl]sulfanylbutane Cadusafos C10H23O2PS2 CCC(C)SP(=O)(OCC)SC(C)CC InChI=1S/C10H23O2PS2/c1-6-9(4)14-13(11,12-8-3)15-10(5)7-2/h9-10H,6-8H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Greece Cadusafos 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cadusafos 20May2009 2009 doi:10.2903/j.efsa.2009.262r
+Cadusafos 95465-99-9 single chemical entity Component is identical to the substance Cadusafos 95465-99-9 2-[Butan-2-ylsulfanyl(ethoxy)phosphoryl]sulfanylbutane Cadusafos C10H23O2PS2 CCC(C)SP(=O)(OCC)SC(C)CC InChI=1S/C10H23O2PS2/c1-6-9(4)14-13(11,12-8-3)15-10(5)7-2/h9-10H,6-8H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Greece Cadusafos 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cadusafos 20May2009 2009 doi:10.2903/j.efsa.2009.262r
+Cadusafos 95465-99-9 single chemical entity Component is identical to the substance Cadusafos 95465-99-9 2-[Butan-2-ylsulfanyl(ethoxy)phosphoryl]sulfanylbutane Cadusafos C10H23O2PS2 CCC(C)SP(=O)(OCC)SC(C)CC InChI=1S/C10H23O2PS2/c1-6-9(4)14-13(11,12-8-3)15-10(5)7-2/h9-10H,6-8H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Greece Cadusafos 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cadusafos 20May2009 2009 doi:10.2903/j.efsa.2009.262r
+Cadusafos 95465-99-9 single chemical entity Component is identical to the substance Cadusafos 95465-99-9 2-[Butan-2-ylsulfanyl(ethoxy)phosphoryl]sulfanylbutane Cadusafos C10H23O2PS2 CCC(C)SP(=O)(OCC)SC(C)CC InChI=1S/C10H23O2PS2/c1-6-9(4)14-13(11,12-8-3)15-10(5)7-2/h9-10H,6-8H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Greece Cadusafos 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cadusafos 20May2009 2009 doi:10.2903/j.efsa.2009.262r
+Cadusafos 95465-99-9 single chemical entity Component is identical to the substance Cadusafos 95465-99-9 2-[Butan-2-ylsulfanyl(ethoxy)phosphoryl]sulfanylbutane Cadusafos C10H23O2PS2 CCC(C)SP(=O)(OCC)SC(C)CC InChI=1S/C10H23O2PS2/c1-6-9(4)14-13(11,12-8-3)15-10(5)7-2/h9-10H,6-8H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Greece Cadusafos 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cadusafos 20May2009 2009 doi:10.2903/j.efsa.2009.262r
+Cadusafos 95465-99-9 single chemical entity Component is identical to the substance Cadusafos 95465-99-9 2-[Butan-2-ylsulfanyl(ethoxy)phosphoryl]sulfanylbutane Cadusafos C10H23O2PS2 CCC(C)SP(=O)(OCC)SC(C)CC InChI=1S/C10H23O2PS2/c1-6-9(4)14-13(11,12-8-3)15-10(5)7-2/h9-10H,6-8H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Greece Cadusafos 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cadusafos 20May2009 2009 doi:10.2903/j.efsa.2009.262r
+Cadusafos 95465-99-9 single chemical entity Component is identical to the substance Cadusafos 95465-99-9 2-[Butan-2-ylsulfanyl(ethoxy)phosphoryl]sulfanylbutane Cadusafos C10H23O2PS2 CCC(C)SP(=O)(OCC)SC(C)CC InChI=1S/C10H23O2PS2/c1-6-9(4)14-13(11,12-8-3)15-10(5)7-2/h9-10H,6-8H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes without Inconclusive RMS: Greece Cadusafos 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cadusafos 20May2009 2009 doi:10.2903/j.efsa.2009.262r
+Cadusafos 95465-99-9 single chemical entity Component is identical to the substance Cadusafos 95465-99-9 2-[Butan-2-ylsulfanyl(ethoxy)phosphoryl]sulfanylbutane Cadusafos C10H23O2PS2 CCC(C)SP(=O)(OCC)SC(C)CC InChI=1S/C10H23O2PS2/c1-6-9(4)14-13(11,12-8-3)15-10(5)7-2/h9-10H,6-8H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes with Inconclusive RMS: Greece Cadusafos 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cadusafos 20May2009 2009 doi:10.2903/j.efsa.2009.262r
+Cadusafos 95465-99-9 single chemical entity Component is identical to the substance Cadusafos 95465-99-9 2-[Butan-2-ylsulfanyl(ethoxy)phosphoryl]sulfanylbutane Cadusafos C10H23O2PS2 CCC(C)SP(=O)(OCC)SC(C)CC InChI=1S/C10H23O2PS2/c1-6-9(4)14-13(11,12-8-3)15-10(5)7-2/h9-10H,6-8H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: Greece Cadusafos 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cadusafos 20May2009 2009 doi:10.2903/j.efsa.2009.262r
+Cadusafos 95465-99-9 single chemical entity Component is identical to the substance Cadusafos 95465-99-9 2-[Butan-2-ylsulfanyl(ethoxy)phosphoryl]sulfanylbutane Cadusafos C10H23O2PS2 CCC(C)SP(=O)(OCC)SC(C)CC InChI=1S/C10H23O2PS2/c1-6-9(4)14-13(11,12-8-3)15-10(5)7-2/h9-10H,6-8H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: Greece Cadusafos 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cadusafos 20May2009 2009 doi:10.2903/j.efsa.2009.262r
+Cadusafos 95465-99-9 single chemical entity Component is identical to the substance Cadusafos 95465-99-9 2-[Butan-2-ylsulfanyl(ethoxy)phosphoryl]sulfanylbutane Cadusafos C10H23O2PS2 CCC(C)SP(=O)(OCC)SC(C)CC InChI=1S/C10H23O2PS2/c1-6-9(4)14-13(11,12-8-3)15-10(5)7-2/h9-10H,6-8H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Rat (as animal) hepatocytes Not reported yes without Negative RMS: Greece Cadusafos 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cadusafos 20May2009 2009 doi:10.2903/j.efsa.2009.262r
+Cadusafos 95465-99-9 single chemical entity Component is identical to the substance Cadusafos 95465-99-9 2-[Butan-2-ylsulfanyl(ethoxy)phosphoryl]sulfanylbutane Cadusafos C10H23O2PS2 CCC(C)SP(=O)(OCC)SC(C)CC InChI=1S/C10H23O2PS2/c1-6-9(4)14-13(11,12-8-3)15-10(5)7-2/h9-10H,6-8H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: Greece Cadusafos 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cadusafos 20May2009 2009 doi:10.2903/j.efsa.2009.262r
+Cadusafos 95465-99-9 single chemical entity Component is identical to the substance Cadusafos 95465-99-9 2-[Butan-2-ylsulfanyl(ethoxy)phosphoryl]sulfanylbutane Cadusafos C10H23O2PS2 CCC(C)SP(=O)(OCC)SC(C)CC InChI=1S/C10H23O2PS2/c1-6-9(4)14-13(11,12-8-3)15-10(5)7-2/h9-10H,6-8H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: Greece Cadusafos 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cadusafos 20May2009 2009 doi:10.2903/j.efsa.2009.262r
+Cadusafos 95465-99-9 single chemical entity Component is identical to the substance Cadusafos 95465-99-9 2-[Butan-2-ylsulfanyl(ethoxy)phosphoryl]sulfanylbutane Cadusafos C10H23O2PS2 CCC(C)SP(=O)(OCC)SC(C)CC InChI=1S/C10H23O2PS2/c1-6-9(4)14-13(11,12-8-3)15-10(5)7-2/h9-10H,6-8H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair in vitro mammalian cell transformation assay in vitro No guideline available Not reported Not applicable Acceptable House mouse (as animal) 3T3 Not reported yes with Positive RMS: Greece Cadusafos 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cadusafos 20May2009 2009 doi:10.2903/j.efsa.2009.262r
+Cadusafos 95465-99-9 single chemical entity Component is identical to the substance Cadusafos 95465-99-9 2-[Butan-2-ylsulfanyl(ethoxy)phosphoryl]sulfanylbutane Cadusafos C10H23O2PS2 CCC(C)SP(=O)(OCC)SC(C)CC InChI=1S/C10H23O2PS2/c1-6-9(4)14-13(11,12-8-3)15-10(5)7-2/h9-10H,6-8H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair in vitro mammalian cell transformation assay in vitro No guideline available Not reported Not applicable Acceptable House mouse (as animal) 3T3 Not reported yes without Negative RMS: Greece Cadusafos 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cadusafos 20May2009 2009 doi:10.2903/j.efsa.2009.262r
+Cadusafos 95465-99-9 single chemical entity Component is identical to the substance Cadusafos 95465-99-9 2-[Butan-2-ylsulfanyl(ethoxy)phosphoryl]sulfanylbutane Cadusafos C10H23O2PS2 CCC(C)SP(=O)(OCC)SC(C)CC InChI=1S/C10H23O2PS2/c1-6-9(4)14-13(11,12-8-3)15-10(5)7-2/h9-10H,6-8H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Sprague-Dawley 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Greece Cadusafos 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cadusafos 20May2009 2009 doi:10.2903/j.efsa.2009.262r
+Cadusafos 95465-99-9 single chemical entity Component is identical to the substance Cadusafos 95465-99-9 2-[Butan-2-ylsulfanyl(ethoxy)phosphoryl]sulfanylbutane Cadusafos C10H23O2PS2 CCC(C)SP(=O)(OCC)SC(C)CC InChI=1S/C10H23O2PS2/c1-6-9(4)14-13(11,12-8-3)15-10(5)7-2/h9-10H,6-8H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Sprague-Dawley 10 Male/Female oral: gavage 6.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Greece Cadusafos 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cadusafos 20May2009 2009 doi:10.2903/j.efsa.2009.262r
+Cadusafos 95465-99-9 single chemical entity Component is identical to the substance Cadusafos 95465-99-9 2-[Butan-2-ylsulfanyl(ethoxy)phosphoryl]sulfanylbutane Cadusafos C10H23O2PS2 CCC(C)SP(=O)(OCC)SC(C)CC InChI=1S/C10H23O2PS2/c1-6-9(4)14-13(11,12-8-3)15-10(5)7-2/h9-10H,6-8H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Sprague-Dawley 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Greece Cadusafos 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cadusafos 20May2009 2009 doi:10.2903/j.efsa.2009.262r
+Cadusafos 95465-99-9 single chemical entity Component is identical to the substance Cadusafos 95465-99-9 2-[Butan-2-ylsulfanyl(ethoxy)phosphoryl]sulfanylbutane Cadusafos C10H23O2PS2 CCC(C)SP(=O)(OCC)SC(C)CC InChI=1S/C10H23O2PS2/c1-6-9(4)14-13(11,12-8-3)15-10(5)7-2/h9-10H,6-8H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Greece Cadusafos (Addendum 3) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cadusafos 20May2009 2009 doi:10.2903/j.efsa.2009.262r
+Cadusafos 95465-99-9 single chemical entity Component is identical to the substance Cadusafos 95465-99-9 2-[Butan-2-ylsulfanyl(ethoxy)phosphoryl]sulfanylbutane Cadusafos C10H23O2PS2 CCC(C)SP(=O)(OCC)SC(C)CC InChI=1S/C10H23O2PS2/c1-6-9(4)14-13(11,12-8-3)15-10(5)7-2/h9-10H,6-8H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Greece Cadusafos (Addendum 3) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cadusafos 20May2009 2009 doi:10.2903/j.efsa.2009.262r
+Cadusafos 95465-99-9 single chemical entity Component is identical to the substance Cadusafos 95465-99-9 2-[Butan-2-ylsulfanyl(ethoxy)phosphoryl]sulfanylbutane Cadusafos C10H23O2PS2 CCC(C)SP(=O)(OCC)SC(C)CC InChI=1S/C10H23O2PS2/c1-6-9(4)14-13(11,12-8-3)15-10(5)7-2/h9-10H,6-8H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Greece Cadusafos (Addendum 3) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cadusafos 20May2009 2009 doi:10.2903/j.efsa.2009.262r
+Cadusafos 95465-99-9 single chemical entity Component is identical to the substance Cadusafos 95465-99-9 2-[Butan-2-ylsulfanyl(ethoxy)phosphoryl]sulfanylbutane Cadusafos C10H23O2PS2 CCC(C)SP(=O)(OCC)SC(C)CC InChI=1S/C10H23O2PS2/c1-6-9(4)14-13(11,12-8-3)15-10(5)7-2/h9-10H,6-8H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Greece Cadusafos (Addendum 3) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cadusafos 20May2009 2009 doi:10.2903/j.efsa.2009.262r
+Cadusafos 95465-99-9 single chemical entity Component is identical to the substance Cadusafos 95465-99-9 2-[Butan-2-ylsulfanyl(ethoxy)phosphoryl]sulfanylbutane Cadusafos C10H23O2PS2 CCC(C)SP(=O)(OCC)SC(C)CC InChI=1S/C10H23O2PS2/c1-6-9(4)14-13(11,12-8-3)15-10(5)7-2/h9-10H,6-8H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Greece Cadusafos (Addendum 3) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cadusafos 20May2009 2009 doi:10.2903/j.efsa.2009.262r
+Cadusafos 95465-99-9 single chemical entity Component is identical to the substance Cadusafos 95465-99-9 2-[Butan-2-ylsulfanyl(ethoxy)phosphoryl]sulfanylbutane Cadusafos C10H23O2PS2 CCC(C)SP(=O)(OCC)SC(C)CC InChI=1S/C10H23O2PS2/c1-6-9(4)14-13(11,12-8-3)15-10(5)7-2/h9-10H,6-8H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Greece Cadusafos (Addendum 3) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cadusafos 20May2009 2009 doi:10.2903/j.efsa.2009.262r
+Cadusafos 95465-99-9 single chemical entity Component is identical to the substance Cadusafos 95465-99-9 2-[Butan-2-ylsulfanyl(ethoxy)phosphoryl]sulfanylbutane Cadusafos C10H23O2PS2 CCC(C)SP(=O)(OCC)SC(C)CC InChI=1S/C10H23O2PS2/c1-6-9(4)14-13(11,12-8-3)15-10(5)7-2/h9-10H,6-8H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Greece Cadusafos (Addendum 3) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cadusafos 20May2009 2009 doi:10.2903/j.efsa.2009.262r
+Cadusafos 95465-99-9 single chemical entity Component is identical to the substance Cadusafos 95465-99-9 2-[Butan-2-ylsulfanyl(ethoxy)phosphoryl]sulfanylbutane Cadusafos C10H23O2PS2 CCC(C)SP(=O)(OCC)SC(C)CC InChI=1S/C10H23O2PS2/c1-6-9(4)14-13(11,12-8-3)15-10(5)7-2/h9-10H,6-8H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Greece Cadusafos (Addendum 3) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cadusafos 20May2009 2009 doi:10.2903/j.efsa.2009.262r
+Cadusafos 95465-99-9 single chemical entity Component is identical to the substance Cadusafos 95465-99-9 2-[Butan-2-ylsulfanyl(ethoxy)phosphoryl]sulfanylbutane Cadusafos C10H23O2PS2 CCC(C)SP(=O)(OCC)SC(C)CC InChI=1S/C10H23O2PS2/c1-6-9(4)14-13(11,12-8-3)15-10(5)7-2/h9-10H,6-8H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Greece Cadusafos (Addendum 3) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cadusafos 20May2009 2009 doi:10.2903/j.efsa.2009.262r
+Cadusafos 95465-99-9 single chemical entity Component is identical to the substance Cadusafos 95465-99-9 2-[Butan-2-ylsulfanyl(ethoxy)phosphoryl]sulfanylbutane Cadusafos C10H23O2PS2 CCC(C)SP(=O)(OCC)SC(C)CC InChI=1S/C10H23O2PS2/c1-6-9(4)14-13(11,12-8-3)15-10(5)7-2/h9-10H,6-8H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Greece Cadusafos (Addendum 3) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cadusafos 20May2009 2009 doi:10.2903/j.efsa.2009.262r
+Captan 205-087-0 133-06-2 single chemical entity Component is identical to the substance Captan 205-087-0 133-06-2 2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione Captan C9H8Cl3NO2S ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Positive RMS: Italy Captan 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance captan 22Oct2009 2009 doi:10.2903/j.efsa.2009.296r
+Captan 205-087-0 133-06-2 single chemical entity Component is identical to the substance Captan 205-087-0 133-06-2 2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione Captan C9H8Cl3NO2S ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Positive RMS: Italy Captan 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance captan 22Oct2009 2009 doi:10.2903/j.efsa.2009.296r
+Captan 205-087-0 133-06-2 single chemical entity Component is identical to the substance Captan 205-087-0 133-06-2 2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione Captan C9H8Cl3NO2S ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1536 Not reported yes with Negative RMS: Italy Captan 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance captan 22Oct2009 2009 doi:10.2903/j.efsa.2009.296r
+Captan 205-087-0 133-06-2 single chemical entity Component is identical to the substance Captan 205-087-0 133-06-2 2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione Captan C9H8Cl3NO2S ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Italy Captan 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance captan 22Oct2009 2009 doi:10.2903/j.efsa.2009.296r
+Captan 205-087-0 133-06-2 single chemical entity Component is identical to the substance Captan 205-087-0 133-06-2 2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione Captan C9H8Cl3NO2S ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: Italy Captan 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance captan 22Oct2009 2009 doi:10.2903/j.efsa.2009.296r
+Captan 205-087-0 133-06-2 single chemical entity Component is identical to the substance Captan 205-087-0 133-06-2 2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione Captan C9H8Cl3NO2S ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Italy Captan 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance captan 22Oct2009 2009 doi:10.2903/j.efsa.2009.296r
+Captan 205-087-0 133-06-2 single chemical entity Component is identical to the substance Captan 205-087-0 133-06-2 2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione Captan C9H8Cl3NO2S ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Positive RMS: Italy Captan 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance captan 22Oct2009 2009 doi:10.2903/j.efsa.2009.296r
+Captan 205-087-0 133-06-2 single chemical entity Component is identical to the substance Captan 205-087-0 133-06-2 2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione Captan C9H8Cl3NO2S ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1536 Not reported yes without Negative RMS: Italy Captan 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance captan 22Oct2009 2009 doi:10.2903/j.efsa.2009.296r
+Captan 205-087-0 133-06-2 single chemical entity Component is identical to the substance Captan 205-087-0 133-06-2 2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione Captan C9H8Cl3NO2S ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: Italy Captan 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance captan 22Oct2009 2009 doi:10.2903/j.efsa.2009.296r
+Captan 205-087-0 133-06-2 single chemical entity Component is identical to the substance Captan 205-087-0 133-06-2 2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione Captan C9H8Cl3NO2S ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2 organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Positive RMS: Italy Captan 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance captan 22Oct2009 2009 doi:10.2903/j.efsa.2009.296r
+Captan 205-087-0 133-06-2 single chemical entity Component is identical to the substance Captan 205-087-0 133-06-2 2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione Captan C9H8Cl3NO2S ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Positive RMS: Italy Captan 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance captan 22Oct2009 2009 doi:10.2903/j.efsa.2009.296r
+Captan 205-087-0 133-06-2 single chemical entity Component is identical to the substance Captan 205-087-0 133-06-2 2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione Captan C9H8Cl3NO2S ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) fibroblast Not reported yes no data Negative RMS: Italy Captan 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance captan 22Oct2009 2009 doi:10.2903/j.efsa.2009.296r
+Captan 205-087-0 133-06-2 single chemical entity Component is identical to the substance Captan 205-087-0 133-06-2 2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione Captan C9H8Cl3NO2S ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Negative no information RMS: Italy Captan 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance captan 22Oct2009 2009 doi:10.2903/j.efsa.2009.296r
+Captan 205-087-0 133-06-2 single chemical entity Component is identical to the substance Captan 205-087-0 133-06-2 2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione Captan C9H8Cl3NO2S ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Positive no information RMS: Italy Captan 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance captan 22Oct2009 2009 doi:10.2903/j.efsa.2009.296r
+Captan 205-087-0 133-06-2 single chemical entity Component is identical to the substance Captan 205-087-0 133-06-2 2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione Captan C9H8Cl3NO2S ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes without Positive RMS: Italy Captan 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance captan 22Oct2009 2009 doi:10.2903/j.efsa.2009.296r
+Captan 205-087-0 133-06-2 single chemical entity Component is identical to the substance Captan 205-087-0 133-06-2 2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione Captan C9H8Cl3NO2S ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes not applicable Negative indirect evidence-systemic toxicity RMS: Italy Captan 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance captan 22Oct2009 2009 doi:10.2903/j.efsa.2009.296r
+Captan 205-087-0 133-06-2 single chemical entity Component is identical to the substance Captan 205-087-0 133-06-2 2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione Captan C9H8Cl3NO2S ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 72.0000000000 h yes not applicable Negative indirect evidence-systemic toxicity RMS: Italy Captan 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance captan 22Oct2009 2009 doi:10.2903/j.efsa.2009.296r
+Captan 205-087-0 133-06-2 single chemical entity Component is identical to the substance Captan 205-087-0 133-06-2 2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione Captan C9H8Cl3NO2S ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 48.0000000000 h yes not applicable Negative indirect evidence-systemic toxicity RMS: Italy Captan 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance captan 22Oct2009 2009 doi:10.2903/j.efsa.2009.296r
+Captan 205-087-0 133-06-2 single chemical entity Component is identical to the substance Captan 205-087-0 133-06-2 2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione Captan C9H8Cl3NO2S ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2 organic compound Other Other gene mutation mouse spot test in vivo According to OECD Guideline 484 (Genetic Toxicology: Mouse Spot Test) No Acceptable House mouse (as animal) C57BL Female oral: feed 4.0000000000 D yes not applicable Negative RMS: Italy Captan 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance captan 22Oct2009 2009 doi:10.2903/j.efsa.2009.296r
+Captan 205-087-0 133-06-2 single chemical entity Component is identical to the substance Captan 205-087-0 133-06-2 2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione Captan C9H8Cl3NO2S ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Crj:CD(SD) 6 Male oral: gavage 5.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Italy Captan 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance captan 22Oct2009 2009 doi:10.2903/j.efsa.2009.296r
+Captan 205-087-0 133-06-2 single chemical entity Component is identical to the substance Captan 205-087-0 133-06-2 2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione Captan C9H8Cl3NO2S ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2 organic compound Other Other chromosome aberration mammalian germ cell cytogenetic assay in vivo Equivalent or similar to OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test) Yes Acceptable House mouse (as animal) Not reported 5 Male oral: gavage 6.0000000000 h yes, concurrent vehicle not applicable Positive RMS: Italy Captan 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance captan 22Oct2009 2009 doi:10.2903/j.efsa.2009.296r
+Captan 205-087-0 133-06-2 single chemical entity Component is identical to the substance Captan 205-087-0 133-06-2 2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione Captan C9H8Cl3NO2S ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) Not reported No data oral: gavage 6.0000000000 h yes, concurrent vehicle not applicable Positive RMS: Italy Captan 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance captan 22Oct2009 2009 doi:10.2903/j.efsa.2009.296r
+Captan 205-087-0 133-06-2 single chemical entity Component is identical to the substance Captan 205-087-0 133-06-2 2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione Captan C9H8Cl3NO2S ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Not reported 5 No data oral: gavage 6.0000000000 h yes, concurrent vehicle not applicable Positive no evidence RMS: Italy Captan 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance captan 22Oct2009 2009 doi:10.2903/j.efsa.2009.296r
+Captan 205-087-0 133-06-2 single chemical entity Component is identical to the substance Captan 205-087-0 133-06-2 2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione Captan C9H8Cl3NO2S ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) Swiss No data intraperitoneal 12.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Italy Captan 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance captan 22Oct2009 2009 doi:10.2903/j.efsa.2009.296r
+Captan 205-087-0 133-06-2 single chemical entity Component is identical to the substance Captan 205-087-0 133-06-2 2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione Captan C9H8Cl3NO2S ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) Swiss No data intraperitoneal 6.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Italy Captan 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance captan 22Oct2009 2009 doi:10.2903/j.efsa.2009.296r
+Captan 205-087-0 133-06-2 single chemical entity Component is identical to the substance Captan 205-087-0 133-06-2 2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione Captan C9H8Cl3NO2S ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) Swiss No data intraperitoneal 54.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Italy Captan 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance captan 22Oct2009 2009 doi:10.2903/j.efsa.2009.296r
+Captan 205-087-0 133-06-2 single chemical entity Component is identical to the substance Captan 205-087-0 133-06-2 2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione Captan C9H8Cl3NO2S ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) Swiss No data intraperitoneal 30.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Italy Captan 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance captan 22Oct2009 2009 doi:10.2903/j.efsa.2009.296r
+Captan 205-087-0 133-06-2 single chemical entity Component is identical to the substance Captan 205-087-0 133-06-2 2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione Captan C9H8Cl3NO2S ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No data Acceptable House mouse (as animal) CD-1 Male oral: gavage 4.0000000000 h no data not applicable Negative RMS: Italy Captan 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance captan 22Oct2009 2009 doi:10.2903/j.efsa.2009.296r
+Captan 205-087-0 133-06-2 single chemical entity Component is identical to the substance Captan 205-087-0 133-06-2 2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione Captan C9H8Cl3NO2S ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No data Acceptable House mouse (as animal) C57BL 5 No data oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Italy Captan 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance captan 22Oct2009 2009 doi:10.2903/j.efsa.2009.296r
+Captan 205-087-0 133-06-2 single chemical entity Component is identical to the substance Captan 205-087-0 133-06-2 2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione Captan C9H8Cl3NO2S ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No data Acceptable House mouse (as animal) CD-1 Male oral: gavage 24.0000000000 h yes not applicable Negative RMS: Italy Captan 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance captan 22Oct2009 2009 doi:10.2903/j.efsa.2009.296r
+Captan 205-087-0 133-06-2 single chemical entity Component is identical to the substance Captan 205-087-0 133-06-2 2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione Captan C9H8Cl3NO2S ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No data Acceptable House mouse (as animal) C57BL Male oral: feed 24.0000000000 h yes not applicable Negative RMS: Italy Captan 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance captan 22Oct2009 2009 doi:10.2903/j.efsa.2009.296r
+Captan 205-087-0 133-06-2 single chemical entity Component is identical to the substance Captan 205-087-0 133-06-2 2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione Captan C9H8Cl3NO2S ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No data Acceptable House mouse (as animal) C57BL No data oral: gavage 24.0000000000 h yes not applicable Negative RMS: Italy Captan 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance captan 22Oct2009 2009 doi:10.2903/j.efsa.2009.296r
+Folpet 205-087-0 133-07-3 single chemical entity Component is part of a group but not included in the group assessment Captan 205-087-0 133-06-2 2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione Captan C9H8Cl3NO2S ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2 organic compound Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No data Acceptable House mouse (as animal) CD-1 Male oral: gavage 24.0000000000 h yes not applicable Negative RMS: Italy Folpet 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance folpet 31Aug2009 2009 doi:10.2903/j.efsa.2009.297r
+Folpet 205-087-0 133-07-3 single chemical entity Component is part of a group but not included in the group assessment Captan 205-087-0 133-06-2 2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione Captan C9H8Cl3NO2S ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2 organic compound Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No data Acceptable House mouse (as animal) CD-1 Male oral: gavage 4.0000000000 h no data not applicable Negative RMS: Italy Folpet 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance folpet 31Aug2009 2009 doi:10.2903/j.efsa.2009.297r
+Folpet 205-087-0 133-07-3 single chemical entity Component is part of a group but not included in the group assessment Captan 205-087-0 133-06-2 2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione Captan C9H8Cl3NO2S ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2 organic compound Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No data Acceptable House mouse (as animal) CD-1 No data oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Italy Folpet 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance folpet 31Aug2009 2009 doi:10.2903/j.efsa.2009.297r
+Folpet 205-087-0 133-07-3 single chemical entity Component is part of a group but not included in the group assessment Captan 205-087-0 133-06-2 2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione Captan C9H8Cl3NO2S ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2 organic compound Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No data Acceptable House mouse (as animal) C57BL Male oral: feed 24.0000000000 h yes not applicable Negative RMS: Italy Folpet 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance folpet 31Aug2009 2009 doi:10.2903/j.efsa.2009.297r
+Folpet 205-087-0 133-07-3 single chemical entity Component is part of a group but not included in the group assessment Captan 205-087-0 133-06-2 2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione Captan C9H8Cl3NO2S ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2 organic compound Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No data Acceptable House mouse (as animal) C57BL 5 No data oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Italy Folpet 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance folpet 31Aug2009 2009 doi:10.2903/j.efsa.2009.297r
+Folpet 205-087-0 133-07-3 single chemical entity Component is part of a group but not included in the group assessment Captan 205-087-0 133-06-2 2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione Captan C9H8Cl3NO2S ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2 organic compound Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No data Acceptable House mouse (as animal) C57BL No data oral: gavage 24.0000000000 h yes not applicable Negative RMS: Italy Folpet 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance folpet 31Aug2009 2009 doi:10.2903/j.efsa.2009.297r
+Captan 205-087-0 133-06-2 single chemical entity Component is identical to the substance Captan 205-087-0 133-06-2 2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione Captan C9H8Cl3NO2S ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2 organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Sprague-Dawley 5 Male oral: gavage 4.0000000000 h yes not applicable Negative RMS: Italy Captan 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance captan 22Oct2009 2009 doi:10.2903/j.efsa.2009.296r
+Captan 205-087-0 133-06-2 single chemical entity Component is identical to the substance Captan 205-087-0 133-06-2 2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione Captan C9H8Cl3NO2S ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2 organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Sprague-Dawley 5 Male oral: gavage 12.0000000000 h yes not applicable Negative RMS: Italy Captan 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance captan 22Oct2009 2009 doi:10.2903/j.efsa.2009.296r
+Captan 205-087-0 133-06-2 single chemical entity Component is identical to the substance Captan 205-087-0 133-06-2 2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione Captan C9H8Cl3NO2S ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Wistar 5 Male oral: unspecified 24.0000000000 h yes not applicable Negative no evidence RMS: Italy Captan 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance captan 22Oct2009 2009 doi:10.2903/j.efsa.2009.296r
+Captan 205-087-0 133-06-2 single chemical entity Component is identical to the substance Captan 205-087-0 133-06-2 2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione Captan C9H8Cl3NO2S ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2 organic compound Other Other chromosome aberration dominant lethal assay in vivo According to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) No Acceptable House mouse (as animal) Not reported 15 Male oral: unspecified 5.0000000000 D yes not applicable Negative RMS: Italy Captan 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance captan 22Oct2009 2009 doi:10.2903/j.efsa.2009.296r
+Captan 205-087-0 133-06-2 single chemical entity Component is identical to the substance Captan 205-087-0 133-06-2 2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione Captan C9H8Cl3NO2S ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2 organic compound Other Other chromosome aberration dominant lethal assay in vivo According to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) No Acceptable House mouse (as animal) Not reported 15 Male intraperitoneal yes not applicable Negative RMS: Italy Captan 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance captan 22Oct2009 2009 doi:10.2903/j.efsa.2009.296r
+Captan 205-087-0 133-06-2 single chemical entity Component is identical to the substance Captan 205-087-0 133-06-2 2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione Captan C9H8Cl3NO2S ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2 organic compound Other Other chromosome aberration dominant lethal assay in vivo According to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) No Acceptable Rat (as animal) Not reported 15 Male oral: gavage yes not applicable Ambiguous RMS: Italy Captan 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance captan 22Oct2009 2009 doi:10.2903/j.efsa.2009.296r
+Captan 205-087-0 133-06-2 single chemical entity Component is identical to the substance Captan 205-087-0 133-06-2 2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione Captan C9H8Cl3NO2S ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2 organic compound Other Other chromosome aberration dominant lethal assay in vivo According to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) No Acceptable Rat (as animal) Not reported 15 Male intraperitoneal 5.0000000000 D yes not applicable Negative RMS: Italy Captan 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance captan 22Oct2009 2009 doi:10.2903/j.efsa.2009.296r
+Captan 205-087-0 133-06-2 single chemical entity Component is identical to the substance Captan 205-087-0 133-06-2 2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione Captan C9H8Cl3NO2S ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2 organic compound Other Other chromosome aberration dominant lethal assay in vivo According to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) No Acceptable House mouse (as animal) Not reported 15 Male oral: gavage yes not applicable Ambiguous RMS: Italy Captan 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance captan 22Oct2009 2009 doi:10.2903/j.efsa.2009.296r
+Captan 205-087-0 133-06-2 single chemical entity Component is identical to the substance Captan 205-087-0 133-06-2 2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione Captan C9H8Cl3NO2S ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2 organic compound Other Other chromosome aberration dominant lethal assay in vivo According to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) No Acceptable House mouse (as animal) Swiss 10 Male intraperitoneal yes not applicable Negative RMS: Italy Captan 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance captan 22Oct2009 2009 doi:10.2903/j.efsa.2009.296r
+Captan 205-087-0 133-06-2 single chemical entity Component is identical to the substance Captan 205-087-0 133-06-2 2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione Captan C9H8Cl3NO2S ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2 organic compound Other Other chromosome aberration dominant lethal assay in vivo According to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) No Acceptable House mouse (as animal) Swiss 10 Male oral: gavage yes not applicable Negative RMS: Italy Captan 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance captan 22Oct2009 2009 doi:10.2903/j.efsa.2009.296r
+1,4-Dimethylnaphthalene 209-335-9 571-58-4 single chemical entity Component is identical to the substance 1,4-Dimethylnaphthalene 209-335-9 571-58-4 1,4-dimethylnaphthalene Not in list C12H12 Cc1ccc(C)c2ccccc12 InChI=1/C12H12/c1-9-7-8-10(2)12-6-4-3-5-11(9)12/h3-8H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: The Netherlands 1,4-Dimethylnaphthalene (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1,4-dimethylnaphthalene. 18Oct2013 2013 doi:10.2903/j.efsa.2013.3229
+1,4-Dimethylnaphthalene 209-335-9 571-58-4 single chemical entity Component is identical to the substance 1,4-Dimethylnaphthalene 209-335-9 571-58-4 1,4-dimethylnaphthalene Not in list C12H12 Cc1ccc(C)c2ccccc12 InChI=1/C12H12/c1-9-7-8-10(2)12-6-4-3-5-11(9)12/h3-8H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The Netherlands 1,4-Dimethylnaphthalene (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1,4-dimethylnaphthalene. 18Oct2013 2013 doi:10.2903/j.efsa.2013.3229
+1,4-Dimethylnaphthalene 209-335-9 571-58-4 single chemical entity Component is identical to the substance 1,4-Dimethylnaphthalene 209-335-9 571-58-4 1,4-dimethylnaphthalene Not in list C12H12 Cc1ccc(C)c2ccccc12 InChI=1/C12H12/c1-9-7-8-10(2)12-6-4-3-5-11(9)12/h3-8H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The Netherlands 1,4-Dimethylnaphthalene (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1,4-dimethylnaphthalene. 18Oct2013 2013 doi:10.2903/j.efsa.2013.3229
+1,4-Dimethylnaphthalene 209-335-9 571-58-4 single chemical entity Component is identical to the substance 1,4-Dimethylnaphthalene 209-335-9 571-58-4 1,4-dimethylnaphthalene Not in list C12H12 Cc1ccc(C)c2ccccc12 InChI=1/C12H12/c1-9-7-8-10(2)12-6-4-3-5-11(9)12/h3-8H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: The Netherlands 1,4-Dimethylnaphthalene (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1,4-dimethylnaphthalene. 18Oct2013 2013 doi:10.2903/j.efsa.2013.3229
+1,4-Dimethylnaphthalene 209-335-9 571-58-4 single chemical entity Component is identical to the substance 1,4-Dimethylnaphthalene 209-335-9 571-58-4 1,4-dimethylnaphthalene Not in list C12H12 Cc1ccc(C)c2ccccc12 InChI=1/C12H12/c1-9-7-8-10(2)12-6-4-3-5-11(9)12/h3-8H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The Netherlands 1,4-Dimethylnaphthalene (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1,4-dimethylnaphthalene. 18Oct2013 2013 doi:10.2903/j.efsa.2013.3229
+1,4-Dimethylnaphthalene 209-335-9 571-58-4 single chemical entity Component is identical to the substance 1,4-Dimethylnaphthalene 209-335-9 571-58-4 1,4-dimethylnaphthalene Not in list C12H12 Cc1ccc(C)c2ccccc12 InChI=1/C12H12/c1-9-7-8-10(2)12-6-4-3-5-11(9)12/h3-8H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The Netherlands 1,4-Dimethylnaphthalene (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1,4-dimethylnaphthalene. 18Oct2013 2013 doi:10.2903/j.efsa.2013.3229
+1,4-Dimethylnaphthalene 209-335-9 571-58-4 single chemical entity Component is identical to the substance 1,4-Dimethylnaphthalene 209-335-9 571-58-4 1,4-dimethylnaphthalene Not in list C12H12 Cc1ccc(C)c2ccccc12 InChI=1/C12H12/c1-9-7-8-10(2)12-6-4-3-5-11(9)12/h3-8H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The Netherlands 1,4-Dimethylnaphthalene (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1,4-dimethylnaphthalene. 18Oct2013 2013 doi:10.2903/j.efsa.2013.3229
+1,4-Dimethylnaphthalene 209-335-9 571-58-4 single chemical entity Component is identical to the substance 1,4-Dimethylnaphthalene 209-335-9 571-58-4 1,4-dimethylnaphthalene Not in list C12H12 Cc1ccc(C)c2ccccc12 InChI=1/C12H12/c1-9-7-8-10(2)12-6-4-3-5-11(9)12/h3-8H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The Netherlands 1,4-Dimethylnaphthalene (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1,4-dimethylnaphthalene. 18Oct2013 2013 doi:10.2903/j.efsa.2013.3229
+1,4-Dimethylnaphthalene 209-335-9 571-58-4 single chemical entity Component is identical to the substance 1,4-Dimethylnaphthalene 209-335-9 571-58-4 1,4-dimethylnaphthalene Not in list C12H12 Cc1ccc(C)c2ccccc12 InChI=1/C12H12/c1-9-7-8-10(2)12-6-4-3-5-11(9)12/h3-8H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The Netherlands 1,4-Dimethylnaphthalene (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1,4-dimethylnaphthalene. 18Oct2013 2013 doi:10.2903/j.efsa.2013.3229
+1,4-Dimethylnaphthalene 209-335-9 571-58-4 single chemical entity Component is identical to the substance 1,4-Dimethylnaphthalene 209-335-9 571-58-4 1,4-dimethylnaphthalene Not in list C12H12 Cc1ccc(C)c2ccccc12 InChI=1/C12H12/c1-9-7-8-10(2)12-6-4-3-5-11(9)12/h3-8H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The Netherlands 1,4-Dimethylnaphthalene (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1,4-dimethylnaphthalene. 18Oct2013 2013 doi:10.2903/j.efsa.2013.3229
+1,4-Dimethylnaphthalene 209-335-9 571-58-4 single chemical entity Component is identical to the substance 1,4-Dimethylnaphthalene 209-335-9 571-58-4 1,4-dimethylnaphthalene Not in list C12H12 Cc1ccc(C)c2ccccc12 InChI=1/C12H12/c1-9-7-8-10(2)12-6-4-3-5-11(9)12/h3-8H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The Netherlands 1,4-Dimethylnaphthalene (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1,4-dimethylnaphthalene. 18Oct2013 2013 doi:10.2903/j.efsa.2013.3229
+1,4-Dimethylnaphthalene 209-335-9 571-58-4 single chemical entity Component is identical to the substance 1,4-Dimethylnaphthalene 209-335-9 571-58-4 1,4-dimethylnaphthalene Not in list C12H12 Cc1ccc(C)c2ccccc12 InChI=1/C12H12/c1-9-7-8-10(2)12-6-4-3-5-11(9)12/h3-8H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The Netherlands 1,4-Dimethylnaphthalene (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1,4-dimethylnaphthalene. 18Oct2013 2013 doi:10.2903/j.efsa.2013.3229
+1,4-Dimethylnaphthalene 209-335-9 571-58-4 single chemical entity Component is identical to the substance 1,4-Dimethylnaphthalene 209-335-9 571-58-4 1,4-dimethylnaphthalene Not in list C12H12 Cc1ccc(C)c2ccccc12 InChI=1/C12H12/c1-9-7-8-10(2)12-6-4-3-5-11(9)12/h3-8H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The Netherlands 1,4-Dimethylnaphthalene (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1,4-dimethylnaphthalene. 18Oct2013 2013 doi:10.2903/j.efsa.2013.3229
+1,4-Dimethylnaphthalene 209-335-9 571-58-4 single chemical entity Component is identical to the substance 1,4-Dimethylnaphthalene 209-335-9 571-58-4 1,4-dimethylnaphthalene Not in list C12H12 Cc1ccc(C)c2ccccc12 InChI=1/C12H12/c1-9-7-8-10(2)12-6-4-3-5-11(9)12/h3-8H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The Netherlands 1,4-Dimethylnaphthalene (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1,4-dimethylnaphthalene. 18Oct2013 2013 doi:10.2903/j.efsa.2013.3229
+1,4-Dimethylnaphthalene 209-335-9 571-58-4 single chemical entity Component is identical to the substance 1,4-Dimethylnaphthalene 209-335-9 571-58-4 1,4-dimethylnaphthalene Not in list C12H12 Cc1ccc(C)c2ccccc12 InChI=1/C12H12/c1-9-7-8-10(2)12-6-4-3-5-11(9)12/h3-8H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The Netherlands 1,4-Dimethylnaphthalene (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1,4-dimethylnaphthalene. 18Oct2013 2013 doi:10.2903/j.efsa.2013.3229
+1,4-Dimethylnaphthalene 209-335-9 571-58-4 single chemical entity Component is identical to the substance 1,4-Dimethylnaphthalene 209-335-9 571-58-4 1,4-dimethylnaphthalene Not in list C12H12 Cc1ccc(C)c2ccccc12 InChI=1/C12H12/c1-9-7-8-10(2)12-6-4-3-5-11(9)12/h3-8H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The Netherlands 1,4-Dimethylnaphthalene (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1,4-dimethylnaphthalene. 18Oct2013 2013 doi:10.2903/j.efsa.2013.3229
+1,4-Dimethylnaphthalene 209-335-9 571-58-4 single chemical entity Component is identical to the substance 1,4-Dimethylnaphthalene 209-335-9 571-58-4 1,4-dimethylnaphthalene Not in list C12H12 Cc1ccc(C)c2ccccc12 InChI=1/C12H12/c1-9-7-8-10(2)12-6-4-3-5-11(9)12/h3-8H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes with Negative RMS: The Netherlands 1,4-Dimethylnaphthalene (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1,4-dimethylnaphthalene. 18Oct2013 2013 doi:10.2903/j.efsa.2013.3229
+1,4-Dimethylnaphthalene 209-335-9 571-58-4 single chemical entity Component is identical to the substance 1,4-Dimethylnaphthalene 209-335-9 571-58-4 1,4-dimethylnaphthalene Not in list C12H12 Cc1ccc(C)c2ccccc12 InChI=1/C12H12/c1-9-7-8-10(2)12-6-4-3-5-11(9)12/h3-8H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The Netherlands 1,4-Dimethylnaphthalene (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1,4-dimethylnaphthalene. 18Oct2013 2013 doi:10.2903/j.efsa.2013.3229
+1,4-Dimethylnaphthalene 209-335-9 571-58-4 single chemical entity Component is identical to the substance 1,4-Dimethylnaphthalene 209-335-9 571-58-4 1,4-dimethylnaphthalene Not in list C12H12 Cc1ccc(C)c2ccccc12 InChI=1/C12H12/c1-9-7-8-10(2)12-6-4-3-5-11(9)12/h3-8H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes without Negative RMS: The Netherlands 1,4-Dimethylnaphthalene (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1,4-dimethylnaphthalene. 18Oct2013 2013 doi:10.2903/j.efsa.2013.3229
+1,4-Dimethylnaphthalene 209-335-9 571-58-4 single chemical entity Component is identical to the substance 1,4-Dimethylnaphthalene 209-335-9 571-58-4 1,4-dimethylnaphthalene Not in list C12H12 Cc1ccc(C)c2ccccc12 InChI=1/C12H12/c1-9-7-8-10(2)12-6-4-3-5-11(9)12/h3-8H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The Netherlands 1,4-Dimethylnaphthalene (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1,4-dimethylnaphthalene. 18Oct2013 2013 doi:10.2903/j.efsa.2013.3229
+1,4-Dimethylnaphthalene 209-335-9 571-58-4 single chemical entity Component is identical to the substance 1,4-Dimethylnaphthalene 209-335-9 571-58-4 1,4-dimethylnaphthalene Not in list C12H12 Cc1ccc(C)c2ccccc12 InChI=1/C12H12/c1-9-7-8-10(2)12-6-4-3-5-11(9)12/h3-8H,1-2H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data without Negative no information RMS: The Netherlands 1,4-Dimethylnaphthalene (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1,4-dimethylnaphthalene. 18Oct2013 2013 doi:10.2903/j.efsa.2013.3229
+1,4-Dimethylnaphthalene 209-335-9 571-58-4 single chemical entity Component is identical to the substance 1,4-Dimethylnaphthalene 209-335-9 571-58-4 1,4-dimethylnaphthalene Not in list C12H12 Cc1ccc(C)c2ccccc12 InChI=1/C12H12/c1-9-7-8-10(2)12-6-4-3-5-11(9)12/h3-8H,1-2H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data with Positive small colonies RMS: The Netherlands 1,4-Dimethylnaphthalene (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1,4-dimethylnaphthalene. 18Oct2013 2013 doi:10.2903/j.efsa.2013.3229
+1,4-Dimethylnaphthalene 209-335-9 571-58-4 single chemical entity Component is identical to the substance 1,4-Dimethylnaphthalene 209-335-9 571-58-4 1,4-dimethylnaphthalene Not in list C12H12 Cc1ccc(C)c2ccccc12 InChI=1/C12H12/c1-9-7-8-10(2)12-6-4-3-5-11(9)12/h3-8H,1-2H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data with Positive large colonies RMS: The Netherlands 1,4-Dimethylnaphthalene (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1,4-dimethylnaphthalene. 18Oct2013 2013 doi:10.2903/j.efsa.2013.3229
+1-Methylcyclopropene 3100-04-7 single chemical entity Component is identical to the substance 1-Methylcyclopropene 3100-04-7 1-methylcyclopropene 1-methylcyclopropene C4H6 CC1=CC1 InChI=1S/C4H6/c1-4-2-3-4/h2H,3H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The United Kingdom 1-Methylcyclopropene 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance 1-methylcyclopropene 12May2005 2005 doi:10.2903/j.efsa.2005.30r
+1-Methylcyclopropene 3100-04-7 single chemical entity Component is identical to the substance 1-Methylcyclopropene 3100-04-7 1-methylcyclopropene 1-methylcyclopropene C4H6 CC1=CC1 InChI=1S/C4H6/c1-4-2-3-4/h2H,3H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The United Kingdom 1-Methylcyclopropene 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance 1-methylcyclopropene 12May2005 2005 doi:10.2903/j.efsa.2005.30r
+1-Methylcyclopropene 3100-04-7 single chemical entity Component is identical to the substance 1-Methylcyclopropene 3100-04-7 1-methylcyclopropene 1-methylcyclopropene C4H6 CC1=CC1 InChI=1S/C4H6/c1-4-2-3-4/h2H,3H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The United Kingdom 1-Methylcyclopropene 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance 1-methylcyclopropene 12May2005 2005 doi:10.2903/j.efsa.2005.30r
+1-Methylcyclopropene 3100-04-7 single chemical entity Component is identical to the substance 1-Methylcyclopropene 3100-04-7 1-methylcyclopropene 1-methylcyclopropene C4H6 CC1=CC1 InChI=1S/C4H6/c1-4-2-3-4/h2H,3H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The United Kingdom 1-Methylcyclopropene 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance 1-methylcyclopropene 12May2005 2005 doi:10.2903/j.efsa.2005.30r
+1-Methylcyclopropene 3100-04-7 single chemical entity Component is identical to the substance 1-Methylcyclopropene 3100-04-7 1-methylcyclopropene 1-methylcyclopropene C4H6 CC1=CC1 InChI=1S/C4H6/c1-4-2-3-4/h2H,3H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The United Kingdom 1-Methylcyclopropene 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance 1-methylcyclopropene 12May2005 2005 doi:10.2903/j.efsa.2005.30r
+1-Methylcyclopropene 3100-04-7 single chemical entity Component is identical to the substance 1-Methylcyclopropene 3100-04-7 1-methylcyclopropene 1-methylcyclopropene C4H6 CC1=CC1 InChI=1S/C4H6/c1-4-2-3-4/h2H,3H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The United Kingdom 1-Methylcyclopropene 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance 1-methylcyclopropene 12May2005 2005 doi:10.2903/j.efsa.2005.30r
+1-Methylcyclopropene 3100-04-7 single chemical entity Component is identical to the substance 1-Methylcyclopropene 3100-04-7 1-methylcyclopropene 1-methylcyclopropene C4H6 CC1=CC1 InChI=1S/C4H6/c1-4-2-3-4/h2H,3H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes with Negative RMS: The United Kingdom 1-Methylcyclopropene 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance 1-methylcyclopropene 12May2005 2005 doi:10.2903/j.efsa.2005.30r
+1-Methylcyclopropene 3100-04-7 single chemical entity Component is identical to the substance 1-Methylcyclopropene 3100-04-7 1-methylcyclopropene 1-methylcyclopropene C4H6 CC1=CC1 InChI=1S/C4H6/c1-4-2-3-4/h2H,3H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes without Negative RMS: The United Kingdom 1-Methylcyclopropene 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance 1-methylcyclopropene 12May2005 2005 doi:10.2903/j.efsa.2005.30r
+1-Methylcyclopropene 3100-04-7 single chemical entity Component is identical to the substance 1-Methylcyclopropene 3100-04-7 1-methylcyclopropene 1-methylcyclopropene C4H6 CC1=CC1 InChI=1S/C4H6/c1-4-2-3-4/h2H,3H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The United Kingdom 1-Methylcyclopropene 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance 1-methylcyclopropene 12May2005 2005 doi:10.2903/j.efsa.2005.30r
+1-Methylcyclopropene 3100-04-7 single chemical entity Component is identical to the substance 1-Methylcyclopropene 3100-04-7 1-methylcyclopropene 1-methylcyclopropene C4H6 CC1=CC1 InChI=1S/C4H6/c1-4-2-3-4/h2H,3H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The United Kingdom 1-Methylcyclopropene 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance 1-methylcyclopropene 12May2005 2005 doi:10.2903/j.efsa.2005.30r
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) B6C3F1 7 Male intraperitoneal 24.0000000000 h yes not applicable Negative no evidence RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Geraniol 269-750-6 106-24-1 single chemical entity Component is part of a group assessment Geranyl acetate 203-341-5 105-87-3 [(2E)-3,7-dimethylocta-2,6-dienyl] acetate Not in list C12H20O2 CC(=CCCC(=CCOC(=O)C)C)C InChI=1S/C12H20O2/c1-10(2)6-5-7-11(3)8-9-14-12(4)13/h6,8H,5,7,9H2,1-4H3/b11-8+ organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) B6C3F1 6 Male intraperitoneal 24.0000000000 h yes not applicable Negative no evidence RMS: The United Kingdom Geraniol 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance geraniol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2915
+2-(1-Naphthyl)acetamide 201-704-2 86-86-2 single chemical entity Component is identical to the substance 2-(1-Naphthyl)acetamide 201-704-2 86-86-2 2-naphthalen-1-ylacetamide Not in list C12H11NO NC(=O)Cc1cccc2ccccc12 InChI=1/C12H11NO/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H2,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: France Naphthaleneacetamide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2-(1-naphthyl)acetamide (notified as 1-naphthylacetamide) 23Feb2011 2011 doi:10.2903/j.efsa.2011.2020
+2-(1-Naphthyl)acetamide 201-704-2 86-86-2 single chemical entity Component is identical to the substance 2-(1-Naphthyl)acetamide 201-704-2 86-86-2 2-naphthalen-1-ylacetamide Not in list C12H11NO NC(=O)Cc1cccc2ccccc12 InChI=1/C12H11NO/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H2,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Naphthaleneacetamide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2-(1-naphthyl)acetamide (notified as 1-naphthylacetamide) 23Feb2011 2011 doi:10.2903/j.efsa.2011.2020
+2-(1-Naphthyl)acetamide 201-704-2 86-86-2 single chemical entity Component is identical to the substance 2-(1-Naphthyl)acetamide 201-704-2 86-86-2 2-naphthalen-1-ylacetamide Not in list C12H11NO NC(=O)Cc1cccc2ccccc12 InChI=1/C12H11NO/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H2,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Naphthaleneacetamide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2-(1-naphthyl)acetamide (notified as 1-naphthylacetamide) 23Feb2011 2011 doi:10.2903/j.efsa.2011.2020
+2-(1-Naphthyl)acetamide 201-704-2 86-86-2 single chemical entity Component is identical to the substance 2-(1-Naphthyl)acetamide 201-704-2 86-86-2 2-naphthalen-1-ylacetamide Not in list C12H11NO NC(=O)Cc1cccc2ccccc12 InChI=1/C12H11NO/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H2,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Naphthaleneacetamide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2-(1-naphthyl)acetamide (notified as 1-naphthylacetamide) 23Feb2011 2011 doi:10.2903/j.efsa.2011.2020
+2-(1-Naphthyl)acetamide 201-704-2 86-86-2 single chemical entity Component is identical to the substance 2-(1-Naphthyl)acetamide 201-704-2 86-86-2 2-naphthalen-1-ylacetamide Not in list C12H11NO NC(=O)Cc1cccc2ccccc12 InChI=1/C12H11NO/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H2,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Naphthaleneacetamide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2-(1-naphthyl)acetamide (notified as 1-naphthylacetamide) 23Feb2011 2011 doi:10.2903/j.efsa.2011.2020
+2-(1-Naphthyl)acetamide 201-704-2 86-86-2 single chemical entity Component is identical to the substance 2-(1-Naphthyl)acetamide 201-704-2 86-86-2 2-naphthalen-1-ylacetamide Not in list C12H11NO NC(=O)Cc1cccc2ccccc12 InChI=1/C12H11NO/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H2,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: France Naphthaleneacetamide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2-(1-naphthyl)acetamide (notified as 1-naphthylacetamide) 23Feb2011 2011 doi:10.2903/j.efsa.2011.2020
+2-(1-Naphthyl)acetamide 201-704-2 86-86-2 single chemical entity Component is identical to the substance 2-(1-Naphthyl)acetamide 201-704-2 86-86-2 2-naphthalen-1-ylacetamide Not in list C12H11NO NC(=O)Cc1cccc2ccccc12 InChI=1/C12H11NO/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H2,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Naphthaleneacetamide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2-(1-naphthyl)acetamide (notified as 1-naphthylacetamide) 23Feb2011 2011 doi:10.2903/j.efsa.2011.2020
+2-(1-Naphthyl)acetamide 201-704-2 86-86-2 single chemical entity Component is identical to the substance 2-(1-Naphthyl)acetamide 201-704-2 86-86-2 2-naphthalen-1-ylacetamide Not in list C12H11NO NC(=O)Cc1cccc2ccccc12 InChI=1/C12H11NO/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H2,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Naphthaleneacetamide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2-(1-naphthyl)acetamide (notified as 1-naphthylacetamide) 23Feb2011 2011 doi:10.2903/j.efsa.2011.2020
+2-(1-Naphthyl)acetamide 201-704-2 86-86-2 single chemical entity Component is identical to the substance 2-(1-Naphthyl)acetamide 201-704-2 86-86-2 2-naphthalen-1-ylacetamide Not in list C12H11NO NC(=O)Cc1cccc2ccccc12 InChI=1/C12H11NO/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H2,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Naphthaleneacetamide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2-(1-naphthyl)acetamide (notified as 1-naphthylacetamide) 23Feb2011 2011 doi:10.2903/j.efsa.2011.2020
+2-(1-Naphthyl)acetamide 201-704-2 86-86-2 single chemical entity Component is identical to the substance 2-(1-Naphthyl)acetamide 201-704-2 86-86-2 2-naphthalen-1-ylacetamide Not in list C12H11NO NC(=O)Cc1cccc2ccccc12 InChI=1/C12H11NO/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H2,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Naphthaleneacetamide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2-(1-naphthyl)acetamide (notified as 1-naphthylacetamide) 23Feb2011 2011 doi:10.2903/j.efsa.2011.2020
+1-Naphthylacetic acid 201-705-8 86-87-3 single chemical entity Component is identical to the substance 1-Naphthylacetic acid 201-705-8 86-87-3 1-2-naphthalen-1-ylacetic acid 1-naphthylacetic acid C12H10O2 OC(=O)Cc1cccc2ccccc12 InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Naphtaleneacetic acid 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid 23Feb2011 2011 doi:10.2903/j.efsa.2011.2019
+1-Naphthylacetic acid 201-705-8 86-87-3 single chemical entity Component is identical to the substance 1-Naphthylacetic acid 201-705-8 86-87-3 1-2-naphthalen-1-ylacetic acid 1-naphthylacetic acid C12H10O2 OC(=O)Cc1cccc2ccccc12 InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Naphtaleneacetic acid 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid 23Feb2011 2011 doi:10.2903/j.efsa.2011.2019
+1-Naphthylacetic acid 201-705-8 86-87-3 single chemical entity Component is identical to the substance 1-Naphthylacetic acid 201-705-8 86-87-3 1-2-naphthalen-1-ylacetic acid 1-naphthylacetic acid C12H10O2 OC(=O)Cc1cccc2ccccc12 InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Naphtaleneacetic acid 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid 23Feb2011 2011 doi:10.2903/j.efsa.2011.2019
+1-Naphthylacetic acid 201-705-8 86-87-3 single chemical entity Component is identical to the substance 1-Naphthylacetic acid 201-705-8 86-87-3 1-2-naphthalen-1-ylacetic acid 1-naphthylacetic acid C12H10O2 OC(=O)Cc1cccc2ccccc12 InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: France Naphtaleneacetic acid 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid 23Feb2011 2011 doi:10.2903/j.efsa.2011.2019
+1-Naphthylacetic acid 201-705-8 86-87-3 single chemical entity Component is identical to the substance 1-Naphthylacetic acid 201-705-8 86-87-3 1-2-naphthalen-1-ylacetic acid 1-naphthylacetic acid C12H10O2 OC(=O)Cc1cccc2ccccc12 InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Naphtaleneacetic acid 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid 23Feb2011 2011 doi:10.2903/j.efsa.2011.2019
+1-Naphthylacetic acid 201-705-8 86-87-3 single chemical entity Component is identical to the substance 1-Naphthylacetic acid 201-705-8 86-87-3 1-2-naphthalen-1-ylacetic acid 1-naphthylacetic acid C12H10O2 OC(=O)Cc1cccc2ccccc12 InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Naphtaleneacetic acid 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid 23Feb2011 2011 doi:10.2903/j.efsa.2011.2019
+1-Naphthylacetic acid 201-705-8 86-87-3 single chemical entity Component is identical to the substance 1-Naphthylacetic acid 201-705-8 86-87-3 1-2-naphthalen-1-ylacetic acid 1-naphthylacetic acid C12H10O2 OC(=O)Cc1cccc2ccccc12 InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: France Naphtaleneacetic acid 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid 23Feb2011 2011 doi:10.2903/j.efsa.2011.2019
+1-Naphthylacetic acid 201-705-8 86-87-3 single chemical entity Component is identical to the substance 1-Naphthylacetic acid 201-705-8 86-87-3 1-2-naphthalen-1-ylacetic acid 1-naphthylacetic acid C12H10O2 OC(=O)Cc1cccc2ccccc12 InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Naphtaleneacetic acid 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid 23Feb2011 2011 doi:10.2903/j.efsa.2011.2019
+1-Naphthylacetic acid 201-705-8 86-87-3 single chemical entity Component is identical to the substance 1-Naphthylacetic acid 201-705-8 86-87-3 1-2-naphthalen-1-ylacetic acid 1-naphthylacetic acid C12H10O2 OC(=O)Cc1cccc2ccccc12 InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Naphtaleneacetic acid 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid 23Feb2011 2011 doi:10.2903/j.efsa.2011.2019
+1-Naphthylacetic acid 201-705-8 86-87-3 single chemical entity Component is identical to the substance 1-Naphthylacetic acid 201-705-8 86-87-3 1-2-naphthalen-1-ylacetic acid 1-naphthylacetic acid C12H10O2 OC(=O)Cc1cccc2ccccc12 InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Naphtaleneacetic acid 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid 23Feb2011 2011 doi:10.2903/j.efsa.2011.2019
+1-Naphthylacetic acid 201-705-8 86-87-3 single chemical entity Component is identical to the substance 1-Naphthylacetic acid 201-705-8 86-87-3 1-2-naphthalen-1-ylacetic acid 1-naphthylacetic acid C12H10O2 OC(=O)Cc1cccc2ccccc12 InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle without Negative RMS: France Naphtaleneacetic acid 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid 23Feb2011 2011 doi:10.2903/j.efsa.2011.2019
+1-Naphthylacetic acid 201-705-8 86-87-3 single chemical entity Component is identical to the substance 1-Naphthylacetic acid 201-705-8 86-87-3 1-2-naphthalen-1-ylacetic acid 1-naphthylacetic acid C12H10O2 OC(=O)Cc1cccc2ccccc12 InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Naphtaleneacetic acid 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid 23Feb2011 2011 doi:10.2903/j.efsa.2011.2019
+1-Naphthylacetic acid 201-705-8 86-87-3 single chemical entity Component is identical to the substance 1-Naphthylacetic acid 201-705-8 86-87-3 1-2-naphthalen-1-ylacetic acid 1-naphthylacetic acid C12H10O2 OC(=O)Cc1cccc2ccccc12 InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Naphtaleneacetic acid 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid 23Feb2011 2011 doi:10.2903/j.efsa.2011.2019
+1-Naphthylacetic acid 201-705-8 86-87-3 single chemical entity Component is identical to the substance 1-Naphthylacetic acid 201-705-8 86-87-3 1-2-naphthalen-1-ylacetic acid 1-naphthylacetic acid C12H10O2 OC(=O)Cc1cccc2ccccc12 InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle without Negative RMS: France Naphtaleneacetic acid 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid 23Feb2011 2011 doi:10.2903/j.efsa.2011.2019
+1-Naphthylacetic acid 201-705-8 86-87-3 single chemical entity Component is identical to the substance 1-Naphthylacetic acid 201-705-8 86-87-3 1-2-naphthalen-1-ylacetic acid 1-naphthylacetic acid C12H10O2 OC(=O)Cc1cccc2ccccc12 InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle with Negative RMS: France Naphtaleneacetic acid 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid 23Feb2011 2011 doi:10.2903/j.efsa.2011.2019
+1-Naphthylacetic acid 201-705-8 86-87-3 single chemical entity Component is identical to the substance 1-Naphthylacetic acid 201-705-8 86-87-3 1-2-naphthalen-1-ylacetic acid 1-naphthylacetic acid C12H10O2 OC(=O)Cc1cccc2ccccc12 InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Naphtaleneacetic acid 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid 23Feb2011 2011 doi:10.2903/j.efsa.2011.2019
+1-Naphthylacetic acid 201-705-8 86-87-3 single chemical entity Component is identical to the substance 1-Naphthylacetic acid 201-705-8 86-87-3 1-2-naphthalen-1-ylacetic acid 1-naphthylacetic acid C12H10O2 OC(=O)Cc1cccc2ccccc12 InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Naphtaleneacetic acid 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid 23Feb2011 2011 doi:10.2903/j.efsa.2011.2019
+1-Naphthylacetic acid 201-705-8 86-87-3 single chemical entity Component is identical to the substance 1-Naphthylacetic acid 201-705-8 86-87-3 1-2-naphthalen-1-ylacetic acid 1-naphthylacetic acid C12H10O2 OC(=O)Cc1cccc2ccccc12 InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle with Negative RMS: France Naphtaleneacetic acid 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid 23Feb2011 2011 doi:10.2903/j.efsa.2011.2019
+1-Naphthylacetic acid 201-705-8 86-87-3 single chemical entity Component is identical to the substance 1-Naphthylacetic acid 201-705-8 86-87-3 1-2-naphthalen-1-ylacetic acid 1-naphthylacetic acid C12H10O2 OC(=O)Cc1cccc2ccccc12 InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Naphtaleneacetic acid 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid 23Feb2011 2011 doi:10.2903/j.efsa.2011.2019
+1-Naphthylacetic acid 201-705-8 86-87-3 single chemical entity Component is identical to the substance 1-Naphthylacetic acid 201-705-8 86-87-3 1-2-naphthalen-1-ylacetic acid 1-naphthylacetic acid C12H10O2 OC(=O)Cc1cccc2ccccc12 InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Naphtaleneacetic acid 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid 23Feb2011 2011 doi:10.2903/j.efsa.2011.2019
+1-Naphthylacetic acid 201-705-8 86-87-3 single chemical entity Component is identical to the substance 1-Naphthylacetic acid 201-705-8 86-87-3 1-2-naphthalen-1-ylacetic acid 1-naphthylacetic acid C12H10O2 OC(=O)Cc1cccc2ccccc12 InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Naphtaleneacetic acid 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid 23Feb2011 2011 doi:10.2903/j.efsa.2011.2019
+1-Naphthylacetic acid 201-705-8 86-87-3 single chemical entity Component is identical to the substance 1-Naphthylacetic acid 201-705-8 86-87-3 1-2-naphthalen-1-ylacetic acid 1-naphthylacetic acid C12H10O2 OC(=O)Cc1cccc2ccccc12 InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Naphtaleneacetic acid 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid 23Feb2011 2011 doi:10.2903/j.efsa.2011.2019
+1-Naphthylacetic acid 201-705-8 86-87-3 single chemical entity Component is a metabolite of the substance sodium 1-naphthylacetate 61-31-4 sodium;2-naphthalen-1-ylacetate Not in list C12H9NaO2 C1=CC=C2C(=C1)C=CC=C2CC(=O)[O-].[Na+] InChI=1S/C12H10O2.Na/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10;/h1-7H,8H2,(H,13,14);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Naphtaleneacetic acid 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid 23Feb2011 2011 doi:10.2903/j.efsa.2011.2019
+1-Naphthylacetic acid 201-705-8 86-87-3 single chemical entity Component is a metabolite of the substance sodium 1-naphthylacetate 61-31-4 sodium;2-naphthalen-1-ylacetate Not in list C12H9NaO2 C1=CC=C2C(=C1)C=CC=C2CC(=O)[O-].[Na+] InChI=1S/C12H10O2.Na/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10;/h1-7H,8H2,(H,13,14);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Naphtaleneacetic acid 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid 23Feb2011 2011 doi:10.2903/j.efsa.2011.2019
+1-Naphthylacetic acid 201-705-8 86-87-3 single chemical entity Component is a metabolite of the substance sodium 1-naphthylacetate 61-31-4 sodium;2-naphthalen-1-ylacetate Not in list C12H9NaO2 C1=CC=C2C(=C1)C=CC=C2CC(=O)[O-].[Na+] InChI=1S/C12H10O2.Na/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10;/h1-7H,8H2,(H,13,14);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: France Naphtaleneacetic acid 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid 23Feb2011 2011 doi:10.2903/j.efsa.2011.2019
+1-Naphthylacetic acid 201-705-8 86-87-3 single chemical entity Component is a metabolite of the substance sodium 1-naphthylacetate 61-31-4 sodium;2-naphthalen-1-ylacetate Not in list C12H9NaO2 C1=CC=C2C(=C1)C=CC=C2CC(=O)[O-].[Na+] InChI=1S/C12H10O2.Na/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10;/h1-7H,8H2,(H,13,14);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: France Naphtaleneacetic acid 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid 23Feb2011 2011 doi:10.2903/j.efsa.2011.2019
+1-Naphthylacetic acid 201-705-8 86-87-3 single chemical entity Component is a metabolite of the substance sodium 1-naphthylacetate 61-31-4 sodium;2-naphthalen-1-ylacetate Not in list C12H9NaO2 C1=CC=C2C(=C1)C=CC=C2CC(=O)[O-].[Na+] InChI=1S/C12H10O2.Na/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10;/h1-7H,8H2,(H,13,14);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Naphtaleneacetic acid 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid 23Feb2011 2011 doi:10.2903/j.efsa.2011.2019
+1-Naphthylacetic acid 201-705-8 86-87-3 single chemical entity Component is a metabolite of the substance sodium 1-naphthylacetate 61-31-4 sodium;2-naphthalen-1-ylacetate Not in list C12H9NaO2 C1=CC=C2C(=C1)C=CC=C2CC(=O)[O-].[Na+] InChI=1S/C12H10O2.Na/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10;/h1-7H,8H2,(H,13,14);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Naphtaleneacetic acid 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid 23Feb2011 2011 doi:10.2903/j.efsa.2011.2019
+1-Naphthylacetic acid 201-705-8 86-87-3 single chemical entity Component is a metabolite of the substance sodium 1-naphthylacetate 61-31-4 sodium;2-naphthalen-1-ylacetate Not in list C12H9NaO2 C1=CC=C2C(=C1)C=CC=C2CC(=O)[O-].[Na+] InChI=1S/C12H10O2.Na/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10;/h1-7H,8H2,(H,13,14);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Naphtaleneacetic acid 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid 23Feb2011 2011 doi:10.2903/j.efsa.2011.2019
+1-Naphthylacetic acid 201-705-8 86-87-3 single chemical entity Component is a metabolite of the substance sodium 1-naphthylacetate 61-31-4 sodium;2-naphthalen-1-ylacetate Not in list C12H9NaO2 C1=CC=C2C(=C1)C=CC=C2CC(=O)[O-].[Na+] InChI=1S/C12H10O2.Na/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10;/h1-7H,8H2,(H,13,14);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Naphtaleneacetic acid 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid 23Feb2011 2011 doi:10.2903/j.efsa.2011.2019
+1-Naphthylacetic acid 201-705-8 86-87-3 single chemical entity Component is a metabolite of the substance sodium 1-naphthylacetate 61-31-4 sodium;2-naphthalen-1-ylacetate Not in list C12H9NaO2 C1=CC=C2C(=C1)C=CC=C2CC(=O)[O-].[Na+] InChI=1S/C12H10O2.Na/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10;/h1-7H,8H2,(H,13,14);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Naphtaleneacetic acid 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid 23Feb2011 2011 doi:10.2903/j.efsa.2011.2019
+1-Naphthylacetic acid 201-705-8 86-87-3 single chemical entity Component is a metabolite of the substance sodium 1-naphthylacetate 61-31-4 sodium;2-naphthalen-1-ylacetate Not in list C12H9NaO2 C1=CC=C2C(=C1)C=CC=C2CC(=O)[O-].[Na+] InChI=1S/C12H10O2.Na/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10;/h1-7H,8H2,(H,13,14);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Naphtaleneacetic acid 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid 23Feb2011 2011 doi:10.2903/j.efsa.2011.2019
+1-Naphthylacetic acid 201-705-8 86-87-3 single chemical entity Component is identical to the substance 1-Naphthylacetic acid 201-705-8 86-87-3 1-2-naphthalen-1-ylacetic acid 1-naphthylacetic acid C12H10O2 OC(=O)Cc1cccc2ccccc12 InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14) organic compound Other Other gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) (k12)p3478 Not reported no data without Negative RMS: France Naphtaleneacetic acid 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid 23Feb2011 2011 doi:10.2903/j.efsa.2011.2019
+1-Naphthylacetic acid 201-705-8 86-87-3 single chemical entity Component is identical to the substance 1-Naphthylacetic acid 201-705-8 86-87-3 1-2-naphthalen-1-ylacetic acid 1-naphthylacetic acid C12H10O2 OC(=O)Cc1cccc2ccccc12 InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14) organic compound Other Other gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) W3110 Not reported no data without Negative RMS: France Naphtaleneacetic acid 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid 23Feb2011 2011 doi:10.2903/j.efsa.2011.2019
+1-Naphthylacetic acid 201-705-8 86-87-3 single chemical entity Component is identical to the substance 1-Naphthylacetic acid 201-705-8 86-87-3 1-2-naphthalen-1-ylacetic acid 1-naphthylacetic acid C12H10O2 OC(=O)Cc1cccc2ccccc12 InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14) organic compound Other Other gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) (k12)p3478 Not reported no data with Negative RMS: France Naphtaleneacetic acid 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid 23Feb2011 2011 doi:10.2903/j.efsa.2011.2019
+1-Naphthylacetic acid 201-705-8 86-87-3 single chemical entity Component is identical to the substance 1-Naphthylacetic acid 201-705-8 86-87-3 1-2-naphthalen-1-ylacetic acid 1-naphthylacetic acid C12H10O2 OC(=O)Cc1cccc2ccccc12 InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14) organic compound Other Other gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) W3110 Not reported no data with Negative RMS: France Naphtaleneacetic acid 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid 23Feb2011 2011 doi:10.2903/j.efsa.2011.2019
+2,4-D 202-361-1 94-75-7 single chemical entity Component is identical to the substance 2,4-D 202-361-1 94-75-7 (2,4-dichlorophenoxy)acetic acid 2,4-D C8H6Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCC(=O)O InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-D 202-361-1 94-75-7 single chemical entity Component is identical to the substance 2,4-D 202-361-1 94-75-7 (2,4-dichlorophenoxy)acetic acid 2,4-D C8H6Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCC(=O)O InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-D 202-361-1 94-75-7 single chemical entity Component is identical to the substance 2,4-D 202-361-1 94-75-7 (2,4-dichlorophenoxy)acetic acid 2,4-D C8H6Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCC(=O)O InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-D 202-361-1 94-75-7 single chemical entity Component is identical to the substance 2,4-D 202-361-1 94-75-7 (2,4-dichlorophenoxy)acetic acid 2,4-D C8H6Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCC(=O)O InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-D 202-361-1 94-75-7 single chemical entity Component is identical to the substance 2,4-D 202-361-1 94-75-7 (2,4-dichlorophenoxy)acetic acid 2,4-D C8H6Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCC(=O)O InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-D 202-361-1 94-75-7 single chemical entity Component is identical to the substance 2,4-D 202-361-1 94-75-7 (2,4-dichlorophenoxy)acetic acid 2,4-D C8H6Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCC(=O)O InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-D 202-361-1 94-75-7 single chemical entity Component is identical to the substance 2,4-D 202-361-1 94-75-7 (2,4-dichlorophenoxy)acetic acid 2,4-D C8H6Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCC(=O)O InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-D 202-361-1 94-75-7 single chemical entity Component is identical to the substance 2,4-D 202-361-1 94-75-7 (2,4-dichlorophenoxy)acetic acid 2,4-D C8H6Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCC(=O)O InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-D 202-361-1 94-75-7 single chemical entity Component is identical to the substance 2,4-D 202-361-1 94-75-7 (2,4-dichlorophenoxy)acetic acid 2,4-D C8H6Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCC(=O)O InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-D 202-361-1 94-75-7 single chemical entity Component is identical to the substance 2,4-D 202-361-1 94-75-7 (2,4-dichlorophenoxy)acetic acid 2,4-D C8H6Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCC(=O)O InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+8-Hydroxyquinoline 205-711-1 148-24-3 single chemical entity Component is identical to the substance 8-Hydroxyquinoline 205-711-1 148-24-3 Quinolin-8-ol Not in list C9H7NO C1=CC2=C(C(=C1)O)N=CC=C2 InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Spain 8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline 28Jan2011 2011 doi:10.2903/j.efsa.2011.1964
+8-Hydroxyquinoline 205-711-1 148-24-3 single chemical entity Component is identical to the substance 8-Hydroxyquinoline 205-711-1 148-24-3 Quinolin-8-ol Not in list C9H7NO C1=CC2=C(C(=C1)O)N=CC=C2 InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Spain 8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline 28Jan2011 2011 doi:10.2903/j.efsa.2011.1964
+8-Hydroxyquinoline 205-711-1 148-24-3 single chemical entity Component is identical to the substance 8-Hydroxyquinoline 205-711-1 148-24-3 Quinolin-8-ol Not in list C9H7NO C1=CC2=C(C(=C1)O)N=CC=C2 InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Spain 8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline 28Jan2011 2011 doi:10.2903/j.efsa.2011.1964
+8-Hydroxyquinoline 205-711-1 148-24-3 single chemical entity Component is identical to the substance 8-Hydroxyquinoline 205-711-1 148-24-3 Quinolin-8-ol Not in list C9H7NO C1=CC2=C(C(=C1)O)N=CC=C2 InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Spain 8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline 28Jan2011 2011 doi:10.2903/j.efsa.2011.1964
+8-Hydroxyquinoline 205-711-1 148-24-3 single chemical entity Component is identical to the substance 8-Hydroxyquinoline 205-711-1 148-24-3 Quinolin-8-ol Not in list C9H7NO C1=CC2=C(C(=C1)O)N=CC=C2 InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Spain 8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline 28Jan2011 2011 doi:10.2903/j.efsa.2011.1964
+8-Hydroxyquinoline 205-711-1 148-24-3 single chemical entity Component is identical to the substance 8-Hydroxyquinoline 205-711-1 148-24-3 Quinolin-8-ol Not in list C9H7NO C1=CC2=C(C(=C1)O)N=CC=C2 InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Spain 8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline 28Jan2011 2011 doi:10.2903/j.efsa.2011.1964
+8-Hydroxyquinoline 205-711-1 148-24-3 single chemical entity Component is identical to the substance 8-Hydroxyquinoline 205-711-1 148-24-3 Quinolin-8-ol Not in list C9H7NO C1=CC2=C(C(=C1)O)N=CC=C2 InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Spain 8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline 28Jan2011 2011 doi:10.2903/j.efsa.2011.1964
+8-Hydroxyquinoline 205-711-1 148-24-3 single chemical entity Component is identical to the substance 8-Hydroxyquinoline 205-711-1 148-24-3 Quinolin-8-ol Not in list C9H7NO C1=CC2=C(C(=C1)O)N=CC=C2 InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Spain 8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline 28Jan2011 2011 doi:10.2903/j.efsa.2011.1964
+8-Hydroxyquinoline 205-711-1 148-24-3 single chemical entity Component is identical to the substance 8-Hydroxyquinoline 205-711-1 148-24-3 Quinolin-8-ol Not in list C9H7NO C1=CC2=C(C(=C1)O)N=CC=C2 InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Spain 8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline 28Jan2011 2011 doi:10.2903/j.efsa.2011.1964
+8-Hydroxyquinoline 205-711-1 148-24-3 single chemical entity Component is identical to the substance 8-Hydroxyquinoline 205-711-1 148-24-3 Quinolin-8-ol Not in list C9H7NO C1=CC2=C(C(=C1)O)N=CC=C2 InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Spain 8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline 28Jan2011 2011 doi:10.2903/j.efsa.2011.1964
+8-Hydroxyquinoline 205-711-1 148-24-3 single chemical entity Component is identical to the substance 8-Hydroxyquinoline 205-711-1 148-24-3 Quinolin-8-ol Not in list C9H7NO C1=CC2=C(C(=C1)O)N=CC=C2 InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) B6C3F1 4 Male intraperitoneal 23.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Spain 8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline 28Jan2011 2011 doi:10.2903/j.efsa.2011.1964
+8-Hydroxyquinoline 205-711-1 148-24-3 single chemical entity Component is identical to the substance 8-Hydroxyquinoline 205-711-1 148-24-3 Quinolin-8-ol Not in list C9H7NO C1=CC2=C(C(=C1)O)N=CC=C2 InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) B6C3F1 4 Male intraperitoneal 42.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Spain 8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline 28Jan2011 2011 doi:10.2903/j.efsa.2011.1964
+Abamectin 71751-41-2 mixture or formulation Component is identical to the substance Abamectin 71751-41-2 (9Z,13Z,15Z)-6'-(butan-2-yl)-19,21b-dihydroxy-5',10,12,20-tetramethyl-1-oxo-3,4,5',6',8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2'-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a) C49H74O14 CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14- organic representative compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: The Netherlands Abamectin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi 29Jul2008 2008 doi:10.2903/j.efsa.2008.147r
+Abamectin 71751-41-2 mixture or formulation Component is identical to the substance Abamectin 71751-41-2 (9Z,13Z,15Z)-6'-(butan-2-yl)-19,21b-dihydroxy-5',10,12,20-tetramethyl-1-oxo-3,4,5',6',8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2'-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a) C49H74O14 CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14- organic representative compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The Netherlands Abamectin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi 29Jul2008 2008 doi:10.2903/j.efsa.2008.147r
+Abamectin 71751-41-2 mixture or formulation Component is identical to the substance Abamectin 71751-41-2 (9Z,13Z,15Z)-6'-(butan-2-yl)-19,21b-dihydroxy-5',10,12,20-tetramethyl-1-oxo-3,4,5',6',8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2'-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a) C49H74O14 CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14- organic representative compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The Netherlands Abamectin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi 29Jul2008 2008 doi:10.2903/j.efsa.2008.147r
+Abamectin 71751-41-2 mixture or formulation Component is identical to the substance Abamectin 71751-41-2 (9Z,13Z,15Z)-6'-(butan-2-yl)-19,21b-dihydroxy-5',10,12,20-tetramethyl-1-oxo-3,4,5',6',8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2'-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a) C49H74O14 CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14- organic representative compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The Netherlands Abamectin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi 29Jul2008 2008 doi:10.2903/j.efsa.2008.147r
+Abamectin 71751-41-2 mixture or formulation Component is identical to the substance Abamectin 71751-41-2 (9Z,13Z,15Z)-6'-(butan-2-yl)-19,21b-dihydroxy-5',10,12,20-tetramethyl-1-oxo-3,4,5',6',8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2'-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a) C49H74O14 CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14- organic representative compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes without Negative RMS: The Netherlands Abamectin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi 29Jul2008 2008 doi:10.2903/j.efsa.2008.147r
+Abamectin 71751-41-2 mixture or formulation Component is identical to the substance Abamectin 71751-41-2 (9Z,13Z,15Z)-6'-(butan-2-yl)-19,21b-dihydroxy-5',10,12,20-tetramethyl-1-oxo-3,4,5',6',8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2'-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a) C49H74O14 CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14- organic representative compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The Netherlands Abamectin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi 29Jul2008 2008 doi:10.2903/j.efsa.2008.147r
+Abamectin 71751-41-2 mixture or formulation Component is identical to the substance Abamectin 71751-41-2 (9Z,13Z,15Z)-6'-(butan-2-yl)-19,21b-dihydroxy-5',10,12,20-tetramethyl-1-oxo-3,4,5',6',8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2'-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a) C49H74O14 CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14- organic representative compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes with Negative RMS: The Netherlands Abamectin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi 29Jul2008 2008 doi:10.2903/j.efsa.2008.147r
+Abamectin 71751-41-2 mixture or formulation Component is identical to the substance Abamectin 71751-41-2 (9Z,13Z,15Z)-6'-(butan-2-yl)-19,21b-dihydroxy-5',10,12,20-tetramethyl-1-oxo-3,4,5',6',8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2'-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a) C49H74O14 CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14- organic representative compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The Netherlands Abamectin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi 29Jul2008 2008 doi:10.2903/j.efsa.2008.147r
+Abamectin 71751-41-2 mixture or formulation Component is identical to the substance Abamectin 71751-41-2 (9Z,13Z,15Z)-6'-(butan-2-yl)-19,21b-dihydroxy-5',10,12,20-tetramethyl-1-oxo-3,4,5',6',8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2'-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a) C49H74O14 CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14- organic representative compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The Netherlands Abamectin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi 29Jul2008 2008 doi:10.2903/j.efsa.2008.147r
+Abamectin 71751-41-2 mixture or formulation Component is identical to the substance Abamectin 71751-41-2 (9Z,13Z,15Z)-6'-(butan-2-yl)-19,21b-dihydroxy-5',10,12,20-tetramethyl-1-oxo-3,4,5',6',8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2'-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a) C49H74O14 CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14- organic representative compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The Netherlands Abamectin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi 29Jul2008 2008 doi:10.2903/j.efsa.2008.147r
+Abamectin 71751-41-2 mixture or formulation Component is identical to the substance Abamectin 71751-41-2 (9Z,13Z,15Z)-6'-(butan-2-yl)-19,21b-dihydroxy-5',10,12,20-tetramethyl-1-oxo-3,4,5',6',8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2'-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a) C49H74O14 CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14- organic representative compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The Netherlands Abamectin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi 29Jul2008 2008 doi:10.2903/j.efsa.2008.147r
+Abamectin 71751-41-2 mixture or formulation Component is identical to the substance Abamectin 71751-41-2 (9Z,13Z,15Z)-6'-(butan-2-yl)-19,21b-dihydroxy-5',10,12,20-tetramethyl-1-oxo-3,4,5',6',8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2'-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a) C49H74O14 CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14- organic representative compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: The Netherlands Abamectin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi 29Jul2008 2008 doi:10.2903/j.efsa.2008.147r
+Abamectin 71751-41-2 single chemical entity Component is a metabolite of the substance [8,9-Z]-isomer of avermectin B1a {(2aZ,4Z,5'S,6R,6'R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6'-[(2S)-butan-2-yl]-19,19b-dihydroxy-5',6,7,18-tetramethyl-16-oxo-5',6,6',9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2'-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside Avermectin B1a, delta-8,9 isomer C47H70O14 CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The Netherlands Abamectin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi 29Jul2008 2008 doi:10.2903/j.efsa.2008.147r
+Abamectin 71751-41-2 single chemical entity Component is a metabolite of the substance [8,9-Z]-isomer of avermectin B1a {(2aZ,4Z,5'S,6R,6'R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6'-[(2S)-butan-2-yl]-19,19b-dihydroxy-5',6,7,18-tetramethyl-16-oxo-5',6,6',9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2'-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside Avermectin B1a, delta-8,9 isomer C47H70O14 CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: The Netherlands Abamectin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi 29Jul2008 2008 doi:10.2903/j.efsa.2008.147r
+Abamectin 71751-41-2 single chemical entity Component is a metabolite of the substance [8,9-Z]-isomer of avermectin B1a {(2aZ,4Z,5'S,6R,6'R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6'-[(2S)-butan-2-yl]-19,19b-dihydroxy-5',6,7,18-tetramethyl-16-oxo-5',6,6',9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2'-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside Avermectin B1a, delta-8,9 isomer C47H70O14 CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes without Negative RMS: The Netherlands Abamectin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi 29Jul2008 2008 doi:10.2903/j.efsa.2008.147r
+Abamectin 71751-41-2 single chemical entity Component is a metabolite of the substance [8,9-Z]-isomer of avermectin B1a {(2aZ,4Z,5'S,6R,6'R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6'-[(2S)-butan-2-yl]-19,19b-dihydroxy-5',6,7,18-tetramethyl-16-oxo-5',6,6',9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2'-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside Avermectin B1a, delta-8,9 isomer C47H70O14 CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: The Netherlands Abamectin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi 29Jul2008 2008 doi:10.2903/j.efsa.2008.147r
+Abamectin 71751-41-2 single chemical entity Component is a metabolite of the substance [8,9-Z]-isomer of avermectin B1a {(2aZ,4Z,5'S,6R,6'R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6'-[(2S)-butan-2-yl]-19,19b-dihydroxy-5',6,7,18-tetramethyl-16-oxo-5',6,6',9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2'-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside Avermectin B1a, delta-8,9 isomer C47H70O14 CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The Netherlands Abamectin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi 29Jul2008 2008 doi:10.2903/j.efsa.2008.147r
+Abamectin 71751-41-2 single chemical entity Component is a metabolite of the substance [8,9-Z]-isomer of avermectin B1a {(2aZ,4Z,5'S,6R,6'R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6'-[(2S)-butan-2-yl]-19,19b-dihydroxy-5',6,7,18-tetramethyl-16-oxo-5',6,6',9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2'-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside Avermectin B1a, delta-8,9 isomer C47H70O14 CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 Not reported yes without Negative RMS: The Netherlands Abamectin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi 29Jul2008 2008 doi:10.2903/j.efsa.2008.147r
+Abamectin 71751-41-2 single chemical entity Component is a metabolite of the substance [8,9-Z]-isomer of avermectin B1a {(2aZ,4Z,5'S,6R,6'R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6'-[(2S)-butan-2-yl]-19,19b-dihydroxy-5',6,7,18-tetramethyl-16-oxo-5',6,6',9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2'-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside Avermectin B1a, delta-8,9 isomer C47H70O14 CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 Not reported yes with Negative RMS: The Netherlands Abamectin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi 29Jul2008 2008 doi:10.2903/j.efsa.2008.147r
+Abamectin 71751-41-2 single chemical entity Component is a metabolite of the substance [8,9-Z]-isomer of avermectin B1a {(2aZ,4Z,5'S,6R,6'R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6'-[(2S)-butan-2-yl]-19,19b-dihydroxy-5',6,7,18-tetramethyl-16-oxo-5',6,6',9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2'-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside Avermectin B1a, delta-8,9 isomer C47H70O14 CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes without Negative RMS: The Netherlands Abamectin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi 29Jul2008 2008 doi:10.2903/j.efsa.2008.147r
+Abamectin 71751-41-2 single chemical entity Component is a metabolite of the substance [8,9-Z]-isomer of avermectin B1a {(2aZ,4Z,5'S,6R,6'R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6'-[(2S)-butan-2-yl]-19,19b-dihydroxy-5',6,7,18-tetramethyl-16-oxo-5',6,6',9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2'-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside Avermectin B1a, delta-8,9 isomer C47H70O14 CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The Netherlands Abamectin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi 29Jul2008 2008 doi:10.2903/j.efsa.2008.147r
+Abamectin 71751-41-2 single chemical entity Component is a metabolite of the substance [8,9-Z]-isomer of avermectin B1a {(2aZ,4Z,5'S,6R,6'R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6'-[(2S)-butan-2-yl]-19,19b-dihydroxy-5',6,7,18-tetramethyl-16-oxo-5',6,6',9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2'-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside Avermectin B1a, delta-8,9 isomer C47H70O14 CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes with Negative RMS: The Netherlands Abamectin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi 29Jul2008 2008 doi:10.2903/j.efsa.2008.147r
+Abamectin 71751-41-2 single chemical entity Component is a metabolite of the substance [8,9-Z]-isomer of avermectin B1a {(2aZ,4Z,5'S,6R,6'R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6'-[(2S)-butan-2-yl]-19,19b-dihydroxy-5',6,7,18-tetramethyl-16-oxo-5',6,6',9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2'-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside Avermectin B1a, delta-8,9 isomer C47H70O14 CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes with Negative RMS: The Netherlands Abamectin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi 29Jul2008 2008 doi:10.2903/j.efsa.2008.147r
+Abamectin 71751-41-2 single chemical entity Component is a metabolite of the substance [8,9-Z]-isomer of avermectin B1a {(2aZ,4Z,5'S,6R,6'R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6'-[(2S)-butan-2-yl]-19,19b-dihydroxy-5',6,7,18-tetramethyl-16-oxo-5',6,6',9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2'-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside Avermectin B1a, delta-8,9 isomer C47H70O14 CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The Netherlands Abamectin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi 29Jul2008 2008 doi:10.2903/j.efsa.2008.147r
+Abamectin 71751-41-2 single chemical entity Component is a metabolite of the substance [8,9-Z]-isomer of avermectin B1a {(2aZ,4Z,5'S,6R,6'R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6'-[(2S)-butan-2-yl]-19,19b-dihydroxy-5',6,7,18-tetramethyl-16-oxo-5',6,6',9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2'-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside Avermectin B1a, delta-8,9 isomer C47H70O14 CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The Netherlands Abamectin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi 29Jul2008 2008 doi:10.2903/j.efsa.2008.147r
+Abamectin 71751-41-2 single chemical entity Component is a metabolite of the substance [8,9-Z]-isomer of avermectin B1a {(2aZ,4Z,5'S,6R,6'R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6'-[(2S)-butan-2-yl]-19,19b-dihydroxy-5',6,7,18-tetramethyl-16-oxo-5',6,6',9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2'-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside Avermectin B1a, delta-8,9 isomer C47H70O14 CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The Netherlands Abamectin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi 29Jul2008 2008 doi:10.2903/j.efsa.2008.147r
+Acequinocyl 57960-19-7 single chemical entity Component is identical to the substance Acequinocyl 57960-19-7 3-dodecyl-1,4-dioxo-1,4-dihydronaphthalen-2-yl acetate Acequinocyl C24H32O4 CC(=O)OC2=C(CCCCCCCCCCCC)C(=O)c1ccccc1C2=O InChI=1S/C24H32O4/c1-3-4-5-6-7-8-9-10-11-12-17-21-22(26)19-15-13-14-16-20(19)23(27)24(21)28-18(2)25/h13-16H,3-12,17H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The Netherlands Acequinocyl (Revised version of September 2007) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl. 02May2013 2013 doi:10.2903/j.efsa.2013.3212
+Acequinocyl 57960-19-7 single chemical entity Component is identical to the substance Acequinocyl 57960-19-7 3-dodecyl-1,4-dioxo-1,4-dihydronaphthalen-2-yl acetate Acequinocyl C24H32O4 CC(=O)OC2=C(CCCCCCCCCCCC)C(=O)c1ccccc1C2=O InChI=1S/C24H32O4/c1-3-4-5-6-7-8-9-10-11-12-17-21-22(26)19-15-13-14-16-20(19)23(27)24(21)28-18(2)25/h13-16H,3-12,17H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The Netherlands Acequinocyl (Revised version of September 2007) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl. 02May2013 2013 doi:10.2903/j.efsa.2013.3212
+Acequinocyl 57960-19-7 single chemical entity Component is identical to the substance Acequinocyl 57960-19-7 3-dodecyl-1,4-dioxo-1,4-dihydronaphthalen-2-yl acetate Acequinocyl C24H32O4 CC(=O)OC2=C(CCCCCCCCCCCC)C(=O)c1ccccc1C2=O InChI=1S/C24H32O4/c1-3-4-5-6-7-8-9-10-11-12-17-21-22(26)19-15-13-14-16-20(19)23(27)24(21)28-18(2)25/h13-16H,3-12,17H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The Netherlands Acequinocyl (Revised version of September 2007) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl. 02May2013 2013 doi:10.2903/j.efsa.2013.3212
+Acequinocyl 57960-19-7 single chemical entity Component is identical to the substance Acequinocyl 57960-19-7 3-dodecyl-1,4-dioxo-1,4-dihydronaphthalen-2-yl acetate Acequinocyl C24H32O4 CC(=O)OC2=C(CCCCCCCCCCCC)C(=O)c1ccccc1C2=O InChI=1S/C24H32O4/c1-3-4-5-6-7-8-9-10-11-12-17-21-22(26)19-15-13-14-16-20(19)23(27)24(21)28-18(2)25/h13-16H,3-12,17H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: The Netherlands Acequinocyl (Revised version of September 2007) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl. 02May2013 2013 doi:10.2903/j.efsa.2013.3212
+Acequinocyl 57960-19-7 single chemical entity Component is identical to the substance Acequinocyl 57960-19-7 3-dodecyl-1,4-dioxo-1,4-dihydronaphthalen-2-yl acetate Acequinocyl C24H32O4 CC(=O)OC2=C(CCCCCCCCCCCC)C(=O)c1ccccc1C2=O InChI=1S/C24H32O4/c1-3-4-5-6-7-8-9-10-11-12-17-21-22(26)19-15-13-14-16-20(19)23(27)24(21)28-18(2)25/h13-16H,3-12,17H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The Netherlands Acequinocyl (Revised version of September 2007) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl. 02May2013 2013 doi:10.2903/j.efsa.2013.3212
+Acequinocyl 57960-19-7 single chemical entity Component is identical to the substance Acequinocyl 57960-19-7 3-dodecyl-1,4-dioxo-1,4-dihydronaphthalen-2-yl acetate Acequinocyl C24H32O4 CC(=O)OC2=C(CCCCCCCCCCCC)C(=O)c1ccccc1C2=O InChI=1S/C24H32O4/c1-3-4-5-6-7-8-9-10-11-12-17-21-22(26)19-15-13-14-16-20(19)23(27)24(21)28-18(2)25/h13-16H,3-12,17H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The Netherlands Acequinocyl (Revised version of September 2007) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl. 02May2013 2013 doi:10.2903/j.efsa.2013.3212
+Acequinocyl 57960-19-7 single chemical entity Component is identical to the substance Acequinocyl 57960-19-7 3-dodecyl-1,4-dioxo-1,4-dihydronaphthalen-2-yl acetate Acequinocyl C24H32O4 CC(=O)OC2=C(CCCCCCCCCCCC)C(=O)c1ccccc1C2=O InChI=1S/C24H32O4/c1-3-4-5-6-7-8-9-10-11-12-17-21-22(26)19-15-13-14-16-20(19)23(27)24(21)28-18(2)25/h13-16H,3-12,17H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The Netherlands Acequinocyl (Revised version of September 2007) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl. 02May2013 2013 doi:10.2903/j.efsa.2013.3212
+Acequinocyl 57960-19-7 single chemical entity Component is identical to the substance Acequinocyl 57960-19-7 3-dodecyl-1,4-dioxo-1,4-dihydronaphthalen-2-yl acetate Acequinocyl C24H32O4 CC(=O)OC2=C(CCCCCCCCCCCC)C(=O)c1ccccc1C2=O InChI=1S/C24H32O4/c1-3-4-5-6-7-8-9-10-11-12-17-21-22(26)19-15-13-14-16-20(19)23(27)24(21)28-18(2)25/h13-16H,3-12,17H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: The Netherlands Acequinocyl (Revised version of September 2007) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl. 02May2013 2013 doi:10.2903/j.efsa.2013.3212
+Acequinocyl 57960-19-7 single chemical entity Component is identical to the substance Acequinocyl 57960-19-7 3-dodecyl-1,4-dioxo-1,4-dihydronaphthalen-2-yl acetate Acequinocyl C24H32O4 CC(=O)OC2=C(CCCCCCCCCCCC)C(=O)c1ccccc1C2=O InChI=1S/C24H32O4/c1-3-4-5-6-7-8-9-10-11-12-17-21-22(26)19-15-13-14-16-20(19)23(27)24(21)28-18(2)25/h13-16H,3-12,17H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The Netherlands Acequinocyl (Revised version of September 2007) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl. 02May2013 2013 doi:10.2903/j.efsa.2013.3212
+Acequinocyl 57960-19-7 single chemical entity Component is identical to the substance Acequinocyl 57960-19-7 3-dodecyl-1,4-dioxo-1,4-dihydronaphthalen-2-yl acetate Acequinocyl C24H32O4 CC(=O)OC2=C(CCCCCCCCCCCC)C(=O)c1ccccc1C2=O InChI=1S/C24H32O4/c1-3-4-5-6-7-8-9-10-11-12-17-21-22(26)19-15-13-14-16-20(19)23(27)24(21)28-18(2)25/h13-16H,3-12,17H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The Netherlands Acequinocyl (Revised version of September 2007) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl. 02May2013 2013 doi:10.2903/j.efsa.2013.3212
+Acequinocyl 57960-19-7 single chemical entity Component is a metabolite of the substance 2-(2-oxotetradecanoyl)benzoic acid 2-(2-oxododecanoyl)benzoic acid Not in list C19H26O4 O=C(O)c1ccccc1C(=O)C(=O)CCCCCCCCCC InChI=1/C19H26O4/c1-2-3-4-5-6-7-8-9-14-17(20)18(21)15-12-10-11-13-16(15)19(22)23/h10-13H,2-9,14H2,1H3,(H,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: The Netherlands Acequinocyl (Revised version of September 2007) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl. 02May2013 2013 doi:10.2903/j.efsa.2013.3212
+Acequinocyl 57960-19-7 single chemical entity Component is a metabolite of the substance 2-(2-oxotetradecanoyl)benzoic acid 2-(2-oxododecanoyl)benzoic acid Not in list C19H26O4 O=C(O)c1ccccc1C(=O)C(=O)CCCCCCCCCC InChI=1/C19H26O4/c1-2-3-4-5-6-7-8-9-14-17(20)18(21)15-12-10-11-13-16(15)19(22)23/h10-13H,2-9,14H2,1H3,(H,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The Netherlands Acequinocyl (Revised version of September 2007) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl. 02May2013 2013 doi:10.2903/j.efsa.2013.3212
+Acequinocyl 57960-19-7 single chemical entity Component is a metabolite of the substance 2-(2-oxotetradecanoyl)benzoic acid 2-(2-oxododecanoyl)benzoic acid Not in list C19H26O4 O=C(O)c1ccccc1C(=O)C(=O)CCCCCCCCCC InChI=1/C19H26O4/c1-2-3-4-5-6-7-8-9-14-17(20)18(21)15-12-10-11-13-16(15)19(22)23/h10-13H,2-9,14H2,1H3,(H,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The Netherlands Acequinocyl (Revised version of September 2007) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl. 02May2013 2013 doi:10.2903/j.efsa.2013.3212
+Acequinocyl 57960-19-7 single chemical entity Component is a metabolite of the substance 2-(2-oxotetradecanoyl)benzoic acid 2-(2-oxododecanoyl)benzoic acid Not in list C19H26O4 O=C(O)c1ccccc1C(=O)C(=O)CCCCCCCCCC InChI=1/C19H26O4/c1-2-3-4-5-6-7-8-9-14-17(20)18(21)15-12-10-11-13-16(15)19(22)23/h10-13H,2-9,14H2,1H3,(H,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The Netherlands Acequinocyl (Revised version of September 2007) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl. 02May2013 2013 doi:10.2903/j.efsa.2013.3212
+Acequinocyl 57960-19-7 single chemical entity Component is a metabolite of the substance 2-(2-oxotetradecanoyl)benzoic acid 2-(2-oxododecanoyl)benzoic acid Not in list C19H26O4 O=C(O)c1ccccc1C(=O)C(=O)CCCCCCCCCC InChI=1/C19H26O4/c1-2-3-4-5-6-7-8-9-14-17(20)18(21)15-12-10-11-13-16(15)19(22)23/h10-13H,2-9,14H2,1H3,(H,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The Netherlands Acequinocyl (Revised version of September 2007) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl. 02May2013 2013 doi:10.2903/j.efsa.2013.3212
+Acequinocyl 57960-19-7 single chemical entity Component is a metabolite of the substance 2-(2-oxotetradecanoyl)benzoic acid 2-(2-oxododecanoyl)benzoic acid Not in list C19H26O4 O=C(O)c1ccccc1C(=O)C(=O)CCCCCCCCCC InChI=1/C19H26O4/c1-2-3-4-5-6-7-8-9-14-17(20)18(21)15-12-10-11-13-16(15)19(22)23/h10-13H,2-9,14H2,1H3,(H,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The Netherlands Acequinocyl (Revised version of September 2007) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl. 02May2013 2013 doi:10.2903/j.efsa.2013.3212
+Acequinocyl 57960-19-7 single chemical entity Component is a metabolite of the substance 2-(2-oxotetradecanoyl)benzoic acid 2-(2-oxododecanoyl)benzoic acid Not in list C19H26O4 O=C(O)c1ccccc1C(=O)C(=O)CCCCCCCCCC InChI=1/C19H26O4/c1-2-3-4-5-6-7-8-9-14-17(20)18(21)15-12-10-11-13-16(15)19(22)23/h10-13H,2-9,14H2,1H3,(H,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The Netherlands Acequinocyl (Revised version of September 2007) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl. 02May2013 2013 doi:10.2903/j.efsa.2013.3212
+Acequinocyl 57960-19-7 single chemical entity Component is a metabolite of the substance 2-(2-oxotetradecanoyl)benzoic acid 2-(2-oxododecanoyl)benzoic acid Not in list C19H26O4 O=C(O)c1ccccc1C(=O)C(=O)CCCCCCCCCC InChI=1/C19H26O4/c1-2-3-4-5-6-7-8-9-14-17(20)18(21)15-12-10-11-13-16(15)19(22)23/h10-13H,2-9,14H2,1H3,(H,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The Netherlands Acequinocyl (Revised version of September 2007) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl. 02May2013 2013 doi:10.2903/j.efsa.2013.3212
+Acequinocyl 57960-19-7 single chemical entity Component is a metabolite of the substance 2-(2-oxotetradecanoyl)benzoic acid 2-(2-oxododecanoyl)benzoic acid Not in list C19H26O4 O=C(O)c1ccccc1C(=O)C(=O)CCCCCCCCCC InChI=1/C19H26O4/c1-2-3-4-5-6-7-8-9-14-17(20)18(21)15-12-10-11-13-16(15)19(22)23/h10-13H,2-9,14H2,1H3,(H,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: The Netherlands Acequinocyl (Revised version of September 2007) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl. 02May2013 2013 doi:10.2903/j.efsa.2013.3212
+Acequinocyl 57960-19-7 single chemical entity Component is a metabolite of the substance 2-(2-oxotetradecanoyl)benzoic acid 2-(2-oxododecanoyl)benzoic acid Not in list C19H26O4 O=C(O)c1ccccc1C(=O)C(=O)CCCCCCCCCC InChI=1/C19H26O4/c1-2-3-4-5-6-7-8-9-14-17(20)18(21)15-12-10-11-13-16(15)19(22)23/h10-13H,2-9,14H2,1H3,(H,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The Netherlands Acequinocyl (Revised version of September 2007) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl. 02May2013 2013 doi:10.2903/j.efsa.2013.3212
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is identical to the substance Acibenzolar-S-methyl 135158-54-2 Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester Acybenzolar-S-methyl C8H6N2OS2 CSC(=O)C1=C2C(=CC=C1)N=NS2 InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is identical to the substance Acibenzolar-S-methyl 135158-54-2 Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester Acybenzolar-S-methyl C8H6N2OS2 CSC(=O)C1=C2C(=CC=C1)N=NS2 InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is identical to the substance Acibenzolar-S-methyl 135158-54-2 Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester Acybenzolar-S-methyl C8H6N2OS2 CSC(=O)C1=C2C(=CC=C1)N=NS2 InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is identical to the substance Acibenzolar-S-methyl 135158-54-2 Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester Acybenzolar-S-methyl C8H6N2OS2 CSC(=O)C1=C2C(=CC=C1)N=NS2 InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is identical to the substance Acibenzolar-S-methyl 135158-54-2 Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester Acybenzolar-S-methyl C8H6N2OS2 CSC(=O)C1=C2C(=CC=C1)N=NS2 InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is identical to the substance Acibenzolar-S-methyl 135158-54-2 Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester Acybenzolar-S-methyl C8H6N2OS2 CSC(=O)C1=C2C(=CC=C1)N=NS2 InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is identical to the substance Acibenzolar-S-methyl 135158-54-2 Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester Acybenzolar-S-methyl C8H6N2OS2 CSC(=O)C1=C2C(=CC=C1)N=NS2 InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is identical to the substance Acibenzolar-S-methyl 135158-54-2 Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester Acybenzolar-S-methyl C8H6N2OS2 CSC(=O)C1=C2C(=CC=C1)N=NS2 InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is identical to the substance Acibenzolar-S-methyl 135158-54-2 Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester Acybenzolar-S-methyl C8H6N2OS2 CSC(=O)C1=C2C(=CC=C1)N=NS2 InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is identical to the substance Acibenzolar-S-methyl 135158-54-2 Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester Acybenzolar-S-methyl C8H6N2OS2 CSC(=O)C1=C2C(=CC=C1)N=NS2 InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+6-Benzyladenine 214-927-5 1214-39-7 single chemical entity Component is identical to the substance 6-Benzyladenine 214-927-5 1214-39-7 N-benzyl-7H-purin-6-amine 6-Benzyladenine C12H11N5 C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3 InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative small colonies RMS: The United Kingdom 6-Benzyladenine (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine 22Oct2010 2010 doi:10.2903/j.efsa.2010.1716
+6-Benzyladenine 214-927-5 1214-39-7 single chemical entity Component is identical to the substance 6-Benzyladenine 214-927-5 1214-39-7 N-benzyl-7H-purin-6-amine 6-Benzyladenine C12H11N5 C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3 InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative small colonies RMS: The United Kingdom 6-Benzyladenine (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine 22Oct2010 2010 doi:10.2903/j.efsa.2010.1716
+6-Benzyladenine 214-927-5 1214-39-7 single chemical entity Component is identical to the substance 6-Benzyladenine 214-927-5 1214-39-7 N-benzyl-7H-purin-6-amine 6-Benzyladenine C12H11N5 C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3 InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative large colonies RMS: The United Kingdom 6-Benzyladenine (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine 22Oct2010 2010 doi:10.2903/j.efsa.2010.1716
+6-Benzyladenine 214-927-5 1214-39-7 single chemical entity Component is identical to the substance 6-Benzyladenine 214-927-5 1214-39-7 N-benzyl-7H-purin-6-amine 6-Benzyladenine C12H11N5 C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3 InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative large colonies RMS: The United Kingdom 6-Benzyladenine (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine 22Oct2010 2010 doi:10.2903/j.efsa.2010.1716
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is identical to the substance Acibenzolar-S-methyl 135158-54-2 Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester Acybenzolar-S-methyl C8H6N2OS2 CSC(=O)C1=C2C(=CC=C1)N=NS2 InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Spain Acibenzolar-S-Methyl (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is identical to the substance Acibenzolar-S-methyl 135158-54-2 Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester Acybenzolar-S-methyl C8H6N2OS2 CSC(=O)C1=C2C(=CC=C1)N=NS2 InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Spain Acibenzolar-S-Methyl (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is identical to the substance Acibenzolar-S-methyl 135158-54-2 Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester Acybenzolar-S-methyl C8H6N2OS2 CSC(=O)C1=C2C(=CC=C1)N=NS2 InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Spain Acibenzolar-S-Methyl (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is identical to the substance Acibenzolar-S-methyl 135158-54-2 Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester Acybenzolar-S-methyl C8H6N2OS2 CSC(=O)C1=C2C(=CC=C1)N=NS2 InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Spain Acibenzolar-S-Methyl (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is identical to the substance Acibenzolar-S-methyl 135158-54-2 Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester Acybenzolar-S-methyl C8H6N2OS2 CSC(=O)C1=C2C(=CC=C1)N=NS2 InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Spain Acibenzolar-S-Methyl (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is identical to the substance Acibenzolar-S-methyl 135158-54-2 Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester Acybenzolar-S-methyl C8H6N2OS2 CSC(=O)C1=C2C(=CC=C1)N=NS2 InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Spain Acibenzolar-S-Methyl (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is identical to the substance Acibenzolar-S-methyl 135158-54-2 Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester Acybenzolar-S-methyl C8H6N2OS2 CSC(=O)C1=C2C(=CC=C1)N=NS2 InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Spain Acibenzolar-S-Methyl (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is identical to the substance Acibenzolar-S-methyl 135158-54-2 Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester Acybenzolar-S-methyl C8H6N2OS2 CSC(=O)C1=C2C(=CC=C1)N=NS2 InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Spain Acibenzolar-S-Methyl (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is identical to the substance Acibenzolar-S-methyl 135158-54-2 Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester Acybenzolar-S-methyl C8H6N2OS2 CSC(=O)C1=C2C(=CC=C1)N=NS2 InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Spain Acibenzolar-S-Methyl (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is identical to the substance Acibenzolar-S-methyl 135158-54-2 Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester Acybenzolar-S-methyl C8H6N2OS2 CSC(=O)C1=C2C(=CC=C1)N=NS2 InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Spain Acibenzolar-S-Methyl (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is identical to the substance Acibenzolar-S-methyl 135158-54-2 Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester Acybenzolar-S-methyl C8H6N2OS2 CSC(=O)C1=C2C(=CC=C1)N=NS2 InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Spain Acibenzolar-S-Methyl (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is identical to the substance Acibenzolar-S-methyl 135158-54-2 Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester Acybenzolar-S-methyl C8H6N2OS2 CSC(=O)C1=C2C(=CC=C1)N=NS2 InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Spain Acibenzolar-S-Methyl (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is identical to the substance Acibenzolar-S-methyl 135158-54-2 Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester Acybenzolar-S-methyl C8H6N2OS2 CSC(=O)C1=C2C(=CC=C1)N=NS2 InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative small colonies RMS: France - CoRMS: Spain Acibenzolar-S-Methyl (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is identical to the substance Acibenzolar-S-methyl 135158-54-2 Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester Acybenzolar-S-methyl C8H6N2OS2 CSC(=O)C1=C2C(=CC=C1)N=NS2 InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative large colonies RMS: France - CoRMS: Spain Acibenzolar-S-Methyl (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is identical to the substance Acibenzolar-S-methyl 135158-54-2 Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester Acybenzolar-S-methyl C8H6N2OS2 CSC(=O)C1=C2C(=CC=C1)N=NS2 InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative small colonies RMS: France - CoRMS: Spain Acibenzolar-S-Methyl (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is identical to the substance Acibenzolar-S-methyl 135158-54-2 Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester Acybenzolar-S-methyl C8H6N2OS2 CSC(=O)C1=C2C(=CC=C1)N=NS2 InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative large colonies RMS: France - CoRMS: Spain Acibenzolar-S-Methyl (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is identical to the substance Acibenzolar-S-methyl 135158-54-2 Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester Acybenzolar-S-methyl C8H6N2OS2 CSC(=O)C1=C2C(=CC=C1)N=NS2 InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 4 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: France - CoRMS: Spain Acibenzolar-S-Methyl (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is identical to the substance Acibenzolar-S-methyl 135158-54-2 Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester Acybenzolar-S-methyl C8H6N2OS2 CSC(=O)C1=C2C(=CC=C1)N=NS2 InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 4 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: France - CoRMS: Spain Acibenzolar-S-Methyl (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is a metabolite of the substance 1,2,3-benzothiadiazole-7-carboxylic acid 35272-27-6 1,2,3-benzothiadiazole-7-carboxylic acid Not in list C7H4N2O2S C1=CC(=C2C(=C1)N=NS2)C(=O)O InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Spain Acibenzolar-S-Methyl (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is a metabolite of the substance 1,2,3-benzothiadiazole-7-carboxylic acid 35272-27-6 1,2,3-benzothiadiazole-7-carboxylic acid Not in list C7H4N2O2S C1=CC(=C2C(=C1)N=NS2)C(=O)O InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Spain Acibenzolar-S-Methyl (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is a metabolite of the substance 1,2,3-benzothiadiazole-7-carboxylic acid 35272-27-6 1,2,3-benzothiadiazole-7-carboxylic acid Not in list C7H4N2O2S C1=CC(=C2C(=C1)N=NS2)C(=O)O InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Spain Acibenzolar-S-Methyl (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is a metabolite of the substance 1,2,3-benzothiadiazole-7-carboxylic acid 35272-27-6 1,2,3-benzothiadiazole-7-carboxylic acid Not in list C7H4N2O2S C1=CC(=C2C(=C1)N=NS2)C(=O)O InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Positive RMS: France - CoRMS: Spain Acibenzolar-S-Methyl (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is a metabolite of the substance 1,2,3-benzothiadiazole-7-carboxylic acid 35272-27-6 1,2,3-benzothiadiazole-7-carboxylic acid Not in list C7H4N2O2S C1=CC(=C2C(=C1)N=NS2)C(=O)O InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is a metabolite of the substance 1,2,3-benzothiadiazole-7-carboxylic acid 35272-27-6 1,2,3-benzothiadiazole-7-carboxylic acid Not in list C7H4N2O2S C1=CC(=C2C(=C1)N=NS2)C(=O)O InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is a metabolite of the substance 1,2,3-benzothiadiazole-7-carboxylic acid 35272-27-6 1,2,3-benzothiadiazole-7-carboxylic acid Not in list C7H4N2O2S C1=CC(=C2C(=C1)N=NS2)C(=O)O InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Positive RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is a metabolite of the substance 1,2,3-benzothiadiazole-7-carboxylic acid 35272-27-6 1,2,3-benzothiadiazole-7-carboxylic acid Not in list C7H4N2O2S C1=CC(=C2C(=C1)N=NS2)C(=O)O InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is a metabolite of the substance 1,2,3-benzothiadiazole-7-carboxylic acid 35272-27-6 1,2,3-benzothiadiazole-7-carboxylic acid Not in list C7H4N2O2S C1=CC(=C2C(=C1)N=NS2)C(=O)O InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is a metabolite of the substance 1,2,3-benzothiadiazole-7-carboxylic acid 35272-27-6 1,2,3-benzothiadiazole-7-carboxylic acid Not in list C7H4N2O2S C1=CC(=C2C(=C1)N=NS2)C(=O)O InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is a metabolite of the substance 1,2,3-benzothiadiazole-7-carboxylic acid 35272-27-6 1,2,3-benzothiadiazole-7-carboxylic acid Not in list C7H4N2O2S C1=CC(=C2C(=C1)N=NS2)C(=O)O InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is a metabolite of the substance 1,2,3-benzothiadiazole-7-carboxylic acid 35272-27-6 1,2,3-benzothiadiazole-7-carboxylic acid Not in list C7H4N2O2S C1=CC(=C2C(=C1)N=NS2)C(=O)O InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is a metabolite of the substance 1,2,3-benzothiadiazole-7-carboxylic acid 35272-27-6 1,2,3-benzothiadiazole-7-carboxylic acid Not in list C7H4N2O2S C1=CC(=C2C(=C1)N=NS2)C(=O)O InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is a metabolite of the substance 1,2,3-benzothiadiazole-7-carboxylic acid 35272-27-6 1,2,3-benzothiadiazole-7-carboxylic acid Not in list C7H4N2O2S C1=CC(=C2C(=C1)N=NS2)C(=O)O InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is a metabolite of the substance 1,2,3-benzothiadiazole-7-carboxylic acid 35272-27-6 1,2,3-benzothiadiazole-7-carboxylic acid Not in list C7H4N2O2S C1=CC(=C2C(=C1)N=NS2)C(=O)O InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is a metabolite of the substance 1,2,3-benzothiadiazole-7-carboxylic acid 35272-27-6 1,2,3-benzothiadiazole-7-carboxylic acid Not in list C7H4N2O2S C1=CC(=C2C(=C1)N=NS2)C(=O)O InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is a metabolite of the substance 1,2,3-benzothiadiazole-7-carboxylic acid 35272-27-6 1,2,3-benzothiadiazole-7-carboxylic acid Not in list C7H4N2O2S C1=CC(=C2C(=C1)N=NS2)C(=O)O InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is a metabolite of the substance 1,2,3-benzothiadiazole-7-carboxylic acid 35272-27-6 1,2,3-benzothiadiazole-7-carboxylic acid Not in list C7H4N2O2S C1=CC(=C2C(=C1)N=NS2)C(=O)O InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is a metabolite of the substance 1,2,3-benzothiadiazole-7-carboxylic acid 35272-27-6 1,2,3-benzothiadiazole-7-carboxylic acid Not in list C7H4N2O2S C1=CC(=C2C(=C1)N=NS2)C(=O)O InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is a metabolite of the substance 1,2,3-benzothiadiazole-7-carboxylic acid 35272-27-6 1,2,3-benzothiadiazole-7-carboxylic acid Not in list C7H4N2O2S C1=CC(=C2C(=C1)N=NS2)C(=O)O InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is a metabolite of the substance 1,2,3-benzothiadiazole-7-carboxylic acid 35272-27-6 1,2,3-benzothiadiazole-7-carboxylic acid Not in list C7H4N2O2S C1=CC(=C2C(=C1)N=NS2)C(=O)O InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is a metabolite of the substance 1,2,3-benzothiadiazole-7-carboxylic acid 35272-27-6 1,2,3-benzothiadiazole-7-carboxylic acid Not in list C7H4N2O2S C1=CC(=C2C(=C1)N=NS2)C(=O)O InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is a metabolite of the substance 1,2,3-benzothiadiazole-7-carboxylic acid 35272-27-6 1,2,3-benzothiadiazole-7-carboxylic acid Not in list C7H4N2O2S C1=CC(=C2C(=C1)N=NS2)C(=O)O InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is a metabolite of the substance 1,2,3-benzothiadiazole-7-carboxylic acid 35272-27-6 1,2,3-benzothiadiazole-7-carboxylic acid Not in list C7H4N2O2S C1=CC(=C2C(=C1)N=NS2)C(=O)O InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is a metabolite of the substance 4-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid 4-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid Not in list C7H4N2O3S O=C(O)c1ccc(O)c2nnsc12 InChI=1/C7H4N2O3S/c10-4-2-1-3(7(11)12)6-5(4)8-9-13-6/h1-2,10H,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is a metabolite of the substance 4-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid 4-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid Not in list C7H4N2O3S O=C(O)c1ccc(O)c2nnsc12 InChI=1/C7H4N2O3S/c10-4-2-1-3(7(11)12)6-5(4)8-9-13-6/h1-2,10H,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is a metabolite of the substance 4-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid 4-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid Not in list C7H4N2O3S O=C(O)c1ccc(O)c2nnsc12 InChI=1/C7H4N2O3S/c10-4-2-1-3(7(11)12)6-5(4)8-9-13-6/h1-2,10H,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is a metabolite of the substance 4-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid 4-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid Not in list C7H4N2O3S O=C(O)c1ccc(O)c2nnsc12 InChI=1/C7H4N2O3S/c10-4-2-1-3(7(11)12)6-5(4)8-9-13-6/h1-2,10H,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is a metabolite of the substance 4-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid 4-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid Not in list C7H4N2O3S O=C(O)c1ccc(O)c2nnsc12 InChI=1/C7H4N2O3S/c10-4-2-1-3(7(11)12)6-5(4)8-9-13-6/h1-2,10H,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is a metabolite of the substance 4-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid 4-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid Not in list C7H4N2O3S O=C(O)c1ccc(O)c2nnsc12 InChI=1/C7H4N2O3S/c10-4-2-1-3(7(11)12)6-5(4)8-9-13-6/h1-2,10H,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is a metabolite of the substance 4-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid 4-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid Not in list C7H4N2O3S O=C(O)c1ccc(O)c2nnsc12 InChI=1/C7H4N2O3S/c10-4-2-1-3(7(11)12)6-5(4)8-9-13-6/h1-2,10H,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is a metabolite of the substance 4-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid 4-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid Not in list C7H4N2O3S O=C(O)c1ccc(O)c2nnsc12 InChI=1/C7H4N2O3S/c10-4-2-1-3(7(11)12)6-5(4)8-9-13-6/h1-2,10H,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is a metabolite of the substance 4-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid 4-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid Not in list C7H4N2O3S O=C(O)c1ccc(O)c2nnsc12 InChI=1/C7H4N2O3S/c10-4-2-1-3(7(11)12)6-5(4)8-9-13-6/h1-2,10H,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is a metabolite of the substance 4-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid 4-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid Not in list C7H4N2O3S O=C(O)c1ccc(O)c2nnsc12 InChI=1/C7H4N2O3S/c10-4-2-1-3(7(11)12)6-5(4)8-9-13-6/h1-2,10H,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is a metabolite of the substance 4-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid 4-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid Not in list C7H4N2O3S O=C(O)c1ccc(O)c2nnsc12 InChI=1/C7H4N2O3S/c10-4-2-1-3(7(11)12)6-5(4)8-9-13-6/h1-2,10H,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is a metabolite of the substance 4-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid 4-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid Not in list C7H4N2O3S O=C(O)c1ccc(O)c2nnsc12 InChI=1/C7H4N2O3S/c10-4-2-1-3(7(11)12)6-5(4)8-9-13-6/h1-2,10H,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is a metabolite of the substance 5-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid 5-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid Not in list C7H4N2O3S O=C(O)c1cc(O)cc2nnsc12 InChI=1/C7H4N2O3S/c10-3-1-4(7(11)12)6-5(2-3)8-9-13-6/h1-2,10H,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is a metabolite of the substance 5-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid 5-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid Not in list C7H4N2O3S O=C(O)c1cc(O)cc2nnsc12 InChI=1/C7H4N2O3S/c10-3-1-4(7(11)12)6-5(2-3)8-9-13-6/h1-2,10H,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is a metabolite of the substance 5-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid 5-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid Not in list C7H4N2O3S O=C(O)c1cc(O)cc2nnsc12 InChI=1/C7H4N2O3S/c10-3-1-4(7(11)12)6-5(2-3)8-9-13-6/h1-2,10H,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is a metabolite of the substance 5-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid 5-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid Not in list C7H4N2O3S O=C(O)c1cc(O)cc2nnsc12 InChI=1/C7H4N2O3S/c10-3-1-4(7(11)12)6-5(2-3)8-9-13-6/h1-2,10H,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is a metabolite of the substance 5-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid 5-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid Not in list C7H4N2O3S O=C(O)c1cc(O)cc2nnsc12 InChI=1/C7H4N2O3S/c10-3-1-4(7(11)12)6-5(2-3)8-9-13-6/h1-2,10H,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is a metabolite of the substance 5-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid 5-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid Not in list C7H4N2O3S O=C(O)c1cc(O)cc2nnsc12 InChI=1/C7H4N2O3S/c10-3-1-4(7(11)12)6-5(2-3)8-9-13-6/h1-2,10H,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is a metabolite of the substance 5-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid 5-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid Not in list C7H4N2O3S O=C(O)c1cc(O)cc2nnsc12 InChI=1/C7H4N2O3S/c10-3-1-4(7(11)12)6-5(2-3)8-9-13-6/h1-2,10H,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is a metabolite of the substance 5-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid 5-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid Not in list C7H4N2O3S O=C(O)c1cc(O)cc2nnsc12 InChI=1/C7H4N2O3S/c10-3-1-4(7(11)12)6-5(2-3)8-9-13-6/h1-2,10H,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is a metabolite of the substance 5-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid 5-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid Not in list C7H4N2O3S O=C(O)c1cc(O)cc2nnsc12 InChI=1/C7H4N2O3S/c10-3-1-4(7(11)12)6-5(2-3)8-9-13-6/h1-2,10H,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is a metabolite of the substance 5-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid 5-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid Not in list C7H4N2O3S O=C(O)c1cc(O)cc2nnsc12 InChI=1/C7H4N2O3S/c10-3-1-4(7(11)12)6-5(2-3)8-9-13-6/h1-2,10H,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is a metabolite of the substance 5-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid 5-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid Not in list C7H4N2O3S O=C(O)c1cc(O)cc2nnsc12 InChI=1/C7H4N2O3S/c10-3-1-4(7(11)12)6-5(2-3)8-9-13-6/h1-2,10H,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Acibenzolar-S-methyl 135158-54-2 single chemical entity Component is a metabolite of the substance 5-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid 5-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid Not in list C7H4N2O3S O=C(O)c1cc(O)cc2nnsc12 InChI=1/C7H4N2O3S/c10-3-1-4(7(11)12)6-5(2-3)8-9-13-6/h1-2,10H,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: France Acibenzolar-s-methyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl 12Aug2014 2014 doi:10.2903/j.efsa.2014.3691
+Aclonifen 277-704-1 74070-46-5 single chemical entity Component is identical to the substance Aclonifen 277-704-1 74070-46-5 2-chloro-6-nitro-3-phenoxyaniline Aclonifen C12H9ClN2O3 Clc2c(N)c(ccc2Oc1ccccc1)[N+]([O-])=O InChI=1S/C12H9ClN2O3/c13-11-10(18-8-4-2-1-3-5-8)7-6-9(12(11)14)15(16)17/h1-7H,14H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Germany Aclonifen 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Aclonifen 21Oct2008 2008 doi:10.2903/j.efsa.2008.149r
+Aclonifen 277-704-1 74070-46-5 single chemical entity Component is identical to the substance Aclonifen 277-704-1 74070-46-5 2-chloro-6-nitro-3-phenoxyaniline Aclonifen C12H9ClN2O3 Clc2c(N)c(ccc2Oc1ccccc1)[N+]([O-])=O InChI=1S/C12H9ClN2O3/c13-11-10(18-8-4-2-1-3-5-8)7-6-9(12(11)14)15(16)17/h1-7H,14H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Germany Aclonifen 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Aclonifen 21Oct2008 2008 doi:10.2903/j.efsa.2008.149r
+Aclonifen 277-704-1 74070-46-5 single chemical entity Component is identical to the substance Aclonifen 277-704-1 74070-46-5 2-chloro-6-nitro-3-phenoxyaniline Aclonifen C12H9ClN2O3 Clc2c(N)c(ccc2Oc1ccccc1)[N+]([O-])=O InChI=1S/C12H9ClN2O3/c13-11-10(18-8-4-2-1-3-5-8)7-6-9(12(11)14)15(16)17/h1-7H,14H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Germany Aclonifen 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Aclonifen 21Oct2008 2008 doi:10.2903/j.efsa.2008.149r
+Aclonifen 277-704-1 74070-46-5 single chemical entity Component is identical to the substance Aclonifen 277-704-1 74070-46-5 2-chloro-6-nitro-3-phenoxyaniline Aclonifen C12H9ClN2O3 Clc2c(N)c(ccc2Oc1ccccc1)[N+]([O-])=O InChI=1S/C12H9ClN2O3/c13-11-10(18-8-4-2-1-3-5-8)7-6-9(12(11)14)15(16)17/h1-7H,14H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: Germany Aclonifen 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Aclonifen 21Oct2008 2008 doi:10.2903/j.efsa.2008.149r
+Aclonifen 277-704-1 74070-46-5 single chemical entity Component is identical to the substance Aclonifen 277-704-1 74070-46-5 2-chloro-6-nitro-3-phenoxyaniline Aclonifen C12H9ClN2O3 Clc2c(N)c(ccc2Oc1ccccc1)[N+]([O-])=O InChI=1S/C12H9ClN2O3/c13-11-10(18-8-4-2-1-3-5-8)7-6-9(12(11)14)15(16)17/h1-7H,14H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Germany Aclonifen 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Aclonifen 21Oct2008 2008 doi:10.2903/j.efsa.2008.149r
+Aclonifen 277-704-1 74070-46-5 single chemical entity Component is identical to the substance Aclonifen 277-704-1 74070-46-5 2-chloro-6-nitro-3-phenoxyaniline Aclonifen C12H9ClN2O3 Clc2c(N)c(ccc2Oc1ccccc1)[N+]([O-])=O InChI=1S/C12H9ClN2O3/c13-11-10(18-8-4-2-1-3-5-8)7-6-9(12(11)14)15(16)17/h1-7H,14H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: Germany Aclonifen 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Aclonifen 21Oct2008 2008 doi:10.2903/j.efsa.2008.149r
+Aclonifen 277-704-1 74070-46-5 single chemical entity Component is identical to the substance Aclonifen 277-704-1 74070-46-5 2-chloro-6-nitro-3-phenoxyaniline Aclonifen C12H9ClN2O3 Clc2c(N)c(ccc2Oc1ccccc1)[N+]([O-])=O InChI=1S/C12H9ClN2O3/c13-11-10(18-8-4-2-1-3-5-8)7-6-9(12(11)14)15(16)17/h1-7H,14H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Germany Aclonifen 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Aclonifen 21Oct2008 2008 doi:10.2903/j.efsa.2008.149r
+Aclonifen 277-704-1 74070-46-5 single chemical entity Component is identical to the substance Aclonifen 277-704-1 74070-46-5 2-chloro-6-nitro-3-phenoxyaniline Aclonifen C12H9ClN2O3 Clc2c(N)c(ccc2Oc1ccccc1)[N+]([O-])=O InChI=1S/C12H9ClN2O3/c13-11-10(18-8-4-2-1-3-5-8)7-6-9(12(11)14)15(16)17/h1-7H,14H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Germany Aclonifen 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Aclonifen 21Oct2008 2008 doi:10.2903/j.efsa.2008.149r
+Aclonifen 277-704-1 74070-46-5 single chemical entity Component is identical to the substance Aclonifen 277-704-1 74070-46-5 2-chloro-6-nitro-3-phenoxyaniline Aclonifen C12H9ClN2O3 Clc2c(N)c(ccc2Oc1ccccc1)[N+]([O-])=O InChI=1S/C12H9ClN2O3/c13-11-10(18-8-4-2-1-3-5-8)7-6-9(12(11)14)15(16)17/h1-7H,14H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Germany Aclonifen 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Aclonifen 21Oct2008 2008 doi:10.2903/j.efsa.2008.149r
+Aclonifen 277-704-1 74070-46-5 single chemical entity Component is identical to the substance Aclonifen 277-704-1 74070-46-5 2-chloro-6-nitro-3-phenoxyaniline Aclonifen C12H9ClN2O3 Clc2c(N)c(ccc2Oc1ccccc1)[N+]([O-])=O InChI=1S/C12H9ClN2O3/c13-11-10(18-8-4-2-1-3-5-8)7-6-9(12(11)14)15(16)17/h1-7H,14H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Germany Aclonifen 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Aclonifen 21Oct2008 2008 doi:10.2903/j.efsa.2008.149r
+Aclonifen 277-704-1 74070-46-5 single chemical entity Component is identical to the substance Aclonifen 277-704-1 74070-46-5 2-chloro-6-nitro-3-phenoxyaniline Aclonifen C12H9ClN2O3 Clc2c(N)c(ccc2Oc1ccccc1)[N+]([O-])=O InChI=1S/C12H9ClN2O3/c13-11-10(18-8-4-2-1-3-5-8)7-6-9(12(11)14)15(16)17/h1-7H,14H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Germany Aclonifen 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Aclonifen 21Oct2008 2008 doi:10.2903/j.efsa.2008.149r
+Aclonifen 277-704-1 74070-46-5 single chemical entity Component is identical to the substance Aclonifen 277-704-1 74070-46-5 2-chloro-6-nitro-3-phenoxyaniline Aclonifen C12H9ClN2O3 Clc2c(N)c(ccc2Oc1ccccc1)[N+]([O-])=O InChI=1S/C12H9ClN2O3/c13-11-10(18-8-4-2-1-3-5-8)7-6-9(12(11)14)15(16)17/h1-7H,14H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes without Negative RMS: Germany Aclonifen 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Aclonifen 21Oct2008 2008 doi:10.2903/j.efsa.2008.149r
+Aclonifen 277-704-1 74070-46-5 single chemical entity Component is identical to the substance Aclonifen 277-704-1 74070-46-5 2-chloro-6-nitro-3-phenoxyaniline Aclonifen C12H9ClN2O3 Clc2c(N)c(ccc2Oc1ccccc1)[N+]([O-])=O InChI=1S/C12H9ClN2O3/c13-11-10(18-8-4-2-1-3-5-8)7-6-9(12(11)14)15(16)17/h1-7H,14H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Germany Aclonifen 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Aclonifen 21Oct2008 2008 doi:10.2903/j.efsa.2008.149r
+Aclonifen 277-704-1 74070-46-5 single chemical entity Component is identical to the substance Aclonifen 277-704-1 74070-46-5 2-chloro-6-nitro-3-phenoxyaniline Aclonifen C12H9ClN2O3 Clc2c(N)c(ccc2Oc1ccccc1)[N+]([O-])=O InChI=1S/C12H9ClN2O3/c13-11-10(18-8-4-2-1-3-5-8)7-6-9(12(11)14)15(16)17/h1-7H,14H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Germany Aclonifen 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Aclonifen 21Oct2008 2008 doi:10.2903/j.efsa.2008.149r
+Aclonifen 277-704-1 74070-46-5 single chemical entity Component is identical to the substance Aclonifen 277-704-1 74070-46-5 2-chloro-6-nitro-3-phenoxyaniline Aclonifen C12H9ClN2O3 Clc2c(N)c(ccc2Oc1ccccc1)[N+]([O-])=O InChI=1S/C12H9ClN2O3/c13-11-10(18-8-4-2-1-3-5-8)7-6-9(12(11)14)15(16)17/h1-7H,14H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes with Negative RMS: Germany Aclonifen 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Aclonifen 21Oct2008 2008 doi:10.2903/j.efsa.2008.149r
+Aclonifen 277-704-1 74070-46-5 single chemical entity Component is identical to the substance Aclonifen 277-704-1 74070-46-5 2-chloro-6-nitro-3-phenoxyaniline Aclonifen C12H9ClN2O3 Clc2c(N)c(ccc2Oc1ccccc1)[N+]([O-])=O InChI=1S/C12H9ClN2O3/c13-11-10(18-8-4-2-1-3-5-8)7-6-9(12(11)14)15(16)17/h1-7H,14H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Germany Aclonifen 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Aclonifen 21Oct2008 2008 doi:10.2903/j.efsa.2008.149r
+Aclonifen 277-704-1 74070-46-5 single chemical entity Component is identical to the substance Aclonifen 277-704-1 74070-46-5 2-chloro-6-nitro-3-phenoxyaniline Aclonifen C12H9ClN2O3 Clc2c(N)c(ccc2Oc1ccccc1)[N+]([O-])=O InChI=1S/C12H9ClN2O3/c13-11-10(18-8-4-2-1-3-5-8)7-6-9(12(11)14)15(16)17/h1-7H,14H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Germany Aclonifen 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Aclonifen 21Oct2008 2008 doi:10.2903/j.efsa.2008.149r
+Aclonifen 277-704-1 74070-46-5 single chemical entity Component is identical to the substance Aclonifen 277-704-1 74070-46-5 2-chloro-6-nitro-3-phenoxyaniline Aclonifen C12H9ClN2O3 Clc2c(N)c(ccc2Oc1ccccc1)[N+]([O-])=O InChI=1S/C12H9ClN2O3/c13-11-10(18-8-4-2-1-3-5-8)7-6-9(12(11)14)15(16)17/h1-7H,14H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Germany Aclonifen 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Aclonifen 21Oct2008 2008 doi:10.2903/j.efsa.2008.149r
+Aclonifen 277-704-1 74070-46-5 single chemical entity Component is identical to the substance Aclonifen 277-704-1 74070-46-5 2-chloro-6-nitro-3-phenoxyaniline Aclonifen C12H9ClN2O3 Clc2c(N)c(ccc2Oc1ccccc1)[N+]([O-])=O InChI=1S/C12H9ClN2O3/c13-11-10(18-8-4-2-1-3-5-8)7-6-9(12(11)14)15(16)17/h1-7H,14H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Germany Aclonifen 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Aclonifen 21Oct2008 2008 doi:10.2903/j.efsa.2008.149r
+Aclonifen 277-704-1 74070-46-5 single chemical entity Component is identical to the substance Aclonifen 277-704-1 74070-46-5 2-chloro-6-nitro-3-phenoxyaniline Aclonifen C12H9ClN2O3 Clc2c(N)c(ccc2Oc1ccccc1)[N+]([O-])=O InChI=1S/C12H9ClN2O3/c13-11-10(18-8-4-2-1-3-5-8)7-6-9(12(11)14)15(16)17/h1-7H,14H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Germany Aclonifen 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Aclonifen 21Oct2008 2008 doi:10.2903/j.efsa.2008.149r
+2,4-D 202-361-1 94-75-7 single chemical entity Component is identical to the substance 2,4-D 202-361-1 94-75-7 (2,4-dichlorophenoxy)acetic acid 2,4-D C8H6Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCC(=O)O InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-D 202-361-1 94-75-7 single chemical entity Component is identical to the substance 2,4-D 202-361-1 94-75-7 (2,4-dichlorophenoxy)acetic acid 2,4-D C8H6Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCC(=O)O InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-D 202-361-1 94-75-7 single chemical entity Component is identical to the substance 2,4-D 202-361-1 94-75-7 (2,4-dichlorophenoxy)acetic acid 2,4-D C8H6Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCC(=O)O InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-D 202-361-1 94-75-7 single chemical entity Component is identical to the substance 2,4-D 202-361-1 94-75-7 (2,4-dichlorophenoxy)acetic acid 2,4-D C8H6Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCC(=O)O InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-D 202-361-1 94-75-7 single chemical entity Component is identical to the substance 2,4-D 202-361-1 94-75-7 (2,4-dichlorophenoxy)acetic acid 2,4-D C8H6Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCC(=O)O InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-D 202-361-1 94-75-7 single chemical entity Component is identical to the substance 2,4-D 202-361-1 94-75-7 (2,4-dichlorophenoxy)acetic acid 2,4-D C8H6Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCC(=O)O InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-D 202-361-1 94-75-7 single chemical entity Component is identical to the substance 2,4-D 202-361-1 94-75-7 (2,4-dichlorophenoxy)acetic acid 2,4-D C8H6Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCC(=O)O InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-D 202-361-1 94-75-7 single chemical entity Component is identical to the substance 2,4-D 202-361-1 94-75-7 (2,4-dichlorophenoxy)acetic acid 2,4-D C8H6Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCC(=O)O InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-D 202-361-1 94-75-7 single chemical entity Component is identical to the substance 2,4-D 202-361-1 94-75-7 (2,4-dichlorophenoxy)acetic acid 2,4-D C8H6Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCC(=O)O InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-D 202-361-1 94-75-7 single chemical entity Component is identical to the substance 2,4-D 202-361-1 94-75-7 (2,4-dichlorophenoxy)acetic acid 2,4-D C8H6Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCC(=O)O InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-D 202-361-1 94-75-7 single chemical entity Component is identical to the substance 2,4-D 202-361-1 94-75-7 (2,4-dichlorophenoxy)acetic acid 2,4-D C8H6Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCC(=O)O InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-D 202-361-1 94-75-7 single chemical entity Component is identical to the substance 2,4-D 202-361-1 94-75-7 (2,4-dichlorophenoxy)acetic acid 2,4-D C8H6Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCC(=O)O InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-D 202-361-1 94-75-7 single chemical entity Component is identical to the substance 2,4-D 202-361-1 94-75-7 (2,4-dichlorophenoxy)acetic acid 2,4-D C8H6Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCC(=O)O InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo Equivalent or similar to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) Yes Acceptable Rat (as animal) Not reported 5 Male/Female oral: gavage 4.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-D 202-361-1 94-75-7 single chemical entity Component is identical to the substance 2,4-D 202-361-1 94-75-7 (2,4-dichlorophenoxy)acetic acid 2,4-D C8H6Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCC(=O)O InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo Equivalent or similar to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) Yes Acceptable Rat (as animal) Not reported 5 Male/Female oral: gavage 14.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-D 202-361-1 94-75-7 single chemical entity Component is identical to the substance 2,4-D 202-361-1 94-75-7 (2,4-dichlorophenoxy)acetic acid 2,4-D C8H6Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCC(=O)O InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-D 202-361-1 94-75-7 single chemical entity Component is identical to the substance 2,4-D 202-361-1 94-75-7 (2,4-dichlorophenoxy)acetic acid 2,4-D C8H6Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCC(=O)O InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is identical to the substance 2,4-DB 202-366-9 94-82-6 4-(2,4-dichlorophenoxy)butanoic acid 2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB) C10H10Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Ambiguous RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is identical to the substance 2,4-DB 202-366-9 94-82-6 4-(2,4-dichlorophenoxy)butanoic acid 2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB) C10H10Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+Acrinathrin 101007-06-1 single chemical entity Component is identical to the substance Acrinathrin 101007-06-1 [(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate Acrinathrin C26H21F6NO5 CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Acrinathrin (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin. 19Dec2013 2013 doi:10.2903/j.efsa.2013.3469
+Acrinathrin 101007-06-1 single chemical entity Component is identical to the substance Acrinathrin 101007-06-1 [(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate Acrinathrin C26H21F6NO5 CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Acrinathrin (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin. 19Dec2013 2013 doi:10.2903/j.efsa.2013.3469
+Acrinathrin 101007-06-1 single chemical entity Component is identical to the substance Acrinathrin 101007-06-1 [(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate Acrinathrin C26H21F6NO5 CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Acrinathrin (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin. 19Dec2013 2013 doi:10.2903/j.efsa.2013.3469
+Acrinathrin 101007-06-1 single chemical entity Component is identical to the substance Acrinathrin 101007-06-1 [(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate Acrinathrin C26H21F6NO5 CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Acrinathrin (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin. 19Dec2013 2013 doi:10.2903/j.efsa.2013.3469
+Acrinathrin 101007-06-1 single chemical entity Component is identical to the substance Acrinathrin 101007-06-1 [(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate Acrinathrin C26H21F6NO5 CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Acrinathrin (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin. 19Dec2013 2013 doi:10.2903/j.efsa.2013.3469
+Acrinathrin 101007-06-1 single chemical entity Component is identical to the substance Acrinathrin 101007-06-1 [(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate Acrinathrin C26H21F6NO5 CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Acrinathrin (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin. 19Dec2013 2013 doi:10.2903/j.efsa.2013.3469
+Acrinathrin 101007-06-1 single chemical entity Component is identical to the substance Acrinathrin 101007-06-1 [(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate Acrinathrin C26H21F6NO5 CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: France Acrinathrin (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin. 19Dec2013 2013 doi:10.2903/j.efsa.2013.3469
+Acrinathrin 101007-06-1 single chemical entity Component is identical to the substance Acrinathrin 101007-06-1 [(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate Acrinathrin C26H21F6NO5 CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Acrinathrin (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin. 19Dec2013 2013 doi:10.2903/j.efsa.2013.3469
+Acrinathrin 101007-06-1 single chemical entity Component is identical to the substance Acrinathrin 101007-06-1 [(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate Acrinathrin C26H21F6NO5 CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Acrinathrin (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin. 19Dec2013 2013 doi:10.2903/j.efsa.2013.3469
+Acrinathrin 101007-06-1 single chemical entity Component is identical to the substance Acrinathrin 101007-06-1 [(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate Acrinathrin C26H21F6NO5 CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: France Acrinathrin (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin. 19Dec2013 2013 doi:10.2903/j.efsa.2013.3469
+Acrinathrin 101007-06-1 single chemical entity Component is identical to the substance Acrinathrin 101007-06-1 [(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate Acrinathrin C26H21F6NO5 CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: France Acrinathrin (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin. 19Dec2013 2013 doi:10.2903/j.efsa.2013.3469
+Acrinathrin 101007-06-1 single chemical entity Component is identical to the substance Acrinathrin 101007-06-1 [(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate Acrinathrin C26H21F6NO5 CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: France Acrinathrin (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin. 19Dec2013 2013 doi:10.2903/j.efsa.2013.3469
+Acrinathrin 101007-06-1 single chemical entity Component is identical to the substance Acrinathrin 101007-06-1 [(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate Acrinathrin C26H21F6NO5 CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: France Acrinathrin (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin. 19Dec2013 2013 doi:10.2903/j.efsa.2013.3469
+Acrinathrin 101007-06-1 single chemical entity Component is identical to the substance Acrinathrin 101007-06-1 [(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate Acrinathrin C26H21F6NO5 CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: France Acrinathrin (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin. 19Dec2013 2013 doi:10.2903/j.efsa.2013.3469
+Acrinathrin 101007-06-1 single chemical entity Component is a metabolite of the substance (2Z)-3-(3-{[cyano(3-phenoxyphenyl)methoxy]carbonyl}-2,2-dimethylcyclopropyl)prop-2-enoic acid (2Z)-3-(3-{[cyano(3-phenoxyphenyl)methoxy]carbonyl}-2,2-dimethylcyclopropyl)prop-2-enoic acid Acrinathrin C23H21NO5 OC(=O)/C=C\C3C(C(=O)OC(C#N)c2cccc(Oc1ccccc1)c2)C3(C)C InChI=1/C23H21NO5/c1-23(2)18(11-12-20(25)26)21(23)22(27)29-19(14-24)15-7-6-10-17(13-15)28-16-8-4-3-5-9-16/h3-13,18-19,21H,1-2H3,(H,25,26)/b12-11- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: France Acrinathrin (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin. 19Dec2013 2013 doi:10.2903/j.efsa.2013.3469
+Acrinathrin 101007-06-1 single chemical entity Component is a metabolite of the substance (2Z)-3-(3-{[cyano(3-phenoxyphenyl)methoxy]carbonyl}-2,2-dimethylcyclopropyl)prop-2-enoic acid (2Z)-3-(3-{[cyano(3-phenoxyphenyl)methoxy]carbonyl}-2,2-dimethylcyclopropyl)prop-2-enoic acid Acrinathrin C23H21NO5 OC(=O)/C=C\C3C(C(=O)OC(C#N)c2cccc(Oc1ccccc1)c2)C3(C)C InChI=1/C23H21NO5/c1-23(2)18(11-12-20(25)26)21(23)22(27)29-19(14-24)15-7-6-10-17(13-15)28-16-8-4-3-5-9-16/h3-13,18-19,21H,1-2H3,(H,25,26)/b12-11- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: France Acrinathrin (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin. 19Dec2013 2013 doi:10.2903/j.efsa.2013.3469
+Acrinathrin 101007-06-1 single chemical entity Component is a metabolite of the substance (2Z)-3-(3-{[cyano(3-phenoxyphenyl)methoxy]carbonyl}-2,2-dimethylcyclopropyl)prop-2-enoic acid (2Z)-3-(3-{[cyano(3-phenoxyphenyl)methoxy]carbonyl}-2,2-dimethylcyclopropyl)prop-2-enoic acid Acrinathrin C23H21NO5 OC(=O)/C=C\C3C(C(=O)OC(C#N)c2cccc(Oc1ccccc1)c2)C3(C)C InChI=1/C23H21NO5/c1-23(2)18(11-12-20(25)26)21(23)22(27)29-19(14-24)15-7-6-10-17(13-15)28-16-8-4-3-5-9-16/h3-13,18-19,21H,1-2H3,(H,25,26)/b12-11- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: France Acrinathrin (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin. 19Dec2013 2013 doi:10.2903/j.efsa.2013.3469
+Acrinathrin 101007-06-1 single chemical entity Component is a metabolite of the substance (2Z)-3-(3-{[cyano(3-phenoxyphenyl)methoxy]carbonyl}-2,2-dimethylcyclopropyl)prop-2-enoic acid (2Z)-3-(3-{[cyano(3-phenoxyphenyl)methoxy]carbonyl}-2,2-dimethylcyclopropyl)prop-2-enoic acid Acrinathrin C23H21NO5 OC(=O)/C=C\C3C(C(=O)OC(C#N)c2cccc(Oc1ccccc1)c2)C3(C)C InChI=1/C23H21NO5/c1-23(2)18(11-12-20(25)26)21(23)22(27)29-19(14-24)15-7-6-10-17(13-15)28-16-8-4-3-5-9-16/h3-13,18-19,21H,1-2H3,(H,25,26)/b12-11- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: France Acrinathrin (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin. 19Dec2013 2013 doi:10.2903/j.efsa.2013.3469
+Acrinathrin 101007-06-1 single chemical entity Component is a metabolite of the substance (2Z)-3-(3-{[cyano(3-phenoxyphenyl)methoxy]carbonyl}-2,2-dimethylcyclopropyl)prop-2-enoic acid (2Z)-3-(3-{[cyano(3-phenoxyphenyl)methoxy]carbonyl}-2,2-dimethylcyclopropyl)prop-2-enoic acid Acrinathrin C23H21NO5 OC(=O)/C=C\C3C(C(=O)OC(C#N)c2cccc(Oc1ccccc1)c2)C3(C)C InChI=1/C23H21NO5/c1-23(2)18(11-12-20(25)26)21(23)22(27)29-19(14-24)15-7-6-10-17(13-15)28-16-8-4-3-5-9-16/h3-13,18-19,21H,1-2H3,(H,25,26)/b12-11- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes without Negative RMS: France Acrinathrin (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin. 19Dec2013 2013 doi:10.2903/j.efsa.2013.3469
+Acrinathrin 101007-06-1 single chemical entity Component is a metabolite of the substance (2Z)-3-(3-{[cyano(3-phenoxyphenyl)methoxy]carbonyl}-2,2-dimethylcyclopropyl)prop-2-enoic acid (2Z)-3-(3-{[cyano(3-phenoxyphenyl)methoxy]carbonyl}-2,2-dimethylcyclopropyl)prop-2-enoic acid Acrinathrin C23H21NO5 OC(=O)/C=C\C3C(C(=O)OC(C#N)c2cccc(Oc1ccccc1)c2)C3(C)C InChI=1/C23H21NO5/c1-23(2)18(11-12-20(25)26)21(23)22(27)29-19(14-24)15-7-6-10-17(13-15)28-16-8-4-3-5-9-16/h3-13,18-19,21H,1-2H3,(H,25,26)/b12-11- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: France Acrinathrin (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin. 19Dec2013 2013 doi:10.2903/j.efsa.2013.3469
+Acrinathrin 101007-06-1 single chemical entity Component is a metabolite of the substance (2Z)-3-(3-{[cyano(3-phenoxyphenyl)methoxy]carbonyl}-2,2-dimethylcyclopropyl)prop-2-enoic acid (2Z)-3-(3-{[cyano(3-phenoxyphenyl)methoxy]carbonyl}-2,2-dimethylcyclopropyl)prop-2-enoic acid Acrinathrin C23H21NO5 OC(=O)/C=C\C3C(C(=O)OC(C#N)c2cccc(Oc1ccccc1)c2)C3(C)C InChI=1/C23H21NO5/c1-23(2)18(11-12-20(25)26)21(23)22(27)29-19(14-24)15-7-6-10-17(13-15)28-16-8-4-3-5-9-16/h3-13,18-19,21H,1-2H3,(H,25,26)/b12-11- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: France Acrinathrin (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin. 19Dec2013 2013 doi:10.2903/j.efsa.2013.3469
+Acrinathrin 101007-06-1 single chemical entity Component is a metabolite of the substance (2Z)-3-(3-{[cyano(3-phenoxyphenyl)methoxy]carbonyl}-2,2-dimethylcyclopropyl)prop-2-enoic acid (2Z)-3-(3-{[cyano(3-phenoxyphenyl)methoxy]carbonyl}-2,2-dimethylcyclopropyl)prop-2-enoic acid Acrinathrin C23H21NO5 OC(=O)/C=C\C3C(C(=O)OC(C#N)c2cccc(Oc1ccccc1)c2)C3(C)C InChI=1/C23H21NO5/c1-23(2)18(11-12-20(25)26)21(23)22(27)29-19(14-24)15-7-6-10-17(13-15)28-16-8-4-3-5-9-16/h3-13,18-19,21H,1-2H3,(H,25,26)/b12-11- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: France Acrinathrin (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin. 19Dec2013 2013 doi:10.2903/j.efsa.2013.3469
+Acrinathrin 101007-06-1 single chemical entity Component is a metabolite of the substance (2Z)-3-(3-{[cyano(3-phenoxyphenyl)methoxy]carbonyl}-2,2-dimethylcyclopropyl)prop-2-enoic acid (2Z)-3-(3-{[cyano(3-phenoxyphenyl)methoxy]carbonyl}-2,2-dimethylcyclopropyl)prop-2-enoic acid Acrinathrin C23H21NO5 OC(=O)/C=C\C3C(C(=O)OC(C#N)c2cccc(Oc1ccccc1)c2)C3(C)C InChI=1/C23H21NO5/c1-23(2)18(11-12-20(25)26)21(23)22(27)29-19(14-24)15-7-6-10-17(13-15)28-16-8-4-3-5-9-16/h3-13,18-19,21H,1-2H3,(H,25,26)/b12-11- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes with Negative RMS: France Acrinathrin (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin. 19Dec2013 2013 doi:10.2903/j.efsa.2013.3469
+Acrinathrin 101007-06-1 single chemical entity Component is a metabolite of the substance (2Z)-3-(3-{[cyano(3-phenoxyphenyl)methoxy]carbonyl}-2,2-dimethylcyclopropyl)prop-2-enoic acid (2Z)-3-(3-{[cyano(3-phenoxyphenyl)methoxy]carbonyl}-2,2-dimethylcyclopropyl)prop-2-enoic acid Acrinathrin C23H21NO5 OC(=O)/C=C\C3C(C(=O)OC(C#N)c2cccc(Oc1ccccc1)c2)C3(C)C InChI=1/C23H21NO5/c1-23(2)18(11-12-20(25)26)21(23)22(27)29-19(14-24)15-7-6-10-17(13-15)28-16-8-4-3-5-9-16/h3-13,18-19,21H,1-2H3,(H,25,26)/b12-11- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: France Acrinathrin (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin. 19Dec2013 2013 doi:10.2903/j.efsa.2013.3469
+Acrinathrin 101007-06-1 single chemical entity Component is a metabolite of the substance (2Z)-3-(3-{[cyano(3-phenoxyphenyl)methoxy]carbonyl}-2,2-dimethylcyclopropyl)prop-2-enoic acid (2Z)-3-(3-{[cyano(3-phenoxyphenyl)methoxy]carbonyl}-2,2-dimethylcyclopropyl)prop-2-enoic acid Acrinathrin C23H21NO5 OC(=O)/C=C\C3C(C(=O)OC(C#N)c2cccc(Oc1ccccc1)c2)C3(C)C InChI=1/C23H21NO5/c1-23(2)18(11-12-20(25)26)21(23)22(27)29-19(14-24)15-7-6-10-17(13-15)28-16-8-4-3-5-9-16/h3-13,18-19,21H,1-2H3,(H,25,26)/b12-11- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: France Acrinathrin (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin. 19Dec2013 2013 doi:10.2903/j.efsa.2013.3469
+Acrinathrin 101007-06-1 single chemical entity Component is a metabolite of the substance (2Z)-3-(3-{[cyano(3-phenoxyphenyl)methoxy]carbonyl}-2,2-dimethylcyclopropyl)prop-2-enoic acid (2Z)-3-(3-{[cyano(3-phenoxyphenyl)methoxy]carbonyl}-2,2-dimethylcyclopropyl)prop-2-enoic acid Acrinathrin C23H21NO5 OC(=O)/C=C\C3C(C(=O)OC(C#N)c2cccc(Oc1ccccc1)c2)C3(C)C InChI=1/C23H21NO5/c1-23(2)18(11-12-20(25)26)21(23)22(27)29-19(14-24)15-7-6-10-17(13-15)28-16-8-4-3-5-9-16/h3-13,18-19,21H,1-2H3,(H,25,26)/b12-11- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: France Acrinathrin (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin. 19Dec2013 2013 doi:10.2903/j.efsa.2013.3469
+Acrinathrin 101007-06-1 single chemical entity Component is a metabolite of the substance 3-[(Z)-2-carboxyethenyl]-2,2-dimethylcyclopropanecarboxylic acid 3-[(Z)-2-carboxyethenyl]-2,2-dimethylcyclopropanecarboxylic acid Acrinathrin C9H12O4 OC(=O)/C=C\C1C(C(=O)O)C1(C)C InChI=1/C9H12O4/c1-9(2)5(3-4-6(10)11)7(9)8(12)13/h3-5,7H,1-2H3,(H,10,11)(H,12,13)/b4-3- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: France Acrinathrin (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin. 19Dec2013 2013 doi:10.2903/j.efsa.2013.3469
+Acrinathrin 101007-06-1 single chemical entity Component is a metabolite of the substance 3-[(Z)-2-carboxyethenyl]-2,2-dimethylcyclopropanecarboxylic acid 3-[(Z)-2-carboxyethenyl]-2,2-dimethylcyclopropanecarboxylic acid Acrinathrin C9H12O4 OC(=O)/C=C\C1C(C(=O)O)C1(C)C InChI=1/C9H12O4/c1-9(2)5(3-4-6(10)11)7(9)8(12)13/h3-5,7H,1-2H3,(H,10,11)(H,12,13)/b4-3- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: France Acrinathrin (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin. 19Dec2013 2013 doi:10.2903/j.efsa.2013.3469
+Acrinathrin 101007-06-1 single chemical entity Component is a metabolite of the substance 3-[(Z)-2-carboxyethenyl]-2,2-dimethylcyclopropanecarboxylic acid 3-[(Z)-2-carboxyethenyl]-2,2-dimethylcyclopropanecarboxylic acid Acrinathrin C9H12O4 OC(=O)/C=C\C1C(C(=O)O)C1(C)C InChI=1/C9H12O4/c1-9(2)5(3-4-6(10)11)7(9)8(12)13/h3-5,7H,1-2H3,(H,10,11)(H,12,13)/b4-3- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: France Acrinathrin (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin. 19Dec2013 2013 doi:10.2903/j.efsa.2013.3469
+Acrinathrin 101007-06-1 single chemical entity Component is a metabolite of the substance 3-[(Z)-2-carboxyethenyl]-2,2-dimethylcyclopropanecarboxylic acid 3-[(Z)-2-carboxyethenyl]-2,2-dimethylcyclopropanecarboxylic acid Acrinathrin C9H12O4 OC(=O)/C=C\C1C(C(=O)O)C1(C)C InChI=1/C9H12O4/c1-9(2)5(3-4-6(10)11)7(9)8(12)13/h3-5,7H,1-2H3,(H,10,11)(H,12,13)/b4-3- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes with Negative RMS: France Acrinathrin (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin. 19Dec2013 2013 doi:10.2903/j.efsa.2013.3469
+Acrinathrin 101007-06-1 single chemical entity Component is a metabolite of the substance 3-[(Z)-2-carboxyethenyl]-2,2-dimethylcyclopropanecarboxylic acid 3-[(Z)-2-carboxyethenyl]-2,2-dimethylcyclopropanecarboxylic acid Acrinathrin C9H12O4 OC(=O)/C=C\C1C(C(=O)O)C1(C)C InChI=1/C9H12O4/c1-9(2)5(3-4-6(10)11)7(9)8(12)13/h3-5,7H,1-2H3,(H,10,11)(H,12,13)/b4-3- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: France Acrinathrin (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin. 19Dec2013 2013 doi:10.2903/j.efsa.2013.3469
+Acrinathrin 101007-06-1 single chemical entity Component is a metabolite of the substance 3-[(Z)-2-carboxyethenyl]-2,2-dimethylcyclopropanecarboxylic acid 3-[(Z)-2-carboxyethenyl]-2,2-dimethylcyclopropanecarboxylic acid Acrinathrin C9H12O4 OC(=O)/C=C\C1C(C(=O)O)C1(C)C InChI=1/C9H12O4/c1-9(2)5(3-4-6(10)11)7(9)8(12)13/h3-5,7H,1-2H3,(H,10,11)(H,12,13)/b4-3- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: France Acrinathrin (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin. 19Dec2013 2013 doi:10.2903/j.efsa.2013.3469
+Acrinathrin 101007-06-1 single chemical entity Component is a metabolite of the substance 3-[(Z)-2-carboxyethenyl]-2,2-dimethylcyclopropanecarboxylic acid 3-[(Z)-2-carboxyethenyl]-2,2-dimethylcyclopropanecarboxylic acid Acrinathrin C9H12O4 OC(=O)/C=C\C1C(C(=O)O)C1(C)C InChI=1/C9H12O4/c1-9(2)5(3-4-6(10)11)7(9)8(12)13/h3-5,7H,1-2H3,(H,10,11)(H,12,13)/b4-3- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: France Acrinathrin (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin. 19Dec2013 2013 doi:10.2903/j.efsa.2013.3469
+Acrinathrin 101007-06-1 single chemical entity Component is a metabolite of the substance 3-[(Z)-2-carboxyethenyl]-2,2-dimethylcyclopropanecarboxylic acid 3-[(Z)-2-carboxyethenyl]-2,2-dimethylcyclopropanecarboxylic acid Acrinathrin C9H12O4 OC(=O)/C=C\C1C(C(=O)O)C1(C)C InChI=1/C9H12O4/c1-9(2)5(3-4-6(10)11)7(9)8(12)13/h3-5,7H,1-2H3,(H,10,11)(H,12,13)/b4-3- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: France Acrinathrin (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin. 19Dec2013 2013 doi:10.2903/j.efsa.2013.3469
+Acrinathrin 101007-06-1 single chemical entity Component is a metabolite of the substance 3-[(Z)-2-carboxyethenyl]-2,2-dimethylcyclopropanecarboxylic acid 3-[(Z)-2-carboxyethenyl]-2,2-dimethylcyclopropanecarboxylic acid Acrinathrin C9H12O4 OC(=O)/C=C\C1C(C(=O)O)C1(C)C InChI=1/C9H12O4/c1-9(2)5(3-4-6(10)11)7(9)8(12)13/h3-5,7H,1-2H3,(H,10,11)(H,12,13)/b4-3- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: France Acrinathrin (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin. 19Dec2013 2013 doi:10.2903/j.efsa.2013.3469
+Acrinathrin 101007-06-1 single chemical entity Component is a metabolite of the substance 3-[(Z)-2-carboxyethenyl]-2,2-dimethylcyclopropanecarboxylic acid 3-[(Z)-2-carboxyethenyl]-2,2-dimethylcyclopropanecarboxylic acid Acrinathrin C9H12O4 OC(=O)/C=C\C1C(C(=O)O)C1(C)C InChI=1/C9H12O4/c1-9(2)5(3-4-6(10)11)7(9)8(12)13/h3-5,7H,1-2H3,(H,10,11)(H,12,13)/b4-3- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: France Acrinathrin (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin. 19Dec2013 2013 doi:10.2903/j.efsa.2013.3469
+Acrinathrin 101007-06-1 single chemical entity Component is a metabolite of the substance 3-[(Z)-2-carboxyethenyl]-2,2-dimethylcyclopropanecarboxylic acid 3-[(Z)-2-carboxyethenyl]-2,2-dimethylcyclopropanecarboxylic acid Acrinathrin C9H12O4 OC(=O)/C=C\C1C(C(=O)O)C1(C)C InChI=1/C9H12O4/c1-9(2)5(3-4-6(10)11)7(9)8(12)13/h3-5,7H,1-2H3,(H,10,11)(H,12,13)/b4-3- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes without Negative RMS: France Acrinathrin (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin. 19Dec2013 2013 doi:10.2903/j.efsa.2013.3469
+Acrinathrin 101007-06-1 single chemical entity Component is a metabolite of the substance 3-[(Z)-2-carboxyethenyl]-2,2-dimethylcyclopropanecarboxylic acid 3-[(Z)-2-carboxyethenyl]-2,2-dimethylcyclopropanecarboxylic acid Acrinathrin C9H12O4 OC(=O)/C=C\C1C(C(=O)O)C1(C)C InChI=1/C9H12O4/c1-9(2)5(3-4-6(10)11)7(9)8(12)13/h3-5,7H,1-2H3,(H,10,11)(H,12,13)/b4-3- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: France Acrinathrin (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin. 19Dec2013 2013 doi:10.2903/j.efsa.2013.3469
+Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 single chemical entity Component is identical to the substance Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 Aluminum;azanium;disulfate;dodecahydrate Aluminium ammonium sulphate dodecahydrate AlH28NO20S2 [NH4+].O.O.O.O.O.O.O.O.O.O.O.O.[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3] InChI=1S/Al.H3N.2H2O4S.12H2O/c;;2*1-5(2,3)4;;;;;;;;;;;;/h;1H3;2*(H2,1,2,3,4);12*1H2/q+3;;;;;;;;;;;;;;;/p-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Portugal Aluminium ammonium sulphate (Final Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate) 15Mar2012 2012 doi:10.2903/j.efsa.2012.2491
+Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 single chemical entity Component is identical to the substance Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 Aluminum;azanium;disulfate;dodecahydrate Aluminium ammonium sulphate dodecahydrate AlH28NO20S2 [NH4+].O.O.O.O.O.O.O.O.O.O.O.O.[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3] InChI=1S/Al.H3N.2H2O4S.12H2O/c;;2*1-5(2,3)4;;;;;;;;;;;;/h;1H3;2*(H2,1,2,3,4);12*1H2/q+3;;;;;;;;;;;;;;;/p-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Portugal Aluminium ammonium sulphate (Final Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate) 15Mar2012 2012 doi:10.2903/j.efsa.2012.2491
+Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 single chemical entity Component is identical to the substance Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 Aluminum;azanium;disulfate;dodecahydrate Aluminium ammonium sulphate dodecahydrate AlH28NO20S2 [NH4+].O.O.O.O.O.O.O.O.O.O.O.O.[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3] InChI=1S/Al.H3N.2H2O4S.12H2O/c;;2*1-5(2,3)4;;;;;;;;;;;;/h;1H3;2*(H2,1,2,3,4);12*1H2/q+3;;;;;;;;;;;;;;;/p-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Portugal Aluminium ammonium sulphate (Final Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate) 15Mar2012 2012 doi:10.2903/j.efsa.2012.2491
+Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 single chemical entity Component is identical to the substance Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 Aluminum;azanium;disulfate;dodecahydrate Aluminium ammonium sulphate dodecahydrate AlH28NO20S2 [NH4+].O.O.O.O.O.O.O.O.O.O.O.O.[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3] InChI=1S/Al.H3N.2H2O4S.12H2O/c;;2*1-5(2,3)4;;;;;;;;;;;;/h;1H3;2*(H2,1,2,3,4);12*1H2/q+3;;;;;;;;;;;;;;;/p-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Portugal Aluminium ammonium sulphate (Final Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate) 15Mar2012 2012 doi:10.2903/j.efsa.2012.2491
+Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 single chemical entity Component is identical to the substance Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 Aluminum;azanium;disulfate;dodecahydrate Aluminium ammonium sulphate dodecahydrate AlH28NO20S2 [NH4+].O.O.O.O.O.O.O.O.O.O.O.O.[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3] InChI=1S/Al.H3N.2H2O4S.12H2O/c;;2*1-5(2,3)4;;;;;;;;;;;;/h;1H3;2*(H2,1,2,3,4);12*1H2/q+3;;;;;;;;;;;;;;;/p-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes without Negative RMS: Portugal Aluminium ammonium sulphate (Final Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate) 15Mar2012 2012 doi:10.2903/j.efsa.2012.2491
+Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 single chemical entity Component is identical to the substance Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 Aluminum;azanium;disulfate;dodecahydrate Aluminium ammonium sulphate dodecahydrate AlH28NO20S2 [NH4+].O.O.O.O.O.O.O.O.O.O.O.O.[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3] InChI=1S/Al.H3N.2H2O4S.12H2O/c;;2*1-5(2,3)4;;;;;;;;;;;;/h;1H3;2*(H2,1,2,3,4);12*1H2/q+3;;;;;;;;;;;;;;;/p-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Portugal Aluminium ammonium sulphate (Final Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate) 15Mar2012 2012 doi:10.2903/j.efsa.2012.2491
+Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 single chemical entity Component is identical to the substance Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 Aluminum;azanium;disulfate;dodecahydrate Aluminium ammonium sulphate dodecahydrate AlH28NO20S2 [NH4+].O.O.O.O.O.O.O.O.O.O.O.O.[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3] InChI=1S/Al.H3N.2H2O4S.12H2O/c;;2*1-5(2,3)4;;;;;;;;;;;;/h;1H3;2*(H2,1,2,3,4);12*1H2/q+3;;;;;;;;;;;;;;;/p-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Portugal Aluminium ammonium sulphate (Final Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate) 15Mar2012 2012 doi:10.2903/j.efsa.2012.2491
+Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 single chemical entity Component is identical to the substance Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 Aluminum;azanium;disulfate;dodecahydrate Aluminium ammonium sulphate dodecahydrate AlH28NO20S2 [NH4+].O.O.O.O.O.O.O.O.O.O.O.O.[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3] InChI=1S/Al.H3N.2H2O4S.12H2O/c;;2*1-5(2,3)4;;;;;;;;;;;;/h;1H3;2*(H2,1,2,3,4);12*1H2/q+3;;;;;;;;;;;;;;;/p-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes with Negative RMS: Portugal Aluminium ammonium sulphate (Final Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate) 15Mar2012 2012 doi:10.2903/j.efsa.2012.2491
+Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 single chemical entity Component is identical to the substance Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 Aluminum;azanium;disulfate;dodecahydrate Aluminium ammonium sulphate dodecahydrate AlH28NO20S2 [NH4+].O.O.O.O.O.O.O.O.O.O.O.O.[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3] InChI=1S/Al.H3N.2H2O4S.12H2O/c;;2*1-5(2,3)4;;;;;;;;;;;;/h;1H3;2*(H2,1,2,3,4);12*1H2/q+3;;;;;;;;;;;;;;;/p-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Portugal Aluminium ammonium sulphate (Final Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate) 15Mar2012 2012 doi:10.2903/j.efsa.2012.2491
+Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 single chemical entity Component is identical to the substance Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 Aluminum;azanium;disulfate;dodecahydrate Aluminium ammonium sulphate dodecahydrate AlH28NO20S2 [NH4+].O.O.O.O.O.O.O.O.O.O.O.O.[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3] InChI=1S/Al.H3N.2H2O4S.12H2O/c;;2*1-5(2,3)4;;;;;;;;;;;;/h;1H3;2*(H2,1,2,3,4);12*1H2/q+3;;;;;;;;;;;;;;;/p-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Portugal Aluminium ammonium sulphate (Final Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate) 15Mar2012 2012 doi:10.2903/j.efsa.2012.2491
+Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 single chemical entity Component is identical to the substance Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 Aluminum;azanium;disulfate;dodecahydrate Aluminium ammonium sulphate dodecahydrate AlH28NO20S2 [NH4+].O.O.O.O.O.O.O.O.O.O.O.O.[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3] InChI=1S/Al.H3N.2H2O4S.12H2O/c;;2*1-5(2,3)4;;;;;;;;;;;;/h;1H3;2*(H2,1,2,3,4);12*1H2/q+3;;;;;;;;;;;;;;;/p-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes with Negative RMS: Portugal Aluminium ammonium sulphate (Final Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate) 15Mar2012 2012 doi:10.2903/j.efsa.2012.2491
+Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 single chemical entity Component is identical to the substance Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 Aluminum;azanium;disulfate;dodecahydrate Aluminium ammonium sulphate dodecahydrate AlH28NO20S2 [NH4+].O.O.O.O.O.O.O.O.O.O.O.O.[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3] InChI=1S/Al.H3N.2H2O4S.12H2O/c;;2*1-5(2,3)4;;;;;;;;;;;;/h;1H3;2*(H2,1,2,3,4);12*1H2/q+3;;;;;;;;;;;;;;;/p-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Portugal Aluminium ammonium sulphate (Final Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate) 15Mar2012 2012 doi:10.2903/j.efsa.2012.2491
+Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 single chemical entity Component is identical to the substance Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 Aluminum;azanium;disulfate;dodecahydrate Aluminium ammonium sulphate dodecahydrate AlH28NO20S2 [NH4+].O.O.O.O.O.O.O.O.O.O.O.O.[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3] InChI=1S/Al.H3N.2H2O4S.12H2O/c;;2*1-5(2,3)4;;;;;;;;;;;;/h;1H3;2*(H2,1,2,3,4);12*1H2/q+3;;;;;;;;;;;;;;;/p-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Portugal Aluminium ammonium sulphate (Final Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate) 15Mar2012 2012 doi:10.2903/j.efsa.2012.2491
+Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 single chemical entity Component is identical to the substance Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 Aluminum;azanium;disulfate;dodecahydrate Aluminium ammonium sulphate dodecahydrate AlH28NO20S2 [NH4+].O.O.O.O.O.O.O.O.O.O.O.O.[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3] InChI=1S/Al.H3N.2H2O4S.12H2O/c;;2*1-5(2,3)4;;;;;;;;;;;;/h;1H3;2*(H2,1,2,3,4);12*1H2/q+3;;;;;;;;;;;;;;;/p-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Portugal Aluminium ammonium sulphate (Final Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate) 15Mar2012 2012 doi:10.2903/j.efsa.2012.2491
+Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 single chemical entity Component is identical to the substance Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 Aluminum;azanium;disulfate;dodecahydrate Aluminium ammonium sulphate dodecahydrate AlH28NO20S2 [NH4+].O.O.O.O.O.O.O.O.O.O.O.O.[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3] InChI=1S/Al.H3N.2H2O4S.12H2O/c;;2*1-5(2,3)4;;;;;;;;;;;;/h;1H3;2*(H2,1,2,3,4);12*1H2/q+3;;;;;;;;;;;;;;;/p-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Portugal Aluminium ammonium sulphate (Final Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate) 15Mar2012 2012 doi:10.2903/j.efsa.2012.2491
+Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 single chemical entity Component is identical to the substance Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 Aluminum;azanium;disulfate;dodecahydrate Aluminium ammonium sulphate dodecahydrate AlH28NO20S2 [NH4+].O.O.O.O.O.O.O.O.O.O.O.O.[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3] InChI=1S/Al.H3N.2H2O4S.12H2O/c;;2*1-5(2,3)4;;;;;;;;;;;;/h;1H3;2*(H2,1,2,3,4);12*1H2/q+3;;;;;;;;;;;;;;;/p-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Portugal Aluminium ammonium sulphate (Final Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate) 15Mar2012 2012 doi:10.2903/j.efsa.2012.2491
+Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 single chemical entity Component is identical to the substance Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 Aluminum;azanium;disulfate;dodecahydrate Aluminium ammonium sulphate dodecahydrate AlH28NO20S2 [NH4+].O.O.O.O.O.O.O.O.O.O.O.O.[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3] InChI=1S/Al.H3N.2H2O4S.12H2O/c;;2*1-5(2,3)4;;;;;;;;;;;;/h;1H3;2*(H2,1,2,3,4);12*1H2/q+3;;;;;;;;;;;;;;;/p-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Portugal Aluminium ammonium sulphate (Final Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate) 15Mar2012 2012 doi:10.2903/j.efsa.2012.2491
+Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 single chemical entity Component is identical to the substance Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 Aluminum;azanium;disulfate;dodecahydrate Aluminium ammonium sulphate dodecahydrate AlH28NO20S2 [NH4+].O.O.O.O.O.O.O.O.O.O.O.O.[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3] InChI=1S/Al.H3N.2H2O4S.12H2O/c;;2*1-5(2,3)4;;;;;;;;;;;;/h;1H3;2*(H2,1,2,3,4);12*1H2/q+3;;;;;;;;;;;;;;;/p-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Portugal Aluminium ammonium sulphate (Final Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate) 15Mar2012 2012 doi:10.2903/j.efsa.2012.2491
+Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 single chemical entity Component is identical to the substance Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 Aluminum;azanium;disulfate;dodecahydrate Aluminium ammonium sulphate dodecahydrate AlH28NO20S2 [NH4+].O.O.O.O.O.O.O.O.O.O.O.O.[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3] InChI=1S/Al.H3N.2H2O4S.12H2O/c;;2*1-5(2,3)4;;;;;;;;;;;;/h;1H3;2*(H2,1,2,3,4);12*1H2/q+3;;;;;;;;;;;;;;;/p-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes without Negative RMS: Portugal Aluminium ammonium sulphate (Final Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate) 15Mar2012 2012 doi:10.2903/j.efsa.2012.2491
+Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 single chemical entity Component is identical to the substance Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 Aluminum;azanium;disulfate;dodecahydrate Aluminium ammonium sulphate dodecahydrate AlH28NO20S2 [NH4+].O.O.O.O.O.O.O.O.O.O.O.O.[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3] InChI=1S/Al.H3N.2H2O4S.12H2O/c;;2*1-5(2,3)4;;;;;;;;;;;;/h;1H3;2*(H2,1,2,3,4);12*1H2/q+3;;;;;;;;;;;;;;;/p-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Portugal Aluminium ammonium sulphate (Final Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate) 15Mar2012 2012 doi:10.2903/j.efsa.2012.2491
+Aluminium phosphide 244-088-0 20859-73-8 single chemical entity Component is part of a group but not included in the group assessment Magnesium phosphide 235-023-7 12057-74-8 Trimagnesium;phosphorus(3-) Not in list Mg3P2 [Mg+2].[Mg+2].[Mg+2].[P-3].[P-3] InChI=1S/3Mg.2P/q3*+2;2*-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany Aluminium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.182r
+Aluminium phosphide 244-088-0 20859-73-8 single chemical entity Component is part of a group but not included in the group assessment Magnesium phosphide 235-023-7 12057-74-8 Trimagnesium;phosphorus(3-) Not in list Mg3P2 [Mg+2].[Mg+2].[Mg+2].[P-3].[P-3] InChI=1S/3Mg.2P/q3*+2;2*-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany Aluminium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.182r
+Aluminium phosphide 244-088-0 20859-73-8 single chemical entity Component is part of a group but not included in the group assessment Magnesium phosphide 235-023-7 12057-74-8 Trimagnesium;phosphorus(3-) Not in list Mg3P2 [Mg+2].[Mg+2].[Mg+2].[P-3].[P-3] InChI=1S/3Mg.2P/q3*+2;2*-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle without Negative RMS: Germany Aluminium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.182r
+Aluminium phosphide 244-088-0 20859-73-8 single chemical entity Component is part of a group but not included in the group assessment Magnesium phosphide 235-023-7 12057-74-8 Trimagnesium;phosphorus(3-) Not in list Mg3P2 [Mg+2].[Mg+2].[Mg+2].[P-3].[P-3] InChI=1S/3Mg.2P/q3*+2;2*-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany Aluminium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.182r
+Aluminium phosphide 244-088-0 20859-73-8 single chemical entity Component is part of a group but not included in the group assessment Magnesium phosphide 235-023-7 12057-74-8 Trimagnesium;phosphorus(3-) Not in list Mg3P2 [Mg+2].[Mg+2].[Mg+2].[P-3].[P-3] InChI=1S/3Mg.2P/q3*+2;2*-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Germany Aluminium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.182r
+Aluminium phosphide 244-088-0 20859-73-8 single chemical entity Component is part of a group but not included in the group assessment Magnesium phosphide 235-023-7 12057-74-8 Trimagnesium;phosphorus(3-) Not in list Mg3P2 [Mg+2].[Mg+2].[Mg+2].[P-3].[P-3] InChI=1S/3Mg.2P/q3*+2;2*-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany Aluminium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.182r
+Aluminium phosphide 244-088-0 20859-73-8 single chemical entity Component is part of a group but not included in the group assessment Magnesium phosphide 235-023-7 12057-74-8 Trimagnesium;phosphorus(3-) Not in list Mg3P2 [Mg+2].[Mg+2].[Mg+2].[P-3].[P-3] InChI=1S/3Mg.2P/q3*+2;2*-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Germany Aluminium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.182r
+Aluminium phosphide 244-088-0 20859-73-8 single chemical entity Component is part of a group but not included in the group assessment Magnesium phosphide 235-023-7 12057-74-8 Trimagnesium;phosphorus(3-) Not in list Mg3P2 [Mg+2].[Mg+2].[Mg+2].[P-3].[P-3] InChI=1S/3Mg.2P/q3*+2;2*-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany Aluminium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.182r
+Aluminium phosphide 244-088-0 20859-73-8 single chemical entity Component is part of a group but not included in the group assessment Magnesium phosphide 235-023-7 12057-74-8 Trimagnesium;phosphorus(3-) Not in list Mg3P2 [Mg+2].[Mg+2].[Mg+2].[P-3].[P-3] InChI=1S/3Mg.2P/q3*+2;2*-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany Aluminium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.182r
+Aluminium phosphide 244-088-0 20859-73-8 single chemical entity Component is part of a group but not included in the group assessment Magnesium phosphide 235-023-7 12057-74-8 Trimagnesium;phosphorus(3-) Not in list Mg3P2 [Mg+2].[Mg+2].[Mg+2].[P-3].[P-3] InChI=1S/3Mg.2P/q3*+2;2*-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany Aluminium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.182r
+Aluminium phosphide 244-088-0 20859-73-8 single chemical entity Component is part of a group but not included in the group assessment Magnesium phosphide 235-023-7 12057-74-8 Trimagnesium;phosphorus(3-) Not in list Mg3P2 [Mg+2].[Mg+2].[Mg+2].[P-3].[P-3] InChI=1S/3Mg.2P/q3*+2;2*-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle with Negative RMS: Germany Aluminium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.182r
+Aluminium phosphide 244-088-0 20859-73-8 single chemical entity Component is part of a group but not included in the group assessment Magnesium phosphide 235-023-7 12057-74-8 Trimagnesium;phosphorus(3-) Not in list Mg3P2 [Mg+2].[Mg+2].[Mg+2].[P-3].[P-3] InChI=1S/3Mg.2P/q3*+2;2*-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany Aluminium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.182r
+Calcium phosphide 215-142-0 1305-99-3 single chemical entity Component is part of a group but not included in the group assessment Magnesium phosphide 235-023-7 12057-74-8 Trimagnesium;phosphorus(3-) Not in list Mg3P2 [Mg+2].[Mg+2].[Mg+2].[P-3].[P-3] InChI=1S/3Mg.2P/q3*+2;2*-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Germany Calcium phosphide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide 22Oct2008 2008 doi:10.2903/j.efsa.2008.183r
+Calcium phosphide 215-142-0 1305-99-3 single chemical entity Component is part of a group but not included in the group assessment Magnesium phosphide 235-023-7 12057-74-8 Trimagnesium;phosphorus(3-) Not in list Mg3P2 [Mg+2].[Mg+2].[Mg+2].[P-3].[P-3] InChI=1S/3Mg.2P/q3*+2;2*-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany Calcium phosphide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide 22Oct2008 2008 doi:10.2903/j.efsa.2008.183r
+Calcium phosphide 215-142-0 1305-99-3 single chemical entity Component is part of a group but not included in the group assessment Magnesium phosphide 235-023-7 12057-74-8 Trimagnesium;phosphorus(3-) Not in list Mg3P2 [Mg+2].[Mg+2].[Mg+2].[P-3].[P-3] InChI=1S/3Mg.2P/q3*+2;2*-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany Calcium phosphide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide 22Oct2008 2008 doi:10.2903/j.efsa.2008.183r
+Calcium phosphide 215-142-0 1305-99-3 single chemical entity Component is part of a group but not included in the group assessment Magnesium phosphide 235-023-7 12057-74-8 Trimagnesium;phosphorus(3-) Not in list Mg3P2 [Mg+2].[Mg+2].[Mg+2].[P-3].[P-3] InChI=1S/3Mg.2P/q3*+2;2*-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany Calcium phosphide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide 22Oct2008 2008 doi:10.2903/j.efsa.2008.183r
+Calcium phosphide 215-142-0 1305-99-3 single chemical entity Component is part of a group but not included in the group assessment Magnesium phosphide 235-023-7 12057-74-8 Trimagnesium;phosphorus(3-) Not in list Mg3P2 [Mg+2].[Mg+2].[Mg+2].[P-3].[P-3] InChI=1S/3Mg.2P/q3*+2;2*-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle with Negative RMS: Germany Calcium phosphide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide 22Oct2008 2008 doi:10.2903/j.efsa.2008.183r
+Calcium phosphide 215-142-0 1305-99-3 single chemical entity Component is part of a group but not included in the group assessment Magnesium phosphide 235-023-7 12057-74-8 Trimagnesium;phosphorus(3-) Not in list Mg3P2 [Mg+2].[Mg+2].[Mg+2].[P-3].[P-3] InChI=1S/3Mg.2P/q3*+2;2*-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany Calcium phosphide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide 22Oct2008 2008 doi:10.2903/j.efsa.2008.183r
+Calcium phosphide 215-142-0 1305-99-3 single chemical entity Component is part of a group but not included in the group assessment Magnesium phosphide 235-023-7 12057-74-8 Trimagnesium;phosphorus(3-) Not in list Mg3P2 [Mg+2].[Mg+2].[Mg+2].[P-3].[P-3] InChI=1S/3Mg.2P/q3*+2;2*-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany Calcium phosphide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide 22Oct2008 2008 doi:10.2903/j.efsa.2008.183r
+Calcium phosphide 215-142-0 1305-99-3 single chemical entity Component is part of a group but not included in the group assessment Magnesium phosphide 235-023-7 12057-74-8 Trimagnesium;phosphorus(3-) Not in list Mg3P2 [Mg+2].[Mg+2].[Mg+2].[P-3].[P-3] InChI=1S/3Mg.2P/q3*+2;2*-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle without Negative RMS: Germany Calcium phosphide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide 22Oct2008 2008 doi:10.2903/j.efsa.2008.183r
+Calcium phosphide 215-142-0 1305-99-3 single chemical entity Component is part of a group but not included in the group assessment Magnesium phosphide 235-023-7 12057-74-8 Trimagnesium;phosphorus(3-) Not in list Mg3P2 [Mg+2].[Mg+2].[Mg+2].[P-3].[P-3] InChI=1S/3Mg.2P/q3*+2;2*-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany Calcium phosphide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide 22Oct2008 2008 doi:10.2903/j.efsa.2008.183r
+Calcium phosphide 215-142-0 1305-99-3 single chemical entity Component is part of a group but not included in the group assessment Magnesium phosphide 235-023-7 12057-74-8 Trimagnesium;phosphorus(3-) Not in list Mg3P2 [Mg+2].[Mg+2].[Mg+2].[P-3].[P-3] InChI=1S/3Mg.2P/q3*+2;2*-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany Calcium phosphide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide 22Oct2008 2008 doi:10.2903/j.efsa.2008.183r
+Calcium phosphide 215-142-0 1305-99-3 single chemical entity Component is part of a group but not included in the group assessment Magnesium phosphide 235-023-7 12057-74-8 Trimagnesium;phosphorus(3-) Not in list Mg3P2 [Mg+2].[Mg+2].[Mg+2].[P-3].[P-3] InChI=1S/3Mg.2P/q3*+2;2*-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany Calcium phosphide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide 22Oct2008 2008 doi:10.2903/j.efsa.2008.183r
+Calcium phosphide 215-142-0 1305-99-3 single chemical entity Component is part of a group but not included in the group assessment Magnesium phosphide 235-023-7 12057-74-8 Trimagnesium;phosphorus(3-) Not in list Mg3P2 [Mg+2].[Mg+2].[Mg+2].[P-3].[P-3] InChI=1S/3Mg.2P/q3*+2;2*-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Germany Calcium phosphide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide 22Oct2008 2008 doi:10.2903/j.efsa.2008.183r
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is part of a group but not included in the group assessment Magnesium phosphide 235-023-7 12057-74-8 Trimagnesium;phosphorus(3-) Not in list Mg3P2 [Mg+2].[Mg+2].[Mg+2].[P-3].[P-3] InChI=1S/3Mg.2P/q3*+2;2*-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany Zinc phosphide 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is part of a group but not included in the group assessment Magnesium phosphide 235-023-7 12057-74-8 Trimagnesium;phosphorus(3-) Not in list Mg3P2 [Mg+2].[Mg+2].[Mg+2].[P-3].[P-3] InChI=1S/3Mg.2P/q3*+2;2*-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Germany Zinc phosphide 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Phosphine 232-260-8 7803-51-2 single chemical entity Component is part of a group but not included in the group assessment Magnesium phosphide 235-023-7 12057-74-8 Trimagnesium;phosphorus(3-) Not in list Mg3P2 [Mg+2].[Mg+2].[Mg+2].[P-3].[P-3] InChI=1S/3Mg.2P/q3*+2;2*-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany Phosphane 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane 02Mar2012 2012 doi:10.2903/j.efsa.2012.2595
+Phosphine 232-260-8 7803-51-2 single chemical entity Component is part of a group but not included in the group assessment Magnesium phosphide 235-023-7 12057-74-8 Trimagnesium;phosphorus(3-) Not in list Mg3P2 [Mg+2].[Mg+2].[Mg+2].[P-3].[P-3] InChI=1S/3Mg.2P/q3*+2;2*-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany Phosphane 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane 02Mar2012 2012 doi:10.2903/j.efsa.2012.2595
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is identical to the substance Magnesium phosphide 235-023-7 12057-74-8 Trimagnesium;phosphorus(3-) Not in list Mg3P2 [Mg+2].[Mg+2].[Mg+2].[P-3].[P-3] InChI=1S/3Mg.2P/q3*+2;2*-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle with Negative RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is part of a group but not included in the group assessment Magnesium phosphide 235-023-7 12057-74-8 Trimagnesium;phosphorus(3-) Not in list Mg3P2 [Mg+2].[Mg+2].[Mg+2].[P-3].[P-3] InChI=1S/3Mg.2P/q3*+2;2*-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany Zinc phosphide 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is part of a group but not included in the group assessment Magnesium phosphide 235-023-7 12057-74-8 Trimagnesium;phosphorus(3-) Not in list Mg3P2 [Mg+2].[Mg+2].[Mg+2].[P-3].[P-3] InChI=1S/3Mg.2P/q3*+2;2*-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany Zinc phosphide 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is part of a group but not included in the group assessment Magnesium phosphide 235-023-7 12057-74-8 Trimagnesium;phosphorus(3-) Not in list Mg3P2 [Mg+2].[Mg+2].[Mg+2].[P-3].[P-3] InChI=1S/3Mg.2P/q3*+2;2*-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany Zinc phosphide 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is identical to the substance Magnesium phosphide 235-023-7 12057-74-8 Trimagnesium;phosphorus(3-) Not in list Mg3P2 [Mg+2].[Mg+2].[Mg+2].[P-3].[P-3] InChI=1S/3Mg.2P/q3*+2;2*-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Phosphine 232-260-8 7803-51-2 single chemical entity Component is part of a group but not included in the group assessment Magnesium phosphide 235-023-7 12057-74-8 Trimagnesium;phosphorus(3-) Not in list Mg3P2 [Mg+2].[Mg+2].[Mg+2].[P-3].[P-3] InChI=1S/3Mg.2P/q3*+2;2*-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Germany Phosphane 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane 02Mar2012 2012 doi:10.2903/j.efsa.2012.2595
+Phosphine 232-260-8 7803-51-2 single chemical entity Component is part of a group but not included in the group assessment Magnesium phosphide 235-023-7 12057-74-8 Trimagnesium;phosphorus(3-) Not in list Mg3P2 [Mg+2].[Mg+2].[Mg+2].[P-3].[P-3] InChI=1S/3Mg.2P/q3*+2;2*-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Germany Phosphane 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane 02Mar2012 2012 doi:10.2903/j.efsa.2012.2595
+Phosphine 232-260-8 7803-51-2 single chemical entity Component is part of a group but not included in the group assessment Magnesium phosphide 235-023-7 12057-74-8 Trimagnesium;phosphorus(3-) Not in list Mg3P2 [Mg+2].[Mg+2].[Mg+2].[P-3].[P-3] InChI=1S/3Mg.2P/q3*+2;2*-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle with Negative RMS: Germany Phosphane 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane 02Mar2012 2012 doi:10.2903/j.efsa.2012.2595
+Phosphine 232-260-8 7803-51-2 single chemical entity Component is part of a group but not included in the group assessment Magnesium phosphide 235-023-7 12057-74-8 Trimagnesium;phosphorus(3-) Not in list Mg3P2 [Mg+2].[Mg+2].[Mg+2].[P-3].[P-3] InChI=1S/3Mg.2P/q3*+2;2*-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany Phosphane 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane 02Mar2012 2012 doi:10.2903/j.efsa.2012.2595
+Phosphine 232-260-8 7803-51-2 single chemical entity Component is part of a group but not included in the group assessment Magnesium phosphide 235-023-7 12057-74-8 Trimagnesium;phosphorus(3-) Not in list Mg3P2 [Mg+2].[Mg+2].[Mg+2].[P-3].[P-3] InChI=1S/3Mg.2P/q3*+2;2*-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany Phosphane 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane 02Mar2012 2012 doi:10.2903/j.efsa.2012.2595
+Phosphine 232-260-8 7803-51-2 single chemical entity Component is part of a group but not included in the group assessment Magnesium phosphide 235-023-7 12057-74-8 Trimagnesium;phosphorus(3-) Not in list Mg3P2 [Mg+2].[Mg+2].[Mg+2].[P-3].[P-3] InChI=1S/3Mg.2P/q3*+2;2*-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany Phosphane 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane 02Mar2012 2012 doi:10.2903/j.efsa.2012.2595
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is identical to the substance Magnesium phosphide 235-023-7 12057-74-8 Trimagnesium;phosphorus(3-) Not in list Mg3P2 [Mg+2].[Mg+2].[Mg+2].[P-3].[P-3] InChI=1S/3Mg.2P/q3*+2;2*-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is identical to the substance Magnesium phosphide 235-023-7 12057-74-8 Trimagnesium;phosphorus(3-) Not in list Mg3P2 [Mg+2].[Mg+2].[Mg+2].[P-3].[P-3] InChI=1S/3Mg.2P/q3*+2;2*-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Phosphine 232-260-8 7803-51-2 single chemical entity Component is part of a group but not included in the group assessment Magnesium phosphide 235-023-7 12057-74-8 Trimagnesium;phosphorus(3-) Not in list Mg3P2 [Mg+2].[Mg+2].[Mg+2].[P-3].[P-3] InChI=1S/3Mg.2P/q3*+2;2*-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany Phosphane 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane 02Mar2012 2012 doi:10.2903/j.efsa.2012.2595
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is identical to the substance Magnesium phosphide 235-023-7 12057-74-8 Trimagnesium;phosphorus(3-) Not in list Mg3P2 [Mg+2].[Mg+2].[Mg+2].[P-3].[P-3] InChI=1S/3Mg.2P/q3*+2;2*-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is part of a group but not included in the group assessment Magnesium phosphide 235-023-7 12057-74-8 Trimagnesium;phosphorus(3-) Not in list Mg3P2 [Mg+2].[Mg+2].[Mg+2].[P-3].[P-3] InChI=1S/3Mg.2P/q3*+2;2*-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany Zinc phosphide 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is part of a group but not included in the group assessment Magnesium phosphide 235-023-7 12057-74-8 Trimagnesium;phosphorus(3-) Not in list Mg3P2 [Mg+2].[Mg+2].[Mg+2].[P-3].[P-3] InChI=1S/3Mg.2P/q3*+2;2*-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany Zinc phosphide 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is identical to the substance Magnesium phosphide 235-023-7 12057-74-8 Trimagnesium;phosphorus(3-) Not in list Mg3P2 [Mg+2].[Mg+2].[Mg+2].[P-3].[P-3] InChI=1S/3Mg.2P/q3*+2;2*-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Phosphine 232-260-8 7803-51-2 single chemical entity Component is part of a group but not included in the group assessment Magnesium phosphide 235-023-7 12057-74-8 Trimagnesium;phosphorus(3-) Not in list Mg3P2 [Mg+2].[Mg+2].[Mg+2].[P-3].[P-3] InChI=1S/3Mg.2P/q3*+2;2*-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany Phosphane 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane 02Mar2012 2012 doi:10.2903/j.efsa.2012.2595
+Phosphine 232-260-8 7803-51-2 single chemical entity Component is part of a group but not included in the group assessment Magnesium phosphide 235-023-7 12057-74-8 Trimagnesium;phosphorus(3-) Not in list Mg3P2 [Mg+2].[Mg+2].[Mg+2].[P-3].[P-3] InChI=1S/3Mg.2P/q3*+2;2*-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle without Negative RMS: Germany Phosphane 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane 02Mar2012 2012 doi:10.2903/j.efsa.2012.2595
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is identical to the substance Magnesium phosphide 235-023-7 12057-74-8 Trimagnesium;phosphorus(3-) Not in list Mg3P2 [Mg+2].[Mg+2].[Mg+2].[P-3].[P-3] InChI=1S/3Mg.2P/q3*+2;2*-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is part of a group but not included in the group assessment Magnesium phosphide 235-023-7 12057-74-8 Trimagnesium;phosphorus(3-) Not in list Mg3P2 [Mg+2].[Mg+2].[Mg+2].[P-3].[P-3] InChI=1S/3Mg.2P/q3*+2;2*-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany Zinc phosphide 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is identical to the substance Magnesium phosphide 235-023-7 12057-74-8 Trimagnesium;phosphorus(3-) Not in list Mg3P2 [Mg+2].[Mg+2].[Mg+2].[P-3].[P-3] InChI=1S/3Mg.2P/q3*+2;2*-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is identical to the substance Magnesium phosphide 235-023-7 12057-74-8 Trimagnesium;phosphorus(3-) Not in list Mg3P2 [Mg+2].[Mg+2].[Mg+2].[P-3].[P-3] InChI=1S/3Mg.2P/q3*+2;2*-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is part of a group but not included in the group assessment Magnesium phosphide 235-023-7 12057-74-8 Trimagnesium;phosphorus(3-) Not in list Mg3P2 [Mg+2].[Mg+2].[Mg+2].[P-3].[P-3] InChI=1S/3Mg.2P/q3*+2;2*-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Germany Zinc phosphide 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is identical to the substance Magnesium phosphide 235-023-7 12057-74-8 Trimagnesium;phosphorus(3-) Not in list Mg3P2 [Mg+2].[Mg+2].[Mg+2].[P-3].[P-3] InChI=1S/3Mg.2P/q3*+2;2*-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle without Negative RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is identical to the substance Magnesium phosphide 235-023-7 12057-74-8 Trimagnesium;phosphorus(3-) Not in list Mg3P2 [Mg+2].[Mg+2].[Mg+2].[P-3].[P-3] InChI=1S/3Mg.2P/q3*+2;2*-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is part of a group but not included in the group assessment Magnesium phosphide 235-023-7 12057-74-8 Trimagnesium;phosphorus(3-) Not in list Mg3P2 [Mg+2].[Mg+2].[Mg+2].[P-3].[P-3] InChI=1S/3Mg.2P/q3*+2;2*-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle without Negative RMS: Germany Zinc phosphide 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is part of a group but not included in the group assessment Magnesium phosphide 235-023-7 12057-74-8 Trimagnesium;phosphorus(3-) Not in list Mg3P2 [Mg+2].[Mg+2].[Mg+2].[P-3].[P-3] InChI=1S/3Mg.2P/q3*+2;2*-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle with Negative RMS: Germany Zinc phosphide 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is identical to the substance Magnesium phosphide 235-023-7 12057-74-8 Trimagnesium;phosphorus(3-) Not in list Mg3P2 [Mg+2].[Mg+2].[Mg+2].[P-3].[P-3] InChI=1S/3Mg.2P/q3*+2;2*-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Phosphine 232-260-8 7803-51-2 single chemical entity Component is part of a group but not included in the group assessment Magnesium phosphide 235-023-7 12057-74-8 Trimagnesium;phosphorus(3-) Not in list Mg3P2 [Mg+2].[Mg+2].[Mg+2].[P-3].[P-3] InChI=1S/3Mg.2P/q3*+2;2*-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany Phosphane 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane 02Mar2012 2012 doi:10.2903/j.efsa.2012.2595
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is part of a group but not included in the group assessment Magnesium phosphide 235-023-7 12057-74-8 Trimagnesium;phosphorus(3-) Not in list Mg3P2 [Mg+2].[Mg+2].[Mg+2].[P-3].[P-3] InChI=1S/3Mg.2P/q3*+2;2*-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany Zinc phosphide 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes with Negative RMS: Germany Zinc phosphide 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Germany Zinc phosphide 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Phosphine 232-260-8 7803-51-2 single chemical entity Component is identical to the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Germany Phosphane 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane 02Mar2012 2012 doi:10.2903/j.efsa.2012.2595
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Germany Zinc phosphide 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Phosphine 232-260-8 7803-51-2 single chemical entity Component is identical to the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Germany Phosphane 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane 02Mar2012 2012 doi:10.2903/j.efsa.2012.2595
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Phosphine 232-260-8 7803-51-2 single chemical entity Component is identical to the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Germany Phosphane 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane 02Mar2012 2012 doi:10.2903/j.efsa.2012.2595
+Phosphine 232-260-8 7803-51-2 single chemical entity Component is identical to the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes without Negative RMS: Germany Phosphane 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane 02Mar2012 2012 doi:10.2903/j.efsa.2012.2595
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Phosphine 232-260-8 7803-51-2 single chemical entity Component is identical to the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Germany Phosphane 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane 02Mar2012 2012 doi:10.2903/j.efsa.2012.2595
+Phosphine 232-260-8 7803-51-2 single chemical entity Component is identical to the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: Germany Phosphane 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane 02Mar2012 2012 doi:10.2903/j.efsa.2012.2595
+Phosphine 232-260-8 7803-51-2 single chemical entity Component is identical to the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Germany Phosphane 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane 02Mar2012 2012 doi:10.2903/j.efsa.2012.2595
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Phosphine 232-260-8 7803-51-2 single chemical entity Component is identical to the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Germany Phosphane 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane 02Mar2012 2012 doi:10.2903/j.efsa.2012.2595
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Germany Zinc phosphide 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Phosphine 232-260-8 7803-51-2 single chemical entity Component is identical to the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes with Negative RMS: Germany Phosphane 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane 02Mar2012 2012 doi:10.2903/j.efsa.2012.2595
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Germany Zinc phosphide 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes without Negative RMS: Germany Zinc phosphide 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Phosphine 232-260-8 7803-51-2 single chemical entity Component is identical to the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Germany Phosphane 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane 02Mar2012 2012 doi:10.2903/j.efsa.2012.2595
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Phosphine 232-260-8 7803-51-2 single chemical entity Component is identical to the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Germany Phosphane 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane 02Mar2012 2012 doi:10.2903/j.efsa.2012.2595
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes with Negative RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: Germany Zinc phosphide 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Phosphine 232-260-8 7803-51-2 single chemical entity Component is identical to the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: Germany Phosphane 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane 02Mar2012 2012 doi:10.2903/j.efsa.2012.2595
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes without Negative RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Germany Zinc phosphide 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: Germany Zinc phosphide 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Germany Zinc phosphide 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Germany Zinc phosphide 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Germany Zinc phosphide 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Calcium phosphide 215-142-0 1305-99-3 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: Germany Calcium phosphide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide 22Oct2008 2008 doi:10.2903/j.efsa.2008.183r
+Calcium phosphide 215-142-0 1305-99-3 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Germany Calcium phosphide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide 22Oct2008 2008 doi:10.2903/j.efsa.2008.183r
+Calcium phosphide 215-142-0 1305-99-3 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes without Negative RMS: Germany Calcium phosphide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide 22Oct2008 2008 doi:10.2903/j.efsa.2008.183r
+Calcium phosphide 215-142-0 1305-99-3 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: Germany Calcium phosphide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide 22Oct2008 2008 doi:10.2903/j.efsa.2008.183r
+Calcium phosphide 215-142-0 1305-99-3 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Germany Calcium phosphide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide 22Oct2008 2008 doi:10.2903/j.efsa.2008.183r
+Calcium phosphide 215-142-0 1305-99-3 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Germany Calcium phosphide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide 22Oct2008 2008 doi:10.2903/j.efsa.2008.183r
+Calcium phosphide 215-142-0 1305-99-3 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Germany Calcium phosphide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide 22Oct2008 2008 doi:10.2903/j.efsa.2008.183r
+Calcium phosphide 215-142-0 1305-99-3 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Germany Calcium phosphide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide 22Oct2008 2008 doi:10.2903/j.efsa.2008.183r
+Calcium phosphide 215-142-0 1305-99-3 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Germany Calcium phosphide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide 22Oct2008 2008 doi:10.2903/j.efsa.2008.183r
+Calcium phosphide 215-142-0 1305-99-3 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Germany Calcium phosphide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide 22Oct2008 2008 doi:10.2903/j.efsa.2008.183r
+Calcium phosphide 215-142-0 1305-99-3 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Germany Calcium phosphide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide 22Oct2008 2008 doi:10.2903/j.efsa.2008.183r
+Calcium phosphide 215-142-0 1305-99-3 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes with Negative RMS: Germany Calcium phosphide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide 22Oct2008 2008 doi:10.2903/j.efsa.2008.183r
+Aluminium phosphide 244-088-0 20859-73-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Germany Aluminium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.182r
+Aluminium phosphide 244-088-0 20859-73-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes with Negative RMS: Germany Aluminium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.182r
+Aluminium phosphide 244-088-0 20859-73-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Germany Aluminium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.182r
+Aluminium phosphide 244-088-0 20859-73-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Germany Aluminium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.182r
+Aluminium phosphide 244-088-0 20859-73-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: Germany Aluminium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.182r
+Aluminium phosphide 244-088-0 20859-73-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Germany Aluminium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.182r
+Aluminium phosphide 244-088-0 20859-73-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Germany Aluminium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.182r
+Aluminium phosphide 244-088-0 20859-73-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Germany Aluminium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.182r
+Aluminium phosphide 244-088-0 20859-73-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes without Negative RMS: Germany Aluminium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.182r
+Aluminium phosphide 244-088-0 20859-73-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: Germany Aluminium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.182r
+Aluminium phosphide 244-088-0 20859-73-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Germany Aluminium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.182r
+Aluminium phosphide 244-088-0 20859-73-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Germany Aluminium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.182r
+Aluminium phosphide 244-088-0 20859-73-8 single chemical entity Component is identical to the substance Aluminium phosphide 244-088-0 20859-73-8 phosphinidyne aluminum Not in list AlP [Al]#P InChI=1/Al.P/rAlP/c1-2 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Germany Aluminium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.182r
+Aluminium phosphide 244-088-0 20859-73-8 single chemical entity Component is identical to the substance Aluminium phosphide 244-088-0 20859-73-8 phosphinidyne aluminum Not in list AlP [Al]#P InChI=1/Al.P/rAlP/c1-2 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes with Negative RMS: Germany Aluminium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.182r
+Aluminium phosphide 244-088-0 20859-73-8 single chemical entity Component is identical to the substance Aluminium phosphide 244-088-0 20859-73-8 phosphinidyne aluminum Not in list AlP [Al]#P InChI=1/Al.P/rAlP/c1-2 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes without Negative RMS: Germany Aluminium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.182r
+Aluminium phosphide 244-088-0 20859-73-8 single chemical entity Component is identical to the substance Aluminium phosphide 244-088-0 20859-73-8 phosphinidyne aluminum Not in list AlP [Al]#P InChI=1/Al.P/rAlP/c1-2 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Germany Aluminium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.182r
+Aluminium phosphide 244-088-0 20859-73-8 single chemical entity Component is identical to the substance Aluminium phosphide 244-088-0 20859-73-8 phosphinidyne aluminum Not in list AlP [Al]#P InChI=1/Al.P/rAlP/c1-2 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Germany Aluminium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.182r
+Aluminium phosphide 244-088-0 20859-73-8 single chemical entity Component is identical to the substance Aluminium phosphide 244-088-0 20859-73-8 phosphinidyne aluminum Not in list AlP [Al]#P InChI=1/Al.P/rAlP/c1-2 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Germany Aluminium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.182r
+Aluminium phosphide 244-088-0 20859-73-8 single chemical entity Component is identical to the substance Aluminium phosphide 244-088-0 20859-73-8 phosphinidyne aluminum Not in list AlP [Al]#P InChI=1/Al.P/rAlP/c1-2 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Germany Aluminium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.182r
+Aluminium phosphide 244-088-0 20859-73-8 single chemical entity Component is identical to the substance Aluminium phosphide 244-088-0 20859-73-8 phosphinidyne aluminum Not in list AlP [Al]#P InChI=1/Al.P/rAlP/c1-2 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Germany Aluminium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.182r
+Aluminium phosphide 244-088-0 20859-73-8 single chemical entity Component is identical to the substance Aluminium phosphide 244-088-0 20859-73-8 phosphinidyne aluminum Not in list AlP [Al]#P InChI=1/Al.P/rAlP/c1-2 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Germany Aluminium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.182r
+Aluminium phosphide 244-088-0 20859-73-8 single chemical entity Component is identical to the substance Aluminium phosphide 244-088-0 20859-73-8 phosphinidyne aluminum Not in list AlP [Al]#P InChI=1/Al.P/rAlP/c1-2 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Germany Aluminium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.182r
+Calcium phosphide 215-142-0 1305-99-3 single chemical entity Component is part of a group but not included in the group assessment Aluminium phosphide 244-088-0 20859-73-8 phosphinidyne aluminum Not in list AlP [Al]#P InChI=1/Al.P/rAlP/c1-2 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Germany Calcium phosphide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide 22Oct2008 2008 doi:10.2903/j.efsa.2008.183r
+Calcium phosphide 215-142-0 1305-99-3 single chemical entity Component is part of a group but not included in the group assessment Aluminium phosphide 244-088-0 20859-73-8 phosphinidyne aluminum Not in list AlP [Al]#P InChI=1/Al.P/rAlP/c1-2 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Germany Calcium phosphide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide 22Oct2008 2008 doi:10.2903/j.efsa.2008.183r
+Calcium phosphide 215-142-0 1305-99-3 single chemical entity Component is part of a group but not included in the group assessment Aluminium phosphide 244-088-0 20859-73-8 phosphinidyne aluminum Not in list AlP [Al]#P InChI=1/Al.P/rAlP/c1-2 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Germany Calcium phosphide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide 22Oct2008 2008 doi:10.2903/j.efsa.2008.183r
+Calcium phosphide 215-142-0 1305-99-3 single chemical entity Component is part of a group but not included in the group assessment Aluminium phosphide 244-088-0 20859-73-8 phosphinidyne aluminum Not in list AlP [Al]#P InChI=1/Al.P/rAlP/c1-2 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Germany Calcium phosphide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide 22Oct2008 2008 doi:10.2903/j.efsa.2008.183r
+Calcium phosphide 215-142-0 1305-99-3 single chemical entity Component is part of a group but not included in the group assessment Aluminium phosphide 244-088-0 20859-73-8 phosphinidyne aluminum Not in list AlP [Al]#P InChI=1/Al.P/rAlP/c1-2 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes with Negative RMS: Germany Calcium phosphide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide 22Oct2008 2008 doi:10.2903/j.efsa.2008.183r
+Calcium phosphide 215-142-0 1305-99-3 single chemical entity Component is part of a group but not included in the group assessment Aluminium phosphide 244-088-0 20859-73-8 phosphinidyne aluminum Not in list AlP [Al]#P InChI=1/Al.P/rAlP/c1-2 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes without Negative RMS: Germany Calcium phosphide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide 22Oct2008 2008 doi:10.2903/j.efsa.2008.183r
+Calcium phosphide 215-142-0 1305-99-3 single chemical entity Component is part of a group but not included in the group assessment Aluminium phosphide 244-088-0 20859-73-8 phosphinidyne aluminum Not in list AlP [Al]#P InChI=1/Al.P/rAlP/c1-2 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Germany Calcium phosphide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide 22Oct2008 2008 doi:10.2903/j.efsa.2008.183r
+Calcium phosphide 215-142-0 1305-99-3 single chemical entity Component is part of a group but not included in the group assessment Aluminium phosphide 244-088-0 20859-73-8 phosphinidyne aluminum Not in list AlP [Al]#P InChI=1/Al.P/rAlP/c1-2 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Germany Calcium phosphide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide 22Oct2008 2008 doi:10.2903/j.efsa.2008.183r
+Calcium phosphide 215-142-0 1305-99-3 single chemical entity Component is part of a group but not included in the group assessment Aluminium phosphide 244-088-0 20859-73-8 phosphinidyne aluminum Not in list AlP [Al]#P InChI=1/Al.P/rAlP/c1-2 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Germany Calcium phosphide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide 22Oct2008 2008 doi:10.2903/j.efsa.2008.183r
+Calcium phosphide 215-142-0 1305-99-3 single chemical entity Component is part of a group but not included in the group assessment Aluminium phosphide 244-088-0 20859-73-8 phosphinidyne aluminum Not in list AlP [Al]#P InChI=1/Al.P/rAlP/c1-2 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Germany Calcium phosphide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide 22Oct2008 2008 doi:10.2903/j.efsa.2008.183r
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is part of a group but not included in the group assessment Aluminium phosphide 244-088-0 20859-73-8 phosphinidyne aluminum Not in list AlP [Al]#P InChI=1/Al.P/rAlP/c1-2 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Germany Zinc phosphide 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Phosphine 232-260-8 7803-51-2 single chemical entity Component is part of a group but not included in the group assessment Aluminium phosphide 244-088-0 20859-73-8 phosphinidyne aluminum Not in list AlP [Al]#P InChI=1/Al.P/rAlP/c1-2 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Germany Phosphane 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane 02Mar2012 2012 doi:10.2903/j.efsa.2012.2595
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is part of a group but not included in the group assessment Aluminium phosphide 244-088-0 20859-73-8 phosphinidyne aluminum Not in list AlP [Al]#P InChI=1/Al.P/rAlP/c1-2 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is part of a group but not included in the group assessment Aluminium phosphide 244-088-0 20859-73-8 phosphinidyne aluminum Not in list AlP [Al]#P InChI=1/Al.P/rAlP/c1-2 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is part of a group but not included in the group assessment Aluminium phosphide 244-088-0 20859-73-8 phosphinidyne aluminum Not in list AlP [Al]#P InChI=1/Al.P/rAlP/c1-2 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes without Negative RMS: Germany Zinc phosphide 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Phosphine 232-260-8 7803-51-2 single chemical entity Component is part of a group but not included in the group assessment Aluminium phosphide 244-088-0 20859-73-8 phosphinidyne aluminum Not in list AlP [Al]#P InChI=1/Al.P/rAlP/c1-2 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes with Negative RMS: Germany Phosphane 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane 02Mar2012 2012 doi:10.2903/j.efsa.2012.2595
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is part of a group but not included in the group assessment Aluminium phosphide 244-088-0 20859-73-8 phosphinidyne aluminum Not in list AlP [Al]#P InChI=1/Al.P/rAlP/c1-2 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Germany Zinc phosphide 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is part of a group but not included in the group assessment Aluminium phosphide 244-088-0 20859-73-8 phosphinidyne aluminum Not in list AlP [Al]#P InChI=1/Al.P/rAlP/c1-2 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Germany Zinc phosphide 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is part of a group but not included in the group assessment Aluminium phosphide 244-088-0 20859-73-8 phosphinidyne aluminum Not in list AlP [Al]#P InChI=1/Al.P/rAlP/c1-2 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is part of a group but not included in the group assessment Aluminium phosphide 244-088-0 20859-73-8 phosphinidyne aluminum Not in list AlP [Al]#P InChI=1/Al.P/rAlP/c1-2 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Phosphine 232-260-8 7803-51-2 single chemical entity Component is part of a group but not included in the group assessment Aluminium phosphide 244-088-0 20859-73-8 phosphinidyne aluminum Not in list AlP [Al]#P InChI=1/Al.P/rAlP/c1-2 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes without Negative RMS: Germany Phosphane 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane 02Mar2012 2012 doi:10.2903/j.efsa.2012.2595
+Phosphine 232-260-8 7803-51-2 single chemical entity Component is part of a group but not included in the group assessment Aluminium phosphide 244-088-0 20859-73-8 phosphinidyne aluminum Not in list AlP [Al]#P InChI=1/Al.P/rAlP/c1-2 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Germany Phosphane 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane 02Mar2012 2012 doi:10.2903/j.efsa.2012.2595
+Phosphine 232-260-8 7803-51-2 single chemical entity Component is part of a group but not included in the group assessment Aluminium phosphide 244-088-0 20859-73-8 phosphinidyne aluminum Not in list AlP [Al]#P InChI=1/Al.P/rAlP/c1-2 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Germany Phosphane 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane 02Mar2012 2012 doi:10.2903/j.efsa.2012.2595
+Phosphine 232-260-8 7803-51-2 single chemical entity Component is part of a group but not included in the group assessment Aluminium phosphide 244-088-0 20859-73-8 phosphinidyne aluminum Not in list AlP [Al]#P InChI=1/Al.P/rAlP/c1-2 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Germany Phosphane 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane 02Mar2012 2012 doi:10.2903/j.efsa.2012.2595
+Phosphine 232-260-8 7803-51-2 single chemical entity Component is part of a group but not included in the group assessment Aluminium phosphide 244-088-0 20859-73-8 phosphinidyne aluminum Not in list AlP [Al]#P InChI=1/Al.P/rAlP/c1-2 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Germany Phosphane 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane 02Mar2012 2012 doi:10.2903/j.efsa.2012.2595
+Phosphine 232-260-8 7803-51-2 single chemical entity Component is part of a group but not included in the group assessment Aluminium phosphide 244-088-0 20859-73-8 phosphinidyne aluminum Not in list AlP [Al]#P InChI=1/Al.P/rAlP/c1-2 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Germany Phosphane 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane 02Mar2012 2012 doi:10.2903/j.efsa.2012.2595
+Phosphine 232-260-8 7803-51-2 single chemical entity Component is part of a group but not included in the group assessment Aluminium phosphide 244-088-0 20859-73-8 phosphinidyne aluminum Not in list AlP [Al]#P InChI=1/Al.P/rAlP/c1-2 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Germany Phosphane 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane 02Mar2012 2012 doi:10.2903/j.efsa.2012.2595
+Phosphine 232-260-8 7803-51-2 single chemical entity Component is part of a group but not included in the group assessment Aluminium phosphide 244-088-0 20859-73-8 phosphinidyne aluminum Not in list AlP [Al]#P InChI=1/Al.P/rAlP/c1-2 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Germany Phosphane 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane 02Mar2012 2012 doi:10.2903/j.efsa.2012.2595
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is part of a group but not included in the group assessment Aluminium phosphide 244-088-0 20859-73-8 phosphinidyne aluminum Not in list AlP [Al]#P InChI=1/Al.P/rAlP/c1-2 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Germany Zinc phosphide 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is part of a group but not included in the group assessment Aluminium phosphide 244-088-0 20859-73-8 phosphinidyne aluminum Not in list AlP [Al]#P InChI=1/Al.P/rAlP/c1-2 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes without Negative RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is part of a group but not included in the group assessment Aluminium phosphide 244-088-0 20859-73-8 phosphinidyne aluminum Not in list AlP [Al]#P InChI=1/Al.P/rAlP/c1-2 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is part of a group but not included in the group assessment Aluminium phosphide 244-088-0 20859-73-8 phosphinidyne aluminum Not in list AlP [Al]#P InChI=1/Al.P/rAlP/c1-2 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is part of a group but not included in the group assessment Aluminium phosphide 244-088-0 20859-73-8 phosphinidyne aluminum Not in list AlP [Al]#P InChI=1/Al.P/rAlP/c1-2 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Germany Zinc phosphide 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is part of a group but not included in the group assessment Aluminium phosphide 244-088-0 20859-73-8 phosphinidyne aluminum Not in list AlP [Al]#P InChI=1/Al.P/rAlP/c1-2 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes with Negative RMS: Germany Zinc phosphide 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is part of a group but not included in the group assessment Aluminium phosphide 244-088-0 20859-73-8 phosphinidyne aluminum Not in list AlP [Al]#P InChI=1/Al.P/rAlP/c1-2 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Germany Zinc phosphide 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is part of a group but not included in the group assessment Aluminium phosphide 244-088-0 20859-73-8 phosphinidyne aluminum Not in list AlP [Al]#P InChI=1/Al.P/rAlP/c1-2 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is part of a group but not included in the group assessment Aluminium phosphide 244-088-0 20859-73-8 phosphinidyne aluminum Not in list AlP [Al]#P InChI=1/Al.P/rAlP/c1-2 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is part of a group but not included in the group assessment Aluminium phosphide 244-088-0 20859-73-8 phosphinidyne aluminum Not in list AlP [Al]#P InChI=1/Al.P/rAlP/c1-2 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Germany Zinc phosphide 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is part of a group but not included in the group assessment Aluminium phosphide 244-088-0 20859-73-8 phosphinidyne aluminum Not in list AlP [Al]#P InChI=1/Al.P/rAlP/c1-2 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Germany Zinc phosphide 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is part of a group but not included in the group assessment Aluminium phosphide 244-088-0 20859-73-8 phosphinidyne aluminum Not in list AlP [Al]#P InChI=1/Al.P/rAlP/c1-2 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes with Negative RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: Germany Zinc phosphide 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Germany Zinc phosphide 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Germany Zinc phosphide 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Phosphine 232-260-8 7803-51-2 single chemical entity Component is identical to the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Germany Phosphane 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane 02Mar2012 2012 doi:10.2903/j.efsa.2012.2595
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: Germany Zinc phosphide 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Phosphine 232-260-8 7803-51-2 single chemical entity Component is identical to the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Germany Phosphane 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane 02Mar2012 2012 doi:10.2903/j.efsa.2012.2595
+Phosphine 232-260-8 7803-51-2 single chemical entity Component is identical to the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Germany Phosphane 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane 02Mar2012 2012 doi:10.2903/j.efsa.2012.2595
+Phosphine 232-260-8 7803-51-2 single chemical entity Component is identical to the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: Germany Phosphane 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane 02Mar2012 2012 doi:10.2903/j.efsa.2012.2595
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Germany Zinc phosphide 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Phosphine 232-260-8 7803-51-2 single chemical entity Component is identical to the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Germany Phosphane 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane 02Mar2012 2012 doi:10.2903/j.efsa.2012.2595
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Germany Zinc phosphide 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Germany Zinc phosphide 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Germany Zinc phosphide 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Phosphine 232-260-8 7803-51-2 single chemical entity Component is identical to the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Germany Phosphane 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane 02Mar2012 2012 doi:10.2903/j.efsa.2012.2595
+Phosphine 232-260-8 7803-51-2 single chemical entity Component is identical to the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: Germany Phosphane 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane 02Mar2012 2012 doi:10.2903/j.efsa.2012.2595
+Phosphine 232-260-8 7803-51-2 single chemical entity Component is identical to the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Germany Phosphane 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane 02Mar2012 2012 doi:10.2903/j.efsa.2012.2595
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Phosphine 232-260-8 7803-51-2 single chemical entity Component is identical to the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Germany Phosphane 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane 02Mar2012 2012 doi:10.2903/j.efsa.2012.2595
+Phosphine 232-260-8 7803-51-2 single chemical entity Component is identical to the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Germany Phosphane 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane 02Mar2012 2012 doi:10.2903/j.efsa.2012.2595
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Germany Zinc phosphide 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Magnesium phosphide 235-023-7 12057-74-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Germany Magnesium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.190r
+Zinc phosphide 215-244-5 1314-84-7 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Germany Zinc phosphide 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide 19Jul2010 2010 doi:10.2903/j.efsa.2010.1671
+Calcium phosphide 215-142-0 1305-99-3 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: Germany Calcium phosphide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide 22Oct2008 2008 doi:10.2903/j.efsa.2008.183r
+Calcium phosphide 215-142-0 1305-99-3 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Germany Calcium phosphide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide 22Oct2008 2008 doi:10.2903/j.efsa.2008.183r
+Calcium phosphide 215-142-0 1305-99-3 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Germany Calcium phosphide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide 22Oct2008 2008 doi:10.2903/j.efsa.2008.183r
+Calcium phosphide 215-142-0 1305-99-3 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Germany Calcium phosphide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide 22Oct2008 2008 doi:10.2903/j.efsa.2008.183r
+Calcium phosphide 215-142-0 1305-99-3 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Germany Calcium phosphide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide 22Oct2008 2008 doi:10.2903/j.efsa.2008.183r
+Calcium phosphide 215-142-0 1305-99-3 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Germany Calcium phosphide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide 22Oct2008 2008 doi:10.2903/j.efsa.2008.183r
+Calcium phosphide 215-142-0 1305-99-3 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Germany Calcium phosphide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide 22Oct2008 2008 doi:10.2903/j.efsa.2008.183r
+Calcium phosphide 215-142-0 1305-99-3 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Germany Calcium phosphide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide 22Oct2008 2008 doi:10.2903/j.efsa.2008.183r
+Calcium phosphide 215-142-0 1305-99-3 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Germany Calcium phosphide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide 22Oct2008 2008 doi:10.2903/j.efsa.2008.183r
+Calcium phosphide 215-142-0 1305-99-3 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: Germany Calcium phosphide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide 22Oct2008 2008 doi:10.2903/j.efsa.2008.183r
+Aluminium phosphide 244-088-0 20859-73-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Germany Aluminium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.182r
+Aluminium phosphide 244-088-0 20859-73-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: Germany Aluminium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.182r
+Aluminium phosphide 244-088-0 20859-73-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Germany Aluminium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.182r
+Aluminium phosphide 244-088-0 20859-73-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Germany Aluminium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.182r
+Aluminium phosphide 244-088-0 20859-73-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Germany Aluminium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.182r
+Aluminium phosphide 244-088-0 20859-73-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Germany Aluminium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.182r
+Aluminium phosphide 244-088-0 20859-73-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Germany Aluminium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.182r
+Aluminium phosphide 244-088-0 20859-73-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Germany Aluminium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.182r
+Aluminium phosphide 244-088-0 20859-73-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: Germany Aluminium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.182r
+Aluminium phosphide 244-088-0 20859-73-8 single chemical entity Component is a metabolite of the substance Phosphine 232-260-8 7803-51-2 phosphine Not in list H3P P InChI=1S/H3P/h1H3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Germany Aluminium phosphide (Final Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide 15Jan2009 2009 doi:10.2903/j.efsa.2009.182r
+Amidosulfuron 120923-37-7 single chemical entity Component is identical to the substance Amidosulfuron 120923-37-7 1-(4,6-dimethoxypyrimidin-2-yl)-3-[methyl(methylsulfonyl)sulfamoyl]urea Amidosulfuron C9H15N5O7S2 O=C(Nc1nc(cc(OC)n1)OC)NS(=O)(=O)N(C)S(C)(=O)=O InChI=1S/C9H15N5O7S2/c1-14(22(4,16)17)23(18,19)13-9(15)12-8-10-6(20-2)5-7(11-8)21-3/h5H,1-4H3,(H2,10,11,12,13,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Austria Amidosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron 09Nov2008 2008 doi:10.2903/j.efsa.2008.116r
+Amidosulfuron 120923-37-7 single chemical entity Component is identical to the substance Amidosulfuron 120923-37-7 1-(4,6-dimethoxypyrimidin-2-yl)-3-[methyl(methylsulfonyl)sulfamoyl]urea Amidosulfuron C9H15N5O7S2 O=C(Nc1nc(cc(OC)n1)OC)NS(=O)(=O)N(C)S(C)(=O)=O InChI=1S/C9H15N5O7S2/c1-14(22(4,16)17)23(18,19)13-9(15)12-8-10-6(20-2)5-7(11-8)21-3/h5H,1-4H3,(H2,10,11,12,13,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Austria Amidosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron 09Nov2008 2008 doi:10.2903/j.efsa.2008.116r
+Amidosulfuron 120923-37-7 single chemical entity Component is identical to the substance Amidosulfuron 120923-37-7 1-(4,6-dimethoxypyrimidin-2-yl)-3-[methyl(methylsulfonyl)sulfamoyl]urea Amidosulfuron C9H15N5O7S2 O=C(Nc1nc(cc(OC)n1)OC)NS(=O)(=O)N(C)S(C)(=O)=O InChI=1S/C9H15N5O7S2/c1-14(22(4,16)17)23(18,19)13-9(15)12-8-10-6(20-2)5-7(11-8)21-3/h5H,1-4H3,(H2,10,11,12,13,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Austria Amidosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron 09Nov2008 2008 doi:10.2903/j.efsa.2008.116r
+Amidosulfuron 120923-37-7 single chemical entity Component is identical to the substance Amidosulfuron 120923-37-7 1-(4,6-dimethoxypyrimidin-2-yl)-3-[methyl(methylsulfonyl)sulfamoyl]urea Amidosulfuron C9H15N5O7S2 O=C(Nc1nc(cc(OC)n1)OC)NS(=O)(=O)N(C)S(C)(=O)=O InChI=1S/C9H15N5O7S2/c1-14(22(4,16)17)23(18,19)13-9(15)12-8-10-6(20-2)5-7(11-8)21-3/h5H,1-4H3,(H2,10,11,12,13,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Austria Amidosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron 09Nov2008 2008 doi:10.2903/j.efsa.2008.116r
+Amidosulfuron 120923-37-7 single chemical entity Component is identical to the substance Amidosulfuron 120923-37-7 1-(4,6-dimethoxypyrimidin-2-yl)-3-[methyl(methylsulfonyl)sulfamoyl]urea Amidosulfuron C9H15N5O7S2 O=C(Nc1nc(cc(OC)n1)OC)NS(=O)(=O)N(C)S(C)(=O)=O InChI=1S/C9H15N5O7S2/c1-14(22(4,16)17)23(18,19)13-9(15)12-8-10-6(20-2)5-7(11-8)21-3/h5H,1-4H3,(H2,10,11,12,13,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Austria Amidosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron 09Nov2008 2008 doi:10.2903/j.efsa.2008.116r
+Amidosulfuron 120923-37-7 single chemical entity Component is identical to the substance Amidosulfuron 120923-37-7 1-(4,6-dimethoxypyrimidin-2-yl)-3-[methyl(methylsulfonyl)sulfamoyl]urea Amidosulfuron C9H15N5O7S2 O=C(Nc1nc(cc(OC)n1)OC)NS(=O)(=O)N(C)S(C)(=O)=O InChI=1S/C9H15N5O7S2/c1-14(22(4,16)17)23(18,19)13-9(15)12-8-10-6(20-2)5-7(11-8)21-3/h5H,1-4H3,(H2,10,11,12,13,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Austria Amidosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron 09Nov2008 2008 doi:10.2903/j.efsa.2008.116r
+Amidosulfuron 120923-37-7 single chemical entity Component is identical to the substance Amidosulfuron 120923-37-7 1-(4,6-dimethoxypyrimidin-2-yl)-3-[methyl(methylsulfonyl)sulfamoyl]urea Amidosulfuron C9H15N5O7S2 O=C(Nc1nc(cc(OC)n1)OC)NS(=O)(=O)N(C)S(C)(=O)=O InChI=1S/C9H15N5O7S2/c1-14(22(4,16)17)23(18,19)13-9(15)12-8-10-6(20-2)5-7(11-8)21-3/h5H,1-4H3,(H2,10,11,12,13,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Austria Amidosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron 09Nov2008 2008 doi:10.2903/j.efsa.2008.116r
+Amidosulfuron 120923-37-7 single chemical entity Component is identical to the substance Amidosulfuron 120923-37-7 1-(4,6-dimethoxypyrimidin-2-yl)-3-[methyl(methylsulfonyl)sulfamoyl]urea Amidosulfuron C9H15N5O7S2 O=C(Nc1nc(cc(OC)n1)OC)NS(=O)(=O)N(C)S(C)(=O)=O InChI=1S/C9H15N5O7S2/c1-14(22(4,16)17)23(18,19)13-9(15)12-8-10-6(20-2)5-7(11-8)21-3/h5H,1-4H3,(H2,10,11,12,13,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Austria Amidosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron 09Nov2008 2008 doi:10.2903/j.efsa.2008.116r
+Amidosulfuron 120923-37-7 single chemical entity Component is identical to the substance Amidosulfuron 120923-37-7 1-(4,6-dimethoxypyrimidin-2-yl)-3-[methyl(methylsulfonyl)sulfamoyl]urea Amidosulfuron C9H15N5O7S2 O=C(Nc1nc(cc(OC)n1)OC)NS(=O)(=O)N(C)S(C)(=O)=O InChI=1S/C9H15N5O7S2/c1-14(22(4,16)17)23(18,19)13-9(15)12-8-10-6(20-2)5-7(11-8)21-3/h5H,1-4H3,(H2,10,11,12,13,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Austria Amidosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron 09Nov2008 2008 doi:10.2903/j.efsa.2008.116r
+Amidosulfuron 120923-37-7 single chemical entity Component is identical to the substance Amidosulfuron 120923-37-7 1-(4,6-dimethoxypyrimidin-2-yl)-3-[methyl(methylsulfonyl)sulfamoyl]urea Amidosulfuron C9H15N5O7S2 O=C(Nc1nc(cc(OC)n1)OC)NS(=O)(=O)N(C)S(C)(=O)=O InChI=1S/C9H15N5O7S2/c1-14(22(4,16)17)23(18,19)13-9(15)12-8-10-6(20-2)5-7(11-8)21-3/h5H,1-4H3,(H2,10,11,12,13,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Austria Amidosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron 09Nov2008 2008 doi:10.2903/j.efsa.2008.116r
+Amidosulfuron 120923-37-7 single chemical entity Component is identical to the substance Amidosulfuron 120923-37-7 1-(4,6-dimethoxypyrimidin-2-yl)-3-[methyl(methylsulfonyl)sulfamoyl]urea Amidosulfuron C9H15N5O7S2 O=C(Nc1nc(cc(OC)n1)OC)NS(=O)(=O)N(C)S(C)(=O)=O InChI=1S/C9H15N5O7S2/c1-14(22(4,16)17)23(18,19)13-9(15)12-8-10-6(20-2)5-7(11-8)21-3/h5H,1-4H3,(H2,10,11,12,13,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Austria Amidosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron 09Nov2008 2008 doi:10.2903/j.efsa.2008.116r
+Amidosulfuron 120923-37-7 single chemical entity Component is identical to the substance Amidosulfuron 120923-37-7 1-(4,6-dimethoxypyrimidin-2-yl)-3-[methyl(methylsulfonyl)sulfamoyl]urea Amidosulfuron C9H15N5O7S2 O=C(Nc1nc(cc(OC)n1)OC)NS(=O)(=O)N(C)S(C)(=O)=O InChI=1S/C9H15N5O7S2/c1-14(22(4,16)17)23(18,19)13-9(15)12-8-10-6(20-2)5-7(11-8)21-3/h5H,1-4H3,(H2,10,11,12,13,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Austria Amidosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron 09Nov2008 2008 doi:10.2903/j.efsa.2008.116r
+Amidosulfuron 120923-37-7 single chemical entity Component is a metabolite of the substance 3-(4-hydroxy-6-methoxypyrimidin-2-yl)-1-(N-methyl-N-methylsulfonylaminosulfonyl)-urea 3-(4-hydroxy-6-methoxypyrimidin-2-yl)-1-(N-methyl-N-methylsulfonylaminosulfonyl)-urea Not in list C8H13N5O7S2 O=C(Nc1nc(O)cc(OC)n1)NS(=O)(=O)N(C)S(C)(=O)=O InChI=1/C8H13N5O7S2/c1-13(21(3,16)17)22(18,19)12-8(15)11-7-9-5(14)4-6(10-7)20-2/h4H,1-3H3,(H3,9,10,11,12,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Austria Amidosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron 09Nov2008 2008 doi:10.2903/j.efsa.2008.116r
+Amidosulfuron 120923-37-7 single chemical entity Component is a metabolite of the substance 3-(4-hydroxy-6-methoxypyrimidin-2-yl)-1-(N-methyl-N-methylsulfonylaminosulfonyl)-urea 3-(4-hydroxy-6-methoxypyrimidin-2-yl)-1-(N-methyl-N-methylsulfonylaminosulfonyl)-urea Not in list C8H13N5O7S2 O=C(Nc1nc(O)cc(OC)n1)NS(=O)(=O)N(C)S(C)(=O)=O InChI=1/C8H13N5O7S2/c1-13(21(3,16)17)22(18,19)12-8(15)11-7-9-5(14)4-6(10-7)20-2/h4H,1-3H3,(H3,9,10,11,12,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Austria Amidosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron 09Nov2008 2008 doi:10.2903/j.efsa.2008.116r
+Amidosulfuron 120923-37-7 single chemical entity Component is a metabolite of the substance 3-(4-hydroxy-6-methoxypyrimidin-2-yl)-1-(N-methyl-N-methylsulfonylaminosulfonyl)-urea 3-(4-hydroxy-6-methoxypyrimidin-2-yl)-1-(N-methyl-N-methylsulfonylaminosulfonyl)-urea Not in list C8H13N5O7S2 O=C(Nc1nc(O)cc(OC)n1)NS(=O)(=O)N(C)S(C)(=O)=O InChI=1/C8H13N5O7S2/c1-13(21(3,16)17)22(18,19)12-8(15)11-7-9-5(14)4-6(10-7)20-2/h4H,1-3H3,(H3,9,10,11,12,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Austria Amidosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron 09Nov2008 2008 doi:10.2903/j.efsa.2008.116r
+Amidosulfuron 120923-37-7 single chemical entity Component is a metabolite of the substance 3-(4-hydroxy-6-methoxypyrimidin-2-yl)-1-(N-methyl-N-methylsulfonylaminosulfonyl)-urea 3-(4-hydroxy-6-methoxypyrimidin-2-yl)-1-(N-methyl-N-methylsulfonylaminosulfonyl)-urea Not in list C8H13N5O7S2 O=C(Nc1nc(O)cc(OC)n1)NS(=O)(=O)N(C)S(C)(=O)=O InChI=1/C8H13N5O7S2/c1-13(21(3,16)17)22(18,19)12-8(15)11-7-9-5(14)4-6(10-7)20-2/h4H,1-3H3,(H3,9,10,11,12,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Austria Amidosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron 09Nov2008 2008 doi:10.2903/j.efsa.2008.116r
+Amidosulfuron 120923-37-7 single chemical entity Component is a metabolite of the substance 3-(4-hydroxy-6-methoxypyrimidin-2-yl)-1-(N-methyl-N-methylsulfonylaminosulfonyl)-urea 3-(4-hydroxy-6-methoxypyrimidin-2-yl)-1-(N-methyl-N-methylsulfonylaminosulfonyl)-urea Not in list C8H13N5O7S2 O=C(Nc1nc(O)cc(OC)n1)NS(=O)(=O)N(C)S(C)(=O)=O InChI=1/C8H13N5O7S2/c1-13(21(3,16)17)22(18,19)12-8(15)11-7-9-5(14)4-6(10-7)20-2/h4H,1-3H3,(H3,9,10,11,12,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Austria Amidosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron 09Nov2008 2008 doi:10.2903/j.efsa.2008.116r
+Amidosulfuron 120923-37-7 single chemical entity Component is a metabolite of the substance 3-(4-hydroxy-6-methoxypyrimidin-2-yl)-1-(N-methyl-N-methylsulfonylaminosulfonyl)-urea 3-(4-hydroxy-6-methoxypyrimidin-2-yl)-1-(N-methyl-N-methylsulfonylaminosulfonyl)-urea Not in list C8H13N5O7S2 O=C(Nc1nc(O)cc(OC)n1)NS(=O)(=O)N(C)S(C)(=O)=O InChI=1/C8H13N5O7S2/c1-13(21(3,16)17)22(18,19)12-8(15)11-7-9-5(14)4-6(10-7)20-2/h4H,1-3H3,(H3,9,10,11,12,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Austria Amidosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron 09Nov2008 2008 doi:10.2903/j.efsa.2008.116r
+Amidosulfuron 120923-37-7 single chemical entity Component is a metabolite of the substance 3-(4-hydroxy-6-methoxypyrimidin-2-yl)-1-(N-methyl-N-methylsulfonylaminosulfonyl)-urea 3-(4-hydroxy-6-methoxypyrimidin-2-yl)-1-(N-methyl-N-methylsulfonylaminosulfonyl)-urea Not in list C8H13N5O7S2 O=C(Nc1nc(O)cc(OC)n1)NS(=O)(=O)N(C)S(C)(=O)=O InChI=1/C8H13N5O7S2/c1-13(21(3,16)17)22(18,19)12-8(15)11-7-9-5(14)4-6(10-7)20-2/h4H,1-3H3,(H3,9,10,11,12,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Austria Amidosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron 09Nov2008 2008 doi:10.2903/j.efsa.2008.116r
+Amidosulfuron 120923-37-7 single chemical entity Component is a metabolite of the substance 3-(4-hydroxy-6-methoxypyrimidin-2-yl)-1-(N-methyl-N-methylsulfonylaminosulfonyl)-urea 3-(4-hydroxy-6-methoxypyrimidin-2-yl)-1-(N-methyl-N-methylsulfonylaminosulfonyl)-urea Not in list C8H13N5O7S2 O=C(Nc1nc(O)cc(OC)n1)NS(=O)(=O)N(C)S(C)(=O)=O InChI=1/C8H13N5O7S2/c1-13(21(3,16)17)22(18,19)12-8(15)11-7-9-5(14)4-6(10-7)20-2/h4H,1-3H3,(H3,9,10,11,12,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Austria Amidosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron 09Nov2008 2008 doi:10.2903/j.efsa.2008.116r
+Amidosulfuron 120923-37-7 single chemical entity Component is a metabolite of the substance 3-(4-hydroxy-6-methoxypyrimidin-2-yl)-1-(N-methyl-N-methylsulfonylaminosulfonyl)-urea 3-(4-hydroxy-6-methoxypyrimidin-2-yl)-1-(N-methyl-N-methylsulfonylaminosulfonyl)-urea Not in list C8H13N5O7S2 O=C(Nc1nc(O)cc(OC)n1)NS(=O)(=O)N(C)S(C)(=O)=O InChI=1/C8H13N5O7S2/c1-13(21(3,16)17)22(18,19)12-8(15)11-7-9-5(14)4-6(10-7)20-2/h4H,1-3H3,(H3,9,10,11,12,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Austria Amidosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron 09Nov2008 2008 doi:10.2903/j.efsa.2008.116r
+Amidosulfuron 120923-37-7 single chemical entity Component is a metabolite of the substance 3-(4-hydroxy-6-methoxypyrimidin-2-yl)-1-(N-methyl-N-methylsulfonylaminosulfonyl)-urea 3-(4-hydroxy-6-methoxypyrimidin-2-yl)-1-(N-methyl-N-methylsulfonylaminosulfonyl)-urea Not in list C8H13N5O7S2 O=C(Nc1nc(O)cc(OC)n1)NS(=O)(=O)N(C)S(C)(=O)=O InChI=1/C8H13N5O7S2/c1-13(21(3,16)17)22(18,19)12-8(15)11-7-9-5(14)4-6(10-7)20-2/h4H,1-3H3,(H3,9,10,11,12,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Austria Amidosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron 09Nov2008 2008 doi:10.2903/j.efsa.2008.116r
+Amidosulfuron 120923-37-7 single chemical entity Component is a metabolite of the substance 3-(4-hydroxy-6-methoxypyrimidin-2-yl)-1-(N-methyl-N-methylsulfonylaminosulfonyl)-urea 3-(4-hydroxy-6-methoxypyrimidin-2-yl)-1-(N-methyl-N-methylsulfonylaminosulfonyl)-urea Not in list C8H13N5O7S2 O=C(Nc1nc(O)cc(OC)n1)NS(=O)(=O)N(C)S(C)(=O)=O InChI=1/C8H13N5O7S2/c1-13(21(3,16)17)22(18,19)12-8(15)11-7-9-5(14)4-6(10-7)20-2/h4H,1-3H3,(H3,9,10,11,12,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Austria Amidosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron 09Nov2008 2008 doi:10.2903/j.efsa.2008.116r
+Amidosulfuron 120923-37-7 single chemical entity Component is a metabolite of the substance 3-(4-hydroxy-6-methoxypyrimidin-2-yl)-1-(N-methyl-N-methylsulfonylaminosulfonyl)-urea 3-(4-hydroxy-6-methoxypyrimidin-2-yl)-1-(N-methyl-N-methylsulfonylaminosulfonyl)-urea Not in list C8H13N5O7S2 O=C(Nc1nc(O)cc(OC)n1)NS(=O)(=O)N(C)S(C)(=O)=O InChI=1/C8H13N5O7S2/c1-13(21(3,16)17)22(18,19)12-8(15)11-7-9-5(14)4-6(10-7)20-2/h4H,1-3H3,(H3,9,10,11,12,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Austria Amidosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron 09Nov2008 2008 doi:10.2903/j.efsa.2008.116r
+Amidosulfuron 120923-37-7 single chemical entity Component is a metabolite of the substance 2-amino-4,6-dihydroxypyrimidine 200-256-5 56-09-7 2-amino-4-hydroxy-1H-pyrimidin-6-one Not in list C4H5N3O2 C1=C(N=C(NC1=O)N)O InChI=1S/C4H5N3O2/c5-4-6-2(8)1-3(9)7-4/h1H,(H4,5,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Austria Amidosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron 09Nov2008 2008 doi:10.2903/j.efsa.2008.116r
+Amidosulfuron 120923-37-7 single chemical entity Component is a metabolite of the substance 2-amino-4,6-dihydroxypyrimidine 200-256-5 56-09-7 2-amino-4-hydroxy-1H-pyrimidin-6-one Not in list C4H5N3O2 C1=C(N=C(NC1=O)N)O InChI=1S/C4H5N3O2/c5-4-6-2(8)1-3(9)7-4/h1H,(H4,5,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Austria Amidosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron 09Nov2008 2008 doi:10.2903/j.efsa.2008.116r
+Amidosulfuron 120923-37-7 single chemical entity Component is a metabolite of the substance 2-amino-4,6-dihydroxypyrimidine 200-256-5 56-09-7 2-amino-4-hydroxy-1H-pyrimidin-6-one Not in list C4H5N3O2 C1=C(N=C(NC1=O)N)O InChI=1S/C4H5N3O2/c5-4-6-2(8)1-3(9)7-4/h1H,(H4,5,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Austria Amidosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron 09Nov2008 2008 doi:10.2903/j.efsa.2008.116r
+Amidosulfuron 120923-37-7 single chemical entity Component is a metabolite of the substance 2-amino-4,6-dihydroxypyrimidine 200-256-5 56-09-7 2-amino-4-hydroxy-1H-pyrimidin-6-one Not in list C4H5N3O2 C1=C(N=C(NC1=O)N)O InChI=1S/C4H5N3O2/c5-4-6-2(8)1-3(9)7-4/h1H,(H4,5,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Austria Amidosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron 09Nov2008 2008 doi:10.2903/j.efsa.2008.116r
+Amidosulfuron 120923-37-7 single chemical entity Component is a metabolite of the substance 2-amino-4,6-dihydroxypyrimidine 200-256-5 56-09-7 2-amino-4-hydroxy-1H-pyrimidin-6-one Not in list C4H5N3O2 C1=C(N=C(NC1=O)N)O InChI=1S/C4H5N3O2/c5-4-6-2(8)1-3(9)7-4/h1H,(H4,5,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Austria Amidosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron 09Nov2008 2008 doi:10.2903/j.efsa.2008.116r
+Amidosulfuron 120923-37-7 single chemical entity Component is a metabolite of the substance 2-amino-4,6-dihydroxypyrimidine 200-256-5 56-09-7 2-amino-4-hydroxy-1H-pyrimidin-6-one Not in list C4H5N3O2 C1=C(N=C(NC1=O)N)O InChI=1S/C4H5N3O2/c5-4-6-2(8)1-3(9)7-4/h1H,(H4,5,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Austria Amidosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron 09Nov2008 2008 doi:10.2903/j.efsa.2008.116r
+Amidosulfuron 120923-37-7 single chemical entity Component is a metabolite of the substance 2-amino-4,6-dihydroxypyrimidine 200-256-5 56-09-7 2-amino-4-hydroxy-1H-pyrimidin-6-one Not in list C4H5N3O2 C1=C(N=C(NC1=O)N)O InChI=1S/C4H5N3O2/c5-4-6-2(8)1-3(9)7-4/h1H,(H4,5,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Austria Amidosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron 09Nov2008 2008 doi:10.2903/j.efsa.2008.116r
+Amidosulfuron 120923-37-7 single chemical entity Component is a metabolite of the substance 2-amino-4,6-dihydroxypyrimidine 200-256-5 56-09-7 2-amino-4-hydroxy-1H-pyrimidin-6-one Not in list C4H5N3O2 C1=C(N=C(NC1=O)N)O InChI=1S/C4H5N3O2/c5-4-6-2(8)1-3(9)7-4/h1H,(H4,5,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Austria Amidosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron 09Nov2008 2008 doi:10.2903/j.efsa.2008.116r
+Amidosulfuron 120923-37-7 single chemical entity Component is a metabolite of the substance 2-amino-4,6-dihydroxypyrimidine 200-256-5 56-09-7 2-amino-4-hydroxy-1H-pyrimidin-6-one Not in list C4H5N3O2 C1=C(N=C(NC1=O)N)O InChI=1S/C4H5N3O2/c5-4-6-2(8)1-3(9)7-4/h1H,(H4,5,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Austria Amidosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron 09Nov2008 2008 doi:10.2903/j.efsa.2008.116r
+Amidosulfuron 120923-37-7 single chemical entity Component is a metabolite of the substance 2-amino-4,6-dihydroxypyrimidine 200-256-5 56-09-7 2-amino-4-hydroxy-1H-pyrimidin-6-one Not in list C4H5N3O2 C1=C(N=C(NC1=O)N)O InChI=1S/C4H5N3O2/c5-4-6-2(8)1-3(9)7-4/h1H,(H4,5,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Austria Amidosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron 09Nov2008 2008 doi:10.2903/j.efsa.2008.116r
+Amidosulfuron 120923-37-7 single chemical entity Component is a metabolite of the substance 2-amino-4,6-dihydroxypyrimidine 200-256-5 56-09-7 2-amino-4-hydroxy-1H-pyrimidin-6-one Not in list C4H5N3O2 C1=C(N=C(NC1=O)N)O InChI=1S/C4H5N3O2/c5-4-6-2(8)1-3(9)7-4/h1H,(H4,5,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Austria Amidosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron 09Nov2008 2008 doi:10.2903/j.efsa.2008.116r
+Amidosulfuron 120923-37-7 single chemical entity Component is a metabolite of the substance 2-amino-4,6-dihydroxypyrimidine 200-256-5 56-09-7 2-amino-4-hydroxy-1H-pyrimidin-6-one Not in list C4H5N3O2 C1=C(N=C(NC1=O)N)O InChI=1S/C4H5N3O2/c5-4-6-2(8)1-3(9)7-4/h1H,(H4,5,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Austria Amidosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron 09Nov2008 2008 doi:10.2903/j.efsa.2008.116r
+Amidosulfuron 120923-37-7 single chemical entity Component is a metabolite of the substance 2-Amino-4,6-dimethoxypyrimidine 252-969-6 36315-01-2 4,6-Dimethoxypyrimidin-2-amine Not in list C6H9N3O2 COC1=CC(=NC(=N1)N)OC InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Austria Amidosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron 09Nov2008 2008 doi:10.2903/j.efsa.2008.116r
+Amidosulfuron 120923-37-7 single chemical entity Component is a metabolite of the substance 2-Amino-4,6-dimethoxypyrimidine 252-969-6 36315-01-2 4,6-Dimethoxypyrimidin-2-amine Not in list C6H9N3O2 COC1=CC(=NC(=N1)N)OC InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Austria Amidosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron 09Nov2008 2008 doi:10.2903/j.efsa.2008.116r
+Amidosulfuron 120923-37-7 single chemical entity Component is a metabolite of the substance 2-Amino-4,6-dimethoxypyrimidine 252-969-6 36315-01-2 4,6-Dimethoxypyrimidin-2-amine Not in list C6H9N3O2 COC1=CC(=NC(=N1)N)OC InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Austria Amidosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron 09Nov2008 2008 doi:10.2903/j.efsa.2008.116r
+Amidosulfuron 120923-37-7 single chemical entity Component is a metabolite of the substance 2-Amino-4,6-dimethoxypyrimidine 252-969-6 36315-01-2 4,6-Dimethoxypyrimidin-2-amine Not in list C6H9N3O2 COC1=CC(=NC(=N1)N)OC InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Austria Amidosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron 09Nov2008 2008 doi:10.2903/j.efsa.2008.116r
+Amidosulfuron 120923-37-7 single chemical entity Component is a metabolite of the substance 2-Amino-4,6-dimethoxypyrimidine 252-969-6 36315-01-2 4,6-Dimethoxypyrimidin-2-amine Not in list C6H9N3O2 COC1=CC(=NC(=N1)N)OC InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Austria Amidosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron 09Nov2008 2008 doi:10.2903/j.efsa.2008.116r
+Amidosulfuron 120923-37-7 single chemical entity Component is a metabolite of the substance 2-Amino-4,6-dimethoxypyrimidine 252-969-6 36315-01-2 4,6-Dimethoxypyrimidin-2-amine Not in list C6H9N3O2 COC1=CC(=NC(=N1)N)OC InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Austria Amidosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron 09Nov2008 2008 doi:10.2903/j.efsa.2008.116r
+Amidosulfuron 120923-37-7 single chemical entity Component is a metabolite of the substance 2-Amino-4,6-dimethoxypyrimidine 252-969-6 36315-01-2 4,6-Dimethoxypyrimidin-2-amine Not in list C6H9N3O2 COC1=CC(=NC(=N1)N)OC InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Austria Amidosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron 09Nov2008 2008 doi:10.2903/j.efsa.2008.116r
+Amidosulfuron 120923-37-7 single chemical entity Component is a metabolite of the substance 2-Amino-4,6-dimethoxypyrimidine 252-969-6 36315-01-2 4,6-Dimethoxypyrimidin-2-amine Not in list C6H9N3O2 COC1=CC(=NC(=N1)N)OC InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Austria Amidosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron 09Nov2008 2008 doi:10.2903/j.efsa.2008.116r
+Amidosulfuron 120923-37-7 single chemical entity Component is a metabolite of the substance 2-Amino-4,6-dimethoxypyrimidine 252-969-6 36315-01-2 4,6-Dimethoxypyrimidin-2-amine Not in list C6H9N3O2 COC1=CC(=NC(=N1)N)OC InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Austria Amidosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron 09Nov2008 2008 doi:10.2903/j.efsa.2008.116r
+Amidosulfuron 120923-37-7 single chemical entity Component is a metabolite of the substance 2-Amino-4,6-dimethoxypyrimidine 252-969-6 36315-01-2 4,6-Dimethoxypyrimidin-2-amine Not in list C6H9N3O2 COC1=CC(=NC(=N1)N)OC InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Austria Amidosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron 09Nov2008 2008 doi:10.2903/j.efsa.2008.116r
+Amidosulfuron 120923-37-7 single chemical entity Component is a metabolite of the substance 2-Amino-4,6-dimethoxypyrimidine 252-969-6 36315-01-2 4,6-Dimethoxypyrimidin-2-amine Not in list C6H9N3O2 COC1=CC(=NC(=N1)N)OC InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Austria Amidosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron 09Nov2008 2008 doi:10.2903/j.efsa.2008.116r
+Amidosulfuron 120923-37-7 single chemical entity Component is a metabolite of the substance 2-Amino-4,6-dimethoxypyrimidine 252-969-6 36315-01-2 4,6-Dimethoxypyrimidin-2-amine Not in list C6H9N3O2 COC1=CC(=NC(=N1)N)OC InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Austria Amidosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron 09Nov2008 2008 doi:10.2903/j.efsa.2008.116r
+Carbetamide 240-286-6 16118-49-3 single chemical entity Component is identical to the substance Carbetamide 240-286-6 16118-49-3 1-(ethylamino)-1-oxopropan-2-yl phenylcarbamate Carbetamide C12H16N2O3 O=C(NCC)C(OC(NC1=CC=CC=C1)=O)C InChI=1S/C12H16N2O3/c1-3-13-11(15)9(2)17-12(16)14-10-7-5-4-6-8-10/h4-9H,3H2,1-2H3,(H,13,15)(H,14,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Carbetamide (Revised DAR of December 2005) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1913
+Carbetamide 240-286-6 16118-49-3 single chemical entity Component is identical to the substance Carbetamide 240-286-6 16118-49-3 1-(ethylamino)-1-oxopropan-2-yl phenylcarbamate Carbetamide C12H16N2O3 O=C(NCC)C(OC(NC1=CC=CC=C1)=O)C InChI=1S/C12H16N2O3/c1-3-13-11(15)9(2)17-12(16)14-10-7-5-4-6-8-10/h4-9H,3H2,1-2H3,(H,13,15)(H,14,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Carbetamide (Revised DAR of December 2005) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1913
+Carbetamide 240-286-6 16118-49-3 single chemical entity Component is identical to the substance Carbetamide 240-286-6 16118-49-3 1-(ethylamino)-1-oxopropan-2-yl phenylcarbamate Carbetamide C12H16N2O3 O=C(NCC)C(OC(NC1=CC=CC=C1)=O)C InChI=1S/C12H16N2O3/c1-3-13-11(15)9(2)17-12(16)14-10-7-5-4-6-8-10/h4-9H,3H2,1-2H3,(H,13,15)(H,14,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: France Carbetamide (Revised DAR of December 2005) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1913
+Carbetamide 240-286-6 16118-49-3 single chemical entity Component is identical to the substance Carbetamide 240-286-6 16118-49-3 1-(ethylamino)-1-oxopropan-2-yl phenylcarbamate Carbetamide C12H16N2O3 O=C(NCC)C(OC(NC1=CC=CC=C1)=O)C InChI=1S/C12H16N2O3/c1-3-13-11(15)9(2)17-12(16)14-10-7-5-4-6-8-10/h4-9H,3H2,1-2H3,(H,13,15)(H,14,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Carbetamide (Revised DAR of December 2005) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1913
+Carbetamide 240-286-6 16118-49-3 single chemical entity Component is identical to the substance Carbetamide 240-286-6 16118-49-3 1-(ethylamino)-1-oxopropan-2-yl phenylcarbamate Carbetamide C12H16N2O3 O=C(NCC)C(OC(NC1=CC=CC=C1)=O)C InChI=1S/C12H16N2O3/c1-3-13-11(15)9(2)17-12(16)14-10-7-5-4-6-8-10/h4-9H,3H2,1-2H3,(H,13,15)(H,14,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Carbetamide (Revised DAR of December 2005) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1913
+Carbetamide 240-286-6 16118-49-3 single chemical entity Component is identical to the substance Carbetamide 240-286-6 16118-49-3 1-(ethylamino)-1-oxopropan-2-yl phenylcarbamate Carbetamide C12H16N2O3 O=C(NCC)C(OC(NC1=CC=CC=C1)=O)C InChI=1S/C12H16N2O3/c1-3-13-11(15)9(2)17-12(16)14-10-7-5-4-6-8-10/h4-9H,3H2,1-2H3,(H,13,15)(H,14,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Carbetamide (Revised DAR of December 2005) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1913
+Carbetamide 240-286-6 16118-49-3 single chemical entity Component is identical to the substance Carbetamide 240-286-6 16118-49-3 1-(ethylamino)-1-oxopropan-2-yl phenylcarbamate Carbetamide C12H16N2O3 O=C(NCC)C(OC(NC1=CC=CC=C1)=O)C InChI=1S/C12H16N2O3/c1-3-13-11(15)9(2)17-12(16)14-10-7-5-4-6-8-10/h4-9H,3H2,1-2H3,(H,13,15)(H,14,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: France Carbetamide (Revised DAR of December 2005) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1913
+Carbetamide 240-286-6 16118-49-3 single chemical entity Component is identical to the substance Carbetamide 240-286-6 16118-49-3 1-(ethylamino)-1-oxopropan-2-yl phenylcarbamate Carbetamide C12H16N2O3 O=C(NCC)C(OC(NC1=CC=CC=C1)=O)C InChI=1S/C12H16N2O3/c1-3-13-11(15)9(2)17-12(16)14-10-7-5-4-6-8-10/h4-9H,3H2,1-2H3,(H,13,15)(H,14,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Carbetamide (Revised DAR of December 2005) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1913
+Carbetamide 240-286-6 16118-49-3 single chemical entity Component is identical to the substance Carbetamide 240-286-6 16118-49-3 1-(ethylamino)-1-oxopropan-2-yl phenylcarbamate Carbetamide C12H16N2O3 O=C(NCC)C(OC(NC1=CC=CC=C1)=O)C InChI=1S/C12H16N2O3/c1-3-13-11(15)9(2)17-12(16)14-10-7-5-4-6-8-10/h4-9H,3H2,1-2H3,(H,13,15)(H,14,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Carbetamide (Revised DAR of December 2005) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1913
+Carbetamide 240-286-6 16118-49-3 single chemical entity Component is identical to the substance Carbetamide 240-286-6 16118-49-3 1-(ethylamino)-1-oxopropan-2-yl phenylcarbamate Carbetamide C12H16N2O3 O=C(NCC)C(OC(NC1=CC=CC=C1)=O)C InChI=1S/C12H16N2O3/c1-3-13-11(15)9(2)17-12(16)14-10-7-5-4-6-8-10/h4-9H,3H2,1-2H3,(H,13,15)(H,14,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Carbetamide (Revised DAR of December 2005) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1913
+Carbetamide 240-286-6 16118-49-3 single chemical entity Component is identical to the substance Carbetamide 240-286-6 16118-49-3 1-(ethylamino)-1-oxopropan-2-yl phenylcarbamate Carbetamide C12H16N2O3 O=C(NCC)C(OC(NC1=CC=CC=C1)=O)C InChI=1S/C12H16N2O3/c1-3-13-11(15)9(2)17-12(16)14-10-7-5-4-6-8-10/h4-9H,3H2,1-2H3,(H,13,15)(H,14,16) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: France Carbetamide (Revised DAR of December 2005) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1913
+Carbetamide 240-286-6 16118-49-3 single chemical entity Component is identical to the substance Carbetamide 240-286-6 16118-49-3 1-(ethylamino)-1-oxopropan-2-yl phenylcarbamate Carbetamide C12H16N2O3 O=C(NCC)C(OC(NC1=CC=CC=C1)=O)C InChI=1S/C12H16N2O3/c1-3-13-11(15)9(2)17-12(16)14-10-7-5-4-6-8-10/h4-9H,3H2,1-2H3,(H,13,15)(H,14,16) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: France Carbetamide (Revised DAR of December 2005) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1913
+Carbetamide 240-286-6 16118-49-3 single chemical entity Component is identical to the substance Carbetamide 240-286-6 16118-49-3 1-(ethylamino)-1-oxopropan-2-yl phenylcarbamate Carbetamide C12H16N2O3 O=C(NCC)C(OC(NC1=CC=CC=C1)=O)C InChI=1S/C12H16N2O3/c1-3-13-11(15)9(2)17-12(16)14-10-7-5-4-6-8-10/h4-9H,3H2,1-2H3,(H,13,15)(H,14,16) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: France Carbetamide (Revised DAR of December 2005) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1913
+Carbetamide 240-286-6 16118-49-3 single chemical entity Component is identical to the substance Carbetamide 240-286-6 16118-49-3 1-(ethylamino)-1-oxopropan-2-yl phenylcarbamate Carbetamide C12H16N2O3 O=C(NCC)C(OC(NC1=CC=CC=C1)=O)C InChI=1S/C12H16N2O3/c1-3-13-11(15)9(2)17-12(16)14-10-7-5-4-6-8-10/h4-9H,3H2,1-2H3,(H,13,15)(H,14,16) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: France Carbetamide (Revised DAR of December 2005) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1913
+Carbetamide 240-286-6 16118-49-3 single chemical entity Component is identical to the substance Carbetamide 240-286-6 16118-49-3 1-(ethylamino)-1-oxopropan-2-yl phenylcarbamate Carbetamide C12H16N2O3 O=C(NCC)C(OC(NC1=CC=CC=C1)=O)C InChI=1S/C12H16N2O3/c1-3-13-11(15)9(2)17-12(16)14-10-7-5-4-6-8-10/h4-9H,3H2,1-2H3,(H,13,15)(H,14,16) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 20 Male/Female oral: gavage 30.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: France Carbetamide (Revised DAR of December 2005) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1913
+Carbetamide 240-286-6 16118-49-3 single chemical entity Component is identical to the substance Carbetamide 240-286-6 16118-49-3 1-(ethylamino)-1-oxopropan-2-yl phenylcarbamate Carbetamide C12H16N2O3 O=C(NCC)C(OC(NC1=CC=CC=C1)=O)C InChI=1S/C12H16N2O3/c1-3-13-11(15)9(2)17-12(16)14-10-7-5-4-6-8-10/h4-9H,3H2,1-2H3,(H,13,15)(H,14,16) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 20 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: France Carbetamide (Revised DAR of December 2005) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1913
+Carbetamide 240-286-6 16118-49-3 single chemical entity Component is identical to the substance Carbetamide 240-286-6 16118-49-3 1-(ethylamino)-1-oxopropan-2-yl phenylcarbamate Carbetamide C12H16N2O3 O=C(NCC)C(OC(NC1=CC=CC=C1)=O)C InChI=1S/C12H16N2O3/c1-3-13-11(15)9(2)17-12(16)14-10-7-5-4-6-8-10/h4-9H,3H2,1-2H3,(H,13,15)(H,14,16) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity RMS: France Carbetamide (Revised DAR of December 2005) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1913
+Carbetamide 240-286-6 16118-49-3 single chemical entity Component is identical to the substance Carbetamide 240-286-6 16118-49-3 1-(ethylamino)-1-oxopropan-2-yl phenylcarbamate Carbetamide C12H16N2O3 O=C(NCC)C(OC(NC1=CC=CC=C1)=O)C InChI=1S/C12H16N2O3/c1-3-13-11(15)9(2)17-12(16)14-10-7-5-4-6-8-10/h4-9H,3H2,1-2H3,(H,13,15)(H,14,16) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity RMS: France Carbetamide (Revised DAR of December 2005) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1913
+Carbetamide 240-286-6 16118-49-3 single chemical entity Component is identical to the substance Carbetamide 240-286-6 16118-49-3 1-(ethylamino)-1-oxopropan-2-yl phenylcarbamate Carbetamide C12H16N2O3 O=C(NCC)C(OC(NC1=CC=CC=C1)=O)C InChI=1S/C12H16N2O3/c1-3-13-11(15)9(2)17-12(16)14-10-7-5-4-6-8-10/h4-9H,3H2,1-2H3,(H,13,15)(H,14,16) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 5 Female oral: gavage 3.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: France Carbetamide (Revised DAR of December 2005) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1913
+Carbetamide 240-286-6 16118-49-3 single chemical entity Component is identical to the substance Carbetamide 240-286-6 16118-49-3 1-(ethylamino)-1-oxopropan-2-yl phenylcarbamate Carbetamide C12H16N2O3 O=C(NCC)C(OC(NC1=CC=CC=C1)=O)C InChI=1S/C12H16N2O3/c1-3-13-11(15)9(2)17-12(16)14-10-7-5-4-6-8-10/h4-9H,3H2,1-2H3,(H,13,15)(H,14,16) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 5 Female oral: gavage 2.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: France Carbetamide (Revised DAR of December 2005) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1913
+Carbetamide 240-286-6 16118-49-3 single chemical entity Component is identical to the substance Carbetamide 240-286-6 16118-49-3 1-(ethylamino)-1-oxopropan-2-yl phenylcarbamate Carbetamide C12H16N2O3 O=C(NCC)C(OC(NC1=CC=CC=C1)=O)C InChI=1S/C12H16N2O3/c1-3-13-11(15)9(2)17-12(16)14-10-7-5-4-6-8-10/h4-9H,3H2,1-2H3,(H,13,15)(H,14,16) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 5 Female oral: gavage 8.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: France Carbetamide (Revised DAR of December 2005) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1913
+Carbetamide 240-286-6 16118-49-3 single chemical entity Component is identical to the substance Carbetamide 240-286-6 16118-49-3 1-(ethylamino)-1-oxopropan-2-yl phenylcarbamate Carbetamide C12H16N2O3 O=C(NCC)C(OC(NC1=CC=CC=C1)=O)C InChI=1S/C12H16N2O3/c1-3-13-11(15)9(2)17-12(16)14-10-7-5-4-6-8-10/h4-9H,3H2,1-2H3,(H,13,15)(H,14,16) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 5 Female oral: gavage 0.2500000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: France Carbetamide (Revised DAR of December 2005) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1913
+Carbetamide 240-286-6 16118-49-3 single chemical entity Component is identical to the substance Carbetamide 240-286-6 16118-49-3 1-(ethylamino)-1-oxopropan-2-yl phenylcarbamate Carbetamide C12H16N2O3 O=C(NCC)C(OC(NC1=CC=CC=C1)=O)C InChI=1S/C12H16N2O3/c1-3-13-11(15)9(2)17-12(16)14-10-7-5-4-6-8-10/h4-9H,3H2,1-2H3,(H,13,15)(H,14,16) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 5 Female oral: gavage 4.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: France Carbetamide (Revised DAR of December 2005) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1913
+Carbetamide 240-286-6 16118-49-3 single chemical entity Component is identical to the substance Carbetamide 240-286-6 16118-49-3 1-(ethylamino)-1-oxopropan-2-yl phenylcarbamate Carbetamide C12H16N2O3 O=C(NCC)C(OC(NC1=CC=CC=C1)=O)C InChI=1S/C12H16N2O3/c1-3-13-11(15)9(2)17-12(16)14-10-7-5-4-6-8-10/h4-9H,3H2,1-2H3,(H,13,15)(H,14,16) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 5 Female oral: gavage 1.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: France Carbetamide (Revised DAR of December 2005) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1913
+Carbetamide 240-286-6 16118-49-3 single chemical entity Component is identical to the substance Carbetamide 240-286-6 16118-49-3 1-(ethylamino)-1-oxopropan-2-yl phenylcarbamate Carbetamide C12H16N2O3 O=C(NCC)C(OC(NC1=CC=CC=C1)=O)C InChI=1S/C12H16N2O3/c1-3-13-11(15)9(2)17-12(16)14-10-7-5-4-6-8-10/h4-9H,3H2,1-2H3,(H,13,15)(H,14,16) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 5 Female oral: gavage 1.5000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: France Carbetamide (Revised DAR of December 2005) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1913
+Carbetamide 240-286-6 16118-49-3 single chemical entity Component is identical to the substance Carbetamide 240-286-6 16118-49-3 1-(ethylamino)-1-oxopropan-2-yl phenylcarbamate Carbetamide C12H16N2O3 O=C(NCC)C(OC(NC1=CC=CC=C1)=O)C InChI=1S/C12H16N2O3/c1-3-13-11(15)9(2)17-12(16)14-10-7-5-4-6-8-10/h4-9H,3H2,1-2H3,(H,13,15)(H,14,16) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 5 Female oral: gavage 0.5000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: France Carbetamide (Revised DAR of December 2005) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1913
+Carbetamide 240-286-6 16118-49-3 single chemical entity Component is identical to the substance Carbetamide 240-286-6 16118-49-3 1-(ethylamino)-1-oxopropan-2-yl phenylcarbamate Carbetamide C12H16N2O3 O=C(NCC)C(OC(NC1=CC=CC=C1)=O)C InChI=1S/C12H16N2O3/c1-3-13-11(15)9(2)17-12(16)14-10-7-5-4-6-8-10/h4-9H,3H2,1-2H3,(H,13,15)(H,14,16) organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Crj:CD(SD) 6 Male oral: gavage 16.0000000000 h yes, concurrent vehicle not applicable Negative RMS: France Carbetamide (Revised DAR of December 2005) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1913
+Carbetamide 240-286-6 16118-49-3 single chemical entity Component is identical to the substance Carbetamide 240-286-6 16118-49-3 1-(ethylamino)-1-oxopropan-2-yl phenylcarbamate Carbetamide C12H16N2O3 O=C(NCC)C(OC(NC1=CC=CC=C1)=O)C InChI=1S/C12H16N2O3/c1-3-13-11(15)9(2)17-12(16)14-10-7-5-4-6-8-10/h4-9H,3H2,1-2H3,(H,13,15)(H,14,16) organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Crj:CD(SD) 6 Male oral: gavage 2.0000000000 h yes, concurrent vehicle not applicable Negative RMS: France Carbetamide (Revised DAR of December 2005) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1913
+Amisulbrom 348635-87-0 single chemical entity Component is identical to the substance Amisulbrom 348635-87-0 3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1,2,4-triazole-1-sulfonamide Amisulbrom C13H13BrFN5O4S2 CC1=C(C2=C(N1S(=O)(=O)C3=NN(C=N3)S(=O)(=O)N(C)C)C=C(C=C2)F)Br InChI=1S/C13H13BrFN5O4S2/c1-8-12(14)10-5-4-9(15)6-11(10)20(8)25(21,22)13-16-7-19(17-13)26(23,24)18(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The United Kingdom Amisulbrom 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom 07Apr2014 2014 doi:10.2903/j.efsa.2014.3237
+Amisulbrom 348635-87-0 single chemical entity Component is identical to the substance Amisulbrom 348635-87-0 3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1,2,4-triazole-1-sulfonamide Amisulbrom C13H13BrFN5O4S2 CC1=C(C2=C(N1S(=O)(=O)C3=NN(C=N3)S(=O)(=O)N(C)C)C=C(C=C2)F)Br InChI=1S/C13H13BrFN5O4S2/c1-8-12(14)10-5-4-9(15)6-11(10)20(8)25(21,22)13-16-7-19(17-13)26(23,24)18(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The United Kingdom Amisulbrom 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom 07Apr2014 2014 doi:10.2903/j.efsa.2014.3237
+Amisulbrom 348635-87-0 single chemical entity Component is identical to the substance Amisulbrom 348635-87-0 3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1,2,4-triazole-1-sulfonamide Amisulbrom C13H13BrFN5O4S2 CC1=C(C2=C(N1S(=O)(=O)C3=NN(C=N3)S(=O)(=O)N(C)C)C=C(C=C2)F)Br InChI=1S/C13H13BrFN5O4S2/c1-8-12(14)10-5-4-9(15)6-11(10)20(8)25(21,22)13-16-7-19(17-13)26(23,24)18(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: The United Kingdom Amisulbrom 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom 07Apr2014 2014 doi:10.2903/j.efsa.2014.3237
+Amisulbrom 348635-87-0 single chemical entity Component is identical to the substance Amisulbrom 348635-87-0 3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1,2,4-triazole-1-sulfonamide Amisulbrom C13H13BrFN5O4S2 CC1=C(C2=C(N1S(=O)(=O)C3=NN(C=N3)S(=O)(=O)N(C)C)C=C(C=C2)F)Br InChI=1S/C13H13BrFN5O4S2/c1-8-12(14)10-5-4-9(15)6-11(10)20(8)25(21,22)13-16-7-19(17-13)26(23,24)18(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The United Kingdom Amisulbrom 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom 07Apr2014 2014 doi:10.2903/j.efsa.2014.3237
+Amisulbrom 348635-87-0 single chemical entity Component is identical to the substance Amisulbrom 348635-87-0 3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1,2,4-triazole-1-sulfonamide Amisulbrom C13H13BrFN5O4S2 CC1=C(C2=C(N1S(=O)(=O)C3=NN(C=N3)S(=O)(=O)N(C)C)C=C(C=C2)F)Br InChI=1S/C13H13BrFN5O4S2/c1-8-12(14)10-5-4-9(15)6-11(10)20(8)25(21,22)13-16-7-19(17-13)26(23,24)18(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The United Kingdom Amisulbrom 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom 07Apr2014 2014 doi:10.2903/j.efsa.2014.3237
+Amisulbrom 348635-87-0 single chemical entity Component is identical to the substance Amisulbrom 348635-87-0 3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1,2,4-triazole-1-sulfonamide Amisulbrom C13H13BrFN5O4S2 CC1=C(C2=C(N1S(=O)(=O)C3=NN(C=N3)S(=O)(=O)N(C)C)C=C(C=C2)F)Br InChI=1S/C13H13BrFN5O4S2/c1-8-12(14)10-5-4-9(15)6-11(10)20(8)25(21,22)13-16-7-19(17-13)26(23,24)18(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The United Kingdom Amisulbrom 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom 07Apr2014 2014 doi:10.2903/j.efsa.2014.3237
+Amisulbrom 348635-87-0 single chemical entity Component is identical to the substance Amisulbrom 348635-87-0 3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1,2,4-triazole-1-sulfonamide Amisulbrom C13H13BrFN5O4S2 CC1=C(C2=C(N1S(=O)(=O)C3=NN(C=N3)S(=O)(=O)N(C)C)C=C(C=C2)F)Br InChI=1S/C13H13BrFN5O4S2/c1-8-12(14)10-5-4-9(15)6-11(10)20(8)25(21,22)13-16-7-19(17-13)26(23,24)18(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: The United Kingdom Amisulbrom 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom 07Apr2014 2014 doi:10.2903/j.efsa.2014.3237
+Amisulbrom 348635-87-0 single chemical entity Component is identical to the substance Amisulbrom 348635-87-0 3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1,2,4-triazole-1-sulfonamide Amisulbrom C13H13BrFN5O4S2 CC1=C(C2=C(N1S(=O)(=O)C3=NN(C=N3)S(=O)(=O)N(C)C)C=C(C=C2)F)Br InChI=1S/C13H13BrFN5O4S2/c1-8-12(14)10-5-4-9(15)6-11(10)20(8)25(21,22)13-16-7-19(17-13)26(23,24)18(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The United Kingdom Amisulbrom 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom 07Apr2014 2014 doi:10.2903/j.efsa.2014.3237
+Amisulbrom 348635-87-0 single chemical entity Component is identical to the substance Amisulbrom 348635-87-0 3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1,2,4-triazole-1-sulfonamide Amisulbrom C13H13BrFN5O4S2 CC1=C(C2=C(N1S(=O)(=O)C3=NN(C=N3)S(=O)(=O)N(C)C)C=C(C=C2)F)Br InChI=1S/C13H13BrFN5O4S2/c1-8-12(14)10-5-4-9(15)6-11(10)20(8)25(21,22)13-16-7-19(17-13)26(23,24)18(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The United Kingdom Amisulbrom 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom 07Apr2014 2014 doi:10.2903/j.efsa.2014.3237
+Amisulbrom 348635-87-0 single chemical entity Component is identical to the substance Amisulbrom 348635-87-0 3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1,2,4-triazole-1-sulfonamide Amisulbrom C13H13BrFN5O4S2 CC1=C(C2=C(N1S(=O)(=O)C3=NN(C=N3)S(=O)(=O)N(C)C)C=C(C=C2)F)Br InChI=1S/C13H13BrFN5O4S2/c1-8-12(14)10-5-4-9(15)6-11(10)20(8)25(21,22)13-16-7-19(17-13)26(23,24)18(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The United Kingdom Amisulbrom 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom 07Apr2014 2014 doi:10.2903/j.efsa.2014.3237
+Amisulbrom 348635-87-0 single chemical entity Component is a metabolite of the substance 3-bromo-6-fluoro-2-methyl-1-(1H-1,2,4-triazol-3-ylsulfonyl)-1H-indole 3-bromo-6-fluoro-2-methyl-1-(1H-1,2,4-triazol-3-ylsulfonyl)-1H-indole Not in list C11H8BrFN4O2S O=S(=O)(n2c1cc(F)ccc1c(Br)c2C)c3ncnn3 InChI=1/C11H8BrFN4O2S/c1-6-10(12)8-3-2-7(13)4-9(8)17(6)20(18,19)11-14-5-15-16-11/h2-5H,1H3,(H,14,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The United Kingdom Amisulbrom 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom 07Apr2014 2014 doi:10.2903/j.efsa.2014.3237
+Amisulbrom 348635-87-0 single chemical entity Component is a metabolite of the substance 3-bromo-6-fluoro-2-methyl-1-(1H-1,2,4-triazol-3-ylsulfonyl)-1H-indole 3-bromo-6-fluoro-2-methyl-1-(1H-1,2,4-triazol-3-ylsulfonyl)-1H-indole Not in list C11H8BrFN4O2S O=S(=O)(n2c1cc(F)ccc1c(Br)c2C)c3ncnn3 InChI=1/C11H8BrFN4O2S/c1-6-10(12)8-3-2-7(13)4-9(8)17(6)20(18,19)11-14-5-15-16-11/h2-5H,1H3,(H,14,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The United Kingdom Amisulbrom 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom 07Apr2014 2014 doi:10.2903/j.efsa.2014.3237
+Amisulbrom 348635-87-0 single chemical entity Component is a metabolite of the substance 3-bromo-6-fluoro-2-methyl-1-(1H-1,2,4-triazol-3-ylsulfonyl)-1H-indole 3-bromo-6-fluoro-2-methyl-1-(1H-1,2,4-triazol-3-ylsulfonyl)-1H-indole Not in list C11H8BrFN4O2S O=S(=O)(n2c1cc(F)ccc1c(Br)c2C)c3ncnn3 InChI=1/C11H8BrFN4O2S/c1-6-10(12)8-3-2-7(13)4-9(8)17(6)20(18,19)11-14-5-15-16-11/h2-5H,1H3,(H,14,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: The United Kingdom Amisulbrom 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom 07Apr2014 2014 doi:10.2903/j.efsa.2014.3237
+Amisulbrom 348635-87-0 single chemical entity Component is a metabolite of the substance 3-bromo-6-fluoro-2-methyl-1-(1H-1,2,4-triazol-3-ylsulfonyl)-1H-indole 3-bromo-6-fluoro-2-methyl-1-(1H-1,2,4-triazol-3-ylsulfonyl)-1H-indole Not in list C11H8BrFN4O2S O=S(=O)(n2c1cc(F)ccc1c(Br)c2C)c3ncnn3 InChI=1/C11H8BrFN4O2S/c1-6-10(12)8-3-2-7(13)4-9(8)17(6)20(18,19)11-14-5-15-16-11/h2-5H,1H3,(H,14,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The United Kingdom Amisulbrom 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom 07Apr2014 2014 doi:10.2903/j.efsa.2014.3237
+Amisulbrom 348635-87-0 single chemical entity Component is a metabolite of the substance 3-bromo-6-fluoro-2-methyl-1-(1H-1,2,4-triazol-3-ylsulfonyl)-1H-indole 3-bromo-6-fluoro-2-methyl-1-(1H-1,2,4-triazol-3-ylsulfonyl)-1H-indole Not in list C11H8BrFN4O2S O=S(=O)(n2c1cc(F)ccc1c(Br)c2C)c3ncnn3 InChI=1/C11H8BrFN4O2S/c1-6-10(12)8-3-2-7(13)4-9(8)17(6)20(18,19)11-14-5-15-16-11/h2-5H,1H3,(H,14,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: The United Kingdom Amisulbrom 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom 07Apr2014 2014 doi:10.2903/j.efsa.2014.3237
+Amisulbrom 348635-87-0 single chemical entity Component is a metabolite of the substance 3-bromo-6-fluoro-2-methyl-1-(1H-1,2,4-triazol-3-ylsulfonyl)-1H-indole 3-bromo-6-fluoro-2-methyl-1-(1H-1,2,4-triazol-3-ylsulfonyl)-1H-indole Not in list C11H8BrFN4O2S O=S(=O)(n2c1cc(F)ccc1c(Br)c2C)c3ncnn3 InChI=1/C11H8BrFN4O2S/c1-6-10(12)8-3-2-7(13)4-9(8)17(6)20(18,19)11-14-5-15-16-11/h2-5H,1H3,(H,14,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The United Kingdom Amisulbrom 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom 07Apr2014 2014 doi:10.2903/j.efsa.2014.3237
+Amisulbrom 348635-87-0 single chemical entity Component is a metabolite of the substance 3-bromo-6-fluoro-2-methyl-1-(1H-1,2,4-triazol-3-ylsulfonyl)-1H-indole 3-bromo-6-fluoro-2-methyl-1-(1H-1,2,4-triazol-3-ylsulfonyl)-1H-indole Not in list C11H8BrFN4O2S O=S(=O)(n2c1cc(F)ccc1c(Br)c2C)c3ncnn3 InChI=1/C11H8BrFN4O2S/c1-6-10(12)8-3-2-7(13)4-9(8)17(6)20(18,19)11-14-5-15-16-11/h2-5H,1H3,(H,14,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The United Kingdom Amisulbrom 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom 07Apr2014 2014 doi:10.2903/j.efsa.2014.3237
+Amisulbrom 348635-87-0 single chemical entity Component is a metabolite of the substance 3-bromo-6-fluoro-2-methyl-1-(1H-1,2,4-triazol-3-ylsulfonyl)-1H-indole 3-bromo-6-fluoro-2-methyl-1-(1H-1,2,4-triazol-3-ylsulfonyl)-1H-indole Not in list C11H8BrFN4O2S O=S(=O)(n2c1cc(F)ccc1c(Br)c2C)c3ncnn3 InChI=1/C11H8BrFN4O2S/c1-6-10(12)8-3-2-7(13)4-9(8)17(6)20(18,19)11-14-5-15-16-11/h2-5H,1H3,(H,14,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The United Kingdom Amisulbrom 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom 07Apr2014 2014 doi:10.2903/j.efsa.2014.3237
+Amisulbrom 348635-87-0 single chemical entity Component is a metabolite of the substance 3-bromo-6-fluoro-2-methyl-1-(1H-1,2,4-triazol-3-ylsulfonyl)-1H-indole 3-bromo-6-fluoro-2-methyl-1-(1H-1,2,4-triazol-3-ylsulfonyl)-1H-indole Not in list C11H8BrFN4O2S O=S(=O)(n2c1cc(F)ccc1c(Br)c2C)c3ncnn3 InChI=1/C11H8BrFN4O2S/c1-6-10(12)8-3-2-7(13)4-9(8)17(6)20(18,19)11-14-5-15-16-11/h2-5H,1H3,(H,14,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The United Kingdom Amisulbrom 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom 07Apr2014 2014 doi:10.2903/j.efsa.2014.3237
+Amisulbrom 348635-87-0 single chemical entity Component is a metabolite of the substance 3-bromo-6-fluoro-2-methyl-1-(1H-1,2,4-triazol-3-ylsulfonyl)-1H-indole 3-bromo-6-fluoro-2-methyl-1-(1H-1,2,4-triazol-3-ylsulfonyl)-1H-indole Not in list C11H8BrFN4O2S O=S(=O)(n2c1cc(F)ccc1c(Br)c2C)c3ncnn3 InChI=1/C11H8BrFN4O2S/c1-6-10(12)8-3-2-7(13)4-9(8)17(6)20(18,19)11-14-5-15-16-11/h2-5H,1H3,(H,14,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The United Kingdom Amisulbrom 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom 07Apr2014 2014 doi:10.2903/j.efsa.2014.3237
+Azoxystrobin 131860-33-8 single chemical entity Component is identical to the substance Azoxystrobin 131860-33-8 methyl (2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyacrylate Azoxystrobin C22H17N3O5 N#CC1=CC=CC=C1OC2=NC=NC(OC3=CC=CC=C3/C(C(OC)=O)=C\OC)=C2 InChI=1S/C22H17N3O5/c1-27-13-17(22(26)28-2)16-8-4-6-10-19(16)30-21-11-20(24-14-25-21)29-18-9-5-3-7-15(18)12-23/h3-11,13-14H,1-2H3/b17-13+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Azoxystrobin 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin 15Apr2010 2010 doi:10.2903/j.efsa.2010.1542
+Azoxystrobin 131860-33-8 single chemical entity Component is identical to the substance Azoxystrobin 131860-33-8 methyl (2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyacrylate Azoxystrobin C22H17N3O5 N#CC1=CC=CC=C1OC2=NC=NC(OC3=CC=CC=C3/C(C(OC)=O)=C\OC)=C2 InChI=1S/C22H17N3O5/c1-27-13-17(22(26)28-2)16-8-4-6-10-19(16)30-21-11-20(24-14-25-21)29-18-9-5-3-7-15(18)12-23/h3-11,13-14H,1-2H3/b17-13+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Azoxystrobin 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin 15Apr2010 2010 doi:10.2903/j.efsa.2010.1542
+Azoxystrobin 131860-33-8 single chemical entity Component is identical to the substance Azoxystrobin 131860-33-8 methyl (2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyacrylate Azoxystrobin C22H17N3O5 N#CC1=CC=CC=C1OC2=NC=NC(OC3=CC=CC=C3/C(C(OC)=O)=C\OC)=C2 InChI=1S/C22H17N3O5/c1-27-13-17(22(26)28-2)16-8-4-6-10-19(16)30-21-11-20(24-14-25-21)29-18-9-5-3-7-15(18)12-23/h3-11,13-14H,1-2H3/b17-13+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Azoxystrobin 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin 15Apr2010 2010 doi:10.2903/j.efsa.2010.1542
+Azoxystrobin 131860-33-8 single chemical entity Component is identical to the substance Azoxystrobin 131860-33-8 methyl (2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyacrylate Azoxystrobin C22H17N3O5 N#CC1=CC=CC=C1OC2=NC=NC(OC3=CC=CC=C3/C(C(OC)=O)=C\OC)=C2 InChI=1S/C22H17N3O5/c1-27-13-17(22(26)28-2)16-8-4-6-10-19(16)30-21-11-20(24-14-25-21)29-18-9-5-3-7-15(18)12-23/h3-11,13-14H,1-2H3/b17-13+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Azoxystrobin 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin 15Apr2010 2010 doi:10.2903/j.efsa.2010.1542
+Azoxystrobin 131860-33-8 single chemical entity Component is identical to the substance Azoxystrobin 131860-33-8 methyl (2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyacrylate Azoxystrobin C22H17N3O5 N#CC1=CC=CC=C1OC2=NC=NC(OC3=CC=CC=C3/C(C(OC)=O)=C\OC)=C2 InChI=1S/C22H17N3O5/c1-27-13-17(22(26)28-2)16-8-4-6-10-19(16)30-21-11-20(24-14-25-21)29-18-9-5-3-7-15(18)12-23/h3-11,13-14H,1-2H3/b17-13+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Azoxystrobin 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin 15Apr2010 2010 doi:10.2903/j.efsa.2010.1542
+Azoxystrobin 131860-33-8 single chemical entity Component is identical to the substance Azoxystrobin 131860-33-8 methyl (2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyacrylate Azoxystrobin C22H17N3O5 N#CC1=CC=CC=C1OC2=NC=NC(OC3=CC=CC=C3/C(C(OC)=O)=C\OC)=C2 InChI=1S/C22H17N3O5/c1-27-13-17(22(26)28-2)16-8-4-6-10-19(16)30-21-11-20(24-14-25-21)29-18-9-5-3-7-15(18)12-23/h3-11,13-14H,1-2H3/b17-13+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Azoxystrobin 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin 15Apr2010 2010 doi:10.2903/j.efsa.2010.1542
+Azoxystrobin 131860-33-8 single chemical entity Component is identical to the substance Azoxystrobin 131860-33-8 methyl (2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyacrylate Azoxystrobin C22H17N3O5 N#CC1=CC=CC=C1OC2=NC=NC(OC3=CC=CC=C3/C(C(OC)=O)=C\OC)=C2 InChI=1S/C22H17N3O5/c1-27-13-17(22(26)28-2)16-8-4-6-10-19(16)30-21-11-20(24-14-25-21)29-18-9-5-3-7-15(18)12-23/h3-11,13-14H,1-2H3/b17-13+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Azoxystrobin 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin 15Apr2010 2010 doi:10.2903/j.efsa.2010.1542
+Azoxystrobin 131860-33-8 single chemical entity Component is identical to the substance Azoxystrobin 131860-33-8 methyl (2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyacrylate Azoxystrobin C22H17N3O5 N#CC1=CC=CC=C1OC2=NC=NC(OC3=CC=CC=C3/C(C(OC)=O)=C\OC)=C2 InChI=1S/C22H17N3O5/c1-27-13-17(22(26)28-2)16-8-4-6-10-19(16)30-21-11-20(24-14-25-21)29-18-9-5-3-7-15(18)12-23/h3-11,13-14H,1-2H3/b17-13+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Azoxystrobin 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin 15Apr2010 2010 doi:10.2903/j.efsa.2010.1542
+Azoxystrobin 131860-33-8 single chemical entity Component is identical to the substance Azoxystrobin 131860-33-8 methyl (2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyacrylate Azoxystrobin C22H17N3O5 N#CC1=CC=CC=C1OC2=NC=NC(OC3=CC=CC=C3/C(C(OC)=O)=C\OC)=C2 InChI=1S/C22H17N3O5/c1-27-13-17(22(26)28-2)16-8-4-6-10-19(16)30-21-11-20(24-14-25-21)29-18-9-5-3-7-15(18)12-23/h3-11,13-14H,1-2H3/b17-13+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Azoxystrobin 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin 15Apr2010 2010 doi:10.2903/j.efsa.2010.1542
+Azoxystrobin 131860-33-8 single chemical entity Component is identical to the substance Azoxystrobin 131860-33-8 methyl (2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyacrylate Azoxystrobin C22H17N3O5 N#CC1=CC=CC=C1OC2=NC=NC(OC3=CC=CC=C3/C(C(OC)=O)=C\OC)=C2 InChI=1S/C22H17N3O5/c1-27-13-17(22(26)28-2)16-8-4-6-10-19(16)30-21-11-20(24-14-25-21)29-18-9-5-3-7-15(18)12-23/h3-11,13-14H,1-2H3/b17-13+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Azoxystrobin 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin 15Apr2010 2010 doi:10.2903/j.efsa.2010.1542
+Azoxystrobin 131860-33-8 single chemical entity Component is identical to the substance Azoxystrobin 131860-33-8 methyl (2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyacrylate Azoxystrobin C22H17N3O5 N#CC1=CC=CC=C1OC2=NC=NC(OC3=CC=CC=C3/C(C(OC)=O)=C\OC)=C2 InChI=1S/C22H17N3O5/c1-27-13-17(22(26)28-2)16-8-4-6-10-19(16)30-21-11-20(24-14-25-21)29-18-9-5-3-7-15(18)12-23/h3-11,13-14H,1-2H3/b17-13+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Azoxystrobin 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin 15Apr2010 2010 doi:10.2903/j.efsa.2010.1542
+Azoxystrobin 131860-33-8 single chemical entity Component is identical to the substance Azoxystrobin 131860-33-8 methyl (2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyacrylate Azoxystrobin C22H17N3O5 N#CC1=CC=CC=C1OC2=NC=NC(OC3=CC=CC=C3/C(C(OC)=O)=C\OC)=C2 InChI=1S/C22H17N3O5/c1-27-13-17(22(26)28-2)16-8-4-6-10-19(16)30-21-11-20(24-14-25-21)29-18-9-5-3-7-15(18)12-23/h3-11,13-14H,1-2H3/b17-13+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Azoxystrobin 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin 15Apr2010 2010 doi:10.2903/j.efsa.2010.1542
+Azoxystrobin 131860-33-8 single chemical entity Component is identical to the substance Azoxystrobin 131860-33-8 methyl (2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyacrylate Azoxystrobin C22H17N3O5 N#CC1=CC=CC=C1OC2=NC=NC(OC3=CC=CC=C3/C(C(OC)=O)=C\OC)=C2 InChI=1S/C22H17N3O5/c1-27-13-17(22(26)28-2)16-8-4-6-10-19(16)30-21-11-20(24-14-25-21)29-18-9-5-3-7-15(18)12-23/h3-11,13-14H,1-2H3/b17-13+ organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Positive small colonies RMS: The United Kingdom Azoxystrobin 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin 15Apr2010 2010 doi:10.2903/j.efsa.2010.1542
+Azoxystrobin 131860-33-8 single chemical entity Component is identical to the substance Azoxystrobin 131860-33-8 methyl (2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyacrylate Azoxystrobin C22H17N3O5 N#CC1=CC=CC=C1OC2=NC=NC(OC3=CC=CC=C3/C(C(OC)=O)=C\OC)=C2 InChI=1S/C22H17N3O5/c1-27-13-17(22(26)28-2)16-8-4-6-10-19(16)30-21-11-20(24-14-25-21)29-18-9-5-3-7-15(18)12-23/h3-11,13-14H,1-2H3/b17-13+ organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Positive small colonies RMS: The United Kingdom Azoxystrobin 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin 15Apr2010 2010 doi:10.2903/j.efsa.2010.1542
+Azoxystrobin 131860-33-8 single chemical entity Component is identical to the substance Azoxystrobin 131860-33-8 methyl (2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyacrylate Azoxystrobin C22H17N3O5 N#CC1=CC=CC=C1OC2=NC=NC(OC3=CC=CC=C3/C(C(OC)=O)=C\OC)=C2 InChI=1S/C22H17N3O5/c1-27-13-17(22(26)28-2)16-8-4-6-10-19(16)30-21-11-20(24-14-25-21)29-18-9-5-3-7-15(18)12-23/h3-11,13-14H,1-2H3/b17-13+ organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Sprague-Dawley Male oral: gavage 2.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Azoxystrobin 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin 15Apr2010 2010 doi:10.2903/j.efsa.2010.1542
+Azoxystrobin 131860-33-8 single chemical entity Component is identical to the substance Azoxystrobin 131860-33-8 methyl (2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyacrylate Azoxystrobin C22H17N3O5 N#CC1=CC=CC=C1OC2=NC=NC(OC3=CC=CC=C3/C(C(OC)=O)=C\OC)=C2 InChI=1S/C22H17N3O5/c1-27-13-17(22(26)28-2)16-8-4-6-10-19(16)30-21-11-20(24-14-25-21)29-18-9-5-3-7-15(18)12-23/h3-11,13-14H,1-2H3/b17-13+ organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Sprague-Dawley Male oral: gavage 16.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Azoxystrobin 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin 15Apr2010 2010 doi:10.2903/j.efsa.2010.1542
+Azoxystrobin 131860-33-8 single chemical entity Component is a metabolite of the substance (2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyprop-2-enoic acid (2Z)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-4-oxopent-2-enoic acid Not in list C22H15N3O5 CC(=O)\C=C(/C(=O)O)c3ccccc3Oc2cc(Oc1ccccc1C#N)ncn2 InChI=1/C22H15N3O5/c1-14(26)10-17(22(27)28)16-7-3-5-9-19(16)30-21-11-20(24-13-25-21)29-18-8-4-2-6-15(18)12-23/h2-11,13H,1H3,(H,27,28)/b17-10- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Azoxystrobin 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin 15Apr2010 2010 doi:10.2903/j.efsa.2010.1542
+Azoxystrobin 131860-33-8 single chemical entity Component is a metabolite of the substance (2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyprop-2-enoic acid (2Z)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-4-oxopent-2-enoic acid Not in list C22H15N3O5 CC(=O)\C=C(/C(=O)O)c3ccccc3Oc2cc(Oc1ccccc1C#N)ncn2 InChI=1/C22H15N3O5/c1-14(26)10-17(22(27)28)16-7-3-5-9-19(16)30-21-11-20(24-13-25-21)29-18-8-4-2-6-15(18)12-23/h2-11,13H,1H3,(H,27,28)/b17-10- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Azoxystrobin 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin 15Apr2010 2010 doi:10.2903/j.efsa.2010.1542
+Azoxystrobin 131860-33-8 single chemical entity Component is a metabolite of the substance (2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyprop-2-enoic acid (2Z)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-4-oxopent-2-enoic acid Not in list C22H15N3O5 CC(=O)\C=C(/C(=O)O)c3ccccc3Oc2cc(Oc1ccccc1C#N)ncn2 InChI=1/C22H15N3O5/c1-14(26)10-17(22(27)28)16-7-3-5-9-19(16)30-21-11-20(24-13-25-21)29-18-8-4-2-6-15(18)12-23/h2-11,13H,1H3,(H,27,28)/b17-10- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Azoxystrobin 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin 15Apr2010 2010 doi:10.2903/j.efsa.2010.1542
+Azoxystrobin 131860-33-8 single chemical entity Component is a metabolite of the substance (2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyprop-2-enoic acid (2Z)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-4-oxopent-2-enoic acid Not in list C22H15N3O5 CC(=O)\C=C(/C(=O)O)c3ccccc3Oc2cc(Oc1ccccc1C#N)ncn2 InChI=1/C22H15N3O5/c1-14(26)10-17(22(27)28)16-7-3-5-9-19(16)30-21-11-20(24-13-25-21)29-18-8-4-2-6-15(18)12-23/h2-11,13H,1H3,(H,27,28)/b17-10- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Azoxystrobin 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin 15Apr2010 2010 doi:10.2903/j.efsa.2010.1542
+Azoxystrobin 131860-33-8 single chemical entity Component is a metabolite of the substance (2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyprop-2-enoic acid (2Z)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-4-oxopent-2-enoic acid Not in list C22H15N3O5 CC(=O)\C=C(/C(=O)O)c3ccccc3Oc2cc(Oc1ccccc1C#N)ncn2 InChI=1/C22H15N3O5/c1-14(26)10-17(22(27)28)16-7-3-5-9-19(16)30-21-11-20(24-13-25-21)29-18-8-4-2-6-15(18)12-23/h2-11,13H,1H3,(H,27,28)/b17-10- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Azoxystrobin 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin 15Apr2010 2010 doi:10.2903/j.efsa.2010.1542
+Azoxystrobin 131860-33-8 single chemical entity Component is a metabolite of the substance (2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyprop-2-enoic acid (2Z)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-4-oxopent-2-enoic acid Not in list C22H15N3O5 CC(=O)\C=C(/C(=O)O)c3ccccc3Oc2cc(Oc1ccccc1C#N)ncn2 InChI=1/C22H15N3O5/c1-14(26)10-17(22(27)28)16-7-3-5-9-19(16)30-21-11-20(24-13-25-21)29-18-8-4-2-6-15(18)12-23/h2-11,13H,1H3,(H,27,28)/b17-10- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Azoxystrobin 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin 15Apr2010 2010 doi:10.2903/j.efsa.2010.1542
+Azoxystrobin 131860-33-8 single chemical entity Component is a metabolite of the substance (2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyprop-2-enoic acid (2Z)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-4-oxopent-2-enoic acid Not in list C22H15N3O5 CC(=O)\C=C(/C(=O)O)c3ccccc3Oc2cc(Oc1ccccc1C#N)ncn2 InChI=1/C22H15N3O5/c1-14(26)10-17(22(27)28)16-7-3-5-9-19(16)30-21-11-20(24-13-25-21)29-18-8-4-2-6-15(18)12-23/h2-11,13H,1H3,(H,27,28)/b17-10- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Azoxystrobin 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin 15Apr2010 2010 doi:10.2903/j.efsa.2010.1542
+Azoxystrobin 131860-33-8 single chemical entity Component is a metabolite of the substance (2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyprop-2-enoic acid (2Z)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-4-oxopent-2-enoic acid Not in list C22H15N3O5 CC(=O)\C=C(/C(=O)O)c3ccccc3Oc2cc(Oc1ccccc1C#N)ncn2 InChI=1/C22H15N3O5/c1-14(26)10-17(22(27)28)16-7-3-5-9-19(16)30-21-11-20(24-13-25-21)29-18-8-4-2-6-15(18)12-23/h2-11,13H,1H3,(H,27,28)/b17-10- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Azoxystrobin 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin 15Apr2010 2010 doi:10.2903/j.efsa.2010.1542
+Azoxystrobin 131860-33-8 single chemical entity Component is a metabolite of the substance (2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyprop-2-enoic acid (2Z)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-4-oxopent-2-enoic acid Not in list C22H15N3O5 CC(=O)\C=C(/C(=O)O)c3ccccc3Oc2cc(Oc1ccccc1C#N)ncn2 InChI=1/C22H15N3O5/c1-14(26)10-17(22(27)28)16-7-3-5-9-19(16)30-21-11-20(24-13-25-21)29-18-8-4-2-6-15(18)12-23/h2-11,13H,1H3,(H,27,28)/b17-10- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Azoxystrobin 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin 15Apr2010 2010 doi:10.2903/j.efsa.2010.1542
+Azoxystrobin 131860-33-8 single chemical entity Component is a metabolite of the substance (2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyprop-2-enoic acid (2Z)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-4-oxopent-2-enoic acid Not in list C22H15N3O5 CC(=O)\C=C(/C(=O)O)c3ccccc3Oc2cc(Oc1ccccc1C#N)ncn2 InChI=1/C22H15N3O5/c1-14(26)10-17(22(27)28)16-7-3-5-9-19(16)30-21-11-20(24-13-25-21)29-18-8-4-2-6-15(18)12-23/h2-11,13H,1H3,(H,27,28)/b17-10- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Azoxystrobin 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin 15Apr2010 2010 doi:10.2903/j.efsa.2010.1542
+Azoxystrobin 131860-33-8 single chemical entity Component is a metabolite of the substance (2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyprop-2-enoic acid (2Z)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-4-oxopent-2-enoic acid Not in list C22H15N3O5 CC(=O)\C=C(/C(=O)O)c3ccccc3Oc2cc(Oc1ccccc1C#N)ncn2 InChI=1/C22H15N3O5/c1-14(26)10-17(22(27)28)16-7-3-5-9-19(16)30-21-11-20(24-13-25-21)29-18-8-4-2-6-15(18)12-23/h2-11,13H,1H3,(H,27,28)/b17-10- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Azoxystrobin 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin 15Apr2010 2010 doi:10.2903/j.efsa.2010.1542
+Azoxystrobin 131860-33-8 single chemical entity Component is a metabolite of the substance (2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyprop-2-enoic acid (2Z)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-4-oxopent-2-enoic acid Not in list C22H15N3O5 CC(=O)\C=C(/C(=O)O)c3ccccc3Oc2cc(Oc1ccccc1C#N)ncn2 InChI=1/C22H15N3O5/c1-14(26)10-17(22(27)28)16-7-3-5-9-19(16)30-21-11-20(24-13-25-21)29-18-8-4-2-6-15(18)12-23/h2-11,13H,1H3,(H,27,28)/b17-10- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Azoxystrobin 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin 15Apr2010 2010 doi:10.2903/j.efsa.2010.1542
+L-ascorbic acid 200-066-2 50-81-7 single chemical entity Component is identical to the substance L-ascorbic acid 200-066-2 50-81-7 (2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one L-ascorbic acid C6H8O6 C(C(C1C(=C(C(=O)O1)O)O)O)O InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: The Netherlands L-ascorbic acid 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance L-ascorbic acid 25Apr2013 2013 doi: 10.2903/j.efsa.2013.3197
+L-ascorbic acid 200-066-2 50-81-7 single chemical entity Component is identical to the substance L-ascorbic acid 200-066-2 50-81-7 (2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one L-ascorbic acid C6H8O6 C(C(C1C(=C(C(=O)O1)O)O)O)O InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: The Netherlands L-ascorbic acid 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance L-ascorbic acid 25Apr2013 2013 doi: 10.2903/j.efsa.2013.3197
+L-ascorbic acid 200-066-2 50-81-7 single chemical entity Component is identical to the substance L-ascorbic acid 200-066-2 50-81-7 (2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one L-ascorbic acid C6H8O6 C(C(C1C(=C(C(=O)O1)O)O)O)O InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Ambiguous RMS: The Netherlands L-ascorbic acid 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance L-ascorbic acid 25Apr2013 2013 doi: 10.2903/j.efsa.2013.3197
+L-ascorbic acid 200-066-2 50-81-7 single chemical entity Component is identical to the substance L-ascorbic acid 200-066-2 50-81-7 (2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one L-ascorbic acid C6H8O6 C(C(C1C(=C(C(=O)O1)O)O)O)O InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: The Netherlands L-ascorbic acid 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance L-ascorbic acid 25Apr2013 2013 doi: 10.2903/j.efsa.2013.3197
+L-ascorbic acid 200-066-2 50-81-7 single chemical entity Component is identical to the substance L-ascorbic acid 200-066-2 50-81-7 (2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one L-ascorbic acid C6H8O6 C(C(C1C(=C(C(=O)O1)O)O)O)O InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: The Netherlands L-ascorbic acid 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance L-ascorbic acid 25Apr2013 2013 doi: 10.2903/j.efsa.2013.3197
+L-ascorbic acid 200-066-2 50-81-7 single chemical entity Component is identical to the substance L-ascorbic acid 200-066-2 50-81-7 (2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one L-ascorbic acid C6H8O6 C(C(C1C(=C(C(=O)O1)O)O)O)O InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: The Netherlands L-ascorbic acid 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance L-ascorbic acid 25Apr2013 2013 doi: 10.2903/j.efsa.2013.3197
+L-ascorbic acid 200-066-2 50-81-7 single chemical entity Component is identical to the substance L-ascorbic acid 200-066-2 50-81-7 (2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one L-ascorbic acid C6H8O6 C(C(C1C(=C(C(=O)O1)O)O)O)O InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: The Netherlands L-ascorbic acid 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance L-ascorbic acid 25Apr2013 2013 doi: 10.2903/j.efsa.2013.3197
+L-ascorbic acid 200-066-2 50-81-7 single chemical entity Component is identical to the substance L-ascorbic acid 200-066-2 50-81-7 (2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one L-ascorbic acid C6H8O6 C(C(C1C(=C(C(=O)O1)O)O)O)O InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: The Netherlands L-ascorbic acid 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance L-ascorbic acid 25Apr2013 2013 doi: 10.2903/j.efsa.2013.3197
+L-ascorbic acid 200-066-2 50-81-7 single chemical entity Component is identical to the substance L-ascorbic acid 200-066-2 50-81-7 (2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one L-ascorbic acid C6H8O6 C(C(C1C(=C(C(=O)O1)O)O)O)O InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: The Netherlands L-ascorbic acid 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance L-ascorbic acid 25Apr2013 2013 doi: 10.2903/j.efsa.2013.3197
+L-ascorbic acid 200-066-2 50-81-7 single chemical entity Component is identical to the substance L-ascorbic acid 200-066-2 50-81-7 (2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one L-ascorbic acid C6H8O6 C(C(C1C(=C(C(=O)O1)O)O)O)O InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Ambiguous RMS: The Netherlands L-ascorbic acid 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance L-ascorbic acid 25Apr2013 2013 doi: 10.2903/j.efsa.2013.3197
+L-ascorbic acid 200-066-2 50-81-7 single chemical entity Component is identical to the substance L-ascorbic acid 200-066-2 50-81-7 (2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one L-ascorbic acid C6H8O6 C(C(C1C(=C(C(=O)O1)O)O)O)O InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: The Netherlands L-ascorbic acid 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance L-ascorbic acid 25Apr2013 2013 doi: 10.2903/j.efsa.2013.3197
+L-ascorbic acid 200-066-2 50-81-7 single chemical entity Component is identical to the substance L-ascorbic acid 200-066-2 50-81-7 (2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one L-ascorbic acid C6H8O6 C(C(C1C(=C(C(=O)O1)O)O)O)O InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data with Negative no information RMS: The Netherlands L-ascorbic acid 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance L-ascorbic acid 25Apr2013 2013 doi: 10.2903/j.efsa.2013.3197
+L-ascorbic acid 200-066-2 50-81-7 single chemical entity Component is identical to the substance L-ascorbic acid 200-066-2 50-81-7 (2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one L-ascorbic acid C6H8O6 C(C(C1C(=C(C(=O)O1)O)O)O)O InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data without Negative no information RMS: The Netherlands L-ascorbic acid 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance L-ascorbic acid 25Apr2013 2013 doi: 10.2903/j.efsa.2013.3197
+L-ascorbic acid 200-066-2 50-81-7 single chemical entity Component is identical to the substance L-ascorbic acid 200-066-2 50-81-7 (2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one L-ascorbic acid C6H8O6 C(C(C1C(=C(C(=O)O1)O)O)O)O InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Human (as organism) Not reported Not reported no data without Positive RMS: The Netherlands L-ascorbic acid 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance L-ascorbic acid 25Apr2013 2013 doi: 10.2903/j.efsa.2013.3197
+L-ascorbic acid 200-066-2 50-81-7 single chemical entity Component is identical to the substance L-ascorbic acid 200-066-2 50-81-7 (2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one L-ascorbic acid C6H8O6 C(C(C1C(=C(C(=O)O1)O)O)O)O InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) Yes Acceptable Hamster (as animal) CHO Not reported no data with Positive RMS: The Netherlands L-ascorbic acid 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance L-ascorbic acid 25Apr2013 2013 doi: 10.2903/j.efsa.2013.3197
+L-ascorbic acid 200-066-2 50-81-7 single chemical entity Component is identical to the substance L-ascorbic acid 200-066-2 50-81-7 (2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one L-ascorbic acid C6H8O6 C(C(C1C(=C(C(=O)O1)O)O)O)O InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) Yes Acceptable Hamster (as animal) CHO Not reported no data without Positive RMS: The Netherlands L-ascorbic acid 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance L-ascorbic acid 25Apr2013 2013 doi: 10.2903/j.efsa.2013.3197
+L-ascorbic acid 200-066-2 50-81-7 single chemical entity Component is identical to the substance L-ascorbic acid 200-066-2 50-81-7 (2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one L-ascorbic acid C6H8O6 C(C(C1C(=C(C(=O)O1)O)O)O)O InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) Yes Acceptable Human (as organism) lymphocytes Not reported no data without Positive RMS: The Netherlands L-ascorbic acid 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance L-ascorbic acid 25Apr2013 2013 doi: 10.2903/j.efsa.2013.3197
+L-ascorbic acid 200-066-2 50-81-7 single chemical entity Component is identical to the substance L-ascorbic acid 200-066-2 50-81-7 (2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one L-ascorbic acid C6H8O6 C(C(C1C(=C(C(=O)O1)O)O)O)O InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vivo No guideline available Not reported Not applicable Acceptable Hamster (as animal) Not reported No data Not reported no data not applicable Negative RMS: The Netherlands L-ascorbic acid 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance L-ascorbic acid 25Apr2013 2013 doi: 10.2903/j.efsa.2013.3197
+L-ascorbic acid 200-066-2 50-81-7 single chemical entity Component is identical to the substance L-ascorbic acid 200-066-2 50-81-7 (2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one L-ascorbic acid C6H8O6 C(C(C1C(=C(C(=O)O1)O)O)O)O InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable House mouse (as animal) CD-1 No data Not reported no data not applicable Negative RMS: The Netherlands L-ascorbic acid 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance L-ascorbic acid 25Apr2013 2013 doi: 10.2903/j.efsa.2013.3197
+L-ascorbic acid 200-066-2 50-81-7 single chemical entity Component is identical to the substance L-ascorbic acid 200-066-2 50-81-7 (2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one L-ascorbic acid C6H8O6 C(C(C1C(=C(C(=O)O1)O)O)O)O InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable House mouse (as animal) B6C3F1 No data Not reported no data not applicable Negative RMS: The Netherlands L-ascorbic acid 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance L-ascorbic acid 25Apr2013 2013 doi: 10.2903/j.efsa.2013.3197
+Azadirachtin A 11141-17-6 complex product: derived from botanical sources Component is the active ingredient of the mixture or formulation Azadirachtin extract (Trifolio-M GmbH source) methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate Not in list C35H44O16 C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany Azadirachtin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin 17Mar2011 2011 doi:10.2903/j.efsa.2011.1858
+Azadirachtin A 11141-17-6 complex product: derived from botanical sources Component is the active ingredient of the mixture or formulation Azadirachtin extract (Trifolio-M GmbH source) methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate Not in list C35H44O16 C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany Azadirachtin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin 17Mar2011 2011 doi:10.2903/j.efsa.2011.1858
+Azadirachtin A 11141-17-6 complex product: derived from botanical sources Component is the active ingredient of the mixture or formulation Azadirachtin extract (Trifolio-M GmbH source) methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate Not in list C35H44O16 C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany Azadirachtin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin 17Mar2011 2011 doi:10.2903/j.efsa.2011.1858
+Azadirachtin A 11141-17-6 complex product: derived from botanical sources Component is the active ingredient of the mixture or formulation Azadirachtin extract (Trifolio-M GmbH source) methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate Not in list C35H44O16 C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany Azadirachtin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin 17Mar2011 2011 doi:10.2903/j.efsa.2011.1858
+Azadirachtin A 11141-17-6 complex product: derived from botanical sources Component is the active ingredient of the mixture or formulation Azadirachtin extract (Trifolio-M GmbH source) methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate Not in list C35H44O16 C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Germany Azadirachtin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin 17Mar2011 2011 doi:10.2903/j.efsa.2011.1858
+Azadirachtin A 11141-17-6 complex product: derived from botanical sources Component is the active ingredient of the mixture or formulation Azadirachtin extract (Trifolio-M GmbH source) methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate Not in list C35H44O16 C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany Azadirachtin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin 17Mar2011 2011 doi:10.2903/j.efsa.2011.1858
+Azadirachtin A 11141-17-6 complex product: derived from botanical sources Component is the active ingredient of the mixture or formulation Azadirachtin extract (Trifolio-M GmbH source) methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate Not in list C35H44O16 C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany Azadirachtin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin 17Mar2011 2011 doi:10.2903/j.efsa.2011.1858
+Azadirachtin A 11141-17-6 complex product: derived from botanical sources Component is the active ingredient of the mixture or formulation Azadirachtin extract (Trifolio-M GmbH source) methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate Not in list C35H44O16 C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany Azadirachtin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin 17Mar2011 2011 doi:10.2903/j.efsa.2011.1858
+Azadirachtin A 11141-17-6 complex product: derived from botanical sources Component is the active ingredient of the mixture or formulation Azadirachtin extract (Trifolio-M GmbH source) methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate Not in list C35H44O16 C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Germany Azadirachtin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin 17Mar2011 2011 doi:10.2903/j.efsa.2011.1858
+Azadirachtin A 11141-17-6 complex product: derived from botanical sources Component is the active ingredient of the mixture or formulation Azadirachtin extract (Trifolio-M GmbH source) methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate Not in list C35H44O16 C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany Azadirachtin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin 17Mar2011 2011 doi:10.2903/j.efsa.2011.1858
+Azadirachtin A 11141-17-6 complex product: microorganisms or derived from microorganisms Component is the active ingredient of the mixture or formulation Azadirachtin extract (Sipcam S.p.A source) methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate Not in list C35H44O16 C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany Azadirachtin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin 17Mar2011 2011 doi:10.2903/j.efsa.2011.1858
+Azadirachtin A 11141-17-6 complex product: microorganisms or derived from microorganisms Component is the active ingredient of the mixture or formulation Azadirachtin extract (Sipcam S.p.A source) methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate Not in list C35H44O16 C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany Azadirachtin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin 17Mar2011 2011 doi:10.2903/j.efsa.2011.1858
+Azadirachtin A 11141-17-6 complex product: microorganisms or derived from microorganisms Component is the active ingredient of the mixture or formulation Azadirachtin extract (Sipcam S.p.A source) methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate Not in list C35H44O16 C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany Azadirachtin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin 17Mar2011 2011 doi:10.2903/j.efsa.2011.1858
+Azadirachtin A 11141-17-6 complex product: microorganisms or derived from microorganisms Component is the active ingredient of the mixture or formulation Azadirachtin extract (Sipcam S.p.A source) methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate Not in list C35H44O16 C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany Azadirachtin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin 17Mar2011 2011 doi:10.2903/j.efsa.2011.1858
+Azadirachtin A 11141-17-6 complex product: microorganisms or derived from microorganisms Component is the active ingredient of the mixture or formulation Azadirachtin extract (Sipcam S.p.A source) methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate Not in list C35H44O16 C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany Azadirachtin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin 17Mar2011 2011 doi:10.2903/j.efsa.2011.1858
+Azadirachtin A 11141-17-6 complex product: microorganisms or derived from microorganisms Component is the active ingredient of the mixture or formulation Azadirachtin extract (Sipcam S.p.A source) methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate Not in list C35H44O16 C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany Azadirachtin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin 17Mar2011 2011 doi:10.2903/j.efsa.2011.1858
+Azadirachtin A 11141-17-6 complex product: microorganisms or derived from microorganisms Component is the active ingredient of the mixture or formulation Azadirachtin extract (Sipcam S.p.A source) methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate Not in list C35H44O16 C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany Azadirachtin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin 17Mar2011 2011 doi:10.2903/j.efsa.2011.1858
+Azadirachtin A 11141-17-6 complex product: microorganisms or derived from microorganisms Component is the active ingredient of the mixture or formulation Azadirachtin extract (Sipcam S.p.A source) methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate Not in list C35H44O16 C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany Azadirachtin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin 17Mar2011 2011 doi:10.2903/j.efsa.2011.1858
+Azadirachtin A 11141-17-6 complex product: microorganisms or derived from microorganisms Component is the active ingredient of the mixture or formulation Azadirachtin extract (Sipcam S.p.A source) methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate Not in list C35H44O16 C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Germany Azadirachtin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin 17Mar2011 2011 doi:10.2903/j.efsa.2011.1858
+Azadirachtin A 11141-17-6 complex product: microorganisms or derived from microorganisms Component is the active ingredient of the mixture or formulation Azadirachtin extract (Sipcam S.p.A source) methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate Not in list C35H44O16 C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Germany Azadirachtin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin 17Mar2011 2011 doi:10.2903/j.efsa.2011.1858
+Azadirachtin A 11141-17-6 complex product: derived from botanical sources Component is the active ingredient of the mixture or formulation Azadirachtin extract (Mitsui AgriScience International S.A/B.V source) methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate Not in list C35H44O16 C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany Azadirachtin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin 17Mar2011 2011 doi:10.2903/j.efsa.2011.1858
+Azadirachtin A 11141-17-6 complex product: derived from botanical sources Component is the active ingredient of the mixture or formulation Azadirachtin extract (Mitsui AgriScience International S.A/B.V source) methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate Not in list C35H44O16 C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany Azadirachtin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin 17Mar2011 2011 doi:10.2903/j.efsa.2011.1858
+Azadirachtin A 11141-17-6 complex product: derived from botanical sources Component is the active ingredient of the mixture or formulation Azadirachtin extract (Mitsui AgriScience International S.A/B.V source) methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate Not in list C35H44O16 C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany Azadirachtin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin 17Mar2011 2011 doi:10.2903/j.efsa.2011.1858
+Azadirachtin A 11141-17-6 complex product: derived from botanical sources Component is the active ingredient of the mixture or formulation Azadirachtin extract (Mitsui AgriScience International S.A/B.V source) methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate Not in list C35H44O16 C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany Azadirachtin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin 17Mar2011 2011 doi:10.2903/j.efsa.2011.1858
+Azadirachtin A 11141-17-6 complex product: derived from botanical sources Component is the active ingredient of the mixture or formulation Azadirachtin extract (Mitsui AgriScience International S.A/B.V source) methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate Not in list C35H44O16 C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany Azadirachtin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin 17Mar2011 2011 doi:10.2903/j.efsa.2011.1858
+Azadirachtin A 11141-17-6 complex product: derived from botanical sources Component is the active ingredient of the mixture or formulation Azadirachtin extract (Mitsui AgriScience International S.A/B.V source) methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate Not in list C35H44O16 C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany Azadirachtin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin 17Mar2011 2011 doi:10.2903/j.efsa.2011.1858
+Azadirachtin A 11141-17-6 complex product: derived from botanical sources Component is the active ingredient of the mixture or formulation Azadirachtin extract (Mitsui AgriScience International S.A/B.V source) methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate Not in list C35H44O16 C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany Azadirachtin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin 17Mar2011 2011 doi:10.2903/j.efsa.2011.1858
+Azadirachtin A 11141-17-6 complex product: derived from botanical sources Component is the active ingredient of the mixture or formulation Azadirachtin extract (Mitsui AgriScience International S.A/B.V source) methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate Not in list C35H44O16 C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Germany Azadirachtin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin 17Mar2011 2011 doi:10.2903/j.efsa.2011.1858
+Azadirachtin A 11141-17-6 complex product: derived from botanical sources Component is the active ingredient of the mixture or formulation Azadirachtin extract (Mitsui AgriScience International S.A/B.V source) methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate Not in list C35H44O16 C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany Azadirachtin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin 17Mar2011 2011 doi:10.2903/j.efsa.2011.1858
+Azadirachtin A 11141-17-6 complex product: derived from botanical sources Component is the active ingredient of the mixture or formulation Azadirachtin extract (Mitsui AgriScience International S.A/B.V source) methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate Not in list C35H44O16 C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Germany Azadirachtin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin 17Mar2011 2011 doi:10.2903/j.efsa.2011.1858
+Azadirachtin A 11141-17-6 complex product: derived from botanical sources Component is the active ingredient of the mixture or formulation Azadirachtin extract (Mitsui AgriScience International S.A/B.V source) methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate Not in list C35H44O16 C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+ organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Germany Azadirachtin (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin 17Mar2011 2011 doi:10.2903/j.efsa.2011.1858
+Azadirachtin A 11141-17-6 complex product: derived from botanical sources Component is the active ingredient of the mixture or formulation Azadirachtin extract (Mitsui AgriScience International S.A/B.V source) methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate Not in list C35H44O16 C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+ organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Germany Azadirachtin (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin 17Mar2011 2011 doi:10.2903/j.efsa.2011.1858
+Azadirachtin A 11141-17-6 complex product: derived from botanical sources Component is the active ingredient of the mixture or formulation Azadirachtin extract (Mitsui AgriScience International S.A/B.V source) methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate Not in list C35H44O16 C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+ organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) ICR 10 Male/Female oral: unspecified 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Germany Azadirachtin (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin 17Mar2011 2011 doi:10.2903/j.efsa.2011.1858
+Azadirachtin A 11141-17-6 complex product: derived from botanical sources Component is the active ingredient of the mixture or formulation Azadirachtin extract (Mitsui AgriScience International S.A/B.V source) methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate Not in list C35H44O16 C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+ organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) ICR 10 Male/Female oral: unspecified 72.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Germany Azadirachtin (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin 17Mar2011 2011 doi:10.2903/j.efsa.2011.1858
+Azadirachtin A 11141-17-6 complex product: derived from botanical sources Component is the active ingredient of the mixture or formulation Azadirachtin extract (Mitsui AgriScience International S.A/B.V source) methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate Not in list C35H44O16 C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+ organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) ICR 10 Male/Female oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Germany Azadirachtin (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin 17Mar2011 2011 doi:10.2903/j.efsa.2011.1858
+Benfluralin 217-465-2 1861-40-1 single chemical entity Component is identical to the substance Benfluralin 217-465-2 1861-40-1 N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline Benfluralin C13H16F3N3O4 CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Belgium Benfluralin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin 28Jul2008 2008 doi:10.2903/j.efsa.2008.127r
+Benfluralin 217-465-2 1861-40-1 single chemical entity Component is identical to the substance Benfluralin 217-465-2 1861-40-1 N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline Benfluralin C13H16F3N3O4 CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Belgium Benfluralin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin 28Jul2008 2008 doi:10.2903/j.efsa.2008.127r
+Benfluralin 217-465-2 1861-40-1 single chemical entity Component is identical to the substance Benfluralin 217-465-2 1861-40-1 N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline Benfluralin C13H16F3N3O4 CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Belgium Benfluralin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin 28Jul2008 2008 doi:10.2903/j.efsa.2008.127r
+Benfluralin 217-465-2 1861-40-1 single chemical entity Component is identical to the substance Benfluralin 217-465-2 1861-40-1 N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline Benfluralin C13H16F3N3O4 CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Belgium Benfluralin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin 28Jul2008 2008 doi:10.2903/j.efsa.2008.127r
+Benfluralin 217-465-2 1861-40-1 single chemical entity Component is identical to the substance Benfluralin 217-465-2 1861-40-1 N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline Benfluralin C13H16F3N3O4 CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: Belgium Benfluralin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin 28Jul2008 2008 doi:10.2903/j.efsa.2008.127r
+Benfluralin 217-465-2 1861-40-1 single chemical entity Component is identical to the substance Benfluralin 217-465-2 1861-40-1 N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline Benfluralin C13H16F3N3O4 CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) C3052 Not reported yes with Negative RMS: Belgium Benfluralin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin 28Jul2008 2008 doi:10.2903/j.efsa.2008.127r
+Benfluralin 217-465-2 1861-40-1 single chemical entity Component is identical to the substance Benfluralin 217-465-2 1861-40-1 N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline Benfluralin C13H16F3N3O4 CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: Belgium Benfluralin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin 28Jul2008 2008 doi:10.2903/j.efsa.2008.127r
+Benfluralin 217-465-2 1861-40-1 single chemical entity Component is identical to the substance Benfluralin 217-465-2 1861-40-1 N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline Benfluralin C13H16F3N3O4 CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: Belgium Benfluralin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin 28Jul2008 2008 doi:10.2903/j.efsa.2008.127r
+Benfluralin 217-465-2 1861-40-1 single chemical entity Component is identical to the substance Benfluralin 217-465-2 1861-40-1 N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline Benfluralin C13H16F3N3O4 CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Belgium Benfluralin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin 28Jul2008 2008 doi:10.2903/j.efsa.2008.127r
+Benfluralin 217-465-2 1861-40-1 single chemical entity Component is identical to the substance Benfluralin 217-465-2 1861-40-1 N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline Benfluralin C13H16F3N3O4 CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Belgium Benfluralin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin 28Jul2008 2008 doi:10.2903/j.efsa.2008.127r
+Benfluralin 217-465-2 1861-40-1 single chemical entity Component is identical to the substance Benfluralin 217-465-2 1861-40-1 N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline Benfluralin C13H16F3N3O4 CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 Not reported yes without Negative RMS: Belgium Benfluralin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin 28Jul2008 2008 doi:10.2903/j.efsa.2008.127r
+Benfluralin 217-465-2 1861-40-1 single chemical entity Component is identical to the substance Benfluralin 217-465-2 1861-40-1 N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline Benfluralin C13H16F3N3O4 CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) G46 Not reported yes with Negative RMS: Belgium Benfluralin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin 28Jul2008 2008 doi:10.2903/j.efsa.2008.127r
+Benfluralin 217-465-2 1861-40-1 single chemical entity Component is identical to the substance Benfluralin 217-465-2 1861-40-1 N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline Benfluralin C13H16F3N3O4 CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 Not reported yes with Negative RMS: Belgium Benfluralin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin 28Jul2008 2008 doi:10.2903/j.efsa.2008.127r
+Benfluralin 217-465-2 1861-40-1 single chemical entity Component is identical to the substance Benfluralin 217-465-2 1861-40-1 N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline Benfluralin C13H16F3N3O4 CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) C3052 Not reported yes without Negative RMS: Belgium Benfluralin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin 28Jul2008 2008 doi:10.2903/j.efsa.2008.127r
+Benfluralin 217-465-2 1861-40-1 single chemical entity Component is identical to the substance Benfluralin 217-465-2 1861-40-1 N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline Benfluralin C13H16F3N3O4 CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Belgium Benfluralin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin 28Jul2008 2008 doi:10.2903/j.efsa.2008.127r
+Benfluralin 217-465-2 1861-40-1 single chemical entity Component is identical to the substance Benfluralin 217-465-2 1861-40-1 N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline Benfluralin C13H16F3N3O4 CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Belgium Benfluralin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin 28Jul2008 2008 doi:10.2903/j.efsa.2008.127r
+Benfluralin 217-465-2 1861-40-1 single chemical entity Component is identical to the substance Benfluralin 217-465-2 1861-40-1 N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline Benfluralin C13H16F3N3O4 CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: Belgium Benfluralin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin 28Jul2008 2008 doi:10.2903/j.efsa.2008.127r
+Benfluralin 217-465-2 1861-40-1 single chemical entity Component is identical to the substance Benfluralin 217-465-2 1861-40-1 N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline Benfluralin C13H16F3N3O4 CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) C3076 Not reported yes without Negative RMS: Belgium Benfluralin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin 28Jul2008 2008 doi:10.2903/j.efsa.2008.127r
+Benfluralin 217-465-2 1861-40-1 single chemical entity Component is identical to the substance Benfluralin 217-465-2 1861-40-1 N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline Benfluralin C13H16F3N3O4 CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) C3076 Not reported yes with Negative RMS: Belgium Benfluralin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin 28Jul2008 2008 doi:10.2903/j.efsa.2008.127r
+Benfluralin 217-465-2 1861-40-1 single chemical entity Component is identical to the substance Benfluralin 217-465-2 1861-40-1 N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline Benfluralin C13H16F3N3O4 CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) G46 Not reported yes without Negative RMS: Belgium Benfluralin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin 28Jul2008 2008 doi:10.2903/j.efsa.2008.127r
+Azimsulfuron 601-676-5 120162-55-2 single chemical entity Component is identical to the substance Azimsulfuron 601-676-5 120162-55-2 N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide Azimsulfuron C13H16N10O5S Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(OC)cc(OC)n3 InChI=1S/C13H16N10O5S/c1-22-11(7(6-14-22)10-18-21-23(2)19-10)29(25,26)20-13(24)17-12-15-8(27-3)5-9(16-12)28-4/h5-6H,1-4H3,(H2,15,16,17,20,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Sweden - CoRMS: Slovenia Azimsulfuron (Corrigendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron 26Mar2010 2010 doi:10.2903/j.efsa.2010.1554
+Azimsulfuron 601-676-5 120162-55-2 single chemical entity Component is identical to the substance Azimsulfuron 601-676-5 120162-55-2 N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide Azimsulfuron C13H16N10O5S Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(OC)cc(OC)n3 InChI=1S/C13H16N10O5S/c1-22-11(7(6-14-22)10-18-21-23(2)19-10)29(25,26)20-13(24)17-12-15-8(27-3)5-9(16-12)28-4/h5-6H,1-4H3,(H2,15,16,17,20,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Sweden - CoRMS: Slovenia Azimsulfuron (Corrigendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron 26Mar2010 2010 doi:10.2903/j.efsa.2010.1554
+Azimsulfuron 601-676-5 120162-55-2 single chemical entity Component is identical to the substance Azimsulfuron 601-676-5 120162-55-2 N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide Azimsulfuron C13H16N10O5S Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(OC)cc(OC)n3 InChI=1S/C13H16N10O5S/c1-22-11(7(6-14-22)10-18-21-23(2)19-10)29(25,26)20-13(24)17-12-15-8(27-3)5-9(16-12)28-4/h5-6H,1-4H3,(H2,15,16,17,20,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Sweden - CoRMS: Slovenia Azimsulfuron (Corrigendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron 26Mar2010 2010 doi:10.2903/j.efsa.2010.1554
+Azimsulfuron 601-676-5 120162-55-2 single chemical entity Component is identical to the substance Azimsulfuron 601-676-5 120162-55-2 N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide Azimsulfuron C13H16N10O5S Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(OC)cc(OC)n3 InChI=1S/C13H16N10O5S/c1-22-11(7(6-14-22)10-18-21-23(2)19-10)29(25,26)20-13(24)17-12-15-8(27-3)5-9(16-12)28-4/h5-6H,1-4H3,(H2,15,16,17,20,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes without Negative RMS: Sweden - CoRMS: Slovenia Azimsulfuron (Corrigendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron 26Mar2010 2010 doi:10.2903/j.efsa.2010.1554
+Azimsulfuron 601-676-5 120162-55-2 single chemical entity Component is identical to the substance Azimsulfuron 601-676-5 120162-55-2 N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide Azimsulfuron C13H16N10O5S Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(OC)cc(OC)n3 InChI=1S/C13H16N10O5S/c1-22-11(7(6-14-22)10-18-21-23(2)19-10)29(25,26)20-13(24)17-12-15-8(27-3)5-9(16-12)28-4/h5-6H,1-4H3,(H2,15,16,17,20,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Sweden - CoRMS: Slovenia Azimsulfuron (Corrigendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron 26Mar2010 2010 doi:10.2903/j.efsa.2010.1554
+Azimsulfuron 601-676-5 120162-55-2 single chemical entity Component is identical to the substance Azimsulfuron 601-676-5 120162-55-2 N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide Azimsulfuron C13H16N10O5S Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(OC)cc(OC)n3 InChI=1S/C13H16N10O5S/c1-22-11(7(6-14-22)10-18-21-23(2)19-10)29(25,26)20-13(24)17-12-15-8(27-3)5-9(16-12)28-4/h5-6H,1-4H3,(H2,15,16,17,20,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Sweden - CoRMS: Slovenia Azimsulfuron (Corrigendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron 26Mar2010 2010 doi:10.2903/j.efsa.2010.1554
+Azimsulfuron 601-676-5 120162-55-2 single chemical entity Component is identical to the substance Azimsulfuron 601-676-5 120162-55-2 N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide Azimsulfuron C13H16N10O5S Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(OC)cc(OC)n3 InChI=1S/C13H16N10O5S/c1-22-11(7(6-14-22)10-18-21-23(2)19-10)29(25,26)20-13(24)17-12-15-8(27-3)5-9(16-12)28-4/h5-6H,1-4H3,(H2,15,16,17,20,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes with Negative RMS: Sweden - CoRMS: Slovenia Azimsulfuron (Corrigendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron 26Mar2010 2010 doi:10.2903/j.efsa.2010.1554
+Azimsulfuron 601-676-5 120162-55-2 single chemical entity Component is identical to the substance Azimsulfuron 601-676-5 120162-55-2 N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide Azimsulfuron C13H16N10O5S Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(OC)cc(OC)n3 InChI=1S/C13H16N10O5S/c1-22-11(7(6-14-22)10-18-21-23(2)19-10)29(25,26)20-13(24)17-12-15-8(27-3)5-9(16-12)28-4/h5-6H,1-4H3,(H2,15,16,17,20,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Sweden - CoRMS: Slovenia Azimsulfuron (Corrigendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron 26Mar2010 2010 doi:10.2903/j.efsa.2010.1554
+Azimsulfuron 601-676-5 120162-55-2 single chemical entity Component is identical to the substance Azimsulfuron 601-676-5 120162-55-2 N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide Azimsulfuron C13H16N10O5S Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(OC)cc(OC)n3 InChI=1S/C13H16N10O5S/c1-22-11(7(6-14-22)10-18-21-23(2)19-10)29(25,26)20-13(24)17-12-15-8(27-3)5-9(16-12)28-4/h5-6H,1-4H3,(H2,15,16,17,20,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Sweden - CoRMS: Slovenia Azimsulfuron (Corrigendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron 26Mar2010 2010 doi:10.2903/j.efsa.2010.1554
+Azimsulfuron 601-676-5 120162-55-2 single chemical entity Component is identical to the substance Azimsulfuron 601-676-5 120162-55-2 N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide Azimsulfuron C13H16N10O5S Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(OC)cc(OC)n3 InChI=1S/C13H16N10O5S/c1-22-11(7(6-14-22)10-18-21-23(2)19-10)29(25,26)20-13(24)17-12-15-8(27-3)5-9(16-12)28-4/h5-6H,1-4H3,(H2,15,16,17,20,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Sweden - CoRMS: Slovenia Azimsulfuron (Corrigendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron 26Mar2010 2010 doi:10.2903/j.efsa.2010.1554
+Azimsulfuron 601-676-5 120162-55-2 single chemical entity Component is identical to the substance Azimsulfuron 601-676-5 120162-55-2 N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide Azimsulfuron C13H16N10O5S Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(OC)cc(OC)n3 InChI=1S/C13H16N10O5S/c1-22-11(7(6-14-22)10-18-21-23(2)19-10)29(25,26)20-13(24)17-12-15-8(27-3)5-9(16-12)28-4/h5-6H,1-4H3,(H2,15,16,17,20,24) organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes without Negative RMS: Sweden - CoRMS: Slovenia Azimsulfuron (Corrigendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron 26Mar2010 2010 doi:10.2903/j.efsa.2010.1554
+Azimsulfuron 601-676-5 120162-55-2 single chemical entity Component is identical to the substance Azimsulfuron 601-676-5 120162-55-2 N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide Azimsulfuron C13H16N10O5S Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(OC)cc(OC)n3 InChI=1S/C13H16N10O5S/c1-22-11(7(6-14-22)10-18-21-23(2)19-10)29(25,26)20-13(24)17-12-15-8(27-3)5-9(16-12)28-4/h5-6H,1-4H3,(H2,15,16,17,20,24) organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes without Negative RMS: Sweden - CoRMS: Slovenia Azimsulfuron (Corrigendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron 26Mar2010 2010 doi:10.2903/j.efsa.2010.1554
+Azimsulfuron 601-676-5 120162-55-2 single chemical entity Component is identical to the substance Azimsulfuron 601-676-5 120162-55-2 N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide Azimsulfuron C13H16N10O5S Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(OC)cc(OC)n3 InChI=1S/C13H16N10O5S/c1-22-11(7(6-14-22)10-18-21-23(2)19-10)29(25,26)20-13(24)17-12-15-8(27-3)5-9(16-12)28-4/h5-6H,1-4H3,(H2,15,16,17,20,24) organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes with Negative RMS: Sweden - CoRMS: Slovenia Azimsulfuron (Corrigendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron 26Mar2010 2010 doi:10.2903/j.efsa.2010.1554
+Azimsulfuron 601-676-5 120162-55-2 single chemical entity Component is identical to the substance Azimsulfuron 601-676-5 120162-55-2 N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide Azimsulfuron C13H16N10O5S Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(OC)cc(OC)n3 InChI=1S/C13H16N10O5S/c1-22-11(7(6-14-22)10-18-21-23(2)19-10)29(25,26)20-13(24)17-12-15-8(27-3)5-9(16-12)28-4/h5-6H,1-4H3,(H2,15,16,17,20,24) organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes with Negative RMS: Sweden - CoRMS: Slovenia Azimsulfuron (Corrigendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron 26Mar2010 2010 doi:10.2903/j.efsa.2010.1554
+Azimsulfuron 601-676-5 120162-55-2 single chemical entity Component is identical to the substance Azimsulfuron 601-676-5 120162-55-2 N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide Azimsulfuron C13H16N10O5S Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(OC)cc(OC)n3 InChI=1S/C13H16N10O5S/c1-22-11(7(6-14-22)10-18-21-23(2)19-10)29(25,26)20-13(24)17-12-15-8(27-3)5-9(16-12)28-4/h5-6H,1-4H3,(H2,15,16,17,20,24) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Slovenia Azimsulfuron (Corrigendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron 26Mar2010 2010 doi:10.2903/j.efsa.2010.1554
+Azimsulfuron 601-676-5 120162-55-2 single chemical entity Component is identical to the substance Azimsulfuron 601-676-5 120162-55-2 N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide Azimsulfuron C13H16N10O5S Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(OC)cc(OC)n3 InChI=1S/C13H16N10O5S/c1-22-11(7(6-14-22)10-18-21-23(2)19-10)29(25,26)20-13(24)17-12-15-8(27-3)5-9(16-12)28-4/h5-6H,1-4H3,(H2,15,16,17,20,24) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Slovenia Azimsulfuron (Corrigendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron 26Mar2010 2010 doi:10.2903/j.efsa.2010.1554
+Azimsulfuron 601-676-5 120162-55-2 single chemical entity Component is identical to the substance Azimsulfuron 601-676-5 120162-55-2 N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide Azimsulfuron C13H16N10O5S Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(OC)cc(OC)n3 InChI=1S/C13H16N10O5S/c1-22-11(7(6-14-22)10-18-21-23(2)19-10)29(25,26)20-13(24)17-12-15-8(27-3)5-9(16-12)28-4/h5-6H,1-4H3,(H2,15,16,17,20,24) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: Sweden - CoRMS: Slovenia Azimsulfuron (Corrigendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron 26Mar2010 2010 doi:10.2903/j.efsa.2010.1554
+Azimsulfuron 601-676-5 120162-55-2 single chemical entity Component is identical to the substance Azimsulfuron 601-676-5 120162-55-2 N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide Azimsulfuron C13H16N10O5S Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(OC)cc(OC)n3 InChI=1S/C13H16N10O5S/c1-22-11(7(6-14-22)10-18-21-23(2)19-10)29(25,26)20-13(24)17-12-15-8(27-3)5-9(16-12)28-4/h5-6H,1-4H3,(H2,15,16,17,20,24) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: Sweden - CoRMS: Slovenia Azimsulfuron (Corrigendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron 26Mar2010 2010 doi:10.2903/j.efsa.2010.1554
+Azimsulfuron 601-676-5 120162-55-2 single chemical entity Component is a metabolite of the substance IN-E6758 phenyl (4,6-dimethoxypyrimidin-2-yl)carbamate Not in list C13H13N3O4 O=C(Oc1ccccc1)Nc2nc(cc(OC)n2)OC InChI=1/C13H13N3O4/c1-18-10-8-11(19-2)15-12(14-10)16-13(17)20-9-6-4-3-5-7-9/h3-8H,1-2H3,(H,14,15,16,17) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Swiss 10 Male/Female intraperitoneal 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Sweden - CoRMS: Slovenia Azimsulfuron (Corrigendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron 26Mar2010 2010 doi:10.2903/j.efsa.2010.1554
+Azimsulfuron 601-676-5 120162-55-2 single chemical entity Component is a metabolite of the substance IN-E6758 phenyl (4,6-dimethoxypyrimidin-2-yl)carbamate Not in list C13H13N3O4 O=C(Oc1ccccc1)Nc2nc(cc(OC)n2)OC InChI=1/C13H13N3O4/c1-18-10-8-11(19-2)15-12(14-10)16-13(17)20-9-6-4-3-5-7-9/h3-8H,1-2H3,(H,14,15,16,17) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Swiss 10 Male/Female intraperitoneal 72.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Sweden - CoRMS: Slovenia Azimsulfuron (Corrigendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron 26Mar2010 2010 doi:10.2903/j.efsa.2010.1554
+Azimsulfuron 601-676-5 120162-55-2 single chemical entity Component is a metabolite of the substance IN-E6758 phenyl (4,6-dimethoxypyrimidin-2-yl)carbamate Not in list C13H13N3O4 O=C(Oc1ccccc1)Nc2nc(cc(OC)n2)OC InChI=1/C13H13N3O4/c1-18-10-8-11(19-2)15-12(14-10)16-13(17)20-9-6-4-3-5-7-9/h3-8H,1-2H3,(H,14,15,16,17) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Swiss 10 Male/Female intraperitoneal 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Sweden - CoRMS: Slovenia Azimsulfuron (Corrigendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron 26Mar2010 2010 doi:10.2903/j.efsa.2010.1554
+Azimsulfuron 601-676-5 120162-55-2 single chemical entity Component is identical to the substance Azimsulfuron 601-676-5 120162-55-2 N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide Azimsulfuron C13H16N10O5S Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(OC)cc(OC)n3 InChI=1S/C13H16N10O5S/c1-22-11(7(6-14-22)10-18-21-23(2)19-10)29(25,26)20-13(24)17-12-15-8(27-3)5-9(16-12)28-4/h5-6H,1-4H3,(H2,15,16,17,20,24) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 72.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity$indirect evidence-systemic toxicity RMS: Sweden - CoRMS: Slovenia Azimsulfuron (Corrigendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron 26Mar2010 2010 doi:10.2903/j.efsa.2010.1554
+Azimsulfuron 601-676-5 120162-55-2 single chemical entity Component is identical to the substance Azimsulfuron 601-676-5 120162-55-2 N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide Azimsulfuron C13H16N10O5S Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(OC)cc(OC)n3 InChI=1S/C13H16N10O5S/c1-22-11(7(6-14-22)10-18-21-23(2)19-10)29(25,26)20-13(24)17-12-15-8(27-3)5-9(16-12)28-4/h5-6H,1-4H3,(H2,15,16,17,20,24) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity$indirect evidence-systemic toxicity RMS: Sweden - CoRMS: Slovenia Azimsulfuron (Corrigendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron 26Mar2010 2010 doi:10.2903/j.efsa.2010.1554
+Azimsulfuron 601-676-5 120162-55-2 single chemical entity Component is identical to the substance Azimsulfuron 601-676-5 120162-55-2 N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide Azimsulfuron C13H16N10O5S Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(OC)cc(OC)n3 InChI=1S/C13H16N10O5S/c1-22-11(7(6-14-22)10-18-21-23(2)19-10)29(25,26)20-13(24)17-12-15-8(27-3)5-9(16-12)28-4/h5-6H,1-4H3,(H2,15,16,17,20,24) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity$indirect evidence-systemic toxicity RMS: Sweden - CoRMS: Slovenia Azimsulfuron (Corrigendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron 26Mar2010 2010 doi:10.2903/j.efsa.2010.1554
+Benfluralin 217-465-2 1861-40-1 single chemical entity Component is identical to the substance Benfluralin 217-465-2 1861-40-1 N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline Benfluralin C13H16F3N3O4 CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benfluralin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin 28Jul2008 2008 doi:10.2903/j.efsa.2008.127r
+Benfluralin 217-465-2 1861-40-1 single chemical entity Component is identical to the substance Benfluralin 217-465-2 1861-40-1 N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline Benfluralin C13H16F3N3O4 CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benfluralin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin 28Jul2008 2008 doi:10.2903/j.efsa.2008.127r
+Benfluralin 217-465-2 1861-40-1 single chemical entity Component is identical to the substance Benfluralin 217-465-2 1861-40-1 N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline Benfluralin C13H16F3N3O4 CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benfluralin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin 28Jul2008 2008 doi:10.2903/j.efsa.2008.127r
+Benfluralin 217-465-2 1861-40-1 single chemical entity Component is identical to the substance Benfluralin 217-465-2 1861-40-1 N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline Benfluralin C13H16F3N3O4 CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Belgium Benfluralin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin 28Jul2008 2008 doi:10.2903/j.efsa.2008.127r
+Benfluralin 217-465-2 1861-40-1 single chemical entity Component is identical to the substance Benfluralin 217-465-2 1861-40-1 N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline Benfluralin C13H16F3N3O4 CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Belgium Benfluralin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin 28Jul2008 2008 doi:10.2903/j.efsa.2008.127r
+Benfluralin 217-465-2 1861-40-1 single chemical entity Component is identical to the substance Benfluralin 217-465-2 1861-40-1 N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline Benfluralin C13H16F3N3O4 CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benfluralin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin 28Jul2008 2008 doi:10.2903/j.efsa.2008.127r
+Benfluralin 217-465-2 1861-40-1 single chemical entity Component is identical to the substance Benfluralin 217-465-2 1861-40-1 N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline Benfluralin C13H16F3N3O4 CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benfluralin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin 28Jul2008 2008 doi:10.2903/j.efsa.2008.127r
+Benfluralin 217-465-2 1861-40-1 single chemical entity Component is identical to the substance Benfluralin 217-465-2 1861-40-1 N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline Benfluralin C13H16F3N3O4 CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benfluralin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin 28Jul2008 2008 doi:10.2903/j.efsa.2008.127r
+Benfluralin 217-465-2 1861-40-1 single chemical entity Component is identical to the substance Benfluralin 217-465-2 1861-40-1 N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline Benfluralin C13H16F3N3O4 CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benfluralin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin 28Jul2008 2008 doi:10.2903/j.efsa.2008.127r
+Benfluralin 217-465-2 1861-40-1 single chemical entity Component is identical to the substance Benfluralin 217-465-2 1861-40-1 N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline Benfluralin C13H16F3N3O4 CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benfluralin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin 28Jul2008 2008 doi:10.2903/j.efsa.2008.127r
+Benfluralin 217-465-2 1861-40-1 single chemical entity Component is identical to the substance Benfluralin 217-465-2 1861-40-1 N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline Benfluralin C13H16F3N3O4 CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benfluralin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin 28Jul2008 2008 doi:10.2903/j.efsa.2008.127r
+Benfluralin 217-465-2 1861-40-1 single chemical entity Component is identical to the substance Benfluralin 217-465-2 1861-40-1 N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline Benfluralin C13H16F3N3O4 CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benfluralin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin 28Jul2008 2008 doi:10.2903/j.efsa.2008.127r
+Benfluralin 217-465-2 1861-40-1 single chemical entity Component is identical to the substance Benfluralin 217-465-2 1861-40-1 N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline Benfluralin C13H16F3N3O4 CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benfluralin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin 28Jul2008 2008 doi:10.2903/j.efsa.2008.127r
+Benfluralin 217-465-2 1861-40-1 single chemical entity Component is identical to the substance Benfluralin 217-465-2 1861-40-1 N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline Benfluralin C13H16F3N3O4 CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Belgium Benfluralin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin 28Jul2008 2008 doi:10.2903/j.efsa.2008.127r
+Benfluralin 217-465-2 1861-40-1 single chemical entity Component is identical to the substance Benfluralin 217-465-2 1861-40-1 N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline Benfluralin C13H16F3N3O4 CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Belgium Benfluralin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin 28Jul2008 2008 doi:10.2903/j.efsa.2008.127r
+Benfluralin 217-465-2 1861-40-1 single chemical entity Component is identical to the substance Benfluralin 217-465-2 1861-40-1 N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline Benfluralin C13H16F3N3O4 CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benfluralin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin 28Jul2008 2008 doi:10.2903/j.efsa.2008.127r
+Benfluralin 217-465-2 1861-40-1 single chemical entity Component is identical to the substance Benfluralin 217-465-2 1861-40-1 N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline Benfluralin C13H16F3N3O4 CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benfluralin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin 28Jul2008 2008 doi:10.2903/j.efsa.2008.127r
+Benfluralin 217-465-2 1861-40-1 single chemical entity Component is identical to the substance Benfluralin 217-465-2 1861-40-1 N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline Benfluralin C13H16F3N3O4 CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benfluralin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin 28Jul2008 2008 doi:10.2903/j.efsa.2008.127r
+Benfluralin 217-465-2 1861-40-1 single chemical entity Component is identical to the substance Benfluralin 217-465-2 1861-40-1 N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline Benfluralin C13H16F3N3O4 CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benfluralin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin 28Jul2008 2008 doi:10.2903/j.efsa.2008.127r
+Benfluralin 217-465-2 1861-40-1 single chemical entity Component is identical to the substance Benfluralin 217-465-2 1861-40-1 N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline Benfluralin C13H16F3N3O4 CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benfluralin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin 28Jul2008 2008 doi:10.2903/j.efsa.2008.127r
+Benfluralin 217-465-2 1861-40-1 single chemical entity Component is identical to the substance Benfluralin 217-465-2 1861-40-1 N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline Benfluralin C13H16F3N3O4 CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benfluralin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin 28Jul2008 2008 doi:10.2903/j.efsa.2008.127r
+Benfluralin 217-465-2 1861-40-1 single chemical entity Component is identical to the substance Benfluralin 217-465-2 1861-40-1 N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline Benfluralin C13H16F3N3O4 CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benfluralin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin 28Jul2008 2008 doi:10.2903/j.efsa.2008.127r
+Benfluralin 217-465-2 1861-40-1 single chemical entity Component is identical to the substance Benfluralin 217-465-2 1861-40-1 N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline Benfluralin C13H16F3N3O4 CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benfluralin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin 28Jul2008 2008 doi:10.2903/j.efsa.2008.127r
+Benfluralin 217-465-2 1861-40-1 single chemical entity Component is identical to the substance Benfluralin 217-465-2 1861-40-1 N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline Benfluralin C13H16F3N3O4 CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benfluralin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin 28Jul2008 2008 doi:10.2903/j.efsa.2008.127r
+Benfuracarb 82560-54-1 single chemical entity Component is identical to the substance Benfuracarb 82560-54-1 ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate Benfuracarb C20H30N2O5S CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Belgium Benfuracarb 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is identical to the substance Benfuracarb 82560-54-1 ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate Benfuracarb C20H30N2O5S CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Belgium Benfuracarb 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is identical to the substance Benfuracarb 82560-54-1 ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate Benfuracarb C20H30N2O5S CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Belgium Benfuracarb 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is identical to the substance Benfuracarb 82560-54-1 ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate Benfuracarb C20H30N2O5S CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Belgium Benfuracarb 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is identical to the substance Benfuracarb 82560-54-1 ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate Benfuracarb C20H30N2O5S CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Belgium Benfuracarb 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is identical to the substance Benfuracarb 82560-54-1 ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate Benfuracarb C20H30N2O5S CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Belgium Benfuracarb 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is identical to the substance Benfuracarb 82560-54-1 ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate Benfuracarb C20H30N2O5S CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: Belgium Benfuracarb 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is identical to the substance Benfuracarb 82560-54-1 ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate Benfuracarb C20H30N2O5S CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: Belgium Benfuracarb 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is identical to the substance Benfuracarb 82560-54-1 ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate Benfuracarb C20H30N2O5S CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Belgium Benfuracarb 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is identical to the substance Benfuracarb 82560-54-1 ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate Benfuracarb C20H30N2O5S CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Belgium Benfuracarb 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is identical to the substance Benfuracarb 82560-54-1 ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate Benfuracarb C20H30N2O5S CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Belgium Benfuracarb 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is identical to the substance Benfuracarb 82560-54-1 ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate Benfuracarb C20H30N2O5S CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Belgium Benfuracarb 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is identical to the substance Benfuracarb 82560-54-1 ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate Benfuracarb C20H30N2O5S CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Belgium Benfuracarb 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is identical to the substance Benfuracarb 82560-54-1 ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate Benfuracarb C20H30N2O5S CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Belgium Benfuracarb 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is identical to the substance Benfuracarb 82560-54-1 ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate Benfuracarb C20H30N2O5S CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: Belgium Benfuracarb 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is identical to the substance Benfuracarb 82560-54-1 ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate Benfuracarb C20H30N2O5S CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Belgium Benfuracarb 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is identical to the substance Benfuracarb 82560-54-1 ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate Benfuracarb C20H30N2O5S CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: Belgium Benfuracarb 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is identical to the substance Benfuracarb 82560-54-1 ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate Benfuracarb C20H30N2O5S CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Belgium Benfuracarb 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is identical to the substance Benfuracarb 82560-54-1 ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate Benfuracarb C20H30N2O5S CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Belgium Benfuracarb 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is identical to the substance Benfuracarb 82560-54-1 ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate Benfuracarb C20H30N2O5S CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Belgium Benfuracarb 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is identical to the substance Benfuracarb 82560-54-1 ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate Benfuracarb C20H30N2O5S CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Belgium Benfuracarb 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is identical to the substance Benfuracarb 82560-54-1 ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate Benfuracarb C20H30N2O5S CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Belgium Benfuracarb 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is identical to the substance Benfuracarb 82560-54-1 ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate Benfuracarb C20H30N2O5S CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Belgium Benfuracarb 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is identical to the substance Benfuracarb 82560-54-1 ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate Benfuracarb C20H30N2O5S CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Belgium Benfuracarb 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is identical to the substance Benfuracarb 82560-54-1 ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate Benfuracarb C20H30N2O5S CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female intraperitoneal 48.0000000000 h yes, historical not applicable Negative indirect evidence-systemic toxicity RMS: Belgium Benfuracarb 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is identical to the substance Benfuracarb 82560-54-1 ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate Benfuracarb C20H30N2O5S CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female intraperitoneal 24.0000000000 h yes, historical not applicable Negative indirect evidence-systemic toxicity RMS: Belgium Benfuracarb 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Bensulfuron-methyl 401-340-6 83055-99-6 single chemical entity Component is identical to the substance Bensulfuron-methyl 401-340-6 83055-99-6 Methyl 2-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoylmethyl]benzoate Bensulfuron-Methyl C16H18N4O7S COC1=CC(=NC(=N1)NC(=O)NS(=O)(=O)CC2=CC=CC=C2C(=O)OC)OC InChI=1S/C16H18N4O7S/c1-25-12-8-13(26-2)18-15(17-12)19-16(22)20-28(23,24)9-10-6-4-5-7-11(10)14(21)27-3/h4-8H,9H2,1-3H3,(H2,17,18,19,20,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Italy Bensulfuron Methyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.178r
+Bensulfuron-methyl 401-340-6 83055-99-6 single chemical entity Component is identical to the substance Bensulfuron-methyl 401-340-6 83055-99-6 Methyl 2-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoylmethyl]benzoate Bensulfuron-Methyl C16H18N4O7S COC1=CC(=NC(=N1)NC(=O)NS(=O)(=O)CC2=CC=CC=C2C(=O)OC)OC InChI=1S/C16H18N4O7S/c1-25-12-8-13(26-2)18-15(17-12)19-16(22)20-28(23,24)9-10-6-4-5-7-11(10)14(21)27-3/h4-8H,9H2,1-3H3,(H2,17,18,19,20,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Italy Bensulfuron Methyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.178r
+Bensulfuron-methyl 401-340-6 83055-99-6 single chemical entity Component is identical to the substance Bensulfuron-methyl 401-340-6 83055-99-6 Methyl 2-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoylmethyl]benzoate Bensulfuron-Methyl C16H18N4O7S COC1=CC(=NC(=N1)NC(=O)NS(=O)(=O)CC2=CC=CC=C2C(=O)OC)OC InChI=1S/C16H18N4O7S/c1-25-12-8-13(26-2)18-15(17-12)19-16(22)20-28(23,24)9-10-6-4-5-7-11(10)14(21)27-3/h4-8H,9H2,1-3H3,(H2,17,18,19,20,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Italy Bensulfuron Methyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.178r
+Bensulfuron-methyl 401-340-6 83055-99-6 single chemical entity Component is identical to the substance Bensulfuron-methyl 401-340-6 83055-99-6 Methyl 2-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoylmethyl]benzoate Bensulfuron-Methyl C16H18N4O7S COC1=CC(=NC(=N1)NC(=O)NS(=O)(=O)CC2=CC=CC=C2C(=O)OC)OC InChI=1S/C16H18N4O7S/c1-25-12-8-13(26-2)18-15(17-12)19-16(22)20-28(23,24)9-10-6-4-5-7-11(10)14(21)27-3/h4-8H,9H2,1-3H3,(H2,17,18,19,20,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Italy Bensulfuron Methyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.178r
+Bensulfuron-methyl 401-340-6 83055-99-6 single chemical entity Component is identical to the substance Bensulfuron-methyl 401-340-6 83055-99-6 Methyl 2-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoylmethyl]benzoate Bensulfuron-Methyl C16H18N4O7S COC1=CC(=NC(=N1)NC(=O)NS(=O)(=O)CC2=CC=CC=C2C(=O)OC)OC InChI=1S/C16H18N4O7S/c1-25-12-8-13(26-2)18-15(17-12)19-16(22)20-28(23,24)9-10-6-4-5-7-11(10)14(21)27-3/h4-8H,9H2,1-3H3,(H2,17,18,19,20,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Italy Bensulfuron Methyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.178r
+Bensulfuron-methyl 401-340-6 83055-99-6 single chemical entity Component is identical to the substance Bensulfuron-methyl 401-340-6 83055-99-6 Methyl 2-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoylmethyl]benzoate Bensulfuron-Methyl C16H18N4O7S COC1=CC(=NC(=N1)NC(=O)NS(=O)(=O)CC2=CC=CC=C2C(=O)OC)OC InChI=1S/C16H18N4O7S/c1-25-12-8-13(26-2)18-15(17-12)19-16(22)20-28(23,24)9-10-6-4-5-7-11(10)14(21)27-3/h4-8H,9H2,1-3H3,(H2,17,18,19,20,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Italy Bensulfuron Methyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.178r
+Bensulfuron-methyl 401-340-6 83055-99-6 single chemical entity Component is identical to the substance Bensulfuron-methyl 401-340-6 83055-99-6 Methyl 2-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoylmethyl]benzoate Bensulfuron-Methyl C16H18N4O7S COC1=CC(=NC(=N1)NC(=O)NS(=O)(=O)CC2=CC=CC=C2C(=O)OC)OC InChI=1S/C16H18N4O7S/c1-25-12-8-13(26-2)18-15(17-12)19-16(22)20-28(23,24)9-10-6-4-5-7-11(10)14(21)27-3/h4-8H,9H2,1-3H3,(H2,17,18,19,20,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Italy Bensulfuron Methyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.178r
+Bensulfuron-methyl 401-340-6 83055-99-6 single chemical entity Component is identical to the substance Bensulfuron-methyl 401-340-6 83055-99-6 Methyl 2-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoylmethyl]benzoate Bensulfuron-Methyl C16H18N4O7S COC1=CC(=NC(=N1)NC(=O)NS(=O)(=O)CC2=CC=CC=C2C(=O)OC)OC InChI=1S/C16H18N4O7S/c1-25-12-8-13(26-2)18-15(17-12)19-16(22)20-28(23,24)9-10-6-4-5-7-11(10)14(21)27-3/h4-8H,9H2,1-3H3,(H2,17,18,19,20,22) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes without Negative RMS: Italy Bensulfuron Methyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.178r
+Bensulfuron-methyl 401-340-6 83055-99-6 single chemical entity Component is identical to the substance Bensulfuron-methyl 401-340-6 83055-99-6 Methyl 2-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoylmethyl]benzoate Bensulfuron-Methyl C16H18N4O7S COC1=CC(=NC(=N1)NC(=O)NS(=O)(=O)CC2=CC=CC=C2C(=O)OC)OC InChI=1S/C16H18N4O7S/c1-25-12-8-13(26-2)18-15(17-12)19-16(22)20-28(23,24)9-10-6-4-5-7-11(10)14(21)27-3/h4-8H,9H2,1-3H3,(H2,17,18,19,20,22) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes with Negative RMS: Italy Bensulfuron Methyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.178r
+Bensulfuron-methyl 401-340-6 83055-99-6 single chemical entity Component is identical to the substance Bensulfuron-methyl 401-340-6 83055-99-6 Methyl 2-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoylmethyl]benzoate Bensulfuron-Methyl C16H18N4O7S COC1=CC(=NC(=N1)NC(=O)NS(=O)(=O)CC2=CC=CC=C2C(=O)OC)OC InChI=1S/C16H18N4O7S/c1-25-12-8-13(26-2)18-15(17-12)19-16(22)20-28(23,24)9-10-6-4-5-7-11(10)14(21)27-3/h4-8H,9H2,1-3H3,(H2,17,18,19,20,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Italy Bensulfuron Methyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.178r
+Bensulfuron-methyl 401-340-6 83055-99-6 single chemical entity Component is identical to the substance Bensulfuron-methyl 401-340-6 83055-99-6 Methyl 2-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoylmethyl]benzoate Bensulfuron-Methyl C16H18N4O7S COC1=CC(=NC(=N1)NC(=O)NS(=O)(=O)CC2=CC=CC=C2C(=O)OC)OC InChI=1S/C16H18N4O7S/c1-25-12-8-13(26-2)18-15(17-12)19-16(22)20-28(23,24)9-10-6-4-5-7-11(10)14(21)27-3/h4-8H,9H2,1-3H3,(H2,17,18,19,20,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Italy Bensulfuron Methyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.178r
+Bensulfuron-methyl 401-340-6 83055-99-6 single chemical entity Component is identical to the substance Bensulfuron-methyl 401-340-6 83055-99-6 Methyl 2-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoylmethyl]benzoate Bensulfuron-Methyl C16H18N4O7S COC1=CC(=NC(=N1)NC(=O)NS(=O)(=O)CC2=CC=CC=C2C(=O)OC)OC InChI=1S/C16H18N4O7S/c1-25-12-8-13(26-2)18-15(17-12)19-16(22)20-28(23,24)9-10-6-4-5-7-11(10)14(21)27-3/h4-8H,9H2,1-3H3,(H2,17,18,19,20,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Italy Bensulfuron Methyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.178r
+Bensulfuron-methyl 401-340-6 83055-99-6 single chemical entity Component is identical to the substance Bensulfuron-methyl 401-340-6 83055-99-6 Methyl 2-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoylmethyl]benzoate Bensulfuron-Methyl C16H18N4O7S COC1=CC(=NC(=N1)NC(=O)NS(=O)(=O)CC2=CC=CC=C2C(=O)OC)OC InChI=1S/C16H18N4O7S/c1-25-12-8-13(26-2)18-15(17-12)19-16(22)20-28(23,24)9-10-6-4-5-7-11(10)14(21)27-3/h4-8H,9H2,1-3H3,(H2,17,18,19,20,22) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro According to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Italy Bensulfuron Methyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.178r
+Bensulfuron-methyl 401-340-6 83055-99-6 single chemical entity Component is identical to the substance Bensulfuron-methyl 401-340-6 83055-99-6 Methyl 2-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoylmethyl]benzoate Bensulfuron-Methyl C16H18N4O7S COC1=CC(=NC(=N1)NC(=O)NS(=O)(=O)CC2=CC=CC=C2C(=O)OC)OC InChI=1S/C16H18N4O7S/c1-25-12-8-13(26-2)18-15(17-12)19-16(22)20-28(23,24)9-10-6-4-5-7-11(10)14(21)27-3/h4-8H,9H2,1-3H3,(H2,17,18,19,20,22) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro According to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Positive RMS: Italy Bensulfuron Methyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.178r
+Bensulfuron-methyl 401-340-6 83055-99-6 single chemical entity Component is identical to the substance Bensulfuron-methyl 401-340-6 83055-99-6 Methyl 2-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoylmethyl]benzoate Bensulfuron-Methyl C16H18N4O7S COC1=CC(=NC(=N1)NC(=O)NS(=O)(=O)CC2=CC=CC=C2C(=O)OC)OC InChI=1S/C16H18N4O7S/c1-25-12-8-13(26-2)18-15(17-12)19-16(22)20-28(23,24)9-10-6-4-5-7-11(10)14(21)27-3/h4-8H,9H2,1-3H3,(H2,17,18,19,20,22) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Sprague-Dawley 30 Male/Female oral: gavage 6.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Italy Bensulfuron Methyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.178r
+Bensulfuron-methyl 401-340-6 83055-99-6 single chemical entity Component is identical to the substance Bensulfuron-methyl 401-340-6 83055-99-6 Methyl 2-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoylmethyl]benzoate Bensulfuron-Methyl C16H18N4O7S COC1=CC(=NC(=N1)NC(=O)NS(=O)(=O)CC2=CC=CC=C2C(=O)OC)OC InChI=1S/C16H18N4O7S/c1-25-12-8-13(26-2)18-15(17-12)19-16(22)20-28(23,24)9-10-6-4-5-7-11(10)14(21)27-3/h4-8H,9H2,1-3H3,(H2,17,18,19,20,22) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Sprague-Dawley 30 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Italy Bensulfuron Methyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.178r
+Bensulfuron-methyl 401-340-6 83055-99-6 single chemical entity Component is identical to the substance Bensulfuron-methyl 401-340-6 83055-99-6 Methyl 2-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoylmethyl]benzoate Bensulfuron-Methyl C16H18N4O7S COC1=CC(=NC(=N1)NC(=O)NS(=O)(=O)CC2=CC=CC=C2C(=O)OC)OC InChI=1S/C16H18N4O7S/c1-25-12-8-13(26-2)18-15(17-12)19-16(22)20-28(23,24)9-10-6-4-5-7-11(10)14(21)27-3/h4-8H,9H2,1-3H3,(H2,17,18,19,20,22) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Sprague-Dawley 30 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Italy Bensulfuron Methyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.178r
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is part of a group assessment bentazone sodium 256-735-4 50723-80-3 sodium;2,2-dioxo-3-propan-2-yl-2$l^{6},1,3-benzothiadiazin-1-id-4-one Not in list C10H11N2NaO3S CC(C)N1C(=O)C2=CC=CC=C2[N-]S1(=O)=O.[Na+] InChI=1S/C10H12N2O3S.Na/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15;/h3-7H,1-2H3,(H,11,13);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is part of a group assessment bentazone sodium 256-735-4 50723-80-3 sodium;2,2-dioxo-3-propan-2-yl-2$l^{6},1,3-benzothiadiazin-1-id-4-one Not in list C10H11N2NaO3S CC(C)N1C(=O)C2=CC=CC=C2[N-]S1(=O)=O.[Na+] InChI=1S/C10H12N2O3S.Na/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15;/h3-7H,1-2H3,(H,11,13);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is part of a group assessment bentazone sodium 256-735-4 50723-80-3 sodium;2,2-dioxo-3-propan-2-yl-2$l^{6},1,3-benzothiadiazin-1-id-4-one Not in list C10H11N2NaO3S CC(C)N1C(=O)C2=CC=CC=C2[N-]S1(=O)=O.[Na+] InChI=1S/C10H12N2O3S.Na/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15;/h3-7H,1-2H3,(H,11,13);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is part of a group assessment bentazone sodium 256-735-4 50723-80-3 sodium;2,2-dioxo-3-propan-2-yl-2$l^{6},1,3-benzothiadiazin-1-id-4-one Not in list C10H11N2NaO3S CC(C)N1C(=O)C2=CC=CC=C2[N-]S1(=O)=O.[Na+] InChI=1S/C10H12N2O3S.Na/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15;/h3-7H,1-2H3,(H,11,13);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is part of a group assessment bentazone sodium 256-735-4 50723-80-3 sodium;2,2-dioxo-3-propan-2-yl-2$l^{6},1,3-benzothiadiazin-1-id-4-one Not in list C10H11N2NaO3S CC(C)N1C(=O)C2=CC=CC=C2[N-]S1(=O)=O.[Na+] InChI=1S/C10H12N2O3S.Na/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15;/h3-7H,1-2H3,(H,11,13);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is part of a group assessment bentazone sodium 256-735-4 50723-80-3 sodium;2,2-dioxo-3-propan-2-yl-2$l^{6},1,3-benzothiadiazin-1-id-4-one Not in list C10H11N2NaO3S CC(C)N1C(=O)C2=CC=CC=C2[N-]S1(=O)=O.[Na+] InChI=1S/C10H12N2O3S.Na/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15;/h3-7H,1-2H3,(H,11,13);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is part of a group assessment bentazone sodium 256-735-4 50723-80-3 sodium;2,2-dioxo-3-propan-2-yl-2$l^{6},1,3-benzothiadiazin-1-id-4-one Not in list C10H11N2NaO3S CC(C)N1C(=O)C2=CC=CC=C2[N-]S1(=O)=O.[Na+] InChI=1S/C10H12N2O3S.Na/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15;/h3-7H,1-2H3,(H,11,13);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is part of a group assessment bentazone sodium 256-735-4 50723-80-3 sodium;2,2-dioxo-3-propan-2-yl-2$l^{6},1,3-benzothiadiazin-1-id-4-one Not in list C10H11N2NaO3S CC(C)N1C(=O)C2=CC=CC=C2[N-]S1(=O)=O.[Na+] InChI=1S/C10H12N2O3S.Na/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15;/h3-7H,1-2H3,(H,11,13);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is part of a group assessment bentazone sodium 256-735-4 50723-80-3 sodium;2,2-dioxo-3-propan-2-yl-2$l^{6},1,3-benzothiadiazin-1-id-4-one Not in list C10H11N2NaO3S CC(C)N1C(=O)C2=CC=CC=C2[N-]S1(=O)=O.[Na+] InChI=1S/C10H12N2O3S.Na/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15;/h3-7H,1-2H3,(H,11,13);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is part of a group assessment bentazone sodium 256-735-4 50723-80-3 sodium;2,2-dioxo-3-propan-2-yl-2$l^{6},1,3-benzothiadiazin-1-id-4-one Not in list C10H11N2NaO3S CC(C)N1C(=O)C2=CC=CC=C2[N-]S1(=O)=O.[Na+] InChI=1S/C10H12N2O3S.Na/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15;/h3-7H,1-2H3,(H,11,13);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is part of a group assessment bentazone sodium 256-735-4 50723-80-3 sodium;2,2-dioxo-3-propan-2-yl-2$l^{6},1,3-benzothiadiazin-1-id-4-one Not in list C10H11N2NaO3S CC(C)N1C(=O)C2=CC=CC=C2[N-]S1(=O)=O.[Na+] InChI=1S/C10H12N2O3S.Na/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15;/h3-7H,1-2H3,(H,11,13);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is part of a group assessment bentazone sodium 256-735-4 50723-80-3 sodium;2,2-dioxo-3-propan-2-yl-2$l^{6},1,3-benzothiadiazin-1-id-4-one Not in list C10H11N2NaO3S CC(C)N1C(=O)C2=CC=CC=C2[N-]S1(=O)=O.[Na+] InChI=1S/C10H12N2O3S.Na/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15;/h3-7H,1-2H3,(H,11,13);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is part of a group assessment bentazone sodium 256-735-4 50723-80-3 sodium;2,2-dioxo-3-propan-2-yl-2$l^{6},1,3-benzothiadiazin-1-id-4-one Not in list C10H11N2NaO3S CC(C)N1C(=O)C2=CC=CC=C2[N-]S1(=O)=O.[Na+] InChI=1S/C10H12N2O3S.Na/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15;/h3-7H,1-2H3,(H,11,13);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is part of a group assessment bentazone sodium 256-735-4 50723-80-3 sodium;2,2-dioxo-3-propan-2-yl-2$l^{6},1,3-benzothiadiazin-1-id-4-one Not in list C10H11N2NaO3S CC(C)N1C(=O)C2=CC=CC=C2[N-]S1(=O)=O.[Na+] InChI=1S/C10H12N2O3S.Na/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15;/h3-7H,1-2H3,(H,11,13);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is part of a group assessment bentazone sodium 256-735-4 50723-80-3 sodium;2,2-dioxo-3-propan-2-yl-2$l^{6},1,3-benzothiadiazin-1-id-4-one Not in list C10H11N2NaO3S CC(C)N1C(=O)C2=CC=CC=C2[N-]S1(=O)=O.[Na+] InChI=1S/C10H12N2O3S.Na/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15;/h3-7H,1-2H3,(H,11,13);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is part of a group assessment bentazone sodium 256-735-4 50723-80-3 sodium;2,2-dioxo-3-propan-2-yl-2$l^{6},1,3-benzothiadiazin-1-id-4-one Not in list C10H11N2NaO3S CC(C)N1C(=O)C2=CC=CC=C2[N-]S1(=O)=O.[Na+] InChI=1S/C10H12N2O3S.Na/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15;/h3-7H,1-2H3,(H,11,13);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is part of a group assessment bentazone sodium 256-735-4 50723-80-3 sodium;2,2-dioxo-3-propan-2-yl-2$l^{6},1,3-benzothiadiazin-1-id-4-one Not in list C10H11N2NaO3S CC(C)N1C(=O)C2=CC=CC=C2[N-]S1(=O)=O.[Na+] InChI=1S/C10H12N2O3S.Na/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15;/h3-7H,1-2H3,(H,11,13);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is part of a group assessment bentazone sodium 256-735-4 50723-80-3 sodium;2,2-dioxo-3-propan-2-yl-2$l^{6},1,3-benzothiadiazin-1-id-4-one Not in list C10H11N2NaO3S CC(C)N1C(=O)C2=CC=CC=C2[N-]S1(=O)=O.[Na+] InChI=1S/C10H12N2O3S.Na/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15;/h3-7H,1-2H3,(H,11,13);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is part of a group assessment bentazone sodium 256-735-4 50723-80-3 sodium;2,2-dioxo-3-propan-2-yl-2$l^{6},1,3-benzothiadiazin-1-id-4-one Not in list C10H11N2NaO3S CC(C)N1C(=O)C2=CC=CC=C2[N-]S1(=O)=O.[Na+] InChI=1S/C10H12N2O3S.Na/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15;/h3-7H,1-2H3,(H,11,13);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is part of a group assessment bentazone sodium 256-735-4 50723-80-3 sodium;2,2-dioxo-3-propan-2-yl-2$l^{6},1,3-benzothiadiazin-1-id-4-one Not in list C10H11N2NaO3S CC(C)N1C(=O)C2=CC=CC=C2[N-]S1(=O)=O.[Na+] InChI=1S/C10H12N2O3S.Na/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15;/h3-7H,1-2H3,(H,11,13);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation other in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) ICR 6 Male oral: gavage 3.0000000000 h yes not applicable Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair SOS/umu test in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) Not reported Not reported no data with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair SOS/umu test in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) Not reported Not reported no data without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent no treatment without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent no treatment with Ambiguous RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is part of a group assessment bentazone sodium 256-735-4 50723-80-3 sodium;2,2-dioxo-3-propan-2-yl-2$l^{6},1,3-benzothiadiazin-1-id-4-one Not in list C10H11N2NaO3S CC(C)N1C(=O)C2=CC=CC=C2[N-]S1(=O)=O.[Na+] InChI=1S/C10H12N2O3S.Na/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15;/h3-7H,1-2H3,(H,11,13);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is part of a group assessment bentazone sodium 256-735-4 50723-80-3 sodium;2,2-dioxo-3-propan-2-yl-2$l^{6},1,3-benzothiadiazin-1-id-4-one Not in list C10H11N2NaO3S CC(C)N1C(=O)C2=CC=CC=C2[N-]S1(=O)=O.[Na+] InChI=1S/C10H12N2O3S.Na/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15;/h3-7H,1-2H3,(H,11,13);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is part of a group assessment bentazone sodium 256-735-4 50723-80-3 sodium;2,2-dioxo-3-propan-2-yl-2$l^{6},1,3-benzothiadiazin-1-id-4-one Not in list C10H11N2NaO3S CC(C)N1C(=O)C2=CC=CC=C2[N-]S1(=O)=O.[Na+] InChI=1S/C10H12N2O3S.Na/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15;/h3-7H,1-2H3,(H,11,13);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Negative no information RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is part of a group assessment bentazone sodium 256-735-4 50723-80-3 sodium;2,2-dioxo-3-propan-2-yl-2$l^{6},1,3-benzothiadiazin-1-id-4-one Not in list C10H11N2NaO3S CC(C)N1C(=O)C2=CC=CC=C2[N-]S1(=O)=O.[Na+] InChI=1S/C10H12N2O3S.Na/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15;/h3-7H,1-2H3,(H,11,13);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative no information RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Positive RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Ambiguous RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is part of a group assessment bentazone sodium 256-735-4 50723-80-3 sodium;2,2-dioxo-3-propan-2-yl-2$l^{6},1,3-benzothiadiazin-1-id-4-one Not in list C10H11N2NaO3S CC(C)N1C(=O)C2=CC=CC=C2[N-]S1(=O)=O.[Na+] InChI=1S/C10H12N2O3S.Na/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15;/h3-7H,1-2H3,(H,11,13);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes with Positive RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is part of a group assessment bentazone sodium 256-735-4 50723-80-3 sodium;2,2-dioxo-3-propan-2-yl-2$l^{6},1,3-benzothiadiazin-1-id-4-one Not in list C10H11N2NaO3S CC(C)N1C(=O)C2=CC=CC=C2[N-]S1(=O)=O.[Na+] InChI=1S/C10H12N2O3S.Na/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15;/h3-7H,1-2H3,(H,11,13);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes without Positive RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 10 Male/Female oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 10 Male/Female oral: unspecified 16.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 10 Male/Female oral: unspecified 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is part of a group assessment bentazone sodium 256-735-4 50723-80-3 sodium;2,2-dioxo-3-propan-2-yl-2$l^{6},1,3-benzothiadiazin-1-id-4-one Not in list C10H11N2NaO3S CC(C)N1C(=O)C2=CC=CC=C2[N-]S1(=O)=O.[Na+] InChI=1S/C10H12N2O3S.Na/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15;/h3-7H,1-2H3,(H,11,13);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female oral: unspecified 24.0000000000 h yes not applicable Negative indirect evidence-systemic toxicity RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is part of a group assessment bentazone sodium 256-735-4 50723-80-3 sodium;2,2-dioxo-3-propan-2-yl-2$l^{6},1,3-benzothiadiazin-1-id-4-one Not in list C10H11N2NaO3S CC(C)N1C(=O)C2=CC=CC=C2[N-]S1(=O)=O.[Na+] InChI=1S/C10H12N2O3S.Na/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15;/h3-7H,1-2H3,(H,11,13);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female oral: unspecified 48.0000000000 h yes not applicable Negative indirect evidence-systemic toxicity RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable Rat (as animal) Wistar Male oral: gavage 24.0000000000 h yes not applicable Negative no evidence RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Wistar Male oral: gavage 24.0000000000 h yes not applicable Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is part of a group assessment bentazone sodium 256-735-4 50723-80-3 sodium;2,2-dioxo-3-propan-2-yl-2$l^{6},1,3-benzothiadiazin-1-id-4-one Not in list C10H11N2NaO3S CC(C)N1C(=O)C2=CC=CC=C2[N-]S1(=O)=O.[Na+] InChI=1S/C10H12N2O3S.Na/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15;/h3-7H,1-2H3,(H,11,13);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Wistar 4 Male Not reported yes, concurrent vehicle not applicable Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration other in vivo No guideline available Not reported Not applicable Acceptable Drosophila melanogaster (as animal) Not reported Male/Female oral: feed yes not applicable Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is a metabolite of the substance 8-hydroxy-3-isopropyl-1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide 611-967-9 60374-43-8 8-hydroxy-2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O4S CC(C)N1C(=O)C2=C(C(=CC=C2)O)NS1(=O)=O InChI=1S/C10H12N2O4S/c1-6(2)12-10(14)7-4-3-5-8(13)9(7)11-17(12,15)16/h3-6,11,13H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is a metabolite of the substance 8-hydroxy-3-isopropyl-1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide 611-967-9 60374-43-8 8-hydroxy-2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O4S CC(C)N1C(=O)C2=C(C(=CC=C2)O)NS1(=O)=O InChI=1S/C10H12N2O4S/c1-6(2)12-10(14)7-4-3-5-8(13)9(7)11-17(12,15)16/h3-6,11,13H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is a metabolite of the substance 8-hydroxy-3-isopropyl-1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide 611-967-9 60374-43-8 8-hydroxy-2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O4S CC(C)N1C(=O)C2=C(C(=CC=C2)O)NS1(=O)=O InChI=1S/C10H12N2O4S/c1-6(2)12-10(14)7-4-3-5-8(13)9(7)11-17(12,15)16/h3-6,11,13H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is a metabolite of the substance 8-hydroxy-3-isopropyl-1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide 611-967-9 60374-43-8 8-hydroxy-2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O4S CC(C)N1C(=O)C2=C(C(=CC=C2)O)NS1(=O)=O InChI=1S/C10H12N2O4S/c1-6(2)12-10(14)7-4-3-5-8(13)9(7)11-17(12,15)16/h3-6,11,13H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is a metabolite of the substance 8-hydroxy-3-isopropyl-1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide 611-967-9 60374-43-8 8-hydroxy-2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O4S CC(C)N1C(=O)C2=C(C(=CC=C2)O)NS1(=O)=O InChI=1S/C10H12N2O4S/c1-6(2)12-10(14)7-4-3-5-8(13)9(7)11-17(12,15)16/h3-6,11,13H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is a metabolite of the substance 8-hydroxy-3-isopropyl-1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide 611-967-9 60374-43-8 8-hydroxy-2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O4S CC(C)N1C(=O)C2=C(C(=CC=C2)O)NS1(=O)=O InChI=1S/C10H12N2O4S/c1-6(2)12-10(14)7-4-3-5-8(13)9(7)11-17(12,15)16/h3-6,11,13H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is a metabolite of the substance 8-hydroxy-3-isopropyl-1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide 611-967-9 60374-43-8 8-hydroxy-2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O4S CC(C)N1C(=O)C2=C(C(=CC=C2)O)NS1(=O)=O InChI=1S/C10H12N2O4S/c1-6(2)12-10(14)7-4-3-5-8(13)9(7)11-17(12,15)16/h3-6,11,13H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is a metabolite of the substance 8-hydroxy-3-isopropyl-1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide 611-967-9 60374-43-8 8-hydroxy-2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O4S CC(C)N1C(=O)C2=C(C(=CC=C2)O)NS1(=O)=O InChI=1S/C10H12N2O4S/c1-6(2)12-10(14)7-4-3-5-8(13)9(7)11-17(12,15)16/h3-6,11,13H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is a metabolite of the substance 8-hydroxy-3-isopropyl-1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide 611-967-9 60374-43-8 8-hydroxy-2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O4S CC(C)N1C(=O)C2=C(C(=CC=C2)O)NS1(=O)=O InChI=1S/C10H12N2O4S/c1-6(2)12-10(14)7-4-3-5-8(13)9(7)11-17(12,15)16/h3-6,11,13H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is a metabolite of the substance 8-hydroxy-3-isopropyl-1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide 611-967-9 60374-43-8 8-hydroxy-2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O4S CC(C)N1C(=O)C2=C(C(=CC=C2)O)NS1(=O)=O InChI=1S/C10H12N2O4S/c1-6(2)12-10(14)7-4-3-5-8(13)9(7)11-17(12,15)16/h3-6,11,13H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is a metabolite of the substance 8-hydroxy-3-isopropyl-1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide 611-967-9 60374-43-8 8-hydroxy-2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O4S CC(C)N1C(=O)C2=C(C(=CC=C2)O)NS1(=O)=O InChI=1S/C10H12N2O4S/c1-6(2)12-10(14)7-4-3-5-8(13)9(7)11-17(12,15)16/h3-6,11,13H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is a metabolite of the substance 8-hydroxy-3-isopropyl-1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide 611-967-9 60374-43-8 8-hydroxy-2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O4S CC(C)N1C(=O)C2=C(C(=CC=C2)O)NS1(=O)=O InChI=1S/C10H12N2O4S/c1-6(2)12-10(14)7-4-3-5-8(13)9(7)11-17(12,15)16/h3-6,11,13H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is a metabolite of the substance 8-hydroxy-3-isopropyl-1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide 611-967-9 60374-43-8 8-hydroxy-2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O4S CC(C)N1C(=O)C2=C(C(=CC=C2)O)NS1(=O)=O InChI=1S/C10H12N2O4S/c1-6(2)12-10(14)7-4-3-5-8(13)9(7)11-17(12,15)16/h3-6,11,13H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is a metabolite of the substance 8-hydroxy-3-isopropyl-1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide 611-967-9 60374-43-8 8-hydroxy-2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O4S CC(C)N1C(=O)C2=C(C(=CC=C2)O)NS1(=O)=O InChI=1S/C10H12N2O4S/c1-6(2)12-10(14)7-4-3-5-8(13)9(7)11-17(12,15)16/h3-6,11,13H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is a metabolite of the substance 8-hydroxy-3-isopropyl-1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide 611-967-9 60374-43-8 8-hydroxy-2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O4S CC(C)N1C(=O)C2=C(C(=CC=C2)O)NS1(=O)=O InChI=1S/C10H12N2O4S/c1-6(2)12-10(14)7-4-3-5-8(13)9(7)11-17(12,15)16/h3-6,11,13H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is a metabolite of the substance 8-hydroxy-3-isopropyl-1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide 611-967-9 60374-43-8 8-hydroxy-2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O4S CC(C)N1C(=O)C2=C(C(=CC=C2)O)NS1(=O)=O InChI=1S/C10H12N2O4S/c1-6(2)12-10(14)7-4-3-5-8(13)9(7)11-17(12,15)16/h3-6,11,13H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is a metabolite of the substance 8-hydroxy-3-isopropyl-1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide 611-967-9 60374-43-8 8-hydroxy-2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O4S CC(C)N1C(=O)C2=C(C(=CC=C2)O)NS1(=O)=O InChI=1S/C10H12N2O4S/c1-6(2)12-10(14)7-4-3-5-8(13)9(7)11-17(12,15)16/h3-6,11,13H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is a metabolite of the substance 8-hydroxy-3-isopropyl-1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide 611-967-9 60374-43-8 8-hydroxy-2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O4S CC(C)N1C(=O)C2=C(C(=CC=C2)O)NS1(=O)=O InChI=1S/C10H12N2O4S/c1-6(2)12-10(14)7-4-3-5-8(13)9(7)11-17(12,15)16/h3-6,11,13H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is a metabolite of the substance 8-hydroxy-3-isopropyl-1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide 611-967-9 60374-43-8 8-hydroxy-2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O4S CC(C)N1C(=O)C2=C(C(=CC=C2)O)NS1(=O)=O InChI=1S/C10H12N2O4S/c1-6(2)12-10(14)7-4-3-5-8(13)9(7)11-17(12,15)16/h3-6,11,13H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is a metabolite of the substance 8-hydroxy-3-isopropyl-1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide 611-967-9 60374-43-8 8-hydroxy-2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O4S CC(C)N1C(=O)C2=C(C(=CC=C2)O)NS1(=O)=O InChI=1S/C10H12N2O4S/c1-6(2)12-10(14)7-4-3-5-8(13)9(7)11-17(12,15)16/h3-6,11,13H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is a metabolite of the substance 8-hydroxy-3-isopropyl-1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide 611-967-9 60374-43-8 8-hydroxy-2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O4S CC(C)N1C(=O)C2=C(C(=CC=C2)O)NS1(=O)=O InChI=1S/C10H12N2O4S/c1-6(2)12-10(14)7-4-3-5-8(13)9(7)11-17(12,15)16/h3-6,11,13H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is a metabolite of the substance 8-hydroxy-3-isopropyl-1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide 611-967-9 60374-43-8 8-hydroxy-2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O4S CC(C)N1C(=O)C2=C(C(=CC=C2)O)NS1(=O)=O InChI=1S/C10H12N2O4S/c1-6(2)12-10(14)7-4-3-5-8(13)9(7)11-17(12,15)16/h3-6,11,13H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is a metabolite of the substance 8-hydroxy-3-isopropyl-1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide 611-967-9 60374-43-8 8-hydroxy-2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O4S CC(C)N1C(=O)C2=C(C(=CC=C2)O)NS1(=O)=O InChI=1S/C10H12N2O4S/c1-6(2)12-10(14)7-4-3-5-8(13)9(7)11-17(12,15)16/h3-6,11,13H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is a metabolite of the substance 8-hydroxy-3-isopropyl-1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide 611-967-9 60374-43-8 8-hydroxy-2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O4S CC(C)N1C(=O)C2=C(C(=CC=C2)O)NS1(=O)=O InChI=1S/C10H12N2O4S/c1-6(2)12-10(14)7-4-3-5-8(13)9(7)11-17(12,15)16/h3-6,11,13H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is a metabolite of the substance 8-hydroxy-3-isopropyl-1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide 611-967-9 60374-43-8 8-hydroxy-2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O4S CC(C)N1C(=O)C2=C(C(=CC=C2)O)NS1(=O)=O InChI=1S/C10H12N2O4S/c1-6(2)12-10(14)7-4-3-5-8(13)9(7)11-17(12,15)16/h3-6,11,13H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is a metabolite of the substance 8-hydroxy-3-isopropyl-1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide 611-967-9 60374-43-8 8-hydroxy-2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O4S CC(C)N1C(=O)C2=C(C(=CC=C2)O)NS1(=O)=O InChI=1S/C10H12N2O4S/c1-6(2)12-10(14)7-4-3-5-8(13)9(7)11-17(12,15)16/h3-6,11,13H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is a metabolite of the substance 8-hydroxy-3-isopropyl-1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide 611-967-9 60374-43-8 8-hydroxy-2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O4S CC(C)N1C(=O)C2=C(C(=CC=C2)O)NS1(=O)=O InChI=1S/C10H12N2O4S/c1-6(2)12-10(14)7-4-3-5-8(13)9(7)11-17(12,15)16/h3-6,11,13H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is a metabolite of the substance 8-hydroxy-3-isopropyl-1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide 611-967-9 60374-43-8 8-hydroxy-2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O4S CC(C)N1C(=O)C2=C(C(=CC=C2)O)NS1(=O)=O InChI=1S/C10H12N2O4S/c1-6(2)12-10(14)7-4-3-5-8(13)9(7)11-17(12,15)16/h3-6,11,13H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female oral: unspecified 16.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Bentazone 246-585-8 25057-89-0 single chemical entity Component is identical to the substance Bentazone 246-585-8 25057-89-0 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one Not in list C10H12N2O3S CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female oral: unspecified 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: The Netherlands Bentazone (RAR) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone 20Apr2015 2015 doi: 10.2903/j.efsa.2015.4077
+Beta-Cypermethrin 265-898-0 65731-84-2 single chemical entity Component is identical to the substance Beta-Cypermethrin 265-898-0 65731-84-2 A reaction mixture comprising two enantiomeric pairs in ratio ca. 2:3 of (R)-alpha-cyano-3-phenoxybenzyl (1S)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate with (R)-alpha-cyano-3-phenoxybenzyl (1S)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate Beta-cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Beta-Cypermethrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance beta-cypermethrin 20Jun2014 2014 doi:10.2903/j.efsa.2014.3717
+Beta-Cypermethrin 265-898-0 65731-84-2 single chemical entity Component is identical to the substance Beta-Cypermethrin 265-898-0 65731-84-2 A reaction mixture comprising two enantiomeric pairs in ratio ca. 2:3 of (R)-alpha-cyano-3-phenoxybenzyl (1S)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate with (R)-alpha-cyano-3-phenoxybenzyl (1S)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate Beta-cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Beta-Cypermethrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance beta-cypermethrin 20Jun2014 2014 doi:10.2903/j.efsa.2014.3717
+Beta-Cypermethrin 265-898-0 65731-84-2 single chemical entity Component is identical to the substance Beta-Cypermethrin 265-898-0 65731-84-2 A reaction mixture comprising two enantiomeric pairs in ratio ca. 2:3 of (R)-alpha-cyano-3-phenoxybenzyl (1S)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate with (R)-alpha-cyano-3-phenoxybenzyl (1S)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate Beta-cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Beta-Cypermethrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance beta-cypermethrin 20Jun2014 2014 doi:10.2903/j.efsa.2014.3717
+Beta-Cypermethrin 265-898-0 65731-84-2 single chemical entity Component is identical to the substance Beta-Cypermethrin 265-898-0 65731-84-2 A reaction mixture comprising two enantiomeric pairs in ratio ca. 2:3 of (R)-alpha-cyano-3-phenoxybenzyl (1S)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate with (R)-alpha-cyano-3-phenoxybenzyl (1S)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate Beta-cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Beta-Cypermethrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance beta-cypermethrin 20Jun2014 2014 doi:10.2903/j.efsa.2014.3717
+Beta-Cypermethrin 265-898-0 65731-84-2 single chemical entity Component is identical to the substance Beta-Cypermethrin 265-898-0 65731-84-2 A reaction mixture comprising two enantiomeric pairs in ratio ca. 2:3 of (R)-alpha-cyano-3-phenoxybenzyl (1S)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate with (R)-alpha-cyano-3-phenoxybenzyl (1S)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate Beta-cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Beta-Cypermethrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance beta-cypermethrin 20Jun2014 2014 doi:10.2903/j.efsa.2014.3717
+Beta-Cypermethrin 265-898-0 65731-84-2 single chemical entity Component is identical to the substance Beta-Cypermethrin 265-898-0 65731-84-2 A reaction mixture comprising two enantiomeric pairs in ratio ca. 2:3 of (R)-alpha-cyano-3-phenoxybenzyl (1S)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate with (R)-alpha-cyano-3-phenoxybenzyl (1S)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate Beta-cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Beta-Cypermethrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance beta-cypermethrin 20Jun2014 2014 doi:10.2903/j.efsa.2014.3717
+Beta-Cypermethrin 265-898-0 65731-84-2 single chemical entity Component is identical to the substance Beta-Cypermethrin 265-898-0 65731-84-2 A reaction mixture comprising two enantiomeric pairs in ratio ca. 2:3 of (R)-alpha-cyano-3-phenoxybenzyl (1S)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate with (R)-alpha-cyano-3-phenoxybenzyl (1S)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate Beta-cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Beta-Cypermethrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance beta-cypermethrin 20Jun2014 2014 doi:10.2903/j.efsa.2014.3717
+Beta-Cypermethrin 265-898-0 65731-84-2 single chemical entity Component is identical to the substance Beta-Cypermethrin 265-898-0 65731-84-2 A reaction mixture comprising two enantiomeric pairs in ratio ca. 2:3 of (R)-alpha-cyano-3-phenoxybenzyl (1S)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate with (R)-alpha-cyano-3-phenoxybenzyl (1S)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate Beta-cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Beta-Cypermethrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance beta-cypermethrin 20Jun2014 2014 doi:10.2903/j.efsa.2014.3717
+Beta-Cypermethrin 265-898-0 65731-84-2 single chemical entity Component is identical to the substance Beta-Cypermethrin 265-898-0 65731-84-2 A reaction mixture comprising two enantiomeric pairs in ratio ca. 2:3 of (R)-alpha-cyano-3-phenoxybenzyl (1S)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate with (R)-alpha-cyano-3-phenoxybenzyl (1S)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate Beta-cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Beta-Cypermethrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance beta-cypermethrin 20Jun2014 2014 doi:10.2903/j.efsa.2014.3717
+Beta-Cypermethrin 265-898-0 65731-84-2 single chemical entity Component is identical to the substance Beta-Cypermethrin 265-898-0 65731-84-2 A reaction mixture comprising two enantiomeric pairs in ratio ca. 2:3 of (R)-alpha-cyano-3-phenoxybenzyl (1S)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate with (R)-alpha-cyano-3-phenoxybenzyl (1S)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate Beta-cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Beta-Cypermethrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance beta-cypermethrin 20Jun2014 2014 doi:10.2903/j.efsa.2014.3717
+Beta-Cypermethrin 265-898-0 65731-84-2 single chemical entity Component is identical to the substance Beta-Cypermethrin 265-898-0 65731-84-2 A reaction mixture comprising two enantiomeric pairs in ratio ca. 2:3 of (R)-alpha-cyano-3-phenoxybenzyl (1S)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate with (R)-alpha-cyano-3-phenoxybenzyl (1S)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate Beta-cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Beta-Cypermethrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance beta-cypermethrin 20Jun2014 2014 doi:10.2903/j.efsa.2014.3717
+Beta-Cypermethrin 265-898-0 65731-84-2 single chemical entity Component is identical to the substance Beta-Cypermethrin 265-898-0 65731-84-2 A reaction mixture comprising two enantiomeric pairs in ratio ca. 2:3 of (R)-alpha-cyano-3-phenoxybenzyl (1S)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate with (R)-alpha-cyano-3-phenoxybenzyl (1S)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate Beta-cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Beta-Cypermethrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance beta-cypermethrin 20Jun2014 2014 doi:10.2903/j.efsa.2014.3717
+Beta-Cypermethrin 265-898-0 65731-84-2 single chemical entity Component is identical to the substance Beta-Cypermethrin 265-898-0 65731-84-2 A reaction mixture comprising two enantiomeric pairs in ratio ca. 2:3 of (R)-alpha-cyano-3-phenoxybenzyl (1S)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate with (R)-alpha-cyano-3-phenoxybenzyl (1S)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate Beta-cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: The United Kingdom Beta-Cypermethrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance beta-cypermethrin 20Jun2014 2014 doi:10.2903/j.efsa.2014.3717
+Beta-Cypermethrin 265-898-0 65731-84-2 single chemical entity Component is identical to the substance Beta-Cypermethrin 265-898-0 65731-84-2 A reaction mixture comprising two enantiomeric pairs in ratio ca. 2:3 of (R)-alpha-cyano-3-phenoxybenzyl (1S)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate with (R)-alpha-cyano-3-phenoxybenzyl (1S)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate Beta-cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: The United Kingdom Beta-Cypermethrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance beta-cypermethrin 20Jun2014 2014 doi:10.2903/j.efsa.2014.3717
+Beta-Cypermethrin 265-898-0 65731-84-2 single chemical entity Component is identical to the substance Beta-Cypermethrin 265-898-0 65731-84-2 A reaction mixture comprising two enantiomeric pairs in ratio ca. 2:3 of (R)-alpha-cyano-3-phenoxybenzyl (1S)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate with (R)-alpha-cyano-3-phenoxybenzyl (1S)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate Beta-cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: The United Kingdom Beta-Cypermethrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance beta-cypermethrin 20Jun2014 2014 doi:10.2903/j.efsa.2014.3717
+Beta-Cypermethrin 265-898-0 65731-84-2 single chemical entity Component is identical to the substance Beta-Cypermethrin 265-898-0 65731-84-2 A reaction mixture comprising two enantiomeric pairs in ratio ca. 2:3 of (R)-alpha-cyano-3-phenoxybenzyl (1S)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate with (R)-alpha-cyano-3-phenoxybenzyl (1S)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate Beta-cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: The United Kingdom Beta-Cypermethrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance beta-cypermethrin 20Jun2014 2014 doi:10.2903/j.efsa.2014.3717
+Beta-Cypermethrin 265-898-0 65731-84-2 single chemical entity Component is identical to the substance Beta-Cypermethrin 265-898-0 65731-84-2 A reaction mixture comprising two enantiomeric pairs in ratio ca. 2:3 of (R)-alpha-cyano-3-phenoxybenzyl (1S)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate with (R)-alpha-cyano-3-phenoxybenzyl (1S)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate Beta-cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 Male/Female intraperitoneal 24.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity$indirect evidence-systemic toxicity RMS: The United Kingdom Beta-Cypermethrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance beta-cypermethrin 20Jun2014 2014 doi:10.2903/j.efsa.2014.3717
+Beta-Cypermethrin 265-898-0 65731-84-2 single chemical entity Component is identical to the substance Beta-Cypermethrin 265-898-0 65731-84-2 A reaction mixture comprising two enantiomeric pairs in ratio ca. 2:3 of (R)-alpha-cyano-3-phenoxybenzyl (1S)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate with (R)-alpha-cyano-3-phenoxybenzyl (1S)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate Beta-cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 Male/Female intraperitoneal 48.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity$indirect evidence-systemic toxicity RMS: The United Kingdom Beta-Cypermethrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance beta-cypermethrin 20Jun2014 2014 doi:10.2903/j.efsa.2014.3717
+Beta-Cypermethrin 265-898-0 65731-84-2 single chemical entity Component is identical to the substance Beta-Cypermethrin 265-898-0 65731-84-2 A reaction mixture comprising two enantiomeric pairs in ratio ca. 2:3 of (R)-alpha-cyano-3-phenoxybenzyl (1S)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate with (R)-alpha-cyano-3-phenoxybenzyl (1S)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate Beta-cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 Male/Female intraperitoneal 72.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity$indirect evidence-systemic toxicity RMS: The United Kingdom Beta-Cypermethrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance beta-cypermethrin 20Jun2014 2014 doi:10.2903/j.efsa.2014.3717
+Bifenox 255-894-7 42576-02-3 single chemical entity Component is identical to the substance Bifenox 255-894-7 42576-02-3 methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate Bifenox C14H9Cl2NO5 [O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Belgium Bifenox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox 14Feb2008 2008 doi:10.2903/j.efsa.2008.119r
+Bifenox 255-894-7 42576-02-3 single chemical entity Component is identical to the substance Bifenox 255-894-7 42576-02-3 methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate Bifenox C14H9Cl2NO5 [O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Belgium Bifenox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox 14Feb2008 2008 doi:10.2903/j.efsa.2008.119r
+Bifenox 255-894-7 42576-02-3 single chemical entity Component is identical to the substance Bifenox 255-894-7 42576-02-3 methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate Bifenox C14H9Cl2NO5 [O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes with Negative RMS: Belgium Bifenox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox 14Feb2008 2008 doi:10.2903/j.efsa.2008.119r
+Bifenox 255-894-7 42576-02-3 single chemical entity Component is identical to the substance Bifenox 255-894-7 42576-02-3 methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate Bifenox C14H9Cl2NO5 [O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Belgium Bifenox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox 14Feb2008 2008 doi:10.2903/j.efsa.2008.119r
+Bifenox 255-894-7 42576-02-3 single chemical entity Component is identical to the substance Bifenox 255-894-7 42576-02-3 methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate Bifenox C14H9Cl2NO5 [O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Belgium Bifenox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox 14Feb2008 2008 doi:10.2903/j.efsa.2008.119r
+Bifenox 255-894-7 42576-02-3 single chemical entity Component is identical to the substance Bifenox 255-894-7 42576-02-3 methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate Bifenox C14H9Cl2NO5 [O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Belgium Bifenox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox 14Feb2008 2008 doi:10.2903/j.efsa.2008.119r
+Bifenox 255-894-7 42576-02-3 single chemical entity Component is identical to the substance Bifenox 255-894-7 42576-02-3 methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate Bifenox C14H9Cl2NO5 [O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Belgium Bifenox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox 14Feb2008 2008 doi:10.2903/j.efsa.2008.119r
+Bifenox 255-894-7 42576-02-3 single chemical entity Component is identical to the substance Bifenox 255-894-7 42576-02-3 methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate Bifenox C14H9Cl2NO5 [O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: Belgium Bifenox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox 14Feb2008 2008 doi:10.2903/j.efsa.2008.119r
+Bifenox 255-894-7 42576-02-3 single chemical entity Component is identical to the substance Bifenox 255-894-7 42576-02-3 methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate Bifenox C14H9Cl2NO5 [O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: Belgium Bifenox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox 14Feb2008 2008 doi:10.2903/j.efsa.2008.119r
+Bifenox 255-894-7 42576-02-3 single chemical entity Component is identical to the substance Bifenox 255-894-7 42576-02-3 methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate Bifenox C14H9Cl2NO5 [O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Belgium Bifenox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox 14Feb2008 2008 doi:10.2903/j.efsa.2008.119r
+Bifenox 255-894-7 42576-02-3 single chemical entity Component is identical to the substance Bifenox 255-894-7 42576-02-3 methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate Bifenox C14H9Cl2NO5 [O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Belgium Bifenox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox 14Feb2008 2008 doi:10.2903/j.efsa.2008.119r
+Bifenox 255-894-7 42576-02-3 single chemical entity Component is identical to the substance Bifenox 255-894-7 42576-02-3 methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate Bifenox C14H9Cl2NO5 [O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes without Negative RMS: Belgium Bifenox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox 14Feb2008 2008 doi:10.2903/j.efsa.2008.119r
+Bifenox 255-894-7 42576-02-3 single chemical entity Component is identical to the substance Bifenox 255-894-7 42576-02-3 methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate Bifenox C14H9Cl2NO5 [O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no without Negative RMS: Belgium Bifenox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox 14Feb2008 2008 doi:10.2903/j.efsa.2008.119r
+Bifenox 255-894-7 42576-02-3 single chemical entity Component is identical to the substance Bifenox 255-894-7 42576-02-3 methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate Bifenox C14H9Cl2NO5 [O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no with Negative RMS: Belgium Bifenox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox 14Feb2008 2008 doi:10.2903/j.efsa.2008.119r
+Bifenox 255-894-7 42576-02-3 single chemical entity Component is identical to the substance Bifenox 255-894-7 42576-02-3 methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate Bifenox C14H9Cl2NO5 [O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no without Negative RMS: Belgium Bifenox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox 14Feb2008 2008 doi:10.2903/j.efsa.2008.119r
+Bifenox 255-894-7 42576-02-3 single chemical entity Component is identical to the substance Bifenox 255-894-7 42576-02-3 methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate Bifenox C14H9Cl2NO5 [O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no without Negative RMS: Belgium Bifenox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox 14Feb2008 2008 doi:10.2903/j.efsa.2008.119r
+Bifenox 255-894-7 42576-02-3 single chemical entity Component is identical to the substance Bifenox 255-894-7 42576-02-3 methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate Bifenox C14H9Cl2NO5 [O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no with Negative RMS: Belgium Bifenox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox 14Feb2008 2008 doi:10.2903/j.efsa.2008.119r
+Bifenox 255-894-7 42576-02-3 single chemical entity Component is identical to the substance Bifenox 255-894-7 42576-02-3 methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate Bifenox C14H9Cl2NO5 [O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no with Negative RMS: Belgium Bifenox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox 14Feb2008 2008 doi:10.2903/j.efsa.2008.119r
+Bifenox 255-894-7 42576-02-3 single chemical entity Component is identical to the substance Bifenox 255-894-7 42576-02-3 methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate Bifenox C14H9Cl2NO5 [O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no without Negative RMS: Belgium Bifenox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox 14Feb2008 2008 doi:10.2903/j.efsa.2008.119r
+Bifenox 255-894-7 42576-02-3 single chemical entity Component is identical to the substance Bifenox 255-894-7 42576-02-3 methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate Bifenox C14H9Cl2NO5 [O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no with Negative RMS: Belgium Bifenox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox 14Feb2008 2008 doi:10.2903/j.efsa.2008.119r
+Bifenox 255-894-7 42576-02-3 single chemical entity Component is identical to the substance Bifenox 255-894-7 42576-02-3 methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate Bifenox C14H9Cl2NO5 [O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no without Negative RMS: Belgium Bifenox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox 14Feb2008 2008 doi:10.2903/j.efsa.2008.119r
+Bifenox 255-894-7 42576-02-3 single chemical entity Component is identical to the substance Bifenox 255-894-7 42576-02-3 methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate Bifenox C14H9Cl2NO5 [O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no with Negative RMS: Belgium Bifenox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox 14Feb2008 2008 doi:10.2903/j.efsa.2008.119r
+Bifenox 255-894-7 42576-02-3 single chemical entity Component is identical to the substance Bifenox 255-894-7 42576-02-3 methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate Bifenox C14H9Cl2NO5 [O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no with Negative RMS: Belgium Bifenox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox 14Feb2008 2008 doi:10.2903/j.efsa.2008.119r
+Bifenox 255-894-7 42576-02-3 single chemical entity Component is identical to the substance Bifenox 255-894-7 42576-02-3 methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate Bifenox C14H9Cl2NO5 [O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no without Negative RMS: Belgium Bifenox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox 14Feb2008 2008 doi:10.2903/j.efsa.2008.119r
+Bifenox 255-894-7 42576-02-3 single chemical entity Component is identical to the substance Bifenox 255-894-7 42576-02-3 methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate Bifenox C14H9Cl2NO5 [O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: Belgium Bifenox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox 14Feb2008 2008 doi:10.2903/j.efsa.2008.119r
+Bifenox 255-894-7 42576-02-3 single chemical entity Component is identical to the substance Bifenox 255-894-7 42576-02-3 methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate Bifenox C14H9Cl2NO5 [O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Belgium Bifenox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox 14Feb2008 2008 doi:10.2903/j.efsa.2008.119r
+Bifenox 255-894-7 42576-02-3 single chemical entity Component is identical to the substance Bifenox 255-894-7 42576-02-3 methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate Bifenox C14H9Cl2NO5 [O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Belgium Bifenox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox 14Feb2008 2008 doi:10.2903/j.efsa.2008.119r
+Bifenox 255-894-7 42576-02-3 single chemical entity Component is identical to the substance Bifenox 255-894-7 42576-02-3 methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate Bifenox C14H9Cl2NO5 [O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Belgium Bifenox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox 14Feb2008 2008 doi:10.2903/j.efsa.2008.119r
+Bifenox 255-894-7 42576-02-3 single chemical entity Component is identical to the substance Bifenox 255-894-7 42576-02-3 methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate Bifenox C14H9Cl2NO5 [O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: Belgium Bifenox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox 14Feb2008 2008 doi:10.2903/j.efsa.2008.119r
+Bifenox 255-894-7 42576-02-3 single chemical entity Component is identical to the substance Bifenox 255-894-7 42576-02-3 methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate Bifenox C14H9Cl2NO5 [O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Belgium Bifenox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox 14Feb2008 2008 doi:10.2903/j.efsa.2008.119r
+Bifenox 255-894-7 42576-02-3 single chemical entity Component is identical to the substance Bifenox 255-894-7 42576-02-3 methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate Bifenox C14H9Cl2NO5 [O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Belgium Bifenox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox 14Feb2008 2008 doi:10.2903/j.efsa.2008.119r
+Bifenox 255-894-7 42576-02-3 single chemical entity Component is identical to the substance Bifenox 255-894-7 42576-02-3 methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate Bifenox C14H9Cl2NO5 [O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Belgium Bifenox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox 14Feb2008 2008 doi:10.2903/j.efsa.2008.119r
+Bifenox 255-894-7 42576-02-3 single chemical entity Component is identical to the substance Bifenox 255-894-7 42576-02-3 methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate Bifenox C14H9Cl2NO5 [O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Belgium Bifenox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox 14Feb2008 2008 doi:10.2903/j.efsa.2008.119r
+Bifenox 255-894-7 42576-02-3 single chemical entity Component is identical to the substance Bifenox 255-894-7 42576-02-3 methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate Bifenox C14H9Cl2NO5 [O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Belgium Bifenox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox 14Feb2008 2008 doi:10.2903/j.efsa.2008.119r
+Bifenox 255-894-7 42576-02-3 single chemical entity Component is identical to the substance Bifenox 255-894-7 42576-02-3 methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate Bifenox C14H9Cl2NO5 [O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: Belgium Bifenox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox 14Feb2008 2008 doi:10.2903/j.efsa.2008.119r
+Bifenox 255-894-7 42576-02-3 single chemical entity Component is identical to the substance Bifenox 255-894-7 42576-02-3 methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate Bifenox C14H9Cl2NO5 [O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Belgium Bifenox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox 14Feb2008 2008 doi:10.2903/j.efsa.2008.119r
+Bifenox 255-894-7 42576-02-3 single chemical entity Component is identical to the substance Bifenox 255-894-7 42576-02-3 methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate Bifenox C14H9Cl2NO5 [O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Belgium Bifenox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox 14Feb2008 2008 doi:10.2903/j.efsa.2008.119r
+Bifenox 255-894-7 42576-02-3 single chemical entity Component is identical to the substance Bifenox 255-894-7 42576-02-3 methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate Bifenox C14H9Cl2NO5 [O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Belgium Bifenox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox 14Feb2008 2008 doi:10.2903/j.efsa.2008.119r
+Bifenox 255-894-7 42576-02-3 single chemical entity Component is identical to the substance Bifenox 255-894-7 42576-02-3 methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate Bifenox C14H9Cl2NO5 [O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Belgium Bifenox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox 14Feb2008 2008 doi:10.2903/j.efsa.2008.119r
+Bifenox 255-894-7 42576-02-3 single chemical entity Component is identical to the substance Bifenox 255-894-7 42576-02-3 methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate Bifenox C14H9Cl2NO5 [O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Belgium Bifenox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox 14Feb2008 2008 doi:10.2903/j.efsa.2008.119r
+Bifenox 255-894-7 42576-02-3 single chemical entity Component is identical to the substance Bifenox 255-894-7 42576-02-3 methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate Bifenox C14H9Cl2NO5 [O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Belgium Bifenox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox 14Feb2008 2008 doi:10.2903/j.efsa.2008.119r
+Bifenox 255-894-7 42576-02-3 single chemical entity Component is identical to the substance Bifenox 255-894-7 42576-02-3 methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate Bifenox C14H9Cl2NO5 [O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Belgium Bifenox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox 14Feb2008 2008 doi:10.2903/j.efsa.2008.119r
+Bifenox 255-894-7 42576-02-3 single chemical entity Component is identical to the substance Bifenox 255-894-7 42576-02-3 methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate Bifenox C14H9Cl2NO5 [O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Belgium Bifenox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox 14Feb2008 2008 doi:10.2903/j.efsa.2008.119r
+Bifenox 255-894-7 42576-02-3 single chemical entity Component is identical to the substance Bifenox 255-894-7 42576-02-3 methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate Bifenox C14H9Cl2NO5 [O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: Belgium Bifenox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox 14Feb2008 2008 doi:10.2903/j.efsa.2008.119r
+Bifenox 255-894-7 42576-02-3 single chemical entity Component is identical to the substance Bifenox 255-894-7 42576-02-3 methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate Bifenox C14H9Cl2NO5 [O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: Belgium Bifenox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox 14Feb2008 2008 doi:10.2903/j.efsa.2008.119r
+Bifenox 255-894-7 42576-02-3 single chemical entity Component is identical to the substance Bifenox 255-894-7 42576-02-3 methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate Bifenox C14H9Cl2NO5 [O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: Belgium Bifenox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox 14Feb2008 2008 doi:10.2903/j.efsa.2008.119r
+Bifenox 255-894-7 42576-02-3 single chemical entity Component is identical to the substance Bifenox 255-894-7 42576-02-3 methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate Bifenox C14H9Cl2NO5 [O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative large colonies RMS: Belgium Bifenox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox 14Feb2008 2008 doi:10.2903/j.efsa.2008.119r
+Bifenox 255-894-7 42576-02-3 single chemical entity Component is identical to the substance Bifenox 255-894-7 42576-02-3 methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate Bifenox C14H9Cl2NO5 [O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative small colonies RMS: Belgium Bifenox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox 14Feb2008 2008 doi:10.2903/j.efsa.2008.119r
+Bifenox 255-894-7 42576-02-3 single chemical entity Component is identical to the substance Bifenox 255-894-7 42576-02-3 methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate Bifenox C14H9Cl2NO5 [O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative small colonies RMS: Belgium Bifenox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox 14Feb2008 2008 doi:10.2903/j.efsa.2008.119r
+Bifenox 255-894-7 42576-02-3 single chemical entity Component is identical to the substance Bifenox 255-894-7 42576-02-3 methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate Bifenox C14H9Cl2NO5 [O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative large colonies RMS: Belgium Bifenox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox 14Feb2008 2008 doi:10.2903/j.efsa.2008.119r
+Bifenox 255-894-7 42576-02-3 single chemical entity Component is identical to the substance Bifenox 255-894-7 42576-02-3 methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate Bifenox C14H9Cl2NO5 [O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative no information RMS: Belgium Bifenox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox 14Feb2008 2008 doi:10.2903/j.efsa.2008.119r
+Bifenox 255-894-7 42576-02-3 single chemical entity Component is identical to the substance Bifenox 255-894-7 42576-02-3 methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate Bifenox C14H9Cl2NO5 [O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Negative no information RMS: Belgium Bifenox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox 14Feb2008 2008 doi:10.2903/j.efsa.2008.119r
+Bifenox 255-894-7 42576-02-3 single chemical entity Component is identical to the substance Bifenox 255-894-7 42576-02-3 methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate Bifenox C14H9Cl2NO5 [O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: Belgium Bifenox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox 14Feb2008 2008 doi:10.2903/j.efsa.2008.119r
+Bifenox 255-894-7 42576-02-3 single chemical entity Component is identical to the substance Bifenox 255-894-7 42576-02-3 methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate Bifenox C14H9Cl2NO5 [O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: Belgium Bifenox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox 14Feb2008 2008 doi:10.2903/j.efsa.2008.119r
+Bifenox 255-894-7 42576-02-3 single chemical entity Component is identical to the substance Bifenox 255-894-7 42576-02-3 methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate Bifenox C14H9Cl2NO5 [O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 24.0000000000 h yes not applicable Negative no evidence RMS: Belgium Bifenox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox 14Feb2008 2008 doi:10.2903/j.efsa.2008.119r
+Bifenox 255-894-7 42576-02-3 single chemical entity Component is identical to the substance Bifenox 255-894-7 42576-02-3 methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate Bifenox C14H9Cl2NO5 [O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 48.0000000000 h yes not applicable Negative no evidence RMS: Belgium Bifenox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox 14Feb2008 2008 doi:10.2903/j.efsa.2008.119r
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is identical to the substance Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl 2000 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is identical to the substance Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl 2000 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is identical to the substance Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl 2000 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is identical to the substance Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl 2000 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is identical to the substance Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl 2000 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is identical to the substance Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl 2000 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is identical to the substance Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl 2000 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is identical to the substance Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl 2000 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is identical to the substance Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl 2000 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is identical to the substance Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl 2000 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is identical to the substance Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl (Addendum 8) 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is identical to the substance Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl (Addendum 8) 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is identical to the substance Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl (Addendum 8) 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is identical to the substance Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl (Addendum 8) 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is identical to the substance Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl (Addendum 8) 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is identical to the substance Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl (Addendum 8) 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is identical to the substance Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl (Addendum 8) 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is identical to the substance Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl (Addendum 8) 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is identical to the substance Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl (Addendum 8) 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is identical to the substance Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl (Addendum 8) 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is a metabolite of the substance Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate 3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid Not in list C15H19NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative small colonies RMS: Portugal Benalaxyl (Addendum 8) 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is a metabolite of the substance Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate 3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid Not in list C15H19NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative large colonies RMS: Portugal Benalaxyl (Addendum 8) 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is a metabolite of the substance Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate 3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid Not in list C15H19NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative large colonies RMS: Portugal Benalaxyl (Addendum 8) 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is a metabolite of the substance Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate 3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid Not in list C15H19NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative small colonies RMS: Portugal Benalaxyl (Addendum 8) 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate 3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid Not in list C15H19NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative large colonies RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate 3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid Not in list C15H19NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative small colonies RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate 3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid Not in list C15H19NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative small colonies RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate 3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid Not in list C15H19NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative large colonies RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate 3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid Not in list C15H19NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate 3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid Not in list C15H19NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate 3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid Not in list C15H19NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate 3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid Not in list C15H19NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate 3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid Not in list C15H19NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate 3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid Not in list C15H19NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate 3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid Not in list C15H19NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate 3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid Not in list C15H19NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate 3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid Not in list C15H19NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate 3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid Not in list C15H19NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is a metabolite of the substance Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate 3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid Not in list C15H19NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl (Addendum 8) 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is a metabolite of the substance Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate 3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid Not in list C15H19NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl (Addendum 8) 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is a metabolite of the substance Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate 3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid Not in list C15H19NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl (Addendum 8) 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is a metabolite of the substance Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate 3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid Not in list C15H19NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl (Addendum 8) 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is a metabolite of the substance Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate 3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid Not in list C15H19NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl (Addendum 8) 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is a metabolite of the substance Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate 3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid Not in list C15H19NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl (Addendum 8) 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is a metabolite of the substance Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate 3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid Not in list C15H19NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl (Addendum 8) 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is a metabolite of the substance Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate 3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid Not in list C15H19NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl (Addendum 8) 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is a metabolite of the substance Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate 3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid Not in list C15H19NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl (Addendum 8) 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is a metabolite of the substance Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate 3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid Not in list C15H19NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl (Addendum 8) 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is a metabolite of the substance N-(malonyl)-N-(2,6-xylyl)-DL-alanine N-(carboxyacetyl)-N-(2,6-dimethylphenyl)alanine Not in list C14H17NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)O InChI=1S/C14H17NO5/c1-8-5-4-6-9(2)13(8)15(10(3)14(19)20)11(16)7-12(17)18/h4-6,10H,7H2,1-3H3,(H,17,18)(H,19,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl (Addendum 8) 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is a metabolite of the substance N-(malonyl)-N-(2,6-xylyl)-DL-alanine N-(carboxyacetyl)-N-(2,6-dimethylphenyl)alanine Not in list C14H17NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)O InChI=1S/C14H17NO5/c1-8-5-4-6-9(2)13(8)15(10(3)14(19)20)11(16)7-12(17)18/h4-6,10H,7H2,1-3H3,(H,17,18)(H,19,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl (Addendum 8) 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is a metabolite of the substance N-(malonyl)-N-(2,6-xylyl)-DL-alanine N-(carboxyacetyl)-N-(2,6-dimethylphenyl)alanine Not in list C14H17NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)O InChI=1S/C14H17NO5/c1-8-5-4-6-9(2)13(8)15(10(3)14(19)20)11(16)7-12(17)18/h4-6,10H,7H2,1-3H3,(H,17,18)(H,19,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl (Addendum 8) 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is a metabolite of the substance N-(malonyl)-N-(2,6-xylyl)-DL-alanine N-(carboxyacetyl)-N-(2,6-dimethylphenyl)alanine Not in list C14H17NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)O InChI=1S/C14H17NO5/c1-8-5-4-6-9(2)13(8)15(10(3)14(19)20)11(16)7-12(17)18/h4-6,10H,7H2,1-3H3,(H,17,18)(H,19,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl (Addendum 8) 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is a metabolite of the substance N-(malonyl)-N-(2,6-xylyl)-DL-alanine N-(carboxyacetyl)-N-(2,6-dimethylphenyl)alanine Not in list C14H17NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)O InChI=1S/C14H17NO5/c1-8-5-4-6-9(2)13(8)15(10(3)14(19)20)11(16)7-12(17)18/h4-6,10H,7H2,1-3H3,(H,17,18)(H,19,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl (Addendum 8) 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is a metabolite of the substance N-(malonyl)-N-(2,6-xylyl)-DL-alanine N-(carboxyacetyl)-N-(2,6-dimethylphenyl)alanine Not in list C14H17NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)O InChI=1S/C14H17NO5/c1-8-5-4-6-9(2)13(8)15(10(3)14(19)20)11(16)7-12(17)18/h4-6,10H,7H2,1-3H3,(H,17,18)(H,19,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl (Addendum 8) 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is a metabolite of the substance N-(malonyl)-N-(2,6-xylyl)-DL-alanine N-(carboxyacetyl)-N-(2,6-dimethylphenyl)alanine Not in list C14H17NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)O InChI=1S/C14H17NO5/c1-8-5-4-6-9(2)13(8)15(10(3)14(19)20)11(16)7-12(17)18/h4-6,10H,7H2,1-3H3,(H,17,18)(H,19,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl (Addendum 8) 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is a metabolite of the substance N-(malonyl)-N-(2,6-xylyl)-DL-alanine N-(carboxyacetyl)-N-(2,6-dimethylphenyl)alanine Not in list C14H17NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)O InChI=1S/C14H17NO5/c1-8-5-4-6-9(2)13(8)15(10(3)14(19)20)11(16)7-12(17)18/h4-6,10H,7H2,1-3H3,(H,17,18)(H,19,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl (Addendum 8) 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is a metabolite of the substance N-(malonyl)-N-(2,6-xylyl)-DL-alanine N-(carboxyacetyl)-N-(2,6-dimethylphenyl)alanine Not in list C14H17NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)O InChI=1S/C14H17NO5/c1-8-5-4-6-9(2)13(8)15(10(3)14(19)20)11(16)7-12(17)18/h4-6,10H,7H2,1-3H3,(H,17,18)(H,19,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl (Addendum 8) 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is a metabolite of the substance N-(malonyl)-N-(2,6-xylyl)-DL-alanine N-(carboxyacetyl)-N-(2,6-dimethylphenyl)alanine Not in list C14H17NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)O InChI=1S/C14H17NO5/c1-8-5-4-6-9(2)13(8)15(10(3)14(19)20)11(16)7-12(17)18/h4-6,10H,7H2,1-3H3,(H,17,18)(H,19,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl (Addendum 8) 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance N-(malonyl)-N-(2,6-xylyl)-DL-alanine N-(carboxyacetyl)-N-(2,6-dimethylphenyl)alanine Not in list C14H17NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)O InChI=1S/C14H17NO5/c1-8-5-4-6-9(2)13(8)15(10(3)14(19)20)11(16)7-12(17)18/h4-6,10H,7H2,1-3H3,(H,17,18)(H,19,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance N-(malonyl)-N-(2,6-xylyl)-DL-alanine N-(carboxyacetyl)-N-(2,6-dimethylphenyl)alanine Not in list C14H17NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)O InChI=1S/C14H17NO5/c1-8-5-4-6-9(2)13(8)15(10(3)14(19)20)11(16)7-12(17)18/h4-6,10H,7H2,1-3H3,(H,17,18)(H,19,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance N-(malonyl)-N-(2,6-xylyl)-DL-alanine N-(carboxyacetyl)-N-(2,6-dimethylphenyl)alanine Not in list C14H17NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)O InChI=1S/C14H17NO5/c1-8-5-4-6-9(2)13(8)15(10(3)14(19)20)11(16)7-12(17)18/h4-6,10H,7H2,1-3H3,(H,17,18)(H,19,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance N-(malonyl)-N-(2,6-xylyl)-DL-alanine N-(carboxyacetyl)-N-(2,6-dimethylphenyl)alanine Not in list C14H17NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)O InChI=1S/C14H17NO5/c1-8-5-4-6-9(2)13(8)15(10(3)14(19)20)11(16)7-12(17)18/h4-6,10H,7H2,1-3H3,(H,17,18)(H,19,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance N-(malonyl)-N-(2,6-xylyl)-DL-alanine N-(carboxyacetyl)-N-(2,6-dimethylphenyl)alanine Not in list C14H17NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)O InChI=1S/C14H17NO5/c1-8-5-4-6-9(2)13(8)15(10(3)14(19)20)11(16)7-12(17)18/h4-6,10H,7H2,1-3H3,(H,17,18)(H,19,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance N-(malonyl)-N-(2,6-xylyl)-DL-alanine N-(carboxyacetyl)-N-(2,6-dimethylphenyl)alanine Not in list C14H17NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)O InChI=1S/C14H17NO5/c1-8-5-4-6-9(2)13(8)15(10(3)14(19)20)11(16)7-12(17)18/h4-6,10H,7H2,1-3H3,(H,17,18)(H,19,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance N-(malonyl)-N-(2,6-xylyl)-DL-alanine N-(carboxyacetyl)-N-(2,6-dimethylphenyl)alanine Not in list C14H17NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)O InChI=1S/C14H17NO5/c1-8-5-4-6-9(2)13(8)15(10(3)14(19)20)11(16)7-12(17)18/h4-6,10H,7H2,1-3H3,(H,17,18)(H,19,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance N-(malonyl)-N-(2,6-xylyl)-DL-alanine N-(carboxyacetyl)-N-(2,6-dimethylphenyl)alanine Not in list C14H17NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)O InChI=1S/C14H17NO5/c1-8-5-4-6-9(2)13(8)15(10(3)14(19)20)11(16)7-12(17)18/h4-6,10H,7H2,1-3H3,(H,17,18)(H,19,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance N-(malonyl)-N-(2,6-xylyl)-DL-alanine N-(carboxyacetyl)-N-(2,6-dimethylphenyl)alanine Not in list C14H17NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)O InChI=1S/C14H17NO5/c1-8-5-4-6-9(2)13(8)15(10(3)14(19)20)11(16)7-12(17)18/h4-6,10H,7H2,1-3H3,(H,17,18)(H,19,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance N-(malonyl)-N-(2,6-xylyl)-DL-alanine N-(carboxyacetyl)-N-(2,6-dimethylphenyl)alanine Not in list C14H17NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)O InChI=1S/C14H17NO5/c1-8-5-4-6-9(2)13(8)15(10(3)14(19)20)11(16)7-12(17)18/h4-6,10H,7H2,1-3H3,(H,17,18)(H,19,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance N-(malonyl)-N-(2,6-xylyl)-DL-alanine N-(carboxyacetyl)-N-(2,6-dimethylphenyl)alanine Not in list C14H17NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)O InChI=1S/C14H17NO5/c1-8-5-4-6-9(2)13(8)15(10(3)14(19)20)11(16)7-12(17)18/h4-6,10H,7H2,1-3H3,(H,17,18)(H,19,20) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative small colonies RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance N-(malonyl)-N-(2,6-xylyl)-DL-alanine N-(carboxyacetyl)-N-(2,6-dimethylphenyl)alanine Not in list C14H17NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)O InChI=1S/C14H17NO5/c1-8-5-4-6-9(2)13(8)15(10(3)14(19)20)11(16)7-12(17)18/h4-6,10H,7H2,1-3H3,(H,17,18)(H,19,20) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Negative small colonies RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance N-(malonyl)-N-(2,6-xylyl)-DL-alanine N-(carboxyacetyl)-N-(2,6-dimethylphenyl)alanine Not in list C14H17NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)O InChI=1S/C14H17NO5/c1-8-5-4-6-9(2)13(8)15(10(3)14(19)20)11(16)7-12(17)18/h4-6,10H,7H2,1-3H3,(H,17,18)(H,19,20) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Negative large colonies RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance N-(malonyl)-N-(2,6-xylyl)-DL-alanine N-(carboxyacetyl)-N-(2,6-dimethylphenyl)alanine Not in list C14H17NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)O InChI=1S/C14H17NO5/c1-8-5-4-6-9(2)13(8)15(10(3)14(19)20)11(16)7-12(17)18/h4-6,10H,7H2,1-3H3,(H,17,18)(H,19,20) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative large colonies RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is a metabolite of the substance N-(malonyl)-N-(2,6-xylyl)-DL-alanine N-(carboxyacetyl)-N-(2,6-dimethylphenyl)alanine Not in list C14H17NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)O InChI=1S/C14H17NO5/c1-8-5-4-6-9(2)13(8)15(10(3)14(19)20)11(16)7-12(17)18/h4-6,10H,7H2,1-3H3,(H,17,18)(H,19,20) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Negative small colonies RMS: Portugal Benalaxyl (Addendum 8) 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is a metabolite of the substance N-(malonyl)-N-(2,6-xylyl)-DL-alanine N-(carboxyacetyl)-N-(2,6-dimethylphenyl)alanine Not in list C14H17NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)O InChI=1S/C14H17NO5/c1-8-5-4-6-9(2)13(8)15(10(3)14(19)20)11(16)7-12(17)18/h4-6,10H,7H2,1-3H3,(H,17,18)(H,19,20) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative small colonies RMS: Portugal Benalaxyl (Addendum 8) 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is a metabolite of the substance N-(malonyl)-N-(2,6-xylyl)-DL-alanine N-(carboxyacetyl)-N-(2,6-dimethylphenyl)alanine Not in list C14H17NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)O InChI=1S/C14H17NO5/c1-8-5-4-6-9(2)13(8)15(10(3)14(19)20)11(16)7-12(17)18/h4-6,10H,7H2,1-3H3,(H,17,18)(H,19,20) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative large colonies RMS: Portugal Benalaxyl (Addendum 8) 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl 275-728-7 71626-11-4 single chemical entity Component is a metabolite of the substance N-(malonyl)-N-(2,6-xylyl)-DL-alanine N-(carboxyacetyl)-N-(2,6-dimethylphenyl)alanine Not in list C14H17NO5 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)O InChI=1S/C14H17NO5/c1-8-5-4-6-9(2)13(8)15(10(3)14(19)20)11(16)7-12(17)18/h4-6,10H,7H2,1-3H3,(H,17,18)(H,19,20) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Negative large colonies RMS: Portugal Benalaxyl (Addendum 8) 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Positive RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Positive RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is a metabolite of the substance 6-Fluoro-2-hydroxybenzothiazole 6-fluoro-1,3-benzothiazol-2-ol Not in list C7H4FNOS Fc1ccc2nc(O)sc2c1 InChI=1/C7H4FNOS/c8-4-1-2-5-6(3-4)11-7(10)9-5/h1-3H,(H,9,10) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is a metabolite of the substance 6-Fluoro-2-hydroxybenzothiazole 6-fluoro-1,3-benzothiazol-2-ol Not in list C7H4FNOS Fc1ccc2nc(O)sc2c1 InChI=1/C7H4FNOS/c8-4-1-2-5-6(3-4)11-7(10)9-5/h1-3H,(H,9,10) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is a metabolite of the substance 6-Fluoro-2-hydroxybenzothiazole 6-fluoro-1,3-benzothiazol-2-ol Not in list C7H4FNOS Fc1ccc2nc(O)sc2c1 InChI=1/C7H4FNOS/c8-4-1-2-5-6(3-4)11-7(10)9-5/h1-3H,(H,9,10) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is a metabolite of the substance 6-Fluoro-2-hydroxybenzothiazole 6-fluoro-1,3-benzothiazol-2-ol Not in list C7H4FNOS Fc1ccc2nc(O)sc2c1 InChI=1/C7H4FNOS/c8-4-1-2-5-6(3-4)11-7(10)9-5/h1-3H,(H,9,10) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is a metabolite of the substance 6-Fluoro-2-hydroxybenzothiazole 6-fluoro-1,3-benzothiazol-2-ol Not in list C7H4FNOS Fc1ccc2nc(O)sc2c1 InChI=1/C7H4FNOS/c8-4-1-2-5-6(3-4)11-7(10)9-5/h1-3H,(H,9,10) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is a metabolite of the substance 6-Fluoro-2-hydroxybenzothiazole 6-fluoro-1,3-benzothiazol-2-ol Not in list C7H4FNOS Fc1ccc2nc(O)sc2c1 InChI=1/C7H4FNOS/c8-4-1-2-5-6(3-4)11-7(10)9-5/h1-3H,(H,9,10) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is a metabolite of the substance 6-Fluoro-2-hydroxybenzothiazole 6-fluoro-1,3-benzothiazol-2-ol Not in list C7H4FNOS Fc1ccc2nc(O)sc2c1 InChI=1/C7H4FNOS/c8-4-1-2-5-6(3-4)11-7(10)9-5/h1-3H,(H,9,10) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is a metabolite of the substance 6-Fluoro-2-hydroxybenzothiazole 6-fluoro-1,3-benzothiazol-2-ol Not in list C7H4FNOS Fc1ccc2nc(O)sc2c1 InChI=1/C7H4FNOS/c8-4-1-2-5-6(3-4)11-7(10)9-5/h1-3H,(H,9,10) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is a metabolite of the substance 6-Fluoro-2-hydroxybenzothiazole 6-fluoro-1,3-benzothiazol-2-ol Not in list C7H4FNOS Fc1ccc2nc(O)sc2c1 InChI=1/C7H4FNOS/c8-4-1-2-5-6(3-4)11-7(10)9-5/h1-3H,(H,9,10) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is a metabolite of the substance 6-Fluoro-2-hydroxybenzothiazole 6-fluoro-1,3-benzothiazol-2-ol Not in list C7H4FNOS Fc1ccc2nc(O)sc2c1 InChI=1/C7H4FNOS/c8-4-1-2-5-6(3-4)11-7(10)9-5/h1-3H,(H,9,10) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is a metabolite of the substance 1-(6-Fluorobenzothiazol-2-yl)ethanol 1-(6-fluoro-1,3-benzothiazol-2-yl)ethanol Not in list C9H8FNOS CC(O)c1nc2ccc(F)cc2s1 InChI=1/C9H8FNOS/c1-5(12)9-11-7-3-2-6(10)4-8(7)13-9/h2-5,12H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is a metabolite of the substance 1-(6-Fluorobenzothiazol-2-yl)ethanol 1-(6-fluoro-1,3-benzothiazol-2-yl)ethanol Not in list C9H8FNOS CC(O)c1nc2ccc(F)cc2s1 InChI=1/C9H8FNOS/c1-5(12)9-11-7-3-2-6(10)4-8(7)13-9/h2-5,12H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is a metabolite of the substance 1-(6-Fluorobenzothiazol-2-yl)ethanol 1-(6-fluoro-1,3-benzothiazol-2-yl)ethanol Not in list C9H8FNOS CC(O)c1nc2ccc(F)cc2s1 InChI=1/C9H8FNOS/c1-5(12)9-11-7-3-2-6(10)4-8(7)13-9/h2-5,12H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is a metabolite of the substance 1-(6-Fluorobenzothiazol-2-yl)ethanol 1-(6-fluoro-1,3-benzothiazol-2-yl)ethanol Not in list C9H8FNOS CC(O)c1nc2ccc(F)cc2s1 InChI=1/C9H8FNOS/c1-5(12)9-11-7-3-2-6(10)4-8(7)13-9/h2-5,12H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is a metabolite of the substance 1-(6-Fluorobenzothiazol-2-yl)ethanol 1-(6-fluoro-1,3-benzothiazol-2-yl)ethanol Not in list C9H8FNOS CC(O)c1nc2ccc(F)cc2s1 InChI=1/C9H8FNOS/c1-5(12)9-11-7-3-2-6(10)4-8(7)13-9/h2-5,12H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is a metabolite of the substance 1-(6-Fluorobenzothiazol-2-yl)ethanol 1-(6-fluoro-1,3-benzothiazol-2-yl)ethanol Not in list C9H8FNOS CC(O)c1nc2ccc(F)cc2s1 InChI=1/C9H8FNOS/c1-5(12)9-11-7-3-2-6(10)4-8(7)13-9/h2-5,12H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is a metabolite of the substance 1-(6-Fluorobenzothiazol-2-yl)ethanol 1-(6-fluoro-1,3-benzothiazol-2-yl)ethanol Not in list C9H8FNOS CC(O)c1nc2ccc(F)cc2s1 InChI=1/C9H8FNOS/c1-5(12)9-11-7-3-2-6(10)4-8(7)13-9/h2-5,12H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is a metabolite of the substance 1-(6-Fluorobenzothiazol-2-yl)ethanol 1-(6-fluoro-1,3-benzothiazol-2-yl)ethanol Not in list C9H8FNOS CC(O)c1nc2ccc(F)cc2s1 InChI=1/C9H8FNOS/c1-5(12)9-11-7-3-2-6(10)4-8(7)13-9/h2-5,12H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is a metabolite of the substance 1-(6-Fluorobenzothiazol-2-yl)ethanol 1-(6-fluoro-1,3-benzothiazol-2-yl)ethanol Not in list C9H8FNOS CC(O)c1nc2ccc(F)cc2s1 InChI=1/C9H8FNOS/c1-5(12)9-11-7-3-2-6(10)4-8(7)13-9/h2-5,12H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is a metabolite of the substance 1-(6-Fluorobenzothiazol-2-yl)ethanol 1-(6-fluoro-1,3-benzothiazol-2-yl)ethanol Not in list C9H8FNOS CC(O)c1nc2ccc(F)cc2s1 InChI=1/C9H8FNOS/c1-5(12)9-11-7-3-2-6(10)4-8(7)13-9/h2-5,12H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is a metabolite of the substance 6-Fluorobenzothiazol-2-yl methyl ketone 1-(6-fluoro-1,3-benzothiazol-2-yl)ethanone Not in list C9H6FNOS CC(=O)c1nc2ccc(F)cc2s1 InChI=1/C9H6FNOS/c1-5(12)9-11-7-3-2-6(10)4-8(7)13-9/h2-4H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is a metabolite of the substance 6-Fluorobenzothiazol-2-yl methyl ketone 1-(6-fluoro-1,3-benzothiazol-2-yl)ethanone Not in list C9H6FNOS CC(=O)c1nc2ccc(F)cc2s1 InChI=1/C9H6FNOS/c1-5(12)9-11-7-3-2-6(10)4-8(7)13-9/h2-4H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is a metabolite of the substance 6-Fluorobenzothiazol-2-yl methyl ketone 1-(6-fluoro-1,3-benzothiazol-2-yl)ethanone Not in list C9H6FNOS CC(=O)c1nc2ccc(F)cc2s1 InChI=1/C9H6FNOS/c1-5(12)9-11-7-3-2-6(10)4-8(7)13-9/h2-4H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is a metabolite of the substance 6-Fluorobenzothiazol-2-yl methyl ketone 1-(6-fluoro-1,3-benzothiazol-2-yl)ethanone Not in list C9H6FNOS CC(=O)c1nc2ccc(F)cc2s1 InChI=1/C9H6FNOS/c1-5(12)9-11-7-3-2-6(10)4-8(7)13-9/h2-4H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Positive RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is a metabolite of the substance 6-Fluorobenzothiazol-2-yl methyl ketone 1-(6-fluoro-1,3-benzothiazol-2-yl)ethanone Not in list C9H6FNOS CC(=O)c1nc2ccc(F)cc2s1 InChI=1/C9H6FNOS/c1-5(12)9-11-7-3-2-6(10)4-8(7)13-9/h2-4H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is a metabolite of the substance 6-Fluorobenzothiazol-2-yl methyl ketone 1-(6-fluoro-1,3-benzothiazol-2-yl)ethanone Not in list C9H6FNOS CC(=O)c1nc2ccc(F)cc2s1 InChI=1/C9H6FNOS/c1-5(12)9-11-7-3-2-6(10)4-8(7)13-9/h2-4H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is a metabolite of the substance 6-Fluorobenzothiazol-2-yl methyl ketone 1-(6-fluoro-1,3-benzothiazol-2-yl)ethanone Not in list C9H6FNOS CC(=O)c1nc2ccc(F)cc2s1 InChI=1/C9H6FNOS/c1-5(12)9-11-7-3-2-6(10)4-8(7)13-9/h2-4H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is a metabolite of the substance 6-Fluorobenzothiazol-2-yl methyl ketone 1-(6-fluoro-1,3-benzothiazol-2-yl)ethanone Not in list C9H6FNOS CC(=O)c1nc2ccc(F)cc2s1 InChI=1/C9H6FNOS/c1-5(12)9-11-7-3-2-6(10)4-8(7)13-9/h2-4H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is a metabolite of the substance 6-Fluorobenzothiazol-2-yl methyl ketone 1-(6-fluoro-1,3-benzothiazol-2-yl)ethanone Not in list C9H6FNOS CC(=O)c1nc2ccc(F)cc2s1 InChI=1/C9H6FNOS/c1-5(12)9-11-7-3-2-6(10)4-8(7)13-9/h2-4H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is a metabolite of the substance 6-Fluorobenzothiazol-2-yl methyl ketone 1-(6-fluoro-1,3-benzothiazol-2-yl)ethanone Not in list C9H6FNOS CC(=O)c1nc2ccc(F)cc2s1 InChI=1/C9H6FNOS/c1-5(12)9-11-7-3-2-6(10)4-8(7)13-9/h2-4H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is a metabolite of the substance 1-(6-Fluorobenzothiazol-2-yl)ethanol 1-(6-fluoro-1,3-benzothiazol-2-yl)ethanol Not in list C9H8FNOS CC(O)c1nc2ccc(F)cc2s1 InChI=1/C9H8FNOS/c1-5(12)9-11-7-3-2-6(10)4-8(7)13-9/h2-5,12H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is a metabolite of the substance 1-(6-Fluorobenzothiazol-2-yl)ethanol 1-(6-fluoro-1,3-benzothiazol-2-yl)ethanol Not in list C9H8FNOS CC(O)c1nc2ccc(F)cc2s1 InChI=1/C9H8FNOS/c1-5(12)9-11-7-3-2-6(10)4-8(7)13-9/h2-5,12H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is a metabolite of the substance 1-(6-Fluorobenzothiazol-2-yl)ethanol 1-(6-fluoro-1,3-benzothiazol-2-yl)ethanol Not in list C9H8FNOS CC(O)c1nc2ccc(F)cc2s1 InChI=1/C9H8FNOS/c1-5(12)9-11-7-3-2-6(10)4-8(7)13-9/h2-5,12H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is a metabolite of the substance 1-(6-Fluorobenzothiazol-2-yl)ethanol 1-(6-fluoro-1,3-benzothiazol-2-yl)ethanol Not in list C9H8FNOS CC(O)c1nc2ccc(F)cc2s1 InChI=1/C9H8FNOS/c1-5(12)9-11-7-3-2-6(10)4-8(7)13-9/h2-5,12H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is a metabolite of the substance 1-(6-Fluorobenzothiazol-2-yl)ethanol 1-(6-fluoro-1,3-benzothiazol-2-yl)ethanol Not in list C9H8FNOS CC(O)c1nc2ccc(F)cc2s1 InChI=1/C9H8FNOS/c1-5(12)9-11-7-3-2-6(10)4-8(7)13-9/h2-5,12H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is a metabolite of the substance 1-(6-Fluorobenzothiazol-2-yl)ethanol 1-(6-fluoro-1,3-benzothiazol-2-yl)ethanol Not in list C9H8FNOS CC(O)c1nc2ccc(F)cc2s1 InChI=1/C9H8FNOS/c1-5(12)9-11-7-3-2-6(10)4-8(7)13-9/h2-5,12H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is a metabolite of the substance 1-(6-Fluorobenzothiazol-2-yl)ethanol 1-(6-fluoro-1,3-benzothiazol-2-yl)ethanol Not in list C9H8FNOS CC(O)c1nc2ccc(F)cc2s1 InChI=1/C9H8FNOS/c1-5(12)9-11-7-3-2-6(10)4-8(7)13-9/h2-5,12H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is a metabolite of the substance 1-(6-Fluorobenzothiazol-2-yl)ethanol 1-(6-fluoro-1,3-benzothiazol-2-yl)ethanol Not in list C9H8FNOS CC(O)c1nc2ccc(F)cc2s1 InChI=1/C9H8FNOS/c1-5(12)9-11-7-3-2-6(10)4-8(7)13-9/h2-5,12H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is a metabolite of the substance 1-(6-Fluorobenzothiazol-2-yl)ethanol 1-(6-fluoro-1,3-benzothiazol-2-yl)ethanol Not in list C9H8FNOS CC(O)c1nc2ccc(F)cc2s1 InChI=1/C9H8FNOS/c1-5(12)9-11-7-3-2-6(10)4-8(7)13-9/h2-5,12H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is a metabolite of the substance 1-(6-Fluorobenzothiazol-2-yl)ethanol 1-(6-fluoro-1,3-benzothiazol-2-yl)ethanol Not in list C9H8FNOS CC(O)c1nc2ccc(F)cc2s1 InChI=1/C9H8FNOS/c1-5(12)9-11-7-3-2-6(10)4-8(7)13-9/h2-5,12H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is a metabolite of the substance Isopropyl (1S)-1-[(1R or S)-1-(6-fluoro-5-hydroxybenzothiazol-2-yl)ethylcarbamoyl]-2-methylpropylcarbamate Isopropyl (1S)-1-[(1R or S)-1-(6-fluoro-5-hydroxybenzothiazol-2-yl)ethylcarbamoyl]-2-methylpropylcarbamate Not in list C18H24FN3O4S CC(C)C(NC(=O)OC(C)C)C(=O)NC(C)c1nc2cc(O)c(F)cc2s1 InChI=1/C18H24FN3O4S/c1-8(2)15(22-18(25)26-9(3)4)16(24)20-10(5)17-21-12-7-13(23)11(19)6-14(12)27-17/h6-10,15,23H,1-5H3,(H,20,24)(H,22,25) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is a metabolite of the substance Isopropyl (1S)-1-[(1R or S)-1-(6-fluoro-5-hydroxybenzothiazol-2-yl)ethylcarbamoyl]-2-methylpropylcarbamate Isopropyl (1S)-1-[(1R or S)-1-(6-fluoro-5-hydroxybenzothiazol-2-yl)ethylcarbamoyl]-2-methylpropylcarbamate Not in list C18H24FN3O4S CC(C)C(NC(=O)OC(C)C)C(=O)NC(C)c1nc2cc(O)c(F)cc2s1 InChI=1/C18H24FN3O4S/c1-8(2)15(22-18(25)26-9(3)4)16(24)20-10(5)17-21-12-7-13(23)11(19)6-14(12)27-17/h6-10,15,23H,1-5H3,(H,20,24)(H,22,25) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is a metabolite of the substance Isopropyl (1S)-1-[(1R or S)-1-(6-fluoro-5-hydroxybenzothiazol-2-yl)ethylcarbamoyl]-2-methylpropylcarbamate Isopropyl (1S)-1-[(1R or S)-1-(6-fluoro-5-hydroxybenzothiazol-2-yl)ethylcarbamoyl]-2-methylpropylcarbamate Not in list C18H24FN3O4S CC(C)C(NC(=O)OC(C)C)C(=O)NC(C)c1nc2cc(O)c(F)cc2s1 InChI=1/C18H24FN3O4S/c1-8(2)15(22-18(25)26-9(3)4)16(24)20-10(5)17-21-12-7-13(23)11(19)6-14(12)27-17/h6-10,15,23H,1-5H3,(H,20,24)(H,22,25) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is a metabolite of the substance Isopropyl (1S)-1-[(1R or S)-1-(6-fluoro-5-hydroxybenzothiazol-2-yl)ethylcarbamoyl]-2-methylpropylcarbamate Isopropyl (1S)-1-[(1R or S)-1-(6-fluoro-5-hydroxybenzothiazol-2-yl)ethylcarbamoyl]-2-methylpropylcarbamate Not in list C18H24FN3O4S CC(C)C(NC(=O)OC(C)C)C(=O)NC(C)c1nc2cc(O)c(F)cc2s1 InChI=1/C18H24FN3O4S/c1-8(2)15(22-18(25)26-9(3)4)16(24)20-10(5)17-21-12-7-13(23)11(19)6-14(12)27-17/h6-10,15,23H,1-5H3,(H,20,24)(H,22,25) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is a metabolite of the substance Isopropyl (1S)-1-[(1R or S)-1-(6-fluoro-5-hydroxybenzothiazol-2-yl)ethylcarbamoyl]-2-methylpropylcarbamate Isopropyl (1S)-1-[(1R or S)-1-(6-fluoro-5-hydroxybenzothiazol-2-yl)ethylcarbamoyl]-2-methylpropylcarbamate Not in list C18H24FN3O4S CC(C)C(NC(=O)OC(C)C)C(=O)NC(C)c1nc2cc(O)c(F)cc2s1 InChI=1/C18H24FN3O4S/c1-8(2)15(22-18(25)26-9(3)4)16(24)20-10(5)17-21-12-7-13(23)11(19)6-14(12)27-17/h6-10,15,23H,1-5H3,(H,20,24)(H,22,25) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is a metabolite of the substance Isopropyl (1S)-1-[(1R or S)-1-(6-fluoro-5-hydroxybenzothiazol-2-yl)ethylcarbamoyl]-2-methylpropylcarbamate Isopropyl (1S)-1-[(1R or S)-1-(6-fluoro-5-hydroxybenzothiazol-2-yl)ethylcarbamoyl]-2-methylpropylcarbamate Not in list C18H24FN3O4S CC(C)C(NC(=O)OC(C)C)C(=O)NC(C)c1nc2cc(O)c(F)cc2s1 InChI=1/C18H24FN3O4S/c1-8(2)15(22-18(25)26-9(3)4)16(24)20-10(5)17-21-12-7-13(23)11(19)6-14(12)27-17/h6-10,15,23H,1-5H3,(H,20,24)(H,22,25) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is a metabolite of the substance Isopropyl (1S)-1-[(1R or S)-1-(6-fluoro-5-hydroxybenzothiazol-2-yl)ethylcarbamoyl]-2-methylpropylcarbamate Isopropyl (1S)-1-[(1R or S)-1-(6-fluoro-5-hydroxybenzothiazol-2-yl)ethylcarbamoyl]-2-methylpropylcarbamate Not in list C18H24FN3O4S CC(C)C(NC(=O)OC(C)C)C(=O)NC(C)c1nc2cc(O)c(F)cc2s1 InChI=1/C18H24FN3O4S/c1-8(2)15(22-18(25)26-9(3)4)16(24)20-10(5)17-21-12-7-13(23)11(19)6-14(12)27-17/h6-10,15,23H,1-5H3,(H,20,24)(H,22,25) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is a metabolite of the substance Isopropyl (1S)-1-[(1R or S)-1-(6-fluoro-5-hydroxybenzothiazol-2-yl)ethylcarbamoyl]-2-methylpropylcarbamate Isopropyl (1S)-1-[(1R or S)-1-(6-fluoro-5-hydroxybenzothiazol-2-yl)ethylcarbamoyl]-2-methylpropylcarbamate Not in list C18H24FN3O4S CC(C)C(NC(=O)OC(C)C)C(=O)NC(C)c1nc2cc(O)c(F)cc2s1 InChI=1/C18H24FN3O4S/c1-8(2)15(22-18(25)26-9(3)4)16(24)20-10(5)17-21-12-7-13(23)11(19)6-14(12)27-17/h6-10,15,23H,1-5H3,(H,20,24)(H,22,25) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is a metabolite of the substance Isopropyl (1S)-1-[(1R or S)-1-(6-fluoro-5-hydroxybenzothiazol-2-yl)ethylcarbamoyl]-2-methylpropylcarbamate Isopropyl (1S)-1-[(1R or S)-1-(6-fluoro-5-hydroxybenzothiazol-2-yl)ethylcarbamoyl]-2-methylpropylcarbamate Not in list C18H24FN3O4S CC(C)C(NC(=O)OC(C)C)C(=O)NC(C)c1nc2cc(O)c(F)cc2s1 InChI=1/C18H24FN3O4S/c1-8(2)15(22-18(25)26-9(3)4)16(24)20-10(5)17-21-12-7-13(23)11(19)6-14(12)27-17/h6-10,15,23H,1-5H3,(H,20,24)(H,22,25) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is a metabolite of the substance Isopropyl (1S)-1-[(1R or S)-1-(6-fluoro-5-hydroxybenzothiazol-2-yl)ethylcarbamoyl]-2-methylpropylcarbamate Isopropyl (1S)-1-[(1R or S)-1-(6-fluoro-5-hydroxybenzothiazol-2-yl)ethylcarbamoyl]-2-methylpropylcarbamate Not in list C18H24FN3O4S CC(C)C(NC(=O)OC(C)C)C(=O)NC(C)c1nc2cc(O)c(F)cc2s1 InChI=1/C18H24FN3O4S/c1-8(2)15(22-18(25)26-9(3)4)16(24)20-10(5)17-21-12-7-13(23)11(19)6-14(12)27-17/h6-10,15,23H,1-5H3,(H,20,24)(H,22,25) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Clodinafop-propargyl 105512-06-9 single chemical entity Component is identical to the substance Clodinafop-propargyl 105512-06-9 prop-2-yn-1-yl (2R)-2-{4-[(5-chloro-3-fluoropyridin-2-yl)oxy]phenoxy}propanoate Clodinafop-Propargyl C17H13ClFNO4 O=C(OCC#C)[C@H](OC1=CC=C(OC2=NC=C(Cl)C=C2F)C=C1)C InChI=1S/C17H13ClFNO4/c1-3-8-22-17(21)11(2)23-13-4-6-14(7-5-13)24-16-15(19)9-12(18)10-20-16/h1,4-7,9-11H,8H2,2H3/t11-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The Netherlands Clodinafop-propargyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clodinafop 31Aug2005 2005 doi:10.2903/j.efsa.2005.34ar
+Clodinafop-propargyl 105512-06-9 single chemical entity Component is identical to the substance Clodinafop-propargyl 105512-06-9 prop-2-yn-1-yl (2R)-2-{4-[(5-chloro-3-fluoropyridin-2-yl)oxy]phenoxy}propanoate Clodinafop-Propargyl C17H13ClFNO4 O=C(OCC#C)[C@H](OC1=CC=C(OC2=NC=C(Cl)C=C2F)C=C1)C InChI=1S/C17H13ClFNO4/c1-3-8-22-17(21)11(2)23-13-4-6-14(7-5-13)24-16-15(19)9-12(18)10-20-16/h1,4-7,9-11H,8H2,2H3/t11-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The Netherlands Clodinafop-propargyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clodinafop 31Aug2005 2005 doi:10.2903/j.efsa.2005.34ar
+Clodinafop-propargyl 105512-06-9 single chemical entity Component is identical to the substance Clodinafop-propargyl 105512-06-9 prop-2-yn-1-yl (2R)-2-{4-[(5-chloro-3-fluoropyridin-2-yl)oxy]phenoxy}propanoate Clodinafop-Propargyl C17H13ClFNO4 O=C(OCC#C)[C@H](OC1=CC=C(OC2=NC=C(Cl)C=C2F)C=C1)C InChI=1S/C17H13ClFNO4/c1-3-8-22-17(21)11(2)23-13-4-6-14(7-5-13)24-16-15(19)9-12(18)10-20-16/h1,4-7,9-11H,8H2,2H3/t11-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The Netherlands Clodinafop-propargyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clodinafop 31Aug2005 2005 doi:10.2903/j.efsa.2005.34ar
+Clodinafop-propargyl 105512-06-9 single chemical entity Component is identical to the substance Clodinafop-propargyl 105512-06-9 prop-2-yn-1-yl (2R)-2-{4-[(5-chloro-3-fluoropyridin-2-yl)oxy]phenoxy}propanoate Clodinafop-Propargyl C17H13ClFNO4 O=C(OCC#C)[C@H](OC1=CC=C(OC2=NC=C(Cl)C=C2F)C=C1)C InChI=1S/C17H13ClFNO4/c1-3-8-22-17(21)11(2)23-13-4-6-14(7-5-13)24-16-15(19)9-12(18)10-20-16/h1,4-7,9-11H,8H2,2H3/t11-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The Netherlands Clodinafop-propargyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clodinafop 31Aug2005 2005 doi:10.2903/j.efsa.2005.34ar
+Clodinafop-propargyl 105512-06-9 single chemical entity Component is identical to the substance Clodinafop-propargyl 105512-06-9 prop-2-yn-1-yl (2R)-2-{4-[(5-chloro-3-fluoropyridin-2-yl)oxy]phenoxy}propanoate Clodinafop-Propargyl C17H13ClFNO4 O=C(OCC#C)[C@H](OC1=CC=C(OC2=NC=C(Cl)C=C2F)C=C1)C InChI=1S/C17H13ClFNO4/c1-3-8-22-17(21)11(2)23-13-4-6-14(7-5-13)24-16-15(19)9-12(18)10-20-16/h1,4-7,9-11H,8H2,2H3/t11-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The Netherlands Clodinafop-propargyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clodinafop 31Aug2005 2005 doi:10.2903/j.efsa.2005.34ar
+Clodinafop-propargyl 105512-06-9 single chemical entity Component is identical to the substance Clodinafop-propargyl 105512-06-9 prop-2-yn-1-yl (2R)-2-{4-[(5-chloro-3-fluoropyridin-2-yl)oxy]phenoxy}propanoate Clodinafop-Propargyl C17H13ClFNO4 O=C(OCC#C)[C@H](OC1=CC=C(OC2=NC=C(Cl)C=C2F)C=C1)C InChI=1S/C17H13ClFNO4/c1-3-8-22-17(21)11(2)23-13-4-6-14(7-5-13)24-16-15(19)9-12(18)10-20-16/h1,4-7,9-11H,8H2,2H3/t11-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The Netherlands Clodinafop-propargyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clodinafop 31Aug2005 2005 doi:10.2903/j.efsa.2005.34ar
+Clodinafop-propargyl 105512-06-9 single chemical entity Component is identical to the substance Clodinafop-propargyl 105512-06-9 prop-2-yn-1-yl (2R)-2-{4-[(5-chloro-3-fluoropyridin-2-yl)oxy]phenoxy}propanoate Clodinafop-Propargyl C17H13ClFNO4 O=C(OCC#C)[C@H](OC1=CC=C(OC2=NC=C(Cl)C=C2F)C=C1)C InChI=1S/C17H13ClFNO4/c1-3-8-22-17(21)11(2)23-13-4-6-14(7-5-13)24-16-15(19)9-12(18)10-20-16/h1,4-7,9-11H,8H2,2H3/t11-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The Netherlands Clodinafop-propargyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clodinafop 31Aug2005 2005 doi:10.2903/j.efsa.2005.34ar
+Clodinafop-propargyl 105512-06-9 single chemical entity Component is identical to the substance Clodinafop-propargyl 105512-06-9 prop-2-yn-1-yl (2R)-2-{4-[(5-chloro-3-fluoropyridin-2-yl)oxy]phenoxy}propanoate Clodinafop-Propargyl C17H13ClFNO4 O=C(OCC#C)[C@H](OC1=CC=C(OC2=NC=C(Cl)C=C2F)C=C1)C InChI=1S/C17H13ClFNO4/c1-3-8-22-17(21)11(2)23-13-4-6-14(7-5-13)24-16-15(19)9-12(18)10-20-16/h1,4-7,9-11H,8H2,2H3/t11-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The Netherlands Clodinafop-propargyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clodinafop 31Aug2005 2005 doi:10.2903/j.efsa.2005.34ar
+Clodinafop-propargyl 105512-06-9 single chemical entity Component is identical to the substance Clodinafop-propargyl 105512-06-9 prop-2-yn-1-yl (2R)-2-{4-[(5-chloro-3-fluoropyridin-2-yl)oxy]phenoxy}propanoate Clodinafop-Propargyl C17H13ClFNO4 O=C(OCC#C)[C@H](OC1=CC=C(OC2=NC=C(Cl)C=C2F)C=C1)C InChI=1S/C17H13ClFNO4/c1-3-8-22-17(21)11(2)23-13-4-6-14(7-5-13)24-16-15(19)9-12(18)10-20-16/h1,4-7,9-11H,8H2,2H3/t11-/m1/s1 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Negative RMS: The Netherlands Clodinafop-propargyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clodinafop 31Aug2005 2005 doi:10.2903/j.efsa.2005.34ar
+Clodinafop-propargyl 105512-06-9 single chemical entity Component is identical to the substance Clodinafop-propargyl 105512-06-9 prop-2-yn-1-yl (2R)-2-{4-[(5-chloro-3-fluoropyridin-2-yl)oxy]phenoxy}propanoate Clodinafop-Propargyl C17H13ClFNO4 O=C(OCC#C)[C@H](OC1=CC=C(OC2=NC=C(Cl)C=C2F)C=C1)C InChI=1S/C17H13ClFNO4/c1-3-8-22-17(21)11(2)23-13-4-6-14(7-5-13)24-16-15(19)9-12(18)10-20-16/h1,4-7,9-11H,8H2,2H3/t11-/m1/s1 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: The Netherlands Clodinafop-propargyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clodinafop 31Aug2005 2005 doi:10.2903/j.efsa.2005.34ar
+Clodinafop-propargyl 105512-06-9 single chemical entity Component is identical to the substance Clodinafop-propargyl 105512-06-9 prop-2-yn-1-yl (2R)-2-{4-[(5-chloro-3-fluoropyridin-2-yl)oxy]phenoxy}propanoate Clodinafop-Propargyl C17H13ClFNO4 O=C(OCC#C)[C@H](OC1=CC=C(OC2=NC=C(Cl)C=C2F)C=C1)C InChI=1S/C17H13ClFNO4/c1-3-8-22-17(21)11(2)23-13-4-6-14(7-5-13)24-16-15(19)9-12(18)10-20-16/h1,4-7,9-11H,8H2,2H3/t11-/m1/s1 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes with Negative RMS: The Netherlands Clodinafop-propargyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clodinafop 31Aug2005 2005 doi:10.2903/j.efsa.2005.34ar
+Clodinafop-propargyl 105512-06-9 single chemical entity Component is identical to the substance Clodinafop-propargyl 105512-06-9 prop-2-yn-1-yl (2R)-2-{4-[(5-chloro-3-fluoropyridin-2-yl)oxy]phenoxy}propanoate Clodinafop-Propargyl C17H13ClFNO4 O=C(OCC#C)[C@H](OC1=CC=C(OC2=NC=C(Cl)C=C2F)C=C1)C InChI=1S/C17H13ClFNO4/c1-3-8-22-17(21)11(2)23-13-4-6-14(7-5-13)24-16-15(19)9-12(18)10-20-16/h1,4-7,9-11H,8H2,2H3/t11-/m1/s1 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes without Negative RMS: The Netherlands Clodinafop-propargyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clodinafop 31Aug2005 2005 doi:10.2903/j.efsa.2005.34ar
+Clodinafop-propargyl 105512-06-9 single chemical entity Component is identical to the substance Clodinafop-propargyl 105512-06-9 prop-2-yn-1-yl (2R)-2-{4-[(5-chloro-3-fluoropyridin-2-yl)oxy]phenoxy}propanoate Clodinafop-Propargyl C17H13ClFNO4 O=C(OCC#C)[C@H](OC1=CC=C(OC2=NC=C(Cl)C=C2F)C=C1)C InChI=1S/C17H13ClFNO4/c1-3-8-22-17(21)11(2)23-13-4-6-14(7-5-13)24-16-15(19)9-12(18)10-20-16/h1,4-7,9-11H,8H2,2H3/t11-/m1/s1 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: The Netherlands Clodinafop-propargyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clodinafop 31Aug2005 2005 doi:10.2903/j.efsa.2005.34ar
+Clodinafop-propargyl 105512-06-9 single chemical entity Component is identical to the substance Clodinafop-propargyl 105512-06-9 prop-2-yn-1-yl (2R)-2-{4-[(5-chloro-3-fluoropyridin-2-yl)oxy]phenoxy}propanoate Clodinafop-Propargyl C17H13ClFNO4 O=C(OCC#C)[C@H](OC1=CC=C(OC2=NC=C(Cl)C=C2F)C=C1)C InChI=1S/C17H13ClFNO4/c1-3-8-22-17(21)11(2)23-13-4-6-14(7-5-13)24-16-15(19)9-12(18)10-20-16/h1,4-7,9-11H,8H2,2H3/t11-/m1/s1 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: The Netherlands Clodinafop-propargyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clodinafop 31Aug2005 2005 doi:10.2903/j.efsa.2005.34ar
+Clodinafop-propargyl 105512-06-9 single chemical entity Component is identical to the substance Clodinafop-propargyl 105512-06-9 prop-2-yn-1-yl (2R)-2-{4-[(5-chloro-3-fluoropyridin-2-yl)oxy]phenoxy}propanoate Clodinafop-Propargyl C17H13ClFNO4 O=C(OCC#C)[C@H](OC1=CC=C(OC2=NC=C(Cl)C=C2F)C=C1)C InChI=1S/C17H13ClFNO4/c1-3-8-22-17(21)11(2)23-13-4-6-14(7-5-13)24-16-15(19)9-12(18)10-20-16/h1,4-7,9-11H,8H2,2H3/t11-/m1/s1 organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo Equivalent or similar to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) Yes Acceptable Rat (as animal) Wistar 4 Male oral: gavage 16.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The Netherlands Clodinafop-propargyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clodinafop 31Aug2005 2005 doi:10.2903/j.efsa.2005.34ar
+Clodinafop-propargyl 105512-06-9 single chemical entity Component is identical to the substance Clodinafop-propargyl 105512-06-9 prop-2-yn-1-yl (2R)-2-{4-[(5-chloro-3-fluoropyridin-2-yl)oxy]phenoxy}propanoate Clodinafop-Propargyl C17H13ClFNO4 O=C(OCC#C)[C@H](OC1=CC=C(OC2=NC=C(Cl)C=C2F)C=C1)C InChI=1S/C17H13ClFNO4/c1-3-8-22-17(21)11(2)23-13-4-6-14(7-5-13)24-16-15(19)9-12(18)10-20-16/h1,4-7,9-11H,8H2,2H3/t11-/m1/s1 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Not reported 48 Male/Female oral: gavage 48.0000000000 h yes not applicable Negative indirect evidence-systemic toxicity RMS: The Netherlands Clodinafop-propargyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clodinafop 31Aug2005 2005 doi:10.2903/j.efsa.2005.34ar
+Clodinafop-propargyl 105512-06-9 single chemical entity Component is identical to the substance Clodinafop-propargyl 105512-06-9 prop-2-yn-1-yl (2R)-2-{4-[(5-chloro-3-fluoropyridin-2-yl)oxy]phenoxy}propanoate Clodinafop-Propargyl C17H13ClFNO4 O=C(OCC#C)[C@H](OC1=CC=C(OC2=NC=C(Cl)C=C2F)C=C1)C InChI=1S/C17H13ClFNO4/c1-3-8-22-17(21)11(2)23-13-4-6-14(7-5-13)24-16-15(19)9-12(18)10-20-16/h1,4-7,9-11H,8H2,2H3/t11-/m1/s1 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Not reported 48 Male/Female oral: gavage 24.0000000000 h yes not applicable Negative indirect evidence-systemic toxicity RMS: The Netherlands Clodinafop-propargyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clodinafop 31Aug2005 2005 doi:10.2903/j.efsa.2005.34ar
+Clodinafop-propargyl 105512-06-9 single chemical entity Component is identical to the substance Clodinafop-propargyl 105512-06-9 prop-2-yn-1-yl (2R)-2-{4-[(5-chloro-3-fluoropyridin-2-yl)oxy]phenoxy}propanoate Clodinafop-Propargyl C17H13ClFNO4 O=C(OCC#C)[C@H](OC1=CC=C(OC2=NC=C(Cl)C=C2F)C=C1)C InChI=1S/C17H13ClFNO4/c1-3-8-22-17(21)11(2)23-13-4-6-14(7-5-13)24-16-15(19)9-12(18)10-20-16/h1,4-7,9-11H,8H2,2H3/t11-/m1/s1 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Not reported 48 Male/Female oral: gavage 72.0000000000 h yes not applicable Negative indirect evidence-systemic toxicity RMS: The Netherlands Clodinafop-propargyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clodinafop 31Aug2005 2005 doi:10.2903/j.efsa.2005.34ar
+Clomazone 81777-89-1 single chemical entity Component is identical to the substance Clomazone 81777-89-1 2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one Clomazone C12H14ClNO2 O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Denmark Clomazone 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone 17Aug2007 2007 doi:10.2903/j.efsa.2007.109r
+Clomazone 81777-89-1 single chemical entity Component is identical to the substance Clomazone 81777-89-1 2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one Clomazone C12H14ClNO2 O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Denmark Clomazone 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone 17Aug2007 2007 doi:10.2903/j.efsa.2007.109r
+Clomazone 81777-89-1 single chemical entity Component is identical to the substance Clomazone 81777-89-1 2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one Clomazone C12H14ClNO2 O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Denmark Clomazone 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone 17Aug2007 2007 doi:10.2903/j.efsa.2007.109r
+Clomazone 81777-89-1 single chemical entity Component is identical to the substance Clomazone 81777-89-1 2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one Clomazone C12H14ClNO2 O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Denmark Clomazone 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone 17Aug2007 2007 doi:10.2903/j.efsa.2007.109r
+Clomazone 81777-89-1 single chemical entity Component is identical to the substance Clomazone 81777-89-1 2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one Clomazone C12H14ClNO2 O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Denmark Clomazone 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone 17Aug2007 2007 doi:10.2903/j.efsa.2007.109r
+Clomazone 81777-89-1 single chemical entity Component is identical to the substance Clomazone 81777-89-1 2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one Clomazone C12H14ClNO2 O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Denmark Clomazone 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone 17Aug2007 2007 doi:10.2903/j.efsa.2007.109r
+Clomazone 81777-89-1 single chemical entity Component is identical to the substance Clomazone 81777-89-1 2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one Clomazone C12H14ClNO2 O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Denmark Clomazone 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone 17Aug2007 2007 doi:10.2903/j.efsa.2007.109r
+Clomazone 81777-89-1 single chemical entity Component is identical to the substance Clomazone 81777-89-1 2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one Clomazone C12H14ClNO2 O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Denmark Clomazone 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone 17Aug2007 2007 doi:10.2903/j.efsa.2007.109r
+Clomazone 81777-89-1 single chemical entity Component is identical to the substance Clomazone 81777-89-1 2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one Clomazone C12H14ClNO2 O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Denmark Clomazone 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone 17Aug2007 2007 doi:10.2903/j.efsa.2007.109r
+Clomazone 81777-89-1 single chemical entity Component is identical to the substance Clomazone 81777-89-1 2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one Clomazone C12H14ClNO2 O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Denmark Clomazone 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone 17Aug2007 2007 doi:10.2903/j.efsa.2007.109r
+Clomazone 81777-89-1 single chemical entity Component is identical to the substance Clomazone 81777-89-1 2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one Clomazone C12H14ClNO2 O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Denmark Clomazone 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone 17Aug2007 2007 doi:10.2903/j.efsa.2007.109r
+Clomazone 81777-89-1 single chemical entity Component is identical to the substance Clomazone 81777-89-1 2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one Clomazone C12H14ClNO2 O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Denmark Clomazone 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone 17Aug2007 2007 doi:10.2903/j.efsa.2007.109r
+Clomazone 81777-89-1 single chemical entity Component is identical to the substance Clomazone 81777-89-1 2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one Clomazone C12H14ClNO2 O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Denmark Clomazone 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone 17Aug2007 2007 doi:10.2903/j.efsa.2007.109r
+Clomazone 81777-89-1 single chemical entity Component is identical to the substance Clomazone 81777-89-1 2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one Clomazone C12H14ClNO2 O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Denmark Clomazone 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone 17Aug2007 2007 doi:10.2903/j.efsa.2007.109r
+Clomazone 81777-89-1 single chemical entity Component is identical to the substance Clomazone 81777-89-1 2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one Clomazone C12H14ClNO2 O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Denmark Clomazone 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone 17Aug2007 2007 doi:10.2903/j.efsa.2007.109r
+Clomazone 81777-89-1 single chemical entity Component is identical to the substance Clomazone 81777-89-1 2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one Clomazone C12H14ClNO2 O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Denmark Clomazone 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone 17Aug2007 2007 doi:10.2903/j.efsa.2007.109r
+Clomazone 81777-89-1 single chemical entity Component is identical to the substance Clomazone 81777-89-1 2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one Clomazone C12H14ClNO2 O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Denmark Clomazone 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone 17Aug2007 2007 doi:10.2903/j.efsa.2007.109r
+Clomazone 81777-89-1 single chemical entity Component is identical to the substance Clomazone 81777-89-1 2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one Clomazone C12H14ClNO2 O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Denmark Clomazone 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone 17Aug2007 2007 doi:10.2903/j.efsa.2007.109r
+Clomazone 81777-89-1 single chemical entity Component is identical to the substance Clomazone 81777-89-1 2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one Clomazone C12H14ClNO2 O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Denmark Clomazone 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone 17Aug2007 2007 doi:10.2903/j.efsa.2007.109r
+Clomazone 81777-89-1 single chemical entity Component is identical to the substance Clomazone 81777-89-1 2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one Clomazone C12H14ClNO2 O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Denmark Clomazone 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone 17Aug2007 2007 doi:10.2903/j.efsa.2007.109r
+Clomazone 81777-89-1 single chemical entity Component is identical to the substance Clomazone 81777-89-1 2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one Clomazone C12H14ClNO2 O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Denmark Clomazone 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone 17Aug2007 2007 doi:10.2903/j.efsa.2007.109r
+Clomazone 81777-89-1 single chemical entity Component is identical to the substance Clomazone 81777-89-1 2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one Clomazone C12H14ClNO2 O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Denmark Clomazone 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone 17Aug2007 2007 doi:10.2903/j.efsa.2007.109r
+Clomazone 81777-89-1 single chemical entity Component is identical to the substance Clomazone 81777-89-1 2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one Clomazone C12H14ClNO2 O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Denmark Clomazone 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone 17Aug2007 2007 doi:10.2903/j.efsa.2007.109r
+Clomazone 81777-89-1 single chemical entity Component is identical to the substance Clomazone 81777-89-1 2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one Clomazone C12H14ClNO2 O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Denmark Clomazone 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone 17Aug2007 2007 doi:10.2903/j.efsa.2007.109r
+Clomazone 81777-89-1 single chemical entity Component is identical to the substance Clomazone 81777-89-1 2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one Clomazone C12H14ClNO2 O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Denmark Clomazone 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone 17Aug2007 2007 doi:10.2903/j.efsa.2007.109r
+Clomazone 81777-89-1 single chemical entity Component is identical to the substance Clomazone 81777-89-1 2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one Clomazone C12H14ClNO2 O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Denmark Clomazone 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone 17Aug2007 2007 doi:10.2903/j.efsa.2007.109r
+Clomazone 81777-89-1 single chemical entity Component is identical to the substance Clomazone 81777-89-1 2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one Clomazone C12H14ClNO2 O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Denmark Clomazone 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone 17Aug2007 2007 doi:10.2903/j.efsa.2007.109r
+Clomazone 81777-89-1 single chemical entity Component is identical to the substance Clomazone 81777-89-1 2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one Clomazone C12H14ClNO2 O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Denmark Clomazone 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone 17Aug2007 2007 doi:10.2903/j.efsa.2007.109r
+Clomazone 81777-89-1 single chemical entity Component is identical to the substance Clomazone 81777-89-1 2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one Clomazone C12H14ClNO2 O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Denmark Clomazone 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone 17Aug2007 2007 doi:10.2903/j.efsa.2007.109r
+Clomazone 81777-89-1 single chemical entity Component is identical to the substance Clomazone 81777-89-1 2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one Clomazone C12H14ClNO2 O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Denmark Clomazone 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone 17Aug2007 2007 doi:10.2903/j.efsa.2007.109r
+Clomazone 81777-89-1 single chemical entity Component is identical to the substance Clomazone 81777-89-1 2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one Clomazone C12H14ClNO2 O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: Denmark Clomazone 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone 17Aug2007 2007 doi:10.2903/j.efsa.2007.109r
+Clomazone 81777-89-1 single chemical entity Component is identical to the substance Clomazone 81777-89-1 2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one Clomazone C12H14ClNO2 O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: Denmark Clomazone 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone 17Aug2007 2007 doi:10.2903/j.efsa.2007.109r
+Clomazone 81777-89-1 single chemical entity Component is identical to the substance Clomazone 81777-89-1 2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one Clomazone C12H14ClNO2 O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3 organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Rat (as animal) hepatocytes Not reported yes without Negative RMS: Denmark Clomazone 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone 17Aug2007 2007 doi:10.2903/j.efsa.2007.109r
+Clomazone 81777-89-1 single chemical entity Component is identical to the substance Clomazone 81777-89-1 2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one Clomazone C12H14ClNO2 O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3 organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Rat (as animal) hepatocytes Not reported yes with Negative RMS: Denmark Clomazone 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone 17Aug2007 2007 doi:10.2903/j.efsa.2007.109r
+Clomazone 81777-89-1 single chemical entity Component is identical to the substance Clomazone 81777-89-1 2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one Clomazone C12H14ClNO2 O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable Rat (as animal) Sprague-Dawley 5 Male oral: gavage 6.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Denmark Clomazone 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone 17Aug2007 2007 doi:10.2903/j.efsa.2007.109r
+Clomazone 81777-89-1 single chemical entity Component is a metabolite of the substance Isoxazolidine 81778-07-6 4,4-dimethyl-1,2-oxazolidin-3-one Not in list C5H9NO2 CC1(CONC1=O)C InChI=1S/C5H9NO2/c1-5(2)3-8-6-4(5)7/h3H2,1-2H3,(H,6,7) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Denmark Clomazone 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone 17Aug2007 2007 doi:10.2903/j.efsa.2007.109r
+Clomazone 81777-89-1 single chemical entity Component is a metabolite of the substance Isoxazolidine 81778-07-6 4,4-dimethyl-1,2-oxazolidin-3-one Not in list C5H9NO2 CC1(CONC1=O)C InChI=1S/C5H9NO2/c1-5(2)3-8-6-4(5)7/h3H2,1-2H3,(H,6,7) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Denmark Clomazone 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone 17Aug2007 2007 doi:10.2903/j.efsa.2007.109r
+Clomazone 81777-89-1 single chemical entity Component is a metabolite of the substance Isoxazolidine 81778-07-6 4,4-dimethyl-1,2-oxazolidin-3-one Not in list C5H9NO2 CC1(CONC1=O)C InChI=1S/C5H9NO2/c1-5(2)3-8-6-4(5)7/h3H2,1-2H3,(H,6,7) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Denmark Clomazone 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone 17Aug2007 2007 doi:10.2903/j.efsa.2007.109r
+Clomazone 81777-89-1 single chemical entity Component is a metabolite of the substance Isoxazolidine 81778-07-6 4,4-dimethyl-1,2-oxazolidin-3-one Not in list C5H9NO2 CC1(CONC1=O)C InChI=1S/C5H9NO2/c1-5(2)3-8-6-4(5)7/h3H2,1-2H3,(H,6,7) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Denmark Clomazone 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone 17Aug2007 2007 doi:10.2903/j.efsa.2007.109r
+Clomazone 81777-89-1 single chemical entity Component is a metabolite of the substance Isoxazolidine 81778-07-6 4,4-dimethyl-1,2-oxazolidin-3-one Not in list C5H9NO2 CC1(CONC1=O)C InChI=1S/C5H9NO2/c1-5(2)3-8-6-4(5)7/h3H2,1-2H3,(H,6,7) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Denmark Clomazone 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone 17Aug2007 2007 doi:10.2903/j.efsa.2007.109r
+Clomazone 81777-89-1 single chemical entity Component is a metabolite of the substance Isoxazolidine 81778-07-6 4,4-dimethyl-1,2-oxazolidin-3-one Not in list C5H9NO2 CC1(CONC1=O)C InChI=1S/C5H9NO2/c1-5(2)3-8-6-4(5)7/h3H2,1-2H3,(H,6,7) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Denmark Clomazone 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone 17Aug2007 2007 doi:10.2903/j.efsa.2007.109r
+Clomazone 81777-89-1 single chemical entity Component is a metabolite of the substance Isoxazolidine 81778-07-6 4,4-dimethyl-1,2-oxazolidin-3-one Not in list C5H9NO2 CC1(CONC1=O)C InChI=1S/C5H9NO2/c1-5(2)3-8-6-4(5)7/h3H2,1-2H3,(H,6,7) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Denmark Clomazone 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone 17Aug2007 2007 doi:10.2903/j.efsa.2007.109r
+Clomazone 81777-89-1 single chemical entity Component is a metabolite of the substance Isoxazolidine 81778-07-6 4,4-dimethyl-1,2-oxazolidin-3-one Not in list C5H9NO2 CC1(CONC1=O)C InChI=1S/C5H9NO2/c1-5(2)3-8-6-4(5)7/h3H2,1-2H3,(H,6,7) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Denmark Clomazone 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone 17Aug2007 2007 doi:10.2903/j.efsa.2007.109r
+Clomazone 81777-89-1 single chemical entity Component is a metabolite of the substance Isoxazolidine 81778-07-6 4,4-dimethyl-1,2-oxazolidin-3-one Not in list C5H9NO2 CC1(CONC1=O)C InChI=1S/C5H9NO2/c1-5(2)3-8-6-4(5)7/h3H2,1-2H3,(H,6,7) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Denmark Clomazone 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone 17Aug2007 2007 doi:10.2903/j.efsa.2007.109r
+Clomazone 81777-89-1 single chemical entity Component is a metabolite of the substance Isoxazolidine 81778-07-6 4,4-dimethyl-1,2-oxazolidin-3-one Not in list C5H9NO2 CC1(CONC1=O)C InChI=1S/C5H9NO2/c1-5(2)3-8-6-4(5)7/h3H2,1-2H3,(H,6,7) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Denmark Clomazone 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone 17Aug2007 2007 doi:10.2903/j.efsa.2007.109r
+Diclofop-methyl 257-141-8 51338-27-3 single chemical entity Component is identical to the substance Diclofop-methyl 257-141-8 51338-27-3 Methyl 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoate Diclofop-Methyl C16H14Cl2O4 CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)Cl)Cl InChI=1S/C16H14Cl2O4/c1-10(16(19)20-2)21-12-4-6-13(7-5-12)22-15-8-3-11(17)9-14(15)18/h3-10H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: France Diclofop-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diclofop (considered variant diclofop-methyl) 07Oct2010 2010 doi:10.2903/j.efsa.2010.1718
+Diclofop-methyl 257-141-8 51338-27-3 single chemical entity Component is identical to the substance Diclofop-methyl 257-141-8 51338-27-3 Methyl 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoate Diclofop-Methyl C16H14Cl2O4 CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)Cl)Cl InChI=1S/C16H14Cl2O4/c1-10(16(19)20-2)21-12-4-6-13(7-5-12)22-15-8-3-11(17)9-14(15)18/h3-10H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: France Diclofop-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diclofop (considered variant diclofop-methyl) 07Oct2010 2010 doi:10.2903/j.efsa.2010.1718
+Diclofop-methyl 257-141-8 51338-27-3 single chemical entity Component is identical to the substance Diclofop-methyl 257-141-8 51338-27-3 Methyl 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoate Diclofop-Methyl C16H14Cl2O4 CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)Cl)Cl InChI=1S/C16H14Cl2O4/c1-10(16(19)20-2)21-12-4-6-13(7-5-12)22-15-8-3-11(17)9-14(15)18/h3-10H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: France Diclofop-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diclofop (considered variant diclofop-methyl) 07Oct2010 2010 doi:10.2903/j.efsa.2010.1718
+Diclofop-methyl 257-141-8 51338-27-3 single chemical entity Component is identical to the substance Diclofop-methyl 257-141-8 51338-27-3 Methyl 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoate Diclofop-Methyl C16H14Cl2O4 CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)Cl)Cl InChI=1S/C16H14Cl2O4/c1-10(16(19)20-2)21-12-4-6-13(7-5-12)22-15-8-3-11(17)9-14(15)18/h3-10H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: France Diclofop-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diclofop (considered variant diclofop-methyl) 07Oct2010 2010 doi:10.2903/j.efsa.2010.1718
+Diclofop-methyl 257-141-8 51338-27-3 single chemical entity Component is identical to the substance Diclofop-methyl 257-141-8 51338-27-3 Methyl 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoate Diclofop-Methyl C16H14Cl2O4 CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)Cl)Cl InChI=1S/C16H14Cl2O4/c1-10(16(19)20-2)21-12-4-6-13(7-5-12)22-15-8-3-11(17)9-14(15)18/h3-10H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: France Diclofop-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diclofop (considered variant diclofop-methyl) 07Oct2010 2010 doi:10.2903/j.efsa.2010.1718
+Diclofop-methyl 257-141-8 51338-27-3 single chemical entity Component is identical to the substance Diclofop-methyl 257-141-8 51338-27-3 Methyl 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoate Diclofop-Methyl C16H14Cl2O4 CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)Cl)Cl InChI=1S/C16H14Cl2O4/c1-10(16(19)20-2)21-12-4-6-13(7-5-12)22-15-8-3-11(17)9-14(15)18/h3-10H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: France Diclofop-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diclofop (considered variant diclofop-methyl) 07Oct2010 2010 doi:10.2903/j.efsa.2010.1718
+Diclofop-methyl 257-141-8 51338-27-3 single chemical entity Component is identical to the substance Diclofop-methyl 257-141-8 51338-27-3 Methyl 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoate Diclofop-Methyl C16H14Cl2O4 CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)Cl)Cl InChI=1S/C16H14Cl2O4/c1-10(16(19)20-2)21-12-4-6-13(7-5-12)22-15-8-3-11(17)9-14(15)18/h3-10H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: France Diclofop-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diclofop (considered variant diclofop-methyl) 07Oct2010 2010 doi:10.2903/j.efsa.2010.1718
+Diclofop-methyl 257-141-8 51338-27-3 single chemical entity Component is identical to the substance Diclofop-methyl 257-141-8 51338-27-3 Methyl 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoate Diclofop-Methyl C16H14Cl2O4 CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)Cl)Cl InChI=1S/C16H14Cl2O4/c1-10(16(19)20-2)21-12-4-6-13(7-5-12)22-15-8-3-11(17)9-14(15)18/h3-10H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: France Diclofop-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diclofop (considered variant diclofop-methyl) 07Oct2010 2010 doi:10.2903/j.efsa.2010.1718
+Diclofop-methyl 257-141-8 51338-27-3 single chemical entity Component is identical to the substance Diclofop-methyl 257-141-8 51338-27-3 Methyl 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoate Diclofop-Methyl C16H14Cl2O4 CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)Cl)Cl InChI=1S/C16H14Cl2O4/c1-10(16(19)20-2)21-12-4-6-13(7-5-12)22-15-8-3-11(17)9-14(15)18/h3-10H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: France Diclofop-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diclofop (considered variant diclofop-methyl) 07Oct2010 2010 doi:10.2903/j.efsa.2010.1718
+Diclofop-methyl 257-141-8 51338-27-3 single chemical entity Component is identical to the substance Diclofop-methyl 257-141-8 51338-27-3 Methyl 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoate Diclofop-Methyl C16H14Cl2O4 CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)Cl)Cl InChI=1S/C16H14Cl2O4/c1-10(16(19)20-2)21-12-4-6-13(7-5-12)22-15-8-3-11(17)9-14(15)18/h3-10H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: France Diclofop-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diclofop (considered variant diclofop-methyl) 07Oct2010 2010 doi:10.2903/j.efsa.2010.1718
+Diclofop-methyl 257-141-8 51338-27-3 single chemical entity Component is identical to the substance Diclofop-methyl 257-141-8 51338-27-3 Methyl 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoate Diclofop-Methyl C16H14Cl2O4 CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)Cl)Cl InChI=1S/C16H14Cl2O4/c1-10(16(19)20-2)21-12-4-6-13(7-5-12)22-15-8-3-11(17)9-14(15)18/h3-10H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: France Diclofop-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diclofop (considered variant diclofop-methyl) 07Oct2010 2010 doi:10.2903/j.efsa.2010.1718
+Diclofop-methyl 257-141-8 51338-27-3 single chemical entity Component is identical to the substance Diclofop-methyl 257-141-8 51338-27-3 Methyl 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoate Diclofop-Methyl C16H14Cl2O4 CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)Cl)Cl InChI=1S/C16H14Cl2O4/c1-10(16(19)20-2)21-12-4-6-13(7-5-12)22-15-8-3-11(17)9-14(15)18/h3-10H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: France Diclofop-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diclofop (considered variant diclofop-methyl) 07Oct2010 2010 doi:10.2903/j.efsa.2010.1718
+Diclofop-methyl 257-141-8 51338-27-3 single chemical entity Component is identical to the substance Diclofop-methyl 257-141-8 51338-27-3 Methyl 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoate Diclofop-Methyl C16H14Cl2O4 CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)Cl)Cl InChI=1S/C16H14Cl2O4/c1-10(16(19)20-2)21-12-4-6-13(7-5-12)22-15-8-3-11(17)9-14(15)18/h3-10H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data without Negative RMS: France Diclofop-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diclofop (considered variant diclofop-methyl) 07Oct2010 2010 doi:10.2903/j.efsa.2010.1718
+Diclofop-methyl 257-141-8 51338-27-3 single chemical entity Component is identical to the substance Diclofop-methyl 257-141-8 51338-27-3 Methyl 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoate Diclofop-Methyl C16H14Cl2O4 CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)Cl)Cl InChI=1S/C16H14Cl2O4/c1-10(16(19)20-2)21-12-4-6-13(7-5-12)22-15-8-3-11(17)9-14(15)18/h3-10H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data with Negative RMS: France Diclofop-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diclofop (considered variant diclofop-methyl) 07Oct2010 2010 doi:10.2903/j.efsa.2010.1718
+Diclofop-methyl 257-141-8 51338-27-3 single chemical entity Component is identical to the substance Diclofop-methyl 257-141-8 51338-27-3 Methyl 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoate Diclofop-Methyl C16H14Cl2O4 CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)Cl)Cl InChI=1S/C16H14Cl2O4/c1-10(16(19)20-2)21-12-4-6-13(7-5-12)22-15-8-3-11(17)9-14(15)18/h3-10H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported no data with Negative RMS: France Diclofop-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diclofop (considered variant diclofop-methyl) 07Oct2010 2010 doi:10.2903/j.efsa.2010.1718
+Diclofop-methyl 257-141-8 51338-27-3 single chemical entity Component is identical to the substance Diclofop-methyl 257-141-8 51338-27-3 Methyl 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoate Diclofop-Methyl C16H14Cl2O4 CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)Cl)Cl InChI=1S/C16H14Cl2O4/c1-10(16(19)20-2)21-12-4-6-13(7-5-12)22-15-8-3-11(17)9-14(15)18/h3-10H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported no data without Negative RMS: France Diclofop-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diclofop (considered variant diclofop-methyl) 07Oct2010 2010 doi:10.2903/j.efsa.2010.1718
+Diclofop-methyl 257-141-8 51338-27-3 single chemical entity Component is identical to the substance Diclofop-methyl 257-141-8 51338-27-3 Methyl 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoate Diclofop-Methyl C16H14Cl2O4 CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)Cl)Cl InChI=1S/C16H14Cl2O4/c1-10(16(19)20-2)21-12-4-6-13(7-5-12)22-15-8-3-11(17)9-14(15)18/h3-10H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported no data without Negative RMS: France Diclofop-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diclofop (considered variant diclofop-methyl) 07Oct2010 2010 doi:10.2903/j.efsa.2010.1718
+Diclofop-methyl 257-141-8 51338-27-3 single chemical entity Component is identical to the substance Diclofop-methyl 257-141-8 51338-27-3 Methyl 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoate Diclofop-Methyl C16H14Cl2O4 CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)Cl)Cl InChI=1S/C16H14Cl2O4/c1-10(16(19)20-2)21-12-4-6-13(7-5-12)22-15-8-3-11(17)9-14(15)18/h3-10H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported no data with Negative RMS: France Diclofop-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diclofop (considered variant diclofop-methyl) 07Oct2010 2010 doi:10.2903/j.efsa.2010.1718
+Diclofop-methyl 257-141-8 51338-27-3 single chemical entity Component is identical to the substance Diclofop-methyl 257-141-8 51338-27-3 Methyl 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoate Diclofop-Methyl C16H14Cl2O4 CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)Cl)Cl InChI=1S/C16H14Cl2O4/c1-10(16(19)20-2)21-12-4-6-13(7-5-12)22-15-8-3-11(17)9-14(15)18/h3-10H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Human (as organism) alveolar basal epithelial cells (A549) Not reported no data without Negative RMS: France Diclofop-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diclofop (considered variant diclofop-methyl) 07Oct2010 2010 doi:10.2903/j.efsa.2010.1718
+Diclofop-methyl 257-141-8 51338-27-3 single chemical entity Component is identical to the substance Diclofop-methyl 257-141-8 51338-27-3 Methyl 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoate Diclofop-Methyl C16H14Cl2O4 CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)Cl)Cl InChI=1S/C16H14Cl2O4/c1-10(16(19)20-2)21-12-4-6-13(7-5-12)22-15-8-3-11(17)9-14(15)18/h3-10H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Human (as organism) alveolar basal epithelial cells (A549) Not reported no data with Negative RMS: France Diclofop-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diclofop (considered variant diclofop-methyl) 07Oct2010 2010 doi:10.2903/j.efsa.2010.1718
+Diclofop-methyl 257-141-8 51338-27-3 single chemical entity Component is identical to the substance Diclofop-methyl 257-141-8 51338-27-3 Methyl 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoate Diclofop-Methyl C16H14Cl2O4 CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)Cl)Cl InChI=1S/C16H14Cl2O4/c1-10(16(19)20-2)21-12-4-6-13(7-5-12)22-15-8-3-11(17)9-14(15)18/h3-10H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI Male/Female oral: gavage 72.0000000000 h yes not applicable Negative no evidence RMS: France Diclofop-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diclofop (considered variant diclofop-methyl) 07Oct2010 2010 doi:10.2903/j.efsa.2010.1718
+Diclofop-methyl 257-141-8 51338-27-3 single chemical entity Component is identical to the substance Diclofop-methyl 257-141-8 51338-27-3 Methyl 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoate Diclofop-Methyl C16H14Cl2O4 CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)Cl)Cl InChI=1S/C16H14Cl2O4/c1-10(16(19)20-2)21-12-4-6-13(7-5-12)22-15-8-3-11(17)9-14(15)18/h3-10H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable Hamster (as animal) Not reported 10 Male/Female oral: gavage 24.0000000000 h yes not applicable Negative no evidence RMS: France Diclofop-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diclofop (considered variant diclofop-methyl) 07Oct2010 2010 doi:10.2903/j.efsa.2010.1718
+Diclofop-methyl 257-141-8 51338-27-3 single chemical entity Component is identical to the substance Diclofop-methyl 257-141-8 51338-27-3 Methyl 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoate Diclofop-Methyl C16H14Cl2O4 CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)Cl)Cl InChI=1S/C16H14Cl2O4/c1-10(16(19)20-2)21-12-4-6-13(7-5-12)22-15-8-3-11(17)9-14(15)18/h3-10H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable Hamster (as animal) Not reported 10 Male/Female oral: gavage 12.0000000000 h yes not applicable Negative no evidence RMS: France Diclofop-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diclofop (considered variant diclofop-methyl) 07Oct2010 2010 doi:10.2903/j.efsa.2010.1718
+Diclofop-methyl 257-141-8 51338-27-3 single chemical entity Component is identical to the substance Diclofop-methyl 257-141-8 51338-27-3 Methyl 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoate Diclofop-Methyl C16H14Cl2O4 CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)Cl)Cl InChI=1S/C16H14Cl2O4/c1-10(16(19)20-2)21-12-4-6-13(7-5-12)22-15-8-3-11(17)9-14(15)18/h3-10H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable Hamster (as animal) Not reported 10 Male/Female oral: gavage 48.0000000000 h yes not applicable Negative no evidence RMS: France Diclofop-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diclofop (considered variant diclofop-methyl) 07Oct2010 2010 doi:10.2903/j.efsa.2010.1718
+Chlorsulfuron 265-268-5 64902-72-3 single chemical entity Component is identical to the substance Chlorsulfuron 265-268-5 64902-72-3 2-chloro-N-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)amino]carbonyl}benzenesulfonamide Chlorsulfuron C12H12ClN5O4S Cc2nc(NC(=O)NS(=O)(=O)c1ccccc1Cl)nc(OC)n2 InChI=1S/C12H12ClN5O4S/c1-7-14-10(17-12(15-7)22-2)16-11(19)18-23(20,21)9-6-4-3-5-8(9)13/h3-6H,1-2H3,(H2,14,15,16,17,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Greece Chlorsulfuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron 06Mar2009 2009 doi:10.2903/j.efsa.2009.201r
+Chlorsulfuron 265-268-5 64902-72-3 single chemical entity Component is identical to the substance Chlorsulfuron 265-268-5 64902-72-3 2-chloro-N-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)amino]carbonyl}benzenesulfonamide Chlorsulfuron C12H12ClN5O4S Cc2nc(NC(=O)NS(=O)(=O)c1ccccc1Cl)nc(OC)n2 InChI=1S/C12H12ClN5O4S/c1-7-14-10(17-12(15-7)22-2)16-11(19)18-23(20,21)9-6-4-3-5-8(9)13/h3-6H,1-2H3,(H2,14,15,16,17,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes with Negative RMS: Greece Chlorsulfuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron 06Mar2009 2009 doi:10.2903/j.efsa.2009.201r
+Chlorsulfuron 265-268-5 64902-72-3 single chemical entity Component is identical to the substance Chlorsulfuron 265-268-5 64902-72-3 2-chloro-N-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)amino]carbonyl}benzenesulfonamide Chlorsulfuron C12H12ClN5O4S Cc2nc(NC(=O)NS(=O)(=O)c1ccccc1Cl)nc(OC)n2 InChI=1S/C12H12ClN5O4S/c1-7-14-10(17-12(15-7)22-2)16-11(19)18-23(20,21)9-6-4-3-5-8(9)13/h3-6H,1-2H3,(H2,14,15,16,17,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Greece Chlorsulfuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron 06Mar2009 2009 doi:10.2903/j.efsa.2009.201r
+Chlorsulfuron 265-268-5 64902-72-3 single chemical entity Component is identical to the substance Chlorsulfuron 265-268-5 64902-72-3 2-chloro-N-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)amino]carbonyl}benzenesulfonamide Chlorsulfuron C12H12ClN5O4S Cc2nc(NC(=O)NS(=O)(=O)c1ccccc1Cl)nc(OC)n2 InChI=1S/C12H12ClN5O4S/c1-7-14-10(17-12(15-7)22-2)16-11(19)18-23(20,21)9-6-4-3-5-8(9)13/h3-6H,1-2H3,(H2,14,15,16,17,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Greece Chlorsulfuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron 06Mar2009 2009 doi:10.2903/j.efsa.2009.201r
+Chlorsulfuron 265-268-5 64902-72-3 single chemical entity Component is identical to the substance Chlorsulfuron 265-268-5 64902-72-3 2-chloro-N-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)amino]carbonyl}benzenesulfonamide Chlorsulfuron C12H12ClN5O4S Cc2nc(NC(=O)NS(=O)(=O)c1ccccc1Cl)nc(OC)n2 InChI=1S/C12H12ClN5O4S/c1-7-14-10(17-12(15-7)22-2)16-11(19)18-23(20,21)9-6-4-3-5-8(9)13/h3-6H,1-2H3,(H2,14,15,16,17,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Greece Chlorsulfuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron 06Mar2009 2009 doi:10.2903/j.efsa.2009.201r
+Chlorsulfuron 265-268-5 64902-72-3 single chemical entity Component is identical to the substance Chlorsulfuron 265-268-5 64902-72-3 2-chloro-N-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)amino]carbonyl}benzenesulfonamide Chlorsulfuron C12H12ClN5O4S Cc2nc(NC(=O)NS(=O)(=O)c1ccccc1Cl)nc(OC)n2 InChI=1S/C12H12ClN5O4S/c1-7-14-10(17-12(15-7)22-2)16-11(19)18-23(20,21)9-6-4-3-5-8(9)13/h3-6H,1-2H3,(H2,14,15,16,17,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Greece Chlorsulfuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron 06Mar2009 2009 doi:10.2903/j.efsa.2009.201r
+Chlorsulfuron 265-268-5 64902-72-3 single chemical entity Component is identical to the substance Chlorsulfuron 265-268-5 64902-72-3 2-chloro-N-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)amino]carbonyl}benzenesulfonamide Chlorsulfuron C12H12ClN5O4S Cc2nc(NC(=O)NS(=O)(=O)c1ccccc1Cl)nc(OC)n2 InChI=1S/C12H12ClN5O4S/c1-7-14-10(17-12(15-7)22-2)16-11(19)18-23(20,21)9-6-4-3-5-8(9)13/h3-6H,1-2H3,(H2,14,15,16,17,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Greece Chlorsulfuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron 06Mar2009 2009 doi:10.2903/j.efsa.2009.201r
+Chlorsulfuron 265-268-5 64902-72-3 single chemical entity Component is identical to the substance Chlorsulfuron 265-268-5 64902-72-3 2-chloro-N-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)amino]carbonyl}benzenesulfonamide Chlorsulfuron C12H12ClN5O4S Cc2nc(NC(=O)NS(=O)(=O)c1ccccc1Cl)nc(OC)n2 InChI=1S/C12H12ClN5O4S/c1-7-14-10(17-12(15-7)22-2)16-11(19)18-23(20,21)9-6-4-3-5-8(9)13/h3-6H,1-2H3,(H2,14,15,16,17,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes without Negative RMS: Greece Chlorsulfuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron 06Mar2009 2009 doi:10.2903/j.efsa.2009.201r
+Chlorsulfuron 265-268-5 64902-72-3 single chemical entity Component is identical to the substance Chlorsulfuron 265-268-5 64902-72-3 2-chloro-N-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)amino]carbonyl}benzenesulfonamide Chlorsulfuron C12H12ClN5O4S Cc2nc(NC(=O)NS(=O)(=O)c1ccccc1Cl)nc(OC)n2 InChI=1S/C12H12ClN5O4S/c1-7-14-10(17-12(15-7)22-2)16-11(19)18-23(20,21)9-6-4-3-5-8(9)13/h3-6H,1-2H3,(H2,14,15,16,17,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes without Negative RMS: Greece Chlorsulfuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron 06Mar2009 2009 doi:10.2903/j.efsa.2009.201r
+Chlorsulfuron 265-268-5 64902-72-3 single chemical entity Component is identical to the substance Chlorsulfuron 265-268-5 64902-72-3 2-chloro-N-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)amino]carbonyl}benzenesulfonamide Chlorsulfuron C12H12ClN5O4S Cc2nc(NC(=O)NS(=O)(=O)c1ccccc1Cl)nc(OC)n2 InChI=1S/C12H12ClN5O4S/c1-7-14-10(17-12(15-7)22-2)16-11(19)18-23(20,21)9-6-4-3-5-8(9)13/h3-6H,1-2H3,(H2,14,15,16,17,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes with Negative RMS: Greece Chlorsulfuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron 06Mar2009 2009 doi:10.2903/j.efsa.2009.201r
+Chlorsulfuron 265-268-5 64902-72-3 single chemical entity Component is identical to the substance Chlorsulfuron 265-268-5 64902-72-3 2-chloro-N-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)amino]carbonyl}benzenesulfonamide Chlorsulfuron C12H12ClN5O4S Cc2nc(NC(=O)NS(=O)(=O)c1ccccc1Cl)nc(OC)n2 InChI=1S/C12H12ClN5O4S/c1-7-14-10(17-12(15-7)22-2)16-11(19)18-23(20,21)9-6-4-3-5-8(9)13/h3-6H,1-2H3,(H2,14,15,16,17,18,19) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: Greece Chlorsulfuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron 06Mar2009 2009 doi:10.2903/j.efsa.2009.201r
+Chlorsulfuron 265-268-5 64902-72-3 single chemical entity Component is identical to the substance Chlorsulfuron 265-268-5 64902-72-3 2-chloro-N-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)amino]carbonyl}benzenesulfonamide Chlorsulfuron C12H12ClN5O4S Cc2nc(NC(=O)NS(=O)(=O)c1ccccc1Cl)nc(OC)n2 InChI=1S/C12H12ClN5O4S/c1-7-14-10(17-12(15-7)22-2)16-11(19)18-23(20,21)9-6-4-3-5-8(9)13/h3-6H,1-2H3,(H2,14,15,16,17,18,19) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: Greece Chlorsulfuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron 06Mar2009 2009 doi:10.2903/j.efsa.2009.201r
+Chlorsulfuron 265-268-5 64902-72-3 single chemical entity Component is identical to the substance Chlorsulfuron 265-268-5 64902-72-3 2-chloro-N-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)amino]carbonyl}benzenesulfonamide Chlorsulfuron C12H12ClN5O4S Cc2nc(NC(=O)NS(=O)(=O)c1ccccc1Cl)nc(OC)n2 InChI=1S/C12H12ClN5O4S/c1-7-14-10(17-12(15-7)22-2)16-11(19)18-23(20,21)9-6-4-3-5-8(9)13/h3-6H,1-2H3,(H2,14,15,16,17,18,19) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Greece Chlorsulfuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron 06Mar2009 2009 doi:10.2903/j.efsa.2009.201r
+Chlorsulfuron 265-268-5 64902-72-3 single chemical entity Component is identical to the substance Chlorsulfuron 265-268-5 64902-72-3 2-chloro-N-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)amino]carbonyl}benzenesulfonamide Chlorsulfuron C12H12ClN5O4S Cc2nc(NC(=O)NS(=O)(=O)c1ccccc1Cl)nc(OC)n2 InChI=1S/C12H12ClN5O4S/c1-7-14-10(17-12(15-7)22-2)16-11(19)18-23(20,21)9-6-4-3-5-8(9)13/h3-6H,1-2H3,(H2,14,15,16,17,18,19) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Greece Chlorsulfuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron 06Mar2009 2009 doi:10.2903/j.efsa.2009.201r
+Chlorsulfuron 265-268-5 64902-72-3 single chemical entity Component is identical to the substance Chlorsulfuron 265-268-5 64902-72-3 2-chloro-N-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)amino]carbonyl}benzenesulfonamide Chlorsulfuron C12H12ClN5O4S Cc2nc(NC(=O)NS(=O)(=O)c1ccccc1Cl)nc(OC)n2 InChI=1S/C12H12ClN5O4S/c1-7-14-10(17-12(15-7)22-2)16-11(19)18-23(20,21)9-6-4-3-5-8(9)13/h3-6H,1-2H3,(H2,14,15,16,17,18,19) organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Greece Chlorsulfuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron 06Mar2009 2009 doi:10.2903/j.efsa.2009.201r
+Chlorsulfuron 265-268-5 64902-72-3 single chemical entity Component is identical to the substance Chlorsulfuron 265-268-5 64902-72-3 2-chloro-N-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)amino]carbonyl}benzenesulfonamide Chlorsulfuron C12H12ClN5O4S Cc2nc(NC(=O)NS(=O)(=O)c1ccccc1Cl)nc(OC)n2 InChI=1S/C12H12ClN5O4S/c1-7-14-10(17-12(15-7)22-2)16-11(19)18-23(20,21)9-6-4-3-5-8(9)13/h3-6H,1-2H3,(H2,14,15,16,17,18,19) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Greece Chlorsulfuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron 06Mar2009 2009 doi:10.2903/j.efsa.2009.201r
+Chlorsulfuron 265-268-5 64902-72-3 single chemical entity Component is identical to the substance Chlorsulfuron 265-268-5 64902-72-3 2-chloro-N-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)amino]carbonyl}benzenesulfonamide Chlorsulfuron C12H12ClN5O4S Cc2nc(NC(=O)NS(=O)(=O)c1ccccc1Cl)nc(OC)n2 InChI=1S/C12H12ClN5O4S/c1-7-14-10(17-12(15-7)22-2)16-11(19)18-23(20,21)9-6-4-3-5-8(9)13/h3-6H,1-2H3,(H2,14,15,16,17,18,19) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Greece Chlorsulfuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron 06Mar2009 2009 doi:10.2903/j.efsa.2009.201r
+Chlorsulfuron 265-268-5 64902-72-3 single chemical entity Component is identical to the substance Chlorsulfuron 265-268-5 64902-72-3 2-chloro-N-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)amino]carbonyl}benzenesulfonamide Chlorsulfuron C12H12ClN5O4S Cc2nc(NC(=O)NS(=O)(=O)c1ccccc1Cl)nc(OC)n2 InChI=1S/C12H12ClN5O4S/c1-7-14-10(17-12(15-7)22-2)16-11(19)18-23(20,21)9-6-4-3-5-8(9)13/h3-6H,1-2H3,(H2,14,15,16,17,18,19) organic compound Other Other chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) Yes Acceptable Rat (as animal) Sprague-Dawley 10 Male oral: feed 10.0000000000 week yes, concurrent vehicle not applicable Negative RMS: Greece Chlorsulfuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron 06Mar2009 2009 doi:10.2903/j.efsa.2009.201r
+Chlorsulfuron 265-268-5 64902-72-3 single chemical entity Component is a metabolite of the substance 2-chlorobenzenesulfonamide 230-156-7 6961-82-6 2-chlorobenzenesulfonamide Not in list C6H6ClNO2S C1=CC=C(C(=C1)S(=O)(=O)N)Cl InChI=1S/C6H6ClNO2S/c7-5-3-1-2-4-6(5)11(8,9)10/h1-4H,(H2,8,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Greece Chlorsulfuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron 06Mar2009 2009 doi:10.2903/j.efsa.2009.201r
+Chlorsulfuron 265-268-5 64902-72-3 single chemical entity Component is a metabolite of the substance 2-chlorobenzenesulfonamide 230-156-7 6961-82-6 2-chlorobenzenesulfonamide Not in list C6H6ClNO2S C1=CC=C(C(=C1)S(=O)(=O)N)Cl InChI=1S/C6H6ClNO2S/c7-5-3-1-2-4-6(5)11(8,9)10/h1-4H,(H2,8,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Greece Chlorsulfuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron 06Mar2009 2009 doi:10.2903/j.efsa.2009.201r
+Chlorsulfuron 265-268-5 64902-72-3 single chemical entity Component is a metabolite of the substance 2-chlorobenzenesulfonamide 230-156-7 6961-82-6 2-chlorobenzenesulfonamide Not in list C6H6ClNO2S C1=CC=C(C(=C1)S(=O)(=O)N)Cl InChI=1S/C6H6ClNO2S/c7-5-3-1-2-4-6(5)11(8,9)10/h1-4H,(H2,8,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Greece Chlorsulfuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron 06Mar2009 2009 doi:10.2903/j.efsa.2009.201r
+Chlorsulfuron 265-268-5 64902-72-3 single chemical entity Component is a metabolite of the substance 2-chlorobenzenesulfonamide 230-156-7 6961-82-6 2-chlorobenzenesulfonamide Not in list C6H6ClNO2S C1=CC=C(C(=C1)S(=O)(=O)N)Cl InChI=1S/C6H6ClNO2S/c7-5-3-1-2-4-6(5)11(8,9)10/h1-4H,(H2,8,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Greece Chlorsulfuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron 06Mar2009 2009 doi:10.2903/j.efsa.2009.201r
+Chlorsulfuron 265-268-5 64902-72-3 single chemical entity Component is a metabolite of the substance 2-chlorobenzenesulfonamide 230-156-7 6961-82-6 2-chlorobenzenesulfonamide Not in list C6H6ClNO2S C1=CC=C(C(=C1)S(=O)(=O)N)Cl InChI=1S/C6H6ClNO2S/c7-5-3-1-2-4-6(5)11(8,9)10/h1-4H,(H2,8,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Greece Chlorsulfuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron 06Mar2009 2009 doi:10.2903/j.efsa.2009.201r
+Chlorsulfuron 265-268-5 64902-72-3 single chemical entity Component is a metabolite of the substance 2-chlorobenzenesulfonamide 230-156-7 6961-82-6 2-chlorobenzenesulfonamide Not in list C6H6ClNO2S C1=CC=C(C(=C1)S(=O)(=O)N)Cl InChI=1S/C6H6ClNO2S/c7-5-3-1-2-4-6(5)11(8,9)10/h1-4H,(H2,8,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Greece Chlorsulfuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron 06Mar2009 2009 doi:10.2903/j.efsa.2009.201r
+Chlorsulfuron 265-268-5 64902-72-3 single chemical entity Component is a metabolite of the substance 2-chlorobenzenesulfonamide 230-156-7 6961-82-6 2-chlorobenzenesulfonamide Not in list C6H6ClNO2S C1=CC=C(C(=C1)S(=O)(=O)N)Cl InChI=1S/C6H6ClNO2S/c7-5-3-1-2-4-6(5)11(8,9)10/h1-4H,(H2,8,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Greece Chlorsulfuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron 06Mar2009 2009 doi:10.2903/j.efsa.2009.201r
+Chlorsulfuron 265-268-5 64902-72-3 single chemical entity Component is a metabolite of the substance 2-chlorobenzenesulfonamide 230-156-7 6961-82-6 2-chlorobenzenesulfonamide Not in list C6H6ClNO2S C1=CC=C(C(=C1)S(=O)(=O)N)Cl InChI=1S/C6H6ClNO2S/c7-5-3-1-2-4-6(5)11(8,9)10/h1-4H,(H2,8,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Greece Chlorsulfuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron 06Mar2009 2009 doi:10.2903/j.efsa.2009.201r
+Chlorsulfuron 265-268-5 64902-72-3 single chemical entity Component is a metabolite of the substance 2-chlorobenzenesulfonamide 230-156-7 6961-82-6 2-chlorobenzenesulfonamide Not in list C6H6ClNO2S C1=CC=C(C(=C1)S(=O)(=O)N)Cl InChI=1S/C6H6ClNO2S/c7-5-3-1-2-4-6(5)11(8,9)10/h1-4H,(H2,8,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Greece Chlorsulfuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron 06Mar2009 2009 doi:10.2903/j.efsa.2009.201r
+Chlorsulfuron 265-268-5 64902-72-3 single chemical entity Component is a metabolite of the substance 2-chlorobenzenesulfonamide 230-156-7 6961-82-6 2-chlorobenzenesulfonamide Not in list C6H6ClNO2S C1=CC=C(C(=C1)S(=O)(=O)N)Cl InChI=1S/C6H6ClNO2S/c7-5-3-1-2-4-6(5)11(8,9)10/h1-4H,(H2,8,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Greece Chlorsulfuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron 06Mar2009 2009 doi:10.2903/j.efsa.2009.201r
+Chlorsulfuron 265-268-5 64902-72-3 single chemical entity Component is a metabolite of the substance 2-chlorobenzenesulfonamide 230-156-7 6961-82-6 2-chlorobenzenesulfonamide Not in list C6H6ClNO2S C1=CC=C(C(=C1)S(=O)(=O)N)Cl InChI=1S/C6H6ClNO2S/c7-5-3-1-2-4-6(5)11(8,9)10/h1-4H,(H2,8,9,10) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Greece Chlorsulfuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron 06Mar2009 2009 doi:10.2903/j.efsa.2009.201r
+Chlorsulfuron 265-268-5 64902-72-3 single chemical entity Component is a metabolite of the substance 2-chlorobenzenesulfonamide 230-156-7 6961-82-6 2-chlorobenzenesulfonamide Not in list C6H6ClNO2S C1=CC=C(C(=C1)S(=O)(=O)N)Cl InChI=1S/C6H6ClNO2S/c7-5-3-1-2-4-6(5)11(8,9)10/h1-4H,(H2,8,9,10) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Greece Chlorsulfuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron 06Mar2009 2009 doi:10.2903/j.efsa.2009.201r
+Chlorsulfuron 265-268-5 64902-72-3 single chemical entity Component is a metabolite of the substance N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide N'-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid Not in list C9H10ClN5O4S O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Greece Chlorsulfuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron 06Mar2009 2009 doi:10.2903/j.efsa.2009.201r
+Chlorsulfuron 265-268-5 64902-72-3 single chemical entity Component is a metabolite of the substance N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide N'-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid Not in list C9H10ClN5O4S O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Greece Chlorsulfuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron 06Mar2009 2009 doi:10.2903/j.efsa.2009.201r
+Chlorsulfuron 265-268-5 64902-72-3 single chemical entity Component is a metabolite of the substance N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide N'-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid Not in list C9H10ClN5O4S O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Greece Chlorsulfuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron 06Mar2009 2009 doi:10.2903/j.efsa.2009.201r
+Chlorsulfuron 265-268-5 64902-72-3 single chemical entity Component is a metabolite of the substance N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide N'-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid Not in list C9H10ClN5O4S O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Greece Chlorsulfuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron 06Mar2009 2009 doi:10.2903/j.efsa.2009.201r
+Chlorsulfuron 265-268-5 64902-72-3 single chemical entity Component is a metabolite of the substance N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide N'-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid Not in list C9H10ClN5O4S O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Greece Chlorsulfuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron 06Mar2009 2009 doi:10.2903/j.efsa.2009.201r
+Chlorsulfuron 265-268-5 64902-72-3 single chemical entity Component is a metabolite of the substance N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide N'-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid Not in list C9H10ClN5O4S O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Greece Chlorsulfuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron 06Mar2009 2009 doi:10.2903/j.efsa.2009.201r
+Chlorsulfuron 265-268-5 64902-72-3 single chemical entity Component is a metabolite of the substance N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide N'-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid Not in list C9H10ClN5O4S O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Greece Chlorsulfuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron 06Mar2009 2009 doi:10.2903/j.efsa.2009.201r
+Chlorsulfuron 265-268-5 64902-72-3 single chemical entity Component is a metabolite of the substance N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide N'-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid Not in list C9H10ClN5O4S O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Greece Chlorsulfuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron 06Mar2009 2009 doi:10.2903/j.efsa.2009.201r
+Chlorsulfuron 265-268-5 64902-72-3 single chemical entity Component is a metabolite of the substance N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide N'-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid Not in list C9H10ClN5O4S O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Greece Chlorsulfuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron 06Mar2009 2009 doi:10.2903/j.efsa.2009.201r
+Chlorsulfuron 265-268-5 64902-72-3 single chemical entity Component is a metabolite of the substance N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide N'-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid Not in list C9H10ClN5O4S O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Greece Chlorsulfuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron 06Mar2009 2009 doi:10.2903/j.efsa.2009.201r
+Chlorsulfuron 265-268-5 64902-72-3 single chemical entity Component is a metabolite of the substance N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide N'-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid Not in list C9H10ClN5O4S O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Greece Chlorsulfuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron 06Mar2009 2009 doi:10.2903/j.efsa.2009.201r
+Chlorsulfuron 265-268-5 64902-72-3 single chemical entity Component is a metabolite of the substance N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide N'-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid Not in list C9H10ClN5O4S O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Greece Chlorsulfuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron 06Mar2009 2009 doi:10.2903/j.efsa.2009.201r
+Chlorsulfuron 265-268-5 64902-72-3 single chemical entity Component is a metabolite of the substance N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide N'-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid Not in list C9H10ClN5O4S O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Greece Chlorsulfuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron 06Mar2009 2009 doi:10.2903/j.efsa.2009.201r
+Chlorsulfuron 265-268-5 64902-72-3 single chemical entity Component is a metabolite of the substance N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide N'-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid Not in list C9H10ClN5O4S O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Greece Chlorsulfuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron 06Mar2009 2009 doi:10.2903/j.efsa.2009.201r
+Clopyralid 216-935-4 1702-17-6 single chemical entity Component is identical to the substance Clopyralid 216-935-4 1702-17-6 3,6-dichloropyridine-2-carboxylic acid Clopyralid C6H3Cl2NO2 C1=CC(=NC(=C1Cl)C(=O)O)Cl InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Finland Clopyralid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid 23Jan2006 2006 doi: 10.2903/j.efsa.2006.50r
+Clopyralid 216-935-4 1702-17-6 single chemical entity Component is identical to the substance Clopyralid 216-935-4 1702-17-6 3,6-dichloropyridine-2-carboxylic acid Clopyralid C6H3Cl2NO2 C1=CC(=NC(=C1Cl)C(=O)O)Cl InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Finland Clopyralid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid 23Jan2006 2006 doi: 10.2903/j.efsa.2006.50r
+Clopyralid 216-935-4 1702-17-6 single chemical entity Component is identical to the substance Clopyralid 216-935-4 1702-17-6 3,6-dichloropyridine-2-carboxylic acid Clopyralid C6H3Cl2NO2 C1=CC(=NC(=C1Cl)C(=O)O)Cl InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Finland Clopyralid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid 23Jan2006 2006 doi: 10.2903/j.efsa.2006.50r
+Clopyralid 216-935-4 1702-17-6 single chemical entity Component is identical to the substance Clopyralid 216-935-4 1702-17-6 3,6-dichloropyridine-2-carboxylic acid Clopyralid C6H3Cl2NO2 C1=CC(=NC(=C1Cl)C(=O)O)Cl InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Finland Clopyralid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid 23Jan2006 2006 doi: 10.2903/j.efsa.2006.50r
+Clopyralid 216-935-4 1702-17-6 single chemical entity Component is identical to the substance Clopyralid 216-935-4 1702-17-6 3,6-dichloropyridine-2-carboxylic acid Clopyralid C6H3Cl2NO2 C1=CC(=NC(=C1Cl)C(=O)O)Cl InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Finland Clopyralid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid 23Jan2006 2006 doi: 10.2903/j.efsa.2006.50r
+Clopyralid 216-935-4 1702-17-6 single chemical entity Component is identical to the substance Clopyralid 216-935-4 1702-17-6 3,6-dichloropyridine-2-carboxylic acid Clopyralid C6H3Cl2NO2 C1=CC(=NC(=C1Cl)C(=O)O)Cl InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Finland Clopyralid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid 23Jan2006 2006 doi: 10.2903/j.efsa.2006.50r
+Clopyralid 216-935-4 1702-17-6 single chemical entity Component is identical to the substance Clopyralid 216-935-4 1702-17-6 3,6-dichloropyridine-2-carboxylic acid Clopyralid C6H3Cl2NO2 C1=CC(=NC(=C1Cl)C(=O)O)Cl InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Finland Clopyralid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid 23Jan2006 2006 doi: 10.2903/j.efsa.2006.50r
+Clopyralid 216-935-4 1702-17-6 single chemical entity Component is identical to the substance Clopyralid 216-935-4 1702-17-6 3,6-dichloropyridine-2-carboxylic acid Clopyralid C6H3Cl2NO2 C1=CC(=NC(=C1Cl)C(=O)O)Cl InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Finland Clopyralid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid 23Jan2006 2006 doi: 10.2903/j.efsa.2006.50r
+Clopyralid 216-935-4 1702-17-6 single chemical entity Component is identical to the substance Clopyralid 216-935-4 1702-17-6 3,6-dichloropyridine-2-carboxylic acid Clopyralid C6H3Cl2NO2 C1=CC(=NC(=C1Cl)C(=O)O)Cl InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Finland Clopyralid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid 23Jan2006 2006 doi: 10.2903/j.efsa.2006.50r
+Clopyralid 216-935-4 1702-17-6 single chemical entity Component is identical to the substance Clopyralid 216-935-4 1702-17-6 3,6-dichloropyridine-2-carboxylic acid Clopyralid C6H3Cl2NO2 C1=CC(=NC(=C1Cl)C(=O)O)Cl InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Finland Clopyralid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid 23Jan2006 2006 doi: 10.2903/j.efsa.2006.50r
+Clopyralid 216-935-4 1702-17-6 single chemical entity Component is identical to the substance Clopyralid 216-935-4 1702-17-6 3,6-dichloropyridine-2-carboxylic acid Clopyralid C6H3Cl2NO2 C1=CC(=NC(=C1Cl)C(=O)O)Cl InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Finland Clopyralid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid 23Jan2006 2006 doi: 10.2903/j.efsa.2006.50r
+Clopyralid 216-935-4 1702-17-6 single chemical entity Component is identical to the substance Clopyralid 216-935-4 1702-17-6 3,6-dichloropyridine-2-carboxylic acid Clopyralid C6H3Cl2NO2 C1=CC(=NC(=C1Cl)C(=O)O)Cl InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Finland Clopyralid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid 23Jan2006 2006 doi: 10.2903/j.efsa.2006.50r
+Clopyralid 216-935-4 1702-17-6 single chemical entity Component is identical to the substance Clopyralid 216-935-4 1702-17-6 3,6-dichloropyridine-2-carboxylic acid Clopyralid C6H3Cl2NO2 C1=CC(=NC(=C1Cl)C(=O)O)Cl InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Finland Clopyralid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid 23Jan2006 2006 doi: 10.2903/j.efsa.2006.50r
+Clopyralid 216-935-4 1702-17-6 single chemical entity Component is identical to the substance Clopyralid 216-935-4 1702-17-6 3,6-dichloropyridine-2-carboxylic acid Clopyralid C6H3Cl2NO2 C1=CC(=NC(=C1Cl)C(=O)O)Cl InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Finland Clopyralid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid 23Jan2006 2006 doi: 10.2903/j.efsa.2006.50r
+Clopyralid 216-935-4 1702-17-6 single chemical entity Component is identical to the substance Clopyralid 216-935-4 1702-17-6 3,6-dichloropyridine-2-carboxylic acid Clopyralid C6H3Cl2NO2 C1=CC(=NC(=C1Cl)C(=O)O)Cl InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Finland Clopyralid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid 23Jan2006 2006 doi: 10.2903/j.efsa.2006.50r
+Clopyralid 216-935-4 1702-17-6 single chemical entity Component is identical to the substance Clopyralid 216-935-4 1702-17-6 3,6-dichloropyridine-2-carboxylic acid Clopyralid C6H3Cl2NO2 C1=CC(=NC(=C1Cl)C(=O)O)Cl InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Finland Clopyralid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid 23Jan2006 2006 doi: 10.2903/j.efsa.2006.50r
+Clopyralid 216-935-4 1702-17-6 single chemical entity Component is identical to the substance Clopyralid 216-935-4 1702-17-6 3,6-dichloropyridine-2-carboxylic acid Clopyralid C6H3Cl2NO2 C1=CC(=NC(=C1Cl)C(=O)O)Cl InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Finland Clopyralid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid 23Jan2006 2006 doi: 10.2903/j.efsa.2006.50r
+Clopyralid 216-935-4 1702-17-6 single chemical entity Component is identical to the substance Clopyralid 216-935-4 1702-17-6 3,6-dichloropyridine-2-carboxylic acid Clopyralid C6H3Cl2NO2 C1=CC(=NC(=C1Cl)C(=O)O)Cl InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Finland Clopyralid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid 23Jan2006 2006 doi: 10.2903/j.efsa.2006.50r
+Clopyralid 216-935-4 1702-17-6 single chemical entity Component is identical to the substance Clopyralid 216-935-4 1702-17-6 3,6-dichloropyridine-2-carboxylic acid Clopyralid C6H3Cl2NO2 C1=CC(=NC(=C1Cl)C(=O)O)Cl InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Finland Clopyralid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid 23Jan2006 2006 doi: 10.2903/j.efsa.2006.50r
+Clopyralid 216-935-4 1702-17-6 single chemical entity Component is identical to the substance Clopyralid 216-935-4 1702-17-6 3,6-dichloropyridine-2-carboxylic acid Clopyralid C6H3Cl2NO2 C1=CC(=NC(=C1Cl)C(=O)O)Cl InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Finland Clopyralid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid 23Jan2006 2006 doi: 10.2903/j.efsa.2006.50r
+Clopyralid 216-935-4 1702-17-6 single chemical entity Component is identical to the substance Clopyralid 216-935-4 1702-17-6 3,6-dichloropyridine-2-carboxylic acid Clopyralid C6H3Cl2NO2 C1=CC(=NC(=C1Cl)C(=O)O)Cl InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Rat (as animal) hepatocytes Not reported yes without Negative RMS: Finland Clopyralid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid 23Jan2006 2006 doi: 10.2903/j.efsa.2006.50r
+Clopyralid 216-935-4 1702-17-6 single chemical entity Component is identical to the substance Clopyralid 216-935-4 1702-17-6 3,6-dichloropyridine-2-carboxylic acid Clopyralid C6H3Cl2NO2 C1=CC(=NC(=C1Cl)C(=O)O)Cl InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Salmonella typhimurium (as organism) G46 Not reported yes, concurrent vehicle without Negative RMS: Finland Clopyralid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid 23Jan2006 2006 doi: 10.2903/j.efsa.2006.50r
+Clopyralid 216-935-4 1702-17-6 single chemical entity Component is identical to the substance Clopyralid 216-935-4 1702-17-6 3,6-dichloropyridine-2-carboxylic acid Clopyralid C6H3Cl2NO2 C1=CC(=NC(=C1Cl)C(=O)O)Cl InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Saccharomyces cerevisiae (as organism) D3 Not reported yes, concurrent vehicle without Negative RMS: Finland Clopyralid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid 23Jan2006 2006 doi: 10.2903/j.efsa.2006.50r
+Clopyralid 216-935-4 1702-17-6 single chemical entity Component is identical to the substance Clopyralid 216-935-4 1702-17-6 3,6-dichloropyridine-2-carboxylic acid Clopyralid C6H3Cl2NO2 C1=CC(=NC(=C1Cl)C(=O)O)Cl InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation other in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) ICR 10 Male oral: gavage 4.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Finland Clopyralid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid 23Jan2006 2006 doi: 10.2903/j.efsa.2006.50r
+Clopyralid 216-935-4 1702-17-6 single chemical entity Component is identical to the substance Clopyralid 216-935-4 1702-17-6 3,6-dichloropyridine-2-carboxylic acid Clopyralid C6H3Cl2NO2 C1=CC(=NC(=C1Cl)C(=O)O)Cl InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Salmonella typhimurium (as organism) TA1530 Not reported yes, concurrent vehicle without Negative RMS: Finland Clopyralid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid 23Jan2006 2006 doi: 10.2903/j.efsa.2006.50r
+Clopyralid 216-935-4 1702-17-6 single chemical entity Component is identical to the substance Clopyralid 216-935-4 1702-17-6 3,6-dichloropyridine-2-carboxylic acid Clopyralid C6H3Cl2NO2 C1=CC(=NC(=C1Cl)C(=O)O)Cl InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Rat (as animal) lymphocytes Not reported yes with Negative RMS: Finland Clopyralid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid 23Jan2006 2006 doi: 10.2903/j.efsa.2006.50r
+Clopyralid 216-935-4 1702-17-6 single chemical entity Component is identical to the substance Clopyralid 216-935-4 1702-17-6 3,6-dichloropyridine-2-carboxylic acid Clopyralid C6H3Cl2NO2 C1=CC(=NC(=C1Cl)C(=O)O)Cl InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Rat (as animal) lymphocytes Not reported yes with Negative RMS: Finland Clopyralid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid 23Jan2006 2006 doi: 10.2903/j.efsa.2006.50r
+Clopyralid 216-935-4 1702-17-6 single chemical entity Component is identical to the substance Clopyralid 216-935-4 1702-17-6 3,6-dichloropyridine-2-carboxylic acid Clopyralid C6H3Cl2NO2 C1=CC(=NC(=C1Cl)C(=O)O)Cl InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes not applicable Negative no evidence RMS: Finland Clopyralid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid 23Jan2006 2006 doi: 10.2903/j.efsa.2006.50r
+Clopyralid 216-935-4 1702-17-6 single chemical entity Component is identical to the substance Clopyralid 216-935-4 1702-17-6 3,6-dichloropyridine-2-carboxylic acid Clopyralid C6H3Cl2NO2 C1=CC(=NC(=C1Cl)C(=O)O)Cl InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 48.0000000000 h yes not applicable Negative no evidence RMS: Finland Clopyralid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid 23Jan2006 2006 doi: 10.2903/j.efsa.2006.50r
+Clopyralid 216-935-4 1702-17-6 single chemical entity Component is identical to the substance Clopyralid 216-935-4 1702-17-6 3,6-dichloropyridine-2-carboxylic acid Clopyralid C6H3Cl2NO2 C1=CC(=NC(=C1Cl)C(=O)O)Cl InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 72.0000000000 h yes not applicable Negative no evidence RMS: Finland Clopyralid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid 23Jan2006 2006 doi: 10.2903/j.efsa.2006.50r
+Clopyralid 216-935-4 1702-17-6 single chemical entity Component is identical to the substance Clopyralid 216-935-4 1702-17-6 3,6-dichloropyridine-2-carboxylic acid Clopyralid C6H3Cl2NO2 C1=CC(=NC(=C1Cl)C(=O)O)Cl InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Sprague-Dawley 5 Male oral: gavage 6.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Finland Clopyralid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid 23Jan2006 2006 doi: 10.2903/j.efsa.2006.50r
+Clopyralid 216-935-4 1702-17-6 single chemical entity Component is identical to the substance Clopyralid 216-935-4 1702-17-6 3,6-dichloropyridine-2-carboxylic acid Clopyralid C6H3Cl2NO2 C1=CC(=NC(=C1Cl)C(=O)O)Cl InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Sprague-Dawley 5 Male oral: gavage 5.0000000000 D yes, concurrent vehicle not applicable Negative RMS: Finland Clopyralid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid 23Jan2006 2006 doi: 10.2903/j.efsa.2006.50r
+Clopyralid 216-935-4 1702-17-6 single chemical entity Component is identical to the substance Clopyralid 216-935-4 1702-17-6 3,6-dichloropyridine-2-carboxylic acid Clopyralid C6H3Cl2NO2 C1=CC(=NC(=C1Cl)C(=O)O)Cl InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Sprague-Dawley 5 Male oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Finland Clopyralid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid 23Jan2006 2006 doi: 10.2903/j.efsa.2006.50r
+Clopyralid 216-935-4 1702-17-6 single chemical entity Component is identical to the substance Clopyralid 216-935-4 1702-17-6 3,6-dichloropyridine-2-carboxylic acid Clopyralid C6H3Cl2NO2 C1=CC(=NC(=C1Cl)C(=O)O)Cl InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Sprague-Dawley 5 Male oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Finland Clopyralid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid 23Jan2006 2006 doi: 10.2903/j.efsa.2006.50r
+Clopyralid 216-935-4 1702-17-6 single chemical entity Component is identical to the substance Clopyralid 216-935-4 1702-17-6 3,6-dichloropyridine-2-carboxylic acid Clopyralid C6H3Cl2NO2 C1=CC(=NC(=C1Cl)C(=O)O)Cl InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) Yes Acceptable Rat (as animal) Sprague-Dawley 10 Male oral: gavage 5.0000000000 D yes, concurrent vehicle not applicable Negative RMS: Finland Clopyralid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid 23Jan2006 2006 doi: 10.2903/j.efsa.2006.50r
+Cyhalofop-butyl 601-817-0 122008-85-9 single chemical entity Component is identical to the substance Cyhalofop-butyl 601-817-0 122008-85-9 butyl (2R)-2-[4-(4-cyano-2-fluorophenoxy)phenoxy]propanoate Cyhalofop-butyl (sum of cyhalofop butyl and its free acids) C20H20FNO4 CCCCOC(=O)C(C)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)C#N)F InChI=1S/C20H20FNO4/c1-3-4-11-24-20(23)14(2)25-16-6-8-17(9-7-16)26-19-10-5-15(13-22)12-18(19)21/h5-10,12,14H,3-4,11H2,1-2H3/t14-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Italy Cyhalofop-butyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl) 30Jan2015 2015 doi: 10.2903/j.efsa.2015.3943
+Cyhalofop-butyl 601-817-0 122008-85-9 single chemical entity Component is identical to the substance Cyhalofop-butyl 601-817-0 122008-85-9 butyl (2R)-2-[4-(4-cyano-2-fluorophenoxy)phenoxy]propanoate Cyhalofop-butyl (sum of cyhalofop butyl and its free acids) C20H20FNO4 CCCCOC(=O)C(C)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)C#N)F InChI=1S/C20H20FNO4/c1-3-4-11-24-20(23)14(2)25-16-6-8-17(9-7-16)26-19-10-5-15(13-22)12-18(19)21/h5-10,12,14H,3-4,11H2,1-2H3/t14-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Italy Cyhalofop-butyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl) 30Jan2015 2015 doi: 10.2903/j.efsa.2015.3943
+Cyhalofop-butyl 601-817-0 122008-85-9 single chemical entity Component is identical to the substance Cyhalofop-butyl 601-817-0 122008-85-9 butyl (2R)-2-[4-(4-cyano-2-fluorophenoxy)phenoxy]propanoate Cyhalofop-butyl (sum of cyhalofop butyl and its free acids) C20H20FNO4 CCCCOC(=O)C(C)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)C#N)F InChI=1S/C20H20FNO4/c1-3-4-11-24-20(23)14(2)25-16-6-8-17(9-7-16)26-19-10-5-15(13-22)12-18(19)21/h5-10,12,14H,3-4,11H2,1-2H3/t14-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Italy Cyhalofop-butyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl) 30Jan2015 2015 doi: 10.2903/j.efsa.2015.3943
+Cyhalofop-butyl 601-817-0 122008-85-9 single chemical entity Component is identical to the substance Cyhalofop-butyl 601-817-0 122008-85-9 butyl (2R)-2-[4-(4-cyano-2-fluorophenoxy)phenoxy]propanoate Cyhalofop-butyl (sum of cyhalofop butyl and its free acids) C20H20FNO4 CCCCOC(=O)C(C)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)C#N)F InChI=1S/C20H20FNO4/c1-3-4-11-24-20(23)14(2)25-16-6-8-17(9-7-16)26-19-10-5-15(13-22)12-18(19)21/h5-10,12,14H,3-4,11H2,1-2H3/t14-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Italy Cyhalofop-butyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl) 30Jan2015 2015 doi: 10.2903/j.efsa.2015.3943
+Cyhalofop-butyl 601-817-0 122008-85-9 single chemical entity Component is identical to the substance Cyhalofop-butyl 601-817-0 122008-85-9 butyl (2R)-2-[4-(4-cyano-2-fluorophenoxy)phenoxy]propanoate Cyhalofop-butyl (sum of cyhalofop butyl and its free acids) C20H20FNO4 CCCCOC(=O)C(C)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)C#N)F InChI=1S/C20H20FNO4/c1-3-4-11-24-20(23)14(2)25-16-6-8-17(9-7-16)26-19-10-5-15(13-22)12-18(19)21/h5-10,12,14H,3-4,11H2,1-2H3/t14-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Italy Cyhalofop-butyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl) 30Jan2015 2015 doi: 10.2903/j.efsa.2015.3943
+Cyhalofop-butyl 601-817-0 122008-85-9 single chemical entity Component is identical to the substance Cyhalofop-butyl 601-817-0 122008-85-9 butyl (2R)-2-[4-(4-cyano-2-fluorophenoxy)phenoxy]propanoate Cyhalofop-butyl (sum of cyhalofop butyl and its free acids) C20H20FNO4 CCCCOC(=O)C(C)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)C#N)F InChI=1S/C20H20FNO4/c1-3-4-11-24-20(23)14(2)25-16-6-8-17(9-7-16)26-19-10-5-15(13-22)12-18(19)21/h5-10,12,14H,3-4,11H2,1-2H3/t14-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Italy Cyhalofop-butyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl) 30Jan2015 2015 doi: 10.2903/j.efsa.2015.3943
+Cyhalofop-butyl 601-817-0 122008-85-9 single chemical entity Component is identical to the substance Cyhalofop-butyl 601-817-0 122008-85-9 butyl (2R)-2-[4-(4-cyano-2-fluorophenoxy)phenoxy]propanoate Cyhalofop-butyl (sum of cyhalofop butyl and its free acids) C20H20FNO4 CCCCOC(=O)C(C)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)C#N)F InChI=1S/C20H20FNO4/c1-3-4-11-24-20(23)14(2)25-16-6-8-17(9-7-16)26-19-10-5-15(13-22)12-18(19)21/h5-10,12,14H,3-4,11H2,1-2H3/t14-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Italy Cyhalofop-butyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl) 30Jan2015 2015 doi: 10.2903/j.efsa.2015.3943
+Cyhalofop-butyl 601-817-0 122008-85-9 single chemical entity Component is identical to the substance Cyhalofop-butyl 601-817-0 122008-85-9 butyl (2R)-2-[4-(4-cyano-2-fluorophenoxy)phenoxy]propanoate Cyhalofop-butyl (sum of cyhalofop butyl and its free acids) C20H20FNO4 CCCCOC(=O)C(C)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)C#N)F InChI=1S/C20H20FNO4/c1-3-4-11-24-20(23)14(2)25-16-6-8-17(9-7-16)26-19-10-5-15(13-22)12-18(19)21/h5-10,12,14H,3-4,11H2,1-2H3/t14-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Italy Cyhalofop-butyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl) 30Jan2015 2015 doi: 10.2903/j.efsa.2015.3943
+Cyhalofop-butyl 601-817-0 122008-85-9 single chemical entity Component is identical to the substance Cyhalofop-butyl 601-817-0 122008-85-9 butyl (2R)-2-[4-(4-cyano-2-fluorophenoxy)phenoxy]propanoate Cyhalofop-butyl (sum of cyhalofop butyl and its free acids) C20H20FNO4 CCCCOC(=O)C(C)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)C#N)F InChI=1S/C20H20FNO4/c1-3-4-11-24-20(23)14(2)25-16-6-8-17(9-7-16)26-19-10-5-15(13-22)12-18(19)21/h5-10,12,14H,3-4,11H2,1-2H3/t14-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Italy Cyhalofop-butyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl) 30Jan2015 2015 doi: 10.2903/j.efsa.2015.3943
+Cyhalofop-butyl 601-817-0 122008-85-9 single chemical entity Component is identical to the substance Cyhalofop-butyl 601-817-0 122008-85-9 butyl (2R)-2-[4-(4-cyano-2-fluorophenoxy)phenoxy]propanoate Cyhalofop-butyl (sum of cyhalofop butyl and its free acids) C20H20FNO4 CCCCOC(=O)C(C)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)C#N)F InChI=1S/C20H20FNO4/c1-3-4-11-24-20(23)14(2)25-16-6-8-17(9-7-16)26-19-10-5-15(13-22)12-18(19)21/h5-10,12,14H,3-4,11H2,1-2H3/t14-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Italy Cyhalofop-butyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl) 30Jan2015 2015 doi: 10.2903/j.efsa.2015.3943
+Cyhalofop-butyl 601-817-0 122008-85-9 single chemical entity Component is identical to the substance Cyhalofop-butyl 601-817-0 122008-85-9 butyl (2R)-2-[4-(4-cyano-2-fluorophenoxy)phenoxy]propanoate Cyhalofop-butyl (sum of cyhalofop butyl and its free acids) C20H20FNO4 CCCCOC(=O)C(C)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)C#N)F InChI=1S/C20H20FNO4/c1-3-4-11-24-20(23)14(2)25-16-6-8-17(9-7-16)26-19-10-5-15(13-22)12-18(19)21/h5-10,12,14H,3-4,11H2,1-2H3/t14-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Italy Cyhalofop-butyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl) 30Jan2015 2015 doi: 10.2903/j.efsa.2015.3943
+Cyhalofop-butyl 601-817-0 122008-85-9 single chemical entity Component is identical to the substance Cyhalofop-butyl 601-817-0 122008-85-9 butyl (2R)-2-[4-(4-cyano-2-fluorophenoxy)phenoxy]propanoate Cyhalofop-butyl (sum of cyhalofop butyl and its free acids) C20H20FNO4 CCCCOC(=O)C(C)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)C#N)F InChI=1S/C20H20FNO4/c1-3-4-11-24-20(23)14(2)25-16-6-8-17(9-7-16)26-19-10-5-15(13-22)12-18(19)21/h5-10,12,14H,3-4,11H2,1-2H3/t14-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Italy Cyhalofop-butyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl) 30Jan2015 2015 doi: 10.2903/j.efsa.2015.3943
+Cyhalofop-butyl 601-817-0 122008-85-9 single chemical entity Component is identical to the substance Cyhalofop-butyl 601-817-0 122008-85-9 butyl (2R)-2-[4-(4-cyano-2-fluorophenoxy)phenoxy]propanoate Cyhalofop-butyl (sum of cyhalofop butyl and its free acids) C20H20FNO4 CCCCOC(=O)C(C)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)C#N)F InChI=1S/C20H20FNO4/c1-3-4-11-24-20(23)14(2)25-16-6-8-17(9-7-16)26-19-10-5-15(13-22)12-18(19)21/h5-10,12,14H,3-4,11H2,1-2H3/t14-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes, concurrent vehicle without Negative RMS: Italy Cyhalofop-butyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl) 30Jan2015 2015 doi: 10.2903/j.efsa.2015.3943
+Cyhalofop-butyl 601-817-0 122008-85-9 single chemical entity Component is identical to the substance Cyhalofop-butyl 601-817-0 122008-85-9 butyl (2R)-2-[4-(4-cyano-2-fluorophenoxy)phenoxy]propanoate Cyhalofop-butyl (sum of cyhalofop butyl and its free acids) C20H20FNO4 CCCCOC(=O)C(C)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)C#N)F InChI=1S/C20H20FNO4/c1-3-4-11-24-20(23)14(2)25-16-6-8-17(9-7-16)26-19-10-5-15(13-22)12-18(19)21/h5-10,12,14H,3-4,11H2,1-2H3/t14-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes, concurrent vehicle without Negative RMS: Italy Cyhalofop-butyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl) 30Jan2015 2015 doi: 10.2903/j.efsa.2015.3943
+Cyhalofop-butyl 601-817-0 122008-85-9 single chemical entity Component is identical to the substance Cyhalofop-butyl 601-817-0 122008-85-9 butyl (2R)-2-[4-(4-cyano-2-fluorophenoxy)phenoxy]propanoate Cyhalofop-butyl (sum of cyhalofop butyl and its free acids) C20H20FNO4 CCCCOC(=O)C(C)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)C#N)F InChI=1S/C20H20FNO4/c1-3-4-11-24-20(23)14(2)25-16-6-8-17(9-7-16)26-19-10-5-15(13-22)12-18(19)21/h5-10,12,14H,3-4,11H2,1-2H3/t14-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes, concurrent vehicle with Negative RMS: Italy Cyhalofop-butyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl) 30Jan2015 2015 doi: 10.2903/j.efsa.2015.3943
+Cyhalofop-butyl 601-817-0 122008-85-9 single chemical entity Component is identical to the substance Cyhalofop-butyl 601-817-0 122008-85-9 butyl (2R)-2-[4-(4-cyano-2-fluorophenoxy)phenoxy]propanoate Cyhalofop-butyl (sum of cyhalofop butyl and its free acids) C20H20FNO4 CCCCOC(=O)C(C)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)C#N)F InChI=1S/C20H20FNO4/c1-3-4-11-24-20(23)14(2)25-16-6-8-17(9-7-16)26-19-10-5-15(13-22)12-18(19)21/h5-10,12,14H,3-4,11H2,1-2H3/t14-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes, concurrent vehicle with Negative RMS: Italy Cyhalofop-butyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl) 30Jan2015 2015 doi: 10.2903/j.efsa.2015.3943
+Cyhalofop-butyl 601-817-0 122008-85-9 single chemical entity Component is identical to the substance Cyhalofop-butyl 601-817-0 122008-85-9 butyl (2R)-2-[4-(4-cyano-2-fluorophenoxy)phenoxy]propanoate Cyhalofop-butyl (sum of cyhalofop butyl and its free acids) C20H20FNO4 CCCCOC(=O)C(C)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)C#N)F InChI=1S/C20H20FNO4/c1-3-4-11-24-20(23)14(2)25-16-6-8-17(9-7-16)26-19-10-5-15(13-22)12-18(19)21/h5-10,12,14H,3-4,11H2,1-2H3/t14-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Italy Cyhalofop-butyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl) 30Jan2015 2015 doi: 10.2903/j.efsa.2015.3943
+Cyhalofop-butyl 601-817-0 122008-85-9 single chemical entity Component is identical to the substance Cyhalofop-butyl 601-817-0 122008-85-9 butyl (2R)-2-[4-(4-cyano-2-fluorophenoxy)phenoxy]propanoate Cyhalofop-butyl (sum of cyhalofop butyl and its free acids) C20H20FNO4 CCCCOC(=O)C(C)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)C#N)F InChI=1S/C20H20FNO4/c1-3-4-11-24-20(23)14(2)25-16-6-8-17(9-7-16)26-19-10-5-15(13-22)12-18(19)21/h5-10,12,14H,3-4,11H2,1-2H3/t14-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Italy Cyhalofop-butyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl) 30Jan2015 2015 doi: 10.2903/j.efsa.2015.3943
+Cyhalofop-butyl 601-817-0 122008-85-9 single chemical entity Component is identical to the substance Cyhalofop-butyl 601-817-0 122008-85-9 butyl (2R)-2-[4-(4-cyano-2-fluorophenoxy)phenoxy]propanoate Cyhalofop-butyl (sum of cyhalofop butyl and its free acids) C20H20FNO4 CCCCOC(=O)C(C)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)C#N)F InChI=1S/C20H20FNO4/c1-3-4-11-24-20(23)14(2)25-16-6-8-17(9-7-16)26-19-10-5-15(13-22)12-18(19)21/h5-10,12,14H,3-4,11H2,1-2H3/t14-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 72.0000000000 h yes not applicable Negative no evidence RMS: Italy Cyhalofop-butyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl) 30Jan2015 2015 doi: 10.2903/j.efsa.2015.3943
+Cyhalofop-butyl 601-817-0 122008-85-9 single chemical entity Component is identical to the substance Cyhalofop-butyl 601-817-0 122008-85-9 butyl (2R)-2-[4-(4-cyano-2-fluorophenoxy)phenoxy]propanoate Cyhalofop-butyl (sum of cyhalofop butyl and its free acids) C20H20FNO4 CCCCOC(=O)C(C)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)C#N)F InChI=1S/C20H20FNO4/c1-3-4-11-24-20(23)14(2)25-16-6-8-17(9-7-16)26-19-10-5-15(13-22)12-18(19)21/h5-10,12,14H,3-4,11H2,1-2H3/t14-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 48.0000000000 h yes not applicable Negative no evidence RMS: Italy Cyhalofop-butyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl) 30Jan2015 2015 doi: 10.2903/j.efsa.2015.3943
+Cyhalofop-butyl 601-817-0 122008-85-9 single chemical entity Component is identical to the substance Cyhalofop-butyl 601-817-0 122008-85-9 butyl (2R)-2-[4-(4-cyano-2-fluorophenoxy)phenoxy]propanoate Cyhalofop-butyl (sum of cyhalofop butyl and its free acids) C20H20FNO4 CCCCOC(=O)C(C)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)C#N)F InChI=1S/C20H20FNO4/c1-3-4-11-24-20(23)14(2)25-16-6-8-17(9-7-16)26-19-10-5-15(13-22)12-18(19)21/h5-10,12,14H,3-4,11H2,1-2H3/t14-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes not applicable Negative no evidence RMS: Italy Cyhalofop-butyl 1998 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl) 30Jan2015 2015 doi: 10.2903/j.efsa.2015.3943
+Diflubenzuron 252-529-3 35367-38-5 single chemical entity Component is identical to the substance Diflubenzuron 252-529-3 35367-38-5 N-[(4-chlorophenyl)carbamoyl]-2,6-difluorobenzamide Diflubenzuron C14H9ClF2N2O2 Fc1cccc(F)c1C(=O)NC(=O)Nc2ccc(Cl)cc2 InChI=1/C14H9ClF2N2O2/c15-8-4-6-9(7-5-8)18-14(21)19-13(20)12-10(16)2-1-3-11(12)17/h1-7H,(H2,18,19,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Sweden Diflubenzuron (Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance diflubenzuron 07Sep2012 2012 doi:10.2903/j.efsa.2012.2870
+Diflubenzuron 252-529-3 35367-38-5 single chemical entity Component is identical to the substance Diflubenzuron 252-529-3 35367-38-5 N-[(4-chlorophenyl)carbamoyl]-2,6-difluorobenzamide Diflubenzuron C14H9ClF2N2O2 Fc1cccc(F)c1C(=O)NC(=O)Nc2ccc(Cl)cc2 InChI=1/C14H9ClF2N2O2/c15-8-4-6-9(7-5-8)18-14(21)19-13(20)12-10(16)2-1-3-11(12)17/h1-7H,(H2,18,19,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: Sweden Diflubenzuron (Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance diflubenzuron 07Sep2012 2012 doi:10.2903/j.efsa.2012.2870
+Diflubenzuron 252-529-3 35367-38-5 single chemical entity Component is identical to the substance Diflubenzuron 252-529-3 35367-38-5 N-[(4-chlorophenyl)carbamoyl]-2,6-difluorobenzamide Diflubenzuron C14H9ClF2N2O2 Fc1cccc(F)c1C(=O)NC(=O)Nc2ccc(Cl)cc2 InChI=1/C14H9ClF2N2O2/c15-8-4-6-9(7-5-8)18-14(21)19-13(20)12-10(16)2-1-3-11(12)17/h1-7H,(H2,18,19,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: Sweden Diflubenzuron (Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance diflubenzuron 07Sep2012 2012 doi:10.2903/j.efsa.2012.2870
+Diflubenzuron 252-529-3 35367-38-5 single chemical entity Component is identical to the substance Diflubenzuron 252-529-3 35367-38-5 N-[(4-chlorophenyl)carbamoyl]-2,6-difluorobenzamide Diflubenzuron C14H9ClF2N2O2 Fc1cccc(F)c1C(=O)NC(=O)Nc2ccc(Cl)cc2 InChI=1/C14H9ClF2N2O2/c15-8-4-6-9(7-5-8)18-14(21)19-13(20)12-10(16)2-1-3-11(12)17/h1-7H,(H2,18,19,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Sweden Diflubenzuron (Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance diflubenzuron 07Sep2012 2012 doi:10.2903/j.efsa.2012.2870
+Diflubenzuron 252-529-3 35367-38-5 single chemical entity Component is identical to the substance Diflubenzuron 252-529-3 35367-38-5 N-[(4-chlorophenyl)carbamoyl]-2,6-difluorobenzamide Diflubenzuron C14H9ClF2N2O2 Fc1cccc(F)c1C(=O)NC(=O)Nc2ccc(Cl)cc2 InChI=1/C14H9ClF2N2O2/c15-8-4-6-9(7-5-8)18-14(21)19-13(20)12-10(16)2-1-3-11(12)17/h1-7H,(H2,18,19,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Sweden Diflubenzuron (Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance diflubenzuron 07Sep2012 2012 doi:10.2903/j.efsa.2012.2870
+Diflubenzuron 252-529-3 35367-38-5 single chemical entity Component is identical to the substance Diflubenzuron 252-529-3 35367-38-5 N-[(4-chlorophenyl)carbamoyl]-2,6-difluorobenzamide Diflubenzuron C14H9ClF2N2O2 Fc1cccc(F)c1C(=O)NC(=O)Nc2ccc(Cl)cc2 InChI=1/C14H9ClF2N2O2/c15-8-4-6-9(7-5-8)18-14(21)19-13(20)12-10(16)2-1-3-11(12)17/h1-7H,(H2,18,19,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Sweden Diflubenzuron (Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance diflubenzuron 07Sep2012 2012 doi:10.2903/j.efsa.2012.2870
+Diflubenzuron 252-529-3 35367-38-5 single chemical entity Component is identical to the substance Diflubenzuron 252-529-3 35367-38-5 N-[(4-chlorophenyl)carbamoyl]-2,6-difluorobenzamide Diflubenzuron C14H9ClF2N2O2 Fc1cccc(F)c1C(=O)NC(=O)Nc2ccc(Cl)cc2 InChI=1/C14H9ClF2N2O2/c15-8-4-6-9(7-5-8)18-14(21)19-13(20)12-10(16)2-1-3-11(12)17/h1-7H,(H2,18,19,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Sweden Diflubenzuron (Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance diflubenzuron 07Sep2012 2012 doi:10.2903/j.efsa.2012.2870
+Diflubenzuron 252-529-3 35367-38-5 single chemical entity Component is identical to the substance Diflubenzuron 252-529-3 35367-38-5 N-[(4-chlorophenyl)carbamoyl]-2,6-difluorobenzamide Diflubenzuron C14H9ClF2N2O2 Fc1cccc(F)c1C(=O)NC(=O)Nc2ccc(Cl)cc2 InChI=1/C14H9ClF2N2O2/c15-8-4-6-9(7-5-8)18-14(21)19-13(20)12-10(16)2-1-3-11(12)17/h1-7H,(H2,18,19,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Sweden Diflubenzuron (Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance diflubenzuron 07Sep2012 2012 doi:10.2903/j.efsa.2012.2870
+Diflubenzuron 252-529-3 35367-38-5 single chemical entity Component is identical to the substance Diflubenzuron 252-529-3 35367-38-5 N-[(4-chlorophenyl)carbamoyl]-2,6-difluorobenzamide Diflubenzuron C14H9ClF2N2O2 Fc1cccc(F)c1C(=O)NC(=O)Nc2ccc(Cl)cc2 InChI=1/C14H9ClF2N2O2/c15-8-4-6-9(7-5-8)18-14(21)19-13(20)12-10(16)2-1-3-11(12)17/h1-7H,(H2,18,19,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Sweden Diflubenzuron (Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance diflubenzuron 07Sep2012 2012 doi:10.2903/j.efsa.2012.2870
+Diflubenzuron 252-529-3 35367-38-5 single chemical entity Component is identical to the substance Diflubenzuron 252-529-3 35367-38-5 N-[(4-chlorophenyl)carbamoyl]-2,6-difluorobenzamide Diflubenzuron C14H9ClF2N2O2 Fc1cccc(F)c1C(=O)NC(=O)Nc2ccc(Cl)cc2 InChI=1/C14H9ClF2N2O2/c15-8-4-6-9(7-5-8)18-14(21)19-13(20)12-10(16)2-1-3-11(12)17/h1-7H,(H2,18,19,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Sweden Diflubenzuron (Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance diflubenzuron 07Sep2012 2012 doi:10.2903/j.efsa.2012.2870
+Diflubenzuron 252-529-3 35367-38-5 single chemical entity Component is identical to the substance Diflubenzuron 252-529-3 35367-38-5 N-[(4-chlorophenyl)carbamoyl]-2,6-difluorobenzamide Diflubenzuron C14H9ClF2N2O2 Fc1cccc(F)c1C(=O)NC(=O)Nc2ccc(Cl)cc2 InChI=1/C14H9ClF2N2O2/c15-8-4-6-9(7-5-8)18-14(21)19-13(20)12-10(16)2-1-3-11(12)17/h1-7H,(H2,18,19,20,21) organic compound Other Other DNA damage and/or repair in vitro mammalian cell transformation assay in vitro No guideline available Not reported Not applicable Acceptable House mouse (as animal) 3T3 Not reported yes, concurrent vehicle without Negative RMS: Sweden Diflubenzuron (Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance diflubenzuron 07Sep2012 2012 doi:10.2903/j.efsa.2012.2870
+Diflubenzuron 252-529-3 35367-38-5 single chemical entity Component is identical to the substance Diflubenzuron 252-529-3 35367-38-5 N-[(4-chlorophenyl)carbamoyl]-2,6-difluorobenzamide Diflubenzuron C14H9ClF2N2O2 Fc1cccc(F)c1C(=O)NC(=O)Nc2ccc(Cl)cc2 InChI=1/C14H9ClF2N2O2/c15-8-4-6-9(7-5-8)18-14(21)19-13(20)12-10(16)2-1-3-11(12)17/h1-7H,(H2,18,19,20,21) organic compound Other Other DNA damage and/or repair in vitro mammalian cell transformation assay in vitro No guideline available Not reported Not applicable Acceptable House mouse (as animal) 3T3 Not reported yes, concurrent vehicle with Negative RMS: Sweden Diflubenzuron (Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance diflubenzuron 07Sep2012 2012 doi:10.2903/j.efsa.2012.2870
+Diflubenzuron 252-529-3 35367-38-5 single chemical entity Component is identical to the substance Diflubenzuron 252-529-3 35367-38-5 N-[(4-chlorophenyl)carbamoyl]-2,6-difluorobenzamide Diflubenzuron C14H9ClF2N2O2 Fc1cccc(F)c1C(=O)NC(=O)Nc2ccc(Cl)cc2 InChI=1/C14H9ClF2N2O2/c15-8-4-6-9(7-5-8)18-14(21)19-13(20)12-10(16)2-1-3-11(12)17/h1-7H,(H2,18,19,20,21) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: Sweden Diflubenzuron (Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance diflubenzuron 07Sep2012 2012 doi:10.2903/j.efsa.2012.2870
+Diflubenzuron 252-529-3 35367-38-5 single chemical entity Component is identical to the substance Diflubenzuron 252-529-3 35367-38-5 N-[(4-chlorophenyl)carbamoyl]-2,6-difluorobenzamide Diflubenzuron C14H9ClF2N2O2 Fc1cccc(F)c1C(=O)NC(=O)Nc2ccc(Cl)cc2 InChI=1/C14H9ClF2N2O2/c15-8-4-6-9(7-5-8)18-14(21)19-13(20)12-10(16)2-1-3-11(12)17/h1-7H,(H2,18,19,20,21) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: Sweden Diflubenzuron (Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance diflubenzuron 07Sep2012 2012 doi:10.2903/j.efsa.2012.2870
+Diflubenzuron 252-529-3 35367-38-5 single chemical entity Component is identical to the substance Diflubenzuron 252-529-3 35367-38-5 N-[(4-chlorophenyl)carbamoyl]-2,6-difluorobenzamide Diflubenzuron C14H9ClF2N2O2 Fc1cccc(F)c1C(=O)NC(=O)Nc2ccc(Cl)cc2 InChI=1/C14H9ClF2N2O2/c15-8-4-6-9(7-5-8)18-14(21)19-13(20)12-10(16)2-1-3-11(12)17/h1-7H,(H2,18,19,20,21) organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Sweden Diflubenzuron (Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance diflubenzuron 07Sep2012 2012 doi:10.2903/j.efsa.2012.2870
+Diflubenzuron 252-529-3 35367-38-5 single chemical entity Component is identical to the substance Diflubenzuron 252-529-3 35367-38-5 N-[(4-chlorophenyl)carbamoyl]-2,6-difluorobenzamide Diflubenzuron C14H9ClF2N2O2 Fc1cccc(F)c1C(=O)NC(=O)Nc2ccc(Cl)cc2 InChI=1/C14H9ClF2N2O2/c15-8-4-6-9(7-5-8)18-14(21)19-13(20)12-10(16)2-1-3-11(12)17/h1-7H,(H2,18,19,20,21) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) SwissWebster 5 Male oral: unspecified 30.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Sweden Diflubenzuron (Addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance diflubenzuron 07Sep2012 2012 doi:10.2903/j.efsa.2012.2870
+Carbetamide 240-286-6 16118-49-3 single chemical entity Component is a metabolite of the substance (RS) 2-phenylcarbamoyl-propionic acid {2-[(phenylcarbamoyl)oxy]propanoyl}carbamic acid Not in list C11H12N2O5 O=C(O)NC(=O)C(C)OC(=O)Nc1ccccc1 InChI=1/C11H12N2O5/c1-7(9(14)13-10(15)16)18-11(17)12-8-5-3-2-4-6-8/h2-7H,1H3,(H,12,17)(H,13,14)(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Carbetamide (Revised DAR of December 2005) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1913
+Carbetamide 240-286-6 16118-49-3 single chemical entity Component is a metabolite of the substance (RS) 2-phenylcarbamoyl-propionic acid {2-[(phenylcarbamoyl)oxy]propanoyl}carbamic acid Not in list C11H12N2O5 O=C(O)NC(=O)C(C)OC(=O)Nc1ccccc1 InChI=1/C11H12N2O5/c1-7(9(14)13-10(15)16)18-11(17)12-8-5-3-2-4-6-8/h2-7H,1H3,(H,12,17)(H,13,14)(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Carbetamide (Revised DAR of December 2005) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1913
+Carbetamide 240-286-6 16118-49-3 single chemical entity Component is a metabolite of the substance (RS) 2-phenylcarbamoyl-propionic acid {2-[(phenylcarbamoyl)oxy]propanoyl}carbamic acid Not in list C11H12N2O5 O=C(O)NC(=O)C(C)OC(=O)Nc1ccccc1 InChI=1/C11H12N2O5/c1-7(9(14)13-10(15)16)18-11(17)12-8-5-3-2-4-6-8/h2-7H,1H3,(H,12,17)(H,13,14)(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Carbetamide (Revised DAR of December 2005) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1913
+Carbetamide 240-286-6 16118-49-3 single chemical entity Component is a metabolite of the substance (RS) 2-phenylcarbamoyl-propionic acid {2-[(phenylcarbamoyl)oxy]propanoyl}carbamic acid Not in list C11H12N2O5 O=C(O)NC(=O)C(C)OC(=O)Nc1ccccc1 InChI=1/C11H12N2O5/c1-7(9(14)13-10(15)16)18-11(17)12-8-5-3-2-4-6-8/h2-7H,1H3,(H,12,17)(H,13,14)(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Carbetamide (Revised DAR of December 2005) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1913
+Carbetamide 240-286-6 16118-49-3 single chemical entity Component is a metabolite of the substance (RS) 2-phenylcarbamoyl-propionic acid {2-[(phenylcarbamoyl)oxy]propanoyl}carbamic acid Not in list C11H12N2O5 O=C(O)NC(=O)C(C)OC(=O)Nc1ccccc1 InChI=1/C11H12N2O5/c1-7(9(14)13-10(15)16)18-11(17)12-8-5-3-2-4-6-8/h2-7H,1H3,(H,12,17)(H,13,14)(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Carbetamide (Revised DAR of December 2005) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1913
+Carbetamide 240-286-6 16118-49-3 single chemical entity Component is a metabolite of the substance (RS) 2-phenylcarbamoyl-propionic acid {2-[(phenylcarbamoyl)oxy]propanoyl}carbamic acid Not in list C11H12N2O5 O=C(O)NC(=O)C(C)OC(=O)Nc1ccccc1 InChI=1/C11H12N2O5/c1-7(9(14)13-10(15)16)18-11(17)12-8-5-3-2-4-6-8/h2-7H,1H3,(H,12,17)(H,13,14)(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: France Carbetamide (Revised DAR of December 2005) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1913
+Carbetamide 240-286-6 16118-49-3 single chemical entity Component is a metabolite of the substance (RS) 2-phenylcarbamoyl-propionic acid {2-[(phenylcarbamoyl)oxy]propanoyl}carbamic acid Not in list C11H12N2O5 O=C(O)NC(=O)C(C)OC(=O)Nc1ccccc1 InChI=1/C11H12N2O5/c1-7(9(14)13-10(15)16)18-11(17)12-8-5-3-2-4-6-8/h2-7H,1H3,(H,12,17)(H,13,14)(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Carbetamide (Revised DAR of December 2005) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1913
+Carbetamide 240-286-6 16118-49-3 single chemical entity Component is a metabolite of the substance (RS) 2-phenylcarbamoyl-propionic acid {2-[(phenylcarbamoyl)oxy]propanoyl}carbamic acid Not in list C11H12N2O5 O=C(O)NC(=O)C(C)OC(=O)Nc1ccccc1 InChI=1/C11H12N2O5/c1-7(9(14)13-10(15)16)18-11(17)12-8-5-3-2-4-6-8/h2-7H,1H3,(H,12,17)(H,13,14)(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Carbetamide (Revised DAR of December 2005) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1913
+Carbetamide 240-286-6 16118-49-3 single chemical entity Component is a metabolite of the substance (RS) 2-phenylcarbamoyl-propionic acid {2-[(phenylcarbamoyl)oxy]propanoyl}carbamic acid Not in list C11H12N2O5 O=C(O)NC(=O)C(C)OC(=O)Nc1ccccc1 InChI=1/C11H12N2O5/c1-7(9(14)13-10(15)16)18-11(17)12-8-5-3-2-4-6-8/h2-7H,1H3,(H,12,17)(H,13,14)(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Carbetamide (Revised DAR of December 2005) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1913
+Carbetamide 240-286-6 16118-49-3 single chemical entity Component is a metabolite of the substance (RS) 2-phenylcarbamoyl-propionic acid {2-[(phenylcarbamoyl)oxy]propanoyl}carbamic acid Not in list C11H12N2O5 O=C(O)NC(=O)C(C)OC(=O)Nc1ccccc1 InChI=1/C11H12N2O5/c1-7(9(14)13-10(15)16)18-11(17)12-8-5-3-2-4-6-8/h2-7H,1H3,(H,12,17)(H,13,14)(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: France Carbetamide (Revised DAR of December 2005) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1913
+Carboxin 226-031-1 5234-68-4 single chemical entity Component is identical to the substance Carboxin 226-031-1 5234-68-4 2-methyl-N-phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide Carboxin C12H13NO2S CC1=C(SCCO1)C(=O)Nc2ccccc2 InChI=1/C12H13NO2S/c1-9-11(16-8-7-15-9)12(14)13-10-5-3-2-4-6-10/h2-6H,7-8H2,1H3,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Carboxin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin 18Oct2010 2010 doi:10.2903/j.efsa.2010.1857
+Carboxin 226-031-1 5234-68-4 single chemical entity Component is identical to the substance Carboxin 226-031-1 5234-68-4 2-methyl-N-phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide Carboxin C12H13NO2S CC1=C(SCCO1)C(=O)Nc2ccccc2 InChI=1/C12H13NO2S/c1-9-11(16-8-7-15-9)12(14)13-10-5-3-2-4-6-10/h2-6H,7-8H2,1H3,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Carboxin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin 18Oct2010 2010 doi:10.2903/j.efsa.2010.1857
+Carboxin 226-031-1 5234-68-4 single chemical entity Component is identical to the substance Carboxin 226-031-1 5234-68-4 2-methyl-N-phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide Carboxin C12H13NO2S CC1=C(SCCO1)C(=O)Nc2ccccc2 InChI=1/C12H13NO2S/c1-9-11(16-8-7-15-9)12(14)13-10-5-3-2-4-6-10/h2-6H,7-8H2,1H3,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Carboxin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin 18Oct2010 2010 doi:10.2903/j.efsa.2010.1857
+Carboxin 226-031-1 5234-68-4 single chemical entity Component is identical to the substance Carboxin 226-031-1 5234-68-4 2-methyl-N-phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide Carboxin C12H13NO2S CC1=C(SCCO1)C(=O)Nc2ccccc2 InChI=1/C12H13NO2S/c1-9-11(16-8-7-15-9)12(14)13-10-5-3-2-4-6-10/h2-6H,7-8H2,1H3,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Carboxin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin 18Oct2010 2010 doi:10.2903/j.efsa.2010.1857
+Carboxin 226-031-1 5234-68-4 single chemical entity Component is identical to the substance Carboxin 226-031-1 5234-68-4 2-methyl-N-phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide Carboxin C12H13NO2S CC1=C(SCCO1)C(=O)Nc2ccccc2 InChI=1/C12H13NO2S/c1-9-11(16-8-7-15-9)12(14)13-10-5-3-2-4-6-10/h2-6H,7-8H2,1H3,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Carboxin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin 18Oct2010 2010 doi:10.2903/j.efsa.2010.1857
+Carboxin 226-031-1 5234-68-4 single chemical entity Component is identical to the substance Carboxin 226-031-1 5234-68-4 2-methyl-N-phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide Carboxin C12H13NO2S CC1=C(SCCO1)C(=O)Nc2ccccc2 InChI=1/C12H13NO2S/c1-9-11(16-8-7-15-9)12(14)13-10-5-3-2-4-6-10/h2-6H,7-8H2,1H3,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Carboxin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin 18Oct2010 2010 doi:10.2903/j.efsa.2010.1857
+Carboxin 226-031-1 5234-68-4 single chemical entity Component is identical to the substance Carboxin 226-031-1 5234-68-4 2-methyl-N-phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide Carboxin C12H13NO2S CC1=C(SCCO1)C(=O)Nc2ccccc2 InChI=1/C12H13NO2S/c1-9-11(16-8-7-15-9)12(14)13-10-5-3-2-4-6-10/h2-6H,7-8H2,1H3,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Carboxin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin 18Oct2010 2010 doi:10.2903/j.efsa.2010.1857
+Carboxin 226-031-1 5234-68-4 single chemical entity Component is identical to the substance Carboxin 226-031-1 5234-68-4 2-methyl-N-phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide Carboxin C12H13NO2S CC1=C(SCCO1)C(=O)Nc2ccccc2 InChI=1/C12H13NO2S/c1-9-11(16-8-7-15-9)12(14)13-10-5-3-2-4-6-10/h2-6H,7-8H2,1H3,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Carboxin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin 18Oct2010 2010 doi:10.2903/j.efsa.2010.1857
+Carboxin 226-031-1 5234-68-4 single chemical entity Component is identical to the substance Carboxin 226-031-1 5234-68-4 2-methyl-N-phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide Carboxin C12H13NO2S CC1=C(SCCO1)C(=O)Nc2ccccc2 InChI=1/C12H13NO2S/c1-9-11(16-8-7-15-9)12(14)13-10-5-3-2-4-6-10/h2-6H,7-8H2,1H3,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Carboxin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin 18Oct2010 2010 doi:10.2903/j.efsa.2010.1857
+Carboxin 226-031-1 5234-68-4 single chemical entity Component is identical to the substance Carboxin 226-031-1 5234-68-4 2-methyl-N-phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide Carboxin C12H13NO2S CC1=C(SCCO1)C(=O)Nc2ccccc2 InChI=1/C12H13NO2S/c1-9-11(16-8-7-15-9)12(14)13-10-5-3-2-4-6-10/h2-6H,7-8H2,1H3,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Carboxin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin 18Oct2010 2010 doi:10.2903/j.efsa.2010.1857
+Carboxin 226-031-1 5234-68-4 single chemical entity Component is identical to the substance Carboxin 226-031-1 5234-68-4 2-methyl-N-phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide Carboxin C12H13NO2S CC1=C(SCCO1)C(=O)Nc2ccccc2 InChI=1/C12H13NO2S/c1-9-11(16-8-7-15-9)12(14)13-10-5-3-2-4-6-10/h2-6H,7-8H2,1H3,(H,13,14) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Carboxin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin 18Oct2010 2010 doi:10.2903/j.efsa.2010.1857
+Carboxin 226-031-1 5234-68-4 single chemical entity Component is identical to the substance Carboxin 226-031-1 5234-68-4 2-methyl-N-phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide Carboxin C12H13NO2S CC1=C(SCCO1)C(=O)Nc2ccccc2 InChI=1/C12H13NO2S/c1-9-11(16-8-7-15-9)12(14)13-10-5-3-2-4-6-10/h2-6H,7-8H2,1H3,(H,13,14) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Carboxin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin 18Oct2010 2010 doi:10.2903/j.efsa.2010.1857
+Carboxin 226-031-1 5234-68-4 single chemical entity Component is identical to the substance Carboxin 226-031-1 5234-68-4 2-methyl-N-phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide Carboxin C12H13NO2S CC1=C(SCCO1)C(=O)Nc2ccccc2 InChI=1/C12H13NO2S/c1-9-11(16-8-7-15-9)12(14)13-10-5-3-2-4-6-10/h2-6H,7-8H2,1H3,(H,13,14) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: The United Kingdom Carboxin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin 18Oct2010 2010 doi:10.2903/j.efsa.2010.1857
+Carboxin 226-031-1 5234-68-4 single chemical entity Component is identical to the substance Carboxin 226-031-1 5234-68-4 2-methyl-N-phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide Carboxin C12H13NO2S CC1=C(SCCO1)C(=O)Nc2ccccc2 InChI=1/C12H13NO2S/c1-9-11(16-8-7-15-9)12(14)13-10-5-3-2-4-6-10/h2-6H,7-8H2,1H3,(H,13,14) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes with Positive RMS: The United Kingdom Carboxin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin 18Oct2010 2010 doi:10.2903/j.efsa.2010.1857
+Carboxin 226-031-1 5234-68-4 single chemical entity Component is identical to the substance Carboxin 226-031-1 5234-68-4 2-methyl-N-phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide Carboxin C12H13NO2S CC1=C(SCCO1)C(=O)Nc2ccccc2 InChI=1/C12H13NO2S/c1-9-11(16-8-7-15-9)12(14)13-10-5-3-2-4-6-10/h2-6H,7-8H2,1H3,(H,13,14) organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Positive RMS: The United Kingdom Carboxin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin 18Oct2010 2010 doi:10.2903/j.efsa.2010.1857
+Carboxin 226-031-1 5234-68-4 single chemical entity Component is identical to the substance Carboxin 226-031-1 5234-68-4 2-methyl-N-phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide Carboxin C12H13NO2S CC1=C(SCCO1)C(=O)Nc2ccccc2 InChI=1/C12H13NO2S/c1-9-11(16-8-7-15-9)12(14)13-10-5-3-2-4-6-10/h2-6H,7-8H2,1H3,(H,13,14) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable Rat (as animal) Sprague-Dawley 40 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: The United Kingdom Carboxin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin 18Oct2010 2010 doi:10.2903/j.efsa.2010.1857
+Carboxin 226-031-1 5234-68-4 single chemical entity Component is identical to the substance Carboxin 226-031-1 5234-68-4 2-methyl-N-phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide Carboxin C12H13NO2S CC1=C(SCCO1)C(=O)Nc2ccccc2 InChI=1/C12H13NO2S/c1-9-11(16-8-7-15-9)12(14)13-10-5-3-2-4-6-10/h2-6H,7-8H2,1H3,(H,13,14) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable Rat (as animal) Sprague-Dawley 40 Male/Female oral: gavage 6.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: The United Kingdom Carboxin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin 18Oct2010 2010 doi:10.2903/j.efsa.2010.1857
+Carboxin 226-031-1 5234-68-4 single chemical entity Component is identical to the substance Carboxin 226-031-1 5234-68-4 2-methyl-N-phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide Carboxin C12H13NO2S CC1=C(SCCO1)C(=O)Nc2ccccc2 InChI=1/C12H13NO2S/c1-9-11(16-8-7-15-9)12(14)13-10-5-3-2-4-6-10/h2-6H,7-8H2,1H3,(H,13,14) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable Rat (as animal) Sprague-Dawley 40 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: The United Kingdom Carboxin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin 18Oct2010 2010 doi:10.2903/j.efsa.2010.1857
+Carboxin 226-031-1 5234-68-4 single chemical entity Component is identical to the substance Carboxin 226-031-1 5234-68-4 2-methyl-N-phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide Carboxin C12H13NO2S CC1=C(SCCO1)C(=O)Nc2ccccc2 InChI=1/C12H13NO2S/c1-9-11(16-8-7-15-9)12(14)13-10-5-3-2-4-6-10/h2-6H,7-8H2,1H3,(H,13,14) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable Rat (as animal) Sprague-Dawley 40 Male/Female oral: gavage 12.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: The United Kingdom Carboxin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin 18Oct2010 2010 doi:10.2903/j.efsa.2010.1857
+Carboxin 226-031-1 5234-68-4 single chemical entity Component is identical to the substance Carboxin 226-031-1 5234-68-4 2-methyl-N-phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide Carboxin C12H13NO2S CC1=C(SCCO1)C(=O)Nc2ccccc2 InChI=1/C12H13NO2S/c1-9-11(16-8-7-15-9)12(14)13-10-5-3-2-4-6-10/h2-6H,7-8H2,1H3,(H,13,14) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable Rat (as animal) Sprague-Dawley 40 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: The United Kingdom Carboxin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin 18Oct2010 2010 doi:10.2903/j.efsa.2010.1857
+Carboxin 226-031-1 5234-68-4 single chemical entity Component is identical to the substance Carboxin 226-031-1 5234-68-4 2-methyl-N-phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide Carboxin C12H13NO2S CC1=C(SCCO1)C(=O)Nc2ccccc2 InChI=1/C12H13NO2S/c1-9-11(16-8-7-15-9)12(14)13-10-5-3-2-4-6-10/h2-6H,7-8H2,1H3,(H,13,14) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable Rat (as animal) Sprague-Dawley 40 Male/Female oral: gavage 12.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: The United Kingdom Carboxin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin 18Oct2010 2010 doi:10.2903/j.efsa.2010.1857
+Carboxin 226-031-1 5234-68-4 single chemical entity Component is identical to the substance Carboxin 226-031-1 5234-68-4 2-methyl-N-phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide Carboxin C12H13NO2S CC1=C(SCCO1)C(=O)Nc2ccccc2 InChI=1/C12H13NO2S/c1-9-11(16-8-7-15-9)12(14)13-10-5-3-2-4-6-10/h2-6H,7-8H2,1H3,(H,13,14) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable Rat (as animal) Sprague-Dawley 40 Male/Female oral: gavage 6.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: The United Kingdom Carboxin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin 18Oct2010 2010 doi:10.2903/j.efsa.2010.1857
+Carboxin 226-031-1 5234-68-4 single chemical entity Component is identical to the substance Carboxin 226-031-1 5234-68-4 2-methyl-N-phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide Carboxin C12H13NO2S CC1=C(SCCO1)C(=O)Nc2ccccc2 InChI=1/C12H13NO2S/c1-9-11(16-8-7-15-9)12(14)13-10-5-3-2-4-6-10/h2-6H,7-8H2,1H3,(H,13,14) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable Rat (as animal) Sprague-Dawley 40 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: The United Kingdom Carboxin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin 18Oct2010 2010 doi:10.2903/j.efsa.2010.1857
+Carboxin 226-031-1 5234-68-4 single chemical entity Component is identical to the substance Carboxin 226-031-1 5234-68-4 2-methyl-N-phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide Carboxin C12H13NO2S CC1=C(SCCO1)C(=O)Nc2ccccc2 InChI=1/C12H13NO2S/c1-9-11(16-8-7-15-9)12(14)13-10-5-3-2-4-6-10/h2-6H,7-8H2,1H3,(H,13,14) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable Rat (as animal) Sprague-Dawley 10 Male/Female oral: gavage 6.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: The United Kingdom Carboxin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin 18Oct2010 2010 doi:10.2903/j.efsa.2010.1857
+Carboxin 226-031-1 5234-68-4 single chemical entity Component is a metabolite of the substance 2-methyl-5,6-dihydro-1,4-oxathiine-3-carboxamide 4-oxide 2-methyl-5,6-dihydro-1,4-oxathiine-3-carboxamide 4-oxide Carboxin metabolite (P/V-54) C6H9NO3S CC=1OCCS(=O)C=1C(N)=O InChI=1/C6H9NO3S/c1-4-5(6(7)8)11(9)3-2-10-4/h2-3H2,1H3,(H2,7,8) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Carboxin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin 18Oct2010 2010 doi:10.2903/j.efsa.2010.1857
+Carboxin 226-031-1 5234-68-4 single chemical entity Component is a metabolite of the substance 2-methyl-5,6-dihydro-1,4-oxathiine-3-carboxamide 4-oxide 2-methyl-5,6-dihydro-1,4-oxathiine-3-carboxamide 4-oxide Carboxin metabolite (P/V-54) C6H9NO3S CC=1OCCS(=O)C=1C(N)=O InChI=1/C6H9NO3S/c1-4-5(6(7)8)11(9)3-2-10-4/h2-3H2,1H3,(H2,7,8) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Carboxin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin 18Oct2010 2010 doi:10.2903/j.efsa.2010.1857
+Carboxin 226-031-1 5234-68-4 single chemical entity Component is a metabolite of the substance 2-methyl-5,6-dihydro-1,4-oxathiine-3-carboxamide 4-oxide 2-methyl-5,6-dihydro-1,4-oxathiine-3-carboxamide 4-oxide Carboxin metabolite (P/V-54) C6H9NO3S CC=1OCCS(=O)C=1C(N)=O InChI=1/C6H9NO3S/c1-4-5(6(7)8)11(9)3-2-10-4/h2-3H2,1H3,(H2,7,8) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Carboxin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin 18Oct2010 2010 doi:10.2903/j.efsa.2010.1857
+Carboxin 226-031-1 5234-68-4 single chemical entity Component is a metabolite of the substance 2-methyl-5,6-dihydro-1,4-oxathiine-3-carboxamide 4-oxide 2-methyl-5,6-dihydro-1,4-oxathiine-3-carboxamide 4-oxide Carboxin metabolite (P/V-54) C6H9NO3S CC=1OCCS(=O)C=1C(N)=O InChI=1/C6H9NO3S/c1-4-5(6(7)8)11(9)3-2-10-4/h2-3H2,1H3,(H2,7,8) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Carboxin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin 18Oct2010 2010 doi:10.2903/j.efsa.2010.1857
+Carboxin 226-031-1 5234-68-4 single chemical entity Component is a metabolite of the substance 2-methyl-5,6-dihydro-1,4-oxathiine-3-carboxamide 4-oxide 2-methyl-5,6-dihydro-1,4-oxathiine-3-carboxamide 4-oxide Carboxin metabolite (P/V-54) C6H9NO3S CC=1OCCS(=O)C=1C(N)=O InChI=1/C6H9NO3S/c1-4-5(6(7)8)11(9)3-2-10-4/h2-3H2,1H3,(H2,7,8) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Carboxin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin 18Oct2010 2010 doi:10.2903/j.efsa.2010.1857
+Carboxin 226-031-1 5234-68-4 single chemical entity Component is a metabolite of the substance 2-methyl-5,6-dihydro-1,4-oxathiine-3-carboxamide 4-oxide 2-methyl-5,6-dihydro-1,4-oxathiine-3-carboxamide 4-oxide Carboxin metabolite (P/V-54) C6H9NO3S CC=1OCCS(=O)C=1C(N)=O InChI=1/C6H9NO3S/c1-4-5(6(7)8)11(9)3-2-10-4/h2-3H2,1H3,(H2,7,8) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Carboxin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin 18Oct2010 2010 doi:10.2903/j.efsa.2010.1857
+Carboxin 226-031-1 5234-68-4 single chemical entity Component is a metabolite of the substance 2-methyl-5,6-dihydro-1,4-oxathiine-3-carboxamide 4-oxide 2-methyl-5,6-dihydro-1,4-oxathiine-3-carboxamide 4-oxide Carboxin metabolite (P/V-54) C6H9NO3S CC=1OCCS(=O)C=1C(N)=O InChI=1/C6H9NO3S/c1-4-5(6(7)8)11(9)3-2-10-4/h2-3H2,1H3,(H2,7,8) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Carboxin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin 18Oct2010 2010 doi:10.2903/j.efsa.2010.1857
+Carboxin 226-031-1 5234-68-4 single chemical entity Component is a metabolite of the substance 2-methyl-5,6-dihydro-1,4-oxathiine-3-carboxamide 4-oxide 2-methyl-5,6-dihydro-1,4-oxathiine-3-carboxamide 4-oxide Carboxin metabolite (P/V-54) C6H9NO3S CC=1OCCS(=O)C=1C(N)=O InChI=1/C6H9NO3S/c1-4-5(6(7)8)11(9)3-2-10-4/h2-3H2,1H3,(H2,7,8) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Carboxin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin 18Oct2010 2010 doi:10.2903/j.efsa.2010.1857
+Carboxin 226-031-1 5234-68-4 single chemical entity Component is a metabolite of the substance 2-methyl-5,6-dihydro-1,4-oxathiine-3-carboxamide 4-oxide 2-methyl-5,6-dihydro-1,4-oxathiine-3-carboxamide 4-oxide Carboxin metabolite (P/V-54) C6H9NO3S CC=1OCCS(=O)C=1C(N)=O InChI=1/C6H9NO3S/c1-4-5(6(7)8)11(9)3-2-10-4/h2-3H2,1H3,(H2,7,8) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Carboxin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin 18Oct2010 2010 doi:10.2903/j.efsa.2010.1857
+Carboxin 226-031-1 5234-68-4 single chemical entity Component is a metabolite of the substance 2-methyl-5,6-dihydro-1,4-oxathiine-3-carboxamide 4-oxide 2-methyl-5,6-dihydro-1,4-oxathiine-3-carboxamide 4-oxide Carboxin metabolite (P/V-54) C6H9NO3S CC=1OCCS(=O)C=1C(N)=O InChI=1/C6H9NO3S/c1-4-5(6(7)8)11(9)3-2-10-4/h2-3H2,1H3,(H2,7,8) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Carboxin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin 18Oct2010 2010 doi:10.2903/j.efsa.2010.1857
+Carboxin 226-031-1 5234-68-4 single chemical entity Component is a metabolite of the substance 2-methyl-5,6-dihydro-1,4-oxathiine-3-carboxamide 4-oxide 2-methyl-5,6-dihydro-1,4-oxathiine-3-carboxamide 4-oxide Carboxin metabolite (P/V-54) C6H9NO3S CC=1OCCS(=O)C=1C(N)=O InChI=1/C6H9NO3S/c1-4-5(6(7)8)11(9)3-2-10-4/h2-3H2,1H3,(H2,7,8) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: The United Kingdom Carboxin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin 18Oct2010 2010 doi:10.2903/j.efsa.2010.1857
+Carboxin 226-031-1 5234-68-4 single chemical entity Component is a metabolite of the substance 2-methyl-5,6-dihydro-1,4-oxathiine-3-carboxamide 4-oxide 2-methyl-5,6-dihydro-1,4-oxathiine-3-carboxamide 4-oxide Carboxin metabolite (P/V-54) C6H9NO3S CC=1OCCS(=O)C=1C(N)=O InChI=1/C6H9NO3S/c1-4-5(6(7)8)11(9)3-2-10-4/h2-3H2,1H3,(H2,7,8) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: The United Kingdom Carboxin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin 18Oct2010 2010 doi:10.2903/j.efsa.2010.1857
+Carboxin 226-031-1 5234-68-4 single chemical entity Component is a metabolite of the substance 2-methyl-5,6-dihydro-1,4-oxathiine-3-carboxamide 4-oxide 2-methyl-5,6-dihydro-1,4-oxathiine-3-carboxamide 4-oxide Carboxin metabolite (P/V-54) C6H9NO3S CC=1OCCS(=O)C=1C(N)=O InChI=1/C6H9NO3S/c1-4-5(6(7)8)11(9)3-2-10-4/h2-3H2,1H3,(H2,7,8) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Carboxin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin 18Oct2010 2010 doi:10.2903/j.efsa.2010.1857
+Carboxin 226-031-1 5234-68-4 single chemical entity Component is a metabolite of the substance 2-methyl-5,6-dihydro-1,4-oxathiine-3-carboxamide 4-oxide 2-methyl-5,6-dihydro-1,4-oxathiine-3-carboxamide 4-oxide Carboxin metabolite (P/V-54) C6H9NO3S CC=1OCCS(=O)C=1C(N)=O InChI=1/C6H9NO3S/c1-4-5(6(7)8)11(9)3-2-10-4/h2-3H2,1H3,(H2,7,8) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Carboxin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin 18Oct2010 2010 doi:10.2903/j.efsa.2010.1857
+Carboxin 226-031-1 5234-68-4 single chemical entity Component is identical to the substance Carboxin 226-031-1 5234-68-4 2-methyl-N-phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide Carboxin C12H13NO2S CC1=C(SCCO1)C(=O)Nc2ccccc2 InChI=1/C12H13NO2S/c1-9-11(16-8-7-15-9)12(14)13-10-5-3-2-4-6-10/h2-6H,7-8H2,1H3,(H,13,14) organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Sprague-Dawley 3 Male oral: gavage 4.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Carboxin (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin 18Oct2010 2010 doi:10.2903/j.efsa.2010.1857
+Carboxin 226-031-1 5234-68-4 single chemical entity Component is identical to the substance Carboxin 226-031-1 5234-68-4 2-methyl-N-phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide Carboxin C12H13NO2S CC1=C(SCCO1)C(=O)Nc2ccccc2 InChI=1/C12H13NO2S/c1-9-11(16-8-7-15-9)12(14)13-10-5-3-2-4-6-10/h2-6H,7-8H2,1H3,(H,13,14) organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Sprague-Dawley 3 Male oral: gavage 16.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Carboxin (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin 18Oct2010 2010 doi:10.2903/j.efsa.2010.1857
+Dichlorprop-P 15165-67-0 single chemical entity Component is identical to the substance Dichlorprop-P 15165-67-0 (2R)-2-(2,4-dichlorophenoxy)propanoic acid Dichlorprop-p C9H8Cl2O3 Clc1cc(Cl)ccc1O[C@H](C)C(=O)O InChI=1S/C9H8Cl2O3/c1-5(9(12)13)14-8-3-2-6(10)4-7(8)11/h2-5H,1H3,(H,12,13)/t5-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Denmark Dichlorprop-p 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dichlorprop-P 13Nov2012 2012 doi:10.2903/j.efsa.2012.2950
+Dichlorprop-P 15165-67-0 single chemical entity Component is identical to the substance Dichlorprop-P 15165-67-0 (2R)-2-(2,4-dichlorophenoxy)propanoic acid Dichlorprop-p C9H8Cl2O3 Clc1cc(Cl)ccc1O[C@H](C)C(=O)O InChI=1S/C9H8Cl2O3/c1-5(9(12)13)14-8-3-2-6(10)4-7(8)11/h2-5H,1H3,(H,12,13)/t5-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Denmark Dichlorprop-p 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dichlorprop-P 13Nov2012 2012 doi:10.2903/j.efsa.2012.2950
+Dichlorprop-P 15165-67-0 single chemical entity Component is identical to the substance Dichlorprop-P 15165-67-0 (2R)-2-(2,4-dichlorophenoxy)propanoic acid Dichlorprop-p C9H8Cl2O3 Clc1cc(Cl)ccc1O[C@H](C)C(=O)O InChI=1S/C9H8Cl2O3/c1-5(9(12)13)14-8-3-2-6(10)4-7(8)11/h2-5H,1H3,(H,12,13)/t5-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Denmark Dichlorprop-p 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dichlorprop-P 13Nov2012 2012 doi:10.2903/j.efsa.2012.2950
+Dichlorprop-P 15165-67-0 single chemical entity Component is identical to the substance Dichlorprop-P 15165-67-0 (2R)-2-(2,4-dichlorophenoxy)propanoic acid Dichlorprop-p C9H8Cl2O3 Clc1cc(Cl)ccc1O[C@H](C)C(=O)O InChI=1S/C9H8Cl2O3/c1-5(9(12)13)14-8-3-2-6(10)4-7(8)11/h2-5H,1H3,(H,12,13)/t5-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Denmark Dichlorprop-p 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dichlorprop-P 13Nov2012 2012 doi:10.2903/j.efsa.2012.2950
+Dichlorprop-P 15165-67-0 single chemical entity Component is identical to the substance Dichlorprop-P 15165-67-0 (2R)-2-(2,4-dichlorophenoxy)propanoic acid Dichlorprop-p C9H8Cl2O3 Clc1cc(Cl)ccc1O[C@H](C)C(=O)O InChI=1S/C9H8Cl2O3/c1-5(9(12)13)14-8-3-2-6(10)4-7(8)11/h2-5H,1H3,(H,12,13)/t5-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Denmark Dichlorprop-p 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dichlorprop-P 13Nov2012 2012 doi:10.2903/j.efsa.2012.2950
+Dichlorprop-P 15165-67-0 single chemical entity Component is identical to the substance Dichlorprop-P 15165-67-0 (2R)-2-(2,4-dichlorophenoxy)propanoic acid Dichlorprop-p C9H8Cl2O3 Clc1cc(Cl)ccc1O[C@H](C)C(=O)O InChI=1S/C9H8Cl2O3/c1-5(9(12)13)14-8-3-2-6(10)4-7(8)11/h2-5H,1H3,(H,12,13)/t5-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Denmark Dichlorprop-p 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dichlorprop-P 13Nov2012 2012 doi:10.2903/j.efsa.2012.2950
+Dichlorprop-P 15165-67-0 single chemical entity Component is identical to the substance Dichlorprop-P 15165-67-0 (2R)-2-(2,4-dichlorophenoxy)propanoic acid Dichlorprop-p C9H8Cl2O3 Clc1cc(Cl)ccc1O[C@H](C)C(=O)O InChI=1S/C9H8Cl2O3/c1-5(9(12)13)14-8-3-2-6(10)4-7(8)11/h2-5H,1H3,(H,12,13)/t5-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Denmark Dichlorprop-p 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dichlorprop-P 13Nov2012 2012 doi:10.2903/j.efsa.2012.2950
+Dichlorprop-P 15165-67-0 single chemical entity Component is identical to the substance Dichlorprop-P 15165-67-0 (2R)-2-(2,4-dichlorophenoxy)propanoic acid Dichlorprop-p C9H8Cl2O3 Clc1cc(Cl)ccc1O[C@H](C)C(=O)O InChI=1S/C9H8Cl2O3/c1-5(9(12)13)14-8-3-2-6(10)4-7(8)11/h2-5H,1H3,(H,12,13)/t5-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Denmark Dichlorprop-p 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dichlorprop-P 13Nov2012 2012 doi:10.2903/j.efsa.2012.2950
+Dichlorprop-P 15165-67-0 single chemical entity Component is identical to the substance Dichlorprop-P 15165-67-0 (2R)-2-(2,4-dichlorophenoxy)propanoic acid Dichlorprop-p C9H8Cl2O3 Clc1cc(Cl)ccc1O[C@H](C)C(=O)O InChI=1S/C9H8Cl2O3/c1-5(9(12)13)14-8-3-2-6(10)4-7(8)11/h2-5H,1H3,(H,12,13)/t5-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Denmark Dichlorprop-p 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dichlorprop-P 13Nov2012 2012 doi:10.2903/j.efsa.2012.2950
+Dichlorprop-P 15165-67-0 single chemical entity Component is identical to the substance Dichlorprop-P 15165-67-0 (2R)-2-(2,4-dichlorophenoxy)propanoic acid Dichlorprop-p C9H8Cl2O3 Clc1cc(Cl)ccc1O[C@H](C)C(=O)O InChI=1S/C9H8Cl2O3/c1-5(9(12)13)14-8-3-2-6(10)4-7(8)11/h2-5H,1H3,(H,12,13)/t5-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Denmark Dichlorprop-p 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dichlorprop-P 13Nov2012 2012 doi:10.2903/j.efsa.2012.2950
+Dichlorprop-P 15165-67-0 single chemical entity Component is identical to the substance Dichlorprop-P 15165-67-0 (2R)-2-(2,4-dichlorophenoxy)propanoic acid Dichlorprop-p C9H8Cl2O3 Clc1cc(Cl)ccc1O[C@H](C)C(=O)O InChI=1S/C9H8Cl2O3/c1-5(9(12)13)14-8-3-2-6(10)4-7(8)11/h2-5H,1H3,(H,12,13)/t5-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Denmark Dichlorprop-p 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dichlorprop-P 13Nov2012 2012 doi:10.2903/j.efsa.2012.2950
+Dichlorprop-P 15165-67-0 single chemical entity Component is identical to the substance Dichlorprop-P 15165-67-0 (2R)-2-(2,4-dichlorophenoxy)propanoic acid Dichlorprop-p C9H8Cl2O3 Clc1cc(Cl)ccc1O[C@H](C)C(=O)O InChI=1S/C9H8Cl2O3/c1-5(9(12)13)14-8-3-2-6(10)4-7(8)11/h2-5H,1H3,(H,12,13)/t5-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Denmark Dichlorprop-p 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dichlorprop-P 13Nov2012 2012 doi:10.2903/j.efsa.2012.2950
+Dichlorprop-P 15165-67-0 single chemical entity Component is identical to the substance Dichlorprop-P 15165-67-0 (2R)-2-(2,4-dichlorophenoxy)propanoic acid Dichlorprop-p C9H8Cl2O3 Clc1cc(Cl)ccc1O[C@H](C)C(=O)O InChI=1S/C9H8Cl2O3/c1-5(9(12)13)14-8-3-2-6(10)4-7(8)11/h2-5H,1H3,(H,12,13)/t5-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Denmark Dichlorprop-p 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dichlorprop-P 13Nov2012 2012 doi:10.2903/j.efsa.2012.2950
+Dichlorprop-P 15165-67-0 single chemical entity Component is identical to the substance Dichlorprop-P 15165-67-0 (2R)-2-(2,4-dichlorophenoxy)propanoic acid Dichlorprop-p C9H8Cl2O3 Clc1cc(Cl)ccc1O[C@H](C)C(=O)O InChI=1S/C9H8Cl2O3/c1-5(9(12)13)14-8-3-2-6(10)4-7(8)11/h2-5H,1H3,(H,12,13)/t5-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Denmark Dichlorprop-p 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dichlorprop-P 13Nov2012 2012 doi:10.2903/j.efsa.2012.2950
+Dichlorprop-P 15165-67-0 single chemical entity Component is identical to the substance Dichlorprop-P 15165-67-0 (2R)-2-(2,4-dichlorophenoxy)propanoic acid Dichlorprop-p C9H8Cl2O3 Clc1cc(Cl)ccc1O[C@H](C)C(=O)O InChI=1S/C9H8Cl2O3/c1-5(9(12)13)14-8-3-2-6(10)4-7(8)11/h2-5H,1H3,(H,12,13)/t5-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Denmark Dichlorprop-p 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dichlorprop-P 13Nov2012 2012 doi:10.2903/j.efsa.2012.2950
+Dichlorprop-P 15165-67-0 single chemical entity Component is identical to the substance Dichlorprop-P 15165-67-0 (2R)-2-(2,4-dichlorophenoxy)propanoic acid Dichlorprop-p C9H8Cl2O3 Clc1cc(Cl)ccc1O[C@H](C)C(=O)O InChI=1S/C9H8Cl2O3/c1-5(9(12)13)14-8-3-2-6(10)4-7(8)11/h2-5H,1H3,(H,12,13)/t5-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Denmark Dichlorprop-p 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dichlorprop-P 13Nov2012 2012 doi:10.2903/j.efsa.2012.2950
+Dichlorprop-P 15165-67-0 single chemical entity Component is identical to the substance Dichlorprop-P 15165-67-0 (2R)-2-(2,4-dichlorophenoxy)propanoic acid Dichlorprop-p C9H8Cl2O3 Clc1cc(Cl)ccc1O[C@H](C)C(=O)O InChI=1S/C9H8Cl2O3/c1-5(9(12)13)14-8-3-2-6(10)4-7(8)11/h2-5H,1H3,(H,12,13)/t5-/m1/s1 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Denmark Dichlorprop-p 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dichlorprop-P 13Nov2012 2012 doi:10.2903/j.efsa.2012.2950
+Dichlorprop-P 15165-67-0 single chemical entity Component is identical to the substance Dichlorprop-P 15165-67-0 (2R)-2-(2,4-dichlorophenoxy)propanoic acid Dichlorprop-p C9H8Cl2O3 Clc1cc(Cl)ccc1O[C@H](C)C(=O)O InChI=1S/C9H8Cl2O3/c1-5(9(12)13)14-8-3-2-6(10)4-7(8)11/h2-5H,1H3,(H,12,13)/t5-/m1/s1 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Denmark Dichlorprop-p 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dichlorprop-P 13Nov2012 2012 doi:10.2903/j.efsa.2012.2950
+Dichlorprop-P 15165-67-0 single chemical entity Component is identical to the substance Dichlorprop-P 15165-67-0 (2R)-2-(2,4-dichlorophenoxy)propanoic acid Dichlorprop-p C9H8Cl2O3 Clc1cc(Cl)ccc1O[C@H](C)C(=O)O InChI=1S/C9H8Cl2O3/c1-5(9(12)13)14-8-3-2-6(10)4-7(8)11/h2-5H,1H3,(H,12,13)/t5-/m1/s1 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: Denmark Dichlorprop-p 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dichlorprop-P 13Nov2012 2012 doi:10.2903/j.efsa.2012.2950
+Dichlorprop-P 15165-67-0 single chemical entity Component is identical to the substance Dichlorprop-P 15165-67-0 (2R)-2-(2,4-dichlorophenoxy)propanoic acid Dichlorprop-p C9H8Cl2O3 Clc1cc(Cl)ccc1O[C@H](C)C(=O)O InChI=1S/C9H8Cl2O3/c1-5(9(12)13)14-8-3-2-6(10)4-7(8)11/h2-5H,1H3,(H,12,13)/t5-/m1/s1 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: Denmark Dichlorprop-p 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dichlorprop-P 13Nov2012 2012 doi:10.2903/j.efsa.2012.2950
+Dichlorprop-P 15165-67-0 single chemical entity Component is identical to the substance Dichlorprop-P 15165-67-0 (2R)-2-(2,4-dichlorophenoxy)propanoic acid Dichlorprop-p C9H8Cl2O3 Clc1cc(Cl)ccc1O[C@H](C)C(=O)O InChI=1S/C9H8Cl2O3/c1-5(9(12)13)14-8-3-2-6(10)4-7(8)11/h2-5H,1H3,(H,12,13)/t5-/m1/s1 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Denmark Dichlorprop-p 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dichlorprop-P 13Nov2012 2012 doi:10.2903/j.efsa.2012.2950
+Dichlorprop-P 15165-67-0 single chemical entity Component is identical to the substance Dichlorprop-P 15165-67-0 (2R)-2-(2,4-dichlorophenoxy)propanoic acid Dichlorprop-p C9H8Cl2O3 Clc1cc(Cl)ccc1O[C@H](C)C(=O)O InChI=1S/C9H8Cl2O3/c1-5(9(12)13)14-8-3-2-6(10)4-7(8)11/h2-5H,1H3,(H,12,13)/t5-/m1/s1 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Denmark Dichlorprop-p 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dichlorprop-P 13Nov2012 2012 doi:10.2903/j.efsa.2012.2950
+Dichlorprop-P 15165-67-0 single chemical entity Component is identical to the substance Dichlorprop-P 15165-67-0 (2R)-2-(2,4-dichlorophenoxy)propanoic acid Dichlorprop-p C9H8Cl2O3 Clc1cc(Cl)ccc1O[C@H](C)C(=O)O InChI=1S/C9H8Cl2O3/c1-5(9(12)13)14-8-3-2-6(10)4-7(8)11/h2-5H,1H3,(H,12,13)/t5-/m1/s1 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Positive RMS: Denmark Dichlorprop-p 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dichlorprop-P 13Nov2012 2012 doi:10.2903/j.efsa.2012.2950
+Dichlorprop-P 15165-67-0 single chemical entity Component is identical to the substance Dichlorprop-P 15165-67-0 (2R)-2-(2,4-dichlorophenoxy)propanoic acid Dichlorprop-p C9H8Cl2O3 Clc1cc(Cl)ccc1O[C@H](C)C(=O)O InChI=1S/C9H8Cl2O3/c1-5(9(12)13)14-8-3-2-6(10)4-7(8)11/h2-5H,1H3,(H,12,13)/t5-/m1/s1 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Denmark Dichlorprop-p 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dichlorprop-P 13Nov2012 2012 doi:10.2903/j.efsa.2012.2950
+Dichlorprop-P 15165-67-0 single chemical entity Component is identical to the substance Dichlorprop-P 15165-67-0 (2R)-2-(2,4-dichlorophenoxy)propanoic acid Dichlorprop-p C9H8Cl2O3 Clc1cc(Cl)ccc1O[C@H](C)C(=O)O InChI=1S/C9H8Cl2O3/c1-5(9(12)13)14-8-3-2-6(10)4-7(8)11/h2-5H,1H3,(H,12,13)/t5-/m1/s1 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 24 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Denmark Dichlorprop-p 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dichlorprop-P 13Nov2012 2012 doi:10.2903/j.efsa.2012.2950
+Dichlorprop-P 15165-67-0 single chemical entity Component is identical to the substance Dichlorprop-P 15165-67-0 (2R)-2-(2,4-dichlorophenoxy)propanoic acid Dichlorprop-p C9H8Cl2O3 Clc1cc(Cl)ccc1O[C@H](C)C(=O)O InChI=1S/C9H8Cl2O3/c1-5(9(12)13)14-8-3-2-6(10)4-7(8)11/h2-5H,1H3,(H,12,13)/t5-/m1/s1 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 24 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Denmark Dichlorprop-p 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dichlorprop-P 13Nov2012 2012 doi:10.2903/j.efsa.2012.2950
+Dichlorprop-P 15165-67-0 single chemical entity Component is identical to the substance Dichlorprop-P 15165-67-0 (2R)-2-(2,4-dichlorophenoxy)propanoic acid Dichlorprop-p C9H8Cl2O3 Clc1cc(Cl)ccc1O[C@H](C)C(=O)O InChI=1S/C9H8Cl2O3/c1-5(9(12)13)14-8-3-2-6(10)4-7(8)11/h2-5H,1H3,(H,12,13)/t5-/m1/s1 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 24 Male/Female oral: gavage 72.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Denmark Dichlorprop-p 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dichlorprop-P 13Nov2012 2012 doi:10.2903/j.efsa.2012.2950
+Dichlorprop-P 15165-67-0 single chemical entity Component is identical to the substance Dichlorprop-P 15165-67-0 (2R)-2-(2,4-dichlorophenoxy)propanoic acid Dichlorprop-p C9H8Cl2O3 Clc1cc(Cl)ccc1O[C@H](C)C(=O)O InChI=1S/C9H8Cl2O3/c1-5(9(12)13)14-8-3-2-6(10)4-7(8)11/h2-5H,1H3,(H,12,13)/t5-/m1/s1 organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Wistar 5 Male oral: gavage 16.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Denmark Dichlorprop-p 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dichlorprop-P 13Nov2012 2012 doi:10.2903/j.efsa.2012.2950
+Dichlorprop-P 15165-67-0 single chemical entity Component is identical to the substance Dichlorprop-P 15165-67-0 (2R)-2-(2,4-dichlorophenoxy)propanoic acid Dichlorprop-p C9H8Cl2O3 Clc1cc(Cl)ccc1O[C@H](C)C(=O)O InChI=1S/C9H8Cl2O3/c1-5(9(12)13)14-8-3-2-6(10)4-7(8)11/h2-5H,1H3,(H,12,13)/t5-/m1/s1 organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Wistar 5 Male oral: gavage 2.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Denmark Dichlorprop-p 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dichlorprop-P 13Nov2012 2012 doi:10.2903/j.efsa.2012.2950
+Diflufenican 83164-33-4 single chemical entity Component is identical to the substance Diflufenican 83164-33-4 N-(2,4-difluorophenyl)-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxamide Diflufenican C19H11F5N2O2 C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)NC3=C(C=C(C=C3)F)F)C(F)(F)F InChI=1S/C19H11F5N2O2/c20-12-6-7-16(15(21)10-12)26-17(27)14-5-2-8-25-18(14)28-13-4-1-3-11(9-13)19(22,23)24/h1-10H,(H,26,27) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Diflufenican 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican 14Feb2008 2008 doi:10.2903/j.efsa.2008.122r
+Diflufenican 83164-33-4 single chemical entity Component is identical to the substance Diflufenican 83164-33-4 N-(2,4-difluorophenyl)-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxamide Diflufenican C19H11F5N2O2 C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)NC3=C(C=C(C=C3)F)F)C(F)(F)F InChI=1S/C19H11F5N2O2/c20-12-6-7-16(15(21)10-12)26-17(27)14-5-2-8-25-18(14)28-13-4-1-3-11(9-13)19(22,23)24/h1-10H,(H,26,27) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Diflufenican 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican 14Feb2008 2008 doi:10.2903/j.efsa.2008.122r
+Diflufenican 83164-33-4 single chemical entity Component is identical to the substance Diflufenican 83164-33-4 N-(2,4-difluorophenyl)-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxamide Diflufenican C19H11F5N2O2 C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)NC3=C(C=C(C=C3)F)F)C(F)(F)F InChI=1S/C19H11F5N2O2/c20-12-6-7-16(15(21)10-12)26-17(27)14-5-2-8-25-18(14)28-13-4-1-3-11(9-13)19(22,23)24/h1-10H,(H,26,27) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Diflufenican 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican 14Feb2008 2008 doi:10.2903/j.efsa.2008.122r
+Diflufenican 83164-33-4 single chemical entity Component is identical to the substance Diflufenican 83164-33-4 N-(2,4-difluorophenyl)-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxamide Diflufenican C19H11F5N2O2 C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)NC3=C(C=C(C=C3)F)F)C(F)(F)F InChI=1S/C19H11F5N2O2/c20-12-6-7-16(15(21)10-12)26-17(27)14-5-2-8-25-18(14)28-13-4-1-3-11(9-13)19(22,23)24/h1-10H,(H,26,27) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Diflufenican 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican 14Feb2008 2008 doi:10.2903/j.efsa.2008.122r
+Diflufenican 83164-33-4 single chemical entity Component is identical to the substance Diflufenican 83164-33-4 N-(2,4-difluorophenyl)-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxamide Diflufenican C19H11F5N2O2 C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)NC3=C(C=C(C=C3)F)F)C(F)(F)F InChI=1S/C19H11F5N2O2/c20-12-6-7-16(15(21)10-12)26-17(27)14-5-2-8-25-18(14)28-13-4-1-3-11(9-13)19(22,23)24/h1-10H,(H,26,27) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Diflufenican 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican 14Feb2008 2008 doi:10.2903/j.efsa.2008.122r
+Diflufenican 83164-33-4 single chemical entity Component is identical to the substance Diflufenican 83164-33-4 N-(2,4-difluorophenyl)-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxamide Diflufenican C19H11F5N2O2 C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)NC3=C(C=C(C=C3)F)F)C(F)(F)F InChI=1S/C19H11F5N2O2/c20-12-6-7-16(15(21)10-12)26-17(27)14-5-2-8-25-18(14)28-13-4-1-3-11(9-13)19(22,23)24/h1-10H,(H,26,27) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Diflufenican 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican 14Feb2008 2008 doi:10.2903/j.efsa.2008.122r
+Diflufenican 83164-33-4 single chemical entity Component is identical to the substance Diflufenican 83164-33-4 N-(2,4-difluorophenyl)-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxamide Diflufenican C19H11F5N2O2 C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)NC3=C(C=C(C=C3)F)F)C(F)(F)F InChI=1S/C19H11F5N2O2/c20-12-6-7-16(15(21)10-12)26-17(27)14-5-2-8-25-18(14)28-13-4-1-3-11(9-13)19(22,23)24/h1-10H,(H,26,27) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Diflufenican 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican 14Feb2008 2008 doi:10.2903/j.efsa.2008.122r
+Diflufenican 83164-33-4 single chemical entity Component is identical to the substance Diflufenican 83164-33-4 N-(2,4-difluorophenyl)-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxamide Diflufenican C19H11F5N2O2 C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)NC3=C(C=C(C=C3)F)F)C(F)(F)F InChI=1S/C19H11F5N2O2/c20-12-6-7-16(15(21)10-12)26-17(27)14-5-2-8-25-18(14)28-13-4-1-3-11(9-13)19(22,23)24/h1-10H,(H,26,27) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Diflufenican 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican 14Feb2008 2008 doi:10.2903/j.efsa.2008.122r
+Diflufenican 83164-33-4 single chemical entity Component is identical to the substance Diflufenican 83164-33-4 N-(2,4-difluorophenyl)-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxamide Diflufenican C19H11F5N2O2 C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)NC3=C(C=C(C=C3)F)F)C(F)(F)F InChI=1S/C19H11F5N2O2/c20-12-6-7-16(15(21)10-12)26-17(27)14-5-2-8-25-18(14)28-13-4-1-3-11(9-13)19(22,23)24/h1-10H,(H,26,27) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Diflufenican 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican 14Feb2008 2008 doi:10.2903/j.efsa.2008.122r
+Diflufenican 83164-33-4 single chemical entity Component is identical to the substance Diflufenican 83164-33-4 N-(2,4-difluorophenyl)-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxamide Diflufenican C19H11F5N2O2 C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)NC3=C(C=C(C=C3)F)F)C(F)(F)F InChI=1S/C19H11F5N2O2/c20-12-6-7-16(15(21)10-12)26-17(27)14-5-2-8-25-18(14)28-13-4-1-3-11(9-13)19(22,23)24/h1-10H,(H,26,27) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Diflufenican 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican 14Feb2008 2008 doi:10.2903/j.efsa.2008.122r
+Diflufenican 83164-33-4 single chemical entity Component is identical to the substance Diflufenican 83164-33-4 N-(2,4-difluorophenyl)-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxamide Diflufenican C19H11F5N2O2 C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)NC3=C(C=C(C=C3)F)F)C(F)(F)F InChI=1S/C19H11F5N2O2/c20-12-6-7-16(15(21)10-12)26-17(27)14-5-2-8-25-18(14)28-13-4-1-3-11(9-13)19(22,23)24/h1-10H,(H,26,27) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes without Negative RMS: The United Kingdom Diflufenican 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican 14Feb2008 2008 doi:10.2903/j.efsa.2008.122r
+Diflufenican 83164-33-4 single chemical entity Component is identical to the substance Diflufenican 83164-33-4 N-(2,4-difluorophenyl)-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxamide Diflufenican C19H11F5N2O2 C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)NC3=C(C=C(C=C3)F)F)C(F)(F)F InChI=1S/C19H11F5N2O2/c20-12-6-7-16(15(21)10-12)26-17(27)14-5-2-8-25-18(14)28-13-4-1-3-11(9-13)19(22,23)24/h1-10H,(H,26,27) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes with Negative RMS: The United Kingdom Diflufenican 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican 14Feb2008 2008 doi:10.2903/j.efsa.2008.122r
+Diflufenican 83164-33-4 single chemical entity Component is identical to the substance Diflufenican 83164-33-4 N-(2,4-difluorophenyl)-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxamide Diflufenican C19H11F5N2O2 C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)NC3=C(C=C(C=C3)F)F)C(F)(F)F InChI=1S/C19H11F5N2O2/c20-12-6-7-16(15(21)10-12)26-17(27)14-5-2-8-25-18(14)28-13-4-1-3-11(9-13)19(22,23)24/h1-10H,(H,26,27) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Diflufenican 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican 14Feb2008 2008 doi:10.2903/j.efsa.2008.122r
+Diflufenican 83164-33-4 single chemical entity Component is identical to the substance Diflufenican 83164-33-4 N-(2,4-difluorophenyl)-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxamide Diflufenican C19H11F5N2O2 C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)NC3=C(C=C(C=C3)F)F)C(F)(F)F InChI=1S/C19H11F5N2O2/c20-12-6-7-16(15(21)10-12)26-17(27)14-5-2-8-25-18(14)28-13-4-1-3-11(9-13)19(22,23)24/h1-10H,(H,26,27) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Diflufenican 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican 14Feb2008 2008 doi:10.2903/j.efsa.2008.122r
+Diflufenican 83164-33-4 single chemical entity Component is identical to the substance Diflufenican 83164-33-4 N-(2,4-difluorophenyl)-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxamide Diflufenican C19H11F5N2O2 C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)NC3=C(C=C(C=C3)F)F)C(F)(F)F InChI=1S/C19H11F5N2O2/c20-12-6-7-16(15(21)10-12)26-17(27)14-5-2-8-25-18(14)28-13-4-1-3-11(9-13)19(22,23)24/h1-10H,(H,26,27) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: The United Kingdom Diflufenican 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican 14Feb2008 2008 doi:10.2903/j.efsa.2008.122r
+Diflufenican 83164-33-4 single chemical entity Component is identical to the substance Diflufenican 83164-33-4 N-(2,4-difluorophenyl)-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxamide Diflufenican C19H11F5N2O2 C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)NC3=C(C=C(C=C3)F)F)C(F)(F)F InChI=1S/C19H11F5N2O2/c20-12-6-7-16(15(21)10-12)26-17(27)14-5-2-8-25-18(14)28-13-4-1-3-11(9-13)19(22,23)24/h1-10H,(H,26,27) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Positive no information RMS: The United Kingdom Diflufenican 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican 14Feb2008 2008 doi:10.2903/j.efsa.2008.122r
+Diflufenican 83164-33-4 single chemical entity Component is identical to the substance Diflufenican 83164-33-4 N-(2,4-difluorophenyl)-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxamide Diflufenican C19H11F5N2O2 C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)NC3=C(C=C(C=C3)F)F)C(F)(F)F InChI=1S/C19H11F5N2O2/c20-12-6-7-16(15(21)10-12)26-17(27)14-5-2-8-25-18(14)28-13-4-1-3-11(9-13)19(22,23)24/h1-10H,(H,26,27) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Diflufenican 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican 14Feb2008 2008 doi:10.2903/j.efsa.2008.122r
+Diflufenican 83164-33-4 single chemical entity Component is identical to the substance Diflufenican 83164-33-4 N-(2,4-difluorophenyl)-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxamide Diflufenican C19H11F5N2O2 C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)NC3=C(C=C(C=C3)F)F)C(F)(F)F InChI=1S/C19H11F5N2O2/c20-12-6-7-16(15(21)10-12)26-17(27)14-5-2-8-25-18(14)28-13-4-1-3-11(9-13)19(22,23)24/h1-10H,(H,26,27) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable Rat (as animal) Sprague-Dawley 10 Male/Female intraperitoneal 24.0000000000 h yes not applicable Negative indirect evidence-systemic toxicity RMS: The United Kingdom Diflufenican 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican 14Feb2008 2008 doi:10.2903/j.efsa.2008.122r
+Diflufenican 83164-33-4 single chemical entity Component is identical to the substance Diflufenican 83164-33-4 N-(2,4-difluorophenyl)-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxamide Diflufenican C19H11F5N2O2 C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)NC3=C(C=C(C=C3)F)F)C(F)(F)F InChI=1S/C19H11F5N2O2/c20-12-6-7-16(15(21)10-12)26-17(27)14-5-2-8-25-18(14)28-13-4-1-3-11(9-13)19(22,23)24/h1-10H,(H,26,27) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable Rat (as animal) Sprague-Dawley 10 Male/Female intraperitoneal 6.0000000000 h yes not applicable Negative indirect evidence-systemic toxicity RMS: The United Kingdom Diflufenican 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican 14Feb2008 2008 doi:10.2903/j.efsa.2008.122r
+Diflufenican 83164-33-4 single chemical entity Component is identical to the substance Diflufenican 83164-33-4 N-(2,4-difluorophenyl)-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxamide Diflufenican C19H11F5N2O2 C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)NC3=C(C=C(C=C3)F)F)C(F)(F)F InChI=1S/C19H11F5N2O2/c20-12-6-7-16(15(21)10-12)26-17(27)14-5-2-8-25-18(14)28-13-4-1-3-11(9-13)19(22,23)24/h1-10H,(H,26,27) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable Rat (as animal) Sprague-Dawley 10 Male/Female intraperitoneal 48.0000000000 h yes not applicable Negative indirect evidence-systemic toxicity RMS: The United Kingdom Diflufenican 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican 14Feb2008 2008 doi:10.2903/j.efsa.2008.122r
+Diflufenican 83164-33-4 single chemical entity Component is a metabolite of the substance 2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxylic acid 609-284-6 36701-89-0 2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxylic acid Not in list C13H8F3NO3 C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)O)C(F)(F)F InChI=1S/C13H8F3NO3/c14-13(15,16)8-3-1-4-9(7-8)20-11-10(12(18)19)5-2-6-17-11/h1-7H,(H,18,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Diflufenican 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican 14Feb2008 2008 doi:10.2903/j.efsa.2008.122r
+Diflufenican 83164-33-4 single chemical entity Component is a metabolite of the substance 2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxylic acid 609-284-6 36701-89-0 2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxylic acid Not in list C13H8F3NO3 C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)O)C(F)(F)F InChI=1S/C13H8F3NO3/c14-13(15,16)8-3-1-4-9(7-8)20-11-10(12(18)19)5-2-6-17-11/h1-7H,(H,18,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Diflufenican 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican 14Feb2008 2008 doi:10.2903/j.efsa.2008.122r
+Diflufenican 83164-33-4 single chemical entity Component is a metabolite of the substance 2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxylic acid 609-284-6 36701-89-0 2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxylic acid Not in list C13H8F3NO3 C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)O)C(F)(F)F InChI=1S/C13H8F3NO3/c14-13(15,16)8-3-1-4-9(7-8)20-11-10(12(18)19)5-2-6-17-11/h1-7H,(H,18,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Diflufenican 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican 14Feb2008 2008 doi:10.2903/j.efsa.2008.122r
+Diflufenican 83164-33-4 single chemical entity Component is a metabolite of the substance 2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxylic acid 609-284-6 36701-89-0 2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxylic acid Not in list C13H8F3NO3 C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)O)C(F)(F)F InChI=1S/C13H8F3NO3/c14-13(15,16)8-3-1-4-9(7-8)20-11-10(12(18)19)5-2-6-17-11/h1-7H,(H,18,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Diflufenican 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican 14Feb2008 2008 doi:10.2903/j.efsa.2008.122r
+Diflufenican 83164-33-4 single chemical entity Component is a metabolite of the substance 2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxylic acid 609-284-6 36701-89-0 2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxylic acid Not in list C13H8F3NO3 C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)O)C(F)(F)F InChI=1S/C13H8F3NO3/c14-13(15,16)8-3-1-4-9(7-8)20-11-10(12(18)19)5-2-6-17-11/h1-7H,(H,18,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Diflufenican 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican 14Feb2008 2008 doi:10.2903/j.efsa.2008.122r
+Diflufenican 83164-33-4 single chemical entity Component is a metabolite of the substance 2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxylic acid 609-284-6 36701-89-0 2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxylic acid Not in list C13H8F3NO3 C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)O)C(F)(F)F InChI=1S/C13H8F3NO3/c14-13(15,16)8-3-1-4-9(7-8)20-11-10(12(18)19)5-2-6-17-11/h1-7H,(H,18,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Diflufenican 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican 14Feb2008 2008 doi:10.2903/j.efsa.2008.122r
+Diflufenican 83164-33-4 single chemical entity Component is a metabolite of the substance 2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxylic acid 609-284-6 36701-89-0 2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxylic acid Not in list C13H8F3NO3 C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)O)C(F)(F)F InChI=1S/C13H8F3NO3/c14-13(15,16)8-3-1-4-9(7-8)20-11-10(12(18)19)5-2-6-17-11/h1-7H,(H,18,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Diflufenican 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican 14Feb2008 2008 doi:10.2903/j.efsa.2008.122r
+Diflufenican 83164-33-4 single chemical entity Component is a metabolite of the substance 2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxylic acid 609-284-6 36701-89-0 2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxylic acid Not in list C13H8F3NO3 C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)O)C(F)(F)F InChI=1S/C13H8F3NO3/c14-13(15,16)8-3-1-4-9(7-8)20-11-10(12(18)19)5-2-6-17-11/h1-7H,(H,18,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Diflufenican 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican 14Feb2008 2008 doi:10.2903/j.efsa.2008.122r
+Diflufenican 83164-33-4 single chemical entity Component is a metabolite of the substance 2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxylic acid 609-284-6 36701-89-0 2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxylic acid Not in list C13H8F3NO3 C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)O)C(F)(F)F InChI=1S/C13H8F3NO3/c14-13(15,16)8-3-1-4-9(7-8)20-11-10(12(18)19)5-2-6-17-11/h1-7H,(H,18,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Diflufenican 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican 14Feb2008 2008 doi:10.2903/j.efsa.2008.122r
+Diflufenican 83164-33-4 single chemical entity Component is a metabolite of the substance 2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxylic acid 609-284-6 36701-89-0 2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxylic acid Not in list C13H8F3NO3 C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)O)C(F)(F)F InChI=1S/C13H8F3NO3/c14-13(15,16)8-3-1-4-9(7-8)20-11-10(12(18)19)5-2-6-17-11/h1-7H,(H,18,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Diflufenican 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican 14Feb2008 2008 doi:10.2903/j.efsa.2008.122r
+Diflufenican 83164-33-4 single chemical entity Component is a metabolite of the substance 2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxylic acid 609-284-6 36701-89-0 2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxylic acid Not in list C13H8F3NO3 C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)O)C(F)(F)F InChI=1S/C13H8F3NO3/c14-13(15,16)8-3-1-4-9(7-8)20-11-10(12(18)19)5-2-6-17-11/h1-7H,(H,18,19) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes without Ambiguous RMS: The United Kingdom Diflufenican 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican 14Feb2008 2008 doi:10.2903/j.efsa.2008.122r
+Diflufenican 83164-33-4 single chemical entity Component is a metabolite of the substance 2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxylic acid 609-284-6 36701-89-0 2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxylic acid Not in list C13H8F3NO3 C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)O)C(F)(F)F InChI=1S/C13H8F3NO3/c14-13(15,16)8-3-1-4-9(7-8)20-11-10(12(18)19)5-2-6-17-11/h1-7H,(H,18,19) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes with Ambiguous RMS: The United Kingdom Diflufenican 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican 14Feb2008 2008 doi:10.2903/j.efsa.2008.122r
+Cyromazine 66215-27-8 single chemical entity Component is identical to the substance Cyromazine 66215-27-8 N2-cyclopropyl-1,3,5-triazine-2,4,6-triamine Cyromazine C6H10N6 Nc2nc(N)nc(NC1CC1)n2 InChI=1S/C6H10N6/c7-4-10-5(8)12-6(11-4)9-3-1-2-3/h3H,1-2H2,(H5,7,8,9,10,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Greece Cyromazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyromazine 21Oct2008 2008 doi:10.2903/j.efsa.2008.168r
+Cyromazine 66215-27-8 single chemical entity Component is identical to the substance Cyromazine 66215-27-8 N2-cyclopropyl-1,3,5-triazine-2,4,6-triamine Cyromazine C6H10N6 Nc2nc(N)nc(NC1CC1)n2 InChI=1S/C6H10N6/c7-4-10-5(8)12-6(11-4)9-3-1-2-3/h3H,1-2H2,(H5,7,8,9,10,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Greece Cyromazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyromazine 21Oct2008 2008 doi:10.2903/j.efsa.2008.168r
+Cyromazine 66215-27-8 single chemical entity Component is identical to the substance Cyromazine 66215-27-8 N2-cyclopropyl-1,3,5-triazine-2,4,6-triamine Cyromazine C6H10N6 Nc2nc(N)nc(NC1CC1)n2 InChI=1S/C6H10N6/c7-4-10-5(8)12-6(11-4)9-3-1-2-3/h3H,1-2H2,(H5,7,8,9,10,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Greece Cyromazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyromazine 21Oct2008 2008 doi:10.2903/j.efsa.2008.168r
+Cyromazine 66215-27-8 single chemical entity Component is identical to the substance Cyromazine 66215-27-8 N2-cyclopropyl-1,3,5-triazine-2,4,6-triamine Cyromazine C6H10N6 Nc2nc(N)nc(NC1CC1)n2 InChI=1S/C6H10N6/c7-4-10-5(8)12-6(11-4)9-3-1-2-3/h3H,1-2H2,(H5,7,8,9,10,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Greece Cyromazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyromazine 21Oct2008 2008 doi:10.2903/j.efsa.2008.168r
+Cyromazine 66215-27-8 single chemical entity Component is identical to the substance Cyromazine 66215-27-8 N2-cyclopropyl-1,3,5-triazine-2,4,6-triamine Cyromazine C6H10N6 Nc2nc(N)nc(NC1CC1)n2 InChI=1S/C6H10N6/c7-4-10-5(8)12-6(11-4)9-3-1-2-3/h3H,1-2H2,(H5,7,8,9,10,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Greece Cyromazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyromazine 21Oct2008 2008 doi:10.2903/j.efsa.2008.168r
+Cyromazine 66215-27-8 single chemical entity Component is identical to the substance Cyromazine 66215-27-8 N2-cyclopropyl-1,3,5-triazine-2,4,6-triamine Cyromazine C6H10N6 Nc2nc(N)nc(NC1CC1)n2 InChI=1S/C6H10N6/c7-4-10-5(8)12-6(11-4)9-3-1-2-3/h3H,1-2H2,(H5,7,8,9,10,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Greece Cyromazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyromazine 21Oct2008 2008 doi:10.2903/j.efsa.2008.168r
+Cyromazine 66215-27-8 single chemical entity Component is identical to the substance Cyromazine 66215-27-8 N2-cyclopropyl-1,3,5-triazine-2,4,6-triamine Cyromazine C6H10N6 Nc2nc(N)nc(NC1CC1)n2 InChI=1S/C6H10N6/c7-4-10-5(8)12-6(11-4)9-3-1-2-3/h3H,1-2H2,(H5,7,8,9,10,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Greece Cyromazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyromazine 21Oct2008 2008 doi:10.2903/j.efsa.2008.168r
+Cyromazine 66215-27-8 single chemical entity Component is identical to the substance Cyromazine 66215-27-8 N2-cyclopropyl-1,3,5-triazine-2,4,6-triamine Cyromazine C6H10N6 Nc2nc(N)nc(NC1CC1)n2 InChI=1S/C6H10N6/c7-4-10-5(8)12-6(11-4)9-3-1-2-3/h3H,1-2H2,(H5,7,8,9,10,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Greece Cyromazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyromazine 21Oct2008 2008 doi:10.2903/j.efsa.2008.168r
+Cyromazine 66215-27-8 single chemical entity Component is identical to the substance Cyromazine 66215-27-8 N2-cyclopropyl-1,3,5-triazine-2,4,6-triamine Cyromazine C6H10N6 Nc2nc(N)nc(NC1CC1)n2 InChI=1S/C6H10N6/c7-4-10-5(8)12-6(11-4)9-3-1-2-3/h3H,1-2H2,(H5,7,8,9,10,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Greece Cyromazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyromazine 21Oct2008 2008 doi:10.2903/j.efsa.2008.168r
+Cyromazine 66215-27-8 single chemical entity Component is identical to the substance Cyromazine 66215-27-8 N2-cyclopropyl-1,3,5-triazine-2,4,6-triamine Cyromazine C6H10N6 Nc2nc(N)nc(NC1CC1)n2 InChI=1S/C6H10N6/c7-4-10-5(8)12-6(11-4)9-3-1-2-3/h3H,1-2H2,(H5,7,8,9,10,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Greece Cyromazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyromazine 21Oct2008 2008 doi:10.2903/j.efsa.2008.168r
+Cyromazine 66215-27-8 single chemical entity Component is identical to the substance Cyromazine 66215-27-8 N2-cyclopropyl-1,3,5-triazine-2,4,6-triamine Cyromazine C6H10N6 Nc2nc(N)nc(NC1CC1)n2 InChI=1S/C6H10N6/c7-4-10-5(8)12-6(11-4)9-3-1-2-3/h3H,1-2H2,(H5,7,8,9,10,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Greece Cyromazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyromazine 21Oct2008 2008 doi:10.2903/j.efsa.2008.168r
+Cyromazine 66215-27-8 single chemical entity Component is identical to the substance Cyromazine 66215-27-8 N2-cyclopropyl-1,3,5-triazine-2,4,6-triamine Cyromazine C6H10N6 Nc2nc(N)nc(NC1CC1)n2 InChI=1S/C6H10N6/c7-4-10-5(8)12-6(11-4)9-3-1-2-3/h3H,1-2H2,(H5,7,8,9,10,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Greece Cyromazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyromazine 21Oct2008 2008 doi:10.2903/j.efsa.2008.168r
+Cyromazine 66215-27-8 single chemical entity Component is identical to the substance Cyromazine 66215-27-8 N2-cyclopropyl-1,3,5-triazine-2,4,6-triamine Cyromazine C6H10N6 Nc2nc(N)nc(NC1CC1)n2 InChI=1S/C6H10N6/c7-4-10-5(8)12-6(11-4)9-3-1-2-3/h3H,1-2H2,(H5,7,8,9,10,11,12) organic compound Other Other gene mutation yeast cytogenetic assay in vitro According to OECD Guideline 480 (Genetic Toxicology: Saccharomyces cerevisiae, Gene Mutation Assay) No Acceptable Saccharomyces cerevisiae (as organism) D7 Not reported yes, concurrent vehicle with Negative RMS: Greece Cyromazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyromazine 21Oct2008 2008 doi:10.2903/j.efsa.2008.168r
+Cyromazine 66215-27-8 single chemical entity Component is identical to the substance Cyromazine 66215-27-8 N2-cyclopropyl-1,3,5-triazine-2,4,6-triamine Cyromazine C6H10N6 Nc2nc(N)nc(NC1CC1)n2 InChI=1S/C6H10N6/c7-4-10-5(8)12-6(11-4)9-3-1-2-3/h3H,1-2H2,(H5,7,8,9,10,11,12) organic compound Other Other gene mutation yeast cytogenetic assay in vitro According to OECD Guideline 480 (Genetic Toxicology: Saccharomyces cerevisiae, Gene Mutation Assay) No Acceptable Saccharomyces cerevisiae (as organism) D7 Not reported yes, concurrent vehicle without Negative RMS: Greece Cyromazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyromazine 21Oct2008 2008 doi:10.2903/j.efsa.2008.168r
+Cyromazine 66215-27-8 single chemical entity Component is identical to the substance Cyromazine 66215-27-8 N2-cyclopropyl-1,3,5-triazine-2,4,6-triamine Cyromazine C6H10N6 Nc2nc(N)nc(NC1CC1)n2 InChI=1S/C6H10N6/c7-4-10-5(8)12-6(11-4)9-3-1-2-3/h3H,1-2H2,(H5,7,8,9,10,11,12) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: Greece Cyromazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyromazine 21Oct2008 2008 doi:10.2903/j.efsa.2008.168r
+Cyromazine 66215-27-8 single chemical entity Component is identical to the substance Cyromazine 66215-27-8 N2-cyclopropyl-1,3,5-triazine-2,4,6-triamine Cyromazine C6H10N6 Nc2nc(N)nc(NC1CC1)n2 InChI=1S/C6H10N6/c7-4-10-5(8)12-6(11-4)9-3-1-2-3/h3H,1-2H2,(H5,7,8,9,10,11,12) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: Greece Cyromazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyromazine 21Oct2008 2008 doi:10.2903/j.efsa.2008.168r
+Cyromazine 66215-27-8 single chemical entity Component is identical to the substance Cyromazine 66215-27-8 N2-cyclopropyl-1,3,5-triazine-2,4,6-triamine Cyromazine C6H10N6 Nc2nc(N)nc(NC1CC1)n2 InChI=1S/C6H10N6/c7-4-10-5(8)12-6(11-4)9-3-1-2-3/h3H,1-2H2,(H5,7,8,9,10,11,12) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Greece Cyromazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyromazine 21Oct2008 2008 doi:10.2903/j.efsa.2008.168r
+Cyromazine 66215-27-8 single chemical entity Component is identical to the substance Cyromazine 66215-27-8 N2-cyclopropyl-1,3,5-triazine-2,4,6-triamine Cyromazine C6H10N6 Nc2nc(N)nc(NC1CC1)n2 InChI=1S/C6H10N6/c7-4-10-5(8)12-6(11-4)9-3-1-2-3/h3H,1-2H2,(H5,7,8,9,10,11,12) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Greece Cyromazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyromazine 21Oct2008 2008 doi:10.2903/j.efsa.2008.168r
+Cyromazine 66215-27-8 single chemical entity Component is identical to the substance Cyromazine 66215-27-8 N2-cyclopropyl-1,3,5-triazine-2,4,6-triamine Cyromazine C6H10N6 Nc2nc(N)nc(NC1CC1)n2 InChI=1S/C6H10N6/c7-4-10-5(8)12-6(11-4)9-3-1-2-3/h3H,1-2H2,(H5,7,8,9,10,11,12) organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable House mouse (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Greece Cyromazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyromazine 21Oct2008 2008 doi:10.2903/j.efsa.2008.168r
+Cyromazine 66215-27-8 single chemical entity Component is identical to the substance Cyromazine 66215-27-8 N2-cyclopropyl-1,3,5-triazine-2,4,6-triamine Cyromazine C6H10N6 Nc2nc(N)nc(NC1CC1)n2 InChI=1S/C6H10N6/c7-4-10-5(8)12-6(11-4)9-3-1-2-3/h3H,1-2H2,(H5,7,8,9,10,11,12) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable Hamster (as animal) Not reported 3 Male/Female oral: unspecified yes, concurrent vehicle not applicable Negative no evidence RMS: Greece Cyromazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyromazine 21Oct2008 2008 doi:10.2903/j.efsa.2008.168r
+Cyromazine 66215-27-8 single chemical entity Component is identical to the substance Cyromazine 66215-27-8 N2-cyclopropyl-1,3,5-triazine-2,4,6-triamine Cyromazine C6H10N6 Nc2nc(N)nc(NC1CC1)n2 InChI=1S/C6H10N6/c7-4-10-5(8)12-6(11-4)9-3-1-2-3/h3H,1-2H2,(H5,7,8,9,10,11,12) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 10 Male/Female oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Greece Cyromazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyromazine 21Oct2008 2008 doi:10.2903/j.efsa.2008.168r
+Cyromazine 66215-27-8 single chemical entity Component is identical to the substance Cyromazine 66215-27-8 N2-cyclopropyl-1,3,5-triazine-2,4,6-triamine Cyromazine C6H10N6 Nc2nc(N)nc(NC1CC1)n2 InChI=1S/C6H10N6/c7-4-10-5(8)12-6(11-4)9-3-1-2-3/h3H,1-2H2,(H5,7,8,9,10,11,12) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 10 Male/Female oral: unspecified 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Greece Cyromazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyromazine 21Oct2008 2008 doi:10.2903/j.efsa.2008.168r
+Cyromazine 66215-27-8 single chemical entity Component is identical to the substance Cyromazine 66215-27-8 N2-cyclopropyl-1,3,5-triazine-2,4,6-triamine Cyromazine C6H10N6 Nc2nc(N)nc(NC1CC1)n2 InChI=1S/C6H10N6/c7-4-10-5(8)12-6(11-4)9-3-1-2-3/h3H,1-2H2,(H5,7,8,9,10,11,12) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 10 Male/Female oral: unspecified 72.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Greece Cyromazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyromazine 21Oct2008 2008 doi:10.2903/j.efsa.2008.168r
+Cyromazine 66215-27-8 single chemical entity Component is identical to the substance Cyromazine 66215-27-8 N2-cyclopropyl-1,3,5-triazine-2,4,6-triamine Cyromazine C6H10N6 Nc2nc(N)nc(NC1CC1)n2 InChI=1S/C6H10N6/c7-4-10-5(8)12-6(11-4)9-3-1-2-3/h3H,1-2H2,(H5,7,8,9,10,11,12) organic compound Other Other gene mutation mouse spot test in vivo Equivalent or similar to OECD Guideline 484 (Genetic Toxicology: Mouse Spot Test) Yes Acceptable House mouse (as animal) C57BL 71 Female intraperitoneal 8.0000000000 week yes, concurrent vehicle not applicable Inconclusive RMS: Greece Cyromazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyromazine 21Oct2008 2008 doi:10.2903/j.efsa.2008.168r
+Dicloran 202-746-4 99-30-9 single chemical entity Component is identical to the substance Dicloran 202-746-4 99-30-9 2,6-dichloro-4-nitroaniline Dicloran C6H4Cl2N2O2 Nc1c(Cl)cc(cc1Cl)[N+](=O)[O-] InChI=1/C6H4Cl2N2O2/c7-4-1-3(10(11)12)2-5(8)6(4)9/h1-2H,9H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Positive RMS: Spain Dicloran 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicloran 03Aug2010 2010 doi:10.2903/j.efsa.2010.1698
+Dicloran 202-746-4 99-30-9 single chemical entity Component is identical to the substance Dicloran 202-746-4 99-30-9 2,6-dichloro-4-nitroaniline Dicloran C6H4Cl2N2O2 Nc1c(Cl)cc(cc1Cl)[N+](=O)[O-] InChI=1/C6H4Cl2N2O2/c7-4-1-3(10(11)12)2-5(8)6(4)9/h1-2H,9H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Spain Dicloran 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicloran 03Aug2010 2010 doi:10.2903/j.efsa.2010.1698
+Dicloran 202-746-4 99-30-9 single chemical entity Component is identical to the substance Dicloran 202-746-4 99-30-9 2,6-dichloro-4-nitroaniline Dicloran C6H4Cl2N2O2 Nc1c(Cl)cc(cc1Cl)[N+](=O)[O-] InChI=1/C6H4Cl2N2O2/c7-4-1-3(10(11)12)2-5(8)6(4)9/h1-2H,9H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Spain Dicloran 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicloran 03Aug2010 2010 doi:10.2903/j.efsa.2010.1698
+Dicloran 202-746-4 99-30-9 single chemical entity Component is identical to the substance Dicloran 202-746-4 99-30-9 2,6-dichloro-4-nitroaniline Dicloran C6H4Cl2N2O2 Nc1c(Cl)cc(cc1Cl)[N+](=O)[O-] InChI=1/C6H4Cl2N2O2/c7-4-1-3(10(11)12)2-5(8)6(4)9/h1-2H,9H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Positive RMS: Spain Dicloran 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicloran 03Aug2010 2010 doi:10.2903/j.efsa.2010.1698
+Dicloran 202-746-4 99-30-9 single chemical entity Component is identical to the substance Dicloran 202-746-4 99-30-9 2,6-dichloro-4-nitroaniline Dicloran C6H4Cl2N2O2 Nc1c(Cl)cc(cc1Cl)[N+](=O)[O-] InChI=1/C6H4Cl2N2O2/c7-4-1-3(10(11)12)2-5(8)6(4)9/h1-2H,9H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Positive RMS: Spain Dicloran 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicloran 03Aug2010 2010 doi:10.2903/j.efsa.2010.1698
+Dicloran 202-746-4 99-30-9 single chemical entity Component is identical to the substance Dicloran 202-746-4 99-30-9 2,6-dichloro-4-nitroaniline Dicloran C6H4Cl2N2O2 Nc1c(Cl)cc(cc1Cl)[N+](=O)[O-] InChI=1/C6H4Cl2N2O2/c7-4-1-3(10(11)12)2-5(8)6(4)9/h1-2H,9H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Positive RMS: Spain Dicloran 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicloran 03Aug2010 2010 doi:10.2903/j.efsa.2010.1698
+Dicloran 202-746-4 99-30-9 single chemical entity Component is identical to the substance Dicloran 202-746-4 99-30-9 2,6-dichloro-4-nitroaniline Dicloran C6H4Cl2N2O2 Nc1c(Cl)cc(cc1Cl)[N+](=O)[O-] InChI=1/C6H4Cl2N2O2/c7-4-1-3(10(11)12)2-5(8)6(4)9/h1-2H,9H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Positive RMS: Spain Dicloran 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicloran 03Aug2010 2010 doi:10.2903/j.efsa.2010.1698
+Dicloran 202-746-4 99-30-9 single chemical entity Component is identical to the substance Dicloran 202-746-4 99-30-9 2,6-dichloro-4-nitroaniline Dicloran C6H4Cl2N2O2 Nc1c(Cl)cc(cc1Cl)[N+](=O)[O-] InChI=1/C6H4Cl2N2O2/c7-4-1-3(10(11)12)2-5(8)6(4)9/h1-2H,9H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Spain Dicloran 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicloran 03Aug2010 2010 doi:10.2903/j.efsa.2010.1698
+Dicloran 202-746-4 99-30-9 single chemical entity Component is identical to the substance Dicloran 202-746-4 99-30-9 2,6-dichloro-4-nitroaniline Dicloran C6H4Cl2N2O2 Nc1c(Cl)cc(cc1Cl)[N+](=O)[O-] InChI=1/C6H4Cl2N2O2/c7-4-1-3(10(11)12)2-5(8)6(4)9/h1-2H,9H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Spain Dicloran 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicloran 03Aug2010 2010 doi:10.2903/j.efsa.2010.1698
+Dicloran 202-746-4 99-30-9 single chemical entity Component is identical to the substance Dicloran 202-746-4 99-30-9 2,6-dichloro-4-nitroaniline Dicloran C6H4Cl2N2O2 Nc1c(Cl)cc(cc1Cl)[N+](=O)[O-] InChI=1/C6H4Cl2N2O2/c7-4-1-3(10(11)12)2-5(8)6(4)9/h1-2H,9H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Spain Dicloran 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicloran 03Aug2010 2010 doi:10.2903/j.efsa.2010.1698
+Dicloran 202-746-4 99-30-9 single chemical entity Component is identical to the substance Dicloran 202-746-4 99-30-9 2,6-dichloro-4-nitroaniline Dicloran C6H4Cl2N2O2 Nc1c(Cl)cc(cc1Cl)[N+](=O)[O-] InChI=1/C6H4Cl2N2O2/c7-4-1-3(10(11)12)2-5(8)6(4)9/h1-2H,9H2 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Ambiguous RMS: Spain Dicloran 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicloran 03Aug2010 2010 doi:10.2903/j.efsa.2010.1698
+Dicloran 202-746-4 99-30-9 single chemical entity Component is identical to the substance Dicloran 202-746-4 99-30-9 2,6-dichloro-4-nitroaniline Dicloran C6H4Cl2N2O2 Nc1c(Cl)cc(cc1Cl)[N+](=O)[O-] InChI=1/C6H4Cl2N2O2/c7-4-1-3(10(11)12)2-5(8)6(4)9/h1-2H,9H2 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: Spain Dicloran 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicloran 03Aug2010 2010 doi:10.2903/j.efsa.2010.1698
+Dicloran 202-746-4 99-30-9 single chemical entity Component is identical to the substance Dicloran 202-746-4 99-30-9 2,6-dichloro-4-nitroaniline Dicloran C6H4Cl2N2O2 Nc1c(Cl)cc(cc1Cl)[N+](=O)[O-] InChI=1/C6H4Cl2N2O2/c7-4-1-3(10(11)12)2-5(8)6(4)9/h1-2H,9H2 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes with Negative RMS: Spain Dicloran 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicloran 03Aug2010 2010 doi:10.2903/j.efsa.2010.1698
+Dicloran 202-746-4 99-30-9 single chemical entity Component is identical to the substance Dicloran 202-746-4 99-30-9 2,6-dichloro-4-nitroaniline Dicloran C6H4Cl2N2O2 Nc1c(Cl)cc(cc1Cl)[N+](=O)[O-] InChI=1/C6H4Cl2N2O2/c7-4-1-3(10(11)12)2-5(8)6(4)9/h1-2H,9H2 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes without Ambiguous RMS: Spain Dicloran 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicloran 03Aug2010 2010 doi:10.2903/j.efsa.2010.1698
+Dicloran 202-746-4 99-30-9 single chemical entity Component is identical to the substance Dicloran 202-746-4 99-30-9 2,6-dichloro-4-nitroaniline Dicloran C6H4Cl2N2O2 Nc1c(Cl)cc(cc1Cl)[N+](=O)[O-] InChI=1/C6H4Cl2N2O2/c7-4-1-3(10(11)12)2-5(8)6(4)9/h1-2H,9H2 organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Spain Dicloran 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicloran 03Aug2010 2010 doi:10.2903/j.efsa.2010.1698
+Dicloran 202-746-4 99-30-9 single chemical entity Component is identical to the substance Dicloran 202-746-4 99-30-9 2,6-dichloro-4-nitroaniline Dicloran C6H4Cl2N2O2 Nc1c(Cl)cc(cc1Cl)[N+](=O)[O-] InChI=1/C6H4Cl2N2O2/c7-4-1-3(10(11)12)2-5(8)6(4)9/h1-2H,9H2 organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo Equivalent or similar to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) Yes Acceptable Rat (as animal) Wistar Male oral: gavage 2.0000000000 h yes not applicable Negative RMS: Spain Dicloran 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicloran 03Aug2010 2010 doi:10.2903/j.efsa.2010.1698
+Dicloran 202-746-4 99-30-9 single chemical entity Component is identical to the substance Dicloran 202-746-4 99-30-9 2,6-dichloro-4-nitroaniline Dicloran C6H4Cl2N2O2 Nc1c(Cl)cc(cc1Cl)[N+](=O)[O-] InChI=1/C6H4Cl2N2O2/c7-4-1-3(10(11)12)2-5(8)6(4)9/h1-2H,9H2 organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo Equivalent or similar to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) Yes Acceptable Rat (as animal) Wistar Male oral: gavage 16.0000000000 h yes not applicable Negative RMS: Spain Dicloran 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicloran 03Aug2010 2010 doi:10.2903/j.efsa.2010.1698
+Dicloran 202-746-4 99-30-9 single chemical entity Component is identical to the substance Dicloran 202-746-4 99-30-9 2,6-dichloro-4-nitroaniline Dicloran C6H4Cl2N2O2 Nc1c(Cl)cc(cc1Cl)[N+](=O)[O-] InChI=1/C6H4Cl2N2O2/c7-4-1-3(10(11)12)2-5(8)6(4)9/h1-2H,9H2 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Spain Dicloran (Addendum II) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicloran 03Aug2010 2010 doi:10.2903/j.efsa.2010.1698
+Didecyldimethylammonium chloride 230-525-2 7173-51-5 single chemical entity Component is identical to the substance Didecyldimethylammonium chloride 230-525-2 7173-51-5 N-decyl-N,N-dimethyldecan-1-aminium chloride Didecyldimethylammonium chloride (mixture of alkyl-quaternary ammonium salts with alkyl chain lengths of C8, C10 and C12) C22H48N.Cl [Cl-].CCCCCCCCCC[N+](C)(C)CCCCCCCCCC InChI=1/C22H48N.ClH/c1-5-7-9-11-13-15-17-19-21-23(3,4)22-20-18-16-14-12-10-8-6-2;/h5-22H2,1-4H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes without Negative RMS: The Netherlands Didecyldimethylammonium Chloride 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance didecyldimethylammonium chloride 03Apr2009 2009 doi: 10.2903/j.efsa.2009.214r
+Didecyldimethylammonium chloride 230-525-2 7173-51-5 single chemical entity Component is identical to the substance Didecyldimethylammonium chloride 230-525-2 7173-51-5 N-decyl-N,N-dimethyldecan-1-aminium chloride Didecyldimethylammonium chloride (mixture of alkyl-quaternary ammonium salts with alkyl chain lengths of C8, C10 and C12) C22H48N.Cl [Cl-].CCCCCCCCCC[N+](C)(C)CCCCCCCCCC InChI=1/C22H48N.ClH/c1-5-7-9-11-13-15-17-19-21-23(3,4)22-20-18-16-14-12-10-8-6-2;/h5-22H2,1-4H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The Netherlands Didecyldimethylammonium Chloride 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance didecyldimethylammonium chloride 03Apr2009 2009 doi: 10.2903/j.efsa.2009.214r
+Didecyldimethylammonium chloride 230-525-2 7173-51-5 single chemical entity Component is identical to the substance Didecyldimethylammonium chloride 230-525-2 7173-51-5 N-decyl-N,N-dimethyldecan-1-aminium chloride Didecyldimethylammonium chloride (mixture of alkyl-quaternary ammonium salts with alkyl chain lengths of C8, C10 and C12) C22H48N.Cl [Cl-].CCCCCCCCCC[N+](C)(C)CCCCCCCCCC InChI=1/C22H48N.ClH/c1-5-7-9-11-13-15-17-19-21-23(3,4)22-20-18-16-14-12-10-8-6-2;/h5-22H2,1-4H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The Netherlands Didecyldimethylammonium Chloride 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance didecyldimethylammonium chloride 03Apr2009 2009 doi: 10.2903/j.efsa.2009.214r
+Didecyldimethylammonium chloride 230-525-2 7173-51-5 single chemical entity Component is identical to the substance Didecyldimethylammonium chloride 230-525-2 7173-51-5 N-decyl-N,N-dimethyldecan-1-aminium chloride Didecyldimethylammonium chloride (mixture of alkyl-quaternary ammonium salts with alkyl chain lengths of C8, C10 and C12) C22H48N.Cl [Cl-].CCCCCCCCCC[N+](C)(C)CCCCCCCCCC InChI=1/C22H48N.ClH/c1-5-7-9-11-13-15-17-19-21-23(3,4)22-20-18-16-14-12-10-8-6-2;/h5-22H2,1-4H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The Netherlands Didecyldimethylammonium Chloride 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance didecyldimethylammonium chloride 03Apr2009 2009 doi: 10.2903/j.efsa.2009.214r
+Didecyldimethylammonium chloride 230-525-2 7173-51-5 single chemical entity Component is identical to the substance Didecyldimethylammonium chloride 230-525-2 7173-51-5 N-decyl-N,N-dimethyldecan-1-aminium chloride Didecyldimethylammonium chloride (mixture of alkyl-quaternary ammonium salts with alkyl chain lengths of C8, C10 and C12) C22H48N.Cl [Cl-].CCCCCCCCCC[N+](C)(C)CCCCCCCCCC InChI=1/C22H48N.ClH/c1-5-7-9-11-13-15-17-19-21-23(3,4)22-20-18-16-14-12-10-8-6-2;/h5-22H2,1-4H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The Netherlands Didecyldimethylammonium Chloride 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance didecyldimethylammonium chloride 03Apr2009 2009 doi: 10.2903/j.efsa.2009.214r
+Didecyldimethylammonium chloride 230-525-2 7173-51-5 single chemical entity Component is identical to the substance Didecyldimethylammonium chloride 230-525-2 7173-51-5 N-decyl-N,N-dimethyldecan-1-aminium chloride Didecyldimethylammonium chloride (mixture of alkyl-quaternary ammonium salts with alkyl chain lengths of C8, C10 and C12) C22H48N.Cl [Cl-].CCCCCCCCCC[N+](C)(C)CCCCCCCCCC InChI=1/C22H48N.ClH/c1-5-7-9-11-13-15-17-19-21-23(3,4)22-20-18-16-14-12-10-8-6-2;/h5-22H2,1-4H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The Netherlands Didecyldimethylammonium Chloride 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance didecyldimethylammonium chloride 03Apr2009 2009 doi: 10.2903/j.efsa.2009.214r
+Didecyldimethylammonium chloride 230-525-2 7173-51-5 single chemical entity Component is identical to the substance Didecyldimethylammonium chloride 230-525-2 7173-51-5 N-decyl-N,N-dimethyldecan-1-aminium chloride Didecyldimethylammonium chloride (mixture of alkyl-quaternary ammonium salts with alkyl chain lengths of C8, C10 and C12) C22H48N.Cl [Cl-].CCCCCCCCCC[N+](C)(C)CCCCCCCCCC InChI=1/C22H48N.ClH/c1-5-7-9-11-13-15-17-19-21-23(3,4)22-20-18-16-14-12-10-8-6-2;/h5-22H2,1-4H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes with Negative RMS: The Netherlands Didecyldimethylammonium Chloride 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance didecyldimethylammonium chloride 03Apr2009 2009 doi: 10.2903/j.efsa.2009.214r
+Didecyldimethylammonium chloride 230-525-2 7173-51-5 single chemical entity Component is identical to the substance Didecyldimethylammonium chloride 230-525-2 7173-51-5 N-decyl-N,N-dimethyldecan-1-aminium chloride Didecyldimethylammonium chloride (mixture of alkyl-quaternary ammonium salts with alkyl chain lengths of C8, C10 and C12) C22H48N.Cl [Cl-].CCCCCCCCCC[N+](C)(C)CCCCCCCCCC InChI=1/C22H48N.ClH/c1-5-7-9-11-13-15-17-19-21-23(3,4)22-20-18-16-14-12-10-8-6-2;/h5-22H2,1-4H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The Netherlands Didecyldimethylammonium Chloride 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance didecyldimethylammonium chloride 03Apr2009 2009 doi: 10.2903/j.efsa.2009.214r
+Didecyldimethylammonium chloride 230-525-2 7173-51-5 single chemical entity Component is identical to the substance Didecyldimethylammonium chloride 230-525-2 7173-51-5 N-decyl-N,N-dimethyldecan-1-aminium chloride Didecyldimethylammonium chloride (mixture of alkyl-quaternary ammonium salts with alkyl chain lengths of C8, C10 and C12) C22H48N.Cl [Cl-].CCCCCCCCCC[N+](C)(C)CCCCCCCCCC InChI=1/C22H48N.ClH/c1-5-7-9-11-13-15-17-19-21-23(3,4)22-20-18-16-14-12-10-8-6-2;/h5-22H2,1-4H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The Netherlands Didecyldimethylammonium Chloride 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance didecyldimethylammonium chloride 03Apr2009 2009 doi: 10.2903/j.efsa.2009.214r
+Didecyldimethylammonium chloride 230-525-2 7173-51-5 single chemical entity Component is identical to the substance Didecyldimethylammonium chloride 230-525-2 7173-51-5 N-decyl-N,N-dimethyldecan-1-aminium chloride Didecyldimethylammonium chloride (mixture of alkyl-quaternary ammonium salts with alkyl chain lengths of C8, C10 and C12) C22H48N.Cl [Cl-].CCCCCCCCCC[N+](C)(C)CCCCCCCCCC InChI=1/C22H48N.ClH/c1-5-7-9-11-13-15-17-19-21-23(3,4)22-20-18-16-14-12-10-8-6-2;/h5-22H2,1-4H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The Netherlands Didecyldimethylammonium Chloride 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance didecyldimethylammonium chloride 03Apr2009 2009 doi: 10.2903/j.efsa.2009.214r
+Didecyldimethylammonium chloride 230-525-2 7173-51-5 single chemical entity Component is identical to the substance Didecyldimethylammonium chloride 230-525-2 7173-51-5 N-decyl-N,N-dimethyldecan-1-aminium chloride Didecyldimethylammonium chloride (mixture of alkyl-quaternary ammonium salts with alkyl chain lengths of C8, C10 and C12) C22H48N.Cl [Cl-].CCCCCCCCCC[N+](C)(C)CCCCCCCCCC InChI=1/C22H48N.ClH/c1-5-7-9-11-13-15-17-19-21-23(3,4)22-20-18-16-14-12-10-8-6-2;/h5-22H2,1-4H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: The Netherlands Didecyldimethylammonium Chloride 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance didecyldimethylammonium chloride 03Apr2009 2009 doi: 10.2903/j.efsa.2009.214r
+Didecyldimethylammonium chloride 230-525-2 7173-51-5 single chemical entity Component is identical to the substance Didecyldimethylammonium chloride 230-525-2 7173-51-5 N-decyl-N,N-dimethyldecan-1-aminium chloride Didecyldimethylammonium chloride (mixture of alkyl-quaternary ammonium salts with alkyl chain lengths of C8, C10 and C12) C22H48N.Cl [Cl-].CCCCCCCCCC[N+](C)(C)CCCCCCCCCC InChI=1/C22H48N.ClH/c1-5-7-9-11-13-15-17-19-21-23(3,4)22-20-18-16-14-12-10-8-6-2;/h5-22H2,1-4H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: The Netherlands Didecyldimethylammonium Chloride 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance didecyldimethylammonium chloride 03Apr2009 2009 doi: 10.2903/j.efsa.2009.214r
+Didecyldimethylammonium chloride 230-525-2 7173-51-5 single chemical entity Component is identical to the substance Didecyldimethylammonium chloride 230-525-2 7173-51-5 N-decyl-N,N-dimethyldecan-1-aminium chloride Didecyldimethylammonium chloride (mixture of alkyl-quaternary ammonium salts with alkyl chain lengths of C8, C10 and C12) C22H48N.Cl [Cl-].CCCCCCCCCC[N+](C)(C)CCCCCCCCCC InChI=1/C22H48N.ClH/c1-5-7-9-11-13-15-17-19-21-23(3,4)22-20-18-16-14-12-10-8-6-2;/h5-22H2,1-4H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Didecyldimethylammonium Chloride 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance didecyldimethylammonium chloride 03Apr2009 2009 doi: 10.2903/j.efsa.2009.214r
+Didecyldimethylammonium chloride 230-525-2 7173-51-5 single chemical entity Component is identical to the substance Didecyldimethylammonium chloride 230-525-2 7173-51-5 N-decyl-N,N-dimethyldecan-1-aminium chloride Didecyldimethylammonium chloride (mixture of alkyl-quaternary ammonium salts with alkyl chain lengths of C8, C10 and C12) C22H48N.Cl [Cl-].CCCCCCCCCC[N+](C)(C)CCCCCCCCCC InChI=1/C22H48N.ClH/c1-5-7-9-11-13-15-17-19-21-23(3,4)22-20-18-16-14-12-10-8-6-2;/h5-22H2,1-4H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Didecyldimethylammonium Chloride 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance didecyldimethylammonium chloride 03Apr2009 2009 doi: 10.2903/j.efsa.2009.214r
+Didecyldimethylammonium chloride 230-525-2 7173-51-5 single chemical entity Component is identical to the substance Didecyldimethylammonium chloride 230-525-2 7173-51-5 N-decyl-N,N-dimethyldecan-1-aminium chloride Didecyldimethylammonium chloride (mixture of alkyl-quaternary ammonium salts with alkyl chain lengths of C8, C10 and C12) C22H48N.Cl [Cl-].CCCCCCCCCC[N+](C)(C)CCCCCCCCCC InChI=1/C22H48N.ClH/c1-5-7-9-11-13-15-17-19-21-23(3,4)22-20-18-16-14-12-10-8-6-2;/h5-22H2,1-4H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable Rat (as animal) Sprague-Dawley 10 Male/Female oral: unspecified 6.0000000000 h yes not applicable Negative no evidence RMS: The Netherlands Didecyldimethylammonium Chloride 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance didecyldimethylammonium chloride 03Apr2009 2009 doi: 10.2903/j.efsa.2009.214r
+Didecyldimethylammonium chloride 230-525-2 7173-51-5 single chemical entity Component is identical to the substance Didecyldimethylammonium chloride 230-525-2 7173-51-5 N-decyl-N,N-dimethyldecan-1-aminium chloride Didecyldimethylammonium chloride (mixture of alkyl-quaternary ammonium salts with alkyl chain lengths of C8, C10 and C12) C22H48N.Cl [Cl-].CCCCCCCCCC[N+](C)(C)CCCCCCCCCC InChI=1/C22H48N.ClH/c1-5-7-9-11-13-15-17-19-21-23(3,4)22-20-18-16-14-12-10-8-6-2;/h5-22H2,1-4H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable Rat (as animal) Sprague-Dawley 10 Male/Female oral: unspecified 24.0000000000 h yes not applicable Negative no evidence RMS: The Netherlands Didecyldimethylammonium Chloride 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance didecyldimethylammonium chloride 03Apr2009 2009 doi: 10.2903/j.efsa.2009.214r
+Didecyldimethylammonium chloride 230-525-2 7173-51-5 single chemical entity Component is identical to the substance Didecyldimethylammonium chloride 230-525-2 7173-51-5 N-decyl-N,N-dimethyldecan-1-aminium chloride Didecyldimethylammonium chloride (mixture of alkyl-quaternary ammonium salts with alkyl chain lengths of C8, C10 and C12) C22H48N.Cl [Cl-].CCCCCCCCCC[N+](C)(C)CCCCCCCCCC InChI=1/C22H48N.ClH/c1-5-7-9-11-13-15-17-19-21-23(3,4)22-20-18-16-14-12-10-8-6-2;/h5-22H2,1-4H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable Rat (as animal) Sprague-Dawley 10 Male/Female oral: unspecified 48.0000000000 h yes not applicable Negative no evidence RMS: The Netherlands Didecyldimethylammonium Chloride 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance didecyldimethylammonium chloride 03Apr2009 2009 doi: 10.2903/j.efsa.2009.214r
+Diazinon 206-373-8 333-41-5 single chemical entity Component is identical to the substance Diazinon 206-373-8 333-41-5 O,O-diethyl O-(2-isopropyl-6-methylpyrimidin-4-yl) thiophosphate Diazinon C12H21N2O3PS CCOP(=S)(OCC)Oc1cc(C)nc(n1)C(C)C InChI=1/C12H21N2O3PS/c1-6-15-18(19,16-7-2)17-11-8-10(5)13-12(14-11)9(3)4/h8-9H,6-7H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Portugal Diazinon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance diazinon 09Aug2006 2006 doi:10.2903/j.efsa.2006.85r
+Diazinon 206-373-8 333-41-5 single chemical entity Component is identical to the substance Diazinon 206-373-8 333-41-5 O,O-diethyl O-(2-isopropyl-6-methylpyrimidin-4-yl) thiophosphate Diazinon C12H21N2O3PS CCOP(=S)(OCC)Oc1cc(C)nc(n1)C(C)C InChI=1/C12H21N2O3PS/c1-6-15-18(19,16-7-2)17-11-8-10(5)13-12(14-11)9(3)4/h8-9H,6-7H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Portugal Diazinon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance diazinon 09Aug2006 2006 doi:10.2903/j.efsa.2006.85r
+Diazinon 206-373-8 333-41-5 single chemical entity Component is identical to the substance Diazinon 206-373-8 333-41-5 O,O-diethyl O-(2-isopropyl-6-methylpyrimidin-4-yl) thiophosphate Diazinon C12H21N2O3PS CCOP(=S)(OCC)Oc1cc(C)nc(n1)C(C)C InChI=1/C12H21N2O3PS/c1-6-15-18(19,16-7-2)17-11-8-10(5)13-12(14-11)9(3)4/h8-9H,6-7H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Portugal Diazinon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance diazinon 09Aug2006 2006 doi:10.2903/j.efsa.2006.85r
+Diazinon 206-373-8 333-41-5 single chemical entity Component is identical to the substance Diazinon 206-373-8 333-41-5 O,O-diethyl O-(2-isopropyl-6-methylpyrimidin-4-yl) thiophosphate Diazinon C12H21N2O3PS CCOP(=S)(OCC)Oc1cc(C)nc(n1)C(C)C InChI=1/C12H21N2O3PS/c1-6-15-18(19,16-7-2)17-11-8-10(5)13-12(14-11)9(3)4/h8-9H,6-7H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Portugal Diazinon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance diazinon 09Aug2006 2006 doi:10.2903/j.efsa.2006.85r
+Diazinon 206-373-8 333-41-5 single chemical entity Component is identical to the substance Diazinon 206-373-8 333-41-5 O,O-diethyl O-(2-isopropyl-6-methylpyrimidin-4-yl) thiophosphate Diazinon C12H21N2O3PS CCOP(=S)(OCC)Oc1cc(C)nc(n1)C(C)C InChI=1/C12H21N2O3PS/c1-6-15-18(19,16-7-2)17-11-8-10(5)13-12(14-11)9(3)4/h8-9H,6-7H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Portugal Diazinon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance diazinon 09Aug2006 2006 doi:10.2903/j.efsa.2006.85r
+Diazinon 206-373-8 333-41-5 single chemical entity Component is identical to the substance Diazinon 206-373-8 333-41-5 O,O-diethyl O-(2-isopropyl-6-methylpyrimidin-4-yl) thiophosphate Diazinon C12H21N2O3PS CCOP(=S)(OCC)Oc1cc(C)nc(n1)C(C)C InChI=1/C12H21N2O3PS/c1-6-15-18(19,16-7-2)17-11-8-10(5)13-12(14-11)9(3)4/h8-9H,6-7H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Portugal Diazinon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance diazinon 09Aug2006 2006 doi:10.2903/j.efsa.2006.85r
+Diazinon 206-373-8 333-41-5 single chemical entity Component is identical to the substance Diazinon 206-373-8 333-41-5 O,O-diethyl O-(2-isopropyl-6-methylpyrimidin-4-yl) thiophosphate Diazinon C12H21N2O3PS CCOP(=S)(OCC)Oc1cc(C)nc(n1)C(C)C InChI=1/C12H21N2O3PS/c1-6-15-18(19,16-7-2)17-11-8-10(5)13-12(14-11)9(3)4/h8-9H,6-7H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Portugal Diazinon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance diazinon 09Aug2006 2006 doi:10.2903/j.efsa.2006.85r
+Diazinon 206-373-8 333-41-5 single chemical entity Component is identical to the substance Diazinon 206-373-8 333-41-5 O,O-diethyl O-(2-isopropyl-6-methylpyrimidin-4-yl) thiophosphate Diazinon C12H21N2O3PS CCOP(=S)(OCC)Oc1cc(C)nc(n1)C(C)C InChI=1/C12H21N2O3PS/c1-6-15-18(19,16-7-2)17-11-8-10(5)13-12(14-11)9(3)4/h8-9H,6-7H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Portugal Diazinon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance diazinon 09Aug2006 2006 doi:10.2903/j.efsa.2006.85r
+Diazinon 206-373-8 333-41-5 single chemical entity Component is identical to the substance Diazinon 206-373-8 333-41-5 O,O-diethyl O-(2-isopropyl-6-methylpyrimidin-4-yl) thiophosphate Diazinon C12H21N2O3PS CCOP(=S)(OCC)Oc1cc(C)nc(n1)C(C)C InChI=1/C12H21N2O3PS/c1-6-15-18(19,16-7-2)17-11-8-10(5)13-12(14-11)9(3)4/h8-9H,6-7H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Portugal Diazinon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance diazinon 09Aug2006 2006 doi:10.2903/j.efsa.2006.85r
+Diazinon 206-373-8 333-41-5 single chemical entity Component is identical to the substance Diazinon 206-373-8 333-41-5 O,O-diethyl O-(2-isopropyl-6-methylpyrimidin-4-yl) thiophosphate Diazinon C12H21N2O3PS CCOP(=S)(OCC)Oc1cc(C)nc(n1)C(C)C InChI=1/C12H21N2O3PS/c1-6-15-18(19,16-7-2)17-11-8-10(5)13-12(14-11)9(3)4/h8-9H,6-7H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Portugal Diazinon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance diazinon 09Aug2006 2006 doi:10.2903/j.efsa.2006.85r
+Diazinon 206-373-8 333-41-5 single chemical entity Component is identical to the substance Diazinon 206-373-8 333-41-5 O,O-diethyl O-(2-isopropyl-6-methylpyrimidin-4-yl) thiophosphate Diazinon C12H21N2O3PS CCOP(=S)(OCC)Oc1cc(C)nc(n1)C(C)C InChI=1/C12H21N2O3PS/c1-6-15-18(19,16-7-2)17-11-8-10(5)13-12(14-11)9(3)4/h8-9H,6-7H2,1-5H3 organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes without Negative RMS: Portugal Diazinon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance diazinon 09Aug2006 2006 doi:10.2903/j.efsa.2006.85r
+Diazinon 206-373-8 333-41-5 single chemical entity Component is identical to the substance Diazinon 206-373-8 333-41-5 O,O-diethyl O-(2-isopropyl-6-methylpyrimidin-4-yl) thiophosphate Diazinon C12H21N2O3PS CCOP(=S)(OCC)Oc1cc(C)nc(n1)C(C)C InChI=1/C12H21N2O3PS/c1-6-15-18(19,16-7-2)17-11-8-10(5)13-12(14-11)9(3)4/h8-9H,6-7H2,1-5H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Portugal Diazinon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance diazinon 09Aug2006 2006 doi:10.2903/j.efsa.2006.85r
+Diazinon 206-373-8 333-41-5 single chemical entity Component is identical to the substance Diazinon 206-373-8 333-41-5 O,O-diethyl O-(2-isopropyl-6-methylpyrimidin-4-yl) thiophosphate Diazinon C12H21N2O3PS CCOP(=S)(OCC)Oc1cc(C)nc(n1)C(C)C InChI=1/C12H21N2O3PS/c1-6-15-18(19,16-7-2)17-11-8-10(5)13-12(14-11)9(3)4/h8-9H,6-7H2,1-5H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Portugal Diazinon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance diazinon 09Aug2006 2006 doi:10.2903/j.efsa.2006.85r
+Diazinon 206-373-8 333-41-5 single chemical entity Component is identical to the substance Diazinon 206-373-8 333-41-5 O,O-diethyl O-(2-isopropyl-6-methylpyrimidin-4-yl) thiophosphate Diazinon C12H21N2O3PS CCOP(=S)(OCC)Oc1cc(C)nc(n1)C(C)C InChI=1/C12H21N2O3PS/c1-6-15-18(19,16-7-2)17-11-8-10(5)13-12(14-11)9(3)4/h8-9H,6-7H2,1-5H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Portugal Diazinon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance diazinon 09Aug2006 2006 doi:10.2903/j.efsa.2006.85r
+Diazinon 206-373-8 333-41-5 single chemical entity Component is identical to the substance Diazinon 206-373-8 333-41-5 O,O-diethyl O-(2-isopropyl-6-methylpyrimidin-4-yl) thiophosphate Diazinon C12H21N2O3PS CCOP(=S)(OCC)Oc1cc(C)nc(n1)C(C)C InChI=1/C12H21N2O3PS/c1-6-15-18(19,16-7-2)17-11-8-10(5)13-12(14-11)9(3)4/h8-9H,6-7H2,1-5H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Portugal Diazinon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance diazinon 09Aug2006 2006 doi:10.2903/j.efsa.2006.85r
+Diazinon 206-373-8 333-41-5 single chemical entity Component is identical to the substance Diazinon 206-373-8 333-41-5 O,O-diethyl O-(2-isopropyl-6-methylpyrimidin-4-yl) thiophosphate Diazinon C12H21N2O3PS CCOP(=S)(OCC)Oc1cc(C)nc(n1)C(C)C InChI=1/C12H21N2O3PS/c1-6-15-18(19,16-7-2)17-11-8-10(5)13-12(14-11)9(3)4/h8-9H,6-7H2,1-5H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 16 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Portugal Diazinon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance diazinon 09Aug2006 2006 doi:10.2903/j.efsa.2006.85r
+Clofentezine 277-728-2 74115-24-5 single chemical entity Component is identical to the substance Clofentezine 277-728-2 74115-24-5 3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine Clofentezine C14H8Cl2N4 Clc3ccccc3c1nnc(nn1)c2ccccc2Cl InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Clofentezine 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine 20Jul2009 2009 doi:10.2903/j.efsa.2009.269r
+Clofentezine 277-728-2 74115-24-5 single chemical entity Component is identical to the substance Clofentezine 277-728-2 74115-24-5 3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine Clofentezine C14H8Cl2N4 Clc3ccccc3c1nnc(nn1)c2ccccc2Cl InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Clofentezine 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine 20Jul2009 2009 doi:10.2903/j.efsa.2009.269r
+Clofentezine 277-728-2 74115-24-5 single chemical entity Component is identical to the substance Clofentezine 277-728-2 74115-24-5 3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine Clofentezine C14H8Cl2N4 Clc3ccccc3c1nnc(nn1)c2ccccc2Cl InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Clofentezine 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine 20Jul2009 2009 doi:10.2903/j.efsa.2009.269r
+Clofentezine 277-728-2 74115-24-5 single chemical entity Component is identical to the substance Clofentezine 277-728-2 74115-24-5 3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine Clofentezine C14H8Cl2N4 Clc3ccccc3c1nnc(nn1)c2ccccc2Cl InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Clofentezine 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine 20Jul2009 2009 doi:10.2903/j.efsa.2009.269r
+Clofentezine 277-728-2 74115-24-5 single chemical entity Component is identical to the substance Clofentezine 277-728-2 74115-24-5 3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine Clofentezine C14H8Cl2N4 Clc3ccccc3c1nnc(nn1)c2ccccc2Cl InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Clofentezine 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine 20Jul2009 2009 doi:10.2903/j.efsa.2009.269r
+Clofentezine 277-728-2 74115-24-5 single chemical entity Component is identical to the substance Clofentezine 277-728-2 74115-24-5 3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine Clofentezine C14H8Cl2N4 Clc3ccccc3c1nnc(nn1)c2ccccc2Cl InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Clofentezine 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine 20Jul2009 2009 doi:10.2903/j.efsa.2009.269r
+Clofentezine 277-728-2 74115-24-5 single chemical entity Component is identical to the substance Clofentezine 277-728-2 74115-24-5 3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine Clofentezine C14H8Cl2N4 Clc3ccccc3c1nnc(nn1)c2ccccc2Cl InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Clofentezine 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine 20Jul2009 2009 doi:10.2903/j.efsa.2009.269r
+Clofentezine 277-728-2 74115-24-5 single chemical entity Component is identical to the substance Clofentezine 277-728-2 74115-24-5 3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine Clofentezine C14H8Cl2N4 Clc3ccccc3c1nnc(nn1)c2ccccc2Cl InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Clofentezine 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine 20Jul2009 2009 doi:10.2903/j.efsa.2009.269r
+Clofentezine 277-728-2 74115-24-5 single chemical entity Component is identical to the substance Clofentezine 277-728-2 74115-24-5 3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine Clofentezine C14H8Cl2N4 Clc3ccccc3c1nnc(nn1)c2ccccc2Cl InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Clofentezine 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine 20Jul2009 2009 doi:10.2903/j.efsa.2009.269r
+Clofentezine 277-728-2 74115-24-5 single chemical entity Component is identical to the substance Clofentezine 277-728-2 74115-24-5 3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine Clofentezine C14H8Cl2N4 Clc3ccccc3c1nnc(nn1)c2ccccc2Cl InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Clofentezine 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine 20Jul2009 2009 doi:10.2903/j.efsa.2009.269r
+Clofentezine 277-728-2 74115-24-5 single chemical entity Component is identical to the substance Clofentezine 277-728-2 74115-24-5 3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine Clofentezine C14H8Cl2N4 Clc3ccccc3c1nnc(nn1)c2ccccc2Cl InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Clofentezine 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine 20Jul2009 2009 doi:10.2903/j.efsa.2009.269r
+Clofentezine 277-728-2 74115-24-5 single chemical entity Component is identical to the substance Clofentezine 277-728-2 74115-24-5 3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine Clofentezine C14H8Cl2N4 Clc3ccccc3c1nnc(nn1)c2ccccc2Cl InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Clofentezine 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine 20Jul2009 2009 doi:10.2903/j.efsa.2009.269r
+Clofentezine 277-728-2 74115-24-5 single chemical entity Component is identical to the substance Clofentezine 277-728-2 74115-24-5 3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine Clofentezine C14H8Cl2N4 Clc3ccccc3c1nnc(nn1)c2ccccc2Cl InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: The United Kingdom Clofentezine 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine 20Jul2009 2009 doi:10.2903/j.efsa.2009.269r
+Clofentezine 277-728-2 74115-24-5 single chemical entity Component is identical to the substance Clofentezine 277-728-2 74115-24-5 3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine Clofentezine C14H8Cl2N4 Clc3ccccc3c1nnc(nn1)c2ccccc2Cl InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: The United Kingdom Clofentezine 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine 20Jul2009 2009 doi:10.2903/j.efsa.2009.269r
+Clofentezine 277-728-2 74115-24-5 single chemical entity Component is identical to the substance Clofentezine 277-728-2 74115-24-5 3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine Clofentezine C14H8Cl2N4 Clc3ccccc3c1nnc(nn1)c2ccccc2Cl InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H organic compound Other Other genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro According to OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay) No Acceptable Saccharomyces cerevisiae (as organism) D7 Not reported yes without Negative RMS: The United Kingdom Clofentezine 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine 20Jul2009 2009 doi:10.2903/j.efsa.2009.269r
+Clofentezine 277-728-2 74115-24-5 single chemical entity Component is identical to the substance Clofentezine 277-728-2 74115-24-5 3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine Clofentezine C14H8Cl2N4 Clc3ccccc3c1nnc(nn1)c2ccccc2Cl InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H organic compound Other Other genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro According to OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay) No Acceptable Saccharomyces cerevisiae (as organism) D7 Not reported yes with Negative RMS: The United Kingdom Clofentezine 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine 20Jul2009 2009 doi:10.2903/j.efsa.2009.269r
+Clofentezine 277-728-2 74115-24-5 single chemical entity Component is identical to the substance Clofentezine 277-728-2 74115-24-5 3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine Clofentezine C14H8Cl2N4 Clc3ccccc3c1nnc(nn1)c2ccccc2Cl InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H organic compound Other Other gene mutation yeast cytogenetic assay in vitro According to OECD Guideline 480 (Genetic Toxicology: Saccharomyces cerevisiae, Gene Mutation Assay) No Acceptable Saccharomyces cerevisiae (as organism) D7 Not reported yes with Negative RMS: The United Kingdom Clofentezine 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine 20Jul2009 2009 doi:10.2903/j.efsa.2009.269r
+Clofentezine 277-728-2 74115-24-5 single chemical entity Component is identical to the substance Clofentezine 277-728-2 74115-24-5 3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine Clofentezine C14H8Cl2N4 Clc3ccccc3c1nnc(nn1)c2ccccc2Cl InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H organic compound Other Other gene mutation yeast cytogenetic assay in vitro According to OECD Guideline 480 (Genetic Toxicology: Saccharomyces cerevisiae, Gene Mutation Assay) No Acceptable Saccharomyces cerevisiae (as organism) D7 Not reported yes without Negative RMS: The United Kingdom Clofentezine 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine 20Jul2009 2009 doi:10.2903/j.efsa.2009.269r
+Clofentezine 277-728-2 74115-24-5 single chemical entity Component is identical to the substance Clofentezine 277-728-2 74115-24-5 3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine Clofentezine C14H8Cl2N4 Clc3ccccc3c1nnc(nn1)c2ccccc2Cl InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Clofentezine 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine 20Jul2009 2009 doi:10.2903/j.efsa.2009.269r
+Clofentezine 277-728-2 74115-24-5 single chemical entity Component is identical to the substance Clofentezine 277-728-2 74115-24-5 3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine Clofentezine C14H8Cl2N4 Clc3ccccc3c1nnc(nn1)c2ccccc2Cl InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Clofentezine 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine 20Jul2009 2009 doi:10.2903/j.efsa.2009.269r
+Clofentezine 277-728-2 74115-24-5 single chemical entity Component is identical to the substance Clofentezine 277-728-2 74115-24-5 3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine Clofentezine C14H8Cl2N4 Clc3ccccc3c1nnc(nn1)c2ccccc2Cl InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Clofentezine 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine 20Jul2009 2009 doi:10.2903/j.efsa.2009.269r
+Clofentezine 277-728-2 74115-24-5 single chemical entity Component is identical to the substance Clofentezine 277-728-2 74115-24-5 3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine Clofentezine C14H8Cl2N4 Clc3ccccc3c1nnc(nn1)c2ccccc2Cl InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Clofentezine 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine 20Jul2009 2009 doi:10.2903/j.efsa.2009.269r
+Clofentezine 277-728-2 74115-24-5 single chemical entity Component is identical to the substance Clofentezine 277-728-2 74115-24-5 3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine Clofentezine C14H8Cl2N4 Clc3ccccc3c1nnc(nn1)c2ccccc2Cl InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 48.0000000000 h yes not applicable Negative no evidence RMS: The United Kingdom Clofentezine 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine 20Jul2009 2009 doi:10.2903/j.efsa.2009.269r
+Clofentezine 277-728-2 74115-24-5 single chemical entity Component is identical to the substance Clofentezine 277-728-2 74115-24-5 3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine Clofentezine C14H8Cl2N4 Clc3ccccc3c1nnc(nn1)c2ccccc2Cl InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 72.0000000000 h yes not applicable Negative no evidence RMS: The United Kingdom Clofentezine 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine 20Jul2009 2009 doi:10.2903/j.efsa.2009.269r
+Clofentezine 277-728-2 74115-24-5 single chemical entity Component is identical to the substance Clofentezine 277-728-2 74115-24-5 3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine Clofentezine C14H8Cl2N4 Clc3ccccc3c1nnc(nn1)c2ccccc2Cl InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes not applicable Negative no evidence RMS: The United Kingdom Clofentezine 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine 20Jul2009 2009 doi:10.2903/j.efsa.2009.269r
+Clofentezine 277-728-2 74115-24-5 single chemical entity Component is identical to the substance Clofentezine 277-728-2 74115-24-5 3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine Clofentezine C14H8Cl2N4 Clc3ccccc3c1nnc(nn1)c2ccccc2Cl InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 5 Male oral: unspecified 6.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The United Kingdom Clofentezine 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine 20Jul2009 2009 doi:10.2903/j.efsa.2009.269r
+Clofentezine 277-728-2 74115-24-5 single chemical entity Component is identical to the substance Clofentezine 277-728-2 74115-24-5 3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine Clofentezine C14H8Cl2N4 Clc3ccccc3c1nnc(nn1)c2ccccc2Cl InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H organic compound Other Other chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) Yes Acceptable Rat (as animal) Sprague-Dawley 30 Male oral: feed 10.0000000000 week yes not applicable Negative RMS: The United Kingdom Clofentezine 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine 20Jul2009 2009 doi:10.2903/j.efsa.2009.269r
+Clodinafop-propargyl 105512-06-9 single chemical entity Component is identical to the substance Clodinafop-propargyl 105512-06-9 prop-2-yn-1-yl (2R)-2-{4-[(5-chloro-3-fluoropyridin-2-yl)oxy]phenoxy}propanoate Clodinafop-Propargyl C17H13ClFNO4 O=C(OCC#C)[C@H](OC1=CC=C(OC2=NC=C(Cl)C=C2F)C=C1)C InChI=1S/C17H13ClFNO4/c1-3-8-22-17(21)11(2)23-13-4-6-14(7-5-13)24-16-15(19)9-12(18)10-20-16/h1,4-7,9-11H,8H2,2H3/t11-/m1/s1 organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes without Negative RMS: The Netherlands Clodinafop-propargyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clodinafop 31Aug2005 2005 doi:10.2903/j.efsa.2005.34ar
+Cymoxanil 261-043-0 57966-95-7 single chemical entity Component is identical to the substance Cymoxanil 261-043-0 57966-95-7 (1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide Cymoxanil C7H10N4O3 CCNC(=O)NC(=O)/C(=N/OC)/C#N InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+ organic representative isomer PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Austria Cymoxanil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil 17Oct2008 2008 doi:10.2903/j.efsa.2008.167r
+Cymoxanil 261-043-0 57966-95-7 single chemical entity Component is identical to the substance Cymoxanil 261-043-0 57966-95-7 (1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide Cymoxanil C7H10N4O3 CCNC(=O)NC(=O)/C(=N/OC)/C#N InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+ organic representative isomer PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Austria Cymoxanil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil 17Oct2008 2008 doi:10.2903/j.efsa.2008.167r
+Cymoxanil 261-043-0 57966-95-7 single chemical entity Component is identical to the substance Cymoxanil 261-043-0 57966-95-7 (1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide Cymoxanil C7H10N4O3 CCNC(=O)NC(=O)/C(=N/OC)/C#N InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+ organic representative isomer PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Austria Cymoxanil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil 17Oct2008 2008 doi:10.2903/j.efsa.2008.167r
+Cymoxanil 261-043-0 57966-95-7 single chemical entity Component is identical to the substance Cymoxanil 261-043-0 57966-95-7 (1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide Cymoxanil C7H10N4O3 CCNC(=O)NC(=O)/C(=N/OC)/C#N InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+ organic representative isomer PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Austria Cymoxanil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil 17Oct2008 2008 doi:10.2903/j.efsa.2008.167r
+Cymoxanil 261-043-0 57966-95-7 single chemical entity Component is identical to the substance Cymoxanil 261-043-0 57966-95-7 (1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide Cymoxanil C7H10N4O3 CCNC(=O)NC(=O)/C(=N/OC)/C#N InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+ organic representative isomer PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Austria Cymoxanil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil 17Oct2008 2008 doi:10.2903/j.efsa.2008.167r
+Cymoxanil 261-043-0 57966-95-7 single chemical entity Component is identical to the substance Cymoxanil 261-043-0 57966-95-7 (1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide Cymoxanil C7H10N4O3 CCNC(=O)NC(=O)/C(=N/OC)/C#N InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+ organic representative isomer PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Austria Cymoxanil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil 17Oct2008 2008 doi:10.2903/j.efsa.2008.167r
+Cymoxanil 261-043-0 57966-95-7 single chemical entity Component is identical to the substance Cymoxanil 261-043-0 57966-95-7 (1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide Cymoxanil C7H10N4O3 CCNC(=O)NC(=O)/C(=N/OC)/C#N InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+ organic representative isomer PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Austria Cymoxanil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil 17Oct2008 2008 doi:10.2903/j.efsa.2008.167r
+Cymoxanil 261-043-0 57966-95-7 single chemical entity Component is identical to the substance Cymoxanil 261-043-0 57966-95-7 (1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide Cymoxanil C7H10N4O3 CCNC(=O)NC(=O)/C(=N/OC)/C#N InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+ organic representative isomer PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Austria Cymoxanil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil 17Oct2008 2008 doi:10.2903/j.efsa.2008.167r
+Cymoxanil 261-043-0 57966-95-7 single chemical entity Component is identical to the substance Cymoxanil 261-043-0 57966-95-7 (1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide Cymoxanil C7H10N4O3 CCNC(=O)NC(=O)/C(=N/OC)/C#N InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+ organic representative isomer PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Austria Cymoxanil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil 17Oct2008 2008 doi:10.2903/j.efsa.2008.167r
+Cymoxanil 261-043-0 57966-95-7 single chemical entity Component is identical to the substance Cymoxanil 261-043-0 57966-95-7 (1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide Cymoxanil C7H10N4O3 CCNC(=O)NC(=O)/C(=N/OC)/C#N InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+ organic representative isomer PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Austria Cymoxanil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil 17Oct2008 2008 doi:10.2903/j.efsa.2008.167r
+Cymoxanil 261-043-0 57966-95-7 single chemical entity Component is identical to the substance Cymoxanil 261-043-0 57966-95-7 (1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide Cymoxanil C7H10N4O3 CCNC(=O)NC(=O)/C(=N/OC)/C#N InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+ organic representative isomer PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Austria Cymoxanil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil 17Oct2008 2008 doi:10.2903/j.efsa.2008.167r
+Cymoxanil 261-043-0 57966-95-7 single chemical entity Component is identical to the substance Cymoxanil 261-043-0 57966-95-7 (1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide Cymoxanil C7H10N4O3 CCNC(=O)NC(=O)/C(=N/OC)/C#N InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+ organic representative isomer PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Austria Cymoxanil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil 17Oct2008 2008 doi:10.2903/j.efsa.2008.167r
+Cymoxanil 261-043-0 57966-95-7 single chemical entity Component is identical to the substance Cymoxanil 261-043-0 57966-95-7 (1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide Cymoxanil C7H10N4O3 CCNC(=O)NC(=O)/C(=N/OC)/C#N InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+ organic representative isomer PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Austria Cymoxanil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil 17Oct2008 2008 doi:10.2903/j.efsa.2008.167r
+Cymoxanil 261-043-0 57966-95-7 single chemical entity Component is identical to the substance Cymoxanil 261-043-0 57966-95-7 (1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide Cymoxanil C7H10N4O3 CCNC(=O)NC(=O)/C(=N/OC)/C#N InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+ organic representative isomer PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Austria Cymoxanil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil 17Oct2008 2008 doi:10.2903/j.efsa.2008.167r
+Cymoxanil 261-043-0 57966-95-7 single chemical entity Component is identical to the substance Cymoxanil 261-043-0 57966-95-7 (1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide Cymoxanil C7H10N4O3 CCNC(=O)NC(=O)/C(=N/OC)/C#N InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+ organic representative isomer PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Austria Cymoxanil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil 17Oct2008 2008 doi:10.2903/j.efsa.2008.167r
+Cymoxanil 261-043-0 57966-95-7 single chemical entity Component is identical to the substance Cymoxanil 261-043-0 57966-95-7 (1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide Cymoxanil C7H10N4O3 CCNC(=O)NC(=O)/C(=N/OC)/C#N InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+ organic representative isomer PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Austria Cymoxanil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil 17Oct2008 2008 doi:10.2903/j.efsa.2008.167r
+Cymoxanil 261-043-0 57966-95-7 single chemical entity Component is identical to the substance Cymoxanil 261-043-0 57966-95-7 (1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide Cymoxanil C7H10N4O3 CCNC(=O)NC(=O)/C(=N/OC)/C#N InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+ organic representative isomer PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Austria Cymoxanil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil 17Oct2008 2008 doi:10.2903/j.efsa.2008.167r
+Cymoxanil 261-043-0 57966-95-7 single chemical entity Component is identical to the substance Cymoxanil 261-043-0 57966-95-7 (1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide Cymoxanil C7H10N4O3 CCNC(=O)NC(=O)/C(=N/OC)/C#N InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+ organic representative isomer PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Austria Cymoxanil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil 17Oct2008 2008 doi:10.2903/j.efsa.2008.167r
+Cymoxanil 261-043-0 57966-95-7 single chemical entity Component is identical to the substance Cymoxanil 261-043-0 57966-95-7 (1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide Cymoxanil C7H10N4O3 CCNC(=O)NC(=O)/C(=N/OC)/C#N InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+ organic representative isomer PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Austria Cymoxanil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil 17Oct2008 2008 doi:10.2903/j.efsa.2008.167r
+Cymoxanil 261-043-0 57966-95-7 single chemical entity Component is identical to the substance Cymoxanil 261-043-0 57966-95-7 (1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide Cymoxanil C7H10N4O3 CCNC(=O)NC(=O)/C(=N/OC)/C#N InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+ organic representative isomer PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Austria Cymoxanil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil 17Oct2008 2008 doi:10.2903/j.efsa.2008.167r
+Cymoxanil 261-043-0 57966-95-7 single chemical entity Component is identical to the substance Cymoxanil 261-043-0 57966-95-7 (1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide Cymoxanil C7H10N4O3 CCNC(=O)NC(=O)/C(=N/OC)/C#N InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+ organic representative isomer PubChem isomeric SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Austria Cymoxanil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil 17Oct2008 2008 doi:10.2903/j.efsa.2008.167r
+Cymoxanil 261-043-0 57966-95-7 single chemical entity Component is identical to the substance Cymoxanil 261-043-0 57966-95-7 (1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide Cymoxanil C7H10N4O3 CCNC(=O)NC(=O)/C(=N/OC)/C#N InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+ organic representative isomer PubChem isomeric SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Austria Cymoxanil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil 17Oct2008 2008 doi:10.2903/j.efsa.2008.167r
+Cymoxanil 261-043-0 57966-95-7 single chemical entity Component is identical to the substance Cymoxanil 261-043-0 57966-95-7 (1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide Cymoxanil C7H10N4O3 CCNC(=O)NC(=O)/C(=N/OC)/C#N InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+ organic representative isomer PubChem isomeric SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Austria Cymoxanil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil 17Oct2008 2008 doi:10.2903/j.efsa.2008.167r
+Cymoxanil 261-043-0 57966-95-7 single chemical entity Component is identical to the substance Cymoxanil 261-043-0 57966-95-7 (1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide Cymoxanil C7H10N4O3 CCNC(=O)NC(=O)/C(=N/OC)/C#N InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+ organic representative isomer PubChem isomeric SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Austria Cymoxanil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil 17Oct2008 2008 doi:10.2903/j.efsa.2008.167r
+Cymoxanil 261-043-0 57966-95-7 single chemical entity Component is identical to the substance Cymoxanil 261-043-0 57966-95-7 (1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide Cymoxanil C7H10N4O3 CCNC(=O)NC(=O)/C(=N/OC)/C#N InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+ organic representative isomer PubChem isomeric SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Positive RMS: Austria Cymoxanil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil 17Oct2008 2008 doi:10.2903/j.efsa.2008.167r
+Cymoxanil 261-043-0 57966-95-7 single chemical entity Component is identical to the substance Cymoxanil 261-043-0 57966-95-7 (1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide Cymoxanil C7H10N4O3 CCNC(=O)NC(=O)/C(=N/OC)/C#N InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+ organic representative isomer PubChem isomeric SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Positive RMS: Austria Cymoxanil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil 17Oct2008 2008 doi:10.2903/j.efsa.2008.167r
+Cymoxanil 261-043-0 57966-95-7 single chemical entity Component is identical to the substance Cymoxanil 261-043-0 57966-95-7 (1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide Cymoxanil C7H10N4O3 CCNC(=O)NC(=O)/C(=N/OC)/C#N InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+ organic representative isomer PubChem isomeric SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Austria Cymoxanil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil 17Oct2008 2008 doi:10.2903/j.efsa.2008.167r
+Cymoxanil 261-043-0 57966-95-7 single chemical entity Component is identical to the substance Cymoxanil 261-043-0 57966-95-7 (1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide Cymoxanil C7H10N4O3 CCNC(=O)NC(=O)/C(=N/OC)/C#N InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+ organic representative isomer PubChem isomeric SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Austria Cymoxanil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil 17Oct2008 2008 doi:10.2903/j.efsa.2008.167r
+Cymoxanil 261-043-0 57966-95-7 single chemical entity Component is identical to the substance Cymoxanil 261-043-0 57966-95-7 (1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide Cymoxanil C7H10N4O3 CCNC(=O)NC(=O)/C(=N/OC)/C#N InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+ organic representative isomer PubChem isomeric SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Positive RMS: Austria Cymoxanil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil 17Oct2008 2008 doi:10.2903/j.efsa.2008.167r
+Cymoxanil 261-043-0 57966-95-7 single chemical entity Component is identical to the substance Cymoxanil 261-043-0 57966-95-7 (1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide Cymoxanil C7H10N4O3 CCNC(=O)NC(=O)/C(=N/OC)/C#N InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+ organic representative isomer PubChem isomeric SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) ICR 10 Male/Female oral: gavage 72.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity$indirect evidence-systemic toxicity RMS: Austria Cymoxanil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil 17Oct2008 2008 doi:10.2903/j.efsa.2008.167r
+Cymoxanil 261-043-0 57966-95-7 single chemical entity Component is identical to the substance Cymoxanil 261-043-0 57966-95-7 (1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide Cymoxanil C7H10N4O3 CCNC(=O)NC(=O)/C(=N/OC)/C#N InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+ organic representative isomer PubChem isomeric SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) ICR 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity$indirect evidence-systemic toxicity RMS: Austria Cymoxanil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil 17Oct2008 2008 doi:10.2903/j.efsa.2008.167r
+Cymoxanil 261-043-0 57966-95-7 single chemical entity Component is identical to the substance Cymoxanil 261-043-0 57966-95-7 (1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide Cymoxanil C7H10N4O3 CCNC(=O)NC(=O)/C(=N/OC)/C#N InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+ organic representative isomer PubChem isomeric SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) ICR 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity$indirect evidence-systemic toxicity RMS: Austria Cymoxanil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil 17Oct2008 2008 doi:10.2903/j.efsa.2008.167r
+Cymoxanil 261-043-0 57966-95-7 single chemical entity Component is identical to the substance Cymoxanil 261-043-0 57966-95-7 (1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide Cymoxanil C7H10N4O3 CCNC(=O)NC(=O)/C(=N/OC)/C#N InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+ organic representative isomer PubChem isomeric SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Swiss 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity$indirect evidence-systemic toxicity RMS: Austria Cymoxanil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil 17Oct2008 2008 doi:10.2903/j.efsa.2008.167r
+Cymoxanil 261-043-0 57966-95-7 single chemical entity Component is identical to the substance Cymoxanil 261-043-0 57966-95-7 (1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide Cymoxanil C7H10N4O3 CCNC(=O)NC(=O)/C(=N/OC)/C#N InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+ organic representative isomer PubChem isomeric SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Sprague-Dawley 40 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Austria Cymoxanil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil 17Oct2008 2008 doi:10.2903/j.efsa.2008.167r
+Cymoxanil 261-043-0 57966-95-7 single chemical entity Component is identical to the substance Cymoxanil 261-043-0 57966-95-7 (1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide Cymoxanil C7H10N4O3 CCNC(=O)NC(=O)/C(=N/OC)/C#N InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+ organic representative isomer PubChem isomeric SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Sprague-Dawley 40 Male/Female oral: gavage 12.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Austria Cymoxanil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil 17Oct2008 2008 doi:10.2903/j.efsa.2008.167r
+Cymoxanil 261-043-0 57966-95-7 single chemical entity Component is identical to the substance Cymoxanil 261-043-0 57966-95-7 (1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide Cymoxanil C7H10N4O3 CCNC(=O)NC(=O)/C(=N/OC)/C#N InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+ organic representative isomer PubChem isomeric SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Sprague-Dawley 40 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Austria Cymoxanil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil 17Oct2008 2008 doi:10.2903/j.efsa.2008.167r
+Cymoxanil 261-043-0 57966-95-7 single chemical entity Component is identical to the substance Cymoxanil 261-043-0 57966-95-7 (1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide Cymoxanil C7H10N4O3 CCNC(=O)NC(=O)/C(=N/OC)/C#N InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+ organic representative isomer PubChem isomeric SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Sprague-Dawley 40 Male/Female oral: gavage 6.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Austria Cymoxanil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil 17Oct2008 2008 doi:10.2903/j.efsa.2008.167r
+Cymoxanil 261-043-0 57966-95-7 single chemical entity Component is identical to the substance Cymoxanil 261-043-0 57966-95-7 (1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide Cymoxanil C7H10N4O3 CCNC(=O)NC(=O)/C(=N/OC)/C#N InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+ organic representative isomer PubChem isomeric SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo Equivalent or similar to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) Yes Acceptable Rat (as animal) Crj:CD(SD) 5 Male oral: gavage 2.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Austria Cymoxanil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil 17Oct2008 2008 doi:10.2903/j.efsa.2008.167r
+Cymoxanil 261-043-0 57966-95-7 single chemical entity Component is identical to the substance Cymoxanil 261-043-0 57966-95-7 (1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide Cymoxanil C7H10N4O3 CCNC(=O)NC(=O)/C(=N/OC)/C#N InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+ organic representative isomer PubChem isomeric SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo Equivalent or similar to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) Yes Acceptable Rat (as animal) Crj:CD(SD) 5 Male oral: gavage 16.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Austria Cymoxanil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil 17Oct2008 2008 doi:10.2903/j.efsa.2008.167r
+Cymoxanil 261-043-0 57966-95-7 single chemical entity Component is identical to the substance Cymoxanil 261-043-0 57966-95-7 (1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide Cymoxanil C7H10N4O3 CCNC(=O)NC(=O)/C(=N/OC)/C#N InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+ organic representative isomer PubChem isomeric SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo Equivalent or similar to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) Yes Acceptable Rat (as animal) Crj:CD(SD) 5 Male oral: gavage 16.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Austria Cymoxanil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil 17Oct2008 2008 doi:10.2903/j.efsa.2008.167r
+Cymoxanil 261-043-0 57966-95-7 single chemical entity Component is identical to the substance Cymoxanil 261-043-0 57966-95-7 (1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide Cymoxanil C7H10N4O3 CCNC(=O)NC(=O)/C(=N/OC)/C#N InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+ organic representative isomer PubChem isomeric SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo Equivalent or similar to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) Yes Acceptable Rat (as animal) Crj:CD(SD) 5 Male oral: gavage 2.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Austria Cymoxanil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil 17Oct2008 2008 doi:10.2903/j.efsa.2008.167r
+Diquat 220-433-0 85-00-7 single chemical entity Component is identical to the substance Diquat 220-433-0 85-00-7 6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium Diquat C12H12N2+2 C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31 InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Diquat 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diquat 27Nov2015 2015 doi:10.2903/j.efsa.2015.4308
+Diquat 220-433-0 85-00-7 single chemical entity Component is identical to the substance Diquat 220-433-0 85-00-7 6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium Diquat C12H12N2+2 C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31 InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Diquat 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diquat 27Nov2015 2015 doi:10.2903/j.efsa.2015.4308
+Diquat 220-433-0 85-00-7 single chemical entity Component is identical to the substance Diquat 220-433-0 85-00-7 6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium Diquat C12H12N2+2 C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31 InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Diquat 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diquat 27Nov2015 2015 doi:10.2903/j.efsa.2015.4308
+Diquat 220-433-0 85-00-7 single chemical entity Component is identical to the substance Diquat 220-433-0 85-00-7 6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium Diquat C12H12N2+2 C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31 InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Diquat 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diquat 27Nov2015 2015 doi:10.2903/j.efsa.2015.4308
+Diquat 220-433-0 85-00-7 single chemical entity Component is identical to the substance Diquat 220-433-0 85-00-7 6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium Diquat C12H12N2+2 C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31 InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Diquat 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diquat 27Nov2015 2015 doi:10.2903/j.efsa.2015.4308
+Diquat 220-433-0 85-00-7 single chemical entity Component is identical to the substance Diquat 220-433-0 85-00-7 6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium Diquat C12H12N2+2 C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31 InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Diquat 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diquat 27Nov2015 2015 doi:10.2903/j.efsa.2015.4308
+Diquat 220-433-0 85-00-7 single chemical entity Component is identical to the substance Diquat 220-433-0 85-00-7 6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium Diquat C12H12N2+2 C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31 InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Diquat 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diquat 27Nov2015 2015 doi:10.2903/j.efsa.2015.4308
+Diquat 220-433-0 85-00-7 single chemical entity Component is identical to the substance Diquat 220-433-0 85-00-7 6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium Diquat C12H12N2+2 C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31 InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Diquat 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diquat 27Nov2015 2015 doi:10.2903/j.efsa.2015.4308
+Diquat 220-433-0 85-00-7 single chemical entity Component is identical to the substance Diquat 220-433-0 85-00-7 6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium Diquat C12H12N2+2 C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31 InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Diquat 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diquat 27Nov2015 2015 doi:10.2903/j.efsa.2015.4308
+Diquat 220-433-0 85-00-7 single chemical entity Component is identical to the substance Diquat 220-433-0 85-00-7 6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium Diquat C12H12N2+2 C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31 InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Diquat 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diquat 27Nov2015 2015 doi:10.2903/j.efsa.2015.4308
+Diquat 220-433-0 85-00-7 single chemical entity Component is identical to the substance Diquat 220-433-0 85-00-7 6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium Diquat C12H12N2+2 C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31 InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Diquat 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diquat 27Nov2015 2015 doi:10.2903/j.efsa.2015.4308
+Diquat 220-433-0 85-00-7 single chemical entity Component is identical to the substance Diquat 220-433-0 85-00-7 6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium Diquat C12H12N2+2 C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31 InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Diquat 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diquat 27Nov2015 2015 doi:10.2903/j.efsa.2015.4308
+Diquat 220-433-0 85-00-7 single chemical entity Component is identical to the substance Diquat 220-433-0 85-00-7 6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium Diquat C12H12N2+2 C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31 InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative no information RMS: The United Kingdom Diquat 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diquat 27Nov2015 2015 doi:10.2903/j.efsa.2015.4308
+Diquat 220-433-0 85-00-7 single chemical entity Component is identical to the substance Diquat 220-433-0 85-00-7 6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium Diquat C12H12N2+2 C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31 InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Negative no information RMS: The United Kingdom Diquat 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diquat 27Nov2015 2015 doi:10.2903/j.efsa.2015.4308
+Diquat 220-433-0 85-00-7 single chemical entity Component is identical to the substance Diquat 220-433-0 85-00-7 6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium Diquat C12H12N2+2 C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31 InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes without Ambiguous RMS: The United Kingdom Diquat 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diquat 27Nov2015 2015 doi:10.2903/j.efsa.2015.4308
+Diquat 220-433-0 85-00-7 single chemical entity Component is identical to the substance Diquat 220-433-0 85-00-7 6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium Diquat C12H12N2+2 C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31 InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes with Ambiguous RMS: The United Kingdom Diquat 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diquat 27Nov2015 2015 doi:10.2903/j.efsa.2015.4308
+Diquat 220-433-0 85-00-7 single chemical entity Component is identical to the substance Diquat 220-433-0 85-00-7 6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium Diquat C12H12N2+2 C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31 InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) C57BL 10 Male/Female oral: unspecified 48.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity RMS: The United Kingdom Diquat 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diquat 27Nov2015 2015 doi:10.2903/j.efsa.2015.4308
+Diquat 220-433-0 85-00-7 single chemical entity Component is identical to the substance Diquat 220-433-0 85-00-7 6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium Diquat C12H12N2+2 C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31 InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) C57BL 10 Male/Female oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity RMS: The United Kingdom Diquat 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diquat 27Nov2015 2015 doi:10.2903/j.efsa.2015.4308
+Diquat 220-433-0 85-00-7 single chemical entity Component is identical to the substance Diquat 220-433-0 85-00-7 6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium Diquat C12H12N2+2 C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31 InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) C57BL 10 Male/Female oral: unspecified 72.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity RMS: The United Kingdom Diquat 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diquat 27Nov2015 2015 doi:10.2903/j.efsa.2015.4308
+Diquat 220-433-0 85-00-7 single chemical entity Component is identical to the substance Diquat 220-433-0 85-00-7 6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium Diquat C12H12N2+2 C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31 InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Sprague-Dawley Male oral: unspecified 4.0000000000 h yes not applicable Negative RMS: The United Kingdom Diquat 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diquat 27Nov2015 2015 doi:10.2903/j.efsa.2015.4308
+Diquat 220-433-0 85-00-7 single chemical entity Component is identical to the substance Diquat 220-433-0 85-00-7 6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium Diquat C12H12N2+2 C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31 InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Sprague-Dawley Male oral: unspecified 12.0000000000 h yes not applicable Negative RMS: The United Kingdom Diquat 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diquat 27Nov2015 2015 doi:10.2903/j.efsa.2015.4308
+Diquat 220-433-0 85-00-7 single chemical entity Component is identical to the substance Diquat 220-433-0 85-00-7 6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium Diquat C12H12N2+2 C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31 InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) Yes Acceptable House mouse (as animal) CD-1 105 Male oral: gavage 5.0000000000 D yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Diquat 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diquat 27Nov2015 2015 doi:10.2903/j.efsa.2015.4308
+Diquat 220-433-0 85-00-7 single chemical entity Component is a metabolite of the substance 1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium 1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium Not in list C8H9N2O O=C1NCC[n+]2ccccc12 InChI=1/C8H8N2O/c11-8-7-3-1-2-5-10(7)6-4-9-8/h1-3,5H,4,6H2/p+1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: The United Kingdom Diquat 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diquat 27Nov2015 2015 doi:10.2903/j.efsa.2015.4308
+Diquat 220-433-0 85-00-7 single chemical entity Component is a metabolite of the substance 1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium 1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium Not in list C8H9N2O O=C1NCC[n+]2ccccc12 InChI=1/C8H8N2O/c11-8-7-3-1-2-5-10(7)6-4-9-8/h1-3,5H,4,6H2/p+1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: The United Kingdom Diquat 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diquat 27Nov2015 2015 doi:10.2903/j.efsa.2015.4308
+Diquat 220-433-0 85-00-7 single chemical entity Component is a metabolite of the substance 1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium 1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium Not in list C8H9N2O O=C1NCC[n+]2ccccc12 InChI=1/C8H8N2O/c11-8-7-3-1-2-5-10(7)6-4-9-8/h1-3,5H,4,6H2/p+1 organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported no data with Negative RMS: The United Kingdom Diquat 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diquat 27Nov2015 2015 doi:10.2903/j.efsa.2015.4308
+Diquat 220-433-0 85-00-7 single chemical entity Component is a metabolite of the substance 1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium 1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium Not in list C8H9N2O O=C1NCC[n+]2ccccc12 InChI=1/C8H8N2O/c11-8-7-3-1-2-5-10(7)6-4-9-8/h1-3,5H,4,6H2/p+1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: The United Kingdom Diquat 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diquat 27Nov2015 2015 doi:10.2903/j.efsa.2015.4308
+Diquat 220-433-0 85-00-7 single chemical entity Component is a metabolite of the substance 1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium 1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium Not in list C8H9N2O O=C1NCC[n+]2ccccc12 InChI=1/C8H8N2O/c11-8-7-3-1-2-5-10(7)6-4-9-8/h1-3,5H,4,6H2/p+1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: The United Kingdom Diquat 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diquat 27Nov2015 2015 doi:10.2903/j.efsa.2015.4308
+Diquat 220-433-0 85-00-7 single chemical entity Component is a metabolite of the substance 1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium 1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium Not in list C8H9N2O O=C1NCC[n+]2ccccc12 InChI=1/C8H8N2O/c11-8-7-3-1-2-5-10(7)6-4-9-8/h1-3,5H,4,6H2/p+1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: The United Kingdom Diquat 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diquat 27Nov2015 2015 doi:10.2903/j.efsa.2015.4308
+Diquat 220-433-0 85-00-7 single chemical entity Component is a metabolite of the substance 1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium 1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium Not in list C8H9N2O O=C1NCC[n+]2ccccc12 InChI=1/C8H8N2O/c11-8-7-3-1-2-5-10(7)6-4-9-8/h1-3,5H,4,6H2/p+1 organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported no data without Negative RMS: The United Kingdom Diquat 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diquat 27Nov2015 2015 doi:10.2903/j.efsa.2015.4308
+Diquat 220-433-0 85-00-7 single chemical entity Component is a metabolite of the substance 1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium 1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium Not in list C8H9N2O O=C1NCC[n+]2ccccc12 InChI=1/C8H8N2O/c11-8-7-3-1-2-5-10(7)6-4-9-8/h1-3,5H,4,6H2/p+1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: The United Kingdom Diquat 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diquat 27Nov2015 2015 doi:10.2903/j.efsa.2015.4308
+Diquat 220-433-0 85-00-7 single chemical entity Component is a metabolite of the substance 1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium 1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium Not in list C8H9N2O O=C1NCC[n+]2ccccc12 InChI=1/C8H8N2O/c11-8-7-3-1-2-5-10(7)6-4-9-8/h1-3,5H,4,6H2/p+1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: The United Kingdom Diquat 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diquat 27Nov2015 2015 doi:10.2903/j.efsa.2015.4308
+Diquat 220-433-0 85-00-7 single chemical entity Component is a metabolite of the substance 1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium 1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium Not in list C8H9N2O O=C1NCC[n+]2ccccc12 InChI=1/C8H8N2O/c11-8-7-3-1-2-5-10(7)6-4-9-8/h1-3,5H,4,6H2/p+1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: The United Kingdom Diquat 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diquat 27Nov2015 2015 doi:10.2903/j.efsa.2015.4308
+Diquat 220-433-0 85-00-7 single chemical entity Component is a metabolite of the substance 1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium 1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium Not in list C8H9N2O O=C1NCC[n+]2ccccc12 InChI=1/C8H8N2O/c11-8-7-3-1-2-5-10(7)6-4-9-8/h1-3,5H,4,6H2/p+1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: The United Kingdom Diquat 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diquat 27Nov2015 2015 doi:10.2903/j.efsa.2015.4308
+Diquat 220-433-0 85-00-7 single chemical entity Component is a metabolite of the substance 1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium 1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium Not in list C8H9N2O O=C1NCC[n+]2ccccc12 InChI=1/C8H8N2O/c11-8-7-3-1-2-5-10(7)6-4-9-8/h1-3,5H,4,6H2/p+1 organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported no data without Negative RMS: The United Kingdom Diquat 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diquat 27Nov2015 2015 doi:10.2903/j.efsa.2015.4308
+Diquat 220-433-0 85-00-7 single chemical entity Component is a metabolite of the substance 1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium 1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium Not in list C8H9N2O O=C1NCC[n+]2ccccc12 InChI=1/C8H8N2O/c11-8-7-3-1-2-5-10(7)6-4-9-8/h1-3,5H,4,6H2/p+1 organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported no data with Negative RMS: The United Kingdom Diquat 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diquat 27Nov2015 2015 doi:10.2903/j.efsa.2015.4308
+Diquat 220-433-0 85-00-7 single chemical entity Component is a metabolite of the substance 1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium 1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium Not in list C8H9N2O O=C1NCC[n+]2ccccc12 InChI=1/C8H8N2O/c11-8-7-3-1-2-5-10(7)6-4-9-8/h1-3,5H,4,6H2/p+1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: The United Kingdom Diquat 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diquat 27Nov2015 2015 doi:10.2903/j.efsa.2015.4308
+Dodemorph acetate 250-778-2 31717-87-0 single chemical entity Component is identical to the substance Dodemorph acetate 250-778-2 31717-87-0 Acetic acid;4-cyclododecyl-2,6-dimethylmorpholine Not in list C20H39NO3 CC1CN(CC(O1)C)C2CCCCCCCCCCC2.CC(=O)O InChI=1S/C18H35NO.C2H4O2/c1-16-14-19(15-17(2)20-16)18-12-10-8-6-4-3-5-7-9-11-13-18;1-2(3)4/h16-18H,3-15H2,1-2H3;1H3,(H,3,4) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Dodemorph 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dodemorph (considered variant dodemorph acetate) 17Oct2008 2008 doi:10.2903/j.efsa.2008.170r
+Dodemorph acetate 250-778-2 31717-87-0 single chemical entity Component is identical to the substance Dodemorph acetate 250-778-2 31717-87-0 Acetic acid;4-cyclododecyl-2,6-dimethylmorpholine Not in list C20H39NO3 CC1CN(CC(O1)C)C2CCCCCCCCCCC2.CC(=O)O InChI=1S/C18H35NO.C2H4O2/c1-16-14-19(15-17(2)20-16)18-12-10-8-6-4-3-5-7-9-11-13-18;1-2(3)4/h16-18H,3-15H2,1-2H3;1H3,(H,3,4) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Dodemorph 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dodemorph (considered variant dodemorph acetate) 17Oct2008 2008 doi:10.2903/j.efsa.2008.170r
+Dodemorph acetate 250-778-2 31717-87-0 single chemical entity Component is identical to the substance Dodemorph acetate 250-778-2 31717-87-0 Acetic acid;4-cyclododecyl-2,6-dimethylmorpholine Not in list C20H39NO3 CC1CN(CC(O1)C)C2CCCCCCCCCCC2.CC(=O)O InChI=1S/C18H35NO.C2H4O2/c1-16-14-19(15-17(2)20-16)18-12-10-8-6-4-3-5-7-9-11-13-18;1-2(3)4/h16-18H,3-15H2,1-2H3;1H3,(H,3,4) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Dodemorph 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dodemorph (considered variant dodemorph acetate) 17Oct2008 2008 doi:10.2903/j.efsa.2008.170r
+Dodemorph acetate 250-778-2 31717-87-0 single chemical entity Component is identical to the substance Dodemorph acetate 250-778-2 31717-87-0 Acetic acid;4-cyclododecyl-2,6-dimethylmorpholine Not in list C20H39NO3 CC1CN(CC(O1)C)C2CCCCCCCCCCC2.CC(=O)O InChI=1S/C18H35NO.C2H4O2/c1-16-14-19(15-17(2)20-16)18-12-10-8-6-4-3-5-7-9-11-13-18;1-2(3)4/h16-18H,3-15H2,1-2H3;1H3,(H,3,4) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Dodemorph 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dodemorph (considered variant dodemorph acetate) 17Oct2008 2008 doi:10.2903/j.efsa.2008.170r
+Dodemorph acetate 250-778-2 31717-87-0 single chemical entity Component is identical to the substance Dodemorph acetate 250-778-2 31717-87-0 Acetic acid;4-cyclododecyl-2,6-dimethylmorpholine Not in list C20H39NO3 CC1CN(CC(O1)C)C2CCCCCCCCCCC2.CC(=O)O InChI=1S/C18H35NO.C2H4O2/c1-16-14-19(15-17(2)20-16)18-12-10-8-6-4-3-5-7-9-11-13-18;1-2(3)4/h16-18H,3-15H2,1-2H3;1H3,(H,3,4) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Dodemorph 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dodemorph (considered variant dodemorph acetate) 17Oct2008 2008 doi:10.2903/j.efsa.2008.170r
+Dodemorph acetate 250-778-2 31717-87-0 single chemical entity Component is identical to the substance Dodemorph acetate 250-778-2 31717-87-0 Acetic acid;4-cyclododecyl-2,6-dimethylmorpholine Not in list C20H39NO3 CC1CN(CC(O1)C)C2CCCCCCCCCCC2.CC(=O)O InChI=1S/C18H35NO.C2H4O2/c1-16-14-19(15-17(2)20-16)18-12-10-8-6-4-3-5-7-9-11-13-18;1-2(3)4/h16-18H,3-15H2,1-2H3;1H3,(H,3,4) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Dodemorph 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dodemorph (considered variant dodemorph acetate) 17Oct2008 2008 doi:10.2903/j.efsa.2008.170r
+Dodemorph acetate 250-778-2 31717-87-0 single chemical entity Component is identical to the substance Dodemorph acetate 250-778-2 31717-87-0 Acetic acid;4-cyclododecyl-2,6-dimethylmorpholine Not in list C20H39NO3 CC1CN(CC(O1)C)C2CCCCCCCCCCC2.CC(=O)O InChI=1S/C18H35NO.C2H4O2/c1-16-14-19(15-17(2)20-16)18-12-10-8-6-4-3-5-7-9-11-13-18;1-2(3)4/h16-18H,3-15H2,1-2H3;1H3,(H,3,4) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Dodemorph 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dodemorph (considered variant dodemorph acetate) 17Oct2008 2008 doi:10.2903/j.efsa.2008.170r
+Dodemorph acetate 250-778-2 31717-87-0 single chemical entity Component is identical to the substance Dodemorph acetate 250-778-2 31717-87-0 Acetic acid;4-cyclododecyl-2,6-dimethylmorpholine Not in list C20H39NO3 CC1CN(CC(O1)C)C2CCCCCCCCCCC2.CC(=O)O InChI=1S/C18H35NO.C2H4O2/c1-16-14-19(15-17(2)20-16)18-12-10-8-6-4-3-5-7-9-11-13-18;1-2(3)4/h16-18H,3-15H2,1-2H3;1H3,(H,3,4) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Dodemorph 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dodemorph (considered variant dodemorph acetate) 17Oct2008 2008 doi:10.2903/j.efsa.2008.170r
+Dodemorph acetate 250-778-2 31717-87-0 single chemical entity Component is identical to the substance Dodemorph acetate 250-778-2 31717-87-0 Acetic acid;4-cyclododecyl-2,6-dimethylmorpholine Not in list C20H39NO3 CC1CN(CC(O1)C)C2CCCCCCCCCCC2.CC(=O)O InChI=1S/C18H35NO.C2H4O2/c1-16-14-19(15-17(2)20-16)18-12-10-8-6-4-3-5-7-9-11-13-18;1-2(3)4/h16-18H,3-15H2,1-2H3;1H3,(H,3,4) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Dodemorph 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dodemorph (considered variant dodemorph acetate) 17Oct2008 2008 doi:10.2903/j.efsa.2008.170r
+Dodemorph acetate 250-778-2 31717-87-0 single chemical entity Component is identical to the substance Dodemorph acetate 250-778-2 31717-87-0 Acetic acid;4-cyclododecyl-2,6-dimethylmorpholine Not in list C20H39NO3 CC1CN(CC(O1)C)C2CCCCCCCCCCC2.CC(=O)O InChI=1S/C18H35NO.C2H4O2/c1-16-14-19(15-17(2)20-16)18-12-10-8-6-4-3-5-7-9-11-13-18;1-2(3)4/h16-18H,3-15H2,1-2H3;1H3,(H,3,4) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Dodemorph 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dodemorph (considered variant dodemorph acetate) 17Oct2008 2008 doi:10.2903/j.efsa.2008.170r
+Dodemorph acetate 250-778-2 31717-87-0 single chemical entity Component is identical to the substance Dodemorph acetate 250-778-2 31717-87-0 Acetic acid;4-cyclododecyl-2,6-dimethylmorpholine Not in list C20H39NO3 CC1CN(CC(O1)C)C2CCCCCCCCCCC2.CC(=O)O InChI=1S/C18H35NO.C2H4O2/c1-16-14-19(15-17(2)20-16)18-12-10-8-6-4-3-5-7-9-11-13-18;1-2(3)4/h16-18H,3-15H2,1-2H3;1H3,(H,3,4) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Dodemorph 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dodemorph (considered variant dodemorph acetate) 17Oct2008 2008 doi:10.2903/j.efsa.2008.170r
+Dodemorph acetate 250-778-2 31717-87-0 single chemical entity Component is identical to the substance Dodemorph acetate 250-778-2 31717-87-0 Acetic acid;4-cyclododecyl-2,6-dimethylmorpholine Not in list C20H39NO3 CC1CN(CC(O1)C)C2CCCCCCCCCCC2.CC(=O)O InChI=1S/C18H35NO.C2H4O2/c1-16-14-19(15-17(2)20-16)18-12-10-8-6-4-3-5-7-9-11-13-18;1-2(3)4/h16-18H,3-15H2,1-2H3;1H3,(H,3,4) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Dodemorph 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dodemorph (considered variant dodemorph acetate) 17Oct2008 2008 doi:10.2903/j.efsa.2008.170r
+Dodemorph acetate 250-778-2 31717-87-0 single chemical entity Component is identical to the substance Dodemorph acetate 250-778-2 31717-87-0 Acetic acid;4-cyclododecyl-2,6-dimethylmorpholine Not in list C20H39NO3 CC1CN(CC(O1)C)C2CCCCCCCCCCC2.CC(=O)O InChI=1S/C18H35NO.C2H4O2/c1-16-14-19(15-17(2)20-16)18-12-10-8-6-4-3-5-7-9-11-13-18;1-2(3)4/h16-18H,3-15H2,1-2H3;1H3,(H,3,4) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Dodemorph 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dodemorph (considered variant dodemorph acetate) 17Oct2008 2008 doi:10.2903/j.efsa.2008.170r
+Dodemorph acetate 250-778-2 31717-87-0 single chemical entity Component is identical to the substance Dodemorph acetate 250-778-2 31717-87-0 Acetic acid;4-cyclododecyl-2,6-dimethylmorpholine Not in list C20H39NO3 CC1CN(CC(O1)C)C2CCCCCCCCCCC2.CC(=O)O InChI=1S/C18H35NO.C2H4O2/c1-16-14-19(15-17(2)20-16)18-12-10-8-6-4-3-5-7-9-11-13-18;1-2(3)4/h16-18H,3-15H2,1-2H3;1H3,(H,3,4) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 10 Male/Female oral: unspecified 16.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: The Netherlands Dodemorph 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dodemorph (considered variant dodemorph acetate) 17Oct2008 2008 doi:10.2903/j.efsa.2008.170r
+Dodemorph acetate 250-778-2 31717-87-0 single chemical entity Component is identical to the substance Dodemorph acetate 250-778-2 31717-87-0 Acetic acid;4-cyclododecyl-2,6-dimethylmorpholine Not in list C20H39NO3 CC1CN(CC(O1)C)C2CCCCCCCCCCC2.CC(=O)O InChI=1S/C18H35NO.C2H4O2/c1-16-14-19(15-17(2)20-16)18-12-10-8-6-4-3-5-7-9-11-13-18;1-2(3)4/h16-18H,3-15H2,1-2H3;1H3,(H,3,4) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 10 Male/Female oral: unspecified 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: The Netherlands Dodemorph 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dodemorph (considered variant dodemorph acetate) 17Oct2008 2008 doi:10.2903/j.efsa.2008.170r
+Dodemorph acetate 250-778-2 31717-87-0 single chemical entity Component is identical to the substance Dodemorph acetate 250-778-2 31717-87-0 Acetic acid;4-cyclododecyl-2,6-dimethylmorpholine Not in list C20H39NO3 CC1CN(CC(O1)C)C2CCCCCCCCCCC2.CC(=O)O InChI=1S/C18H35NO.C2H4O2/c1-16-14-19(15-17(2)20-16)18-12-10-8-6-4-3-5-7-9-11-13-18;1-2(3)4/h16-18H,3-15H2,1-2H3;1H3,(H,3,4) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 10 Male/Female oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: The Netherlands Dodemorph 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dodemorph (considered variant dodemorph acetate) 17Oct2008 2008 doi:10.2903/j.efsa.2008.170r
+Dodine 219-459-5 2439-10-3 single chemical entity Component is identical to the substance Dodine 219-459-5 2439-10-3 1-dodecylguanidine acetate Dodine C13H29N3.C2H4O2 CCCCCCCCCCCCNC(=N)N.CC(=O)O InChI=1/C13H29N3.C2H4O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-13(14)15;1-2(3)4/h2-12H2,1H3,(H4,14,15,16);1H3,(H,3,4) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Portugal Dodine (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dodine 21Jun2010 2010 doi:10.2903/j.efsa.2010.1631
+Dodine 219-459-5 2439-10-3 single chemical entity Component is identical to the substance Dodine 219-459-5 2439-10-3 1-dodecylguanidine acetate Dodine C13H29N3.C2H4O2 CCCCCCCCCCCCNC(=N)N.CC(=O)O InChI=1/C13H29N3.C2H4O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-13(14)15;1-2(3)4/h2-12H2,1H3,(H4,14,15,16);1H3,(H,3,4) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Portugal Dodine (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dodine 21Jun2010 2010 doi:10.2903/j.efsa.2010.1631
+Dodine 219-459-5 2439-10-3 single chemical entity Component is identical to the substance Dodine 219-459-5 2439-10-3 1-dodecylguanidine acetate Dodine C13H29N3.C2H4O2 CCCCCCCCCCCCNC(=N)N.CC(=O)O InChI=1/C13H29N3.C2H4O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-13(14)15;1-2(3)4/h2-12H2,1H3,(H4,14,15,16);1H3,(H,3,4) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Portugal Dodine (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dodine 21Jun2010 2010 doi:10.2903/j.efsa.2010.1631
+Dodine 219-459-5 2439-10-3 single chemical entity Component is identical to the substance Dodine 219-459-5 2439-10-3 1-dodecylguanidine acetate Dodine C13H29N3.C2H4O2 CCCCCCCCCCCCNC(=N)N.CC(=O)O InChI=1/C13H29N3.C2H4O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-13(14)15;1-2(3)4/h2-12H2,1H3,(H4,14,15,16);1H3,(H,3,4) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Portugal Dodine (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dodine 21Jun2010 2010 doi:10.2903/j.efsa.2010.1631
+Dodine 219-459-5 2439-10-3 single chemical entity Component is identical to the substance Dodine 219-459-5 2439-10-3 1-dodecylguanidine acetate Dodine C13H29N3.C2H4O2 CCCCCCCCCCCCNC(=N)N.CC(=O)O InChI=1/C13H29N3.C2H4O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-13(14)15;1-2(3)4/h2-12H2,1H3,(H4,14,15,16);1H3,(H,3,4) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Portugal Dodine (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dodine 21Jun2010 2010 doi:10.2903/j.efsa.2010.1631
+Dodine 219-459-5 2439-10-3 single chemical entity Component is identical to the substance Dodine 219-459-5 2439-10-3 1-dodecylguanidine acetate Dodine C13H29N3.C2H4O2 CCCCCCCCCCCCNC(=N)N.CC(=O)O InChI=1/C13H29N3.C2H4O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-13(14)15;1-2(3)4/h2-12H2,1H3,(H4,14,15,16);1H3,(H,3,4) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Portugal Dodine (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dodine 21Jun2010 2010 doi:10.2903/j.efsa.2010.1631
+Dodine 219-459-5 2439-10-3 single chemical entity Component is identical to the substance Dodine 219-459-5 2439-10-3 1-dodecylguanidine acetate Dodine C13H29N3.C2H4O2 CCCCCCCCCCCCNC(=N)N.CC(=O)O InChI=1/C13H29N3.C2H4O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-13(14)15;1-2(3)4/h2-12H2,1H3,(H4,14,15,16);1H3,(H,3,4) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Portugal Dodine (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dodine 21Jun2010 2010 doi:10.2903/j.efsa.2010.1631
+Dodine 219-459-5 2439-10-3 single chemical entity Component is identical to the substance Dodine 219-459-5 2439-10-3 1-dodecylguanidine acetate Dodine C13H29N3.C2H4O2 CCCCCCCCCCCCNC(=N)N.CC(=O)O InChI=1/C13H29N3.C2H4O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-13(14)15;1-2(3)4/h2-12H2,1H3,(H4,14,15,16);1H3,(H,3,4) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Portugal Dodine (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dodine 21Jun2010 2010 doi:10.2903/j.efsa.2010.1631
+Dodine 219-459-5 2439-10-3 single chemical entity Component is identical to the substance Dodine 219-459-5 2439-10-3 1-dodecylguanidine acetate Dodine C13H29N3.C2H4O2 CCCCCCCCCCCCNC(=N)N.CC(=O)O InChI=1/C13H29N3.C2H4O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-13(14)15;1-2(3)4/h2-12H2,1H3,(H4,14,15,16);1H3,(H,3,4) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Portugal Dodine (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dodine 21Jun2010 2010 doi:10.2903/j.efsa.2010.1631
+Dodine 219-459-5 2439-10-3 single chemical entity Component is identical to the substance Dodine 219-459-5 2439-10-3 1-dodecylguanidine acetate Dodine C13H29N3.C2H4O2 CCCCCCCCCCCCNC(=N)N.CC(=O)O InChI=1/C13H29N3.C2H4O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-13(14)15;1-2(3)4/h2-12H2,1H3,(H4,14,15,16);1H3,(H,3,4) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Portugal Dodine (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dodine 21Jun2010 2010 doi:10.2903/j.efsa.2010.1631
+Dodine 219-459-5 2439-10-3 single chemical entity Component is identical to the substance Dodine 219-459-5 2439-10-3 1-dodecylguanidine acetate Dodine C13H29N3.C2H4O2 CCCCCCCCCCCCNC(=N)N.CC(=O)O InChI=1/C13H29N3.C2H4O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-13(14)15;1-2(3)4/h2-12H2,1H3,(H4,14,15,16);1H3,(H,3,4) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Portugal Dodine (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dodine 21Jun2010 2010 doi:10.2903/j.efsa.2010.1631
+Dodine 219-459-5 2439-10-3 single chemical entity Component is identical to the substance Dodine 219-459-5 2439-10-3 1-dodecylguanidine acetate Dodine C13H29N3.C2H4O2 CCCCCCCCCCCCNC(=N)N.CC(=O)O InChI=1/C13H29N3.C2H4O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-13(14)15;1-2(3)4/h2-12H2,1H3,(H4,14,15,16);1H3,(H,3,4) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Portugal Dodine (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dodine 21Jun2010 2010 doi:10.2903/j.efsa.2010.1631
+Dodine 219-459-5 2439-10-3 single chemical entity Component is identical to the substance Dodine 219-459-5 2439-10-3 1-dodecylguanidine acetate Dodine C13H29N3.C2H4O2 CCCCCCCCCCCCNC(=N)N.CC(=O)O InChI=1/C13H29N3.C2H4O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-13(14)15;1-2(3)4/h2-12H2,1H3,(H4,14,15,16);1H3,(H,3,4) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Portugal Dodine (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dodine 21Jun2010 2010 doi:10.2903/j.efsa.2010.1631
+Dodine 219-459-5 2439-10-3 single chemical entity Component is identical to the substance Dodine 219-459-5 2439-10-3 1-dodecylguanidine acetate Dodine C13H29N3.C2H4O2 CCCCCCCCCCCCNC(=N)N.CC(=O)O InChI=1/C13H29N3.C2H4O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-13(14)15;1-2(3)4/h2-12H2,1H3,(H4,14,15,16);1H3,(H,3,4) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Portugal Dodine (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dodine 21Jun2010 2010 doi:10.2903/j.efsa.2010.1631
+Dodine 219-459-5 2439-10-3 single chemical entity Component is identical to the substance Dodine 219-459-5 2439-10-3 1-dodecylguanidine acetate Dodine C13H29N3.C2H4O2 CCCCCCCCCCCCNC(=N)N.CC(=O)O InChI=1/C13H29N3.C2H4O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-13(14)15;1-2(3)4/h2-12H2,1H3,(H4,14,15,16);1H3,(H,3,4) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: Portugal Dodine (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dodine 21Jun2010 2010 doi:10.2903/j.efsa.2010.1631
+Dodine 219-459-5 2439-10-3 single chemical entity Component is identical to the substance Dodine 219-459-5 2439-10-3 1-dodecylguanidine acetate Dodine C13H29N3.C2H4O2 CCCCCCCCCCCCNC(=N)N.CC(=O)O InChI=1/C13H29N3.C2H4O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-13(14)15;1-2(3)4/h2-12H2,1H3,(H4,14,15,16);1H3,(H,3,4) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: Portugal Dodine (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dodine 21Jun2010 2010 doi:10.2903/j.efsa.2010.1631
+Dodine 219-459-5 2439-10-3 single chemical entity Component is identical to the substance Dodine 219-459-5 2439-10-3 1-dodecylguanidine acetate Dodine C13H29N3.C2H4O2 CCCCCCCCCCCCNC(=N)N.CC(=O)O InChI=1/C13H29N3.C2H4O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-13(14)15;1-2(3)4/h2-12H2,1H3,(H4,14,15,16);1H3,(H,3,4) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Swiss 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Portugal Dodine (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dodine 21Jun2010 2010 doi:10.2903/j.efsa.2010.1631
+Dodine 219-459-5 2439-10-3 single chemical entity Component is identical to the substance Dodine 219-459-5 2439-10-3 1-dodecylguanidine acetate Dodine C13H29N3.C2H4O2 CCCCCCCCCCCCNC(=N)N.CC(=O)O InChI=1/C13H29N3.C2H4O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-13(14)15;1-2(3)4/h2-12H2,1H3,(H4,14,15,16);1H3,(H,3,4) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Swiss 10 Male/Female oral: gavage 72.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Portugal Dodine (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dodine 21Jun2010 2010 doi:10.2903/j.efsa.2010.1631
+Dodine 219-459-5 2439-10-3 single chemical entity Component is identical to the substance Dodine 219-459-5 2439-10-3 1-dodecylguanidine acetate Dodine C13H29N3.C2H4O2 CCCCCCCCCCCCNC(=N)N.CC(=O)O InChI=1/C13H29N3.C2H4O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-13(14)15;1-2(3)4/h2-12H2,1H3,(H4,14,15,16);1H3,(H,3,4) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Swiss 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Portugal Dodine (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dodine 21Jun2010 2010 doi:10.2903/j.efsa.2010.1631
+Dodine 219-459-5 2439-10-3 single chemical entity Component is identical to the substance Dodine 219-459-5 2439-10-3 1-dodecylguanidine acetate Dodine C13H29N3.C2H4O2 CCCCCCCCCCCCNC(=N)N.CC(=O)O InChI=1/C13H29N3.C2H4O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-13(14)15;1-2(3)4/h2-12H2,1H3,(H4,14,15,16);1H3,(H,3,4) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) ICR 10 Male/Female oral: gavage 72.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Portugal Dodine (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dodine 21Jun2010 2010 doi:10.2903/j.efsa.2010.1631
+Dodine 219-459-5 2439-10-3 single chemical entity Component is identical to the substance Dodine 219-459-5 2439-10-3 1-dodecylguanidine acetate Dodine C13H29N3.C2H4O2 CCCCCCCCCCCCNC(=N)N.CC(=O)O InChI=1/C13H29N3.C2H4O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-13(14)15;1-2(3)4/h2-12H2,1H3,(H4,14,15,16);1H3,(H,3,4) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) ICR 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Portugal Dodine (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dodine 21Jun2010 2010 doi:10.2903/j.efsa.2010.1631
+Dodine 219-459-5 2439-10-3 single chemical entity Component is identical to the substance Dodine 219-459-5 2439-10-3 1-dodecylguanidine acetate Dodine C13H29N3.C2H4O2 CCCCCCCCCCCCNC(=N)N.CC(=O)O InChI=1/C13H29N3.C2H4O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-13(14)15;1-2(3)4/h2-12H2,1H3,(H4,14,15,16);1H3,(H,3,4) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) ICR 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Portugal Dodine (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dodine 21Jun2010 2010 doi:10.2903/j.efsa.2010.1631
+Dodine 219-459-5 2439-10-3 single chemical entity Component is identical to the substance Dodine 219-459-5 2439-10-3 1-dodecylguanidine acetate Dodine C13H29N3.C2H4O2 CCCCCCCCCCCCNC(=N)N.CC(=O)O InChI=1/C13H29N3.C2H4O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-13(14)15;1-2(3)4/h2-12H2,1H3,(H4,14,15,16);1H3,(H,3,4) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Portugal Dodine (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dodine 21Jun2010 2010 doi:10.2903/j.efsa.2010.1631
+Dodine 219-459-5 2439-10-3 single chemical entity Component is identical to the substance Dodine 219-459-5 2439-10-3 1-dodecylguanidine acetate Dodine C13H29N3.C2H4O2 CCCCCCCCCCCCNC(=N)N.CC(=O)O InChI=1/C13H29N3.C2H4O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-13(14)15;1-2(3)4/h2-12H2,1H3,(H4,14,15,16);1H3,(H,3,4) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Portugal Dodine (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dodine 21Jun2010 2010 doi:10.2903/j.efsa.2010.1631
+Dodine 219-459-5 2439-10-3 single chemical entity Component is identical to the substance Dodine 219-459-5 2439-10-3 1-dodecylguanidine acetate Dodine C13H29N3.C2H4O2 CCCCCCCCCCCCNC(=N)N.CC(=O)O InChI=1/C13H29N3.C2H4O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-13(14)15;1-2(3)4/h2-12H2,1H3,(H4,14,15,16);1H3,(H,3,4) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Portugal Dodine (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dodine 21Jun2010 2010 doi:10.2903/j.efsa.2010.1631
+Dodine 219-459-5 2439-10-3 single chemical entity Component is identical to the substance Dodine 219-459-5 2439-10-3 1-dodecylguanidine acetate Dodine C13H29N3.C2H4O2 CCCCCCCCCCCCNC(=N)N.CC(=O)O InChI=1/C13H29N3.C2H4O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-13(14)15;1-2(3)4/h2-12H2,1H3,(H4,14,15,16);1H3,(H,3,4) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Portugal Dodine (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dodine 21Jun2010 2010 doi:10.2903/j.efsa.2010.1631
+Dodine 219-459-5 2439-10-3 single chemical entity Component is identical to the substance Dodine 219-459-5 2439-10-3 1-dodecylguanidine acetate Dodine C13H29N3.C2H4O2 CCCCCCCCCCCCNC(=N)N.CC(=O)O InChI=1/C13H29N3.C2H4O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-13(14)15;1-2(3)4/h2-12H2,1H3,(H4,14,15,16);1H3,(H,3,4) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Portugal Dodine (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dodine 21Jun2010 2010 doi:10.2903/j.efsa.2010.1631
+Dodine 219-459-5 2439-10-3 single chemical entity Component is identical to the substance Dodine 219-459-5 2439-10-3 1-dodecylguanidine acetate Dodine C13H29N3.C2H4O2 CCCCCCCCCCCCNC(=N)N.CC(=O)O InChI=1/C13H29N3.C2H4O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-13(14)15;1-2(3)4/h2-12H2,1H3,(H4,14,15,16);1H3,(H,3,4) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Portugal Dodine (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dodine 21Jun2010 2010 doi:10.2903/j.efsa.2010.1631
+Dodine 219-459-5 2439-10-3 single chemical entity Component is identical to the substance Dodine 219-459-5 2439-10-3 1-dodecylguanidine acetate Dodine C13H29N3.C2H4O2 CCCCCCCCCCCCNC(=N)N.CC(=O)O InChI=1/C13H29N3.C2H4O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-13(14)15;1-2(3)4/h2-12H2,1H3,(H4,14,15,16);1H3,(H,3,4) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Portugal Dodine (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dodine 21Jun2010 2010 doi:10.2903/j.efsa.2010.1631
+Dodine 219-459-5 2439-10-3 single chemical entity Component is identical to the substance Dodine 219-459-5 2439-10-3 1-dodecylguanidine acetate Dodine C13H29N3.C2H4O2 CCCCCCCCCCCCNC(=N)N.CC(=O)O InChI=1/C13H29N3.C2H4O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-13(14)15;1-2(3)4/h2-12H2,1H3,(H4,14,15,16);1H3,(H,3,4) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Portugal Dodine (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dodine 21Jun2010 2010 doi:10.2903/j.efsa.2010.1631
+Epoxiconazole 106325-08-0 single chemical entity Component is identical to the substance Epoxiconazole 106325-08-0 1-{[3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole Epoxiconazole C17H13ClFN3O ClC3=C(C=CC=C3)C1OC(C4=CC=C(F)C=C4)1CN2N=CN=C2 InChI=1S/C17H13ClFN3O/c18-15-4-2-1-3-14(15)16-17(23-16,9-22-11-20-10-21-22)12-5-7-13(19)8-6-12/h1-8,10-11,16H,9H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany Epoxiconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance epoxiconazole 28Jul2008 2008 doi:10.2903/j.efsa.2008.138r
+Epoxiconazole 106325-08-0 single chemical entity Component is identical to the substance Epoxiconazole 106325-08-0 1-{[3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole Epoxiconazole C17H13ClFN3O ClC3=C(C=CC=C3)C1OC(C4=CC=C(F)C=C4)1CN2N=CN=C2 InChI=1S/C17H13ClFN3O/c18-15-4-2-1-3-14(15)16-17(23-16,9-22-11-20-10-21-22)12-5-7-13(19)8-6-12/h1-8,10-11,16H,9H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany Epoxiconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance epoxiconazole 28Jul2008 2008 doi:10.2903/j.efsa.2008.138r
+Epoxiconazole 106325-08-0 single chemical entity Component is identical to the substance Epoxiconazole 106325-08-0 1-{[3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole Epoxiconazole C17H13ClFN3O ClC3=C(C=CC=C3)C1OC(C4=CC=C(F)C=C4)1CN2N=CN=C2 InChI=1S/C17H13ClFN3O/c18-15-4-2-1-3-14(15)16-17(23-16,9-22-11-20-10-21-22)12-5-7-13(19)8-6-12/h1-8,10-11,16H,9H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany Epoxiconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance epoxiconazole 28Jul2008 2008 doi:10.2903/j.efsa.2008.138r
+Epoxiconazole 106325-08-0 single chemical entity Component is identical to the substance Epoxiconazole 106325-08-0 1-{[3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole Epoxiconazole C17H13ClFN3O ClC3=C(C=CC=C3)C1OC(C4=CC=C(F)C=C4)1CN2N=CN=C2 InChI=1S/C17H13ClFN3O/c18-15-4-2-1-3-14(15)16-17(23-16,9-22-11-20-10-21-22)12-5-7-13(19)8-6-12/h1-8,10-11,16H,9H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany Epoxiconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance epoxiconazole 28Jul2008 2008 doi:10.2903/j.efsa.2008.138r
+Epoxiconazole 106325-08-0 single chemical entity Component is identical to the substance Epoxiconazole 106325-08-0 1-{[3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole Epoxiconazole C17H13ClFN3O ClC3=C(C=CC=C3)C1OC(C4=CC=C(F)C=C4)1CN2N=CN=C2 InChI=1S/C17H13ClFN3O/c18-15-4-2-1-3-14(15)16-17(23-16,9-22-11-20-10-21-22)12-5-7-13(19)8-6-12/h1-8,10-11,16H,9H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany Epoxiconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance epoxiconazole 28Jul2008 2008 doi:10.2903/j.efsa.2008.138r
+Epoxiconazole 106325-08-0 single chemical entity Component is identical to the substance Epoxiconazole 106325-08-0 1-{[3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole Epoxiconazole C17H13ClFN3O ClC3=C(C=CC=C3)C1OC(C4=CC=C(F)C=C4)1CN2N=CN=C2 InChI=1S/C17H13ClFN3O/c18-15-4-2-1-3-14(15)16-17(23-16,9-22-11-20-10-21-22)12-5-7-13(19)8-6-12/h1-8,10-11,16H,9H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany Epoxiconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance epoxiconazole 28Jul2008 2008 doi:10.2903/j.efsa.2008.138r
+Epoxiconazole 106325-08-0 single chemical entity Component is identical to the substance Epoxiconazole 106325-08-0 1-{[3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole Epoxiconazole C17H13ClFN3O ClC3=C(C=CC=C3)C1OC(C4=CC=C(F)C=C4)1CN2N=CN=C2 InChI=1S/C17H13ClFN3O/c18-15-4-2-1-3-14(15)16-17(23-16,9-22-11-20-10-21-22)12-5-7-13(19)8-6-12/h1-8,10-11,16H,9H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany Epoxiconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance epoxiconazole 28Jul2008 2008 doi:10.2903/j.efsa.2008.138r
+Epoxiconazole 106325-08-0 single chemical entity Component is identical to the substance Epoxiconazole 106325-08-0 1-{[3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole Epoxiconazole C17H13ClFN3O ClC3=C(C=CC=C3)C1OC(C4=CC=C(F)C=C4)1CN2N=CN=C2 InChI=1S/C17H13ClFN3O/c18-15-4-2-1-3-14(15)16-17(23-16,9-22-11-20-10-21-22)12-5-7-13(19)8-6-12/h1-8,10-11,16H,9H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany Epoxiconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance epoxiconazole 28Jul2008 2008 doi:10.2903/j.efsa.2008.138r
+Epoxiconazole 106325-08-0 single chemical entity Component is identical to the substance Epoxiconazole 106325-08-0 1-{[3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole Epoxiconazole C17H13ClFN3O ClC3=C(C=CC=C3)C1OC(C4=CC=C(F)C=C4)1CN2N=CN=C2 InChI=1S/C17H13ClFN3O/c18-15-4-2-1-3-14(15)16-17(23-16,9-22-11-20-10-21-22)12-5-7-13(19)8-6-12/h1-8,10-11,16H,9H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: Germany Epoxiconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance epoxiconazole 28Jul2008 2008 doi:10.2903/j.efsa.2008.138r
+Epoxiconazole 106325-08-0 single chemical entity Component is identical to the substance Epoxiconazole 106325-08-0 1-{[3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole Epoxiconazole C17H13ClFN3O ClC3=C(C=CC=C3)C1OC(C4=CC=C(F)C=C4)1CN2N=CN=C2 InChI=1S/C17H13ClFN3O/c18-15-4-2-1-3-14(15)16-17(23-16,9-22-11-20-10-21-22)12-5-7-13(19)8-6-12/h1-8,10-11,16H,9H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: Germany Epoxiconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance epoxiconazole 28Jul2008 2008 doi:10.2903/j.efsa.2008.138r
+Epoxiconazole 106325-08-0 single chemical entity Component is identical to the substance Epoxiconazole 106325-08-0 1-{[3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole Epoxiconazole C17H13ClFN3O ClC3=C(C=CC=C3)C1OC(C4=CC=C(F)C=C4)1CN2N=CN=C2 InChI=1S/C17H13ClFN3O/c18-15-4-2-1-3-14(15)16-17(23-16,9-22-11-20-10-21-22)12-5-7-13(19)8-6-12/h1-8,10-11,16H,9H2 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Germany Epoxiconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance epoxiconazole 28Jul2008 2008 doi:10.2903/j.efsa.2008.138r
+Epoxiconazole 106325-08-0 single chemical entity Component is identical to the substance Epoxiconazole 106325-08-0 1-{[3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole Epoxiconazole C17H13ClFN3O ClC3=C(C=CC=C3)C1OC(C4=CC=C(F)C=C4)1CN2N=CN=C2 InChI=1S/C17H13ClFN3O/c18-15-4-2-1-3-14(15)16-17(23-16,9-22-11-20-10-21-22)12-5-7-13(19)8-6-12/h1-8,10-11,16H,9H2 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Germany Epoxiconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance epoxiconazole 28Jul2008 2008 doi:10.2903/j.efsa.2008.138r
+Epoxiconazole 106325-08-0 single chemical entity Component is identical to the substance Epoxiconazole 106325-08-0 1-{[3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole Epoxiconazole C17H13ClFN3O ClC3=C(C=CC=C3)C1OC(C4=CC=C(F)C=C4)1CN2N=CN=C2 InChI=1S/C17H13ClFN3O/c18-15-4-2-1-3-14(15)16-17(23-16,9-22-11-20-10-21-22)12-5-7-13(19)8-6-12/h1-8,10-11,16H,9H2 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Germany Epoxiconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance epoxiconazole 28Jul2008 2008 doi:10.2903/j.efsa.2008.138r
+Epoxiconazole 106325-08-0 single chemical entity Component is identical to the substance Epoxiconazole 106325-08-0 1-{[3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole Epoxiconazole C17H13ClFN3O ClC3=C(C=CC=C3)C1OC(C4=CC=C(F)C=C4)1CN2N=CN=C2 InChI=1S/C17H13ClFN3O/c18-15-4-2-1-3-14(15)16-17(23-16,9-22-11-20-10-21-22)12-5-7-13(19)8-6-12/h1-8,10-11,16H,9H2 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Germany Epoxiconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance epoxiconazole 28Jul2008 2008 doi:10.2903/j.efsa.2008.138r
+Epoxiconazole 106325-08-0 single chemical entity Component is identical to the substance Epoxiconazole 106325-08-0 1-{[3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole Epoxiconazole C17H13ClFN3O ClC3=C(C=CC=C3)C1OC(C4=CC=C(F)C=C4)1CN2N=CN=C2 InChI=1S/C17H13ClFN3O/c18-15-4-2-1-3-14(15)16-17(23-16,9-22-11-20-10-21-22)12-5-7-13(19)8-6-12/h1-8,10-11,16H,9H2 organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Germany Epoxiconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance epoxiconazole 28Jul2008 2008 doi:10.2903/j.efsa.2008.138r
+Epoxiconazole 106325-08-0 single chemical entity Component is identical to the substance Epoxiconazole 106325-08-0 1-{[3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole Epoxiconazole C17H13ClFN3O ClC3=C(C=CC=C3)C1OC(C4=CC=C(F)C=C4)1CN2N=CN=C2 InChI=1S/C17H13ClFN3O/c18-15-4-2-1-3-14(15)16-17(23-16,9-22-11-20-10-21-22)12-5-7-13(19)8-6-12/h1-8,10-11,16H,9H2 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 16.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Germany Epoxiconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance epoxiconazole 28Jul2008 2008 doi:10.2903/j.efsa.2008.138r
+Epoxiconazole 106325-08-0 single chemical entity Component is identical to the substance Epoxiconazole 106325-08-0 1-{[3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole Epoxiconazole C17H13ClFN3O ClC3=C(C=CC=C3)C1OC(C4=CC=C(F)C=C4)1CN2N=CN=C2 InChI=1S/C17H13ClFN3O/c18-15-4-2-1-3-14(15)16-17(23-16,9-22-11-20-10-21-22)12-5-7-13(19)8-6-12/h1-8,10-11,16H,9H2 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Germany Epoxiconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance epoxiconazole 28Jul2008 2008 doi:10.2903/j.efsa.2008.138r
+Epoxiconazole 106325-08-0 single chemical entity Component is identical to the substance Epoxiconazole 106325-08-0 1-{[3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole Epoxiconazole C17H13ClFN3O ClC3=C(C=CC=C3)C1OC(C4=CC=C(F)C=C4)1CN2N=CN=C2 InChI=1S/C17H13ClFN3O/c18-15-4-2-1-3-14(15)16-17(23-16,9-22-11-20-10-21-22)12-5-7-13(19)8-6-12/h1-8,10-11,16H,9H2 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Germany Epoxiconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance epoxiconazole 28Jul2008 2008 doi:10.2903/j.efsa.2008.138r
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is a metabolite of the substance 2,5-dichloro-3-hydroxy-6-methoxybenzoic acid 7600-50-2 2,5-dichloro-3-hydroxy-6-methoxybenzoic acid Not in list C8H6Cl2O4 COC1=C(C=C(C(=C1C(=O)O)Cl)O)Cl InChI=1S/C8H6Cl2O4/c1-14-7-3(9)2-4(11)6(10)5(7)8(12)13/h2,11H,1H3,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is a metabolite of the substance 2,5-dichloro-3-hydroxy-6-methoxybenzoic acid 7600-50-2 2,5-dichloro-3-hydroxy-6-methoxybenzoic acid Not in list C8H6Cl2O4 COC1=C(C=C(C(=C1C(=O)O)Cl)O)Cl InChI=1S/C8H6Cl2O4/c1-14-7-3(9)2-4(11)6(10)5(7)8(12)13/h2,11H,1H3,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is a metabolite of the substance 2,5-dichloro-3-hydroxy-6-methoxybenzoic acid 7600-50-2 2,5-dichloro-3-hydroxy-6-methoxybenzoic acid Not in list C8H6Cl2O4 COC1=C(C=C(C(=C1C(=O)O)Cl)O)Cl InChI=1S/C8H6Cl2O4/c1-14-7-3(9)2-4(11)6(10)5(7)8(12)13/h2,11H,1H3,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is a metabolite of the substance 2,5-dichloro-3-hydroxy-6-methoxybenzoic acid 7600-50-2 2,5-dichloro-3-hydroxy-6-methoxybenzoic acid Not in list C8H6Cl2O4 COC1=C(C=C(C(=C1C(=O)O)Cl)O)Cl InChI=1S/C8H6Cl2O4/c1-14-7-3(9)2-4(11)6(10)5(7)8(12)13/h2,11H,1H3,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is a metabolite of the substance 2,5-dichloro-3-hydroxy-6-methoxybenzoic acid 7600-50-2 2,5-dichloro-3-hydroxy-6-methoxybenzoic acid Not in list C8H6Cl2O4 COC1=C(C=C(C(=C1C(=O)O)Cl)O)Cl InChI=1S/C8H6Cl2O4/c1-14-7-3(9)2-4(11)6(10)5(7)8(12)13/h2,11H,1H3,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is a metabolite of the substance 2,5-dichloro-3-hydroxy-6-methoxybenzoic acid 7600-50-2 2,5-dichloro-3-hydroxy-6-methoxybenzoic acid Not in list C8H6Cl2O4 COC1=C(C=C(C(=C1C(=O)O)Cl)O)Cl InChI=1S/C8H6Cl2O4/c1-14-7-3(9)2-4(11)6(10)5(7)8(12)13/h2,11H,1H3,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is a metabolite of the substance 2,5-dichloro-3-hydroxy-6-methoxybenzoic acid 7600-50-2 2,5-dichloro-3-hydroxy-6-methoxybenzoic acid Not in list C8H6Cl2O4 COC1=C(C=C(C(=C1C(=O)O)Cl)O)Cl InChI=1S/C8H6Cl2O4/c1-14-7-3(9)2-4(11)6(10)5(7)8(12)13/h2,11H,1H3,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is a metabolite of the substance 2,5-dichloro-3-hydroxy-6-methoxybenzoic acid 7600-50-2 2,5-dichloro-3-hydroxy-6-methoxybenzoic acid Not in list C8H6Cl2O4 COC1=C(C=C(C(=C1C(=O)O)Cl)O)Cl InChI=1S/C8H6Cl2O4/c1-14-7-3(9)2-4(11)6(10)5(7)8(12)13/h2,11H,1H3,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is a metabolite of the substance 2,5-dichloro-3-hydroxy-6-methoxybenzoic acid 7600-50-2 2,5-dichloro-3-hydroxy-6-methoxybenzoic acid Not in list C8H6Cl2O4 COC1=C(C=C(C(=C1C(=O)O)Cl)O)Cl InChI=1S/C8H6Cl2O4/c1-14-7-3(9)2-4(11)6(10)5(7)8(12)13/h2,11H,1H3,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is a metabolite of the substance 2,5-dichloro-3-hydroxy-6-methoxybenzoic acid 7600-50-2 2,5-dichloro-3-hydroxy-6-methoxybenzoic acid Not in list C8H6Cl2O4 COC1=C(C=C(C(=C1C(=O)O)Cl)O)Cl InChI=1S/C8H6Cl2O4/c1-14-7-3(9)2-4(11)6(10)5(7)8(12)13/h2,11H,1H3,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is a metabolite of the substance 2,5-dichloro-3-hydroxy-6-methoxybenzoic acid 7600-50-2 2,5-dichloro-3-hydroxy-6-methoxybenzoic acid Not in list C8H6Cl2O4 COC1=C(C=C(C(=C1C(=O)O)Cl)O)Cl InChI=1S/C8H6Cl2O4/c1-14-7-3(9)2-4(11)6(10)5(7)8(12)13/h2,11H,1H3,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is a metabolite of the substance 2,5-dichloro-3-hydroxy-6-methoxybenzoic acid 7600-50-2 2,5-dichloro-3-hydroxy-6-methoxybenzoic acid Not in list C8H6Cl2O4 COC1=C(C=C(C(=C1C(=O)O)Cl)O)Cl InChI=1S/C8H6Cl2O4/c1-14-7-3(9)2-4(11)6(10)5(7)8(12)13/h2,11H,1H3,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is a metabolite of the substance 2,5-dichloro-3-hydroxy-6-methoxybenzoic acid 7600-50-2 2,5-dichloro-3-hydroxy-6-methoxybenzoic acid Not in list C8H6Cl2O4 COC1=C(C=C(C(=C1C(=O)O)Cl)O)Cl InChI=1S/C8H6Cl2O4/c1-14-7-3(9)2-4(11)6(10)5(7)8(12)13/h2,11H,1H3,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Positive no information RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is a metabolite of the substance 2,5-dichloro-3-hydroxy-6-methoxybenzoic acid 7600-50-2 2,5-dichloro-3-hydroxy-6-methoxybenzoic acid Not in list C8H6Cl2O4 COC1=C(C=C(C(=C1C(=O)O)Cl)O)Cl InChI=1S/C8H6Cl2O4/c1-14-7-3(9)2-4(11)6(10)5(7)8(12)13/h2,11H,1H3,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Positive no information RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is a metabolite of the substance 2,5-dichloro-3-hydroxy-6-methoxybenzoic acid 7600-50-2 2,5-dichloro-3-hydroxy-6-methoxybenzoic acid Not in list C8H6Cl2O4 COC1=C(C=C(C(=C1C(=O)O)Cl)O)Cl InChI=1S/C8H6Cl2O4/c1-14-7-3(9)2-4(11)6(10)5(7)8(12)13/h2,11H,1H3,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is a metabolite of the substance 2,5-dichloro-3-hydroxy-6-methoxybenzoic acid 7600-50-2 2,5-dichloro-3-hydroxy-6-methoxybenzoic acid Not in list C8H6Cl2O4 COC1=C(C=C(C(=C1C(=O)O)Cl)O)Cl InChI=1S/C8H6Cl2O4/c1-14-7-3(9)2-4(11)6(10)5(7)8(12)13/h2,11H,1H3,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Positive RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is a metabolite of the substance 2,5-dichloro-3-hydroxy-6-methoxybenzoic acid 7600-50-2 2,5-dichloro-3-hydroxy-6-methoxybenzoic acid Not in list C8H6Cl2O4 COC1=C(C=C(C(=C1C(=O)O)Cl)O)Cl InChI=1S/C8H6Cl2O4/c1-14-7-3(9)2-4(11)6(10)5(7)8(12)13/h2,11H,1H3,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is a metabolite of the substance 2,5-dichloro-3-hydroxy-6-methoxybenzoic acid 7600-50-2 2,5-dichloro-3-hydroxy-6-methoxybenzoic acid Not in list C8H6Cl2O4 COC1=C(C=C(C(=C1C(=O)O)Cl)O)Cl InChI=1S/C8H6Cl2O4/c1-14-7-3(9)2-4(11)6(10)5(7)8(12)13/h2,11H,1H3,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is a metabolite of the substance 2,5-dichloro-3-hydroxy-6-methoxybenzoic acid 7600-50-2 2,5-dichloro-3-hydroxy-6-methoxybenzoic acid Not in list C8H6Cl2O4 COC1=C(C=C(C(=C1C(=O)O)Cl)O)Cl InChI=1S/C8H6Cl2O4/c1-14-7-3(9)2-4(11)6(10)5(7)8(12)13/h2,11H,1H3,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 5 Male oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is a metabolite of the substance 2,5-dichloro-3-hydroxy-6-methoxybenzoic acid 7600-50-2 2,5-dichloro-3-hydroxy-6-methoxybenzoic acid Not in list C8H6Cl2O4 COC1=C(C=C(C(=C1C(=O)O)Cl)O)Cl InChI=1S/C8H6Cl2O4/c1-14-7-3(9)2-4(11)6(10)5(7)8(12)13/h2,11H,1H3,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 5 Male oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Sprague-Dawley 3 Male oral: unspecified 2.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Sprague-Dawley 3 Male oral: unspecified 16.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Esfenvalerate 66230-04-4 single chemical entity Component is identical to the substance Esfenvalerate 66230-04-4 (alphaS)-alpha-cyano-3-phenoxybenzyl(2S)-2-(4-chlorophenyl)-3-methylbutyrate Esfenvalerate C25H22ClNO3 CC(C)C(C1=CC=C(C=C1)Cl)C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C25H22ClNO3/c1-17(2)24(18-11-13-20(26)14-12-18)25(28)30-23(16-27)19-7-6-10-22(15-19)29-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3/t23-,24+/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Esfenvalerate 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate 03Nov2014 2014 doi:10.2903/j.efsa.2014.3873
+Esfenvalerate 66230-04-4 single chemical entity Component is identical to the substance Esfenvalerate 66230-04-4 (alphaS)-alpha-cyano-3-phenoxybenzyl(2S)-2-(4-chlorophenyl)-3-methylbutyrate Esfenvalerate C25H22ClNO3 CC(C)C(C1=CC=C(C=C1)Cl)C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C25H22ClNO3/c1-17(2)24(18-11-13-20(26)14-12-18)25(28)30-23(16-27)19-7-6-10-22(15-19)29-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3/t23-,24+/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Esfenvalerate 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate 03Nov2014 2014 doi:10.2903/j.efsa.2014.3873
+Esfenvalerate 66230-04-4 single chemical entity Component is identical to the substance Esfenvalerate 66230-04-4 (alphaS)-alpha-cyano-3-phenoxybenzyl(2S)-2-(4-chlorophenyl)-3-methylbutyrate Esfenvalerate C25H22ClNO3 CC(C)C(C1=CC=C(C=C1)Cl)C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C25H22ClNO3/c1-17(2)24(18-11-13-20(26)14-12-18)25(28)30-23(16-27)19-7-6-10-22(15-19)29-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3/t23-,24+/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Esfenvalerate 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate 03Nov2014 2014 doi:10.2903/j.efsa.2014.3873
+Esfenvalerate 66230-04-4 single chemical entity Component is identical to the substance Esfenvalerate 66230-04-4 (alphaS)-alpha-cyano-3-phenoxybenzyl(2S)-2-(4-chlorophenyl)-3-methylbutyrate Esfenvalerate C25H22ClNO3 CC(C)C(C1=CC=C(C=C1)Cl)C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C25H22ClNO3/c1-17(2)24(18-11-13-20(26)14-12-18)25(28)30-23(16-27)19-7-6-10-22(15-19)29-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3/t23-,24+/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Esfenvalerate 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate 03Nov2014 2014 doi:10.2903/j.efsa.2014.3873
+Esfenvalerate 66230-04-4 single chemical entity Component is identical to the substance Esfenvalerate 66230-04-4 (alphaS)-alpha-cyano-3-phenoxybenzyl(2S)-2-(4-chlorophenyl)-3-methylbutyrate Esfenvalerate C25H22ClNO3 CC(C)C(C1=CC=C(C=C1)Cl)C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C25H22ClNO3/c1-17(2)24(18-11-13-20(26)14-12-18)25(28)30-23(16-27)19-7-6-10-22(15-19)29-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3/t23-,24+/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Esfenvalerate 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate 03Nov2014 2014 doi:10.2903/j.efsa.2014.3873
+Esfenvalerate 66230-04-4 single chemical entity Component is identical to the substance Esfenvalerate 66230-04-4 (alphaS)-alpha-cyano-3-phenoxybenzyl(2S)-2-(4-chlorophenyl)-3-methylbutyrate Esfenvalerate C25H22ClNO3 CC(C)C(C1=CC=C(C=C1)Cl)C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C25H22ClNO3/c1-17(2)24(18-11-13-20(26)14-12-18)25(28)30-23(16-27)19-7-6-10-22(15-19)29-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3/t23-,24+/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Esfenvalerate 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate 03Nov2014 2014 doi:10.2903/j.efsa.2014.3873
+Esfenvalerate 66230-04-4 single chemical entity Component is identical to the substance Esfenvalerate 66230-04-4 (alphaS)-alpha-cyano-3-phenoxybenzyl(2S)-2-(4-chlorophenyl)-3-methylbutyrate Esfenvalerate C25H22ClNO3 CC(C)C(C1=CC=C(C=C1)Cl)C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C25H22ClNO3/c1-17(2)24(18-11-13-20(26)14-12-18)25(28)30-23(16-27)19-7-6-10-22(15-19)29-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3/t23-,24+/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Esfenvalerate 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate 03Nov2014 2014 doi:10.2903/j.efsa.2014.3873
+Esfenvalerate 66230-04-4 single chemical entity Component is identical to the substance Esfenvalerate 66230-04-4 (alphaS)-alpha-cyano-3-phenoxybenzyl(2S)-2-(4-chlorophenyl)-3-methylbutyrate Esfenvalerate C25H22ClNO3 CC(C)C(C1=CC=C(C=C1)Cl)C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C25H22ClNO3/c1-17(2)24(18-11-13-20(26)14-12-18)25(28)30-23(16-27)19-7-6-10-22(15-19)29-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3/t23-,24+/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Esfenvalerate 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate 03Nov2014 2014 doi:10.2903/j.efsa.2014.3873
+Esfenvalerate 66230-04-4 single chemical entity Component is identical to the substance Esfenvalerate 66230-04-4 (alphaS)-alpha-cyano-3-phenoxybenzyl(2S)-2-(4-chlorophenyl)-3-methylbutyrate Esfenvalerate C25H22ClNO3 CC(C)C(C1=CC=C(C=C1)Cl)C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C25H22ClNO3/c1-17(2)24(18-11-13-20(26)14-12-18)25(28)30-23(16-27)19-7-6-10-22(15-19)29-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3/t23-,24+/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Esfenvalerate 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate 03Nov2014 2014 doi:10.2903/j.efsa.2014.3873
+Esfenvalerate 66230-04-4 single chemical entity Component is identical to the substance Esfenvalerate 66230-04-4 (alphaS)-alpha-cyano-3-phenoxybenzyl(2S)-2-(4-chlorophenyl)-3-methylbutyrate Esfenvalerate C25H22ClNO3 CC(C)C(C1=CC=C(C=C1)Cl)C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C25H22ClNO3/c1-17(2)24(18-11-13-20(26)14-12-18)25(28)30-23(16-27)19-7-6-10-22(15-19)29-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3/t23-,24+/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Esfenvalerate 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate 03Nov2014 2014 doi:10.2903/j.efsa.2014.3873
+Esfenvalerate 66230-04-4 single chemical entity Component is identical to the substance Esfenvalerate 66230-04-4 (alphaS)-alpha-cyano-3-phenoxybenzyl(2S)-2-(4-chlorophenyl)-3-methylbutyrate Esfenvalerate C25H22ClNO3 CC(C)C(C1=CC=C(C=C1)Cl)C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C25H22ClNO3/c1-17(2)24(18-11-13-20(26)14-12-18)25(28)30-23(16-27)19-7-6-10-22(15-19)29-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3/t23-,24+/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Esfenvalerate 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate 03Nov2014 2014 doi:10.2903/j.efsa.2014.3873
+Esfenvalerate 66230-04-4 single chemical entity Component is identical to the substance Esfenvalerate 66230-04-4 (alphaS)-alpha-cyano-3-phenoxybenzyl(2S)-2-(4-chlorophenyl)-3-methylbutyrate Esfenvalerate C25H22ClNO3 CC(C)C(C1=CC=C(C=C1)Cl)C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C25H22ClNO3/c1-17(2)24(18-11-13-20(26)14-12-18)25(28)30-23(16-27)19-7-6-10-22(15-19)29-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3/t23-,24+/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Esfenvalerate 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate 03Nov2014 2014 doi:10.2903/j.efsa.2014.3873
+Esfenvalerate 66230-04-4 single chemical entity Component is identical to the substance Esfenvalerate 66230-04-4 (alphaS)-alpha-cyano-3-phenoxybenzyl(2S)-2-(4-chlorophenyl)-3-methylbutyrate Esfenvalerate C25H22ClNO3 CC(C)C(C1=CC=C(C=C1)Cl)C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C25H22ClNO3/c1-17(2)24(18-11-13-20(26)14-12-18)25(28)30-23(16-27)19-7-6-10-22(15-19)29-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3/t23-,24+/m1/s1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Esfenvalerate 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate 03Nov2014 2014 doi:10.2903/j.efsa.2014.3873
+Esfenvalerate 66230-04-4 single chemical entity Component is identical to the substance Esfenvalerate 66230-04-4 (alphaS)-alpha-cyano-3-phenoxybenzyl(2S)-2-(4-chlorophenyl)-3-methylbutyrate Esfenvalerate C25H22ClNO3 CC(C)C(C1=CC=C(C=C1)Cl)C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C25H22ClNO3/c1-17(2)24(18-11-13-20(26)14-12-18)25(28)30-23(16-27)19-7-6-10-22(15-19)29-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3/t23-,24+/m1/s1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Esfenvalerate 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate 03Nov2014 2014 doi:10.2903/j.efsa.2014.3873
+Esfenvalerate 66230-04-4 single chemical entity Component is identical to the substance Esfenvalerate 66230-04-4 (alphaS)-alpha-cyano-3-phenoxybenzyl(2S)-2-(4-chlorophenyl)-3-methylbutyrate Esfenvalerate C25H22ClNO3 CC(C)C(C1=CC=C(C=C1)Cl)C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C25H22ClNO3/c1-17(2)24(18-11-13-20(26)14-12-18)25(28)30-23(16-27)19-7-6-10-22(15-19)29-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3/t23-,24+/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Esfenvalerate 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate 03Nov2014 2014 doi:10.2903/j.efsa.2014.3873
+Esfenvalerate 66230-04-4 single chemical entity Component is identical to the substance Esfenvalerate 66230-04-4 (alphaS)-alpha-cyano-3-phenoxybenzyl(2S)-2-(4-chlorophenyl)-3-methylbutyrate Esfenvalerate C25H22ClNO3 CC(C)C(C1=CC=C(C=C1)Cl)C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C25H22ClNO3/c1-17(2)24(18-11-13-20(26)14-12-18)25(28)30-23(16-27)19-7-6-10-22(15-19)29-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3/t23-,24+/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Esfenvalerate 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate 03Nov2014 2014 doi:10.2903/j.efsa.2014.3873
+Esfenvalerate 66230-04-4 single chemical entity Component is identical to the substance Esfenvalerate 66230-04-4 (alphaS)-alpha-cyano-3-phenoxybenzyl(2S)-2-(4-chlorophenyl)-3-methylbutyrate Esfenvalerate C25H22ClNO3 CC(C)C(C1=CC=C(C=C1)Cl)C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C25H22ClNO3/c1-17(2)24(18-11-13-20(26)14-12-18)25(28)30-23(16-27)19-7-6-10-22(15-19)29-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3/t23-,24+/m1/s1 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Human (as organism) HeLa cells Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Esfenvalerate 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate 03Nov2014 2014 doi:10.2903/j.efsa.2014.3873
+Esfenvalerate 66230-04-4 single chemical entity Component is identical to the substance Esfenvalerate 66230-04-4 (alphaS)-alpha-cyano-3-phenoxybenzyl(2S)-2-(4-chlorophenyl)-3-methylbutyrate Esfenvalerate C25H22ClNO3 CC(C)C(C1=CC=C(C=C1)Cl)C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C25H22ClNO3/c1-17(2)24(18-11-13-20(26)14-12-18)25(28)30-23(16-27)19-7-6-10-22(15-19)29-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3/t23-,24+/m1/s1 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Human (as organism) HeLa cells Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Esfenvalerate 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate 03Nov2014 2014 doi:10.2903/j.efsa.2014.3873
+Esfenvalerate 66230-04-4 single chemical entity Component is identical to the substance Esfenvalerate 66230-04-4 (alphaS)-alpha-cyano-3-phenoxybenzyl(2S)-2-(4-chlorophenyl)-3-methylbutyrate Esfenvalerate C25H22ClNO3 CC(C)C(C1=CC=C(C=C1)Cl)C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C25H22ClNO3/c1-17(2)24(18-11-13-20(26)14-12-18)25(28)30-23(16-27)19-7-6-10-22(15-19)29-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3/t23-,24+/m1/s1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) ICR 6 Male intraperitoneal 48.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity RMS: The United Kingdom Esfenvalerate 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate 03Nov2014 2014 doi:10.2903/j.efsa.2014.3873
+Esfenvalerate 66230-04-4 single chemical entity Component is identical to the substance Esfenvalerate 66230-04-4 (alphaS)-alpha-cyano-3-phenoxybenzyl(2S)-2-(4-chlorophenyl)-3-methylbutyrate Esfenvalerate C25H22ClNO3 CC(C)C(C1=CC=C(C=C1)Cl)C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C25H22ClNO3/c1-17(2)24(18-11-13-20(26)14-12-18)25(28)30-23(16-27)19-7-6-10-22(15-19)29-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3/t23-,24+/m1/s1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) ICR 6 Male intraperitoneal 24.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity RMS: The United Kingdom Esfenvalerate 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate 03Nov2014 2014 doi:10.2903/j.efsa.2014.3873
+Esfenvalerate 66230-04-4 single chemical entity Component is identical to the substance Esfenvalerate 66230-04-4 (alphaS)-alpha-cyano-3-phenoxybenzyl(2S)-2-(4-chlorophenyl)-3-methylbutyrate Esfenvalerate C25H22ClNO3 CC(C)C(C1=CC=C(C=C1)Cl)C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C25H22ClNO3/c1-17(2)24(18-11-13-20(26)14-12-18)25(28)30-23(16-27)19-7-6-10-22(15-19)29-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3/t23-,24+/m1/s1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) ICR 6 Male intraperitoneal 72.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity RMS: The United Kingdom Esfenvalerate 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate 03Nov2014 2014 doi:10.2903/j.efsa.2014.3873
+Esfenvalerate 66230-04-4 single chemical entity Component is a metabolite of the substance (2RS,3RS)-3-(4-chlorophenyl)-4-methyl-2-(3-phenoxyphenyl)pentanenitrile 66753-10-4 3-(4-chlorophenyl)-4-methyl-2-(3-phenoxyphenyl)pentanenitrile Not in list C24H22ClNO CC(C)C(C1=CC=C(C=C1)Cl)C(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C24H22ClNO/c1-17(2)24(18-11-13-20(25)14-12-18)23(16-26)19-7-6-10-22(15-19)27-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Esfenvalerate 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate 03Nov2014 2014 doi:10.2903/j.efsa.2014.3873
+Esfenvalerate 66230-04-4 single chemical entity Component is a metabolite of the substance (2RS,3RS)-3-(4-chlorophenyl)-4-methyl-2-(3-phenoxyphenyl)pentanenitrile 66753-10-4 3-(4-chlorophenyl)-4-methyl-2-(3-phenoxyphenyl)pentanenitrile Not in list C24H22ClNO CC(C)C(C1=CC=C(C=C1)Cl)C(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C24H22ClNO/c1-17(2)24(18-11-13-20(25)14-12-18)23(16-26)19-7-6-10-22(15-19)27-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Esfenvalerate 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate 03Nov2014 2014 doi:10.2903/j.efsa.2014.3873
+Esfenvalerate 66230-04-4 single chemical entity Component is a metabolite of the substance (2RS,3RS)-3-(4-chlorophenyl)-4-methyl-2-(3-phenoxyphenyl)pentanenitrile 66753-10-4 3-(4-chlorophenyl)-4-methyl-2-(3-phenoxyphenyl)pentanenitrile Not in list C24H22ClNO CC(C)C(C1=CC=C(C=C1)Cl)C(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C24H22ClNO/c1-17(2)24(18-11-13-20(25)14-12-18)23(16-26)19-7-6-10-22(15-19)27-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Esfenvalerate 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate 03Nov2014 2014 doi:10.2903/j.efsa.2014.3873
+Esfenvalerate 66230-04-4 single chemical entity Component is a metabolite of the substance (2RS,3RS)-3-(4-chlorophenyl)-4-methyl-2-(3-phenoxyphenyl)pentanenitrile 66753-10-4 3-(4-chlorophenyl)-4-methyl-2-(3-phenoxyphenyl)pentanenitrile Not in list C24H22ClNO CC(C)C(C1=CC=C(C=C1)Cl)C(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C24H22ClNO/c1-17(2)24(18-11-13-20(25)14-12-18)23(16-26)19-7-6-10-22(15-19)27-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Esfenvalerate 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate 03Nov2014 2014 doi:10.2903/j.efsa.2014.3873
+Esfenvalerate 66230-04-4 single chemical entity Component is a metabolite of the substance (2RS,3RS)-3-(4-chlorophenyl)-4-methyl-2-(3-phenoxyphenyl)pentanenitrile 66753-10-4 3-(4-chlorophenyl)-4-methyl-2-(3-phenoxyphenyl)pentanenitrile Not in list C24H22ClNO CC(C)C(C1=CC=C(C=C1)Cl)C(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C24H22ClNO/c1-17(2)24(18-11-13-20(25)14-12-18)23(16-26)19-7-6-10-22(15-19)27-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Esfenvalerate 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate 03Nov2014 2014 doi:10.2903/j.efsa.2014.3873
+Esfenvalerate 66230-04-4 single chemical entity Component is a metabolite of the substance (2RS,3RS)-3-(4-chlorophenyl)-4-methyl-2-(3-phenoxyphenyl)pentanenitrile 66753-10-4 3-(4-chlorophenyl)-4-methyl-2-(3-phenoxyphenyl)pentanenitrile Not in list C24H22ClNO CC(C)C(C1=CC=C(C=C1)Cl)C(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C24H22ClNO/c1-17(2)24(18-11-13-20(25)14-12-18)23(16-26)19-7-6-10-22(15-19)27-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Esfenvalerate 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate 03Nov2014 2014 doi:10.2903/j.efsa.2014.3873
+Esfenvalerate 66230-04-4 single chemical entity Component is a metabolite of the substance (2RS,3RS)-3-(4-chlorophenyl)-4-methyl-2-(3-phenoxyphenyl)pentanenitrile 66753-10-4 3-(4-chlorophenyl)-4-methyl-2-(3-phenoxyphenyl)pentanenitrile Not in list C24H22ClNO CC(C)C(C1=CC=C(C=C1)Cl)C(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C24H22ClNO/c1-17(2)24(18-11-13-20(25)14-12-18)23(16-26)19-7-6-10-22(15-19)27-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Esfenvalerate 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate 03Nov2014 2014 doi:10.2903/j.efsa.2014.3873
+Esfenvalerate 66230-04-4 single chemical entity Component is a metabolite of the substance (2RS,3RS)-3-(4-chlorophenyl)-4-methyl-2-(3-phenoxyphenyl)pentanenitrile 66753-10-4 3-(4-chlorophenyl)-4-methyl-2-(3-phenoxyphenyl)pentanenitrile Not in list C24H22ClNO CC(C)C(C1=CC=C(C=C1)Cl)C(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C24H22ClNO/c1-17(2)24(18-11-13-20(25)14-12-18)23(16-26)19-7-6-10-22(15-19)27-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Esfenvalerate 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate 03Nov2014 2014 doi:10.2903/j.efsa.2014.3873
+Esfenvalerate 66230-04-4 single chemical entity Component is a metabolite of the substance (2RS,3RS)-3-(4-chlorophenyl)-4-methyl-2-(3-phenoxyphenyl)pentanenitrile 66753-10-4 3-(4-chlorophenyl)-4-methyl-2-(3-phenoxyphenyl)pentanenitrile Not in list C24H22ClNO CC(C)C(C1=CC=C(C=C1)Cl)C(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C24H22ClNO/c1-17(2)24(18-11-13-20(25)14-12-18)23(16-26)19-7-6-10-22(15-19)27-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Esfenvalerate 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate 03Nov2014 2014 doi:10.2903/j.efsa.2014.3873
+Esfenvalerate 66230-04-4 single chemical entity Component is a metabolite of the substance (2RS,3RS)-3-(4-chlorophenyl)-4-methyl-2-(3-phenoxyphenyl)pentanenitrile 66753-10-4 3-(4-chlorophenyl)-4-methyl-2-(3-phenoxyphenyl)pentanenitrile Not in list C24H22ClNO CC(C)C(C1=CC=C(C=C1)Cl)C(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C24H22ClNO/c1-17(2)24(18-11-13-20(25)14-12-18)23(16-26)19-7-6-10-22(15-19)27-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Esfenvalerate 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate 03Nov2014 2014 doi:10.2903/j.efsa.2014.3873
+Esfenvalerate 66230-04-4 single chemical entity Component is a metabolite of the substance (1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (2RS)-2-(4-chlorophenyl)-3-methylbutanoate (1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (2RS)-2-(4-chlorophenyl)-3-methylbutanoate Not in list C25H24ClNO4 Clc1ccc(cc1)C(C(C)C)C(=O)OC(c3cccc(Oc2ccccc2)c3)C(N)=O InChI=1/C25H24ClNO4/c1-16(2)22(17-11-13-19(26)14-12-17)25(29)31-23(24(27)28)18-7-6-10-21(15-18)30-20-8-4-3-5-9-20/h3-16,22-23H,1-2H3,(H2,27,28) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Esfenvalerate 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate 03Nov2014 2014 doi:10.2903/j.efsa.2014.3873
+Esfenvalerate 66230-04-4 single chemical entity Component is a metabolite of the substance (1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (2RS)-2-(4-chlorophenyl)-3-methylbutanoate (1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (2RS)-2-(4-chlorophenyl)-3-methylbutanoate Not in list C25H24ClNO4 Clc1ccc(cc1)C(C(C)C)C(=O)OC(c3cccc(Oc2ccccc2)c3)C(N)=O InChI=1/C25H24ClNO4/c1-16(2)22(17-11-13-19(26)14-12-17)25(29)31-23(24(27)28)18-7-6-10-21(15-18)30-20-8-4-3-5-9-20/h3-16,22-23H,1-2H3,(H2,27,28) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Esfenvalerate 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate 03Nov2014 2014 doi:10.2903/j.efsa.2014.3873
+Esfenvalerate 66230-04-4 single chemical entity Component is a metabolite of the substance (1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (2RS)-2-(4-chlorophenyl)-3-methylbutanoate (1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (2RS)-2-(4-chlorophenyl)-3-methylbutanoate Not in list C25H24ClNO4 Clc1ccc(cc1)C(C(C)C)C(=O)OC(c3cccc(Oc2ccccc2)c3)C(N)=O InChI=1/C25H24ClNO4/c1-16(2)22(17-11-13-19(26)14-12-17)25(29)31-23(24(27)28)18-7-6-10-21(15-18)30-20-8-4-3-5-9-20/h3-16,22-23H,1-2H3,(H2,27,28) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Esfenvalerate 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate 03Nov2014 2014 doi:10.2903/j.efsa.2014.3873
+Esfenvalerate 66230-04-4 single chemical entity Component is a metabolite of the substance (1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (2RS)-2-(4-chlorophenyl)-3-methylbutanoate (1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (2RS)-2-(4-chlorophenyl)-3-methylbutanoate Not in list C25H24ClNO4 Clc1ccc(cc1)C(C(C)C)C(=O)OC(c3cccc(Oc2ccccc2)c3)C(N)=O InChI=1/C25H24ClNO4/c1-16(2)22(17-11-13-19(26)14-12-17)25(29)31-23(24(27)28)18-7-6-10-21(15-18)30-20-8-4-3-5-9-20/h3-16,22-23H,1-2H3,(H2,27,28) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Esfenvalerate 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate 03Nov2014 2014 doi:10.2903/j.efsa.2014.3873
+Esfenvalerate 66230-04-4 single chemical entity Component is a metabolite of the substance (1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (2RS)-2-(4-chlorophenyl)-3-methylbutanoate (1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (2RS)-2-(4-chlorophenyl)-3-methylbutanoate Not in list C25H24ClNO4 Clc1ccc(cc1)C(C(C)C)C(=O)OC(c3cccc(Oc2ccccc2)c3)C(N)=O InChI=1/C25H24ClNO4/c1-16(2)22(17-11-13-19(26)14-12-17)25(29)31-23(24(27)28)18-7-6-10-21(15-18)30-20-8-4-3-5-9-20/h3-16,22-23H,1-2H3,(H2,27,28) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Esfenvalerate 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate 03Nov2014 2014 doi:10.2903/j.efsa.2014.3873
+Esfenvalerate 66230-04-4 single chemical entity Component is a metabolite of the substance (1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (2RS)-2-(4-chlorophenyl)-3-methylbutanoate (1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (2RS)-2-(4-chlorophenyl)-3-methylbutanoate Not in list C25H24ClNO4 Clc1ccc(cc1)C(C(C)C)C(=O)OC(c3cccc(Oc2ccccc2)c3)C(N)=O InChI=1/C25H24ClNO4/c1-16(2)22(17-11-13-19(26)14-12-17)25(29)31-23(24(27)28)18-7-6-10-21(15-18)30-20-8-4-3-5-9-20/h3-16,22-23H,1-2H3,(H2,27,28) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Esfenvalerate 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate 03Nov2014 2014 doi:10.2903/j.efsa.2014.3873
+Esfenvalerate 66230-04-4 single chemical entity Component is a metabolite of the substance (1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (2RS)-2-(4-chlorophenyl)-3-methylbutanoate (1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (2RS)-2-(4-chlorophenyl)-3-methylbutanoate Not in list C25H24ClNO4 Clc1ccc(cc1)C(C(C)C)C(=O)OC(c3cccc(Oc2ccccc2)c3)C(N)=O InChI=1/C25H24ClNO4/c1-16(2)22(17-11-13-19(26)14-12-17)25(29)31-23(24(27)28)18-7-6-10-21(15-18)30-20-8-4-3-5-9-20/h3-16,22-23H,1-2H3,(H2,27,28) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Esfenvalerate 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate 03Nov2014 2014 doi:10.2903/j.efsa.2014.3873
+Esfenvalerate 66230-04-4 single chemical entity Component is a metabolite of the substance (1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (2RS)-2-(4-chlorophenyl)-3-methylbutanoate (1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (2RS)-2-(4-chlorophenyl)-3-methylbutanoate Not in list C25H24ClNO4 Clc1ccc(cc1)C(C(C)C)C(=O)OC(c3cccc(Oc2ccccc2)c3)C(N)=O InChI=1/C25H24ClNO4/c1-16(2)22(17-11-13-19(26)14-12-17)25(29)31-23(24(27)28)18-7-6-10-21(15-18)30-20-8-4-3-5-9-20/h3-16,22-23H,1-2H3,(H2,27,28) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Esfenvalerate 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate 03Nov2014 2014 doi:10.2903/j.efsa.2014.3873
+Esfenvalerate 66230-04-4 single chemical entity Component is a metabolite of the substance (1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (2RS)-2-(4-chlorophenyl)-3-methylbutanoate (1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (2RS)-2-(4-chlorophenyl)-3-methylbutanoate Not in list C25H24ClNO4 Clc1ccc(cc1)C(C(C)C)C(=O)OC(c3cccc(Oc2ccccc2)c3)C(N)=O InChI=1/C25H24ClNO4/c1-16(2)22(17-11-13-19(26)14-12-17)25(29)31-23(24(27)28)18-7-6-10-21(15-18)30-20-8-4-3-5-9-20/h3-16,22-23H,1-2H3,(H2,27,28) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Esfenvalerate 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate 03Nov2014 2014 doi:10.2903/j.efsa.2014.3873
+Esfenvalerate 66230-04-4 single chemical entity Component is a metabolite of the substance (1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (2RS)-2-(4-chlorophenyl)-3-methylbutanoate (1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (2RS)-2-(4-chlorophenyl)-3-methylbutanoate Not in list C25H24ClNO4 Clc1ccc(cc1)C(C(C)C)C(=O)OC(c3cccc(Oc2ccccc2)c3)C(N)=O InChI=1/C25H24ClNO4/c1-16(2)22(17-11-13-19(26)14-12-17)25(29)31-23(24(27)28)18-7-6-10-21(15-18)30-20-8-4-3-5-9-20/h3-16,22-23H,1-2H3,(H2,27,28) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Esfenvalerate 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate 03Nov2014 2014 doi:10.2903/j.efsa.2014.3873
+Etridiazole 219-991-8 2593-15-9 single chemical entity Component is identical to the substance Etridiazole 219-991-8 2593-15-9 5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole Etridiazole C5H5Cl3N2OS ClC(Cl)(Cl)C1=NSC(OCC)=N1 InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The Netherlands Etridiazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole 04Oct2010 2010 doi:10.2903/j.efsa.2010.1823
+Etridiazole 219-991-8 2593-15-9 single chemical entity Component is identical to the substance Etridiazole 219-991-8 2593-15-9 5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole Etridiazole C5H5Cl3N2OS ClC(Cl)(Cl)C1=NSC(OCC)=N1 InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The Netherlands Etridiazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole 04Oct2010 2010 doi:10.2903/j.efsa.2010.1823
+Etridiazole 219-991-8 2593-15-9 single chemical entity Component is identical to the substance Etridiazole 219-991-8 2593-15-9 5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole Etridiazole C5H5Cl3N2OS ClC(Cl)(Cl)C1=NSC(OCC)=N1 InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The Netherlands Etridiazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole 04Oct2010 2010 doi:10.2903/j.efsa.2010.1823
+Etridiazole 219-991-8 2593-15-9 single chemical entity Component is identical to the substance Etridiazole 219-991-8 2593-15-9 5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole Etridiazole C5H5Cl3N2OS ClC(Cl)(Cl)C1=NSC(OCC)=N1 InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The Netherlands Etridiazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole 04Oct2010 2010 doi:10.2903/j.efsa.2010.1823
+Etridiazole 219-991-8 2593-15-9 single chemical entity Component is identical to the substance Etridiazole 219-991-8 2593-15-9 5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole Etridiazole C5H5Cl3N2OS ClC(Cl)(Cl)C1=NSC(OCC)=N1 InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 Not reported yes without Negative RMS: The Netherlands Etridiazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole 04Oct2010 2010 doi:10.2903/j.efsa.2010.1823
+Etridiazole 219-991-8 2593-15-9 single chemical entity Component is identical to the substance Etridiazole 219-991-8 2593-15-9 5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole Etridiazole C5H5Cl3N2OS ClC(Cl)(Cl)C1=NSC(OCC)=N1 InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) CM571 Not reported yes without Negative RMS: The Netherlands Etridiazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole 04Oct2010 2010 doi:10.2903/j.efsa.2010.1823
+Etridiazole 219-991-8 2593-15-9 single chemical entity Component is identical to the substance Etridiazole 219-991-8 2593-15-9 5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole Etridiazole C5H5Cl3N2OS ClC(Cl)(Cl)C1=NSC(OCC)=N1 InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The Netherlands Etridiazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole 04Oct2010 2010 doi:10.2903/j.efsa.2010.1823
+Etridiazole 219-991-8 2593-15-9 single chemical entity Component is identical to the substance Etridiazole 219-991-8 2593-15-9 5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole Etridiazole C5H5Cl3N2OS ClC(Cl)(Cl)C1=NSC(OCC)=N1 InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The Netherlands Etridiazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole 04Oct2010 2010 doi:10.2903/j.efsa.2010.1823
+Etridiazole 219-991-8 2593-15-9 single chemical entity Component is identical to the substance Etridiazole 219-991-8 2593-15-9 5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole Etridiazole C5H5Cl3N2OS ClC(Cl)(Cl)C1=NSC(OCC)=N1 InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The Netherlands Etridiazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole 04Oct2010 2010 doi:10.2903/j.efsa.2010.1823
+Etridiazole 219-991-8 2593-15-9 single chemical entity Component is identical to the substance Etridiazole 219-991-8 2593-15-9 5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole Etridiazole C5H5Cl3N2OS ClC(Cl)(Cl)C1=NSC(OCC)=N1 InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: The Netherlands Etridiazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole 04Oct2010 2010 doi:10.2903/j.efsa.2010.1823
+Etridiazole 219-991-8 2593-15-9 single chemical entity Component is identical to the substance Etridiazole 219-991-8 2593-15-9 5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole Etridiazole C5H5Cl3N2OS ClC(Cl)(Cl)C1=NSC(OCC)=N1 InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP67 Not reported yes without Negative RMS: The Netherlands Etridiazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole 04Oct2010 2010 doi:10.2903/j.efsa.2010.1823
+Etridiazole 219-991-8 2593-15-9 single chemical entity Component is identical to the substance Etridiazole 219-991-8 2593-15-9 5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole Etridiazole C5H5Cl3N2OS ClC(Cl)(Cl)C1=NSC(OCC)=N1 InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The Netherlands Etridiazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole 04Oct2010 2010 doi:10.2903/j.efsa.2010.1823
+Etridiazole 219-991-8 2593-15-9 single chemical entity Component is identical to the substance Etridiazole 219-991-8 2593-15-9 5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole Etridiazole C5H5Cl3N2OS ClC(Cl)(Cl)C1=NSC(OCC)=N1 InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The Netherlands Etridiazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole 04Oct2010 2010 doi:10.2903/j.efsa.2010.1823
+Etridiazole 219-991-8 2593-15-9 single chemical entity Component is identical to the substance Etridiazole 219-991-8 2593-15-9 5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole Etridiazole C5H5Cl3N2OS ClC(Cl)(Cl)C1=NSC(OCC)=N1 InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) CM611 Not reported yes without Negative RMS: The Netherlands Etridiazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole 04Oct2010 2010 doi:10.2903/j.efsa.2010.1823
+Etridiazole 219-991-8 2593-15-9 single chemical entity Component is identical to the substance Etridiazole 219-991-8 2593-15-9 5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole Etridiazole C5H5Cl3N2OS ClC(Cl)(Cl)C1=NSC(OCC)=N1 InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The Netherlands Etridiazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole 04Oct2010 2010 doi:10.2903/j.efsa.2010.1823
+Etridiazole 219-991-8 2593-15-9 single chemical entity Component is identical to the substance Etridiazole 219-991-8 2593-15-9 5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole Etridiazole C5H5Cl3N2OS ClC(Cl)(Cl)C1=NSC(OCC)=N1 InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: The Netherlands Etridiazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole 04Oct2010 2010 doi:10.2903/j.efsa.2010.1823
+Etridiazole 219-991-8 2593-15-9 single chemical entity Component is identical to the substance Etridiazole 219-991-8 2593-15-9 5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole Etridiazole C5H5Cl3N2OS ClC(Cl)(Cl)C1=NSC(OCC)=N1 InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The Netherlands Etridiazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole 04Oct2010 2010 doi:10.2903/j.efsa.2010.1823
+Etridiazole 219-991-8 2593-15-9 single chemical entity Component is identical to the substance Etridiazole 219-991-8 2593-15-9 5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole Etridiazole C5H5Cl3N2OS ClC(Cl)(Cl)C1=NSC(OCC)=N1 InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP6 Not reported yes without Negative RMS: The Netherlands Etridiazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole 04Oct2010 2010 doi:10.2903/j.efsa.2010.1823
+Etridiazole 219-991-8 2593-15-9 single chemical entity Component is identical to the substance Etridiazole 219-991-8 2593-15-9 5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole Etridiazole C5H5Cl3N2OS ClC(Cl)(Cl)C1=NSC(OCC)=N1 InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: The Netherlands Etridiazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole 04Oct2010 2010 doi:10.2903/j.efsa.2010.1823
+Etridiazole 219-991-8 2593-15-9 single chemical entity Component is identical to the substance Etridiazole 219-991-8 2593-15-9 5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole Etridiazole C5H5Cl3N2OS ClC(Cl)(Cl)C1=NSC(OCC)=N1 InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The Netherlands Etridiazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole 04Oct2010 2010 doi:10.2903/j.efsa.2010.1823
+Etridiazole 219-991-8 2593-15-9 single chemical entity Component is identical to the substance Etridiazole 219-991-8 2593-15-9 5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole Etridiazole C5H5Cl3N2OS ClC(Cl)(Cl)C1=NSC(OCC)=N1 InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: The Netherlands Etridiazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole 04Oct2010 2010 doi:10.2903/j.efsa.2010.1823
+Etridiazole 219-991-8 2593-15-9 single chemical entity Component is identical to the substance Etridiazole 219-991-8 2593-15-9 5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole Etridiazole C5H5Cl3N2OS ClC(Cl)(Cl)C1=NSC(OCC)=N1 InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: The Netherlands Etridiazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole 04Oct2010 2010 doi:10.2903/j.efsa.2010.1823
+Etridiazole 219-991-8 2593-15-9 single chemical entity Component is identical to the substance Etridiazole 219-991-8 2593-15-9 5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole Etridiazole C5H5Cl3N2OS ClC(Cl)(Cl)C1=NSC(OCC)=N1 InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3 organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) Yes Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: The Netherlands Etridiazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole 04Oct2010 2010 doi:10.2903/j.efsa.2010.1823
+Etridiazole 219-991-8 2593-15-9 single chemical entity Component is identical to the substance Etridiazole 219-991-8 2593-15-9 5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole Etridiazole C5H5Cl3N2OS ClC(Cl)(Cl)C1=NSC(OCC)=N1 InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3 organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) Yes Acceptable Hamster (as animal) CHO Not reported yes without Ambiguous RMS: The Netherlands Etridiazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole 04Oct2010 2010 doi:10.2903/j.efsa.2010.1823
+Etridiazole 219-991-8 2593-15-9 single chemical entity Component is identical to the substance Etridiazole 219-991-8 2593-15-9 5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole Etridiazole C5H5Cl3N2OS ClC(Cl)(Cl)C1=NSC(OCC)=N1 InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3 organic compound Other Other genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro According to OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay) No Acceptable Saccharomyces cerevisiae (as organism) D6 Not reported yes with Negative RMS: The Netherlands Etridiazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole 04Oct2010 2010 doi:10.2903/j.efsa.2010.1823
+Etridiazole 219-991-8 2593-15-9 single chemical entity Component is identical to the substance Etridiazole 219-991-8 2593-15-9 5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole Etridiazole C5H5Cl3N2OS ClC(Cl)(Cl)C1=NSC(OCC)=N1 InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3 organic compound Other Other genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro According to OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay) No Acceptable Saccharomyces cerevisiae (as organism) D6 Not reported yes without Negative RMS: The Netherlands Etridiazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole 04Oct2010 2010 doi:10.2903/j.efsa.2010.1823
+Etridiazole 219-991-8 2593-15-9 single chemical entity Component is identical to the substance Etridiazole 219-991-8 2593-15-9 5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole Etridiazole C5H5Cl3N2OS ClC(Cl)(Cl)C1=NSC(OCC)=N1 InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 36 Male/Female Not reported 72.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity$indirect evidence-systemic toxicity RMS: The Netherlands Etridiazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole 04Oct2010 2010 doi:10.2903/j.efsa.2010.1823
+Etridiazole 219-991-8 2593-15-9 single chemical entity Component is identical to the substance Etridiazole 219-991-8 2593-15-9 5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole Etridiazole C5H5Cl3N2OS ClC(Cl)(Cl)C1=NSC(OCC)=N1 InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 36 Male/Female Not reported 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: The Netherlands Etridiazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole 04Oct2010 2010 doi:10.2903/j.efsa.2010.1823
+Etridiazole 219-991-8 2593-15-9 single chemical entity Component is identical to the substance Etridiazole 219-991-8 2593-15-9 5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole Etridiazole C5H5Cl3N2OS ClC(Cl)(Cl)C1=NSC(OCC)=N1 InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 36 Male/Female Not reported 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: The Netherlands Etridiazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole 04Oct2010 2010 doi:10.2903/j.efsa.2010.1823
+Etridiazole 219-991-8 2593-15-9 single chemical entity Component is identical to the substance Etridiazole 219-991-8 2593-15-9 5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole Etridiazole C5H5Cl3N2OS ClC(Cl)(Cl)C1=NSC(OCC)=N1 InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Rat (as animal) Sprague-Dawley 42 Male/Female Not reported 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The Netherlands Etridiazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole 04Oct2010 2010 doi:10.2903/j.efsa.2010.1823
+Etridiazole 219-991-8 2593-15-9 single chemical entity Component is identical to the substance Etridiazole 219-991-8 2593-15-9 5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole Etridiazole C5H5Cl3N2OS ClC(Cl)(Cl)C1=NSC(OCC)=N1 InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Rat (as animal) Sprague-Dawley 42 Male/Female Not reported 48.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The Netherlands Etridiazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole 04Oct2010 2010 doi:10.2903/j.efsa.2010.1823
+Etridiazole 219-991-8 2593-15-9 single chemical entity Component is identical to the substance Etridiazole 219-991-8 2593-15-9 5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole Etridiazole C5H5Cl3N2OS ClC(Cl)(Cl)C1=NSC(OCC)=N1 InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Rat (as animal) Sprague-Dawley 42 Male/Female Not reported 6.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The Netherlands Etridiazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole 04Oct2010 2010 doi:10.2903/j.efsa.2010.1823
+Etridiazole 219-991-8 2593-15-9 single chemical entity Component is identical to the substance Etridiazole 219-991-8 2593-15-9 5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole Etridiazole C5H5Cl3N2OS ClC(Cl)(Cl)C1=NSC(OCC)=N1 InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3 organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Sprague-Dawley 5 Male Not reported 2.0000000000 h yes not applicable Negative RMS: The Netherlands Etridiazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole 04Oct2010 2010 doi:10.2903/j.efsa.2010.1823
+Etridiazole 219-991-8 2593-15-9 single chemical entity Component is identical to the substance Etridiazole 219-991-8 2593-15-9 5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole Etridiazole C5H5Cl3N2OS ClC(Cl)(Cl)C1=NSC(OCC)=N1 InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3 organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Sprague-Dawley 5 Male Not reported 16.0000000000 h yes not applicable Negative RMS: The Netherlands Etridiazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole 04Oct2010 2010 doi:10.2903/j.efsa.2010.1823
+Etridiazole 219-991-8 2593-15-9 single chemical entity Component is identical to the substance Etridiazole 219-991-8 2593-15-9 5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole Etridiazole C5H5Cl3N2OS ClC(Cl)(Cl)C1=NSC(OCC)=N1 InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3 organic compound Other Other DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable Rat (as animal) Fischer344 4 Male Not reported 24.0000000000 h yes not applicable Positive RMS: The Netherlands Etridiazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole 04Oct2010 2010 doi:10.2903/j.efsa.2010.1823
+Etridiazole 219-991-8 2593-15-9 single chemical entity Component is identical to the substance Etridiazole 219-991-8 2593-15-9 5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole Etridiazole C5H5Cl3N2OS ClC(Cl)(Cl)C1=NSC(OCC)=N1 InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3 organic compound Other Other DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable Rat (as animal) Fischer344 4 Male Not reported 39.0000000000 h yes not applicable Positive RMS: The Netherlands Etridiazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole 04Oct2010 2010 doi:10.2903/j.efsa.2010.1823
+Etridiazole 219-991-8 2593-15-9 single chemical entity Component is identical to the substance Etridiazole 219-991-8 2593-15-9 5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole Etridiazole C5H5Cl3N2OS ClC(Cl)(Cl)C1=NSC(OCC)=N1 InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3 organic compound Other Other DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable Rat (as animal) Fischer344 4 Male Not reported 48.0000000000 h yes not applicable Positive RMS: The Netherlands Etridiazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole 04Oct2010 2010 doi:10.2903/j.efsa.2010.1823
+Etridiazole 219-991-8 2593-15-9 single chemical entity Component is a metabolite of the substance 5-Ethoxy-1,2,4-thiadiazole-3-carboxylic acid 67472-43-9 5-Ethoxy-1,2,4-thiadiazole-3-carboxylic acid Not in list C5H6N2O3S CCOC1=NC(=NS1)C(=O)O InChI=1S/C5H6N2O3S/c1-2-10-5-6-3(4(8)9)7-11-5/h2H2,1H3,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The Netherlands Etridiazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole 04Oct2010 2010 doi:10.2903/j.efsa.2010.1823
+Etridiazole 219-991-8 2593-15-9 single chemical entity Component is a metabolite of the substance 5-Ethoxy-1,2,4-thiadiazole-3-carboxylic acid 67472-43-9 5-Ethoxy-1,2,4-thiadiazole-3-carboxylic acid Not in list C5H6N2O3S CCOC1=NC(=NS1)C(=O)O InChI=1S/C5H6N2O3S/c1-2-10-5-6-3(4(8)9)7-11-5/h2H2,1H3,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The Netherlands Etridiazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole 04Oct2010 2010 doi:10.2903/j.efsa.2010.1823
+Etridiazole 219-991-8 2593-15-9 single chemical entity Component is a metabolite of the substance 5-Ethoxy-1,2,4-thiadiazole-3-carboxylic acid 67472-43-9 5-Ethoxy-1,2,4-thiadiazole-3-carboxylic acid Not in list C5H6N2O3S CCOC1=NC(=NS1)C(=O)O InChI=1S/C5H6N2O3S/c1-2-10-5-6-3(4(8)9)7-11-5/h2H2,1H3,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: The Netherlands Etridiazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole 04Oct2010 2010 doi:10.2903/j.efsa.2010.1823
+Etridiazole 219-991-8 2593-15-9 single chemical entity Component is a metabolite of the substance 5-Ethoxy-1,2,4-thiadiazole-3-carboxylic acid 67472-43-9 5-Ethoxy-1,2,4-thiadiazole-3-carboxylic acid Not in list C5H6N2O3S CCOC1=NC(=NS1)C(=O)O InChI=1S/C5H6N2O3S/c1-2-10-5-6-3(4(8)9)7-11-5/h2H2,1H3,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The Netherlands Etridiazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole 04Oct2010 2010 doi:10.2903/j.efsa.2010.1823
+Etridiazole 219-991-8 2593-15-9 single chemical entity Component is a metabolite of the substance 5-Ethoxy-1,2,4-thiadiazole-3-carboxylic acid 67472-43-9 5-Ethoxy-1,2,4-thiadiazole-3-carboxylic acid Not in list C5H6N2O3S CCOC1=NC(=NS1)C(=O)O InChI=1S/C5H6N2O3S/c1-2-10-5-6-3(4(8)9)7-11-5/h2H2,1H3,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The Netherlands Etridiazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole 04Oct2010 2010 doi:10.2903/j.efsa.2010.1823
+Etridiazole 219-991-8 2593-15-9 single chemical entity Component is a metabolite of the substance 5-Ethoxy-1,2,4-thiadiazole-3-carboxylic acid 67472-43-9 5-Ethoxy-1,2,4-thiadiazole-3-carboxylic acid Not in list C5H6N2O3S CCOC1=NC(=NS1)C(=O)O InChI=1S/C5H6N2O3S/c1-2-10-5-6-3(4(8)9)7-11-5/h2H2,1H3,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The Netherlands Etridiazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole 04Oct2010 2010 doi:10.2903/j.efsa.2010.1823
+Etridiazole 219-991-8 2593-15-9 single chemical entity Component is a metabolite of the substance 5-Ethoxy-1,2,4-thiadiazole-3-carboxylic acid 67472-43-9 5-Ethoxy-1,2,4-thiadiazole-3-carboxylic acid Not in list C5H6N2O3S CCOC1=NC(=NS1)C(=O)O InChI=1S/C5H6N2O3S/c1-2-10-5-6-3(4(8)9)7-11-5/h2H2,1H3,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The Netherlands Etridiazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole 04Oct2010 2010 doi:10.2903/j.efsa.2010.1823
+Etridiazole 219-991-8 2593-15-9 single chemical entity Component is a metabolite of the substance 5-Ethoxy-1,2,4-thiadiazole-3-carboxylic acid 67472-43-9 5-Ethoxy-1,2,4-thiadiazole-3-carboxylic acid Not in list C5H6N2O3S CCOC1=NC(=NS1)C(=O)O InChI=1S/C5H6N2O3S/c1-2-10-5-6-3(4(8)9)7-11-5/h2H2,1H3,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: The Netherlands Etridiazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole 04Oct2010 2010 doi:10.2903/j.efsa.2010.1823
+Etridiazole 219-991-8 2593-15-9 single chemical entity Component is a metabolite of the substance 5-Ethoxy-1,2,4-thiadiazole-3-carboxylic acid 67472-43-9 5-Ethoxy-1,2,4-thiadiazole-3-carboxylic acid Not in list C5H6N2O3S CCOC1=NC(=NS1)C(=O)O InChI=1S/C5H6N2O3S/c1-2-10-5-6-3(4(8)9)7-11-5/h2H2,1H3,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The Netherlands Etridiazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole 04Oct2010 2010 doi:10.2903/j.efsa.2010.1823
+Etridiazole 219-991-8 2593-15-9 single chemical entity Component is a metabolite of the substance 5-Ethoxy-1,2,4-thiadiazole-3-carboxylic acid 67472-43-9 5-Ethoxy-1,2,4-thiadiazole-3-carboxylic acid Not in list C5H6N2O3S CCOC1=NC(=NS1)C(=O)O InChI=1S/C5H6N2O3S/c1-2-10-5-6-3(4(8)9)7-11-5/h2H2,1H3,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The Netherlands Etridiazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole 04Oct2010 2010 doi:10.2903/j.efsa.2010.1823
+Etridiazole 219-991-8 2593-15-9 single chemical entity Component is a metabolite of the substance 5-Ethoxy-1,2,4-thiadiazole-3-carboxylic acid 67472-43-9 5-Ethoxy-1,2,4-thiadiazole-3-carboxylic acid Not in list C5H6N2O3S CCOC1=NC(=NS1)C(=O)O InChI=1S/C5H6N2O3S/c1-2-10-5-6-3(4(8)9)7-11-5/h2H2,1H3,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes without Positive RMS: The Netherlands Etridiazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole 04Oct2010 2010 doi:10.2903/j.efsa.2010.1823
+Etridiazole 219-991-8 2593-15-9 single chemical entity Component is a metabolite of the substance 5-Ethoxy-1,2,4-thiadiazole-3-carboxylic acid 67472-43-9 5-Ethoxy-1,2,4-thiadiazole-3-carboxylic acid Not in list C5H6N2O3S CCOC1=NC(=NS1)C(=O)O InChI=1S/C5H6N2O3S/c1-2-10-5-6-3(4(8)9)7-11-5/h2H2,1H3,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: The Netherlands Etridiazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole 04Oct2010 2010 doi:10.2903/j.efsa.2010.1823
+Etridiazole 219-991-8 2593-15-9 single chemical entity Component is a metabolite of the substance 5-Ethoxy-1,2,4-thiadiazole-3-carboxylic acid 67472-43-9 5-Ethoxy-1,2,4-thiadiazole-3-carboxylic acid Not in list C5H6N2O3S CCOC1=NC(=NS1)C(=O)O InChI=1S/C5H6N2O3S/c1-2-10-5-6-3(4(8)9)7-11-5/h2H2,1H3,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) ICR 30 Male/Female Not reported 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: The Netherlands Etridiazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole 04Oct2010 2010 doi:10.2903/j.efsa.2010.1823
+Etridiazole 219-991-8 2593-15-9 single chemical entity Component is a metabolite of the substance 5-Ethoxy-1,2,4-thiadiazole-3-carboxylic acid 67472-43-9 5-Ethoxy-1,2,4-thiadiazole-3-carboxylic acid Not in list C5H6N2O3S CCOC1=NC(=NS1)C(=O)O InChI=1S/C5H6N2O3S/c1-2-10-5-6-3(4(8)9)7-11-5/h2H2,1H3,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) ICR 30 Male/Female Not reported 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: The Netherlands Etridiazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole 04Oct2010 2010 doi:10.2903/j.efsa.2010.1823
+Cyflufenamid 180409-60-3 single chemical entity Component is identical to the substance Cyflufenamid 180409-60-3 N-[(cyclopropylmethoxyamino)-[2,3-difluoro-6-(trifluoromethyl)phenyl]methylidene]-2-phenylacetamide Cyflufenamid: sum of cyflufenamid (Z-isomer) and its E-isomer C20H17F5N2O2 C1CC1CONC(=NC(=O)CC2=CC=CC=C2)C3=C(C=CC(=C3F)F)C(F)(F)F InChI=1S/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is identical to the substance Cyflufenamid 180409-60-3 N-[(cyclopropylmethoxyamino)-[2,3-difluoro-6-(trifluoromethyl)phenyl]methylidene]-2-phenylacetamide Cyflufenamid: sum of cyflufenamid (Z-isomer) and its E-isomer C20H17F5N2O2 C1CC1CONC(=NC(=O)CC2=CC=CC=C2)C3=C(C=CC(=C3F)F)C(F)(F)F InChI=1S/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is identical to the substance Cyflufenamid 180409-60-3 N-[(cyclopropylmethoxyamino)-[2,3-difluoro-6-(trifluoromethyl)phenyl]methylidene]-2-phenylacetamide Cyflufenamid: sum of cyflufenamid (Z-isomer) and its E-isomer C20H17F5N2O2 C1CC1CONC(=NC(=O)CC2=CC=CC=C2)C3=C(C=CC(=C3F)F)C(F)(F)F InChI=1S/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) CM891 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is identical to the substance Cyflufenamid 180409-60-3 N-[(cyclopropylmethoxyamino)-[2,3-difluoro-6-(trifluoromethyl)phenyl]methylidene]-2-phenylacetamide Cyflufenamid: sum of cyflufenamid (Z-isomer) and its E-isomer C20H17F5N2O2 C1CC1CONC(=NC(=O)CC2=CC=CC=C2)C3=C(C=CC(=C3F)F)C(F)(F)F InChI=1S/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is identical to the substance Cyflufenamid 180409-60-3 N-[(cyclopropylmethoxyamino)-[2,3-difluoro-6-(trifluoromethyl)phenyl]methylidene]-2-phenylacetamide Cyflufenamid: sum of cyflufenamid (Z-isomer) and its E-isomer C20H17F5N2O2 C1CC1CONC(=NC(=O)CC2=CC=CC=C2)C3=C(C=CC(=C3F)F)C(F)(F)F InChI=1S/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is identical to the substance Cyflufenamid 180409-60-3 N-[(cyclopropylmethoxyamino)-[2,3-difluoro-6-(trifluoromethyl)phenyl]methylidene]-2-phenylacetamide Cyflufenamid: sum of cyflufenamid (Z-isomer) and its E-isomer C20H17F5N2O2 C1CC1CONC(=NC(=O)CC2=CC=CC=C2)C3=C(C=CC(=C3F)F)C(F)(F)F InChI=1S/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is identical to the substance Cyflufenamid 180409-60-3 N-[(cyclopropylmethoxyamino)-[2,3-difluoro-6-(trifluoromethyl)phenyl]methylidene]-2-phenylacetamide Cyflufenamid: sum of cyflufenamid (Z-isomer) and its E-isomer C20H17F5N2O2 C1CC1CONC(=NC(=O)CC2=CC=CC=C2)C3=C(C=CC(=C3F)F)C(F)(F)F InChI=1S/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is identical to the substance Cyflufenamid 180409-60-3 N-[(cyclopropylmethoxyamino)-[2,3-difluoro-6-(trifluoromethyl)phenyl]methylidene]-2-phenylacetamide Cyflufenamid: sum of cyflufenamid (Z-isomer) and its E-isomer C20H17F5N2O2 C1CC1CONC(=NC(=O)CC2=CC=CC=C2)C3=C(C=CC(=C3F)F)C(F)(F)F InChI=1S/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is identical to the substance Cyflufenamid 180409-60-3 N-[(cyclopropylmethoxyamino)-[2,3-difluoro-6-(trifluoromethyl)phenyl]methylidene]-2-phenylacetamide Cyflufenamid: sum of cyflufenamid (Z-isomer) and its E-isomer C20H17F5N2O2 C1CC1CONC(=NC(=O)CC2=CC=CC=C2)C3=C(C=CC(=C3F)F)C(F)(F)F InChI=1S/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is identical to the substance Cyflufenamid 180409-60-3 N-[(cyclopropylmethoxyamino)-[2,3-difluoro-6-(trifluoromethyl)phenyl]methylidene]-2-phenylacetamide Cyflufenamid: sum of cyflufenamid (Z-isomer) and its E-isomer C20H17F5N2O2 C1CC1CONC(=NC(=O)CC2=CC=CC=C2)C3=C(C=CC(=C3F)F)C(F)(F)F InChI=1S/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) CM891 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is identical to the substance Cyflufenamid 180409-60-3 N-[(cyclopropylmethoxyamino)-[2,3-difluoro-6-(trifluoromethyl)phenyl]methylidene]-2-phenylacetamide Cyflufenamid: sum of cyflufenamid (Z-isomer) and its E-isomer C20H17F5N2O2 C1CC1CONC(=NC(=O)CC2=CC=CC=C2)C3=C(C=CC(=C3F)F)C(F)(F)F InChI=1S/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is identical to the substance Cyflufenamid 180409-60-3 N-[(cyclopropylmethoxyamino)-[2,3-difluoro-6-(trifluoromethyl)phenyl]methylidene]-2-phenylacetamide Cyflufenamid: sum of cyflufenamid (Z-isomer) and its E-isomer C20H17F5N2O2 C1CC1CONC(=NC(=O)CC2=CC=CC=C2)C3=C(C=CC(=C3F)F)C(F)(F)F InChI=1S/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is identical to the substance Cyflufenamid 180409-60-3 N-[(cyclopropylmethoxyamino)-[2,3-difluoro-6-(trifluoromethyl)phenyl]methylidene]-2-phenylacetamide Cyflufenamid: sum of cyflufenamid (Z-isomer) and its E-isomer C20H17F5N2O2 C1CC1CONC(=NC(=O)CC2=CC=CC=C2)C3=C(C=CC(=C3F)F)C(F)(F)F InChI=1S/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is identical to the substance Cyflufenamid 180409-60-3 N-[(cyclopropylmethoxyamino)-[2,3-difluoro-6-(trifluoromethyl)phenyl]methylidene]-2-phenylacetamide Cyflufenamid: sum of cyflufenamid (Z-isomer) and its E-isomer C20H17F5N2O2 C1CC1CONC(=NC(=O)CC2=CC=CC=C2)C3=C(C=CC(=C3F)F)C(F)(F)F InChI=1S/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is identical to the substance Cyflufenamid 180409-60-3 N-[(cyclopropylmethoxyamino)-[2,3-difluoro-6-(trifluoromethyl)phenyl]methylidene]-2-phenylacetamide Cyflufenamid: sum of cyflufenamid (Z-isomer) and its E-isomer C20H17F5N2O2 C1CC1CONC(=NC(=O)CC2=CC=CC=C2)C3=C(C=CC(=C3F)F)C(F)(F)F InChI=1S/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is identical to the substance Cyflufenamid 180409-60-3 N-[(cyclopropylmethoxyamino)-[2,3-difluoro-6-(trifluoromethyl)phenyl]methylidene]-2-phenylacetamide Cyflufenamid: sum of cyflufenamid (Z-isomer) and its E-isomer C20H17F5N2O2 C1CC1CONC(=NC(=O)CC2=CC=CC=C2)C3=C(C=CC(=C3F)F)C(F)(F)F InChI=1S/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is identical to the substance Cyflufenamid 180409-60-3 N-[(cyclopropylmethoxyamino)-[2,3-difluoro-6-(trifluoromethyl)phenyl]methylidene]-2-phenylacetamide Cyflufenamid: sum of cyflufenamid (Z-isomer) and its E-isomer C20H17F5N2O2 C1CC1CONC(=NC(=O)CC2=CC=CC=C2)C3=C(C=CC(=C3F)F)C(F)(F)F InChI=1S/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 20 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is identical to the substance Cyflufenamid 180409-60-3 N-[(cyclopropylmethoxyamino)-[2,3-difluoro-6-(trifluoromethyl)phenyl]methylidene]-2-phenylacetamide Cyflufenamid: sum of cyflufenamid (Z-isomer) and its E-isomer C20H17F5N2O2 C1CC1CONC(=NC(=O)CC2=CC=CC=C2)C3=C(C=CC(=C3F)F)C(F)(F)F InChI=1S/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 20 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is identical to the substance Cyflufenamid 180409-60-3 N-[(cyclopropylmethoxyamino)-[2,3-difluoro-6-(trifluoromethyl)phenyl]methylidene]-2-phenylacetamide Cyflufenamid: sum of cyflufenamid (Z-isomer) and its E-isomer C20H17F5N2O2 C1CC1CONC(=NC(=O)CC2=CC=CC=C2)C3=C(C=CC(=C3F)F)C(F)(F)F InChI=1S/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Sprague-Dawley 4 Male oral: gavage 2.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is identical to the substance Cyflufenamid 180409-60-3 N-[(cyclopropylmethoxyamino)-[2,3-difluoro-6-(trifluoromethyl)phenyl]methylidene]-2-phenylacetamide Cyflufenamid: sum of cyflufenamid (Z-isomer) and its E-isomer C20H17F5N2O2 C1CC1CONC(=NC(=O)CC2=CC=CC=C2)C3=C(C=CC(=C3F)F)C(F)(F)F InChI=1S/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Sprague-Dawley 4 Male oral: gavage 14.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide Not in list C12H11F5N2O N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide Not in list C12H11F5N2O N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide Not in list C12H11F5N2O N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide Not in list C12H11F5N2O N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide Not in list C12H11F5N2O N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide Not in list C12H11F5N2O N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide Not in list C12H11F5N2O N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) CM891 Not reported yes with Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide Not in list C12H11F5N2O N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide Not in list C12H11F5N2O N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) CM891 Not reported yes without Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide Not in list C12H11F5N2O N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide Not in list C12H11F5N2O N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide Not in list C12H11F5N2O N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance 2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide 2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide Not in list C8H5F5N2 Fc1c(C(=N)N)c(ccc1F)C(F)(F)F InChI=1/C8H5F5N2/c9-4-2-1-3(8(11,12)13)5(6(4)10)7(14)15/h1-2H,(H3,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance 2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide 2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide Not in list C8H5F5N2 Fc1c(C(=N)N)c(ccc1F)C(F)(F)F InChI=1/C8H5F5N2/c9-4-2-1-3(8(11,12)13)5(6(4)10)7(14)15/h1-2H,(H3,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) CM891 Not reported yes with Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance 2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide 2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide Not in list C8H5F5N2 Fc1c(C(=N)N)c(ccc1F)C(F)(F)F InChI=1/C8H5F5N2/c9-4-2-1-3(8(11,12)13)5(6(4)10)7(14)15/h1-2H,(H3,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance 2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide 2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide Not in list C8H5F5N2 Fc1c(C(=N)N)c(ccc1F)C(F)(F)F InChI=1/C8H5F5N2/c9-4-2-1-3(8(11,12)13)5(6(4)10)7(14)15/h1-2H,(H3,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance 2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide 2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide Not in list C8H5F5N2 Fc1c(C(=N)N)c(ccc1F)C(F)(F)F InChI=1/C8H5F5N2/c9-4-2-1-3(8(11,12)13)5(6(4)10)7(14)15/h1-2H,(H3,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance 2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide 2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide Not in list C8H5F5N2 Fc1c(C(=N)N)c(ccc1F)C(F)(F)F InChI=1/C8H5F5N2/c9-4-2-1-3(8(11,12)13)5(6(4)10)7(14)15/h1-2H,(H3,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) CM891 Not reported yes without Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance 2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide 2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide Not in list C8H5F5N2 Fc1c(C(=N)N)c(ccc1F)C(F)(F)F InChI=1/C8H5F5N2/c9-4-2-1-3(8(11,12)13)5(6(4)10)7(14)15/h1-2H,(H3,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance 2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide 2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide Not in list C8H5F5N2 Fc1c(C(=N)N)c(ccc1F)C(F)(F)F InChI=1/C8H5F5N2/c9-4-2-1-3(8(11,12)13)5(6(4)10)7(14)15/h1-2H,(H3,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance 2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide 2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide Not in list C8H5F5N2 Fc1c(C(=N)N)c(ccc1F)C(F)(F)F InChI=1/C8H5F5N2/c9-4-2-1-3(8(11,12)13)5(6(4)10)7(14)15/h1-2H,(H3,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance 2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide 2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide Not in list C8H5F5N2 Fc1c(C(=N)N)c(ccc1F)C(F)(F)F InChI=1/C8H5F5N2/c9-4-2-1-3(8(11,12)13)5(6(4)10)7(14)15/h1-2H,(H3,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance 2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide 2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide Not in list C8H5F5N2 Fc1c(C(=N)N)c(ccc1F)C(F)(F)F InChI=1/C8H5F5N2/c9-4-2-1-3(8(11,12)13)5(6(4)10)7(14)15/h1-2H,(H3,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance 2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide 2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide Not in list C8H5F5N2 Fc1c(C(=N)N)c(ccc1F)C(F)(F)F InChI=1/C8H5F5N2/c9-4-2-1-3(8(11,12)13)5(6(4)10)7(14)15/h1-2H,(H3,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance 2,3-difluoro-6-(trifluoromethyl)benzamide 2,3-difluoro-6-(trifluoromethyl)benzamide Not in list C8H4F5NO Fc1c(C(N)=O)c(ccc1F)C(F)(F)F InChI=1/C8H4F5NO/c9-4-2-1-3(8(11,12)13)5(6(4)10)7(14)15/h1-2H,(H2,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance 2,3-difluoro-6-(trifluoromethyl)benzamide 2,3-difluoro-6-(trifluoromethyl)benzamide Not in list C8H4F5NO Fc1c(C(N)=O)c(ccc1F)C(F)(F)F InChI=1/C8H4F5NO/c9-4-2-1-3(8(11,12)13)5(6(4)10)7(14)15/h1-2H,(H2,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance 2,3-difluoro-6-(trifluoromethyl)benzamide 2,3-difluoro-6-(trifluoromethyl)benzamide Not in list C8H4F5NO Fc1c(C(N)=O)c(ccc1F)C(F)(F)F InChI=1/C8H4F5NO/c9-4-2-1-3(8(11,12)13)5(6(4)10)7(14)15/h1-2H,(H2,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance 2,3-difluoro-6-(trifluoromethyl)benzamide 2,3-difluoro-6-(trifluoromethyl)benzamide Not in list C8H4F5NO Fc1c(C(N)=O)c(ccc1F)C(F)(F)F InChI=1/C8H4F5NO/c9-4-2-1-3(8(11,12)13)5(6(4)10)7(14)15/h1-2H,(H2,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance 2,3-difluoro-6-(trifluoromethyl)benzamide 2,3-difluoro-6-(trifluoromethyl)benzamide Not in list C8H4F5NO Fc1c(C(N)=O)c(ccc1F)C(F)(F)F InChI=1/C8H4F5NO/c9-4-2-1-3(8(11,12)13)5(6(4)10)7(14)15/h1-2H,(H2,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance 2,3-difluoro-6-(trifluoromethyl)benzamide 2,3-difluoro-6-(trifluoromethyl)benzamide Not in list C8H4F5NO Fc1c(C(N)=O)c(ccc1F)C(F)(F)F InChI=1/C8H4F5NO/c9-4-2-1-3(8(11,12)13)5(6(4)10)7(14)15/h1-2H,(H2,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance 2,3-difluoro-6-(trifluoromethyl)benzamide 2,3-difluoro-6-(trifluoromethyl)benzamide Not in list C8H4F5NO Fc1c(C(N)=O)c(ccc1F)C(F)(F)F InChI=1/C8H4F5NO/c9-4-2-1-3(8(11,12)13)5(6(4)10)7(14)15/h1-2H,(H2,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance 2,3-difluoro-6-(trifluoromethyl)benzamide 2,3-difluoro-6-(trifluoromethyl)benzamide Not in list C8H4F5NO Fc1c(C(N)=O)c(ccc1F)C(F)(F)F InChI=1/C8H4F5NO/c9-4-2-1-3(8(11,12)13)5(6(4)10)7(14)15/h1-2H,(H2,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) CM891 Not reported yes with Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance 2,3-difluoro-6-(trifluoromethyl)benzamide 2,3-difluoro-6-(trifluoromethyl)benzamide Not in list C8H4F5NO Fc1c(C(N)=O)c(ccc1F)C(F)(F)F InChI=1/C8H4F5NO/c9-4-2-1-3(8(11,12)13)5(6(4)10)7(14)15/h1-2H,(H2,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance 2,3-difluoro-6-(trifluoromethyl)benzamide 2,3-difluoro-6-(trifluoromethyl)benzamide Not in list C8H4F5NO Fc1c(C(N)=O)c(ccc1F)C(F)(F)F InChI=1/C8H4F5NO/c9-4-2-1-3(8(11,12)13)5(6(4)10)7(14)15/h1-2H,(H2,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance 2,3-difluoro-6-(trifluoromethyl)benzamide 2,3-difluoro-6-(trifluoromethyl)benzamide Not in list C8H4F5NO Fc1c(C(N)=O)c(ccc1F)C(F)(F)F InChI=1/C8H4F5NO/c9-4-2-1-3(8(11,12)13)5(6(4)10)7(14)15/h1-2H,(H2,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) CM891 Not reported yes without Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance 2,3-difluoro-6-(trifluoromethyl)benzamide 2,3-difluoro-6-(trifluoromethyl)benzamide Not in list C8H4F5NO Fc1c(C(N)=O)c(ccc1F)C(F)(F)F InChI=1/C8H4F5NO/c9-4-2-1-3(8(11,12)13)5(6(4)10)7(14)15/h1-2H,(H2,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance 3-({(Z)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}amino)-3-oxopropanoic acid 3-({(Z)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}amino)-3-oxopropanoic acid Not in list C15H13F5N2O4 FC(F)(F)c2ccc(F)c(F)c2C(\NC(=O)CC(=O)O)=N\OCC1CC1 InChI=1/C15H13F5N2O4/c16-9-4-3-8(15(18,19)20)12(13(9)17)14(21-10(23)5-11(24)25)22-26-6-7-1-2-7/h3-4,7H,1-2,5-6H2,(H,24,25)(H,21,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance 3-({(Z)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}amino)-3-oxopropanoic acid 3-({(Z)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}amino)-3-oxopropanoic acid Not in list C15H13F5N2O4 FC(F)(F)c2ccc(F)c(F)c2C(\NC(=O)CC(=O)O)=N\OCC1CC1 InChI=1/C15H13F5N2O4/c16-9-4-3-8(15(18,19)20)12(13(9)17)14(21-10(23)5-11(24)25)22-26-6-7-1-2-7/h3-4,7H,1-2,5-6H2,(H,24,25)(H,21,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance 3-({(Z)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}amino)-3-oxopropanoic acid 3-({(Z)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}amino)-3-oxopropanoic acid Not in list C15H13F5N2O4 FC(F)(F)c2ccc(F)c(F)c2C(\NC(=O)CC(=O)O)=N\OCC1CC1 InChI=1/C15H13F5N2O4/c16-9-4-3-8(15(18,19)20)12(13(9)17)14(21-10(23)5-11(24)25)22-26-6-7-1-2-7/h3-4,7H,1-2,5-6H2,(H,24,25)(H,21,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) CM891 Not reported yes without Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance 3-({(Z)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}amino)-3-oxopropanoic acid 3-({(Z)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}amino)-3-oxopropanoic acid Not in list C15H13F5N2O4 FC(F)(F)c2ccc(F)c(F)c2C(\NC(=O)CC(=O)O)=N\OCC1CC1 InChI=1/C15H13F5N2O4/c16-9-4-3-8(15(18,19)20)12(13(9)17)14(21-10(23)5-11(24)25)22-26-6-7-1-2-7/h3-4,7H,1-2,5-6H2,(H,24,25)(H,21,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance 3-({(Z)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}amino)-3-oxopropanoic acid 3-({(Z)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}amino)-3-oxopropanoic acid Not in list C15H13F5N2O4 FC(F)(F)c2ccc(F)c(F)c2C(\NC(=O)CC(=O)O)=N\OCC1CC1 InChI=1/C15H13F5N2O4/c16-9-4-3-8(15(18,19)20)12(13(9)17)14(21-10(23)5-11(24)25)22-26-6-7-1-2-7/h3-4,7H,1-2,5-6H2,(H,24,25)(H,21,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance 3-({(Z)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}amino)-3-oxopropanoic acid 3-({(Z)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}amino)-3-oxopropanoic acid Not in list C15H13F5N2O4 FC(F)(F)c2ccc(F)c(F)c2C(\NC(=O)CC(=O)O)=N\OCC1CC1 InChI=1/C15H13F5N2O4/c16-9-4-3-8(15(18,19)20)12(13(9)17)14(21-10(23)5-11(24)25)22-26-6-7-1-2-7/h3-4,7H,1-2,5-6H2,(H,24,25)(H,21,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance 3-({(Z)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}amino)-3-oxopropanoic acid 3-({(Z)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}amino)-3-oxopropanoic acid Not in list C15H13F5N2O4 FC(F)(F)c2ccc(F)c(F)c2C(\NC(=O)CC(=O)O)=N\OCC1CC1 InChI=1/C15H13F5N2O4/c16-9-4-3-8(15(18,19)20)12(13(9)17)14(21-10(23)5-11(24)25)22-26-6-7-1-2-7/h3-4,7H,1-2,5-6H2,(H,24,25)(H,21,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance 3-({(Z)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}amino)-3-oxopropanoic acid 3-({(Z)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}amino)-3-oxopropanoic acid Not in list C15H13F5N2O4 FC(F)(F)c2ccc(F)c(F)c2C(\NC(=O)CC(=O)O)=N\OCC1CC1 InChI=1/C15H13F5N2O4/c16-9-4-3-8(15(18,19)20)12(13(9)17)14(21-10(23)5-11(24)25)22-26-6-7-1-2-7/h3-4,7H,1-2,5-6H2,(H,24,25)(H,21,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance 3-({(Z)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}amino)-3-oxopropanoic acid 3-({(Z)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}amino)-3-oxopropanoic acid Not in list C15H13F5N2O4 FC(F)(F)c2ccc(F)c(F)c2C(\NC(=O)CC(=O)O)=N\OCC1CC1 InChI=1/C15H13F5N2O4/c16-9-4-3-8(15(18,19)20)12(13(9)17)14(21-10(23)5-11(24)25)22-26-6-7-1-2-7/h3-4,7H,1-2,5-6H2,(H,24,25)(H,21,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance 3-({(Z)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}amino)-3-oxopropanoic acid 3-({(Z)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}amino)-3-oxopropanoic acid Not in list C15H13F5N2O4 FC(F)(F)c2ccc(F)c(F)c2C(\NC(=O)CC(=O)O)=N\OCC1CC1 InChI=1/C15H13F5N2O4/c16-9-4-3-8(15(18,19)20)12(13(9)17)14(21-10(23)5-11(24)25)22-26-6-7-1-2-7/h3-4,7H,1-2,5-6H2,(H,24,25)(H,21,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance 3-({(Z)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}amino)-3-oxopropanoic acid 3-({(Z)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}amino)-3-oxopropanoic acid Not in list C15H13F5N2O4 FC(F)(F)c2ccc(F)c(F)c2C(\NC(=O)CC(=O)O)=N\OCC1CC1 InChI=1/C15H13F5N2O4/c16-9-4-3-8(15(18,19)20)12(13(9)17)14(21-10(23)5-11(24)25)22-26-6-7-1-2-7/h3-4,7H,1-2,5-6H2,(H,24,25)(H,21,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance 3-({(Z)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}amino)-3-oxopropanoic acid 3-({(Z)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}amino)-3-oxopropanoic acid Not in list C15H13F5N2O4 FC(F)(F)c2ccc(F)c(F)c2C(\NC(=O)CC(=O)O)=N\OCC1CC1 InChI=1/C15H13F5N2O4/c16-9-4-3-8(15(18,19)20)12(13(9)17)14(21-10(23)5-11(24)25)22-26-6-7-1-2-7/h3-4,7H,1-2,5-6H2,(H,24,25)(H,21,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) CM891 Not reported yes with Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance N-{(E)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}-2-phenylacetamide N-{(E)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}-2-phenylacetamide Not in list C20H17F5N2O2 FC(F)(F)c3ccc(F)c(F)c3C(/NC(=O)Cc1ccccc1)=N\OCC2CC2 InChI=1/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) CM891 Not reported yes without Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance N-{(E)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}-2-phenylacetamide N-{(E)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}-2-phenylacetamide Not in list C20H17F5N2O2 FC(F)(F)c3ccc(F)c(F)c3C(/NC(=O)Cc1ccccc1)=N\OCC2CC2 InChI=1/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance N-{(E)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}-2-phenylacetamide N-{(E)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}-2-phenylacetamide Not in list C20H17F5N2O2 FC(F)(F)c3ccc(F)c(F)c3C(/NC(=O)Cc1ccccc1)=N\OCC2CC2 InChI=1/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance N-{(E)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}-2-phenylacetamide N-{(E)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}-2-phenylacetamide Not in list C20H17F5N2O2 FC(F)(F)c3ccc(F)c(F)c3C(/NC(=O)Cc1ccccc1)=N\OCC2CC2 InChI=1/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance N-{(E)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}-2-phenylacetamide N-{(E)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}-2-phenylacetamide Not in list C20H17F5N2O2 FC(F)(F)c3ccc(F)c(F)c3C(/NC(=O)Cc1ccccc1)=N\OCC2CC2 InChI=1/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) CM891 Not reported yes with Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance N-{(E)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}-2-phenylacetamide N-{(E)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}-2-phenylacetamide Not in list C20H17F5N2O2 FC(F)(F)c3ccc(F)c(F)c3C(/NC(=O)Cc1ccccc1)=N\OCC2CC2 InChI=1/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance N-{(E)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}-2-phenylacetamide N-{(E)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}-2-phenylacetamide Not in list C20H17F5N2O2 FC(F)(F)c3ccc(F)c(F)c3C(/NC(=O)Cc1ccccc1)=N\OCC2CC2 InChI=1/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance N-{(E)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}-2-phenylacetamide N-{(E)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}-2-phenylacetamide Not in list C20H17F5N2O2 FC(F)(F)c3ccc(F)c(F)c3C(/NC(=O)Cc1ccccc1)=N\OCC2CC2 InChI=1/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance N-{(E)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}-2-phenylacetamide N-{(E)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}-2-phenylacetamide Not in list C20H17F5N2O2 FC(F)(F)c3ccc(F)c(F)c3C(/NC(=O)Cc1ccccc1)=N\OCC2CC2 InChI=1/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance N-{(E)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}-2-phenylacetamide N-{(E)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}-2-phenylacetamide Not in list C20H17F5N2O2 FC(F)(F)c3ccc(F)c(F)c3C(/NC(=O)Cc1ccccc1)=N\OCC2CC2 InChI=1/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance N-{(E)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}-2-phenylacetamide N-{(E)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}-2-phenylacetamide Not in list C20H17F5N2O2 FC(F)(F)c3ccc(F)c(F)c3C(/NC(=O)Cc1ccccc1)=N\OCC2CC2 InChI=1/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance N-{(E)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}-2-phenylacetamide N-{(E)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}-2-phenylacetamide Not in list C20H17F5N2O2 FC(F)(F)c3ccc(F)c(F)c3C(/NC(=O)Cc1ccccc1)=N\OCC2CC2 InChI=1/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance cyclopropanecarboxylic acid 217-162-5 1759-53 cyclopropanecarboxylic acid Not in list C4H6O2 C1CC1C(=O)O InChI=1S/C4H6O2/c5-4(6)3-1-2-3/h3H,1-2H2,(H,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance cyclopropanecarboxylic acid 217-162-5 1759-53 cyclopropanecarboxylic acid Not in list C4H6O2 C1CC1C(=O)O InChI=1S/C4H6O2/c5-4(6)3-1-2-3/h3H,1-2H2,(H,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) CM891 Not reported yes without Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance cyclopropanecarboxylic acid 217-162-5 1759-53 cyclopropanecarboxylic acid Not in list C4H6O2 C1CC1C(=O)O InChI=1S/C4H6O2/c5-4(6)3-1-2-3/h3H,1-2H2,(H,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance cyclopropanecarboxylic acid 217-162-5 1759-53 cyclopropanecarboxylic acid Not in list C4H6O2 C1CC1C(=O)O InChI=1S/C4H6O2/c5-4(6)3-1-2-3/h3H,1-2H2,(H,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance cyclopropanecarboxylic acid 217-162-5 1759-53 cyclopropanecarboxylic acid Not in list C4H6O2 C1CC1C(=O)O InChI=1S/C4H6O2/c5-4(6)3-1-2-3/h3H,1-2H2,(H,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance cyclopropanecarboxylic acid 217-162-5 1759-53 cyclopropanecarboxylic acid Not in list C4H6O2 C1CC1C(=O)O InChI=1S/C4H6O2/c5-4(6)3-1-2-3/h3H,1-2H2,(H,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) CM891 Not reported yes with Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance cyclopropanecarboxylic acid 217-162-5 1759-53 cyclopropanecarboxylic acid Not in list C4H6O2 C1CC1C(=O)O InChI=1S/C4H6O2/c5-4(6)3-1-2-3/h3H,1-2H2,(H,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance cyclopropanecarboxylic acid 217-162-5 1759-53 cyclopropanecarboxylic acid Not in list C4H6O2 C1CC1C(=O)O InChI=1S/C4H6O2/c5-4(6)3-1-2-3/h3H,1-2H2,(H,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance cyclopropanecarboxylic acid 217-162-5 1759-53 cyclopropanecarboxylic acid Not in list C4H6O2 C1CC1C(=O)O InChI=1S/C4H6O2/c5-4(6)3-1-2-3/h3H,1-2H2,(H,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance cyclopropanecarboxylic acid 217-162-5 1759-53 cyclopropanecarboxylic acid Not in list C4H6O2 C1CC1C(=O)O InChI=1S/C4H6O2/c5-4(6)3-1-2-3/h3H,1-2H2,(H,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance cyclopropanecarboxylic acid 217-162-5 1759-53 cyclopropanecarboxylic acid Not in list C4H6O2 C1CC1C(=O)O InChI=1S/C4H6O2/c5-4(6)3-1-2-3/h3H,1-2H2,(H,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance cyclopropanecarboxylic acid 217-162-5 1759-53 cyclopropanecarboxylic acid Not in list C4H6O2 C1CC1C(=O)O InChI=1S/C4H6O2/c5-4(6)3-1-2-3/h3H,1-2H2,(H,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance cyclopropylmethanol 219-735-5 2516-33-8 cyclopropylmethanol Not in list C4H8O C1CC1CO InChI=1S/C4H8O/c5-3-4-1-2-4/h4-5H,1-3H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance cyclopropylmethanol 219-735-5 2516-33-8 cyclopropylmethanol Not in list C4H8O C1CC1CO InChI=1S/C4H8O/c5-3-4-1-2-4/h4-5H,1-3H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) CM891 Not reported yes with Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance cyclopropylmethanol 219-735-5 2516-33-8 cyclopropylmethanol Not in list C4H8O C1CC1CO InChI=1S/C4H8O/c5-3-4-1-2-4/h4-5H,1-3H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance cyclopropylmethanol 219-735-5 2516-33-8 cyclopropylmethanol Not in list C4H8O C1CC1CO InChI=1S/C4H8O/c5-3-4-1-2-4/h4-5H,1-3H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance cyclopropylmethanol 219-735-5 2516-33-8 cyclopropylmethanol Not in list C4H8O C1CC1CO InChI=1S/C4H8O/c5-3-4-1-2-4/h4-5H,1-3H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance cyclopropylmethanol 219-735-5 2516-33-8 cyclopropylmethanol Not in list C4H8O C1CC1CO InChI=1S/C4H8O/c5-3-4-1-2-4/h4-5H,1-3H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance cyclopropylmethanol 219-735-5 2516-33-8 cyclopropylmethanol Not in list C4H8O C1CC1CO InChI=1S/C4H8O/c5-3-4-1-2-4/h4-5H,1-3H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance cyclopropylmethanol 219-735-5 2516-33-8 cyclopropylmethanol Not in list C4H8O C1CC1CO InChI=1S/C4H8O/c5-3-4-1-2-4/h4-5H,1-3H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) CM891 Not reported yes without Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance cyclopropylmethanol 219-735-5 2516-33-8 cyclopropylmethanol Not in list C4H8O C1CC1CO InChI=1S/C4H8O/c5-3-4-1-2-4/h4-5H,1-3H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance cyclopropylmethanol 219-735-5 2516-33-8 cyclopropylmethanol Not in list C4H8O C1CC1CO InChI=1S/C4H8O/c5-3-4-1-2-4/h4-5H,1-3H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance cyclopropylmethanol 219-735-5 2516-33-8 cyclopropylmethanol Not in list C4H8O C1CC1CO InChI=1S/C4H8O/c5-3-4-1-2-4/h4-5H,1-3H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyflufenamid 180409-60-3 single chemical entity Component is a metabolite of the substance cyclopropylmethanol 219-735-5 2516-33-8 cyclopropylmethanol Not in list C4H8O C1CC1CO InChI=1S/C4H8O/c5-3-4-1-2-4/h4-5H,1-3H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The United Kingdom Cyflufenamid 2006 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance cyflufenamid 29May2009 2009 doi:10.2903/j.efsa.2009.258r
+Cyproconazole 94361-06-5 single chemical entity Component is identical to the substance Cyproconazole 94361-06-5 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Cyproconazole C15H18ClN3O ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1 InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Ireland Cyproconazole 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole 25Nov2010 2010 doi:10.2903/j.efsa.2010.1897
+Cyproconazole 94361-06-5 single chemical entity Component is identical to the substance Cyproconazole 94361-06-5 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Cyproconazole C15H18ClN3O ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1 InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Ireland Cyproconazole 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole 25Nov2010 2010 doi:10.2903/j.efsa.2010.1897
+Cyproconazole 94361-06-5 single chemical entity Component is identical to the substance Cyproconazole 94361-06-5 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Cyproconazole C15H18ClN3O ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1 InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Ireland Cyproconazole 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole 25Nov2010 2010 doi:10.2903/j.efsa.2010.1897
+Cyproconazole 94361-06-5 single chemical entity Component is identical to the substance Cyproconazole 94361-06-5 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Cyproconazole C15H18ClN3O ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1 InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Ireland Cyproconazole 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole 25Nov2010 2010 doi:10.2903/j.efsa.2010.1897
+Cyproconazole 94361-06-5 single chemical entity Component is identical to the substance Cyproconazole 94361-06-5 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Cyproconazole C15H18ClN3O ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1 InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Ireland Cyproconazole 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole 25Nov2010 2010 doi:10.2903/j.efsa.2010.1897
+Cyproconazole 94361-06-5 single chemical entity Component is identical to the substance Cyproconazole 94361-06-5 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Cyproconazole C15H18ClN3O ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1 InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Ireland Cyproconazole 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole 25Nov2010 2010 doi:10.2903/j.efsa.2010.1897
+Cyproconazole 94361-06-5 single chemical entity Component is identical to the substance Cyproconazole 94361-06-5 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Cyproconazole C15H18ClN3O ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1 InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Ireland Cyproconazole 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole 25Nov2010 2010 doi:10.2903/j.efsa.2010.1897
+Cyproconazole 94361-06-5 single chemical entity Component is identical to the substance Cyproconazole 94361-06-5 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Cyproconazole C15H18ClN3O ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1 InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Ireland Cyproconazole 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole 25Nov2010 2010 doi:10.2903/j.efsa.2010.1897
+Cyproconazole 94361-06-5 single chemical entity Component is identical to the substance Cyproconazole 94361-06-5 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Cyproconazole C15H18ClN3O ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1 InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Ireland Cyproconazole 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole 25Nov2010 2010 doi:10.2903/j.efsa.2010.1897
+Cyproconazole 94361-06-5 single chemical entity Component is identical to the substance Cyproconazole 94361-06-5 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Cyproconazole C15H18ClN3O ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1 InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Ireland Cyproconazole 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole 25Nov2010 2010 doi:10.2903/j.efsa.2010.1897
+Cyproconazole 94361-06-5 single chemical entity Component is identical to the substance Cyproconazole 94361-06-5 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Cyproconazole C15H18ClN3O ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1 InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Ireland Cyproconazole 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole 25Nov2010 2010 doi:10.2903/j.efsa.2010.1897
+Cyproconazole 94361-06-5 single chemical entity Component is identical to the substance Cyproconazole 94361-06-5 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Cyproconazole C15H18ClN3O ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1 InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Ireland Cyproconazole 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole 25Nov2010 2010 doi:10.2903/j.efsa.2010.1897
+Cyproconazole 94361-06-5 single chemical entity Component is identical to the substance Cyproconazole 94361-06-5 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Cyproconazole C15H18ClN3O ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1 InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) Not reported Not reported yes, concurrent vehicle with Negative RMS: Ireland Cyproconazole 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole 25Nov2010 2010 doi:10.2903/j.efsa.2010.1897
+Cyproconazole 94361-06-5 single chemical entity Component is identical to the substance Cyproconazole 94361-06-5 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Cyproconazole C15H18ClN3O ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1 InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) Not reported Not reported yes, concurrent vehicle without Negative RMS: Ireland Cyproconazole 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole 25Nov2010 2010 doi:10.2903/j.efsa.2010.1897
+Cyproconazole 94361-06-5 single chemical entity Component is identical to the substance Cyproconazole 94361-06-5 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Cyproconazole C15H18ClN3O ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1 InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: Ireland Cyproconazole 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole 25Nov2010 2010 doi:10.2903/j.efsa.2010.1897
+Cyproconazole 94361-06-5 single chemical entity Component is identical to the substance Cyproconazole 94361-06-5 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Cyproconazole C15H18ClN3O ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1 InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: Ireland Cyproconazole 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole 25Nov2010 2010 doi:10.2903/j.efsa.2010.1897
+Cyproconazole 94361-06-5 single chemical entity Component is identical to the substance Cyproconazole 94361-06-5 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Cyproconazole C15H18ClN3O ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1 InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3 organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Ireland Cyproconazole 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole 25Nov2010 2010 doi:10.2903/j.efsa.2010.1897
+Cyproconazole 94361-06-5 single chemical entity Component is identical to the substance Cyproconazole 94361-06-5 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Cyproconazole C15H18ClN3O ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1 InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3 organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Hamster (as animal) embryo cells Not reported yes, concurrent vehicle without Negative RMS: Ireland Cyproconazole 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole 25Nov2010 2010 doi:10.2903/j.efsa.2010.1897
+Cyproconazole 94361-06-5 single chemical entity Component is identical to the substance Cyproconazole 94361-06-5 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Cyproconazole C15H18ClN3O ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1 InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Swiss 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect-toxicokinetic investigations RMS: Ireland Cyproconazole 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole 25Nov2010 2010 doi:10.2903/j.efsa.2010.1897
+Cyproconazole 94361-06-5 single chemical entity Component is identical to the substance Cyproconazole 94361-06-5 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Cyproconazole C15H18ClN3O ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1 InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Swiss 10 Male/Female oral: gavage 72.0000000000 h yes, concurrent vehicle not applicable Negative indirect-toxicokinetic investigations RMS: Ireland Cyproconazole 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole 25Nov2010 2010 doi:10.2903/j.efsa.2010.1897
+Cyproconazole 94361-06-5 single chemical entity Component is identical to the substance Cyproconazole 94361-06-5 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Cyproconazole C15H18ClN3O ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1 InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Swiss 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect-toxicokinetic investigations RMS: Ireland Cyproconazole 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole 25Nov2010 2010 doi:10.2903/j.efsa.2010.1897
+Cyproconazole 94361-06-5 single chemical entity Component is identical to the substance Cyproconazole 94361-06-5 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Cyproconazole C15H18ClN3O ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1 InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Ireland Cyproconazole 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole 25Nov2010 2010 doi:10.2903/j.efsa.2010.1897
+Cyproconazole 94361-06-5 single chemical entity Component is identical to the substance Cyproconazole 94361-06-5 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Cyproconazole C15H18ClN3O ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1 InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 16.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Ireland Cyproconazole 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole 25Nov2010 2010 doi:10.2903/j.efsa.2010.1897
+Cyproconazole 94361-06-5 single chemical entity Component is identical to the substance Cyproconazole 94361-06-5 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Cyproconazole C15H18ClN3O ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1 InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Ireland Cyproconazole 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole 25Nov2010 2010 doi:10.2903/j.efsa.2010.1897
+Cyproconazole 94361-06-5 single chemical entity Component is identical to the substance Cyproconazole 94361-06-5 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Cyproconazole C15H18ClN3O ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1 InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3 organic compound Other Other chromosome aberration dominant lethal assay in vivo According to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) No Acceptable Rat (as animal) Sprague-Dawley 20 Male oral: gavage 5.0000000000 D yes not applicable Negative RMS: Ireland Cyproconazole 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole 25Nov2010 2010 doi:10.2903/j.efsa.2010.1897
+Cyproconazole 94361-06-5 single chemical entity Component is a metabolite of the substance 5-(4-chlorophenyl)-5-hydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)-2-hexanoic acid (2E)-5-(4-chlorophenyl)-5-hydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)hex-2-enoic acid Not in list C15H16ClN3O3 OC(Cn1cncn1)(C(C)/C=C/C(=O)O)c2ccc(Cl)cc2 InChI=1/C15H16ClN3O3/c1-11(2-7-14(20)21)15(22,8-19-10-17-9-18-19)12-3-5-13(16)6-4-12/h2-7,9-11,22H,8H2,1H3,(H,20,21)/b7-2+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Ireland Cyproconazole 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole 25Nov2010 2010 doi:10.2903/j.efsa.2010.1897
+Cyproconazole 94361-06-5 single chemical entity Component is a metabolite of the substance 5-(4-chlorophenyl)-5-hydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)-2-hexanoic acid (2E)-5-(4-chlorophenyl)-5-hydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)hex-2-enoic acid Not in list C15H16ClN3O3 OC(Cn1cncn1)(C(C)/C=C/C(=O)O)c2ccc(Cl)cc2 InChI=1/C15H16ClN3O3/c1-11(2-7-14(20)21)15(22,8-19-10-17-9-18-19)12-3-5-13(16)6-4-12/h2-7,9-11,22H,8H2,1H3,(H,20,21)/b7-2+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Ireland Cyproconazole 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole 25Nov2010 2010 doi:10.2903/j.efsa.2010.1897
+Cyproconazole 94361-06-5 single chemical entity Component is a metabolite of the substance 5-(4-chlorophenyl)-5-hydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)-2-hexanoic acid (2E)-5-(4-chlorophenyl)-5-hydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)hex-2-enoic acid Not in list C15H16ClN3O3 OC(Cn1cncn1)(C(C)/C=C/C(=O)O)c2ccc(Cl)cc2 InChI=1/C15H16ClN3O3/c1-11(2-7-14(20)21)15(22,8-19-10-17-9-18-19)12-3-5-13(16)6-4-12/h2-7,9-11,22H,8H2,1H3,(H,20,21)/b7-2+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Ireland Cyproconazole 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole 25Nov2010 2010 doi:10.2903/j.efsa.2010.1897
+Cyproconazole 94361-06-5 single chemical entity Component is a metabolite of the substance 5-(4-chlorophenyl)-5-hydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)-2-hexanoic acid (2E)-5-(4-chlorophenyl)-5-hydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)hex-2-enoic acid Not in list C15H16ClN3O3 OC(Cn1cncn1)(C(C)/C=C/C(=O)O)c2ccc(Cl)cc2 InChI=1/C15H16ClN3O3/c1-11(2-7-14(20)21)15(22,8-19-10-17-9-18-19)12-3-5-13(16)6-4-12/h2-7,9-11,22H,8H2,1H3,(H,20,21)/b7-2+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Ireland Cyproconazole 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole 25Nov2010 2010 doi:10.2903/j.efsa.2010.1897
+Cyproconazole 94361-06-5 single chemical entity Component is a metabolite of the substance 5-(4-chlorophenyl)-5-hydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)-2-hexanoic acid (2E)-5-(4-chlorophenyl)-5-hydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)hex-2-enoic acid Not in list C15H16ClN3O3 OC(Cn1cncn1)(C(C)/C=C/C(=O)O)c2ccc(Cl)cc2 InChI=1/C15H16ClN3O3/c1-11(2-7-14(20)21)15(22,8-19-10-17-9-18-19)12-3-5-13(16)6-4-12/h2-7,9-11,22H,8H2,1H3,(H,20,21)/b7-2+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Ireland Cyproconazole 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole 25Nov2010 2010 doi:10.2903/j.efsa.2010.1897
+Cyproconazole 94361-06-5 single chemical entity Component is a metabolite of the substance 5-(4-chlorophenyl)-5-hydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)-2-hexanoic acid (2E)-5-(4-chlorophenyl)-5-hydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)hex-2-enoic acid Not in list C15H16ClN3O3 OC(Cn1cncn1)(C(C)/C=C/C(=O)O)c2ccc(Cl)cc2 InChI=1/C15H16ClN3O3/c1-11(2-7-14(20)21)15(22,8-19-10-17-9-18-19)12-3-5-13(16)6-4-12/h2-7,9-11,22H,8H2,1H3,(H,20,21)/b7-2+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Ireland Cyproconazole 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole 25Nov2010 2010 doi:10.2903/j.efsa.2010.1897
+Cyproconazole 94361-06-5 single chemical entity Component is a metabolite of the substance 5-(4-chlorophenyl)-5-hydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)-2-hexanoic acid (2E)-5-(4-chlorophenyl)-5-hydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)hex-2-enoic acid Not in list C15H16ClN3O3 OC(Cn1cncn1)(C(C)/C=C/C(=O)O)c2ccc(Cl)cc2 InChI=1/C15H16ClN3O3/c1-11(2-7-14(20)21)15(22,8-19-10-17-9-18-19)12-3-5-13(16)6-4-12/h2-7,9-11,22H,8H2,1H3,(H,20,21)/b7-2+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Ireland Cyproconazole 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole 25Nov2010 2010 doi:10.2903/j.efsa.2010.1897
+Cyproconazole 94361-06-5 single chemical entity Component is a metabolite of the substance 5-(4-chlorophenyl)-5-hydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)-2-hexanoic acid (2E)-5-(4-chlorophenyl)-5-hydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)hex-2-enoic acid Not in list C15H16ClN3O3 OC(Cn1cncn1)(C(C)/C=C/C(=O)O)c2ccc(Cl)cc2 InChI=1/C15H16ClN3O3/c1-11(2-7-14(20)21)15(22,8-19-10-17-9-18-19)12-3-5-13(16)6-4-12/h2-7,9-11,22H,8H2,1H3,(H,20,21)/b7-2+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Ireland Cyproconazole 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole 25Nov2010 2010 doi:10.2903/j.efsa.2010.1897
+Cyproconazole 94361-06-5 single chemical entity Component is a metabolite of the substance 5-(4-chlorophenyl)-5-hydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)-2-hexanoic acid (2E)-5-(4-chlorophenyl)-5-hydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)hex-2-enoic acid Not in list C15H16ClN3O3 OC(Cn1cncn1)(C(C)/C=C/C(=O)O)c2ccc(Cl)cc2 InChI=1/C15H16ClN3O3/c1-11(2-7-14(20)21)15(22,8-19-10-17-9-18-19)12-3-5-13(16)6-4-12/h2-7,9-11,22H,8H2,1H3,(H,20,21)/b7-2+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Ireland Cyproconazole 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole 25Nov2010 2010 doi:10.2903/j.efsa.2010.1897
+Cyproconazole 94361-06-5 single chemical entity Component is a metabolite of the substance 5-(4-chlorophenyl)-5-hydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)-2-hexanoic acid (2E)-5-(4-chlorophenyl)-5-hydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)hex-2-enoic acid Not in list C15H16ClN3O3 OC(Cn1cncn1)(C(C)/C=C/C(=O)O)c2ccc(Cl)cc2 InChI=1/C15H16ClN3O3/c1-11(2-7-14(20)21)15(22,8-19-10-17-9-18-19)12-3-5-13(16)6-4-12/h2-7,9-11,22H,8H2,1H3,(H,20,21)/b7-2+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Ireland Cyproconazole 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole 25Nov2010 2010 doi:10.2903/j.efsa.2010.1897
+Cyproconazole 94361-06-5 single chemical entity Component is a metabolite of the substance 5-(4-chloro-phenyl)-3,5-dihydroxy-4-methyl-6-[1,2,4]triazol-1-yl-hexanoic acid 5-(4-chlorophenyl)-3,5-dihydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)hexanoic acid Not in list C15H18ClN3O4 OC(Cn1cncn1)(C(C)C(O)CC(=O)O)c2ccc(Cl)cc2 InChI=1/C15H18ClN3O4/c1-10(13(20)6-14(21)22)15(23,7-19-9-17-8-18-19)11-2-4-12(16)5-3-11/h2-5,8-10,13,20,23H,6-7H2,1H3,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Ireland Cyproconazole 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole 25Nov2010 2010 doi:10.2903/j.efsa.2010.1897
+Cyproconazole 94361-06-5 single chemical entity Component is a metabolite of the substance 5-(4-chloro-phenyl)-3,5-dihydroxy-4-methyl-6-[1,2,4]triazol-1-yl-hexanoic acid 5-(4-chlorophenyl)-3,5-dihydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)hexanoic acid Not in list C15H18ClN3O4 OC(Cn1cncn1)(C(C)C(O)CC(=O)O)c2ccc(Cl)cc2 InChI=1/C15H18ClN3O4/c1-10(13(20)6-14(21)22)15(23,7-19-9-17-8-18-19)11-2-4-12(16)5-3-11/h2-5,8-10,13,20,23H,6-7H2,1H3,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Ireland Cyproconazole 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole 25Nov2010 2010 doi:10.2903/j.efsa.2010.1897
+Cyproconazole 94361-06-5 single chemical entity Component is a metabolite of the substance 5-(4-chloro-phenyl)-3,5-dihydroxy-4-methyl-6-[1,2,4]triazol-1-yl-hexanoic acid 5-(4-chlorophenyl)-3,5-dihydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)hexanoic acid Not in list C15H18ClN3O4 OC(Cn1cncn1)(C(C)C(O)CC(=O)O)c2ccc(Cl)cc2 InChI=1/C15H18ClN3O4/c1-10(13(20)6-14(21)22)15(23,7-19-9-17-8-18-19)11-2-4-12(16)5-3-11/h2-5,8-10,13,20,23H,6-7H2,1H3,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Ireland Cyproconazole 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole 25Nov2010 2010 doi:10.2903/j.efsa.2010.1897
+Cyproconazole 94361-06-5 single chemical entity Component is a metabolite of the substance 5-(4-chloro-phenyl)-3,5-dihydroxy-4-methyl-6-[1,2,4]triazol-1-yl-hexanoic acid 5-(4-chlorophenyl)-3,5-dihydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)hexanoic acid Not in list C15H18ClN3O4 OC(Cn1cncn1)(C(C)C(O)CC(=O)O)c2ccc(Cl)cc2 InChI=1/C15H18ClN3O4/c1-10(13(20)6-14(21)22)15(23,7-19-9-17-8-18-19)11-2-4-12(16)5-3-11/h2-5,8-10,13,20,23H,6-7H2,1H3,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Ireland Cyproconazole 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole 25Nov2010 2010 doi:10.2903/j.efsa.2010.1897
+Cyproconazole 94361-06-5 single chemical entity Component is a metabolite of the substance 5-(4-chloro-phenyl)-3,5-dihydroxy-4-methyl-6-[1,2,4]triazol-1-yl-hexanoic acid 5-(4-chlorophenyl)-3,5-dihydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)hexanoic acid Not in list C15H18ClN3O4 OC(Cn1cncn1)(C(C)C(O)CC(=O)O)c2ccc(Cl)cc2 InChI=1/C15H18ClN3O4/c1-10(13(20)6-14(21)22)15(23,7-19-9-17-8-18-19)11-2-4-12(16)5-3-11/h2-5,8-10,13,20,23H,6-7H2,1H3,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Ireland Cyproconazole 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole 25Nov2010 2010 doi:10.2903/j.efsa.2010.1897
+Cyproconazole 94361-06-5 single chemical entity Component is a metabolite of the substance 5-(4-chloro-phenyl)-3,5-dihydroxy-4-methyl-6-[1,2,4]triazol-1-yl-hexanoic acid 5-(4-chlorophenyl)-3,5-dihydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)hexanoic acid Not in list C15H18ClN3O4 OC(Cn1cncn1)(C(C)C(O)CC(=O)O)c2ccc(Cl)cc2 InChI=1/C15H18ClN3O4/c1-10(13(20)6-14(21)22)15(23,7-19-9-17-8-18-19)11-2-4-12(16)5-3-11/h2-5,8-10,13,20,23H,6-7H2,1H3,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Ireland Cyproconazole 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole 25Nov2010 2010 doi:10.2903/j.efsa.2010.1897
+Cyproconazole 94361-06-5 single chemical entity Component is a metabolite of the substance 5-(4-chloro-phenyl)-3,5-dihydroxy-4-methyl-6-[1,2,4]triazol-1-yl-hexanoic acid 5-(4-chlorophenyl)-3,5-dihydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)hexanoic acid Not in list C15H18ClN3O4 OC(Cn1cncn1)(C(C)C(O)CC(=O)O)c2ccc(Cl)cc2 InChI=1/C15H18ClN3O4/c1-10(13(20)6-14(21)22)15(23,7-19-9-17-8-18-19)11-2-4-12(16)5-3-11/h2-5,8-10,13,20,23H,6-7H2,1H3,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Ireland Cyproconazole 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole 25Nov2010 2010 doi:10.2903/j.efsa.2010.1897
+Cyproconazole 94361-06-5 single chemical entity Component is a metabolite of the substance 5-(4-chloro-phenyl)-3,5-dihydroxy-4-methyl-6-[1,2,4]triazol-1-yl-hexanoic acid 5-(4-chlorophenyl)-3,5-dihydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)hexanoic acid Not in list C15H18ClN3O4 OC(Cn1cncn1)(C(C)C(O)CC(=O)O)c2ccc(Cl)cc2 InChI=1/C15H18ClN3O4/c1-10(13(20)6-14(21)22)15(23,7-19-9-17-8-18-19)11-2-4-12(16)5-3-11/h2-5,8-10,13,20,23H,6-7H2,1H3,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Ireland Cyproconazole 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole 25Nov2010 2010 doi:10.2903/j.efsa.2010.1897
+Cyproconazole 94361-06-5 single chemical entity Component is a metabolite of the substance 5-(4-chloro-phenyl)-3,5-dihydroxy-4-methyl-6-[1,2,4]triazol-1-yl-hexanoic acid 5-(4-chlorophenyl)-3,5-dihydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)hexanoic acid Not in list C15H18ClN3O4 OC(Cn1cncn1)(C(C)C(O)CC(=O)O)c2ccc(Cl)cc2 InChI=1/C15H18ClN3O4/c1-10(13(20)6-14(21)22)15(23,7-19-9-17-8-18-19)11-2-4-12(16)5-3-11/h2-5,8-10,13,20,23H,6-7H2,1H3,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Ireland Cyproconazole 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole 25Nov2010 2010 doi:10.2903/j.efsa.2010.1897
+Cyproconazole 94361-06-5 single chemical entity Component is a metabolite of the substance 5-(4-chloro-phenyl)-3,5-dihydroxy-4-methyl-6-[1,2,4]triazol-1-yl-hexanoic acid 5-(4-chlorophenyl)-3,5-dihydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)hexanoic acid Not in list C15H18ClN3O4 OC(Cn1cncn1)(C(C)C(O)CC(=O)O)c2ccc(Cl)cc2 InChI=1/C15H18ClN3O4/c1-10(13(20)6-14(21)22)15(23,7-19-9-17-8-18-19)11-2-4-12(16)5-3-11/h2-5,8-10,13,20,23H,6-7H2,1H3,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Ireland Cyproconazole 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole 25Nov2010 2010 doi:10.2903/j.efsa.2010.1897
+Cyproconazole 94361-06-5 single chemical entity Component is a metabolite of the substance 5-(4-chloro-phenyl)-3,5-dihydroxy-4-methyl-6-[1,2,4]triazol-1-yl-hexanoic acid 5-(4-chlorophenyl)-3,5-dihydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)hexanoic acid Not in list C15H18ClN3O4 OC(Cn1cncn1)(C(C)C(O)CC(=O)O)c2ccc(Cl)cc2 InChI=1/C15H18ClN3O4/c1-10(13(20)6-14(21)22)15(23,7-19-9-17-8-18-19)11-2-4-12(16)5-3-11/h2-5,8-10,13,20,23H,6-7H2,1H3,(H,21,22) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative no information RMS: Ireland Cyproconazole 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole 25Nov2010 2010 doi:10.2903/j.efsa.2010.1897
+Cyproconazole 94361-06-5 single chemical entity Component is a metabolite of the substance 5-(4-chloro-phenyl)-3,5-dihydroxy-4-methyl-6-[1,2,4]triazol-1-yl-hexanoic acid 5-(4-chlorophenyl)-3,5-dihydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)hexanoic acid Not in list C15H18ClN3O4 OC(Cn1cncn1)(C(C)C(O)CC(=O)O)c2ccc(Cl)cc2 InChI=1/C15H18ClN3O4/c1-10(13(20)6-14(21)22)15(23,7-19-9-17-8-18-19)11-2-4-12(16)5-3-11/h2-5,8-10,13,20,23H,6-7H2,1H3,(H,21,22) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Negative no information RMS: Ireland Cyproconazole 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole 25Nov2010 2010 doi:10.2903/j.efsa.2010.1897
+Cyproconazole 94361-06-5 single chemical entity Component is a metabolite of the substance 5-(4-chloro-phenyl)-3,5-dihydroxy-4-methyl-6-[1,2,4]triazol-1-yl-hexanoic acid 5-(4-chlorophenyl)-3,5-dihydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)hexanoic acid Not in list C15H18ClN3O4 OC(Cn1cncn1)(C(C)C(O)CC(=O)O)c2ccc(Cl)cc2 InChI=1/C15H18ClN3O4/c1-10(13(20)6-14(21)22)15(23,7-19-9-17-8-18-19)11-2-4-12(16)5-3-11/h2-5,8-10,13,20,23H,6-7H2,1H3,(H,21,22) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Negative RMS: Ireland Cyproconazole 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole 25Nov2010 2010 doi:10.2903/j.efsa.2010.1897
+Cyproconazole 94361-06-5 single chemical entity Component is a metabolite of the substance 5-(4-chloro-phenyl)-3,5-dihydroxy-4-methyl-6-[1,2,4]triazol-1-yl-hexanoic acid 5-(4-chlorophenyl)-3,5-dihydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)hexanoic acid Not in list C15H18ClN3O4 OC(Cn1cncn1)(C(C)C(O)CC(=O)O)c2ccc(Cl)cc2 InChI=1/C15H18ClN3O4/c1-10(13(20)6-14(21)22)15(23,7-19-9-17-8-18-19)11-2-4-12(16)5-3-11/h2-5,8-10,13,20,23H,6-7H2,1H3,(H,21,22) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Positive RMS: Ireland Cyproconazole 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole 25Nov2010 2010 doi:10.2903/j.efsa.2010.1897
+Cyproconazole 94361-06-5 single chemical entity Component is identical to the substance Cyproconazole 94361-06-5 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Cyproconazole C15H18ClN3O ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1 InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes with Negative RMS: Ireland Cyproconazole (Addendum to the Draft Report and Proposed Decision) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole 25Nov2010 2010 doi:10.2903/j.efsa.2010.1897
+Cyproconazole 94361-06-5 single chemical entity Component is identical to the substance Cyproconazole 94361-06-5 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Cyproconazole C15H18ClN3O ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1 InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes without Negative RMS: Ireland Cyproconazole (Addendum to the Draft Report and Proposed Decision) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole 25Nov2010 2010 doi:10.2903/j.efsa.2010.1897
+Cyproconazole 94361-06-5 single chemical entity Component is identical to the substance Cyproconazole 94361-06-5 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Cyproconazole C15H18ClN3O ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1 InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Ireland Cyproconazole (Addendum to the Draft Report and Proposed Decision) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole 25Nov2010 2010 doi:10.2903/j.efsa.2010.1897
+Cyproconazole 94361-06-5 single chemical entity Component is identical to the substance Cyproconazole 94361-06-5 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Cyproconazole C15H18ClN3O ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1 InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes without Negative RMS: Ireland Cyproconazole (Addendum to the Draft Report and Proposed Decision) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole 25Nov2010 2010 doi:10.2903/j.efsa.2010.1897
+Cyproconazole 94361-06-5 single chemical entity Component is identical to the substance Cyproconazole 94361-06-5 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Cyproconazole C15H18ClN3O ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1 InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Ireland Cyproconazole (Addendum to the Draft Report and Proposed Decision) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole 25Nov2010 2010 doi:10.2903/j.efsa.2010.1897
+Cyproconazole 94361-06-5 single chemical entity Component is identical to the substance Cyproconazole 94361-06-5 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Cyproconazole C15H18ClN3O ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1 InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Ireland Cyproconazole (Addendum to the Draft Report and Proposed Decision) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole 25Nov2010 2010 doi:10.2903/j.efsa.2010.1897
+Cyproconazole 94361-06-5 single chemical entity Component is identical to the substance Cyproconazole 94361-06-5 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Cyproconazole C15H18ClN3O ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1 InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Ireland Cyproconazole (Addendum to the Draft Report and Proposed Decision) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole 25Nov2010 2010 doi:10.2903/j.efsa.2010.1897
+Cyproconazole 94361-06-5 single chemical entity Component is identical to the substance Cyproconazole 94361-06-5 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Cyproconazole C15H18ClN3O ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1 InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Ireland Cyproconazole (Addendum to the Draft Report and Proposed Decision) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole 25Nov2010 2010 doi:10.2903/j.efsa.2010.1897
+Cyproconazole 94361-06-5 single chemical entity Component is identical to the substance Cyproconazole 94361-06-5 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Cyproconazole C15H18ClN3O ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1 InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes with Negative RMS: Ireland Cyproconazole (Addendum to the Draft Report and Proposed Decision) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole 25Nov2010 2010 doi:10.2903/j.efsa.2010.1897
+Cyproconazole 94361-06-5 single chemical entity Component is identical to the substance Cyproconazole 94361-06-5 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Cyproconazole C15H18ClN3O ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1 InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Ireland Cyproconazole (Addendum to the Draft Report and Proposed Decision) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole 25Nov2010 2010 doi:10.2903/j.efsa.2010.1897
+Cyproconazole 94361-06-5 single chemical entity Component is identical to the substance Cyproconazole 94361-06-5 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Cyproconazole C15H18ClN3O ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1 InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Ireland Cyproconazole (Addendum to the Draft Report and Proposed Decision) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole 25Nov2010 2010 doi:10.2903/j.efsa.2010.1897
+Cyproconazole 94361-06-5 single chemical entity Component is identical to the substance Cyproconazole 94361-06-5 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Cyproconazole C15H18ClN3O ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1 InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Ireland Cyproconazole (Addendum to the Draft Report and Proposed Decision) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole 25Nov2010 2010 doi:10.2903/j.efsa.2010.1897
+Cyprodinil 121552-61-2 single chemical entity Component is identical to the substance Cyprodinil 121552-61-2 4-cyclopropyl-6-methyl-N-phenylpyrimidin-2-amine Cyprodinil C14H15N3 CC1=NC(NC3=CC=CC=C3)=NC(C2CC2)=C1 InChI=1S/C14H15N3/c1-10-9-13(11-7-8-11)17-14(15-10)16-12-5-3-2-4-6-12/h2-6,9,11H,7-8H2,1H3,(H,15,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is identical to the substance Cyprodinil 121552-61-2 4-cyclopropyl-6-methyl-N-phenylpyrimidin-2-amine Cyprodinil C14H15N3 CC1=NC(NC3=CC=CC=C3)=NC(C2CC2)=C1 InChI=1S/C14H15N3/c1-10-9-13(11-7-8-11)17-14(15-10)16-12-5-3-2-4-6-12/h2-6,9,11H,7-8H2,1H3,(H,15,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is identical to the substance Cyprodinil 121552-61-2 4-cyclopropyl-6-methyl-N-phenylpyrimidin-2-amine Cyprodinil C14H15N3 CC1=NC(NC3=CC=CC=C3)=NC(C2CC2)=C1 InChI=1S/C14H15N3/c1-10-9-13(11-7-8-11)17-14(15-10)16-12-5-3-2-4-6-12/h2-6,9,11H,7-8H2,1H3,(H,15,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is identical to the substance Cyprodinil 121552-61-2 4-cyclopropyl-6-methyl-N-phenylpyrimidin-2-amine Cyprodinil C14H15N3 CC1=NC(NC3=CC=CC=C3)=NC(C2CC2)=C1 InChI=1S/C14H15N3/c1-10-9-13(11-7-8-11)17-14(15-10)16-12-5-3-2-4-6-12/h2-6,9,11H,7-8H2,1H3,(H,15,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is identical to the substance Cyprodinil 121552-61-2 4-cyclopropyl-6-methyl-N-phenylpyrimidin-2-amine Cyprodinil C14H15N3 CC1=NC(NC3=CC=CC=C3)=NC(C2CC2)=C1 InChI=1S/C14H15N3/c1-10-9-13(11-7-8-11)17-14(15-10)16-12-5-3-2-4-6-12/h2-6,9,11H,7-8H2,1H3,(H,15,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is identical to the substance Cyprodinil 121552-61-2 4-cyclopropyl-6-methyl-N-phenylpyrimidin-2-amine Cyprodinil C14H15N3 CC1=NC(NC3=CC=CC=C3)=NC(C2CC2)=C1 InChI=1S/C14H15N3/c1-10-9-13(11-7-8-11)17-14(15-10)16-12-5-3-2-4-6-12/h2-6,9,11H,7-8H2,1H3,(H,15,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is identical to the substance Cyprodinil 121552-61-2 4-cyclopropyl-6-methyl-N-phenylpyrimidin-2-amine Cyprodinil C14H15N3 CC1=NC(NC3=CC=CC=C3)=NC(C2CC2)=C1 InChI=1S/C14H15N3/c1-10-9-13(11-7-8-11)17-14(15-10)16-12-5-3-2-4-6-12/h2-6,9,11H,7-8H2,1H3,(H,15,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is identical to the substance Cyprodinil 121552-61-2 4-cyclopropyl-6-methyl-N-phenylpyrimidin-2-amine Cyprodinil C14H15N3 CC1=NC(NC3=CC=CC=C3)=NC(C2CC2)=C1 InChI=1S/C14H15N3/c1-10-9-13(11-7-8-11)17-14(15-10)16-12-5-3-2-4-6-12/h2-6,9,11H,7-8H2,1H3,(H,15,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is identical to the substance Cyprodinil 121552-61-2 4-cyclopropyl-6-methyl-N-phenylpyrimidin-2-amine Cyprodinil C14H15N3 CC1=NC(NC3=CC=CC=C3)=NC(C2CC2)=C1 InChI=1S/C14H15N3/c1-10-9-13(11-7-8-11)17-14(15-10)16-12-5-3-2-4-6-12/h2-6,9,11H,7-8H2,1H3,(H,15,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is identical to the substance Cyprodinil 121552-61-2 4-cyclopropyl-6-methyl-N-phenylpyrimidin-2-amine Cyprodinil C14H15N3 CC1=NC(NC3=CC=CC=C3)=NC(C2CC2)=C1 InChI=1S/C14H15N3/c1-10-9-13(11-7-8-11)17-14(15-10)16-12-5-3-2-4-6-12/h2-6,9,11H,7-8H2,1H3,(H,15,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is identical to the substance Cyprodinil 121552-61-2 4-cyclopropyl-6-methyl-N-phenylpyrimidin-2-amine Cyprodinil C14H15N3 CC1=NC(NC3=CC=CC=C3)=NC(C2CC2)=C1 InChI=1S/C14H15N3/c1-10-9-13(11-7-8-11)17-14(15-10)16-12-5-3-2-4-6-12/h2-6,9,11H,7-8H2,1H3,(H,15,16,17) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is identical to the substance Cyprodinil 121552-61-2 4-cyclopropyl-6-methyl-N-phenylpyrimidin-2-amine Cyprodinil C14H15N3 CC1=NC(NC3=CC=CC=C3)=NC(C2CC2)=C1 InChI=1S/C14H15N3/c1-10-9-13(11-7-8-11)17-14(15-10)16-12-5-3-2-4-6-12/h2-6,9,11H,7-8H2,1H3,(H,15,16,17) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is identical to the substance Cyprodinil 121552-61-2 4-cyclopropyl-6-methyl-N-phenylpyrimidin-2-amine Cyprodinil C14H15N3 CC1=NC(NC3=CC=CC=C3)=NC(C2CC2)=C1 InChI=1S/C14H15N3/c1-10-9-13(11-7-8-11)17-14(15-10)16-12-5-3-2-4-6-12/h2-6,9,11H,7-8H2,1H3,(H,15,16,17) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is identical to the substance Cyprodinil 121552-61-2 4-cyclopropyl-6-methyl-N-phenylpyrimidin-2-amine Cyprodinil C14H15N3 CC1=NC(NC3=CC=CC=C3)=NC(C2CC2)=C1 InChI=1S/C14H15N3/c1-10-9-13(11-7-8-11)17-14(15-10)16-12-5-3-2-4-6-12/h2-6,9,11H,7-8H2,1H3,(H,15,16,17) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is identical to the substance Cyprodinil 121552-61-2 4-cyclopropyl-6-methyl-N-phenylpyrimidin-2-amine Cyprodinil C14H15N3 CC1=NC(NC3=CC=CC=C3)=NC(C2CC2)=C1 InChI=1S/C14H15N3/c1-10-9-13(11-7-8-11)17-14(15-10)16-12-5-3-2-4-6-12/h2-6,9,11H,7-8H2,1H3,(H,15,16,17) organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is identical to the substance Cyprodinil 121552-61-2 4-cyclopropyl-6-methyl-N-phenylpyrimidin-2-amine Cyprodinil C14H15N3 CC1=NC(NC3=CC=CC=C3)=NC(C2CC2)=C1 InChI=1S/C14H15N3/c1-10-9-13(11-7-8-11)17-14(15-10)16-12-5-3-2-4-6-12/h2-6,9,11H,7-8H2,1H3,(H,15,16,17) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Not reported 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is identical to the substance Cyprodinil 121552-61-2 4-cyclopropyl-6-methyl-N-phenylpyrimidin-2-amine Cyprodinil C14H15N3 CC1=NC(NC3=CC=CC=C3)=NC(C2CC2)=C1 InChI=1S/C14H15N3/c1-10-9-13(11-7-8-11)17-14(15-10)16-12-5-3-2-4-6-12/h2-6,9,11H,7-8H2,1H3,(H,15,16,17) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Not reported 10 Male/Female oral: gavage 16.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is identical to the substance Cyprodinil 121552-61-2 4-cyclopropyl-6-methyl-N-phenylpyrimidin-2-amine Cyprodinil C14H15N3 CC1=NC(NC3=CC=CC=C3)=NC(C2CC2)=C1 InChI=1S/C14H15N3/c1-10-9-13(11-7-8-11)17-14(15-10)16-12-5-3-2-4-6-12/h2-6,9,11H,7-8H2,1H3,(H,15,16,17) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Not reported 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is a metabolite of the substance 4-cyclopropyl-6-methyl-pyrimidine-2-ylamine 92238-61-4 4-cyclopropyl-6-methylpyrimidin-2-amine Not in list C8H11N3 CC1=NC(=NC(=C1)C2CC2)N InChI=1S/C8H11N3/c1-5-4-7(6-2-3-6)11-8(9)10-5/h4,6H,2-3H2,1H3,(H2,9,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is a metabolite of the substance 4-cyclopropyl-6-methyl-pyrimidine-2-ylamine 92238-61-4 4-cyclopropyl-6-methylpyrimidin-2-amine Not in list C8H11N3 CC1=NC(=NC(=C1)C2CC2)N InChI=1S/C8H11N3/c1-5-4-7(6-2-3-6)11-8(9)10-5/h4,6H,2-3H2,1H3,(H2,9,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is a metabolite of the substance 4-cyclopropyl-6-methyl-pyrimidine-2-ylamine 92238-61-4 4-cyclopropyl-6-methylpyrimidin-2-amine Not in list C8H11N3 CC1=NC(=NC(=C1)C2CC2)N InChI=1S/C8H11N3/c1-5-4-7(6-2-3-6)11-8(9)10-5/h4,6H,2-3H2,1H3,(H2,9,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is a metabolite of the substance 4-cyclopropyl-6-methyl-pyrimidine-2-ylamine 92238-61-4 4-cyclopropyl-6-methylpyrimidin-2-amine Not in list C8H11N3 CC1=NC(=NC(=C1)C2CC2)N InChI=1S/C8H11N3/c1-5-4-7(6-2-3-6)11-8(9)10-5/h4,6H,2-3H2,1H3,(H2,9,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is a metabolite of the substance 4-cyclopropyl-6-methyl-pyrimidine-2-ylamine 92238-61-4 4-cyclopropyl-6-methylpyrimidin-2-amine Not in list C8H11N3 CC1=NC(=NC(=C1)C2CC2)N InChI=1S/C8H11N3/c1-5-4-7(6-2-3-6)11-8(9)10-5/h4,6H,2-3H2,1H3,(H2,9,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is a metabolite of the substance 4-cyclopropyl-6-methyl-pyrimidine-2-ylamine 92238-61-4 4-cyclopropyl-6-methylpyrimidin-2-amine Not in list C8H11N3 CC1=NC(=NC(=C1)C2CC2)N InChI=1S/C8H11N3/c1-5-4-7(6-2-3-6)11-8(9)10-5/h4,6H,2-3H2,1H3,(H2,9,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is a metabolite of the substance 4-cyclopropyl-6-methyl-pyrimidine-2-ylamine 92238-61-4 4-cyclopropyl-6-methylpyrimidin-2-amine Not in list C8H11N3 CC1=NC(=NC(=C1)C2CC2)N InChI=1S/C8H11N3/c1-5-4-7(6-2-3-6)11-8(9)10-5/h4,6H,2-3H2,1H3,(H2,9,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is a metabolite of the substance 4-cyclopropyl-6-methyl-pyrimidine-2-ylamine 92238-61-4 4-cyclopropyl-6-methylpyrimidin-2-amine Not in list C8H11N3 CC1=NC(=NC(=C1)C2CC2)N InChI=1S/C8H11N3/c1-5-4-7(6-2-3-6)11-8(9)10-5/h4,6H,2-3H2,1H3,(H2,9,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is a metabolite of the substance 4-cyclopropyl-6-methyl-pyrimidine-2-ylamine 92238-61-4 4-cyclopropyl-6-methylpyrimidin-2-amine Not in list C8H11N3 CC1=NC(=NC(=C1)C2CC2)N InChI=1S/C8H11N3/c1-5-4-7(6-2-3-6)11-8(9)10-5/h4,6H,2-3H2,1H3,(H2,9,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is a metabolite of the substance 4-cyclopropyl-6-methyl-pyrimidine-2-ylamine 92238-61-4 4-cyclopropyl-6-methylpyrimidin-2-amine Not in list C8H11N3 CC1=NC(=NC(=C1)C2CC2)N InChI=1S/C8H11N3/c1-5-4-7(6-2-3-6)11-8(9)10-5/h4,6H,2-3H2,1H3,(H2,9,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is a metabolite of the substance 4-cyclopropyl-6-methyl-pyrimidine-2-ylamine 92238-61-4 4-cyclopropyl-6-methylpyrimidin-2-amine Not in list C8H11N3 CC1=NC(=NC(=C1)C2CC2)N InChI=1S/C8H11N3/c1-5-4-7(6-2-3-6)11-8(9)10-5/h4,6H,2-3H2,1H3,(H2,9,10,11) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is a metabolite of the substance 4-cyclopropyl-6-methyl-pyrimidine-2-ylamine 92238-61-4 4-cyclopropyl-6-methylpyrimidin-2-amine Not in list C8H11N3 CC1=NC(=NC(=C1)C2CC2)N InChI=1S/C8H11N3/c1-5-4-7(6-2-3-6)11-8(9)10-5/h4,6H,2-3H2,1H3,(H2,9,10,11) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is a metabolite of the substance 4-cyclopropyl-6-methyl-pyrimidine-2-ylamine 92238-61-4 4-cyclopropyl-6-methylpyrimidin-2-amine Not in list C8H11N3 CC1=NC(=NC(=C1)C2CC2)N InChI=1S/C8H11N3/c1-5-4-7(6-2-3-6)11-8(9)10-5/h4,6H,2-3H2,1H3,(H2,9,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is a metabolite of the substance 4-cyclopropyl-6-methyl-pyrimidine-2-ylamine 92238-61-4 4-cyclopropyl-6-methylpyrimidin-2-amine Not in list C8H11N3 CC1=NC(=NC(=C1)C2CC2)N InChI=1S/C8H11N3/c1-5-4-7(6-2-3-6)11-8(9)10-5/h4,6H,2-3H2,1H3,(H2,9,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is a metabolite of the substance 3-(4-Cyclopropyl-6-methyl-pyrimidin-2-yl-amino)-phenol 3-[(4-cyclopropyl-6-methylpyrimidin-2-yl)amino]phenol Not in list Oc3cc(Nc1nc(C)cc(n1)C2CC2)ccc3 InChI=1S/C14H15N3O/c1-9-7-13(10-5-6-10)17-14(15-9)16-11-3-2-4-12(18)8-11/h2-4,7-8,10,18H,5-6H2,1H3,(H,15,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is a metabolite of the substance 3-(4-Cyclopropyl-6-methyl-pyrimidin-2-yl-amino)-phenol 3-[(4-cyclopropyl-6-methylpyrimidin-2-yl)amino]phenol Not in list Oc3cc(Nc1nc(C)cc(n1)C2CC2)ccc3 InChI=1S/C14H15N3O/c1-9-7-13(10-5-6-10)17-14(15-9)16-11-3-2-4-12(18)8-11/h2-4,7-8,10,18H,5-6H2,1H3,(H,15,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is a metabolite of the substance 3-(4-Cyclopropyl-6-methyl-pyrimidin-2-yl-amino)-phenol 3-[(4-cyclopropyl-6-methylpyrimidin-2-yl)amino]phenol Not in list Oc3cc(Nc1nc(C)cc(n1)C2CC2)ccc3 InChI=1S/C14H15N3O/c1-9-7-13(10-5-6-10)17-14(15-9)16-11-3-2-4-12(18)8-11/h2-4,7-8,10,18H,5-6H2,1H3,(H,15,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is a metabolite of the substance 3-(4-Cyclopropyl-6-methyl-pyrimidin-2-yl-amino)-phenol 3-[(4-cyclopropyl-6-methylpyrimidin-2-yl)amino]phenol Not in list Oc3cc(Nc1nc(C)cc(n1)C2CC2)ccc3 InChI=1S/C14H15N3O/c1-9-7-13(10-5-6-10)17-14(15-9)16-11-3-2-4-12(18)8-11/h2-4,7-8,10,18H,5-6H2,1H3,(H,15,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is a metabolite of the substance 3-(4-Cyclopropyl-6-methyl-pyrimidin-2-yl-amino)-phenol 3-[(4-cyclopropyl-6-methylpyrimidin-2-yl)amino]phenol Not in list Oc3cc(Nc1nc(C)cc(n1)C2CC2)ccc3 InChI=1S/C14H15N3O/c1-9-7-13(10-5-6-10)17-14(15-9)16-11-3-2-4-12(18)8-11/h2-4,7-8,10,18H,5-6H2,1H3,(H,15,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is a metabolite of the substance 3-(4-Cyclopropyl-6-methyl-pyrimidin-2-yl-amino)-phenol 3-[(4-cyclopropyl-6-methylpyrimidin-2-yl)amino]phenol Not in list Oc3cc(Nc1nc(C)cc(n1)C2CC2)ccc3 InChI=1S/C14H15N3O/c1-9-7-13(10-5-6-10)17-14(15-9)16-11-3-2-4-12(18)8-11/h2-4,7-8,10,18H,5-6H2,1H3,(H,15,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is a metabolite of the substance 3-(4-Cyclopropyl-6-methyl-pyrimidin-2-yl-amino)-phenol 3-[(4-cyclopropyl-6-methylpyrimidin-2-yl)amino]phenol Not in list Oc3cc(Nc1nc(C)cc(n1)C2CC2)ccc3 InChI=1S/C14H15N3O/c1-9-7-13(10-5-6-10)17-14(15-9)16-11-3-2-4-12(18)8-11/h2-4,7-8,10,18H,5-6H2,1H3,(H,15,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is a metabolite of the substance 3-(4-Cyclopropyl-6-methyl-pyrimidin-2-yl-amino)-phenol 3-[(4-cyclopropyl-6-methylpyrimidin-2-yl)amino]phenol Not in list Oc3cc(Nc1nc(C)cc(n1)C2CC2)ccc3 InChI=1S/C14H15N3O/c1-9-7-13(10-5-6-10)17-14(15-9)16-11-3-2-4-12(18)8-11/h2-4,7-8,10,18H,5-6H2,1H3,(H,15,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is a metabolite of the substance 3-(4-Cyclopropyl-6-methyl-pyrimidin-2-yl-amino)-phenol 3-[(4-cyclopropyl-6-methylpyrimidin-2-yl)amino]phenol Not in list Oc3cc(Nc1nc(C)cc(n1)C2CC2)ccc3 InChI=1S/C14H15N3O/c1-9-7-13(10-5-6-10)17-14(15-9)16-11-3-2-4-12(18)8-11/h2-4,7-8,10,18H,5-6H2,1H3,(H,15,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is a metabolite of the substance 3-(4-Cyclopropyl-6-methyl-pyrimidin-2-yl-amino)-phenol 3-[(4-cyclopropyl-6-methylpyrimidin-2-yl)amino]phenol Not in list Oc3cc(Nc1nc(C)cc(n1)C2CC2)ccc3 InChI=1S/C14H15N3O/c1-9-7-13(10-5-6-10)17-14(15-9)16-11-3-2-4-12(18)8-11/h2-4,7-8,10,18H,5-6H2,1H3,(H,15,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is a metabolite of the substance 3-(4-Cyclopropyl-6-methyl-pyrimidin-2-yl-amino)-phenol 3-[(4-cyclopropyl-6-methylpyrimidin-2-yl)amino]phenol Not in list Oc3cc(Nc1nc(C)cc(n1)C2CC2)ccc3 InChI=1S/C14H15N3O/c1-9-7-13(10-5-6-10)17-14(15-9)16-11-3-2-4-12(18)8-11/h2-4,7-8,10,18H,5-6H2,1H3,(H,15,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is a metabolite of the substance 3-(4-Cyclopropyl-6-methyl-pyrimidin-2-yl-amino)-phenol 3-[(4-cyclopropyl-6-methylpyrimidin-2-yl)amino]phenol Not in list Oc3cc(Nc1nc(C)cc(n1)C2CC2)ccc3 InChI=1S/C14H15N3O/c1-9-7-13(10-5-6-10)17-14(15-9)16-11-3-2-4-12(18)8-11/h2-4,7-8,10,18H,5-6H2,1H3,(H,15,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is a metabolite of the substance (2-Amino-6-cyclopropyl-pyrimidin-4-yl)-methanol (2-amino-6-cyclopropylpyrimidin-4-yl)methanol Not in list C8H11N3O Nc1nc(cc(CO)n1)C2CC2 InChI=1/C8H11N3O/c9-8-10-6(4-12)3-7(11-8)5-1-2-5/h3,5,12H,1-2,4H2,(H2,9,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is a metabolite of the substance (2-Amino-6-cyclopropyl-pyrimidin-4-yl)-methanol (2-amino-6-cyclopropylpyrimidin-4-yl)methanol Not in list C8H11N3O Nc1nc(cc(CO)n1)C2CC2 InChI=1/C8H11N3O/c9-8-10-6(4-12)3-7(11-8)5-1-2-5/h3,5,12H,1-2,4H2,(H2,9,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is a metabolite of the substance (2-Amino-6-cyclopropyl-pyrimidin-4-yl)-methanol (2-amino-6-cyclopropylpyrimidin-4-yl)methanol Not in list C8H11N3O Nc1nc(cc(CO)n1)C2CC2 InChI=1/C8H11N3O/c9-8-10-6(4-12)3-7(11-8)5-1-2-5/h3,5,12H,1-2,4H2,(H2,9,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is a metabolite of the substance (2-Amino-6-cyclopropyl-pyrimidin-4-yl)-methanol (2-amino-6-cyclopropylpyrimidin-4-yl)methanol Not in list C8H11N3O Nc1nc(cc(CO)n1)C2CC2 InChI=1/C8H11N3O/c9-8-10-6(4-12)3-7(11-8)5-1-2-5/h3,5,12H,1-2,4H2,(H2,9,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is a metabolite of the substance (2-Amino-6-cyclopropyl-pyrimidin-4-yl)-methanol (2-amino-6-cyclopropylpyrimidin-4-yl)methanol Not in list C8H11N3O Nc1nc(cc(CO)n1)C2CC2 InChI=1/C8H11N3O/c9-8-10-6(4-12)3-7(11-8)5-1-2-5/h3,5,12H,1-2,4H2,(H2,9,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is a metabolite of the substance (2-Amino-6-cyclopropyl-pyrimidin-4-yl)-methanol (2-amino-6-cyclopropylpyrimidin-4-yl)methanol Not in list C8H11N3O Nc1nc(cc(CO)n1)C2CC2 InChI=1/C8H11N3O/c9-8-10-6(4-12)3-7(11-8)5-1-2-5/h3,5,12H,1-2,4H2,(H2,9,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is a metabolite of the substance (2-Amino-6-cyclopropyl-pyrimidin-4-yl)-methanol (2-amino-6-cyclopropylpyrimidin-4-yl)methanol Not in list C8H11N3O Nc1nc(cc(CO)n1)C2CC2 InChI=1/C8H11N3O/c9-8-10-6(4-12)3-7(11-8)5-1-2-5/h3,5,12H,1-2,4H2,(H2,9,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is a metabolite of the substance (2-Amino-6-cyclopropyl-pyrimidin-4-yl)-methanol (2-amino-6-cyclopropylpyrimidin-4-yl)methanol Not in list C8H11N3O Nc1nc(cc(CO)n1)C2CC2 InChI=1/C8H11N3O/c9-8-10-6(4-12)3-7(11-8)5-1-2-5/h3,5,12H,1-2,4H2,(H2,9,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is a metabolite of the substance (2-Amino-6-cyclopropyl-pyrimidin-4-yl)-methanol (2-amino-6-cyclopropylpyrimidin-4-yl)methanol Not in list C8H11N3O Nc1nc(cc(CO)n1)C2CC2 InChI=1/C8H11N3O/c9-8-10-6(4-12)3-7(11-8)5-1-2-5/h3,5,12H,1-2,4H2,(H2,9,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is a metabolite of the substance (2-Amino-6-cyclopropyl-pyrimidin-4-yl)-methanol (2-amino-6-cyclopropylpyrimidin-4-yl)methanol Not in list C8H11N3O Nc1nc(cc(CO)n1)C2CC2 InChI=1/C8H11N3O/c9-8-10-6(4-12)3-7(11-8)5-1-2-5/h3,5,12H,1-2,4H2,(H2,9,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is a metabolite of the substance (2-Amino-6-cyclopropyl-pyrimidin-4-yl)-methanol (2-amino-6-cyclopropylpyrimidin-4-yl)methanol Not in list C8H11N3O Nc1nc(cc(CO)n1)C2CC2 InChI=1/C8H11N3O/c9-8-10-6(4-12)3-7(11-8)5-1-2-5/h3,5,12H,1-2,4H2,(H2,9,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is a metabolite of the substance (2-Amino-6-cyclopropyl-pyrimidin-4-yl)-methanol (2-amino-6-cyclopropylpyrimidin-4-yl)methanol Not in list C8H11N3O Nc1nc(cc(CO)n1)C2CC2 InChI=1/C8H11N3O/c9-8-10-6(4-12)3-7(11-8)5-1-2-5/h3,5,12H,1-2,4H2,(H2,9,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is a metabolite of the substance 4-Cyclopropyl-6-methyl-pyrimidin-2-ol 4-cyclopropyl-6-methylpyrimidin-2-ol Not in list C8H10N2O Cc1cc(nc(O)n1)C2CC2 InChI=1/C8H10N2O/c1-5-4-7(6-2-3-6)10-8(11)9-5/h4,6H,2-3H2,1H3,(H,9,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is a metabolite of the substance 4-Cyclopropyl-6-methyl-pyrimidin-2-ol 4-cyclopropyl-6-methylpyrimidin-2-ol Not in list C8H10N2O Cc1cc(nc(O)n1)C2CC2 InChI=1/C8H10N2O/c1-5-4-7(6-2-3-6)10-8(11)9-5/h4,6H,2-3H2,1H3,(H,9,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is a metabolite of the substance 4-Cyclopropyl-6-methyl-pyrimidin-2-ol 4-cyclopropyl-6-methylpyrimidin-2-ol Not in list C8H10N2O Cc1cc(nc(O)n1)C2CC2 InChI=1/C8H10N2O/c1-5-4-7(6-2-3-6)10-8(11)9-5/h4,6H,2-3H2,1H3,(H,9,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is a metabolite of the substance 4-Cyclopropyl-6-methyl-pyrimidin-2-ol 4-cyclopropyl-6-methylpyrimidin-2-ol Not in list C8H10N2O Cc1cc(nc(O)n1)C2CC2 InChI=1/C8H10N2O/c1-5-4-7(6-2-3-6)10-8(11)9-5/h4,6H,2-3H2,1H3,(H,9,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is a metabolite of the substance 4-Cyclopropyl-6-methyl-pyrimidin-2-ol 4-cyclopropyl-6-methylpyrimidin-2-ol Not in list C8H10N2O Cc1cc(nc(O)n1)C2CC2 InChI=1/C8H10N2O/c1-5-4-7(6-2-3-6)10-8(11)9-5/h4,6H,2-3H2,1H3,(H,9,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is a metabolite of the substance 4-Cyclopropyl-6-methyl-pyrimidin-2-ol 4-cyclopropyl-6-methylpyrimidin-2-ol Not in list C8H10N2O Cc1cc(nc(O)n1)C2CC2 InChI=1/C8H10N2O/c1-5-4-7(6-2-3-6)10-8(11)9-5/h4,6H,2-3H2,1H3,(H,9,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is a metabolite of the substance 4-Cyclopropyl-6-methyl-pyrimidin-2-ol 4-cyclopropyl-6-methylpyrimidin-2-ol Not in list C8H10N2O Cc1cc(nc(O)n1)C2CC2 InChI=1/C8H10N2O/c1-5-4-7(6-2-3-6)10-8(11)9-5/h4,6H,2-3H2,1H3,(H,9,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is a metabolite of the substance 4-Cyclopropyl-6-methyl-pyrimidin-2-ol 4-cyclopropyl-6-methylpyrimidin-2-ol Not in list C8H10N2O Cc1cc(nc(O)n1)C2CC2 InChI=1/C8H10N2O/c1-5-4-7(6-2-3-6)10-8(11)9-5/h4,6H,2-3H2,1H3,(H,9,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is a metabolite of the substance 4-Cyclopropyl-6-methyl-pyrimidin-2-ol 4-cyclopropyl-6-methylpyrimidin-2-ol Not in list C8H10N2O Cc1cc(nc(O)n1)C2CC2 InChI=1/C8H10N2O/c1-5-4-7(6-2-3-6)10-8(11)9-5/h4,6H,2-3H2,1H3,(H,9,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is a metabolite of the substance 4-Cyclopropyl-6-methyl-pyrimidin-2-ol 4-cyclopropyl-6-methylpyrimidin-2-ol Not in list C8H10N2O Cc1cc(nc(O)n1)C2CC2 InChI=1/C8H10N2O/c1-5-4-7(6-2-3-6)10-8(11)9-5/h4,6H,2-3H2,1H3,(H,9,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is a metabolite of the substance 4-Cyclopropyl-6-methyl-pyrimidin-2-ol 4-cyclopropyl-6-methylpyrimidin-2-ol Not in list C8H10N2O Cc1cc(nc(O)n1)C2CC2 InChI=1/C8H10N2O/c1-5-4-7(6-2-3-6)10-8(11)9-5/h4,6H,2-3H2,1H3,(H,9,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is a metabolite of the substance 4-Cyclopropyl-6-methyl-pyrimidin-2-ol 4-cyclopropyl-6-methylpyrimidin-2-ol Not in list C8H10N2O Cc1cc(nc(O)n1)C2CC2 InChI=1/C8H10N2O/c1-5-4-7(6-2-3-6)10-8(11)9-5/h4,6H,2-3H2,1H3,(H,9,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is a metabolite of the substance (2-anilino-6-cyclopropylpyrimidin-4-yl)methanol (2-anilino-6-cyclopropylpyrimidin-4-yl)methanol Not in list C14H15N3O C1CC1C2=CC(=NC(=N2)NC3=CC=CC=C3)CO InChI=1S/C14H15N3O/c18-9-12-8-13(10-6-7-10)17-14(16-12)15-11-4-2-1-3-5-11/h1-5,8,10,18H,6-7,9H2,(H,15,16,17) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is a metabolite of the substance (2-anilino-6-cyclopropylpyrimidin-4-yl)methanol (2-anilino-6-cyclopropylpyrimidin-4-yl)methanol Not in list C14H15N3O C1CC1C2=CC(=NC(=N2)NC3=CC=CC=C3)CO InChI=1S/C14H15N3O/c18-9-12-8-13(10-6-7-10)17-14(16-12)15-11-4-2-1-3-5-11/h1-5,8,10,18H,6-7,9H2,(H,15,16,17) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is a metabolite of the substance (2-anilino-6-cyclopropylpyrimidin-4-yl)methanol (2-anilino-6-cyclopropylpyrimidin-4-yl)methanol Not in list C14H15N3O C1CC1C2=CC(=NC(=N2)NC3=CC=CC=C3)CO InChI=1S/C14H15N3O/c18-9-12-8-13(10-6-7-10)17-14(16-12)15-11-4-2-1-3-5-11/h1-5,8,10,18H,6-7,9H2,(H,15,16,17) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is a metabolite of the substance (2-anilino-6-cyclopropylpyrimidin-4-yl)methanol (2-anilino-6-cyclopropylpyrimidin-4-yl)methanol Not in list C14H15N3O C1CC1C2=CC(=NC(=N2)NC3=CC=CC=C3)CO InChI=1S/C14H15N3O/c18-9-12-8-13(10-6-7-10)17-14(16-12)15-11-4-2-1-3-5-11/h1-5,8,10,18H,6-7,9H2,(H,15,16,17) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is a metabolite of the substance (2-anilino-6-cyclopropylpyrimidin-4-yl)methanol (2-anilino-6-cyclopropylpyrimidin-4-yl)methanol Not in list C14H15N3O C1CC1C2=CC(=NC(=N2)NC3=CC=CC=C3)CO InChI=1S/C14H15N3O/c18-9-12-8-13(10-6-7-10)17-14(16-12)15-11-4-2-1-3-5-11/h1-5,8,10,18H,6-7,9H2,(H,15,16,17) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is a metabolite of the substance (2-anilino-6-cyclopropylpyrimidin-4-yl)methanol (2-anilino-6-cyclopropylpyrimidin-4-yl)methanol Not in list C14H15N3O C1CC1C2=CC(=NC(=N2)NC3=CC=CC=C3)CO InChI=1S/C14H15N3O/c18-9-12-8-13(10-6-7-10)17-14(16-12)15-11-4-2-1-3-5-11/h1-5,8,10,18H,6-7,9H2,(H,15,16,17) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is a metabolite of the substance (2-anilino-6-cyclopropylpyrimidin-4-yl)methanol (2-anilino-6-cyclopropylpyrimidin-4-yl)methanol Not in list C14H15N3O C1CC1C2=CC(=NC(=N2)NC3=CC=CC=C3)CO InChI=1S/C14H15N3O/c18-9-12-8-13(10-6-7-10)17-14(16-12)15-11-4-2-1-3-5-11/h1-5,8,10,18H,6-7,9H2,(H,15,16,17) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is a metabolite of the substance (2-anilino-6-cyclopropylpyrimidin-4-yl)methanol (2-anilino-6-cyclopropylpyrimidin-4-yl)methanol Not in list C14H15N3O C1CC1C2=CC(=NC(=N2)NC3=CC=CC=C3)CO InChI=1S/C14H15N3O/c18-9-12-8-13(10-6-7-10)17-14(16-12)15-11-4-2-1-3-5-11/h1-5,8,10,18H,6-7,9H2,(H,15,16,17) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is a metabolite of the substance (2-anilino-6-cyclopropylpyrimidin-4-yl)methanol (2-anilino-6-cyclopropylpyrimidin-4-yl)methanol Not in list C14H15N3O C1CC1C2=CC(=NC(=N2)NC3=CC=CC=C3)CO InChI=1S/C14H15N3O/c18-9-12-8-13(10-6-7-10)17-14(16-12)15-11-4-2-1-3-5-11/h1-5,8,10,18H,6-7,9H2,(H,15,16,17) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is a metabolite of the substance (2-anilino-6-cyclopropylpyrimidin-4-yl)methanol (2-anilino-6-cyclopropylpyrimidin-4-yl)methanol Not in list C14H15N3O C1CC1C2=CC(=NC(=N2)NC3=CC=CC=C3)CO InChI=1S/C14H15N3O/c18-9-12-8-13(10-6-7-10)17-14(16-12)15-11-4-2-1-3-5-11/h1-5,8,10,18H,6-7,9H2,(H,15,16,17) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is a metabolite of the substance (2-anilino-6-cyclopropylpyrimidin-4-yl)methanol (2-anilino-6-cyclopropylpyrimidin-4-yl)methanol Not in list C14H15N3O C1CC1C2=CC(=NC(=N2)NC3=CC=CC=C3)CO InChI=1S/C14H15N3O/c18-9-12-8-13(10-6-7-10)17-14(16-12)15-11-4-2-1-3-5-11/h1-5,8,10,18H,6-7,9H2,(H,15,16,17) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Cyprodinil 121552-61-2 single chemical entity Component is a metabolite of the substance (2-anilino-6-cyclopropylpyrimidin-4-yl)methanol (2-anilino-6-cyclopropylpyrimidin-4-yl)methanol Not in list C14H15N3O C1CC1C2=CC(=NC(=N2)NC3=CC=CC=C3)CO InChI=1S/C14H15N3O/c18-9-12-8-13(10-6-7-10)17-14(16-12)15-11-4-2-1-3-5-11/h1-5,8,10,18H,6-7,9H2,(H,15,16,17) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Cypronidil 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil 30Jan2006 2006 doi:10.2903/j.efsa.2006.51r
+Dimethomorph 404-200-2 110488-70-5 single chemical entity Component is identical to the substance Dimethomorph 404-200-2 110488-70-5 (E)-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-morpholin-4-ylprop-2-en-1-one Dimethomorph (sum of isomers) C21H22ClNO4 COC1=C(C=C(C=C1)/C(=C/C(=O)N2CCOCC2)/C3=CC=C(C=C3)Cl)OC InChI=1S/C21H22ClNO4/c1-25-19-8-5-16(13-20(19)26-2)18(15-3-6-17(22)7-4-15)14-21(24)23-9-11-27-12-10-23/h3-8,13-14H,9-12H2,1-2H3/b18-14+ organic representative isomer PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Germany Dimethomorph 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethomorph 21Jul2006 2006 doi:10.2903/j.efsa.2006.82r
+Dimethomorph 404-200-2 110488-70-5 single chemical entity Component is identical to the substance Dimethomorph 404-200-2 110488-70-5 (E)-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-morpholin-4-ylprop-2-en-1-one Dimethomorph (sum of isomers) C21H22ClNO4 COC1=C(C=C(C=C1)/C(=C/C(=O)N2CCOCC2)/C3=CC=C(C=C3)Cl)OC InChI=1S/C21H22ClNO4/c1-25-19-8-5-16(13-20(19)26-2)18(15-3-6-17(22)7-4-15)14-21(24)23-9-11-27-12-10-23/h3-8,13-14H,9-12H2,1-2H3/b18-14+ organic representative isomer PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany Dimethomorph 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethomorph 21Jul2006 2006 doi:10.2903/j.efsa.2006.82r
+Dimethomorph 404-200-2 110488-70-5 single chemical entity Component is identical to the substance Dimethomorph 404-200-2 110488-70-5 (E)-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-morpholin-4-ylprop-2-en-1-one Dimethomorph (sum of isomers) C21H22ClNO4 COC1=C(C=C(C=C1)/C(=C/C(=O)N2CCOCC2)/C3=CC=C(C=C3)Cl)OC InChI=1S/C21H22ClNO4/c1-25-19-8-5-16(13-20(19)26-2)18(15-3-6-17(22)7-4-15)14-21(24)23-9-11-27-12-10-23/h3-8,13-14H,9-12H2,1-2H3/b18-14+ organic representative isomer PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany Dimethomorph 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethomorph 21Jul2006 2006 doi:10.2903/j.efsa.2006.82r
+Dimethomorph 404-200-2 110488-70-5 single chemical entity Component is identical to the substance Dimethomorph 404-200-2 110488-70-5 (E)-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-morpholin-4-ylprop-2-en-1-one Dimethomorph (sum of isomers) C21H22ClNO4 COC1=C(C=C(C=C1)/C(=C/C(=O)N2CCOCC2)/C3=CC=C(C=C3)Cl)OC InChI=1S/C21H22ClNO4/c1-25-19-8-5-16(13-20(19)26-2)18(15-3-6-17(22)7-4-15)14-21(24)23-9-11-27-12-10-23/h3-8,13-14H,9-12H2,1-2H3/b18-14+ organic representative isomer PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany Dimethomorph 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethomorph 21Jul2006 2006 doi:10.2903/j.efsa.2006.82r
+Dimethomorph 404-200-2 110488-70-5 single chemical entity Component is identical to the substance Dimethomorph 404-200-2 110488-70-5 (E)-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-morpholin-4-ylprop-2-en-1-one Dimethomorph (sum of isomers) C21H22ClNO4 COC1=C(C=C(C=C1)/C(=C/C(=O)N2CCOCC2)/C3=CC=C(C=C3)Cl)OC InChI=1S/C21H22ClNO4/c1-25-19-8-5-16(13-20(19)26-2)18(15-3-6-17(22)7-4-15)14-21(24)23-9-11-27-12-10-23/h3-8,13-14H,9-12H2,1-2H3/b18-14+ organic representative isomer PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Germany Dimethomorph 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethomorph 21Jul2006 2006 doi:10.2903/j.efsa.2006.82r
+Dimethomorph 404-200-2 110488-70-5 single chemical entity Component is identical to the substance Dimethomorph 404-200-2 110488-70-5 (E)-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-morpholin-4-ylprop-2-en-1-one Dimethomorph (sum of isomers) C21H22ClNO4 COC1=C(C=C(C=C1)/C(=C/C(=O)N2CCOCC2)/C3=CC=C(C=C3)Cl)OC InChI=1S/C21H22ClNO4/c1-25-19-8-5-16(13-20(19)26-2)18(15-3-6-17(22)7-4-15)14-21(24)23-9-11-27-12-10-23/h3-8,13-14H,9-12H2,1-2H3/b18-14+ organic representative isomer PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Germany Dimethomorph 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethomorph 21Jul2006 2006 doi:10.2903/j.efsa.2006.82r
+Dimethomorph 404-200-2 110488-70-5 single chemical entity Component is identical to the substance Dimethomorph 404-200-2 110488-70-5 (E)-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-morpholin-4-ylprop-2-en-1-one Dimethomorph (sum of isomers) C21H22ClNO4 COC1=C(C=C(C=C1)/C(=C/C(=O)N2CCOCC2)/C3=CC=C(C=C3)Cl)OC InChI=1S/C21H22ClNO4/c1-25-19-8-5-16(13-20(19)26-2)18(15-3-6-17(22)7-4-15)14-21(24)23-9-11-27-12-10-23/h3-8,13-14H,9-12H2,1-2H3/b18-14+ organic representative isomer PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany Dimethomorph 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethomorph 21Jul2006 2006 doi:10.2903/j.efsa.2006.82r
+Dimethomorph 404-200-2 110488-70-5 single chemical entity Component is identical to the substance Dimethomorph 404-200-2 110488-70-5 (E)-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-morpholin-4-ylprop-2-en-1-one Dimethomorph (sum of isomers) C21H22ClNO4 COC1=C(C=C(C=C1)/C(=C/C(=O)N2CCOCC2)/C3=CC=C(C=C3)Cl)OC InChI=1S/C21H22ClNO4/c1-25-19-8-5-16(13-20(19)26-2)18(15-3-6-17(22)7-4-15)14-21(24)23-9-11-27-12-10-23/h3-8,13-14H,9-12H2,1-2H3/b18-14+ organic representative isomer PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany Dimethomorph 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethomorph 21Jul2006 2006 doi:10.2903/j.efsa.2006.82r
+Dimethomorph 404-200-2 110488-70-5 single chemical entity Component is identical to the substance Dimethomorph 404-200-2 110488-70-5 (E)-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-morpholin-4-ylprop-2-en-1-one Dimethomorph (sum of isomers) C21H22ClNO4 COC1=C(C=C(C=C1)/C(=C/C(=O)N2CCOCC2)/C3=CC=C(C=C3)Cl)OC InChI=1S/C21H22ClNO4/c1-25-19-8-5-16(13-20(19)26-2)18(15-3-6-17(22)7-4-15)14-21(24)23-9-11-27-12-10-23/h3-8,13-14H,9-12H2,1-2H3/b18-14+ organic representative isomer PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany Dimethomorph 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethomorph 21Jul2006 2006 doi:10.2903/j.efsa.2006.82r
+Dimethomorph 404-200-2 110488-70-5 single chemical entity Component is identical to the substance Dimethomorph 404-200-2 110488-70-5 (E)-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-morpholin-4-ylprop-2-en-1-one Dimethomorph (sum of isomers) C21H22ClNO4 COC1=C(C=C(C=C1)/C(=C/C(=O)N2CCOCC2)/C3=CC=C(C=C3)Cl)OC InChI=1S/C21H22ClNO4/c1-25-19-8-5-16(13-20(19)26-2)18(15-3-6-17(22)7-4-15)14-21(24)23-9-11-27-12-10-23/h3-8,13-14H,9-12H2,1-2H3/b18-14+ organic representative isomer PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Germany Dimethomorph 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethomorph 21Jul2006 2006 doi:10.2903/j.efsa.2006.82r
+Dimethomorph 404-200-2 110488-70-5 single chemical entity Component is identical to the substance Dimethomorph 404-200-2 110488-70-5 (E)-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-morpholin-4-ylprop-2-en-1-one Dimethomorph (sum of isomers) C21H22ClNO4 COC1=C(C=C(C=C1)/C(=C/C(=O)N2CCOCC2)/C3=CC=C(C=C3)Cl)OC InChI=1S/C21H22ClNO4/c1-25-19-8-5-16(13-20(19)26-2)18(15-3-6-17(22)7-4-15)14-21(24)23-9-11-27-12-10-23/h3-8,13-14H,9-12H2,1-2H3/b18-14+ organic representative isomer PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany Dimethomorph 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethomorph 21Jul2006 2006 doi:10.2903/j.efsa.2006.82r
+Dimethomorph 404-200-2 110488-70-5 single chemical entity Component is identical to the substance Dimethomorph 404-200-2 110488-70-5 (E)-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-morpholin-4-ylprop-2-en-1-one Dimethomorph (sum of isomers) C21H22ClNO4 COC1=C(C=C(C=C1)/C(=C/C(=O)N2CCOCC2)/C3=CC=C(C=C3)Cl)OC InChI=1S/C21H22ClNO4/c1-25-19-8-5-16(13-20(19)26-2)18(15-3-6-17(22)7-4-15)14-21(24)23-9-11-27-12-10-23/h3-8,13-14H,9-12H2,1-2H3/b18-14+ organic representative isomer PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany Dimethomorph 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethomorph 21Jul2006 2006 doi:10.2903/j.efsa.2006.82r
+Dimethomorph 404-200-2 110488-70-5 single chemical entity Component is identical to the substance Dimethomorph 404-200-2 110488-70-5 (E)-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-morpholin-4-ylprop-2-en-1-one Dimethomorph (sum of isomers) C21H22ClNO4 COC1=C(C=C(C=C1)/C(=C/C(=O)N2CCOCC2)/C3=CC=C(C=C3)Cl)OC InChI=1S/C21H22ClNO4/c1-25-19-8-5-16(13-20(19)26-2)18(15-3-6-17(22)7-4-15)14-21(24)23-9-11-27-12-10-23/h3-8,13-14H,9-12H2,1-2H3/b18-14+ organic representative isomer PubChem isomeric SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: Germany Dimethomorph 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethomorph 21Jul2006 2006 doi:10.2903/j.efsa.2006.82r
+Dimethomorph 404-200-2 110488-70-5 single chemical entity Component is identical to the substance Dimethomorph 404-200-2 110488-70-5 (E)-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-morpholin-4-ylprop-2-en-1-one Dimethomorph (sum of isomers) C21H22ClNO4 COC1=C(C=C(C=C1)/C(=C/C(=O)N2CCOCC2)/C3=CC=C(C=C3)Cl)OC InChI=1S/C21H22ClNO4/c1-25-19-8-5-16(13-20(19)26-2)18(15-3-6-17(22)7-4-15)14-21(24)23-9-11-27-12-10-23/h3-8,13-14H,9-12H2,1-2H3/b18-14+ organic representative isomer PubChem isomeric SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: Germany Dimethomorph 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethomorph 21Jul2006 2006 doi:10.2903/j.efsa.2006.82r
+Dimethomorph 404-200-2 110488-70-5 single chemical entity Component is identical to the substance Dimethomorph 404-200-2 110488-70-5 (E)-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-morpholin-4-ylprop-2-en-1-one Dimethomorph (sum of isomers) C21H22ClNO4 COC1=C(C=C(C=C1)/C(=C/C(=O)N2CCOCC2)/C3=CC=C(C=C3)Cl)OC InChI=1S/C21H22ClNO4/c1-25-19-8-5-16(13-20(19)26-2)18(15-3-6-17(22)7-4-15)14-21(24)23-9-11-27-12-10-23/h3-8,13-14H,9-12H2,1-2H3/b18-14+ organic representative isomer PubChem isomeric SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Positive RMS: Germany Dimethomorph 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethomorph 21Jul2006 2006 doi:10.2903/j.efsa.2006.82r
+Dimethomorph 404-200-2 110488-70-5 single chemical entity Component is identical to the substance Dimethomorph 404-200-2 110488-70-5 (E)-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-morpholin-4-ylprop-2-en-1-one Dimethomorph (sum of isomers) C21H22ClNO4 COC1=C(C=C(C=C1)/C(=C/C(=O)N2CCOCC2)/C3=CC=C(C=C3)Cl)OC InChI=1S/C21H22ClNO4/c1-25-19-8-5-16(13-20(19)26-2)18(15-3-6-17(22)7-4-15)14-21(24)23-9-11-27-12-10-23/h3-8,13-14H,9-12H2,1-2H3/b18-14+ organic representative isomer PubChem isomeric SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Positive RMS: Germany Dimethomorph 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethomorph 21Jul2006 2006 doi:10.2903/j.efsa.2006.82r
+Dimethomorph 404-200-2 110488-70-5 single chemical entity Component is identical to the substance Dimethomorph 404-200-2 110488-70-5 (E)-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-morpholin-4-ylprop-2-en-1-one Dimethomorph (sum of isomers) C21H22ClNO4 COC1=C(C=C(C=C1)/C(=C/C(=O)N2CCOCC2)/C3=CC=C(C=C3)Cl)OC InChI=1S/C21H22ClNO4/c1-25-19-8-5-16(13-20(19)26-2)18(15-3-6-17(22)7-4-15)14-21(24)23-9-11-27-12-10-23/h3-8,13-14H,9-12H2,1-2H3/b18-14+ organic representative isomer PubChem isomeric SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Ambiguous RMS: Germany Dimethomorph 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethomorph 21Jul2006 2006 doi:10.2903/j.efsa.2006.82r
+Dimethomorph 404-200-2 110488-70-5 single chemical entity Component is identical to the substance Dimethomorph 404-200-2 110488-70-5 (E)-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-morpholin-4-ylprop-2-en-1-one Dimethomorph (sum of isomers) C21H22ClNO4 COC1=C(C=C(C=C1)/C(=C/C(=O)N2CCOCC2)/C3=CC=C(C=C3)Cl)OC InChI=1S/C21H22ClNO4/c1-25-19-8-5-16(13-20(19)26-2)18(15-3-6-17(22)7-4-15)14-21(24)23-9-11-27-12-10-23/h3-8,13-14H,9-12H2,1-2H3/b18-14+ organic representative isomer PubChem isomeric SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Ambiguous RMS: Germany Dimethomorph 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethomorph 21Jul2006 2006 doi:10.2903/j.efsa.2006.82r
+Dimethomorph 404-200-2 110488-70-5 single chemical entity Component is identical to the substance Dimethomorph 404-200-2 110488-70-5 (E)-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-morpholin-4-ylprop-2-en-1-one Dimethomorph (sum of isomers) C21H22ClNO4 COC1=C(C=C(C=C1)/C(=C/C(=O)N2CCOCC2)/C3=CC=C(C=C3)Cl)OC InChI=1S/C21H22ClNO4/c1-25-19-8-5-16(13-20(19)26-2)18(15-3-6-17(22)7-4-15)14-21(24)23-9-11-27-12-10-23/h3-8,13-14H,9-12H2,1-2H3/b18-14+ organic representative isomer PubChem isomeric SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Germany Dimethomorph 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethomorph 21Jul2006 2006 doi:10.2903/j.efsa.2006.82r
+Dimethomorph 404-200-2 110488-70-5 single chemical entity Component is identical to the substance Dimethomorph 404-200-2 110488-70-5 (E)-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-morpholin-4-ylprop-2-en-1-one Dimethomorph (sum of isomers) C21H22ClNO4 COC1=C(C=C(C=C1)/C(=C/C(=O)N2CCOCC2)/C3=CC=C(C=C3)Cl)OC InChI=1S/C21H22ClNO4/c1-25-19-8-5-16(13-20(19)26-2)18(15-3-6-17(22)7-4-15)14-21(24)23-9-11-27-12-10-23/h3-8,13-14H,9-12H2,1-2H3/b18-14+ organic representative isomer PubChem isomeric SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Germany Dimethomorph 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethomorph 21Jul2006 2006 doi:10.2903/j.efsa.2006.82r
+Dimethomorph 404-200-2 110488-70-5 single chemical entity Component is identical to the substance Dimethomorph 404-200-2 110488-70-5 (E)-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-morpholin-4-ylprop-2-en-1-one Dimethomorph (sum of isomers) C21H22ClNO4 COC1=C(C=C(C=C1)/C(=C/C(=O)N2CCOCC2)/C3=CC=C(C=C3)Cl)OC InChI=1S/C21H22ClNO4/c1-25-19-8-5-16(13-20(19)26-2)18(15-3-6-17(22)7-4-15)14-21(24)23-9-11-27-12-10-23/h3-8,13-14H,9-12H2,1-2H3/b18-14+ organic representative isomer PubChem isomeric SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Germany Dimethomorph 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethomorph 21Jul2006 2006 doi:10.2903/j.efsa.2006.82r
+Dimethomorph 404-200-2 110488-70-5 single chemical entity Component is identical to the substance Dimethomorph 404-200-2 110488-70-5 (E)-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-morpholin-4-ylprop-2-en-1-one Dimethomorph (sum of isomers) C21H22ClNO4 COC1=C(C=C(C=C1)/C(=C/C(=O)N2CCOCC2)/C3=CC=C(C=C3)Cl)OC InChI=1S/C21H22ClNO4/c1-25-19-8-5-16(13-20(19)26-2)18(15-3-6-17(22)7-4-15)14-21(24)23-9-11-27-12-10-23/h3-8,13-14H,9-12H2,1-2H3/b18-14+ organic representative isomer PubChem isomeric SMILES PubChem InChI DNA damage and/or repair in vitro mammalian cell transformation assay in vitro No guideline available Not reported Not applicable Acceptable Hamster (as animal) embryo cells Not reported yes without Negative RMS: Germany Dimethomorph 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethomorph 21Jul2006 2006 doi:10.2903/j.efsa.2006.82r
+Dimethomorph 404-200-2 110488-70-5 single chemical entity Component is identical to the substance Dimethomorph 404-200-2 110488-70-5 (E)-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-morpholin-4-ylprop-2-en-1-one Dimethomorph (sum of isomers) C21H22ClNO4 COC1=C(C=C(C=C1)/C(=C/C(=O)N2CCOCC2)/C3=CC=C(C=C3)Cl)OC InChI=1S/C21H22ClNO4/c1-25-19-8-5-16(13-20(19)26-2)18(15-3-6-17(22)7-4-15)14-21(24)23-9-11-27-12-10-23/h3-8,13-14H,9-12H2,1-2H3/b18-14+ organic representative isomer PubChem isomeric SMILES PubChem InChI gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Hamster (as animal) embryo cells Not reported yes with Negative RMS: Germany Dimethomorph 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethomorph 21Jul2006 2006 doi:10.2903/j.efsa.2006.82r
+Dimethomorph 404-200-2 110488-70-5 single chemical entity Component is identical to the substance Dimethomorph 404-200-2 110488-70-5 (E)-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-morpholin-4-ylprop-2-en-1-one Dimethomorph (sum of isomers) C21H22ClNO4 COC1=C(C=C(C=C1)/C(=C/C(=O)N2CCOCC2)/C3=CC=C(C=C3)Cl)OC InChI=1S/C21H22ClNO4/c1-25-19-8-5-16(13-20(19)26-2)18(15-3-6-17(22)7-4-15)14-21(24)23-9-11-27-12-10-23/h3-8,13-14H,9-12H2,1-2H3/b18-14+ organic representative isomer PubChem isomeric SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Swiss 30 Male/Female intraperitoneal 72.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity$indirect evidence-systemic toxicity RMS: Germany Dimethomorph 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethomorph 21Jul2006 2006 doi:10.2903/j.efsa.2006.82r
+Dimethomorph 404-200-2 110488-70-5 single chemical entity Component is identical to the substance Dimethomorph 404-200-2 110488-70-5 (E)-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-morpholin-4-ylprop-2-en-1-one Dimethomorph (sum of isomers) C21H22ClNO4 COC1=C(C=C(C=C1)/C(=C/C(=O)N2CCOCC2)/C3=CC=C(C=C3)Cl)OC InChI=1S/C21H22ClNO4/c1-25-19-8-5-16(13-20(19)26-2)18(15-3-6-17(22)7-4-15)14-21(24)23-9-11-27-12-10-23/h3-8,13-14H,9-12H2,1-2H3/b18-14+ organic representative isomer PubChem isomeric SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Swiss 30 Male/Female intraperitoneal 24.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity$indirect evidence-systemic toxicity RMS: Germany Dimethomorph 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethomorph 21Jul2006 2006 doi:10.2903/j.efsa.2006.82r
+Dimethomorph 404-200-2 110488-70-5 single chemical entity Component is identical to the substance Dimethomorph 404-200-2 110488-70-5 (E)-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-morpholin-4-ylprop-2-en-1-one Dimethomorph (sum of isomers) C21H22ClNO4 COC1=C(C=C(C=C1)/C(=C/C(=O)N2CCOCC2)/C3=CC=C(C=C3)Cl)OC InChI=1S/C21H22ClNO4/c1-25-19-8-5-16(13-20(19)26-2)18(15-3-6-17(22)7-4-15)14-21(24)23-9-11-27-12-10-23/h3-8,13-14H,9-12H2,1-2H3/b18-14+ organic representative isomer PubChem isomeric SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Swiss 30 Male/Female intraperitoneal 48.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity$indirect evidence-systemic toxicity RMS: Germany Dimethomorph 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethomorph 21Jul2006 2006 doi:10.2903/j.efsa.2006.82r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is identical to the substance Dimethachlor 256-625-6 50563-36-5 2-chloro-N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)acetamide Dimethachlor C13H18ClNO2 ClCC(=O)N(CCOC)c1c(C)cccc1C InChI=1S/C13H18ClNO2/c1-10-5-4-6-11(2)13(10)15(7-8-17-3)12(16)9-14/h4-6H,7-9H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is identical to the substance Dimethachlor 256-625-6 50563-36-5 2-chloro-N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)acetamide Dimethachlor C13H18ClNO2 ClCC(=O)N(CCOC)c1c(C)cccc1C InChI=1S/C13H18ClNO2/c1-10-5-4-6-11(2)13(10)15(7-8-17-3)12(16)9-14/h4-6H,7-9H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is identical to the substance Dimethachlor 256-625-6 50563-36-5 2-chloro-N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)acetamide Dimethachlor C13H18ClNO2 ClCC(=O)N(CCOC)c1c(C)cccc1C InChI=1S/C13H18ClNO2/c1-10-5-4-6-11(2)13(10)15(7-8-17-3)12(16)9-14/h4-6H,7-9H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is identical to the substance Dimethachlor 256-625-6 50563-36-5 2-chloro-N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)acetamide Dimethachlor C13H18ClNO2 ClCC(=O)N(CCOC)c1c(C)cccc1C InChI=1S/C13H18ClNO2/c1-10-5-4-6-11(2)13(10)15(7-8-17-3)12(16)9-14/h4-6H,7-9H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is identical to the substance Dimethachlor 256-625-6 50563-36-5 2-chloro-N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)acetamide Dimethachlor C13H18ClNO2 ClCC(=O)N(CCOC)c1c(C)cccc1C InChI=1S/C13H18ClNO2/c1-10-5-4-6-11(2)13(10)15(7-8-17-3)12(16)9-14/h4-6H,7-9H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is identical to the substance Dimethachlor 256-625-6 50563-36-5 2-chloro-N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)acetamide Dimethachlor C13H18ClNO2 ClCC(=O)N(CCOC)c1c(C)cccc1C InChI=1S/C13H18ClNO2/c1-10-5-4-6-11(2)13(10)15(7-8-17-3)12(16)9-14/h4-6H,7-9H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is identical to the substance Dimethachlor 256-625-6 50563-36-5 2-chloro-N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)acetamide Dimethachlor C13H18ClNO2 ClCC(=O)N(CCOC)c1c(C)cccc1C InChI=1S/C13H18ClNO2/c1-10-5-4-6-11(2)13(10)15(7-8-17-3)12(16)9-14/h4-6H,7-9H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is identical to the substance Dimethachlor 256-625-6 50563-36-5 2-chloro-N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)acetamide Dimethachlor C13H18ClNO2 ClCC(=O)N(CCOC)c1c(C)cccc1C InChI=1S/C13H18ClNO2/c1-10-5-4-6-11(2)13(10)15(7-8-17-3)12(16)9-14/h4-6H,7-9H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is identical to the substance Dimethachlor 256-625-6 50563-36-5 2-chloro-N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)acetamide Dimethachlor C13H18ClNO2 ClCC(=O)N(CCOC)c1c(C)cccc1C InChI=1S/C13H18ClNO2/c1-10-5-4-6-11(2)13(10)15(7-8-17-3)12(16)9-14/h4-6H,7-9H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is identical to the substance Dimethachlor 256-625-6 50563-36-5 2-chloro-N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)acetamide Dimethachlor C13H18ClNO2 ClCC(=O)N(CCOC)c1c(C)cccc1C InChI=1S/C13H18ClNO2/c1-10-5-4-6-11(2)13(10)15(7-8-17-3)12(16)9-14/h4-6H,7-9H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is identical to the substance Dimethachlor 256-625-6 50563-36-5 2-chloro-N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)acetamide Dimethachlor C13H18ClNO2 ClCC(=O)N(CCOC)c1c(C)cccc1C InChI=1S/C13H18ClNO2/c1-10-5-4-6-11(2)13(10)15(7-8-17-3)12(16)9-14/h4-6H,7-9H2,1-3H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is identical to the substance Dimethachlor 256-625-6 50563-36-5 2-chloro-N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)acetamide Dimethachlor C13H18ClNO2 ClCC(=O)N(CCOC)c1c(C)cccc1C InChI=1S/C13H18ClNO2/c1-10-5-4-6-11(2)13(10)15(7-8-17-3)12(16)9-14/h4-6H,7-9H2,1-3H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is identical to the substance Dimethachlor 256-625-6 50563-36-5 2-chloro-N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)acetamide Dimethachlor C13H18ClNO2 ClCC(=O)N(CCOC)c1c(C)cccc1C InChI=1S/C13H18ClNO2/c1-10-5-4-6-11(2)13(10)15(7-8-17-3)12(16)9-14/h4-6H,7-9H2,1-3H3 organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes without Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is identical to the substance Dimethachlor 256-625-6 50563-36-5 2-chloro-N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)acetamide Dimethachlor C13H18ClNO2 ClCC(=O)N(CCOC)c1c(C)cccc1C InChI=1S/C13H18ClNO2/c1-10-5-4-6-11(2)13(10)15(7-8-17-3)12(16)9-14/h4-6H,7-9H2,1-3H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is identical to the substance Dimethachlor 256-625-6 50563-36-5 2-chloro-N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)acetamide Dimethachlor C13H18ClNO2 ClCC(=O)N(CCOC)c1c(C)cccc1C InChI=1S/C13H18ClNO2/c1-10-5-4-6-11(2)13(10)15(7-8-17-3)12(16)9-14/h4-6H,7-9H2,1-3H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is identical to the substance Dimethachlor 256-625-6 50563-36-5 2-chloro-N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)acetamide Dimethachlor C13H18ClNO2 ClCC(=O)N(CCOC)c1c(C)cccc1C InChI=1S/C13H18ClNO2/c1-10-5-4-6-11(2)13(10)15(7-8-17-3)12(16)9-14/h4-6H,7-9H2,1-3H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 12 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is identical to the substance Dimethachlor 256-625-6 50563-36-5 2-chloro-N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)acetamide Dimethachlor C13H18ClNO2 ClCC(=O)N(CCOC)c1c(C)cccc1C InChI=1S/C13H18ClNO2/c1-10-5-4-6-11(2)13(10)15(7-8-17-3)12(16)9-14/h4-6H,7-9H2,1-3H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 12 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is identical to the substance Dimethachlor 256-625-6 50563-36-5 2-chloro-N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)acetamide Dimethachlor C13H18ClNO2 ClCC(=O)N(CCOC)c1c(C)cccc1C InChI=1S/C13H18ClNO2/c1-10-5-4-6-11(2)13(10)15(7-8-17-3)12(16)9-14/h4-6H,7-9H2,1-3H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 12 Male/Female oral: gavage 72.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)oxalamic acid [(2,6-dimethylphenyl)(2-methoxyethyl)amino](oxo)acetic acid Not in list C13H17NO4 O=C(O)C(=O)N(CCOC)c1c(C)cccc1C InChI=1/C13H17NO4/c1-9-5-4-6-10(2)11(9)14(7-8-18-3)12(15)13(16)17/h4-6H,7-8H2,1-3H3,(H,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)oxalamic acid [(2,6-dimethylphenyl)(2-methoxyethyl)amino](oxo)acetic acid Not in list C13H17NO4 O=C(O)C(=O)N(CCOC)c1c(C)cccc1C InChI=1/C13H17NO4/c1-9-5-4-6-10(2)11(9)14(7-8-18-3)12(15)13(16)17/h4-6H,7-8H2,1-3H3,(H,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes without Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)oxalamic acid [(2,6-dimethylphenyl)(2-methoxyethyl)amino](oxo)acetic acid Not in list C13H17NO4 O=C(O)C(=O)N(CCOC)c1c(C)cccc1C InChI=1/C13H17NO4/c1-9-5-4-6-10(2)11(9)14(7-8-18-3)12(15)13(16)17/h4-6H,7-8H2,1-3H3,(H,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)oxalamic acid [(2,6-dimethylphenyl)(2-methoxyethyl)amino](oxo)acetic acid Not in list C13H17NO4 O=C(O)C(=O)N(CCOC)c1c(C)cccc1C InChI=1/C13H17NO4/c1-9-5-4-6-10(2)11(9)14(7-8-18-3)12(15)13(16)17/h4-6H,7-8H2,1-3H3,(H,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)oxalamic acid [(2,6-dimethylphenyl)(2-methoxyethyl)amino](oxo)acetic acid Not in list C13H17NO4 O=C(O)C(=O)N(CCOC)c1c(C)cccc1C InChI=1/C13H17NO4/c1-9-5-4-6-10(2)11(9)14(7-8-18-3)12(15)13(16)17/h4-6H,7-8H2,1-3H3,(H,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)oxalamic acid [(2,6-dimethylphenyl)(2-methoxyethyl)amino](oxo)acetic acid Not in list C13H17NO4 O=C(O)C(=O)N(CCOC)c1c(C)cccc1C InChI=1/C13H17NO4/c1-9-5-4-6-10(2)11(9)14(7-8-18-3)12(15)13(16)17/h4-6H,7-8H2,1-3H3,(H,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)oxalamic acid [(2,6-dimethylphenyl)(2-methoxyethyl)amino](oxo)acetic acid Not in list C13H17NO4 O=C(O)C(=O)N(CCOC)c1c(C)cccc1C InChI=1/C13H17NO4/c1-9-5-4-6-10(2)11(9)14(7-8-18-3)12(15)13(16)17/h4-6H,7-8H2,1-3H3,(H,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)oxalamic acid [(2,6-dimethylphenyl)(2-methoxyethyl)amino](oxo)acetic acid Not in list C13H17NO4 O=C(O)C(=O)N(CCOC)c1c(C)cccc1C InChI=1/C13H17NO4/c1-9-5-4-6-10(2)11(9)14(7-8-18-3)12(15)13(16)17/h4-6H,7-8H2,1-3H3,(H,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)oxalamic acid [(2,6-dimethylphenyl)(2-methoxyethyl)amino](oxo)acetic acid Not in list C13H17NO4 O=C(O)C(=O)N(CCOC)c1c(C)cccc1C InChI=1/C13H17NO4/c1-9-5-4-6-10(2)11(9)14(7-8-18-3)12(15)13(16)17/h4-6H,7-8H2,1-3H3,(H,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)oxalamic acid [(2,6-dimethylphenyl)(2-methoxyethyl)amino](oxo)acetic acid Not in list C13H17NO4 O=C(O)C(=O)N(CCOC)c1c(C)cccc1C InChI=1/C13H17NO4/c1-9-5-4-6-10(2)11(9)14(7-8-18-3)12(15)13(16)17/h4-6H,7-8H2,1-3H3,(H,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)oxalamic acid [(2,6-dimethylphenyl)(2-methoxyethyl)amino](oxo)acetic acid Not in list C13H17NO4 O=C(O)C(=O)N(CCOC)c1c(C)cccc1C InChI=1/C13H17NO4/c1-9-5-4-6-10(2)11(9)14(7-8-18-3)12(15)13(16)17/h4-6H,7-8H2,1-3H3,(H,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes with Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)oxalamic acid [(2,6-dimethylphenyl)(2-methoxyethyl)amino](oxo)acetic acid Not in list C13H17NO4 O=C(O)C(=O)N(CCOC)c1c(C)cccc1C InChI=1/C13H17NO4/c1-9-5-4-6-10(2)11(9)14(7-8-18-3)12(15)13(16)17/h4-6H,7-8H2,1-3H3,(H,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)oxalamic acid [(2,6-dimethylphenyl)(2-methoxyethyl)amino](oxo)acetic acid Not in list C13H17NO4 O=C(O)C(=O)N(CCOC)c1c(C)cccc1C InChI=1/C13H17NO4/c1-9-5-4-6-10(2)11(9)14(7-8-18-3)12(15)13(16)17/h4-6H,7-8H2,1-3H3,(H,16,17) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Negative no information RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)oxalamic acid [(2,6-dimethylphenyl)(2-methoxyethyl)amino](oxo)acetic acid Not in list C13H17NO4 O=C(O)C(=O)N(CCOC)c1c(C)cccc1C InChI=1/C13H17NO4/c1-9-5-4-6-10(2)11(9)14(7-8-18-3)12(15)13(16)17/h4-6H,7-8H2,1-3H3,(H,16,17) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative no information RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)oxalamic acid [(2,6-dimethylphenyl)(2-methoxyethyl)amino](oxo)acetic acid Not in list C13H17NO4 O=C(O)C(=O)N(CCOC)c1c(C)cccc1C InChI=1/C13H17NO4/c1-9-5-4-6-10(2)11(9)14(7-8-18-3)12(15)13(16)17/h4-6H,7-8H2,1-3H3,(H,16,17) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)oxalamic acid [(2,6-dimethylphenyl)(2-methoxyethyl)amino](oxo)acetic acid Not in list C13H17NO4 O=C(O)C(=O)N(CCOC)c1c(C)cccc1C InChI=1/C13H17NO4/c1-9-5-4-6-10(2)11(9)14(7-8-18-3)12(15)13(16)17/h4-6H,7-8H2,1-3H3,(H,16,17) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance [(2,6-dimethylphenyl)-(2-methoxyethyl) carbamoyl]methanesulfonic acid sodium salt sodium 2-[(2,6-dimethylphenyl)(2-methoxyethyl)amino]-2-oxoethanesulfonate Not in list C13H18NNaO5S O=S(=O)(O[Na])CC(=O)N(CCOC)c1c(C)cccc1C InChI=1/C13H19NO5S.Na/c1-10-5-4-6-11(2)13(10)14(7-8-19-3)12(15)9-20(16,17)18;/h4-6H,7-9H2,1-3H3,(H,16,17,18);/q;+1/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance [(2,6-dimethylphenyl)-(2-methoxyethyl) carbamoyl]methanesulfonic acid sodium salt sodium 2-[(2,6-dimethylphenyl)(2-methoxyethyl)amino]-2-oxoethanesulfonate Not in list C13H18NNaO5S O=S(=O)(O[Na])CC(=O)N(CCOC)c1c(C)cccc1C InChI=1/C13H19NO5S.Na/c1-10-5-4-6-11(2)13(10)14(7-8-19-3)12(15)9-20(16,17)18;/h4-6H,7-9H2,1-3H3,(H,16,17,18);/q;+1/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance [(2,6-dimethylphenyl)-(2-methoxyethyl) carbamoyl]methanesulfonic acid sodium salt sodium 2-[(2,6-dimethylphenyl)(2-methoxyethyl)amino]-2-oxoethanesulfonate Not in list C13H18NNaO5S O=S(=O)(O[Na])CC(=O)N(CCOC)c1c(C)cccc1C InChI=1/C13H19NO5S.Na/c1-10-5-4-6-11(2)13(10)14(7-8-19-3)12(15)9-20(16,17)18;/h4-6H,7-9H2,1-3H3,(H,16,17,18);/q;+1/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance [(2,6-dimethylphenyl)-(2-methoxyethyl) carbamoyl]methanesulfonic acid sodium salt sodium 2-[(2,6-dimethylphenyl)(2-methoxyethyl)amino]-2-oxoethanesulfonate Not in list C13H18NNaO5S O=S(=O)(O[Na])CC(=O)N(CCOC)c1c(C)cccc1C InChI=1/C13H19NO5S.Na/c1-10-5-4-6-11(2)13(10)14(7-8-19-3)12(15)9-20(16,17)18;/h4-6H,7-9H2,1-3H3,(H,16,17,18);/q;+1/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance [(2,6-dimethylphenyl)-(2-methoxyethyl) carbamoyl]methanesulfonic acid sodium salt sodium 2-[(2,6-dimethylphenyl)(2-methoxyethyl)amino]-2-oxoethanesulfonate Not in list C13H18NNaO5S O=S(=O)(O[Na])CC(=O)N(CCOC)c1c(C)cccc1C InChI=1/C13H19NO5S.Na/c1-10-5-4-6-11(2)13(10)14(7-8-19-3)12(15)9-20(16,17)18;/h4-6H,7-9H2,1-3H3,(H,16,17,18);/q;+1/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes without Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance [(2,6-dimethylphenyl)-(2-methoxyethyl) carbamoyl]methanesulfonic acid sodium salt sodium 2-[(2,6-dimethylphenyl)(2-methoxyethyl)amino]-2-oxoethanesulfonate Not in list C13H18NNaO5S O=S(=O)(O[Na])CC(=O)N(CCOC)c1c(C)cccc1C InChI=1/C13H19NO5S.Na/c1-10-5-4-6-11(2)13(10)14(7-8-19-3)12(15)9-20(16,17)18;/h4-6H,7-9H2,1-3H3,(H,16,17,18);/q;+1/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance [(2,6-dimethylphenyl)-(2-methoxyethyl) carbamoyl]methanesulfonic acid sodium salt sodium 2-[(2,6-dimethylphenyl)(2-methoxyethyl)amino]-2-oxoethanesulfonate Not in list C13H18NNaO5S O=S(=O)(O[Na])CC(=O)N(CCOC)c1c(C)cccc1C InChI=1/C13H19NO5S.Na/c1-10-5-4-6-11(2)13(10)14(7-8-19-3)12(15)9-20(16,17)18;/h4-6H,7-9H2,1-3H3,(H,16,17,18);/q;+1/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance [(2,6-dimethylphenyl)-(2-methoxyethyl) carbamoyl]methanesulfonic acid sodium salt sodium 2-[(2,6-dimethylphenyl)(2-methoxyethyl)amino]-2-oxoethanesulfonate Not in list C13H18NNaO5S O=S(=O)(O[Na])CC(=O)N(CCOC)c1c(C)cccc1C InChI=1/C13H19NO5S.Na/c1-10-5-4-6-11(2)13(10)14(7-8-19-3)12(15)9-20(16,17)18;/h4-6H,7-9H2,1-3H3,(H,16,17,18);/q;+1/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance [(2,6-dimethylphenyl)-(2-methoxyethyl) carbamoyl]methanesulfonic acid sodium salt sodium 2-[(2,6-dimethylphenyl)(2-methoxyethyl)amino]-2-oxoethanesulfonate Not in list C13H18NNaO5S O=S(=O)(O[Na])CC(=O)N(CCOC)c1c(C)cccc1C InChI=1/C13H19NO5S.Na/c1-10-5-4-6-11(2)13(10)14(7-8-19-3)12(15)9-20(16,17)18;/h4-6H,7-9H2,1-3H3,(H,16,17,18);/q;+1/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes with Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance [(2,6-dimethylphenyl)-(2-methoxyethyl) carbamoyl]methanesulfonic acid sodium salt sodium 2-[(2,6-dimethylphenyl)(2-methoxyethyl)amino]-2-oxoethanesulfonate Not in list C13H18NNaO5S O=S(=O)(O[Na])CC(=O)N(CCOC)c1c(C)cccc1C InChI=1/C13H19NO5S.Na/c1-10-5-4-6-11(2)13(10)14(7-8-19-3)12(15)9-20(16,17)18;/h4-6H,7-9H2,1-3H3,(H,16,17,18);/q;+1/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance [(2,6-dimethylphenyl)-(2-methoxyethyl) carbamoyl]methanesulfonic acid sodium salt sodium 2-[(2,6-dimethylphenyl)(2-methoxyethyl)amino]-2-oxoethanesulfonate Not in list C13H18NNaO5S O=S(=O)(O[Na])CC(=O)N(CCOC)c1c(C)cccc1C InChI=1/C13H19NO5S.Na/c1-10-5-4-6-11(2)13(10)14(7-8-19-3)12(15)9-20(16,17)18;/h4-6H,7-9H2,1-3H3,(H,16,17,18);/q;+1/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance [(2,6-dimethylphenyl)-(2-methoxyethyl) carbamoyl]methanesulfonic acid sodium salt sodium 2-[(2,6-dimethylphenyl)(2-methoxyethyl)amino]-2-oxoethanesulfonate Not in list C13H18NNaO5S O=S(=O)(O[Na])CC(=O)N(CCOC)c1c(C)cccc1C InChI=1/C13H19NO5S.Na/c1-10-5-4-6-11(2)13(10)14(7-8-19-3)12(15)9-20(16,17)18;/h4-6H,7-9H2,1-3H3,(H,16,17,18);/q;+1/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance [(2,6-dimethylphenyl)-(2-methoxyethyl) carbamoyl]methanesulfonic acid sodium salt sodium 2-[(2,6-dimethylphenyl)(2-methoxyethyl)amino]-2-oxoethanesulfonate Not in list C13H18NNaO5S O=S(=O)(O[Na])CC(=O)N(CCOC)c1c(C)cccc1C InChI=1/C13H19NO5S.Na/c1-10-5-4-6-11(2)13(10)14(7-8-19-3)12(15)9-20(16,17)18;/h4-6H,7-9H2,1-3H3,(H,16,17,18);/q;+1/p-1 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative no information RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance [(2,6-dimethylphenyl)-(2-methoxyethyl) carbamoyl]methanesulfonic acid sodium salt sodium 2-[(2,6-dimethylphenyl)(2-methoxyethyl)amino]-2-oxoethanesulfonate Not in list C13H18NNaO5S O=S(=O)(O[Na])CC(=O)N(CCOC)c1c(C)cccc1C InChI=1/C13H19NO5S.Na/c1-10-5-4-6-11(2)13(10)14(7-8-19-3)12(15)9-20(16,17)18;/h4-6H,7-9H2,1-3H3,(H,16,17,18);/q;+1/p-1 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Negative no information RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance [(2,6-dimethylphenyl)-(2-methoxyethyl) carbamoyl]methanesulfonic acid sodium salt sodium 2-[(2,6-dimethylphenyl)(2-methoxyethyl)amino]-2-oxoethanesulfonate Not in list C13H18NNaO5S O=S(=O)(O[Na])CC(=O)N(CCOC)c1c(C)cccc1C InChI=1/C13H19NO5S.Na/c1-10-5-4-6-11(2)13(10)14(7-8-19-3)12(15)9-20(16,17)18;/h4-6H,7-9H2,1-3H3,(H,16,17,18);/q;+1/p-1 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes without Negative no information RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance [(2,6-dimethylphenyl)-(2-methoxyethyl) carbamoyl]methanesulfonic acid sodium salt sodium 2-[(2,6-dimethylphenyl)(2-methoxyethyl)amino]-2-oxoethanesulfonate Not in list C13H18NNaO5S O=S(=O)(O[Na])CC(=O)N(CCOC)c1c(C)cccc1C InChI=1/C13H19NO5S.Na/c1-10-5-4-6-11(2)13(10)14(7-8-19-3)12(15)9-20(16,17)18;/h4-6H,7-9H2,1-3H3,(H,16,17,18);/q;+1/p-1 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative no information RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance (2,6-dimethylphenylcarbamoyl)-methanesulfonic acid sodium salt sodium 2-[(2,6-dimethylphenyl)amino]-2-oxoethanesulfonate Not in list C10H12NNaO4S O=C(Nc1c(C)cccc1C)CS(=O)(=O)O[Na] InChI=1/C10H13NO4S.Na/c1-7-4-3-5-8(2)10(7)11-9(12)6-16(13,14)15;/h3-5H,6H2,1-2H3,(H,11,12)(H,13,14,15);/q;+1/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance (2,6-dimethylphenylcarbamoyl)-methanesulfonic acid sodium salt sodium 2-[(2,6-dimethylphenyl)amino]-2-oxoethanesulfonate Not in list C10H12NNaO4S O=C(Nc1c(C)cccc1C)CS(=O)(=O)O[Na] InChI=1/C10H13NO4S.Na/c1-7-4-3-5-8(2)10(7)11-9(12)6-16(13,14)15;/h3-5H,6H2,1-2H3,(H,11,12)(H,13,14,15);/q;+1/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported no data with Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance (2,6-dimethylphenylcarbamoyl)-methanesulfonic acid sodium salt sodium 2-[(2,6-dimethylphenyl)amino]-2-oxoethanesulfonate Not in list C10H12NNaO4S O=C(Nc1c(C)cccc1C)CS(=O)(=O)O[Na] InChI=1/C10H13NO4S.Na/c1-7-4-3-5-8(2)10(7)11-9(12)6-16(13,14)15;/h3-5H,6H2,1-2H3,(H,11,12)(H,13,14,15);/q;+1/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance (2,6-dimethylphenylcarbamoyl)-methanesulfonic acid sodium salt sodium 2-[(2,6-dimethylphenyl)amino]-2-oxoethanesulfonate Not in list C10H12NNaO4S O=C(Nc1c(C)cccc1C)CS(=O)(=O)O[Na] InChI=1/C10H13NO4S.Na/c1-7-4-3-5-8(2)10(7)11-9(12)6-16(13,14)15;/h3-5H,6H2,1-2H3,(H,11,12)(H,13,14,15);/q;+1/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported no data without Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance (2,6-dimethylphenylcarbamoyl)-methanesulfonic acid sodium salt sodium 2-[(2,6-dimethylphenyl)amino]-2-oxoethanesulfonate Not in list C10H12NNaO4S O=C(Nc1c(C)cccc1C)CS(=O)(=O)O[Na] InChI=1/C10H13NO4S.Na/c1-7-4-3-5-8(2)10(7)11-9(12)6-16(13,14)15;/h3-5H,6H2,1-2H3,(H,11,12)(H,13,14,15);/q;+1/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance (2,6-dimethylphenylcarbamoyl)-methanesulfonic acid sodium salt sodium 2-[(2,6-dimethylphenyl)amino]-2-oxoethanesulfonate Not in list C10H12NNaO4S O=C(Nc1c(C)cccc1C)CS(=O)(=O)O[Na] InChI=1/C10H13NO4S.Na/c1-7-4-3-5-8(2)10(7)11-9(12)6-16(13,14)15;/h3-5H,6H2,1-2H3,(H,11,12)(H,13,14,15);/q;+1/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance (2,6-dimethylphenylcarbamoyl)-methanesulfonic acid sodium salt sodium 2-[(2,6-dimethylphenyl)amino]-2-oxoethanesulfonate Not in list C10H12NNaO4S O=C(Nc1c(C)cccc1C)CS(=O)(=O)O[Na] InChI=1/C10H13NO4S.Na/c1-7-4-3-5-8(2)10(7)11-9(12)6-16(13,14)15;/h3-5H,6H2,1-2H3,(H,11,12)(H,13,14,15);/q;+1/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance (2,6-dimethylphenylcarbamoyl)-methanesulfonic acid sodium salt sodium 2-[(2,6-dimethylphenyl)amino]-2-oxoethanesulfonate Not in list C10H12NNaO4S O=C(Nc1c(C)cccc1C)CS(=O)(=O)O[Na] InChI=1/C10H13NO4S.Na/c1-7-4-3-5-8(2)10(7)11-9(12)6-16(13,14)15;/h3-5H,6H2,1-2H3,(H,11,12)(H,13,14,15);/q;+1/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance (2,6-dimethylphenylcarbamoyl)-methanesulfonic acid sodium salt sodium 2-[(2,6-dimethylphenyl)amino]-2-oxoethanesulfonate Not in list C10H12NNaO4S O=C(Nc1c(C)cccc1C)CS(=O)(=O)O[Na] InChI=1/C10H13NO4S.Na/c1-7-4-3-5-8(2)10(7)11-9(12)6-16(13,14)15;/h3-5H,6H2,1-2H3,(H,11,12)(H,13,14,15);/q;+1/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance (2,6-dimethylphenylcarbamoyl)-methanesulfonic acid sodium salt sodium 2-[(2,6-dimethylphenyl)amino]-2-oxoethanesulfonate Not in list C10H12NNaO4S O=C(Nc1c(C)cccc1C)CS(=O)(=O)O[Na] InChI=1/C10H13NO4S.Na/c1-7-4-3-5-8(2)10(7)11-9(12)6-16(13,14)15;/h3-5H,6H2,1-2H3,(H,11,12)(H,13,14,15);/q;+1/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance (2,6-dimethylphenylcarbamoyl)-methanesulfonic acid sodium salt sodium 2-[(2,6-dimethylphenyl)amino]-2-oxoethanesulfonate Not in list C10H12NNaO4S O=C(Nc1c(C)cccc1C)CS(=O)(=O)O[Na] InChI=1/C10H13NO4S.Na/c1-7-4-3-5-8(2)10(7)11-9(12)6-16(13,14)15;/h3-5H,6H2,1-2H3,(H,11,12)(H,13,14,15);/q;+1/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance (2,6-dimethylphenylcarbamoyl)-methanesulfonic acid sodium salt sodium 2-[(2,6-dimethylphenyl)amino]-2-oxoethanesulfonate Not in list C10H12NNaO4S O=C(Nc1c(C)cccc1C)CS(=O)(=O)O[Na] InChI=1/C10H13NO4S.Na/c1-7-4-3-5-8(2)10(7)11-9(12)6-16(13,14)15;/h3-5H,6H2,1-2H3,(H,11,12)(H,13,14,15);/q;+1/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance (2,6-dimethylphenylcarbamoyl)-methanesulfonic acid sodium salt sodium 2-[(2,6-dimethylphenyl)amino]-2-oxoethanesulfonate Not in list C10H12NNaO4S O=C(Nc1c(C)cccc1C)CS(=O)(=O)O[Na] InChI=1/C10H13NO4S.Na/c1-7-4-3-5-8(2)10(7)11-9(12)6-16(13,14)15;/h3-5H,6H2,1-2H3,(H,11,12)(H,13,14,15);/q;+1/p-1 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data with Negative no information RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance (2,6-dimethylphenylcarbamoyl)-methanesulfonic acid sodium salt sodium 2-[(2,6-dimethylphenyl)amino]-2-oxoethanesulfonate Not in list C10H12NNaO4S O=C(Nc1c(C)cccc1C)CS(=O)(=O)O[Na] InChI=1/C10H13NO4S.Na/c1-7-4-3-5-8(2)10(7)11-9(12)6-16(13,14)15;/h3-5H,6H2,1-2H3,(H,11,12)(H,13,14,15);/q;+1/p-1 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data without Negative no information RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance (2,6-dimethylphenylcarbamoyl)-methanesulfonic acid sodium salt sodium 2-[(2,6-dimethylphenyl)amino]-2-oxoethanesulfonate Not in list C10H12NNaO4S O=C(Nc1c(C)cccc1C)CS(=O)(=O)O[Na] InChI=1/C10H13NO4S.Na/c1-7-4-3-5-8(2)10(7)11-9(12)6-16(13,14)15;/h3-5H,6H2,1-2H3,(H,11,12)(H,13,14,15);/q;+1/p-1 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported no data without Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance (2,6-dimethylphenylcarbamoyl)-methanesulfonic acid sodium salt sodium 2-[(2,6-dimethylphenyl)amino]-2-oxoethanesulfonate Not in list C10H12NNaO4S O=C(Nc1c(C)cccc1C)CS(=O)(=O)O[Na] InChI=1/C10H13NO4S.Na/c1-7-4-3-5-8(2)10(7)11-9(12)6-16(13,14)15;/h3-5H,6H2,1-2H3,(H,11,12)(H,13,14,15);/q;+1/p-1 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported no data with Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance [(2,6-dimethylphenyl)-(2-sulfoacetyl)amino]acetic acid sodium salt sodium 2-[(2,6-dimethylphenyl)(2-methoxy-2-oxoethyl)amino]-2-oxoethanesulfonate Not in list C13H16NnaO6S O=S(=O)(O[Na])CC(=O)N(CC(=O)OC)c1c(C)cccc1C InChI=1/C13H17NO6S.Na/c1-9-5-4-6-10(2)13(9)14(7-12(16)20-3)11(15)8-21(17,18)19;/h4-6H,7-8H2,1-3H3,(H,17,18,19);/q;+1/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance [(2,6-dimethylphenyl)-(2-sulfoacetyl)amino]acetic acid sodium salt sodium 2-[(2,6-dimethylphenyl)(2-methoxy-2-oxoethyl)amino]-2-oxoethanesulfonate Not in list C13H16NnaO6S O=S(=O)(O[Na])CC(=O)N(CC(=O)OC)c1c(C)cccc1C InChI=1/C13H17NO6S.Na/c1-9-5-4-6-10(2)13(9)14(7-12(16)20-3)11(15)8-21(17,18)19;/h4-6H,7-8H2,1-3H3,(H,17,18,19);/q;+1/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance [(2,6-dimethylphenyl)-(2-sulfoacetyl)amino]acetic acid sodium salt sodium 2-[(2,6-dimethylphenyl)(2-methoxy-2-oxoethyl)amino]-2-oxoethanesulfonate Not in list C13H16NnaO6S O=S(=O)(O[Na])CC(=O)N(CC(=O)OC)c1c(C)cccc1C InChI=1/C13H17NO6S.Na/c1-9-5-4-6-10(2)13(9)14(7-12(16)20-3)11(15)8-21(17,18)19;/h4-6H,7-8H2,1-3H3,(H,17,18,19);/q;+1/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance [(2,6-dimethylphenyl)-(2-sulfoacetyl)amino]acetic acid sodium salt sodium 2-[(2,6-dimethylphenyl)(2-methoxy-2-oxoethyl)amino]-2-oxoethanesulfonate Not in list C13H16NnaO6S O=S(=O)(O[Na])CC(=O)N(CC(=O)OC)c1c(C)cccc1C InChI=1/C13H17NO6S.Na/c1-9-5-4-6-10(2)13(9)14(7-12(16)20-3)11(15)8-21(17,18)19;/h4-6H,7-8H2,1-3H3,(H,17,18,19);/q;+1/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance [(2,6-dimethylphenyl)-(2-sulfoacetyl)amino]acetic acid sodium salt sodium 2-[(2,6-dimethylphenyl)(2-methoxy-2-oxoethyl)amino]-2-oxoethanesulfonate Not in list C13H16NnaO6S O=S(=O)(O[Na])CC(=O)N(CC(=O)OC)c1c(C)cccc1C InChI=1/C13H17NO6S.Na/c1-9-5-4-6-10(2)13(9)14(7-12(16)20-3)11(15)8-21(17,18)19;/h4-6H,7-8H2,1-3H3,(H,17,18,19);/q;+1/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance [(2,6-dimethylphenyl)-(2-sulfoacetyl)amino]acetic acid sodium salt sodium 2-[(2,6-dimethylphenyl)(2-methoxy-2-oxoethyl)amino]-2-oxoethanesulfonate Not in list C13H16NnaO6S O=S(=O)(O[Na])CC(=O)N(CC(=O)OC)c1c(C)cccc1C InChI=1/C13H17NO6S.Na/c1-9-5-4-6-10(2)13(9)14(7-12(16)20-3)11(15)8-21(17,18)19;/h4-6H,7-8H2,1-3H3,(H,17,18,19);/q;+1/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance [(2,6-dimethylphenyl)-(2-sulfoacetyl)amino]acetic acid sodium salt sodium 2-[(2,6-dimethylphenyl)(2-methoxy-2-oxoethyl)amino]-2-oxoethanesulfonate Not in list C13H16NnaO6S O=S(=O)(O[Na])CC(=O)N(CC(=O)OC)c1c(C)cccc1C InChI=1/C13H17NO6S.Na/c1-9-5-4-6-10(2)13(9)14(7-12(16)20-3)11(15)8-21(17,18)19;/h4-6H,7-8H2,1-3H3,(H,17,18,19);/q;+1/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported no data without Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance [(2,6-dimethylphenyl)-(2-sulfoacetyl)amino]acetic acid sodium salt sodium 2-[(2,6-dimethylphenyl)(2-methoxy-2-oxoethyl)amino]-2-oxoethanesulfonate Not in list C13H16NnaO6S O=S(=O)(O[Na])CC(=O)N(CC(=O)OC)c1c(C)cccc1C InChI=1/C13H17NO6S.Na/c1-9-5-4-6-10(2)13(9)14(7-12(16)20-3)11(15)8-21(17,18)19;/h4-6H,7-8H2,1-3H3,(H,17,18,19);/q;+1/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance [(2,6-dimethylphenyl)-(2-sulfoacetyl)amino]acetic acid sodium salt sodium 2-[(2,6-dimethylphenyl)(2-methoxy-2-oxoethyl)amino]-2-oxoethanesulfonate Not in list C13H16NnaO6S O=S(=O)(O[Na])CC(=O)N(CC(=O)OC)c1c(C)cccc1C InChI=1/C13H17NO6S.Na/c1-9-5-4-6-10(2)13(9)14(7-12(16)20-3)11(15)8-21(17,18)19;/h4-6H,7-8H2,1-3H3,(H,17,18,19);/q;+1/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance [(2,6-dimethylphenyl)-(2-sulfoacetyl)amino]acetic acid sodium salt sodium 2-[(2,6-dimethylphenyl)(2-methoxy-2-oxoethyl)amino]-2-oxoethanesulfonate Not in list C13H16NnaO6S O=S(=O)(O[Na])CC(=O)N(CC(=O)OC)c1c(C)cccc1C InChI=1/C13H17NO6S.Na/c1-9-5-4-6-10(2)13(9)14(7-12(16)20-3)11(15)8-21(17,18)19;/h4-6H,7-8H2,1-3H3,(H,17,18,19);/q;+1/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance [(2,6-dimethylphenyl)-(2-sulfoacetyl)amino]acetic acid sodium salt sodium 2-[(2,6-dimethylphenyl)(2-methoxy-2-oxoethyl)amino]-2-oxoethanesulfonate Not in list C13H16NnaO6S O=S(=O)(O[Na])CC(=O)N(CC(=O)OC)c1c(C)cccc1C InChI=1/C13H17NO6S.Na/c1-9-5-4-6-10(2)13(9)14(7-12(16)20-3)11(15)8-21(17,18)19;/h4-6H,7-8H2,1-3H3,(H,17,18,19);/q;+1/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported no data with Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance [(2,6-dimethylphenyl)-(2-sulfoacetyl)amino]acetic acid sodium salt sodium 2-[(2,6-dimethylphenyl)(2-methoxy-2-oxoethyl)amino]-2-oxoethanesulfonate Not in list C13H16NnaO6S O=S(=O)(O[Na])CC(=O)N(CC(=O)OC)c1c(C)cccc1C InChI=1/C13H17NO6S.Na/c1-9-5-4-6-10(2)13(9)14(7-12(16)20-3)11(15)8-21(17,18)19;/h4-6H,7-8H2,1-3H3,(H,17,18,19);/q;+1/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance 3-{2-[(2,6-dimethyl-phenyl)-(2-hydroxyacetyl)amino]ethylsulfanyl}-2-hydroxypropionic acid 3-({2-[(2,6-dimethylphenyl)(hydroxyacetyl)amino]ethyl}sulfanyl)-2-hydroxypropanoic acid Not in list C15H21NO5S O=C(O)C(O)CSCCN(C(=O)CO)c1c(C)cccc1C InChI=1/C15H21NO5S/c1-10-4-3-5-11(2)14(10)16(13(19)8-17)6-7-22-9-12(18)15(20)21/h3-5,12,17-18H,6-9H2,1-2H3,(H,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance 3-{2-[(2,6-dimethyl-phenyl)-(2-hydroxyacetyl)amino]ethylsulfanyl}-2-hydroxypropionic acid 3-({2-[(2,6-dimethylphenyl)(hydroxyacetyl)amino]ethyl}sulfanyl)-2-hydroxypropanoic acid Not in list C15H21NO5S O=C(O)C(O)CSCCN(C(=O)CO)c1c(C)cccc1C InChI=1/C15H21NO5S/c1-10-4-3-5-11(2)14(10)16(13(19)8-17)6-7-22-9-12(18)15(20)21/h3-5,12,17-18H,6-9H2,1-2H3,(H,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance 3-{2-[(2,6-dimethyl-phenyl)-(2-hydroxyacetyl)amino]ethylsulfanyl}-2-hydroxypropionic acid 3-({2-[(2,6-dimethylphenyl)(hydroxyacetyl)amino]ethyl}sulfanyl)-2-hydroxypropanoic acid Not in list C15H21NO5S O=C(O)C(O)CSCCN(C(=O)CO)c1c(C)cccc1C InChI=1/C15H21NO5S/c1-10-4-3-5-11(2)14(10)16(13(19)8-17)6-7-22-9-12(18)15(20)21/h3-5,12,17-18H,6-9H2,1-2H3,(H,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported no data without Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance 3-{2-[(2,6-dimethyl-phenyl)-(2-hydroxyacetyl)amino]ethylsulfanyl}-2-hydroxypropionic acid 3-({2-[(2,6-dimethylphenyl)(hydroxyacetyl)amino]ethyl}sulfanyl)-2-hydroxypropanoic acid Not in list C15H21NO5S O=C(O)C(O)CSCCN(C(=O)CO)c1c(C)cccc1C InChI=1/C15H21NO5S/c1-10-4-3-5-11(2)14(10)16(13(19)8-17)6-7-22-9-12(18)15(20)21/h3-5,12,17-18H,6-9H2,1-2H3,(H,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance 3-{2-[(2,6-dimethyl-phenyl)-(2-hydroxyacetyl)amino]ethylsulfanyl}-2-hydroxypropionic acid 3-({2-[(2,6-dimethylphenyl)(hydroxyacetyl)amino]ethyl}sulfanyl)-2-hydroxypropanoic acid Not in list C15H21NO5S O=C(O)C(O)CSCCN(C(=O)CO)c1c(C)cccc1C InChI=1/C15H21NO5S/c1-10-4-3-5-11(2)14(10)16(13(19)8-17)6-7-22-9-12(18)15(20)21/h3-5,12,17-18H,6-9H2,1-2H3,(H,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance 3-{2-[(2,6-dimethyl-phenyl)-(2-hydroxyacetyl)amino]ethylsulfanyl}-2-hydroxypropionic acid 3-({2-[(2,6-dimethylphenyl)(hydroxyacetyl)amino]ethyl}sulfanyl)-2-hydroxypropanoic acid Not in list C15H21NO5S O=C(O)C(O)CSCCN(C(=O)CO)c1c(C)cccc1C InChI=1/C15H21NO5S/c1-10-4-3-5-11(2)14(10)16(13(19)8-17)6-7-22-9-12(18)15(20)21/h3-5,12,17-18H,6-9H2,1-2H3,(H,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance 3-{2-[(2,6-dimethyl-phenyl)-(2-hydroxyacetyl)amino]ethylsulfanyl}-2-hydroxypropionic acid 3-({2-[(2,6-dimethylphenyl)(hydroxyacetyl)amino]ethyl}sulfanyl)-2-hydroxypropanoic acid Not in list C15H21NO5S O=C(O)C(O)CSCCN(C(=O)CO)c1c(C)cccc1C InChI=1/C15H21NO5S/c1-10-4-3-5-11(2)14(10)16(13(19)8-17)6-7-22-9-12(18)15(20)21/h3-5,12,17-18H,6-9H2,1-2H3,(H,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported no data with Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance 3-{2-[(2,6-dimethyl-phenyl)-(2-hydroxyacetyl)amino]ethylsulfanyl}-2-hydroxypropionic acid 3-({2-[(2,6-dimethylphenyl)(hydroxyacetyl)amino]ethyl}sulfanyl)-2-hydroxypropanoic acid Not in list C15H21NO5S O=C(O)C(O)CSCCN(C(=O)CO)c1c(C)cccc1C InChI=1/C15H21NO5S/c1-10-4-3-5-11(2)14(10)16(13(19)8-17)6-7-22-9-12(18)15(20)21/h3-5,12,17-18H,6-9H2,1-2H3,(H,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance 3-{2-[(2,6-dimethyl-phenyl)-(2-hydroxyacetyl)amino]ethylsulfanyl}-2-hydroxypropionic acid 3-({2-[(2,6-dimethylphenyl)(hydroxyacetyl)amino]ethyl}sulfanyl)-2-hydroxypropanoic acid Not in list C15H21NO5S O=C(O)C(O)CSCCN(C(=O)CO)c1c(C)cccc1C InChI=1/C15H21NO5S/c1-10-4-3-5-11(2)14(10)16(13(19)8-17)6-7-22-9-12(18)15(20)21/h3-5,12,17-18H,6-9H2,1-2H3,(H,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance 3-{2-[(2,6-dimethyl-phenyl)-(2-hydroxyacetyl)amino]ethylsulfanyl}-2-hydroxypropionic acid 3-({2-[(2,6-dimethylphenyl)(hydroxyacetyl)amino]ethyl}sulfanyl)-2-hydroxypropanoic acid Not in list C15H21NO5S O=C(O)C(O)CSCCN(C(=O)CO)c1c(C)cccc1C InChI=1/C15H21NO5S/c1-10-4-3-5-11(2)14(10)16(13(19)8-17)6-7-22-9-12(18)15(20)21/h3-5,12,17-18H,6-9H2,1-2H3,(H,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance 3-{2-[(2,6-dimethyl-phenyl)-(2-hydroxyacetyl)amino]ethylsulfanyl}-2-hydroxypropionic acid 3-({2-[(2,6-dimethylphenyl)(hydroxyacetyl)amino]ethyl}sulfanyl)-2-hydroxypropanoic acid Not in list C15H21NO5S O=C(O)C(O)CSCCN(C(=O)CO)c1c(C)cccc1C InChI=1/C15H21NO5S/c1-10-4-3-5-11(2)14(10)16(13(19)8-17)6-7-22-9-12(18)15(20)21/h3-5,12,17-18H,6-9H2,1-2H3,(H,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance 3-{2-[(2,6-dimethyl-phenyl)-(2-hydroxyacetyl)amino]ethylsulfanyl}-2-hydroxypropionic acid 3-({2-[(2,6-dimethylphenyl)(hydroxyacetyl)amino]ethyl}sulfanyl)-2-hydroxypropanoic acid Not in list C15H21NO5S O=C(O)C(O)CSCCN(C(=O)CO)c1c(C)cccc1C InChI=1/C15H21NO5S/c1-10-4-3-5-11(2)14(10)16(13(19)8-17)6-7-22-9-12(18)15(20)21/h3-5,12,17-18H,6-9H2,1-2H3,(H,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance 2-[(2-hydroxyacetyl)-(2-methoxyethyl)amino]-3-methylbenzoic acid 2-[(hydroxyacetyl)(2-methoxyethyl)amino]-3-methylbenzoic acid Not in list C13H17NO5 OCC(=O)N(CCOC)c1c(C)cccc1C(=O)O InChI=1/C13H17NO5/c1-9-4-3-5-10(13(17)18)12(9)14(6-7-19-2)11(16)8-15/h3-5,15H,6-8H2,1-2H3,(H,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported no data without Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance 2-[(2-hydroxyacetyl)-(2-methoxyethyl)amino]-3-methylbenzoic acid 2-[(hydroxyacetyl)(2-methoxyethyl)amino]-3-methylbenzoic acid Not in list C13H17NO5 OCC(=O)N(CCOC)c1c(C)cccc1C(=O)O InChI=1/C13H17NO5/c1-9-4-3-5-10(13(17)18)12(9)14(6-7-19-2)11(16)8-15/h3-5,15H,6-8H2,1-2H3,(H,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance 2-[(2-hydroxyacetyl)-(2-methoxyethyl)amino]-3-methylbenzoic acid 2-[(hydroxyacetyl)(2-methoxyethyl)amino]-3-methylbenzoic acid Not in list C13H17NO5 OCC(=O)N(CCOC)c1c(C)cccc1C(=O)O InChI=1/C13H17NO5/c1-9-4-3-5-10(13(17)18)12(9)14(6-7-19-2)11(16)8-15/h3-5,15H,6-8H2,1-2H3,(H,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported no data with Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance 2-[(2-hydroxyacetyl)-(2-methoxyethyl)amino]-3-methylbenzoic acid 2-[(hydroxyacetyl)(2-methoxyethyl)amino]-3-methylbenzoic acid Not in list C13H17NO5 OCC(=O)N(CCOC)c1c(C)cccc1C(=O)O InChI=1/C13H17NO5/c1-9-4-3-5-10(13(17)18)12(9)14(6-7-19-2)11(16)8-15/h3-5,15H,6-8H2,1-2H3,(H,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance 2-[(2-hydroxyacetyl)-(2-methoxyethyl)amino]-3-methylbenzoic acid 2-[(hydroxyacetyl)(2-methoxyethyl)amino]-3-methylbenzoic acid Not in list C13H17NO5 OCC(=O)N(CCOC)c1c(C)cccc1C(=O)O InChI=1/C13H17NO5/c1-9-4-3-5-10(13(17)18)12(9)14(6-7-19-2)11(16)8-15/h3-5,15H,6-8H2,1-2H3,(H,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance 2-[(2-hydroxyacetyl)-(2-methoxyethyl)amino]-3-methylbenzoic acid 2-[(hydroxyacetyl)(2-methoxyethyl)amino]-3-methylbenzoic acid Not in list C13H17NO5 OCC(=O)N(CCOC)c1c(C)cccc1C(=O)O InChI=1/C13H17NO5/c1-9-4-3-5-10(13(17)18)12(9)14(6-7-19-2)11(16)8-15/h3-5,15H,6-8H2,1-2H3,(H,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance 2-[(2-hydroxyacetyl)-(2-methoxyethyl)amino]-3-methylbenzoic acid 2-[(hydroxyacetyl)(2-methoxyethyl)amino]-3-methylbenzoic acid Not in list C13H17NO5 OCC(=O)N(CCOC)c1c(C)cccc1C(=O)O InChI=1/C13H17NO5/c1-9-4-3-5-10(13(17)18)12(9)14(6-7-19-2)11(16)8-15/h3-5,15H,6-8H2,1-2H3,(H,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance 2-[(2-hydroxyacetyl)-(2-methoxyethyl)amino]-3-methylbenzoic acid 2-[(hydroxyacetyl)(2-methoxyethyl)amino]-3-methylbenzoic acid Not in list C13H17NO5 OCC(=O)N(CCOC)c1c(C)cccc1C(=O)O InChI=1/C13H17NO5/c1-9-4-3-5-10(13(17)18)12(9)14(6-7-19-2)11(16)8-15/h3-5,15H,6-8H2,1-2H3,(H,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance 2-[(2-hydroxyacetyl)-(2-methoxyethyl)amino]-3-methylbenzoic acid 2-[(hydroxyacetyl)(2-methoxyethyl)amino]-3-methylbenzoic acid Not in list C13H17NO5 OCC(=O)N(CCOC)c1c(C)cccc1C(=O)O InChI=1/C13H17NO5/c1-9-4-3-5-10(13(17)18)12(9)14(6-7-19-2)11(16)8-15/h3-5,15H,6-8H2,1-2H3,(H,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance 2-[(2-hydroxyacetyl)-(2-methoxyethyl)amino]-3-methylbenzoic acid 2-[(hydroxyacetyl)(2-methoxyethyl)amino]-3-methylbenzoic acid Not in list C13H17NO5 OCC(=O)N(CCOC)c1c(C)cccc1C(=O)O InChI=1/C13H17NO5/c1-9-4-3-5-10(13(17)18)12(9)14(6-7-19-2)11(16)8-15/h3-5,15H,6-8H2,1-2H3,(H,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance 2-[(2-hydroxyacetyl)-(2-methoxyethyl)amino]-3-methylbenzoic acid 2-[(hydroxyacetyl)(2-methoxyethyl)amino]-3-methylbenzoic acid Not in list C13H17NO5 OCC(=O)N(CCOC)c1c(C)cccc1C(=O)O InChI=1/C13H17NO5/c1-9-4-3-5-10(13(17)18)12(9)14(6-7-19-2)11(16)8-15/h3-5,15H,6-8H2,1-2H3,(H,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is a metabolite of the substance 2-[(2-hydroxyacetyl)-(2-methoxyethyl)amino]-3-methylbenzoic acid 2-[(hydroxyacetyl)(2-methoxyethyl)amino]-3-methylbenzoic acid Not in list C13H17NO5 OCC(=O)N(CCOC)c1c(C)cccc1C(=O)O InChI=1/C13H17NO5/c1-9-4-3-5-10(13(17)18)12(9)14(6-7-19-2)11(16)8-15/h3-5,15H,6-8H2,1-2H3,(H,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Germany Dimethachlor 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Dimethachlor 256-625-6 50563-36-5 single chemical entity Component is identical to the substance Dimethachlor 256-625-6 50563-36-5 2-chloro-N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)acetamide Dimethachlor C13H18ClNO2 ClCC(=O)N(CCOC)c1c(C)cccc1C InChI=1S/C13H18ClNO2/c1-10-5-4-6-11(2)13(10)15(7-8-17-3)12(16)9-14/h4-6H,7-9H2,1-3H3 organic compound Other Other DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable Rat (as animal) Not reported 6 Male oral: unspecified 24.0000000000 h yes not applicable Negative RMS: Germany Dimethachlor (Addendum 1) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor 30Oct2008 2008 doi:10.2903/j.efsa.2008.169r
+Diethofencarb 403-870-3 87130-20-9 single chemical entity Component is identical to the substance Diethofencarb 403-870-3 87130-20-9 isopropyl (3,4-diethoxyphenyl)carbamate Diethofencarb C14H21NO4 O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1 InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Diethofencarb (Revised additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb 20Sep2010 2010 doi:10.2903/j.efsa.2010.1721
+Diethofencarb 403-870-3 87130-20-9 single chemical entity Component is identical to the substance Diethofencarb 403-870-3 87130-20-9 isopropyl (3,4-diethoxyphenyl)carbamate Diethofencarb C14H21NO4 O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1 InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Diethofencarb (Revised additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb 20Sep2010 2010 doi:10.2903/j.efsa.2010.1721
+Diethofencarb 403-870-3 87130-20-9 single chemical entity Component is identical to the substance Diethofencarb 403-870-3 87130-20-9 isopropyl (3,4-diethoxyphenyl)carbamate Diethofencarb C14H21NO4 O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1 InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Diethofencarb (Revised additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb 20Sep2010 2010 doi:10.2903/j.efsa.2010.1721
+Diethofencarb 403-870-3 87130-20-9 single chemical entity Component is identical to the substance Diethofencarb 403-870-3 87130-20-9 isopropyl (3,4-diethoxyphenyl)carbamate Diethofencarb C14H21NO4 O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1 InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: France Diethofencarb (Revised additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb 20Sep2010 2010 doi:10.2903/j.efsa.2010.1721
+Diethofencarb 403-870-3 87130-20-9 single chemical entity Component is identical to the substance Diethofencarb 403-870-3 87130-20-9 isopropyl (3,4-diethoxyphenyl)carbamate Diethofencarb C14H21NO4 O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1 InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: France Diethofencarb (Revised additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb 20Sep2010 2010 doi:10.2903/j.efsa.2010.1721
+Diethofencarb 403-870-3 87130-20-9 single chemical entity Component is identical to the substance Diethofencarb 403-870-3 87130-20-9 isopropyl (3,4-diethoxyphenyl)carbamate Diethofencarb C14H21NO4 O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1 InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: France Diethofencarb (Revised additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb 20Sep2010 2010 doi:10.2903/j.efsa.2010.1721
+Diethofencarb 403-870-3 87130-20-9 single chemical entity Component is identical to the substance Diethofencarb 403-870-3 87130-20-9 isopropyl (3,4-diethoxyphenyl)carbamate Diethofencarb C14H21NO4 O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1 InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Diethofencarb (Revised additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb 20Sep2010 2010 doi:10.2903/j.efsa.2010.1721
+Diethofencarb 403-870-3 87130-20-9 single chemical entity Component is identical to the substance Diethofencarb 403-870-3 87130-20-9 isopropyl (3,4-diethoxyphenyl)carbamate Diethofencarb C14H21NO4 O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1 InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Diethofencarb (Revised additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb 20Sep2010 2010 doi:10.2903/j.efsa.2010.1721
+Diethofencarb 403-870-3 87130-20-9 single chemical entity Component is identical to the substance Diethofencarb 403-870-3 87130-20-9 isopropyl (3,4-diethoxyphenyl)carbamate Diethofencarb C14H21NO4 O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1 InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Diethofencarb (Revised additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb 20Sep2010 2010 doi:10.2903/j.efsa.2010.1721
+Diethofencarb 403-870-3 87130-20-9 single chemical entity Component is identical to the substance Diethofencarb 403-870-3 87130-20-9 isopropyl (3,4-diethoxyphenyl)carbamate Diethofencarb C14H21NO4 O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1 InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Diethofencarb (Revised additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb 20Sep2010 2010 doi:10.2903/j.efsa.2010.1721
+Diethofencarb 403-870-3 87130-20-9 single chemical entity Component is identical to the substance Diethofencarb 403-870-3 87130-20-9 isopropyl (3,4-diethoxyphenyl)carbamate Diethofencarb C14H21NO4 O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1 InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: France Diethofencarb (Revised additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb 20Sep2010 2010 doi:10.2903/j.efsa.2010.1721
+Diethofencarb 403-870-3 87130-20-9 single chemical entity Component is identical to the substance Diethofencarb 403-870-3 87130-20-9 isopropyl (3,4-diethoxyphenyl)carbamate Diethofencarb C14H21NO4 O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1 InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Diethofencarb (Revised additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb 20Sep2010 2010 doi:10.2903/j.efsa.2010.1721
+Diethofencarb 403-870-3 87130-20-9 single chemical entity Component is identical to the substance Diethofencarb 403-870-3 87130-20-9 isopropyl (3,4-diethoxyphenyl)carbamate Diethofencarb C14H21NO4 O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1 InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Diethofencarb (Revised additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb 20Sep2010 2010 doi:10.2903/j.efsa.2010.1721
+Diethofencarb 403-870-3 87130-20-9 single chemical entity Component is identical to the substance Diethofencarb 403-870-3 87130-20-9 isopropyl (3,4-diethoxyphenyl)carbamate Diethofencarb C14H21NO4 O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1 InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Diethofencarb (Revised additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb 20Sep2010 2010 doi:10.2903/j.efsa.2010.1721
+Diethofencarb 403-870-3 87130-20-9 single chemical entity Component is identical to the substance Diethofencarb 403-870-3 87130-20-9 isopropyl (3,4-diethoxyphenyl)carbamate Diethofencarb C14H21NO4 O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1 InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Diethofencarb (Revised additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb 20Sep2010 2010 doi:10.2903/j.efsa.2010.1721
+Diethofencarb 403-870-3 87130-20-9 single chemical entity Component is identical to the substance Diethofencarb 403-870-3 87130-20-9 isopropyl (3,4-diethoxyphenyl)carbamate Diethofencarb C14H21NO4 O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1 InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Diethofencarb (Revised additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb 20Sep2010 2010 doi:10.2903/j.efsa.2010.1721
+Diethofencarb 403-870-3 87130-20-9 single chemical entity Component is identical to the substance Diethofencarb 403-870-3 87130-20-9 isopropyl (3,4-diethoxyphenyl)carbamate Diethofencarb C14H21NO4 O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1 InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Diethofencarb (Revised additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb 20Sep2010 2010 doi:10.2903/j.efsa.2010.1721
+Diethofencarb 403-870-3 87130-20-9 single chemical entity Component is identical to the substance Diethofencarb 403-870-3 87130-20-9 isopropyl (3,4-diethoxyphenyl)carbamate Diethofencarb C14H21NO4 O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1 InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: France Diethofencarb (Revised additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb 20Sep2010 2010 doi:10.2903/j.efsa.2010.1721
+Diethofencarb 403-870-3 87130-20-9 single chemical entity Component is identical to the substance Diethofencarb 403-870-3 87130-20-9 isopropyl (3,4-diethoxyphenyl)carbamate Diethofencarb C14H21NO4 O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1 InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: France Diethofencarb (Revised additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb 20Sep2010 2010 doi:10.2903/j.efsa.2010.1721
+Diethofencarb 403-870-3 87130-20-9 single chemical entity Component is identical to the substance Diethofencarb 403-870-3 87130-20-9 isopropyl (3,4-diethoxyphenyl)carbamate Diethofencarb C14H21NO4 O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1 InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Diethofencarb (Revised additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb 20Sep2010 2010 doi:10.2903/j.efsa.2010.1721
+Diethofencarb 403-870-3 87130-20-9 single chemical entity Component is identical to the substance Diethofencarb 403-870-3 87130-20-9 isopropyl (3,4-diethoxyphenyl)carbamate Diethofencarb C14H21NO4 O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1 InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Diethofencarb (Revised additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb 20Sep2010 2010 doi:10.2903/j.efsa.2010.1721
+Diethofencarb 403-870-3 87130-20-9 single chemical entity Component is identical to the substance Diethofencarb 403-870-3 87130-20-9 isopropyl (3,4-diethoxyphenyl)carbamate Diethofencarb C14H21NO4 O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1 InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Diethofencarb (Revised additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb 20Sep2010 2010 doi:10.2903/j.efsa.2010.1721
+Diethofencarb 403-870-3 87130-20-9 single chemical entity Component is identical to the substance Diethofencarb 403-870-3 87130-20-9 isopropyl (3,4-diethoxyphenyl)carbamate Diethofencarb C14H21NO4 O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1 InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: France Diethofencarb (Revised additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb 20Sep2010 2010 doi:10.2903/j.efsa.2010.1721
+Diethofencarb 403-870-3 87130-20-9 single chemical entity Component is identical to the substance Diethofencarb 403-870-3 87130-20-9 isopropyl (3,4-diethoxyphenyl)carbamate Diethofencarb C14H21NO4 O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1 InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: France Diethofencarb (Revised additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb 20Sep2010 2010 doi:10.2903/j.efsa.2010.1721
+Diethofencarb 403-870-3 87130-20-9 single chemical entity Component is identical to the substance Diethofencarb 403-870-3 87130-20-9 isopropyl (3,4-diethoxyphenyl)carbamate Diethofencarb C14H21NO4 O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1 InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: France Diethofencarb (Revised additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb 20Sep2010 2010 doi:10.2903/j.efsa.2010.1721
+Diethofencarb 403-870-3 87130-20-9 single chemical entity Component is identical to the substance Diethofencarb 403-870-3 87130-20-9 isopropyl (3,4-diethoxyphenyl)carbamate Diethofencarb C14H21NO4 O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1 InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: France Diethofencarb (Revised additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb 20Sep2010 2010 doi:10.2903/j.efsa.2010.1721
+Diethofencarb 403-870-3 87130-20-9 single chemical entity Component is identical to the substance Diethofencarb 403-870-3 87130-20-9 isopropyl (3,4-diethoxyphenyl)carbamate Diethofencarb C14H21NO4 O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1 InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: France Diethofencarb (Revised additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb 20Sep2010 2010 doi:10.2903/j.efsa.2010.1721
+Diethofencarb 403-870-3 87130-20-9 single chemical entity Component is identical to the substance Diethofencarb 403-870-3 87130-20-9 isopropyl (3,4-diethoxyphenyl)carbamate Diethofencarb C14H21NO4 O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1 InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: France Diethofencarb (Revised additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb 20Sep2010 2010 doi:10.2903/j.efsa.2010.1721
+Diethofencarb 403-870-3 87130-20-9 single chemical entity Component is identical to the substance Diethofencarb 403-870-3 87130-20-9 isopropyl (3,4-diethoxyphenyl)carbamate Diethofencarb C14H21NO4 O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1 InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16) organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro According to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: France Diethofencarb (Revised additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb 20Sep2010 2010 doi:10.2903/j.efsa.2010.1721
+Diethofencarb 403-870-3 87130-20-9 single chemical entity Component is identical to the substance Diethofencarb 403-870-3 87130-20-9 isopropyl (3,4-diethoxyphenyl)carbamate Diethofencarb C14H21NO4 O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1 InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16) organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro According to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: France Diethofencarb (Revised additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb 20Sep2010 2010 doi:10.2903/j.efsa.2010.1721
+Diethofencarb 403-870-3 87130-20-9 single chemical entity Component is identical to the substance Diethofencarb 403-870-3 87130-20-9 isopropyl (3,4-diethoxyphenyl)carbamate Diethofencarb C14H21NO4 O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1 InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) ICR 6 Male intraperitoneal 72.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity RMS: France Diethofencarb (Revised additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb 20Sep2010 2010 doi:10.2903/j.efsa.2010.1721
+Diethofencarb 403-870-3 87130-20-9 single chemical entity Component is identical to the substance Diethofencarb 403-870-3 87130-20-9 isopropyl (3,4-diethoxyphenyl)carbamate Diethofencarb C14H21NO4 O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1 InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) ICR 6 Male intraperitoneal 48.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity RMS: France Diethofencarb (Revised additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb 20Sep2010 2010 doi:10.2903/j.efsa.2010.1721
+Diethofencarb 403-870-3 87130-20-9 single chemical entity Component is identical to the substance Diethofencarb 403-870-3 87130-20-9 isopropyl (3,4-diethoxyphenyl)carbamate Diethofencarb C14H21NO4 O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1 InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) ICR 6 Male intraperitoneal 24.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity RMS: France Diethofencarb (Revised additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb 20Sep2010 2010 doi:10.2903/j.efsa.2010.1721
+Etofenprox 407-980-2 80844-07-1 single chemical entity Component is identical to the substance Etofenprox 407-980-2 80844-07-1 1-Ethoxy-4-[2-methyl-1-[(3-phenoxyphenyl)methoxy]propan-2-yl]benzene Etofenprox C25H28O3 CCOC1=CC=C(C=C1)C(C)(C)COCC2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C25H28O3/c1-4-27-22-15-13-21(14-16-22)25(2,3)19-26-18-20-9-8-12-24(17-20)28-23-10-6-5-7-11-23/h5-17H,4,18-19H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Italy Etofenprox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox 01Apr2009 2009 doi:10.2903/j.efsa.2009.213r
+Etofenprox 407-980-2 80844-07-1 single chemical entity Component is identical to the substance Etofenprox 407-980-2 80844-07-1 1-Ethoxy-4-[2-methyl-1-[(3-phenoxyphenyl)methoxy]propan-2-yl]benzene Etofenprox C25H28O3 CCOC1=CC=C(C=C1)C(C)(C)COCC2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C25H28O3/c1-4-27-22-15-13-21(14-16-22)25(2,3)19-26-18-20-9-8-12-24(17-20)28-23-10-6-5-7-11-23/h5-17H,4,18-19H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Italy Etofenprox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox 01Apr2009 2009 doi:10.2903/j.efsa.2009.213r
+Etofenprox 407-980-2 80844-07-1 single chemical entity Component is identical to the substance Etofenprox 407-980-2 80844-07-1 1-Ethoxy-4-[2-methyl-1-[(3-phenoxyphenyl)methoxy]propan-2-yl]benzene Etofenprox C25H28O3 CCOC1=CC=C(C=C1)C(C)(C)COCC2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C25H28O3/c1-4-27-22-15-13-21(14-16-22)25(2,3)19-26-18-20-9-8-12-24(17-20)28-23-10-6-5-7-11-23/h5-17H,4,18-19H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: Italy Etofenprox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox 01Apr2009 2009 doi:10.2903/j.efsa.2009.213r
+Etofenprox 407-980-2 80844-07-1 single chemical entity Component is identical to the substance Etofenprox 407-980-2 80844-07-1 1-Ethoxy-4-[2-methyl-1-[(3-phenoxyphenyl)methoxy]propan-2-yl]benzene Etofenprox C25H28O3 CCOC1=CC=C(C=C1)C(C)(C)COCC2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C25H28O3/c1-4-27-22-15-13-21(14-16-22)25(2,3)19-26-18-20-9-8-12-24(17-20)28-23-10-6-5-7-11-23/h5-17H,4,18-19H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: Italy Etofenprox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox 01Apr2009 2009 doi:10.2903/j.efsa.2009.213r
+Etofenprox 407-980-2 80844-07-1 single chemical entity Component is identical to the substance Etofenprox 407-980-2 80844-07-1 1-Ethoxy-4-[2-methyl-1-[(3-phenoxyphenyl)methoxy]propan-2-yl]benzene Etofenprox C25H28O3 CCOC1=CC=C(C=C1)C(C)(C)COCC2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C25H28O3/c1-4-27-22-15-13-21(14-16-22)25(2,3)19-26-18-20-9-8-12-24(17-20)28-23-10-6-5-7-11-23/h5-17H,4,18-19H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Italy Etofenprox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox 01Apr2009 2009 doi:10.2903/j.efsa.2009.213r
+Etofenprox 407-980-2 80844-07-1 single chemical entity Component is identical to the substance Etofenprox 407-980-2 80844-07-1 1-Ethoxy-4-[2-methyl-1-[(3-phenoxyphenyl)methoxy]propan-2-yl]benzene Etofenprox C25H28O3 CCOC1=CC=C(C=C1)C(C)(C)COCC2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C25H28O3/c1-4-27-22-15-13-21(14-16-22)25(2,3)19-26-18-20-9-8-12-24(17-20)28-23-10-6-5-7-11-23/h5-17H,4,18-19H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Italy Etofenprox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox 01Apr2009 2009 doi:10.2903/j.efsa.2009.213r
+Etofenprox 407-980-2 80844-07-1 single chemical entity Component is identical to the substance Etofenprox 407-980-2 80844-07-1 1-Ethoxy-4-[2-methyl-1-[(3-phenoxyphenyl)methoxy]propan-2-yl]benzene Etofenprox C25H28O3 CCOC1=CC=C(C=C1)C(C)(C)COCC2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C25H28O3/c1-4-27-22-15-13-21(14-16-22)25(2,3)19-26-18-20-9-8-12-24(17-20)28-23-10-6-5-7-11-23/h5-17H,4,18-19H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Italy Etofenprox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox 01Apr2009 2009 doi:10.2903/j.efsa.2009.213r
+Etofenprox 407-980-2 80844-07-1 single chemical entity Component is identical to the substance Etofenprox 407-980-2 80844-07-1 1-Ethoxy-4-[2-methyl-1-[(3-phenoxyphenyl)methoxy]propan-2-yl]benzene Etofenprox C25H28O3 CCOC1=CC=C(C=C1)C(C)(C)COCC2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C25H28O3/c1-4-27-22-15-13-21(14-16-22)25(2,3)19-26-18-20-9-8-12-24(17-20)28-23-10-6-5-7-11-23/h5-17H,4,18-19H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Italy Etofenprox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox 01Apr2009 2009 doi:10.2903/j.efsa.2009.213r
+Etofenprox 407-980-2 80844-07-1 single chemical entity Component is identical to the substance Etofenprox 407-980-2 80844-07-1 1-Ethoxy-4-[2-methyl-1-[(3-phenoxyphenyl)methoxy]propan-2-yl]benzene Etofenprox C25H28O3 CCOC1=CC=C(C=C1)C(C)(C)COCC2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C25H28O3/c1-4-27-22-15-13-21(14-16-22)25(2,3)19-26-18-20-9-8-12-24(17-20)28-23-10-6-5-7-11-23/h5-17H,4,18-19H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Italy Etofenprox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox 01Apr2009 2009 doi:10.2903/j.efsa.2009.213r
+Etofenprox 407-980-2 80844-07-1 single chemical entity Component is identical to the substance Etofenprox 407-980-2 80844-07-1 1-Ethoxy-4-[2-methyl-1-[(3-phenoxyphenyl)methoxy]propan-2-yl]benzene Etofenprox C25H28O3 CCOC1=CC=C(C=C1)C(C)(C)COCC2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C25H28O3/c1-4-27-22-15-13-21(14-16-22)25(2,3)19-26-18-20-9-8-12-24(17-20)28-23-10-6-5-7-11-23/h5-17H,4,18-19H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Italy Etofenprox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox 01Apr2009 2009 doi:10.2903/j.efsa.2009.213r
+Etofenprox 407-980-2 80844-07-1 single chemical entity Component is identical to the substance Etofenprox 407-980-2 80844-07-1 1-Ethoxy-4-[2-methyl-1-[(3-phenoxyphenyl)methoxy]propan-2-yl]benzene Etofenprox C25H28O3 CCOC1=CC=C(C=C1)C(C)(C)COCC2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C25H28O3/c1-4-27-22-15-13-21(14-16-22)25(2,3)19-26-18-20-9-8-12-24(17-20)28-23-10-6-5-7-11-23/h5-17H,4,18-19H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Italy Etofenprox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox 01Apr2009 2009 doi:10.2903/j.efsa.2009.213r
+Etofenprox 407-980-2 80844-07-1 single chemical entity Component is identical to the substance Etofenprox 407-980-2 80844-07-1 1-Ethoxy-4-[2-methyl-1-[(3-phenoxyphenyl)methoxy]propan-2-yl]benzene Etofenprox C25H28O3 CCOC1=CC=C(C=C1)C(C)(C)COCC2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C25H28O3/c1-4-27-22-15-13-21(14-16-22)25(2,3)19-26-18-20-9-8-12-24(17-20)28-23-10-6-5-7-11-23/h5-17H,4,18-19H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Italy Etofenprox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox 01Apr2009 2009 doi:10.2903/j.efsa.2009.213r
+Etofenprox 407-980-2 80844-07-1 single chemical entity Component is identical to the substance Etofenprox 407-980-2 80844-07-1 1-Ethoxy-4-[2-methyl-1-[(3-phenoxyphenyl)methoxy]propan-2-yl]benzene Etofenprox C25H28O3 CCOC1=CC=C(C=C1)C(C)(C)COCC2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C25H28O3/c1-4-27-22-15-13-21(14-16-22)25(2,3)19-26-18-20-9-8-12-24(17-20)28-23-10-6-5-7-11-23/h5-17H,4,18-19H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: Italy Etofenprox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox 01Apr2009 2009 doi:10.2903/j.efsa.2009.213r
+Etofenprox 407-980-2 80844-07-1 single chemical entity Component is identical to the substance Etofenprox 407-980-2 80844-07-1 1-Ethoxy-4-[2-methyl-1-[(3-phenoxyphenyl)methoxy]propan-2-yl]benzene Etofenprox C25H28O3 CCOC1=CC=C(C=C1)C(C)(C)COCC2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C25H28O3/c1-4-27-22-15-13-21(14-16-22)25(2,3)19-26-18-20-9-8-12-24(17-20)28-23-10-6-5-7-11-23/h5-17H,4,18-19H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: Italy Etofenprox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox 01Apr2009 2009 doi:10.2903/j.efsa.2009.213r
+Etofenprox 407-980-2 80844-07-1 single chemical entity Component is identical to the substance Etofenprox 407-980-2 80844-07-1 1-Ethoxy-4-[2-methyl-1-[(3-phenoxyphenyl)methoxy]propan-2-yl]benzene Etofenprox C25H28O3 CCOC1=CC=C(C=C1)C(C)(C)COCC2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C25H28O3/c1-4-27-22-15-13-21(14-16-22)25(2,3)19-26-18-20-9-8-12-24(17-20)28-23-10-6-5-7-11-23/h5-17H,4,18-19H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Human (as organism) HeLa cells Not reported yes, concurrent vehicle without Negative RMS: Italy Etofenprox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox 01Apr2009 2009 doi:10.2903/j.efsa.2009.213r
+Etofenprox 407-980-2 80844-07-1 single chemical entity Component is identical to the substance Etofenprox 407-980-2 80844-07-1 1-Ethoxy-4-[2-methyl-1-[(3-phenoxyphenyl)methoxy]propan-2-yl]benzene Etofenprox C25H28O3 CCOC1=CC=C(C=C1)C(C)(C)COCC2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C25H28O3/c1-4-27-22-15-13-21(14-16-22)25(2,3)19-26-18-20-9-8-12-24(17-20)28-23-10-6-5-7-11-23/h5-17H,4,18-19H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Human (as organism) HeLa cells Not reported yes, concurrent vehicle with Negative RMS: Italy Etofenprox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox 01Apr2009 2009 doi:10.2903/j.efsa.2009.213r
+Etofenprox 407-980-2 80844-07-1 single chemical entity Component is identical to the substance Etofenprox 407-980-2 80844-07-1 1-Ethoxy-4-[2-methyl-1-[(3-phenoxyphenyl)methoxy]propan-2-yl]benzene Etofenprox C25H28O3 CCOC1=CC=C(C=C1)C(C)(C)COCC2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C25H28O3/c1-4-27-22-15-13-21(14-16-22)25(2,3)19-26-18-20-9-8-12-24(17-20)28-23-10-6-5-7-11-23/h5-17H,4,18-19H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Italy Etofenprox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox 01Apr2009 2009 doi:10.2903/j.efsa.2009.213r
+Etofenprox 407-980-2 80844-07-1 single chemical entity Component is identical to the substance Etofenprox 407-980-2 80844-07-1 1-Ethoxy-4-[2-methyl-1-[(3-phenoxyphenyl)methoxy]propan-2-yl]benzene Etofenprox C25H28O3 CCOC1=CC=C(C=C1)C(C)(C)COCC2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C25H28O3/c1-4-27-22-15-13-21(14-16-22)25(2,3)19-26-18-20-9-8-12-24(17-20)28-23-10-6-5-7-11-23/h5-17H,4,18-19H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Italy Etofenprox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox 01Apr2009 2009 doi:10.2903/j.efsa.2009.213r
+Etofenprox 407-980-2 80844-07-1 single chemical entity Component is identical to the substance Etofenprox 407-980-2 80844-07-1 1-Ethoxy-4-[2-methyl-1-[(3-phenoxyphenyl)methoxy]propan-2-yl]benzene Etofenprox C25H28O3 CCOC1=CC=C(C=C1)C(C)(C)COCC2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C25H28O3/c1-4-27-22-15-13-21(14-16-22)25(2,3)19-26-18-20-9-8-12-24(17-20)28-23-10-6-5-7-11-23/h5-17H,4,18-19H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 72.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Italy Etofenprox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox 01Apr2009 2009 doi:10.2903/j.efsa.2009.213r
+Etofenprox 407-980-2 80844-07-1 single chemical entity Component is a metabolite of the substance 2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate 117252-00-3 [2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate Not in list C25H26O4 CCOC1=CC=C(C=C1)C©©COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Italy Etofenprox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox 01Apr2009 2009 doi:10.2903/j.efsa.2009.213r
+Etofenprox 407-980-2 80844-07-1 single chemical entity Component is a metabolite of the substance 2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate 117252-00-3 [2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate Not in list C25H26O4 CCOC1=CC=C(C=C1)C©©COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Italy Etofenprox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox 01Apr2009 2009 doi:10.2903/j.efsa.2009.213r
+Etofenprox 407-980-2 80844-07-1 single chemical entity Component is a metabolite of the substance 2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate 117252-00-3 [2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate Not in list C25H26O4 CCOC1=CC=C(C=C1)C©©COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: Italy Etofenprox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox 01Apr2009 2009 doi:10.2903/j.efsa.2009.213r
+Etofenprox 407-980-2 80844-07-1 single chemical entity Component is a metabolite of the substance 2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate 117252-00-3 [2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate Not in list C25H26O4 CCOC1=CC=C(C=C1)C©©COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes with Negative RMS: Italy Etofenprox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox 01Apr2009 2009 doi:10.2903/j.efsa.2009.213r
+Etofenprox 407-980-2 80844-07-1 single chemical entity Component is a metabolite of the substance 2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate 117252-00-3 [2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate Not in list C25H26O4 CCOC1=CC=C(C=C1)C©©COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Italy Etofenprox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox 01Apr2009 2009 doi:10.2903/j.efsa.2009.213r
+Etofenprox 407-980-2 80844-07-1 single chemical entity Component is a metabolite of the substance 2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate 117252-00-3 [2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate Not in list C25H26O4 CCOC1=CC=C(C=C1)C©©COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Italy Etofenprox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox 01Apr2009 2009 doi:10.2903/j.efsa.2009.213r
+Etofenprox 407-980-2 80844-07-1 single chemical entity Component is a metabolite of the substance 2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate 117252-00-3 [2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate Not in list C25H26O4 CCOC1=CC=C(C=C1)C©©COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes without Negative RMS: Italy Etofenprox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox 01Apr2009 2009 doi:10.2903/j.efsa.2009.213r
+Etofenprox 407-980-2 80844-07-1 single chemical entity Component is a metabolite of the substance 2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate 117252-00-3 [2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate Not in list C25H26O4 CCOC1=CC=C(C=C1)C©©COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Italy Etofenprox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox 01Apr2009 2009 doi:10.2903/j.efsa.2009.213r
+Etofenprox 407-980-2 80844-07-1 single chemical entity Component is a metabolite of the substance 2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate 117252-00-3 [2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate Not in list C25H26O4 CCOC1=CC=C(C=C1)C©©COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Italy Etofenprox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox 01Apr2009 2009 doi:10.2903/j.efsa.2009.213r
+Etofenprox 407-980-2 80844-07-1 single chemical entity Component is a metabolite of the substance 2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate 117252-00-3 [2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate Not in list C25H26O4 CCOC1=CC=C(C=C1)C©©COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes with Negative RMS: Italy Etofenprox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox 01Apr2009 2009 doi:10.2903/j.efsa.2009.213r
+Etofenprox 407-980-2 80844-07-1 single chemical entity Component is a metabolite of the substance 2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate 117252-00-3 [2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate Not in list C25H26O4 CCOC1=CC=C(C=C1)C©©COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Italy Etofenprox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox 01Apr2009 2009 doi:10.2903/j.efsa.2009.213r
+Etofenprox 407-980-2 80844-07-1 single chemical entity Component is a metabolite of the substance 2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate 117252-00-3 [2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate Not in list C25H26O4 CCOC1=CC=C(C=C1)C©©COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes without Negative RMS: Italy Etofenprox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox 01Apr2009 2009 doi:10.2903/j.efsa.2009.213r
+Etofenprox 407-980-2 80844-07-1 single chemical entity Component is a metabolite of the substance 2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate 117252-00-3 [2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate Not in list C25H26O4 CCOC1=CC=C(C=C1)C©©COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Italy Etofenprox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox 01Apr2009 2009 doi:10.2903/j.efsa.2009.213r
+Etofenprox 407-980-2 80844-07-1 single chemical entity Component is a metabolite of the substance 2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate 117252-00-3 [2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate Not in list C25H26O4 CCOC1=CC=C(C=C1)C©©COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: Italy Etofenprox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox 01Apr2009 2009 doi:10.2903/j.efsa.2009.213r
+Etofenprox 407-980-2 80844-07-1 single chemical entity Component is a metabolite of the substance 2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate 117252-00-3 [2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate Not in list C25H26O4 CCOC1=CC=C(C=C1)C©©COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) CM871 Not reported yes, concurrent vehicle with Negative RMS: Italy Etofenprox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox 01Apr2009 2009 doi:10.2903/j.efsa.2009.213r
+Etofenprox 407-980-2 80844-07-1 single chemical entity Component is a metabolite of the substance 2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate 117252-00-3 [2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate Not in list C25H26O4 CCOC1=CC=C(C=C1)C©©COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) CM871 Not reported yes, concurrent vehicle without Negative RMS: Italy Etofenprox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox 01Apr2009 2009 doi:10.2903/j.efsa.2009.213r
+Etofenprox 407-980-2 80844-07-1 single chemical entity Component is a metabolite of the substance 2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate 117252-00-3 [2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate Not in list C25H26O4 CCOC1=CC=C(C=C1)C©©COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) WP67 Not reported yes, concurrent vehicle without Negative RMS: Italy Etofenprox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox 01Apr2009 2009 doi:10.2903/j.efsa.2009.213r
+Etofenprox 407-980-2 80844-07-1 single chemical entity Component is a metabolite of the substance 2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate 117252-00-3 [2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate Not in list C25H26O4 CCOC1=CC=C(C=C1)C©©COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) WP67 Not reported yes, concurrent vehicle with Negative RMS: Italy Etofenprox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox 01Apr2009 2009 doi:10.2903/j.efsa.2009.213r
+Etofenprox 407-980-2 80844-07-1 single chemical entity Component is a metabolite of the substance 2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate 117252-00-3 [2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate Not in list C25H26O4 CCOC1=CC=C(C=C1)C©©COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle without Negative RMS: Italy Etofenprox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox 01Apr2009 2009 doi:10.2903/j.efsa.2009.213r
+Etofenprox 407-980-2 80844-07-1 single chemical entity Component is a metabolite of the substance 2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate 117252-00-3 [2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate Not in list C25H26O4 CCOC1=CC=C(C=C1)C©©COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle with Negative RMS: Italy Etofenprox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox 01Apr2009 2009 doi:10.2903/j.efsa.2009.213r
+Etofenprox 407-980-2 80844-07-1 single chemical entity Component is a metabolite of the substance 2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate 117252-00-3 [2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate Not in list C25H26O4 CCOC1=CC=C(C=C1)C©©COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes without Negative RMS: Italy Etofenprox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox 01Apr2009 2009 doi:10.2903/j.efsa.2009.213r
+Etofenprox 407-980-2 80844-07-1 single chemical entity Component is a metabolite of the substance 2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate 117252-00-3 [2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate Not in list C25H26O4 CCOC1=CC=C(C=C1)C©©COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3 InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes with Negative RMS: Italy Etofenprox 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox 01Apr2009 2009 doi:10.2903/j.efsa.2009.213r
+Dimoxystrobin 149961-52-4 single chemical entity Component is identical to the substance Dimoxystrobin 149961-52-4 (2Z)-2-[2-[(2,5-dimethylphenoxy)methyl]phenyl]-2-methoxyimino-N-methylacetamide Dimoxystrobin C19H22N2O3 CC1=CC(=C(C=C1)C)OCC2=CC=CC=C2C(=NOC)C(=O)NC InChI=1S/C19H22N2O3/c1-13-9-10-14(2)17(11-13)24-12-15-7-5-6-8-16(15)18(21-23-4)19(22)20-3/h5-11H,12H2,1-4H3,(H,20,22)/b21-18- organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Dimoxystrobin 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.46r
+Dimoxystrobin 149961-52-4 single chemical entity Component is identical to the substance Dimoxystrobin 149961-52-4 (2Z)-2-[2-[(2,5-dimethylphenoxy)methyl]phenyl]-2-methoxyimino-N-methylacetamide Dimoxystrobin C19H22N2O3 CC1=CC(=C(C=C1)C)OCC2=CC=CC=C2C(=NOC)C(=O)NC InChI=1S/C19H22N2O3/c1-13-9-10-14(2)17(11-13)24-12-15-7-5-6-8-16(15)18(21-23-4)19(22)20-3/h5-11H,12H2,1-4H3,(H,20,22)/b21-18- organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Dimoxystrobin 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.46r
+Dimoxystrobin 149961-52-4 single chemical entity Component is identical to the substance Dimoxystrobin 149961-52-4 (2Z)-2-[2-[(2,5-dimethylphenoxy)methyl]phenyl]-2-methoxyimino-N-methylacetamide Dimoxystrobin C19H22N2O3 CC1=CC(=C(C=C1)C)OCC2=CC=CC=C2C(=NOC)C(=O)NC InChI=1S/C19H22N2O3/c1-13-9-10-14(2)17(11-13)24-12-15-7-5-6-8-16(15)18(21-23-4)19(22)20-3/h5-11H,12H2,1-4H3,(H,20,22)/b21-18- organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Dimoxystrobin 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.46r
+Dimoxystrobin 149961-52-4 single chemical entity Component is identical to the substance Dimoxystrobin 149961-52-4 (2Z)-2-[2-[(2,5-dimethylphenoxy)methyl]phenyl]-2-methoxyimino-N-methylacetamide Dimoxystrobin C19H22N2O3 CC1=CC(=C(C=C1)C)OCC2=CC=CC=C2C(=NOC)C(=O)NC InChI=1S/C19H22N2O3/c1-13-9-10-14(2)17(11-13)24-12-15-7-5-6-8-16(15)18(21-23-4)19(22)20-3/h5-11H,12H2,1-4H3,(H,20,22)/b21-18- organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Dimoxystrobin 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.46r
+Dimoxystrobin 149961-52-4 single chemical entity Component is identical to the substance Dimoxystrobin 149961-52-4 (2Z)-2-[2-[(2,5-dimethylphenoxy)methyl]phenyl]-2-methoxyimino-N-methylacetamide Dimoxystrobin C19H22N2O3 CC1=CC(=C(C=C1)C)OCC2=CC=CC=C2C(=NOC)C(=O)NC InChI=1S/C19H22N2O3/c1-13-9-10-14(2)17(11-13)24-12-15-7-5-6-8-16(15)18(21-23-4)19(22)20-3/h5-11H,12H2,1-4H3,(H,20,22)/b21-18- organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Dimoxystrobin 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.46r
+Dimoxystrobin 149961-52-4 single chemical entity Component is identical to the substance Dimoxystrobin 149961-52-4 (2Z)-2-[2-[(2,5-dimethylphenoxy)methyl]phenyl]-2-methoxyimino-N-methylacetamide Dimoxystrobin C19H22N2O3 CC1=CC(=C(C=C1)C)OCC2=CC=CC=C2C(=NOC)C(=O)NC InChI=1S/C19H22N2O3/c1-13-9-10-14(2)17(11-13)24-12-15-7-5-6-8-16(15)18(21-23-4)19(22)20-3/h5-11H,12H2,1-4H3,(H,20,22)/b21-18- organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Dimoxystrobin 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.46r
+Dimoxystrobin 149961-52-4 single chemical entity Component is identical to the substance Dimoxystrobin 149961-52-4 (2Z)-2-[2-[(2,5-dimethylphenoxy)methyl]phenyl]-2-methoxyimino-N-methylacetamide Dimoxystrobin C19H22N2O3 CC1=CC(=C(C=C1)C)OCC2=CC=CC=C2C(=NOC)C(=O)NC InChI=1S/C19H22N2O3/c1-13-9-10-14(2)17(11-13)24-12-15-7-5-6-8-16(15)18(21-23-4)19(22)20-3/h5-11H,12H2,1-4H3,(H,20,22)/b21-18- organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Dimoxystrobin 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.46r
+Dimoxystrobin 149961-52-4 single chemical entity Component is identical to the substance Dimoxystrobin 149961-52-4 (2Z)-2-[2-[(2,5-dimethylphenoxy)methyl]phenyl]-2-methoxyimino-N-methylacetamide Dimoxystrobin C19H22N2O3 CC1=CC(=C(C=C1)C)OCC2=CC=CC=C2C(=NOC)C(=O)NC InChI=1S/C19H22N2O3/c1-13-9-10-14(2)17(11-13)24-12-15-7-5-6-8-16(15)18(21-23-4)19(22)20-3/h5-11H,12H2,1-4H3,(H,20,22)/b21-18- organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Dimoxystrobin 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.46r
+Dimoxystrobin 149961-52-4 single chemical entity Component is identical to the substance Dimoxystrobin 149961-52-4 (2Z)-2-[2-[(2,5-dimethylphenoxy)methyl]phenyl]-2-methoxyimino-N-methylacetamide Dimoxystrobin C19H22N2O3 CC1=CC(=C(C=C1)C)OCC2=CC=CC=C2C(=NOC)C(=O)NC InChI=1S/C19H22N2O3/c1-13-9-10-14(2)17(11-13)24-12-15-7-5-6-8-16(15)18(21-23-4)19(22)20-3/h5-11H,12H2,1-4H3,(H,20,22)/b21-18- organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Dimoxystrobin 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.46r
+Dimoxystrobin 149961-52-4 single chemical entity Component is identical to the substance Dimoxystrobin 149961-52-4 (2Z)-2-[2-[(2,5-dimethylphenoxy)methyl]phenyl]-2-methoxyimino-N-methylacetamide Dimoxystrobin C19H22N2O3 CC1=CC(=C(C=C1)C)OCC2=CC=CC=C2C(=NOC)C(=O)NC InChI=1S/C19H22N2O3/c1-13-9-10-14(2)17(11-13)24-12-15-7-5-6-8-16(15)18(21-23-4)19(22)20-3/h5-11H,12H2,1-4H3,(H,20,22)/b21-18- organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Dimoxystrobin 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.46r
+Dimoxystrobin 149961-52-4 single chemical entity Component is identical to the substance Dimoxystrobin 149961-52-4 (2Z)-2-[2-[(2,5-dimethylphenoxy)methyl]phenyl]-2-methoxyimino-N-methylacetamide Dimoxystrobin C19H22N2O3 CC1=CC(=C(C=C1)C)OCC2=CC=CC=C2C(=NOC)C(=O)NC InChI=1S/C19H22N2O3/c1-13-9-10-14(2)17(11-13)24-12-15-7-5-6-8-16(15)18(21-23-4)19(22)20-3/h5-11H,12H2,1-4H3,(H,20,22)/b21-18- organic compound PubChem isomeric SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: The United Kingdom Dimoxystrobin 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.46r
+Dimoxystrobin 149961-52-4 single chemical entity Component is identical to the substance Dimoxystrobin 149961-52-4 (2Z)-2-[2-[(2,5-dimethylphenoxy)methyl]phenyl]-2-methoxyimino-N-methylacetamide Dimoxystrobin C19H22N2O3 CC1=CC(=C(C=C1)C)OCC2=CC=CC=C2C(=NOC)C(=O)NC InChI=1S/C19H22N2O3/c1-13-9-10-14(2)17(11-13)24-12-15-7-5-6-8-16(15)18(21-23-4)19(22)20-3/h5-11H,12H2,1-4H3,(H,20,22)/b21-18- organic compound PubChem isomeric SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: The United Kingdom Dimoxystrobin 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.46r
+Dimoxystrobin 149961-52-4 single chemical entity Component is identical to the substance Dimoxystrobin 149961-52-4 (2Z)-2-[2-[(2,5-dimethylphenoxy)methyl]phenyl]-2-methoxyimino-N-methylacetamide Dimoxystrobin C19H22N2O3 CC1=CC(=C(C=C1)C)OCC2=CC=CC=C2C(=NOC)C(=O)NC InChI=1S/C19H22N2O3/c1-13-9-10-14(2)17(11-13)24-12-15-7-5-6-8-16(15)18(21-23-4)19(22)20-3/h5-11H,12H2,1-4H3,(H,20,22)/b21-18- organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Dimoxystrobin 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.46r
+Dimoxystrobin 149961-52-4 single chemical entity Component is identical to the substance Dimoxystrobin 149961-52-4 (2Z)-2-[2-[(2,5-dimethylphenoxy)methyl]phenyl]-2-methoxyimino-N-methylacetamide Dimoxystrobin C19H22N2O3 CC1=CC(=C(C=C1)C)OCC2=CC=CC=C2C(=NOC)C(=O)NC InChI=1S/C19H22N2O3/c1-13-9-10-14(2)17(11-13)24-12-15-7-5-6-8-16(15)18(21-23-4)19(22)20-3/h5-11H,12H2,1-4H3,(H,20,22)/b21-18- organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Dimoxystrobin 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.46r
+Dimoxystrobin 149961-52-4 single chemical entity Component is identical to the substance Dimoxystrobin 149961-52-4 (2Z)-2-[2-[(2,5-dimethylphenoxy)methyl]phenyl]-2-methoxyimino-N-methylacetamide Dimoxystrobin C19H22N2O3 CC1=CC(=C(C=C1)C)OCC2=CC=CC=C2C(=NOC)C(=O)NC InChI=1S/C19H22N2O3/c1-13-9-10-14(2)17(11-13)24-12-15-7-5-6-8-16(15)18(21-23-4)19(22)20-3/h5-11H,12H2,1-4H3,(H,20,22)/b21-18- organic compound PubChem isomeric SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes without Negative RMS: The United Kingdom Dimoxystrobin 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.46r
+Dimoxystrobin 149961-52-4 single chemical entity Component is identical to the substance Dimoxystrobin 149961-52-4 (2Z)-2-[2-[(2,5-dimethylphenoxy)methyl]phenyl]-2-methoxyimino-N-methylacetamide Dimoxystrobin C19H22N2O3 CC1=CC(=C(C=C1)C)OCC2=CC=CC=C2C(=NOC)C(=O)NC InChI=1S/C19H22N2O3/c1-13-9-10-14(2)17(11-13)24-12-15-7-5-6-8-16(15)18(21-23-4)19(22)20-3/h5-11H,12H2,1-4H3,(H,20,22)/b21-18- organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity$indirect-toxicokinetic investigations RMS: The United Kingdom Dimoxystrobin 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.46r
+Dimoxystrobin 149961-52-4 single chemical entity Component is identical to the substance Dimoxystrobin 149961-52-4 (2Z)-2-[2-[(2,5-dimethylphenoxy)methyl]phenyl]-2-methoxyimino-N-methylacetamide Dimoxystrobin C19H22N2O3 CC1=CC(=C(C=C1)C)OCC2=CC=CC=C2C(=NOC)C(=O)NC InChI=1S/C19H22N2O3/c1-13-9-10-14(2)17(11-13)24-12-15-7-5-6-8-16(15)18(21-23-4)19(22)20-3/h5-11H,12H2,1-4H3,(H,20,22)/b21-18- organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity$indirect-toxicokinetic investigations RMS: The United Kingdom Dimoxystrobin 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.46r
+Dimoxystrobin 149961-52-4 single chemical entity Component is a metabolite of the substance ((E)-2-(2-hydroxymethylphenyl)-2-methoxyimino-N-methyl-acetamide) (2E)-2-[2-(hydroxymethyl)phenyl]-2-(methoxyimino)-N-methylacetamide Not in list C11H14N2O3 OCc1ccccc1/C(=N\OC)C(=O)NC InChI=1S/C11H14N2O3/c1-12-11(15)10(13-16-2)9-6-4-3-5-8(9)7-14/h3-6,14H,7H2,1-2H3,(H,12,15)/b13-10+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The United Kingdom Dimoxystrobin 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.46r
+Dimoxystrobin 149961-52-4 single chemical entity Component is a metabolite of the substance ((E)-2-(2-hydroxymethylphenyl)-2-methoxyimino-N-methyl-acetamide) (2E)-2-[2-(hydroxymethyl)phenyl]-2-(methoxyimino)-N-methylacetamide Not in list C11H14N2O3 OCc1ccccc1/C(=N\OC)C(=O)NC InChI=1S/C11H14N2O3/c1-12-11(15)10(13-16-2)9-6-4-3-5-8(9)7-14/h3-6,14H,7H2,1-2H3,(H,12,15)/b13-10+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The United Kingdom Dimoxystrobin 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.46r
+Dimoxystrobin 149961-52-4 single chemical entity Component is a metabolite of the substance ((E)-2-(2-hydroxymethylphenyl)-2-methoxyimino-N-methyl-acetamide) (2E)-2-[2-(hydroxymethyl)phenyl]-2-(methoxyimino)-N-methylacetamide Not in list C11H14N2O3 OCc1ccccc1/C(=N\OC)C(=O)NC InChI=1S/C11H14N2O3/c1-12-11(15)10(13-16-2)9-6-4-3-5-8(9)7-14/h3-6,14H,7H2,1-2H3,(H,12,15)/b13-10+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The United Kingdom Dimoxystrobin 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.46r
+Dimoxystrobin 149961-52-4 single chemical entity Component is a metabolite of the substance ((E)-2-(2-hydroxymethylphenyl)-2-methoxyimino-N-methyl-acetamide) (2E)-2-[2-(hydroxymethyl)phenyl]-2-(methoxyimino)-N-methylacetamide Not in list C11H14N2O3 OCc1ccccc1/C(=N\OC)C(=O)NC InChI=1S/C11H14N2O3/c1-12-11(15)10(13-16-2)9-6-4-3-5-8(9)7-14/h3-6,14H,7H2,1-2H3,(H,12,15)/b13-10+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The United Kingdom Dimoxystrobin 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.46r
+Dimoxystrobin 149961-52-4 single chemical entity Component is a metabolite of the substance ((E)-2-(2-hydroxymethylphenyl)-2-methoxyimino-N-methyl-acetamide) (2E)-2-[2-(hydroxymethyl)phenyl]-2-(methoxyimino)-N-methylacetamide Not in list C11H14N2O3 OCc1ccccc1/C(=N\OC)C(=O)NC InChI=1S/C11H14N2O3/c1-12-11(15)10(13-16-2)9-6-4-3-5-8(9)7-14/h3-6,14H,7H2,1-2H3,(H,12,15)/b13-10+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: The United Kingdom Dimoxystrobin 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.46r
+Dimoxystrobin 149961-52-4 single chemical entity Component is a metabolite of the substance ((E)-2-(2-hydroxymethylphenyl)-2-methoxyimino-N-methyl-acetamide) (2E)-2-[2-(hydroxymethyl)phenyl]-2-(methoxyimino)-N-methylacetamide Not in list C11H14N2O3 OCc1ccccc1/C(=N\OC)C(=O)NC InChI=1S/C11H14N2O3/c1-12-11(15)10(13-16-2)9-6-4-3-5-8(9)7-14/h3-6,14H,7H2,1-2H3,(H,12,15)/b13-10+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The United Kingdom Dimoxystrobin 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.46r
+Dimoxystrobin 149961-52-4 single chemical entity Component is a metabolite of the substance ((E)-2-(2-hydroxymethylphenyl)-2-methoxyimino-N-methyl-acetamide) (2E)-2-[2-(hydroxymethyl)phenyl]-2-(methoxyimino)-N-methylacetamide Not in list C11H14N2O3 OCc1ccccc1/C(=N\OC)C(=O)NC InChI=1S/C11H14N2O3/c1-12-11(15)10(13-16-2)9-6-4-3-5-8(9)7-14/h3-6,14H,7H2,1-2H3,(H,12,15)/b13-10+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: The United Kingdom Dimoxystrobin 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.46r
+Dimoxystrobin 149961-52-4 single chemical entity Component is a metabolite of the substance ((E)-2-(2-hydroxymethylphenyl)-2-methoxyimino-N-methyl-acetamide) (2E)-2-[2-(hydroxymethyl)phenyl]-2-(methoxyimino)-N-methylacetamide Not in list C11H14N2O3 OCc1ccccc1/C(=N\OC)C(=O)NC InChI=1S/C11H14N2O3/c1-12-11(15)10(13-16-2)9-6-4-3-5-8(9)7-14/h3-6,14H,7H2,1-2H3,(H,12,15)/b13-10+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The United Kingdom Dimoxystrobin 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.46r
+Dimoxystrobin 149961-52-4 single chemical entity Component is a metabolite of the substance ((E)-2-(2-hydroxymethylphenyl)-2-methoxyimino-N-methyl-acetamide) (2E)-2-[2-(hydroxymethyl)phenyl]-2-(methoxyimino)-N-methylacetamide Not in list C11H14N2O3 OCc1ccccc1/C(=N\OC)C(=O)NC InChI=1S/C11H14N2O3/c1-12-11(15)10(13-16-2)9-6-4-3-5-8(9)7-14/h3-6,14H,7H2,1-2H3,(H,12,15)/b13-10+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The United Kingdom Dimoxystrobin 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.46r
+Dimoxystrobin 149961-52-4 single chemical entity Component is a metabolite of the substance ((E)-2-(2-hydroxymethylphenyl)-2-methoxyimino-N-methyl-acetamide) (2E)-2-[2-(hydroxymethyl)phenyl]-2-(methoxyimino)-N-methylacetamide Not in list C11H14N2O3 OCc1ccccc1/C(=N\OC)C(=O)NC InChI=1S/C11H14N2O3/c1-12-11(15)10(13-16-2)9-6-4-3-5-8(9)7-14/h3-6,14H,7H2,1-2H3,(H,12,15)/b13-10+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The United Kingdom Dimoxystrobin 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.46r
+Dimoxystrobin 149961-52-4 single chemical entity Component is a metabolite of the substance ((E)-2-(2-hydroxymethylphenyl)-2-methoxyimino-N-methyl-acetamide) (2E)-2-[2-(hydroxymethyl)phenyl]-2-(methoxyimino)-N-methylacetamide Not in list C11H14N2O3 OCc1ccccc1/C(=N\OC)C(=O)NC InChI=1S/C11H14N2O3/c1-12-11(15)10(13-16-2)9-6-4-3-5-8(9)7-14/h3-6,14H,7H2,1-2H3,(H,12,15)/b13-10+ organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: The United Kingdom Dimoxystrobin 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.46r
+Dimoxystrobin 149961-52-4 single chemical entity Component is a metabolite of the substance ((E)-2-(2-hydroxymethylphenyl)-2-methoxyimino-N-methyl-acetamide) (2E)-2-[2-(hydroxymethyl)phenyl]-2-(methoxyimino)-N-methylacetamide Not in list C11H14N2O3 OCc1ccccc1/C(=N\OC)C(=O)NC InChI=1S/C11H14N2O3/c1-12-11(15)10(13-16-2)9-6-4-3-5-8(9)7-14/h3-6,14H,7H2,1-2H3,(H,12,15)/b13-10+ organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Negative RMS: The United Kingdom Dimoxystrobin 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.46r
+Dimoxystrobin 149961-52-4 single chemical entity Component is a metabolite of the substance ((E)-2-(2-hydroxymethylphenyl)-2-methoxyimino-N-methyl-acetamide) (2E)-2-[2-(hydroxymethyl)phenyl]-2-(methoxyimino)-N-methylacetamide Not in list C11H14N2O3 OCc1ccccc1/C(=N\OC)C(=O)NC InChI=1S/C11H14N2O3/c1-12-11(15)10(13-16-2)9-6-4-3-5-8(9)7-14/h3-6,14H,7H2,1-2H3,(H,12,15)/b13-10+ organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Negative RMS: The United Kingdom Dimoxystrobin 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.46r
+Dimoxystrobin 149961-52-4 single chemical entity Component is a metabolite of the substance ((E)-2-(2-hydroxymethylphenyl)-2-methoxyimino-N-methyl-acetamide) (2E)-2-[2-(hydroxymethyl)phenyl]-2-(methoxyimino)-N-methylacetamide Not in list C11H14N2O3 OCc1ccccc1/C(=N\OC)C(=O)NC InChI=1S/C11H14N2O3/c1-12-11(15)10(13-16-2)9-6-4-3-5-8(9)7-14/h3-6,14H,7H2,1-2H3,(H,12,15)/b13-10+ organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: The United Kingdom Dimoxystrobin 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.46r
+Disodium phosphonate 237-249-1 13708-85-5 single chemical entity Component is identical to the substance Disodium phosphonate 237-249-1 13708-85-5 Disodium phosphonate Not in list H3O3P.2Na [O-]P(=O)=O.[Na+].[Na+] InChI=1S/2Na.HO3P/c;;1-4(2)3/h;;(H,1,2,3)/q2*+1;/p-1 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: France Disodium phosphonate (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance disodium phosphonate. 31May2013 2013 doi:10.2903/j.efsa.2013.3213
+Disodium phosphonate 237-249-1 13708-85-5 single chemical entity Component is identical to the substance Disodium phosphonate 237-249-1 13708-85-5 Disodium phosphonate Not in list H3O3P.2Na [O-]P(=O)=O.[Na+].[Na+] InChI=1S/2Na.HO3P/c;;1-4(2)3/h;;(H,1,2,3)/q2*+1;/p-1 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: France Disodium phosphonate (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance disodium phosphonate. 31May2013 2013 doi:10.2903/j.efsa.2013.3213
+Disodium phosphonate 237-249-1 13708-85-5 single chemical entity Component is identical to the substance Disodium phosphonate 237-249-1 13708-85-5 Disodium phosphonate Not in list H3O3P.2Na [O-]P(=O)=O.[Na+].[Na+] InChI=1S/2Na.HO3P/c;;1-4(2)3/h;;(H,1,2,3)/q2*+1;/p-1 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: France Disodium phosphonate (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance disodium phosphonate. 31May2013 2013 doi:10.2903/j.efsa.2013.3213
+Disodium phosphonate 237-249-1 13708-85-5 single chemical entity Component is identical to the substance Disodium phosphonate 237-249-1 13708-85-5 Disodium phosphonate Not in list H3O3P.2Na [O-]P(=O)=O.[Na+].[Na+] InChI=1S/2Na.HO3P/c;;1-4(2)3/h;;(H,1,2,3)/q2*+1;/p-1 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: France Disodium phosphonate (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance disodium phosphonate. 31May2013 2013 doi:10.2903/j.efsa.2013.3213
+Disodium phosphonate 237-249-1 13708-85-5 single chemical entity Component is identical to the substance Disodium phosphonate 237-249-1 13708-85-5 Disodium phosphonate Not in list H3O3P.2Na [O-]P(=O)=O.[Na+].[Na+] InChI=1S/2Na.HO3P/c;;1-4(2)3/h;;(H,1,2,3)/q2*+1;/p-1 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: France Disodium phosphonate (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance disodium phosphonate. 31May2013 2013 doi:10.2903/j.efsa.2013.3213
+Disodium phosphonate 237-249-1 13708-85-5 single chemical entity Component is identical to the substance Disodium phosphonate 237-249-1 13708-85-5 Disodium phosphonate Not in list H3O3P.2Na [O-]P(=O)=O.[Na+].[Na+] InChI=1S/2Na.HO3P/c;;1-4(2)3/h;;(H,1,2,3)/q2*+1;/p-1 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: France Disodium phosphonate (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance disodium phosphonate. 31May2013 2013 doi:10.2903/j.efsa.2013.3213
+Disodium phosphonate 237-249-1 13708-85-5 single chemical entity Component is identical to the substance Disodium phosphonate 237-249-1 13708-85-5 Disodium phosphonate Not in list H3O3P.2Na [O-]P(=O)=O.[Na+].[Na+] InChI=1S/2Na.HO3P/c;;1-4(2)3/h;;(H,1,2,3)/q2*+1;/p-1 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: France Disodium phosphonate (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance disodium phosphonate. 31May2013 2013 doi:10.2903/j.efsa.2013.3213
+Disodium phosphonate 237-249-1 13708-85-5 single chemical entity Component is identical to the substance Disodium phosphonate 237-249-1 13708-85-5 Disodium phosphonate Not in list H3O3P.2Na [O-]P(=O)=O.[Na+].[Na+] InChI=1S/2Na.HO3P/c;;1-4(2)3/h;;(H,1,2,3)/q2*+1;/p-1 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: France Disodium phosphonate (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance disodium phosphonate. 31May2013 2013 doi:10.2903/j.efsa.2013.3213
+Disodium phosphonate 237-249-1 13708-85-5 single chemical entity Component is identical to the substance Disodium phosphonate 237-249-1 13708-85-5 Disodium phosphonate Not in list H3O3P.2Na [O-]P(=O)=O.[Na+].[Na+] InChI=1S/2Na.HO3P/c;;1-4(2)3/h;;(H,1,2,3)/q2*+1;/p-1 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: France Disodium phosphonate (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance disodium phosphonate. 31May2013 2013 doi:10.2903/j.efsa.2013.3213
+Disodium phosphonate 237-249-1 13708-85-5 single chemical entity Component is identical to the substance Disodium phosphonate 237-249-1 13708-85-5 Disodium phosphonate Not in list H3O3P.2Na [O-]P(=O)=O.[Na+].[Na+] InChI=1S/2Na.HO3P/c;;1-4(2)3/h;;(H,1,2,3)/q2*+1;/p-1 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: France Disodium phosphonate (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance disodium phosphonate. 31May2013 2013 doi:10.2903/j.efsa.2013.3213
+Disodium phosphonate 237-249-1 13708-85-5 single chemical entity Component is identical to the substance Disodium phosphonate 237-249-1 13708-85-5 Disodium phosphonate Not in list H3O3P.2Na [O-]P(=O)=O.[Na+].[Na+] InChI=1S/2Na.HO3P/c;;1-4(2)3/h;;(H,1,2,3)/q2*+1;/p-1 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: France Disodium phosphonate (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance disodium phosphonate. 31May2013 2013 doi:10.2903/j.efsa.2013.3213
+Disodium phosphonate 237-249-1 13708-85-5 single chemical entity Component is identical to the substance Disodium phosphonate 237-249-1 13708-85-5 Disodium phosphonate Not in list H3O3P.2Na [O-]P(=O)=O.[Na+].[Na+] InChI=1S/2Na.HO3P/c;;1-4(2)3/h;;(H,1,2,3)/q2*+1;/p-1 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: France Disodium phosphonate (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance disodium phosphonate. 31May2013 2013 doi:10.2903/j.efsa.2013.3213
+Disodium phosphonate 237-249-1 13708-85-5 single chemical entity Component is identical to the substance Disodium phosphonate 237-249-1 13708-85-5 Disodium phosphonate Not in list H3O3P.2Na [O-]P(=O)=O.[Na+].[Na+] InChI=1S/2Na.HO3P/c;;1-4(2)3/h;;(H,1,2,3)/q2*+1;/p-1 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 12 Male/Female oral: unspecified 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: France Disodium phosphonate (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance disodium phosphonate. 31May2013 2013 doi:10.2903/j.efsa.2013.3213
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is identical to the substance Bitertanol 259-513-5 55179-31-2 1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Bitertanol C20H23N3O2 CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3 InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is identical to the substance Bitertanol 259-513-5 55179-31-2 1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Bitertanol C20H23N3O2 CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3 InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is identical to the substance Bitertanol 259-513-5 55179-31-2 1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Bitertanol C20H23N3O2 CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3 InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is identical to the substance Bitertanol 259-513-5 55179-31-2 1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Bitertanol C20H23N3O2 CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3 InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is identical to the substance Bitertanol 259-513-5 55179-31-2 1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Bitertanol C20H23N3O2 CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3 InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3 organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes no data Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is identical to the substance Bitertanol 259-513-5 55179-31-2 1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Bitertanol C20H23N3O2 CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3 InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is identical to the substance Bitertanol 259-513-5 55179-31-2 1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Bitertanol C20H23N3O2 CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3 InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is identical to the substance Bitertanol 259-513-5 55179-31-2 1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Bitertanol C20H23N3O2 CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3 InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is identical to the substance Bitertanol 259-513-5 55179-31-2 1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Bitertanol C20H23N3O2 CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3 InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is identical to the substance Bitertanol 259-513-5 55179-31-2 1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Bitertanol C20H23N3O2 CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3 InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is identical to the substance Bitertanol 259-513-5 55179-31-2 1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Bitertanol C20H23N3O2 CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3 InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3 organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes no data Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is identical to the substance Bitertanol 259-513-5 55179-31-2 1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Bitertanol C20H23N3O2 CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3 InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is identical to the substance Bitertanol 259-513-5 55179-31-2 1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Bitertanol C20H23N3O2 CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3 InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is identical to the substance Bitertanol 259-513-5 55179-31-2 1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Bitertanol C20H23N3O2 CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3 InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is identical to the substance Bitertanol 259-513-5 55179-31-2 1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Bitertanol C20H23N3O2 CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3 InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is identical to the substance Bitertanol 259-513-5 55179-31-2 1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Bitertanol C20H23N3O2 CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3 InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is identical to the substance Bitertanol 259-513-5 55179-31-2 1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Bitertanol C20H23N3O2 CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3 InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is identical to the substance Bitertanol 259-513-5 55179-31-2 1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Bitertanol C20H23N3O2 CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3 InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is identical to the substance Bitertanol 259-513-5 55179-31-2 1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Bitertanol C20H23N3O2 CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3 InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3 organic compound Other Other gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) (k12)p3478 Not reported yes with Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is identical to the substance Bitertanol 259-513-5 55179-31-2 1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Bitertanol C20H23N3O2 CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3 InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3 organic compound Other Other gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) W3110 Not reported yes without Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is identical to the substance Bitertanol 259-513-5 55179-31-2 1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Bitertanol C20H23N3O2 CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3 InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3 organic compound Other Other gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) (k12)p3478 Not reported yes without Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is identical to the substance Bitertanol 259-513-5 55179-31-2 1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Bitertanol C20H23N3O2 CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3 InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3 organic compound Other Other gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) W3110 Not reported yes with Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bifenthrin 617-373-6 82657-04-3 single chemical entity Component is identical to the substance Bifenthrin 617-373-6 82657-04-3 (2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Bifenthrin C23H22ClF3O2 O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Bifenthrin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin 19May2011 2011 doi:10.2903/j.efsa.2011.2159
+Bifenthrin 617-373-6 82657-04-3 single chemical entity Component is identical to the substance Bifenthrin 617-373-6 82657-04-3 (2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Bifenthrin C23H22ClF3O2 O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Bifenthrin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin 19May2011 2011 doi:10.2903/j.efsa.2011.2159
+Bifenthrin 617-373-6 82657-04-3 single chemical entity Component is identical to the substance Bifenthrin 617-373-6 82657-04-3 (2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Bifenthrin C23H22ClF3O2 O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: France Bifenthrin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin 19May2011 2011 doi:10.2903/j.efsa.2011.2159
+Bifenthrin 617-373-6 82657-04-3 single chemical entity Component is identical to the substance Bifenthrin 617-373-6 82657-04-3 (2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Bifenthrin C23H22ClF3O2 O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Bifenthrin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin 19May2011 2011 doi:10.2903/j.efsa.2011.2159
+Bifenthrin 617-373-6 82657-04-3 single chemical entity Component is identical to the substance Bifenthrin 617-373-6 82657-04-3 (2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Bifenthrin C23H22ClF3O2 O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Bifenthrin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin 19May2011 2011 doi:10.2903/j.efsa.2011.2159
+Bifenthrin 617-373-6 82657-04-3 single chemical entity Component is identical to the substance Bifenthrin 617-373-6 82657-04-3 (2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Bifenthrin C23H22ClF3O2 O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Bifenthrin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin 19May2011 2011 doi:10.2903/j.efsa.2011.2159
+Bifenthrin 617-373-6 82657-04-3 single chemical entity Component is identical to the substance Bifenthrin 617-373-6 82657-04-3 (2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Bifenthrin C23H22ClF3O2 O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: France Bifenthrin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin 19May2011 2011 doi:10.2903/j.efsa.2011.2159
+Bifenthrin 617-373-6 82657-04-3 single chemical entity Component is identical to the substance Bifenthrin 617-373-6 82657-04-3 (2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Bifenthrin C23H22ClF3O2 O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Bifenthrin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin 19May2011 2011 doi:10.2903/j.efsa.2011.2159
+Bifenthrin 617-373-6 82657-04-3 single chemical entity Component is identical to the substance Bifenthrin 617-373-6 82657-04-3 (2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Bifenthrin C23H22ClF3O2 O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Bifenthrin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin 19May2011 2011 doi:10.2903/j.efsa.2011.2159
+Bifenthrin 617-373-6 82657-04-3 single chemical entity Component is identical to the substance Bifenthrin 617-373-6 82657-04-3 (2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Bifenthrin C23H22ClF3O2 O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Bifenthrin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin 19May2011 2011 doi:10.2903/j.efsa.2011.2159
+Bifenthrin 617-373-6 82657-04-3 single chemical entity Component is identical to the substance Bifenthrin 617-373-6 82657-04-3 (2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Bifenthrin C23H22ClF3O2 O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Bifenthrin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin 19May2011 2011 doi:10.2903/j.efsa.2011.2159
+Bifenthrin 617-373-6 82657-04-3 single chemical entity Component is identical to the substance Bifenthrin 617-373-6 82657-04-3 (2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Bifenthrin C23H22ClF3O2 O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Bifenthrin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin 19May2011 2011 doi:10.2903/j.efsa.2011.2159
+Bifenthrin 617-373-6 82657-04-3 single chemical entity Component is identical to the substance Bifenthrin 617-373-6 82657-04-3 (2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Bifenthrin C23H22ClF3O2 O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Bifenthrin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin 19May2011 2011 doi:10.2903/j.efsa.2011.2159
+Bifenthrin 617-373-6 82657-04-3 single chemical entity Component is identical to the substance Bifenthrin 617-373-6 82657-04-3 (2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Bifenthrin C23H22ClF3O2 O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Bifenthrin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin 19May2011 2011 doi:10.2903/j.efsa.2011.2159
+Bifenthrin 617-373-6 82657-04-3 single chemical entity Component is identical to the substance Bifenthrin 617-373-6 82657-04-3 (2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Bifenthrin C23H22ClF3O2 O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Bifenthrin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin 19May2011 2011 doi:10.2903/j.efsa.2011.2159
+Bifenthrin 617-373-6 82657-04-3 single chemical entity Component is identical to the substance Bifenthrin 617-373-6 82657-04-3 (2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Bifenthrin C23H22ClF3O2 O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Bifenthrin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin 19May2011 2011 doi:10.2903/j.efsa.2011.2159
+Bifenthrin 617-373-6 82657-04-3 single chemical entity Component is identical to the substance Bifenthrin 617-373-6 82657-04-3 (2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Bifenthrin C23H22ClF3O2 O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Bifenthrin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin 19May2011 2011 doi:10.2903/j.efsa.2011.2159
+Bifenthrin 617-373-6 82657-04-3 single chemical entity Component is identical to the substance Bifenthrin 617-373-6 82657-04-3 (2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Bifenthrin C23H22ClF3O2 O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Bifenthrin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin 19May2011 2011 doi:10.2903/j.efsa.2011.2159
+Bifenthrin 617-373-6 82657-04-3 single chemical entity Component is identical to the substance Bifenthrin 617-373-6 82657-04-3 (2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Bifenthrin C23H22ClF3O2 O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12- organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: France Bifenthrin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin 19May2011 2011 doi:10.2903/j.efsa.2011.2159
+Bifenthrin 617-373-6 82657-04-3 single chemical entity Component is identical to the substance Bifenthrin 617-373-6 82657-04-3 (2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Bifenthrin C23H22ClF3O2 O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12- organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: France Bifenthrin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin 19May2011 2011 doi:10.2903/j.efsa.2011.2159
+Bifenthrin 617-373-6 82657-04-3 single chemical entity Component is identical to the substance Bifenthrin 617-373-6 82657-04-3 (2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Bifenthrin C23H22ClF3O2 O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12- organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: France Bifenthrin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin 19May2011 2011 doi:10.2903/j.efsa.2011.2159
+Bifenthrin 617-373-6 82657-04-3 single chemical entity Component is identical to the substance Bifenthrin 617-373-6 82657-04-3 (2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Bifenthrin C23H22ClF3O2 O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12- organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: France Bifenthrin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin 19May2011 2011 doi:10.2903/j.efsa.2011.2159
+Bifenthrin 617-373-6 82657-04-3 single chemical entity Component is identical to the substance Bifenthrin 617-373-6 82657-04-3 (2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Bifenthrin C23H22ClF3O2 O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12- organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Inconclusive RMS: France Bifenthrin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin 19May2011 2011 doi:10.2903/j.efsa.2011.2159
+Bifenthrin 617-373-6 82657-04-3 single chemical entity Component is identical to the substance Bifenthrin 617-373-6 82657-04-3 (2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Bifenthrin C23H22ClF3O2 O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12- organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: France Bifenthrin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin 19May2011 2011 doi:10.2903/j.efsa.2011.2159
+Bifenthrin 617-373-6 82657-04-3 single chemical entity Component is identical to the substance Bifenthrin 617-373-6 82657-04-3 (2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Bifenthrin C23H22ClF3O2 O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12- organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: France Bifenthrin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin 19May2011 2011 doi:10.2903/j.efsa.2011.2159
+Bifenthrin 617-373-6 82657-04-3 single chemical entity Component is identical to the substance Bifenthrin 617-373-6 82657-04-3 (2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Bifenthrin C23H22ClF3O2 O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12- organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: France Bifenthrin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin 19May2011 2011 doi:10.2903/j.efsa.2011.2159
+Bifenthrin 617-373-6 82657-04-3 single chemical entity Component is identical to the substance Bifenthrin 617-373-6 82657-04-3 (2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Bifenthrin C23H22ClF3O2 O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12- organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: France Bifenthrin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin 19May2011 2011 doi:10.2903/j.efsa.2011.2159
+Bifenthrin 617-373-6 82657-04-3 single chemical entity Component is identical to the substance Bifenthrin 617-373-6 82657-04-3 (2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Bifenthrin C23H22ClF3O2 O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12- organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: France Bifenthrin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin 19May2011 2011 doi:10.2903/j.efsa.2011.2159
+Bifenthrin 617-373-6 82657-04-3 single chemical entity Component is identical to the substance Bifenthrin 617-373-6 82657-04-3 (2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Bifenthrin C23H22ClF3O2 O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12- organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro According to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: France Bifenthrin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin 19May2011 2011 doi:10.2903/j.efsa.2011.2159
+Bifenthrin 617-373-6 82657-04-3 single chemical entity Component is identical to the substance Bifenthrin 617-373-6 82657-04-3 (2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Bifenthrin C23H22ClF3O2 O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12- organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro According to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: France Bifenthrin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin 19May2011 2011 doi:10.2903/j.efsa.2011.2159
+Bifenthrin 617-373-6 82657-04-3 single chemical entity Component is identical to the substance Bifenthrin 617-373-6 82657-04-3 (2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Bifenthrin C23H22ClF3O2 O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12- organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes without Negative RMS: France Bifenthrin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin 19May2011 2011 doi:10.2903/j.efsa.2011.2159
+Bifenthrin 617-373-6 82657-04-3 single chemical entity Component is identical to the substance Bifenthrin 617-373-6 82657-04-3 (2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Bifenthrin C23H22ClF3O2 O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12- organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes with Negative RMS: France Bifenthrin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin 19May2011 2011 doi:10.2903/j.efsa.2011.2159
+Bifenthrin 617-373-6 82657-04-3 single chemical entity Component is identical to the substance Bifenthrin 617-373-6 82657-04-3 (2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Bifenthrin C23H22ClF3O2 O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12- organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) ICR 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: France Bifenthrin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin 19May2011 2011 doi:10.2903/j.efsa.2011.2159
+Bifenthrin 617-373-6 82657-04-3 single chemical entity Component is identical to the substance Bifenthrin 617-373-6 82657-04-3 (2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Bifenthrin C23H22ClF3O2 O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12- organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) ICR 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: France Bifenthrin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin 19May2011 2011 doi:10.2903/j.efsa.2011.2159
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Positive RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Positive RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Positive RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Positive RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Positive RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Positive RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Positive RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Positive RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Positive RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Positive RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Positive RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Positive RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Positive RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Positive RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Positive RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Positive RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Positive RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Positive RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Positive RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Positive RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Positive RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Positive RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No data Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data no data Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-ol 216-350-4 1563-38-8 2,2-dimethyl-3H-1-benzofuran-7-ol Not in list C10H12O2 CC1(CC2=C(O1)C(=CC=C2)O)C InChI=1S/C10H12O2/c1-10(2)6-7-4-3-5-8(11)9(7)12-10/h3-5,11H,6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data without Positive no information RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-ol 216-350-4 1563-38-8 2,2-dimethyl-3H-1-benzofuran-7-ol Not in list C10H12O2 CC1(CC2=C(O1)C(=CC=C2)O)C InChI=1S/C10H12O2/c1-10(2)6-7-4-3-5-8(11)9(7)12-10/h3-5,11H,6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data with Positive no information RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data with Negative no information RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data without Positive no information RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No data Acceptable Hamster (as animal) CHO Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No data Acceptable Hamster (as animal) CHO Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No data Acceptable Hamster (as animal) CHO Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No data Acceptable Hamster (as animal) CHO Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No data Acceptable Human (as organism) HeLa cells Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No data Acceptable Rat (as animal) hepatocytes Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No data Acceptable Human (as organism) fibroblast Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable House mouse (as animal) Not reported No data oral: gavage no data not applicable Negative no evidence RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No data Acceptable House mouse (as animal) Not reported No data oral: unspecified no data not applicable Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No data Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data with Positive no information RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No data Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data without Positive no information RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-ol 216-350-4 1563-38-8 2,2-dimethyl-3H-1-benzofuran-7-ol Not in list C10H12O2 CC1(CC2=C(O1)C(=CC=C2)O)C InChI=1S/C10H12O2/c1-10(2)6-7-4-3-5-8(11)9(7)12-10/h3-5,11H,6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Positive large colonies RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-ol 216-350-4 1563-38-8 2,2-dimethyl-3H-1-benzofuran-7-ol Not in list C10H12O2 CC1(CC2=C(O1)C(=CC=C2)O)C InChI=1S/C10H12O2/c1-10(2)6-7-4-3-5-8(11)9(7)12-10/h3-5,11H,6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Positive small colonies RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-ol 216-350-4 1563-38-8 2,2-dimethyl-3H-1-benzofuran-7-ol Not in list C10H12O2 CC1(CC2=C(O1)C(=CC=C2)O)C InChI=1S/C10H12O2/c1-10(2)6-7-4-3-5-8(11)9(7)12-10/h3-5,11H,6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Positive large colonies RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-ol 216-350-4 1563-38-8 2,2-dimethyl-3H-1-benzofuran-7-ol Not in list C10H12O2 CC1(CC2=C(O1)C(=CC=C2)O)C InChI=1S/C10H12O2/c1-10(2)6-7-4-3-5-8(11)9(7)12-10/h3-5,11H,6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Positive small colonies RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-ol 216-350-4 1563-38-8 2,2-dimethyl-3H-1-benzofuran-7-ol Not in list C10H12O2 CC1(CC2=C(O1)C(=CC=C2)O)C InChI=1S/C10H12O2/c1-10(2)6-7-4-3-5-8(11)9(7)12-10/h3-5,11H,6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-ol 216-350-4 1563-38-8 2,2-dimethyl-3H-1-benzofuran-7-ol Not in list C10H12O2 CC1(CC2=C(O1)C(=CC=C2)O)C InChI=1S/C10H12O2/c1-10(2)6-7-4-3-5-8(11)9(7)12-10/h3-5,11H,6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-ol 216-350-4 1563-38-8 2,2-dimethyl-3H-1-benzofuran-7-ol Not in list C10H12O2 CC1(CC2=C(O1)C(=CC=C2)O)C InChI=1S/C10H12O2/c1-10(2)6-7-4-3-5-8(11)9(7)12-10/h3-5,11H,6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-ol 216-350-4 1563-38-8 2,2-dimethyl-3H-1-benzofuran-7-ol Not in list C10H12O2 CC1(CC2=C(O1)C(=CC=C2)O)C InChI=1S/C10H12O2/c1-10(2)6-7-4-3-5-8(11)9(7)12-10/h3-5,11H,6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-ol 216-350-4 1563-38-8 2,2-dimethyl-3H-1-benzofuran-7-ol Not in list C10H12O2 CC1(CC2=C(O1)C(=CC=C2)O)C InChI=1S/C10H12O2/c1-10(2)6-7-4-3-5-8(11)9(7)12-10/h3-5,11H,6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-ol 216-350-4 1563-38-8 2,2-dimethyl-3H-1-benzofuran-7-ol Not in list C10H12O2 CC1(CC2=C(O1)C(=CC=C2)O)C InChI=1S/C10H12O2/c1-10(2)6-7-4-3-5-8(11)9(7)12-10/h3-5,11H,6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-ol 216-350-4 1563-38-8 2,2-dimethyl-3H-1-benzofuran-7-ol Not in list C10H12O2 CC1(CC2=C(O1)C(=CC=C2)O)C InChI=1S/C10H12O2/c1-10(2)6-7-4-3-5-8(11)9(7)12-10/h3-5,11H,6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-ol 216-350-4 1563-38-8 2,2-dimethyl-3H-1-benzofuran-7-ol Not in list C10H12O2 CC1(CC2=C(O1)C(=CC=C2)O)C InChI=1S/C10H12O2/c1-10(2)6-7-4-3-5-8(11)9(7)12-10/h3-5,11H,6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-ol 216-350-4 1563-38-8 2,2-dimethyl-3H-1-benzofuran-7-ol Not in list C10H12O2 CC1(CC2=C(O1)C(=CC=C2)O)C InChI=1S/C10H12O2/c1-10(2)6-7-4-3-5-8(11)9(7)12-10/h3-5,11H,6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-ol 216-350-4 1563-38-8 2,2-dimethyl-3H-1-benzofuran-7-ol Not in list C10H12O2 CC1(CC2=C(O1)C(=CC=C2)O)C InChI=1S/C10H12O2/c1-10(2)6-7-4-3-5-8(11)9(7)12-10/h3-5,11H,6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is a metabolite of the substance 3-hydroxy-2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate 16655-82-6 (3-hydroxy-2,2-dimethyl-3H-1-benzofuran-7-yl) N-methylcarbamate Not in list C12H15NO4 CC1(C(C2=C(O1)C(=CC=C2)OC(=O)NC)O)C InChI=1S/C12H15NO4/c1-12(2)10(14)7-5-4-6-8(9(7)17-12)16-11(15)13-3/h4-6,10,14H,1-3H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Positive large colonies RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported no data with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Positive large colonies RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is a metabolite of the substance 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-ol 216-350-4 1563-38-8 2,2-dimethyl-3H-1-benzofuran-7-ol Not in list C10H12O2 CC1(CC2=C(O1)C(=CC=C2)O)C InChI=1S/C10H12O2/c1-10(2)6-7-4-3-5-8(11)9(7)12-10/h3-5,11H,6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Positive small colonies RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported no data without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Positive small colonies RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Positive large colonies RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is a metabolite of the substance 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-ol 216-350-4 1563-38-8 2,2-dimethyl-3H-1-benzofuran-7-ol Not in list C10H12O2 CC1(CC2=C(O1)C(=CC=C2)O)C InChI=1S/C10H12O2/c1-10(2)6-7-4-3-5-8(11)9(7)12-10/h3-5,11H,6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is a metabolite of the substance 3-hydroxy-2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate 16655-82-6 (3-hydroxy-2,2-dimethyl-3H-1-benzofuran-7-yl) N-methylcarbamate Not in list C12H15NO4 CC1(C(C2=C(O1)C(=CC=C2)OC(=O)NC)O)C InChI=1S/C12H15NO4/c1-12(2)10(14)7-5-4-6-8(9(7)17-12)16-11(15)13-3/h4-6,10,14H,1-3H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Positive large colonies RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is a metabolite of the substance 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-ol 216-350-4 1563-38-8 2,2-dimethyl-3H-1-benzofuran-7-ol Not in list C10H12O2 CC1(CC2=C(O1)C(=CC=C2)O)C InChI=1S/C10H12O2/c1-10(2)6-7-4-3-5-8(11)9(7)12-10/h3-5,11H,6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is a metabolite of the substance 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-ol 216-350-4 1563-38-8 2,2-dimethyl-3H-1-benzofuran-7-ol Not in list C10H12O2 CC1(CC2=C(O1)C(=CC=C2)O)C InChI=1S/C10H12O2/c1-10(2)6-7-4-3-5-8(11)9(7)12-10/h3-5,11H,6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported no data without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is a metabolite of the substance 3-hydroxy-2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate 16655-82-6 (3-hydroxy-2,2-dimethyl-3H-1-benzofuran-7-yl) N-methylcarbamate Not in list C12H15NO4 CC1(C(C2=C(O1)C(=CC=C2)OC(=O)NC)O)C InChI=1S/C12H15NO4/c1-12(2)10(14)7-5-4-6-8(9(7)17-12)16-11(15)13-3/h4-6,10,14H,1-3H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Positive small colonies RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is a metabolite of the substance 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-ol 216-350-4 1563-38-8 2,2-dimethyl-3H-1-benzofuran-7-ol Not in list C10H12O2 CC1(CC2=C(O1)C(=CC=C2)O)C InChI=1S/C10H12O2/c1-10(2)6-7-4-3-5-8(11)9(7)12-10/h3-5,11H,6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is a metabolite of the substance 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-ol 216-350-4 1563-38-8 2,2-dimethyl-3H-1-benzofuran-7-ol Not in list C10H12O2 CC1(CC2=C(O1)C(=CC=C2)O)C InChI=1S/C10H12O2/c1-10(2)6-7-4-3-5-8(11)9(7)12-10/h3-5,11H,6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is a metabolite of the substance 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-ol 216-350-4 1563-38-8 2,2-dimethyl-3H-1-benzofuran-7-ol Not in list C10H12O2 CC1(CC2=C(O1)C(=CC=C2)O)C InChI=1S/C10H12O2/c1-10(2)6-7-4-3-5-8(11)9(7)12-10/h3-5,11H,6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is a metabolite of the substance 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-ol 216-350-4 1563-38-8 2,2-dimethyl-3H-1-benzofuran-7-ol Not in list C10H12O2 CC1(CC2=C(O1)C(=CC=C2)O)C InChI=1S/C10H12O2/c1-10(2)6-7-4-3-5-8(11)9(7)12-10/h3-5,11H,6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is a metabolite of the substance 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-ol 216-350-4 1563-38-8 2,2-dimethyl-3H-1-benzofuran-7-ol Not in list C10H12O2 CC1(CC2=C(O1)C(=CC=C2)O)C InChI=1S/C10H12O2/c1-10(2)6-7-4-3-5-8(11)9(7)12-10/h3-5,11H,6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported no data with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is a metabolite of the substance 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-ol 216-350-4 1563-38-8 2,2-dimethyl-3H-1-benzofuran-7-ol Not in list C10H12O2 CC1(CC2=C(O1)C(=CC=C2)O)C InChI=1S/C10H12O2/c1-10(2)6-7-4-3-5-8(11)9(7)12-10/h3-5,11H,6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is a metabolite of the substance 3-hydroxy-2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate 16655-82-6 (3-hydroxy-2,2-dimethyl-3H-1-benzofuran-7-yl) N-methylcarbamate Not in list C12H15NO4 CC1(C(C2=C(O1)C(=CC=C2)OC(=O)NC)O)C InChI=1S/C12H15NO4/c1-12(2)10(14)7-5-4-6-8(9(7)17-12)16-11(15)13-3/h4-6,10,14H,1-3H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Positive small colonies RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is a metabolite of the substance 3-hydroxy-2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate 16655-82-6 (3-hydroxy-2,2-dimethyl-3H-1-benzofuran-7-yl) N-methylcarbamate Not in list C12H15NO4 CC1(C(C2=C(O1)C(=CC=C2)OC(=O)NC)O)C InChI=1S/C12H15NO4/c1-12(2)10(14)7-5-4-6-8(9(7)17-12)16-11(15)13-3/h4-6,10,14H,1-3H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is a metabolite of the substance 3-hydroxy-2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate 16655-82-6 (3-hydroxy-2,2-dimethyl-3H-1-benzofuran-7-yl) N-methylcarbamate Not in list C12H15NO4 CC1(C(C2=C(O1)C(=CC=C2)OC(=O)NC)O)C InChI=1S/C12H15NO4/c1-12(2)10(14)7-5-4-6-8(9(7)17-12)16-11(15)13-3/h4-6,10,14H,1-3H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is a metabolite of the substance 3-hydroxy-2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate 16655-82-6 (3-hydroxy-2,2-dimethyl-3H-1-benzofuran-7-yl) N-methylcarbamate Not in list C12H15NO4 CC1(C(C2=C(O1)C(=CC=C2)OC(=O)NC)O)C InChI=1S/C12H15NO4/c1-12(2)10(14)7-5-4-6-8(9(7)17-12)16-11(15)13-3/h4-6,10,14H,1-3H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is a metabolite of the substance 3-hydroxy-2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate 16655-82-6 (3-hydroxy-2,2-dimethyl-3H-1-benzofuran-7-yl) N-methylcarbamate Not in list C12H15NO4 CC1(C(C2=C(O1)C(=CC=C2)OC(=O)NC)O)C InChI=1S/C12H15NO4/c1-12(2)10(14)7-5-4-6-8(9(7)17-12)16-11(15)13-3/h4-6,10,14H,1-3H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is a metabolite of the substance 3-hydroxy-2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate 16655-82-6 (3-hydroxy-2,2-dimethyl-3H-1-benzofuran-7-yl) N-methylcarbamate Not in list C12H15NO4 CC1(C(C2=C(O1)C(=CC=C2)OC(=O)NC)O)C InChI=1S/C12H15NO4/c1-12(2)10(14)7-5-4-6-8(9(7)17-12)16-11(15)13-3/h4-6,10,14H,1-3H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is a metabolite of the substance 3-hydroxy-2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate 16655-82-6 (3-hydroxy-2,2-dimethyl-3H-1-benzofuran-7-yl) N-methylcarbamate Not in list C12H15NO4 CC1(C(C2=C(O1)C(=CC=C2)OC(=O)NC)O)C InChI=1S/C12H15NO4/c1-12(2)10(14)7-5-4-6-8(9(7)17-12)16-11(15)13-3/h4-6,10,14H,1-3H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Positive RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is a metabolite of the substance 3-hydroxy-2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate 16655-82-6 (3-hydroxy-2,2-dimethyl-3H-1-benzofuran-7-yl) N-methylcarbamate Not in list C12H15NO4 CC1(C(C2=C(O1)C(=CC=C2)OC(=O)NC)O)C InChI=1S/C12H15NO4/c1-12(2)10(14)7-5-4-6-8(9(7)17-12)16-11(15)13-3/h4-6,10,14H,1-3H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is a metabolite of the substance 3-hydroxy-2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate 16655-82-6 (3-hydroxy-2,2-dimethyl-3H-1-benzofuran-7-yl) N-methylcarbamate Not in list C12H15NO4 CC1(C(C2=C(O1)C(=CC=C2)OC(=O)NC)O)C InChI=1S/C12H15NO4/c1-12(2)10(14)7-5-4-6-8(9(7)17-12)16-11(15)13-3/h4-6,10,14H,1-3H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is a metabolite of the substance 3-hydroxy-2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate 16655-82-6 (3-hydroxy-2,2-dimethyl-3H-1-benzofuran-7-yl) N-methylcarbamate Not in list C12H15NO4 CC1(C(C2=C(O1)C(=CC=C2)OC(=O)NC)O)C InChI=1S/C12H15NO4/c1-12(2)10(14)7-5-4-6-8(9(7)17-12)16-11(15)13-3/h4-6,10,14H,1-3H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported no data with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported no data without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Positive RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported no data with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is a metabolite of the substance 3-hydroxy-2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate 16655-82-6 (3-hydroxy-2,2-dimethyl-3H-1-benzofuran-7-yl) N-methylcarbamate Not in list C12H15NO4 CC1(C(C2=C(O1)C(=CC=C2)OC(=O)NC)O)C InChI=1S/C12H15NO4/c1-12(2)10(14)7-5-4-6-8(9(7)17-12)16-11(15)13-3/h4-6,10,14H,1-3H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported no data without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance 3-hydroxy-2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate 16655-82-6 (3-hydroxy-2,2-dimethyl-3H-1-benzofuran-7-yl) N-methylcarbamate Not in list C12H15NO4 CC1(C(C2=C(O1)C(=CC=C2)OC(=O)NC)O)C InChI=1S/C12H15NO4/c1-12(2)10(14)7-5-4-6-8(9(7)17-12)16-11(15)13-3/h4-6,10,14H,1-3H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance 3-hydroxy-2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate 16655-82-6 (3-hydroxy-2,2-dimethyl-3H-1-benzofuran-7-yl) N-methylcarbamate Not in list C12H15NO4 CC1(C(C2=C(O1)C(=CC=C2)OC(=O)NC)O)C InChI=1S/C12H15NO4/c1-12(2)10(14)7-5-4-6-8(9(7)17-12)16-11(15)13-3/h4-6,10,14H,1-3H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance 3-hydroxy-2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate 16655-82-6 (3-hydroxy-2,2-dimethyl-3H-1-benzofuran-7-yl) N-methylcarbamate Not in list C12H15NO4 CC1(C(C2=C(O1)C(=CC=C2)OC(=O)NC)O)C InChI=1S/C12H15NO4/c1-12(2)10(14)7-5-4-6-8(9(7)17-12)16-11(15)13-3/h4-6,10,14H,1-3H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance 3-hydroxy-2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate 16655-82-6 (3-hydroxy-2,2-dimethyl-3H-1-benzofuran-7-yl) N-methylcarbamate Not in list C12H15NO4 CC1(C(C2=C(O1)C(=CC=C2)OC(=O)NC)O)C InChI=1S/C12H15NO4/c1-12(2)10(14)7-5-4-6-8(9(7)17-12)16-11(15)13-3/h4-6,10,14H,1-3H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance 3-hydroxy-2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate 16655-82-6 (3-hydroxy-2,2-dimethyl-3H-1-benzofuran-7-yl) N-methylcarbamate Not in list C12H15NO4 CC1(C(C2=C(O1)C(=CC=C2)OC(=O)NC)O)C InChI=1S/C12H15NO4/c1-12(2)10(14)7-5-4-6-8(9(7)17-12)16-11(15)13-3/h4-6,10,14H,1-3H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Positive RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance 3-hydroxy-2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate 16655-82-6 (3-hydroxy-2,2-dimethyl-3H-1-benzofuran-7-yl) N-methylcarbamate Not in list C12H15NO4 CC1(C(C2=C(O1)C(=CC=C2)OC(=O)NC)O)C InChI=1S/C12H15NO4/c1-12(2)10(14)7-5-4-6-8(9(7)17-12)16-11(15)13-3/h4-6,10,14H,1-3H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance 3-hydroxy-2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate 16655-82-6 (3-hydroxy-2,2-dimethyl-3H-1-benzofuran-7-yl) N-methylcarbamate Not in list C12H15NO4 CC1(C(C2=C(O1)C(=CC=C2)OC(=O)NC)O)C InChI=1S/C12H15NO4/c1-12(2)10(14)7-5-4-6-8(9(7)17-12)16-11(15)13-3/h4-6,10,14H,1-3H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance 3-hydroxy-2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate 16655-82-6 (3-hydroxy-2,2-dimethyl-3H-1-benzofuran-7-yl) N-methylcarbamate Not in list C12H15NO4 CC1(C(C2=C(O1)C(=CC=C2)OC(=O)NC)O)C InChI=1S/C12H15NO4/c1-12(2)10(14)7-5-4-6-8(9(7)17-12)16-11(15)13-3/h4-6,10,14H,1-3H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance 3-hydroxy-2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate 16655-82-6 (3-hydroxy-2,2-dimethyl-3H-1-benzofuran-7-yl) N-methylcarbamate Not in list C12H15NO4 CC1(C(C2=C(O1)C(=CC=C2)OC(=O)NC)O)C InChI=1S/C12H15NO4/c1-12(2)10(14)7-5-4-6-8(9(7)17-12)16-11(15)13-3/h4-6,10,14H,1-3H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance 3-hydroxy-2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate 16655-82-6 (3-hydroxy-2,2-dimethyl-3H-1-benzofuran-7-yl) N-methylcarbamate Not in list C12H15NO4 CC1(C(C2=C(O1)C(=CC=C2)OC(=O)NC)O)C InChI=1S/C12H15NO4/c1-12(2)10(14)7-5-4-6-8(9(7)17-12)16-11(15)13-3/h4-6,10,14H,1-3H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Diphenylamine 204-539-4 122-39-4 single chemical entity Component is identical to the substance Diphenylamine 204-539-4 122-39-4 N-phenylaniline Diphenylamine C12H11N N(c1ccccc1)c2ccccc2 InChI=1/C12H11N/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h1-10,13H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Ireland Diphenylamine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diphenylamine 25Jan2012 2012 doi:10.2903/j.efsa.2012.2486
+Diphenylamine 204-539-4 122-39-4 single chemical entity Component is identical to the substance Diphenylamine 204-539-4 122-39-4 N-phenylaniline Diphenylamine C12H11N N(c1ccccc1)c2ccccc2 InChI=1/C12H11N/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h1-10,13H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Ireland Diphenylamine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diphenylamine 25Jan2012 2012 doi:10.2903/j.efsa.2012.2486
+Diphenylamine 204-539-4 122-39-4 single chemical entity Component is identical to the substance Diphenylamine 204-539-4 122-39-4 N-phenylaniline Diphenylamine C12H11N N(c1ccccc1)c2ccccc2 InChI=1/C12H11N/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h1-10,13H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Ireland Diphenylamine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diphenylamine 25Jan2012 2012 doi:10.2903/j.efsa.2012.2486
+Diphenylamine 204-539-4 122-39-4 single chemical entity Component is identical to the substance Diphenylamine 204-539-4 122-39-4 N-phenylaniline Diphenylamine C12H11N N(c1ccccc1)c2ccccc2 InChI=1/C12H11N/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h1-10,13H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Ireland Diphenylamine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diphenylamine 25Jan2012 2012 doi:10.2903/j.efsa.2012.2486
+Diphenylamine 204-539-4 122-39-4 single chemical entity Component is identical to the substance Diphenylamine 204-539-4 122-39-4 N-phenylaniline Diphenylamine C12H11N N(c1ccccc1)c2ccccc2 InChI=1/C12H11N/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h1-10,13H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Ireland Diphenylamine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diphenylamine 25Jan2012 2012 doi:10.2903/j.efsa.2012.2486
+Diphenylamine 204-539-4 122-39-4 single chemical entity Component is identical to the substance Diphenylamine 204-539-4 122-39-4 N-phenylaniline Diphenylamine C12H11N N(c1ccccc1)c2ccccc2 InChI=1/C12H11N/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h1-10,13H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Ireland Diphenylamine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diphenylamine 25Jan2012 2012 doi:10.2903/j.efsa.2012.2486
+Diphenylamine 204-539-4 122-39-4 single chemical entity Component is identical to the substance Diphenylamine 204-539-4 122-39-4 N-phenylaniline Diphenylamine C12H11N N(c1ccccc1)c2ccccc2 InChI=1/C12H11N/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h1-10,13H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Ireland Diphenylamine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diphenylamine 25Jan2012 2012 doi:10.2903/j.efsa.2012.2486
+Diphenylamine 204-539-4 122-39-4 single chemical entity Component is identical to the substance Diphenylamine 204-539-4 122-39-4 N-phenylaniline Diphenylamine C12H11N N(c1ccccc1)c2ccccc2 InChI=1/C12H11N/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h1-10,13H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Ireland Diphenylamine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diphenylamine 25Jan2012 2012 doi:10.2903/j.efsa.2012.2486
+Diphenylamine 204-539-4 122-39-4 single chemical entity Component is identical to the substance Diphenylamine 204-539-4 122-39-4 N-phenylaniline Diphenylamine C12H11N N(c1ccccc1)c2ccccc2 InChI=1/C12H11N/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h1-10,13H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Ireland Diphenylamine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diphenylamine 25Jan2012 2012 doi:10.2903/j.efsa.2012.2486
+Diphenylamine 204-539-4 122-39-4 single chemical entity Component is identical to the substance Diphenylamine 204-539-4 122-39-4 N-phenylaniline Diphenylamine C12H11N N(c1ccccc1)c2ccccc2 InChI=1/C12H11N/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h1-10,13H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Ireland Diphenylamine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diphenylamine 25Jan2012 2012 doi:10.2903/j.efsa.2012.2486
+Diphenylamine 204-539-4 122-39-4 single chemical entity Component is identical to the substance Diphenylamine 204-539-4 122-39-4 N-phenylaniline Diphenylamine C12H11N N(c1ccccc1)c2ccccc2 InChI=1/C12H11N/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h1-10,13H organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Ireland Diphenylamine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diphenylamine 25Jan2012 2012 doi:10.2903/j.efsa.2012.2486
+Diphenylamine 204-539-4 122-39-4 single chemical entity Component is identical to the substance Diphenylamine 204-539-4 122-39-4 N-phenylaniline Diphenylamine C12H11N N(c1ccccc1)c2ccccc2 InChI=1/C12H11N/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h1-10,13H organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Positive no information RMS: Ireland Diphenylamine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diphenylamine 25Jan2012 2012 doi:10.2903/j.efsa.2012.2486
+Diphenylamine 204-539-4 122-39-4 single chemical entity Component is identical to the substance Diphenylamine 204-539-4 122-39-4 N-phenylaniline Diphenylamine C12H11N N(c1ccccc1)c2ccccc2 InChI=1/C12H11N/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h1-10,13H organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Positive RMS: Ireland Diphenylamine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diphenylamine 25Jan2012 2012 doi:10.2903/j.efsa.2012.2486
+Diphenylamine 204-539-4 122-39-4 single chemical entity Component is identical to the substance Diphenylamine 204-539-4 122-39-4 N-phenylaniline Diphenylamine C12H11N N(c1ccccc1)c2ccccc2 InChI=1/C12H11N/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h1-10,13H organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Ireland Diphenylamine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diphenylamine 25Jan2012 2012 doi:10.2903/j.efsa.2012.2486
+Diphenylamine 204-539-4 122-39-4 single chemical entity Component is identical to the substance Diphenylamine 204-539-4 122-39-4 N-phenylaniline Diphenylamine C12H11N N(c1ccccc1)c2ccccc2 InChI=1/C12H11N/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h1-10,13H organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) ICR 10 Male/Female oral: unspecified 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Ireland Diphenylamine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diphenylamine 25Jan2012 2012 doi:10.2903/j.efsa.2012.2486
+Diphenylamine 204-539-4 122-39-4 single chemical entity Component is identical to the substance Diphenylamine 204-539-4 122-39-4 N-phenylaniline Diphenylamine C12H11N N(c1ccccc1)c2ccccc2 InChI=1/C12H11N/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h1-10,13H organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) ICR 10 Male/Female oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Ireland Diphenylamine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diphenylamine 25Jan2012 2012 doi:10.2903/j.efsa.2012.2486
+Diphenylamine 204-539-4 122-39-4 single chemical entity Component is identical to the substance Diphenylamine 204-539-4 122-39-4 N-phenylaniline Diphenylamine C12H11N N(c1ccccc1)c2ccccc2 InChI=1/C12H11N/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h1-10,13H organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) ICR 10 Male/Female oral: unspecified 72.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Ireland Diphenylamine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diphenylamine 25Jan2012 2012 doi:10.2903/j.efsa.2012.2486
+Diphenylamine 204-539-4 122-39-4 single chemical entity Component is identical to the substance Diphenylamine 204-539-4 122-39-4 N-phenylaniline Diphenylamine C12H11N N(c1ccccc1)c2ccccc2 InChI=1/C12H11N/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h1-10,13H organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Fischer344 4 Male oral: unspecified 16.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Ireland Diphenylamine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diphenylamine 25Jan2012 2012 doi:10.2903/j.efsa.2012.2486
+Diphenylamine 204-539-4 122-39-4 single chemical entity Component is identical to the substance Diphenylamine 204-539-4 122-39-4 N-phenylaniline Diphenylamine C12H11N N(c1ccccc1)c2ccccc2 InChI=1/C12H11N/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h1-10,13H organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Fischer344 4 Male oral: unspecified 4.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Ireland Diphenylamine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diphenylamine 25Jan2012 2012 doi:10.2903/j.efsa.2012.2486
+Emamectin 605-015-1 119791-41-2 single chemical entity Component is part of a group assessment Emamectin Hydrochloride Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The Netherlands Emamectin 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance emamectin 21Nov2012 2012 doi:10.2903/j.efsa.2012.2955
+Emamectin 605-015-1 119791-41-2 single chemical entity Component is part of a group assessment Emamectin Hydrochloride Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: The Netherlands Emamectin 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance emamectin 21Nov2012 2012 doi:10.2903/j.efsa.2012.2955
+Emamectin 605-015-1 119791-41-2 single chemical entity Component is part of a group assessment Emamectin Hydrochloride Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The Netherlands Emamectin 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance emamectin 21Nov2012 2012 doi:10.2903/j.efsa.2012.2955
+Emamectin 605-015-1 119791-41-2 single chemical entity Component is part of a group assessment Emamectin Hydrochloride Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The Netherlands Emamectin 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance emamectin 21Nov2012 2012 doi:10.2903/j.efsa.2012.2955
+Emamectin 605-015-1 119791-41-2 single chemical entity Component is part of a group assessment Emamectin Hydrochloride Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes without Negative RMS: The Netherlands Emamectin 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance emamectin 21Nov2012 2012 doi:10.2903/j.efsa.2012.2955
+Emamectin 605-015-1 119791-41-2 single chemical entity Component is part of a group assessment Emamectin Hydrochloride Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The Netherlands Emamectin 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance emamectin 21Nov2012 2012 doi:10.2903/j.efsa.2012.2955
+Emamectin 605-015-1 119791-41-2 single chemical entity Component is part of a group assessment Emamectin Hydrochloride Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes with Negative RMS: The Netherlands Emamectin 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance emamectin 21Nov2012 2012 doi:10.2903/j.efsa.2012.2955
+Emamectin 605-015-1 119791-41-2 single chemical entity Component is part of a group assessment Emamectin Hydrochloride Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The Netherlands Emamectin 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance emamectin 21Nov2012 2012 doi:10.2903/j.efsa.2012.2955
+Emamectin 605-015-1 119791-41-2 single chemical entity Component is part of a group assessment Emamectin Hydrochloride Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The Netherlands Emamectin 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance emamectin 21Nov2012 2012 doi:10.2903/j.efsa.2012.2955
+Emamectin 605-015-1 119791-41-2 single chemical entity Component is part of a group assessment Emamectin Hydrochloride Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes without Negative RMS: The Netherlands Emamectin 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance emamectin 21Nov2012 2012 doi:10.2903/j.efsa.2012.2955
+Emamectin 605-015-1 119791-41-2 single chemical entity Component is part of a group assessment Emamectin Hydrochloride Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes without Negative RMS: The Netherlands Emamectin 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance emamectin 21Nov2012 2012 doi:10.2903/j.efsa.2012.2955
+Emamectin 605-015-1 119791-41-2 single chemical entity Component is part of a group assessment Emamectin Hydrochloride Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes with Negative RMS: The Netherlands Emamectin 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance emamectin 21Nov2012 2012 doi:10.2903/j.efsa.2012.2955
+Emamectin 605-015-1 119791-41-2 single chemical entity Component is part of a group assessment Emamectin Hydrochloride Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: The Netherlands Emamectin 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance emamectin 21Nov2012 2012 doi:10.2903/j.efsa.2012.2955
+Emamectin 605-015-1 119791-41-2 single chemical entity Component is part of a group assessment Emamectin Hydrochloride Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes with Negative RMS: The Netherlands Emamectin 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance emamectin 21Nov2012 2012 doi:10.2903/j.efsa.2012.2955
+Emamectin 605-015-1 119791-41-2 single chemical entity Component is part of a group assessment Emamectin Hydrochloride Not in list organic no structure gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Negative RMS: The Netherlands Emamectin 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance emamectin 21Nov2012 2012 doi:10.2903/j.efsa.2012.2955
+Emamectin 605-015-1 119791-41-2 single chemical entity Component is part of a group assessment Emamectin Hydrochloride Not in list organic no structure gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: The Netherlands Emamectin 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance emamectin 21Nov2012 2012 doi:10.2903/j.efsa.2012.2955
+Emamectin 605-015-1 119791-41-2 single chemical entity Component is part of a group assessment Emamectin benzoate 155569-91-8 - Not in list C56H81NO15 CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)[NH2+]C)OC)OC)C)C.C1=CC=C(C=C1)C(=O)[O-] InChI=1S/C49H75NO13.C7H6O2/c1-12-26(2)44-29(5)18-19-48(63-44)24-35-21-34(62-48)17-16-28(4)43(27(3)14-13-15-33-25-56-46-42(51)30(6)20-36(47(52)59-35)49(33,46)53)60-40-23-38(55-11)45(32(8)58-40)61-39-22-37(54-10)41(50-9)31(7)57-39;8-7(9)6-4-2-1-3-5-6/h13-16,18-20,26-27,29,31-32,34-46,50-51,53H,12,17,21-25H2,1-11H3;1-5H,(H,8,9)/b14-13+,28-16+,33-15+;/t26-,27-,29-,31-,32-,34+,35-,36-,37-,38-,39-,40-,41-,42+,43-,44+,45-,46+,48+,49+;/m0./s1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: The Netherlands Emamectin 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance emamectin 21Nov2012 2012 doi:10.2903/j.efsa.2012.2955
+Emamectin 605-015-1 119791-41-2 single chemical entity Component is part of a group assessment Emamectin benzoate 155569-91-8 - Not in list C56H81NO15 CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)[NH2+]C)OC)OC)C)C.C1=CC=C(C=C1)C(=O)[O-] InChI=1S/C49H75NO13.C7H6O2/c1-12-26(2)44-29(5)18-19-48(63-44)24-35-21-34(62-48)17-16-28(4)43(27(3)14-13-15-33-25-56-46-42(51)30(6)20-36(47(52)59-35)49(33,46)53)60-40-23-38(55-11)45(32(8)58-40)61-39-22-37(54-10)41(50-9)31(7)57-39;8-7(9)6-4-2-1-3-5-6/h13-16,18-20,26-27,29,31-32,34-46,50-51,53H,12,17,21-25H2,1-11H3;1-5H,(H,8,9)/b14-13+,28-16+,33-15+;/t26-,27-,29-,31-,32-,34+,35-,36-,37-,38-,39-,40-,41-,42+,43-,44+,45-,46+,48+,49+;/m0./s1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: The Netherlands Emamectin 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance emamectin 21Nov2012 2012 doi:10.2903/j.efsa.2012.2955
+Emamectin 605-015-1 119791-41-2 single chemical entity Component is part of a group assessment Emamectin Hydrochloride Not in list organic no structure DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vitro No guideline available Not reported Not applicable Acceptable Rat (as animal) hepatocytes Not reported no data without Negative RMS: The Netherlands Emamectin 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance emamectin 21Nov2012 2012 doi:10.2903/j.efsa.2012.2955
+Emamectin 605-015-1 119791-41-2 single chemical entity Component is part of a group assessment Emamectin benzoate 155569-91-8 - Not in list C56H81NO15 CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)[NH2+]C)OC)OC)C)C.C1=CC=C(C=C1)C(=O)[O-] InChI=1S/C49H75NO13.C7H6O2/c1-12-26(2)44-29(5)18-19-48(63-44)24-35-21-34(62-48)17-16-28(4)43(27(3)14-13-15-33-25-56-46-42(51)30(6)20-36(47(52)59-35)49(33,46)53)60-40-23-38(55-11)45(32(8)58-40)61-39-22-37(54-10)41(50-9)31(7)57-39;8-7(9)6-4-2-1-3-5-6/h13-16,18-20,26-27,29,31-32,34-46,50-51,53H,12,17,21-25H2,1-11H3;1-5H,(H,8,9)/b14-13+,28-16+,33-15+;/t26-,27-,29-,31-,32-,34+,35-,36-,37-,38-,39-,40-,41-,42+,43-,44+,45-,46+,48+,49+;/m0./s1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable House mouse (as animal) CD-1 10 Male oral: gavage 48.0000000000 h yes not applicable Negative RMS: The Netherlands Emamectin 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance emamectin 21Nov2012 2012 doi:10.2903/j.efsa.2012.2955
+Emamectin 605-015-1 119791-41-2 single chemical entity Component is part of a group assessment Emamectin benzoate 155569-91-8 - Not in list C56H81NO15 CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)[NH2+]C)OC)OC)C)C.C1=CC=C(C=C1)C(=O)[O-] InChI=1S/C49H75NO13.C7H6O2/c1-12-26(2)44-29(5)18-19-48(63-44)24-35-21-34(62-48)17-16-28(4)43(27(3)14-13-15-33-25-56-46-42(51)30(6)20-36(47(52)59-35)49(33,46)53)60-40-23-38(55-11)45(32(8)58-40)61-39-22-37(54-10)41(50-9)31(7)57-39;8-7(9)6-4-2-1-3-5-6/h13-16,18-20,26-27,29,31-32,34-46,50-51,53H,12,17,21-25H2,1-11H3;1-5H,(H,8,9)/b14-13+,28-16+,33-15+;/t26-,27-,29-,31-,32-,34+,35-,36-,37-,38-,39-,40-,41-,42+,43-,44+,45-,46+,48+,49+;/m0./s1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable House mouse (as animal) CD-1 10 Male oral: gavage 12.0000000000 h yes not applicable Negative RMS: The Netherlands Emamectin 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance emamectin 21Nov2012 2012 doi:10.2903/j.efsa.2012.2955
+Emamectin 605-015-1 119791-41-2 single chemical entity Component is part of a group assessment Emamectin benzoate 155569-91-8 - Not in list C56H81NO15 CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)[NH2+]C)OC)OC)C)C.C1=CC=C(C=C1)C(=O)[O-] InChI=1S/C49H75NO13.C7H6O2/c1-12-26(2)44-29(5)18-19-48(63-44)24-35-21-34(62-48)17-16-28(4)43(27(3)14-13-15-33-25-56-46-42(51)30(6)20-36(47(52)59-35)49(33,46)53)60-40-23-38(55-11)45(32(8)58-40)61-39-22-37(54-10)41(50-9)31(7)57-39;8-7(9)6-4-2-1-3-5-6/h13-16,18-20,26-27,29,31-32,34-46,50-51,53H,12,17,21-25H2,1-11H3;1-5H,(H,8,9)/b14-13+,28-16+,33-15+;/t26-,27-,29-,31-,32-,34+,35-,36-,37-,38-,39-,40-,41-,42+,43-,44+,45-,46+,48+,49+;/m0./s1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable House mouse (as animal) CD-1 10 Male oral: gavage 6.0000000000 h yes not applicable Negative RMS: The Netherlands Emamectin 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance emamectin 21Nov2012 2012 doi:10.2903/j.efsa.2012.2955
+Bispyribac-sodium 125401-92-5 single chemical entity Component is identical to the substance Bispyribac-sodium 125401-92-5 Sodium;2,6-bis[(4,6-dimethoxypyrimidin-2-yl)oxy]benzoate Not in list C19H17N4NaO8 COC1=CC(=NC(=N1)OC2=C(C(=CC=C2)OC3=NC(=CC(=N3)OC)OC)C(=O)[O-])OC.[Na+] InChI=1S/C19H18N4O8.Na/c1-26-12-8-13(27-2)21-18(20-12)30-10-6-5-7-11(16(10)17(24)25)31-19-22-14(28-3)9-15(23-19)29-4;/h5-9H,1-4H3,(H,24,25);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is identical to the substance Bispyribac-sodium 125401-92-5 Sodium;2,6-bis[(4,6-dimethoxypyrimidin-2-yl)oxy]benzoate Not in list C19H17N4NaO8 COC1=CC(=NC(=N1)OC2=C(C(=CC=C2)OC3=NC(=CC(=N3)OC)OC)C(=O)[O-])OC.[Na+] InChI=1S/C19H18N4O8.Na/c1-26-12-8-13(27-2)21-18(20-12)30-10-6-5-7-11(16(10)17(24)25)31-19-22-14(28-3)9-15(23-19)29-4;/h5-9H,1-4H3,(H,24,25);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is identical to the substance Bispyribac-sodium 125401-92-5 Sodium;2,6-bis[(4,6-dimethoxypyrimidin-2-yl)oxy]benzoate Not in list C19H17N4NaO8 COC1=CC(=NC(=N1)OC2=C(C(=CC=C2)OC3=NC(=CC(=N3)OC)OC)C(=O)[O-])OC.[Na+] InChI=1S/C19H18N4O8.Na/c1-26-12-8-13(27-2)21-18(20-12)30-10-6-5-7-11(16(10)17(24)25)31-19-22-14(28-3)9-15(23-19)29-4;/h5-9H,1-4H3,(H,24,25);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is identical to the substance Bispyribac-sodium 125401-92-5 Sodium;2,6-bis[(4,6-dimethoxypyrimidin-2-yl)oxy]benzoate Not in list C19H17N4NaO8 COC1=CC(=NC(=N1)OC2=C(C(=CC=C2)OC3=NC(=CC(=N3)OC)OC)C(=O)[O-])OC.[Na+] InChI=1S/C19H18N4O8.Na/c1-26-12-8-13(27-2)21-18(20-12)30-10-6-5-7-11(16(10)17(24)25)31-19-22-14(28-3)9-15(23-19)29-4;/h5-9H,1-4H3,(H,24,25);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is identical to the substance Bispyribac-sodium 125401-92-5 Sodium;2,6-bis[(4,6-dimethoxypyrimidin-2-yl)oxy]benzoate Not in list C19H17N4NaO8 COC1=CC(=NC(=N1)OC2=C(C(=CC=C2)OC3=NC(=CC(=N3)OC)OC)C(=O)[O-])OC.[Na+] InChI=1S/C19H18N4O8.Na/c1-26-12-8-13(27-2)21-18(20-12)30-10-6-5-7-11(16(10)17(24)25)31-19-22-14(28-3)9-15(23-19)29-4;/h5-9H,1-4H3,(H,24,25);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is identical to the substance Bispyribac-sodium 125401-92-5 Sodium;2,6-bis[(4,6-dimethoxypyrimidin-2-yl)oxy]benzoate Not in list C19H17N4NaO8 COC1=CC(=NC(=N1)OC2=C(C(=CC=C2)OC3=NC(=CC(=N3)OC)OC)C(=O)[O-])OC.[Na+] InChI=1S/C19H18N4O8.Na/c1-26-12-8-13(27-2)21-18(20-12)30-10-6-5-7-11(16(10)17(24)25)31-19-22-14(28-3)9-15(23-19)29-4;/h5-9H,1-4H3,(H,24,25);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is identical to the substance Bispyribac-sodium 125401-92-5 Sodium;2,6-bis[(4,6-dimethoxypyrimidin-2-yl)oxy]benzoate Not in list C19H17N4NaO8 COC1=CC(=NC(=N1)OC2=C(C(=CC=C2)OC3=NC(=CC(=N3)OC)OC)C(=O)[O-])OC.[Na+] InChI=1S/C19H18N4O8.Na/c1-26-12-8-13(27-2)21-18(20-12)30-10-6-5-7-11(16(10)17(24)25)31-19-22-14(28-3)9-15(23-19)29-4;/h5-9H,1-4H3,(H,24,25);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is identical to the substance Bispyribac-sodium 125401-92-5 Sodium;2,6-bis[(4,6-dimethoxypyrimidin-2-yl)oxy]benzoate Not in list C19H17N4NaO8 COC1=CC(=NC(=N1)OC2=C(C(=CC=C2)OC3=NC(=CC(=N3)OC)OC)C(=O)[O-])OC.[Na+] InChI=1S/C19H18N4O8.Na/c1-26-12-8-13(27-2)21-18(20-12)30-10-6-5-7-11(16(10)17(24)25)31-19-22-14(28-3)9-15(23-19)29-4;/h5-9H,1-4H3,(H,24,25);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is identical to the substance Bispyribac-sodium 125401-92-5 Sodium;2,6-bis[(4,6-dimethoxypyrimidin-2-yl)oxy]benzoate Not in list C19H17N4NaO8 COC1=CC(=NC(=N1)OC2=C(C(=CC=C2)OC3=NC(=CC(=N3)OC)OC)C(=O)[O-])OC.[Na+] InChI=1S/C19H18N4O8.Na/c1-26-12-8-13(27-2)21-18(20-12)30-10-6-5-7-11(16(10)17(24)25)31-19-22-14(28-3)9-15(23-19)29-4;/h5-9H,1-4H3,(H,24,25);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is identical to the substance Bispyribac-sodium 125401-92-5 Sodium;2,6-bis[(4,6-dimethoxypyrimidin-2-yl)oxy]benzoate Not in list C19H17N4NaO8 COC1=CC(=NC(=N1)OC2=C(C(=CC=C2)OC3=NC(=CC(=N3)OC)OC)C(=O)[O-])OC.[Na+] InChI=1S/C19H18N4O8.Na/c1-26-12-8-13(27-2)21-18(20-12)30-10-6-5-7-11(16(10)17(24)25)31-19-22-14(28-3)9-15(23-19)29-4;/h5-9H,1-4H3,(H,24,25);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is identical to the substance Bispyribac-sodium 125401-92-5 Sodium;2,6-bis[(4,6-dimethoxypyrimidin-2-yl)oxy]benzoate Not in list C19H17N4NaO8 COC1=CC(=NC(=N1)OC2=C(C(=CC=C2)OC3=NC(=CC(=N3)OC)OC)C(=O)[O-])OC.[Na+] InChI=1S/C19H18N4O8.Na/c1-26-12-8-13(27-2)21-18(20-12)30-10-6-5-7-11(16(10)17(24)25)31-19-22-14(28-3)9-15(23-19)29-4;/h5-9H,1-4H3,(H,24,25);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is identical to the substance Bispyribac-sodium 125401-92-5 Sodium;2,6-bis[(4,6-dimethoxypyrimidin-2-yl)oxy]benzoate Not in list C19H17N4NaO8 COC1=CC(=NC(=N1)OC2=C(C(=CC=C2)OC3=NC(=CC(=N3)OC)OC)C(=O)[O-])OC.[Na+] InChI=1S/C19H18N4O8.Na/c1-26-12-8-13(27-2)21-18(20-12)30-10-6-5-7-11(16(10)17(24)25)31-19-22-14(28-3)9-15(23-19)29-4;/h5-9H,1-4H3,(H,24,25);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is identical to the substance Bispyribac-sodium 125401-92-5 Sodium;2,6-bis[(4,6-dimethoxypyrimidin-2-yl)oxy]benzoate Not in list C19H17N4NaO8 COC1=CC(=NC(=N1)OC2=C(C(=CC=C2)OC3=NC(=CC(=N3)OC)OC)C(=O)[O-])OC.[Na+] InChI=1S/C19H18N4O8.Na/c1-26-12-8-13(27-2)21-18(20-12)30-10-6-5-7-11(16(10)17(24)25)31-19-22-14(28-3)9-15(23-19)29-4;/h5-9H,1-4H3,(H,24,25);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data with Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is identical to the substance Bispyribac-sodium 125401-92-5 Sodium;2,6-bis[(4,6-dimethoxypyrimidin-2-yl)oxy]benzoate Not in list C19H17N4NaO8 COC1=CC(=NC(=N1)OC2=C(C(=CC=C2)OC3=NC(=CC(=N3)OC)OC)C(=O)[O-])OC.[Na+] InChI=1S/C19H18N4O8.Na/c1-26-12-8-13(27-2)21-18(20-12)30-10-6-5-7-11(16(10)17(24)25)31-19-22-14(28-3)9-15(23-19)29-4;/h5-9H,1-4H3,(H,24,25);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data without Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is identical to the substance Bispyribac-sodium 125401-92-5 Sodium;2,6-bis[(4,6-dimethoxypyrimidin-2-yl)oxy]benzoate Not in list C19H17N4NaO8 COC1=CC(=NC(=N1)OC2=C(C(=CC=C2)OC3=NC(=CC(=N3)OC)OC)C(=O)[O-])OC.[Na+] InChI=1S/C19H18N4O8.Na/c1-26-12-8-13(27-2)21-18(20-12)30-10-6-5-7-11(16(10)17(24)25)31-19-22-14(28-3)9-15(23-19)29-4;/h5-9H,1-4H3,(H,24,25);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported no data without Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is identical to the substance Bispyribac-sodium 125401-92-5 Sodium;2,6-bis[(4,6-dimethoxypyrimidin-2-yl)oxy]benzoate Not in list C19H17N4NaO8 COC1=CC(=NC(=N1)OC2=C(C(=CC=C2)OC3=NC(=CC(=N3)OC)OC)C(=O)[O-])OC.[Na+] InChI=1S/C19H18N4O8.Na/c1-26-12-8-13(27-2)21-18(20-12)30-10-6-5-7-11(16(10)17(24)25)31-19-22-14(28-3)9-15(23-19)29-4;/h5-9H,1-4H3,(H,24,25);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported no data with Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is identical to the substance Bispyribac-sodium 125401-92-5 Sodium;2,6-bis[(4,6-dimethoxypyrimidin-2-yl)oxy]benzoate Not in list C19H17N4NaO8 COC1=CC(=NC(=N1)OC2=C(C(=CC=C2)OC3=NC(=CC(=N3)OC)OC)C(=O)[O-])OC.[Na+] InChI=1S/C19H18N4O8.Na/c1-26-12-8-13(27-2)21-18(20-12)30-10-6-5-7-11(16(10)17(24)25)31-19-22-14(28-3)9-15(23-19)29-4;/h5-9H,1-4H3,(H,24,25);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported no data without Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is identical to the substance Bispyribac-sodium 125401-92-5 Sodium;2,6-bis[(4,6-dimethoxypyrimidin-2-yl)oxy]benzoate Not in list C19H17N4NaO8 COC1=CC(=NC(=N1)OC2=C(C(=CC=C2)OC3=NC(=CC(=N3)OC)OC)C(=O)[O-])OC.[Na+] InChI=1S/C19H18N4O8.Na/c1-26-12-8-13(27-2)21-18(20-12)30-10-6-5-7-11(16(10)17(24)25)31-19-22-14(28-3)9-15(23-19)29-4;/h5-9H,1-4H3,(H,24,25);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) ICR 10 Male/Female oral: gavage 24.0000000000 h no data not applicable Negative no evidence RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is identical to the substance Bispyribac-sodium 125401-92-5 Sodium;2,6-bis[(4,6-dimethoxypyrimidin-2-yl)oxy]benzoate Not in list C19H17N4NaO8 COC1=CC(=NC(=N1)OC2=C(C(=CC=C2)OC3=NC(=CC(=N3)OC)OC)C(=O)[O-])OC.[Na+] InChI=1S/C19H18N4O8.Na/c1-26-12-8-13(27-2)21-18(20-12)30-10-6-5-7-11(16(10)17(24)25)31-19-22-14(28-3)9-15(23-19)29-4;/h5-9H,1-4H3,(H,24,25);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) ICR 10 Male/Female oral: gavage 48.0000000000 h no data not applicable Negative no evidence RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is identical to the substance Bispyribac-sodium 125401-92-5 Sodium;2,6-bis[(4,6-dimethoxypyrimidin-2-yl)oxy]benzoate Not in list C19H17N4NaO8 COC1=CC(=NC(=N1)OC2=C(C(=CC=C2)OC3=NC(=CC(=N3)OC)OC)C(=O)[O-])OC.[Na+] InChI=1S/C19H18N4O8.Na/c1-26-12-8-13(27-2)21-18(20-12)30-10-6-5-7-11(16(10)17(24)25)31-19-22-14(28-3)9-15(23-19)29-4;/h5-9H,1-4H3,(H,24,25);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) ICR 10 Male/Female oral: gavage 72.0000000000 h no data not applicable Negative no evidence RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance 2-hydroxy-4,6-dimethoxypyrimidine 13223-26-2 4,6-dimethoxy-1H-pyrimidin-2-one Not in list C6H8N2O3 COC1=CC(=NC(=O)N1)OC InChI=1S/C6H8N2O3/c1-10-4-3-5(11-2)8-6(9)7-4/h3H,1-2H3,(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance 2-hydroxy-4,6-dimethoxypyrimidine 13223-26-2 4,6-dimethoxy-1H-pyrimidin-2-one Not in list C6H8N2O3 COC1=CC(=NC(=O)N1)OC InChI=1S/C6H8N2O3/c1-10-4-3-5(11-2)8-6(9)7-4/h3H,1-2H3,(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance 2-hydroxy-4,6-dimethoxypyrimidine 13223-26-2 4,6-dimethoxy-1H-pyrimidin-2-one Not in list C6H8N2O3 COC1=CC(=NC(=O)N1)OC InChI=1S/C6H8N2O3/c1-10-4-3-5(11-2)8-6(9)7-4/h3H,1-2H3,(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance 2-hydroxy-4,6-dimethoxypyrimidine 13223-26-2 4,6-dimethoxy-1H-pyrimidin-2-one Not in list C6H8N2O3 COC1=CC(=NC(=O)N1)OC InChI=1S/C6H8N2O3/c1-10-4-3-5(11-2)8-6(9)7-4/h3H,1-2H3,(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance 2-hydroxy-4,6-dimethoxypyrimidine 13223-26-2 4,6-dimethoxy-1H-pyrimidin-2-one Not in list C6H8N2O3 COC1=CC(=NC(=O)N1)OC InChI=1S/C6H8N2O3/c1-10-4-3-5(11-2)8-6(9)7-4/h3H,1-2H3,(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance 2-hydroxy-4,6-dimethoxypyrimidine 13223-26-2 4,6-dimethoxy-1H-pyrimidin-2-one Not in list C6H8N2O3 COC1=CC(=NC(=O)N1)OC InChI=1S/C6H8N2O3/c1-10-4-3-5(11-2)8-6(9)7-4/h3H,1-2H3,(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance 2-hydroxy-4,6-dimethoxypyrimidine 13223-26-2 4,6-dimethoxy-1H-pyrimidin-2-one Not in list C6H8N2O3 COC1=CC(=NC(=O)N1)OC InChI=1S/C6H8N2O3/c1-10-4-3-5(11-2)8-6(9)7-4/h3H,1-2H3,(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance 2-hydroxy-4,6-dimethoxypyrimidine 13223-26-2 4,6-dimethoxy-1H-pyrimidin-2-one Not in list C6H8N2O3 COC1=CC(=NC(=O)N1)OC InChI=1S/C6H8N2O3/c1-10-4-3-5(11-2)8-6(9)7-4/h3H,1-2H3,(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance 2-hydroxy-4,6-dimethoxypyrimidine 13223-26-2 4,6-dimethoxy-1H-pyrimidin-2-one Not in list C6H8N2O3 COC1=CC(=NC(=O)N1)OC InChI=1S/C6H8N2O3/c1-10-4-3-5(11-2)8-6(9)7-4/h3H,1-2H3,(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance 2-hydroxy-4,6-dimethoxypyrimidine 13223-26-2 4,6-dimethoxy-1H-pyrimidin-2-one Not in list C6H8N2O3 COC1=CC(=NC(=O)N1)OC InChI=1S/C6H8N2O3/c1-10-4-3-5(11-2)8-6(9)7-4/h3H,1-2H3,(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance 2,4-dihydroxy-6-methoxypyrimidine 29458-38-6 6-methoxy-1H-pyrimidine-2,4-dione Not in list C5H6N2O3 COC1=CC(=O)NC(=O)N1 InChI=1S/C5H6N2O3/c1-10-4-2-3(8)6-5(9)7-4/h2H,1H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance 2,4-dihydroxy-6-methoxypyrimidine 29458-38-6 6-methoxy-1H-pyrimidine-2,4-dione Not in list C5H6N2O3 COC1=CC(=O)NC(=O)N1 InChI=1S/C5H6N2O3/c1-10-4-2-3(8)6-5(9)7-4/h2H,1H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance 2,4-dihydroxy-6-methoxypyrimidine 29458-38-6 6-methoxy-1H-pyrimidine-2,4-dione Not in list C5H6N2O3 COC1=CC(=O)NC(=O)N1 InChI=1S/C5H6N2O3/c1-10-4-2-3(8)6-5(9)7-4/h2H,1H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance 2,4-dihydroxy-6-methoxypyrimidine 29458-38-6 6-methoxy-1H-pyrimidine-2,4-dione Not in list C5H6N2O3 COC1=CC(=O)NC(=O)N1 InChI=1S/C5H6N2O3/c1-10-4-2-3(8)6-5(9)7-4/h2H,1H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance 2,4-dihydroxy-6-methoxypyrimidine 29458-38-6 6-methoxy-1H-pyrimidine-2,4-dione Not in list C5H6N2O3 COC1=CC(=O)NC(=O)N1 InChI=1S/C5H6N2O3/c1-10-4-2-3(8)6-5(9)7-4/h2H,1H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance 2,4-dihydroxy-6-methoxypyrimidine 29458-38-6 6-methoxy-1H-pyrimidine-2,4-dione Not in list C5H6N2O3 COC1=CC(=O)NC(=O)N1 InChI=1S/C5H6N2O3/c1-10-4-2-3(8)6-5(9)7-4/h2H,1H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance 2,4-dihydroxy-6-methoxypyrimidine 29458-38-6 6-methoxy-1H-pyrimidine-2,4-dione Not in list C5H6N2O3 COC1=CC(=O)NC(=O)N1 InChI=1S/C5H6N2O3/c1-10-4-2-3(8)6-5(9)7-4/h2H,1H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance 2,4-dihydroxy-6-methoxypyrimidine 29458-38-6 6-methoxy-1H-pyrimidine-2,4-dione Not in list C5H6N2O3 COC1=CC(=O)NC(=O)N1 InChI=1S/C5H6N2O3/c1-10-4-2-3(8)6-5(9)7-4/h2H,1H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance 2,4-dihydroxy-6-methoxypyrimidine 29458-38-6 6-methoxy-1H-pyrimidine-2,4-dione Not in list C5H6N2O3 COC1=CC(=O)NC(=O)N1 InChI=1S/C5H6N2O3/c1-10-4-2-3(8)6-5(9)7-4/h2H,1H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance 2,4-dihydroxy-6-methoxypyrimidine 29458-38-6 6-methoxy-1H-pyrimidine-2,4-dione Not in list C5H6N2O3 COC1=CC(=O)NC(=O)N1 InChI=1S/C5H6N2O3/c1-10-4-2-3(8)6-5(9)7-4/h2H,1H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance 2,4-dihydroxy-6-methoxypyrimidine 29458-38-6 6-methoxy-1H-pyrimidine-2,4-dione Not in list C5H6N2O3 COC1=CC(=O)NC(=O)N1 InChI=1S/C5H6N2O3/c1-10-4-2-3(8)6-5(9)7-4/h2H,1H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance 2,4-dihydroxy-6-methoxypyrimidine 29458-38-6 6-methoxy-1H-pyrimidine-2,4-dione Not in list C5H6N2O3 COC1=CC(=O)NC(=O)N1 InChI=1S/C5H6N2O3/c1-10-4-2-3(8)6-5(9)7-4/h2H,1H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance 2-(4,6-dimethoxy-5-hydroxypyrimidin-2-yl)oxy-6-(4,6-dimethoxypyrimidin-2-yl)oxybenzoic acid 2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-[(5-hydroxy-4,6-dimethoxypyrimidin-2-yl)oxy]benzoic acid Not in list C19H18N4O9 COc1nc(nc(OC)c1)Oc3cccc(Oc2nc(OC)c(O)c(OC)n2)c3C(=O)O InChI=1/C19H18N4O9/c1-27-11-8-12(28-2)21-18(20-11)31-9-6-5-7-10(13(9)17(25)26)32-19-22-15(29-3)14(24)16(23-19)30-4/h5-8,24H,1-4H3,(H,25,26) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance 2-(4,6-dimethoxy-5-hydroxypyrimidin-2-yl)oxy-6-(4,6-dimethoxypyrimidin-2-yl)oxybenzoic acid 2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-[(5-hydroxy-4,6-dimethoxypyrimidin-2-yl)oxy]benzoic acid Not in list C19H18N4O9 COc1nc(nc(OC)c1)Oc3cccc(Oc2nc(OC)c(O)c(OC)n2)c3C(=O)O InChI=1/C19H18N4O9/c1-27-11-8-12(28-2)21-18(20-11)31-9-6-5-7-10(13(9)17(25)26)32-19-22-15(29-3)14(24)16(23-19)30-4/h5-8,24H,1-4H3,(H,25,26) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance 2-(4,6-dimethoxy-5-hydroxypyrimidin-2-yl)oxy-6-(4,6-dimethoxypyrimidin-2-yl)oxybenzoic acid 2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-[(5-hydroxy-4,6-dimethoxypyrimidin-2-yl)oxy]benzoic acid Not in list C19H18N4O9 COc1nc(nc(OC)c1)Oc3cccc(Oc2nc(OC)c(O)c(OC)n2)c3C(=O)O InChI=1/C19H18N4O9/c1-27-11-8-12(28-2)21-18(20-11)31-9-6-5-7-10(13(9)17(25)26)32-19-22-15(29-3)14(24)16(23-19)30-4/h5-8,24H,1-4H3,(H,25,26) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance 2-(4,6-dimethoxy-5-hydroxypyrimidin-2-yl)oxy-6-(4,6-dimethoxypyrimidin-2-yl)oxybenzoic acid 2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-[(5-hydroxy-4,6-dimethoxypyrimidin-2-yl)oxy]benzoic acid Not in list C19H18N4O9 COc1nc(nc(OC)c1)Oc3cccc(Oc2nc(OC)c(O)c(OC)n2)c3C(=O)O InChI=1/C19H18N4O9/c1-27-11-8-12(28-2)21-18(20-11)31-9-6-5-7-10(13(9)17(25)26)32-19-22-15(29-3)14(24)16(23-19)30-4/h5-8,24H,1-4H3,(H,25,26) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance 2-(4,6-dimethoxy-5-hydroxypyrimidin-2-yl)oxy-6-(4,6-dimethoxypyrimidin-2-yl)oxybenzoic acid 2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-[(5-hydroxy-4,6-dimethoxypyrimidin-2-yl)oxy]benzoic acid Not in list C19H18N4O9 COc1nc(nc(OC)c1)Oc3cccc(Oc2nc(OC)c(O)c(OC)n2)c3C(=O)O InChI=1/C19H18N4O9/c1-27-11-8-12(28-2)21-18(20-11)31-9-6-5-7-10(13(9)17(25)26)32-19-22-15(29-3)14(24)16(23-19)30-4/h5-8,24H,1-4H3,(H,25,26) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance 2-(4,6-dimethoxy-5-hydroxypyrimidin-2-yl)oxy-6-(4,6-dimethoxypyrimidin-2-yl)oxybenzoic acid 2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-[(5-hydroxy-4,6-dimethoxypyrimidin-2-yl)oxy]benzoic acid Not in list C19H18N4O9 COc1nc(nc(OC)c1)Oc3cccc(Oc2nc(OC)c(O)c(OC)n2)c3C(=O)O InChI=1/C19H18N4O9/c1-27-11-8-12(28-2)21-18(20-11)31-9-6-5-7-10(13(9)17(25)26)32-19-22-15(29-3)14(24)16(23-19)30-4/h5-8,24H,1-4H3,(H,25,26) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance 2-(4,6-dimethoxy-5-hydroxypyrimidin-2-yl)oxy-6-(4,6-dimethoxypyrimidin-2-yl)oxybenzoic acid 2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-[(5-hydroxy-4,6-dimethoxypyrimidin-2-yl)oxy]benzoic acid Not in list C19H18N4O9 COc1nc(nc(OC)c1)Oc3cccc(Oc2nc(OC)c(O)c(OC)n2)c3C(=O)O InChI=1/C19H18N4O9/c1-27-11-8-12(28-2)21-18(20-11)31-9-6-5-7-10(13(9)17(25)26)32-19-22-15(29-3)14(24)16(23-19)30-4/h5-8,24H,1-4H3,(H,25,26) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance 2-(4,6-dimethoxy-5-hydroxypyrimidin-2-yl)oxy-6-(4,6-dimethoxypyrimidin-2-yl)oxybenzoic acid 2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-[(5-hydroxy-4,6-dimethoxypyrimidin-2-yl)oxy]benzoic acid Not in list C19H18N4O9 COc1nc(nc(OC)c1)Oc3cccc(Oc2nc(OC)c(O)c(OC)n2)c3C(=O)O InChI=1/C19H18N4O9/c1-27-11-8-12(28-2)21-18(20-11)31-9-6-5-7-10(13(9)17(25)26)32-19-22-15(29-3)14(24)16(23-19)30-4/h5-8,24H,1-4H3,(H,25,26) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance 2-(4,6-dimethoxy-5-hydroxypyrimidin-2-yl)oxy-6-(4,6-dimethoxypyrimidin-2-yl)oxybenzoic acid 2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-[(5-hydroxy-4,6-dimethoxypyrimidin-2-yl)oxy]benzoic acid Not in list C19H18N4O9 COc1nc(nc(OC)c1)Oc3cccc(Oc2nc(OC)c(O)c(OC)n2)c3C(=O)O InChI=1/C19H18N4O9/c1-27-11-8-12(28-2)21-18(20-11)31-9-6-5-7-10(13(9)17(25)26)32-19-22-15(29-3)14(24)16(23-19)30-4/h5-8,24H,1-4H3,(H,25,26) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance 2-(4,6-dimethoxy-5-hydroxypyrimidin-2-yl)oxy-6-(4,6-dimethoxypyrimidin-2-yl)oxybenzoic acid 2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-[(5-hydroxy-4,6-dimethoxypyrimidin-2-yl)oxy]benzoic acid Not in list C19H18N4O9 COc1nc(nc(OC)c1)Oc3cccc(Oc2nc(OC)c(O)c(OC)n2)c3C(=O)O InChI=1/C19H18N4O9/c1-27-11-8-12(28-2)21-18(20-11)31-9-6-5-7-10(13(9)17(25)26)32-19-22-15(29-3)14(24)16(23-19)30-4/h5-8,24H,1-4H3,(H,25,26) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance 2-(4,6-dimethoxy-5-hydroxypyrimidin-2-yl)oxy-6-(4,6-dimethoxypyrimidin-2-yl)oxybenzoic acid 2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-[(5-hydroxy-4,6-dimethoxypyrimidin-2-yl)oxy]benzoic acid Not in list C19H18N4O9 COc1nc(nc(OC)c1)Oc3cccc(Oc2nc(OC)c(O)c(OC)n2)c3C(=O)O InChI=1/C19H18N4O9/c1-27-11-8-12(28-2)21-18(20-11)31-9-6-5-7-10(13(9)17(25)26)32-19-22-15(29-3)14(24)16(23-19)30-4/h5-8,24H,1-4H3,(H,25,26) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance 2-(4,6-dimethoxy-5-hydroxypyrimidin-2-yl)oxy-6-(4,6-dimethoxypyrimidin-2-yl)oxybenzoic acid 2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-[(5-hydroxy-4,6-dimethoxypyrimidin-2-yl)oxy]benzoic acid Not in list C19H18N4O9 COc1nc(nc(OC)c1)Oc3cccc(Oc2nc(OC)c(O)c(OC)n2)c3C(=O)O InChI=1/C19H18N4O9/c1-27-11-8-12(28-2)21-18(20-11)31-9-6-5-7-10(13(9)17(25)26)32-19-22-15(29-3)14(24)16(23-19)30-4/h5-8,24H,1-4H3,(H,25,26) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance sodium 2-hydroxy-6-(4-hydroxy-6-methoxypyrimidin-2-yl)oxybenzoate sodium 2-hydroxy-6-[(4-hydroxy-6-methoxypyrimidin-2-yl)oxy]benzoate Not in list C12H5N2NaO6 [Na+].[O-]C(=O)c2c(Oc1nc(O)cc(OC)n1)cccc2O InChI=1/C12H10N2O6.Na/c1-19-9-5-8(16)13-12(14-9)20-7-4-2-3-6(15)10(7)11(17)18;/h2-5,15H,1H3,(H,17,18)(H,13,14,16);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance sodium 2-hydroxy-6-(4-hydroxy-6-methoxypyrimidin-2-yl)oxybenzoate sodium 2-hydroxy-6-[(4-hydroxy-6-methoxypyrimidin-2-yl)oxy]benzoate Not in list C12H5N2NaO6 [Na+].[O-]C(=O)c2c(Oc1nc(O)cc(OC)n1)cccc2O InChI=1/C12H10N2O6.Na/c1-19-9-5-8(16)13-12(14-9)20-7-4-2-3-6(15)10(7)11(17)18;/h2-5,15H,1H3,(H,17,18)(H,13,14,16);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance sodium 2-hydroxy-6-(4-hydroxy-6-methoxypyrimidin-2-yl)oxybenzoate sodium 2-hydroxy-6-[(4-hydroxy-6-methoxypyrimidin-2-yl)oxy]benzoate Not in list C12H5N2NaO6 [Na+].[O-]C(=O)c2c(Oc1nc(O)cc(OC)n1)cccc2O InChI=1/C12H10N2O6.Na/c1-19-9-5-8(16)13-12(14-9)20-7-4-2-3-6(15)10(7)11(17)18;/h2-5,15H,1H3,(H,17,18)(H,13,14,16);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance sodium 2-hydroxy-6-(4-hydroxy-6-methoxypyrimidin-2-yl)oxybenzoate sodium 2-hydroxy-6-[(4-hydroxy-6-methoxypyrimidin-2-yl)oxy]benzoate Not in list C12H5N2NaO6 [Na+].[O-]C(=O)c2c(Oc1nc(O)cc(OC)n1)cccc2O InChI=1/C12H10N2O6.Na/c1-19-9-5-8(16)13-12(14-9)20-7-4-2-3-6(15)10(7)11(17)18;/h2-5,15H,1H3,(H,17,18)(H,13,14,16);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance sodium 2-hydroxy-6-(4-hydroxy-6-methoxypyrimidin-2-yl)oxybenzoate sodium 2-hydroxy-6-[(4-hydroxy-6-methoxypyrimidin-2-yl)oxy]benzoate Not in list C12H5N2NaO6 [Na+].[O-]C(=O)c2c(Oc1nc(O)cc(OC)n1)cccc2O InChI=1/C12H10N2O6.Na/c1-19-9-5-8(16)13-12(14-9)20-7-4-2-3-6(15)10(7)11(17)18;/h2-5,15H,1H3,(H,17,18)(H,13,14,16);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance sodium 2-hydroxy-6-(4-hydroxy-6-methoxypyrimidin-2-yl)oxybenzoate sodium 2-hydroxy-6-[(4-hydroxy-6-methoxypyrimidin-2-yl)oxy]benzoate Not in list C12H5N2NaO6 [Na+].[O-]C(=O)c2c(Oc1nc(O)cc(OC)n1)cccc2O InChI=1/C12H10N2O6.Na/c1-19-9-5-8(16)13-12(14-9)20-7-4-2-3-6(15)10(7)11(17)18;/h2-5,15H,1H3,(H,17,18)(H,13,14,16);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance sodium 2-hydroxy-6-(4-hydroxy-6-methoxypyrimidin-2-yl)oxybenzoate sodium 2-hydroxy-6-[(4-hydroxy-6-methoxypyrimidin-2-yl)oxy]benzoate Not in list C12H5N2NaO6 [Na+].[O-]C(=O)c2c(Oc1nc(O)cc(OC)n1)cccc2O InChI=1/C12H10N2O6.Na/c1-19-9-5-8(16)13-12(14-9)20-7-4-2-3-6(15)10(7)11(17)18;/h2-5,15H,1H3,(H,17,18)(H,13,14,16);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance sodium 2-hydroxy-6-(4-hydroxy-6-methoxypyrimidin-2-yl)oxybenzoate sodium 2-hydroxy-6-[(4-hydroxy-6-methoxypyrimidin-2-yl)oxy]benzoate Not in list C12H5N2NaO6 [Na+].[O-]C(=O)c2c(Oc1nc(O)cc(OC)n1)cccc2O InChI=1/C12H10N2O6.Na/c1-19-9-5-8(16)13-12(14-9)20-7-4-2-3-6(15)10(7)11(17)18;/h2-5,15H,1H3,(H,17,18)(H,13,14,16);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance sodium 2-hydroxy-6-(4-hydroxy-6-methoxypyrimidin-2-yl)oxybenzoate sodium 2-hydroxy-6-[(4-hydroxy-6-methoxypyrimidin-2-yl)oxy]benzoate Not in list C12H5N2NaO6 [Na+].[O-]C(=O)c2c(Oc1nc(O)cc(OC)n1)cccc2O InChI=1/C12H10N2O6.Na/c1-19-9-5-8(16)13-12(14-9)20-7-4-2-3-6(15)10(7)11(17)18;/h2-5,15H,1H3,(H,17,18)(H,13,14,16);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance sodium 2-hydroxy-6-(4-hydroxy-6-methoxypyrimidin-2-yl)oxybenzoate sodium 2-hydroxy-6-[(4-hydroxy-6-methoxypyrimidin-2-yl)oxy]benzoate Not in list C12H5N2NaO6 [Na+].[O-]C(=O)c2c(Oc1nc(O)cc(OC)n1)cccc2O InChI=1/C12H10N2O6.Na/c1-19-9-5-8(16)13-12(14-9)20-7-4-2-3-6(15)10(7)11(17)18;/h2-5,15H,1H3,(H,17,18)(H,13,14,16);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance sodium 2-hydroxy-6-(4-hydroxy-6-methoxypyrimidin-2-yl)oxybenzoate sodium 2-hydroxy-6-[(4-hydroxy-6-methoxypyrimidin-2-yl)oxy]benzoate Not in list C12H5N2NaO6 [Na+].[O-]C(=O)c2c(Oc1nc(O)cc(OC)n1)cccc2O InChI=1/C12H10N2O6.Na/c1-19-9-5-8(16)13-12(14-9)20-7-4-2-3-6(15)10(7)11(17)18;/h2-5,15H,1H3,(H,17,18)(H,13,14,16);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance sodium 2-hydroxy-6-(4-hydroxy-6-methoxypyrimidin-2-yl)oxybenzoate sodium 2-hydroxy-6-[(4-hydroxy-6-methoxypyrimidin-2-yl)oxy]benzoate Not in list C12H5N2NaO6 [Na+].[O-]C(=O)c2c(Oc1nc(O)cc(OC)n1)cccc2O InChI=1/C12H10N2O6.Na/c1-19-9-5-8(16)13-12(14-9)20-7-4-2-3-6(15)10(7)11(17)18;/h2-5,15H,1H3,(H,17,18)(H,13,14,16);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance 2-(4,6-dimethoxypyrimidin-2-yl)oxy-6-hydroxybenzoic acid 2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-hydroxybenzoic acid Not in list C13H12N2O3 O=C(O)c2c(Oc1nc(cc(OC)n1)OC)cccc2O InChI=1/C13H12N2O6/c1-19-9-6-10(20-2)15-13(14-9)21-8-5-3-4-7(16)11(8)12(17)18/h3-6,16H,1-2H3,(H,17,18) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance 2-(4,6-dimethoxypyrimidin-2-yl)oxy-6-hydroxybenzoic acid 2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-hydroxybenzoic acid Not in list C13H12N2O3 O=C(O)c2c(Oc1nc(cc(OC)n1)OC)cccc2O InChI=1/C13H12N2O6/c1-19-9-6-10(20-2)15-13(14-9)21-8-5-3-4-7(16)11(8)12(17)18/h3-6,16H,1-2H3,(H,17,18) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance 2-(4,6-dimethoxypyrimidin-2-yl)oxy-6-hydroxybenzoic acid 2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-hydroxybenzoic acid Not in list C13H12N2O3 O=C(O)c2c(Oc1nc(cc(OC)n1)OC)cccc2O InChI=1/C13H12N2O6/c1-19-9-6-10(20-2)15-13(14-9)21-8-5-3-4-7(16)11(8)12(17)18/h3-6,16H,1-2H3,(H,17,18) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance 2-(4,6-dimethoxypyrimidin-2-yl)oxy-6-hydroxybenzoic acid 2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-hydroxybenzoic acid Not in list C13H12N2O3 O=C(O)c2c(Oc1nc(cc(OC)n1)OC)cccc2O InChI=1/C13H12N2O6/c1-19-9-6-10(20-2)15-13(14-9)21-8-5-3-4-7(16)11(8)12(17)18/h3-6,16H,1-2H3,(H,17,18) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance 2-(4,6-dimethoxypyrimidin-2-yl)oxy-6-hydroxybenzoic acid 2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-hydroxybenzoic acid Not in list C13H12N2O3 O=C(O)c2c(Oc1nc(cc(OC)n1)OC)cccc2O InChI=1/C13H12N2O6/c1-19-9-6-10(20-2)15-13(14-9)21-8-5-3-4-7(16)11(8)12(17)18/h3-6,16H,1-2H3,(H,17,18) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance 2-(4,6-dimethoxypyrimidin-2-yl)oxy-6-hydroxybenzoic acid 2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-hydroxybenzoic acid Not in list C13H12N2O3 O=C(O)c2c(Oc1nc(cc(OC)n1)OC)cccc2O InChI=1/C13H12N2O6/c1-19-9-6-10(20-2)15-13(14-9)21-8-5-3-4-7(16)11(8)12(17)18/h3-6,16H,1-2H3,(H,17,18) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance 2-(4,6-dimethoxypyrimidin-2-yl)oxy-6-hydroxybenzoic acid 2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-hydroxybenzoic acid Not in list C13H12N2O3 O=C(O)c2c(Oc1nc(cc(OC)n1)OC)cccc2O InChI=1/C13H12N2O6/c1-19-9-6-10(20-2)15-13(14-9)21-8-5-3-4-7(16)11(8)12(17)18/h3-6,16H,1-2H3,(H,17,18) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance 2-(4,6-dimethoxypyrimidin-2-yl)oxy-6-hydroxybenzoic acid 2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-hydroxybenzoic acid Not in list C13H12N2O3 O=C(O)c2c(Oc1nc(cc(OC)n1)OC)cccc2O InChI=1/C13H12N2O6/c1-19-9-6-10(20-2)15-13(14-9)21-8-5-3-4-7(16)11(8)12(17)18/h3-6,16H,1-2H3,(H,17,18) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance 2-(4,6-dimethoxypyrimidin-2-yl)oxy-6-hydroxybenzoic acid 2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-hydroxybenzoic acid Not in list C13H12N2O3 O=C(O)c2c(Oc1nc(cc(OC)n1)OC)cccc2O InChI=1/C13H12N2O6/c1-19-9-6-10(20-2)15-13(14-9)21-8-5-3-4-7(16)11(8)12(17)18/h3-6,16H,1-2H3,(H,17,18) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance 2-(4,6-dimethoxypyrimidin-2-yl)oxy-6-hydroxybenzoic acid 2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-hydroxybenzoic acid Not in list C13H12N2O3 O=C(O)c2c(Oc1nc(cc(OC)n1)OC)cccc2O InChI=1/C13H12N2O6/c1-19-9-6-10(20-2)15-13(14-9)21-8-5-3-4-7(16)11(8)12(17)18/h3-6,16H,1-2H3,(H,17,18) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance benzoic acid, 2-[(4,6-dimethoxy-2-pyrimidinyl)oxy]-6-[(4-hydroxy-6-methoxy-2-pyrimidinyl)oxy],sodium salt sodium 2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-[(4-hydroxy-6-methoxypyrimidin-2-yl)oxy]benzoate Not in list C18H15N4NaO8 [Na+].Oc1nc(nc(OC)c1)Oc3cccc(Oc2nc(cc(OC)n2)OC)c3C([O-])=O InChI=1/C18H16N4O8.Na/c1-26-12-7-11(23)19-17(20-12)29-9-5-4-6-10(15(9)16(24)25)30-18-21-13(27-2)8-14(22-18)28-3;/h4-8H,1-3H3,(H,24,25)(H,19,20,23);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance benzoic acid, 2-[(4,6-dimethoxy-2-pyrimidinyl)oxy]-6-[(4-hydroxy-6-methoxy-2-pyrimidinyl)oxy],sodium salt sodium 2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-[(4-hydroxy-6-methoxypyrimidin-2-yl)oxy]benzoate Not in list C18H15N4NaO8 [Na+].Oc1nc(nc(OC)c1)Oc3cccc(Oc2nc(cc(OC)n2)OC)c3C([O-])=O InChI=1/C18H16N4O8.Na/c1-26-12-7-11(23)19-17(20-12)29-9-5-4-6-10(15(9)16(24)25)30-18-21-13(27-2)8-14(22-18)28-3;/h4-8H,1-3H3,(H,24,25)(H,19,20,23);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance benzoic acid, 2-[(4,6-dimethoxy-2-pyrimidinyl)oxy]-6-[(4-hydroxy-6-methoxy-2-pyrimidinyl)oxy],sodium salt sodium 2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-[(4-hydroxy-6-methoxypyrimidin-2-yl)oxy]benzoate Not in list C18H15N4NaO8 [Na+].Oc1nc(nc(OC)c1)Oc3cccc(Oc2nc(cc(OC)n2)OC)c3C([O-])=O InChI=1/C18H16N4O8.Na/c1-26-12-7-11(23)19-17(20-12)29-9-5-4-6-10(15(9)16(24)25)30-18-21-13(27-2)8-14(22-18)28-3;/h4-8H,1-3H3,(H,24,25)(H,19,20,23);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance benzoic acid, 2-[(4,6-dimethoxy-2-pyrimidinyl)oxy]-6-[(4-hydroxy-6-methoxy-2-pyrimidinyl)oxy],sodium salt sodium 2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-[(4-hydroxy-6-methoxypyrimidin-2-yl)oxy]benzoate Not in list C18H15N4NaO8 [Na+].Oc1nc(nc(OC)c1)Oc3cccc(Oc2nc(cc(OC)n2)OC)c3C([O-])=O InChI=1/C18H16N4O8.Na/c1-26-12-7-11(23)19-17(20-12)29-9-5-4-6-10(15(9)16(24)25)30-18-21-13(27-2)8-14(22-18)28-3;/h4-8H,1-3H3,(H,24,25)(H,19,20,23);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance benzoic acid, 2-[(4,6-dimethoxy-2-pyrimidinyl)oxy]-6-[(4-hydroxy-6-methoxy-2-pyrimidinyl)oxy],sodium salt sodium 2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-[(4-hydroxy-6-methoxypyrimidin-2-yl)oxy]benzoate Not in list C18H15N4NaO8 [Na+].Oc1nc(nc(OC)c1)Oc3cccc(Oc2nc(cc(OC)n2)OC)c3C([O-])=O InChI=1/C18H16N4O8.Na/c1-26-12-7-11(23)19-17(20-12)29-9-5-4-6-10(15(9)16(24)25)30-18-21-13(27-2)8-14(22-18)28-3;/h4-8H,1-3H3,(H,24,25)(H,19,20,23);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance benzoic acid, 2-[(4,6-dimethoxy-2-pyrimidinyl)oxy]-6-[(4-hydroxy-6-methoxy-2-pyrimidinyl)oxy],sodium salt sodium 2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-[(4-hydroxy-6-methoxypyrimidin-2-yl)oxy]benzoate Not in list C18H15N4NaO8 [Na+].Oc1nc(nc(OC)c1)Oc3cccc(Oc2nc(cc(OC)n2)OC)c3C([O-])=O InChI=1/C18H16N4O8.Na/c1-26-12-7-11(23)19-17(20-12)29-9-5-4-6-10(15(9)16(24)25)30-18-21-13(27-2)8-14(22-18)28-3;/h4-8H,1-3H3,(H,24,25)(H,19,20,23);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance benzoic acid, 2-[(4,6-dimethoxy-2-pyrimidinyl)oxy]-6-[(4-hydroxy-6-methoxy-2-pyrimidinyl)oxy],sodium salt sodium 2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-[(4-hydroxy-6-methoxypyrimidin-2-yl)oxy]benzoate Not in list C18H15N4NaO8 [Na+].Oc1nc(nc(OC)c1)Oc3cccc(Oc2nc(cc(OC)n2)OC)c3C([O-])=O InChI=1/C18H16N4O8.Na/c1-26-12-7-11(23)19-17(20-12)29-9-5-4-6-10(15(9)16(24)25)30-18-21-13(27-2)8-14(22-18)28-3;/h4-8H,1-3H3,(H,24,25)(H,19,20,23);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance benzoic acid, 2-[(4,6-dimethoxy-2-pyrimidinyl)oxy]-6-[(4-hydroxy-6-methoxy-2-pyrimidinyl)oxy],sodium salt sodium 2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-[(4-hydroxy-6-methoxypyrimidin-2-yl)oxy]benzoate Not in list C18H15N4NaO8 [Na+].Oc1nc(nc(OC)c1)Oc3cccc(Oc2nc(cc(OC)n2)OC)c3C([O-])=O InChI=1/C18H16N4O8.Na/c1-26-12-7-11(23)19-17(20-12)29-9-5-4-6-10(15(9)16(24)25)30-18-21-13(27-2)8-14(22-18)28-3;/h4-8H,1-3H3,(H,24,25)(H,19,20,23);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance benzoic acid, 2-[(4,6-dimethoxy-2-pyrimidinyl)oxy]-6-[(4-hydroxy-6-methoxy-2-pyrimidinyl)oxy],sodium salt sodium 2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-[(4-hydroxy-6-methoxypyrimidin-2-yl)oxy]benzoate Not in list C18H15N4NaO8 [Na+].Oc1nc(nc(OC)c1)Oc3cccc(Oc2nc(cc(OC)n2)OC)c3C([O-])=O InChI=1/C18H16N4O8.Na/c1-26-12-7-11(23)19-17(20-12)29-9-5-4-6-10(15(9)16(24)25)30-18-21-13(27-2)8-14(22-18)28-3;/h4-8H,1-3H3,(H,24,25)(H,19,20,23);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Bispyribac-sodium 125401-92-5 single chemical entity Component is a metabolite of the substance benzoic acid, 2-[(4,6-dimethoxy-2-pyrimidinyl)oxy]-6-[(4-hydroxy-6-methoxy-2-pyrimidinyl)oxy],sodium salt sodium 2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-[(4-hydroxy-6-methoxypyrimidin-2-yl)oxy]benzoate Not in list C18H15N4NaO8 [Na+].Oc1nc(nc(OC)c1)Oc3cccc(Oc2nc(cc(OC)n2)OC)c3C([O-])=O InChI=1/C18H16N4O8.Na/c1-26-12-7-11(23)19-17(20-12)29-9-5-4-6-10(15(9)16(24)25)30-18-21-13(27-2)8-14(22-18)28-3;/h4-8H,1-3H3,(H,24,25)(H,19,20,23);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Italy Bispyribac-Sodium 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium) 25Oct2010 2010 doi:10.2903/j.efsa.2010.1692
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is a metabolite of the substance 6,6’-difluoro-2,2’-dibenzothiazole 6,6'-difluoro-2,2'-bibenzo[d]thiazole Not in list C14H6F2N2S2 Fc1ccc2nc(sc2c1)c3nc4ccc(F)cc4s3 InChI=1S/C14H6F2N2S2/c15-7-1-3-9-11(5-7)19-13(17-9)14-18-10-4-2-8(16)6-12(10)20-14/h1-6H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Positive RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Clethodim 99129-21-2 single chemical entity Component is identical to the substance Clethodim 99129-21-2 2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethylsulfanyl)propyl]-3-hydroxycyclohex-2-en-1-one Clethodim C17H26ClNO3S CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)SCC)CC1=O InChI=1S/C17H26ClNO3S/c1-4-14(19-22-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)23-5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The Netherlands Clethodim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is identical to the substance Clethodim 99129-21-2 2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethylsulfanyl)propyl]-3-hydroxycyclohex-2-en-1-one Clethodim C17H26ClNO3S CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)SCC)CC1=O InChI=1S/C17H26ClNO3S/c1-4-14(19-22-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)23-5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The Netherlands Clethodim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is identical to the substance Clethodim 99129-21-2 2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethylsulfanyl)propyl]-3-hydroxycyclohex-2-en-1-one Clethodim C17H26ClNO3S CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)SCC)CC1=O InChI=1S/C17H26ClNO3S/c1-4-14(19-22-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)23-5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The Netherlands Clethodim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is identical to the substance Clethodim 99129-21-2 2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethylsulfanyl)propyl]-3-hydroxycyclohex-2-en-1-one Clethodim C17H26ClNO3S CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)SCC)CC1=O InChI=1S/C17H26ClNO3S/c1-4-14(19-22-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)23-5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The Netherlands Clethodim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is identical to the substance Clethodim 99129-21-2 2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethylsulfanyl)propyl]-3-hydroxycyclohex-2-en-1-one Clethodim C17H26ClNO3S CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)SCC)CC1=O InChI=1S/C17H26ClNO3S/c1-4-14(19-22-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)23-5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The Netherlands Clethodim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is identical to the substance Clethodim 99129-21-2 2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethylsulfanyl)propyl]-3-hydroxycyclohex-2-en-1-one Clethodim C17H26ClNO3S CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)SCC)CC1=O InChI=1S/C17H26ClNO3S/c1-4-14(19-22-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)23-5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The Netherlands Clethodim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is identical to the substance Clethodim 99129-21-2 2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethylsulfanyl)propyl]-3-hydroxycyclohex-2-en-1-one Clethodim C17H26ClNO3S CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)SCC)CC1=O InChI=1S/C17H26ClNO3S/c1-4-14(19-22-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)23-5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The Netherlands Clethodim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is identical to the substance Clethodim 99129-21-2 2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethylsulfanyl)propyl]-3-hydroxycyclohex-2-en-1-one Clethodim C17H26ClNO3S CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)SCC)CC1=O InChI=1S/C17H26ClNO3S/c1-4-14(19-22-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)23-5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The Netherlands Clethodim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is identical to the substance Clethodim 99129-21-2 2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethylsulfanyl)propyl]-3-hydroxycyclohex-2-en-1-one Clethodim C17H26ClNO3S CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)SCC)CC1=O InChI=1S/C17H26ClNO3S/c1-4-14(19-22-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)23-5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Positive RMS: The Netherlands Clethodim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is identical to the substance Clethodim 99129-21-2 2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethylsulfanyl)propyl]-3-hydroxycyclohex-2-en-1-one Clethodim C17H26ClNO3S CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)SCC)CC1=O InChI=1S/C17H26ClNO3S/c1-4-14(19-22-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)23-5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: The Netherlands Clethodim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is identical to the substance Clethodim 99129-21-2 2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethylsulfanyl)propyl]-3-hydroxycyclohex-2-en-1-one Clethodim C17H26ClNO3S CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)SCC)CC1=O InChI=1S/C17H26ClNO3S/c1-4-14(19-22-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)23-5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The Netherlands Clethodim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is identical to the substance Clethodim 99129-21-2 2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethylsulfanyl)propyl]-3-hydroxycyclohex-2-en-1-one Clethodim C17H26ClNO3S CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)SCC)CC1=O InChI=1S/C17H26ClNO3S/c1-4-14(19-22-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)23-5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The Netherlands Clethodim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is identical to the substance Clethodim 99129-21-2 2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethylsulfanyl)propyl]-3-hydroxycyclohex-2-en-1-one Clethodim C17H26ClNO3S CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)SCC)CC1=O InChI=1S/C17H26ClNO3S/c1-4-14(19-22-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)23-5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The Netherlands Clethodim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is identical to the substance Clethodim 99129-21-2 2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethylsulfanyl)propyl]-3-hydroxycyclohex-2-en-1-one Clethodim C17H26ClNO3S CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)SCC)CC1=O InChI=1S/C17H26ClNO3S/c1-4-14(19-22-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)23-5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The Netherlands Clethodim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is identical to the substance Clethodim 99129-21-2 2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethylsulfanyl)propyl]-3-hydroxycyclohex-2-en-1-one Clethodim C17H26ClNO3S CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)SCC)CC1=O InChI=1S/C17H26ClNO3S/c1-4-14(19-22-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)23-5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The Netherlands Clethodim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is identical to the substance Clethodim 99129-21-2 2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethylsulfanyl)propyl]-3-hydroxycyclohex-2-en-1-one Clethodim C17H26ClNO3S CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)SCC)CC1=O InChI=1S/C17H26ClNO3S/c1-4-14(19-22-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)23-5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: The Netherlands Clethodim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is identical to the substance Clethodim 99129-21-2 2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethylsulfanyl)propyl]-3-hydroxycyclohex-2-en-1-one Clethodim C17H26ClNO3S CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)SCC)CC1=O InChI=1S/C17H26ClNO3S/c1-4-14(19-22-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)23-5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The Netherlands Clethodim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is identical to the substance Clethodim 99129-21-2 2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethylsulfanyl)propyl]-3-hydroxycyclohex-2-en-1-one Clethodim C17H26ClNO3S CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)SCC)CC1=O InChI=1S/C17H26ClNO3S/c1-4-14(19-22-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)23-5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The Netherlands Clethodim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is identical to the substance Clethodim 99129-21-2 2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethylsulfanyl)propyl]-3-hydroxycyclohex-2-en-1-one Clethodim C17H26ClNO3S CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)SCC)CC1=O InChI=1S/C17H26ClNO3S/c1-4-14(19-22-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)23-5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+ organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: The Netherlands Clethodim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is identical to the substance Clethodim 99129-21-2 2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethylsulfanyl)propyl]-3-hydroxycyclohex-2-en-1-one Clethodim C17H26ClNO3S CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)SCC)CC1=O InChI=1S/C17H26ClNO3S/c1-4-14(19-22-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)23-5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+ organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: The Netherlands Clethodim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is identical to the substance Clethodim 99129-21-2 2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethylsulfanyl)propyl]-3-hydroxycyclohex-2-en-1-one Clethodim C17H26ClNO3S CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)SCC)CC1=O InChI=1S/C17H26ClNO3S/c1-4-14(19-22-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)23-5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+ organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes without Positive RMS: The Netherlands Clethodim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is identical to the substance Clethodim 99129-21-2 2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethylsulfanyl)propyl]-3-hydroxycyclohex-2-en-1-one Clethodim C17H26ClNO3S CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)SCC)CC1=O InChI=1S/C17H26ClNO3S/c1-4-14(19-22-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)23-5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+ organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: The Netherlands Clethodim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is identical to the substance Clethodim 99129-21-2 2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethylsulfanyl)propyl]-3-hydroxycyclohex-2-en-1-one Clethodim C17H26ClNO3S CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)SCC)CC1=O InChI=1S/C17H26ClNO3S/c1-4-14(19-22-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)23-5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+ organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: The Netherlands Clethodim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is identical to the substance Clethodim 99129-21-2 2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethylsulfanyl)propyl]-3-hydroxycyclohex-2-en-1-one Clethodim C17H26ClNO3S CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)SCC)CC1=O InChI=1S/C17H26ClNO3S/c1-4-14(19-22-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)23-5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+ organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: The Netherlands Clethodim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is identical to the substance Clethodim 99129-21-2 2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethylsulfanyl)propyl]-3-hydroxycyclohex-2-en-1-one Clethodim C17H26ClNO3S CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)SCC)CC1=O InChI=1S/C17H26ClNO3S/c1-4-14(19-22-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)23-5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+ organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Sprague-Dawley 10 Male/Female oral: gavage 24.0000000000 h yes not applicable Negative RMS: The Netherlands Clethodim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is identical to the substance Clethodim 99129-21-2 2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethylsulfanyl)propyl]-3-hydroxycyclohex-2-en-1-one Clethodim C17H26ClNO3S CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)SCC)CC1=O InChI=1S/C17H26ClNO3S/c1-4-14(19-22-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)23-5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+ organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Sprague-Dawley 10 Male/Female oral: gavage 12.0000000000 h yes not applicable Negative RMS: The Netherlands Clethodim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is identical to the substance Clethodim 99129-21-2 2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethylsulfanyl)propyl]-3-hydroxycyclohex-2-en-1-one Clethodim C17H26ClNO3S CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)SCC)CC1=O InChI=1S/C17H26ClNO3S/c1-4-14(19-22-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)23-5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+ organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Sprague-Dawley 10 Male/Female oral: gavage 48.0000000000 h yes not applicable Negative RMS: The Netherlands Clethodim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is identical to the substance Clethodim 99129-21-2 2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethylsulfanyl)propyl]-3-hydroxycyclohex-2-en-1-one Clethodim C17H26ClNO3S CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)SCC)CC1=O InChI=1S/C17H26ClNO3S/c1-4-14(19-22-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)23-5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+ organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable House mouse (as animal) B6C3F1 3 Male Not reported 2.0000000000 h yes not applicable Negative RMS: The Netherlands Clethodim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is identical to the substance Clethodim 99129-21-2 2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethylsulfanyl)propyl]-3-hydroxycyclohex-2-en-1-one Clethodim C17H26ClNO3S CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)SCC)CC1=O InChI=1S/C17H26ClNO3S/c1-4-14(19-22-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)23-5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+ organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable House mouse (as animal) B6C3F1 3 Male Not reported 16.0000000000 h yes not applicable Negative RMS: The Netherlands Clethodim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxy-2-(1-iminopropan-1-yl)cyclohex-2-en-1-one 5-[2-(ethylsulfonyl)propyl]-3-hydroxy-2-propanimidoylcyclohex-2-en-1-one Clethodim-Imin-Sulfon C14H23NO4S CCC(=N)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O InChI=1/C14H23NO4S/c1-4-11(15)14-12(16)7-10(8-13(14)17)6-9(3)20(18,19)5-2/h9-10,15-16H,4-8H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The Netherlands Clethodim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxy-2-(1-iminopropan-1-yl)cyclohex-2-en-1-one 5-[2-(ethylsulfonyl)propyl]-3-hydroxy-2-propanimidoylcyclohex-2-en-1-one Clethodim-Imin-Sulfon C14H23NO4S CCC(=N)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O InChI=1/C14H23NO4S/c1-4-11(15)14-12(16)7-10(8-13(14)17)6-9(3)20(18,19)5-2/h9-10,15-16H,4-8H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The Netherlands Clethodim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxy-2-(1-iminopropan-1-yl)cyclohex-2-en-1-one 5-[2-(ethylsulfonyl)propyl]-3-hydroxy-2-propanimidoylcyclohex-2-en-1-one Clethodim-Imin-Sulfon C14H23NO4S CCC(=N)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O InChI=1/C14H23NO4S/c1-4-11(15)14-12(16)7-10(8-13(14)17)6-9(3)20(18,19)5-2/h9-10,15-16H,4-8H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The Netherlands Clethodim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxy-2-(1-iminopropan-1-yl)cyclohex-2-en-1-one 5-[2-(ethylsulfonyl)propyl]-3-hydroxy-2-propanimidoylcyclohex-2-en-1-one Clethodim-Imin-Sulfon C14H23NO4S CCC(=N)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O InChI=1/C14H23NO4S/c1-4-11(15)14-12(16)7-10(8-13(14)17)6-9(3)20(18,19)5-2/h9-10,15-16H,4-8H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The Netherlands Clethodim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxy-2-(1-iminopropan-1-yl)cyclohex-2-en-1-one 5-[2-(ethylsulfonyl)propyl]-3-hydroxy-2-propanimidoylcyclohex-2-en-1-one Clethodim-Imin-Sulfon C14H23NO4S CCC(=N)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O InChI=1/C14H23NO4S/c1-4-11(15)14-12(16)7-10(8-13(14)17)6-9(3)20(18,19)5-2/h9-10,15-16H,4-8H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The Netherlands Clethodim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxy-2-(1-iminopropan-1-yl)cyclohex-2-en-1-one 5-[2-(ethylsulfonyl)propyl]-3-hydroxy-2-propanimidoylcyclohex-2-en-1-one Clethodim-Imin-Sulfon C14H23NO4S CCC(=N)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O InChI=1/C14H23NO4S/c1-4-11(15)14-12(16)7-10(8-13(14)17)6-9(3)20(18,19)5-2/h9-10,15-16H,4-8H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The Netherlands Clethodim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxy-2-(1-iminopropan-1-yl)cyclohex-2-en-1-one 5-[2-(ethylsulfonyl)propyl]-3-hydroxy-2-propanimidoylcyclohex-2-en-1-one Clethodim-Imin-Sulfon C14H23NO4S CCC(=N)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O InChI=1/C14H23NO4S/c1-4-11(15)14-12(16)7-10(8-13(14)17)6-9(3)20(18,19)5-2/h9-10,15-16H,4-8H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: The Netherlands Clethodim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxy-2-(1-iminopropan-1-yl)cyclohex-2-en-1-one 5-[2-(ethylsulfonyl)propyl]-3-hydroxy-2-propanimidoylcyclohex-2-en-1-one Clethodim-Imin-Sulfon C14H23NO4S CCC(=N)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O InChI=1/C14H23NO4S/c1-4-11(15)14-12(16)7-10(8-13(14)17)6-9(3)20(18,19)5-2/h9-10,15-16H,4-8H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The Netherlands Clethodim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxy-2-(1-iminopropan-1-yl)cyclohex-2-en-1-one 5-[2-(ethylsulfonyl)propyl]-3-hydroxy-2-propanimidoylcyclohex-2-en-1-one Clethodim-Imin-Sulfon C14H23NO4S CCC(=N)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O InChI=1/C14H23NO4S/c1-4-11(15)14-12(16)7-10(8-13(14)17)6-9(3)20(18,19)5-2/h9-10,15-16H,4-8H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: The Netherlands Clethodim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxy-2-(1-iminopropan-1-yl)cyclohex-2-en-1-one 5-[2-(ethylsulfonyl)propyl]-3-hydroxy-2-propanimidoylcyclohex-2-en-1-one Clethodim-Imin-Sulfon C14H23NO4S CCC(=N)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O InChI=1/C14H23NO4S/c1-4-11(15)14-12(16)7-10(8-13(14)17)6-9(3)20(18,19)5-2/h9-10,15-16H,4-8H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The Netherlands Clethodim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxy-2-(1-iminopropan-1-yl)cyclohex-2-en-1-one 5-[2-(ethylsulfonyl)propyl]-3-hydroxy-2-propanimidoylcyclohex-2-en-1-one Clethodim-Imin-Sulfon C14H23NO4S CCC(=N)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O InChI=1/C14H23NO4S/c1-4-11(15)14-12(16)7-10(8-13(14)17)6-9(3)20(18,19)5-2/h9-10,15-16H,4-8H2,1-3H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: The Netherlands Clethodim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxy-2-(1-iminopropan-1-yl)cyclohex-2-en-1-one 5-[2-(ethylsulfonyl)propyl]-3-hydroxy-2-propanimidoylcyclohex-2-en-1-one Clethodim-Imin-Sulfon C14H23NO4S CCC(=N)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O InChI=1/C14H23NO4S/c1-4-11(15)14-12(16)7-10(8-13(14)17)6-9(3)20(18,19)5-2/h9-10,15-16H,4-8H2,1-3H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: The Netherlands Clethodim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3,5-dihydroxycyclohex-2-en-1-one 2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3,5-dihydroxycyclohex-2-en-1-one Clethodim, 5-Hydroxy-Sulfon C17H26ClNO6S OC1(CC(C)S(=O)(=O)CC)CC(O)=C(C(=O)C1)C(\CC)=N\OC\C=C\Cl InChI=1S/C17H26ClNO6S/c1-4-13(19-25-8-6-7-18)16-14(20)10-17(22,11-15(16)21)9-12(3)26(23,24)5-2/h6-7,12,20,22H,4-5,8-11H2,1-3H3/b7-6+,19-13+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The Netherlands Clethodim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3,5-dihydroxycyclohex-2-en-1-one 2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3,5-dihydroxycyclohex-2-en-1-one Clethodim, 5-Hydroxy-Sulfon C17H26ClNO6S OC1(CC(C)S(=O)(=O)CC)CC(O)=C(C(=O)C1)C(\CC)=N\OC\C=C\Cl InChI=1S/C17H26ClNO6S/c1-4-13(19-25-8-6-7-18)16-14(20)10-17(22,11-15(16)21)9-12(3)26(23,24)5-2/h6-7,12,20,22H,4-5,8-11H2,1-3H3/b7-6+,19-13+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The Netherlands Clethodim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3,5-dihydroxycyclohex-2-en-1-one 2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3,5-dihydroxycyclohex-2-en-1-one Clethodim, 5-Hydroxy-Sulfon C17H26ClNO6S OC1(CC(C)S(=O)(=O)CC)CC(O)=C(C(=O)C1)C(\CC)=N\OC\C=C\Cl InChI=1S/C17H26ClNO6S/c1-4-13(19-25-8-6-7-18)16-14(20)10-17(22,11-15(16)21)9-12(3)26(23,24)5-2/h6-7,12,20,22H,4-5,8-11H2,1-3H3/b7-6+,19-13+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The Netherlands Clethodim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3,5-dihydroxycyclohex-2-en-1-one 2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3,5-dihydroxycyclohex-2-en-1-one Clethodim, 5-Hydroxy-Sulfon C17H26ClNO6S OC1(CC(C)S(=O)(=O)CC)CC(O)=C(C(=O)C1)C(\CC)=N\OC\C=C\Cl InChI=1S/C17H26ClNO6S/c1-4-13(19-25-8-6-7-18)16-14(20)10-17(22,11-15(16)21)9-12(3)26(23,24)5-2/h6-7,12,20,22H,4-5,8-11H2,1-3H3/b7-6+,19-13+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The Netherlands Clethodim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3,5-dihydroxycyclohex-2-en-1-one 2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3,5-dihydroxycyclohex-2-en-1-one Clethodim, 5-Hydroxy-Sulfon C17H26ClNO6S OC1(CC(C)S(=O)(=O)CC)CC(O)=C(C(=O)C1)C(\CC)=N\OC\C=C\Cl InChI=1S/C17H26ClNO6S/c1-4-13(19-25-8-6-7-18)16-14(20)10-17(22,11-15(16)21)9-12(3)26(23,24)5-2/h6-7,12,20,22H,4-5,8-11H2,1-3H3/b7-6+,19-13+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The Netherlands Clethodim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3,5-dihydroxycyclohex-2-en-1-one 2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3,5-dihydroxycyclohex-2-en-1-one Clethodim, 5-Hydroxy-Sulfon C17H26ClNO6S OC1(CC(C)S(=O)(=O)CC)CC(O)=C(C(=O)C1)C(\CC)=N\OC\C=C\Cl InChI=1S/C17H26ClNO6S/c1-4-13(19-25-8-6-7-18)16-14(20)10-17(22,11-15(16)21)9-12(3)26(23,24)5-2/h6-7,12,20,22H,4-5,8-11H2,1-3H3/b7-6+,19-13+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The Netherlands Clethodim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3,5-dihydroxycyclohex-2-en-1-one 2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3,5-dihydroxycyclohex-2-en-1-one Clethodim, 5-Hydroxy-Sulfon C17H26ClNO6S OC1(CC(C)S(=O)(=O)CC)CC(O)=C(C(=O)C1)C(\CC)=N\OC\C=C\Cl InChI=1S/C17H26ClNO6S/c1-4-13(19-25-8-6-7-18)16-14(20)10-17(22,11-15(16)21)9-12(3)26(23,24)5-2/h6-7,12,20,22H,4-5,8-11H2,1-3H3/b7-6+,19-13+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: The Netherlands Clethodim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3,5-dihydroxycyclohex-2-en-1-one 2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3,5-dihydroxycyclohex-2-en-1-one Clethodim, 5-Hydroxy-Sulfon C17H26ClNO6S OC1(CC(C)S(=O)(=O)CC)CC(O)=C(C(=O)C1)C(\CC)=N\OC\C=C\Cl InChI=1S/C17H26ClNO6S/c1-4-13(19-25-8-6-7-18)16-14(20)10-17(22,11-15(16)21)9-12(3)26(23,24)5-2/h6-7,12,20,22H,4-5,8-11H2,1-3H3/b7-6+,19-13+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: The Netherlands Clethodim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3,5-dihydroxycyclohex-2-en-1-one 2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3,5-dihydroxycyclohex-2-en-1-one Clethodim, 5-Hydroxy-Sulfon C17H26ClNO6S OC1(CC(C)S(=O)(=O)CC)CC(O)=C(C(=O)C1)C(\CC)=N\OC\C=C\Cl InChI=1S/C17H26ClNO6S/c1-4-13(19-25-8-6-7-18)16-14(20)10-17(22,11-15(16)21)9-12(3)26(23,24)5-2/h6-7,12,20,22H,4-5,8-11H2,1-3H3/b7-6+,19-13+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The Netherlands Clethodim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3,5-dihydroxycyclohex-2-en-1-one 2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3,5-dihydroxycyclohex-2-en-1-one Clethodim, 5-Hydroxy-Sulfon C17H26ClNO6S OC1(CC(C)S(=O)(=O)CC)CC(O)=C(C(=O)C1)C(\CC)=N\OC\C=C\Cl InChI=1S/C17H26ClNO6S/c1-4-13(19-25-8-6-7-18)16-14(20)10-17(22,11-15(16)21)9-12(3)26(23,24)5-2/h6-7,12,20,22H,4-5,8-11H2,1-3H3/b7-6+,19-13+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The Netherlands Clethodim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3,5-dihydroxycyclohex-2-en-1-one 2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3,5-dihydroxycyclohex-2-en-1-one Clethodim, 5-Hydroxy-Sulfon C17H26ClNO6S OC1(CC(C)S(=O)(=O)CC)CC(O)=C(C(=O)C1)C(\CC)=N\OC\C=C\Cl InChI=1S/C17H26ClNO6S/c1-4-13(19-25-8-6-7-18)16-14(20)10-17(22,11-15(16)21)9-12(3)26(23,24)5-2/h6-7,12,20,22H,4-5,8-11H2,1-3H3/b7-6+,19-13+ organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: The Netherlands Clethodim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3,5-dihydroxycyclohex-2-en-1-one 2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3,5-dihydroxycyclohex-2-en-1-one Clethodim, 5-Hydroxy-Sulfon C17H26ClNO6S OC1(CC(C)S(=O)(=O)CC)CC(O)=C(C(=O)C1)C(\CC)=N\OC\C=C\Cl InChI=1S/C17H26ClNO6S/c1-4-13(19-25-8-6-7-18)16-14(20)10-17(22,11-15(16)21)9-12(3)26(23,24)5-2/h6-7,12,20,22H,4-5,8-11H2,1-3H3/b7-6+,19-13+ organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: The Netherlands Clethodim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one 2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one Clethodim-Sulfon C17H26ClNO5S CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O InChI=1S/C17H26ClNO5S/c1-4-14(19-24-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)25(22,23)5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Clethodim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one 2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one Clethodim-Sulfon C17H26ClNO5S CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O InChI=1S/C17H26ClNO5S/c1-4-14(19-24-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)25(22,23)5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Clethodim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one 2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one Clethodim-Sulfon C17H26ClNO5S CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O InChI=1S/C17H26ClNO5S/c1-4-14(19-24-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)25(22,23)5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Clethodim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one 2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one Clethodim-Sulfon C17H26ClNO5S CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O InChI=1S/C17H26ClNO5S/c1-4-14(19-24-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)25(22,23)5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Clethodim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one 2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one Clethodim-Sulfon C17H26ClNO5S CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O InChI=1S/C17H26ClNO5S/c1-4-14(19-24-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)25(22,23)5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+ organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Clethodim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one 2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one Clethodim-Sulfon C17H26ClNO5S CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O InChI=1S/C17H26ClNO5S/c1-4-14(19-24-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)25(22,23)5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+ organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Clethodim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one 2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one Clethodim-Sulfon C17H26ClNO5S CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O InChI=1S/C17H26ClNO5S/c1-4-14(19-24-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)25(22,23)5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+ organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Positive no information RMS: The Netherlands Clethodim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one 2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one Clethodim-Sulfon C17H26ClNO5S CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O InChI=1S/C17H26ClNO5S/c1-4-14(19-24-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)25(22,23)5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+ organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: The Netherlands Clethodim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one 2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one Clethodim-Sulfon C17H26ClNO5S CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O InChI=1S/C17H26ClNO5S/c1-4-14(19-24-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)25(22,23)5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+ organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: The Netherlands Clethodim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one 2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one Clethodim-Sulfon C17H26ClNO5S CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O InChI=1S/C17H26ClNO5S/c1-4-14(19-24-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)25(22,23)5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+ organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: The Netherlands Clethodim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 2-ethyl-6-[(2RS)-2-(ethylsulfonyl)propyl]-6,7-dihydro-1,3-benzoxazol-4(5H)-one 2-ethyl-6-[2-(ethylsulfonyl)propyl]-6,7-dihydro-1,3-benzoxazol-4(5H)-one Not in list C14H21NO4S CCS(=O)(=O)C(C)CC2Cc1oc(nc1C(=O)C2)CC InChI=1/C14H21NO4S/c1-4-13-15-14-11(16)7-10(8-12(14)19-13)6-9(3)20(17,18)5-2/h9-10H,4-8H2,1-3H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Inconclusive no information RMS: The Netherlands Clethodim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 2-ethyl-6-[(2RS)-2-(ethylsulfonyl)propyl]-6,7-dihydro-1,3-benzoxazol-4(5H)-one 2-ethyl-6-[2-(ethylsulfonyl)propyl]-6,7-dihydro-1,3-benzoxazol-4(5H)-one Not in list C14H21NO4S CCS(=O)(=O)C(C)CC2Cc1oc(nc1C(=O)C2)CC InChI=1/C14H21NO4S/c1-4-13-15-14-11(16)7-10(8-12(14)19-13)6-9(3)20(17,18)5-2/h9-10H,4-8H2,1-3H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: The Netherlands Clethodim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one 2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one Clethodim-Sulfon C17H26ClNO5S CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O InChI=1S/C17H26ClNO5S/c1-4-14(19-24-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)25(22,23)5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: The Netherlands Clethodim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one 2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one Clethodim-Sulfon C17H26ClNO5S CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O InChI=1S/C17H26ClNO5S/c1-4-14(19-24-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)25(22,23)5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Positive RMS: The Netherlands Clethodim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one 2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one Clethodim-Sulfon C17H26ClNO5S CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O InChI=1S/C17H26ClNO5S/c1-4-14(19-24-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)25(22,23)5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: The Netherlands Clethodim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one 2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one Clethodim-Sulfon C17H26ClNO5S CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O InChI=1S/C17H26ClNO5S/c1-4-14(19-24-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)25(22,23)5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: The Netherlands Clethodim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one 2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one Clethodim-Sulfon C17H26ClNO5S CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O InChI=1S/C17H26ClNO5S/c1-4-14(19-24-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)25(22,23)5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Positive RMS: The Netherlands Clethodim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one 2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one Clethodim-Sulfon C17H26ClNO5S CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O InChI=1S/C17H26ClNO5S/c1-4-14(19-24-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)25(22,23)5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: The Netherlands Clethodim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one 2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one Clethodim-Sulfon C17H26ClNO5S CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O InChI=1S/C17H26ClNO5S/c1-4-14(19-24-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)25(22,23)5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: The Netherlands Clethodim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one 2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one Clethodim-Sulfon C17H26ClNO5S CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O InChI=1S/C17H26ClNO5S/c1-4-14(19-24-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)25(22,23)5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: The Netherlands Clethodim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one 2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one Clethodim-Sulfon C17H26ClNO5S CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O InChI=1S/C17H26ClNO5S/c1-4-14(19-24-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)25(22,23)5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: The Netherlands Clethodim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one 2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one Clethodim-Sulfon C17H26ClNO5S CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O InChI=1S/C17H26ClNO5S/c1-4-14(19-24-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)25(22,23)5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: The Netherlands Clethodim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one 2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one Clethodim-Sulfon C17H26ClNO5S CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O InChI=1S/C17H26ClNO5S/c1-4-14(19-24-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)25(22,23)5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+ organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No data Acceptable Hamster (as animal) CHO Not reported no data without Negative RMS: The Netherlands Clethodim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one 2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one Clethodim-Sulfon C17H26ClNO5S CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O InChI=1S/C17H26ClNO5S/c1-4-14(19-24-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)25(22,23)5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+ organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No data Acceptable Hamster (as animal) CHO Not reported no data with Positive RMS: The Netherlands Clethodim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one 2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one Clethodim-Sulfon C17H26ClNO5S CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O InChI=1S/C17H26ClNO5S/c1-4-14(19-24-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)25(22,23)5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+ organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable House mouse (as animal) CD-1 6 Male Not reported no data not applicable Inconclusive no evidence RMS: The Netherlands Clethodim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one 2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one Clethodim-Sulfon C17H26ClNO5S CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O InChI=1S/C17H26ClNO5S/c1-4-14(19-24-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)25(22,23)5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+ organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo Equivalent or similar to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No data Acceptable House mouse (as animal) ICR 6 Male Not reported no data not applicable Negative RMS: The Netherlands Clethodim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 2-ethyl-6-[(2RS)-2-(ethylsulfonyl)propyl]-6,7-dihydro-1,3-benzoxazol-4(5H)-one 2-ethyl-6-[2-(ethylsulfonyl)propyl]-6,7-dihydro-1,3-benzoxazol-4(5H)-one Not in list C14H21NO4S CCS(=O)(=O)C(C)CC2Cc1oc(nc1C(=O)C2)CC InChI=1/C14H21NO4S/c1-4-13-15-14-11(16)7-10(8-12(14)19-13)6-9(3)20(17,18)5-2/h9-10H,4-8H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: The Netherlands Clethodim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 2-ethyl-6-[(2RS)-2-(ethylsulfonyl)propyl]-6,7-dihydro-1,3-benzoxazol-4(5H)-one 2-ethyl-6-[2-(ethylsulfonyl)propyl]-6,7-dihydro-1,3-benzoxazol-4(5H)-one Not in list C14H21NO4S CCS(=O)(=O)C(C)CC2Cc1oc(nc1C(=O)C2)CC InChI=1/C14H21NO4S/c1-4-13-15-14-11(16)7-10(8-12(14)19-13)6-9(3)20(17,18)5-2/h9-10H,4-8H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: The Netherlands Clethodim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 2-ethyl-6-[(2RS)-2-(ethylsulfonyl)propyl]-6,7-dihydro-1,3-benzoxazol-4(5H)-one 2-ethyl-6-[2-(ethylsulfonyl)propyl]-6,7-dihydro-1,3-benzoxazol-4(5H)-one Not in list C14H21NO4S CCS(=O)(=O)C(C)CC2Cc1oc(nc1C(=O)C2)CC InChI=1/C14H21NO4S/c1-4-13-15-14-11(16)7-10(8-12(14)19-13)6-9(3)20(17,18)5-2/h9-10H,4-8H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: The Netherlands Clethodim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 2-ethyl-6-[(2RS)-2-(ethylsulfonyl)propyl]-6,7-dihydro-1,3-benzoxazol-4(5H)-one 2-ethyl-6-[2-(ethylsulfonyl)propyl]-6,7-dihydro-1,3-benzoxazol-4(5H)-one Not in list C14H21NO4S CCS(=O)(=O)C(C)CC2Cc1oc(nc1C(=O)C2)CC InChI=1/C14H21NO4S/c1-4-13-15-14-11(16)7-10(8-12(14)19-13)6-9(3)20(17,18)5-2/h9-10H,4-8H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: The Netherlands Clethodim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 2-ethyl-6-[(2RS)-2-(ethylsulfonyl)propyl]-6,7-dihydro-1,3-benzoxazol-4(5H)-one 2-ethyl-6-[2-(ethylsulfonyl)propyl]-6,7-dihydro-1,3-benzoxazol-4(5H)-one Not in list C14H21NO4S CCS(=O)(=O)C(C)CC2Cc1oc(nc1C(=O)C2)CC InChI=1/C14H21NO4S/c1-4-13-15-14-11(16)7-10(8-12(14)19-13)6-9(3)20(17,18)5-2/h9-10H,4-8H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: The Netherlands Clethodim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 2-ethyl-6-[(2RS)-2-(ethylsulfonyl)propyl]-6,7-dihydro-1,3-benzoxazol-4(5H)-one 2-ethyl-6-[2-(ethylsulfonyl)propyl]-6,7-dihydro-1,3-benzoxazol-4(5H)-one Not in list C14H21NO4S CCS(=O)(=O)C(C)CC2Cc1oc(nc1C(=O)C2)CC InChI=1/C14H21NO4S/c1-4-13-15-14-11(16)7-10(8-12(14)19-13)6-9(3)20(17,18)5-2/h9-10H,4-8H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: The Netherlands Clethodim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 2-ethyl-6-[(2RS)-2-(ethylsulfonyl)propyl]-6,7-dihydro-1,3-benzoxazol-4(5H)-one 2-ethyl-6-[2-(ethylsulfonyl)propyl]-6,7-dihydro-1,3-benzoxazol-4(5H)-one Not in list C14H21NO4S CCS(=O)(=O)C(C)CC2Cc1oc(nc1C(=O)C2)CC InChI=1/C14H21NO4S/c1-4-13-15-14-11(16)7-10(8-12(14)19-13)6-9(3)20(17,18)5-2/h9-10H,4-8H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: The Netherlands Clethodim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 2-ethyl-6-[(2RS)-2-(ethylsulfonyl)propyl]-6,7-dihydro-1,3-benzoxazol-4(5H)-one 2-ethyl-6-[2-(ethylsulfonyl)propyl]-6,7-dihydro-1,3-benzoxazol-4(5H)-one Not in list C14H21NO4S CCS(=O)(=O)C(C)CC2Cc1oc(nc1C(=O)C2)CC InChI=1/C14H21NO4S/c1-4-13-15-14-11(16)7-10(8-12(14)19-13)6-9(3)20(17,18)5-2/h9-10H,4-8H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: The Netherlands Clethodim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 2-ethyl-6-[(2RS)-2-(ethylsulfonyl)propyl]-6,7-dihydro-1,3-benzoxazol-4(5H)-one 2-ethyl-6-[2-(ethylsulfonyl)propyl]-6,7-dihydro-1,3-benzoxazol-4(5H)-one Not in list C14H21NO4S CCS(=O)(=O)C(C)CC2Cc1oc(nc1C(=O)C2)CC InChI=1/C14H21NO4S/c1-4-13-15-14-11(16)7-10(8-12(14)19-13)6-9(3)20(17,18)5-2/h9-10H,4-8H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: The Netherlands Clethodim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 2-ethyl-6-[(2RS)-2-(ethylsulfonyl)propyl]-6,7-dihydro-1,3-benzoxazol-4(5H)-one 2-ethyl-6-[2-(ethylsulfonyl)propyl]-6,7-dihydro-1,3-benzoxazol-4(5H)-one Not in list C14H21NO4S CCS(=O)(=O)C(C)CC2Cc1oc(nc1C(=O)C2)CC InChI=1/C14H21NO4S/c1-4-13-15-14-11(16)7-10(8-12(14)19-13)6-9(3)20(17,18)5-2/h9-10H,4-8H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: The Netherlands Clethodim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 2-ethyl-6-[(2RS)-2-(ethylsulfonyl)propyl]-6,7-dihydro-1,3-benzoxazol-4(5H)-one 2-ethyl-6-[2-(ethylsulfonyl)propyl]-6,7-dihydro-1,3-benzoxazol-4(5H)-one Not in list C14H21NO4S CCS(=O)(=O)C(C)CC2Cc1oc(nc1C(=O)C2)CC InChI=1/C14H21NO4S/c1-4-13-15-14-11(16)7-10(8-12(14)19-13)6-9(3)20(17,18)5-2/h9-10H,4-8H2,1-3H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No data Acceptable Hamster (as animal) CHO Not reported no data without Negative RMS: The Netherlands Clethodim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 2-ethyl-6-[(2RS)-2-(ethylsulfonyl)propyl]-6,7-dihydro-1,3-benzoxazol-4(5H)-one 2-ethyl-6-[2-(ethylsulfonyl)propyl]-6,7-dihydro-1,3-benzoxazol-4(5H)-one Not in list C14H21NO4S CCS(=O)(=O)C(C)CC2Cc1oc(nc1C(=O)C2)CC InChI=1/C14H21NO4S/c1-4-13-15-14-11(16)7-10(8-12(14)19-13)6-9(3)20(17,18)5-2/h9-10H,4-8H2,1-3H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No data Acceptable Hamster (as animal) CHO Not reported no data with Positive RMS: The Netherlands Clethodim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 2-ethyl-6-[(2RS)-2-(ethylsulfonyl)propyl]-6,7-dihydro-1,3-benzoxazol-4(5H)-one 2-ethyl-6-[2-(ethylsulfonyl)propyl]-6,7-dihydro-1,3-benzoxazol-4(5H)-one Not in list C14H21NO4S CCS(=O)(=O)C(C)CC2Cc1oc(nc1C(=O)C2)CC InChI=1/C14H21NO4S/c1-4-13-15-14-11(16)7-10(8-12(14)19-13)6-9(3)20(17,18)5-2/h9-10H,4-8H2,1-3H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable House mouse (as animal) CD-1 Male Not reported no data not applicable Negative no evidence RMS: The Netherlands Clethodim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is identical to the substance Ethametsulfuron methyl 97780-06-8 methyl 2-[[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoylsulfamoyl]benzoate Ethametsulfuron-Methyl C15H18N6O6S CCOC1=NC(=NC(=N1)NC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C15H18N6O6S/c1-4-27-15-19-12(16-2)17-13(20-15)18-14(23)21-28(24,25)10-8-6-5-7-9(10)11(22)26-3/h5-8H,4H2,1-3H3,(H3,16,17,18,19,20,21,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is identical to the substance Ethametsulfuron methyl 97780-06-8 methyl 2-[[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoylsulfamoyl]benzoate Ethametsulfuron-Methyl C15H18N6O6S CCOC1=NC(=NC(=N1)NC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C15H18N6O6S/c1-4-27-15-19-12(16-2)17-13(20-15)18-14(23)21-28(24,25)10-8-6-5-7-9(10)11(22)26-3/h5-8H,4H2,1-3H3,(H3,16,17,18,19,20,21,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is identical to the substance Ethametsulfuron methyl 97780-06-8 methyl 2-[[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoylsulfamoyl]benzoate Ethametsulfuron-Methyl C15H18N6O6S CCOC1=NC(=NC(=N1)NC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C15H18N6O6S/c1-4-27-15-19-12(16-2)17-13(20-15)18-14(23)21-28(24,25)10-8-6-5-7-9(10)11(22)26-3/h5-8H,4H2,1-3H3,(H3,16,17,18,19,20,21,23) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Rat (as animal) hepatocytes Not reported yes without Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is identical to the substance Ethametsulfuron methyl 97780-06-8 methyl 2-[[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoylsulfamoyl]benzoate Ethametsulfuron-Methyl C15H18N6O6S CCOC1=NC(=NC(=N1)NC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C15H18N6O6S/c1-4-27-15-19-12(16-2)17-13(20-15)18-14(23)21-28(24,25)10-8-6-5-7-9(10)11(22)26-3/h5-8H,4H2,1-3H3,(H3,16,17,18,19,20,21,23) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect-toxicokinetic investigations RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is identical to the substance Ethametsulfuron methyl 97780-06-8 methyl 2-[[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoylsulfamoyl]benzoate Ethametsulfuron-Methyl C15H18N6O6S CCOC1=NC(=NC(=N1)NC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C15H18N6O6S/c1-4-27-15-19-12(16-2)17-13(20-15)18-14(23)21-28(24,25)10-8-6-5-7-9(10)11(22)26-3/h5-8H,4H2,1-3H3,(H3,16,17,18,19,20,21,23) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect-toxicokinetic investigations RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is identical to the substance Ethametsulfuron methyl 97780-06-8 methyl 2-[[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoylsulfamoyl]benzoate Ethametsulfuron-Methyl C15H18N6O6S CCOC1=NC(=NC(=N1)NC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C15H18N6O6S/c1-4-27-15-19-12(16-2)17-13(20-15)18-14(23)21-28(24,25)10-8-6-5-7-9(10)11(22)26-3/h5-8H,4H2,1-3H3,(H3,16,17,18,19,20,21,23) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 72.0000000000 h yes, concurrent vehicle not applicable Negative indirect-toxicokinetic investigations RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is identical to the substance Ethametsulfuron methyl 97780-06-8 methyl 2-[[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoylsulfamoyl]benzoate Ethametsulfuron-Methyl C15H18N6O6S CCOC1=NC(=NC(=N1)NC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C15H18N6O6S/c1-4-27-15-19-12(16-2)17-13(20-15)18-14(23)21-28(24,25)10-8-6-5-7-9(10)11(22)26-3/h5-8H,4H2,1-3H3,(H3,16,17,18,19,20,21,23) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Crj:CD(SD) 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity$indirect-toxicokinetic investigations RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is identical to the substance Ethametsulfuron methyl 97780-06-8 methyl 2-[[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoylsulfamoyl]benzoate Ethametsulfuron-Methyl C15H18N6O6S CCOC1=NC(=NC(=N1)NC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C15H18N6O6S/c1-4-27-15-19-12(16-2)17-13(20-15)18-14(23)21-28(24,25)10-8-6-5-7-9(10)11(22)26-3/h5-8H,4H2,1-3H3,(H3,16,17,18,19,20,21,23) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Crj:CD(SD) 10 Male/Female oral: gavage 6.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity$indirect-toxicokinetic investigations RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is identical to the substance Ethametsulfuron methyl 97780-06-8 methyl 2-[[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoylsulfamoyl]benzoate Ethametsulfuron-Methyl C15H18N6O6S CCOC1=NC(=NC(=N1)NC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C15H18N6O6S/c1-4-27-15-19-12(16-2)17-13(20-15)18-14(23)21-28(24,25)10-8-6-5-7-9(10)11(22)26-3/h5-8H,4H2,1-3H3,(H3,16,17,18,19,20,21,23) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Crj:CD(SD) 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity$indirect-toxicokinetic investigations RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 1-[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]urea 1-[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]urea Not in list C7H12N6O2 CCOc1nc(nc(NC(N)=O)n1)NC InChI=1/C7H12N6O2/c1-3-15-7-12-5(9-2)11-6(13-7)10-4(8)14/h3H2,1-2H3,(H4,8,9,10,11,12,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 1-[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]urea 1-[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]urea Not in list C7H12N6O2 CCOc1nc(nc(NC(N)=O)n1)NC InChI=1/C7H12N6O2/c1-3-15-7-12-5(9-2)11-6(13-7)10-4(8)14/h3H2,1-2H3,(H4,8,9,10,11,12,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 1-[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]urea 1-[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]urea Not in list C7H12N6O2 CCOc1nc(nc(NC(N)=O)n1)NC InChI=1/C7H12N6O2/c1-3-15-7-12-5(9-2)11-6(13-7)10-4(8)14/h3H2,1-2H3,(H4,8,9,10,11,12,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 1-[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]urea 1-[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]urea Not in list C7H12N6O2 CCOc1nc(nc(NC(N)=O)n1)NC InChI=1/C7H12N6O2/c1-3-15-7-12-5(9-2)11-6(13-7)10-4(8)14/h3H2,1-2H3,(H4,8,9,10,11,12,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 1-[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]urea 1-[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]urea Not in list C7H12N6O2 CCOc1nc(nc(NC(N)=O)n1)NC InChI=1/C7H12N6O2/c1-3-15-7-12-5(9-2)11-6(13-7)10-4(8)14/h3H2,1-2H3,(H4,8,9,10,11,12,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 1-[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]urea 1-[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]urea Not in list C7H12N6O2 CCOc1nc(nc(NC(N)=O)n1)NC InChI=1/C7H12N6O2/c1-3-15-7-12-5(9-2)11-6(13-7)10-4(8)14/h3H2,1-2H3,(H4,8,9,10,11,12,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 1-[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]urea 1-[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]urea Not in list C7H12N6O2 CCOc1nc(nc(NC(N)=O)n1)NC InChI=1/C7H12N6O2/c1-3-15-7-12-5(9-2)11-6(13-7)10-4(8)14/h3H2,1-2H3,(H4,8,9,10,11,12,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 1-[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]urea 1-[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]urea Not in list C7H12N6O2 CCOc1nc(nc(NC(N)=O)n1)NC InChI=1/C7H12N6O2/c1-3-15-7-12-5(9-2)11-6(13-7)10-4(8)14/h3H2,1-2H3,(H4,8,9,10,11,12,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 1-[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]urea 1-[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]urea Not in list C7H12N6O2 CCOc1nc(nc(NC(N)=O)n1)NC InChI=1/C7H12N6O2/c1-3-15-7-12-5(9-2)11-6(13-7)10-4(8)14/h3H2,1-2H3,(H4,8,9,10,11,12,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 1-[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]urea 1-[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]urea Not in list C7H12N6O2 CCOc1nc(nc(NC(N)=O)n1)NC InChI=1/C7H12N6O2/c1-3-15-7-12-5(9-2)11-6(13-7)10-4(8)14/h3H2,1-2H3,(H4,8,9,10,11,12,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 1-[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]urea 1-[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]urea Not in list C7H12N6O2 CCOc1nc(nc(NC(N)=O)n1)NC InChI=1/C7H12N6O2/c1-3-15-7-12-5(9-2)11-6(13-7)10-4(8)14/h3H2,1-2H3,(H4,8,9,10,11,12,13,14) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 1-[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]urea 1-[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]urea Not in list C7H12N6O2 CCOc1nc(nc(NC(N)=O)n1)NC InChI=1/C7H12N6O2/c1-3-15-7-12-5(9-2)11-6(13-7)10-4(8)14/h3H2,1-2H3,(H4,8,9,10,11,12,13,14) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 1-[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]urea 1-[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]urea Not in list C7H12N6O2 CCOc1nc(nc(NC(N)=O)n1)NC InChI=1/C7H12N6O2/c1-3-15-7-12-5(9-2)11-6(13-7)10-4(8)14/h3H2,1-2H3,(H4,8,9,10,11,12,13,14) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, historical without Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 1-[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]urea 1-[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]urea Not in list C7H12N6O2 CCOc1nc(nc(NC(N)=O)n1)NC InChI=1/C7H12N6O2/c1-3-15-7-12-5(9-2)11-6(13-7)10-4(8)14/h3H2,1-2H3,(H4,8,9,10,11,12,13,14) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, historical with Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 6-ethoxy-N-methyl-1,3,5-triazine-2,4-diamine 403-580-7 62096-63-3 6-ethoxy-2-N-methyl-1,3,5-triazine-2,4-diamine Not in list C6H11N5O CCOC1=NC(=NC(=N1)NC)N InChI=1S/C6H11N5O/c1-3-12-6-10-4(7)9-5(8-2)11-6/h3H2,1-2H3,(H3,7,8,9,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 6-ethoxy-N-methyl-1,3,5-triazine-2,4-diamine 403-580-7 62096-63-3 6-ethoxy-2-N-methyl-1,3,5-triazine-2,4-diamine Not in list C6H11N5O CCOC1=NC(=NC(=N1)NC)N InChI=1S/C6H11N5O/c1-3-12-6-10-4(7)9-5(8-2)11-6/h3H2,1-2H3,(H3,7,8,9,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 6-ethoxy-N-methyl-1,3,5-triazine-2,4-diamine 403-580-7 62096-63-3 6-ethoxy-2-N-methyl-1,3,5-triazine-2,4-diamine Not in list C6H11N5O CCOC1=NC(=NC(=N1)NC)N InChI=1S/C6H11N5O/c1-3-12-6-10-4(7)9-5(8-2)11-6/h3H2,1-2H3,(H3,7,8,9,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 6-ethoxy-N-methyl-1,3,5-triazine-2,4-diamine 403-580-7 62096-63-3 6-ethoxy-2-N-methyl-1,3,5-triazine-2,4-diamine Not in list C6H11N5O CCOC1=NC(=NC(=N1)NC)N InChI=1S/C6H11N5O/c1-3-12-6-10-4(7)9-5(8-2)11-6/h3H2,1-2H3,(H3,7,8,9,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 6-ethoxy-N-methyl-1,3,5-triazine-2,4-diamine 403-580-7 62096-63-3 6-ethoxy-2-N-methyl-1,3,5-triazine-2,4-diamine Not in list C6H11N5O CCOC1=NC(=NC(=N1)NC)N InChI=1S/C6H11N5O/c1-3-12-6-10-4(7)9-5(8-2)11-6/h3H2,1-2H3,(H3,7,8,9,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 6-ethoxy-N-methyl-1,3,5-triazine-2,4-diamine 403-580-7 62096-63-3 6-ethoxy-2-N-methyl-1,3,5-triazine-2,4-diamine Not in list C6H11N5O CCOC1=NC(=NC(=N1)NC)N InChI=1S/C6H11N5O/c1-3-12-6-10-4(7)9-5(8-2)11-6/h3H2,1-2H3,(H3,7,8,9,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 6-ethoxy-N-methyl-1,3,5-triazine-2,4-diamine 403-580-7 62096-63-3 6-ethoxy-2-N-methyl-1,3,5-triazine-2,4-diamine Not in list C6H11N5O CCOC1=NC(=NC(=N1)NC)N InChI=1S/C6H11N5O/c1-3-12-6-10-4(7)9-5(8-2)11-6/h3H2,1-2H3,(H3,7,8,9,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 6-ethoxy-N-methyl-1,3,5-triazine-2,4-diamine 403-580-7 62096-63-3 6-ethoxy-2-N-methyl-1,3,5-triazine-2,4-diamine Not in list C6H11N5O CCOC1=NC(=NC(=N1)NC)N InChI=1S/C6H11N5O/c1-3-12-6-10-4(7)9-5(8-2)11-6/h3H2,1-2H3,(H3,7,8,9,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 6-ethoxy-N-methyl-1,3,5-triazine-2,4-diamine 403-580-7 62096-63-3 6-ethoxy-2-N-methyl-1,3,5-triazine-2,4-diamine Not in list C6H11N5O CCOC1=NC(=NC(=N1)NC)N InChI=1S/C6H11N5O/c1-3-12-6-10-4(7)9-5(8-2)11-6/h3H2,1-2H3,(H3,7,8,9,10,11) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 6-ethoxy-N-methyl-1,3,5-triazine-2,4-diamine 403-580-7 62096-63-3 6-ethoxy-2-N-methyl-1,3,5-triazine-2,4-diamine Not in list C6H11N5O CCOC1=NC(=NC(=N1)NC)N InChI=1S/C6H11N5O/c1-3-12-6-10-4(7)9-5(8-2)11-6/h3H2,1-2H3,(H3,7,8,9,10,11) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 2-[(4-ethoxy-6-methylamino-1,3,5-triazin-2-yl)carbamoylsulfamoyl] benzoic acid 2-({[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoic acid Not in list C14H16N6O6S CCOc2nc(nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)O)n2)NC InChI=1/C14H16N6O6S/c1-3-26-14-18-11(15-2)16-12(19-14)17-13(23)20-27(24,25)9-7-5-4-6-8(9)10(21)22/h4-7H,3H2,1-2H3,(H,21,22)(H3,15,16,17,18,19,20,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 2-[(4-ethoxy-6-methylamino-1,3,5-triazin-2-yl)carbamoylsulfamoyl] benzoic acid 2-({[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoic acid Not in list C14H16N6O6S CCOc2nc(nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)O)n2)NC InChI=1/C14H16N6O6S/c1-3-26-14-18-11(15-2)16-12(19-14)17-13(23)20-27(24,25)9-7-5-4-6-8(9)10(21)22/h4-7H,3H2,1-2H3,(H,21,22)(H3,15,16,17,18,19,20,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 2-[(4-ethoxy-6-methylamino-1,3,5-triazin-2-yl)carbamoylsulfamoyl] benzoic acid 2-({[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoic acid Not in list C14H16N6O6S CCOc2nc(nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)O)n2)NC InChI=1/C14H16N6O6S/c1-3-26-14-18-11(15-2)16-12(19-14)17-13(23)20-27(24,25)9-7-5-4-6-8(9)10(21)22/h4-7H,3H2,1-2H3,(H,21,22)(H3,15,16,17,18,19,20,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 2-[(4-ethoxy-6-methylamino-1,3,5-triazin-2-yl)carbamoylsulfamoyl] benzoic acid 2-({[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoic acid Not in list C14H16N6O6S CCOc2nc(nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)O)n2)NC InChI=1/C14H16N6O6S/c1-3-26-14-18-11(15-2)16-12(19-14)17-13(23)20-27(24,25)9-7-5-4-6-8(9)10(21)22/h4-7H,3H2,1-2H3,(H,21,22)(H3,15,16,17,18,19,20,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 2-[(4-ethoxy-6-methylamino-1,3,5-triazin-2-yl)carbamoylsulfamoyl] benzoic acid 2-({[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoic acid Not in list C14H16N6O6S CCOc2nc(nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)O)n2)NC InChI=1/C14H16N6O6S/c1-3-26-14-18-11(15-2)16-12(19-14)17-13(23)20-27(24,25)9-7-5-4-6-8(9)10(21)22/h4-7H,3H2,1-2H3,(H,21,22)(H3,15,16,17,18,19,20,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 2-[(4-ethoxy-6-methylamino-1,3,5-triazin-2-yl)carbamoylsulfamoyl] benzoic acid 2-({[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoic acid Not in list C14H16N6O6S CCOc2nc(nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)O)n2)NC InChI=1/C14H16N6O6S/c1-3-26-14-18-11(15-2)16-12(19-14)17-13(23)20-27(24,25)9-7-5-4-6-8(9)10(21)22/h4-7H,3H2,1-2H3,(H,21,22)(H3,15,16,17,18,19,20,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 2-[(4-ethoxy-6-methylamino-1,3,5-triazin-2-yl)carbamoylsulfamoyl] benzoic acid 2-({[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoic acid Not in list C14H16N6O6S CCOc2nc(nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)O)n2)NC InChI=1/C14H16N6O6S/c1-3-26-14-18-11(15-2)16-12(19-14)17-13(23)20-27(24,25)9-7-5-4-6-8(9)10(21)22/h4-7H,3H2,1-2H3,(H,21,22)(H3,15,16,17,18,19,20,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 2-[(4-ethoxy-6-methylamino-1,3,5-triazin-2-yl)carbamoylsulfamoyl] benzoic acid 2-({[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoic acid Not in list C14H16N6O6S CCOc2nc(nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)O)n2)NC InChI=1/C14H16N6O6S/c1-3-26-14-18-11(15-2)16-12(19-14)17-13(23)20-27(24,25)9-7-5-4-6-8(9)10(21)22/h4-7H,3H2,1-2H3,(H,21,22)(H3,15,16,17,18,19,20,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 2-[(4-ethoxy-6-methylamino-1,3,5-triazin-2-yl)carbamoylsulfamoyl] benzoic acid 2-({[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoic acid Not in list C14H16N6O6S CCOc2nc(nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)O)n2)NC InChI=1/C14H16N6O6S/c1-3-26-14-18-11(15-2)16-12(19-14)17-13(23)20-27(24,25)9-7-5-4-6-8(9)10(21)22/h4-7H,3H2,1-2H3,(H,21,22)(H3,15,16,17,18,19,20,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 2-[(4-ethoxy-6-methylamino-1,3,5-triazin-2-yl)carbamoylsulfamoyl] benzoic acid 2-({[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoic acid Not in list C14H16N6O6S CCOc2nc(nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)O)n2)NC InChI=1/C14H16N6O6S/c1-3-26-14-18-11(15-2)16-12(19-14)17-13(23)20-27(24,25)9-7-5-4-6-8(9)10(21)22/h4-7H,3H2,1-2H3,(H,21,22)(H3,15,16,17,18,19,20,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 2-[(4-ethoxy-6-methylamino-1,3,5-triazin-2-yl)carbamoylsulfamoyl] benzoic acid 2-({[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoic acid Not in list C14H16N6O6S CCOc2nc(nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)O)n2)NC InChI=1/C14H16N6O6S/c1-3-26-14-18-11(15-2)16-12(19-14)17-13(23)20-27(24,25)9-7-5-4-6-8(9)10(21)22/h4-7H,3H2,1-2H3,(H,21,22)(H3,15,16,17,18,19,20,23) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 2-[(4-ethoxy-6-methylamino-1,3,5-triazin-2-yl)carbamoylsulfamoyl] benzoic acid 2-({[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoic acid Not in list C14H16N6O6S CCOc2nc(nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)O)n2)NC InChI=1/C14H16N6O6S/c1-3-26-14-18-11(15-2)16-12(19-14)17-13(23)20-27(24,25)9-7-5-4-6-8(9)10(21)22/h4-7H,3H2,1-2H3,(H,21,22)(H3,15,16,17,18,19,20,23) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 2-[(4-ethoxy-6-methylamino-1,3,5-triazin-2-yl)carbamoylsulfamoyl] benzoic acid 2-({[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoic acid Not in list C14H16N6O6S CCOc2nc(nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)O)n2)NC InChI=1/C14H16N6O6S/c1-3-26-14-18-11(15-2)16-12(19-14)17-13(23)20-27(24,25)9-7-5-4-6-8(9)10(21)22/h4-7H,3H2,1-2H3,(H,21,22)(H3,15,16,17,18,19,20,23) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 2-[(4-ethoxy-6-methylamino-1,3,5-triazin-2-yl)carbamoylsulfamoyl] benzoic acid 2-({[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoic acid Not in list C14H16N6O6S CCOc2nc(nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)O)n2)NC InChI=1/C14H16N6O6S/c1-3-26-14-18-11(15-2)16-12(19-14)17-13(23)20-27(24,25)9-7-5-4-6-8(9)10(21)22/h4-7H,3H2,1-2H3,(H,21,22)(H3,15,16,17,18,19,20,23) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance methyl 2-({[4-hydroxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoate methyl 2-({[4-hydroxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoate Not in list C13H14N6O6S CNc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2 InChI=1/C13H14N6O6S/c1-14-10-15-11(17-12(21)16-10)18-13(22)19-26(23,24)8-6-4-3-5-7(8)9(20)25-2/h3-6H,1-2H3,(H4,14,15,16,17,18,19,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance methyl 2-({[4-hydroxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoate methyl 2-({[4-hydroxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoate Not in list C13H14N6O6S CNc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2 InChI=1/C13H14N6O6S/c1-14-10-15-11(17-12(21)16-10)18-13(22)19-26(23,24)8-6-4-3-5-7(8)9(20)25-2/h3-6H,1-2H3,(H4,14,15,16,17,18,19,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance methyl 2-({[4-hydroxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoate methyl 2-({[4-hydroxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoate Not in list C13H14N6O6S CNc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2 InChI=1/C13H14N6O6S/c1-14-10-15-11(17-12(21)16-10)18-13(22)19-26(23,24)8-6-4-3-5-7(8)9(20)25-2/h3-6H,1-2H3,(H4,14,15,16,17,18,19,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance methyl 2-({[4-hydroxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoate methyl 2-({[4-hydroxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoate Not in list C13H14N6O6S CNc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2 InChI=1/C13H14N6O6S/c1-14-10-15-11(17-12(21)16-10)18-13(22)19-26(23,24)8-6-4-3-5-7(8)9(20)25-2/h3-6H,1-2H3,(H4,14,15,16,17,18,19,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance methyl 2-({[4-hydroxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoate methyl 2-({[4-hydroxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoate Not in list C13H14N6O6S CNc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2 InChI=1/C13H14N6O6S/c1-14-10-15-11(17-12(21)16-10)18-13(22)19-26(23,24)8-6-4-3-5-7(8)9(20)25-2/h3-6H,1-2H3,(H4,14,15,16,17,18,19,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance methyl 2-({[4-hydroxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoate methyl 2-({[4-hydroxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoate Not in list C13H14N6O6S CNc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2 InChI=1/C13H14N6O6S/c1-14-10-15-11(17-12(21)16-10)18-13(22)19-26(23,24)8-6-4-3-5-7(8)9(20)25-2/h3-6H,1-2H3,(H4,14,15,16,17,18,19,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance methyl 2-({[4-hydroxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoate methyl 2-({[4-hydroxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoate Not in list C13H14N6O6S CNc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2 InChI=1/C13H14N6O6S/c1-14-10-15-11(17-12(21)16-10)18-13(22)19-26(23,24)8-6-4-3-5-7(8)9(20)25-2/h3-6H,1-2H3,(H4,14,15,16,17,18,19,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance methyl 2-({[4-hydroxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoate methyl 2-({[4-hydroxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoate Not in list C13H14N6O6S CNc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2 InChI=1/C13H14N6O6S/c1-14-10-15-11(17-12(21)16-10)18-13(22)19-26(23,24)8-6-4-3-5-7(8)9(20)25-2/h3-6H,1-2H3,(H4,14,15,16,17,18,19,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance methyl 2-({[4-hydroxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoate methyl 2-({[4-hydroxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoate Not in list C13H14N6O6S CNc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2 InChI=1/C13H14N6O6S/c1-14-10-15-11(17-12(21)16-10)18-13(22)19-26(23,24)8-6-4-3-5-7(8)9(20)25-2/h3-6H,1-2H3,(H4,14,15,16,17,18,19,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance methyl 2-({[4-hydroxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoate methyl 2-({[4-hydroxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoate Not in list C13H14N6O6S CNc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2 InChI=1/C13H14N6O6S/c1-14-10-15-11(17-12(21)16-10)18-13(22)19-26(23,24)8-6-4-3-5-7(8)9(20)25-2/h3-6H,1-2H3,(H4,14,15,16,17,18,19,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance methyl 2-({[4-hydroxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoate methyl 2-({[4-hydroxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoate Not in list C13H14N6O6S CNc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2 InChI=1/C13H14N6O6S/c1-14-10-15-11(17-12(21)16-10)18-13(22)19-26(23,24)8-6-4-3-5-7(8)9(20)25-2/h3-6H,1-2H3,(H4,14,15,16,17,18,19,21,22) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance methyl 2-({[4-hydroxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoate methyl 2-({[4-hydroxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoate Not in list C13H14N6O6S CNc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2 InChI=1/C13H14N6O6S/c1-14-10-15-11(17-12(21)16-10)18-13(22)19-26(23,24)8-6-4-3-5-7(8)9(20)25-2/h3-6H,1-2H3,(H4,14,15,16,17,18,19,21,22) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance methyl 2-({[4-hydroxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoate methyl 2-({[4-hydroxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoate Not in list C13H14N6O6S CNc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2 InChI=1/C13H14N6O6S/c1-14-10-15-11(17-12(21)16-10)18-13(22)19-26(23,24)8-6-4-3-5-7(8)9(20)25-2/h3-6H,1-2H3,(H4,14,15,16,17,18,19,21,22) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance methyl 2-({[4-hydroxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoate methyl 2-({[4-hydroxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoate Not in list C13H14N6O6S CNc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2 InChI=1/C13H14N6O6S/c1-14-10-15-11(17-12(21)16-10)18-13(22)19-26(23,24)8-6-4-3-5-7(8)9(20)25-2/h3-6H,1-2H3,(H4,14,15,16,17,18,19,21,22) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl] sulfamoyl}benzoate methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoate Not in list C12H12N6O6S Nc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2 InChI=1/C12H12N6O6S/c1-24-8(19)6-4-2-3-5-7(6)25(22,23)18-12(21)17-10-14-9(13)15-11(20)16-10/h2-5H,1H3,(H5,13,14,15,16,17,18,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl] sulfamoyl}benzoate methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoate Not in list C12H12N6O6S Nc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2 InChI=1/C12H12N6O6S/c1-24-8(19)6-4-2-3-5-7(6)25(22,23)18-12(21)17-10-14-9(13)15-11(20)16-10/h2-5H,1H3,(H5,13,14,15,16,17,18,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl] sulfamoyl}benzoate methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoate Not in list C12H12N6O6S Nc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2 InChI=1/C12H12N6O6S/c1-24-8(19)6-4-2-3-5-7(6)25(22,23)18-12(21)17-10-14-9(13)15-11(20)16-10/h2-5H,1H3,(H5,13,14,15,16,17,18,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl] sulfamoyl}benzoate methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoate Not in list C12H12N6O6S Nc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2 InChI=1/C12H12N6O6S/c1-24-8(19)6-4-2-3-5-7(6)25(22,23)18-12(21)17-10-14-9(13)15-11(20)16-10/h2-5H,1H3,(H5,13,14,15,16,17,18,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl] sulfamoyl}benzoate methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoate Not in list C12H12N6O6S Nc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2 InChI=1/C12H12N6O6S/c1-24-8(19)6-4-2-3-5-7(6)25(22,23)18-12(21)17-10-14-9(13)15-11(20)16-10/h2-5H,1H3,(H5,13,14,15,16,17,18,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl] sulfamoyl}benzoate methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoate Not in list C12H12N6O6S Nc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2 InChI=1/C12H12N6O6S/c1-24-8(19)6-4-2-3-5-7(6)25(22,23)18-12(21)17-10-14-9(13)15-11(20)16-10/h2-5H,1H3,(H5,13,14,15,16,17,18,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl] sulfamoyl}benzoate methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoate Not in list C12H12N6O6S Nc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2 InChI=1/C12H12N6O6S/c1-24-8(19)6-4-2-3-5-7(6)25(22,23)18-12(21)17-10-14-9(13)15-11(20)16-10/h2-5H,1H3,(H5,13,14,15,16,17,18,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl] sulfamoyl}benzoate methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoate Not in list C12H12N6O6S Nc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2 InChI=1/C12H12N6O6S/c1-24-8(19)6-4-2-3-5-7(6)25(22,23)18-12(21)17-10-14-9(13)15-11(20)16-10/h2-5H,1H3,(H5,13,14,15,16,17,18,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl] sulfamoyl}benzoate methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoate Not in list C12H12N6O6S Nc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2 InChI=1/C12H12N6O6S/c1-24-8(19)6-4-2-3-5-7(6)25(22,23)18-12(21)17-10-14-9(13)15-11(20)16-10/h2-5H,1H3,(H5,13,14,15,16,17,18,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl] sulfamoyl}benzoate methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoate Not in list C12H12N6O6S Nc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2 InChI=1/C12H12N6O6S/c1-24-8(19)6-4-2-3-5-7(6)25(22,23)18-12(21)17-10-14-9(13)15-11(20)16-10/h2-5H,1H3,(H5,13,14,15,16,17,18,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl] sulfamoyl}benzoate methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoate Not in list C12H12N6O6S Nc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2 InChI=1/C12H12N6O6S/c1-24-8(19)6-4-2-3-5-7(6)25(22,23)18-12(21)17-10-14-9(13)15-11(20)16-10/h2-5H,1H3,(H5,13,14,15,16,17,18,20,21) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl] sulfamoyl}benzoate methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoate Not in list C12H12N6O6S Nc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2 InChI=1/C12H12N6O6S/c1-24-8(19)6-4-2-3-5-7(6)25(22,23)18-12(21)17-10-14-9(13)15-11(20)16-10/h2-5H,1H3,(H5,13,14,15,16,17,18,20,21) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl] sulfamoyl}benzoate methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoate Not in list C12H12N6O6S Nc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2 InChI=1/C12H12N6O6S/c1-24-8(19)6-4-2-3-5-7(6)25(22,23)18-12(21)17-10-14-9(13)15-11(20)16-10/h2-5H,1H3,(H5,13,14,15,16,17,18,20,21) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl] sulfamoyl}benzoate methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoate Not in list C12H12N6O6S Nc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2 InChI=1/C12H12N6O6S/c1-24-8(19)6-4-2-3-5-7(6)25(22,23)18-12(21)17-10-14-9(13)15-11(20)16-10/h2-5H,1H3,(H5,13,14,15,16,17,18,20,21) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 2-{[(4-amino-6-ethoxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl} benzoic acid 2-{[(4-amino-6-ethoxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoic acid Not in list C13H14N6O6S CCOc2nc(N)nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)O)n2 InChI=1/C13H14N6O6S/c1-2-25-13-16-10(14)15-11(18-13)17-12(22)19-26(23,24)8-6-4-3-5-7(8)9(20)21/h3-6H,2H2,1H3,(H,20,21)(H4,14,15,16,17,18,19,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 2-{[(4-amino-6-ethoxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl} benzoic acid 2-{[(4-amino-6-ethoxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoic acid Not in list C13H14N6O6S CCOc2nc(N)nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)O)n2 InChI=1/C13H14N6O6S/c1-2-25-13-16-10(14)15-11(18-13)17-12(22)19-26(23,24)8-6-4-3-5-7(8)9(20)21/h3-6H,2H2,1H3,(H,20,21)(H4,14,15,16,17,18,19,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 2-{[(4-amino-6-ethoxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl} benzoic acid 2-{[(4-amino-6-ethoxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoic acid Not in list C13H14N6O6S CCOc2nc(N)nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)O)n2 InChI=1/C13H14N6O6S/c1-2-25-13-16-10(14)15-11(18-13)17-12(22)19-26(23,24)8-6-4-3-5-7(8)9(20)21/h3-6H,2H2,1H3,(H,20,21)(H4,14,15,16,17,18,19,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 2-{[(4-amino-6-ethoxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl} benzoic acid 2-{[(4-amino-6-ethoxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoic acid Not in list C13H14N6O6S CCOc2nc(N)nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)O)n2 InChI=1/C13H14N6O6S/c1-2-25-13-16-10(14)15-11(18-13)17-12(22)19-26(23,24)8-6-4-3-5-7(8)9(20)21/h3-6H,2H2,1H3,(H,20,21)(H4,14,15,16,17,18,19,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 2-{[(4-amino-6-ethoxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl} benzoic acid 2-{[(4-amino-6-ethoxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoic acid Not in list C13H14N6O6S CCOc2nc(N)nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)O)n2 InChI=1/C13H14N6O6S/c1-2-25-13-16-10(14)15-11(18-13)17-12(22)19-26(23,24)8-6-4-3-5-7(8)9(20)21/h3-6H,2H2,1H3,(H,20,21)(H4,14,15,16,17,18,19,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 2-{[(4-amino-6-ethoxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl} benzoic acid 2-{[(4-amino-6-ethoxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoic acid Not in list C13H14N6O6S CCOc2nc(N)nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)O)n2 InChI=1/C13H14N6O6S/c1-2-25-13-16-10(14)15-11(18-13)17-12(22)19-26(23,24)8-6-4-3-5-7(8)9(20)21/h3-6H,2H2,1H3,(H,20,21)(H4,14,15,16,17,18,19,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 2-{[(4-amino-6-ethoxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl} benzoic acid 2-{[(4-amino-6-ethoxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoic acid Not in list C13H14N6O6S CCOc2nc(N)nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)O)n2 InChI=1/C13H14N6O6S/c1-2-25-13-16-10(14)15-11(18-13)17-12(22)19-26(23,24)8-6-4-3-5-7(8)9(20)21/h3-6H,2H2,1H3,(H,20,21)(H4,14,15,16,17,18,19,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 2-{[(4-amino-6-ethoxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl} benzoic acid 2-{[(4-amino-6-ethoxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoic acid Not in list C13H14N6O6S CCOc2nc(N)nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)O)n2 InChI=1/C13H14N6O6S/c1-2-25-13-16-10(14)15-11(18-13)17-12(22)19-26(23,24)8-6-4-3-5-7(8)9(20)21/h3-6H,2H2,1H3,(H,20,21)(H4,14,15,16,17,18,19,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 2-{[(4-amino-6-ethoxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl} benzoic acid 2-{[(4-amino-6-ethoxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoic acid Not in list C13H14N6O6S CCOc2nc(N)nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)O)n2 InChI=1/C13H14N6O6S/c1-2-25-13-16-10(14)15-11(18-13)17-12(22)19-26(23,24)8-6-4-3-5-7(8)9(20)21/h3-6H,2H2,1H3,(H,20,21)(H4,14,15,16,17,18,19,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 2-{[(4-amino-6-ethoxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl} benzoic acid 2-{[(4-amino-6-ethoxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoic acid Not in list C13H14N6O6S CCOc2nc(N)nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)O)n2 InChI=1/C13H14N6O6S/c1-2-25-13-16-10(14)15-11(18-13)17-12(22)19-26(23,24)8-6-4-3-5-7(8)9(20)21/h3-6H,2H2,1H3,(H,20,21)(H4,14,15,16,17,18,19,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 2-{[(4-amino-6-ethoxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl} benzoic acid 2-{[(4-amino-6-ethoxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoic acid Not in list C13H14N6O6S CCOc2nc(N)nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)O)n2 InChI=1/C13H14N6O6S/c1-2-25-13-16-10(14)15-11(18-13)17-12(22)19-26(23,24)8-6-4-3-5-7(8)9(20)21/h3-6H,2H2,1H3,(H,20,21)(H4,14,15,16,17,18,19,22) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 2-{[(4-amino-6-ethoxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl} benzoic acid 2-{[(4-amino-6-ethoxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoic acid Not in list C13H14N6O6S CCOc2nc(N)nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)O)n2 InChI=1/C13H14N6O6S/c1-2-25-13-16-10(14)15-11(18-13)17-12(22)19-26(23,24)8-6-4-3-5-7(8)9(20)21/h3-6H,2H2,1H3,(H,20,21)(H4,14,15,16,17,18,19,22) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 2-{[(4-amino-6-ethoxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl} benzoic acid 2-{[(4-amino-6-ethoxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoic acid Not in list C13H14N6O6S CCOc2nc(N)nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)O)n2 InChI=1/C13H14N6O6S/c1-2-25-13-16-10(14)15-11(18-13)17-12(22)19-26(23,24)8-6-4-3-5-7(8)9(20)21/h3-6H,2H2,1H3,(H,20,21)(H4,14,15,16,17,18,19,22) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 2-{[(4-amino-6-ethoxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl} benzoic acid 2-{[(4-amino-6-ethoxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoic acid Not in list C13H14N6O6S CCOc2nc(N)nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)O)n2 InChI=1/C13H14N6O6S/c1-2-25-13-16-10(14)15-11(18-13)17-12(22)19-26(23,24)8-6-4-3-5-7(8)9(20)21/h3-6H,2H2,1H3,(H,20,21)(H4,14,15,16,17,18,19,22) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Ethametsulfuron methyl 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 2-sulfamoylbenzoic acid 211-174-4 632-24-6 2-sulfamoylbenzoic acid Not in list C7H7NO4S C1=CC=C(C(=C1)C(=O)O)S(=O)(=O)N InChI=1S/C7H7NO4S/c8-13(11,12)6-4-2-1-3-5(6)7(9)10/h1-4H,(H,9,10)(H2,8,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Ethametsulfuron methyl (Addendum 2) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 2-sulfamoylbenzoic acid 211-174-4 632-24-6 2-sulfamoylbenzoic acid Not in list C7H7NO4S C1=CC=C(C(=C1)C(=O)O)S(=O)(=O)N InChI=1S/C7H7NO4S/c8-13(11,12)6-4-2-1-3-5(6)7(9)10/h1-4H,(H,9,10)(H2,8,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Ethametsulfuron methyl (Addendum 2) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 2-sulfamoylbenzoic acid 211-174-4 632-24-6 2-sulfamoylbenzoic acid Not in list C7H7NO4S C1=CC=C(C(=C1)C(=O)O)S(=O)(=O)N InChI=1S/C7H7NO4S/c8-13(11,12)6-4-2-1-3-5(6)7(9)10/h1-4H,(H,9,10)(H2,8,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Ethametsulfuron methyl (Addendum 2) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 2-sulfamoylbenzoic acid 211-174-4 632-24-6 2-sulfamoylbenzoic acid Not in list C7H7NO4S C1=CC=C(C(=C1)C(=O)O)S(=O)(=O)N InChI=1S/C7H7NO4S/c8-13(11,12)6-4-2-1-3-5(6)7(9)10/h1-4H,(H,9,10)(H2,8,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Ethametsulfuron methyl (Addendum 2) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 2-sulfamoylbenzoic acid 211-174-4 632-24-6 2-sulfamoylbenzoic acid Not in list C7H7NO4S C1=CC=C(C(=C1)C(=O)O)S(=O)(=O)N InChI=1S/C7H7NO4S/c8-13(11,12)6-4-2-1-3-5(6)7(9)10/h1-4H,(H,9,10)(H2,8,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Ethametsulfuron methyl (Addendum 2) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 2-sulfamoylbenzoic acid 211-174-4 632-24-6 2-sulfamoylbenzoic acid Not in list C7H7NO4S C1=CC=C(C(=C1)C(=O)O)S(=O)(=O)N InChI=1S/C7H7NO4S/c8-13(11,12)6-4-2-1-3-5(6)7(9)10/h1-4H,(H,9,10)(H2,8,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Ethametsulfuron methyl (Addendum 2) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 2-sulfamoylbenzoic acid 211-174-4 632-24-6 2-sulfamoylbenzoic acid Not in list C7H7NO4S C1=CC=C(C(=C1)C(=O)O)S(=O)(=O)N InChI=1S/C7H7NO4S/c8-13(11,12)6-4-2-1-3-5(6)7(9)10/h1-4H,(H,9,10)(H2,8,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Ethametsulfuron methyl (Addendum 2) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 2-sulfamoylbenzoic acid 211-174-4 632-24-6 2-sulfamoylbenzoic acid Not in list C7H7NO4S C1=CC=C(C(=C1)C(=O)O)S(=O)(=O)N InChI=1S/C7H7NO4S/c8-13(11,12)6-4-2-1-3-5(6)7(9)10/h1-4H,(H,9,10)(H2,8,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Ethametsulfuron methyl (Addendum 2) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 2-sulfamoylbenzoic acid 211-174-4 632-24-6 2-sulfamoylbenzoic acid Not in list C7H7NO4S C1=CC=C(C(=C1)C(=O)O)S(=O)(=O)N InChI=1S/C7H7NO4S/c8-13(11,12)6-4-2-1-3-5(6)7(9)10/h1-4H,(H,9,10)(H2,8,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Ethametsulfuron methyl (Addendum 2) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 2-sulfamoylbenzoic acid 211-174-4 632-24-6 2-sulfamoylbenzoic acid Not in list C7H7NO4S C1=CC=C(C(=C1)C(=O)O)S(=O)(=O)N InChI=1S/C7H7NO4S/c8-13(11,12)6-4-2-1-3-5(6)7(9)10/h1-4H,(H,9,10)(H2,8,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Ethametsulfuron methyl (Addendum 2) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 2-sulfamoylbenzoic acid 211-174-4 632-24-6 2-sulfamoylbenzoic acid Not in list C7H7NO4S C1=CC=C(C(=C1)C(=O)O)S(=O)(=O)N InChI=1S/C7H7NO4S/c8-13(11,12)6-4-2-1-3-5(6)7(9)10/h1-4H,(H,9,10)(H2,8,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: The United Kingdom Ethametsulfuron methyl (Addendum 2) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 2-sulfamoylbenzoic acid 211-174-4 632-24-6 2-sulfamoylbenzoic acid Not in list C7H7NO4S C1=CC=C(C(=C1)C(=O)O)S(=O)(=O)N InChI=1S/C7H7NO4S/c8-13(11,12)6-4-2-1-3-5(6)7(9)10/h1-4H,(H,9,10)(H2,8,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: The United Kingdom Ethametsulfuron methyl (Addendum 2) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 2-sulfamoylbenzoic acid 211-174-4 632-24-6 2-sulfamoylbenzoic acid Not in list C7H7NO4S C1=CC=C(C(=C1)C(=O)O)S(=O)(=O)N InChI=1S/C7H7NO4S/c8-13(11,12)6-4-2-1-3-5(6)7(9)10/h1-4H,(H,9,10)(H2,8,11,12) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 20 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The United Kingdom Ethametsulfuron methyl (Addendum 2) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 2-sulfamoylbenzoic acid 211-174-4 632-24-6 2-sulfamoylbenzoic acid Not in list C7H7NO4S C1=CC=C(C(=C1)C(=O)O)S(=O)(=O)N InChI=1S/C7H7NO4S/c8-13(11,12)6-4-2-1-3-5(6)7(9)10/h1-4H,(H,9,10)(H2,8,11,12) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 20 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: The United Kingdom Ethametsulfuron methyl (Addendum 2) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 6-ethoxy-1,3,5-triazine-2,4-diamine 2827-44-3 6-ethoxy-1,3,5-triazine-2,4-diamine Not in list C5H9N5O CCOC1=NC(=NC(=N1)N)N InChI=1S/C5H9N5O/c1-2-11-5-9-3(6)8-4(7)10-5/h2H2,1H3,(H4,6,7,8,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Ethametsulfuron methyl (Addendum 2) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 6-ethoxy-1,3,5-triazine-2,4-diamine 2827-44-3 6-ethoxy-1,3,5-triazine-2,4-diamine Not in list C5H9N5O CCOC1=NC(=NC(=N1)N)N InChI=1S/C5H9N5O/c1-2-11-5-9-3(6)8-4(7)10-5/h2H2,1H3,(H4,6,7,8,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Ethametsulfuron methyl (Addendum 2) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 6-ethoxy-1,3,5-triazine-2,4-diamine 2827-44-3 6-ethoxy-1,3,5-triazine-2,4-diamine Not in list C5H9N5O CCOC1=NC(=NC(=N1)N)N InChI=1S/C5H9N5O/c1-2-11-5-9-3(6)8-4(7)10-5/h2H2,1H3,(H4,6,7,8,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Ethametsulfuron methyl (Addendum 2) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 6-ethoxy-1,3,5-triazine-2,4-diamine 2827-44-3 6-ethoxy-1,3,5-triazine-2,4-diamine Not in list C5H9N5O CCOC1=NC(=NC(=N1)N)N InChI=1S/C5H9N5O/c1-2-11-5-9-3(6)8-4(7)10-5/h2H2,1H3,(H4,6,7,8,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Ethametsulfuron methyl (Addendum 2) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 6-ethoxy-1,3,5-triazine-2,4-diamine 2827-44-3 6-ethoxy-1,3,5-triazine-2,4-diamine Not in list C5H9N5O CCOC1=NC(=NC(=N1)N)N InChI=1S/C5H9N5O/c1-2-11-5-9-3(6)8-4(7)10-5/h2H2,1H3,(H4,6,7,8,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Ethametsulfuron methyl (Addendum 2) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 6-ethoxy-1,3,5-triazine-2,4-diamine 2827-44-3 6-ethoxy-1,3,5-triazine-2,4-diamine Not in list C5H9N5O CCOC1=NC(=NC(=N1)N)N InChI=1S/C5H9N5O/c1-2-11-5-9-3(6)8-4(7)10-5/h2H2,1H3,(H4,6,7,8,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Ethametsulfuron methyl (Addendum 2) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 6-ethoxy-1,3,5-triazine-2,4-diamine 2827-44-3 6-ethoxy-1,3,5-triazine-2,4-diamine Not in list C5H9N5O CCOC1=NC(=NC(=N1)N)N InChI=1S/C5H9N5O/c1-2-11-5-9-3(6)8-4(7)10-5/h2H2,1H3,(H4,6,7,8,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Ethametsulfuron methyl (Addendum 2) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 6-ethoxy-1,3,5-triazine-2,4-diamine 2827-44-3 6-ethoxy-1,3,5-triazine-2,4-diamine Not in list C5H9N5O CCOC1=NC(=NC(=N1)N)N InChI=1S/C5H9N5O/c1-2-11-5-9-3(6)8-4(7)10-5/h2H2,1H3,(H4,6,7,8,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Ethametsulfuron methyl (Addendum 2) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 6-ethoxy-1,3,5-triazine-2,4-diamine 2827-44-3 6-ethoxy-1,3,5-triazine-2,4-diamine Not in list C5H9N5O CCOC1=NC(=NC(=N1)N)N InChI=1S/C5H9N5O/c1-2-11-5-9-3(6)8-4(7)10-5/h2H2,1H3,(H4,6,7,8,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Ethametsulfuron methyl (Addendum 2) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 6-ethoxy-1,3,5-triazine-2,4-diamine 2827-44-3 6-ethoxy-1,3,5-triazine-2,4-diamine Not in list C5H9N5O CCOC1=NC(=NC(=N1)N)N InChI=1S/C5H9N5O/c1-2-11-5-9-3(6)8-4(7)10-5/h2H2,1H3,(H4,6,7,8,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Ethametsulfuron methyl (Addendum 2) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 6-ethoxy-1,3,5-triazine-2,4-diamine 2827-44-3 6-ethoxy-1,3,5-triazine-2,4-diamine Not in list C5H9N5O CCOC1=NC(=NC(=N1)N)N InChI=1S/C5H9N5O/c1-2-11-5-9-3(6)8-4(7)10-5/h2H2,1H3,(H4,6,7,8,9,10) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Positive RMS: The United Kingdom Ethametsulfuron methyl (Addendum 2) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 6-ethoxy-1,3,5-triazine-2,4-diamine 2827-44-3 6-ethoxy-1,3,5-triazine-2,4-diamine Not in list C5H9N5O CCOC1=NC(=NC(=N1)N)N InChI=1S/C5H9N5O/c1-2-11-5-9-3(6)8-4(7)10-5/h2H2,1H3,(H4,6,7,8,9,10) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Ethametsulfuron methyl (Addendum 2) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 6-ethoxy-1,3,5-triazine-2,4-diamine 2827-44-3 6-ethoxy-1,3,5-triazine-2,4-diamine Not in list C5H9N5O CCOC1=NC(=NC(=N1)N)N InChI=1S/C5H9N5O/c1-2-11-5-9-3(6)8-4(7)10-5/h2H2,1H3,(H4,6,7,8,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Ethametsulfuron methyl (Addendum 2) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 6-ethoxy-1,3,5-triazine-2,4-diamine 2827-44-3 6-ethoxy-1,3,5-triazine-2,4-diamine Not in list C5H9N5O CCOC1=NC(=NC(=N1)N)N InChI=1S/C5H9N5O/c1-2-11-5-9-3(6)8-4(7)10-5/h2H2,1H3,(H4,6,7,8,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Ethametsulfuron methyl (Addendum 2) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 6-ethoxy-1,3,5-triazine-2,4-diamine 2827-44-3 6-ethoxy-1,3,5-triazine-2,4-diamine Not in list C5H9N5O CCOC1=NC(=NC(=N1)N)N InChI=1S/C5H9N5O/c1-2-11-5-9-3(6)8-4(7)10-5/h2H2,1H3,(H4,6,7,8,9,10) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: The United Kingdom Ethametsulfuron methyl (Addendum 2) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 6-ethoxy-1,3,5-triazine-2,4-diamine 2827-44-3 6-ethoxy-1,3,5-triazine-2,4-diamine Not in list C5H9N5O CCOC1=NC(=NC(=N1)N)N InChI=1S/C5H9N5O/c1-2-11-5-9-3(6)8-4(7)10-5/h2H2,1H3,(H4,6,7,8,9,10) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Positive indirect evidence-systemic toxicity RMS: The United Kingdom Ethametsulfuron methyl (Addendum 2) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl] sulfamoyl}benzoate methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoate Not in list C12H12N6O6S Nc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2 InChI=1/C12H12N6O6S/c1-24-8(19)6-4-2-3-5-7(6)25(22,23)18-12(21)17-10-14-9(13)15-11(20)16-10/h2-5H,1H3,(H5,13,14,15,16,17,18,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Ethametsulfuron methyl (Addendum 2) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl] sulfamoyl}benzoate methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoate Not in list C12H12N6O6S Nc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2 InChI=1/C12H12N6O6S/c1-24-8(19)6-4-2-3-5-7(6)25(22,23)18-12(21)17-10-14-9(13)15-11(20)16-10/h2-5H,1H3,(H5,13,14,15,16,17,18,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Ethametsulfuron methyl (Addendum 2) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl] sulfamoyl}benzoate methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoate Not in list C12H12N6O6S Nc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2 InChI=1/C12H12N6O6S/c1-24-8(19)6-4-2-3-5-7(6)25(22,23)18-12(21)17-10-14-9(13)15-11(20)16-10/h2-5H,1H3,(H5,13,14,15,16,17,18,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Ethametsulfuron methyl (Addendum 2) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl] sulfamoyl}benzoate methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoate Not in list C12H12N6O6S Nc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2 InChI=1/C12H12N6O6S/c1-24-8(19)6-4-2-3-5-7(6)25(22,23)18-12(21)17-10-14-9(13)15-11(20)16-10/h2-5H,1H3,(H5,13,14,15,16,17,18,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Ethametsulfuron methyl (Addendum 2) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl] sulfamoyl}benzoate methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoate Not in list C12H12N6O6S Nc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2 InChI=1/C12H12N6O6S/c1-24-8(19)6-4-2-3-5-7(6)25(22,23)18-12(21)17-10-14-9(13)15-11(20)16-10/h2-5H,1H3,(H5,13,14,15,16,17,18,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Ethametsulfuron methyl (Addendum 2) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl] sulfamoyl}benzoate methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoate Not in list C12H12N6O6S Nc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2 InChI=1/C12H12N6O6S/c1-24-8(19)6-4-2-3-5-7(6)25(22,23)18-12(21)17-10-14-9(13)15-11(20)16-10/h2-5H,1H3,(H5,13,14,15,16,17,18,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Ethametsulfuron methyl (Addendum 2) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl] sulfamoyl}benzoate methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoate Not in list C12H12N6O6S Nc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2 InChI=1/C12H12N6O6S/c1-24-8(19)6-4-2-3-5-7(6)25(22,23)18-12(21)17-10-14-9(13)15-11(20)16-10/h2-5H,1H3,(H5,13,14,15,16,17,18,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Ethametsulfuron methyl (Addendum 2) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl] sulfamoyl}benzoate methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoate Not in list C12H12N6O6S Nc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2 InChI=1/C12H12N6O6S/c1-24-8(19)6-4-2-3-5-7(6)25(22,23)18-12(21)17-10-14-9(13)15-11(20)16-10/h2-5H,1H3,(H5,13,14,15,16,17,18,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Ethametsulfuron methyl (Addendum 2) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl] sulfamoyl}benzoate methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoate Not in list C12H12N6O6S Nc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2 InChI=1/C12H12N6O6S/c1-24-8(19)6-4-2-3-5-7(6)25(22,23)18-12(21)17-10-14-9(13)15-11(20)16-10/h2-5H,1H3,(H5,13,14,15,16,17,18,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Ethametsulfuron methyl (Addendum 2) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl] sulfamoyl}benzoate methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoate Not in list C12H12N6O6S Nc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2 InChI=1/C12H12N6O6S/c1-24-8(19)6-4-2-3-5-7(6)25(22,23)18-12(21)17-10-14-9(13)15-11(20)16-10/h2-5H,1H3,(H5,13,14,15,16,17,18,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Ethametsulfuron methyl (Addendum 2) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl] sulfamoyl}benzoate methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoate Not in list C12H12N6O6S Nc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2 InChI=1/C12H12N6O6S/c1-24-8(19)6-4-2-3-5-7(6)25(22,23)18-12(21)17-10-14-9(13)15-11(20)16-10/h2-5H,1H3,(H5,13,14,15,16,17,18,20,21) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Ethametsulfuron methyl (Addendum 2) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl] sulfamoyl}benzoate methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoate Not in list C12H12N6O6S Nc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2 InChI=1/C12H12N6O6S/c1-24-8(19)6-4-2-3-5-7(6)25(22,23)18-12(21)17-10-14-9(13)15-11(20)16-10/h2-5H,1H3,(H5,13,14,15,16,17,18,20,21) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Ethametsulfuron methyl (Addendum 2) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl] sulfamoyl}benzoate methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoate Not in list C12H12N6O6S Nc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2 InChI=1/C12H12N6O6S/c1-24-8(19)6-4-2-3-5-7(6)25(22,23)18-12(21)17-10-14-9(13)15-11(20)16-10/h2-5H,1H3,(H5,13,14,15,16,17,18,20,21) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Ethametsulfuron methyl (Addendum 2) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl] sulfamoyl}benzoate methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoate Not in list C12H12N6O6S Nc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2 InChI=1/C12H12N6O6S/c1-24-8(19)6-4-2-3-5-7(6)25(22,23)18-12(21)17-10-14-9(13)15-11(20)16-10/h2-5H,1H3,(H5,13,14,15,16,17,18,20,21) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Ethametsulfuron methyl (Addendum 2) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 6-ethoxy-1,3,5-triazine-2,4-diamine 2827-44-3 6-ethoxy-1,3,5-triazine-2,4-diamine Not in list C5H9N5O CCOC1=NC(=NC(=N1)N)N InChI=1S/C5H9N5O/c1-2-11-5-9-3(6)8-4(7)10-5/h2H2,1H3,(H4,6,7,8,9,10) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Ethametsulfuron methyl (Addendum 4) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 6-ethoxy-1,3,5-triazine-2,4-diamine 2827-44-3 6-ethoxy-1,3,5-triazine-2,4-diamine Not in list C5H9N5O CCOC1=NC(=NC(=N1)N)N InChI=1S/C5H9N5O/c1-2-11-5-9-3(6)8-4(7)10-5/h2H2,1H3,(H4,6,7,8,9,10) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Ethametsulfuron methyl (Addendum 4) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 6-ethoxy-1,3,5-triazine-2,4-diamine 2827-44-3 6-ethoxy-1,3,5-triazine-2,4-diamine Not in list C5H9N5O CCOC1=NC(=NC(=N1)N)N InChI=1S/C5H9N5O/c1-2-11-5-9-3(6)8-4(7)10-5/h2H2,1H3,(H4,6,7,8,9,10) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female Not reported 24.0000000000 h yes, concurrent vehicle not applicable Ambiguous no evidence RMS: The United Kingdom Ethametsulfuron methyl (Addendum 4) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethametsulfuron methyl 97780-06-8 single chemical entity Component is a metabolite of the substance 6-ethoxy-1,3,5-triazine-2,4-diamine 2827-44-3 6-ethoxy-1,3,5-triazine-2,4-diamine Not in list C5H9N5O CCOC1=NC(=NC(=N1)N)N InChI=1S/C5H9N5O/c1-2-11-5-9-3(6)8-4(7)10-5/h2H2,1H3,(H4,6,7,8,9,10) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female Not reported 48.0000000000 h yes, concurrent vehicle not applicable Ambiguous no evidence RMS: The United Kingdom Ethametsulfuron methyl (Addendum 4) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl) 21Jul2014 2014 doi:10.2903/j.efsa.2014.3787
+Ethoprophos 236-152-1 13194-48-4 single chemical entity Component is identical to the substance Ethoprophos 236-152-1 13194-48-4 O-ethyl S,S-dipropyl dithiophosphate Ethoprophos C8H19O2PS2 O=P(SCCC)(OCC)SCCC InChI=1S/C8H19O2PS2/c1-4-7-12-11(9,10-6-3)13-8-5-2/h4-8H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: The United Kingdom Ethoprophos 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethoprophos 28Apr2006 2006 doi:10.2903/j.efsa.2006.66r
+Ethoprophos 236-152-1 13194-48-4 single chemical entity Component is identical to the substance Ethoprophos 236-152-1 13194-48-4 O-ethyl S,S-dipropyl dithiophosphate Ethoprophos C8H19O2PS2 O=P(SCCC)(OCC)SCCC InChI=1S/C8H19O2PS2/c1-4-7-12-11(9,10-6-3)13-8-5-2/h4-8H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: The United Kingdom Ethoprophos 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethoprophos 28Apr2006 2006 doi:10.2903/j.efsa.2006.66r
+Ethoprophos 236-152-1 13194-48-4 single chemical entity Component is identical to the substance Ethoprophos 236-152-1 13194-48-4 O-ethyl S,S-dipropyl dithiophosphate Ethoprophos C8H19O2PS2 O=P(SCCC)(OCC)SCCC InChI=1S/C8H19O2PS2/c1-4-7-12-11(9,10-6-3)13-8-5-2/h4-8H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: The United Kingdom Ethoprophos 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethoprophos 28Apr2006 2006 doi:10.2903/j.efsa.2006.66r
+Ethoprophos 236-152-1 13194-48-4 single chemical entity Component is identical to the substance Ethoprophos 236-152-1 13194-48-4 O-ethyl S,S-dipropyl dithiophosphate Ethoprophos C8H19O2PS2 O=P(SCCC)(OCC)SCCC InChI=1S/C8H19O2PS2/c1-4-7-12-11(9,10-6-3)13-8-5-2/h4-8H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: The United Kingdom Ethoprophos 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethoprophos 28Apr2006 2006 doi:10.2903/j.efsa.2006.66r
+Ethoprophos 236-152-1 13194-48-4 single chemical entity Component is identical to the substance Ethoprophos 236-152-1 13194-48-4 O-ethyl S,S-dipropyl dithiophosphate Ethoprophos C8H19O2PS2 O=P(SCCC)(OCC)SCCC InChI=1S/C8H19O2PS2/c1-4-7-12-11(9,10-6-3)13-8-5-2/h4-8H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: The United Kingdom Ethoprophos 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethoprophos 28Apr2006 2006 doi:10.2903/j.efsa.2006.66r
+Ethoprophos 236-152-1 13194-48-4 single chemical entity Component is identical to the substance Ethoprophos 236-152-1 13194-48-4 O-ethyl S,S-dipropyl dithiophosphate Ethoprophos C8H19O2PS2 O=P(SCCC)(OCC)SCCC InChI=1S/C8H19O2PS2/c1-4-7-12-11(9,10-6-3)13-8-5-2/h4-8H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: The United Kingdom Ethoprophos 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethoprophos 28Apr2006 2006 doi:10.2903/j.efsa.2006.66r
+Ethoprophos 236-152-1 13194-48-4 single chemical entity Component is identical to the substance Ethoprophos 236-152-1 13194-48-4 O-ethyl S,S-dipropyl dithiophosphate Ethoprophos C8H19O2PS2 O=P(SCCC)(OCC)SCCC InChI=1S/C8H19O2PS2/c1-4-7-12-11(9,10-6-3)13-8-5-2/h4-8H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: The United Kingdom Ethoprophos 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethoprophos 28Apr2006 2006 doi:10.2903/j.efsa.2006.66r
+Ethoprophos 236-152-1 13194-48-4 single chemical entity Component is identical to the substance Ethoprophos 236-152-1 13194-48-4 O-ethyl S,S-dipropyl dithiophosphate Ethoprophos C8H19O2PS2 O=P(SCCC)(OCC)SCCC InChI=1S/C8H19O2PS2/c1-4-7-12-11(9,10-6-3)13-8-5-2/h4-8H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: The United Kingdom Ethoprophos 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethoprophos 28Apr2006 2006 doi:10.2903/j.efsa.2006.66r
+Ethoprophos 236-152-1 13194-48-4 single chemical entity Component is identical to the substance Ethoprophos 236-152-1 13194-48-4 O-ethyl S,S-dipropyl dithiophosphate Ethoprophos C8H19O2PS2 O=P(SCCC)(OCC)SCCC InChI=1S/C8H19O2PS2/c1-4-7-12-11(9,10-6-3)13-8-5-2/h4-8H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: The United Kingdom Ethoprophos 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethoprophos 28Apr2006 2006 doi:10.2903/j.efsa.2006.66r
+Ethoprophos 236-152-1 13194-48-4 single chemical entity Component is identical to the substance Ethoprophos 236-152-1 13194-48-4 O-ethyl S,S-dipropyl dithiophosphate Ethoprophos C8H19O2PS2 O=P(SCCC)(OCC)SCCC InChI=1S/C8H19O2PS2/c1-4-7-12-11(9,10-6-3)13-8-5-2/h4-8H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: The United Kingdom Ethoprophos 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethoprophos 28Apr2006 2006 doi:10.2903/j.efsa.2006.66r
+Ethoprophos 236-152-1 13194-48-4 single chemical entity Component is identical to the substance Ethoprophos 236-152-1 13194-48-4 O-ethyl S,S-dipropyl dithiophosphate Ethoprophos C8H19O2PS2 O=P(SCCC)(OCC)SCCC InChI=1S/C8H19O2PS2/c1-4-7-12-11(9,10-6-3)13-8-5-2/h4-8H2,1-3H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: The United Kingdom Ethoprophos 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethoprophos 28Apr2006 2006 doi:10.2903/j.efsa.2006.66r
+Ethoprophos 236-152-1 13194-48-4 single chemical entity Component is identical to the substance Ethoprophos 236-152-1 13194-48-4 O-ethyl S,S-dipropyl dithiophosphate Ethoprophos C8H19O2PS2 O=P(SCCC)(OCC)SCCC InChI=1S/C8H19O2PS2/c1-4-7-12-11(9,10-6-3)13-8-5-2/h4-8H2,1-3H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Positive no information RMS: The United Kingdom Ethoprophos 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethoprophos 28Apr2006 2006 doi:10.2903/j.efsa.2006.66r
+Ethoprophos 236-152-1 13194-48-4 single chemical entity Component is identical to the substance Ethoprophos 236-152-1 13194-48-4 O-ethyl S,S-dipropyl dithiophosphate Ethoprophos C8H19O2PS2 O=P(SCCC)(OCC)SCCC InChI=1S/C8H19O2PS2/c1-4-7-12-11(9,10-6-3)13-8-5-2/h4-8H2,1-3H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Positive RMS: The United Kingdom Ethoprophos 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethoprophos 28Apr2006 2006 doi:10.2903/j.efsa.2006.66r
+Ethoprophos 236-152-1 13194-48-4 single chemical entity Component is identical to the substance Ethoprophos 236-152-1 13194-48-4 O-ethyl S,S-dipropyl dithiophosphate Ethoprophos C8H19O2PS2 O=P(SCCC)(OCC)SCCC InChI=1S/C8H19O2PS2/c1-4-7-12-11(9,10-6-3)13-8-5-2/h4-8H2,1-3H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Ethoprophos 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethoprophos 28Apr2006 2006 doi:10.2903/j.efsa.2006.66r
+Ethoprophos 236-152-1 13194-48-4 single chemical entity Component is identical to the substance Ethoprophos 236-152-1 13194-48-4 O-ethyl S,S-dipropyl dithiophosphate Ethoprophos C8H19O2PS2 O=P(SCCC)(OCC)SCCC InChI=1S/C8H19O2PS2/c1-4-7-12-11(9,10-6-3)13-8-5-2/h4-8H2,1-3H3 organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro According to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Positive RMS: The United Kingdom Ethoprophos 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethoprophos 28Apr2006 2006 doi:10.2903/j.efsa.2006.66r
+Ethoprophos 236-152-1 13194-48-4 single chemical entity Component is identical to the substance Ethoprophos 236-152-1 13194-48-4 O-ethyl S,S-dipropyl dithiophosphate Ethoprophos C8H19O2PS2 O=P(SCCC)(OCC)SCCC InChI=1S/C8H19O2PS2/c1-4-7-12-11(9,10-6-3)13-8-5-2/h4-8H2,1-3H3 organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro According to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Ethoprophos 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethoprophos 28Apr2006 2006 doi:10.2903/j.efsa.2006.66r
+Ethoprophos 236-152-1 13194-48-4 single chemical entity Component is identical to the substance Ethoprophos 236-152-1 13194-48-4 O-ethyl S,S-dipropyl dithiophosphate Ethoprophos C8H19O2PS2 O=P(SCCC)(OCC)SCCC InChI=1S/C8H19O2PS2/c1-4-7-12-11(9,10-6-3)13-8-5-2/h4-8H2,1-3H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Ethoprophos 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethoprophos 28Apr2006 2006 doi:10.2903/j.efsa.2006.66r
+Ethoprophos 236-152-1 13194-48-4 single chemical entity Component is identical to the substance Ethoprophos 236-152-1 13194-48-4 O-ethyl S,S-dipropyl dithiophosphate Ethoprophos C8H19O2PS2 O=P(SCCC)(OCC)SCCC InChI=1S/C8H19O2PS2/c1-4-7-12-11(9,10-6-3)13-8-5-2/h4-8H2,1-3H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Positive RMS: The United Kingdom Ethoprophos 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethoprophos 28Apr2006 2006 doi:10.2903/j.efsa.2006.66r
+Ethoprophos 236-152-1 13194-48-4 single chemical entity Component is identical to the substance Ethoprophos 236-152-1 13194-48-4 O-ethyl S,S-dipropyl dithiophosphate Ethoprophos C8H19O2PS2 O=P(SCCC)(OCC)SCCC InChI=1S/C8H19O2PS2/c1-4-7-12-11(9,10-6-3)13-8-5-2/h4-8H2,1-3H3 organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Ethoprophos 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethoprophos 28Apr2006 2006 doi:10.2903/j.efsa.2006.66r
+Ethoprophos 236-152-1 13194-48-4 single chemical entity Component is identical to the substance Ethoprophos 236-152-1 13194-48-4 O-ethyl S,S-dipropyl dithiophosphate Ethoprophos C8H19O2PS2 O=P(SCCC)(OCC)SCCC InChI=1S/C8H19O2PS2/c1-4-7-12-11(9,10-6-3)13-8-5-2/h4-8H2,1-3H3 organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Ethoprophos 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethoprophos 28Apr2006 2006 doi:10.2903/j.efsa.2006.66r
+Ethoprophos 236-152-1 13194-48-4 single chemical entity Component is identical to the substance Ethoprophos 236-152-1 13194-48-4 O-ethyl S,S-dipropyl dithiophosphate Ethoprophos C8H19O2PS2 O=P(SCCC)(OCC)SCCC InChI=1S/C8H19O2PS2/c1-4-7-12-11(9,10-6-3)13-8-5-2/h4-8H2,1-3H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Rat (as animal) Sprague-Dawley 10 Male/Female oral: gavage 30.0000000000 h yes not applicable Negative RMS: The United Kingdom Ethoprophos 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethoprophos 28Apr2006 2006 doi:10.2903/j.efsa.2006.66r
+Ethoprophos 236-152-1 13194-48-4 single chemical entity Component is identical to the substance Ethoprophos 236-152-1 13194-48-4 O-ethyl S,S-dipropyl dithiophosphate Ethoprophos C8H19O2PS2 O=P(SCCC)(OCC)SCCC InChI=1S/C8H19O2PS2/c1-4-7-12-11(9,10-6-3)13-8-5-2/h4-8H2,1-3H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Rat (as animal) Sprague-Dawley 10 Male/Female oral: gavage 18.0000000000 h yes not applicable Negative RMS: The United Kingdom Ethoprophos 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethoprophos 28Apr2006 2006 doi:10.2903/j.efsa.2006.66r
+Ethoprophos 236-152-1 13194-48-4 single chemical entity Component is identical to the substance Ethoprophos 236-152-1 13194-48-4 O-ethyl S,S-dipropyl dithiophosphate Ethoprophos C8H19O2PS2 O=P(SCCC)(OCC)SCCC InChI=1S/C8H19O2PS2/c1-4-7-12-11(9,10-6-3)13-8-5-2/h4-8H2,1-3H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Rat (as animal) Sprague-Dawley 10 Male/Female oral: gavage 6.0000000000 h yes not applicable Negative RMS: The United Kingdom Ethoprophos 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethoprophos 28Apr2006 2006 doi:10.2903/j.efsa.2006.66r
+Ethoprophos 236-152-1 13194-48-4 single chemical entity Component is identical to the substance Ethoprophos 236-152-1 13194-48-4 O-ethyl S,S-dipropyl dithiophosphate Ethoprophos C8H19O2PS2 O=P(SCCC)(OCC)SCCC InChI=1S/C8H19O2PS2/c1-4-7-12-11(9,10-6-3)13-8-5-2/h4-8H2,1-3H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable Rat (as animal) Sprague-Dawley 5 Male oral: gavage 6.0000000000 h yes not applicable Positive indirect evidence-systemic toxicity RMS: The United Kingdom Ethoprophos 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethoprophos 28Apr2006 2006 doi:10.2903/j.efsa.2006.66r
+Ethoprophos 236-152-1 13194-48-4 single chemical entity Component is identical to the substance Ethoprophos 236-152-1 13194-48-4 O-ethyl S,S-dipropyl dithiophosphate Ethoprophos C8H19O2PS2 O=P(SCCC)(OCC)SCCC InChI=1S/C8H19O2PS2/c1-4-7-12-11(9,10-6-3)13-8-5-2/h4-8H2,1-3H3 organic compound Other Other chromosome aberration dominant lethal assay in vivo According to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) No Acceptable Rat (as animal) Sprague-Dawley 10 Male oral: gavage 72.0000000000 h yes not applicable Positive RMS: The United Kingdom Ethoprophos 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethoprophos 28Apr2006 2006 doi:10.2903/j.efsa.2006.66r
+Ethoprophos 236-152-1 13194-48-4 single chemical entity Component is identical to the substance Ethoprophos 236-152-1 13194-48-4 O-ethyl S,S-dipropyl dithiophosphate Ethoprophos C8H19O2PS2 O=P(SCCC)(OCC)SCCC InChI=1S/C8H19O2PS2/c1-4-7-12-11(9,10-6-3)13-8-5-2/h4-8H2,1-3H3 organic compound Other Other chromosome aberration dominant lethal assay in vivo According to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) No Acceptable Rat (as animal) Crj:CD(SD) 24 Male oral: gavage 48.0000000000 h yes not applicable Negative RMS: The United Kingdom Ethoprophos 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethoprophos 28Apr2006 2006 doi:10.2903/j.efsa.2006.66r
+Dithianon 222-098-6 3347-22-6 single chemical entity Component is identical to the substance Dithianon 222-098-6 3347-22-6 5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile Dithianon C14H4N2O2S2 O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13 InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Greece Dithianon (Additional Report to DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon 25Nov2010 2010 doi:10.2903/j.efsa.2010.1904
+Dithianon 222-098-6 3347-22-6 single chemical entity Component is identical to the substance Dithianon 222-098-6 3347-22-6 5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile Dithianon C14H4N2O2S2 O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13 InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Greece Dithianon (Additional Report to DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon 25Nov2010 2010 doi:10.2903/j.efsa.2010.1904
+Dithianon 222-098-6 3347-22-6 single chemical entity Component is identical to the substance Dithianon 222-098-6 3347-22-6 5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile Dithianon C14H4N2O2S2 O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13 InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Greece Dithianon (Additional Report to DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon 25Nov2010 2010 doi:10.2903/j.efsa.2010.1904
+Dithianon 222-098-6 3347-22-6 single chemical entity Component is identical to the substance Dithianon 222-098-6 3347-22-6 5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile Dithianon C14H4N2O2S2 O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13 InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Greece Dithianon (Additional Report to DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon 25Nov2010 2010 doi:10.2903/j.efsa.2010.1904
+Dithianon 222-098-6 3347-22-6 single chemical entity Component is identical to the substance Dithianon 222-098-6 3347-22-6 5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile Dithianon C14H4N2O2S2 O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13 InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Greece Dithianon (Additional Report to DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon 25Nov2010 2010 doi:10.2903/j.efsa.2010.1904
+Dithianon 222-098-6 3347-22-6 single chemical entity Component is identical to the substance Dithianon 222-098-6 3347-22-6 5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile Dithianon C14H4N2O2S2 O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13 InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Greece Dithianon (Additional Report to DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon 25Nov2010 2010 doi:10.2903/j.efsa.2010.1904
+Dithianon 222-098-6 3347-22-6 single chemical entity Component is identical to the substance Dithianon 222-098-6 3347-22-6 5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile Dithianon C14H4N2O2S2 O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13 InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Greece Dithianon (Additional Report to DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon 25Nov2010 2010 doi:10.2903/j.efsa.2010.1904
+Dithianon 222-098-6 3347-22-6 single chemical entity Component is identical to the substance Dithianon 222-098-6 3347-22-6 5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile Dithianon C14H4N2O2S2 O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13 InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Greece Dithianon (Additional Report to DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon 25Nov2010 2010 doi:10.2903/j.efsa.2010.1904
+Dithianon 222-098-6 3347-22-6 single chemical entity Component is identical to the substance Dithianon 222-098-6 3347-22-6 5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile Dithianon C14H4N2O2S2 O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13 InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Greece Dithianon (Additional Report to DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon 25Nov2010 2010 doi:10.2903/j.efsa.2010.1904
+Dithianon 222-098-6 3347-22-6 single chemical entity Component is identical to the substance Dithianon 222-098-6 3347-22-6 5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile Dithianon C14H4N2O2S2 O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13 InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Greece Dithianon (Additional Report to DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon 25Nov2010 2010 doi:10.2903/j.efsa.2010.1904
+Dithianon 222-098-6 3347-22-6 single chemical entity Component is identical to the substance Dithianon 222-098-6 3347-22-6 5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile Dithianon C14H4N2O2S2 O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13 InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Greece Dithianon (Additional Report to DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon 25Nov2010 2010 doi:10.2903/j.efsa.2010.1904
+Dithianon 222-098-6 3347-22-6 single chemical entity Component is identical to the substance Dithianon 222-098-6 3347-22-6 5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile Dithianon C14H4N2O2S2 O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13 InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Greece Dithianon (Additional Report to DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon 25Nov2010 2010 doi:10.2903/j.efsa.2010.1904
+Dithianon 222-098-6 3347-22-6 single chemical entity Component is identical to the substance Dithianon 222-098-6 3347-22-6 5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile Dithianon C14H4N2O2S2 O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13 InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Greece Dithianon (Additional Report to DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon 25Nov2010 2010 doi:10.2903/j.efsa.2010.1904
+Dithianon 222-098-6 3347-22-6 single chemical entity Component is identical to the substance Dithianon 222-098-6 3347-22-6 5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile Dithianon C14H4N2O2S2 O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13 InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Greece Dithianon (Additional Report to DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon 25Nov2010 2010 doi:10.2903/j.efsa.2010.1904
+Dithianon 222-098-6 3347-22-6 single chemical entity Component is identical to the substance Dithianon 222-098-6 3347-22-6 5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile Dithianon C14H4N2O2S2 O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13 InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Greece Dithianon (Additional Report to DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon 25Nov2010 2010 doi:10.2903/j.efsa.2010.1904
+Dithianon 222-098-6 3347-22-6 single chemical entity Component is identical to the substance Dithianon 222-098-6 3347-22-6 5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile Dithianon C14H4N2O2S2 O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13 InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Greece Dithianon (Additional Report to DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon 25Nov2010 2010 doi:10.2903/j.efsa.2010.1904
+Dithianon 222-098-6 3347-22-6 single chemical entity Component is identical to the substance Dithianon 222-098-6 3347-22-6 5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile Dithianon C14H4N2O2S2 O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13 InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Greece Dithianon (Additional Report to DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon 25Nov2010 2010 doi:10.2903/j.efsa.2010.1904
+Dithianon 222-098-6 3347-22-6 single chemical entity Component is identical to the substance Dithianon 222-098-6 3347-22-6 5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile Dithianon C14H4N2O2S2 O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13 InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Greece Dithianon (Additional Report to DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon 25Nov2010 2010 doi:10.2903/j.efsa.2010.1904
+Dithianon 222-098-6 3347-22-6 single chemical entity Component is identical to the substance Dithianon 222-098-6 3347-22-6 5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile Dithianon C14H4N2O2S2 O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13 InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Greece Dithianon (Additional Report to DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon 25Nov2010 2010 doi:10.2903/j.efsa.2010.1904
+Dithianon 222-098-6 3347-22-6 single chemical entity Component is identical to the substance Dithianon 222-098-6 3347-22-6 5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile Dithianon C14H4N2O2S2 O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13 InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Greece Dithianon (Additional Report to DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon 25Nov2010 2010 doi:10.2903/j.efsa.2010.1904
+Dithianon 222-098-6 3347-22-6 single chemical entity Component is identical to the substance Dithianon 222-098-6 3347-22-6 5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile Dithianon C14H4N2O2S2 O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13 InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Negative RMS: Greece Dithianon (Additional Report to DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon 25Nov2010 2010 doi:10.2903/j.efsa.2010.1904
+Dithianon 222-098-6 3347-22-6 single chemical entity Component is identical to the substance Dithianon 222-098-6 3347-22-6 5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile Dithianon C14H4N2O2S2 O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13 InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: Greece Dithianon (Additional Report to DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon 25Nov2010 2010 doi:10.2903/j.efsa.2010.1904
+Dithianon 222-098-6 3347-22-6 single chemical entity Component is identical to the substance Dithianon 222-098-6 3347-22-6 5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile Dithianon C14H4N2O2S2 O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13 InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Positive RMS: Greece Dithianon (Additional Report to DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon 25Nov2010 2010 doi:10.2903/j.efsa.2010.1904
+Dithianon 222-098-6 3347-22-6 single chemical entity Component is identical to the substance Dithianon 222-098-6 3347-22-6 5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile Dithianon C14H4N2O2S2 O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13 InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Positive RMS: Greece Dithianon (Additional Report to DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon 25Nov2010 2010 doi:10.2903/j.efsa.2010.1904
+Dithianon 222-098-6 3347-22-6 single chemical entity Component is identical to the substance Dithianon 222-098-6 3347-22-6 5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile Dithianon C14H4N2O2S2 O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13 InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Positive RMS: Greece Dithianon (Additional Report to DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon 25Nov2010 2010 doi:10.2903/j.efsa.2010.1904
+Dithianon 222-098-6 3347-22-6 single chemical entity Component is identical to the substance Dithianon 222-098-6 3347-22-6 5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile Dithianon C14H4N2O2S2 O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13 InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Positive RMS: Greece Dithianon (Additional Report to DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon 25Nov2010 2010 doi:10.2903/j.efsa.2010.1904
+Dithianon 222-098-6 3347-22-6 single chemical entity Component is identical to the substance Dithianon 222-098-6 3347-22-6 5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile Dithianon C14H4N2O2S2 O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13 InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Greece Dithianon (Additional Report to DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon 25Nov2010 2010 doi:10.2903/j.efsa.2010.1904
+Dithianon 222-098-6 3347-22-6 single chemical entity Component is identical to the substance Dithianon 222-098-6 3347-22-6 5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile Dithianon C14H4N2O2S2 O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13 InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Wistar 6 Male/Female oral: gavage 48.0000000000 h yes not applicable Negative RMS: Greece Dithianon (Additional Report to DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon 25Nov2010 2010 doi:10.2903/j.efsa.2010.1904
+Dithianon 222-098-6 3347-22-6 single chemical entity Component is identical to the substance Dithianon 222-098-6 3347-22-6 5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile Dithianon C14H4N2O2S2 O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13 InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Wistar 6 Male/Female oral: gavage 24.0000000000 h yes not applicable Negative RMS: Greece Dithianon (Additional Report to DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon 25Nov2010 2010 doi:10.2903/j.efsa.2010.1904
+Dithianon 222-098-6 3347-22-6 single chemical entity Component is identical to the substance Dithianon 222-098-6 3347-22-6 5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile Dithianon C14H4N2O2S2 O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13 InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Wistar 6 Male/Female oral: gavage 6.0000000000 h yes not applicable Negative RMS: Greece Dithianon (Additional Report to DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon 25Nov2010 2010 doi:10.2903/j.efsa.2010.1904
+Dithianon 222-098-6 3347-22-6 single chemical entity Component is identical to the substance Dithianon 222-098-6 3347-22-6 5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile Dithianon C14H4N2O2S2 O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13 InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 72.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Greece Dithianon (Additional Report to DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon 25Nov2010 2010 doi:10.2903/j.efsa.2010.1904
+Dithianon 222-098-6 3347-22-6 single chemical entity Component is identical to the substance Dithianon 222-098-6 3347-22-6 5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile Dithianon C14H4N2O2S2 O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13 InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Greece Dithianon (Additional Report to DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon 25Nov2010 2010 doi:10.2903/j.efsa.2010.1904
+Dithianon 222-098-6 3347-22-6 single chemical entity Component is identical to the substance Dithianon 222-098-6 3347-22-6 5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile Dithianon C14H4N2O2S2 O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13 InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable Rat (as animal) Wistar Male/Female oral: gavage 24.0000000000 h yes not applicable Negative indirect evidence-systemic toxicity RMS: Greece Dithianon (Additional Report to DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon 25Nov2010 2010 doi:10.2903/j.efsa.2010.1904
+Dithianon 222-098-6 3347-22-6 single chemical entity Component is identical to the substance Dithianon 222-098-6 3347-22-6 5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile Dithianon C14H4N2O2S2 O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13 InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable Rat (as animal) Wistar Male/Female oral: gavage 48.0000000000 h yes not applicable Negative indirect evidence-systemic toxicity RMS: Greece Dithianon (Additional Report to DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon 25Nov2010 2010 doi:10.2903/j.efsa.2010.1904
+Dithianon 222-098-6 3347-22-6 single chemical entity Component is identical to the substance Dithianon 222-098-6 3347-22-6 5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile Dithianon C14H4N2O2S2 O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13 InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable Rat (as animal) Wistar Male/Female oral: gavage 6.0000000000 h yes not applicable Negative indirect evidence-systemic toxicity RMS: Greece Dithianon (Additional Report to DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon 25Nov2010 2010 doi:10.2903/j.efsa.2010.1904
+Dithianon 222-098-6 3347-22-6 single chemical entity Component is identical to the substance Dithianon 222-098-6 3347-22-6 5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile Dithianon C14H4N2O2S2 O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13 InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H organic compound Other Other DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo Equivalent or similar to OECD Guideline 489 Yes Acceptable Rat (as animal) Wistar 10 Male/Female oral: gavage 6.0000000000 h yes not applicable Positive RMS: Greece Dithianon (Additional Report to DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon 25Nov2010 2010 doi:10.2903/j.efsa.2010.1904
+Dithianon 222-098-6 3347-22-6 single chemical entity Component is identical to the substance Dithianon 222-098-6 3347-22-6 5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile Dithianon C14H4N2O2S2 O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13 InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H organic compound Other Other DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo Equivalent or similar to OECD Guideline 489 Yes Acceptable Rat (as animal) Wistar 10 Male/Female oral: gavage 24.0000000000 h yes not applicable Positive RMS: Greece Dithianon (Additional Report to DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon 25Nov2010 2010 doi:10.2903/j.efsa.2010.1904
+Dithianon 222-098-6 3347-22-6 single chemical entity Component is identical to the substance Dithianon 222-098-6 3347-22-6 5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile Dithianon C14H4N2O2S2 O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13 InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H organic compound Other Other DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable Rat (as animal) Sprague-Dawley Female Not reported yes, concurrent vehicle not applicable Negative RMS: Greece Dithianon (Additional Report to DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon 25Nov2010 2010 doi:10.2903/j.efsa.2010.1904
+Dithianon 222-098-6 3347-22-6 single chemical entity Component is identical to the substance Dithianon 222-098-6 3347-22-6 5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile Dithianon C14H4N2O2S2 O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13 InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H organic compound Other Other DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable Rat (as animal) Sprague-Dawley Female Not reported yes, concurrent vehicle not applicable Negative RMS: Greece Dithianon (Additional Report to DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon 25Nov2010 2010 doi:10.2903/j.efsa.2010.1904
+Dithianon 222-098-6 3347-22-6 single chemical entity Component is identical to the substance Dithianon 222-098-6 3347-22-6 5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile Dithianon C14H4N2O2S2 O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13 InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo Equivalent or similar to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) Yes Acceptable Rat (as animal) Wistar 3 Female oral: gavage 14.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Greece Dithianon (Additional Report to DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon 25Nov2010 2010 doi:10.2903/j.efsa.2010.1904
+Dithianon 222-098-6 3347-22-6 single chemical entity Component is identical to the substance Dithianon 222-098-6 3347-22-6 5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile Dithianon C14H4N2O2S2 O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13 InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo Equivalent or similar to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) Yes Acceptable Rat (as animal) Wistar 3 Female oral: gavage 3.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Greece Dithianon (Additional Report to DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon 25Nov2010 2010 doi:10.2903/j.efsa.2010.1904
+Chlorthal-dimethyl 217-464-7 1861-32-1 single chemical entity Component is identical to the substance Chlorthal-dimethyl 217-464-7 1861-32-1 Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate Chlorthal-dimethyl C10H6Cl4O4 COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Greece Chlorthal-dimethyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl 25Sep2009 2009 doi:10.2903/j.efsa.2009.202r
+Chlorthal-dimethyl 217-464-7 1861-32-1 single chemical entity Component is identical to the substance Chlorthal-dimethyl 217-464-7 1861-32-1 Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate Chlorthal-dimethyl C10H6Cl4O4 COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Greece Chlorthal-dimethyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl 25Sep2009 2009 doi:10.2903/j.efsa.2009.202r
+Chlorthal-dimethyl 217-464-7 1861-32-1 single chemical entity Component is identical to the substance Chlorthal-dimethyl 217-464-7 1861-32-1 Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate Chlorthal-dimethyl C10H6Cl4O4 COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Greece Chlorthal-dimethyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl 25Sep2009 2009 doi:10.2903/j.efsa.2009.202r
+Chlorthal-dimethyl 217-464-7 1861-32-1 single chemical entity Component is identical to the substance Chlorthal-dimethyl 217-464-7 1861-32-1 Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate Chlorthal-dimethyl C10H6Cl4O4 COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Greece Chlorthal-dimethyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl 25Sep2009 2009 doi:10.2903/j.efsa.2009.202r
+Chlorthal-dimethyl 217-464-7 1861-32-1 single chemical entity Component is identical to the substance Chlorthal-dimethyl 217-464-7 1861-32-1 Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate Chlorthal-dimethyl C10H6Cl4O4 COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Greece Chlorthal-dimethyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl 25Sep2009 2009 doi:10.2903/j.efsa.2009.202r
+Chlorthal-dimethyl 217-464-7 1861-32-1 single chemical entity Component is identical to the substance Chlorthal-dimethyl 217-464-7 1861-32-1 Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate Chlorthal-dimethyl C10H6Cl4O4 COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Greece Chlorthal-dimethyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl 25Sep2009 2009 doi:10.2903/j.efsa.2009.202r
+Chlorthal-dimethyl 217-464-7 1861-32-1 single chemical entity Component is identical to the substance Chlorthal-dimethyl 217-464-7 1861-32-1 Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate Chlorthal-dimethyl C10H6Cl4O4 COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Greece Chlorthal-dimethyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl 25Sep2009 2009 doi:10.2903/j.efsa.2009.202r
+Chlorthal-dimethyl 217-464-7 1861-32-1 single chemical entity Component is identical to the substance Chlorthal-dimethyl 217-464-7 1861-32-1 Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate Chlorthal-dimethyl C10H6Cl4O4 COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Greece Chlorthal-dimethyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl 25Sep2009 2009 doi:10.2903/j.efsa.2009.202r
+Chlorthal-dimethyl 217-464-7 1861-32-1 single chemical entity Component is identical to the substance Chlorthal-dimethyl 217-464-7 1861-32-1 Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate Chlorthal-dimethyl C10H6Cl4O4 COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Greece Chlorthal-dimethyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl 25Sep2009 2009 doi:10.2903/j.efsa.2009.202r
+Chlorthal-dimethyl 217-464-7 1861-32-1 single chemical entity Component is identical to the substance Chlorthal-dimethyl 217-464-7 1861-32-1 Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate Chlorthal-dimethyl C10H6Cl4O4 COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Greece Chlorthal-dimethyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl 25Sep2009 2009 doi:10.2903/j.efsa.2009.202r
+Chlorthal-dimethyl 217-464-7 1861-32-1 single chemical entity Component is identical to the substance Chlorthal-dimethyl 217-464-7 1861-32-1 Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate Chlorthal-dimethyl C10H6Cl4O4 COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Greece Chlorthal-dimethyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl 25Sep2009 2009 doi:10.2903/j.efsa.2009.202r
+Chlorthal-dimethyl 217-464-7 1861-32-1 single chemical entity Component is identical to the substance Chlorthal-dimethyl 217-464-7 1861-32-1 Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate Chlorthal-dimethyl C10H6Cl4O4 COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Greece Chlorthal-dimethyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl 25Sep2009 2009 doi:10.2903/j.efsa.2009.202r
+Chlorthal-dimethyl 217-464-7 1861-32-1 single chemical entity Component is identical to the substance Chlorthal-dimethyl 217-464-7 1861-32-1 Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate Chlorthal-dimethyl C10H6Cl4O4 COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Greece Chlorthal-dimethyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl 25Sep2009 2009 doi:10.2903/j.efsa.2009.202r
+Chlorthal-dimethyl 217-464-7 1861-32-1 single chemical entity Component is identical to the substance Chlorthal-dimethyl 217-464-7 1861-32-1 Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate Chlorthal-dimethyl C10H6Cl4O4 COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Greece Chlorthal-dimethyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl 25Sep2009 2009 doi:10.2903/j.efsa.2009.202r
+Chlorthal-dimethyl 217-464-7 1861-32-1 single chemical entity Component is identical to the substance Chlorthal-dimethyl 217-464-7 1861-32-1 Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate Chlorthal-dimethyl C10H6Cl4O4 COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Greece Chlorthal-dimethyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl 25Sep2009 2009 doi:10.2903/j.efsa.2009.202r
+Chlorthal-dimethyl 217-464-7 1861-32-1 single chemical entity Component is identical to the substance Chlorthal-dimethyl 217-464-7 1861-32-1 Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate Chlorthal-dimethyl C10H6Cl4O4 COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Greece Chlorthal-dimethyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl 25Sep2009 2009 doi:10.2903/j.efsa.2009.202r
+Chlorthal-dimethyl 217-464-7 1861-32-1 single chemical entity Component is identical to the substance Chlorthal-dimethyl 217-464-7 1861-32-1 Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate Chlorthal-dimethyl C10H6Cl4O4 COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Greece Chlorthal-dimethyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl 25Sep2009 2009 doi:10.2903/j.efsa.2009.202r
+Chlorthal-dimethyl 217-464-7 1861-32-1 single chemical entity Component is identical to the substance Chlorthal-dimethyl 217-464-7 1861-32-1 Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate Chlorthal-dimethyl C10H6Cl4O4 COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Greece Chlorthal-dimethyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl 25Sep2009 2009 doi:10.2903/j.efsa.2009.202r
+Chlorthal-dimethyl 217-464-7 1861-32-1 single chemical entity Component is identical to the substance Chlorthal-dimethyl 217-464-7 1861-32-1 Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate Chlorthal-dimethyl C10H6Cl4O4 COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Greece Chlorthal-dimethyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl 25Sep2009 2009 doi:10.2903/j.efsa.2009.202r
+Chlorthal-dimethyl 217-464-7 1861-32-1 single chemical entity Component is identical to the substance Chlorthal-dimethyl 217-464-7 1861-32-1 Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate Chlorthal-dimethyl C10H6Cl4O4 COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Greece Chlorthal-dimethyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl 25Sep2009 2009 doi:10.2903/j.efsa.2009.202r
+Chlorthal-dimethyl 217-464-7 1861-32-1 single chemical entity Component is identical to the substance Chlorthal-dimethyl 217-464-7 1861-32-1 Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate Chlorthal-dimethyl C10H6Cl4O4 COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Greece Chlorthal-dimethyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl 25Sep2009 2009 doi:10.2903/j.efsa.2009.202r
+Chlorthal-dimethyl 217-464-7 1861-32-1 single chemical entity Component is identical to the substance Chlorthal-dimethyl 217-464-7 1861-32-1 Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate Chlorthal-dimethyl C10H6Cl4O4 COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Greece Chlorthal-dimethyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl 25Sep2009 2009 doi:10.2903/j.efsa.2009.202r
+Chlorthal-dimethyl 217-464-7 1861-32-1 single chemical entity Component is identical to the substance Chlorthal-dimethyl 217-464-7 1861-32-1 Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate Chlorthal-dimethyl C10H6Cl4O4 COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Salmonella typhimurium (as organism) TA1978 Not reported yes, concurrent vehicle with Negative RMS: Greece Chlorthal-dimethyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl 25Sep2009 2009 doi:10.2903/j.efsa.2009.202r
+Chlorthal-dimethyl 217-464-7 1861-32-1 single chemical entity Component is identical to the substance Chlorthal-dimethyl 217-464-7 1861-32-1 Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate Chlorthal-dimethyl C10H6Cl4O4 COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Salmonella typhimurium (as organism) TA1978 Not reported yes, concurrent vehicle without Negative RMS: Greece Chlorthal-dimethyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl 25Sep2009 2009 doi:10.2903/j.efsa.2009.202r
+Chlorthal-dimethyl 217-464-7 1861-32-1 single chemical entity Component is identical to the substance Chlorthal-dimethyl 217-464-7 1861-32-1 Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate Chlorthal-dimethyl C10H6Cl4O4 COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Greece Chlorthal-dimethyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl 25Sep2009 2009 doi:10.2903/j.efsa.2009.202r
+Chlorthal-dimethyl 217-464-7 1861-32-1 single chemical entity Component is identical to the substance Chlorthal-dimethyl 217-464-7 1861-32-1 Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate Chlorthal-dimethyl C10H6Cl4O4 COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Greece Chlorthal-dimethyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl 25Sep2009 2009 doi:10.2903/j.efsa.2009.202r
+Chlorthal-dimethyl 217-464-7 1861-32-1 single chemical entity Component is identical to the substance Chlorthal-dimethyl 217-464-7 1861-32-1 Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate Chlorthal-dimethyl C10H6Cl4O4 COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Greece Chlorthal-dimethyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl 25Sep2009 2009 doi:10.2903/j.efsa.2009.202r
+Chlorthal-dimethyl 217-464-7 1861-32-1 single chemical entity Component is identical to the substance Chlorthal-dimethyl 217-464-7 1861-32-1 Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate Chlorthal-dimethyl C10H6Cl4O4 COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Greece Chlorthal-dimethyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl 25Sep2009 2009 doi:10.2903/j.efsa.2009.202r
+Chlorthal-dimethyl 217-464-7 1861-32-1 single chemical entity Component is identical to the substance Chlorthal-dimethyl 217-464-7 1861-32-1 Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate Chlorthal-dimethyl C10H6Cl4O4 COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro According to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Positive RMS: Greece Chlorthal-dimethyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl 25Sep2009 2009 doi:10.2903/j.efsa.2009.202r
+Chlorthal-dimethyl 217-464-7 1861-32-1 single chemical entity Component is identical to the substance Chlorthal-dimethyl 217-464-7 1861-32-1 Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate Chlorthal-dimethyl C10H6Cl4O4 COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro According to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Positive RMS: Greece Chlorthal-dimethyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl 25Sep2009 2009 doi:10.2903/j.efsa.2009.202r
+Chlorthal-dimethyl 217-464-7 1861-32-1 single chemical entity Component is identical to the substance Chlorthal-dimethyl 217-464-7 1861-32-1 Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate Chlorthal-dimethyl C10H6Cl4O4 COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Greece Chlorthal-dimethyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl 25Sep2009 2009 doi:10.2903/j.efsa.2009.202r
+Chlorthal-dimethyl 217-464-7 1861-32-1 single chemical entity Component is identical to the substance Chlorthal-dimethyl 217-464-7 1861-32-1 Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate Chlorthal-dimethyl C10H6Cl4O4 COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle with Negative RMS: Greece Chlorthal-dimethyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl 25Sep2009 2009 doi:10.2903/j.efsa.2009.202r
+Chlorthal-dimethyl 217-464-7 1861-32-1 single chemical entity Component is identical to the substance Chlorthal-dimethyl 217-464-7 1861-32-1 Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate Chlorthal-dimethyl C10H6Cl4O4 COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Sprague-Dawley 5 Male intraperitoneal 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Greece Chlorthal-dimethyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl 25Sep2009 2009 doi:10.2903/j.efsa.2009.202r
+Chlorthal-dimethyl 217-464-7 1861-32-1 single chemical entity Component is identical to the substance Chlorthal-dimethyl 217-464-7 1861-32-1 Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate Chlorthal-dimethyl C10H6Cl4O4 COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 5 Male oral: unspecified 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Greece Chlorthal-dimethyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl 25Sep2009 2009 doi:10.2903/j.efsa.2009.202r
+Chlorthal-dimethyl 217-464-7 1861-32-1 single chemical entity Component is identical to the substance Chlorthal-dimethyl 217-464-7 1861-32-1 Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate Chlorthal-dimethyl C10H6Cl4O4 COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 5 Male oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Greece Chlorthal-dimethyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl 25Sep2009 2009 doi:10.2903/j.efsa.2009.202r
+Chlorthal-dimethyl 217-464-7 1861-32-1 single chemical entity Component is identical to the substance Chlorthal-dimethyl 217-464-7 1861-32-1 Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate Chlorthal-dimethyl C10H6Cl4O4 COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) Yes Acceptable Rat (as animal) Crj:CD(SD) 10 Male oral: gavage yes not applicable Positive RMS: Greece Chlorthal-dimethyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl 25Sep2009 2009 doi:10.2903/j.efsa.2009.202r
+Chlorthal-dimethyl 217-464-7 1861-32-1 single chemical entity Component is a metabolite of the substance 2,3,5,6-tetrachloroterephthalic acid 2136-79-0 2,3,5,6-tetrachloroterephthalic acid Not in list C8H2Cl4O4 C1(=C(C(=C(C(=C1Cl)Cl)C(=O)O)Cl)Cl)C(=O)O InChI=1S/C8H2Cl4O4/c9-3-1(7(13)14)4(10)6(12)2(5(3)11)8(15)16/h(H,13,14)(H,15,16) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Greece Chlorthal-dimethyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl 25Sep2009 2009 doi:10.2903/j.efsa.2009.202r
+Chlorthal-dimethyl 217-464-7 1861-32-1 single chemical entity Component is a metabolite of the substance 2,3,5,6-tetrachloroterephthalic acid 2136-79-0 2,3,5,6-tetrachloroterephthalic acid Not in list C8H2Cl4O4 C1(=C(C(=C(C(=C1Cl)Cl)C(=O)O)Cl)Cl)C(=O)O InChI=1S/C8H2Cl4O4/c9-3-1(7(13)14)4(10)6(12)2(5(3)11)8(15)16/h(H,13,14)(H,15,16) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Greece Chlorthal-dimethyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl 25Sep2009 2009 doi:10.2903/j.efsa.2009.202r
+Chlorthal-dimethyl 217-464-7 1861-32-1 single chemical entity Component is a metabolite of the substance 2,3,5,6-tetrachloroterephthalic acid 2136-79-0 2,3,5,6-tetrachloroterephthalic acid Not in list C8H2Cl4O4 C1(=C(C(=C(C(=C1Cl)Cl)C(=O)O)Cl)Cl)C(=O)O InChI=1S/C8H2Cl4O4/c9-3-1(7(13)14)4(10)6(12)2(5(3)11)8(15)16/h(H,13,14)(H,15,16) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Greece Chlorthal-dimethyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl 25Sep2009 2009 doi:10.2903/j.efsa.2009.202r
+Chlorthal-dimethyl 217-464-7 1861-32-1 single chemical entity Component is a metabolite of the substance 2,3,5,6-tetrachloroterephthalic acid 2136-79-0 2,3,5,6-tetrachloroterephthalic acid Not in list C8H2Cl4O4 C1(=C(C(=C(C(=C1Cl)Cl)C(=O)O)Cl)Cl)C(=O)O InChI=1S/C8H2Cl4O4/c9-3-1(7(13)14)4(10)6(12)2(5(3)11)8(15)16/h(H,13,14)(H,15,16) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Greece Chlorthal-dimethyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl 25Sep2009 2009 doi:10.2903/j.efsa.2009.202r
+Chlorthal-dimethyl 217-464-7 1861-32-1 single chemical entity Component is a metabolite of the substance 2,3,5,6-tetrachloroterephthalic acid 2136-79-0 2,3,5,6-tetrachloroterephthalic acid Not in list C8H2Cl4O4 C1(=C(C(=C(C(=C1Cl)Cl)C(=O)O)Cl)Cl)C(=O)O InChI=1S/C8H2Cl4O4/c9-3-1(7(13)14)4(10)6(12)2(5(3)11)8(15)16/h(H,13,14)(H,15,16) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Greece Chlorthal-dimethyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl 25Sep2009 2009 doi:10.2903/j.efsa.2009.202r
+Chlorthal-dimethyl 217-464-7 1861-32-1 single chemical entity Component is a metabolite of the substance 2,3,5,6-tetrachloroterephthalic acid 2136-79-0 2,3,5,6-tetrachloroterephthalic acid Not in list C8H2Cl4O4 C1(=C(C(=C(C(=C1Cl)Cl)C(=O)O)Cl)Cl)C(=O)O InChI=1S/C8H2Cl4O4/c9-3-1(7(13)14)4(10)6(12)2(5(3)11)8(15)16/h(H,13,14)(H,15,16) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Greece Chlorthal-dimethyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl 25Sep2009 2009 doi:10.2903/j.efsa.2009.202r
+Chlorthal-dimethyl 217-464-7 1861-32-1 single chemical entity Component is a metabolite of the substance 2,3,5,6-tetrachloroterephthalic acid 2136-79-0 2,3,5,6-tetrachloroterephthalic acid Not in list C8H2Cl4O4 C1(=C(C(=C(C(=C1Cl)Cl)C(=O)O)Cl)Cl)C(=O)O InChI=1S/C8H2Cl4O4/c9-3-1(7(13)14)4(10)6(12)2(5(3)11)8(15)16/h(H,13,14)(H,15,16) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Greece Chlorthal-dimethyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl 25Sep2009 2009 doi:10.2903/j.efsa.2009.202r
+Chlorthal-dimethyl 217-464-7 1861-32-1 single chemical entity Component is a metabolite of the substance 2,3,5,6-tetrachloroterephthalic acid 2136-79-0 2,3,5,6-tetrachloroterephthalic acid Not in list C8H2Cl4O4 C1(=C(C(=C(C(=C1Cl)Cl)C(=O)O)Cl)Cl)C(=O)O InChI=1S/C8H2Cl4O4/c9-3-1(7(13)14)4(10)6(12)2(5(3)11)8(15)16/h(H,13,14)(H,15,16) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Greece Chlorthal-dimethyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl 25Sep2009 2009 doi:10.2903/j.efsa.2009.202r
+Chlorthal-dimethyl 217-464-7 1861-32-1 single chemical entity Component is a metabolite of the substance 2,3,5,6-tetrachloroterephthalic acid 2136-79-0 2,3,5,6-tetrachloroterephthalic acid Not in list C8H2Cl4O4 C1(=C(C(=C(C(=C1Cl)Cl)C(=O)O)Cl)Cl)C(=O)O InChI=1S/C8H2Cl4O4/c9-3-1(7(13)14)4(10)6(12)2(5(3)11)8(15)16/h(H,13,14)(H,15,16) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Greece Chlorthal-dimethyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl 25Sep2009 2009 doi:10.2903/j.efsa.2009.202r
+Chlorthal-dimethyl 217-464-7 1861-32-1 single chemical entity Component is a metabolite of the substance 2,3,5,6-tetrachloroterephthalic acid 2136-79-0 2,3,5,6-tetrachloroterephthalic acid Not in list C8H2Cl4O4 C1(=C(C(=C(C(=C1Cl)Cl)C(=O)O)Cl)Cl)C(=O)O InChI=1S/C8H2Cl4O4/c9-3-1(7(13)14)4(10)6(12)2(5(3)11)8(15)16/h(H,13,14)(H,15,16) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Greece Chlorthal-dimethyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl 25Sep2009 2009 doi:10.2903/j.efsa.2009.202r
+Chlorthal-dimethyl 217-464-7 1861-32-1 single chemical entity Component is a metabolite of the substance 2,3,5,6-tetrachloroterephthalic acid 2136-79-0 2,3,5,6-tetrachloroterephthalic acid Not in list C8H2Cl4O4 C1(=C(C(=C(C(=C1Cl)Cl)C(=O)O)Cl)Cl)C(=O)O InChI=1S/C8H2Cl4O4/c9-3-1(7(13)14)4(10)6(12)2(5(3)11)8(15)16/h(H,13,14)(H,15,16) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: Greece Chlorthal-dimethyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl 25Sep2009 2009 doi:10.2903/j.efsa.2009.202r
+Chlorthal-dimethyl 217-464-7 1861-32-1 single chemical entity Component is a metabolite of the substance 2,3,5,6-tetrachloroterephthalic acid 2136-79-0 2,3,5,6-tetrachloroterephthalic acid Not in list C8H2Cl4O4 C1(=C(C(=C(C(=C1Cl)Cl)C(=O)O)Cl)Cl)C(=O)O InChI=1S/C8H2Cl4O4/c9-3-1(7(13)14)4(10)6(12)2(5(3)11)8(15)16/h(H,13,14)(H,15,16) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: Greece Chlorthal-dimethyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl 25Sep2009 2009 doi:10.2903/j.efsa.2009.202r
+Chlorthal-dimethyl 217-464-7 1861-32-1 single chemical entity Component is a metabolite of the substance 2,3,5,6-tetrachloroterephthalic acid 2136-79-0 2,3,5,6-tetrachloroterephthalic acid Not in list C8H2Cl4O4 C1(=C(C(=C(C(=C1Cl)Cl)C(=O)O)Cl)Cl)C(=O)O InChI=1S/C8H2Cl4O4/c9-3-1(7(13)14)4(10)6(12)2(5(3)11)8(15)16/h(H,13,14)(H,15,16) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro According to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: Greece Chlorthal-dimethyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl 25Sep2009 2009 doi:10.2903/j.efsa.2009.202r
+Chlorthal-dimethyl 217-464-7 1861-32-1 single chemical entity Component is a metabolite of the substance 2,3,5,6-tetrachloroterephthalic acid 2136-79-0 2,3,5,6-tetrachloroterephthalic acid Not in list C8H2Cl4O4 C1(=C(C(=C(C(=C1Cl)Cl)C(=O)O)Cl)Cl)C(=O)O InChI=1S/C8H2Cl4O4/c9-3-1(7(13)14)4(10)6(12)2(5(3)11)8(15)16/h(H,13,14)(H,15,16) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro According to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: Greece Chlorthal-dimethyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl 25Sep2009 2009 doi:10.2903/j.efsa.2009.202r
+Chlorthal-dimethyl 217-464-7 1861-32-1 single chemical entity Component is a metabolite of the substance 2,3,5,6-tetrachloroterephthalic acid 2136-79-0 2,3,5,6-tetrachloroterephthalic acid Not in list C8H2Cl4O4 C1(=C(C(=C(C(=C1Cl)Cl)C(=O)O)Cl)Cl)C(=O)O InChI=1S/C8H2Cl4O4/c9-3-1(7(13)14)4(10)6(12)2(5(3)11)8(15)16/h(H,13,14)(H,15,16) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes without Negative RMS: Greece Chlorthal-dimethyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl 25Sep2009 2009 doi:10.2903/j.efsa.2009.202r
+Chlorthal-dimethyl 217-464-7 1861-32-1 single chemical entity Component is a metabolite of the substance 2,3,5,6-tetrachloroterephthalic acid 2136-79-0 2,3,5,6-tetrachloroterephthalic acid Not in list C8H2Cl4O4 C1(=C(C(=C(C(=C1Cl)Cl)C(=O)O)Cl)Cl)C(=O)O InChI=1S/C8H2Cl4O4/c9-3-1(7(13)14)4(10)6(12)2(5(3)11)8(15)16/h(H,13,14)(H,15,16) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes with Negative RMS: Greece Chlorthal-dimethyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl 25Sep2009 2009 doi:10.2903/j.efsa.2009.202r
+Chlorthal-dimethyl 217-464-7 1861-32-1 single chemical entity Component is a metabolite of the substance 2,3,5,6-tetrachloroterephthalic acid 2136-79-0 2,3,5,6-tetrachloroterephthalic acid Not in list C8H2Cl4O4 C1(=C(C(=C(C(=C1Cl)Cl)C(=O)O)Cl)Cl)C(=O)O InChI=1S/C8H2Cl4O4/c9-3-1(7(13)14)4(10)6(12)2(5(3)11)8(15)16/h(H,13,14)(H,15,16) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Swiss 7 Male/Female Not reported 72.0000000000 h yes not applicable Negative direct evidence-cytotoxicity$indirect evidence-systemic toxicity RMS: Greece Chlorthal-dimethyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl 25Sep2009 2009 doi:10.2903/j.efsa.2009.202r
+Chlorthal-dimethyl 217-464-7 1861-32-1 single chemical entity Component is a metabolite of the substance 2,3,5,6-tetrachloroterephthalic acid 2136-79-0 2,3,5,6-tetrachloroterephthalic acid Not in list C8H2Cl4O4 C1(=C(C(=C(C(=C1Cl)Cl)C(=O)O)Cl)Cl)C(=O)O InChI=1S/C8H2Cl4O4/c9-3-1(7(13)14)4(10)6(12)2(5(3)11)8(15)16/h(H,13,14)(H,15,16) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Swiss 7 Male/Female Not reported 24.0000000000 h yes not applicable Negative direct evidence-cytotoxicity$indirect evidence-systemic toxicity RMS: Greece Chlorthal-dimethyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl 25Sep2009 2009 doi:10.2903/j.efsa.2009.202r
+Chlorthal-dimethyl 217-464-7 1861-32-1 single chemical entity Component is a metabolite of the substance 2,3,5,6-tetrachloroterephthalic acid 2136-79-0 2,3,5,6-tetrachloroterephthalic acid Not in list C8H2Cl4O4 C1(=C(C(=C(C(=C1Cl)Cl)C(=O)O)Cl)Cl)C(=O)O InChI=1S/C8H2Cl4O4/c9-3-1(7(13)14)4(10)6(12)2(5(3)11)8(15)16/h(H,13,14)(H,15,16) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Swiss 7 Male/Female Not reported 48.0000000000 h yes not applicable Positive direct evidence-cytotoxicity$indirect evidence-systemic toxicity RMS: Greece Chlorthal-dimethyl 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl 25Sep2009 2009 doi:10.2903/j.efsa.2009.202r
+Chlorthal-dimethyl 217-464-7 1861-32-1 single chemical entity Component is a metabolite of the substance 4-carbomethoxy-2,3,5,6-tetrachlorobenzoic acid 887-54-7 2,3,5,6-tetrachloro-4-methoxycarbonylbenzoic acid Not in list C9H4Cl4O4 COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)O)Cl)Cl InChI=1S/C9H4Cl4O4/c1-17-9(16)3-6(12)4(10)2(8(14)15)5(11)7(3)13/h1H3,(H,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Greece Chlorthal-dimethyl (Addendum 1 to annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl 25Sep2009 2009 doi:10.2903/j.efsa.2009.202r
+Chlorthal-dimethyl 217-464-7 1861-32-1 single chemical entity Component is a metabolite of the substance 4-carbomethoxy-2,3,5,6-tetrachlorobenzoic acid 887-54-7 2,3,5,6-tetrachloro-4-methoxycarbonylbenzoic acid Not in list C9H4Cl4O4 COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)O)Cl)Cl InChI=1S/C9H4Cl4O4/c1-17-9(16)3-6(12)4(10)2(8(14)15)5(11)7(3)13/h1H3,(H,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Greece Chlorthal-dimethyl (Addendum 1 to annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl 25Sep2009 2009 doi:10.2903/j.efsa.2009.202r
+Chlorthal-dimethyl 217-464-7 1861-32-1 single chemical entity Component is a metabolite of the substance 4-carbomethoxy-2,3,5,6-tetrachlorobenzoic acid 887-54-7 2,3,5,6-tetrachloro-4-methoxycarbonylbenzoic acid Not in list C9H4Cl4O4 COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)O)Cl)Cl InChI=1S/C9H4Cl4O4/c1-17-9(16)3-6(12)4(10)2(8(14)15)5(11)7(3)13/h1H3,(H,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Greece Chlorthal-dimethyl (Addendum 1 to annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl 25Sep2009 2009 doi:10.2903/j.efsa.2009.202r
+Chlorthal-dimethyl 217-464-7 1861-32-1 single chemical entity Component is a metabolite of the substance 4-carbomethoxy-2,3,5,6-tetrachlorobenzoic acid 887-54-7 2,3,5,6-tetrachloro-4-methoxycarbonylbenzoic acid Not in list C9H4Cl4O4 COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)O)Cl)Cl InChI=1S/C9H4Cl4O4/c1-17-9(16)3-6(12)4(10)2(8(14)15)5(11)7(3)13/h1H3,(H,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Greece Chlorthal-dimethyl (Addendum 1 to annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl 25Sep2009 2009 doi:10.2903/j.efsa.2009.202r
+Chlorthal-dimethyl 217-464-7 1861-32-1 single chemical entity Component is a metabolite of the substance 4-carbomethoxy-2,3,5,6-tetrachlorobenzoic acid 887-54-7 2,3,5,6-tetrachloro-4-methoxycarbonylbenzoic acid Not in list C9H4Cl4O4 COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)O)Cl)Cl InChI=1S/C9H4Cl4O4/c1-17-9(16)3-6(12)4(10)2(8(14)15)5(11)7(3)13/h1H3,(H,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Greece Chlorthal-dimethyl (Addendum 1 to annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl 25Sep2009 2009 doi:10.2903/j.efsa.2009.202r
+Chlorthal-dimethyl 217-464-7 1861-32-1 single chemical entity Component is a metabolite of the substance 4-carbomethoxy-2,3,5,6-tetrachlorobenzoic acid 887-54-7 2,3,5,6-tetrachloro-4-methoxycarbonylbenzoic acid Not in list C9H4Cl4O4 COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)O)Cl)Cl InChI=1S/C9H4Cl4O4/c1-17-9(16)3-6(12)4(10)2(8(14)15)5(11)7(3)13/h1H3,(H,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Greece Chlorthal-dimethyl (Addendum 1 to annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl 25Sep2009 2009 doi:10.2903/j.efsa.2009.202r
+Chlorthal-dimethyl 217-464-7 1861-32-1 single chemical entity Component is a metabolite of the substance 4-carbomethoxy-2,3,5,6-tetrachlorobenzoic acid 887-54-7 2,3,5,6-tetrachloro-4-methoxycarbonylbenzoic acid Not in list C9H4Cl4O4 COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)O)Cl)Cl InChI=1S/C9H4Cl4O4/c1-17-9(16)3-6(12)4(10)2(8(14)15)5(11)7(3)13/h1H3,(H,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: Greece Chlorthal-dimethyl (Addendum 1 to annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl 25Sep2009 2009 doi:10.2903/j.efsa.2009.202r
+Chlorthal-dimethyl 217-464-7 1861-32-1 single chemical entity Component is a metabolite of the substance 4-carbomethoxy-2,3,5,6-tetrachlorobenzoic acid 887-54-7 2,3,5,6-tetrachloro-4-methoxycarbonylbenzoic acid Not in list C9H4Cl4O4 COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)O)Cl)Cl InChI=1S/C9H4Cl4O4/c1-17-9(16)3-6(12)4(10)2(8(14)15)5(11)7(3)13/h1H3,(H,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Greece Chlorthal-dimethyl (Addendum 1 to annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl 25Sep2009 2009 doi:10.2903/j.efsa.2009.202r
+Chlorthal-dimethyl 217-464-7 1861-32-1 single chemical entity Component is a metabolite of the substance 4-carbomethoxy-2,3,5,6-tetrachlorobenzoic acid 887-54-7 2,3,5,6-tetrachloro-4-methoxycarbonylbenzoic acid Not in list C9H4Cl4O4 COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)O)Cl)Cl InChI=1S/C9H4Cl4O4/c1-17-9(16)3-6(12)4(10)2(8(14)15)5(11)7(3)13/h1H3,(H,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: Greece Chlorthal-dimethyl (Addendum 1 to annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl 25Sep2009 2009 doi:10.2903/j.efsa.2009.202r
+Chlorthal-dimethyl 217-464-7 1861-32-1 single chemical entity Component is a metabolite of the substance 4-carbomethoxy-2,3,5,6-tetrachlorobenzoic acid 887-54-7 2,3,5,6-tetrachloro-4-methoxycarbonylbenzoic acid Not in list C9H4Cl4O4 COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)O)Cl)Cl InChI=1S/C9H4Cl4O4/c1-17-9(16)3-6(12)4(10)2(8(14)15)5(11)7(3)13/h1H3,(H,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Greece Chlorthal-dimethyl (Addendum 1 to annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl 25Sep2009 2009 doi:10.2903/j.efsa.2009.202r
+Benalaxyl-M 98243-83-5 single chemical entity Component is identical to the substance Benalaxyl-M 98243-83-5 methyl N-(2,6-dimethylphenyl)-N-(phenylacetyl)-D-alaninate Benalaxyl-M C20H23NO3 C[C@@H](N(C(=O)Cc1ccccc1)c2c(C)cccc2C)C(=O)OC InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3/t16-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is identical to the substance Benalaxyl-M 98243-83-5 methyl N-(2,6-dimethylphenyl)-N-(phenylacetyl)-D-alaninate Benalaxyl-M C20H23NO3 C[C@@H](N(C(=O)Cc1ccccc1)c2c(C)cccc2C)C(=O)OC InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3/t16-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is identical to the substance Benalaxyl-M 98243-83-5 methyl N-(2,6-dimethylphenyl)-N-(phenylacetyl)-D-alaninate Benalaxyl-M C20H23NO3 C[C@@H](N(C(=O)Cc1ccccc1)c2c(C)cccc2C)C(=O)OC InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3/t16-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is identical to the substance Benalaxyl-M 98243-83-5 methyl N-(2,6-dimethylphenyl)-N-(phenylacetyl)-D-alaninate Benalaxyl-M C20H23NO3 C[C@@H](N(C(=O)Cc1ccccc1)c2c(C)cccc2C)C(=O)OC InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3/t16-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is identical to the substance Benalaxyl-M 98243-83-5 methyl N-(2,6-dimethylphenyl)-N-(phenylacetyl)-D-alaninate Benalaxyl-M C20H23NO3 C[C@@H](N(C(=O)Cc1ccccc1)c2c(C)cccc2C)C(=O)OC InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3/t16-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is identical to the substance Benalaxyl-M 98243-83-5 methyl N-(2,6-dimethylphenyl)-N-(phenylacetyl)-D-alaninate Benalaxyl-M C20H23NO3 C[C@@H](N(C(=O)Cc1ccccc1)c2c(C)cccc2C)C(=O)OC InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3/t16-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is identical to the substance Benalaxyl-M 98243-83-5 methyl N-(2,6-dimethylphenyl)-N-(phenylacetyl)-D-alaninate Benalaxyl-M C20H23NO3 C[C@@H](N(C(=O)Cc1ccccc1)c2c(C)cccc2C)C(=O)OC InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3/t16-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is identical to the substance Benalaxyl-M 98243-83-5 methyl N-(2,6-dimethylphenyl)-N-(phenylacetyl)-D-alaninate Benalaxyl-M C20H23NO3 C[C@@H](N(C(=O)Cc1ccccc1)c2c(C)cccc2C)C(=O)OC InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3/t16-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is identical to the substance Benalaxyl-M 98243-83-5 methyl N-(2,6-dimethylphenyl)-N-(phenylacetyl)-D-alaninate Benalaxyl-M C20H23NO3 C[C@@H](N(C(=O)Cc1ccccc1)c2c(C)cccc2C)C(=O)OC InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3/t16-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is identical to the substance Benalaxyl-M 98243-83-5 methyl N-(2,6-dimethylphenyl)-N-(phenylacetyl)-D-alaninate Benalaxyl-M C20H23NO3 C[C@@H](N(C(=O)Cc1ccccc1)c2c(C)cccc2C)C(=O)OC InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3/t16-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is part of a group assessment Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is part of a group assessment Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is part of a group assessment Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is part of a group assessment Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is part of a group assessment Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is part of a group assessment Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is part of a group assessment Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is part of a group assessment Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is part of a group assessment Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is part of a group assessment Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is part of a group assessment Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is part of a group assessment Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is part of a group assessment Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is part of a group assessment Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is part of a group assessment Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is part of a group assessment Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is part of a group assessment Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is part of a group assessment Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is part of a group assessment Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is part of a group assessment Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is part of a group assessment Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro Equivalent or similar to OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay) Yes Acceptable Saccharomyces cerevisiae (as organism) D4 Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is part of a group assessment Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro Equivalent or similar to OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay) Yes Acceptable Saccharomyces cerevisiae (as organism) D4 Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is part of a group assessment Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation yeast cytogenetic assay in vitro According to OECD Guideline 480 (Genetic Toxicology: Saccharomyces cerevisiae, Gene Mutation Assay) No Acceptable Schizosaccharomyces pombe (as organism) Not reported yes with Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is part of a group assessment Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation yeast cytogenetic assay in vitro According to OECD Guideline 480 (Genetic Toxicology: Saccharomyces cerevisiae, Gene Mutation Assay) No Acceptable Schizosaccharomyces pombe (as organism) Not reported yes without Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is identical to the substance Benalaxyl-M 98243-83-5 methyl N-(2,6-dimethylphenyl)-N-(phenylacetyl)-D-alaninate Benalaxyl-M C20H23NO3 C[C@@H](N(C(=O)Cc1ccccc1)c2c(C)cccc2C)C(=O)OC InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3/t16-/m1/s1 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is identical to the substance Benalaxyl-M 98243-83-5 methyl N-(2,6-dimethylphenyl)-N-(phenylacetyl)-D-alaninate Benalaxyl-M C20H23NO3 C[C@@H](N(C(=O)Cc1ccccc1)c2c(C)cccc2C)C(=O)OC InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3/t16-/m1/s1 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is part of a group assessment Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is part of a group assessment Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is identical to the substance Benalaxyl-M 98243-83-5 methyl N-(2,6-dimethylphenyl)-N-(phenylacetyl)-D-alaninate Benalaxyl-M C20H23NO3 C[C@@H](N(C(=O)Cc1ccccc1)c2c(C)cccc2C)C(=O)OC InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3/t16-/m1/s1 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is identical to the substance Benalaxyl-M 98243-83-5 methyl N-(2,6-dimethylphenyl)-N-(phenylacetyl)-D-alaninate Benalaxyl-M C20H23NO3 C[C@@H](N(C(=O)Cc1ccccc1)c2c(C)cccc2C)C(=O)OC InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3/t16-/m1/s1 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is part of a group assessment Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is part of a group assessment Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is part of a group assessment Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is part of a group assessment Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is part of a group assessment Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is identical to the substance Benalaxyl-M 98243-83-5 methyl N-(2,6-dimethylphenyl)-N-(phenylacetyl)-D-alaninate Benalaxyl-M C20H23NO3 C[C@@H](N(C(=O)Cc1ccccc1)c2c(C)cccc2C)C(=O)OC InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3/t16-/m1/s1 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female intraperitoneal 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is identical to the substance Benalaxyl-M 98243-83-5 methyl N-(2,6-dimethylphenyl)-N-(phenylacetyl)-D-alaninate Benalaxyl-M C20H23NO3 C[C@@H](N(C(=O)Cc1ccccc1)c2c(C)cccc2C)C(=O)OC InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3/t16-/m1/s1 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female intraperitoneal 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is part of a group assessment Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable Rat (as animal) Not reported 10 Male/Female intraperitoneal 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is part of a group assessment Benalaxyl 275-728-7 71626-11-4 Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate Benalaxyl C20H23NO3 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2 InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable Rat (as animal) Not reported 10 Male/Female intraperitoneal 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Portugal Benalaxyl-M 2003 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Cyantraniliprole 736994-63-1 single chemical entity Component is identical to the substance Cyantraniliprole 736994-63-1 3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Not in list C19H14BrClN6O2 CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is identical to the substance Cyantraniliprole 736994-63-1 3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Not in list C19H14BrClN6O2 CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is identical to the substance Cyantraniliprole 736994-63-1 3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Not in list C19H14BrClN6O2 CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is identical to the substance Cyantraniliprole 736994-63-1 3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Not in list C19H14BrClN6O2 CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is identical to the substance Cyantraniliprole 736994-63-1 3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Not in list C19H14BrClN6O2 CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is identical to the substance Cyantraniliprole 736994-63-1 3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Not in list C19H14BrClN6O2 CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is identical to the substance Cyantraniliprole 736994-63-1 3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Not in list C19H14BrClN6O2 CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is identical to the substance Cyantraniliprole 736994-63-1 3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Not in list C19H14BrClN6O2 CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is identical to the substance Cyantraniliprole 736994-63-1 3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Not in list C19H14BrClN6O2 CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is identical to the substance Cyantraniliprole 736994-63-1 3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Not in list C19H14BrClN6O2 CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is identical to the substance Cyantraniliprole 736994-63-1 3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Not in list C19H14BrClN6O2 CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is identical to the substance Cyantraniliprole 736994-63-1 3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Not in list C19H14BrClN6O2 CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is identical to the substance Cyantraniliprole 736994-63-1 3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Not in list C19H14BrClN6O2 CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is identical to the substance Cyantraniliprole 736994-63-1 3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Not in list C19H14BrClN6O2 CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is identical to the substance Cyantraniliprole 736994-63-1 3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Not in list C19H14BrClN6O2 CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is identical to the substance Cyantraniliprole 736994-63-1 3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Not in list C19H14BrClN6O2 CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is identical to the substance Cyantraniliprole 736994-63-1 3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Not in list C19H14BrClN6O2 CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is identical to the substance Cyantraniliprole 736994-63-1 3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Not in list C19H14BrClN6O2 CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is identical to the substance Cyantraniliprole 736994-63-1 3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Not in list C19H14BrClN6O2 CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is identical to the substance Cyantraniliprole 736994-63-1 3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Not in list C19H14BrClN6O2 CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is identical to the substance Cyantraniliprole 736994-63-1 3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Not in list C19H14BrClN6O2 CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is identical to the substance Cyantraniliprole 736994-63-1 3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Not in list C19H14BrClN6O2 CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is identical to the substance Cyantraniliprole 736994-63-1 3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Not in list C19H14BrClN6O2 CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is identical to the substance Cyantraniliprole 736994-63-1 3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Not in list C19H14BrClN6O2 CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is identical to the substance Cyantraniliprole 736994-63-1 3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Not in list C19H14BrClN6O2 CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is identical to the substance Cyantraniliprole 736994-63-1 3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Not in list C19H14BrClN6O2 CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is identical to the substance Cyantraniliprole 736994-63-1 3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Not in list C19H14BrClN6O2 CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is identical to the substance Cyantraniliprole 736994-63-1 3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Not in list C19H14BrClN6O2 CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is identical to the substance Cyantraniliprole 736994-63-1 3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Not in list C19H14BrClN6O2 CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is identical to the substance Cyantraniliprole 736994-63-1 3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Not in list C19H14BrClN6O2 CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is identical to the substance Cyantraniliprole 736994-63-1 3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Not in list C19H14BrClN6O2 CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is identical to the substance Cyantraniliprole 736994-63-1 3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Not in list C19H14BrClN6O2 CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is identical to the substance Cyantraniliprole 736994-63-1 3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Not in list C19H14BrClN6O2 CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is identical to the substance Cyantraniliprole 736994-63-1 3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Not in list C19H14BrClN6O2 CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is identical to the substance Cyantraniliprole 736994-63-1 3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Not in list C19H14BrClN6O2 CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is identical to the substance Cyantraniliprole 736994-63-1 3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Not in list C19H14BrClN6O2 CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is identical to the substance Cyantraniliprole 736994-63-1 3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Not in list C19H14BrClN6O2 CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is identical to the substance Cyantraniliprole 736994-63-1 3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Not in list C19H14BrClN6O2 CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is identical to the substance Cyantraniliprole 736994-63-1 3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Not in list C19H14BrClN6O2 CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is identical to the substance Cyantraniliprole 736994-63-1 3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Not in list C19H14BrClN6O2 CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is identical to the substance Cyantraniliprole 736994-63-1 3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Not in list C19H14BrClN6O2 CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 20 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is identical to the substance Cyantraniliprole 736994-63-1 3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Not in list C19H14BrClN6O2 CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 20 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is a metabolite of the substance 4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid 4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid Not in list C19H15BrClN5O4 O=C(O)c3cc(C)c(NC(=O)c2cc(Br)nn2c1ncccc1Cl)c(c3)C(=O)NC InChI=1/C19H15BrClN5O4/c1-9-6-10(19(29)30)7-11(17(27)22-2)15(9)24-18(28)13-8-14(20)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)(H,29,30) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is a metabolite of the substance 4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid 4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid Not in list C19H15BrClN5O4 O=C(O)c3cc(C)c(NC(=O)c2cc(Br)nn2c1ncccc1Cl)c(c3)C(=O)NC InChI=1/C19H15BrClN5O4/c1-9-6-10(19(29)30)7-11(17(27)22-2)15(9)24-18(28)13-8-14(20)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)(H,29,30) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is a metabolite of the substance 4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid 4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid Not in list C19H15BrClN5O4 O=C(O)c3cc(C)c(NC(=O)c2cc(Br)nn2c1ncccc1Cl)c(c3)C(=O)NC InChI=1/C19H15BrClN5O4/c1-9-6-10(19(29)30)7-11(17(27)22-2)15(9)24-18(28)13-8-14(20)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)(H,29,30) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is a metabolite of the substance 4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid 4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid Not in list C19H15BrClN5O4 O=C(O)c3cc(C)c(NC(=O)c2cc(Br)nn2c1ncccc1Cl)c(c3)C(=O)NC InChI=1/C19H15BrClN5O4/c1-9-6-10(19(29)30)7-11(17(27)22-2)15(9)24-18(28)13-8-14(20)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)(H,29,30) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is a metabolite of the substance 4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid 4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid Not in list C19H15BrClN5O4 O=C(O)c3cc(C)c(NC(=O)c2cc(Br)nn2c1ncccc1Cl)c(c3)C(=O)NC InChI=1/C19H15BrClN5O4/c1-9-6-10(19(29)30)7-11(17(27)22-2)15(9)24-18(28)13-8-14(20)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)(H,29,30) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is a metabolite of the substance 4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid 4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid Not in list C19H15BrClN5O4 O=C(O)c3cc(C)c(NC(=O)c2cc(Br)nn2c1ncccc1Cl)c(c3)C(=O)NC InChI=1/C19H15BrClN5O4/c1-9-6-10(19(29)30)7-11(17(27)22-2)15(9)24-18(28)13-8-14(20)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)(H,29,30) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is a metabolite of the substance 4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid 4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid Not in list C19H15BrClN5O4 O=C(O)c3cc(C)c(NC(=O)c2cc(Br)nn2c1ncccc1Cl)c(c3)C(=O)NC InChI=1/C19H15BrClN5O4/c1-9-6-10(19(29)30)7-11(17(27)22-2)15(9)24-18(28)13-8-14(20)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)(H,29,30) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is a metabolite of the substance 4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid 4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid Not in list C19H15BrClN5O4 O=C(O)c3cc(C)c(NC(=O)c2cc(Br)nn2c1ncccc1Cl)c(c3)C(=O)NC InChI=1/C19H15BrClN5O4/c1-9-6-10(19(29)30)7-11(17(27)22-2)15(9)24-18(28)13-8-14(20)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)(H,29,30) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is a metabolite of the substance 4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid 4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid Not in list C19H15BrClN5O4 O=C(O)c3cc(C)c(NC(=O)c2cc(Br)nn2c1ncccc1Cl)c(c3)C(=O)NC InChI=1/C19H15BrClN5O4/c1-9-6-10(19(29)30)7-11(17(27)22-2)15(9)24-18(28)13-8-14(20)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)(H,29,30) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is a metabolite of the substance 4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid 4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid Not in list C19H15BrClN5O4 O=C(O)c3cc(C)c(NC(=O)c2cc(Br)nn2c1ncccc1Cl)c(c3)C(=O)NC InChI=1/C19H15BrClN5O4/c1-9-6-10(19(29)30)7-11(17(27)22-2)15(9)24-18(28)13-8-14(20)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)(H,29,30) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is a metabolite of the substance 4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid 4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid Not in list C19H15BrClN5O4 O=C(O)c3cc(C)c(NC(=O)c2cc(Br)nn2c1ncccc1Cl)c(c3)C(=O)NC InChI=1/C19H15BrClN5O4/c1-9-6-10(19(29)30)7-11(17(27)22-2)15(9)24-18(28)13-8-14(20)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)(H,29,30) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is a metabolite of the substance 4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid 4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid Not in list C19H15BrClN5O4 O=C(O)c3cc(C)c(NC(=O)c2cc(Br)nn2c1ncccc1Cl)c(c3)C(=O)NC InChI=1/C19H15BrClN5O4/c1-9-6-10(19(29)30)7-11(17(27)22-2)15(9)24-18(28)13-8-14(20)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)(H,29,30) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is a metabolite of the substance 4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid 4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid Not in list C19H15BrClN5O4 O=C(O)c3cc(C)c(NC(=O)c2cc(Br)nn2c1ncccc1Cl)c(c3)C(=O)NC InChI=1/C19H15BrClN5O4/c1-9-6-10(19(29)30)7-11(17(27)22-2)15(9)24-18(28)13-8-14(20)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)(H,29,30) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is a metabolite of the substance 4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid 4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid Not in list C19H15BrClN5O4 O=C(O)c3cc(C)c(NC(=O)c2cc(Br)nn2c1ncccc1Cl)c(c3)C(=O)NC InChI=1/C19H15BrClN5O4/c1-9-6-10(19(29)30)7-11(17(27)22-2)15(9)24-18(28)13-8-14(20)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)(H,29,30) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is a metabolite of the substance 2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-8-methyl-4-oxo-1,4-dihydroquinazoline-6-carboxylic acid 2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-8-methyl-4-oxo-1,4-dihydroquinazoline-6-carboxylic acid Not in list C18H11BrClN5O3 O=C(O)c1cc2C(=O)N=C(Nc2c(C)c1)c4cc(Br)nn4c3ncccc3Cl InChI=1/C18H11BrClN5O3/c1-8-5-9(18(27)28)6-10-14(8)22-15(23-17(10)26)12-7-13(19)24-25(12)16-11(20)3-2-4-21-16/h2-7H,1H3,(H,27,28)(H,22,23,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is a metabolite of the substance 2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-8-methyl-4-oxo-1,4-dihydroquinazoline-6-carboxylic acid 2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-8-methyl-4-oxo-1,4-dihydroquinazoline-6-carboxylic acid Not in list C18H11BrClN5O3 O=C(O)c1cc2C(=O)N=C(Nc2c(C)c1)c4cc(Br)nn4c3ncccc3Cl InChI=1/C18H11BrClN5O3/c1-8-5-9(18(27)28)6-10-14(8)22-15(23-17(10)26)12-7-13(19)24-25(12)16-11(20)3-2-4-21-16/h2-7H,1H3,(H,27,28)(H,22,23,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is a metabolite of the substance 2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-8-methyl-4-oxo-1,4-dihydroquinazoline-6-carboxylic acid 2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-8-methyl-4-oxo-1,4-dihydroquinazoline-6-carboxylic acid Not in list C18H11BrClN5O3 O=C(O)c1cc2C(=O)N=C(Nc2c(C)c1)c4cc(Br)nn4c3ncccc3Cl InChI=1/C18H11BrClN5O3/c1-8-5-9(18(27)28)6-10-14(8)22-15(23-17(10)26)12-7-13(19)24-25(12)16-11(20)3-2-4-21-16/h2-7H,1H3,(H,27,28)(H,22,23,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is a metabolite of the substance 2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-8-methyl-4-oxo-1,4-dihydroquinazoline-6-carboxylic acid 2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-8-methyl-4-oxo-1,4-dihydroquinazoline-6-carboxylic acid Not in list C18H11BrClN5O3 O=C(O)c1cc2C(=O)N=C(Nc2c(C)c1)c4cc(Br)nn4c3ncccc3Cl InChI=1/C18H11BrClN5O3/c1-8-5-9(18(27)28)6-10-14(8)22-15(23-17(10)26)12-7-13(19)24-25(12)16-11(20)3-2-4-21-16/h2-7H,1H3,(H,27,28)(H,22,23,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is a metabolite of the substance 2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-8-methyl-4-oxo-1,4-dihydroquinazoline-6-carboxylic acid 2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-8-methyl-4-oxo-1,4-dihydroquinazoline-6-carboxylic acid Not in list C18H11BrClN5O3 O=C(O)c1cc2C(=O)N=C(Nc2c(C)c1)c4cc(Br)nn4c3ncccc3Cl InChI=1/C18H11BrClN5O3/c1-8-5-9(18(27)28)6-10-14(8)22-15(23-17(10)26)12-7-13(19)24-25(12)16-11(20)3-2-4-21-16/h2-7H,1H3,(H,27,28)(H,22,23,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is a metabolite of the substance 2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-8-methyl-4-oxo-1,4-dihydroquinazoline-6-carboxylic acid 2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-8-methyl-4-oxo-1,4-dihydroquinazoline-6-carboxylic acid Not in list C18H11BrClN5O3 O=C(O)c1cc2C(=O)N=C(Nc2c(C)c1)c4cc(Br)nn4c3ncccc3Cl InChI=1/C18H11BrClN5O3/c1-8-5-9(18(27)28)6-10-14(8)22-15(23-17(10)26)12-7-13(19)24-25(12)16-11(20)3-2-4-21-16/h2-7H,1H3,(H,27,28)(H,22,23,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is a metabolite of the substance 2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-8-methyl-4-oxo-1,4-dihydroquinazoline-6-carboxylic acid 2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-8-methyl-4-oxo-1,4-dihydroquinazoline-6-carboxylic acid Not in list C18H11BrClN5O3 O=C(O)c1cc2C(=O)N=C(Nc2c(C)c1)c4cc(Br)nn4c3ncccc3Cl InChI=1/C18H11BrClN5O3/c1-8-5-9(18(27)28)6-10-14(8)22-15(23-17(10)26)12-7-13(19)24-25(12)16-11(20)3-2-4-21-16/h2-7H,1H3,(H,27,28)(H,22,23,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is a metabolite of the substance 2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-8-methyl-4-oxo-1,4-dihydroquinazoline-6-carboxylic acid 2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-8-methyl-4-oxo-1,4-dihydroquinazoline-6-carboxylic acid Not in list C18H11BrClN5O3 O=C(O)c1cc2C(=O)N=C(Nc2c(C)c1)c4cc(Br)nn4c3ncccc3Cl InChI=1/C18H11BrClN5O3/c1-8-5-9(18(27)28)6-10-14(8)22-15(23-17(10)26)12-7-13(19)24-25(12)16-11(20)3-2-4-21-16/h2-7H,1H3,(H,27,28)(H,22,23,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is a metabolite of the substance 2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-8-methyl-4-oxo-1,4-dihydroquinazoline-6-carboxylic acid 2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-8-methyl-4-oxo-1,4-dihydroquinazoline-6-carboxylic acid Not in list C18H11BrClN5O3 O=C(O)c1cc2C(=O)N=C(Nc2c(C)c1)c4cc(Br)nn4c3ncccc3Cl InChI=1/C18H11BrClN5O3/c1-8-5-9(18(27)28)6-10-14(8)22-15(23-17(10)26)12-7-13(19)24-25(12)16-11(20)3-2-4-21-16/h2-7H,1H3,(H,27,28)(H,22,23,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is a metabolite of the substance 2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-8-methyl-4-oxo-1,4-dihydroquinazoline-6-carboxylic acid 2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-8-methyl-4-oxo-1,4-dihydroquinazoline-6-carboxylic acid Not in list C18H11BrClN5O3 O=C(O)c1cc2C(=O)N=C(Nc2c(C)c1)c4cc(Br)nn4c3ncccc3Cl InChI=1/C18H11BrClN5O3/c1-8-5-9(18(27)28)6-10-14(8)22-15(23-17(10)26)12-7-13(19)24-25(12)16-11(20)3-2-4-21-16/h2-7H,1H3,(H,27,28)(H,22,23,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is a metabolite of the substance 2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-8-methyl-4-oxo-1,4-dihydroquinazoline-6-carboxylic acid 2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-8-methyl-4-oxo-1,4-dihydroquinazoline-6-carboxylic acid Not in list C18H11BrClN5O3 O=C(O)c1cc2C(=O)N=C(Nc2c(C)c1)c4cc(Br)nn4c3ncccc3Cl InChI=1/C18H11BrClN5O3/c1-8-5-9(18(27)28)6-10-14(8)22-15(23-17(10)26)12-7-13(19)24-25(12)16-11(20)3-2-4-21-16/h2-7H,1H3,(H,27,28)(H,22,23,26) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is a metabolite of the substance 2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-8-methyl-4-oxo-1,4-dihydroquinazoline-6-carboxylic acid 2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-8-methyl-4-oxo-1,4-dihydroquinazoline-6-carboxylic acid Not in list C18H11BrClN5O3 O=C(O)c1cc2C(=O)N=C(Nc2c(C)c1)c4cc(Br)nn4c3ncccc3Cl InChI=1/C18H11BrClN5O3/c1-8-5-9(18(27)28)6-10-14(8)22-15(23-17(10)26)12-7-13(19)24-25(12)16-11(20)3-2-4-21-16/h2-7H,1H3,(H,27,28)(H,22,23,26) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is a metabolite of the substance 2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-8-methyl-4-oxo-1,4-dihydroquinazoline-6-carboxylic acid 2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-8-methyl-4-oxo-1,4-dihydroquinazoline-6-carboxylic acid Not in list C18H11BrClN5O3 O=C(O)c1cc2C(=O)N=C(Nc2c(C)c1)c4cc(Br)nn4c3ncccc3Cl InChI=1/C18H11BrClN5O3/c1-8-5-9(18(27)28)6-10-14(8)22-15(23-17(10)26)12-7-13(19)24-25(12)16-11(20)3-2-4-21-16/h2-7H,1H3,(H,27,28)(H,22,23,26) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is a metabolite of the substance 2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-8-methyl-4-oxo-1,4-dihydroquinazoline-6-carboxylic acid 2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-8-methyl-4-oxo-1,4-dihydroquinazoline-6-carboxylic acid Not in list C18H11BrClN5O3 O=C(O)c1cc2C(=O)N=C(Nc2c(C)c1)c4cc(Br)nn4c3ncccc3Cl InChI=1/C18H11BrClN5O3/c1-8-5-9(18(27)28)6-10-14(8)22-15(23-17(10)26)12-7-13(19)24-25(12)16-11(20)3-2-4-21-16/h2-7H,1H3,(H,27,28)(H,22,23,26) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is a metabolite of the substance 3-bromo-N-methyl-1H-pyrazole-5-carboxamide 3-bromo-N-methyl-1H-pyrazole-5-carboxamide Not in list C5H6BrN3O O=C(NC)c1cc(Br)nn1 InChI=1/C5H6BrN3O/c1-7-5(10)3-2-4(6)9-8-3/h2H,1H3,(H,7,10)(H,8,9) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is a metabolite of the substance 3-bromo-N-methyl-1H-pyrazole-5-carboxamide 3-bromo-N-methyl-1H-pyrazole-5-carboxamide Not in list C5H6BrN3O O=C(NC)c1cc(Br)nn1 InChI=1/C5H6BrN3O/c1-7-5(10)3-2-4(6)9-8-3/h2H,1H3,(H,7,10)(H,8,9) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is a metabolite of the substance 3-bromo-N-methyl-1H-pyrazole-5-carboxamide 3-bromo-N-methyl-1H-pyrazole-5-carboxamide Not in list C5H6BrN3O O=C(NC)c1cc(Br)nn1 InChI=1/C5H6BrN3O/c1-7-5(10)3-2-4(6)9-8-3/h2H,1H3,(H,7,10)(H,8,9) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is a metabolite of the substance 3-bromo-N-methyl-1H-pyrazole-5-carboxamide 3-bromo-N-methyl-1H-pyrazole-5-carboxamide Not in list C5H6BrN3O O=C(NC)c1cc(Br)nn1 InChI=1/C5H6BrN3O/c1-7-5(10)3-2-4(6)9-8-3/h2H,1H3,(H,7,10)(H,8,9) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is a metabolite of the substance 3-bromo-N-methyl-1H-pyrazole-5-carboxamide 3-bromo-N-methyl-1H-pyrazole-5-carboxamide Not in list C5H6BrN3O O=C(NC)c1cc(Br)nn1 InChI=1/C5H6BrN3O/c1-7-5(10)3-2-4(6)9-8-3/h2H,1H3,(H,7,10)(H,8,9) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is a metabolite of the substance 3-bromo-N-methyl-1H-pyrazole-5-carboxamide 3-bromo-N-methyl-1H-pyrazole-5-carboxamide Not in list C5H6BrN3O O=C(NC)c1cc(Br)nn1 InChI=1/C5H6BrN3O/c1-7-5(10)3-2-4(6)9-8-3/h2H,1H3,(H,7,10)(H,8,9) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is a metabolite of the substance 3-bromo-N-methyl-1H-pyrazole-5-carboxamide 3-bromo-N-methyl-1H-pyrazole-5-carboxamide Not in list C5H6BrN3O O=C(NC)c1cc(Br)nn1 InChI=1/C5H6BrN3O/c1-7-5(10)3-2-4(6)9-8-3/h2H,1H3,(H,7,10)(H,8,9) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is a metabolite of the substance 3-bromo-N-methyl-1H-pyrazole-5-carboxamide 3-bromo-N-methyl-1H-pyrazole-5-carboxamide Not in list C5H6BrN3O O=C(NC)c1cc(Br)nn1 InChI=1/C5H6BrN3O/c1-7-5(10)3-2-4(6)9-8-3/h2H,1H3,(H,7,10)(H,8,9) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is a metabolite of the substance 3-bromo-N-methyl-1H-pyrazole-5-carboxamide 3-bromo-N-methyl-1H-pyrazole-5-carboxamide Not in list C5H6BrN3O O=C(NC)c1cc(Br)nn1 InChI=1/C5H6BrN3O/c1-7-5(10)3-2-4(6)9-8-3/h2H,1H3,(H,7,10)(H,8,9) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is a metabolite of the substance 3-bromo-N-methyl-1H-pyrazole-5-carboxamide 3-bromo-N-methyl-1H-pyrazole-5-carboxamide Not in list C5H6BrN3O O=C(NC)c1cc(Br)nn1 InChI=1/C5H6BrN3O/c1-7-5(10)3-2-4(6)9-8-3/h2H,1H3,(H,7,10)(H,8,9) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is a metabolite of the substance 6-chloro-4-methyl-11-oxo-11H-pyrido[2,1-b]quinazoline-2-carbonitrile 6-chloro-4-methyl-11-oxo-11H-pyrido[2,1-b]quinazoline-2-carbonitrile Not in list C14H8ClN3O Cc3cc(C#N)cc2c3N=C1C(Cl)=CC=CN1C2=O InChI=1/C14H8ClN3O/c1-8-5-9(7-16)6-10-12(8)17-13-11(15)3-2-4-18(13)14(10)19/h2-6H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is a metabolite of the substance 6-chloro-4-methyl-11-oxo-11H-pyrido[2,1-b]quinazoline-2-carbonitrile 6-chloro-4-methyl-11-oxo-11H-pyrido[2,1-b]quinazoline-2-carbonitrile Not in list C14H8ClN3O Cc3cc(C#N)cc2c3N=C1C(Cl)=CC=CN1C2=O InChI=1/C14H8ClN3O/c1-8-5-9(7-16)6-10-12(8)17-13-11(15)3-2-4-18(13)14(10)19/h2-6H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is a metabolite of the substance 6-chloro-4-methyl-11-oxo-11H-pyrido[2,1-b]quinazoline-2-carbonitrile 6-chloro-4-methyl-11-oxo-11H-pyrido[2,1-b]quinazoline-2-carbonitrile Not in list C14H8ClN3O Cc3cc(C#N)cc2c3N=C1C(Cl)=CC=CN1C2=O InChI=1/C14H8ClN3O/c1-8-5-9(7-16)6-10-12(8)17-13-11(15)3-2-4-18(13)14(10)19/h2-6H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is a metabolite of the substance 6-chloro-4-methyl-11-oxo-11H-pyrido[2,1-b]quinazoline-2-carbonitrile 6-chloro-4-methyl-11-oxo-11H-pyrido[2,1-b]quinazoline-2-carbonitrile Not in list C14H8ClN3O Cc3cc(C#N)cc2c3N=C1C(Cl)=CC=CN1C2=O InChI=1/C14H8ClN3O/c1-8-5-9(7-16)6-10-12(8)17-13-11(15)3-2-4-18(13)14(10)19/h2-6H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is a metabolite of the substance 6-chloro-4-methyl-11-oxo-11H-pyrido[2,1-b]quinazoline-2-carbonitrile 6-chloro-4-methyl-11-oxo-11H-pyrido[2,1-b]quinazoline-2-carbonitrile Not in list C14H8ClN3O Cc3cc(C#N)cc2c3N=C1C(Cl)=CC=CN1C2=O InChI=1/C14H8ClN3O/c1-8-5-9(7-16)6-10-12(8)17-13-11(15)3-2-4-18(13)14(10)19/h2-6H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is a metabolite of the substance 6-chloro-4-methyl-11-oxo-11H-pyrido[2,1-b]quinazoline-2-carbonitrile 6-chloro-4-methyl-11-oxo-11H-pyrido[2,1-b]quinazoline-2-carbonitrile Not in list C14H8ClN3O Cc3cc(C#N)cc2c3N=C1C(Cl)=CC=CN1C2=O InChI=1/C14H8ClN3O/c1-8-5-9(7-16)6-10-12(8)17-13-11(15)3-2-4-18(13)14(10)19/h2-6H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is a metabolite of the substance 6-chloro-4-methyl-11-oxo-11H-pyrido[2,1-b]quinazoline-2-carbonitrile 6-chloro-4-methyl-11-oxo-11H-pyrido[2,1-b]quinazoline-2-carbonitrile Not in list C14H8ClN3O Cc3cc(C#N)cc2c3N=C1C(Cl)=CC=CN1C2=O InChI=1/C14H8ClN3O/c1-8-5-9(7-16)6-10-12(8)17-13-11(15)3-2-4-18(13)14(10)19/h2-6H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is a metabolite of the substance 6-chloro-4-methyl-11-oxo-11H-pyrido[2,1-b]quinazoline-2-carbonitrile 6-chloro-4-methyl-11-oxo-11H-pyrido[2,1-b]quinazoline-2-carbonitrile Not in list C14H8ClN3O Cc3cc(C#N)cc2c3N=C1C(Cl)=CC=CN1C2=O InChI=1/C14H8ClN3O/c1-8-5-9(7-16)6-10-12(8)17-13-11(15)3-2-4-18(13)14(10)19/h2-6H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is a metabolite of the substance 6-chloro-4-methyl-11-oxo-11H-pyrido[2,1-b]quinazoline-2-carbonitrile 6-chloro-4-methyl-11-oxo-11H-pyrido[2,1-b]quinazoline-2-carbonitrile Not in list C14H8ClN3O Cc3cc(C#N)cc2c3N=C1C(Cl)=CC=CN1C2=O InChI=1/C14H8ClN3O/c1-8-5-9(7-16)6-10-12(8)17-13-11(15)3-2-4-18(13)14(10)19/h2-6H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is a metabolite of the substance 6-chloro-4-methyl-11-oxo-11H-pyrido[2,1-b]quinazoline-2-carbonitrile 6-chloro-4-methyl-11-oxo-11H-pyrido[2,1-b]quinazoline-2-carbonitrile Not in list C14H8ClN3O Cc3cc(C#N)cc2c3N=C1C(Cl)=CC=CN1C2=O InChI=1/C14H8ClN3O/c1-8-5-9(7-16)6-10-12(8)17-13-11(15)3-2-4-18(13)14(10)19/h2-6H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) fibroblast Not reported no data without Positive RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA94 Not reported no data with Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA94 Not reported no data without Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA92 Not reported no data with Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA92 Not reported no data without Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Geraniol 269-750-6 106-24-1 single chemical entity Component is identical to the substance Geraniol 269-750-6 106-24-1 (2E)-3,7-dimethylocta-2,6-dien-1-ol geraniol C10H18O CC(=CCCC(=CCO)C)C InChI=1S/C10H18O/c1-9(2)5-4-6-10(3)7-8-11/h5,7,11H,4,6,8H2,1-3H3/b10-7+ organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: The United Kingdom Geraniol 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance geraniol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2915
+Geraniol 269-750-6 106-24-1 single chemical entity Component is identical to the substance Geraniol 269-750-6 106-24-1 (2E)-3,7-dimethylocta-2,6-dien-1-ol geraniol C10H18O CC(=CCCC(=CCO)C)C InChI=1S/C10H18O/c1-9(2)5-4-6-10(3)7-8-11/h5,7,11H,4,6,8H2,1-3H3/b10-7+ organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) fibroblast Not reported no data without Inconclusive RMS: The United Kingdom Geraniol 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance geraniol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2915
+Geraniol 269-750-6 106-24-1 single chemical entity Component is identical to the substance Geraniol 269-750-6 106-24-1 (2E)-3,7-dimethylocta-2,6-dien-1-ol geraniol C10H18O CC(=CCCC(=CCO)C)C InChI=1S/C10H18O/c1-9(2)5-4-6-10(3)7-8-11/h5,7,11H,4,6,8H2,1-3H3/b10-7+ organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: The United Kingdom Geraniol 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance geraniol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2915
+Geraniol 269-750-6 106-24-1 single chemical entity Component is identical to the substance Geraniol 269-750-6 106-24-1 (2E)-3,7-dimethylocta-2,6-dien-1-ol geraniol C10H18O CC(=CCCC(=CCO)C)C InChI=1S/C10H18O/c1-9(2)5-4-6-10(3)7-8-11/h5,7,11H,4,6,8H2,1-3H3/b10-7+ organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA92 Not reported no data with Negative RMS: The United Kingdom Geraniol 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance geraniol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2915
+Geraniol 269-750-6 106-24-1 single chemical entity Component is identical to the substance Geraniol 269-750-6 106-24-1 (2E)-3,7-dimethylocta-2,6-dien-1-ol geraniol C10H18O CC(=CCCC(=CCO)C)C InChI=1S/C10H18O/c1-9(2)5-4-6-10(3)7-8-11/h5,7,11H,4,6,8H2,1-3H3/b10-7+ organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: The United Kingdom Geraniol 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance geraniol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2915
+Geraniol 269-750-6 106-24-1 single chemical entity Component is identical to the substance Geraniol 269-750-6 106-24-1 (2E)-3,7-dimethylocta-2,6-dien-1-ol geraniol C10H18O CC(=CCCC(=CCO)C)C InChI=1S/C10H18O/c1-9(2)5-4-6-10(3)7-8-11/h5,7,11H,4,6,8H2,1-3H3/b10-7+ organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA94 Not reported no data with Negative RMS: The United Kingdom Geraniol 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance geraniol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2915
+Geraniol 269-750-6 106-24-1 single chemical entity Component is identical to the substance Geraniol 269-750-6 106-24-1 (2E)-3,7-dimethylocta-2,6-dien-1-ol geraniol C10H18O CC(=CCCC(=CCO)C)C InChI=1S/C10H18O/c1-9(2)5-4-6-10(3)7-8-11/h5,7,11H,4,6,8H2,1-3H3/b10-7+ organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: The United Kingdom Geraniol 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance geraniol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2915
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA1530 Not reported no data with Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is a metabolite of the substance 3-piperidyl-1-(3’-methoxy-4’-hydroxyphenyl)-1-propanone 1-(4-hydroxy-3-methoxyphenyl)-3-(piperidin-1-yl)propan-1-one Not in list C15H21NO3 Oc1ccc(cc1OC)C(=O)CCN2CCCCC2 InChI=1/C15H21NO3/c1-19-15-11-12(5-6-14(15)18)13(17)7-10-16-8-3-2-4-9-16/h5-6,11,18H,2-4,7-10H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA1530 Not reported no data with Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is a metabolite of the substance 3-piperidyl-1-(3’-methoxy-4’-hydroxyphenyl)-1-propanone 1-(4-hydroxy-3-methoxyphenyl)-3-(piperidin-1-yl)propan-1-one Not in list C15H21NO3 Oc1ccc(cc1OC)C(=O)CCN2CCCCC2 InChI=1/C15H21NO3/c1-19-15-11-12(5-6-14(15)18)13(17)7-10-16-8-3-2-4-9-16/h5-6,11,18H,2-4,7-10H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA1531 Not reported no data with Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is a metabolite of the substance 3-pyrrolidinyl-1-(3’-methoxy-4’-hydroxyphenyl)-1-propanone 1-(4-hydroxy-3-methoxyphenyl)-3-(pyrrolidin-1-yl)propan-1-one Not in list C14H19NO3 O=C(CCN1CCCC1)c2ccc(O)c(OC)c2 InChI=1S/C14H19NO3/c1-18-14-10-11(4-5-13(14)17)12(16)6-9-15-7-2-3-8-15/h4-5,10,17H,2-3,6-9H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA1964 Not reported no data with Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA1532 Not reported no data without Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is a metabolite of the substance 3-pyrrolidinyl-1-(3’-methoxy-4’-hydroxyphenyl)-1-propanone 1-(4-hydroxy-3-methoxyphenyl)-3-(pyrrolidin-1-yl)propan-1-one Not in list C14H19NO3 O=C(CCN1CCCC1)c2ccc(O)c(OC)c2 InChI=1S/C14H19NO3/c1-18-14-10-11(4-5-13(14)17)12(16)6-9-15-7-2-3-8-15/h4-5,10,17H,2-3,6-9H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA1531 Not reported no data with Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA1964 Not reported no data without Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is a metabolite of the substance 3-pyrrolidinyl-1-(3’-methoxy-4’-hydroxyphenyl)-1-propanone 1-(4-hydroxy-3-methoxyphenyl)-3-(pyrrolidin-1-yl)propan-1-one Not in list C14H19NO3 O=C(CCN1CCCC1)c2ccc(O)c(OC)c2 InChI=1S/C14H19NO3/c1-18-14-10-11(4-5-13(14)17)12(16)6-9-15-7-2-3-8-15/h4-5,10,17H,2-3,6-9H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA1532 Not reported no data without Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is a metabolite of the substance 3-piperidyl-1-(3’-methoxy-4’-hydroxyphenyl)-1-propanone 1-(4-hydroxy-3-methoxyphenyl)-3-(piperidin-1-yl)propan-1-one Not in list C15H21NO3 Oc1ccc(cc1OC)C(=O)CCN2CCCCC2 InChI=1/C15H21NO3/c1-19-15-11-12(5-6-14(15)18)13(17)7-10-16-8-3-2-4-9-16/h5-6,11,18H,2-4,7-10H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA1532 Not reported no data with Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is a metabolite of the substance 3-piperidyl-1-(3’-methoxy-4’-hydroxyphenyl)-1-propanone 1-(4-hydroxy-3-methoxyphenyl)-3-(piperidin-1-yl)propan-1-one Not in list C15H21NO3 Oc1ccc(cc1OC)C(=O)CCN2CCCCC2 InChI=1/C15H21NO3/c1-19-15-11-12(5-6-14(15)18)13(17)7-10-16-8-3-2-4-9-16/h5-6,11,18H,2-4,7-10H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA1530 Not reported no data without Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is a metabolite of the substance 3-piperidyl-1-(3’-methoxy-4’-hydroxyphenyl)-1-propanone 1-(4-hydroxy-3-methoxyphenyl)-3-(piperidin-1-yl)propan-1-one Not in list C15H21NO3 Oc1ccc(cc1OC)C(=O)CCN2CCCCC2 InChI=1/C15H21NO3/c1-19-15-11-12(5-6-14(15)18)13(17)7-10-16-8-3-2-4-9-16/h5-6,11,18H,2-4,7-10H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA1532 Not reported no data without Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is a metabolite of the substance 3-piperidyl-1-(3’-methoxy-4’-hydroxyphenyl)-1-propanone 1-(4-hydroxy-3-methoxyphenyl)-3-(piperidin-1-yl)propan-1-one Not in list C15H21NO3 Oc1ccc(cc1OC)C(=O)CCN2CCCCC2 InChI=1/C15H21NO3/c1-19-15-11-12(5-6-14(15)18)13(17)7-10-16-8-3-2-4-9-16/h5-6,11,18H,2-4,7-10H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA1964 Not reported no data without Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is a metabolite of the substance 3-piperidyl-1-(3’-methoxy-4’-hydroxyphenyl)-1-propanone 1-(4-hydroxy-3-methoxyphenyl)-3-(piperidin-1-yl)propan-1-one Not in list C15H21NO3 Oc1ccc(cc1OC)C(=O)CCN2CCCCC2 InChI=1/C15H21NO3/c1-19-15-11-12(5-6-14(15)18)13(17)7-10-16-8-3-2-4-9-16/h5-6,11,18H,2-4,7-10H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA1531 Not reported no data without Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is a metabolite of the substance 3-pyrrolidinyl-1-(3’-methoxy-4’-hydroxyphenyl)-1-propanone 1-(4-hydroxy-3-methoxyphenyl)-3-(pyrrolidin-1-yl)propan-1-one Not in list C14H19NO3 O=C(CCN1CCCC1)c2ccc(O)c(OC)c2 InChI=1S/C14H19NO3/c1-18-14-10-11(4-5-13(14)17)12(16)6-9-15-7-2-3-8-15/h4-5,10,17H,2-3,6-9H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA1530 Not reported no data without Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA1530 Not reported no data without Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is a metabolite of the substance 3-pyrrolidinyl-1-(3’-methoxy-4’-hydroxyphenyl)-1-propanone 1-(4-hydroxy-3-methoxyphenyl)-3-(pyrrolidin-1-yl)propan-1-one Not in list C14H19NO3 O=C(CCN1CCCC1)c2ccc(O)c(OC)c2 InChI=1S/C14H19NO3/c1-18-14-10-11(4-5-13(14)17)12(16)6-9-15-7-2-3-8-15/h4-5,10,17H,2-3,6-9H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA1531 Not reported no data without Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is a metabolite of the substance 3-pyrrolidinyl-1-(3’-methoxy-4’-hydroxyphenyl)-1-propanone 1-(4-hydroxy-3-methoxyphenyl)-3-(pyrrolidin-1-yl)propan-1-one Not in list C14H19NO3 O=C(CCN1CCCC1)c2ccc(O)c(OC)c2 InChI=1S/C14H19NO3/c1-18-14-10-11(4-5-13(14)17)12(16)6-9-15-7-2-3-8-15/h4-5,10,17H,2-3,6-9H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA1530 Not reported no data with Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is a metabolite of the substance 3-piperidyl-1-(3’-methoxy-4’-hydroxyphenyl)-1-propanone 1-(4-hydroxy-3-methoxyphenyl)-3-(piperidin-1-yl)propan-1-one Not in list C15H21NO3 Oc1ccc(cc1OC)C(=O)CCN2CCCCC2 InChI=1/C15H21NO3/c1-19-15-11-12(5-6-14(15)18)13(17)7-10-16-8-3-2-4-9-16/h5-6,11,18H,2-4,7-10H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA1964 Not reported no data with Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is a metabolite of the substance 3-pyrrolidinyl-1-(3’-methoxy-4’-hydroxyphenyl)-1-propanone 1-(4-hydroxy-3-methoxyphenyl)-3-(pyrrolidin-1-yl)propan-1-one Not in list C14H19NO3 O=C(CCN1CCCC1)c2ccc(O)c(OC)c2 InChI=1S/C14H19NO3/c1-18-14-10-11(4-5-13(14)17)12(16)6-9-15-7-2-3-8-15/h4-5,10,17H,2-3,6-9H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA1532 Not reported no data with Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is a metabolite of the substance 3-pyrrolidinyl-1-(3’-methoxy-4’-hydroxyphenyl)-1-propanone 1-(4-hydroxy-3-methoxyphenyl)-3-(pyrrolidin-1-yl)propan-1-one Not in list C14H19NO3 O=C(CCN1CCCC1)c2ccc(O)c(OC)c2 InChI=1S/C14H19NO3/c1-18-14-10-11(4-5-13(14)17)12(16)6-9-15-7-2-3-8-15/h4-5,10,17H,2-3,6-9H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA1964 Not reported no data without Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA1964 Not reported no data with Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA1531 Not reported no data with Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA1531 Not reported no data without Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA1532 Not reported no data with Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Geraniol 269-750-6 106-24-1 single chemical entity Component is identical to the substance Geraniol 269-750-6 106-24-1 (2E)-3,7-dimethylocta-2,6-dien-1-ol geraniol C10H18O CC(=CCCC(=CCO)C)C InChI=1S/C10H18O/c1-9(2)5-4-6-10(3)7-8-11/h5,7,11H,4,6,8H2,1-3H3/b10-7+ organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: The United Kingdom Geraniol 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance geraniol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2915
+Geraniol 269-750-6 106-24-1 single chemical entity Component is identical to the substance Geraniol 269-750-6 106-24-1 (2E)-3,7-dimethylocta-2,6-dien-1-ol geraniol C10H18O CC(=CCCC(=CCO)C)C InChI=1S/C10H18O/c1-9(2)5-4-6-10(3)7-8-11/h5,7,11H,4,6,8H2,1-3H3/b10-7+ organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: The United Kingdom Geraniol 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance geraniol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2915
+Geraniol 269-750-6 106-24-1 single chemical entity Component is identical to the substance Geraniol 269-750-6 106-24-1 (2E)-3,7-dimethylocta-2,6-dien-1-ol geraniol C10H18O CC(=CCCC(=CCO)C)C InChI=1S/C10H18O/c1-9(2)5-4-6-10(3)7-8-11/h5,7,11H,4,6,8H2,1-3H3/b10-7+ organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: The United Kingdom Geraniol 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance geraniol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2915
+Geraniol 269-750-6 106-24-1 single chemical entity Component is identical to the substance Geraniol 269-750-6 106-24-1 (2E)-3,7-dimethylocta-2,6-dien-1-ol geraniol C10H18O CC(=CCCC(=CCO)C)C InChI=1S/C10H18O/c1-9(2)5-4-6-10(3)7-8-11/h5,7,11H,4,6,8H2,1-3H3/b10-7+ organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: The United Kingdom Geraniol 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance geraniol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2915
+Geraniol 269-750-6 106-24-1 single chemical entity Component is identical to the substance Geraniol 269-750-6 106-24-1 (2E)-3,7-dimethylocta-2,6-dien-1-ol geraniol C10H18O CC(=CCCC(=CCO)C)C InChI=1S/C10H18O/c1-9(2)5-4-6-10(3)7-8-11/h5,7,11H,4,6,8H2,1-3H3/b10-7+ organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: The United Kingdom Geraniol 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance geraniol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2915
+Geraniol 269-750-6 106-24-1 single chemical entity Component is identical to the substance Geraniol 269-750-6 106-24-1 (2E)-3,7-dimethylocta-2,6-dien-1-ol geraniol C10H18O CC(=CCCC(=CCO)C)C InChI=1S/C10H18O/c1-9(2)5-4-6-10(3)7-8-11/h5,7,11H,4,6,8H2,1-3H3/b10-7+ organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: The United Kingdom Geraniol 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance geraniol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2915
+Geraniol 269-750-6 106-24-1 single chemical entity Component is identical to the substance Geraniol 269-750-6 106-24-1 (2E)-3,7-dimethylocta-2,6-dien-1-ol geraniol C10H18O CC(=CCCC(=CCO)C)C InChI=1S/C10H18O/c1-9(2)5-4-6-10(3)7-8-11/h5,7,11H,4,6,8H2,1-3H3/b10-7+ organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: The United Kingdom Geraniol 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance geraniol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2915
+Geraniol 269-750-6 106-24-1 single chemical entity Component is identical to the substance Geraniol 269-750-6 106-24-1 (2E)-3,7-dimethylocta-2,6-dien-1-ol geraniol C10H18O CC(=CCCC(=CCO)C)C InChI=1S/C10H18O/c1-9(2)5-4-6-10(3)7-8-11/h5,7,11H,4,6,8H2,1-3H3/b10-7+ organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: The United Kingdom Geraniol 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance geraniol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2915
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported no data without Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported no data with Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes with Positive RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes without Positive RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) Yes Acceptable Hamster (as animal) CHO Not reported no data with Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported no data with Positive RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) Yes Acceptable Hamster (as animal) CHO Not reported no data without Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported no data without Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Positive RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Positive RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) embryo cells Not reported yes without Positive RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) embryo cells Not reported yes with Positive RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) Yes Acceptable Human (as organism) lymphocytes Not reported yes without Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) Yes Acceptable Human (as organism) lymphocytes Not reported yes with Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Positive small colonies RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Human (as organism) leukemia cells (HL-60) Not reported no data without Positive RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) ddy mouse 6 Male Not reported 18.0000000000 h yes not applicable Negative direct evidence-cytotoxicity RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) ddy mouse 6 Male Not reported 24.0000000000 h yes not applicable Negative direct evidence-cytotoxicity RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) SwissWebster Male intraperitoneal no data not applicable Positive no evidence RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) SwissWebster Male oral: gavage no data not applicable Positive no evidence RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Swiss 5 Male intraperitoneal 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CF-1 8 Male intraperitoneal 30.0000000000 h yes not applicable Positive no evidence RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CF-1 8 Male intraperitoneal 48.0000000000 h yes not applicable Positive no evidence RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CF-1 8 Male intraperitoneal 24.0000000000 h yes not applicable Positive no evidence RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo According to OECD Guideline 489 No Acceptable Rat (as animal) Sprague-Dawley 4 Female oral: gavage 30.0000000000 h no data not applicable Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo According to OECD Guideline 489 No Acceptable Rat (as animal) Sprague-Dawley 4 Female oral: gavage 48.0000000000 h no data not applicable Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo According to OECD Guideline 489 No Acceptable Rat (as animal) Sprague-Dawley 4 Female oral: gavage 6.0000000000 h no data not applicable Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo According to OECD Guideline 489 No Acceptable Rat (as animal) Sprague-Dawley 4 Female oral: gavage 48.0000000000 h no data not applicable Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo According to OECD Guideline 489 No Acceptable Rat (as animal) Sprague-Dawley 4 Female oral: gavage 2.0000000000 h no data not applicable Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo According to OECD Guideline 489 No Acceptable Rat (as animal) Sprague-Dawley 4 Female oral: gavage 2.0000000000 h no data not applicable Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo According to OECD Guideline 489 No Acceptable Rat (as animal) Sprague-Dawley 4 Female oral: gavage 24.0000000000 h no data not applicable Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo According to OECD Guideline 489 No Acceptable Rat (as animal) Sprague-Dawley 4 Female oral: gavage 30.0000000000 h no data not applicable Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo According to OECD Guideline 489 No Acceptable Rat (as animal) Sprague-Dawley 4 Female oral: gavage 6.0000000000 h no data not applicable Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo According to OECD Guideline 489 No Acceptable Rat (as animal) Sprague-Dawley 4 Female oral: gavage 24.0000000000 h no data not applicable Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) 4 Male oral: feed 58.0000000000 D yes not applicable Ambiguous RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) 4 Male oral: feed 58.0000000000 D yes not applicable Ambiguous RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable Rat (as animal) Wistar Male oral: gavage 10.0000000000 D yes not applicable Negative no evidence RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo Equivalent or similar to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No data Acceptable Rat (as animal) Wistar Male oral: gavage 10.0000000000 D no data not applicable Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable Human (as organism) No data oral: capsule 22.0000000000 D no data not applicable Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No data Acceptable Human (as organism) No data oral: capsule 22.0000000000 D no data not applicable Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable Human (as organism) No data oral: capsule 8.0000000000 D no data not applicable Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No data Acceptable Human (as organism) No data oral: capsule 8.0000000000 D no data not applicable Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Eugenol 202-589-1 97-53-0 single chemical entity Component is identical to the substance Eugenol 202-589-1 97-53-0 2-Methoxy-4-prop-2-enylphenol Not in list C10H12O2 COC1=C(C=CC(=C1)CC=C)O InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) Not reported No data intraperitoneal no data not applicable Negative RMS: The United Kingdom Eugenol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2914
+Chlorantraniliprole 500008-45-7 single chemical entity Component is identical to the substance Chlorantraniliprole 500008-45-7 3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Chlorantraniliprole (DPX E-2Y45) C18H14BrCl2N5O2 CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is identical to the substance Chlorantraniliprole 500008-45-7 3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Chlorantraniliprole (DPX E-2Y45) C18H14BrCl2N5O2 CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is identical to the substance Chlorantraniliprole 500008-45-7 3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Chlorantraniliprole (DPX E-2Y45) C18H14BrCl2N5O2 CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is identical to the substance Chlorantraniliprole 500008-45-7 3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Chlorantraniliprole (DPX E-2Y45) C18H14BrCl2N5O2 CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is identical to the substance Chlorantraniliprole 500008-45-7 3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Chlorantraniliprole (DPX E-2Y45) C18H14BrCl2N5O2 CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is identical to the substance Chlorantraniliprole 500008-45-7 3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Chlorantraniliprole (DPX E-2Y45) C18H14BrCl2N5O2 CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is identical to the substance Chlorantraniliprole 500008-45-7 3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Chlorantraniliprole (DPX E-2Y45) C18H14BrCl2N5O2 CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is identical to the substance Chlorantraniliprole 500008-45-7 3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Chlorantraniliprole (DPX E-2Y45) C18H14BrCl2N5O2 CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is identical to the substance Chlorantraniliprole 500008-45-7 3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Chlorantraniliprole (DPX E-2Y45) C18H14BrCl2N5O2 CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is identical to the substance Chlorantraniliprole 500008-45-7 3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Chlorantraniliprole (DPX E-2Y45) C18H14BrCl2N5O2 CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is identical to the substance Chlorantraniliprole 500008-45-7 3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Chlorantraniliprole (DPX E-2Y45) C18H14BrCl2N5O2 CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is identical to the substance Chlorantraniliprole 500008-45-7 3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Chlorantraniliprole (DPX E-2Y45) C18H14BrCl2N5O2 CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is identical to the substance Chlorantraniliprole 500008-45-7 3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Chlorantraniliprole (DPX E-2Y45) C18H14BrCl2N5O2 CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is identical to the substance Chlorantraniliprole 500008-45-7 3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Chlorantraniliprole (DPX E-2Y45) C18H14BrCl2N5O2 CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is identical to the substance Chlorantraniliprole 500008-45-7 3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Chlorantraniliprole (DPX E-2Y45) C18H14BrCl2N5O2 CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is identical to the substance Chlorantraniliprole 500008-45-7 3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Chlorantraniliprole (DPX E-2Y45) C18H14BrCl2N5O2 CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is identical to the substance Chlorantraniliprole 500008-45-7 3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Chlorantraniliprole (DPX E-2Y45) C18H14BrCl2N5O2 CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is identical to the substance Chlorantraniliprole 500008-45-7 3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Chlorantraniliprole (DPX E-2Y45) C18H14BrCl2N5O2 CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is identical to the substance Chlorantraniliprole 500008-45-7 3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Chlorantraniliprole (DPX E-2Y45) C18H14BrCl2N5O2 CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is identical to the substance Chlorantraniliprole 500008-45-7 3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Chlorantraniliprole (DPX E-2Y45) C18H14BrCl2N5O2 CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is identical to the substance Chlorantraniliprole 500008-45-7 3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Chlorantraniliprole (DPX E-2Y45) C18H14BrCl2N5O2 CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is identical to the substance Chlorantraniliprole 500008-45-7 3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Chlorantraniliprole (DPX E-2Y45) C18H14BrCl2N5O2 CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is identical to the substance Chlorantraniliprole 500008-45-7 3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Chlorantraniliprole (DPX E-2Y45) C18H14BrCl2N5O2 CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is identical to the substance Chlorantraniliprole 500008-45-7 3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Chlorantraniliprole (DPX E-2Y45) C18H14BrCl2N5O2 CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is identical to the substance Chlorantraniliprole 500008-45-7 3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Chlorantraniliprole (DPX E-2Y45) C18H14BrCl2N5O2 CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is identical to the substance Chlorantraniliprole 500008-45-7 3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Chlorantraniliprole (DPX E-2Y45) C18H14BrCl2N5O2 CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is identical to the substance Chlorantraniliprole 500008-45-7 3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Chlorantraniliprole (DPX E-2Y45) C18H14BrCl2N5O2 CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is identical to the substance Chlorantraniliprole 500008-45-7 3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide Chlorantraniliprole (DPX E-2Y45) C18H14BrCl2N5O2 CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is a metabolite of the substance 2-[3-bromo-1-(3-chloropyridin-2-yl)-1Hpyrazol-5-yl]-6-chloro-3,8-dimethylquinazolin-4(3H)-one 2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-6-chloro-3,8-dimethylquinazolin-4(3H)-one Not in list C18H12BrCl2N5O Cc4cc(Cl)cc3c4N=C(c2cc(Br)nn2c1ncccc1Cl)N(C)C3=O InChI=1/C18H12BrCl2N5O/c1-9-6-10(20)7-11-15(9)23-17(25(2)18(11)27)13-8-14(19)24-26(13)16-12(21)4-3-5-22-16/h3-8H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is a metabolite of the substance 2-[3-bromo-1-(3-chloropyridin-2-yl)-1Hpyrazol-5-yl]-6-chloro-3,8-dimethylquinazolin-4(3H)-one 2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-6-chloro-3,8-dimethylquinazolin-4(3H)-one Not in list C18H12BrCl2N5O Cc4cc(Cl)cc3c4N=C(c2cc(Br)nn2c1ncccc1Cl)N(C)C3=O InChI=1/C18H12BrCl2N5O/c1-9-6-10(20)7-11-15(9)23-17(25(2)18(11)27)13-8-14(19)24-26(13)16-12(21)4-3-5-22-16/h3-8H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is a metabolite of the substance 2-[3-bromo-1-(3-chloropyridin-2-yl)-1Hpyrazol-5-yl]-6-chloro-3,8-dimethylquinazolin-4(3H)-one 2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-6-chloro-3,8-dimethylquinazolin-4(3H)-one Not in list C18H12BrCl2N5O Cc4cc(Cl)cc3c4N=C(c2cc(Br)nn2c1ncccc1Cl)N(C)C3=O InChI=1/C18H12BrCl2N5O/c1-9-6-10(20)7-11-15(9)23-17(25(2)18(11)27)13-8-14(19)24-26(13)16-12(21)4-3-5-22-16/h3-8H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is a metabolite of the substance 2-[3-bromo-1-(3-chloropyridin-2-yl)-1Hpyrazol-5-yl]-6-chloro-3,8-dimethylquinazolin-4(3H)-one 2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-6-chloro-3,8-dimethylquinazolin-4(3H)-one Not in list C18H12BrCl2N5O Cc4cc(Cl)cc3c4N=C(c2cc(Br)nn2c1ncccc1Cl)N(C)C3=O InChI=1/C18H12BrCl2N5O/c1-9-6-10(20)7-11-15(9)23-17(25(2)18(11)27)13-8-14(19)24-26(13)16-12(21)4-3-5-22-16/h3-8H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is a metabolite of the substance 2-[3-bromo-1-(3-chloropyridin-2-yl)-1Hpyrazol-5-yl]-6-chloro-3,8-dimethylquinazolin-4(3H)-one 2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-6-chloro-3,8-dimethylquinazolin-4(3H)-one Not in list C18H12BrCl2N5O Cc4cc(Cl)cc3c4N=C(c2cc(Br)nn2c1ncccc1Cl)N(C)C3=O InChI=1/C18H12BrCl2N5O/c1-9-6-10(20)7-11-15(9)23-17(25(2)18(11)27)13-8-14(19)24-26(13)16-12(21)4-3-5-22-16/h3-8H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is a metabolite of the substance 2-[3-bromo-1-(3-chloropyridin-2-yl)-1Hpyrazol-5-yl]-6-chloro-3,8-dimethylquinazolin-4(3H)-one 2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-6-chloro-3,8-dimethylquinazolin-4(3H)-one Not in list C18H12BrCl2N5O Cc4cc(Cl)cc3c4N=C(c2cc(Br)nn2c1ncccc1Cl)N(C)C3=O InChI=1/C18H12BrCl2N5O/c1-9-6-10(20)7-11-15(9)23-17(25(2)18(11)27)13-8-14(19)24-26(13)16-12(21)4-3-5-22-16/h3-8H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is a metabolite of the substance 2-[3-bromo-1-(3-chloropyridin-2-yl)-1Hpyrazol-5-yl]-6-chloro-3,8-dimethylquinazolin-4(3H)-one 2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-6-chloro-3,8-dimethylquinazolin-4(3H)-one Not in list C18H12BrCl2N5O Cc4cc(Cl)cc3c4N=C(c2cc(Br)nn2c1ncccc1Cl)N(C)C3=O InChI=1/C18H12BrCl2N5O/c1-9-6-10(20)7-11-15(9)23-17(25(2)18(11)27)13-8-14(19)24-26(13)16-12(21)4-3-5-22-16/h3-8H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is a metabolite of the substance 2-[3-bromo-1-(3-chloropyridin-2-yl)-1Hpyrazol-5-yl]-6-chloro-3,8-dimethylquinazolin-4(3H)-one 2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-6-chloro-3,8-dimethylquinazolin-4(3H)-one Not in list C18H12BrCl2N5O Cc4cc(Cl)cc3c4N=C(c2cc(Br)nn2c1ncccc1Cl)N(C)C3=O InChI=1/C18H12BrCl2N5O/c1-9-6-10(20)7-11-15(9)23-17(25(2)18(11)27)13-8-14(19)24-26(13)16-12(21)4-3-5-22-16/h3-8H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is a metabolite of the substance 2-[3-bromo-1-(3-chloropyridin-2-yl)-1Hpyrazol-5-yl]-6-chloro-3,8-dimethylquinazolin-4(3H)-one 2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-6-chloro-3,8-dimethylquinazolin-4(3H)-one Not in list C18H12BrCl2N5O Cc4cc(Cl)cc3c4N=C(c2cc(Br)nn2c1ncccc1Cl)N(C)C3=O InChI=1/C18H12BrCl2N5O/c1-9-6-10(20)7-11-15(9)23-17(25(2)18(11)27)13-8-14(19)24-26(13)16-12(21)4-3-5-22-16/h3-8H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is a metabolite of the substance 2-[3-bromo-1-(3-chloropyridin-2-yl)-1Hpyrazol-5-yl]-6-chloro-3,8-dimethylquinazolin-4(3H)-one 2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-6-chloro-3,8-dimethylquinazolin-4(3H)-one Not in list C18H12BrCl2N5O Cc4cc(Cl)cc3c4N=C(c2cc(Br)nn2c1ncccc1Cl)N(C)C3=O InChI=1/C18H12BrCl2N5O/c1-9-6-10(20)7-11-15(9)23-17(25(2)18(11)27)13-8-14(19)24-26(13)16-12(21)4-3-5-22-16/h3-8H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is a metabolite of the substance 2-(3-bromo-1H-pyrazol-5-yl)-6-chloro-3,8-dimethylquinazolin-4(3H)-one 2-(3-bromo-1H-pyrazol-5-yl)-6-chloro-3,8-dimethylquinazolin-4(3H)-one Not in list C13H10BrClN4O Brc1cc(nn1)C2=Nc3c(C)cc(Cl)cc3C(=O)N2C InChI=1/C13H10BrClN4O/c1-6-3-7(15)4-8-11(6)16-12(19(2)13(8)20)9-5-10(14)18-17-9/h3-5H,1-2H3,(H,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is a metabolite of the substance 2-(3-bromo-1H-pyrazol-5-yl)-6-chloro-3,8-dimethylquinazolin-4(3H)-one 2-(3-bromo-1H-pyrazol-5-yl)-6-chloro-3,8-dimethylquinazolin-4(3H)-one Not in list C13H10BrClN4O Brc1cc(nn1)C2=Nc3c(C)cc(Cl)cc3C(=O)N2C InChI=1/C13H10BrClN4O/c1-6-3-7(15)4-8-11(6)16-12(19(2)13(8)20)9-5-10(14)18-17-9/h3-5H,1-2H3,(H,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is a metabolite of the substance 2-(3-bromo-1H-pyrazol-5-yl)-6-chloro-3,8-dimethylquinazolin-4(3H)-one 2-(3-bromo-1H-pyrazol-5-yl)-6-chloro-3,8-dimethylquinazolin-4(3H)-one Not in list C13H10BrClN4O Brc1cc(nn1)C2=Nc3c(C)cc(Cl)cc3C(=O)N2C InChI=1/C13H10BrClN4O/c1-6-3-7(15)4-8-11(6)16-12(19(2)13(8)20)9-5-10(14)18-17-9/h3-5H,1-2H3,(H,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is a metabolite of the substance 2-(3-bromo-1H-pyrazol-5-yl)-6-chloro-3,8-dimethylquinazolin-4(3H)-one 2-(3-bromo-1H-pyrazol-5-yl)-6-chloro-3,8-dimethylquinazolin-4(3H)-one Not in list C13H10BrClN4O Brc1cc(nn1)C2=Nc3c(C)cc(Cl)cc3C(=O)N2C InChI=1/C13H10BrClN4O/c1-6-3-7(15)4-8-11(6)16-12(19(2)13(8)20)9-5-10(14)18-17-9/h3-5H,1-2H3,(H,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is a metabolite of the substance 2-(3-bromo-1H-pyrazol-5-yl)-6-chloro-3,8-dimethylquinazolin-4(3H)-one 2-(3-bromo-1H-pyrazol-5-yl)-6-chloro-3,8-dimethylquinazolin-4(3H)-one Not in list C13H10BrClN4O Brc1cc(nn1)C2=Nc3c(C)cc(Cl)cc3C(=O)N2C InChI=1/C13H10BrClN4O/c1-6-3-7(15)4-8-11(6)16-12(19(2)13(8)20)9-5-10(14)18-17-9/h3-5H,1-2H3,(H,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is a metabolite of the substance 2-(3-bromo-1H-pyrazol-5-yl)-6-chloro-3,8-dimethylquinazolin-4(3H)-one 2-(3-bromo-1H-pyrazol-5-yl)-6-chloro-3,8-dimethylquinazolin-4(3H)-one Not in list C13H10BrClN4O Brc1cc(nn1)C2=Nc3c(C)cc(Cl)cc3C(=O)N2C InChI=1/C13H10BrClN4O/c1-6-3-7(15)4-8-11(6)16-12(19(2)13(8)20)9-5-10(14)18-17-9/h3-5H,1-2H3,(H,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is a metabolite of the substance 2-(3-bromo-1H-pyrazol-5-yl)-6-chloro-3,8-dimethylquinazolin-4(3H)-one 2-(3-bromo-1H-pyrazol-5-yl)-6-chloro-3,8-dimethylquinazolin-4(3H)-one Not in list C13H10BrClN4O Brc1cc(nn1)C2=Nc3c(C)cc(Cl)cc3C(=O)N2C InChI=1/C13H10BrClN4O/c1-6-3-7(15)4-8-11(6)16-12(19(2)13(8)20)9-5-10(14)18-17-9/h3-5H,1-2H3,(H,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is a metabolite of the substance 2-(3-bromo-1H-pyrazol-5-yl)-6-chloro-3,8-dimethylquinazolin-4(3H)-one 2-(3-bromo-1H-pyrazol-5-yl)-6-chloro-3,8-dimethylquinazolin-4(3H)-one Not in list C13H10BrClN4O Brc1cc(nn1)C2=Nc3c(C)cc(Cl)cc3C(=O)N2C InChI=1/C13H10BrClN4O/c1-6-3-7(15)4-8-11(6)16-12(19(2)13(8)20)9-5-10(14)18-17-9/h3-5H,1-2H3,(H,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is a metabolite of the substance 2-(3-bromo-1H-pyrazol-5-yl)-6-chloro-3,8-dimethylquinazolin-4(3H)-one 2-(3-bromo-1H-pyrazol-5-yl)-6-chloro-3,8-dimethylquinazolin-4(3H)-one Not in list C13H10BrClN4O Brc1cc(nn1)C2=Nc3c(C)cc(Cl)cc3C(=O)N2C InChI=1/C13H10BrClN4O/c1-6-3-7(15)4-8-11(6)16-12(19(2)13(8)20)9-5-10(14)18-17-9/h3-5H,1-2H3,(H,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is a metabolite of the substance 2-(3-bromo-1H-pyrazol-5-yl)-6-chloro-3,8-dimethylquinazolin-4(3H)-one 2-(3-bromo-1H-pyrazol-5-yl)-6-chloro-3,8-dimethylquinazolin-4(3H)-one Not in list C13H10BrClN4O Brc1cc(nn1)C2=Nc3c(C)cc(Cl)cc3C(=O)N2C InChI=1/C13H10BrClN4O/c1-6-3-7(15)4-8-11(6)16-12(19(2)13(8)20)9-5-10(14)18-17-9/h3-5H,1-2H3,(H,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is a metabolite of the substance 2,6-dichloro-4-methyl-11H-pyrido[2,1-b]quinazolin-11-one 2,6-dichloro-4-methyl-11H-pyrido[2,1-b]quinazolin-11-one Not in list C13H8Cl2N2O Cc3cc(Cl)cc2c3N=C1C(Cl)=CC=CN1C2=O InChI=1/C13H8Cl2N2O/c1-7-5-8(14)6-9-11(7)16-12-10(15)3-2-4-17(12)13(9)18/h2-6H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is a metabolite of the substance 2,6-dichloro-4-methyl-11H-pyrido[2,1-b]quinazolin-11-one 2,6-dichloro-4-methyl-11H-pyrido[2,1-b]quinazolin-11-one Not in list C13H8Cl2N2O Cc3cc(Cl)cc2c3N=C1C(Cl)=CC=CN1C2=O InChI=1/C13H8Cl2N2O/c1-7-5-8(14)6-9-11(7)16-12-10(15)3-2-4-17(12)13(9)18/h2-6H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is a metabolite of the substance 2,6-dichloro-4-methyl-11H-pyrido[2,1-b]quinazolin-11-one 2,6-dichloro-4-methyl-11H-pyrido[2,1-b]quinazolin-11-one Not in list C13H8Cl2N2O Cc3cc(Cl)cc2c3N=C1C(Cl)=CC=CN1C2=O InChI=1/C13H8Cl2N2O/c1-7-5-8(14)6-9-11(7)16-12-10(15)3-2-4-17(12)13(9)18/h2-6H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is a metabolite of the substance 2,6-dichloro-4-methyl-11H-pyrido[2,1-b]quinazolin-11-one 2,6-dichloro-4-methyl-11H-pyrido[2,1-b]quinazolin-11-one Not in list C13H8Cl2N2O Cc3cc(Cl)cc2c3N=C1C(Cl)=CC=CN1C2=O InChI=1/C13H8Cl2N2O/c1-7-5-8(14)6-9-11(7)16-12-10(15)3-2-4-17(12)13(9)18/h2-6H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is a metabolite of the substance 2,6-dichloro-4-methyl-11H-pyrido[2,1-b]quinazolin-11-one 2,6-dichloro-4-methyl-11H-pyrido[2,1-b]quinazolin-11-one Not in list C13H8Cl2N2O Cc3cc(Cl)cc2c3N=C1C(Cl)=CC=CN1C2=O InChI=1/C13H8Cl2N2O/c1-7-5-8(14)6-9-11(7)16-12-10(15)3-2-4-17(12)13(9)18/h2-6H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is a metabolite of the substance 2,6-dichloro-4-methyl-11H-pyrido[2,1-b]quinazolin-11-one 2,6-dichloro-4-methyl-11H-pyrido[2,1-b]quinazolin-11-one Not in list C13H8Cl2N2O Cc3cc(Cl)cc2c3N=C1C(Cl)=CC=CN1C2=O InChI=1/C13H8Cl2N2O/c1-7-5-8(14)6-9-11(7)16-12-10(15)3-2-4-17(12)13(9)18/h2-6H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is a metabolite of the substance 2,6-dichloro-4-methyl-11H-pyrido[2,1-b]quinazolin-11-one 2,6-dichloro-4-methyl-11H-pyrido[2,1-b]quinazolin-11-one Not in list C13H8Cl2N2O Cc3cc(Cl)cc2c3N=C1C(Cl)=CC=CN1C2=O InChI=1/C13H8Cl2N2O/c1-7-5-8(14)6-9-11(7)16-12-10(15)3-2-4-17(12)13(9)18/h2-6H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is a metabolite of the substance 2,6-dichloro-4-methyl-11H-pyrido[2,1-b]quinazolin-11-one 2,6-dichloro-4-methyl-11H-pyrido[2,1-b]quinazolin-11-one Not in list C13H8Cl2N2O Cc3cc(Cl)cc2c3N=C1C(Cl)=CC=CN1C2=O InChI=1/C13H8Cl2N2O/c1-7-5-8(14)6-9-11(7)16-12-10(15)3-2-4-17(12)13(9)18/h2-6H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is a metabolite of the substance 2,6-dichloro-4-methyl-11H-pyrido[2,1-b]quinazolin-11-one 2,6-dichloro-4-methyl-11H-pyrido[2,1-b]quinazolin-11-one Not in list C13H8Cl2N2O Cc3cc(Cl)cc2c3N=C1C(Cl)=CC=CN1C2=O InChI=1/C13H8Cl2N2O/c1-7-5-8(14)6-9-11(7)16-12-10(15)3-2-4-17(12)13(9)18/h2-6H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is a metabolite of the substance 2,6-dichloro-4-methyl-11H-pyrido[2,1-b]quinazolin-11-one 2,6-dichloro-4-methyl-11H-pyrido[2,1-b]quinazolin-11-one Not in list C13H8Cl2N2O Cc3cc(Cl)cc2c3N=C1C(Cl)=CC=CN1C2=O InChI=1/C13H8Cl2N2O/c1-7-5-8(14)6-9-11(7)16-12-10(15)3-2-4-17(12)13(9)18/h2-6H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is a metabolite of the substance 3-bromo-N-methyl-1H-pyrazole-5-carboxamide 3-bromo-N-methyl-1H-pyrazole-5-carboxamide Not in list C5H6BrN3O O=C(NC)c1cc(Br)nn1 InChI=1/C5H6BrN3O/c1-7-5(10)3-2-4(6)9-8-3/h2H,1H3,(H,7,10)(H,8,9) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is a metabolite of the substance 3-bromo-N-methyl-1H-pyrazole-5-carboxamide 3-bromo-N-methyl-1H-pyrazole-5-carboxamide Not in list C5H6BrN3O O=C(NC)c1cc(Br)nn1 InChI=1/C5H6BrN3O/c1-7-5(10)3-2-4(6)9-8-3/h2H,1H3,(H,7,10)(H,8,9) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is a metabolite of the substance 3-bromo-N-methyl-1H-pyrazole-5-carboxamide 3-bromo-N-methyl-1H-pyrazole-5-carboxamide Not in list C5H6BrN3O O=C(NC)c1cc(Br)nn1 InChI=1/C5H6BrN3O/c1-7-5(10)3-2-4(6)9-8-3/h2H,1H3,(H,7,10)(H,8,9) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is a metabolite of the substance 3-bromo-N-methyl-1H-pyrazole-5-carboxamide 3-bromo-N-methyl-1H-pyrazole-5-carboxamide Not in list C5H6BrN3O O=C(NC)c1cc(Br)nn1 InChI=1/C5H6BrN3O/c1-7-5(10)3-2-4(6)9-8-3/h2H,1H3,(H,7,10)(H,8,9) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is a metabolite of the substance 3-bromo-N-methyl-1H-pyrazole-5-carboxamide 3-bromo-N-methyl-1H-pyrazole-5-carboxamide Not in list C5H6BrN3O O=C(NC)c1cc(Br)nn1 InChI=1/C5H6BrN3O/c1-7-5(10)3-2-4(6)9-8-3/h2H,1H3,(H,7,10)(H,8,9) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is a metabolite of the substance 3-bromo-N-methyl-1H-pyrazole-5-carboxamide 3-bromo-N-methyl-1H-pyrazole-5-carboxamide Not in list C5H6BrN3O O=C(NC)c1cc(Br)nn1 InChI=1/C5H6BrN3O/c1-7-5(10)3-2-4(6)9-8-3/h2H,1H3,(H,7,10)(H,8,9) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is a metabolite of the substance 3-bromo-N-methyl-1H-pyrazole-5-carboxamide 3-bromo-N-methyl-1H-pyrazole-5-carboxamide Not in list C5H6BrN3O O=C(NC)c1cc(Br)nn1 InChI=1/C5H6BrN3O/c1-7-5(10)3-2-4(6)9-8-3/h2H,1H3,(H,7,10)(H,8,9) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is a metabolite of the substance 3-bromo-N-methyl-1H-pyrazole-5-carboxamide 3-bromo-N-methyl-1H-pyrazole-5-carboxamide Not in list C5H6BrN3O O=C(NC)c1cc(Br)nn1 InChI=1/C5H6BrN3O/c1-7-5(10)3-2-4(6)9-8-3/h2H,1H3,(H,7,10)(H,8,9) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is a metabolite of the substance 3-bromo-N-methyl-1H-pyrazole-5-carboxamide 3-bromo-N-methyl-1H-pyrazole-5-carboxamide Not in list C5H6BrN3O O=C(NC)c1cc(Br)nn1 InChI=1/C5H6BrN3O/c1-7-5(10)3-2-4(6)9-8-3/h2H,1H3,(H,7,10)(H,8,9) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Chlorantraniliprole 500008-45-7 single chemical entity Component is a metabolite of the substance 3-bromo-N-methyl-1H-pyrazole-5-carboxamide 3-bromo-N-methyl-1H-pyrazole-5-carboxamide Not in list C5H6BrN3O O=C(NC)c1cc(Br)nn1 InChI=1/C5H6BrN3O/c1-7-5(10)3-2-4(6)9-8-3/h2H,1H3,(H,7,10)(H,8,9) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Ireland Chlorantraniliprole 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole. 06Jun2013 2013 doi:10.2903/j.efsa.2013.3143
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is identical to the substance Carbosulfan 259-565-9 55285-14-8 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate Carbosulfan C20H32N2O3S CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is identical to the substance Carbosulfan 259-565-9 55285-14-8 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate Carbosulfan C20H32N2O3S CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is identical to the substance Carbosulfan 259-565-9 55285-14-8 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate Carbosulfan C20H32N2O3S CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is identical to the substance Carbosulfan 259-565-9 55285-14-8 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate Carbosulfan C20H32N2O3S CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is identical to the substance Carbosulfan 259-565-9 55285-14-8 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate Carbosulfan C20H32N2O3S CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is identical to the substance Carbosulfan 259-565-9 55285-14-8 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate Carbosulfan C20H32N2O3S CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is identical to the substance Carbosulfan 259-565-9 55285-14-8 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate Carbosulfan C20H32N2O3S CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is identical to the substance Carbosulfan 259-565-9 55285-14-8 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate Carbosulfan C20H32N2O3S CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is identical to the substance Carbosulfan 259-565-9 55285-14-8 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate Carbosulfan C20H32N2O3S CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is identical to the substance Carbosulfan 259-565-9 55285-14-8 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate Carbosulfan C20H32N2O3S CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is identical to the substance Carbosulfan 259-565-9 55285-14-8 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate Carbosulfan C20H32N2O3S CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is identical to the substance Carbosulfan 259-565-9 55285-14-8 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate Carbosulfan C20H32N2O3S CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is identical to the substance Carbosulfan 259-565-9 55285-14-8 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate Carbosulfan C20H32N2O3S CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is identical to the substance Carbosulfan 259-565-9 55285-14-8 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate Carbosulfan C20H32N2O3S CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is identical to the substance Carbosulfan 259-565-9 55285-14-8 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate Carbosulfan C20H32N2O3S CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is identical to the substance Carbosulfan 259-565-9 55285-14-8 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate Carbosulfan C20H32N2O3S CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is identical to the substance Carbosulfan 259-565-9 55285-14-8 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate Carbosulfan C20H32N2O3S CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is identical to the substance Carbosulfan 259-565-9 55285-14-8 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate Carbosulfan C20H32N2O3S CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is identical to the substance Carbosulfan 259-565-9 55285-14-8 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate Carbosulfan C20H32N2O3S CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is identical to the substance Carbosulfan 259-565-9 55285-14-8 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate Carbosulfan C20H32N2O3S CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is identical to the substance Carbosulfan 259-565-9 55285-14-8 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate Carbosulfan C20H32N2O3S CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3 organic compound Other Other DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is identical to the substance Carbosulfan 259-565-9 55285-14-8 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate Carbosulfan C20H32N2O3S CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3 organic compound Other Other DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Salmonella typhimurium (as organism) TA1978 Not reported yes without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is identical to the substance Carbosulfan 259-565-9 55285-14-8 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate Carbosulfan C20H32N2O3S CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3 organic compound Other Other DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is identical to the substance Carbosulfan 259-565-9 55285-14-8 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate Carbosulfan C20H32N2O3S CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3 organic compound Other Other DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) WP100 Not reported yes without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is identical to the substance Carbosulfan 259-565-9 55285-14-8 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate Carbosulfan C20H32N2O3S CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3 organic compound Other Other DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Salmonella typhimurium (as organism) TA1978 Not reported yes with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is identical to the substance Carbosulfan 259-565-9 55285-14-8 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate Carbosulfan C20H32N2O3S CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3 organic compound Other Other DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is identical to the substance Carbosulfan 259-565-9 55285-14-8 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate Carbosulfan C20H32N2O3S CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3 organic compound Other Other DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) WP100 Not reported yes with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is identical to the substance Carbosulfan 259-565-9 55285-14-8 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate Carbosulfan C20H32N2O3S CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3 organic compound Other Other DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is identical to the substance Carbosulfan 259-565-9 55285-14-8 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate Carbosulfan C20H32N2O3S CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is identical to the substance Carbosulfan 259-565-9 55285-14-8 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate Carbosulfan C20H32N2O3S CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is identical to the substance Carbosulfan 259-565-9 55285-14-8 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate Carbosulfan C20H32N2O3S CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data with Negative no information RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is identical to the substance Carbosulfan 259-565-9 55285-14-8 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate Carbosulfan C20H32N2O3S CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data without Negative no information RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is identical to the substance Carbosulfan 259-565-9 55285-14-8 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate Carbosulfan C20H32N2O3S CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is identical to the substance Carbosulfan 259-565-9 55285-14-8 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate Carbosulfan C20H32N2O3S CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is identical to the substance Carbosulfan 259-565-9 55285-14-8 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate Carbosulfan C20H32N2O3S CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3 organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Human (as organism) HeLa cells Not reported yes, concurrent vehicle with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is identical to the substance Carbosulfan 259-565-9 55285-14-8 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate Carbosulfan C20H32N2O3S CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3 organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Human (as organism) HeLa cells Not reported yes, concurrent vehicle without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is identical to the substance Carbosulfan 259-565-9 55285-14-8 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate Carbosulfan C20H32N2O3S CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Swiss 10 Male oral: unspecified 72.0000000000 h yes, concurrent vehicle not applicable Inconclusive indirect evidence-systemic toxicity RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is identical to the substance Carbosulfan 259-565-9 55285-14-8 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate Carbosulfan C20H32N2O3S CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Swiss 10 Male oral: unspecified 48.0000000000 h yes, concurrent vehicle not applicable Inconclusive indirect evidence-systemic toxicity RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is identical to the substance Carbosulfan 259-565-9 55285-14-8 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate Carbosulfan C20H32N2O3S CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Swiss 10 Male oral: unspecified 96.0000000000 h yes, concurrent vehicle not applicable Inconclusive indirect evidence-systemic toxicity RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is identical to the substance Carbosulfan 259-565-9 55285-14-8 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate Carbosulfan C20H32N2O3S CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3 organic compound Other Other chromosome aberration other in vitro No guideline available Not reported Not applicable Acceptable Saccharomyces cerevisiae (as organism) D7 Not reported yes without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is identical to the substance Carbosulfan 259-565-9 55285-14-8 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate Carbosulfan C20H32N2O3S CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 4 Male/Female intraperitoneal 48.0000000000 h yes, concurrent vehicle not applicable Ambiguous no evidence RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is identical to the substance Carbosulfan 259-565-9 55285-14-8 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate Carbosulfan C20H32N2O3S CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3 organic compound Other Other chromosome aberration other in vitro No guideline available Not reported Not applicable Acceptable Saccharomyces cerevisiae (as organism) D7 Not reported yes with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is identical to the substance Carbosulfan 259-565-9 55285-14-8 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate Carbosulfan C20H32N2O3S CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 4 Male/Female intraperitoneal 24.0000000000 h yes, concurrent vehicle not applicable Ambiguous no evidence RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is identical to the substance Carbosulfan 259-565-9 55285-14-8 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate Carbosulfan C20H32N2O3S CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 4 Male/Female intraperitoneal 72.0000000000 h yes, concurrent vehicle not applicable Ambiguous no evidence RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is identical to the substance Carbosulfan 259-565-9 55285-14-8 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate Carbosulfan C20H32N2O3S CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3 organic compound Other Other chromosome aberration other in vitro No guideline available Not reported Not applicable Acceptable Saccharomyces cerevisiae (as organism) Not reported yes without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is identical to the substance Carbosulfan 259-565-9 55285-14-8 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate Carbosulfan C20H32N2O3S CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3 organic compound Other Other chromosome aberration other in vitro No guideline available Not reported Not applicable Acceptable Saccharomyces cerevisiae (as organism) Not reported yes with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is identical to the substance Carbosulfan 259-565-9 55285-14-8 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate Carbosulfan C20H32N2O3S CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Sprague-Dawley 10 Male oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is identical to the substance Carbosulfan 259-565-9 55285-14-8 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate Carbosulfan C20H32N2O3S CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Sprague-Dawley 10 Male oral: gavage 6.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is identical to the substance Carbosulfan 259-565-9 55285-14-8 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate Carbosulfan C20H32N2O3S CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Sprague-Dawley 10 Male oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is identical to the substance Carbosulfan 259-565-9 55285-14-8 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate Carbosulfan C20H32N2O3S CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) ICR 10 Male/Female oral: gavage 18.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is identical to the substance Carbosulfan 259-565-9 55285-14-8 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate Carbosulfan C20H32N2O3S CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) ICR 10 Male/Female oral: gavage 42.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is identical to the substance Carbosulfan 259-565-9 55285-14-8 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate Carbosulfan C20H32N2O3S CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) Swiss 3 No data oral: unspecified 24.0000000000 h yes not applicable Positive RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is identical to the substance Carbosulfan 259-565-9 55285-14-8 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate Carbosulfan C20H32N2O3S CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) Swiss 3 No data intraperitoneal 24.0000000000 h yes not applicable Positive RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is identical to the substance Carbosulfan 259-565-9 55285-14-8 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate Carbosulfan C20H32N2O3S CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) Swiss 3 No data intraperitoneal 48.0000000000 h yes not applicable Positive RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 mixture or formulation Component is the active ingredient of the mixture or formulation Carbosulfan formulation (Marshal 25CS) Not in list organic no structure chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Not reported 6 Male/Female intraperitoneal 12.0000000000 h yes not applicable Positive RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 mixture or formulation Component is the active ingredient of the mixture or formulation Carbosulfan formulation (Marshal 25CS) Not in list organic no structure chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Not reported 6 Male/Female intraperitoneal 24.0000000000 h yes not applicable Positive RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 mixture or formulation Component is the active ingredient of the mixture or formulation Carbosulfan formulation (Marshal 25CS) Not in list organic no structure chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Not reported 6 Male/Female intraperitoneal 6.0000000000 h yes not applicable Positive RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is identical to the substance Carbosulfan 259-565-9 55285-14-8 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate Carbosulfan C20H32N2O3S CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3 organic compound Other Other chromosome aberration dominant lethal assay in vivo According to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) No Acceptable House mouse (as animal) CD-1 12 Male oral: gavage yes not applicable Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) Not reported Not reported no data without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) Not reported Not reported no data with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) Not reported Not reported no data without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) Not reported Not reported no data with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Positive RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Positive RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Positive RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Positive RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Positive RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Positive RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Positive RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Positive RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Positive RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Positive RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Positive RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Positive RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Positive RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Positive RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Positive RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Positive RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Positive RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Positive RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Positive RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Positive RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Positive RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Positive RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Positive RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Human (as organism) fibroblast Not reported yes, concurrent vehicle without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Human (as organism) fibroblast Not reported yes, concurrent vehicle with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Human (as organism) fibroblast Not reported yes, concurrent vehicle with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Human (as organism) fibroblast Not reported yes, concurrent vehicle without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro Equivalent or similar to OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay) Yes Acceptable Saccharomyces cerevisiae (as organism) D3 Not reported yes without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro Equivalent or similar to OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay) Yes Acceptable Saccharomyces cerevisiae (as organism) D3 Not reported yes with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro Equivalent or similar to OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay) Yes Acceptable Saccharomyces cerevisiae (as organism) D3 Not reported yes with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro Equivalent or similar to OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay) Yes Acceptable Saccharomyces cerevisiae (as organism) D3 Not reported yes without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro No guideline available Not reported Not applicable Acceptable Salmonella typhimurium (as organism) Not reported yes without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro No guideline available Not reported Not applicable Acceptable Salmonella typhimurium (as organism) Not reported yes without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro No guideline available Not reported Not applicable Acceptable Salmonella typhimurium (as organism) Not reported yes without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro No guideline available Not reported Not applicable Acceptable Salmonella typhimurium (as organism) Not reported yes without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Positive no information RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Positive no information RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Positive no information RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Positive no information RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Positive no information RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Positive no information RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Ambiguous RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Positive RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Positive RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Ambiguous RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported no data without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported no data with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported no data without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported no data with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Human (as organism) HeLa cells Not reported yes with Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Human (as organism) HeLa cells Not reported yes without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Human (as organism) HeLa cells Not reported yes with Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Human (as organism) HeLa cells Not reported yes without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Rat (as animal) hepatocytes Not reported no data without Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Rat (as animal) hepatocytes Not reported no data without Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro According to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No Acceptable Hamster (as animal) CHO Not reported yes with Positive RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro According to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No Acceptable Hamster (as animal) CHO Not reported yes without Positive RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro According to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No Acceptable Hamster (as animal) CHO Not reported yes with Positive RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro According to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No Acceptable Hamster (as animal) CHO Not reported yes without Positive RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro According to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No Acceptable Hamster (as animal) CHO Not reported yes without Positive RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro According to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No Acceptable Hamster (as animal) CHO Not reported yes with Positive RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro According to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No Acceptable Hamster (as animal) CHO Not reported yes without Positive RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro According to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No Acceptable Hamster (as animal) CHO Not reported yes with Positive RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 72.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 72.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration mammalian germ cell cytogenetic assay in vivo Equivalent or similar to OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test) Yes Acceptable House mouse (as animal) Swiss Male intraperitoneal yes, concurrent vehicle not applicable Positive RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Swiss 4 Male oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Swiss 4 Male oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Positive indirect evidence-systemic toxicity RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) Swiss 4 No data oral: unspecified 24.0000000000 h yes not applicable Positive RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration mammalian germ cell cytogenetic assay in vivo Equivalent or similar to OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test) Yes Acceptable House mouse (as animal) Swiss Male intraperitoneal yes, concurrent vehicle not applicable Positive RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Swiss 4 Male oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Positive indirect evidence-systemic toxicity RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Swiss 4 Male oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) Swiss 4 No data oral: unspecified 24.0000000000 h yes not applicable Positive RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) SwissWebster 5 Male oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) SwissWebster 5 Male oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) SwissWebster 5 Male oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) SwissWebster 5 Male oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Sprague-Dawley 5 Male oral: gavage 6.0000000000 h no data not applicable Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Sprague-Dawley 5 Male oral: gavage 6.0000000000 h no data not applicable Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Sprague-Dawley 5 Male oral: gavage 6.0000000000 h no data not applicable Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Sprague-Dawley 5 Male oral: gavage 6.0000000000 h no data not applicable Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) SwissWebster 5 Male oral: gavage 48.0000000000 h no data not applicable Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) SwissWebster 5 Male oral: gavage 24.0000000000 h no data not applicable Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) SwissWebster 5 Male oral: gavage 48.0000000000 h no data not applicable Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) SwissWebster 5 Male oral: gavage 24.0000000000 h no data not applicable Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI genome mutation Drosophila SLRL test in vivo Equivalent or similar to OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster) Yes Acceptable Drosophila melanogaster (as animal) Not reported Male oral: feed 22.0000000000 h no data not applicable Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI genome mutation Drosophila SLRL test in vivo Equivalent or similar to OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster) Yes Acceptable Drosophila melanogaster (as animal) Not reported Male oral: feed 22.0000000000 h no data not applicable Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI genome mutation Drosophila SLRL test in vivo Equivalent or similar to OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster) Yes Acceptable Drosophila melanogaster (as animal) Not reported Male Not reported 24.0000000000 h yes not applicable Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI genome mutation Drosophila SLRL test in vivo Equivalent or similar to OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster) Yes Acceptable Drosophila melanogaster (as animal) Not reported Male Not reported 24.0000000000 h yes not applicable Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is a metabolite of the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI genome mutation Drosophila SLRL test in vivo Equivalent or similar to OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster) Yes Acceptable Drosophila melanogaster (as animal) Not reported Male oral: feed 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Belgium Carbosulfan 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbofuran 216-353-0 1563-66-2 single chemical entity Component is identical to the substance Carbofuran 216-353-0 1563-66-2 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate Carbofuran C12H15NO3 CNC(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI genome mutation Drosophila SLRL test in vivo Equivalent or similar to OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster) Yes Acceptable Drosophila melanogaster (as animal) Not reported Male oral: feed 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Belgium Carbofuran (Annex B) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran 10Jul2009 2009 doi:10.2903/j.efsa.2009.310r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is identical to the substance Chloridazon 216-920-2 1698-60-8 5-amino-4-chloro-2-phenylpyridazin-3(2H)-one Chloridazon C10H8ClN3O NC1=C(Cl)C(=O)N(N=C1)c2ccccc2 InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is identical to the substance Chloridazon 216-920-2 1698-60-8 5-amino-4-chloro-2-phenylpyridazin-3(2H)-one Chloridazon C10H8ClN3O NC1=C(Cl)C(=O)N(N=C1)c2ccccc2 InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is identical to the substance Chloridazon 216-920-2 1698-60-8 5-amino-4-chloro-2-phenylpyridazin-3(2H)-one Chloridazon C10H8ClN3O NC1=C(Cl)C(=O)N(N=C1)c2ccccc2 InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is identical to the substance Chloridazon 216-920-2 1698-60-8 5-amino-4-chloro-2-phenylpyridazin-3(2H)-one Chloridazon C10H8ClN3O NC1=C(Cl)C(=O)N(N=C1)c2ccccc2 InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is identical to the substance Chloridazon 216-920-2 1698-60-8 5-amino-4-chloro-2-phenylpyridazin-3(2H)-one Chloridazon C10H8ClN3O NC1=C(Cl)C(=O)N(N=C1)c2ccccc2 InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is identical to the substance Chloridazon 216-920-2 1698-60-8 5-amino-4-chloro-2-phenylpyridazin-3(2H)-one Chloridazon C10H8ClN3O NC1=C(Cl)C(=O)N(N=C1)c2ccccc2 InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is identical to the substance Chloridazon 216-920-2 1698-60-8 5-amino-4-chloro-2-phenylpyridazin-3(2H)-one Chloridazon C10H8ClN3O NC1=C(Cl)C(=O)N(N=C1)c2ccccc2 InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is identical to the substance Chloridazon 216-920-2 1698-60-8 5-amino-4-chloro-2-phenylpyridazin-3(2H)-one Chloridazon C10H8ClN3O NC1=C(Cl)C(=O)N(N=C1)c2ccccc2 InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is identical to the substance Chloridazon 216-920-2 1698-60-8 5-amino-4-chloro-2-phenylpyridazin-3(2H)-one Chloridazon C10H8ClN3O NC1=C(Cl)C(=O)N(N=C1)c2ccccc2 InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is identical to the substance Chloridazon 216-920-2 1698-60-8 5-amino-4-chloro-2-phenylpyridazin-3(2H)-one Chloridazon C10H8ClN3O NC1=C(Cl)C(=O)N(N=C1)c2ccccc2 InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is identical to the substance Chloridazon 216-920-2 1698-60-8 5-amino-4-chloro-2-phenylpyridazin-3(2H)-one Chloridazon C10H8ClN3O NC1=C(Cl)C(=O)N(N=C1)c2ccccc2 InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is identical to the substance Chloridazon 216-920-2 1698-60-8 5-amino-4-chloro-2-phenylpyridazin-3(2H)-one Chloridazon C10H8ClN3O NC1=C(Cl)C(=O)N(N=C1)c2ccccc2 InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is identical to the substance Chloridazon 216-920-2 1698-60-8 5-amino-4-chloro-2-phenylpyridazin-3(2H)-one Chloridazon C10H8ClN3O NC1=C(Cl)C(=O)N(N=C1)c2ccccc2 InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is identical to the substance Chloridazon 216-920-2 1698-60-8 5-amino-4-chloro-2-phenylpyridazin-3(2H)-one Chloridazon C10H8ClN3O NC1=C(Cl)C(=O)N(N=C1)c2ccccc2 InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is identical to the substance Chloridazon 216-920-2 1698-60-8 5-amino-4-chloro-2-phenylpyridazin-3(2H)-one Chloridazon C10H8ClN3O NC1=C(Cl)C(=O)N(N=C1)c2ccccc2 InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is identical to the substance Chloridazon 216-920-2 1698-60-8 5-amino-4-chloro-2-phenylpyridazin-3(2H)-one Chloridazon C10H8ClN3O NC1=C(Cl)C(=O)N(N=C1)c2ccccc2 InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is identical to the substance Chloridazon 216-920-2 1698-60-8 5-amino-4-chloro-2-phenylpyridazin-3(2H)-one Chloridazon C10H8ClN3O NC1=C(Cl)C(=O)N(N=C1)c2ccccc2 InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is identical to the substance Chloridazon 216-920-2 1698-60-8 5-amino-4-chloro-2-phenylpyridazin-3(2H)-one Chloridazon C10H8ClN3O NC1=C(Cl)C(=O)N(N=C1)c2ccccc2 InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is identical to the substance Chloridazon 216-920-2 1698-60-8 5-amino-4-chloro-2-phenylpyridazin-3(2H)-one Chloridazon C10H8ClN3O NC1=C(Cl)C(=O)N(N=C1)c2ccccc2 InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is identical to the substance Chloridazon 216-920-2 1698-60-8 5-amino-4-chloro-2-phenylpyridazin-3(2H)-one Chloridazon C10H8ClN3O NC1=C(Cl)C(=O)N(N=C1)c2ccccc2 InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is identical to the substance Chloridazon 216-920-2 1698-60-8 5-amino-4-chloro-2-phenylpyridazin-3(2H)-one Chloridazon C10H8ClN3O NC1=C(Cl)C(=O)N(N=C1)c2ccccc2 InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is identical to the substance Chloridazon 216-920-2 1698-60-8 5-amino-4-chloro-2-phenylpyridazin-3(2H)-one Chloridazon C10H8ClN3O NC1=C(Cl)C(=O)N(N=C1)c2ccccc2 InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is identical to the substance Chloridazon 216-920-2 1698-60-8 5-amino-4-chloro-2-phenylpyridazin-3(2H)-one Chloridazon C10H8ClN3O NC1=C(Cl)C(=O)N(N=C1)c2ccccc2 InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is identical to the substance Chloridazon 216-920-2 1698-60-8 5-amino-4-chloro-2-phenylpyridazin-3(2H)-one Chloridazon C10H8ClN3O NC1=C(Cl)C(=O)N(N=C1)c2ccccc2 InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is identical to the substance Chloridazon 216-920-2 1698-60-8 5-amino-4-chloro-2-phenylpyridazin-3(2H)-one Chloridazon C10H8ClN3O NC1=C(Cl)C(=O)N(N=C1)c2ccccc2 InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is identical to the substance Chloridazon 216-920-2 1698-60-8 5-amino-4-chloro-2-phenylpyridazin-3(2H)-one Chloridazon C10H8ClN3O NC1=C(Cl)C(=O)N(N=C1)c2ccccc2 InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is identical to the substance Chloridazon 216-920-2 1698-60-8 5-amino-4-chloro-2-phenylpyridazin-3(2H)-one Chloridazon C10H8ClN3O NC1=C(Cl)C(=O)N(N=C1)c2ccccc2 InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle without Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is identical to the substance Chloridazon 216-920-2 1698-60-8 5-amino-4-chloro-2-phenylpyridazin-3(2H)-one Chloridazon C10H8ClN3O NC1=C(Cl)C(=O)N(N=C1)c2ccccc2 InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2 organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes, concurrent vehicle without Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is identical to the substance Chloridazon 216-920-2 1698-60-8 5-amino-4-chloro-2-phenylpyridazin-3(2H)-one Chloridazon C10H8ClN3O NC1=C(Cl)C(=O)N(N=C1)c2ccccc2 InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is identical to the substance Chloridazon 216-920-2 1698-60-8 5-amino-4-chloro-2-phenylpyridazin-3(2H)-one Chloridazon C10H8ClN3O NC1=C(Cl)C(=O)N(N=C1)c2ccccc2 InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is identical to the substance Chloridazon 216-920-2 1698-60-8 5-amino-4-chloro-2-phenylpyridazin-3(2H)-one Chloridazon C10H8ClN3O NC1=C(Cl)C(=O)N(N=C1)c2ccccc2 InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is identical to the substance Chloridazon 216-920-2 1698-60-8 5-amino-4-chloro-2-phenylpyridazin-3(2H)-one Chloridazon C10H8ClN3O NC1=C(Cl)C(=O)N(N=C1)c2ccccc2 InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is identical to the substance Chloridazon 216-920-2 1698-60-8 5-amino-4-chloro-2-phenylpyridazin-3(2H)-one Chloridazon C10H8ClN3O NC1=C(Cl)C(=O)N(N=C1)c2ccccc2 InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is identical to the substance Chloridazon 216-920-2 1698-60-8 5-amino-4-chloro-2-phenylpyridazin-3(2H)-one Chloridazon C10H8ClN3O NC1=C(Cl)C(=O)N(N=C1)c2ccccc2 InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle with Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is identical to the substance Chloridazon 216-920-2 1698-60-8 5-amino-4-chloro-2-phenylpyridazin-3(2H)-one Chloridazon C10H8ClN3O NC1=C(Cl)C(=O)N(N=C1)c2ccccc2 InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2 organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes, concurrent vehicle without Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is identical to the substance Chloridazon 216-920-2 1698-60-8 5-amino-4-chloro-2-phenylpyridazin-3(2H)-one Chloridazon C10H8ClN3O NC1=C(Cl)C(=O)N(N=C1)c2ccccc2 InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is identical to the substance Chloridazon 216-920-2 1698-60-8 5-amino-4-chloro-2-phenylpyridazin-3(2H)-one Chloridazon C10H8ClN3O NC1=C(Cl)C(=O)N(N=C1)c2ccccc2 InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is identical to the substance Chloridazon 216-920-2 1698-60-8 5-amino-4-chloro-2-phenylpyridazin-3(2H)-one Chloridazon C10H8ClN3O NC1=C(Cl)C(=O)N(N=C1)c2ccccc2 InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is identical to the substance Chloridazon 216-920-2 1698-60-8 5-amino-4-chloro-2-phenylpyridazin-3(2H)-one Chloridazon C10H8ClN3O NC1=C(Cl)C(=O)N(N=C1)c2ccccc2 InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is identical to the substance Chloridazon 216-920-2 1698-60-8 5-amino-4-chloro-2-phenylpyridazin-3(2H)-one Chloridazon C10H8ClN3O NC1=C(Cl)C(=O)N(N=C1)c2ccccc2 InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is identical to the substance Chloridazon 216-920-2 1698-60-8 5-amino-4-chloro-2-phenylpyridazin-3(2H)-one Chloridazon C10H8ClN3O NC1=C(Cl)C(=O)N(N=C1)c2ccccc2 InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Positive RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is identical to the substance Chloridazon 216-920-2 1698-60-8 5-amino-4-chloro-2-phenylpyridazin-3(2H)-one Chloridazon C10H8ClN3O NC1=C(Cl)C(=O)N(N=C1)c2ccccc2 InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is identical to the substance Chloridazon 216-920-2 1698-60-8 5-amino-4-chloro-2-phenylpyridazin-3(2H)-one Chloridazon C10H8ClN3O NC1=C(Cl)C(=O)N(N=C1)c2ccccc2 InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Positive RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is identical to the substance Chloridazon 216-920-2 1698-60-8 5-amino-4-chloro-2-phenylpyridazin-3(2H)-one Chloridazon C10H8ClN3O NC1=C(Cl)C(=O)N(N=C1)c2ccccc2 InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Positive RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is identical to the substance Chloridazon 216-920-2 1698-60-8 5-amino-4-chloro-2-phenylpyridazin-3(2H)-one Chloridazon C10H8ClN3O NC1=C(Cl)C(=O)N(N=C1)c2ccccc2 InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Positive RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is identical to the substance Chloridazon 216-920-2 1698-60-8 5-amino-4-chloro-2-phenylpyridazin-3(2H)-one Chloridazon C10H8ClN3O NC1=C(Cl)C(=O)N(N=C1)c2ccccc2 InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is identical to the substance Chloridazon 216-920-2 1698-60-8 5-amino-4-chloro-2-phenylpyridazin-3(2H)-one Chloridazon C10H8ClN3O NC1=C(Cl)C(=O)N(N=C1)c2ccccc2 InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is identical to the substance Chloridazon 216-920-2 1698-60-8 5-amino-4-chloro-2-phenylpyridazin-3(2H)-one Chloridazon C10H8ClN3O NC1=C(Cl)C(=O)N(N=C1)c2ccccc2 InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is identical to the substance Chloridazon 216-920-2 1698-60-8 5-amino-4-chloro-2-phenylpyridazin-3(2H)-one Chloridazon C10H8ClN3O NC1=C(Cl)C(=O)N(N=C1)c2ccccc2 InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is identical to the substance Chloridazon 216-920-2 1698-60-8 5-amino-4-chloro-2-phenylpyridazin-3(2H)-one Chloridazon C10H8ClN3O NC1=C(Cl)C(=O)N(N=C1)c2ccccc2 InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is identical to the substance Chloridazon 216-920-2 1698-60-8 5-amino-4-chloro-2-phenylpyridazin-3(2H)-one Chloridazon C10H8ClN3O NC1=C(Cl)C(=O)N(N=C1)c2ccccc2 InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2 organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes without Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is identical to the substance Chloridazon 216-920-2 1698-60-8 5-amino-4-chloro-2-phenylpyridazin-3(2H)-one Chloridazon C10H8ClN3O NC1=C(Cl)C(=O)N(N=C1)c2ccccc2 InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2 organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes with Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is identical to the substance Chloridazon 216-920-2 1698-60-8 5-amino-4-chloro-2-phenylpyridazin-3(2H)-one Chloridazon C10H8ClN3O NC1=C(Cl)C(=O)N(N=C1)c2ccccc2 InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2 organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes with Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is identical to the substance Chloridazon 216-920-2 1698-60-8 5-amino-4-chloro-2-phenylpyridazin-3(2H)-one Chloridazon C10H8ClN3O NC1=C(Cl)C(=O)N(N=C1)c2ccccc2 InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2 organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes without Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is identical to the substance Chloridazon 216-920-2 1698-60-8 5-amino-4-chloro-2-phenylpyridazin-3(2H)-one Chloridazon C10H8ClN3O NC1=C(Cl)C(=O)N(N=C1)c2ccccc2 InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2 organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is identical to the substance Chloridazon 216-920-2 1698-60-8 5-amino-4-chloro-2-phenylpyridazin-3(2H)-one Chloridazon C10H8ClN3O NC1=C(Cl)C(=O)N(N=C1)c2ccccc2 InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 16.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is identical to the substance Chloridazon 216-920-2 1698-60-8 5-amino-4-chloro-2-phenylpyridazin-3(2H)-one Chloridazon C10H8ClN3O NC1=C(Cl)C(=O)N(N=C1)c2ccccc2 InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is identical to the substance Chloridazon 216-920-2 1698-60-8 5-amino-4-chloro-2-phenylpyridazin-3(2H)-one Chloridazon C10H8ClN3O NC1=C(Cl)C(=O)N(N=C1)c2ccccc2 InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is identical to the substance Chloridazon 216-920-2 1698-60-8 5-amino-4-chloro-2-phenylpyridazin-3(2H)-one Chloridazon C10H8ClN3O NC1=C(Cl)C(=O)N(N=C1)c2ccccc2 InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2 organic compound Other Other chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) Yes Acceptable House mouse (as animal) NMRI Male oral: gavage yes, concurrent vehicle not applicable Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is identical to the substance Chloridazon 216-920-2 1698-60-8 5-amino-4-chloro-2-phenylpyridazin-3(2H)-one Chloridazon C10H8ClN3O NC1=C(Cl)C(=O)N(N=C1)c2ccccc2 InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2 organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro No guideline followed Not reported Not applicable Acceptable Bovinae (bovines = Tribe bovini) (as animal) lymphocytes Not reported yes, concurrent vehicle without Positive RMS: Germany Chloridazon (Final Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is identical to the substance Chloridazon 216-920-2 1698-60-8 5-amino-4-chloro-2-phenylpyridazin-3(2H)-one Chloridazon C10H8ClN3O NC1=C(Cl)C(=O)N(N=C1)c2ccccc2 InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2 organic compound Other Other chromosome aberration in vitro mammalian cell micronucleus test in vitro No guideline followed Not reported Not applicable Acceptable Bovinae (bovines = Tribe bovini) (as animal) lymphocytes Not reported yes, concurrent vehicle without Positive RMS: Germany Chloridazon (Final Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is identical to the substance Chloridazon 216-920-2 1698-60-8 5-amino-4-chloro-2-phenylpyridazin-3(2H)-one Chloridazon C10H8ClN3O NC1=C(Cl)C(=O)N(N=C1)c2ccccc2 InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2 organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro No guideline followed Not reported Not applicable Acceptable Bovinae (bovines = Tribe bovini) (as animal) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Germany Chloridazon (Final Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is identical to the substance Chloridazon 216-920-2 1698-60-8 5-amino-4-chloro-2-phenylpyridazin-3(2H)-one Chloridazon C10H8ClN3O NC1=C(Cl)C(=O)N(N=C1)c2ccccc2 InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro No guideline followed Not reported Not applicable Acceptable Bovinae (bovines = Tribe bovini) (as animal) lymphocytes Not reported yes, concurrent vehicle without Positive RMS: Germany Chloridazon (Final Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is a metabolite of the substance 5-amino-4-chloro-3(2H)-pyridazinone 6339-19-1 4-amino-5-chloro-1H-pyridazin-6-one Not in list C4H4ClN3O C1=NNC(=O)C(=C1N)Cl InChI=1S/C4H4ClN3O/c5-3-2(6)1-7-8-4(3)9/h1H,(H3,6,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is a metabolite of the substance 5-amino-4-chloro-3(2H)-pyridazinone 6339-19-1 4-amino-5-chloro-1H-pyridazin-6-one Not in list C4H4ClN3O C1=NNC(=O)C(=C1N)Cl InChI=1S/C4H4ClN3O/c5-3-2(6)1-7-8-4(3)9/h1H,(H3,6,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is a metabolite of the substance 5-amino-4-chloro-3(2H)-pyridazinone 6339-19-1 4-amino-5-chloro-1H-pyridazin-6-one Not in list C4H4ClN3O C1=NNC(=O)C(=C1N)Cl InChI=1S/C4H4ClN3O/c5-3-2(6)1-7-8-4(3)9/h1H,(H3,6,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is a metabolite of the substance 5-amino-4-chloro-3(2H)-pyridazinone 6339-19-1 4-amino-5-chloro-1H-pyridazin-6-one Not in list C4H4ClN3O C1=NNC(=O)C(=C1N)Cl InChI=1S/C4H4ClN3O/c5-3-2(6)1-7-8-4(3)9/h1H,(H3,6,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is a metabolite of the substance 5-amino-4-chloro-3(2H)-pyridazinone 6339-19-1 4-amino-5-chloro-1H-pyridazin-6-one Not in list C4H4ClN3O C1=NNC(=O)C(=C1N)Cl InChI=1S/C4H4ClN3O/c5-3-2(6)1-7-8-4(3)9/h1H,(H3,6,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is a metabolite of the substance 5-amino-4-chloro-3(2H)-pyridazinone 6339-19-1 4-amino-5-chloro-1H-pyridazin-6-one Not in list C4H4ClN3O C1=NNC(=O)C(=C1N)Cl InChI=1S/C4H4ClN3O/c5-3-2(6)1-7-8-4(3)9/h1H,(H3,6,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is a metabolite of the substance 5-amino-4-chloro-3(2H)-pyridazinone 6339-19-1 4-amino-5-chloro-1H-pyridazin-6-one Not in list C4H4ClN3O C1=NNC(=O)C(=C1N)Cl InChI=1S/C4H4ClN3O/c5-3-2(6)1-7-8-4(3)9/h1H,(H3,6,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is a metabolite of the substance 5-amino-4-chloro-3(2H)-pyridazinone 6339-19-1 4-amino-5-chloro-1H-pyridazin-6-one Not in list C4H4ClN3O C1=NNC(=O)C(=C1N)Cl InChI=1S/C4H4ClN3O/c5-3-2(6)1-7-8-4(3)9/h1H,(H3,6,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is a metabolite of the substance 5-amino-4-chloro-3(2H)-pyridazinone 6339-19-1 4-amino-5-chloro-1H-pyridazin-6-one Not in list C4H4ClN3O C1=NNC(=O)C(=C1N)Cl InChI=1S/C4H4ClN3O/c5-3-2(6)1-7-8-4(3)9/h1H,(H3,6,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is a metabolite of the substance 5-amino-4-chloro-3(2H)-pyridazinone 6339-19-1 4-amino-5-chloro-1H-pyridazin-6-one Not in list C4H4ClN3O C1=NNC(=O)C(=C1N)Cl InChI=1S/C4H4ClN3O/c5-3-2(6)1-7-8-4(3)9/h1H,(H3,6,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is a metabolite of the substance 5-amino-4-chloro-3(2H)-pyridazinone 6339-19-1 4-amino-5-chloro-1H-pyridazin-6-one Not in list C4H4ClN3O C1=NNC(=O)C(=C1N)Cl InChI=1S/C4H4ClN3O/c5-3-2(6)1-7-8-4(3)9/h1H,(H3,6,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is a metabolite of the substance 5-amino-4-chloro-3(2H)-pyridazinone 6339-19-1 4-amino-5-chloro-1H-pyridazin-6-one Not in list C4H4ClN3O C1=NNC(=O)C(=C1N)Cl InChI=1S/C4H4ClN3O/c5-3-2(6)1-7-8-4(3)9/h1H,(H3,6,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is a metabolite of the substance 5-amino-4-chloro-2-methyl-3(2H)-pyridazinone 605-639-4 17254-80-7 5-amino-4-chloro-2-methylpyridazin-3-one Not in list C5H6ClN3O CN1C(=O)C(=C(C=N1)N)Cl InChI=1S/C5H6ClN3O/c1-9-5(10)4(6)3(7)2-8-9/h2H,7H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is a metabolite of the substance 5-amino-4-chloro-2-methyl-3(2H)-pyridazinone 605-639-4 17254-80-7 5-amino-4-chloro-2-methylpyridazin-3-one Not in list C5H6ClN3O CN1C(=O)C(=C(C=N1)N)Cl InChI=1S/C5H6ClN3O/c1-9-5(10)4(6)3(7)2-8-9/h2H,7H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is a metabolite of the substance 5-amino-4-chloro-2-methyl-3(2H)-pyridazinone 605-639-4 17254-80-7 5-amino-4-chloro-2-methylpyridazin-3-one Not in list C5H6ClN3O CN1C(=O)C(=C(C=N1)N)Cl InChI=1S/C5H6ClN3O/c1-9-5(10)4(6)3(7)2-8-9/h2H,7H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is a metabolite of the substance 5-amino-4-chloro-2-methyl-3(2H)-pyridazinone 605-639-4 17254-80-7 5-amino-4-chloro-2-methylpyridazin-3-one Not in list C5H6ClN3O CN1C(=O)C(=C(C=N1)N)Cl InChI=1S/C5H6ClN3O/c1-9-5(10)4(6)3(7)2-8-9/h2H,7H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is a metabolite of the substance 5-amino-4-chloro-2-methyl-3(2H)-pyridazinone 605-639-4 17254-80-7 5-amino-4-chloro-2-methylpyridazin-3-one Not in list C5H6ClN3O CN1C(=O)C(=C(C=N1)N)Cl InChI=1S/C5H6ClN3O/c1-9-5(10)4(6)3(7)2-8-9/h2H,7H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is a metabolite of the substance 5-amino-4-chloro-2-methyl-3(2H)-pyridazinone 605-639-4 17254-80-7 5-amino-4-chloro-2-methylpyridazin-3-one Not in list C5H6ClN3O CN1C(=O)C(=C(C=N1)N)Cl InChI=1S/C5H6ClN3O/c1-9-5(10)4(6)3(7)2-8-9/h2H,7H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is a metabolite of the substance 5-amino-4-chloro-2-methyl-3(2H)-pyridazinone 605-639-4 17254-80-7 5-amino-4-chloro-2-methylpyridazin-3-one Not in list C5H6ClN3O CN1C(=O)C(=C(C=N1)N)Cl InChI=1S/C5H6ClN3O/c1-9-5(10)4(6)3(7)2-8-9/h2H,7H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is a metabolite of the substance 5-amino-4-chloro-2-methyl-3(2H)-pyridazinone 605-639-4 17254-80-7 5-amino-4-chloro-2-methylpyridazin-3-one Not in list C5H6ClN3O CN1C(=O)C(=C(C=N1)N)Cl InChI=1S/C5H6ClN3O/c1-9-5(10)4(6)3(7)2-8-9/h2H,7H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is a metabolite of the substance 5-amino-4-chloro-2-methyl-3(2H)-pyridazinone 605-639-4 17254-80-7 5-amino-4-chloro-2-methylpyridazin-3-one Not in list C5H6ClN3O CN1C(=O)C(=C(C=N1)N)Cl InChI=1S/C5H6ClN3O/c1-9-5(10)4(6)3(7)2-8-9/h2H,7H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is a metabolite of the substance 5-amino-4-chloro-2-methyl-3(2H)-pyridazinone 605-639-4 17254-80-7 5-amino-4-chloro-2-methylpyridazin-3-one Not in list C5H6ClN3O CN1C(=O)C(=C(C=N1)N)Cl InChI=1S/C5H6ClN3O/c1-9-5(10)4(6)3(7)2-8-9/h2H,7H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is a metabolite of the substance 5-amino-4-chloro-2-methyl-3(2H)-pyridazinone 605-639-4 17254-80-7 5-amino-4-chloro-2-methylpyridazin-3-one Not in list C5H6ClN3O CN1C(=O)C(=C(C=N1)N)Cl InChI=1S/C5H6ClN3O/c1-9-5(10)4(6)3(7)2-8-9/h2H,7H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is a metabolite of the substance 5-amino-4-chloro-2-methyl-3(2H)-pyridazinone 605-639-4 17254-80-7 5-amino-4-chloro-2-methylpyridazin-3-one Not in list C5H6ClN3O CN1C(=O)C(=C(C=N1)N)Cl InChI=1S/C5H6ClN3O/c1-9-5(10)4(6)3(7)2-8-9/h2H,7H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is a metabolite of the substance 5-amino-4-chloro-2-methyl-3(2H)-pyridazinone 605-639-4 17254-80-7 5-amino-4-chloro-2-methylpyridazin-3-one Not in list C5H6ClN3O CN1C(=O)C(=C(C=N1)N)Cl InChI=1S/C5H6ClN3O/c1-9-5(10)4(6)3(7)2-8-9/h2H,7H2,1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes without Negative RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is a metabolite of the substance 5-amino-4-chloro-2-methyl-3(2H)-pyridazinone 605-639-4 17254-80-7 5-amino-4-chloro-2-methylpyridazin-3-one Not in list C5H6ClN3O CN1C(=O)C(=C(C=N1)N)Cl InChI=1S/C5H6ClN3O/c1-9-5(10)4(6)3(7)2-8-9/h2H,7H2,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable Rat (as animal) Wistar Male oral: unspecified 20.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chloridazon 216-920-2 1698-60-8 single chemical entity Component is a metabolite of the substance 5-amino-4-chloro-2-methyl-3(2H)-pyridazinone 605-639-4 17254-80-7 5-amino-4-chloro-2-methylpyridazin-3-one Not in list C5H6ClN3O CN1C(=O)C(=C(C=N1)N)Cl InChI=1S/C5H6ClN3O/c1-9-5(10)4(6)3(7)2-8-9/h2H,7H2,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable Rat (as animal) Wistar Male oral: unspecified 44.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Germany Chloridazon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon 13Aug2007 2007 doi:10.2903/j.efsa.2007.108r
+Chromafenozide 143807-66-3 single chemical entity Component is identical to the substance Chromafenozide 143807-66-3 N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide Chromafenozide C24H30N2O3 CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is identical to the substance Chromafenozide 143807-66-3 N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide Chromafenozide C24H30N2O3 CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is identical to the substance Chromafenozide 143807-66-3 N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide Chromafenozide C24H30N2O3 CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is identical to the substance Chromafenozide 143807-66-3 N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide Chromafenozide C24H30N2O3 CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is identical to the substance Chromafenozide 143807-66-3 N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide Chromafenozide C24H30N2O3 CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is identical to the substance Chromafenozide 143807-66-3 N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide Chromafenozide C24H30N2O3 CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is identical to the substance Chromafenozide 143807-66-3 N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide Chromafenozide C24H30N2O3 CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is identical to the substance Chromafenozide 143807-66-3 N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide Chromafenozide C24H30N2O3 CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is identical to the substance Chromafenozide 143807-66-3 N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide Chromafenozide C24H30N2O3 CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is identical to the substance Chromafenozide 143807-66-3 N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide Chromafenozide C24H30N2O3 CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is identical to the substance Chromafenozide 143807-66-3 N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide Chromafenozide C24H30N2O3 CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is identical to the substance Chromafenozide 143807-66-3 N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide Chromafenozide C24H30N2O3 CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is identical to the substance Chromafenozide 143807-66-3 N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide Chromafenozide C24H30N2O3 CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is identical to the substance Chromafenozide 143807-66-3 N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide Chromafenozide C24H30N2O3 CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is identical to the substance Chromafenozide 143807-66-3 N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide Chromafenozide C24H30N2O3 CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is identical to the substance Chromafenozide 143807-66-3 N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide Chromafenozide C24H30N2O3 CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is identical to the substance Chromafenozide 143807-66-3 N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide Chromafenozide C24H30N2O3 CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is identical to the substance Chromafenozide 143807-66-3 N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide Chromafenozide C24H30N2O3 CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is identical to the substance Chromafenozide 143807-66-3 N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide Chromafenozide C24H30N2O3 CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is identical to the substance Chromafenozide 143807-66-3 N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide Chromafenozide C24H30N2O3 CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is identical to the substance Chromafenozide 143807-66-3 N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide Chromafenozide C24H30N2O3 CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is identical to the substance Chromafenozide 143807-66-3 N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide Chromafenozide C24H30N2O3 CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is identical to the substance Chromafenozide 143807-66-3 N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide Chromafenozide C24H30N2O3 CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative no information RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is identical to the substance Chromafenozide 143807-66-3 N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide Chromafenozide C24H30N2O3 CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Negative no information RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is identical to the substance Chromafenozide 143807-66-3 N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide Chromafenozide C24H30N2O3 CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes, concurrent vehicle without Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is identical to the substance Chromafenozide 143807-66-3 N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide Chromafenozide C24H30N2O3 CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes, concurrent vehicle without Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is identical to the substance Chromafenozide 143807-66-3 N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide Chromafenozide C24H30N2O3 CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes, concurrent vehicle with Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is identical to the substance Chromafenozide 143807-66-3 N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide Chromafenozide C24H30N2O3 CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes, concurrent vehicle with Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is identical to the substance Chromafenozide 143807-66-3 N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide Chromafenozide C24H30N2O3 CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable Rat (as animal) Sprague-Dawley 10 Male/Female intraperitoneal 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is a metabolite of the substance N‟-tert-butyl-N‟-(5-methyl-6-chromancarbonyl)-5-methyl-6-chroman-carbohydrazide Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is a metabolite of the substance N‟-tert-butyl-N‟-(5-methyl-6-chromancarbonyl)-5-methyl-6-chroman-carbohydrazide Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is a metabolite of the substance N‟-tert-butyl-N‟-(5-methyl-6-chromancarbonyl)-5-methyl-6-chroman-carbohydrazide Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is a metabolite of the substance N‟-tert-butyl-N‟-(5-methyl-6-chromancarbonyl)-5-methyl-6-chroman-carbohydrazide Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is a metabolite of the substance N‟-tert-butyl-N‟-(5-methyl-6-chromancarbonyl)-5-methyl-6-chroman-carbohydrazide Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is a metabolite of the substance N‟-tert-butyl-N‟-(5-methyl-6-chromancarbonyl)-5-methyl-6-chroman-carbohydrazide Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is a metabolite of the substance N‟-tert-butyl-N‟-(5-methyl-6-chromancarbonyl)-5-methyl-6-chroman-carbohydrazide Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is a metabolite of the substance N‟-tert-butyl-N‟-(5-methyl-6-chromancarbonyl)-5-methyl-6-chroman-carbohydrazide Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is a metabolite of the substance N‟-tert-butyl-N‟-(5-methyl-6-chromancarbonyl)-5-methyl-6-chroman-carbohydrazide Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is a metabolite of the substance N‟-tert-butyl-N‟-(5-methyl-6-chromancarbonyl)-5-methyl-6-chroman-carbohydrazide Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is a metabolite of the substance N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide Not in list C24H30N2O4 Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is a metabolite of the substance N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide Not in list C24H30N2O4 Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is a metabolite of the substance N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide Not in list C24H30N2O4 Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is a metabolite of the substance N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide Not in list C24H30N2O4 Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is a metabolite of the substance N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide Not in list C24H30N2O4 Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is a metabolite of the substance N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide Not in list C24H30N2O4 Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is a metabolite of the substance N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide Not in list C24H30N2O4 Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is a metabolite of the substance N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide Not in list C24H30N2O4 Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is a metabolite of the substance N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide Not in list C24H30N2O4 Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is a metabolite of the substance N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide Not in list C24H30N2O4 Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is a metabolite of the substance N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide Not in list C24H30N2O4 Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is a metabolite of the substance N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide Not in list C24H30N2O4 Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is a metabolite of the substance N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide Not in list C24H30N2O4 Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is a metabolite of the substance N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide Not in list C24H30N2O4 Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is a metabolite of the substance N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide Not in list C24H28N2O4 Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OC(=O)CCc2c3C)C(C)(C)C InChI=1/C24H28N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)19-7-9-20-18(16(19)3)8-10-21(27)30-20/h7,9,11-13H,8,10H2,1-6H3,(H,25,28) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is a metabolite of the substance N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide Not in list C24H28N2O4 Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OC(=O)CCc2c3C)C(C)(C)C InChI=1/C24H28N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)19-7-9-20-18(16(19)3)8-10-21(27)30-20/h7,9,11-13H,8,10H2,1-6H3,(H,25,28) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is a metabolite of the substance N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide Not in list C24H28N2O4 Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OC(=O)CCc2c3C)C(C)(C)C InChI=1/C24H28N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)19-7-9-20-18(16(19)3)8-10-21(27)30-20/h7,9,11-13H,8,10H2,1-6H3,(H,25,28) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is a metabolite of the substance N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide Not in list C24H28N2O4 Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OC(=O)CCc2c3C)C(C)(C)C InChI=1/C24H28N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)19-7-9-20-18(16(19)3)8-10-21(27)30-20/h7,9,11-13H,8,10H2,1-6H3,(H,25,28) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is a metabolite of the substance N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide Not in list C24H28N2O4 Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OC(=O)CCc2c3C)C(C)(C)C InChI=1/C24H28N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)19-7-9-20-18(16(19)3)8-10-21(27)30-20/h7,9,11-13H,8,10H2,1-6H3,(H,25,28) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is a metabolite of the substance N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide Not in list C24H28N2O4 Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OC(=O)CCc2c3C)C(C)(C)C InChI=1/C24H28N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)19-7-9-20-18(16(19)3)8-10-21(27)30-20/h7,9,11-13H,8,10H2,1-6H3,(H,25,28) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is a metabolite of the substance N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide Not in list C24H28N2O4 Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OC(=O)CCc2c3C)C(C)(C)C InChI=1/C24H28N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)19-7-9-20-18(16(19)3)8-10-21(27)30-20/h7,9,11-13H,8,10H2,1-6H3,(H,25,28) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is a metabolite of the substance N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide Not in list C24H28N2O4 Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OC(=O)CCc2c3C)C(C)(C)C InChI=1/C24H28N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)19-7-9-20-18(16(19)3)8-10-21(27)30-20/h7,9,11-13H,8,10H2,1-6H3,(H,25,28) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is a metabolite of the substance N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide Not in list C24H28N2O4 Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OC(=O)CCc2c3C)C(C)(C)C InChI=1/C24H28N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)19-7-9-20-18(16(19)3)8-10-21(27)30-20/h7,9,11-13H,8,10H2,1-6H3,(H,25,28) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is a metabolite of the substance N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide Not in list C24H28N2O4 Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OC(=O)CCc2c3C)C(C)(C)C InChI=1/C24H28N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)19-7-9-20-18(16(19)3)8-10-21(27)30-20/h7,9,11-13H,8,10H2,1-6H3,(H,25,28) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is a metabolite of the substance 3-({1-tert-butyl-2-[(4-hydroxy-5-methyl-3,4-dihydro-2H-chromen-6-yl)carbonyl]hydrazinyl}carbonyl)-5-methylbenzoic acid 3-({1-tert-butyl-2-[(4-hydroxy-5-methyl-3,4-dihydro-2H-chromen-6-yl)carbonyl]hydrazinyl}carbonyl)-5-methylbenzoic acid Not in list C24H28N2O6 O=C(O)c1cc(C)cc(c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C InChI=1/C24H28N2O6/c1-13-10-15(12-16(11-13)23(30)31)22(29)26(24(3,4)5)25-21(28)17-6-7-19-20(14(17)2)18(27)8-9-32-19/h6-7,10-12,18,27H,8-9H2,1-5H3,(H,25,28)(H,30,31) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is a metabolite of the substance 3-({1-tert-butyl-2-[(4-hydroxy-5-methyl-3,4-dihydro-2H-chromen-6-yl)carbonyl]hydrazinyl}carbonyl)-5-methylbenzoic acid 3-({1-tert-butyl-2-[(4-hydroxy-5-methyl-3,4-dihydro-2H-chromen-6-yl)carbonyl]hydrazinyl}carbonyl)-5-methylbenzoic acid Not in list C24H28N2O6 O=C(O)c1cc(C)cc(c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C InChI=1/C24H28N2O6/c1-13-10-15(12-16(11-13)23(30)31)22(29)26(24(3,4)5)25-21(28)17-6-7-19-20(14(17)2)18(27)8-9-32-19/h6-7,10-12,18,27H,8-9H2,1-5H3,(H,25,28)(H,30,31) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is a metabolite of the substance 3-({1-tert-butyl-2-[(4-hydroxy-5-methyl-3,4-dihydro-2H-chromen-6-yl)carbonyl]hydrazinyl}carbonyl)-5-methylbenzoic acid 3-({1-tert-butyl-2-[(4-hydroxy-5-methyl-3,4-dihydro-2H-chromen-6-yl)carbonyl]hydrazinyl}carbonyl)-5-methylbenzoic acid Not in list C24H28N2O6 O=C(O)c1cc(C)cc(c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C InChI=1/C24H28N2O6/c1-13-10-15(12-16(11-13)23(30)31)22(29)26(24(3,4)5)25-21(28)17-6-7-19-20(14(17)2)18(27)8-9-32-19/h6-7,10-12,18,27H,8-9H2,1-5H3,(H,25,28)(H,30,31) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is a metabolite of the substance 3-({1-tert-butyl-2-[(4-hydroxy-5-methyl-3,4-dihydro-2H-chromen-6-yl)carbonyl]hydrazinyl}carbonyl)-5-methylbenzoic acid 3-({1-tert-butyl-2-[(4-hydroxy-5-methyl-3,4-dihydro-2H-chromen-6-yl)carbonyl]hydrazinyl}carbonyl)-5-methylbenzoic acid Not in list C24H28N2O6 O=C(O)c1cc(C)cc(c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C InChI=1/C24H28N2O6/c1-13-10-15(12-16(11-13)23(30)31)22(29)26(24(3,4)5)25-21(28)17-6-7-19-20(14(17)2)18(27)8-9-32-19/h6-7,10-12,18,27H,8-9H2,1-5H3,(H,25,28)(H,30,31) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is a metabolite of the substance 3-({1-tert-butyl-2-[(4-hydroxy-5-methyl-3,4-dihydro-2H-chromen-6-yl)carbonyl]hydrazinyl}carbonyl)-5-methylbenzoic acid 3-({1-tert-butyl-2-[(4-hydroxy-5-methyl-3,4-dihydro-2H-chromen-6-yl)carbonyl]hydrazinyl}carbonyl)-5-methylbenzoic acid Not in list C24H28N2O6 O=C(O)c1cc(C)cc(c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C InChI=1/C24H28N2O6/c1-13-10-15(12-16(11-13)23(30)31)22(29)26(24(3,4)5)25-21(28)17-6-7-19-20(14(17)2)18(27)8-9-32-19/h6-7,10-12,18,27H,8-9H2,1-5H3,(H,25,28)(H,30,31) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is a metabolite of the substance 3-({1-tert-butyl-2-[(4-hydroxy-5-methyl-3,4-dihydro-2H-chromen-6-yl)carbonyl]hydrazinyl}carbonyl)-5-methylbenzoic acid 3-({1-tert-butyl-2-[(4-hydroxy-5-methyl-3,4-dihydro-2H-chromen-6-yl)carbonyl]hydrazinyl}carbonyl)-5-methylbenzoic acid Not in list C24H28N2O6 O=C(O)c1cc(C)cc(c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C InChI=1/C24H28N2O6/c1-13-10-15(12-16(11-13)23(30)31)22(29)26(24(3,4)5)25-21(28)17-6-7-19-20(14(17)2)18(27)8-9-32-19/h6-7,10-12,18,27H,8-9H2,1-5H3,(H,25,28)(H,30,31) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is a metabolite of the substance 3-({1-tert-butyl-2-[(4-hydroxy-5-methyl-3,4-dihydro-2H-chromen-6-yl)carbonyl]hydrazinyl}carbonyl)-5-methylbenzoic acid 3-({1-tert-butyl-2-[(4-hydroxy-5-methyl-3,4-dihydro-2H-chromen-6-yl)carbonyl]hydrazinyl}carbonyl)-5-methylbenzoic acid Not in list C24H28N2O6 O=C(O)c1cc(C)cc(c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C InChI=1/C24H28N2O6/c1-13-10-15(12-16(11-13)23(30)31)22(29)26(24(3,4)5)25-21(28)17-6-7-19-20(14(17)2)18(27)8-9-32-19/h6-7,10-12,18,27H,8-9H2,1-5H3,(H,25,28)(H,30,31) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is a metabolite of the substance 3-({1-tert-butyl-2-[(4-hydroxy-5-methyl-3,4-dihydro-2H-chromen-6-yl)carbonyl]hydrazinyl}carbonyl)-5-methylbenzoic acid 3-({1-tert-butyl-2-[(4-hydroxy-5-methyl-3,4-dihydro-2H-chromen-6-yl)carbonyl]hydrazinyl}carbonyl)-5-methylbenzoic acid Not in list C24H28N2O6 O=C(O)c1cc(C)cc(c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C InChI=1/C24H28N2O6/c1-13-10-15(12-16(11-13)23(30)31)22(29)26(24(3,4)5)25-21(28)17-6-7-19-20(14(17)2)18(27)8-9-32-19/h6-7,10-12,18,27H,8-9H2,1-5H3,(H,25,28)(H,30,31) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is a metabolite of the substance 3-({1-tert-butyl-2-[(4-hydroxy-5-methyl-3,4-dihydro-2H-chromen-6-yl)carbonyl]hydrazinyl}carbonyl)-5-methylbenzoic acid 3-({1-tert-butyl-2-[(4-hydroxy-5-methyl-3,4-dihydro-2H-chromen-6-yl)carbonyl]hydrazinyl}carbonyl)-5-methylbenzoic acid Not in list C24H28N2O6 O=C(O)c1cc(C)cc(c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C InChI=1/C24H28N2O6/c1-13-10-15(12-16(11-13)23(30)31)22(29)26(24(3,4)5)25-21(28)17-6-7-19-20(14(17)2)18(27)8-9-32-19/h6-7,10-12,18,27H,8-9H2,1-5H3,(H,25,28)(H,30,31) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chromafenozide 143807-66-3 single chemical entity Component is a metabolite of the substance 3-({1-tert-butyl-2-[(4-hydroxy-5-methyl-3,4-dihydro-2H-chromen-6-yl)carbonyl]hydrazinyl}carbonyl)-5-methylbenzoic acid 3-({1-tert-butyl-2-[(4-hydroxy-5-methyl-3,4-dihydro-2H-chromen-6-yl)carbonyl]hydrazinyl}carbonyl)-5-methylbenzoic acid Not in list C24H28N2O6 O=C(O)c1cc(C)cc(c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C InChI=1/C24H28N2O6/c1-13-10-15(12-16(11-13)23(30)31)22(29)26(24(3,4)5)25-21(28)17-6-7-19-20(14(17)2)18(27)8-9-32-19/h6-7,10-12,18,27H,8-9H2,1-5H3,(H,25,28)(H,30,31) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Hungary Chromafenozide 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide. 13Dec2013 2013 doi:10.2903/j.efsa.2013.3461
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 472 (Genetic Toxicology: Escherichia coli, Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes without Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 472 (Genetic Toxicology: Escherichia coli, Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes without Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 472 (Genetic Toxicology: Escherichia coli, Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 472 (Genetic Toxicology: Escherichia coli, Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes with Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 472 (Genetic Toxicology: Escherichia coli, Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes with Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 472 (Genetic Toxicology: Escherichia coli, Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative no information RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Negative no information RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent no treatment without Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent no treatment with Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 472 (Genetic Toxicology: Escherichia coli, Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) K12 Not reported no data without Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro No guideline available Not reported Not applicable Acceptable Klebsiella pneumoniae (as organism) Not reported Not reported yes, concurrent no treatment without Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro No guideline available Not reported Not applicable Acceptable Citrobacter (as organism) Not reported Not reported yes, concurrent no treatment without Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair SOS/umu test in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) PQ37 Not reported no data without Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair SOS/umu test in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) PQ37 Not reported no data with Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Rat (as animal) Sprague-Dawley 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Rat (as animal) Sprague-Dawley 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Rat (as animal) Sprague-Dawley 10 Male/Female oral: gavage 12.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 12 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable House mouse (as animal) Swiss Male/Female Not reported yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration dominant lethal assay in vivo According to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) No Acceptable House mouse (as animal) NMRI 40 Male oral: gavage yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration dominant lethal assay in vivo According to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) No Acceptable House mouse (as animal) Swiss Male oral: gavage no data not applicable Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration dominant lethal assay in vivo According to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) No Acceptable House mouse (as animal) Swiss Male intraperitoneal no data not applicable Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI genome mutation Drosophila SLRL test in vivo Equivalent or similar to OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster) No data Acceptable Drosophila melanogaster (as animal) Not reported Male Not reported no data not applicable Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Chlormequat chloride 213-666-4 999-81-5 single chemical entity Component is identical to the substance Chlormequat chloride 213-666-4 999-81-5 2-Chloroethyl(trimethyl)azanium;chloride Chlormequat C5H13Cl2N C[N+](C)(C)CCCl.[Cl-] InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration dominant lethal assay in vivo No guideline available Not reported Not applicable Acceptable Drosophila melanogaster (as animal) Not reported Male Not reported no data not applicable Negative RMS: The United Kingdom Chlormequat-chloride 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride) 25Feb2009 2009 doi:10.2903/j.efsa.2009.179r
+Cyflumetofen 400882-07-7 single chemical entity Component is identical to the substance Cyflumetofen 400882-07-7 2-methoxyethyl 2-(4-tert-butylphenyl)-2-cyano-3-oxo-3-[2-(trifluoromethyl)phenyl]propanoate Cyflumetofen C24H24F3NO4 CC(C)(C)C1=CC=C(C=C1)C(C#N)(C(=O)C2=CC=CC=C2C(F)(F)F)C(=O)OCCOC InChI=1S/C24H24F3NO4/c1-22(2,3)16-9-11-17(12-10-16)23(15-28,21(30)32-14-13-31-4)20(29)18-7-5-6-8-19(18)24(25,26)27/h5-12H,13-14H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Cyflumetofen (OK-5101) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen 23Jan2012 2012 doi:10.2903/j.efsa.2012.2504
+Cyflumetofen 400882-07-7 single chemical entity Component is identical to the substance Cyflumetofen 400882-07-7 2-methoxyethyl 2-(4-tert-butylphenyl)-2-cyano-3-oxo-3-[2-(trifluoromethyl)phenyl]propanoate Cyflumetofen C24H24F3NO4 CC(C)(C)C1=CC=C(C=C1)C(C#N)(C(=O)C2=CC=CC=C2C(F)(F)F)C(=O)OCCOC InChI=1S/C24H24F3NO4/c1-22(2,3)16-9-11-17(12-10-16)23(15-28,21(30)32-14-13-31-4)20(29)18-7-5-6-8-19(18)24(25,26)27/h5-12H,13-14H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Cyflumetofen (OK-5101) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen 23Jan2012 2012 doi:10.2903/j.efsa.2012.2504
+Cyflumetofen 400882-07-7 single chemical entity Component is identical to the substance Cyflumetofen 400882-07-7 2-methoxyethyl 2-(4-tert-butylphenyl)-2-cyano-3-oxo-3-[2-(trifluoromethyl)phenyl]propanoate Cyflumetofen C24H24F3NO4 CC(C)(C)C1=CC=C(C=C1)C(C#N)(C(=O)C2=CC=CC=C2C(F)(F)F)C(=O)OCCOC InChI=1S/C24H24F3NO4/c1-22(2,3)16-9-11-17(12-10-16)23(15-28,21(30)32-14-13-31-4)20(29)18-7-5-6-8-19(18)24(25,26)27/h5-12H,13-14H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Cyflumetofen (OK-5101) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen 23Jan2012 2012 doi:10.2903/j.efsa.2012.2504
+Cyflumetofen 400882-07-7 single chemical entity Component is identical to the substance Cyflumetofen 400882-07-7 2-methoxyethyl 2-(4-tert-butylphenyl)-2-cyano-3-oxo-3-[2-(trifluoromethyl)phenyl]propanoate Cyflumetofen C24H24F3NO4 CC(C)(C)C1=CC=C(C=C1)C(C#N)(C(=O)C2=CC=CC=C2C(F)(F)F)C(=O)OCCOC InChI=1S/C24H24F3NO4/c1-22(2,3)16-9-11-17(12-10-16)23(15-28,21(30)32-14-13-31-4)20(29)18-7-5-6-8-19(18)24(25,26)27/h5-12H,13-14H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Cyflumetofen (OK-5101) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen 23Jan2012 2012 doi:10.2903/j.efsa.2012.2504
+Cyflumetofen 400882-07-7 single chemical entity Component is identical to the substance Cyflumetofen 400882-07-7 2-methoxyethyl 2-(4-tert-butylphenyl)-2-cyano-3-oxo-3-[2-(trifluoromethyl)phenyl]propanoate Cyflumetofen C24H24F3NO4 CC(C)(C)C1=CC=C(C=C1)C(C#N)(C(=O)C2=CC=CC=C2C(F)(F)F)C(=O)OCCOC InChI=1S/C24H24F3NO4/c1-22(2,3)16-9-11-17(12-10-16)23(15-28,21(30)32-14-13-31-4)20(29)18-7-5-6-8-19(18)24(25,26)27/h5-12H,13-14H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Cyflumetofen (OK-5101) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen 23Jan2012 2012 doi:10.2903/j.efsa.2012.2504
+Cyflumetofen 400882-07-7 single chemical entity Component is identical to the substance Cyflumetofen 400882-07-7 2-methoxyethyl 2-(4-tert-butylphenyl)-2-cyano-3-oxo-3-[2-(trifluoromethyl)phenyl]propanoate Cyflumetofen C24H24F3NO4 CC(C)(C)C1=CC=C(C=C1)C(C#N)(C(=O)C2=CC=CC=C2C(F)(F)F)C(=O)OCCOC InChI=1S/C24H24F3NO4/c1-22(2,3)16-9-11-17(12-10-16)23(15-28,21(30)32-14-13-31-4)20(29)18-7-5-6-8-19(18)24(25,26)27/h5-12H,13-14H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Cyflumetofen (OK-5101) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen 23Jan2012 2012 doi:10.2903/j.efsa.2012.2504
+Cyflumetofen 400882-07-7 single chemical entity Component is identical to the substance Cyflumetofen 400882-07-7 2-methoxyethyl 2-(4-tert-butylphenyl)-2-cyano-3-oxo-3-[2-(trifluoromethyl)phenyl]propanoate Cyflumetofen C24H24F3NO4 CC(C)(C)C1=CC=C(C=C1)C(C#N)(C(=O)C2=CC=CC=C2C(F)(F)F)C(=O)OCCOC InChI=1S/C24H24F3NO4/c1-22(2,3)16-9-11-17(12-10-16)23(15-28,21(30)32-14-13-31-4)20(29)18-7-5-6-8-19(18)24(25,26)27/h5-12H,13-14H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Cyflumetofen (OK-5101) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen 23Jan2012 2012 doi:10.2903/j.efsa.2012.2504
+Cyflumetofen 400882-07-7 single chemical entity Component is identical to the substance Cyflumetofen 400882-07-7 2-methoxyethyl 2-(4-tert-butylphenyl)-2-cyano-3-oxo-3-[2-(trifluoromethyl)phenyl]propanoate Cyflumetofen C24H24F3NO4 CC(C)(C)C1=CC=C(C=C1)C(C#N)(C(=O)C2=CC=CC=C2C(F)(F)F)C(=O)OCCOC InChI=1S/C24H24F3NO4/c1-22(2,3)16-9-11-17(12-10-16)23(15-28,21(30)32-14-13-31-4)20(29)18-7-5-6-8-19(18)24(25,26)27/h5-12H,13-14H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Cyflumetofen (OK-5101) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen 23Jan2012 2012 doi:10.2903/j.efsa.2012.2504
+Cyflumetofen 400882-07-7 single chemical entity Component is identical to the substance Cyflumetofen 400882-07-7 2-methoxyethyl 2-(4-tert-butylphenyl)-2-cyano-3-oxo-3-[2-(trifluoromethyl)phenyl]propanoate Cyflumetofen C24H24F3NO4 CC(C)(C)C1=CC=C(C=C1)C(C#N)(C(=O)C2=CC=CC=C2C(F)(F)F)C(=O)OCCOC InChI=1S/C24H24F3NO4/c1-22(2,3)16-9-11-17(12-10-16)23(15-28,21(30)32-14-13-31-4)20(29)18-7-5-6-8-19(18)24(25,26)27/h5-12H,13-14H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Cyflumetofen (OK-5101) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen 23Jan2012 2012 doi:10.2903/j.efsa.2012.2504
+Cyflumetofen 400882-07-7 single chemical entity Component is identical to the substance Cyflumetofen 400882-07-7 2-methoxyethyl 2-(4-tert-butylphenyl)-2-cyano-3-oxo-3-[2-(trifluoromethyl)phenyl]propanoate Cyflumetofen C24H24F3NO4 CC(C)(C)C1=CC=C(C=C1)C(C#N)(C(=O)C2=CC=CC=C2C(F)(F)F)C(=O)OCCOC InChI=1S/C24H24F3NO4/c1-22(2,3)16-9-11-17(12-10-16)23(15-28,21(30)32-14-13-31-4)20(29)18-7-5-6-8-19(18)24(25,26)27/h5-12H,13-14H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Cyflumetofen (OK-5101) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen 23Jan2012 2012 doi:10.2903/j.efsa.2012.2504
+Cyflumetofen 400882-07-7 single chemical entity Component is identical to the substance Cyflumetofen 400882-07-7 2-methoxyethyl 2-(4-tert-butylphenyl)-2-cyano-3-oxo-3-[2-(trifluoromethyl)phenyl]propanoate Cyflumetofen C24H24F3NO4 CC(C)(C)C1=CC=C(C=C1)C(C#N)(C(=O)C2=CC=CC=C2C(F)(F)F)C(=O)OCCOC InChI=1S/C24H24F3NO4/c1-22(2,3)16-9-11-17(12-10-16)23(15-28,21(30)32-14-13-31-4)20(29)18-7-5-6-8-19(18)24(25,26)27/h5-12H,13-14H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Cyflumetofen (OK-5101) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen 23Jan2012 2012 doi:10.2903/j.efsa.2012.2504
+Cyflumetofen 400882-07-7 single chemical entity Component is identical to the substance Cyflumetofen 400882-07-7 2-methoxyethyl 2-(4-tert-butylphenyl)-2-cyano-3-oxo-3-[2-(trifluoromethyl)phenyl]propanoate Cyflumetofen C24H24F3NO4 CC(C)(C)C1=CC=C(C=C1)C(C#N)(C(=O)C2=CC=CC=C2C(F)(F)F)C(=O)OCCOC InChI=1S/C24H24F3NO4/c1-22(2,3)16-9-11-17(12-10-16)23(15-28,21(30)32-14-13-31-4)20(29)18-7-5-6-8-19(18)24(25,26)27/h5-12H,13-14H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Cyflumetofen (OK-5101) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen 23Jan2012 2012 doi:10.2903/j.efsa.2012.2504
+Cyflumetofen 400882-07-7 single chemical entity Component is identical to the substance Cyflumetofen 400882-07-7 2-methoxyethyl 2-(4-tert-butylphenyl)-2-cyano-3-oxo-3-[2-(trifluoromethyl)phenyl]propanoate Cyflumetofen C24H24F3NO4 CC(C)(C)C1=CC=C(C=C1)C(C#N)(C(=O)C2=CC=CC=C2C(F)(F)F)C(=O)OCCOC InChI=1S/C24H24F3NO4/c1-22(2,3)16-9-11-17(12-10-16)23(15-28,21(30)32-14-13-31-4)20(29)18-7-5-6-8-19(18)24(25,26)27/h5-12H,13-14H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Positive small colonies RMS: The Netherlands Cyflumetofen (OK-5101) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen 23Jan2012 2012 doi:10.2903/j.efsa.2012.2504
+Cyflumetofen 400882-07-7 single chemical entity Component is identical to the substance Cyflumetofen 400882-07-7 2-methoxyethyl 2-(4-tert-butylphenyl)-2-cyano-3-oxo-3-[2-(trifluoromethyl)phenyl]propanoate Cyflumetofen C24H24F3NO4 CC(C)(C)C1=CC=C(C=C1)C(C#N)(C(=O)C2=CC=CC=C2C(F)(F)F)C(=O)OCCOC InChI=1S/C24H24F3NO4/c1-22(2,3)16-9-11-17(12-10-16)23(15-28,21(30)32-14-13-31-4)20(29)18-7-5-6-8-19(18)24(25,26)27/h5-12H,13-14H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative small colonies RMS: The Netherlands Cyflumetofen (OK-5101) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen 23Jan2012 2012 doi:10.2903/j.efsa.2012.2504
+Cyflumetofen 400882-07-7 single chemical entity Component is identical to the substance Cyflumetofen 400882-07-7 2-methoxyethyl 2-(4-tert-butylphenyl)-2-cyano-3-oxo-3-[2-(trifluoromethyl)phenyl]propanoate Cyflumetofen C24H24F3NO4 CC(C)(C)C1=CC=C(C=C1)C(C#N)(C(=O)C2=CC=CC=C2C(F)(F)F)C(=O)OCCOC InChI=1S/C24H24F3NO4/c1-22(2,3)16-9-11-17(12-10-16)23(15-28,21(30)32-14-13-31-4)20(29)18-7-5-6-8-19(18)24(25,26)27/h5-12H,13-14H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 5 Male oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect-toxicokinetic investigations RMS: The Netherlands Cyflumetofen (OK-5101) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen 23Jan2012 2012 doi:10.2903/j.efsa.2012.2504
+Cyflumetofen 400882-07-7 single chemical entity Component is identical to the substance Cyflumetofen 400882-07-7 2-methoxyethyl 2-(4-tert-butylphenyl)-2-cyano-3-oxo-3-[2-(trifluoromethyl)phenyl]propanoate Cyflumetofen C24H24F3NO4 CC(C)(C)C1=CC=C(C=C1)C(C#N)(C(=O)C2=CC=CC=C2C(F)(F)F)C(=O)OCCOC InChI=1S/C24H24F3NO4/c1-22(2,3)16-9-11-17(12-10-16)23(15-28,21(30)32-14-13-31-4)20(29)18-7-5-6-8-19(18)24(25,26)27/h5-12H,13-14H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Wistar 3 Male oral: gavage 16.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The Netherlands Cyflumetofen (OK-5101) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen 23Jan2012 2012 doi:10.2903/j.efsa.2012.2504
+Cyflumetofen 400882-07-7 single chemical entity Component is identical to the substance Cyflumetofen 400882-07-7 2-methoxyethyl 2-(4-tert-butylphenyl)-2-cyano-3-oxo-3-[2-(trifluoromethyl)phenyl]propanoate Cyflumetofen C24H24F3NO4 CC(C)(C)C1=CC=C(C=C1)C(C#N)(C(=O)C2=CC=CC=C2C(F)(F)F)C(=O)OCCOC InChI=1S/C24H24F3NO4/c1-22(2,3)16-9-11-17(12-10-16)23(15-28,21(30)32-14-13-31-4)20(29)18-7-5-6-8-19(18)24(25,26)27/h5-12H,13-14H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Wistar 3 Male oral: gavage 4.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The Netherlands Cyflumetofen (OK-5101) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen 23Jan2012 2012 doi:10.2903/j.efsa.2012.2504
+Cyflumetofen 400882-07-7 single chemical entity Component is a metabolite of the substance Alpha,alpha,alpha-trifluoro-o-toluic acid 207-093-9 433-97-6 2-(trifluoromethyl)benzoic acid Not in list C8H5F3O2 C1=CC=C(C(=C1)C(=O)O)C(F)(F)F InChI=1S/C8H5F3O2/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Cyflumetofen (OK-5101) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen 23Jan2012 2012 doi:10.2903/j.efsa.2012.2504
+Cyflumetofen 400882-07-7 single chemical entity Component is a metabolite of the substance Alpha,alpha,alpha-trifluoro-o-toluic acid 207-093-9 433-97-6 2-(trifluoromethyl)benzoic acid Not in list C8H5F3O2 C1=CC=C(C(=C1)C(=O)O)C(F)(F)F InChI=1S/C8H5F3O2/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Cyflumetofen (OK-5101) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen 23Jan2012 2012 doi:10.2903/j.efsa.2012.2504
+Cyflumetofen 400882-07-7 single chemical entity Component is a metabolite of the substance Alpha,alpha,alpha-trifluoro-o-toluic acid 207-093-9 433-97-6 2-(trifluoromethyl)benzoic acid Not in list C8H5F3O2 C1=CC=C(C(=C1)C(=O)O)C(F)(F)F InChI=1S/C8H5F3O2/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Cyflumetofen (OK-5101) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen 23Jan2012 2012 doi:10.2903/j.efsa.2012.2504
+Cyflumetofen 400882-07-7 single chemical entity Component is a metabolite of the substance Alpha,alpha,alpha-trifluoro-o-toluic acid 207-093-9 433-97-6 2-(trifluoromethyl)benzoic acid Not in list C8H5F3O2 C1=CC=C(C(=C1)C(=O)O)C(F)(F)F InChI=1S/C8H5F3O2/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Cyflumetofen (OK-5101) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen 23Jan2012 2012 doi:10.2903/j.efsa.2012.2504
+Cyflumetofen 400882-07-7 single chemical entity Component is a metabolite of the substance Alpha,alpha,alpha-trifluoro-o-toluic acid 207-093-9 433-97-6 2-(trifluoromethyl)benzoic acid Not in list C8H5F3O2 C1=CC=C(C(=C1)C(=O)O)C(F)(F)F InChI=1S/C8H5F3O2/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Cyflumetofen (OK-5101) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen 23Jan2012 2012 doi:10.2903/j.efsa.2012.2504
+Cyflumetofen 400882-07-7 single chemical entity Component is a metabolite of the substance Alpha,alpha,alpha-trifluoro-o-toluic acid 207-093-9 433-97-6 2-(trifluoromethyl)benzoic acid Not in list C8H5F3O2 C1=CC=C(C(=C1)C(=O)O)C(F)(F)F InChI=1S/C8H5F3O2/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Cyflumetofen (OK-5101) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen 23Jan2012 2012 doi:10.2903/j.efsa.2012.2504
+Cyflumetofen 400882-07-7 single chemical entity Component is a metabolite of the substance Alpha,alpha,alpha-trifluoro-o-toluic acid 207-093-9 433-97-6 2-(trifluoromethyl)benzoic acid Not in list C8H5F3O2 C1=CC=C(C(=C1)C(=O)O)C(F)(F)F InChI=1S/C8H5F3O2/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Cyflumetofen (OK-5101) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen 23Jan2012 2012 doi:10.2903/j.efsa.2012.2504
+Cyflumetofen 400882-07-7 single chemical entity Component is a metabolite of the substance Alpha,alpha,alpha-trifluoro-o-toluic acid 207-093-9 433-97-6 2-(trifluoromethyl)benzoic acid Not in list C8H5F3O2 C1=CC=C(C(=C1)C(=O)O)C(F)(F)F InChI=1S/C8H5F3O2/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Cyflumetofen (OK-5101) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen 23Jan2012 2012 doi:10.2903/j.efsa.2012.2504
+Cyflumetofen 400882-07-7 single chemical entity Component is a metabolite of the substance Alpha,alpha,alpha-trifluoro-o-toluic acid 207-093-9 433-97-6 2-(trifluoromethyl)benzoic acid Not in list C8H5F3O2 C1=CC=C(C(=C1)C(=O)O)C(F)(F)F InChI=1S/C8H5F3O2/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Cyflumetofen (OK-5101) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen 23Jan2012 2012 doi:10.2903/j.efsa.2012.2504
+Cyflumetofen 400882-07-7 single chemical entity Component is a metabolite of the substance Alpha,alpha,alpha-trifluoro-o-toluic acid 207-093-9 433-97-6 2-(trifluoromethyl)benzoic acid Not in list C8H5F3O2 C1=CC=C(C(=C1)C(=O)O)C(F)(F)F InChI=1S/C8H5F3O2/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Cyflumetofen (OK-5101) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen 23Jan2012 2012 doi:10.2903/j.efsa.2012.2504
+Cyflumetofen 400882-07-7 single chemical entity Component is a metabolite of the substance Alpha,alpha,alpha-trifluoro-o-toluic acid 207-093-9 433-97-6 2-(trifluoromethyl)benzoic acid Not in list C8H5F3O2 C1=CC=C(C(=C1)C(=O)O)C(F)(F)F InChI=1S/C8H5F3O2/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Cyflumetofen (OK-5101) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen 23Jan2012 2012 doi:10.2903/j.efsa.2012.2504
+Cyflumetofen 400882-07-7 single chemical entity Component is a metabolite of the substance Alpha,alpha,alpha-trifluoro-o-toluic acid 207-093-9 433-97-6 2-(trifluoromethyl)benzoic acid Not in list C8H5F3O2 C1=CC=C(C(=C1)C(=O)O)C(F)(F)F InChI=1S/C8H5F3O2/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Cyflumetofen (OK-5101) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen 23Jan2012 2012 doi:10.2903/j.efsa.2012.2504
+Cyflumetofen 400882-07-7 single chemical entity Component is a metabolite of the substance Alpha,alpha,alpha-trifluoro-o-toluic acid 207-093-9 433-97-6 2-(trifluoromethyl)benzoic acid Not in list C8H5F3O2 C1=CC=C(C(=C1)C(=O)O)C(F)(F)F InChI=1S/C8H5F3O2/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Positive small colonies RMS: The Netherlands Cyflumetofen (OK-5101) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen 23Jan2012 2012 doi:10.2903/j.efsa.2012.2504
+Cyflumetofen 400882-07-7 single chemical entity Component is a metabolite of the substance Alpha,alpha,alpha-trifluoro-o-toluic acid 207-093-9 433-97-6 2-(trifluoromethyl)benzoic acid Not in list C8H5F3O2 C1=CC=C(C(=C1)C(=O)O)C(F)(F)F InChI=1S/C8H5F3O2/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Positive large colonies RMS: The Netherlands Cyflumetofen (OK-5101) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen 23Jan2012 2012 doi:10.2903/j.efsa.2012.2504
+Cyflumetofen 400882-07-7 single chemical entity Component is a metabolite of the substance Alpha,alpha,alpha-trifluoro-o-toluic acid 207-093-9 433-97-6 2-(trifluoromethyl)benzoic acid Not in list C8H5F3O2 C1=CC=C(C(=C1)C(=O)O)C(F)(F)F InChI=1S/C8H5F3O2/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative small colonies RMS: The Netherlands Cyflumetofen (OK-5101) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen 23Jan2012 2012 doi:10.2903/j.efsa.2012.2504
+Cyflumetofen 400882-07-7 single chemical entity Component is a metabolite of the substance Alpha,alpha,alpha-trifluoro-o-toluic acid 207-093-9 433-97-6 2-(trifluoromethyl)benzoic acid Not in list C8H5F3O2 C1=CC=C(C(=C1)C(=O)O)C(F)(F)F InChI=1S/C8H5F3O2/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative large colonies RMS: The Netherlands Cyflumetofen (OK-5101) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen 23Jan2012 2012 doi:10.2903/j.efsa.2012.2504
+Cyflumetofen 400882-07-7 single chemical entity Component is a metabolite of the substance Alpha,alpha,alpha-trifluoro-o-toluic acid 207-093-9 433-97-6 2-(trifluoromethyl)benzoic acid Not in list C8H5F3O2 C1=CC=C(C(=C1)C(=O)O)C(F)(F)F InChI=1S/C8H5F3O2/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Wistar 3 Male oral: gavage 4.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The Netherlands Cyflumetofen (OK-5101) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen 23Jan2012 2012 doi:10.2903/j.efsa.2012.2504
+Cyflumetofen 400882-07-7 single chemical entity Component is a metabolite of the substance Alpha,alpha,alpha-trifluoro-o-toluic acid 207-093-9 433-97-6 2-(trifluoromethyl)benzoic acid Not in list C8H5F3O2 C1=CC=C(C(=C1)C(=O)O)C(F)(F)F InChI=1S/C8H5F3O2/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Wistar 3 Male oral: gavage 16.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The Netherlands Cyflumetofen (OK-5101) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen 23Jan2012 2012 doi:10.2903/j.efsa.2012.2504
+Cyflumetofen 400882-07-7 single chemical entity Component is a metabolite of the substance 2-(Trifluoromethyl) benzamide 206-637-2 360-64-5 2-(trifluoromethyl)benzamide Not in list C8H6F3NO C1=CC=C(C(=C1)C(=O)N)C(F)(F)F InChI=1S/C8H6F3NO/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H2,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Positive RMS: The Netherlands Cyflumetofen (OK-5101) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen 23Jan2012 2012 doi:10.2903/j.efsa.2012.2504
+Cyflumetofen 400882-07-7 single chemical entity Component is a metabolite of the substance 2-(Trifluoromethyl) benzamide 206-637-2 360-64-5 2-(trifluoromethyl)benzamide Not in list C8H6F3NO C1=CC=C(C(=C1)C(=O)N)C(F)(F)F InChI=1S/C8H6F3NO/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H2,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Cyflumetofen (OK-5101) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen 23Jan2012 2012 doi:10.2903/j.efsa.2012.2504
+Cyflumetofen 400882-07-7 single chemical entity Component is a metabolite of the substance 2-(Trifluoromethyl) benzamide 206-637-2 360-64-5 2-(trifluoromethyl)benzamide Not in list C8H6F3NO C1=CC=C(C(=C1)C(=O)N)C(F)(F)F InChI=1S/C8H6F3NO/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H2,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Cyflumetofen (OK-5101) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen 23Jan2012 2012 doi:10.2903/j.efsa.2012.2504
+Cyflumetofen 400882-07-7 single chemical entity Component is a metabolite of the substance 2-(Trifluoromethyl) benzamide 206-637-2 360-64-5 2-(trifluoromethyl)benzamide Not in list C8H6F3NO C1=CC=C(C(=C1)C(=O)N)C(F)(F)F InChI=1S/C8H6F3NO/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H2,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Cyflumetofen (OK-5101) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen 23Jan2012 2012 doi:10.2903/j.efsa.2012.2504
+Cyflumetofen 400882-07-7 single chemical entity Component is a metabolite of the substance 2-(Trifluoromethyl) benzamide 206-637-2 360-64-5 2-(trifluoromethyl)benzamide Not in list C8H6F3NO C1=CC=C(C(=C1)C(=O)N)C(F)(F)F InChI=1S/C8H6F3NO/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H2,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Cyflumetofen (OK-5101) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen 23Jan2012 2012 doi:10.2903/j.efsa.2012.2504
+Cyflumetofen 400882-07-7 single chemical entity Component is a metabolite of the substance 2-(Trifluoromethyl) benzamide 206-637-2 360-64-5 2-(trifluoromethyl)benzamide Not in list C8H6F3NO C1=CC=C(C(=C1)C(=O)N)C(F)(F)F InChI=1S/C8H6F3NO/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H2,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Cyflumetofen (OK-5101) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen 23Jan2012 2012 doi:10.2903/j.efsa.2012.2504
+Cyflumetofen 400882-07-7 single chemical entity Component is a metabolite of the substance 2-(Trifluoromethyl) benzamide 206-637-2 360-64-5 2-(trifluoromethyl)benzamide Not in list C8H6F3NO C1=CC=C(C(=C1)C(=O)N)C(F)(F)F InChI=1S/C8H6F3NO/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H2,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Cyflumetofen (OK-5101) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen 23Jan2012 2012 doi:10.2903/j.efsa.2012.2504
+Cyflumetofen 400882-07-7 single chemical entity Component is a metabolite of the substance 2-(Trifluoromethyl) benzamide 206-637-2 360-64-5 2-(trifluoromethyl)benzamide Not in list C8H6F3NO C1=CC=C(C(=C1)C(=O)N)C(F)(F)F InChI=1S/C8H6F3NO/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H2,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Positive RMS: The Netherlands Cyflumetofen (OK-5101) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen 23Jan2012 2012 doi:10.2903/j.efsa.2012.2504
+Cyflumetofen 400882-07-7 single chemical entity Component is a metabolite of the substance 2-(Trifluoromethyl) benzamide 206-637-2 360-64-5 2-(trifluoromethyl)benzamide Not in list C8H6F3NO C1=CC=C(C(=C1)C(=O)N)C(F)(F)F InChI=1S/C8H6F3NO/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H2,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Cyflumetofen (OK-5101) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen 23Jan2012 2012 doi:10.2903/j.efsa.2012.2504
+Cyflumetofen 400882-07-7 single chemical entity Component is a metabolite of the substance 2-(Trifluoromethyl) benzamide 206-637-2 360-64-5 2-(trifluoromethyl)benzamide Not in list C8H6F3NO C1=CC=C(C(=C1)C(=O)N)C(F)(F)F InChI=1S/C8H6F3NO/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H2,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Cyflumetofen (OK-5101) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen 23Jan2012 2012 doi:10.2903/j.efsa.2012.2504
+Cyflumetofen 400882-07-7 single chemical entity Component is a metabolite of the substance 2-(Trifluoromethyl) benzamide 206-637-2 360-64-5 2-(trifluoromethyl)benzamide Not in list C8H6F3NO C1=CC=C(C(=C1)C(=O)N)C(F)(F)F InChI=1S/C8H6F3NO/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H2,12,13) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Cyflumetofen (OK-5101) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen 23Jan2012 2012 doi:10.2903/j.efsa.2012.2504
+Cyflumetofen 400882-07-7 single chemical entity Component is a metabolite of the substance 2-(Trifluoromethyl) benzamide 206-637-2 360-64-5 2-(trifluoromethyl)benzamide Not in list C8H6F3NO C1=CC=C(C(=C1)C(=O)N)C(F)(F)F InChI=1S/C8H6F3NO/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H2,12,13) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Cyflumetofen (OK-5101) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen 23Jan2012 2012 doi:10.2903/j.efsa.2012.2504
+Cyflumetofen 400882-07-7 single chemical entity Component is a metabolite of the substance 2-(Trifluoromethyl) benzamide 206-637-2 360-64-5 2-(trifluoromethyl)benzamide Not in list C8H6F3NO C1=CC=C(C(=C1)C(=O)N)C(F)(F)F InChI=1S/C8H6F3NO/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H2,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative large colonies RMS: The Netherlands Cyflumetofen (OK-5101) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen 23Jan2012 2012 doi:10.2903/j.efsa.2012.2504
+Cyflumetofen 400882-07-7 single chemical entity Component is a metabolite of the substance 2-(Trifluoromethyl) benzamide 206-637-2 360-64-5 2-(trifluoromethyl)benzamide Not in list C8H6F3NO C1=CC=C(C(=C1)C(=O)N)C(F)(F)F InChI=1S/C8H6F3NO/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H2,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative small colonies RMS: The Netherlands Cyflumetofen (OK-5101) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen 23Jan2012 2012 doi:10.2903/j.efsa.2012.2504
+Cyflumetofen 400882-07-7 single chemical entity Component is a metabolite of the substance 2-(Trifluoromethyl) benzamide 206-637-2 360-64-5 2-(trifluoromethyl)benzamide Not in list C8H6F3NO C1=CC=C(C(=C1)C(=O)N)C(F)(F)F InChI=1S/C8H6F3NO/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H2,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: The Netherlands Cyflumetofen (OK-5101) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen 23Jan2012 2012 doi:10.2903/j.efsa.2012.2504
+Cyflumetofen 400882-07-7 single chemical entity Component is a metabolite of the substance 2-(Trifluoromethyl) benzamide 206-637-2 360-64-5 2-(trifluoromethyl)benzamide Not in list C8H6F3NO C1=CC=C(C(=C1)C(=O)N)C(F)(F)F InChI=1S/C8H6F3NO/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H2,12,13) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Wistar 3 Male oral: gavage 4.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The Netherlands Cyflumetofen (OK-5101) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen 23Jan2012 2012 doi:10.2903/j.efsa.2012.2504
+Cyflumetofen 400882-07-7 single chemical entity Component is a metabolite of the substance 2-(Trifluoromethyl) benzamide 206-637-2 360-64-5 2-(trifluoromethyl)benzamide Not in list C8H6F3NO C1=CC=C(C(=C1)C(=O)N)C(F)(F)F InChI=1S/C8H6F3NO/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H2,12,13) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Wistar 3 Male oral: gavage 16.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The Netherlands Cyflumetofen (OK-5101) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen 23Jan2012 2012 doi:10.2903/j.efsa.2012.2504
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is identical to the substance Carfentrazone-ethyl 603-291-8 128639-02-1 ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate Carfentrazone-ethyl C15H14Cl2F3N3O3 CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is identical to the substance Carfentrazone-ethyl 603-291-8 128639-02-1 ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate Carfentrazone-ethyl C15H14Cl2F3N3O3 CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is identical to the substance Carfentrazone-ethyl 603-291-8 128639-02-1 ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate Carfentrazone-ethyl C15H14Cl2F3N3O3 CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is identical to the substance Carfentrazone-ethyl 603-291-8 128639-02-1 ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate Carfentrazone-ethyl C15H14Cl2F3N3O3 CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is identical to the substance Carfentrazone-ethyl 603-291-8 128639-02-1 ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate Carfentrazone-ethyl C15H14Cl2F3N3O3 CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is identical to the substance Carfentrazone-ethyl 603-291-8 128639-02-1 ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate Carfentrazone-ethyl C15H14Cl2F3N3O3 CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is identical to the substance Carfentrazone-ethyl 603-291-8 128639-02-1 ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate Carfentrazone-ethyl C15H14Cl2F3N3O3 CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is identical to the substance Carfentrazone-ethyl 603-291-8 128639-02-1 ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate Carfentrazone-ethyl C15H14Cl2F3N3O3 CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is identical to the substance Carfentrazone-ethyl 603-291-8 128639-02-1 ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate Carfentrazone-ethyl C15H14Cl2F3N3O3 CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is identical to the substance Carfentrazone-ethyl 603-291-8 128639-02-1 ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate Carfentrazone-ethyl C15H14Cl2F3N3O3 CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is identical to the substance Carfentrazone-ethyl 603-291-8 128639-02-1 ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate Carfentrazone-ethyl C15H14Cl2F3N3O3 CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is identical to the substance Carfentrazone-ethyl 603-291-8 128639-02-1 ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate Carfentrazone-ethyl C15H14Cl2F3N3O3 CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is identical to the substance Carfentrazone-ethyl 603-291-8 128639-02-1 ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate Carfentrazone-ethyl C15H14Cl2F3N3O3 CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is identical to the substance Carfentrazone-ethyl 603-291-8 128639-02-1 ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate Carfentrazone-ethyl C15H14Cl2F3N3O3 CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is identical to the substance Carfentrazone-ethyl 603-291-8 128639-02-1 ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate Carfentrazone-ethyl C15H14Cl2F3N3O3 CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is identical to the substance Carfentrazone-ethyl 603-291-8 128639-02-1 ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate Carfentrazone-ethyl C15H14Cl2F3N3O3 CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is identical to the substance Carfentrazone-ethyl 603-291-8 128639-02-1 ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate Carfentrazone-ethyl C15H14Cl2F3N3O3 CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is identical to the substance Carfentrazone-ethyl 603-291-8 128639-02-1 ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate Carfentrazone-ethyl C15H14Cl2F3N3O3 CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is identical to the substance Carfentrazone-ethyl 603-291-8 128639-02-1 ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate Carfentrazone-ethyl C15H14Cl2F3N3O3 CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is identical to the substance Carfentrazone-ethyl 603-291-8 128639-02-1 ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate Carfentrazone-ethyl C15H14Cl2F3N3O3 CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is identical to the substance Carfentrazone-ethyl 603-291-8 128639-02-1 ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate Carfentrazone-ethyl C15H14Cl2F3N3O3 CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is identical to the substance Carfentrazone-ethyl 603-291-8 128639-02-1 ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate Carfentrazone-ethyl C15H14Cl2F3N3O3 CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is identical to the substance Carfentrazone-ethyl 603-291-8 128639-02-1 ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate Carfentrazone-ethyl C15H14Cl2F3N3O3 CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is identical to the substance Carfentrazone-ethyl 603-291-8 128639-02-1 ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate Carfentrazone-ethyl C15H14Cl2F3N3O3 CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is identical to the substance Carfentrazone-ethyl 603-291-8 128639-02-1 ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate Carfentrazone-ethyl C15H14Cl2F3N3O3 CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is identical to the substance Carfentrazone-ethyl 603-291-8 128639-02-1 ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate Carfentrazone-ethyl C15H14Cl2F3N3O3 CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is identical to the substance Carfentrazone-ethyl 603-291-8 128639-02-1 ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate Carfentrazone-ethyl C15H14Cl2F3N3O3 CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is identical to the substance Carfentrazone-ethyl 603-291-8 128639-02-1 ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate Carfentrazone-ethyl C15H14Cl2F3N3O3 CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is identical to the substance Carfentrazone-ethyl 603-291-8 128639-02-1 ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate Carfentrazone-ethyl C15H14Cl2F3N3O3 CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is identical to the substance Carfentrazone-ethyl 603-291-8 128639-02-1 ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate Carfentrazone-ethyl C15H14Cl2F3N3O3 CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is identical to the substance Carfentrazone-ethyl 603-291-8 128639-02-1 ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate Carfentrazone-ethyl C15H14Cl2F3N3O3 CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is identical to the substance Carfentrazone-ethyl 603-291-8 128639-02-1 ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate Carfentrazone-ethyl C15H14Cl2F3N3O3 CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is identical to the substance Carfentrazone-ethyl 603-291-8 128639-02-1 ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate Carfentrazone-ethyl C15H14Cl2F3N3O3 CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is identical to the substance Carfentrazone-ethyl 603-291-8 128639-02-1 ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate Carfentrazone-ethyl C15H14Cl2F3N3O3 CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is identical to the substance Carfentrazone-ethyl 603-291-8 128639-02-1 ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate Carfentrazone-ethyl C15H14Cl2F3N3O3 CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Positive RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is identical to the substance Carfentrazone-ethyl 603-291-8 128639-02-1 ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate Carfentrazone-ethyl C15H14Cl2F3N3O3 CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is identical to the substance Carfentrazone-ethyl 603-291-8 128639-02-1 ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate Carfentrazone-ethyl C15H14Cl2F3N3O3 CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is identical to the substance Carfentrazone-ethyl 603-291-8 128639-02-1 ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate Carfentrazone-ethyl C15H14Cl2F3N3O3 CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is identical to the substance Carfentrazone-ethyl 603-291-8 128639-02-1 ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate Carfentrazone-ethyl C15H14Cl2F3N3O3 CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Fischer344 5 Male intraperitoneal 4.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is identical to the substance Carfentrazone-ethyl 603-291-8 128639-02-1 ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate Carfentrazone-ethyl C15H14Cl2F3N3O3 CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Fischer344 5 Male intraperitoneal 16.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is identical to the substance Carfentrazone-ethyl 603-291-8 128639-02-1 ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate Carfentrazone-ethyl C15H14Cl2F3N3O3 CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Not reported 10 Male/Female intraperitoneal 48.0000000000 h yes not applicable Negative indirect evidence-systemic toxicity RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is identical to the substance Carfentrazone-ethyl 603-291-8 128639-02-1 ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate Carfentrazone-ethyl C15H14Cl2F3N3O3 CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Not reported 10 Male/Female intraperitoneal 24.0000000000 h yes not applicable Negative indirect evidence-systemic toxicity RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is identical to the substance Carfentrazone-ethyl 603-291-8 128639-02-1 ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate Carfentrazone-ethyl C15H14Cl2F3N3O3 CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Not reported 10 Male/Female intraperitoneal 72.0000000000 h yes not applicable Negative indirect evidence-systemic toxicity RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance (RS)-2-Chloro-3-{2-chloro-5-[4-(difluoromethyl)-4,5-dihydro-3-methyl-5-oxo-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propionic acid 603-289-7 128621-72-7 2-chloro-3-{2-chloro-5-[4- (difluoromethyl)-3-methyl-5-oxo- 1,2,4-triazol-1-yl]-4- fluorophenyl}propanoic acid Not in list C13H10Cl2F3N3O3 CC1=NN(C(=O)N1C(F)F)C2=C(C=C(C(=C2)CC(C(=O)O)Cl)Cl)F InChI=1S/C13H10Cl2F3N3O3/c1-5-19-21(13(24)20(5)12(17)18)10-3-6(2-8(15)11(22)23)7(14)4-9(10)16/h3-4,8,12H,2H2,1H3,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance (RS)-2-Chloro-3-{2-chloro-5-[4-(difluoromethyl)-4,5-dihydro-3-methyl-5-oxo-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propionic acid 603-289-7 128621-72-7 2-chloro-3-{2-chloro-5-[4- (difluoromethyl)-3-methyl-5-oxo- 1,2,4-triazol-1-yl]-4- fluorophenyl}propanoic acid Not in list C13H10Cl2F3N3O3 CC1=NN(C(=O)N1C(F)F)C2=C(C=C(C(=C2)CC(C(=O)O)Cl)Cl)F InChI=1S/C13H10Cl2F3N3O3/c1-5-19-21(13(24)20(5)12(17)18)10-3-6(2-8(15)11(22)23)7(14)4-9(10)16/h3-4,8,12H,2H2,1H3,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance (RS)-2-Chloro-3-{2-chloro-5-[4-(difluoromethyl)-4,5-dihydro-3-methyl-5-oxo-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propionic acid 603-289-7 128621-72-7 2-chloro-3-{2-chloro-5-[4- (difluoromethyl)-3-methyl-5-oxo- 1,2,4-triazol-1-yl]-4- fluorophenyl}propanoic acid Not in list C13H10Cl2F3N3O3 CC1=NN(C(=O)N1C(F)F)C2=C(C=C(C(=C2)CC(C(=O)O)Cl)Cl)F InChI=1S/C13H10Cl2F3N3O3/c1-5-19-21(13(24)20(5)12(17)18)10-3-6(2-8(15)11(22)23)7(14)4-9(10)16/h3-4,8,12H,2H2,1H3,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance (RS)-2-Chloro-3-{2-chloro-5-[4-(difluoromethyl)-4,5-dihydro-3-methyl-5-oxo-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propionic acid 603-289-7 128621-72-7 2-chloro-3-{2-chloro-5-[4- (difluoromethyl)-3-methyl-5-oxo- 1,2,4-triazol-1-yl]-4- fluorophenyl}propanoic acid Not in list C13H10Cl2F3N3O3 CC1=NN(C(=O)N1C(F)F)C2=C(C=C(C(=C2)CC(C(=O)O)Cl)Cl)F InChI=1S/C13H10Cl2F3N3O3/c1-5-19-21(13(24)20(5)12(17)18)10-3-6(2-8(15)11(22)23)7(14)4-9(10)16/h3-4,8,12H,2H2,1H3,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance (RS)-2-Chloro-3-{2-chloro-5-[4-(difluoromethyl)-4,5-dihydro-3-methyl-5-oxo-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propionic acid 603-289-7 128621-72-7 2-chloro-3-{2-chloro-5-[4- (difluoromethyl)-3-methyl-5-oxo- 1,2,4-triazol-1-yl]-4- fluorophenyl}propanoic acid Not in list C13H10Cl2F3N3O3 CC1=NN(C(=O)N1C(F)F)C2=C(C=C(C(=C2)CC(C(=O)O)Cl)Cl)F InChI=1S/C13H10Cl2F3N3O3/c1-5-19-21(13(24)20(5)12(17)18)10-3-6(2-8(15)11(22)23)7(14)4-9(10)16/h3-4,8,12H,2H2,1H3,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance (RS)-2-Chloro-3-{2-chloro-5-[4-(difluoromethyl)-4,5-dihydro-3-methyl-5-oxo-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propionic acid 603-289-7 128621-72-7 2-chloro-3-{2-chloro-5-[4- (difluoromethyl)-3-methyl-5-oxo- 1,2,4-triazol-1-yl]-4- fluorophenyl}propanoic acid Not in list C13H10Cl2F3N3O3 CC1=NN(C(=O)N1C(F)F)C2=C(C=C(C(=C2)CC(C(=O)O)Cl)Cl)F InChI=1S/C13H10Cl2F3N3O3/c1-5-19-21(13(24)20(5)12(17)18)10-3-6(2-8(15)11(22)23)7(14)4-9(10)16/h3-4,8,12H,2H2,1H3,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance (RS)-2-Chloro-3-{2-chloro-5-[4-(difluoromethyl)-4,5-dihydro-3-methyl-5-oxo-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propionic acid 603-289-7 128621-72-7 2-chloro-3-{2-chloro-5-[4- (difluoromethyl)-3-methyl-5-oxo- 1,2,4-triazol-1-yl]-4- fluorophenyl}propanoic acid Not in list C13H10Cl2F3N3O3 CC1=NN(C(=O)N1C(F)F)C2=C(C=C(C(=C2)CC(C(=O)O)Cl)Cl)F InChI=1S/C13H10Cl2F3N3O3/c1-5-19-21(13(24)20(5)12(17)18)10-3-6(2-8(15)11(22)23)7(14)4-9(10)16/h3-4,8,12H,2H2,1H3,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance (RS)-2-Chloro-3-{2-chloro-5-[4-(difluoromethyl)-4,5-dihydro-3-methyl-5-oxo-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propionic acid 603-289-7 128621-72-7 2-chloro-3-{2-chloro-5-[4- (difluoromethyl)-3-methyl-5-oxo- 1,2,4-triazol-1-yl]-4- fluorophenyl}propanoic acid Not in list C13H10Cl2F3N3O3 CC1=NN(C(=O)N1C(F)F)C2=C(C=C(C(=C2)CC(C(=O)O)Cl)Cl)F InChI=1S/C13H10Cl2F3N3O3/c1-5-19-21(13(24)20(5)12(17)18)10-3-6(2-8(15)11(22)23)7(14)4-9(10)16/h3-4,8,12H,2H2,1H3,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance (RS)-2-Chloro-3-{2-chloro-5-[4-(difluoromethyl)-4,5-dihydro-3-methyl-5-oxo-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propionic acid 603-289-7 128621-72-7 2-chloro-3-{2-chloro-5-[4- (difluoromethyl)-3-methyl-5-oxo- 1,2,4-triazol-1-yl]-4- fluorophenyl}propanoic acid Not in list C13H10Cl2F3N3O3 CC1=NN(C(=O)N1C(F)F)C2=C(C=C(C(=C2)CC(C(=O)O)Cl)Cl)F InChI=1S/C13H10Cl2F3N3O3/c1-5-19-21(13(24)20(5)12(17)18)10-3-6(2-8(15)11(22)23)7(14)4-9(10)16/h3-4,8,12H,2H2,1H3,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance (RS)-2-Chloro-3-{2-chloro-5-[4-(difluoromethyl)-4,5-dihydro-3-methyl-5-oxo-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propionic acid 603-289-7 128621-72-7 2-chloro-3-{2-chloro-5-[4- (difluoromethyl)-3-methyl-5-oxo- 1,2,4-triazol-1-yl]-4- fluorophenyl}propanoic acid Not in list C13H10Cl2F3N3O3 CC1=NN(C(=O)N1C(F)F)C2=C(C=C(C(=C2)CC(C(=O)O)Cl)Cl)F InChI=1S/C13H10Cl2F3N3O3/c1-5-19-21(13(24)20(5)12(17)18)10-3-6(2-8(15)11(22)23)7(14)4-9(10)16/h3-4,8,12H,2H2,1H3,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid 2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid Not in list C11H7ClF3O3 O=C(O)c1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F InChI=1/C11H7ClF3N3O3/c1-4-16-18(11(21)17(4)10(14)15)8-2-5(9(19)20)6(12)3-7(8)13/h2-3,10H,1H3,(H,19,20) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid 2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid Not in list C11H7ClF3O3 O=C(O)c1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F InChI=1/C11H7ClF3N3O3/c1-4-16-18(11(21)17(4)10(14)15)8-2-5(9(19)20)6(12)3-7(8)13/h2-3,10H,1H3,(H,19,20) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid 2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid Not in list C11H7ClF3O3 O=C(O)c1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F InChI=1/C11H7ClF3N3O3/c1-4-16-18(11(21)17(4)10(14)15)8-2-5(9(19)20)6(12)3-7(8)13/h2-3,10H,1H3,(H,19,20) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid 2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid Not in list C11H7ClF3O3 O=C(O)c1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F InChI=1/C11H7ClF3N3O3/c1-4-16-18(11(21)17(4)10(14)15)8-2-5(9(19)20)6(12)3-7(8)13/h2-3,10H,1H3,(H,19,20) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid 2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid Not in list C11H7ClF3O3 O=C(O)c1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F InChI=1/C11H7ClF3N3O3/c1-4-16-18(11(21)17(4)10(14)15)8-2-5(9(19)20)6(12)3-7(8)13/h2-3,10H,1H3,(H,19,20) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid 2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid Not in list C11H7ClF3O3 O=C(O)c1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F InChI=1/C11H7ClF3N3O3/c1-4-16-18(11(21)17(4)10(14)15)8-2-5(9(19)20)6(12)3-7(8)13/h2-3,10H,1H3,(H,19,20) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid 2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid Not in list C11H7ClF3O3 O=C(O)c1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F InChI=1/C11H7ClF3N3O3/c1-4-16-18(11(21)17(4)10(14)15)8-2-5(9(19)20)6(12)3-7(8)13/h2-3,10H,1H3,(H,19,20) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid 2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid Not in list C11H7ClF3O3 O=C(O)c1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F InChI=1/C11H7ClF3N3O3/c1-4-16-18(11(21)17(4)10(14)15)8-2-5(9(19)20)6(12)3-7(8)13/h2-3,10H,1H3,(H,19,20) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid 2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid Not in list C11H7ClF3O3 O=C(O)c1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F InChI=1/C11H7ClF3N3O3/c1-4-16-18(11(21)17(4)10(14)15)8-2-5(9(19)20)6(12)3-7(8)13/h2-3,10H,1H3,(H,19,20) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid 2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid Not in list C11H7ClF3O3 O=C(O)c1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F InChI=1/C11H7ClF3N3O3/c1-4-16-18(11(21)17(4)10(14)15)8-2-5(9(19)20)6(12)3-7(8)13/h2-3,10H,1H3,(H,19,20) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid 2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid Not in list C11H7ClF3O3 O=C(O)c1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F InChI=1/C11H7ClF3N3O3/c1-4-16-18(11(21)17(4)10(14)15)8-2-5(9(19)20)6(12)3-7(8)13/h2-3,10H,1H3,(H,19,20) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid 2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid Not in list C11H7ClF3O3 O=C(O)c1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F InChI=1/C11H7ClF3N3O3/c1-4-16-18(11(21)17(4)10(14)15)8-2-5(9(19)20)6(12)3-7(8)13/h2-3,10H,1H3,(H,19,20) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid 2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid Not in list C11H7ClF3O3 O=C(O)c1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F InChI=1/C11H7ClF3N3O3/c1-4-16-18(11(21)17(4)10(14)15)8-2-5(9(19)20)6(12)3-7(8)13/h2-3,10H,1H3,(H,19,20) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid 2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid Not in list C11H7ClF3O3 O=C(O)c1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F InChI=1/C11H7ClF3N3O3/c1-4-16-18(11(21)17(4)10(14)15)8-2-5(9(19)20)6(12)3-7(8)13/h2-3,10H,1H3,(H,19,20) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid 3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid Not in list C13H11ClF3N3O3 O=C(O)CCc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F InChI=1/C13H11ClF3N3O3/c1-6-18-20(13(23)19(6)12(16)17)10-4-7(2-3-11(21)22)8(14)5-9(10)15/h4-5,12H,2-3H2,1H3,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid 3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid Not in list C13H11ClF3N3O3 O=C(O)CCc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F InChI=1/C13H11ClF3N3O3/c1-6-18-20(13(23)19(6)12(16)17)10-4-7(2-3-11(21)22)8(14)5-9(10)15/h4-5,12H,2-3H2,1H3,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid 3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid Not in list C13H11ClF3N3O3 O=C(O)CCc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F InChI=1/C13H11ClF3N3O3/c1-6-18-20(13(23)19(6)12(16)17)10-4-7(2-3-11(21)22)8(14)5-9(10)15/h4-5,12H,2-3H2,1H3,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid 3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid Not in list C13H11ClF3N3O3 O=C(O)CCc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F InChI=1/C13H11ClF3N3O3/c1-6-18-20(13(23)19(6)12(16)17)10-4-7(2-3-11(21)22)8(14)5-9(10)15/h4-5,12H,2-3H2,1H3,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid 3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid Not in list C13H11ClF3N3O3 O=C(O)CCc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F InChI=1/C13H11ClF3N3O3/c1-6-18-20(13(23)19(6)12(16)17)10-4-7(2-3-11(21)22)8(14)5-9(10)15/h4-5,12H,2-3H2,1H3,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid 3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid Not in list C13H11ClF3N3O3 O=C(O)CCc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F InChI=1/C13H11ClF3N3O3/c1-6-18-20(13(23)19(6)12(16)17)10-4-7(2-3-11(21)22)8(14)5-9(10)15/h4-5,12H,2-3H2,1H3,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid 3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid Not in list C13H11ClF3N3O3 O=C(O)CCc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F InChI=1/C13H11ClF3N3O3/c1-6-18-20(13(23)19(6)12(16)17)10-4-7(2-3-11(21)22)8(14)5-9(10)15/h4-5,12H,2-3H2,1H3,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid 3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid Not in list C13H11ClF3N3O3 O=C(O)CCc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F InChI=1/C13H11ClF3N3O3/c1-6-18-20(13(23)19(6)12(16)17)10-4-7(2-3-11(21)22)8(14)5-9(10)15/h4-5,12H,2-3H2,1H3,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid 3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid Not in list C13H11ClF3N3O3 O=C(O)CCc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F InChI=1/C13H11ClF3N3O3/c1-6-18-20(13(23)19(6)12(16)17)10-4-7(2-3-11(21)22)8(14)5-9(10)15/h4-5,12H,2-3H2,1H3,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid 3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid Not in list C13H11ClF3N3O3 O=C(O)CCc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F InChI=1/C13H11ClF3N3O3/c1-6-18-20(13(23)19(6)12(16)17)10-4-7(2-3-11(21)22)8(14)5-9(10)15/h4-5,12H,2-3H2,1H3,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid 3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid Not in list C13H11ClF3N3O3 O=C(O)CCc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F InChI=1/C13H11ClF3N3O3/c1-6-18-20(13(23)19(6)12(16)17)10-4-7(2-3-11(21)22)8(14)5-9(10)15/h4-5,12H,2-3H2,1H3,(H,21,22) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid 3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid Not in list C13H11ClF3N3O3 O=C(O)CCc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F InChI=1/C13H11ClF3N3O3/c1-6-18-20(13(23)19(6)12(16)17)10-4-7(2-3-11(21)22)8(14)5-9(10)15/h4-5,12H,2-3H2,1H3,(H,21,22) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid 3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid Not in list C13H11ClF3N3O3 O=C(O)CCc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F InChI=1/C13H11ClF3N3O3/c1-6-18-20(13(23)19(6)12(16)17)10-4-7(2-3-11(21)22)8(14)5-9(10)15/h4-5,12H,2-3H2,1H3,(H,21,22) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid 3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid Not in list C13H11ClF3N3O3 O=C(O)CCc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F InChI=1/C13H11ClF3N3O3/c1-6-18-20(13(23)19(6)12(16)17)10-4-7(2-3-11(21)22)8(14)5-9(10)15/h4-5,12H,2-3H2,1H3,(H,21,22) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance (2E)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}acrylic acid (2E)-3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}prop-2-enoic acid Not in list C13H9ClF3N3O3 O=C(O)/C=C/c1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F InChI=1/C13H9ClF3N3O3/c1-6-18-20(13(23)19(6)12(16)17)10-4-7(2-3-11(21)22)8(14)5-9(10)15/h2-5,12H,1H3,(H,21,22)/b3-2+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance (2E)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}acrylic acid (2E)-3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}prop-2-enoic acid Not in list C13H9ClF3N3O3 O=C(O)/C=C/c1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F InChI=1/C13H9ClF3N3O3/c1-6-18-20(13(23)19(6)12(16)17)10-4-7(2-3-11(21)22)8(14)5-9(10)15/h2-5,12H,1H3,(H,21,22)/b3-2+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance (2E)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}acrylic acid (2E)-3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}prop-2-enoic acid Not in list C13H9ClF3N3O3 O=C(O)/C=C/c1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F InChI=1/C13H9ClF3N3O3/c1-6-18-20(13(23)19(6)12(16)17)10-4-7(2-3-11(21)22)8(14)5-9(10)15/h2-5,12H,1H3,(H,21,22)/b3-2+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance (2E)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}acrylic acid (2E)-3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}prop-2-enoic acid Not in list C13H9ClF3N3O3 O=C(O)/C=C/c1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F InChI=1/C13H9ClF3N3O3/c1-6-18-20(13(23)19(6)12(16)17)10-4-7(2-3-11(21)22)8(14)5-9(10)15/h2-5,12H,1H3,(H,21,22)/b3-2+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance (2E)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}acrylic acid (2E)-3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}prop-2-enoic acid Not in list C13H9ClF3N3O3 O=C(O)/C=C/c1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F InChI=1/C13H9ClF3N3O3/c1-6-18-20(13(23)19(6)12(16)17)10-4-7(2-3-11(21)22)8(14)5-9(10)15/h2-5,12H,1H3,(H,21,22)/b3-2+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance (2E)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}acrylic acid (2E)-3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}prop-2-enoic acid Not in list C13H9ClF3N3O3 O=C(O)/C=C/c1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F InChI=1/C13H9ClF3N3O3/c1-6-18-20(13(23)19(6)12(16)17)10-4-7(2-3-11(21)22)8(14)5-9(10)15/h2-5,12H,1H3,(H,21,22)/b3-2+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance (2E)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}acrylic acid (2E)-3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}prop-2-enoic acid Not in list C13H9ClF3N3O3 O=C(O)/C=C/c1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F InChI=1/C13H9ClF3N3O3/c1-6-18-20(13(23)19(6)12(16)17)10-4-7(2-3-11(21)22)8(14)5-9(10)15/h2-5,12H,1H3,(H,21,22)/b3-2+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance (2E)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}acrylic acid (2E)-3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}prop-2-enoic acid Not in list C13H9ClF3N3O3 O=C(O)/C=C/c1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F InChI=1/C13H9ClF3N3O3/c1-6-18-20(13(23)19(6)12(16)17)10-4-7(2-3-11(21)22)8(14)5-9(10)15/h2-5,12H,1H3,(H,21,22)/b3-2+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance (2E)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}acrylic acid (2E)-3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}prop-2-enoic acid Not in list C13H9ClF3N3O3 O=C(O)/C=C/c1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F InChI=1/C13H9ClF3N3O3/c1-6-18-20(13(23)19(6)12(16)17)10-4-7(2-3-11(21)22)8(14)5-9(10)15/h2-5,12H,1H3,(H,21,22)/b3-2+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance (2E)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}acrylic acid (2E)-3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}prop-2-enoic acid Not in list C13H9ClF3N3O3 O=C(O)/C=C/c1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F InChI=1/C13H9ClF3N3O3/c1-6-18-20(13(23)19(6)12(16)17)10-4-7(2-3-11(21)22)8(14)5-9(10)15/h2-5,12H,1H3,(H,21,22)/b3-2+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance (2E)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}acrylic acid (2E)-3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}prop-2-enoic acid Not in list C13H9ClF3N3O3 O=C(O)/C=C/c1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F InChI=1/C13H9ClF3N3O3/c1-6-18-20(13(23)19(6)12(16)17)10-4-7(2-3-11(21)22)8(14)5-9(10)15/h2-5,12H,1H3,(H,21,22)/b3-2+ organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance (2E)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}acrylic acid (2E)-3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}prop-2-enoic acid Not in list C13H9ClF3N3O3 O=C(O)/C=C/c1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F InChI=1/C13H9ClF3N3O3/c1-6-18-20(13(23)19(6)12(16)17)10-4-7(2-3-11(21)22)8(14)5-9(10)15/h2-5,12H,1H3,(H,21,22)/b3-2+ organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance (2E)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}acrylic acid (2E)-3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}prop-2-enoic acid Not in list C13H9ClF3N3O3 O=C(O)/C=C/c1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F InChI=1/C13H9ClF3N3O3/c1-6-18-20(13(23)19(6)12(16)17)10-4-7(2-3-11(21)22)8(14)5-9(10)15/h2-5,12H,1H3,(H,21,22)/b3-2+ organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance (2E)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}acrylic acid (2E)-3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}prop-2-enoic acid Not in list C13H9ClF3N3O3 O=C(O)/C=C/c1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F InChI=1/C13H9ClF3N3O3/c1-6-18-20(13(23)19(6)12(16)17)10-4-7(2-3-11(21)22)8(14)5-9(10)15/h2-5,12H,1H3,(H,21,22)/b3-2+ organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance (2RS)-2-Chloro-3-{2-chloro-5-[4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid 2-chloro-3-{2-chloro-5-[4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid Not in list C12H8Cl2F3N3O3 O=C(O)C(Cl)Cc1cc(c(F)cc1Cl)N2N=CN(C2=O)C(F)F InChI=1/C12H8Cl2F3N3O3/c13-6-3-8(15)9(2-5(6)1-7(14)10(21)22)20-12(23)19(4-18-20)11(16)17/h2-4,7,11H,1H2,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance (2RS)-2-Chloro-3-{2-chloro-5-[4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid 2-chloro-3-{2-chloro-5-[4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid Not in list C12H8Cl2F3N3O3 O=C(O)C(Cl)Cc1cc(c(F)cc1Cl)N2N=CN(C2=O)C(F)F InChI=1/C12H8Cl2F3N3O3/c13-6-3-8(15)9(2-5(6)1-7(14)10(21)22)20-12(23)19(4-18-20)11(16)17/h2-4,7,11H,1H2,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance (2RS)-2-Chloro-3-{2-chloro-5-[4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid 2-chloro-3-{2-chloro-5-[4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid Not in list C12H8Cl2F3N3O3 O=C(O)C(Cl)Cc1cc(c(F)cc1Cl)N2N=CN(C2=O)C(F)F InChI=1/C12H8Cl2F3N3O3/c13-6-3-8(15)9(2-5(6)1-7(14)10(21)22)20-12(23)19(4-18-20)11(16)17/h2-4,7,11H,1H2,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance (2RS)-2-Chloro-3-{2-chloro-5-[4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid 2-chloro-3-{2-chloro-5-[4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid Not in list C12H8Cl2F3N3O3 O=C(O)C(Cl)Cc1cc(c(F)cc1Cl)N2N=CN(C2=O)C(F)F InChI=1/C12H8Cl2F3N3O3/c13-6-3-8(15)9(2-5(6)1-7(14)10(21)22)20-12(23)19(4-18-20)11(16)17/h2-4,7,11H,1H2,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance (2RS)-2-Chloro-3-{2-chloro-5-[4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid 2-chloro-3-{2-chloro-5-[4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid Not in list C12H8Cl2F3N3O3 O=C(O)C(Cl)Cc1cc(c(F)cc1Cl)N2N=CN(C2=O)C(F)F InChI=1/C12H8Cl2F3N3O3/c13-6-3-8(15)9(2-5(6)1-7(14)10(21)22)20-12(23)19(4-18-20)11(16)17/h2-4,7,11H,1H2,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance (2RS)-2-Chloro-3-{2-chloro-5-[4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid 2-chloro-3-{2-chloro-5-[4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid Not in list C12H8Cl2F3N3O3 O=C(O)C(Cl)Cc1cc(c(F)cc1Cl)N2N=CN(C2=O)C(F)F InChI=1/C12H8Cl2F3N3O3/c13-6-3-8(15)9(2-5(6)1-7(14)10(21)22)20-12(23)19(4-18-20)11(16)17/h2-4,7,11H,1H2,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance (2RS)-2-Chloro-3-{2-chloro-5-[4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid 2-chloro-3-{2-chloro-5-[4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid Not in list C12H8Cl2F3N3O3 O=C(O)C(Cl)Cc1cc(c(F)cc1Cl)N2N=CN(C2=O)C(F)F InChI=1/C12H8Cl2F3N3O3/c13-6-3-8(15)9(2-5(6)1-7(14)10(21)22)20-12(23)19(4-18-20)11(16)17/h2-4,7,11H,1H2,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance (2RS)-2-Chloro-3-{2-chloro-5-[4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid 2-chloro-3-{2-chloro-5-[4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid Not in list C12H8Cl2F3N3O3 O=C(O)C(Cl)Cc1cc(c(F)cc1Cl)N2N=CN(C2=O)C(F)F InChI=1/C12H8Cl2F3N3O3/c13-6-3-8(15)9(2-5(6)1-7(14)10(21)22)20-12(23)19(4-18-20)11(16)17/h2-4,7,11H,1H2,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance (2RS)-2-Chloro-3-{2-chloro-5-[4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid 2-chloro-3-{2-chloro-5-[4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid Not in list C12H8Cl2F3N3O3 O=C(O)C(Cl)Cc1cc(c(F)cc1Cl)N2N=CN(C2=O)C(F)F InChI=1/C12H8Cl2F3N3O3/c13-6-3-8(15)9(2-5(6)1-7(14)10(21)22)20-12(23)19(4-18-20)11(16)17/h2-4,7,11H,1H2,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance (2RS)-2-Chloro-3-{2-chloro-5-[4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid 2-chloro-3-{2-chloro-5-[4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid Not in list C12H8Cl2F3N3O3 O=C(O)C(Cl)Cc1cc(c(F)cc1Cl)N2N=CN(C2=O)C(F)F InChI=1/C12H8Cl2F3N3O3/c13-6-3-8(15)9(2-5(6)1-7(14)10(21)22)20-12(23)19(4-18-20)11(16)17/h2-4,7,11H,1H2,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance (2RS)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid 3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid Not in list C13H11ClF3N3O6S O=C(O)C(Cc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F)S(=O)(=O)O InChI=1/C13H11ClF3N3O6S/c1-5-18-20(13(23)19(5)12(16)17)9-2-6(7(14)4-8(9)15)3-10(11(21)22)27(24,25)26/h2,4,10,12H,3H2,1H3,(H,21,22)(H,24,25,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance (2RS)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid 3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid Not in list C13H11ClF3N3O6S O=C(O)C(Cc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F)S(=O)(=O)O InChI=1/C13H11ClF3N3O6S/c1-5-18-20(13(23)19(5)12(16)17)9-2-6(7(14)4-8(9)15)3-10(11(21)22)27(24,25)26/h2,4,10,12H,3H2,1H3,(H,21,22)(H,24,25,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance (2RS)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid 3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid Not in list C13H11ClF3N3O6S O=C(O)C(Cc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F)S(=O)(=O)O InChI=1/C13H11ClF3N3O6S/c1-5-18-20(13(23)19(5)12(16)17)9-2-6(7(14)4-8(9)15)3-10(11(21)22)27(24,25)26/h2,4,10,12H,3H2,1H3,(H,21,22)(H,24,25,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance (2RS)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid 3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid Not in list C13H11ClF3N3O6S O=C(O)C(Cc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F)S(=O)(=O)O InChI=1/C13H11ClF3N3O6S/c1-5-18-20(13(23)19(5)12(16)17)9-2-6(7(14)4-8(9)15)3-10(11(21)22)27(24,25)26/h2,4,10,12H,3H2,1H3,(H,21,22)(H,24,25,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance (2RS)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid 3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid Not in list C13H11ClF3N3O6S O=C(O)C(Cc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F)S(=O)(=O)O InChI=1/C13H11ClF3N3O6S/c1-5-18-20(13(23)19(5)12(16)17)9-2-6(7(14)4-8(9)15)3-10(11(21)22)27(24,25)26/h2,4,10,12H,3H2,1H3,(H,21,22)(H,24,25,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance (2RS)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid 3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid Not in list C13H11ClF3N3O6S O=C(O)C(Cc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F)S(=O)(=O)O InChI=1/C13H11ClF3N3O6S/c1-5-18-20(13(23)19(5)12(16)17)9-2-6(7(14)4-8(9)15)3-10(11(21)22)27(24,25)26/h2,4,10,12H,3H2,1H3,(H,21,22)(H,24,25,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance (2RS)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid 3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid Not in list C13H11ClF3N3O6S O=C(O)C(Cc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F)S(=O)(=O)O InChI=1/C13H11ClF3N3O6S/c1-5-18-20(13(23)19(5)12(16)17)9-2-6(7(14)4-8(9)15)3-10(11(21)22)27(24,25)26/h2,4,10,12H,3H2,1H3,(H,21,22)(H,24,25,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance (2RS)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid 3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid Not in list C13H11ClF3N3O6S O=C(O)C(Cc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F)S(=O)(=O)O InChI=1/C13H11ClF3N3O6S/c1-5-18-20(13(23)19(5)12(16)17)9-2-6(7(14)4-8(9)15)3-10(11(21)22)27(24,25)26/h2,4,10,12H,3H2,1H3,(H,21,22)(H,24,25,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance (2RS)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid 3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid Not in list C13H11ClF3N3O6S O=C(O)C(Cc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F)S(=O)(=O)O InChI=1/C13H11ClF3N3O6S/c1-5-18-20(13(23)19(5)12(16)17)9-2-6(7(14)4-8(9)15)3-10(11(21)22)27(24,25)26/h2,4,10,12H,3H2,1H3,(H,21,22)(H,24,25,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance (2RS)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid 3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid Not in list C13H11ClF3N3O6S O=C(O)C(Cc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F)S(=O)(=O)O InChI=1/C13H11ClF3N3O6S/c1-5-18-20(13(23)19(5)12(16)17)9-2-6(7(14)4-8(9)15)3-10(11(21)22)27(24,25)26/h2,4,10,12H,3H2,1H3,(H,21,22)(H,24,25,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance (2RS)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid 3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid Not in list C13H11ClF3N3O6S O=C(O)C(Cc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F)S(=O)(=O)O InChI=1/C13H11ClF3N3O6S/c1-5-18-20(13(23)19(5)12(16)17)9-2-6(7(14)4-8(9)15)3-10(11(21)22)27(24,25)26/h2,4,10,12H,3H2,1H3,(H,21,22)(H,24,25,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance (2RS)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid 3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid Not in list C13H11ClF3N3O6S O=C(O)C(Cc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F)S(=O)(=O)O InChI=1/C13H11ClF3N3O6S/c1-5-18-20(13(23)19(5)12(16)17)9-2-6(7(14)4-8(9)15)3-10(11(21)22)27(24,25)26/h2,4,10,12H,3H2,1H3,(H,21,22)(H,24,25,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance (2RS)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid 3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid Not in list C13H11ClF3N3O6S O=C(O)C(Cc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F)S(=O)(=O)O InChI=1/C13H11ClF3N3O6S/c1-5-18-20(13(23)19(5)12(16)17)9-2-6(7(14)4-8(9)15)3-10(11(21)22)27(24,25)26/h2,4,10,12H,3H2,1H3,(H,21,22)(H,24,25,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance (2RS)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid 3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid Not in list C13H11ClF3N3O6S O=C(O)C(Cc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F)S(=O)(=O)O InChI=1/C13H11ClF3N3O6S/c1-5-18-20(13(23)19(5)12(16)17)9-2-6(7(14)4-8(9)15)3-10(11(21)22)27(24,25)26/h2,4,10,12H,3H2,1H3,(H,21,22)(H,24,25,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance (2RS)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid 3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid Not in list C13H11ClF3N3O6S O=C(O)C(Cc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F)S(=O)(=O)O InChI=1/C13H11ClF3N3O6S/c1-5-18-20(13(23)19(5)12(16)17)9-2-6(7(14)4-8(9)15)3-10(11(21)22)27(24,25)26/h2,4,10,12H,3H2,1H3,(H,21,22)(H,24,25,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance (2RS)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid 3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid Not in list C13H11ClF3N3O6S O=C(O)C(Cc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F)S(=O)(=O)O InChI=1/C13H11ClF3N3O6S/c1-5-18-20(13(23)19(5)12(16)17)9-2-6(7(14)4-8(9)15)3-10(11(21)22)27(24,25)26/h2,4,10,12H,3H2,1H3,(H,21,22)(H,24,25,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance (2RS)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid 3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid Not in list C13H11ClF3N3O6S O=C(O)C(Cc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F)S(=O)(=O)O InChI=1/C13H11ClF3N3O6S/c1-5-18-20(13(23)19(5)12(16)17)9-2-6(7(14)4-8(9)15)3-10(11(21)22)27(24,25)26/h2,4,10,12H,3H2,1H3,(H,21,22)(H,24,25,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance (2RS)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid 3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid Not in list C13H11ClF3N3O6S O=C(O)C(Cc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F)S(=O)(=O)O InChI=1/C13H11ClF3N3O6S/c1-5-18-20(13(23)19(5)12(16)17)9-2-6(7(14)4-8(9)15)3-10(11(21)22)27(24,25)26/h2,4,10,12H,3H2,1H3,(H,21,22)(H,24,25,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance (2RS)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid 3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid Not in list C13H11ClF3N3O6S O=C(O)C(Cc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F)S(=O)(=O)O InChI=1/C13H11ClF3N3O6S/c1-5-18-20(13(23)19(5)12(16)17)9-2-6(7(14)4-8(9)15)3-10(11(21)22)27(24,25)26/h2,4,10,12H,3H2,1H3,(H,21,22)(H,24,25,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance (2RS)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid 3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid Not in list C13H11ClF3N3O6S O=C(O)C(Cc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F)S(=O)(=O)O InChI=1/C13H11ClF3N3O6S/c1-5-18-20(13(23)19(5)12(16)17)9-2-6(7(14)4-8(9)15)3-10(11(21)22)27(24,25)26/h2,4,10,12H,3H2,1H3,(H,21,22)(H,24,25,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance (2RS)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid 3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid Not in list C13H11ClF3N3O6S O=C(O)C(Cc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F)S(=O)(=O)O InChI=1/C13H11ClF3N3O6S/c1-5-18-20(13(23)19(5)12(16)17)9-2-6(7(14)4-8(9)15)3-10(11(21)22)27(24,25)26/h2,4,10,12H,3H2,1H3,(H,21,22)(H,24,25,26) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance (2RS)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid 3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid Not in list C13H11ClF3N3O6S O=C(O)C(Cc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F)S(=O)(=O)O InChI=1/C13H11ClF3N3O6S/c1-5-18-20(13(23)19(5)12(16)17)9-2-6(7(14)4-8(9)15)3-10(11(21)22)27(24,25)26/h2,4,10,12H,3H2,1H3,(H,21,22)(H,24,25,26) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance (2RS)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid 3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid Not in list C13H11ClF3N3O6S O=C(O)C(Cc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F)S(=O)(=O)O InChI=1/C13H11ClF3N3O6S/c1-5-18-20(13(23)19(5)12(16)17)9-2-6(7(14)4-8(9)15)3-10(11(21)22)27(24,25)26/h2,4,10,12H,3H2,1H3,(H,21,22)(H,24,25,26) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance (2RS)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid 3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid Not in list C13H11ClF3N3O6S O=C(O)C(Cc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F)S(=O)(=O)O InChI=1/C13H11ClF3N3O6S/c1-5-18-20(13(23)19(5)12(16)17)9-2-6(7(14)4-8(9)15)3-10(11(21)22)27(24,25)26/h2,4,10,12H,3H2,1H3,(H,21,22)(H,24,25,26) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 4-(Difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one 4-(difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one Not in list C4H5F2N3O O=C1NN=C(C)N1C(F)F InChI=1/C4H5F2N3O/c1-2-7-8-4(10)9(2)3(5)6/h3H,1H3,(H,8,10) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 4-(Difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one 4-(difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one Not in list C4H5F2N3O O=C1NN=C(C)N1C(F)F InChI=1/C4H5F2N3O/c1-2-7-8-4(10)9(2)3(5)6/h3H,1H3,(H,8,10) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 4-(Difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one 4-(difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one Not in list C4H5F2N3O O=C1NN=C(C)N1C(F)F InChI=1/C4H5F2N3O/c1-2-7-8-4(10)9(2)3(5)6/h3H,1H3,(H,8,10) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 4-(Difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one 4-(difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one Not in list C4H5F2N3O O=C1NN=C(C)N1C(F)F InChI=1/C4H5F2N3O/c1-2-7-8-4(10)9(2)3(5)6/h3H,1H3,(H,8,10) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 4-(Difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one 4-(difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one Not in list C4H5F2N3O O=C1NN=C(C)N1C(F)F InChI=1/C4H5F2N3O/c1-2-7-8-4(10)9(2)3(5)6/h3H,1H3,(H,8,10) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 4-(Difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one 4-(difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one Not in list C4H5F2N3O O=C1NN=C(C)N1C(F)F InChI=1/C4H5F2N3O/c1-2-7-8-4(10)9(2)3(5)6/h3H,1H3,(H,8,10) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 4-(Difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one 4-(difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one Not in list C4H5F2N3O O=C1NN=C(C)N1C(F)F InChI=1/C4H5F2N3O/c1-2-7-8-4(10)9(2)3(5)6/h3H,1H3,(H,8,10) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 4-(Difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one 4-(difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one Not in list C4H5F2N3O O=C1NN=C(C)N1C(F)F InChI=1/C4H5F2N3O/c1-2-7-8-4(10)9(2)3(5)6/h3H,1H3,(H,8,10) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 4-(Difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one 4-(difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one Not in list C4H5F2N3O O=C1NN=C(C)N1C(F)F InChI=1/C4H5F2N3O/c1-2-7-8-4(10)9(2)3(5)6/h3H,1H3,(H,8,10) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 4-(Difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one 4-(difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one Not in list C4H5F2N3O O=C1NN=C(C)N1C(F)F InChI=1/C4H5F2N3O/c1-2-7-8-4(10)9(2)3(5)6/h3H,1H3,(H,8,10) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 4-(Difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one 4-(difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one Not in list C4H5F2N3O O=C1NN=C(C)N1C(F)F InChI=1/C4H5F2N3O/c1-2-7-8-4(10)9(2)3(5)6/h3H,1H3,(H,8,10) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 4-(Difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one 4-(difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one Not in list C4H5F2N3O O=C1NN=C(C)N1C(F)F InChI=1/C4H5F2N3O/c1-2-7-8-4(10)9(2)3(5)6/h3H,1H3,(H,8,10) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 4-(Difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one 4-(difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one Not in list C4H5F2N3O O=C1NN=C(C)N1C(F)F InChI=1/C4H5F2N3O/c1-2-7-8-4(10)9(2)3(5)6/h3H,1H3,(H,8,10) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 4-(Difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one 4-(difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one Not in list C4H5F2N3O O=C1NN=C(C)N1C(F)F InChI=1/C4H5F2N3O/c1-2-7-8-4(10)9(2)3(5)6/h3H,1H3,(H,8,10) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 2-Chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid 380885-65-4 2-chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-1,2,4-triazol-1-yl]-4-fluorobenzoic acid Not in list C11H7ClF3N3O4 C1=C(C(=CC(=C1N2C(=O)N(C(=N2)CO)C(F)F)F)Cl)C(=O)O InChI=1S/C11H7ClF3N3O4/c12-5-2-6(13)7(1-4(5)9(20)21)18-11(22)17(10(14)15)8(3-19)16-18/h1-2,10,19H,3H2,(H,20,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 2-Chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid 380885-65-4 2-chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-1,2,4-triazol-1-yl]-4-fluorobenzoic acid Not in list C11H7ClF3N3O4 C1=C(C(=CC(=C1N2C(=O)N(C(=N2)CO)C(F)F)F)Cl)C(=O)O InChI=1S/C11H7ClF3N3O4/c12-5-2-6(13)7(1-4(5)9(20)21)18-11(22)17(10(14)15)8(3-19)16-18/h1-2,10,19H,3H2,(H,20,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 2-Chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid 380885-65-4 2-chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-1,2,4-triazol-1-yl]-4-fluorobenzoic acid Not in list C11H7ClF3N3O4 C1=C(C(=CC(=C1N2C(=O)N(C(=N2)CO)C(F)F)F)Cl)C(=O)O InChI=1S/C11H7ClF3N3O4/c12-5-2-6(13)7(1-4(5)9(20)21)18-11(22)17(10(14)15)8(3-19)16-18/h1-2,10,19H,3H2,(H,20,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 2-Chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid 380885-65-4 2-chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-1,2,4-triazol-1-yl]-4-fluorobenzoic acid Not in list C11H7ClF3N3O4 C1=C(C(=CC(=C1N2C(=O)N(C(=N2)CO)C(F)F)F)Cl)C(=O)O InChI=1S/C11H7ClF3N3O4/c12-5-2-6(13)7(1-4(5)9(20)21)18-11(22)17(10(14)15)8(3-19)16-18/h1-2,10,19H,3H2,(H,20,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 2-Chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid 380885-65-4 2-chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-1,2,4-triazol-1-yl]-4-fluorobenzoic acid Not in list C11H7ClF3N3O4 C1=C(C(=CC(=C1N2C(=O)N(C(=N2)CO)C(F)F)F)Cl)C(=O)O InChI=1S/C11H7ClF3N3O4/c12-5-2-6(13)7(1-4(5)9(20)21)18-11(22)17(10(14)15)8(3-19)16-18/h1-2,10,19H,3H2,(H,20,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 2-Chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid 380885-65-4 2-chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-1,2,4-triazol-1-yl]-4-fluorobenzoic acid Not in list C11H7ClF3N3O4 C1=C(C(=CC(=C1N2C(=O)N(C(=N2)CO)C(F)F)F)Cl)C(=O)O InChI=1S/C11H7ClF3N3O4/c12-5-2-6(13)7(1-4(5)9(20)21)18-11(22)17(10(14)15)8(3-19)16-18/h1-2,10,19H,3H2,(H,20,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 2-Chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid 380885-65-4 2-chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-1,2,4-triazol-1-yl]-4-fluorobenzoic acid Not in list C11H7ClF3N3O4 C1=C(C(=CC(=C1N2C(=O)N(C(=N2)CO)C(F)F)F)Cl)C(=O)O InChI=1S/C11H7ClF3N3O4/c12-5-2-6(13)7(1-4(5)9(20)21)18-11(22)17(10(14)15)8(3-19)16-18/h1-2,10,19H,3H2,(H,20,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 2-Chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid 380885-65-4 2-chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-1,2,4-triazol-1-yl]-4-fluorobenzoic acid Not in list C11H7ClF3N3O4 C1=C(C(=CC(=C1N2C(=O)N(C(=N2)CO)C(F)F)F)Cl)C(=O)O InChI=1S/C11H7ClF3N3O4/c12-5-2-6(13)7(1-4(5)9(20)21)18-11(22)17(10(14)15)8(3-19)16-18/h1-2,10,19H,3H2,(H,20,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 2-Chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid 380885-65-4 2-chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-1,2,4-triazol-1-yl]-4-fluorobenzoic acid Not in list C11H7ClF3N3O4 C1=C(C(=CC(=C1N2C(=O)N(C(=N2)CO)C(F)F)F)Cl)C(=O)O InChI=1S/C11H7ClF3N3O4/c12-5-2-6(13)7(1-4(5)9(20)21)18-11(22)17(10(14)15)8(3-19)16-18/h1-2,10,19H,3H2,(H,20,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 2-Chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid 380885-65-4 2-chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-1,2,4-triazol-1-yl]-4-fluorobenzoic acid Not in list C11H7ClF3N3O4 C1=C(C(=CC(=C1N2C(=O)N(C(=N2)CO)C(F)F)F)Cl)C(=O)O InChI=1S/C11H7ClF3N3O4/c12-5-2-6(13)7(1-4(5)9(20)21)18-11(22)17(10(14)15)8(3-19)16-18/h1-2,10,19H,3H2,(H,20,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 4-(Difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one 4-(difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one Not in list C4H5F2N3O O=C1NN=C(C)N1C(F)F InChI=1/C4H5F2N3O/c1-2-7-8-4(10)9(2)3(5)6/h3H,1H3,(H,8,10) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 4-(Difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one 4-(difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one Not in list C4H5F2N3O O=C1NN=C(C)N1C(F)F InChI=1/C4H5F2N3O/c1-2-7-8-4(10)9(2)3(5)6/h3H,1H3,(H,8,10) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 2-Chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid 380885-65-4 2-chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-1,2,4-triazol-1-yl]-4-fluorobenzoic acid Not in list C11H7ClF3N3O4 C1=C(C(=CC(=C1N2C(=O)N(C(=N2)CO)C(F)F)F)Cl)C(=O)O InChI=1S/C11H7ClF3N3O4/c12-5-2-6(13)7(1-4(5)9(20)21)18-11(22)17(10(14)15)8(3-19)16-18/h1-2,10,19H,3H2,(H,20,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 2-Chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid 380885-65-4 2-chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-1,2,4-triazol-1-yl]-4-fluorobenzoic acid Not in list C11H7ClF3N3O4 C1=C(C(=CC(=C1N2C(=O)N(C(=N2)CO)C(F)F)F)Cl)C(=O)O InChI=1S/C11H7ClF3N3O4/c12-5-2-6(13)7(1-4(5)9(20)21)18-11(22)17(10(14)15)8(3-19)16-18/h1-2,10,19H,3H2,(H,20,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 2-Chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid 380885-65-4 2-chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-1,2,4-triazol-1-yl]-4-fluorobenzoic acid Not in list C11H7ClF3N3O4 C1=C(C(=CC(=C1N2C(=O)N(C(=N2)CO)C(F)F)F)Cl)C(=O)O InChI=1S/C11H7ClF3N3O4/c12-5-2-6(13)7(1-4(5)9(20)21)18-11(22)17(10(14)15)8(3-19)16-18/h1-2,10,19H,3H2,(H,20,21) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable Rat (as animal) Not reported 10 Male/Female Not reported 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 2-Chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid 380885-65-4 2-chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-1,2,4-triazol-1-yl]-4-fluorobenzoic acid Not in list C11H7ClF3N3O4 C1=C(C(=CC(=C1N2C(=O)N(C(=N2)CO)C(F)F)F)Cl)C(=O)O InChI=1S/C11H7ClF3N3O4/c12-5-2-6(13)7(1-4(5)9(20)21)18-11(22)17(10(14)15)8(3-19)16-18/h1-2,10,19H,3H2,(H,20,21) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable Rat (as animal) Not reported 10 Male/Female Not reported 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 2-(4-Chloro-2-fluoro-5-methoxyphenyl)-4-(difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one 97986-18-0 2-(4-chloro-2-fluoro-5-methoxyphenyl)-4-(difluoromethyl)-5-methyl-1,2,4-triazol-3-one Not in list C11H9ClF3N3O2 CC1=NN(C(=O)N1C(F)F)C2=CC(=C(C=C2F)Cl)OC InChI=1S/C11H9ClF3N3O2/c1-5-16-18(11(19)17(5)10(14)15)8-4-9(20-2)6(12)3-7(8)13/h3-4,10H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 2-(4-Chloro-2-fluoro-5-methoxyphenyl)-4-(difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one 97986-18-0 2-(4-chloro-2-fluoro-5-methoxyphenyl)-4-(difluoromethyl)-5-methyl-1,2,4-triazol-3-one Not in list C11H9ClF3N3O2 CC1=NN(C(=O)N1C(F)F)C2=CC(=C(C=C2F)Cl)OC InChI=1S/C11H9ClF3N3O2/c1-5-16-18(11(19)17(5)10(14)15)8-4-9(20-2)6(12)3-7(8)13/h3-4,10H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 2-(4-Chloro-2-fluoro-5-methoxyphenyl)-4-(difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one 97986-18-0 2-(4-chloro-2-fluoro-5-methoxyphenyl)-4-(difluoromethyl)-5-methyl-1,2,4-triazol-3-one Not in list C11H9ClF3N3O2 CC1=NN(C(=O)N1C(F)F)C2=CC(=C(C=C2F)Cl)OC InChI=1S/C11H9ClF3N3O2/c1-5-16-18(11(19)17(5)10(14)15)8-4-9(20-2)6(12)3-7(8)13/h3-4,10H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 2-(4-Chloro-2-fluoro-5-methoxyphenyl)-4-(difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one 97986-18-0 2-(4-chloro-2-fluoro-5-methoxyphenyl)-4-(difluoromethyl)-5-methyl-1,2,4-triazol-3-one Not in list C11H9ClF3N3O2 CC1=NN(C(=O)N1C(F)F)C2=CC(=C(C=C2F)Cl)OC InChI=1S/C11H9ClF3N3O2/c1-5-16-18(11(19)17(5)10(14)15)8-4-9(20-2)6(12)3-7(8)13/h3-4,10H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 2-(4-Chloro-2-fluoro-5-methoxyphenyl)-4-(difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one 97986-18-0 2-(4-chloro-2-fluoro-5-methoxyphenyl)-4-(difluoromethyl)-5-methyl-1,2,4-triazol-3-one Not in list C11H9ClF3N3O2 CC1=NN(C(=O)N1C(F)F)C2=CC(=C(C=C2F)Cl)OC InChI=1S/C11H9ClF3N3O2/c1-5-16-18(11(19)17(5)10(14)15)8-4-9(20-2)6(12)3-7(8)13/h3-4,10H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 2-(4-Chloro-2-fluoro-5-methoxyphenyl)-4-(difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one 97986-18-0 2-(4-chloro-2-fluoro-5-methoxyphenyl)-4-(difluoromethyl)-5-methyl-1,2,4-triazol-3-one Not in list C11H9ClF3N3O2 CC1=NN(C(=O)N1C(F)F)C2=CC(=C(C=C2F)Cl)OC InChI=1S/C11H9ClF3N3O2/c1-5-16-18(11(19)17(5)10(14)15)8-4-9(20-2)6(12)3-7(8)13/h3-4,10H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 2-(4-Chloro-2-fluoro-5-methoxyphenyl)-4-(difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one 97986-18-0 2-(4-chloro-2-fluoro-5-methoxyphenyl)-4-(difluoromethyl)-5-methyl-1,2,4-triazol-3-one Not in list C11H9ClF3N3O2 CC1=NN(C(=O)N1C(F)F)C2=CC(=C(C=C2F)Cl)OC InChI=1S/C11H9ClF3N3O2/c1-5-16-18(11(19)17(5)10(14)15)8-4-9(20-2)6(12)3-7(8)13/h3-4,10H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 2-(4-Chloro-2-fluoro-5-methoxyphenyl)-4-(difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one 97986-18-0 2-(4-chloro-2-fluoro-5-methoxyphenyl)-4-(difluoromethyl)-5-methyl-1,2,4-triazol-3-one Not in list C11H9ClF3N3O2 CC1=NN(C(=O)N1C(F)F)C2=CC(=C(C=C2F)Cl)OC InChI=1S/C11H9ClF3N3O2/c1-5-16-18(11(19)17(5)10(14)15)8-4-9(20-2)6(12)3-7(8)13/h3-4,10H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 2-(4-Chloro-2-fluoro-5-methoxyphenyl)-4-(difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one 97986-18-0 2-(4-chloro-2-fluoro-5-methoxyphenyl)-4-(difluoromethyl)-5-methyl-1,2,4-triazol-3-one Not in list C11H9ClF3N3O2 CC1=NN(C(=O)N1C(F)F)C2=CC(=C(C=C2F)Cl)OC InChI=1S/C11H9ClF3N3O2/c1-5-16-18(11(19)17(5)10(14)15)8-4-9(20-2)6(12)3-7(8)13/h3-4,10H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 2-(4-Chloro-2-fluoro-5-methoxyphenyl)-4-(difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one 97986-18-0 2-(4-chloro-2-fluoro-5-methoxyphenyl)-4-(difluoromethyl)-5-methyl-1,2,4-triazol-3-one Not in list C11H9ClF3N3O2 CC1=NN(C(=O)N1C(F)F)C2=CC(=C(C=C2F)Cl)OC InChI=1S/C11H9ClF3N3O2/c1-5-16-18(11(19)17(5)10(14)15)8-4-9(20-2)6(12)3-7(8)13/h3-4,10H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 2-(4-Chloro-2-fluoro-5-methoxyphenyl)-4-(difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one 97986-18-0 2-(4-chloro-2-fluoro-5-methoxyphenyl)-4-(difluoromethyl)-5-methyl-1,2,4-triazol-3-one Not in list C11H9ClF3N3O2 CC1=NN(C(=O)N1C(F)F)C2=CC(=C(C=C2F)Cl)OC InChI=1S/C11H9ClF3N3O2/c1-5-16-18(11(19)17(5)10(14)15)8-4-9(20-2)6(12)3-7(8)13/h3-4,10H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 2-(4-Chloro-2-fluoro-5-methoxyphenyl)-4-(difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one 97986-18-0 2-(4-chloro-2-fluoro-5-methoxyphenyl)-4-(difluoromethyl)-5-methyl-1,2,4-triazol-3-one Not in list C11H9ClF3N3O2 CC1=NN(C(=O)N1C(F)F)C2=CC(=C(C=C2F)Cl)OC InChI=1S/C11H9ClF3N3O2/c1-5-16-18(11(19)17(5)10(14)15)8-4-9(20-2)6(12)3-7(8)13/h3-4,10H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 2-(4-Chloro-2-fluoro-5-methoxyphenyl)-4-(difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one 97986-18-0 2-(4-chloro-2-fluoro-5-methoxyphenyl)-4-(difluoromethyl)-5-methyl-1,2,4-triazol-3-one Not in list C11H9ClF3N3O2 CC1=NN(C(=O)N1C(F)F)C2=CC(=C(C=C2F)Cl)OC InChI=1S/C11H9ClF3N3O2/c1-5-16-18(11(19)17(5)10(14)15)8-4-9(20-2)6(12)3-7(8)13/h3-4,10H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 2-(4-Chloro-2-fluoro-5-methoxyphenyl)-4-(difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one 97986-18-0 2-(4-chloro-2-fluoro-5-methoxyphenyl)-4-(difluoromethyl)-5-methyl-1,2,4-triazol-3-one Not in list C11H9ClF3N3O2 CC1=NN(C(=O)N1C(F)F)C2=CC(=C(C=C2F)Cl)OC InChI=1S/C11H9ClF3N3O2/c1-5-16-18(11(19)17(5)10(14)15)8-4-9(20-2)6(12)3-7(8)13/h3-4,10H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 1-(5-Carboxy-4-chloro-2-fluorophenyl)-4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid 1-(5-carboxy-4-chloro-2-fluorophenyl)-4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid Not in list C11H5ClF3N3O5 O=C(O)c1cc(c(F)cc1Cl)N2N=C(N(C2=O)C(F)F)C(=O)O InChI=1/C11H5ClF3N3O5/c12-4-2-5(13)6(1-3(4)8(19)20)18-11(23)17(10(14)15)7(16-18)9(21)22/h1-2,10H,(H,19,20)(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 1-(5-Carboxy-4-chloro-2-fluorophenyl)-4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid 1-(5-carboxy-4-chloro-2-fluorophenyl)-4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid Not in list C11H5ClF3N3O5 O=C(O)c1cc(c(F)cc1Cl)N2N=C(N(C2=O)C(F)F)C(=O)O InChI=1/C11H5ClF3N3O5/c12-4-2-5(13)6(1-3(4)8(19)20)18-11(23)17(10(14)15)7(16-18)9(21)22/h1-2,10H,(H,19,20)(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 1-(5-Carboxy-4-chloro-2-fluorophenyl)-4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid 1-(5-carboxy-4-chloro-2-fluorophenyl)-4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid Not in list C11H5ClF3N3O5 O=C(O)c1cc(c(F)cc1Cl)N2N=C(N(C2=O)C(F)F)C(=O)O InChI=1/C11H5ClF3N3O5/c12-4-2-5(13)6(1-3(4)8(19)20)18-11(23)17(10(14)15)7(16-18)9(21)22/h1-2,10H,(H,19,20)(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 1-(5-Carboxy-4-chloro-2-fluorophenyl)-4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid 1-(5-carboxy-4-chloro-2-fluorophenyl)-4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid Not in list C11H5ClF3N3O5 O=C(O)c1cc(c(F)cc1Cl)N2N=C(N(C2=O)C(F)F)C(=O)O InChI=1/C11H5ClF3N3O5/c12-4-2-5(13)6(1-3(4)8(19)20)18-11(23)17(10(14)15)7(16-18)9(21)22/h1-2,10H,(H,19,20)(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 1-(5-Carboxy-4-chloro-2-fluorophenyl)-4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid 1-(5-carboxy-4-chloro-2-fluorophenyl)-4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid Not in list C11H5ClF3N3O5 O=C(O)c1cc(c(F)cc1Cl)N2N=C(N(C2=O)C(F)F)C(=O)O InChI=1/C11H5ClF3N3O5/c12-4-2-5(13)6(1-3(4)8(19)20)18-11(23)17(10(14)15)7(16-18)9(21)22/h1-2,10H,(H,19,20)(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 1-(5-Carboxy-4-chloro-2-fluorophenyl)-4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid 1-(5-carboxy-4-chloro-2-fluorophenyl)-4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid Not in list C11H5ClF3N3O5 O=C(O)c1cc(c(F)cc1Cl)N2N=C(N(C2=O)C(F)F)C(=O)O InChI=1/C11H5ClF3N3O5/c12-4-2-5(13)6(1-3(4)8(19)20)18-11(23)17(10(14)15)7(16-18)9(21)22/h1-2,10H,(H,19,20)(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 1-(5-Carboxy-4-chloro-2-fluorophenyl)-4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid 1-(5-carboxy-4-chloro-2-fluorophenyl)-4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid Not in list C11H5ClF3N3O5 O=C(O)c1cc(c(F)cc1Cl)N2N=C(N(C2=O)C(F)F)C(=O)O InChI=1/C11H5ClF3N3O5/c12-4-2-5(13)6(1-3(4)8(19)20)18-11(23)17(10(14)15)7(16-18)9(21)22/h1-2,10H,(H,19,20)(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 1-(5-Carboxy-4-chloro-2-fluorophenyl)-4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid 1-(5-carboxy-4-chloro-2-fluorophenyl)-4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid Not in list C11H5ClF3N3O5 O=C(O)c1cc(c(F)cc1Cl)N2N=C(N(C2=O)C(F)F)C(=O)O InChI=1/C11H5ClF3N3O5/c12-4-2-5(13)6(1-3(4)8(19)20)18-11(23)17(10(14)15)7(16-18)9(21)22/h1-2,10H,(H,19,20)(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 1-(5-Carboxy-4-chloro-2-fluorophenyl)-4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid 1-(5-carboxy-4-chloro-2-fluorophenyl)-4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid Not in list C11H5ClF3N3O5 O=C(O)c1cc(c(F)cc1Cl)N2N=C(N(C2=O)C(F)F)C(=O)O InChI=1/C11H5ClF3N3O5/c12-4-2-5(13)6(1-3(4)8(19)20)18-11(23)17(10(14)15)7(16-18)9(21)22/h1-2,10H,(H,19,20)(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 1-(5-Carboxy-4-chloro-2-fluorophenyl)-4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid 1-(5-carboxy-4-chloro-2-fluorophenyl)-4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid Not in list C11H5ClF3N3O5 O=C(O)c1cc(c(F)cc1Cl)N2N=C(N(C2=O)C(F)F)C(=O)O InChI=1/C11H5ClF3N3O5/c12-4-2-5(13)6(1-3(4)8(19)20)18-11(23)17(10(14)15)7(16-18)9(21)22/h1-2,10H,(H,19,20)(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 1-(5-Carboxy-4-chloro-2-fluorophenyl)-4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid 1-(5-carboxy-4-chloro-2-fluorophenyl)-4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid Not in list C11H5ClF3N3O5 O=C(O)c1cc(c(F)cc1Cl)N2N=C(N(C2=O)C(F)F)C(=O)O InChI=1/C11H5ClF3N3O5/c12-4-2-5(13)6(1-3(4)8(19)20)18-11(23)17(10(14)15)7(16-18)9(21)22/h1-2,10H,(H,19,20)(H,21,22) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Positive RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 1-(5-Carboxy-4-chloro-2-fluorophenyl)-4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid 1-(5-carboxy-4-chloro-2-fluorophenyl)-4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid Not in list C11H5ClF3N3O5 O=C(O)c1cc(c(F)cc1Cl)N2N=C(N(C2=O)C(F)F)C(=O)O InChI=1/C11H5ClF3N3O5/c12-4-2-5(13)6(1-3(4)8(19)20)18-11(23)17(10(14)15)7(16-18)9(21)22/h1-2,10H,(H,19,20)(H,21,22) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Positive RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 1-(5-Carboxy-4-chloro-2-fluorophenyl)-4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid 1-(5-carboxy-4-chloro-2-fluorophenyl)-4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid Not in list C11H5ClF3N3O5 O=C(O)c1cc(c(F)cc1Cl)N2N=C(N(C2=O)C(F)F)C(=O)O InChI=1/C11H5ClF3N3O5/c12-4-2-5(13)6(1-3(4)8(19)20)18-11(23)17(10(14)15)7(16-18)9(21)22/h1-2,10H,(H,19,20)(H,21,22) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 1-(5-Carboxy-4-chloro-2-fluorophenyl)-4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid 1-(5-carboxy-4-chloro-2-fluorophenyl)-4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid Not in list C11H5ClF3N3O5 O=C(O)c1cc(c(F)cc1Cl)N2N=C(N(C2=O)C(F)F)C(=O)O InChI=1/C11H5ClF3N3O5/c12-4-2-5(13)6(1-3(4)8(19)20)18-11(23)17(10(14)15)7(16-18)9(21)22/h1-2,10H,(H,19,20)(H,21,22) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 1-(5-Carboxy-4-chloro-2-fluorophenyl)-4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid 1-(5-carboxy-4-chloro-2-fluorophenyl)-4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid Not in list C11H5ClF3N3O5 O=C(O)c1cc(c(F)cc1Cl)N2N=C(N(C2=O)C(F)F)C(=O)O InChI=1/C11H5ClF3N3O5/c12-4-2-5(13)6(1-3(4)8(19)20)18-11(23)17(10(14)15)7(16-18)9(21)22/h1-2,10H,(H,19,20)(H,21,22) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable Rat (as animal) Sprague-Dawley 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 1-(5-Carboxy-4-chloro-2-fluorophenyl)-4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid 1-(5-carboxy-4-chloro-2-fluorophenyl)-4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid Not in list C11H5ClF3N3O5 O=C(O)c1cc(c(F)cc1Cl)N2N=C(N(C2=O)C(F)F)C(=O)O InChI=1/C11H5ClF3N3O5/c12-4-2-5(13)6(1-3(4)8(19)20)18-11(23)17(10(14)15)7(16-18)9(21)22/h1-2,10H,(H,19,20)(H,21,22) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable Rat (as animal) Sprague-Dawley 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance Carfentrazone ethyl lysimeter percolate Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance Carfentrazone ethyl lysimeter percolate Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance Carfentrazone ethyl lysimeter percolate Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance Carfentrazone ethyl lysimeter percolate Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance Carfentrazone ethyl lysimeter percolate Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance Carfentrazone ethyl lysimeter percolate Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance Carfentrazone ethyl lysimeter percolate Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance Carfentrazone ethyl lysimeter percolate Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance Carfentrazone ethyl lysimeter percolate Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance Carfentrazone ethyl lysimeter percolate Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Diuron 206-354-4 330-54-1 single chemical entity Component is identical to the substance Diuron 206-354-4 330-54-1 3-(3,4-dichlorophenyl)-1,1-dimethylurea Diuron C9H10Cl2N2O CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is identical to the substance Diuron 206-354-4 330-54-1 3-(3,4-dichlorophenyl)-1,1-dimethylurea Diuron C9H10Cl2N2O CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle without Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is identical to the substance Diuron 206-354-4 330-54-1 3-(3,4-dichlorophenyl)-1,1-dimethylurea Diuron C9H10Cl2N2O CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is identical to the substance Diuron 206-354-4 330-54-1 3-(3,4-dichlorophenyl)-1,1-dimethylurea Diuron C9H10Cl2N2O CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is identical to the substance Diuron 206-354-4 330-54-1 3-(3,4-dichlorophenyl)-1,1-dimethylurea Diuron C9H10Cl2N2O CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is identical to the substance Diuron 206-354-4 330-54-1 3-(3,4-dichlorophenyl)-1,1-dimethylurea Diuron C9H10Cl2N2O CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is identical to the substance Diuron 206-354-4 330-54-1 3-(3,4-dichlorophenyl)-1,1-dimethylurea Diuron C9H10Cl2N2O CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle with Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is identical to the substance Diuron 206-354-4 330-54-1 3-(3,4-dichlorophenyl)-1,1-dimethylurea Diuron C9H10Cl2N2O CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is identical to the substance Diuron 206-354-4 330-54-1 3-(3,4-dichlorophenyl)-1,1-dimethylurea Diuron C9H10Cl2N2O CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is identical to the substance Diuron 206-354-4 330-54-1 3-(3,4-dichlorophenyl)-1,1-dimethylurea Diuron C9H10Cl2N2O CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is identical to the substance Diuron 206-354-4 330-54-1 3-(3,4-dichlorophenyl)-1,1-dimethylurea Diuron C9H10Cl2N2O CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is identical to the substance Diuron 206-354-4 330-54-1 3-(3,4-dichlorophenyl)-1,1-dimethylurea Diuron C9H10Cl2N2O CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is identical to the substance Diuron 206-354-4 330-54-1 3-(3,4-dichlorophenyl)-1,1-dimethylurea Diuron C9H10Cl2N2O CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is identical to the substance Diuron 206-354-4 330-54-1 3-(3,4-dichlorophenyl)-1,1-dimethylurea Diuron C9H10Cl2N2O CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is identical to the substance Diuron 206-354-4 330-54-1 3-(3,4-dichlorophenyl)-1,1-dimethylurea Diuron C9H10Cl2N2O CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is identical to the substance Diuron 206-354-4 330-54-1 3-(3,4-dichlorophenyl)-1,1-dimethylurea Diuron C9H10Cl2N2O CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is identical to the substance Diuron 206-354-4 330-54-1 3-(3,4-dichlorophenyl)-1,1-dimethylurea Diuron C9H10Cl2N2O CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is identical to the substance Diuron 206-354-4 330-54-1 3-(3,4-dichlorophenyl)-1,1-dimethylurea Diuron C9H10Cl2N2O CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is identical to the substance Diuron 206-354-4 330-54-1 3-(3,4-dichlorophenyl)-1,1-dimethylurea Diuron C9H10Cl2N2O CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is identical to the substance Diuron 206-354-4 330-54-1 3-(3,4-dichlorophenyl)-1,1-dimethylurea Diuron C9H10Cl2N2O CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is identical to the substance Diuron 206-354-4 330-54-1 3-(3,4-dichlorophenyl)-1,1-dimethylurea Diuron C9H10Cl2N2O CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is identical to the substance Diuron 206-354-4 330-54-1 3-(3,4-dichlorophenyl)-1,1-dimethylurea Diuron C9H10Cl2N2O CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is identical to the substance Diuron 206-354-4 330-54-1 3-(3,4-dichlorophenyl)-1,1-dimethylurea Diuron C9H10Cl2N2O CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is identical to the substance Diuron 206-354-4 330-54-1 3-(3,4-dichlorophenyl)-1,1-dimethylurea Diuron C9H10Cl2N2O CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is identical to the substance Diuron 206-354-4 330-54-1 3-(3,4-dichlorophenyl)-1,1-dimethylurea Diuron C9H10Cl2N2O CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is identical to the substance Diuron 206-354-4 330-54-1 3-(3,4-dichlorophenyl)-1,1-dimethylurea Diuron C9H10Cl2N2O CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is identical to the substance Diuron 206-354-4 330-54-1 3-(3,4-dichlorophenyl)-1,1-dimethylurea Diuron C9H10Cl2N2O CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is identical to the substance Diuron 206-354-4 330-54-1 3-(3,4-dichlorophenyl)-1,1-dimethylurea Diuron C9H10Cl2N2O CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is identical to the substance Diuron 206-354-4 330-54-1 3-(3,4-dichlorophenyl)-1,1-dimethylurea Diuron C9H10Cl2N2O CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is identical to the substance Diuron 206-354-4 330-54-1 3-(3,4-dichlorophenyl)-1,1-dimethylurea Diuron C9H10Cl2N2O CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is identical to the substance Diuron 206-354-4 330-54-1 3-(3,4-dichlorophenyl)-1,1-dimethylurea Diuron C9H10Cl2N2O CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is identical to the substance Diuron 206-354-4 330-54-1 3-(3,4-dichlorophenyl)-1,1-dimethylurea Diuron C9H10Cl2N2O CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is identical to the substance Diuron 206-354-4 330-54-1 3-(3,4-dichlorophenyl)-1,1-dimethylurea Diuron C9H10Cl2N2O CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Positive RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is identical to the substance Diuron 206-354-4 330-54-1 3-(3,4-dichlorophenyl)-1,1-dimethylurea Diuron C9H10Cl2N2O CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Positive RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is identical to the substance Diuron 206-354-4 330-54-1 3-(3,4-dichlorophenyl)-1,1-dimethylurea Diuron C9H10Cl2N2O CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) W3110 Not reported yes, concurrent vehicle without Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is identical to the substance Diuron 206-354-4 330-54-1 3-(3,4-dichlorophenyl)-1,1-dimethylurea Diuron C9H10Cl2N2O CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) W3110 Not reported yes, concurrent vehicle with Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is identical to the substance Diuron 206-354-4 330-54-1 3-(3,4-dichlorophenyl)-1,1-dimethylurea Diuron C9H10Cl2N2O CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) (k12)p3478 Not reported yes, concurrent vehicle without Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is identical to the substance Diuron 206-354-4 330-54-1 3-(3,4-dichlorophenyl)-1,1-dimethylurea Diuron C9H10Cl2N2O CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) (k12)p3478 Not reported yes, concurrent vehicle with Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is identical to the substance Diuron 206-354-4 330-54-1 3-(3,4-dichlorophenyl)-1,1-dimethylurea Diuron C9H10Cl2N2O CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is identical to the substance Diuron 206-354-4 330-54-1 3-(3,4-dichlorophenyl)-1,1-dimethylurea Diuron C9H10Cl2N2O CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Rat (as animal) Sprague-Dawley 30 Male/Female oral: gavage 6.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is identical to the substance Diuron 206-354-4 330-54-1 3-(3,4-dichlorophenyl)-1,1-dimethylurea Diuron C9H10Cl2N2O CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Rat (as animal) Sprague-Dawley 30 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is identical to the substance Diuron 206-354-4 330-54-1 3-(3,4-dichlorophenyl)-1,1-dimethylurea Diuron C9H10Cl2N2O CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Rat (as animal) Sprague-Dawley 30 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is identical to the substance Diuron 206-354-4 330-54-1 3-(3,4-dichlorophenyl)-1,1-dimethylurea Diuron C9H10Cl2N2O CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Hamster (as animal) Chinese 20 Male/Female Not reported 48.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is identical to the substance Diuron 206-354-4 330-54-1 3-(3,4-dichlorophenyl)-1,1-dimethylurea Diuron C9H10Cl2N2O CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Hamster (as animal) Chinese 20 Male/Female Not reported 6.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is identical to the substance Diuron 206-354-4 330-54-1 3-(3,4-dichlorophenyl)-1,1-dimethylurea Diuron C9H10Cl2N2O CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Hamster (as animal) Chinese 20 Male/Female Not reported 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is identical to the substance Diuron 206-354-4 330-54-1 3-(3,4-dichlorophenyl)-1,1-dimethylurea Diuron C9H10Cl2N2O CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female oral: unspecified 24.0000000000 h yes not applicable Negative no evidence RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is identical to the substance Diuron 206-354-4 330-54-1 3-(3,4-dichlorophenyl)-1,1-dimethylurea Diuron C9H10Cl2N2O CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female oral: unspecified 72.0000000000 h yes not applicable Negative no evidence RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is identical to the substance Diuron 206-354-4 330-54-1 3-(3,4-dichlorophenyl)-1,1-dimethylurea Diuron C9H10Cl2N2O CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female oral: unspecified 48.0000000000 h yes not applicable Negative no evidence RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is identical to the substance Diuron 206-354-4 330-54-1 3-(3,4-dichlorophenyl)-1,1-dimethylurea Diuron C9H10Cl2N2O CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female intraperitoneal 48.0000000000 h yes not applicable Negative no evidence RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is identical to the substance Diuron 206-354-4 330-54-1 3-(3,4-dichlorophenyl)-1,1-dimethylurea Diuron C9H10Cl2N2O CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female intraperitoneal 16.0000000000 h yes not applicable Negative no evidence RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is identical to the substance Diuron 206-354-4 330-54-1 3-(3,4-dichlorophenyl)-1,1-dimethylurea Diuron C9H10Cl2N2O CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female intraperitoneal 24.0000000000 h yes not applicable Negative no evidence RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is identical to the substance Diuron 206-354-4 330-54-1 3-(3,4-dichlorophenyl)-1,1-dimethylurea Diuron C9H10Cl2N2O CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Swiss 12 Male/Female intraperitoneal 72.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is identical to the substance Diuron 206-354-4 330-54-1 3-(3,4-dichlorophenyl)-1,1-dimethylurea Diuron C9H10Cl2N2O CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Swiss 12 Male/Female intraperitoneal 48.0000000000 h yes, concurrent vehicle not applicable Positive no evidence RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is identical to the substance Diuron 206-354-4 330-54-1 3-(3,4-dichlorophenyl)-1,1-dimethylurea Diuron C9H10Cl2N2O CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Swiss 12 Male/Female intraperitoneal 30.0000000000 h yes, concurrent vehicle not applicable Positive no evidence RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is identical to the substance Diuron 206-354-4 330-54-1 3-(3,4-dichlorophenyl)-1,1-dimethylurea Diuron C9H10Cl2N2O CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vivo No guideline available Not reported Not applicable Acceptable Hamster (as animal) Chinese 12 Male/Female oral: unspecified 24.0000000000 h yes not applicable Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is identical to the substance Diuron 206-354-4 330-54-1 3-(3,4-dichlorophenyl)-1,1-dimethylurea Diuron C9H10Cl2N2O CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Not reported 6 Female oral: feed 7.0000000000 D yes not applicable Ambiguous RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is identical to the substance Diuron 206-354-4 330-54-1 3-(3,4-dichlorophenyl)-1,1-dimethylurea Diuron C9H10Cl2N2O CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration mammalian germ cell cytogenetic assay in vivo According to OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test) No Acceptable House mouse (as animal) NMRI 54 Male Not reported 12.0000000000 h yes not applicable Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is identical to the substance Diuron 206-354-4 330-54-1 3-(3,4-dichlorophenyl)-1,1-dimethylurea Diuron C9H10Cl2N2O CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration mammalian germ cell cytogenetic assay in vivo According to OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test) No Acceptable House mouse (as animal) NMRI 54 Male Not reported 6.0000000000 h yes not applicable Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is a metabolite of the substance Monuron 205-766-1 150-68-5 3-(4-chlorophenyl)-1,1-dimethylurea Monuron C9H11ClN2O CN(C)C(=O)NC1=CC=C(C=C1)Cl InChI=1S/C9H11ClN2O/c1-12(2)9(13)11-8-5-3-7(10)4-6-8/h3-6H,1-2H3,(H,11,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is a metabolite of the substance Monuron 205-766-1 150-68-5 3-(4-chlorophenyl)-1,1-dimethylurea Monuron C9H11ClN2O CN(C)C(=O)NC1=CC=C(C=C1)Cl InChI=1S/C9H11ClN2O/c1-12(2)9(13)11-8-5-3-7(10)4-6-8/h3-6H,1-2H3,(H,11,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is a metabolite of the substance Monuron 205-766-1 150-68-5 3-(4-chlorophenyl)-1,1-dimethylurea Monuron C9H11ClN2O CN(C)C(=O)NC1=CC=C(C=C1)Cl InChI=1S/C9H11ClN2O/c1-12(2)9(13)11-8-5-3-7(10)4-6-8/h3-6H,1-2H3,(H,11,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is a metabolite of the substance Monuron 205-766-1 150-68-5 3-(4-chlorophenyl)-1,1-dimethylurea Monuron C9H11ClN2O CN(C)C(=O)NC1=CC=C(C=C1)Cl InChI=1S/C9H11ClN2O/c1-12(2)9(13)11-8-5-3-7(10)4-6-8/h3-6H,1-2H3,(H,11,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle without Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is a metabolite of the substance Monuron 205-766-1 150-68-5 3-(4-chlorophenyl)-1,1-dimethylurea Monuron C9H11ClN2O CN(C)C(=O)NC1=CC=C(C=C1)Cl InChI=1S/C9H11ClN2O/c1-12(2)9(13)11-8-5-3-7(10)4-6-8/h3-6H,1-2H3,(H,11,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is a metabolite of the substance Monuron 205-766-1 150-68-5 3-(4-chlorophenyl)-1,1-dimethylurea Monuron C9H11ClN2O CN(C)C(=O)NC1=CC=C(C=C1)Cl InChI=1S/C9H11ClN2O/c1-12(2)9(13)11-8-5-3-7(10)4-6-8/h3-6H,1-2H3,(H,11,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is a metabolite of the substance Monuron 205-766-1 150-68-5 3-(4-chlorophenyl)-1,1-dimethylurea Monuron C9H11ClN2O CN(C)C(=O)NC1=CC=C(C=C1)Cl InChI=1S/C9H11ClN2O/c1-12(2)9(13)11-8-5-3-7(10)4-6-8/h3-6H,1-2H3,(H,11,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is a metabolite of the substance Monuron 205-766-1 150-68-5 3-(4-chlorophenyl)-1,1-dimethylurea Monuron C9H11ClN2O CN(C)C(=O)NC1=CC=C(C=C1)Cl InChI=1S/C9H11ClN2O/c1-12(2)9(13)11-8-5-3-7(10)4-6-8/h3-6H,1-2H3,(H,11,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle with Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is a metabolite of the substance 3-(3-chlorophenyl)-1,1-dimethyl urea 587-34-8 3-(3-chlorophenyl)-1,1-dimethylurea Not in list C9H11ClN2O CN(C)C(=O)NC1=CC(=CC=C1)Cl InChI=1S/C9H11ClN2O/c1-12(2)9(13)11-8-5-3-4-7(10)6-8/h3-6H,1-2H3,(H,11,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle with Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is a metabolite of the substance 3-(3-chlorophenyl)-1,1-dimethyl urea 587-34-8 3-(3-chlorophenyl)-1,1-dimethylurea Not in list C9H11ClN2O CN(C)C(=O)NC1=CC(=CC=C1)Cl InChI=1S/C9H11ClN2O/c1-12(2)9(13)11-8-5-3-4-7(10)6-8/h3-6H,1-2H3,(H,11,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is a metabolite of the substance 3-(3-chlorophenyl)-1,1-dimethyl urea 587-34-8 3-(3-chlorophenyl)-1,1-dimethylurea Not in list C9H11ClN2O CN(C)C(=O)NC1=CC(=CC=C1)Cl InChI=1S/C9H11ClN2O/c1-12(2)9(13)11-8-5-3-4-7(10)6-8/h3-6H,1-2H3,(H,11,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle without Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is a metabolite of the substance 3-(3-chlorophenyl)-1,1-dimethyl urea 587-34-8 3-(3-chlorophenyl)-1,1-dimethylurea Not in list C9H11ClN2O CN(C)C(=O)NC1=CC(=CC=C1)Cl InChI=1S/C9H11ClN2O/c1-12(2)9(13)11-8-5-3-4-7(10)6-8/h3-6H,1-2H3,(H,11,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is a metabolite of the substance 3-(3-chlorophenyl)-1,1-dimethyl urea 587-34-8 3-(3-chlorophenyl)-1,1-dimethylurea Not in list C9H11ClN2O CN(C)C(=O)NC1=CC(=CC=C1)Cl InChI=1S/C9H11ClN2O/c1-12(2)9(13)11-8-5-3-4-7(10)6-8/h3-6H,1-2H3,(H,11,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is a metabolite of the substance 3-(3-chlorophenyl)-1,1-dimethyl urea 587-34-8 3-(3-chlorophenyl)-1,1-dimethylurea Not in list C9H11ClN2O CN(C)C(=O)NC1=CC(=CC=C1)Cl InChI=1S/C9H11ClN2O/c1-12(2)9(13)11-8-5-3-4-7(10)6-8/h3-6H,1-2H3,(H,11,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is a metabolite of the substance 3-(3-chlorophenyl)-1,1-dimethyl urea 587-34-8 3-(3-chlorophenyl)-1,1-dimethylurea Not in list C9H11ClN2O CN(C)C(=O)NC1=CC(=CC=C1)Cl InChI=1S/C9H11ClN2O/c1-12(2)9(13)11-8-5-3-4-7(10)6-8/h3-6H,1-2H3,(H,11,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is a metabolite of the substance 3-(3-chlorophenyl)-1,1-dimethyl urea 587-34-8 3-(3-chlorophenyl)-1,1-dimethylurea Not in list C9H11ClN2O CN(C)C(=O)NC1=CC(=CC=C1)Cl InChI=1S/C9H11ClN2O/c1-12(2)9(13)11-8-5-3-4-7(10)6-8/h3-6H,1-2H3,(H,11,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is a metabolite of the substance (3,5-dichlorophenyl)-1,1-dimethyl urea 10290-38-7 3-(3,5-dichlorophenyl)-1,1-dimethylurea Not in list C9H10Cl2N2O CN(C)C(=O)NC1=CC(=CC(=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-8-4-6(10)3-7(11)5-8/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle without Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is a metabolite of the substance (3,5-dichlorophenyl)-1,1-dimethyl urea 10290-38-7 3-(3,5-dichlorophenyl)-1,1-dimethylurea Not in list C9H10Cl2N2O CN(C)C(=O)NC1=CC(=CC(=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-8-4-6(10)3-7(11)5-8/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is a metabolite of the substance (3,5-dichlorophenyl)-1,1-dimethyl urea 10290-38-7 3-(3,5-dichlorophenyl)-1,1-dimethylurea Not in list C9H10Cl2N2O CN(C)C(=O)NC1=CC(=CC(=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-8-4-6(10)3-7(11)5-8/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle with Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is a metabolite of the substance (3,5-dichlorophenyl)-1,1-dimethyl urea 10290-38-7 3-(3,5-dichlorophenyl)-1,1-dimethylurea Not in list C9H10Cl2N2O CN(C)C(=O)NC1=CC(=CC(=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-8-4-6(10)3-7(11)5-8/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is a metabolite of the substance (3,5-dichlorophenyl)-1,1-dimethyl urea 10290-38-7 3-(3,5-dichlorophenyl)-1,1-dimethylurea Not in list C9H10Cl2N2O CN(C)C(=O)NC1=CC(=CC(=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-8-4-6(10)3-7(11)5-8/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is a metabolite of the substance (3,5-dichlorophenyl)-1,1-dimethyl urea 10290-38-7 3-(3,5-dichlorophenyl)-1,1-dimethylurea Not in list C9H10Cl2N2O CN(C)C(=O)NC1=CC(=CC(=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-8-4-6(10)3-7(11)5-8/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is a metabolite of the substance (3,5-dichlorophenyl)-1,1-dimethyl urea 10290-38-7 3-(3,5-dichlorophenyl)-1,1-dimethylurea Not in list C9H10Cl2N2O CN(C)C(=O)NC1=CC(=CC(=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-8-4-6(10)3-7(11)5-8/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Diuron 206-354-4 330-54-1 single chemical entity Component is a metabolite of the substance (3,5-dichlorophenyl)-1,1-dimethyl urea 10290-38-7 3-(3,5-dichlorophenyl)-1,1-dimethylurea Not in list C9H10Cl2N2O CN(C)C(=O)NC1=CC(=CC(=C1)Cl)Cl InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-8-4-6(10)3-7(11)5-8/h3-5H,1-2H3,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Denmark Diuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron 28Jan2005 2005 doi:10.2903/j.efsa.2005.25r
+Cycloxydim 101205-02-1 single chemical entity Component is identical to the substance Cycloxydim 101205-02-1 2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one Cycloxydim C17H27NO3S CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2 InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is identical to the substance Cycloxydim 101205-02-1 2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one Cycloxydim C17H27NO3S CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2 InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is identical to the substance Cycloxydim 101205-02-1 2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one Cycloxydim C17H27NO3S CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2 InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is identical to the substance Cycloxydim 101205-02-1 2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one Cycloxydim C17H27NO3S CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2 InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is identical to the substance Cycloxydim 101205-02-1 2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one Cycloxydim C17H27NO3S CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2 InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is identical to the substance Cycloxydim 101205-02-1 2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one Cycloxydim C17H27NO3S CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2 InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is identical to the substance Cycloxydim 101205-02-1 2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one Cycloxydim C17H27NO3S CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2 InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is identical to the substance Cycloxydim 101205-02-1 2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one Cycloxydim C17H27NO3S CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2 InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is identical to the substance Cycloxydim 101205-02-1 2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one Cycloxydim C17H27NO3S CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2 InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is identical to the substance Cycloxydim 101205-02-1 2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one Cycloxydim C17H27NO3S CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2 InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is identical to the substance Cycloxydim 101205-02-1 2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one Cycloxydim C17H27NO3S CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2 InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is identical to the substance Cycloxydim 101205-02-1 2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one Cycloxydim C17H27NO3S CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2 InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is identical to the substance Cycloxydim 101205-02-1 2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one Cycloxydim C17H27NO3S CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2 InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is identical to the substance Cycloxydim 101205-02-1 2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one Cycloxydim C17H27NO3S CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2 InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is identical to the substance Cycloxydim 101205-02-1 2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one Cycloxydim C17H27NO3S CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2 InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is identical to the substance Cycloxydim 101205-02-1 2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one Cycloxydim C17H27NO3S CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2 InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is identical to the substance Cycloxydim 101205-02-1 2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one Cycloxydim C17H27NO3S CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2 InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is identical to the substance Cycloxydim 101205-02-1 2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one Cycloxydim C17H27NO3S CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2 InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is identical to the substance Cycloxydim 101205-02-1 2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one Cycloxydim C17H27NO3S CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2 InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+ organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is identical to the substance Cycloxydim 101205-02-1 2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one Cycloxydim C17H27NO3S CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2 InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+ organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is identical to the substance Cycloxydim 101205-02-1 2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one Cycloxydim C17H27NO3S CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2 InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+ organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is identical to the substance Cycloxydim 101205-02-1 2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one Cycloxydim C17H27NO3S CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2 InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+ organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is identical to the substance Cycloxydim 101205-02-1 2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one Cycloxydim C17H27NO3S CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2 InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+ organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Positive no information RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is identical to the substance Cycloxydim 101205-02-1 2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one Cycloxydim C17H27NO3S CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2 InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+ organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is identical to the substance Cycloxydim 101205-02-1 2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one Cycloxydim C17H27NO3S CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2 InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+ organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is identical to the substance Cycloxydim 101205-02-1 2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one Cycloxydim C17H27NO3S CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2 InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+ organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Positive RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is identical to the substance Cycloxydim 101205-02-1 2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one Cycloxydim C17H27NO3S CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2 InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+ organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Positive RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is identical to the substance Cycloxydim 101205-02-1 2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one Cycloxydim C17H27NO3S CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2 InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+ organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is identical to the substance Cycloxydim 101205-02-1 2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one Cycloxydim C17H27NO3S CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2 InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+ organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes without Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is identical to the substance Cycloxydim 101205-02-1 2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one Cycloxydim C17H27NO3S CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2 InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+ organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is identical to the substance Cycloxydim 101205-02-1 2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one Cycloxydim C17H27NO3S CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2 InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+ organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 16.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is identical to the substance Cycloxydim 101205-02-1 2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one Cycloxydim C17H27NO3S CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2 InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+ organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is identical to the substance Cycloxydim 101205-02-1 2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one Cycloxydim C17H27NO3S CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2 InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+ organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is identical to the substance Cycloxydim 101205-02-1 2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one Cycloxydim C17H27NO3S CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2 InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+ organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Hamster (as animal) Chinese 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is identical to the substance Cycloxydim 101205-02-1 2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one Cycloxydim C17H27NO3S CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2 InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+ organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Hamster (as animal) Chinese 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is identical to the substance Cycloxydim 101205-02-1 2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one Cycloxydim C17H27NO3S CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2 InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+ organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Hamster (as animal) Chinese 10 Male/Female oral: gavage 6.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 2-[1-(ethoxyimino)butyl]-3,5-dihydroxy-5-(3-thianyl)-2-cycloexene-1-one S-oxide 3-{4-[(1E)-N-ethoxybutanimidoyl]-1,3-dihydroxy-5-oxocyclohex-3-en-1-yl}-1ï¬4-thian-1-one Not in list C17H27NO5S O=S1CCCC(C1)C2(O)CC(=O)C(C(\CCC)=N\OCC)=C(O)C2 InChI=1/C17H27NO5S/c1-3-6-13(18-23-4-2)16-14(19)9-17(21,10-15(16)20)12-7-5-8-24(22)11-12/h12,19,21H,3-11H2,1-2H3/b18-13+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 2-[1-(ethoxyimino)butyl]-3,5-dihydroxy-5-(3-thianyl)-2-cycloexene-1-one S-oxide 3-{4-[(1E)-N-ethoxybutanimidoyl]-1,3-dihydroxy-5-oxocyclohex-3-en-1-yl}-1ï¬4-thian-1-one Not in list C17H27NO5S O=S1CCCC(C1)C2(O)CC(=O)C(C(\CCC)=N\OCC)=C(O)C2 InChI=1/C17H27NO5S/c1-3-6-13(18-23-4-2)16-14(19)9-17(21,10-15(16)20)12-7-5-8-24(22)11-12/h12,19,21H,3-11H2,1-2H3/b18-13+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 2-[1-(ethoxyimino)butyl]-3,5-dihydroxy-5-(3-thianyl)-2-cycloexene-1-one S-oxide 3-{4-[(1E)-N-ethoxybutanimidoyl]-1,3-dihydroxy-5-oxocyclohex-3-en-1-yl}-1ï¬4-thian-1-one Not in list C17H27NO5S O=S1CCCC(C1)C2(O)CC(=O)C(C(\CCC)=N\OCC)=C(O)C2 InChI=1/C17H27NO5S/c1-3-6-13(18-23-4-2)16-14(19)9-17(21,10-15(16)20)12-7-5-8-24(22)11-12/h12,19,21H,3-11H2,1-2H3/b18-13+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 2-[1-(ethoxyimino)butyl]-3,5-dihydroxy-5-(3-thianyl)-2-cycloexene-1-one S-oxide 3-{4-[(1E)-N-ethoxybutanimidoyl]-1,3-dihydroxy-5-oxocyclohex-3-en-1-yl}-1ï¬4-thian-1-one Not in list C17H27NO5S O=S1CCCC(C1)C2(O)CC(=O)C(C(\CCC)=N\OCC)=C(O)C2 InChI=1/C17H27NO5S/c1-3-6-13(18-23-4-2)16-14(19)9-17(21,10-15(16)20)12-7-5-8-24(22)11-12/h12,19,21H,3-11H2,1-2H3/b18-13+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 2-[1-(ethoxyimino)butyl]-3,5-dihydroxy-5-(3-thianyl)-2-cycloexene-1-one S-oxide 3-{4-[(1E)-N-ethoxybutanimidoyl]-1,3-dihydroxy-5-oxocyclohex-3-en-1-yl}-1ï¬4-thian-1-one Not in list C17H27NO5S O=S1CCCC(C1)C2(O)CC(=O)C(C(\CCC)=N\OCC)=C(O)C2 InChI=1/C17H27NO5S/c1-3-6-13(18-23-4-2)16-14(19)9-17(21,10-15(16)20)12-7-5-8-24(22)11-12/h12,19,21H,3-11H2,1-2H3/b18-13+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 2-[1-(ethoxyimino)butyl]-3,5-dihydroxy-5-(3-thianyl)-2-cycloexene-1-one S-oxide 3-{4-[(1E)-N-ethoxybutanimidoyl]-1,3-dihydroxy-5-oxocyclohex-3-en-1-yl}-1ï¬4-thian-1-one Not in list C17H27NO5S O=S1CCCC(C1)C2(O)CC(=O)C(C(\CCC)=N\OCC)=C(O)C2 InChI=1/C17H27NO5S/c1-3-6-13(18-23-4-2)16-14(19)9-17(21,10-15(16)20)12-7-5-8-24(22)11-12/h12,19,21H,3-11H2,1-2H3/b18-13+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 2-[1-(ethoxyimino)butyl]-3,5-dihydroxy-5-(3-thianyl)-2-cycloexene-1-one S-oxide 3-{4-[(1E)-N-ethoxybutanimidoyl]-1,3-dihydroxy-5-oxocyclohex-3-en-1-yl}-1ï¬4-thian-1-one Not in list C17H27NO5S O=S1CCCC(C1)C2(O)CC(=O)C(C(\CCC)=N\OCC)=C(O)C2 InChI=1/C17H27NO5S/c1-3-6-13(18-23-4-2)16-14(19)9-17(21,10-15(16)20)12-7-5-8-24(22)11-12/h12,19,21H,3-11H2,1-2H3/b18-13+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 2-[1-(ethoxyimino)butyl]-3,5-dihydroxy-5-(3-thianyl)-2-cycloexene-1-one S-oxide 3-{4-[(1E)-N-ethoxybutanimidoyl]-1,3-dihydroxy-5-oxocyclohex-3-en-1-yl}-1ï¬4-thian-1-one Not in list C17H27NO5S O=S1CCCC(C1)C2(O)CC(=O)C(C(\CCC)=N\OCC)=C(O)C2 InChI=1/C17H27NO5S/c1-3-6-13(18-23-4-2)16-14(19)9-17(21,10-15(16)20)12-7-5-8-24(22)11-12/h12,19,21H,3-11H2,1-2H3/b18-13+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 2-[1-(ethoxyimino)butyl]-3,5-dihydroxy-5-(3-thianyl)-2-cycloexene-1-one S-oxide 3-{4-[(1E)-N-ethoxybutanimidoyl]-1,3-dihydroxy-5-oxocyclohex-3-en-1-yl}-1ï¬4-thian-1-one Not in list C17H27NO5S O=S1CCCC(C1)C2(O)CC(=O)C(C(\CCC)=N\OCC)=C(O)C2 InChI=1/C17H27NO5S/c1-3-6-13(18-23-4-2)16-14(19)9-17(21,10-15(16)20)12-7-5-8-24(22)11-12/h12,19,21H,3-11H2,1-2H3/b18-13+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 2-[1-(ethoxyimino)butyl]-3,5-dihydroxy-5-(3-thianyl)-2-cycloexene-1-one S-oxide 3-{4-[(1E)-N-ethoxybutanimidoyl]-1,3-dihydroxy-5-oxocyclohex-3-en-1-yl}-1ï¬4-thian-1-one Not in list C17H27NO5S O=S1CCCC(C1)C2(O)CC(=O)C(C(\CCC)=N\OCC)=C(O)C2 InChI=1/C17H27NO5S/c1-3-6-13(18-23-4-2)16-14(19)9-17(21,10-15(16)20)12-7-5-8-24(22)11-12/h12,19,21H,3-11H2,1-2H3/b18-13+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 2-[1-(ethoxyimino)butyl]-3,5-dihydroxy-5-(3-thianyl)-2-cycloexene-1-one S-oxide 3-{4-[(1E)-N-ethoxybutanimidoyl]-1,3-dihydroxy-5-oxocyclohex-3-en-1-yl}-1ï¬4-thian-1-one Not in list C17H27NO5S O=S1CCCC(C1)C2(O)CC(=O)C(C(\CCC)=N\OCC)=C(O)C2 InChI=1/C17H27NO5S/c1-3-6-13(18-23-4-2)16-14(19)9-17(21,10-15(16)20)12-7-5-8-24(22)11-12/h12,19,21H,3-11H2,1-2H3/b18-13+ organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 2-[1-(ethoxyimino)butyl]-3,5-dihydroxy-5-(3-thianyl)-2-cycloexene-1-one S-oxide 3-{4-[(1E)-N-ethoxybutanimidoyl]-1,3-dihydroxy-5-oxocyclohex-3-en-1-yl}-1ï¬4-thian-1-one Not in list C17H27NO5S O=S1CCCC(C1)C2(O)CC(=O)C(C(\CCC)=N\OCC)=C(O)C2 InChI=1/C17H27NO5S/c1-3-6-13(18-23-4-2)16-14(19)9-17(21,10-15(16)20)12-7-5-8-24(22)11-12/h12,19,21H,3-11H2,1-2H3/b18-13+ organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 2-[1-(ethoxyimino)butyl]-3,5-dihydroxy-5-(3-thianyl)-2-cycloexene-1-one S-oxide 3-{4-[(1E)-N-ethoxybutanimidoyl]-1,3-dihydroxy-5-oxocyclohex-3-en-1-yl}-1ï¬4-thian-1-one Not in list C17H27NO5S O=S1CCCC(C1)C2(O)CC(=O)C(C(\CCC)=N\OCC)=C(O)C2 InChI=1/C17H27NO5S/c1-3-6-13(18-23-4-2)16-14(19)9-17(21,10-15(16)20)12-7-5-8-24(22)11-12/h12,19,21H,3-11H2,1-2H3/b18-13+ organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 2-[1-(ethoxyimino)butyl]-3,5-dihydroxy-5-(3-thianyl)-2-cycloexene-1-one S-oxide 3-{4-[(1E)-N-ethoxybutanimidoyl]-1,3-dihydroxy-5-oxocyclohex-3-en-1-yl}-1ï¬4-thian-1-one Not in list C17H27NO5S O=S1CCCC(C1)C2(O)CC(=O)C(C(\CCC)=N\OCC)=C(O)C2 InChI=1/C17H27NO5S/c1-3-6-13(18-23-4-2)16-14(19)9-17(21,10-15(16)20)12-7-5-8-24(22)11-12/h12,19,21H,3-11H2,1-2H3/b18-13+ organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 2-[1-(ethylimino)butyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)-2-cyclohexen-1-one S-oxide 2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(1-oxidotetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one Not in list C17H27NO4S O=S1CCCC(C1)C2CC(=O)C(C(\CCC)=N\OCC)=C(O)C2 InChI=1/C17H27NO4S/c1-3-6-14(18-22-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-23(21)11-12/h12-13,19H,3-11H2,1-2H3/b18-14+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 2-[1-(ethylimino)butyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)-2-cyclohexen-1-one S-oxide 2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(1-oxidotetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one Not in list C17H27NO4S O=S1CCCC(C1)C2CC(=O)C(C(\CCC)=N\OCC)=C(O)C2 InChI=1/C17H27NO4S/c1-3-6-14(18-22-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-23(21)11-12/h12-13,19H,3-11H2,1-2H3/b18-14+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 2-[1-(ethylimino)butyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)-2-cyclohexen-1-one S-oxide 2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(1-oxidotetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one Not in list C17H27NO4S O=S1CCCC(C1)C2CC(=O)C(C(\CCC)=N\OCC)=C(O)C2 InChI=1/C17H27NO4S/c1-3-6-14(18-22-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-23(21)11-12/h12-13,19H,3-11H2,1-2H3/b18-14+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 2-[1-(ethylimino)butyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)-2-cyclohexen-1-one S-oxide 2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(1-oxidotetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one Not in list C17H27NO4S O=S1CCCC(C1)C2CC(=O)C(C(\CCC)=N\OCC)=C(O)C2 InChI=1/C17H27NO4S/c1-3-6-14(18-22-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-23(21)11-12/h12-13,19H,3-11H2,1-2H3/b18-14+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 2-[1-(ethylimino)butyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)-2-cyclohexen-1-one S-oxide 2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(1-oxidotetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one Not in list C17H27NO4S O=S1CCCC(C1)C2CC(=O)C(C(\CCC)=N\OCC)=C(O)C2 InChI=1/C17H27NO4S/c1-3-6-14(18-22-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-23(21)11-12/h12-13,19H,3-11H2,1-2H3/b18-14+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 2-[1-(ethylimino)butyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)-2-cyclohexen-1-one S-oxide 2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(1-oxidotetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one Not in list C17H27NO4S O=S1CCCC(C1)C2CC(=O)C(C(\CCC)=N\OCC)=C(O)C2 InChI=1/C17H27NO4S/c1-3-6-14(18-22-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-23(21)11-12/h12-13,19H,3-11H2,1-2H3/b18-14+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 2-[1-(ethylimino)butyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)-2-cyclohexen-1-one S-oxide 2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(1-oxidotetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one Not in list C17H27NO4S O=S1CCCC(C1)C2CC(=O)C(C(\CCC)=N\OCC)=C(O)C2 InChI=1/C17H27NO4S/c1-3-6-14(18-22-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-23(21)11-12/h12-13,19H,3-11H2,1-2H3/b18-14+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 2-[1-(ethylimino)butyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)-2-cyclohexen-1-one S-oxide 2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(1-oxidotetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one Not in list C17H27NO4S O=S1CCCC(C1)C2CC(=O)C(C(\CCC)=N\OCC)=C(O)C2 InChI=1/C17H27NO4S/c1-3-6-14(18-22-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-23(21)11-12/h12-13,19H,3-11H2,1-2H3/b18-14+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 2-[1-(ethylimino)butyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)-2-cyclohexen-1-one S-oxide 2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(1-oxidotetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one Not in list C17H27NO4S O=S1CCCC(C1)C2CC(=O)C(C(\CCC)=N\OCC)=C(O)C2 InChI=1/C17H27NO4S/c1-3-6-14(18-22-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-23(21)11-12/h12-13,19H,3-11H2,1-2H3/b18-14+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 2-[1-(ethylimino)butyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)-2-cyclohexen-1-one S-oxide 2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(1-oxidotetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one Not in list C17H27NO4S O=S1CCCC(C1)C2CC(=O)C(C(\CCC)=N\OCC)=C(O)C2 InChI=1/C17H27NO4S/c1-3-6-14(18-22-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-23(21)11-12/h12-13,19H,3-11H2,1-2H3/b18-14+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 3-(3-thianyl)glutaric acid S-dioxide 3-(1,1-dioxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid Not in list C10H16O6S O=S1(=O)CCCC(C1)C(CC(=O)O)CC(=O)O InChI=1/C10H16O6S/c11-9(12)4-8(5-10(13)14)7-2-1-3-17(15,16)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 3-(3-thianyl)glutaric acid S-dioxide 3-(1,1-dioxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid Not in list C10H16O6S O=S1(=O)CCCC(C1)C(CC(=O)O)CC(=O)O InChI=1/C10H16O6S/c11-9(12)4-8(5-10(13)14)7-2-1-3-17(15,16)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 3-(3-thianyl)glutaric acid S-dioxide 3-(1,1-dioxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid Not in list C10H16O6S O=S1(=O)CCCC(C1)C(CC(=O)O)CC(=O)O InChI=1/C10H16O6S/c11-9(12)4-8(5-10(13)14)7-2-1-3-17(15,16)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 3-(3-thianyl)glutaric acid S-dioxide 3-(1,1-dioxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid Not in list C10H16O6S O=S1(=O)CCCC(C1)C(CC(=O)O)CC(=O)O InChI=1/C10H16O6S/c11-9(12)4-8(5-10(13)14)7-2-1-3-17(15,16)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 3-(3-thianyl)glutaric acid S-dioxide 3-(1,1-dioxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid Not in list C10H16O6S O=S1(=O)CCCC(C1)C(CC(=O)O)CC(=O)O InChI=1/C10H16O6S/c11-9(12)4-8(5-10(13)14)7-2-1-3-17(15,16)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 3-(3-thianyl)glutaric acid S-dioxide 3-(1,1-dioxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid Not in list C10H16O6S O=S1(=O)CCCC(C1)C(CC(=O)O)CC(=O)O InChI=1/C10H16O6S/c11-9(12)4-8(5-10(13)14)7-2-1-3-17(15,16)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 3-(3-thianyl)glutaric acid S-dioxide 3-(1,1-dioxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid Not in list C10H16O6S O=S1(=O)CCCC(C1)C(CC(=O)O)CC(=O)O InChI=1/C10H16O6S/c11-9(12)4-8(5-10(13)14)7-2-1-3-17(15,16)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 3-(3-thianyl)glutaric acid S-dioxide 3-(1,1-dioxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid Not in list C10H16O6S O=S1(=O)CCCC(C1)C(CC(=O)O)CC(=O)O InChI=1/C10H16O6S/c11-9(12)4-8(5-10(13)14)7-2-1-3-17(15,16)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle with Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 3-(3-thianyl)glutaric acid S-dioxide 3-(1,1-dioxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid Not in list C10H16O6S O=S1(=O)CCCC(C1)C(CC(=O)O)CC(=O)O InChI=1/C10H16O6S/c11-9(12)4-8(5-10(13)14)7-2-1-3-17(15,16)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 3-(3-thianyl)glutaric acid S-dioxide 3-(1,1-dioxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid Not in list C10H16O6S O=S1(=O)CCCC(C1)C(CC(=O)O)CC(=O)O InChI=1/C10H16O6S/c11-9(12)4-8(5-10(13)14)7-2-1-3-17(15,16)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 3-(3-thianyl)glutaric acid S-dioxide 3-(1,1-dioxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid Not in list C10H16O6S O=S1(=O)CCCC(C1)C(CC(=O)O)CC(=O)O InChI=1/C10H16O6S/c11-9(12)4-8(5-10(13)14)7-2-1-3-17(15,16)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 3-(3-thianyl)glutaric acid S-dioxide 3-(1,1-dioxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid Not in list C10H16O6S O=S1(=O)CCCC(C1)C(CC(=O)O)CC(=O)O InChI=1/C10H16O6S/c11-9(12)4-8(5-10(13)14)7-2-1-3-17(15,16)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 3-(3-thianyl)glutaric acid S-dioxide 3-(1,1-dioxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid Not in list C10H16O6S O=S1(=O)CCCC(C1)C(CC(=O)O)CC(=O)O InChI=1/C10H16O6S/c11-9(12)4-8(5-10(13)14)7-2-1-3-17(15,16)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 3-(3-thianyl)glutaric acid S-dioxide 3-(1,1-dioxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid Not in list C10H16O6S O=S1(=O)CCCC(C1)C(CC(=O)O)CC(=O)O InChI=1/C10H16O6S/c11-9(12)4-8(5-10(13)14)7-2-1-3-17(15,16)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid 3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid Not in list C10H16O5S O=S1CCCC(C1)C(CC(=O)O)CC(=O)O InChI=1/C10H16O5S/c11-9(12)4-8(5-10(13)14)7-2-1-3-16(15)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid 3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid Not in list C10H16O5S O=S1CCCC(C1)C(CC(=O)O)CC(=O)O InChI=1/C10H16O5S/c11-9(12)4-8(5-10(13)14)7-2-1-3-16(15)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid 3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid Not in list C10H16O5S O=S1CCCC(C1)C(CC(=O)O)CC(=O)O InChI=1/C10H16O5S/c11-9(12)4-8(5-10(13)14)7-2-1-3-16(15)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid 3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid Not in list C10H16O5S O=S1CCCC(C1)C(CC(=O)O)CC(=O)O InChI=1/C10H16O5S/c11-9(12)4-8(5-10(13)14)7-2-1-3-16(15)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid 3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid Not in list C10H16O5S O=S1CCCC(C1)C(CC(=O)O)CC(=O)O InChI=1/C10H16O5S/c11-9(12)4-8(5-10(13)14)7-2-1-3-16(15)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid 3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid Not in list C10H16O5S O=S1CCCC(C1)C(CC(=O)O)CC(=O)O InChI=1/C10H16O5S/c11-9(12)4-8(5-10(13)14)7-2-1-3-16(15)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid 3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid Not in list C10H16O5S O=S1CCCC(C1)C(CC(=O)O)CC(=O)O InChI=1/C10H16O5S/c11-9(12)4-8(5-10(13)14)7-2-1-3-16(15)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid 3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid Not in list C10H16O5S O=S1CCCC(C1)C(CC(=O)O)CC(=O)O InChI=1/C10H16O5S/c11-9(12)4-8(5-10(13)14)7-2-1-3-16(15)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid 3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid Not in list C10H16O5S O=S1CCCC(C1)C(CC(=O)O)CC(=O)O InChI=1/C10H16O5S/c11-9(12)4-8(5-10(13)14)7-2-1-3-16(15)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid 3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid Not in list C10H16O5S O=S1CCCC(C1)C(CC(=O)O)CC(=O)O InChI=1/C10H16O5S/c11-9(12)4-8(5-10(13)14)7-2-1-3-16(15)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Austria Cycloxydim 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is identical to the substance Ethofumesate 247-525-3 26225-79-6 (2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate Ethofumesate C13H18O5S CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is identical to the substance Ethofumesate 247-525-3 26225-79-6 (2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate Ethofumesate C13H18O5S CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) CM881 Not reported yes, concurrent vehicle with Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is identical to the substance Ethofumesate 247-525-3 26225-79-6 (2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate Ethofumesate C13H18O5S CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) CM881 Not reported yes, concurrent vehicle without Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is identical to the substance Ethofumesate 247-525-3 26225-79-6 (2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate Ethofumesate C13H18O5S CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is identical to the substance Ethofumesate 247-525-3 26225-79-6 (2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate Ethofumesate C13H18O5S CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is identical to the substance Ethofumesate 247-525-3 26225-79-6 (2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate Ethofumesate C13H18O5S CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is identical to the substance Ethofumesate 247-525-3 26225-79-6 (2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate Ethofumesate C13H18O5S CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) CM891 Not reported yes, concurrent vehicle with Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is identical to the substance Ethofumesate 247-525-3 26225-79-6 (2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate Ethofumesate C13H18O5S CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is identical to the substance Ethofumesate 247-525-3 26225-79-6 (2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate Ethofumesate C13H18O5S CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) CM891 Not reported yes, concurrent vehicle without Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is identical to the substance Ethofumesate 247-525-3 26225-79-6 (2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate Ethofumesate C13H18O5S CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is identical to the substance Ethofumesate 247-525-3 26225-79-6 (2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate Ethofumesate C13H18O5S CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is identical to the substance Ethofumesate 247-525-3 26225-79-6 (2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate Ethofumesate C13H18O5S CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is identical to the substance Ethofumesate 247-525-3 26225-79-6 (2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate Ethofumesate C13H18O5S CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is identical to the substance Ethofumesate 247-525-3 26225-79-6 (2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate Ethofumesate C13H18O5S CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is identical to the substance Ethofumesate 247-525-3 26225-79-6 (2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate Ethofumesate C13H18O5S CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is identical to the substance Ethofumesate 247-525-3 26225-79-6 (2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate Ethofumesate C13H18O5S CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is identical to the substance Ethofumesate 247-525-3 26225-79-6 (2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate Ethofumesate C13H18O5S CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is identical to the substance Ethofumesate 247-525-3 26225-79-6 (2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate Ethofumesate C13H18O5S CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is identical to the substance Ethofumesate 247-525-3 26225-79-6 (2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate Ethofumesate C13H18O5S CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is identical to the substance Ethofumesate 247-525-3 26225-79-6 (2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate Ethofumesate C13H18O5S CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is identical to the substance Ethofumesate 247-525-3 26225-79-6 (2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate Ethofumesate C13H18O5S CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is identical to the substance Ethofumesate 247-525-3 26225-79-6 (2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate Ethofumesate C13H18O5S CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is identical to the substance Ethofumesate 247-525-3 26225-79-6 (2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate Ethofumesate C13H18O5S CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is identical to the substance Ethofumesate 247-525-3 26225-79-6 (2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate Ethofumesate C13H18O5S CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is identical to the substance Ethofumesate 247-525-3 26225-79-6 (2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate Ethofumesate C13H18O5S CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is identical to the substance Ethofumesate 247-525-3 26225-79-6 (2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate Ethofumesate C13H18O5S CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is identical to the substance Ethofumesate 247-525-3 26225-79-6 (2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate Ethofumesate C13H18O5S CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is identical to the substance Ethofumesate 247-525-3 26225-79-6 (2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate Ethofumesate C13H18O5S CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is identical to the substance Ethofumesate 247-525-3 26225-79-6 (2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate Ethofumesate C13H18O5S CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is identical to the substance Ethofumesate 247-525-3 26225-79-6 (2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate Ethofumesate C13H18O5S CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is identical to the substance Ethofumesate 247-525-3 26225-79-6 (2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate Ethofumesate C13H18O5S CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is identical to the substance Ethofumesate 247-525-3 26225-79-6 (2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate Ethofumesate C13H18O5S CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is identical to the substance Ethofumesate 247-525-3 26225-79-6 (2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate Ethofumesate C13H18O5S CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is identical to the substance Ethofumesate 247-525-3 26225-79-6 (2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate Ethofumesate C13H18O5S CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is identical to the substance Ethofumesate 247-525-3 26225-79-6 (2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate Ethofumesate C13H18O5S CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is identical to the substance Ethofumesate 247-525-3 26225-79-6 (2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate Ethofumesate C13H18O5S CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is identical to the substance Ethofumesate 247-525-3 26225-79-6 (2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate Ethofumesate C13H18O5S CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is identical to the substance Ethofumesate 247-525-3 26225-79-6 (2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate Ethofumesate C13H18O5S CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is identical to the substance Ethofumesate 247-525-3 26225-79-6 (2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate Ethofumesate C13H18O5S CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is identical to the substance Ethofumesate 247-525-3 26225-79-6 (2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate Ethofumesate C13H18O5S CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is identical to the substance Ethofumesate 247-525-3 26225-79-6 (2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate Ethofumesate C13H18O5S CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is identical to the substance Ethofumesate 247-525-3 26225-79-6 (2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate Ethofumesate C13H18O5S CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is identical to the substance Ethofumesate 247-525-3 26225-79-6 (2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate Ethofumesate C13H18O5S CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is identical to the substance Ethofumesate 247-525-3 26225-79-6 (2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate Ethofumesate C13H18O5S CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is identical to the substance Ethofumesate 247-525-3 26225-79-6 (2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate Ethofumesate C13H18O5S CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is identical to the substance Ethofumesate 247-525-3 26225-79-6 (2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate Ethofumesate C13H18O5S CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is identical to the substance Ethofumesate 247-525-3 26225-79-6 (2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate Ethofumesate C13H18O5S CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is identical to the substance Ethofumesate 247-525-3 26225-79-6 (2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate Ethofumesate C13H18O5S CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is identical to the substance Ethofumesate 247-525-3 26225-79-6 (2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate Ethofumesate C13H18O5S CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is identical to the substance Ethofumesate 247-525-3 26225-79-6 (2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate Ethofumesate C13H18O5S CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is identical to the substance Ethofumesate 247-525-3 26225-79-6 (2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate Ethofumesate C13H18O5S CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is identical to the substance Ethofumesate 247-525-3 26225-79-6 (2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate Ethofumesate C13H18O5S CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 72.0000000000 h yes, concurrent vehicle not applicable Negative indirect-toxicokinetic investigations RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is identical to the substance Ethofumesate 247-525-3 26225-79-6 (2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate Ethofumesate C13H18O5S CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect-toxicokinetic investigations RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is identical to the substance Ethofumesate 247-525-3 26225-79-6 (2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate Ethofumesate C13H18O5S CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect-toxicokinetic investigations RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is identical to the substance Ethofumesate 247-525-3 26225-79-6 (2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate Ethofumesate C13H18O5S CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 10 Male/Female oral: unspecified 72.0000000000 h yes, concurrent vehicle not applicable Negative indirect-toxicokinetic investigations RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is identical to the substance Ethofumesate 247-525-3 26225-79-6 (2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate Ethofumesate C13H18O5S CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 10 Male/Female oral: unspecified 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect-toxicokinetic investigations RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is identical to the substance Ethofumesate 247-525-3 26225-79-6 (2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate Ethofumesate C13H18O5S CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 10 Male/Female oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect-toxicokinetic investigations RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is identical to the substance Ethofumesate 247-525-3 26225-79-6 (2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate Ethofumesate C13H18O5S CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Swiss 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Positive indirect evidence-systemic toxicity RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is identical to the substance Ethofumesate 247-525-3 26225-79-6 (2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate Ethofumesate C13H18O5S CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Swiss 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Positive indirect evidence-systemic toxicity RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is identical to the substance Ethofumesate 247-525-3 26225-79-6 (2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate Ethofumesate C13H18O5S CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) Swiss 10 Male/Female oral: gavage 24.0000000000 h yes not applicable Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is identical to the substance Ethofumesate 247-525-3 26225-79-6 (2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate Ethofumesate C13H18O5S CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) Yes Acceptable Rat (as animal) Wistar Male oral: gavage yes not applicable Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is a metabolite of the substance 2-{2-hydroxy-5-[(methylsulfonyl)methyl]phenyl}-2-methylpropanoic acid 2-{2-hydroxy-5-[(methylsulfonyl)oxy]phenyl}-2-methylpropanoic acid Not in list C11H14O6S CC(C)(c1cc(ccc1O)OS(C)(=O)=O)C(=O)O InChI=1/C11H14O6S/c1-11(2,10(13)14)8-6-7(4-5-9(8)12)17-18(3,15)16/h4-6,12H,1-3H3,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes with Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is a metabolite of the substance 2-{2-hydroxy-5-[(methylsulfonyl)methyl]phenyl}-2-methylpropanoic acid 2-{2-hydroxy-5-[(methylsulfonyl)oxy]phenyl}-2-methylpropanoic acid Not in list C11H14O6S CC(C)(c1cc(ccc1O)OS(C)(=O)=O)C(=O)O InChI=1/C11H14O6S/c1-11(2,10(13)14)8-6-7(4-5-9(8)12)17-18(3,15)16/h4-6,12H,1-3H3,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is a metabolite of the substance 2-{2-hydroxy-5-[(methylsulfonyl)methyl]phenyl}-2-methylpropanoic acid 2-{2-hydroxy-5-[(methylsulfonyl)oxy]phenyl}-2-methylpropanoic acid Not in list C11H14O6S CC(C)(c1cc(ccc1O)OS(C)(=O)=O)C(=O)O InChI=1/C11H14O6S/c1-11(2,10(13)14)8-6-7(4-5-9(8)12)17-18(3,15)16/h4-6,12H,1-3H3,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is a metabolite of the substance 2-{2-hydroxy-5-[(methylsulfonyl)methyl]phenyl}-2-methylpropanoic acid 2-{2-hydroxy-5-[(methylsulfonyl)oxy]phenyl}-2-methylpropanoic acid Not in list C11H14O6S CC(C)(c1cc(ccc1O)OS(C)(=O)=O)C(=O)O InChI=1/C11H14O6S/c1-11(2,10(13)14)8-6-7(4-5-9(8)12)17-18(3,15)16/h4-6,12H,1-3H3,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is a metabolite of the substance 2-{2-hydroxy-5-[(methylsulfonyl)methyl]phenyl}-2-methylpropanoic acid 2-{2-hydroxy-5-[(methylsulfonyl)oxy]phenyl}-2-methylpropanoic acid Not in list C11H14O6S CC(C)(c1cc(ccc1O)OS(C)(=O)=O)C(=O)O InChI=1/C11H14O6S/c1-11(2,10(13)14)8-6-7(4-5-9(8)12)17-18(3,15)16/h4-6,12H,1-3H3,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is a metabolite of the substance 2-{2-hydroxy-5-[(methylsulfonyl)methyl]phenyl}-2-methylpropanoic acid 2-{2-hydroxy-5-[(methylsulfonyl)oxy]phenyl}-2-methylpropanoic acid Not in list C11H14O6S CC(C)(c1cc(ccc1O)OS(C)(=O)=O)C(=O)O InChI=1/C11H14O6S/c1-11(2,10(13)14)8-6-7(4-5-9(8)12)17-18(3,15)16/h4-6,12H,1-3H3,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is a metabolite of the substance 2-{2-hydroxy-5-[(methylsulfonyl)methyl]phenyl}-2-methylpropanoic acid 2-{2-hydroxy-5-[(methylsulfonyl)oxy]phenyl}-2-methylpropanoic acid Not in list C11H14O6S CC(C)(c1cc(ccc1O)OS(C)(=O)=O)C(=O)O InChI=1/C11H14O6S/c1-11(2,10(13)14)8-6-7(4-5-9(8)12)17-18(3,15)16/h4-6,12H,1-3H3,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is a metabolite of the substance 2-{2-hydroxy-5-[(methylsulfonyl)methyl]phenyl}-2-methylpropanoic acid 2-{2-hydroxy-5-[(methylsulfonyl)oxy]phenyl}-2-methylpropanoic acid Not in list C11H14O6S CC(C)(c1cc(ccc1O)OS(C)(=O)=O)C(=O)O InChI=1/C11H14O6S/c1-11(2,10(13)14)8-6-7(4-5-9(8)12)17-18(3,15)16/h4-6,12H,1-3H3,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes without Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is a metabolite of the substance 2-{2-hydroxy-5-[(methylsulfonyl)methyl]phenyl}-2-methylpropanoic acid 2-{2-hydroxy-5-[(methylsulfonyl)oxy]phenyl}-2-methylpropanoic acid Not in list C11H14O6S CC(C)(c1cc(ccc1O)OS(C)(=O)=O)C(=O)O InChI=1/C11H14O6S/c1-11(2,10(13)14)8-6-7(4-5-9(8)12)17-18(3,15)16/h4-6,12H,1-3H3,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is a metabolite of the substance 2-{2-hydroxy-5-[(methylsulfonyl)methyl]phenyl}-2-methylpropanoic acid 2-{2-hydroxy-5-[(methylsulfonyl)oxy]phenyl}-2-methylpropanoic acid Not in list C11H14O6S CC(C)(c1cc(ccc1O)OS(C)(=O)=O)C(=O)O InChI=1/C11H14O6S/c1-11(2,10(13)14)8-6-7(4-5-9(8)12)17-18(3,15)16/h4-6,12H,1-3H3,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is a metabolite of the substance sodium 2-{2-hydroxy-5-[(methylsulfonyl)methyl]phenyl}-2-methylpropanoate sodium 2-{2-hydroxy-5-[(methylsulfonyl)oxy]phenyl}-2-methylpropanoate Not in list C11H13NaO6S [Na+].CC(C)(c1cc(ccc1O)OS(C)(=O)=O)C([O-])=O InChI=1/C11H14O6S.Na/c1-11(2,10(13)14)8-6-7(4-5-9(8)12)17-18(3,15)16;/h4-6,12H,1-3H3,(H,13,14);/q;+1/p-1 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is a metabolite of the substance sodium 2-{2-hydroxy-5-[(methylsulfonyl)methyl]phenyl}-2-methylpropanoate sodium 2-{2-hydroxy-5-[(methylsulfonyl)oxy]phenyl}-2-methylpropanoate Not in list C11H13NaO6S [Na+].CC(C)(c1cc(ccc1O)OS(C)(=O)=O)C([O-])=O InChI=1/C11H14O6S.Na/c1-11(2,10(13)14)8-6-7(4-5-9(8)12)17-18(3,15)16;/h4-6,12H,1-3H3,(H,13,14);/q;+1/p-1 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is a metabolite of the substance sodium 2-{2-hydroxy-5-[(methylsulfonyl)methyl]phenyl}-2-methylpropanoate sodium 2-{2-hydroxy-5-[(methylsulfonyl)oxy]phenyl}-2-methylpropanoate Not in list C11H13NaO6S [Na+].CC(C)(c1cc(ccc1O)OS(C)(=O)=O)C([O-])=O InChI=1/C11H14O6S.Na/c1-11(2,10(13)14)8-6-7(4-5-9(8)12)17-18(3,15)16;/h4-6,12H,1-3H3,(H,13,14);/q;+1/p-1 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is a metabolite of the substance sodium 2-{2-hydroxy-5-[(methylsulfonyl)methyl]phenyl}-2-methylpropanoate sodium 2-{2-hydroxy-5-[(methylsulfonyl)oxy]phenyl}-2-methylpropanoate Not in list C11H13NaO6S [Na+].CC(C)(c1cc(ccc1O)OS(C)(=O)=O)C([O-])=O InChI=1/C11H14O6S.Na/c1-11(2,10(13)14)8-6-7(4-5-9(8)12)17-18(3,15)16;/h4-6,12H,1-3H3,(H,13,14);/q;+1/p-1 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is identical to the substance Chlorpyrifos 220-864-4 2921-88-2 O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate Chlorpyrifos C9H11Cl3NO3PS S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is identical to the substance Chlorpyrifos 220-864-4 2921-88-2 O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate Chlorpyrifos C9H11Cl3NO3PS S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is identical to the substance Chlorpyrifos 220-864-4 2921-88-2 O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate Chlorpyrifos C9H11Cl3NO3PS S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is identical to the substance Chlorpyrifos 220-864-4 2921-88-2 O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate Chlorpyrifos C9H11Cl3NO3PS S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is identical to the substance Chlorpyrifos 220-864-4 2921-88-2 O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate Chlorpyrifos C9H11Cl3NO3PS S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is identical to the substance Chlorpyrifos 220-864-4 2921-88-2 O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate Chlorpyrifos C9H11Cl3NO3PS S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is identical to the substance Chlorpyrifos 220-864-4 2921-88-2 O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate Chlorpyrifos C9H11Cl3NO3PS S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is identical to the substance Chlorpyrifos 220-864-4 2921-88-2 O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate Chlorpyrifos C9H11Cl3NO3PS S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is identical to the substance Chlorpyrifos 220-864-4 2921-88-2 O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate Chlorpyrifos C9H11Cl3NO3PS S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is identical to the substance Chlorpyrifos 220-864-4 2921-88-2 O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate Chlorpyrifos C9H11Cl3NO3PS S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is identical to the substance Chlorpyrifos 220-864-4 2921-88-2 O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate Chlorpyrifos C9H11Cl3NO3PS S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is identical to the substance Chlorpyrifos 220-864-4 2921-88-2 O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate Chlorpyrifos C9H11Cl3NO3PS S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is identical to the substance Chlorpyrifos 220-864-4 2921-88-2 O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate Chlorpyrifos C9H11Cl3NO3PS S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is identical to the substance Chlorpyrifos 220-864-4 2921-88-2 O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate Chlorpyrifos C9H11Cl3NO3PS S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is identical to the substance Chlorpyrifos 220-864-4 2921-88-2 O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate Chlorpyrifos C9H11Cl3NO3PS S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is identical to the substance Chlorpyrifos 220-864-4 2921-88-2 O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate Chlorpyrifos C9H11Cl3NO3PS S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is identical to the substance Chlorpyrifos 220-864-4 2921-88-2 O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate Chlorpyrifos C9H11Cl3NO3PS S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is identical to the substance Chlorpyrifos 220-864-4 2921-88-2 O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate Chlorpyrifos C9H11Cl3NO3PS S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is identical to the substance Chlorpyrifos 220-864-4 2921-88-2 O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate Chlorpyrifos C9H11Cl3NO3PS S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is identical to the substance Chlorpyrifos 220-864-4 2921-88-2 O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate Chlorpyrifos C9H11Cl3NO3PS S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is identical to the substance Chlorpyrifos 220-864-4 2921-88-2 O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate Chlorpyrifos C9H11Cl3NO3PS S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is identical to the substance Chlorpyrifos 220-864-4 2921-88-2 O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate Chlorpyrifos C9H11Cl3NO3PS S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is identical to the substance Chlorpyrifos 220-864-4 2921-88-2 O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate Chlorpyrifos C9H11Cl3NO3PS S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is identical to the substance Chlorpyrifos 220-864-4 2921-88-2 O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate Chlorpyrifos C9H11Cl3NO3PS S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is identical to the substance Chlorpyrifos 220-864-4 2921-88-2 O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate Chlorpyrifos C9H11Cl3NO3PS S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported no data without Negative RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is identical to the substance Chlorpyrifos 220-864-4 2921-88-2 O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate Chlorpyrifos C9H11Cl3NO3PS S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable Rat (as animal) Not reported No data oral: unspecified no data not applicable Negative no evidence RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is identical to the substance Chlorpyrifos 220-864-4 2921-88-2 O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate Chlorpyrifos C9H11Cl3NO3PS S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported no data with Negative RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is identical to the substance Chlorpyrifos 220-864-4 2921-88-2 O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate Chlorpyrifos C9H11Cl3NO3PS S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) Not reported Not reported no data no data Negative RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is identical to the substance Chlorpyrifos 220-864-4 2921-88-2 O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate Chlorpyrifos C9H11Cl3NO3PS S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is identical to the substance Chlorpyrifos 220-864-4 2921-88-2 O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate Chlorpyrifos C9H11Cl3NO3PS S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is identical to the substance Chlorpyrifos 220-864-4 2921-88-2 O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate Chlorpyrifos C9H11Cl3NO3PS S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is identical to the substance Chlorpyrifos 220-864-4 2921-88-2 O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate Chlorpyrifos C9H11Cl3NO3PS S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is identical to the substance Chlorpyrifos 220-864-4 2921-88-2 O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate Chlorpyrifos C9H11Cl3NO3PS S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle without Negative RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is identical to the substance Chlorpyrifos 220-864-4 2921-88-2 O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate Chlorpyrifos C9H11Cl3NO3PS S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is identical to the substance Chlorpyrifos 220-864-4 2921-88-2 O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate Chlorpyrifos C9H11Cl3NO3PS S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is identical to the substance Chlorpyrifos 220-864-4 2921-88-2 O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate Chlorpyrifos C9H11Cl3NO3PS S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle with Negative RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is identical to the substance Chlorpyrifos 220-864-4 2921-88-2 O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate Chlorpyrifos C9H11Cl3NO3PS S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is identical to the substance Chlorpyrifos 220-864-4 2921-88-2 O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate Chlorpyrifos C9H11Cl3NO3PS S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is identical to the substance Chlorpyrifos 220-864-4 2921-88-2 O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate Chlorpyrifos C9H11Cl3NO3PS S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is identical to the substance Chlorpyrifos 220-864-4 2921-88-2 O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate Chlorpyrifos C9H11Cl3NO3PS S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is identical to the substance Chlorpyrifos 220-864-4 2921-88-2 O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate Chlorpyrifos C9H11Cl3NO3PS S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Rat (as animal) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is identical to the substance Chlorpyrifos 220-864-4 2921-88-2 O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate Chlorpyrifos C9H11Cl3NO3PS S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Rat (as animal) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is identical to the substance Chlorpyrifos 220-864-4 2921-88-2 O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate Chlorpyrifos C9H11Cl3NO3PS S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is identical to the substance Chlorpyrifos 220-864-4 2921-88-2 O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate Chlorpyrifos C9H11Cl3NO3PS S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is identical to the substance Chlorpyrifos 220-864-4 2921-88-2 O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate Chlorpyrifos C9H11Cl3NO3PS S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable House mouse (as animal) spleen cells Not reported yes without Positive RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is identical to the substance Chlorpyrifos 220-864-4 2921-88-2 O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate Chlorpyrifos C9H11Cl3NO3PS S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3 organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is identical to the substance Chlorpyrifos 220-864-4 2921-88-2 O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate Chlorpyrifos C9H11Cl3NO3PS S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3 organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported no data no data Negative RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is identical to the substance Chlorpyrifos 220-864-4 2921-88-2 O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate Chlorpyrifos C9H11Cl3NO3PS S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3 organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported no data no data Negative RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is identical to the substance Chlorpyrifos 220-864-4 2921-88-2 O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate Chlorpyrifos C9H11Cl3NO3PS S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3 organic compound Other Other DNA damage and/or repair SOS/umu test in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) K12 Not reported no data without Negative RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is identical to the substance Chlorpyrifos 220-864-4 2921-88-2 O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate Chlorpyrifos C9H11Cl3NO3PS S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3 organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is identical to the substance Chlorpyrifos 220-864-4 2921-88-2 O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate Chlorpyrifos C9H11Cl3NO3PS S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3 organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is identical to the substance Chlorpyrifos 220-864-4 2921-88-2 O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate Chlorpyrifos C9H11Cl3NO3PS S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3 organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) Yes Acceptable House mouse (as animal) spleen cells Not reported yes without Positive RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is identical to the substance Chlorpyrifos 220-864-4 2921-88-2 O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate Chlorpyrifos C9H11Cl3NO3PS S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3 organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Positive RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is identical to the substance Chlorpyrifos 220-864-4 2921-88-2 O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate Chlorpyrifos C9H11Cl3NO3PS S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3 organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Positive RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is identical to the substance Chlorpyrifos 220-864-4 2921-88-2 O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate Chlorpyrifos C9H11Cl3NO3PS S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) ICR 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is identical to the substance Chlorpyrifos 220-864-4 2921-88-2 O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate Chlorpyrifos C9H11Cl3NO3PS S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) ICR 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is identical to the substance Chlorpyrifos 220-864-4 2921-88-2 O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate Chlorpyrifos C9H11Cl3NO3PS S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) ICR 10 Male/Female oral: gavage 72.0000000000 h no not applicable Negative no evidence RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is identical to the substance Chlorpyrifos 220-864-4 2921-88-2 O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate Chlorpyrifos C9H11Cl3NO3PS S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) ICR 10 Male/Female oral: gavage 48.0000000000 h no not applicable Negative no evidence RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is identical to the substance Chlorpyrifos 220-864-4 2921-88-2 O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate Chlorpyrifos C9H11Cl3NO3PS S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) ICR 10 Male/Female oral: gavage 24.0000000000 h no not applicable Negative no evidence RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is identical to the substance Chlorpyrifos 220-864-4 2921-88-2 O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate Chlorpyrifos C9H11Cl3NO3PS S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Swiss Male/Female Not reported 30.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is identical to the substance Chlorpyrifos 220-864-4 2921-88-2 O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate Chlorpyrifos C9H11Cl3NO3PS S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Swiss Male/Female Not reported 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is identical to the substance Chlorpyrifos 220-864-4 2921-88-2 O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate Chlorpyrifos C9H11Cl3NO3PS S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Swiss Male/Female Not reported 18.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is a metabolite of the substance 3,5,6-Trichloro-2-pyridinol 229-405-2 6515-38-4 3,5,6-trichloro-1H-pyridin-2-one Not in list C5H2Cl3NO C1=C(C(=O)NC(=C1Cl)Cl)Cl InChI=1S/C5H2Cl3NO/c6-2-1-3(7)5(10)9-4(2)8/h1H,(H,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data no data Negative RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is a metabolite of the substance 3,5,6-Trichloro-2-pyridinol 229-405-2 6515-38-4 3,5,6-trichloro-1H-pyridin-2-one Not in list C5H2Cl3NO C1=C(C(=O)NC(=C1Cl)Cl)Cl InChI=1S/C5H2Cl3NO/c6-2-1-3(7)5(10)9-4(2)8/h1H,(H,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data no data Negative RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is a metabolite of the substance 3,5,6-Trichloro-2-pyridinol 229-405-2 6515-38-4 3,5,6-trichloro-1H-pyridin-2-one Not in list C5H2Cl3NO C1=C(C(=O)NC(=C1Cl)Cl)Cl InChI=1S/C5H2Cl3NO/c6-2-1-3(7)5(10)9-4(2)8/h1H,(H,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data no data Negative RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is a metabolite of the substance 3,5,6-Trichloro-2-pyridinol 229-405-2 6515-38-4 3,5,6-trichloro-1H-pyridin-2-one Not in list C5H2Cl3NO C1=C(C(=O)NC(=C1Cl)Cl)Cl InChI=1S/C5H2Cl3NO/c6-2-1-3(7)5(10)9-4(2)8/h1H,(H,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data no data Negative RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is a metabolite of the substance 3,5,6-Trichloro-2-pyridinol 229-405-2 6515-38-4 3,5,6-trichloro-1H-pyridin-2-one Not in list C5H2Cl3NO C1=C(C(=O)NC(=C1Cl)Cl)Cl InChI=1S/C5H2Cl3NO/c6-2-1-3(7)5(10)9-4(2)8/h1H,(H,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data no data Negative RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is a metabolite of the substance 3,5,6-Trichloro-2-pyridinol 229-405-2 6515-38-4 3,5,6-trichloro-1H-pyridin-2-one Not in list C5H2Cl3NO C1=C(C(=O)NC(=C1Cl)Cl)Cl InChI=1S/C5H2Cl3NO/c6-2-1-3(7)5(10)9-4(2)8/h1H,(H,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported no data with Negative RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Chlorpyrifos 220-864-4 2921-88-2 single chemical entity Component is a metabolite of the substance 3,5,6-Trichloro-2-pyridinol 229-405-2 6515-38-4 3,5,6-trichloro-1H-pyridin-2-one Not in list C5H2Cl3NO C1=C(C(=O)NC(=C1Cl)Cl)Cl InChI=1S/C5H2Cl3NO/c6-2-1-3(7)5(10)9-4(2)8/h1H,(H,9,10) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No data Acceptable Rat (as animal) hepatocytes Not reported no data no data Negative RMS: Spain Chlorpyrifos 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos 31Jan2011 2011 doi:10.2903/j.efsa.2011.1961
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) (k12)p3478 Not reported yes no data Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Salmonella typhimurium (as organism) TA1978 Not reported yes no data Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes no data Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) CM571 Not reported yes no data Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) CM611 Not reported yes no data Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) W3110 Not reported yes no data Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) WP67 Not reported yes no data Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes no data Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported no data without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Rat (as animal) hepatocytes Not reported no data without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Rat (as animal) hepatocytes Not reported no data without Inconclusive RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Human (as organism) alveolar basal epithelial cells (A549) Not reported no data with Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Human (as organism) alveolar basal epithelial cells (A549) Not reported no data without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle with Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) GY5027 Not reported no data without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) GY4015 Not reported no data with Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) GY5027 Not reported no data with Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) GY4015 Not reported no data without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle with Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle with Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is a metabolite of the substance 2,3-phenazine-diamine 211-512-0 655-86-7 phenazine-2,3-diamine Not in list C12H10N4 C1=CC=C2C(=C1)N=C3C=C(C(=CC3=N2)N)N InChI=1S/C12H10N4/c13-7-5-11-12(6-8(7)14)16-10-4-2-1-3-9(10)15-11/h1-6H,13-14H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is a metabolite of the substance 2,3-phenazine-diamine 211-512-0 655-86-7 phenazine-2,3-diamine Not in list C12H10N4 C1=CC=C2C(=C1)N=C3C=C(C(=CC3=N2)N)N InChI=1S/C12H10N4/c13-7-5-11-12(6-8(7)14)16-10-4-2-1-3-9(10)15-11/h1-6H,13-14H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is a metabolite of the substance 2,3-phenazine-diamine 211-512-0 655-86-7 phenazine-2,3-diamine Not in list C12H10N4 C1=CC=C2C(=C1)N=C3C=C(C(=CC3=N2)N)N InChI=1S/C12H10N4/c13-7-5-11-12(6-8(7)14)16-10-4-2-1-3-9(10)15-11/h1-6H,13-14H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Positive RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is a metabolite of the substance 5-hydroxy-benzimidazol-2-yl 22769-68-2 methyl N-(6-hydroxy-1H-benzimidazol-2-yl)carbamate Not in list C9H9N3O3 COC(=O)NC1=NC2=C(N1)C=C(C=C2)O InChI=1S/C9H9N3O3/c1-15-9(14)12-8-10-6-3-2-5(13)4-7(6)11-8/h2-4,13H,1H3,(H2,10,11,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is a metabolite of the substance 5-hydroxy-benzimidazol-2-yl 22769-68-2 methyl N-(6-hydroxy-1H-benzimidazol-2-yl)carbamate Not in list C9H9N3O3 COC(=O)NC1=NC2=C(N1)C=C(C=C2)O InChI=1S/C9H9N3O3/c1-15-9(14)12-8-10-6-3-2-5(13)4-7(6)11-8/h2-4,13H,1H3,(H2,10,11,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is a metabolite of the substance 2,3-phenazine-diamine 211-512-0 655-86-7 phenazine-2,3-diamine Not in list C12H10N4 C1=CC=C2C(=C1)N=C3C=C(C(=CC3=N2)N)N InChI=1S/C12H10N4/c13-7-5-11-12(6-8(7)14)16-10-4-2-1-3-9(10)15-11/h1-6H,13-14H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Positive RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is a metabolite of the substance 2,3-phenazine-diamine 211-512-0 655-86-7 phenazine-2,3-diamine Not in list C12H10N4 C1=CC=C2C(=C1)N=C3C=C(C(=CC3=N2)N)N InChI=1S/C12H10N4/c13-7-5-11-12(6-8(7)14)16-10-4-2-1-3-9(10)15-11/h1-6H,13-14H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Positive RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is a metabolite of the substance 5-hydroxy-benzimidazol-2-yl 22769-68-2 methyl N-(6-hydroxy-1H-benzimidazol-2-yl)carbamate Not in list C9H9N3O3 COC(=O)NC1=NC2=C(N1)C=C(C=C2)O InChI=1S/C9H9N3O3/c1-15-9(14)12-8-10-6-3-2-5(13)4-7(6)11-8/h2-4,13H,1H3,(H2,10,11,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is a metabolite of the substance 5-hydroxy-benzimidazol-2-yl 22769-68-2 methyl N-(6-hydroxy-1H-benzimidazol-2-yl)carbamate Not in list C9H9N3O3 COC(=O)NC1=NC2=C(N1)C=C(C=C2)O InChI=1S/C9H9N3O3/c1-15-9(14)12-8-10-6-3-2-5(13)4-7(6)11-8/h2-4,13H,1H3,(H2,10,11,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is a metabolite of the substance 5-hydroxy-benzimidazol-2-yl 22769-68-2 methyl N-(6-hydroxy-1H-benzimidazol-2-yl)carbamate Not in list C9H9N3O3 COC(=O)NC1=NC2=C(N1)C=C(C=C2)O InChI=1S/C9H9N3O3/c1-15-9(14)12-8-10-6-3-2-5(13)4-7(6)11-8/h2-4,13H,1H3,(H2,10,11,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is a metabolite of the substance 2,3-phenazine-diamine 211-512-0 655-86-7 phenazine-2,3-diamine Not in list C12H10N4 C1=CC=C2C(=C1)N=C3C=C(C(=CC3=N2)N)N InChI=1S/C12H10N4/c13-7-5-11-12(6-8(7)14)16-10-4-2-1-3-9(10)15-11/h1-6H,13-14H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Positive RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is a metabolite of the substance 5-hydroxy-benzimidazol-2-yl 22769-68-2 methyl N-(6-hydroxy-1H-benzimidazol-2-yl)carbamate Not in list C9H9N3O3 COC(=O)NC1=NC2=C(N1)C=C(C=C2)O InChI=1S/C9H9N3O3/c1-15-9(14)12-8-10-6-3-2-5(13)4-7(6)11-8/h2-4,13H,1H3,(H2,10,11,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is a metabolite of the substance 5-hydroxy-benzimidazol-2-yl 22769-68-2 methyl N-(6-hydroxy-1H-benzimidazol-2-yl)carbamate Not in list C9H9N3O3 COC(=O)NC1=NC2=C(N1)C=C(C=C2)O InChI=1S/C9H9N3O3/c1-15-9(14)12-8-10-6-3-2-5(13)4-7(6)11-8/h2-4,13H,1H3,(H2,10,11,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is a metabolite of the substance 5-hydroxy-benzimidazol-2-yl 22769-68-2 methyl N-(6-hydroxy-1H-benzimidazol-2-yl)carbamate Not in list C9H9N3O3 COC(=O)NC1=NC2=C(N1)C=C(C=C2)O InChI=1S/C9H9N3O3/c1-15-9(14)12-8-10-6-3-2-5(13)4-7(6)11-8/h2-4,13H,1H3,(H2,10,11,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Positive RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Positive RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Positive RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Positive RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Positive RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Positive RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Positive RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Inconclusive RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Positive RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Positive RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Positive RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro Equivalent or similar to OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay) Yes Acceptable Saccharomyces cerevisiae (as organism) D7 Not reported yes, concurrent vehicle with Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro Equivalent or similar to OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay) Yes Acceptable Saccharomyces cerevisiae (as organism) D7 Not reported yes, concurrent vehicle without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Positive no information RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other chromosome aberration in vitro mammalian cell micronucleus test in vitro Equivalent or similar to OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Positive RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other chromosome aberration other in vitro No guideline available Not reported Not applicable Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Positive RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other chromosome aberration in vitro mammalian cell micronucleus test in vitro Equivalent or similar to OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Positive RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other chromosome aberration other in vitro No guideline available Not reported Not applicable Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Positive RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) Yes Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) Yes Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation other in vivo No guideline available Not reported Not applicable Acceptable Drosophila melanogaster (as animal) Not reported Male/Female oral: feed no data not applicable Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other genome mutation Drosophila SLRL test in vivo Equivalent or similar to OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster) No data Acceptable Drosophila melanogaster (as animal) Oregon-R Male Not reported no data not applicable Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No data Acceptable Human (as organism) lymphocytes Not reported no data no data Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation mouse spot test in vivo Equivalent or similar to OECD Guideline 484 (Genetic Toxicology: Mouse Spot Test) No data Acceptable House mouse (as animal) Not reported Female Not reported yes not applicable Inconclusive RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Rat (as animal) Sprague-Dawley 8 Male/Female oral: unspecified 48.0000000000 h no data not applicable Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Rat (as animal) Sprague-Dawley 8 Male/Female oral: unspecified 6.0000000000 h no data not applicable Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Rat (as animal) Sprague-Dawley 8 Male/Female oral: unspecified 24.0000000000 h no data not applicable Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Hamster (as animal) Chinese 4 No data oral: unspecified 6.0000000000 h no data not applicable Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Hamster (as animal) Chinese 4 No data oral: unspecified 30.0000000000 h no data not applicable Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 72.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) BDF1 mouse 10 Male/Female oral: gavage 48.0000000000 h yes not applicable Positive direct evidence-cytotoxicity RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI Male/Female Not reported no data not applicable Positive no evidence RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI Male/Female Not reported no data not applicable Positive no evidence RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No data Acceptable House mouse (as animal) ICR No data oral: unspecified no data not applicable Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable House mouse (as animal) ICR No data Not reported no data not applicable Positive RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) ICR 6 Male oral: unspecified 24.0000000000 h yes not applicable Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable Rat (as animal) Wistar No data oral: gavage 6.0000000000 h yes not applicable Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable Rat (as animal) Wistar No data oral: unspecified 6.0000000000 h yes not applicable Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable Rat (as animal) Wistar No data oral: unspecified 24.0000000000 h yes not applicable Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable Rat (as animal) Wistar No data oral: gavage yes not applicable Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable Rat (as animal) Wistar No data oral: gavage 2.0000000000 h yes not applicable Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable Rat (as animal) Wistar No data oral: unspecified 72.0000000000 h yes not applicable Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable Rat (as animal) Wistar No data oral: gavage 4.0000000000 h yes not applicable Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) Yes Acceptable House mouse (as animal) NMRI 20 Male intraperitoneal yes not applicable Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) Yes Acceptable House mouse (as animal) NMRI 20 Male intraperitoneal yes not applicable Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) Yes Acceptable House mouse (as animal) NMRI 22 Male oral: gavage yes not applicable Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other chromosome aberration other in vitro No guideline available Not reported Not applicable Acceptable House mouse (as animal) embryo cells Not reported no data without Positive RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable House mouse (as animal) Not reported No data oral: feed no data not applicable Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) Not reported Not reported no data no data Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other chromosome aberration other in vitro No guideline available Not reported Not applicable Acceptable Human (as organism) lymphocytes Not reported yes without Positive RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is part of a group but not included in the group assessment Thiophanate-methyl 245-740-7 23564-05-8 methyl N-[[2-(methoxycarbonylcarbamothioylamino)phenyl]carbamothioyl]carbamate Thiophanate-methyl C12H14N4O4S2 COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC InChI=1S/C12H14N4O4S2/c1-19-11(17)15-9(21)13-7-5-3-4-6-8(7)14-10(22)16-12(18)20-2/h3-6H,1-2H3,(H2,13,15,17,21)(H2,14,16,18,22) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) BDF1 mouse 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Positive no evidence RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is part of a group but not included in the group assessment Thiophanate-methyl 245-740-7 23564-05-8 methyl N-[[2-(methoxycarbonylcarbamothioylamino)phenyl]carbamothioyl]carbamate Thiophanate-methyl C12H14N4O4S2 COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC InChI=1S/C12H14N4O4S2/c1-19-11(17)15-9(21)13-7-5-3-4-6-8(7)14-10(22)16-12(18)20-2/h3-6H,1-2H3,(H2,13,15,17,21)(H2,14,16,18,22) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) BDF1 mouse 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Positive no evidence RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other chromosome aberration other in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) Not reported 5 Male oral: gavage 22.0000000000 D yes not applicable Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Fenazaquin 120928-09-8 single chemical entity Component is identical to the substance Fenazaquin 120928-09-8 4-[2-(4-tert-butylphenyl)ethoxy]quinazoline Fenazaquin C20H22N2O CC(C)(C)C3=CC=C(C=C3)CCOC1=NC=NC2=C1C=CC=C2 InChI=1S/C20H22N2O/c1-20(2,3)16-10-8-15(9-11-16)12-13-23-19-17-6-4-5-7-18(17)21-14-22-19/h4-11,14H,12-13H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Greece Fenazaquin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin 04Apr2013 2013 doi:10.2903/j.efsa.2013.3166
+Fenazaquin 120928-09-8 single chemical entity Component is identical to the substance Fenazaquin 120928-09-8 4-[2-(4-tert-butylphenyl)ethoxy]quinazoline Fenazaquin C20H22N2O CC(C)(C)C3=CC=C(C=C3)CCOC1=NC=NC2=C1C=CC=C2 InChI=1S/C20H22N2O/c1-20(2,3)16-10-8-15(9-11-16)12-13-23-19-17-6-4-5-7-18(17)21-14-22-19/h4-11,14H,12-13H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Greece Fenazaquin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin 04Apr2013 2013 doi:10.2903/j.efsa.2013.3166
+Fenazaquin 120928-09-8 single chemical entity Component is identical to the substance Fenazaquin 120928-09-8 4-[2-(4-tert-butylphenyl)ethoxy]quinazoline Fenazaquin C20H22N2O CC(C)(C)C3=CC=C(C=C3)CCOC1=NC=NC2=C1C=CC=C2 InChI=1S/C20H22N2O/c1-20(2,3)16-10-8-15(9-11-16)12-13-23-19-17-6-4-5-7-18(17)21-14-22-19/h4-11,14H,12-13H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Greece Fenazaquin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin 04Apr2013 2013 doi:10.2903/j.efsa.2013.3166
+Fenazaquin 120928-09-8 single chemical entity Component is identical to the substance Fenazaquin 120928-09-8 4-[2-(4-tert-butylphenyl)ethoxy]quinazoline Fenazaquin C20H22N2O CC(C)(C)C3=CC=C(C=C3)CCOC1=NC=NC2=C1C=CC=C2 InChI=1S/C20H22N2O/c1-20(2,3)16-10-8-15(9-11-16)12-13-23-19-17-6-4-5-7-18(17)21-14-22-19/h4-11,14H,12-13H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Greece Fenazaquin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin 04Apr2013 2013 doi:10.2903/j.efsa.2013.3166
+Fenazaquin 120928-09-8 single chemical entity Component is identical to the substance Fenazaquin 120928-09-8 4-[2-(4-tert-butylphenyl)ethoxy]quinazoline Fenazaquin C20H22N2O CC(C)(C)C3=CC=C(C=C3)CCOC1=NC=NC2=C1C=CC=C2 InChI=1S/C20H22N2O/c1-20(2,3)16-10-8-15(9-11-16)12-13-23-19-17-6-4-5-7-18(17)21-14-22-19/h4-11,14H,12-13H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Greece Fenazaquin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin 04Apr2013 2013 doi:10.2903/j.efsa.2013.3166
+Fenazaquin 120928-09-8 single chemical entity Component is identical to the substance Fenazaquin 120928-09-8 4-[2-(4-tert-butylphenyl)ethoxy]quinazoline Fenazaquin C20H22N2O CC(C)(C)C3=CC=C(C=C3)CCOC1=NC=NC2=C1C=CC=C2 InChI=1S/C20H22N2O/c1-20(2,3)16-10-8-15(9-11-16)12-13-23-19-17-6-4-5-7-18(17)21-14-22-19/h4-11,14H,12-13H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Greece Fenazaquin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin 04Apr2013 2013 doi:10.2903/j.efsa.2013.3166
+Fenazaquin 120928-09-8 single chemical entity Component is identical to the substance Fenazaquin 120928-09-8 4-[2-(4-tert-butylphenyl)ethoxy]quinazoline Fenazaquin C20H22N2O CC(C)(C)C3=CC=C(C=C3)CCOC1=NC=NC2=C1C=CC=C2 InChI=1S/C20H22N2O/c1-20(2,3)16-10-8-15(9-11-16)12-13-23-19-17-6-4-5-7-18(17)21-14-22-19/h4-11,14H,12-13H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Greece Fenazaquin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin 04Apr2013 2013 doi:10.2903/j.efsa.2013.3166
+Fenazaquin 120928-09-8 single chemical entity Component is identical to the substance Fenazaquin 120928-09-8 4-[2-(4-tert-butylphenyl)ethoxy]quinazoline Fenazaquin C20H22N2O CC(C)(C)C3=CC=C(C=C3)CCOC1=NC=NC2=C1C=CC=C2 InChI=1S/C20H22N2O/c1-20(2,3)16-10-8-15(9-11-16)12-13-23-19-17-6-4-5-7-18(17)21-14-22-19/h4-11,14H,12-13H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Greece Fenazaquin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin 04Apr2013 2013 doi:10.2903/j.efsa.2013.3166
+Fenazaquin 120928-09-8 single chemical entity Component is identical to the substance Fenazaquin 120928-09-8 4-[2-(4-tert-butylphenyl)ethoxy]quinazoline Fenazaquin C20H22N2O CC(C)(C)C3=CC=C(C=C3)CCOC1=NC=NC2=C1C=CC=C2 InChI=1S/C20H22N2O/c1-20(2,3)16-10-8-15(9-11-16)12-13-23-19-17-6-4-5-7-18(17)21-14-22-19/h4-11,14H,12-13H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Greece Fenazaquin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin 04Apr2013 2013 doi:10.2903/j.efsa.2013.3166
+Fenazaquin 120928-09-8 single chemical entity Component is identical to the substance Fenazaquin 120928-09-8 4-[2-(4-tert-butylphenyl)ethoxy]quinazoline Fenazaquin C20H22N2O CC(C)(C)C3=CC=C(C=C3)CCOC1=NC=NC2=C1C=CC=C2 InChI=1S/C20H22N2O/c1-20(2,3)16-10-8-15(9-11-16)12-13-23-19-17-6-4-5-7-18(17)21-14-22-19/h4-11,14H,12-13H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Greece Fenazaquin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin 04Apr2013 2013 doi:10.2903/j.efsa.2013.3166
+Fenazaquin 120928-09-8 single chemical entity Component is identical to the substance Fenazaquin 120928-09-8 4-[2-(4-tert-butylphenyl)ethoxy]quinazoline Fenazaquin C20H22N2O CC(C)(C)C3=CC=C(C=C3)CCOC1=NC=NC2=C1C=CC=C2 InChI=1S/C20H22N2O/c1-20(2,3)16-10-8-15(9-11-16)12-13-23-19-17-6-4-5-7-18(17)21-14-22-19/h4-11,14H,12-13H2,1-3H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Positive no information RMS: Greece Fenazaquin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin 04Apr2013 2013 doi:10.2903/j.efsa.2013.3166
+Fenazaquin 120928-09-8 single chemical entity Component is identical to the substance Fenazaquin 120928-09-8 4-[2-(4-tert-butylphenyl)ethoxy]quinazoline Fenazaquin C20H22N2O CC(C)(C)C3=CC=C(C=C3)CCOC1=NC=NC2=C1C=CC=C2 InChI=1S/C20H22N2O/c1-20(2,3)16-10-8-15(9-11-16)12-13-23-19-17-6-4-5-7-18(17)21-14-22-19/h4-11,14H,12-13H2,1-3H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Positive no information RMS: Greece Fenazaquin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin 04Apr2013 2013 doi:10.2903/j.efsa.2013.3166
+Fenazaquin 120928-09-8 single chemical entity Component is identical to the substance Fenazaquin 120928-09-8 4-[2-(4-tert-butylphenyl)ethoxy]quinazoline Fenazaquin C20H22N2O CC(C)(C)C3=CC=C(C=C3)CCOC1=NC=NC2=C1C=CC=C2 InChI=1S/C20H22N2O/c1-20(2,3)16-10-8-15(9-11-16)12-13-23-19-17-6-4-5-7-18(17)21-14-22-19/h4-11,14H,12-13H2,1-3H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Positive RMS: Greece Fenazaquin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin 04Apr2013 2013 doi:10.2903/j.efsa.2013.3166
+Fenazaquin 120928-09-8 single chemical entity Component is identical to the substance Fenazaquin 120928-09-8 4-[2-(4-tert-butylphenyl)ethoxy]quinazoline Fenazaquin C20H22N2O CC(C)(C)C3=CC=C(C=C3)CCOC1=NC=NC2=C1C=CC=C2 InChI=1S/C20H22N2O/c1-20(2,3)16-10-8-15(9-11-16)12-13-23-19-17-6-4-5-7-18(17)21-14-22-19/h4-11,14H,12-13H2,1-3H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Positive RMS: Greece Fenazaquin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin 04Apr2013 2013 doi:10.2903/j.efsa.2013.3166
+Fenazaquin 120928-09-8 single chemical entity Component is identical to the substance Fenazaquin 120928-09-8 4-[2-(4-tert-butylphenyl)ethoxy]quinazoline Fenazaquin C20H22N2O CC(C)(C)C3=CC=C(C=C3)CCOC1=NC=NC2=C1C=CC=C2 InChI=1S/C20H22N2O/c1-20(2,3)16-10-8-15(9-11-16)12-13-23-19-17-6-4-5-7-18(17)21-14-22-19/h4-11,14H,12-13H2,1-3H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Inconclusive RMS: Greece Fenazaquin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin 04Apr2013 2013 doi:10.2903/j.efsa.2013.3166
+Fenazaquin 120928-09-8 single chemical entity Component is identical to the substance Fenazaquin 120928-09-8 4-[2-(4-tert-butylphenyl)ethoxy]quinazoline Fenazaquin C20H22N2O CC(C)(C)C3=CC=C(C=C3)CCOC1=NC=NC2=C1C=CC=C2 InChI=1S/C20H22N2O/c1-20(2,3)16-10-8-15(9-11-16)12-13-23-19-17-6-4-5-7-18(17)21-14-22-19/h4-11,14H,12-13H2,1-3H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Positive RMS: Greece Fenazaquin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin 04Apr2013 2013 doi:10.2903/j.efsa.2013.3166
+Fenazaquin 120928-09-8 single chemical entity Component is identical to the substance Fenazaquin 120928-09-8 4-[2-(4-tert-butylphenyl)ethoxy]quinazoline Fenazaquin C20H22N2O CC(C)(C)C3=CC=C(C=C3)CCOC1=NC=NC2=C1C=CC=C2 InChI=1S/C20H22N2O/c1-20(2,3)16-10-8-15(9-11-16)12-13-23-19-17-6-4-5-7-18(17)21-14-22-19/h4-11,14H,12-13H2,1-3H3 organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Greece Fenazaquin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin 04Apr2013 2013 doi:10.2903/j.efsa.2013.3166
+Fenazaquin 120928-09-8 single chemical entity Component is identical to the substance Fenazaquin 120928-09-8 4-[2-(4-tert-butylphenyl)ethoxy]quinazoline Fenazaquin C20H22N2O CC(C)(C)C3=CC=C(C=C3)CCOC1=NC=NC2=C1C=CC=C2 InChI=1S/C20H22N2O/c1-20(2,3)16-10-8-15(9-11-16)12-13-23-19-17-6-4-5-7-18(17)21-14-22-19/h4-11,14H,12-13H2,1-3H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) ICR Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Greece Fenazaquin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin 04Apr2013 2013 doi:10.2903/j.efsa.2013.3166
+Fenazaquin 120928-09-8 single chemical entity Component is identical to the substance Fenazaquin 120928-09-8 4-[2-(4-tert-butylphenyl)ethoxy]quinazoline Fenazaquin C20H22N2O CC(C)(C)C3=CC=C(C=C3)CCOC1=NC=NC2=C1C=CC=C2 InChI=1S/C20H22N2O/c1-20(2,3)16-10-8-15(9-11-16)12-13-23-19-17-6-4-5-7-18(17)21-14-22-19/h4-11,14H,12-13H2,1-3H3 organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Sprague-Dawley Male oral: gavage 14.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Greece Fenazaquin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin 04Apr2013 2013 doi:10.2903/j.efsa.2013.3166
+Fenazaquin 120928-09-8 single chemical entity Component is identical to the substance Fenazaquin 120928-09-8 4-[2-(4-tert-butylphenyl)ethoxy]quinazoline Fenazaquin C20H22N2O CC(C)(C)C3=CC=C(C=C3)CCOC1=NC=NC2=C1C=CC=C2 InChI=1S/C20H22N2O/c1-20(2,3)16-10-8-15(9-11-16)12-13-23-19-17-6-4-5-7-18(17)21-14-22-19/h4-11,14H,12-13H2,1-3H3 organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Sprague-Dawley Male oral: gavage 2.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Greece Fenazaquin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin 04Apr2013 2013 doi:10.2903/j.efsa.2013.3166
+Fenazaquin 120928-09-8 single chemical entity Component is identical to the substance Fenazaquin 120928-09-8 4-[2-(4-tert-butylphenyl)ethoxy]quinazoline Fenazaquin C20H22N2O CC(C)(C)C3=CC=C(C=C3)CCOC1=NC=NC2=C1C=CC=C2 InChI=1S/C20H22N2O/c1-20(2,3)16-10-8-15(9-11-16)12-13-23-19-17-6-4-5-7-18(17)21-14-22-19/h4-11,14H,12-13H2,1-3H3 organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) CD-1 3 Male oral: gavage 25.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Greece Fenazaquin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin 04Apr2013 2013 doi:10.2903/j.efsa.2013.3166
+Fenazaquin 120928-09-8 single chemical entity Component is a metabolite of the substance 2-(4-tert-butylphenyl)ethanol 34386-42-0 1-(4-tert-butylphenyl)ethanol Not in list C12H18O CC(C1=CC=C(C=C1)C(C)(C)C)O InChI=1S/C12H18O/c1-9(13)10-5-7-11(8-6-10)12(2,3)4/h5-9,13H,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Greece Fenazaquin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin 04Apr2013 2013 doi:10.2903/j.efsa.2013.3166
+Fenazaquin 120928-09-8 single chemical entity Component is a metabolite of the substance 2-(4-tert-butylphenyl)ethanol 34386-42-0 1-(4-tert-butylphenyl)ethanol Not in list C12H18O CC(C1=CC=C(C=C1)C(C)(C)C)O InChI=1S/C12H18O/c1-9(13)10-5-7-11(8-6-10)12(2,3)4/h5-9,13H,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Greece Fenazaquin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin 04Apr2013 2013 doi:10.2903/j.efsa.2013.3166
+Fenazaquin 120928-09-8 single chemical entity Component is a metabolite of the substance 2-(4-tert-butylphenyl)ethanol 34386-42-0 1-(4-tert-butylphenyl)ethanol Not in list C12H18O CC(C1=CC=C(C=C1)C(C)(C)C)O InChI=1S/C12H18O/c1-9(13)10-5-7-11(8-6-10)12(2,3)4/h5-9,13H,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Greece Fenazaquin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin 04Apr2013 2013 doi:10.2903/j.efsa.2013.3166
+Fenazaquin 120928-09-8 single chemical entity Component is a metabolite of the substance 2-(4-tert-butylphenyl)ethanol 34386-42-0 1-(4-tert-butylphenyl)ethanol Not in list C12H18O CC(C1=CC=C(C=C1)C(C)(C)C)O InChI=1S/C12H18O/c1-9(13)10-5-7-11(8-6-10)12(2,3)4/h5-9,13H,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Greece Fenazaquin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin 04Apr2013 2013 doi:10.2903/j.efsa.2013.3166
+Fenazaquin 120928-09-8 single chemical entity Component is a metabolite of the substance 2-(4-tert-butylphenyl)ethanol 34386-42-0 1-(4-tert-butylphenyl)ethanol Not in list C12H18O CC(C1=CC=C(C=C1)C(C)(C)C)O InChI=1S/C12H18O/c1-9(13)10-5-7-11(8-6-10)12(2,3)4/h5-9,13H,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Greece Fenazaquin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin 04Apr2013 2013 doi:10.2903/j.efsa.2013.3166
+Fenazaquin 120928-09-8 single chemical entity Component is a metabolite of the substance 2-(4-tert-butylphenyl)ethanol 34386-42-0 1-(4-tert-butylphenyl)ethanol Not in list C12H18O CC(C1=CC=C(C=C1)C(C)(C)C)O InChI=1S/C12H18O/c1-9(13)10-5-7-11(8-6-10)12(2,3)4/h5-9,13H,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Greece Fenazaquin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin 04Apr2013 2013 doi:10.2903/j.efsa.2013.3166
+Fenazaquin 120928-09-8 single chemical entity Component is a metabolite of the substance 2-(4-tert-butylphenyl)ethanol 34386-42-0 1-(4-tert-butylphenyl)ethanol Not in list C12H18O CC(C1=CC=C(C=C1)C(C)(C)C)O InChI=1S/C12H18O/c1-9(13)10-5-7-11(8-6-10)12(2,3)4/h5-9,13H,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Greece Fenazaquin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin 04Apr2013 2013 doi:10.2903/j.efsa.2013.3166
+Fenazaquin 120928-09-8 single chemical entity Component is a metabolite of the substance 2-(4-tert-butylphenyl)ethanol 34386-42-0 1-(4-tert-butylphenyl)ethanol Not in list C12H18O CC(C1=CC=C(C=C1)C(C)(C)C)O InChI=1S/C12H18O/c1-9(13)10-5-7-11(8-6-10)12(2,3)4/h5-9,13H,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Greece Fenazaquin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin 04Apr2013 2013 doi:10.2903/j.efsa.2013.3166
+Fenazaquin 120928-09-8 single chemical entity Component is a metabolite of the substance 2-(4-tert-butylphenyl)ethanol 34386-42-0 1-(4-tert-butylphenyl)ethanol Not in list C12H18O CC(C1=CC=C(C=C1)C(C)(C)C)O InChI=1S/C12H18O/c1-9(13)10-5-7-11(8-6-10)12(2,3)4/h5-9,13H,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data no data Negative RMS: Greece Fenazaquin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin 04Apr2013 2013 doi:10.2903/j.efsa.2013.3166
+Fenazaquin 120928-09-8 single chemical entity Component is a metabolite of the substance 2-(4-tert-butylphenyl)ethanol 34386-42-0 1-(4-tert-butylphenyl)ethanol Not in list C12H18O CC(C1=CC=C(C=C1)C(C)(C)C)O InChI=1S/C12H18O/c1-9(13)10-5-7-11(8-6-10)12(2,3)4/h5-9,13H,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data no data Negative RMS: Greece Fenazaquin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin 04Apr2013 2013 doi:10.2903/j.efsa.2013.3166
+Fenazaquin 120928-09-8 single chemical entity Component is a metabolite of the substance 2-(4-tert-butylphenyl)ethanol 34386-42-0 1-(4-tert-butylphenyl)ethanol Not in list C12H18O CC(C1=CC=C(C=C1)C(C)(C)C)O InChI=1S/C12H18O/c1-9(13)10-5-7-11(8-6-10)12(2,3)4/h5-9,13H,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data no data Negative RMS: Greece Fenazaquin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin 04Apr2013 2013 doi:10.2903/j.efsa.2013.3166
+Fenazaquin 120928-09-8 single chemical entity Component is a metabolite of the substance 2-(4-tert-butylphenyl)ethanol 34386-42-0 1-(4-tert-butylphenyl)ethanol Not in list C12H18O CC(C1=CC=C(C=C1)C(C)(C)C)O InChI=1S/C12H18O/c1-9(13)10-5-7-11(8-6-10)12(2,3)4/h5-9,13H,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data no data Positive RMS: Greece Fenazaquin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin 04Apr2013 2013 doi:10.2903/j.efsa.2013.3166
+Fenazaquin 120928-09-8 single chemical entity Component is a metabolite of the substance quinazolin-4-ol 207-735-8 491-36-1 1H-quinazolin-4-one Not in list C8H6N2O C1=CC=C2C(=C1)C(=O)N=CN2 InChI=1S/C8H6N2O/c11-8-6-3-1-2-4-7(6)9-5-10-8/h1-5H,(H,9,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Greece Fenazaquin (Addendum to DAR) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin 04Apr2013 2013 doi:10.2903/j.efsa.2013.3166
+Fenazaquin 120928-09-8 single chemical entity Component is a metabolite of the substance quinazolin-4-ol 207-735-8 491-36-1 1H-quinazolin-4-one Not in list C8H6N2O C1=CC=C2C(=C1)C(=O)N=CN2 InChI=1S/C8H6N2O/c11-8-6-3-1-2-4-7(6)9-5-10-8/h1-5H,(H,9,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Greece Fenazaquin (Addendum to DAR) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin 04Apr2013 2013 doi:10.2903/j.efsa.2013.3166
+Fenazaquin 120928-09-8 single chemical entity Component is a metabolite of the substance quinazolin-4-ol 207-735-8 491-36-1 1H-quinazolin-4-one Not in list C8H6N2O C1=CC=C2C(=C1)C(=O)N=CN2 InChI=1S/C8H6N2O/c11-8-6-3-1-2-4-7(6)9-5-10-8/h1-5H,(H,9,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Greece Fenazaquin (Addendum to DAR) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin 04Apr2013 2013 doi:10.2903/j.efsa.2013.3166
+Fenazaquin 120928-09-8 single chemical entity Component is a metabolite of the substance quinazolin-4-ol 207-735-8 491-36-1 1H-quinazolin-4-one Not in list C8H6N2O C1=CC=C2C(=C1)C(=O)N=CN2 InChI=1S/C8H6N2O/c11-8-6-3-1-2-4-7(6)9-5-10-8/h1-5H,(H,9,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Greece Fenazaquin (Addendum to DAR) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin 04Apr2013 2013 doi:10.2903/j.efsa.2013.3166
+Fenazaquin 120928-09-8 single chemical entity Component is a metabolite of the substance quinazolin-4-ol 207-735-8 491-36-1 1H-quinazolin-4-one Not in list C8H6N2O C1=CC=C2C(=C1)C(=O)N=CN2 InChI=1S/C8H6N2O/c11-8-6-3-1-2-4-7(6)9-5-10-8/h1-5H,(H,9,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Greece Fenazaquin (Addendum to DAR) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin 04Apr2013 2013 doi:10.2903/j.efsa.2013.3166
+Fenazaquin 120928-09-8 single chemical entity Component is a metabolite of the substance quinazolin-4-ol 207-735-8 491-36-1 1H-quinazolin-4-one Not in list C8H6N2O C1=CC=C2C(=C1)C(=O)N=CN2 InChI=1S/C8H6N2O/c11-8-6-3-1-2-4-7(6)9-5-10-8/h1-5H,(H,9,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Greece Fenazaquin (Addendum to DAR) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin 04Apr2013 2013 doi:10.2903/j.efsa.2013.3166
+Fenazaquin 120928-09-8 single chemical entity Component is a metabolite of the substance quinazolin-4-ol 207-735-8 491-36-1 1H-quinazolin-4-one Not in list C8H6N2O C1=CC=C2C(=C1)C(=O)N=CN2 InChI=1S/C8H6N2O/c11-8-6-3-1-2-4-7(6)9-5-10-8/h1-5H,(H,9,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Greece Fenazaquin (Addendum to DAR) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin 04Apr2013 2013 doi:10.2903/j.efsa.2013.3166
+Fenazaquin 120928-09-8 single chemical entity Component is a metabolite of the substance quinazolin-4-ol 207-735-8 491-36-1 1H-quinazolin-4-one Not in list C8H6N2O C1=CC=C2C(=C1)C(=O)N=CN2 InChI=1S/C8H6N2O/c11-8-6-3-1-2-4-7(6)9-5-10-8/h1-5H,(H,9,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Greece Fenazaquin (Addendum to DAR) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin 04Apr2013 2013 doi:10.2903/j.efsa.2013.3166
+Fenazaquin 120928-09-8 single chemical entity Component is a metabolite of the substance quinazolin-4-ol 207-735-8 491-36-1 1H-quinazolin-4-one Not in list C8H6N2O C1=CC=C2C(=C1)C(=O)N=CN2 InChI=1S/C8H6N2O/c11-8-6-3-1-2-4-7(6)9-5-10-8/h1-5H,(H,9,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Greece Fenazaquin (Addendum to DAR) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin 04Apr2013 2013 doi:10.2903/j.efsa.2013.3166
+Fenazaquin 120928-09-8 single chemical entity Component is a metabolite of the substance quinazolin-4-ol 207-735-8 491-36-1 1H-quinazolin-4-one Not in list C8H6N2O C1=CC=C2C(=C1)C(=O)N=CN2 InChI=1S/C8H6N2O/c11-8-6-3-1-2-4-7(6)9-5-10-8/h1-5H,(H,9,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Greece Fenazaquin (Addendum to DAR) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin 04Apr2013 2013 doi:10.2903/j.efsa.2013.3166
+Fenazaquin 120928-09-8 single chemical entity Component is identical to the substance Fenazaquin 120928-09-8 4-[2-(4-tert-butylphenyl)ethoxy]quinazoline Fenazaquin C20H22N2O CC(C)(C)C3=CC=C(C=C3)CCOC1=NC=NC2=C1C=CC=C2 InChI=1S/C20H22N2O/c1-20(2,3)16-10-8-15(9-11-16)12-13-23-19-17-6-4-5-7-18(17)21-14-22-19/h4-11,14H,12-13H2,1-3H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) ICR 6 Female oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity RMS: Greece Fenazaquin (Additional report to volume 3) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin 04Apr2013 2013 doi:10.2903/j.efsa.2013.3166
+Geraniol 269-750-6 106-24-1 single chemical entity Component is identical to the substance Geraniol 269-750-6 106-24-1 (2E)-3,7-dimethylocta-2,6-dien-1-ol geraniol C10H18O CC(=CCCC(=CCO)C)C InChI=1S/C10H18O/c1-9(2)5-4-6-10(3)7-8-11/h5,7,11H,4,6,8H2,1-3H3/b10-7+ organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: The United Kingdom Geraniol 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance geraniol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2915
+Geraniol 269-750-6 106-24-1 single chemical entity Component is identical to the substance Geraniol 269-750-6 106-24-1 (2E)-3,7-dimethylocta-2,6-dien-1-ol geraniol C10H18O CC(=CCCC(=CCO)C)C InChI=1S/C10H18O/c1-9(2)5-4-6-10(3)7-8-11/h5,7,11H,4,6,8H2,1-3H3/b10-7+ organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: The United Kingdom Geraniol 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance geraniol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2915
+Geraniol 269-750-6 106-24-1 single chemical entity Component is identical to the substance Geraniol 269-750-6 106-24-1 (2E)-3,7-dimethylocta-2,6-dien-1-ol geraniol C10H18O CC(=CCCC(=CCO)C)C InChI=1S/C10H18O/c1-9(2)5-4-6-10(3)7-8-11/h5,7,11H,4,6,8H2,1-3H3/b10-7+ organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) Yes Acceptable Hamster (as animal) CHO Not reported no data without Negative RMS: The United Kingdom Geraniol 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance geraniol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2915
+Geraniol 269-750-6 106-24-1 single chemical entity Component is part of a group assessment Geranyl acetate 203-341-5 105-87-3 [(2E)-3,7-dimethylocta-2,6-dienyl] acetate Not in list C12H20O2 CC(=CCCC(=CCOC(=O)C)C)C InChI=1S/C12H20O2/c1-10(2)6-5-7-11(3)8-9-14-12(4)13/h6,8H,5,7,9H2,1-4H3/b11-8+ organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Rat (as animal) hepatocytes Not reported no data without Negative RMS: The United Kingdom Geraniol 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance geraniol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2915
+Carbaryl 200-555-0 63-25-2 single chemical entity Component is identical to the substance Carbaryl 200-555-0 63-25-2 1-naphthyl methylcarbamate Carbaryl C12H11NO2 CNC(=O)Oc1cccc2ccccc12 InChI=1/C12H11NO2/c1-13-12(14)15-11-8-4-6-9-5-2-3-7-10(9)11/h2-8H,1H3,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Spain Carbaryl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance carbaryl 13Jun2006 2006 doi:10.2903/j.efsa.2006.80r
+Carbaryl 200-555-0 63-25-2 single chemical entity Component is identical to the substance Carbaryl 200-555-0 63-25-2 1-naphthyl methylcarbamate Carbaryl C12H11NO2 CNC(=O)Oc1cccc2ccccc12 InChI=1/C12H11NO2/c1-13-12(14)15-11-8-4-6-9-5-2-3-7-10(9)11/h2-8H,1H3,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Spain Carbaryl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance carbaryl 13Jun2006 2006 doi:10.2903/j.efsa.2006.80r
+Carbaryl 200-555-0 63-25-2 single chemical entity Component is identical to the substance Carbaryl 200-555-0 63-25-2 1-naphthyl methylcarbamate Carbaryl C12H11NO2 CNC(=O)Oc1cccc2ccccc12 InChI=1/C12H11NO2/c1-13-12(14)15-11-8-4-6-9-5-2-3-7-10(9)11/h2-8H,1H3,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Spain Carbaryl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance carbaryl 13Jun2006 2006 doi:10.2903/j.efsa.2006.80r
+Carbaryl 200-555-0 63-25-2 single chemical entity Component is identical to the substance Carbaryl 200-555-0 63-25-2 1-naphthyl methylcarbamate Carbaryl C12H11NO2 CNC(=O)Oc1cccc2ccccc12 InChI=1/C12H11NO2/c1-13-12(14)15-11-8-4-6-9-5-2-3-7-10(9)11/h2-8H,1H3,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Spain Carbaryl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance carbaryl 13Jun2006 2006 doi:10.2903/j.efsa.2006.80r
+Carbaryl 200-555-0 63-25-2 single chemical entity Component is identical to the substance Carbaryl 200-555-0 63-25-2 1-naphthyl methylcarbamate Carbaryl C12H11NO2 CNC(=O)Oc1cccc2ccccc12 InChI=1/C12H11NO2/c1-13-12(14)15-11-8-4-6-9-5-2-3-7-10(9)11/h2-8H,1H3,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Spain Carbaryl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance carbaryl 13Jun2006 2006 doi:10.2903/j.efsa.2006.80r
+Carbaryl 200-555-0 63-25-2 single chemical entity Component is identical to the substance Carbaryl 200-555-0 63-25-2 1-naphthyl methylcarbamate Carbaryl C12H11NO2 CNC(=O)Oc1cccc2ccccc12 InChI=1/C12H11NO2/c1-13-12(14)15-11-8-4-6-9-5-2-3-7-10(9)11/h2-8H,1H3,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Spain Carbaryl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance carbaryl 13Jun2006 2006 doi:10.2903/j.efsa.2006.80r
+Carbaryl 200-555-0 63-25-2 single chemical entity Component is identical to the substance Carbaryl 200-555-0 63-25-2 1-naphthyl methylcarbamate Carbaryl C12H11NO2 CNC(=O)Oc1cccc2ccccc12 InChI=1/C12H11NO2/c1-13-12(14)15-11-8-4-6-9-5-2-3-7-10(9)11/h2-8H,1H3,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Spain Carbaryl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance carbaryl 13Jun2006 2006 doi:10.2903/j.efsa.2006.80r
+Carbaryl 200-555-0 63-25-2 single chemical entity Component is identical to the substance Carbaryl 200-555-0 63-25-2 1-naphthyl methylcarbamate Carbaryl C12H11NO2 CNC(=O)Oc1cccc2ccccc12 InChI=1/C12H11NO2/c1-13-12(14)15-11-8-4-6-9-5-2-3-7-10(9)11/h2-8H,1H3,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Spain Carbaryl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance carbaryl 13Jun2006 2006 doi:10.2903/j.efsa.2006.80r
+Carbaryl 200-555-0 63-25-2 single chemical entity Component is identical to the substance Carbaryl 200-555-0 63-25-2 1-naphthyl methylcarbamate Carbaryl C12H11NO2 CNC(=O)Oc1cccc2ccccc12 InChI=1/C12H11NO2/c1-13-12(14)15-11-8-4-6-9-5-2-3-7-10(9)11/h2-8H,1H3,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Spain Carbaryl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance carbaryl 13Jun2006 2006 doi:10.2903/j.efsa.2006.80r
+Carbaryl 200-555-0 63-25-2 single chemical entity Component is identical to the substance Carbaryl 200-555-0 63-25-2 1-naphthyl methylcarbamate Carbaryl C12H11NO2 CNC(=O)Oc1cccc2ccccc12 InChI=1/C12H11NO2/c1-13-12(14)15-11-8-4-6-9-5-2-3-7-10(9)11/h2-8H,1H3,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Spain Carbaryl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance carbaryl 13Jun2006 2006 doi:10.2903/j.efsa.2006.80r
+Carbaryl 200-555-0 63-25-2 single chemical entity Component is identical to the substance Carbaryl 200-555-0 63-25-2 1-naphthyl methylcarbamate Carbaryl C12H11NO2 CNC(=O)Oc1cccc2ccccc12 InChI=1/C12H11NO2/c1-13-12(14)15-11-8-4-6-9-5-2-3-7-10(9)11/h2-8H,1H3,(H,13,14) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: Spain Carbaryl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance carbaryl 13Jun2006 2006 doi:10.2903/j.efsa.2006.80r
+Carbaryl 200-555-0 63-25-2 single chemical entity Component is identical to the substance Carbaryl 200-555-0 63-25-2 1-naphthyl methylcarbamate Carbaryl C12H11NO2 CNC(=O)Oc1cccc2ccccc12 InChI=1/C12H11NO2/c1-13-12(14)15-11-8-4-6-9-5-2-3-7-10(9)11/h2-8H,1H3,(H,13,14) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes with Ambiguous RMS: Spain Carbaryl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance carbaryl 13Jun2006 2006 doi:10.2903/j.efsa.2006.80r
+Carbaryl 200-555-0 63-25-2 single chemical entity Component is identical to the substance Carbaryl 200-555-0 63-25-2 1-naphthyl methylcarbamate Carbaryl C12H11NO2 CNC(=O)Oc1cccc2ccccc12 InChI=1/C12H11NO2/c1-13-12(14)15-11-8-4-6-9-5-2-3-7-10(9)11/h2-8H,1H3,(H,13,14) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: Spain Carbaryl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance carbaryl 13Jun2006 2006 doi:10.2903/j.efsa.2006.80r
+Carbaryl 200-555-0 63-25-2 single chemical entity Component is identical to the substance Carbaryl 200-555-0 63-25-2 1-naphthyl methylcarbamate Carbaryl C12H11NO2 CNC(=O)Oc1cccc2ccccc12 InChI=1/C12H11NO2/c1-13-12(14)15-11-8-4-6-9-5-2-3-7-10(9)11/h2-8H,1H3,(H,13,14) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes with Positive RMS: Spain Carbaryl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance carbaryl 13Jun2006 2006 doi:10.2903/j.efsa.2006.80r
+Carbaryl 200-555-0 63-25-2 single chemical entity Component is identical to the substance Carbaryl 200-555-0 63-25-2 1-naphthyl methylcarbamate Carbaryl C12H11NO2 CNC(=O)Oc1cccc2ccccc12 InChI=1/C12H11NO2/c1-13-12(14)15-11-8-4-6-9-5-2-3-7-10(9)11/h2-8H,1H3,(H,13,14) organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes without Negative RMS: Spain Carbaryl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance carbaryl 13Jun2006 2006 doi:10.2903/j.efsa.2006.80r
+Carbaryl 200-555-0 63-25-2 single chemical entity Component is identical to the substance Carbaryl 200-555-0 63-25-2 1-naphthyl methylcarbamate Carbaryl C12H11NO2 CNC(=O)Oc1cccc2ccccc12 InChI=1/C12H11NO2/c1-13-12(14)15-11-8-4-6-9-5-2-3-7-10(9)11/h2-8H,1H3,(H,13,14) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 48.0000000000 h yes not applicable Negative indirect evidence-systemic toxicity RMS: Spain Carbaryl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance carbaryl 13Jun2006 2006 doi:10.2903/j.efsa.2006.80r
+Carbaryl 200-555-0 63-25-2 single chemical entity Component is identical to the substance Carbaryl 200-555-0 63-25-2 1-naphthyl methylcarbamate Carbaryl C12H11NO2 CNC(=O)Oc1cccc2ccccc12 InChI=1/C12H11NO2/c1-13-12(14)15-11-8-4-6-9-5-2-3-7-10(9)11/h2-8H,1H3,(H,13,14) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes not applicable Negative indirect evidence-systemic toxicity RMS: Spain Carbaryl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance carbaryl 13Jun2006 2006 doi:10.2903/j.efsa.2006.80r
+Carbaryl 200-555-0 63-25-2 single chemical entity Component is identical to the substance Carbaryl 200-555-0 63-25-2 1-naphthyl methylcarbamate Carbaryl C12H11NO2 CNC(=O)Oc1cccc2ccccc12 InChI=1/C12H11NO2/c1-13-12(14)15-11-8-4-6-9-5-2-3-7-10(9)11/h2-8H,1H3,(H,13,14) organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Sprague-Dawley 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Spain Carbaryl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance carbaryl 13Jun2006 2006 doi:10.2903/j.efsa.2006.80r
+Carbaryl 200-555-0 63-25-2 single chemical entity Component is identical to the substance Carbaryl 200-555-0 63-25-2 1-naphthyl methylcarbamate Carbaryl C12H11NO2 CNC(=O)Oc1cccc2ccccc12 InChI=1/C12H11NO2/c1-13-12(14)15-11-8-4-6-9-5-2-3-7-10(9)11/h2-8H,1H3,(H,13,14) organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Sprague-Dawley 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Spain Carbaryl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance carbaryl 13Jun2006 2006 doi:10.2903/j.efsa.2006.80r
+Carbaryl 200-555-0 63-25-2 single chemical entity Component is identical to the substance Carbaryl 200-555-0 63-25-2 1-naphthyl methylcarbamate Carbaryl C12H11NO2 CNC(=O)Oc1cccc2ccccc12 InChI=1/C12H11NO2/c1-13-12(14)15-11-8-4-6-9-5-2-3-7-10(9)11/h2-8H,1H3,(H,13,14) organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Sprague-Dawley 10 Male/Female oral: gavage 6.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Spain Carbaryl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance carbaryl 13Jun2006 2006 doi:10.2903/j.efsa.2006.80r
+Carbaryl 200-555-0 63-25-2 single chemical entity Component is identical to the substance Carbaryl 200-555-0 63-25-2 1-naphthyl methylcarbamate Carbaryl C12H11NO2 CNC(=O)Oc1cccc2ccccc12 InChI=1/C12H11NO2/c1-13-12(14)15-11-8-4-6-9-5-2-3-7-10(9)11/h2-8H,1H3,(H,13,14) organic compound Other Other DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) CD-1 5 Male oral: gavage yes not applicable Negative RMS: Spain Carbaryl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance carbaryl 13Jun2006 2006 doi:10.2903/j.efsa.2006.80r
+Fenpyroximate 134098-61-6 single chemical entity Component is identical to the substance Fenpyroximate 134098-61-6 Tert-butyl 4-[[(E)-(1,3-dimethyl-5-phenoxypyrazol-4-yl)methylideneamino]oxymethyl]benzoate Fenpyroximate C24H27N3O4 CC1=NN(C(=C1/C=N/OCC2=CC=C(C=C2)C(=O)OC(C)(C)C)OC3=CC=CC=C3)C InChI=1S/C24H27N3O4/c1-17-21(22(27(5)26-17)30-20-9-7-6-8-10-20)15-25-29-16-18-11-13-19(14-12-18)23(28)31-24(2,3)4/h6-15H,16H2,1-5H3/b25-15+ organic compound PubChem isomeric SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes without Negative RMS: Germany Fenpyroximate 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyroximate 13Dec2013 2013 doi:10.2903/j.efsa.2013.3493
+Fenpyroximate 134098-61-6 single chemical entity Component is identical to the substance Fenpyroximate 134098-61-6 Tert-butyl 4-[[(E)-(1,3-dimethyl-5-phenoxypyrazol-4-yl)methylideneamino]oxymethyl]benzoate Fenpyroximate C24H27N3O4 CC1=NN(C(=C1/C=N/OCC2=CC=C(C=C2)C(=O)OC(C)(C)C)OC3=CC=CC=C3)C InChI=1S/C24H27N3O4/c1-17-21(22(27(5)26-17)30-20-9-7-6-8-10-20)15-25-29-16-18-11-13-19(14-12-18)23(28)31-24(2,3)4/h6-15H,16H2,1-5H3/b25-15+ organic compound PubChem isomeric SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes without Negative RMS: Germany Fenpyroximate 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyroximate 13Dec2013 2013 doi:10.2903/j.efsa.2013.3493
+Fenpyroximate 134098-61-6 single chemical entity Component is identical to the substance Fenpyroximate 134098-61-6 Tert-butyl 4-[[(E)-(1,3-dimethyl-5-phenoxypyrazol-4-yl)methylideneamino]oxymethyl]benzoate Fenpyroximate C24H27N3O4 CC1=NN(C(=C1/C=N/OCC2=CC=C(C=C2)C(=O)OC(C)(C)C)OC3=CC=CC=C3)C InChI=1S/C24H27N3O4/c1-17-21(22(27(5)26-17)30-20-9-7-6-8-10-20)15-25-29-16-18-11-13-19(14-12-18)23(28)31-24(2,3)4/h6-15H,16H2,1-5H3/b25-15+ organic compound PubChem isomeric SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes with Negative RMS: Germany Fenpyroximate 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyroximate 13Dec2013 2013 doi:10.2903/j.efsa.2013.3493
+Fenpyroximate 134098-61-6 single chemical entity Component is identical to the substance Fenpyroximate 134098-61-6 Tert-butyl 4-[[(E)-(1,3-dimethyl-5-phenoxypyrazol-4-yl)methylideneamino]oxymethyl]benzoate Fenpyroximate C24H27N3O4 CC1=NN(C(=C1/C=N/OCC2=CC=C(C=C2)C(=O)OC(C)(C)C)OC3=CC=CC=C3)C InChI=1S/C24H27N3O4/c1-17-21(22(27(5)26-17)30-20-9-7-6-8-10-20)15-25-29-16-18-11-13-19(14-12-18)23(28)31-24(2,3)4/h6-15H,16H2,1-5H3/b25-15+ organic compound PubChem isomeric SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes with Negative RMS: Germany Fenpyroximate 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyroximate 13Dec2013 2013 doi:10.2903/j.efsa.2013.3493
+Fenpyroximate 134098-61-6 single chemical entity Component is identical to the substance Fenpyroximate 134098-61-6 Tert-butyl 4-[[(E)-(1,3-dimethyl-5-phenoxypyrazol-4-yl)methylideneamino]oxymethyl]benzoate Fenpyroximate C24H27N3O4 CC1=NN(C(=C1/C=N/OCC2=CC=C(C=C2)C(=O)OC(C)(C)C)OC3=CC=CC=C3)C InChI=1S/C24H27N3O4/c1-17-21(22(27(5)26-17)30-20-9-7-6-8-10-20)15-25-29-16-18-11-13-19(14-12-18)23(28)31-24(2,3)4/h6-15H,16H2,1-5H3/b25-15+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany Fenpyroximate 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyroximate 13Dec2013 2013 doi:10.2903/j.efsa.2013.3493
+Fenpyroximate 134098-61-6 single chemical entity Component is identical to the substance Fenpyroximate 134098-61-6 Tert-butyl 4-[[(E)-(1,3-dimethyl-5-phenoxypyrazol-4-yl)methylideneamino]oxymethyl]benzoate Fenpyroximate C24H27N3O4 CC1=NN(C(=C1/C=N/OCC2=CC=C(C=C2)C(=O)OC(C)(C)C)OC3=CC=CC=C3)C InChI=1S/C24H27N3O4/c1-17-21(22(27(5)26-17)30-20-9-7-6-8-10-20)15-25-29-16-18-11-13-19(14-12-18)23(28)31-24(2,3)4/h6-15H,16H2,1-5H3/b25-15+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany Fenpyroximate 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyroximate 13Dec2013 2013 doi:10.2903/j.efsa.2013.3493
+Fenpyroximate 134098-61-6 single chemical entity Component is identical to the substance Fenpyroximate 134098-61-6 Tert-butyl 4-[[(E)-(1,3-dimethyl-5-phenoxypyrazol-4-yl)methylideneamino]oxymethyl]benzoate Fenpyroximate C24H27N3O4 CC1=NN(C(=C1/C=N/OCC2=CC=C(C=C2)C(=O)OC(C)(C)C)OC3=CC=CC=C3)C InChI=1S/C24H27N3O4/c1-17-21(22(27(5)26-17)30-20-9-7-6-8-10-20)15-25-29-16-18-11-13-19(14-12-18)23(28)31-24(2,3)4/h6-15H,16H2,1-5H3/b25-15+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany Fenpyroximate 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyroximate 13Dec2013 2013 doi:10.2903/j.efsa.2013.3493
+Fenpyroximate 134098-61-6 single chemical entity Component is identical to the substance Fenpyroximate 134098-61-6 Tert-butyl 4-[[(E)-(1,3-dimethyl-5-phenoxypyrazol-4-yl)methylideneamino]oxymethyl]benzoate Fenpyroximate C24H27N3O4 CC1=NN(C(=C1/C=N/OCC2=CC=C(C=C2)C(=O)OC(C)(C)C)OC3=CC=CC=C3)C InChI=1S/C24H27N3O4/c1-17-21(22(27(5)26-17)30-20-9-7-6-8-10-20)15-25-29-16-18-11-13-19(14-12-18)23(28)31-24(2,3)4/h6-15H,16H2,1-5H3/b25-15+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany Fenpyroximate 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyroximate 13Dec2013 2013 doi:10.2903/j.efsa.2013.3493
+Fenpyroximate 134098-61-6 single chemical entity Component is identical to the substance Fenpyroximate 134098-61-6 Tert-butyl 4-[[(E)-(1,3-dimethyl-5-phenoxypyrazol-4-yl)methylideneamino]oxymethyl]benzoate Fenpyroximate C24H27N3O4 CC1=NN(C(=C1/C=N/OCC2=CC=C(C=C2)C(=O)OC(C)(C)C)OC3=CC=CC=C3)C InChI=1S/C24H27N3O4/c1-17-21(22(27(5)26-17)30-20-9-7-6-8-10-20)15-25-29-16-18-11-13-19(14-12-18)23(28)31-24(2,3)4/h6-15H,16H2,1-5H3/b25-15+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Germany Fenpyroximate 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyroximate 13Dec2013 2013 doi:10.2903/j.efsa.2013.3493
+Fenpyroximate 134098-61-6 single chemical entity Component is identical to the substance Fenpyroximate 134098-61-6 Tert-butyl 4-[[(E)-(1,3-dimethyl-5-phenoxypyrazol-4-yl)methylideneamino]oxymethyl]benzoate Fenpyroximate C24H27N3O4 CC1=NN(C(=C1/C=N/OCC2=CC=C(C=C2)C(=O)OC(C)(C)C)OC3=CC=CC=C3)C InChI=1S/C24H27N3O4/c1-17-21(22(27(5)26-17)30-20-9-7-6-8-10-20)15-25-29-16-18-11-13-19(14-12-18)23(28)31-24(2,3)4/h6-15H,16H2,1-5H3/b25-15+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Germany Fenpyroximate 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyroximate 13Dec2013 2013 doi:10.2903/j.efsa.2013.3493
+Fenpyroximate 134098-61-6 single chemical entity Component is identical to the substance Fenpyroximate 134098-61-6 Tert-butyl 4-[[(E)-(1,3-dimethyl-5-phenoxypyrazol-4-yl)methylideneamino]oxymethyl]benzoate Fenpyroximate C24H27N3O4 CC1=NN(C(=C1/C=N/OCC2=CC=C(C=C2)C(=O)OC(C)(C)C)OC3=CC=CC=C3)C InChI=1S/C24H27N3O4/c1-17-21(22(27(5)26-17)30-20-9-7-6-8-10-20)15-25-29-16-18-11-13-19(14-12-18)23(28)31-24(2,3)4/h6-15H,16H2,1-5H3/b25-15+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany Fenpyroximate 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyroximate 13Dec2013 2013 doi:10.2903/j.efsa.2013.3493
+Fenpyroximate 134098-61-6 single chemical entity Component is identical to the substance Fenpyroximate 134098-61-6 Tert-butyl 4-[[(E)-(1,3-dimethyl-5-phenoxypyrazol-4-yl)methylideneamino]oxymethyl]benzoate Fenpyroximate C24H27N3O4 CC1=NN(C(=C1/C=N/OCC2=CC=C(C=C2)C(=O)OC(C)(C)C)OC3=CC=CC=C3)C InChI=1S/C24H27N3O4/c1-17-21(22(27(5)26-17)30-20-9-7-6-8-10-20)15-25-29-16-18-11-13-19(14-12-18)23(28)31-24(2,3)4/h6-15H,16H2,1-5H3/b25-15+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany Fenpyroximate 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyroximate 13Dec2013 2013 doi:10.2903/j.efsa.2013.3493
+Fenpyroximate 134098-61-6 single chemical entity Component is identical to the substance Fenpyroximate 134098-61-6 Tert-butyl 4-[[(E)-(1,3-dimethyl-5-phenoxypyrazol-4-yl)methylideneamino]oxymethyl]benzoate Fenpyroximate C24H27N3O4 CC1=NN(C(=C1/C=N/OCC2=CC=C(C=C2)C(=O)OC(C)(C)C)OC3=CC=CC=C3)C InChI=1S/C24H27N3O4/c1-17-21(22(27(5)26-17)30-20-9-7-6-8-10-20)15-25-29-16-18-11-13-19(14-12-18)23(28)31-24(2,3)4/h6-15H,16H2,1-5H3/b25-15+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany Fenpyroximate 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyroximate 13Dec2013 2013 doi:10.2903/j.efsa.2013.3493
+Fenpyroximate 134098-61-6 single chemical entity Component is identical to the substance Fenpyroximate 134098-61-6 Tert-butyl 4-[[(E)-(1,3-dimethyl-5-phenoxypyrazol-4-yl)methylideneamino]oxymethyl]benzoate Fenpyroximate C24H27N3O4 CC1=NN(C(=C1/C=N/OCC2=CC=C(C=C2)C(=O)OC(C)(C)C)OC3=CC=CC=C3)C InChI=1S/C24H27N3O4/c1-17-21(22(27(5)26-17)30-20-9-7-6-8-10-20)15-25-29-16-18-11-13-19(14-12-18)23(28)31-24(2,3)4/h6-15H,16H2,1-5H3/b25-15+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany Fenpyroximate 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyroximate 13Dec2013 2013 doi:10.2903/j.efsa.2013.3493
+Fenpyroximate 134098-61-6 single chemical entity Component is identical to the substance Fenpyroximate 134098-61-6 Tert-butyl 4-[[(E)-(1,3-dimethyl-5-phenoxypyrazol-4-yl)methylideneamino]oxymethyl]benzoate Fenpyroximate C24H27N3O4 CC1=NN(C(=C1/C=N/OCC2=CC=C(C=C2)C(=O)OC(C)(C)C)OC3=CC=CC=C3)C InChI=1S/C24H27N3O4/c1-17-21(22(27(5)26-17)30-20-9-7-6-8-10-20)15-25-29-16-18-11-13-19(14-12-18)23(28)31-24(2,3)4/h6-15H,16H2,1-5H3/b25-15+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Germany Fenpyroximate 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyroximate 13Dec2013 2013 doi:10.2903/j.efsa.2013.3493
+Fenpyroximate 134098-61-6 single chemical entity Component is identical to the substance Fenpyroximate 134098-61-6 Tert-butyl 4-[[(E)-(1,3-dimethyl-5-phenoxypyrazol-4-yl)methylideneamino]oxymethyl]benzoate Fenpyroximate C24H27N3O4 CC1=NN(C(=C1/C=N/OCC2=CC=C(C=C2)C(=O)OC(C)(C)C)OC3=CC=CC=C3)C InChI=1S/C24H27N3O4/c1-17-21(22(27(5)26-17)30-20-9-7-6-8-10-20)15-25-29-16-18-11-13-19(14-12-18)23(28)31-24(2,3)4/h6-15H,16H2,1-5H3/b25-15+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Germany Fenpyroximate 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyroximate 13Dec2013 2013 doi:10.2903/j.efsa.2013.3493
+Fenpyroximate 134098-61-6 single chemical entity Component is identical to the substance Fenpyroximate 134098-61-6 Tert-butyl 4-[[(E)-(1,3-dimethyl-5-phenoxypyrazol-4-yl)methylideneamino]oxymethyl]benzoate Fenpyroximate C24H27N3O4 CC1=NN(C(=C1/C=N/OCC2=CC=C(C=C2)C(=O)OC(C)(C)C)OC3=CC=CC=C3)C InChI=1S/C24H27N3O4/c1-17-21(22(27(5)26-17)30-20-9-7-6-8-10-20)15-25-29-16-18-11-13-19(14-12-18)23(28)31-24(2,3)4/h6-15H,16H2,1-5H3/b25-15+ organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Germany Fenpyroximate 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyroximate 13Dec2013 2013 doi:10.2903/j.efsa.2013.3493
+Fenpyroximate 134098-61-6 single chemical entity Component is identical to the substance Fenpyroximate 134098-61-6 Tert-butyl 4-[[(E)-(1,3-dimethyl-5-phenoxypyrazol-4-yl)methylideneamino]oxymethyl]benzoate Fenpyroximate C24H27N3O4 CC1=NN(C(=C1/C=N/OCC2=CC=C(C=C2)C(=O)OC(C)(C)C)OC3=CC=CC=C3)C InChI=1S/C24H27N3O4/c1-17-21(22(27(5)26-17)30-20-9-7-6-8-10-20)15-25-29-16-18-11-13-19(14-12-18)23(28)31-24(2,3)4/h6-15H,16H2,1-5H3/b25-15+ organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Germany Fenpyroximate 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyroximate 13Dec2013 2013 doi:10.2903/j.efsa.2013.3493
+Fenpyroximate 134098-61-6 single chemical entity Component is identical to the substance Fenpyroximate 134098-61-6 Tert-butyl 4-[[(E)-(1,3-dimethyl-5-phenoxypyrazol-4-yl)methylideneamino]oxymethyl]benzoate Fenpyroximate C24H27N3O4 CC1=NN(C(=C1/C=N/OCC2=CC=C(C=C2)C(=O)OC(C)(C)C)OC3=CC=CC=C3)C InChI=1S/C24H27N3O4/c1-17-21(22(27(5)26-17)30-20-9-7-6-8-10-20)15-25-29-16-18-11-13-19(14-12-18)23(28)31-24(2,3)4/h6-15H,16H2,1-5H3/b25-15+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: Germany Fenpyroximate 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyroximate 13Dec2013 2013 doi:10.2903/j.efsa.2013.3493
+Fenpyroximate 134098-61-6 single chemical entity Component is identical to the substance Fenpyroximate 134098-61-6 Tert-butyl 4-[[(E)-(1,3-dimethyl-5-phenoxypyrazol-4-yl)methylideneamino]oxymethyl]benzoate Fenpyroximate C24H27N3O4 CC1=NN(C(=C1/C=N/OCC2=CC=C(C=C2)C(=O)OC(C)(C)C)OC3=CC=CC=C3)C InChI=1S/C24H27N3O4/c1-17-21(22(27(5)26-17)30-20-9-7-6-8-10-20)15-25-29-16-18-11-13-19(14-12-18)23(28)31-24(2,3)4/h6-15H,16H2,1-5H3/b25-15+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: Germany Fenpyroximate 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyroximate 13Dec2013 2013 doi:10.2903/j.efsa.2013.3493
+Fenpyroximate 134098-61-6 single chemical entity Component is identical to the substance Fenpyroximate 134098-61-6 Tert-butyl 4-[[(E)-(1,3-dimethyl-5-phenoxypyrazol-4-yl)methylideneamino]oxymethyl]benzoate Fenpyroximate C24H27N3O4 CC1=NN(C(=C1/C=N/OCC2=CC=C(C=C2)C(=O)OC(C)(C)C)OC3=CC=CC=C3)C InChI=1S/C24H27N3O4/c1-17-21(22(27(5)26-17)30-20-9-7-6-8-10-20)15-25-29-16-18-11-13-19(14-12-18)23(28)31-24(2,3)4/h6-15H,16H2,1-5H3/b25-15+ organic compound PubChem isomeric SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Germany Fenpyroximate 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyroximate 13Dec2013 2013 doi:10.2903/j.efsa.2013.3493
+Fenpyroximate 134098-61-6 single chemical entity Component is identical to the substance Fenpyroximate 134098-61-6 Tert-butyl 4-[[(E)-(1,3-dimethyl-5-phenoxypyrazol-4-yl)methylideneamino]oxymethyl]benzoate Fenpyroximate C24H27N3O4 CC1=NN(C(=C1/C=N/OCC2=CC=C(C=C2)C(=O)OC(C)(C)C)OC3=CC=CC=C3)C InChI=1S/C24H27N3O4/c1-17-21(22(27(5)26-17)30-20-9-7-6-8-10-20)15-25-29-16-18-11-13-19(14-12-18)23(28)31-24(2,3)4/h6-15H,16H2,1-5H3/b25-15+ organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: unspecified 72.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Germany Fenpyroximate 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyroximate 13Dec2013 2013 doi:10.2903/j.efsa.2013.3493
+Fenpyroximate 134098-61-6 single chemical entity Component is identical to the substance Fenpyroximate 134098-61-6 Tert-butyl 4-[[(E)-(1,3-dimethyl-5-phenoxypyrazol-4-yl)methylideneamino]oxymethyl]benzoate Fenpyroximate C24H27N3O4 CC1=NN(C(=C1/C=N/OCC2=CC=C(C=C2)C(=O)OC(C)(C)C)OC3=CC=CC=C3)C InChI=1S/C24H27N3O4/c1-17-21(22(27(5)26-17)30-20-9-7-6-8-10-20)15-25-29-16-18-11-13-19(14-12-18)23(28)31-24(2,3)4/h6-15H,16H2,1-5H3/b25-15+ organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: unspecified 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Germany Fenpyroximate 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyroximate 13Dec2013 2013 doi:10.2903/j.efsa.2013.3493
+Fenpyroximate 134098-61-6 single chemical entity Component is identical to the substance Fenpyroximate 134098-61-6 Tert-butyl 4-[[(E)-(1,3-dimethyl-5-phenoxypyrazol-4-yl)methylideneamino]oxymethyl]benzoate Fenpyroximate C24H27N3O4 CC1=NN(C(=C1/C=N/OCC2=CC=C(C=C2)C(=O)OC(C)(C)C)OC3=CC=CC=C3)C InChI=1S/C24H27N3O4/c1-17-21(22(27(5)26-17)30-20-9-7-6-8-10-20)15-25-29-16-18-11-13-19(14-12-18)23(28)31-24(2,3)4/h6-15H,16H2,1-5H3/b25-15+ organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Germany Fenpyroximate 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyroximate 13Dec2013 2013 doi:10.2903/j.efsa.2013.3493
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes, concurrent vehicle with Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes, concurrent vehicle without Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes, concurrent vehicle without Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes, concurrent vehicle with Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes without Positive RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes with Ambiguous RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Ambiguous no information RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Positive no information RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Positive RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Positive RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Inconclusive RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Inconclusive RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro According to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Positive RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Crj:CD(SD) 8 No data oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Crj:CD(SD) 8 No data oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Crj:CD(SD) 8 No data oral: gavage 6.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 16.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Fischer344 3 Male oral: unspecified 4.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 8 Male intraperitoneal 24.0000000000 h yes not applicable Positive direct evidence-cytotoxicity RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo Equivalent or similar to OECD Guideline 489 No data Acceptable House mouse (as animal) CD-1 4 Male intraperitoneal 4.0000000000 h yes not applicable Positive RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo Equivalent or similar to OECD Guideline 489 No data Acceptable House mouse (as animal) CD-1 4 Male intraperitoneal 24.0000000000 h yes not applicable Positive RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) CD-1 6 Female intraperitoneal 24.0000000000 h yes not applicable Positive RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) CD-1 6 Female intraperitoneal 24.0000000000 h yes not applicable Positive RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 8 Male intraperitoneal 6.0000000000 h yes not applicable Positive direct evidence-cytotoxicity RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo Equivalent or similar to OECD Guideline 489 No data Acceptable House mouse (as animal) CD-1 4 Male intraperitoneal 4.0000000000 h yes not applicable Positive RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo Equivalent or similar to OECD Guideline 489 No data Acceptable House mouse (as animal) CD-1 4 Male intraperitoneal 24.0000000000 h yes not applicable Positive RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) CD-1 6 Female intraperitoneal 24.0000000000 h yes not applicable Positive RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other chromosome aberration mammalian germ cell cytogenetic assay in vivo Equivalent or similar to OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test) Yes Acceptable Hamster (as animal) Chinese 10 Male oral: gavage 42.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other chromosome aberration mammalian germ cell cytogenetic assay in vivo Equivalent or similar to OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test) Yes Acceptable Hamster (as animal) Chinese 10 Male oral: gavage 66.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other chromosome aberration mammalian germ cell cytogenetic assay in vivo Equivalent or similar to OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test) Yes Acceptable Hamster (as animal) Chinese 10 Male oral: gavage 18.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other genome mutation Drosophila SLRL test in vivo Equivalent or similar to OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster) Yes Acceptable Drosophila melanogaster (as animal) Not reported 200 Male oral: feed yes, concurrent vehicle not applicable Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Salmonella typhimurium (as organism) Not reported Not reported no data without Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Escherichia coli (as organism) WP2 Not reported no data with Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Escherichia coli (as organism) WP2 Not reported no data without Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes, concurrent vehicle without Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes, concurrent vehicle with Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes, concurrent vehicle without Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes, concurrent vehicle with Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Not reported 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Not reported 10 Male/Female oral: gavage 72.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Not reported 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) Swiss No data Not reported no data not applicable Positive RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) DNA-polymerase-A-deficient Not reported no data without Positive RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) DNA-polymerase-A-deficient Not reported no data with Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) Swiss No data Not reported no data not applicable Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) DNA-polymerase-A-deficient Not reported no data with Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vitro No guideline available Not reported Not applicable Acceptable Human (as organism) Hep G2 human cell line Not reported no data without Positive RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) DNA-polymerase-A-deficient Not reported no data without Positive RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) Swiss No data Not reported no data not applicable Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) Swiss No data Not reported no data not applicable Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) Swiss No data Not reported no data not applicable Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian cell micronucleus test in vitro Equivalent or similar to OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test) No data Acceptable Human (as organism) Hep G2 human cell line Not reported no data no data Positive RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported no data with Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 472 (Genetic Toxicology: Escherichia coli, Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 Not reported no data with Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data with Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No data Acceptable Human (as organism) lymphocytes Not reported no data with Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No data Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data without Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No data Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data with Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 472 (Genetic Toxicology: Escherichia coli, Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 Not reported no data without Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No data Acceptable Human (as organism) lymphocytes Not reported no data without Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data without Positive RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No data Acceptable Rat (as animal) hepatocytes Not reported no data without Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data without Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data with Positive RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported no data with Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported no data without Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported no data without Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isocyanate 210-866-3 624-83-9 methylimino(oxo)methane Not in list C2H3NO CN=C=O InChI=1S/C2H3NO/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported no data without Positive RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isocyanate 210-866-3 624-83-9 methylimino(oxo)methane Not in list C2H3NO CN=C=O InChI=1S/C2H3NO/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI genome mutation Drosophila SLRL test in vivo Equivalent or similar to OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster) No data Acceptable Drosophila melanogaster (as animal) Not reported Male oral: feed no data not applicable Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isocyanate 210-866-3 624-83-9 methylimino(oxo)methane Not in list C2H3NO CN=C=O InChI=1S/C2H3NO/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data without Positive small colonies RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isocyanate 210-866-3 624-83-9 methylimino(oxo)methane Not in list C2H3NO CN=C=O InChI=1S/C2H3NO/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable House mouse (as animal) Not reported No data inhalation: unspecified no data not applicable Positive RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isocyanate 210-866-3 624-83-9 methylimino(oxo)methane Not in list C2H3NO CN=C=O InChI=1S/C2H3NO/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported no data with Positive RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isocyanate 210-866-3 624-83-9 methylimino(oxo)methane Not in list C2H3NO CN=C=O InChI=1S/C2H3NO/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) Not reported No data inhalation: unspecified no data not applicable Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isocyanate 210-866-3 624-83-9 methylimino(oxo)methane Not in list C2H3NO CN=C=O InChI=1S/C2H3NO/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) Not reported No data inhalation: unspecified no data not applicable Positive RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isocyanate 210-866-3 624-83-9 methylimino(oxo)methane Not in list C2H3NO CN=C=O InChI=1S/C2H3NO/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No data Acceptable Hamster (as animal) CHO Not reported no data with Positive RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isocyanate 210-866-3 624-83-9 methylimino(oxo)methane Not in list C2H3NO CN=C=O InChI=1S/C2H3NO/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI genome mutation Drosophila SLRL test in vivo Equivalent or similar to OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster) No data Acceptable Drosophila melanogaster (as animal) Not reported Male inhalation: unspecified no data not applicable Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isocyanate 210-866-3 624-83-9 methylimino(oxo)methane Not in list C2H3NO CN=C=O InChI=1S/C2H3NO/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) Not reported Not reported no data without Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isocyanate 210-866-3 624-83-9 methylimino(oxo)methane Not in list C2H3NO CN=C=O InChI=1S/C2H3NO/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) Not reported No data inhalation: unspecified no data not applicable Positive RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isocyanate 210-866-3 624-83-9 methylimino(oxo)methane Not in list C2H3NO CN=C=O InChI=1S/C2H3NO/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) Not reported Not reported no data with Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isocyanate 210-866-3 624-83-9 methylimino(oxo)methane Not in list C2H3NO CN=C=O InChI=1S/C2H3NO/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No data Acceptable Hamster (as animal) CHO Not reported no data without Positive RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isocyanate 210-866-3 624-83-9 methylimino(oxo)methane Not in list C2H3NO CN=C=O InChI=1S/C2H3NO/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI genome mutation Drosophila SLRL test in vivo Equivalent or similar to OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster) No data Acceptable Drosophila melanogaster (as animal) Not reported Male other no data not applicable Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isocyanate 210-866-3 624-83-9 methylimino(oxo)methane Not in list C2H3NO CN=C=O InChI=1S/C2H3NO/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No data Acceptable House mouse (as animal) Not reported No data inhalation: unspecified no data not applicable Positive RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isocyanate 210-866-3 624-83-9 methylimino(oxo)methane Not in list C2H3NO CN=C=O InChI=1S/C2H3NO/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Swiss 4 Male/Female intraperitoneal 6.0000000000 h no data not applicable Negative no evidence RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isocyanate 210-866-3 624-83-9 methylimino(oxo)methane Not in list C2H3NO CN=C=O InChI=1S/C2H3NO/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Swiss 4 Male/Female intraperitoneal 48.0000000000 h no data not applicable Negative no evidence RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isocyanate 210-866-3 624-83-9 methylimino(oxo)methane Not in list C2H3NO CN=C=O InChI=1S/C2H3NO/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Swiss 4 Male/Female intraperitoneal 6.0000000000 h no data not applicable Negative no evidence RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isocyanate 210-866-3 624-83-9 methylimino(oxo)methane Not in list C2H3NO CN=C=O InChI=1S/C2H3NO/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Swiss 4 Male/Female intraperitoneal 48.0000000000 h no data not applicable Negative no evidence RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isocyanate 210-866-3 624-83-9 methylimino(oxo)methane Not in list C2H3NO CN=C=O InChI=1S/C2H3NO/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) No data Acceptable Rat (as animal) Wistar 24 Male inhalation: unspecified no data not applicable Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is a metabolite of the substance Methyl isocyanate 210-866-3 624-83-9 methylimino(oxo)methane Not in list C2H3NO CN=C=O InChI=1S/C2H3NO/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) No data Acceptable House mouse (as animal) CD-1 Male inhalation: unspecified yes not applicable Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Fluazifop-P-butyl 79241-46-6 single chemical entity Component is identical to the substance Fluazifop-P-butyl 79241-46-6 Butyl (2R)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate Fluazifop-P-butyl C19H20F3NO4 CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F InChI=1S/C19H20F3NO4/c1-3-4-11-25-18(24)13(2)26-15-6-8-16(9-7-15)27-17-10-5-14(12-23-17)19(20,21)22/h5-10,12-13H,3-4,11H2,1-2H3/t13-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Fluazifop-P 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl) 08Nov2012 2012 doi:10.2903/j.efsa.2012.2945
+Fluazifop-P-butyl 79241-46-6 single chemical entity Component is identical to the substance Fluazifop-P-butyl 79241-46-6 Butyl (2R)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate Fluazifop-P-butyl C19H20F3NO4 CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F InChI=1S/C19H20F3NO4/c1-3-4-11-25-18(24)13(2)26-15-6-8-16(9-7-15)27-17-10-5-14(12-23-17)19(20,21)22/h5-10,12-13H,3-4,11H2,1-2H3/t13-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: France Fluazifop-P 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl) 08Nov2012 2012 doi:10.2903/j.efsa.2012.2945
+Fluazifop-P-butyl 79241-46-6 single chemical entity Component is identical to the substance Fluazifop-P-butyl 79241-46-6 Butyl (2R)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate Fluazifop-P-butyl C19H20F3NO4 CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F InChI=1S/C19H20F3NO4/c1-3-4-11-25-18(24)13(2)26-15-6-8-16(9-7-15)27-17-10-5-14(12-23-17)19(20,21)22/h5-10,12-13H,3-4,11H2,1-2H3/t13-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Fluazifop-P 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl) 08Nov2012 2012 doi:10.2903/j.efsa.2012.2945
+Fluazifop-P-butyl 79241-46-6 single chemical entity Component is identical to the substance Fluazifop-P-butyl 79241-46-6 Butyl (2R)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate Fluazifop-P-butyl C19H20F3NO4 CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F InChI=1S/C19H20F3NO4/c1-3-4-11-25-18(24)13(2)26-15-6-8-16(9-7-15)27-17-10-5-14(12-23-17)19(20,21)22/h5-10,12-13H,3-4,11H2,1-2H3/t13-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Fluazifop-P 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl) 08Nov2012 2012 doi:10.2903/j.efsa.2012.2945
+Fluazifop-P-butyl 79241-46-6 single chemical entity Component is identical to the substance Fluazifop-P-butyl 79241-46-6 Butyl (2R)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate Fluazifop-P-butyl C19H20F3NO4 CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F InChI=1S/C19H20F3NO4/c1-3-4-11-25-18(24)13(2)26-15-6-8-16(9-7-15)27-17-10-5-14(12-23-17)19(20,21)22/h5-10,12-13H,3-4,11H2,1-2H3/t13-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Fluazifop-P 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl) 08Nov2012 2012 doi:10.2903/j.efsa.2012.2945
+Fluazifop-P-butyl 79241-46-6 single chemical entity Component is identical to the substance Fluazifop-P-butyl 79241-46-6 Butyl (2R)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate Fluazifop-P-butyl C19H20F3NO4 CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F InChI=1S/C19H20F3NO4/c1-3-4-11-25-18(24)13(2)26-15-6-8-16(9-7-15)27-17-10-5-14(12-23-17)19(20,21)22/h5-10,12-13H,3-4,11H2,1-2H3/t13-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: France Fluazifop-P 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl) 08Nov2012 2012 doi:10.2903/j.efsa.2012.2945
+Fluazifop-P-butyl 79241-46-6 single chemical entity Component is identical to the substance Fluazifop-P-butyl 79241-46-6 Butyl (2R)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate Fluazifop-P-butyl C19H20F3NO4 CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F InChI=1S/C19H20F3NO4/c1-3-4-11-25-18(24)13(2)26-15-6-8-16(9-7-15)27-17-10-5-14(12-23-17)19(20,21)22/h5-10,12-13H,3-4,11H2,1-2H3/t13-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Fluazifop-P 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl) 08Nov2012 2012 doi:10.2903/j.efsa.2012.2945
+Fluazifop-P-butyl 79241-46-6 single chemical entity Component is identical to the substance Fluazifop-P-butyl 79241-46-6 Butyl (2R)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate Fluazifop-P-butyl C19H20F3NO4 CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F InChI=1S/C19H20F3NO4/c1-3-4-11-25-18(24)13(2)26-15-6-8-16(9-7-15)27-17-10-5-14(12-23-17)19(20,21)22/h5-10,12-13H,3-4,11H2,1-2H3/t13-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Fluazifop-P 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl) 08Nov2012 2012 doi:10.2903/j.efsa.2012.2945
+Fluazifop-P-butyl 79241-46-6 single chemical entity Component is identical to the substance Fluazifop-P-butyl 79241-46-6 Butyl (2R)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate Fluazifop-P-butyl C19H20F3NO4 CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F InChI=1S/C19H20F3NO4/c1-3-4-11-25-18(24)13(2)26-15-6-8-16(9-7-15)27-17-10-5-14(12-23-17)19(20,21)22/h5-10,12-13H,3-4,11H2,1-2H3/t13-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Fluazifop-P 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl) 08Nov2012 2012 doi:10.2903/j.efsa.2012.2945
+Fluazifop-P-butyl 79241-46-6 single chemical entity Component is identical to the substance Fluazifop-P-butyl 79241-46-6 Butyl (2R)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate Fluazifop-P-butyl C19H20F3NO4 CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F InChI=1S/C19H20F3NO4/c1-3-4-11-25-18(24)13(2)26-15-6-8-16(9-7-15)27-17-10-5-14(12-23-17)19(20,21)22/h5-10,12-13H,3-4,11H2,1-2H3/t13-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Fluazifop-P 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl) 08Nov2012 2012 doi:10.2903/j.efsa.2012.2945
+Fluazifop-P-butyl 79241-46-6 single chemical entity Component is identical to the substance Fluazifop-P-butyl 79241-46-6 Butyl (2R)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate Fluazifop-P-butyl C19H20F3NO4 CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F InChI=1S/C19H20F3NO4/c1-3-4-11-25-18(24)13(2)26-15-6-8-16(9-7-15)27-17-10-5-14(12-23-17)19(20,21)22/h5-10,12-13H,3-4,11H2,1-2H3/t13-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Fluazifop-P 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl) 08Nov2012 2012 doi:10.2903/j.efsa.2012.2945
+Fluazifop-P-butyl 79241-46-6 single chemical entity Component is identical to the substance Fluazifop-P-butyl 79241-46-6 Butyl (2R)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate Fluazifop-P-butyl C19H20F3NO4 CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F InChI=1S/C19H20F3NO4/c1-3-4-11-25-18(24)13(2)26-15-6-8-16(9-7-15)27-17-10-5-14(12-23-17)19(20,21)22/h5-10,12-13H,3-4,11H2,1-2H3/t13-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle without Negative RMS: France Fluazifop-P 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl) 08Nov2012 2012 doi:10.2903/j.efsa.2012.2945
+Fluazifop-P-butyl 79241-46-6 single chemical entity Component is identical to the substance Fluazifop-P-butyl 79241-46-6 Butyl (2R)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate Fluazifop-P-butyl C19H20F3NO4 CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F InChI=1S/C19H20F3NO4/c1-3-4-11-25-18(24)13(2)26-15-6-8-16(9-7-15)27-17-10-5-14(12-23-17)19(20,21)22/h5-10,12-13H,3-4,11H2,1-2H3/t13-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Fluazifop-P 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl) 08Nov2012 2012 doi:10.2903/j.efsa.2012.2945
+Fluazifop-P-butyl 79241-46-6 single chemical entity Component is identical to the substance Fluazifop-P-butyl 79241-46-6 Butyl (2R)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate Fluazifop-P-butyl C19H20F3NO4 CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F InChI=1S/C19H20F3NO4/c1-3-4-11-25-18(24)13(2)26-15-6-8-16(9-7-15)27-17-10-5-14(12-23-17)19(20,21)22/h5-10,12-13H,3-4,11H2,1-2H3/t13-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Fluazifop-P 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl) 08Nov2012 2012 doi:10.2903/j.efsa.2012.2945
+Fluazifop-P-butyl 79241-46-6 single chemical entity Component is identical to the substance Fluazifop-P-butyl 79241-46-6 Butyl (2R)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate Fluazifop-P-butyl C19H20F3NO4 CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F InChI=1S/C19H20F3NO4/c1-3-4-11-25-18(24)13(2)26-15-6-8-16(9-7-15)27-17-10-5-14(12-23-17)19(20,21)22/h5-10,12-13H,3-4,11H2,1-2H3/t13-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Fluazifop-P 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl) 08Nov2012 2012 doi:10.2903/j.efsa.2012.2945
+Fluazifop-P-butyl 79241-46-6 single chemical entity Component is identical to the substance Fluazifop-P-butyl 79241-46-6 Butyl (2R)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate Fluazifop-P-butyl C19H20F3NO4 CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F InChI=1S/C19H20F3NO4/c1-3-4-11-25-18(24)13(2)26-15-6-8-16(9-7-15)27-17-10-5-14(12-23-17)19(20,21)22/h5-10,12-13H,3-4,11H2,1-2H3/t13-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle with Negative RMS: France Fluazifop-P 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl) 08Nov2012 2012 doi:10.2903/j.efsa.2012.2945
+Fluazifop-P-butyl 79241-46-6 single chemical entity Component is identical to the substance Fluazifop-P-butyl 79241-46-6 Butyl (2R)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate Fluazifop-P-butyl C19H20F3NO4 CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F InChI=1S/C19H20F3NO4/c1-3-4-11-25-18(24)13(2)26-15-6-8-16(9-7-15)27-17-10-5-14(12-23-17)19(20,21)22/h5-10,12-13H,3-4,11H2,1-2H3/t13-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 pKM 101 E. coli Not reported yes, concurrent vehicle with Negative RMS: France Fluazifop-P 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl) 08Nov2012 2012 doi:10.2903/j.efsa.2012.2945
+Fluazifop-P-butyl 79241-46-6 single chemical entity Component is identical to the substance Fluazifop-P-butyl 79241-46-6 Butyl (2R)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate Fluazifop-P-butyl C19H20F3NO4 CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F InChI=1S/C19H20F3NO4/c1-3-4-11-25-18(24)13(2)26-15-6-8-16(9-7-15)27-17-10-5-14(12-23-17)19(20,21)22/h5-10,12-13H,3-4,11H2,1-2H3/t13-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Fluazifop-P 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl) 08Nov2012 2012 doi:10.2903/j.efsa.2012.2945
+Fluazifop-P-butyl 79241-46-6 single chemical entity Component is identical to the substance Fluazifop-P-butyl 79241-46-6 Butyl (2R)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate Fluazifop-P-butyl C19H20F3NO4 CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F InChI=1S/C19H20F3NO4/c1-3-4-11-25-18(24)13(2)26-15-6-8-16(9-7-15)27-17-10-5-14(12-23-17)19(20,21)22/h5-10,12-13H,3-4,11H2,1-2H3/t13-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Fluazifop-P 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl) 08Nov2012 2012 doi:10.2903/j.efsa.2012.2945
+Fluazifop-P-butyl 79241-46-6 single chemical entity Component is identical to the substance Fluazifop-P-butyl 79241-46-6 Butyl (2R)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate Fluazifop-P-butyl C19H20F3NO4 CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F InChI=1S/C19H20F3NO4/c1-3-4-11-25-18(24)13(2)26-15-6-8-16(9-7-15)27-17-10-5-14(12-23-17)19(20,21)22/h5-10,12-13H,3-4,11H2,1-2H3/t13-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Fluazifop-P 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl) 08Nov2012 2012 doi:10.2903/j.efsa.2012.2945
+Fluazifop-P-butyl 79241-46-6 single chemical entity Component is identical to the substance Fluazifop-P-butyl 79241-46-6 Butyl (2R)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate Fluazifop-P-butyl C19H20F3NO4 CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F InChI=1S/C19H20F3NO4/c1-3-4-11-25-18(24)13(2)26-15-6-8-16(9-7-15)27-17-10-5-14(12-23-17)19(20,21)22/h5-10,12-13H,3-4,11H2,1-2H3/t13-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 pKM 101 E. coli Not reported yes, concurrent vehicle without Negative RMS: France Fluazifop-P 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl) 08Nov2012 2012 doi:10.2903/j.efsa.2012.2945
+Fluazifop-P-butyl 79241-46-6 single chemical entity Component is identical to the substance Fluazifop-P-butyl 79241-46-6 Butyl (2R)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate Fluazifop-P-butyl C19H20F3NO4 CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F InChI=1S/C19H20F3NO4/c1-3-4-11-25-18(24)13(2)26-15-6-8-16(9-7-15)27-17-10-5-14(12-23-17)19(20,21)22/h5-10,12-13H,3-4,11H2,1-2H3/t13-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Fluazifop-P 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl) 08Nov2012 2012 doi:10.2903/j.efsa.2012.2945
+Fluazifop-P-butyl 79241-46-6 single chemical entity Component is identical to the substance Fluazifop-P-butyl 79241-46-6 Butyl (2R)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate Fluazifop-P-butyl C19H20F3NO4 CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F InChI=1S/C19H20F3NO4/c1-3-4-11-25-18(24)13(2)26-15-6-8-16(9-7-15)27-17-10-5-14(12-23-17)19(20,21)22/h5-10,12-13H,3-4,11H2,1-2H3/t13-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: France Fluazifop-P 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl) 08Nov2012 2012 doi:10.2903/j.efsa.2012.2945
+Fluazifop-P-butyl 79241-46-6 single chemical entity Component is identical to the substance Fluazifop-P-butyl 79241-46-6 Butyl (2R)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate Fluazifop-P-butyl C19H20F3NO4 CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F InChI=1S/C19H20F3NO4/c1-3-4-11-25-18(24)13(2)26-15-6-8-16(9-7-15)27-17-10-5-14(12-23-17)19(20,21)22/h5-10,12-13H,3-4,11H2,1-2H3/t13-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: France Fluazifop-P 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl) 08Nov2012 2012 doi:10.2903/j.efsa.2012.2945
+Fluazifop-P-butyl 79241-46-6 single chemical entity Component is identical to the substance Fluazifop-P-butyl 79241-46-6 Butyl (2R)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate Fluazifop-P-butyl C19H20F3NO4 CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F InChI=1S/C19H20F3NO4/c1-3-4-11-25-18(24)13(2)26-15-6-8-16(9-7-15)27-17-10-5-14(12-23-17)19(20,21)22/h5-10,12-13H,3-4,11H2,1-2H3/t13-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: France Fluazifop-P 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl) 08Nov2012 2012 doi:10.2903/j.efsa.2012.2945
+Fluazifop-P-butyl 79241-46-6 single chemical entity Component is identical to the substance Fluazifop-P-butyl 79241-46-6 Butyl (2R)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate Fluazifop-P-butyl C19H20F3NO4 CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F InChI=1S/C19H20F3NO4/c1-3-4-11-25-18(24)13(2)26-15-6-8-16(9-7-15)27-17-10-5-14(12-23-17)19(20,21)22/h5-10,12-13H,3-4,11H2,1-2H3/t13-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: France Fluazifop-P 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl) 08Nov2012 2012 doi:10.2903/j.efsa.2012.2945
+Fluazifop-P-butyl 79241-46-6 single chemical entity Component is identical to the substance Fluazifop-P-butyl 79241-46-6 Butyl (2R)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate Fluazifop-P-butyl C19H20F3NO4 CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F InChI=1S/C19H20F3NO4/c1-3-4-11-25-18(24)13(2)26-15-6-8-16(9-7-15)27-17-10-5-14(12-23-17)19(20,21)22/h5-10,12-13H,3-4,11H2,1-2H3/t13-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Not reported 10 Male/Female intraperitoneal 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: France Fluazifop-P 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl) 08Nov2012 2012 doi:10.2903/j.efsa.2012.2945
+Fluazifop-P-butyl 79241-46-6 single chemical entity Component is identical to the substance Fluazifop-P-butyl 79241-46-6 Butyl (2R)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate Fluazifop-P-butyl C19H20F3NO4 CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F InChI=1S/C19H20F3NO4/c1-3-4-11-25-18(24)13(2)26-15-6-8-16(9-7-15)27-17-10-5-14(12-23-17)19(20,21)22/h5-10,12-13H,3-4,11H2,1-2H3/t13-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Not reported 10 Male/Female intraperitoneal 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: France Fluazifop-P 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl) 08Nov2012 2012 doi:10.2903/j.efsa.2012.2945
+Fluazifop-P-butyl 79241-46-6 single chemical entity Component is identical to the substance Fluazifop-P-butyl 79241-46-6 Butyl (2R)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate Fluazifop-P-butyl C19H20F3NO4 CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F InChI=1S/C19H20F3NO4/c1-3-4-11-25-18(24)13(2)26-15-6-8-16(9-7-15)27-17-10-5-14(12-23-17)19(20,21)22/h5-10,12-13H,3-4,11H2,1-2H3/t13-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Not reported 10 Male/Female intraperitoneal 72.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: France Fluazifop-P 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl) 08Nov2012 2012 doi:10.2903/j.efsa.2012.2945
+Fluazifop-P-butyl 79241-46-6 single chemical entity Component is identical to the substance Fluazifop-P-butyl 79241-46-6 Butyl (2R)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate Fluazifop-P-butyl C19H20F3NO4 CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F InChI=1S/C19H20F3NO4/c1-3-4-11-25-18(24)13(2)26-15-6-8-16(9-7-15)27-17-10-5-14(12-23-17)19(20,21)22/h5-10,12-13H,3-4,11H2,1-2H3/t13-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Not reported 10 Male/Female intraperitoneal 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: France Fluazifop-P 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl) 08Nov2012 2012 doi:10.2903/j.efsa.2012.2945
+Fluazifop-P-butyl 79241-46-6 single chemical entity Component is identical to the substance Fluazifop-P-butyl 79241-46-6 Butyl (2R)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate Fluazifop-P-butyl C19H20F3NO4 CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F InChI=1S/C19H20F3NO4/c1-3-4-11-25-18(24)13(2)26-15-6-8-16(9-7-15)27-17-10-5-14(12-23-17)19(20,21)22/h5-10,12-13H,3-4,11H2,1-2H3/t13-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Not reported 10 Male/Female intraperitoneal 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: France Fluazifop-P 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl) 08Nov2012 2012 doi:10.2903/j.efsa.2012.2945
+Fluazifop-P-butyl 79241-46-6 single chemical entity Component is identical to the substance Fluazifop-P-butyl 79241-46-6 Butyl (2R)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate Fluazifop-P-butyl C19H20F3NO4 CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F InChI=1S/C19H20F3NO4/c1-3-4-11-25-18(24)13(2)26-15-6-8-16(9-7-15)27-17-10-5-14(12-23-17)19(20,21)22/h5-10,12-13H,3-4,11H2,1-2H3/t13-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Not reported 10 Male/Female intraperitoneal 72.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: France Fluazifop-P 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl) 08Nov2012 2012 doi:10.2903/j.efsa.2012.2945
+Fluazifop-P-butyl 79241-46-6 single chemical entity Component is a metabolite of the substance 5-(Trifluoromethyl)-2(1H)-pyridinone 33252-63-0 5-(Trifluoromethyl)-1H-pyridin-2-one Not in list C6H4F3NO C1=CC(=O)NC=C1C(F)(F)F InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: France Fluazifop-P 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl) 08Nov2012 2012 doi:10.2903/j.efsa.2012.2945
+Fluazifop-P-butyl 79241-46-6 single chemical entity Component is a metabolite of the substance 5-(Trifluoromethyl)-2(1H)-pyridinone 33252-63-0 5-(Trifluoromethyl)-1H-pyridin-2-one Not in list C6H4F3NO C1=CC(=O)NC=C1C(F)(F)F InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Fluazifop-P 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl) 08Nov2012 2012 doi:10.2903/j.efsa.2012.2945
+Fluazifop-P-butyl 79241-46-6 single chemical entity Component is a metabolite of the substance 5-(Trifluoromethyl)-2(1H)-pyridinone 33252-63-0 5-(Trifluoromethyl)-1H-pyridin-2-one Not in list C6H4F3NO C1=CC(=O)NC=C1C(F)(F)F InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Positive RMS: France Fluazifop-P 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl) 08Nov2012 2012 doi:10.2903/j.efsa.2012.2945
+Fluazifop-P-butyl 79241-46-6 single chemical entity Component is a metabolite of the substance 5-(Trifluoromethyl)-2(1H)-pyridinone 33252-63-0 5-(Trifluoromethyl)-1H-pyridin-2-one Not in list C6H4F3NO C1=CC(=O)NC=C1C(F)(F)F InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Positive RMS: France Fluazifop-P 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl) 08Nov2012 2012 doi:10.2903/j.efsa.2012.2945
+Fluazifop-P-butyl 79241-46-6 single chemical entity Component is a metabolite of the substance 5-(Trifluoromethyl)-2(1H)-pyridinone 33252-63-0 5-(Trifluoromethyl)-1H-pyridin-2-one Not in list C6H4F3NO C1=CC(=O)NC=C1C(F)(F)F InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Fluazifop-P 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl) 08Nov2012 2012 doi:10.2903/j.efsa.2012.2945
+Fluazifop-P-butyl 79241-46-6 single chemical entity Component is a metabolite of the substance 5-(Trifluoromethyl)-2(1H)-pyridinone 33252-63-0 5-(Trifluoromethyl)-1H-pyridin-2-one Not in list C6H4F3NO C1=CC(=O)NC=C1C(F)(F)F InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Fluazifop-P 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl) 08Nov2012 2012 doi:10.2903/j.efsa.2012.2945
+Fluazifop-P-butyl 79241-46-6 single chemical entity Component is a metabolite of the substance 5-(Trifluoromethyl)-2(1H)-pyridinone 33252-63-0 5-(Trifluoromethyl)-1H-pyridin-2-one Not in list C6H4F3NO C1=CC(=O)NC=C1C(F)(F)F InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Fluazifop-P 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl) 08Nov2012 2012 doi:10.2903/j.efsa.2012.2945
+Fluazifop-P-butyl 79241-46-6 single chemical entity Component is a metabolite of the substance 5-(Trifluoromethyl)-2(1H)-pyridinone 33252-63-0 5-(Trifluoromethyl)-1H-pyridin-2-one Not in list C6H4F3NO C1=CC(=O)NC=C1C(F)(F)F InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: France Fluazifop-P 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl) 08Nov2012 2012 doi:10.2903/j.efsa.2012.2945
+Fluazifop-P-butyl 79241-46-6 single chemical entity Component is a metabolite of the substance 5-(Trifluoromethyl)-2(1H)-pyridinone 33252-63-0 5-(Trifluoromethyl)-1H-pyridin-2-one Not in list C6H4F3NO C1=CC(=O)NC=C1C(F)(F)F InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Positive RMS: France Fluazifop-P 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl) 08Nov2012 2012 doi:10.2903/j.efsa.2012.2945
+Fluazifop-P-butyl 79241-46-6 single chemical entity Component is a metabolite of the substance 5-(Trifluoromethyl)-2(1H)-pyridinone 33252-63-0 5-(Trifluoromethyl)-1H-pyridin-2-one Not in list C6H4F3NO C1=CC(=O)NC=C1C(F)(F)F InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Positive RMS: France Fluazifop-P 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl) 08Nov2012 2012 doi:10.2903/j.efsa.2012.2945
+Fluazifop-P-butyl 79241-46-6 single chemical entity Component is a metabolite of the substance 5-(Trifluoromethyl)-2(1H)-pyridinone 33252-63-0 5-(Trifluoromethyl)-1H-pyridin-2-one Not in list C6H4F3NO C1=CC(=O)NC=C1C(F)(F)F InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) C57BL 10 Male/Female oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity RMS: France Fluazifop-P 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl) 08Nov2012 2012 doi:10.2903/j.efsa.2012.2945
+Fluazifop-P-butyl 79241-46-6 single chemical entity Component is a metabolite of the substance 5-(Trifluoromethyl)-2(1H)-pyridinone 33252-63-0 5-(Trifluoromethyl)-1H-pyridin-2-one Not in list C6H4F3NO C1=CC(=O)NC=C1C(F)(F)F InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) C57BL 10 Male/Female oral: unspecified 72.0000000000 h yes, concurrent vehicle not applicable Ambiguous direct evidence-cytotoxicity RMS: France Fluazifop-P 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl) 08Nov2012 2012 doi:10.2903/j.efsa.2012.2945
+Fluazifop-P-butyl 79241-46-6 single chemical entity Component is a metabolite of the substance 5-(Trifluoromethyl)-2(1H)-pyridinone 33252-63-0 5-(Trifluoromethyl)-1H-pyridin-2-one Not in list C6H4F3NO C1=CC(=O)NC=C1C(F)(F)F InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) C57BL 10 Male/Female oral: unspecified 48.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity RMS: France Fluazifop-P 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl) 08Nov2012 2012 doi:10.2903/j.efsa.2012.2945
+Fluazifop-P-butyl 79241-46-6 single chemical entity Component is a metabolite of the substance 5-(Trifluoromethyl)-2(1H)-pyridinone 33252-63-0 5-(Trifluoromethyl)-1H-pyridin-2-one Not in list C6H4F3NO C1=CC(=O)NC=C1C(F)(F)F InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo Equivalent or similar to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) Yes Acceptable Rat (as animal) Wistar Male oral: unspecified 16.0000000000 h yes, concurrent vehicle not applicable Negative RMS: France Fluazifop-P 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl) 08Nov2012 2012 doi:10.2903/j.efsa.2012.2945
+Fluazifop-P-butyl 79241-46-6 single chemical entity Component is a metabolite of the substance 5-(Trifluoromethyl)-2(1H)-pyridinone 33252-63-0 5-(Trifluoromethyl)-1H-pyridin-2-one Not in list C6H4F3NO C1=CC(=O)NC=C1C(F)(F)F InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo Equivalent or similar to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) Yes Acceptable Rat (as animal) Wistar Male oral: unspecified 2.0000000000 h yes, concurrent vehicle not applicable Negative RMS: France Fluazifop-P 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl) 08Nov2012 2012 doi:10.2903/j.efsa.2012.2945
+Fluazifop-P-butyl 79241-46-6 single chemical entity Component is a metabolite of the substance 5-(Trifluoromethyl)-2(1H)-pyridinone 33252-63-0 5-(Trifluoromethyl)-1H-pyridin-2-one Not in list C6H4F3NO C1=CC(=O)NC=C1C(F)(F)F InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: France Fluazifop-P (Addendum to the Additional Report of Volume 3 B6 – B7) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl) 08Nov2012 2012 doi:10.2903/j.efsa.2012.2945
+Fluazifop-P-butyl 79241-46-6 single chemical entity Component is a metabolite of the substance 5-(Trifluoromethyl)-2(1H)-pyridinone 33252-63-0 5-(Trifluoromethyl)-1H-pyridin-2-one Not in list C6H4F3NO C1=CC(=O)NC=C1C(F)(F)F InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: France Fluazifop-P (Addendum to the Additional Report of Volume 3 B6 – B7) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl) 08Nov2012 2012 doi:10.2903/j.efsa.2012.2945
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation yeast cytogenetic assay in vitro Equivalent or similar to OECD Guideline 480 (Genetic Toxicology: Saccharomyces cerevisiae, Gene Mutation Assay) Yes Acceptable Saccharomyces cerevisiae (as organism) D4 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation yeast cytogenetic assay in vitro Equivalent or similar to OECD Guideline 480 (Genetic Toxicology: Saccharomyces cerevisiae, Gene Mutation Assay) Yes Acceptable Saccharomyces cerevisiae (as organism) D4 Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) LT2 S. typhimurium Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Aspergillus nidulans (as organism) Not reported Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA92 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA92 Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Positive RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Positive RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Positive RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Ambiguous RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Ambiguous RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Ambiguous RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Ambiguous RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 472 (Genetic Toxicology: Escherichia coli, Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 472 (Genetic Toxicology: Escherichia coli, Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation yeast cytogenetic assay in vitro Equivalent or similar to OECD Guideline 480 (Genetic Toxicology: Saccharomyces cerevisiae, Gene Mutation Assay) Yes Acceptable Saccharomyces cerevisiae (as organism) XV 185-14C S. cerevisiae Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation yeast cytogenetic assay in vitro Equivalent or similar to OECD Guideline 480 (Genetic Toxicology: Saccharomyces cerevisiae, Gene Mutation Assay) Yes Acceptable Saccharomyces cerevisiae (as organism) XV 185-14C S. cerevisiae Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) CHY832 E. coli Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) CHY832 E. coli Not reported no data without Positive RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) embryo cells Not reported no data without Positive RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Hamster (as animal) embryo cells Not reported no data without Positive RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data without Negative no information RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data with Negative no information RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation other in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) NMRI No data Not reported no data not applicable Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation other in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) Swiss No data intraperitoneal no data not applicable Positive RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration other in vitro No guideline available Not reported Not applicable Acceptable Aspergillus nidulans (as organism) Strain P Aspergillus nidulans Not reported no data without Positive RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration other in vitro No guideline available Not reported Not applicable Acceptable Aspergillus nidulans (as organism) Strain P Aspergillus nidulans Not reported no data without Positive RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration other in vitro No guideline available Not reported Not applicable Acceptable Aspergillus nidulans (as organism) Not reported Not reported no data without Positive RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) Yes Acceptable Hamster (as animal) CHO Not reported no data with Positive RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) Yes Acceptable Hamster (as animal) CHO Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported no data with Positive RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported no data with Positive RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) WP2 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) WP100 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) DNA-polymerase-A-proficient Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) (k12)p3478 Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) W3110 Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) W3110 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) (k12)p3478 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) CM871 Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) CM871 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) WP2 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) WP67 Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) WP67 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) WP2 Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro Equivalent or similar to OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay) Yes Acceptable Saccharomyces cerevisiae (as organism) Strain T2 S. cerevisiae Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro Equivalent or similar to OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay) Yes Acceptable Saccharomyces cerevisiae (as organism) Strain T1 S. cerevisiae Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro Equivalent or similar to OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay) Yes Acceptable Saccharomyces cerevisiae (as organism) Strain T1 S. cerevisiae Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro Equivalent or similar to OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay) Yes Acceptable Saccharomyces cerevisiae (as organism) Strain T2 S. cerevisiae Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Saccharomyces cerevisiae (as organism) Not reported no data without Positive RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Saccharomyces cerevisiae (as organism) Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Human (as organism) HeLa cells Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Human (as organism) HeLa cells Not reported no data with Positive RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) 58-161 E.coli Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) GY4015 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) GY5027 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation yeast cytogenetic assay in vitro No guideline available Not reported Not applicable Acceptable Saccharomyces cerevisiae (as organism) Strain T2 S. cerevisiae Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation yeast cytogenetic assay in vitro No guideline available Not reported Not applicable Acceptable Saccharomyces cerevisiae (as organism) Strain T1 S. cerevisiae Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation yeast cytogenetic assay in vitro No guideline available Not reported Not applicable Acceptable Saccharomyces cerevisiae (as organism) Strain T2 S. cerevisiae Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation yeast cytogenetic assay in vitro No guideline available Not reported Not applicable Acceptable Saccharomyces cerevisiae (as organism) Strain T1 S. cerevisiae Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation yeast cytogenetic assay in vitro No guideline available Not reported Not applicable Acceptable Saccharomyces cerevisiae (as organism) D7 Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation yeast cytogenetic assay in vitro No guideline available Not reported Not applicable Acceptable Saccharomyces cerevisiae (as organism) D7 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Saccharomyces cerevisiae (as organism) Strain JD1 S. cerevisiae Not reported no data without Positive RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Saccharomyces cerevisiae (as organism) Strain JD1 S. cerevisiae Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair in vitro mammalian cell transformation assay in vitro No guideline available Not reported Not applicable Acceptable House mouse (as animal) 3T3 Not reported no data without Ambiguous RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair in vitro mammalian cell transformation assay in vitro No guideline available Not reported Not applicable Acceptable Hamster (as animal) kidney cells Not reported no data with Positive RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair in vitro mammalian cell transformation assay in vitro No guideline available Not reported Not applicable Acceptable Hamster (as animal) kidney cells Not reported no data with Positive RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair in vitro mammalian cell transformation assay in vitro No guideline available Not reported Not applicable Acceptable Hamster (as animal) kidney cells Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair in vitro mammalian cell transformation assay in vitro No guideline available Not reported Not applicable Acceptable Hamster (as animal) kidney cells Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair in vitro mammalian cell transformation assay in vitro No guideline available Not reported Not applicable Acceptable Hamster (as animal) embryo cells Not reported no data with Positive RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair in vitro mammalian cell transformation assay in vitro No guideline available Not reported Not applicable Acceptable Rat (as animal) embryo cells Not reported no data without Positive RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair in vitro mammalian cell transformation assay in vitro No guideline available Not reported Not applicable Acceptable Hamster (as animal) embryo cells Not reported no data without Positive RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair in vitro mammalian cell transformation assay in vitro No guideline available Not reported Not applicable Acceptable Hamster (as animal) embryo cells Not reported no data without Positive RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair in vitro mammalian cell transformation assay in vitro No guideline available Not reported Not applicable Acceptable House mouse (as animal) embryo cells Not reported no data without Positive RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair in vitro mammalian cell transformation assay in vitro No guideline available Not reported Not applicable Acceptable House mouse (as animal) embryo cells Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation other in vivo No guideline available Not reported Not applicable Acceptable Drosophila melanogaster (as animal) Not reported Female oral: feed no data not applicable Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI genome mutation Drosophila SLRL test in vivo Equivalent or similar to OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster) No data Acceptable Drosophila melanogaster (as animal) Not reported Male oral: feed no data not applicable Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI genome mutation Drosophila SLRL test in vivo Equivalent or similar to OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster) No data Acceptable Drosophila melanogaster (as animal) Not reported Male oral: feed no data not applicable Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) No data Acceptable House mouse (as animal) NMRI Male Not reported no data not applicable Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) No data Acceptable House mouse (as animal) ICR Male oral: feed 49.0000000000 D no data not applicable Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable House mouse (as animal) CD-1 Male/Female Not reported no data not applicable Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable House mouse (as animal) NMRI Male/Female Not reported no data not applicable Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI genome mutation other in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) Not reported Male intraperitoneal no data not applicable Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No data Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data with Negative no information RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No data Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data without Negative no information RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No data Acceptable Human (as organism) lymphocytes Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No data Acceptable Human (as organism) lymphocytes Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) WP100 Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) WP2 Not reported no data without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) WP100 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) WP2 Not reported no data with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable House mouse (as animal) NMRI Male/Female oral: unspecified 24.0000000000 h no data not applicable Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable House mouse (as animal) NMRI Male/Female oral: unspecified 72.0000000000 h no data not applicable Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable House mouse (as animal) NMRI Male/Female oral: unspecified 48.0000000000 h no data not applicable Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Hungary Amitrole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Hungary Amitrole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Hungary Amitrole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Hungary Amitrole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Hungary Amitrole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Hungary Amitrole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Hungary Amitrole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Hungary Amitrole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Hungary Amitrole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Hungary Amitrole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes without Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Amitrole 200-521-5 61-82-5 single chemical entity Component is identical to the substance Amitrole 200-521-5 61-82-5 1-H-1,2,4-triazol-3-amine Amitrole C2H4N4 C1=NNC(=N1)N InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes with Negative RMS: France Amitrole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole 01Jul2014 2014 doi:10.2903/j.efsa.2014.3742
+Fludioxonil 131341-86-1 single chemical entity Component is identical to the substance Fludioxonil 131341-86-1 4-(2,2-difluoro-1,3-benzodioxol-4-yl)-1H-pyrrole-3-carbonitrile Fludioxonil C12H6F2N2O2 FC3(F)OC(C(O3)=CC=C2)=C2C1=CNC=C1C#N InChI=1S/C12H6F2N2O2/c13-12(14)17-10-3-1-2-8(11(10)18-12)9-6-16-5-7(9)4-15/h1-3,5-6,16H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is identical to the substance Fludioxonil 131341-86-1 4-(2,2-difluoro-1,3-benzodioxol-4-yl)-1H-pyrrole-3-carbonitrile Fludioxonil C12H6F2N2O2 FC3(F)OC(C(O3)=CC=C2)=C2C1=CNC=C1C#N InChI=1S/C12H6F2N2O2/c13-12(14)17-10-3-1-2-8(11(10)18-12)9-6-16-5-7(9)4-15/h1-3,5-6,16H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is identical to the substance Fludioxonil 131341-86-1 4-(2,2-difluoro-1,3-benzodioxol-4-yl)-1H-pyrrole-3-carbonitrile Fludioxonil C12H6F2N2O2 FC3(F)OC(C(O3)=CC=C2)=C2C1=CNC=C1C#N InChI=1S/C12H6F2N2O2/c13-12(14)17-10-3-1-2-8(11(10)18-12)9-6-16-5-7(9)4-15/h1-3,5-6,16H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is identical to the substance Fludioxonil 131341-86-1 4-(2,2-difluoro-1,3-benzodioxol-4-yl)-1H-pyrrole-3-carbonitrile Fludioxonil C12H6F2N2O2 FC3(F)OC(C(O3)=CC=C2)=C2C1=CNC=C1C#N InChI=1S/C12H6F2N2O2/c13-12(14)17-10-3-1-2-8(11(10)18-12)9-6-16-5-7(9)4-15/h1-3,5-6,16H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is identical to the substance Fludioxonil 131341-86-1 4-(2,2-difluoro-1,3-benzodioxol-4-yl)-1H-pyrrole-3-carbonitrile Fludioxonil C12H6F2N2O2 FC3(F)OC(C(O3)=CC=C2)=C2C1=CNC=C1C#N InChI=1S/C12H6F2N2O2/c13-12(14)17-10-3-1-2-8(11(10)18-12)9-6-16-5-7(9)4-15/h1-3,5-6,16H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is identical to the substance Fludioxonil 131341-86-1 4-(2,2-difluoro-1,3-benzodioxol-4-yl)-1H-pyrrole-3-carbonitrile Fludioxonil C12H6F2N2O2 FC3(F)OC(C(O3)=CC=C2)=C2C1=CNC=C1C#N InChI=1S/C12H6F2N2O2/c13-12(14)17-10-3-1-2-8(11(10)18-12)9-6-16-5-7(9)4-15/h1-3,5-6,16H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is identical to the substance Fludioxonil 131341-86-1 4-(2,2-difluoro-1,3-benzodioxol-4-yl)-1H-pyrrole-3-carbonitrile Fludioxonil C12H6F2N2O2 FC3(F)OC(C(O3)=CC=C2)=C2C1=CNC=C1C#N InChI=1S/C12H6F2N2O2/c13-12(14)17-10-3-1-2-8(11(10)18-12)9-6-16-5-7(9)4-15/h1-3,5-6,16H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is identical to the substance Fludioxonil 131341-86-1 4-(2,2-difluoro-1,3-benzodioxol-4-yl)-1H-pyrrole-3-carbonitrile Fludioxonil C12H6F2N2O2 FC3(F)OC(C(O3)=CC=C2)=C2C1=CNC=C1C#N InChI=1S/C12H6F2N2O2/c13-12(14)17-10-3-1-2-8(11(10)18-12)9-6-16-5-7(9)4-15/h1-3,5-6,16H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is identical to the substance Fludioxonil 131341-86-1 4-(2,2-difluoro-1,3-benzodioxol-4-yl)-1H-pyrrole-3-carbonitrile Fludioxonil C12H6F2N2O2 FC3(F)OC(C(O3)=CC=C2)=C2C1=CNC=C1C#N InChI=1S/C12H6F2N2O2/c13-12(14)17-10-3-1-2-8(11(10)18-12)9-6-16-5-7(9)4-15/h1-3,5-6,16H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is identical to the substance Fludioxonil 131341-86-1 4-(2,2-difluoro-1,3-benzodioxol-4-yl)-1H-pyrrole-3-carbonitrile Fludioxonil C12H6F2N2O2 FC3(F)OC(C(O3)=CC=C2)=C2C1=CNC=C1C#N InChI=1S/C12H6F2N2O2/c13-12(14)17-10-3-1-2-8(11(10)18-12)9-6-16-5-7(9)4-15/h1-3,5-6,16H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is identical to the substance Fludioxonil 131341-86-1 4-(2,2-difluoro-1,3-benzodioxol-4-yl)-1H-pyrrole-3-carbonitrile Fludioxonil C12H6F2N2O2 FC3(F)OC(C(O3)=CC=C2)=C2C1=CNC=C1C#N InChI=1S/C12H6F2N2O2/c13-12(14)17-10-3-1-2-8(11(10)18-12)9-6-16-5-7(9)4-15/h1-3,5-6,16H organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is identical to the substance Fludioxonil 131341-86-1 4-(2,2-difluoro-1,3-benzodioxol-4-yl)-1H-pyrrole-3-carbonitrile Fludioxonil C12H6F2N2O2 FC3(F)OC(C(O3)=CC=C2)=C2C1=CNC=C1C#N InChI=1S/C12H6F2N2O2/c13-12(14)17-10-3-1-2-8(11(10)18-12)9-6-16-5-7(9)4-15/h1-3,5-6,16H organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is identical to the substance Fludioxonil 131341-86-1 4-(2,2-difluoro-1,3-benzodioxol-4-yl)-1H-pyrrole-3-carbonitrile Fludioxonil C12H6F2N2O2 FC3(F)OC(C(O3)=CC=C2)=C2C1=CNC=C1C#N InChI=1S/C12H6F2N2O2/c13-12(14)17-10-3-1-2-8(11(10)18-12)9-6-16-5-7(9)4-15/h1-3,5-6,16H organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Positive RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is identical to the substance Fludioxonil 131341-86-1 4-(2,2-difluoro-1,3-benzodioxol-4-yl)-1H-pyrrole-3-carbonitrile Fludioxonil C12H6F2N2O2 FC3(F)OC(C(O3)=CC=C2)=C2C1=CNC=C1C#N InChI=1S/C12H6F2N2O2/c13-12(14)17-10-3-1-2-8(11(10)18-12)9-6-16-5-7(9)4-15/h1-3,5-6,16H organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Positive RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is identical to the substance Fludioxonil 131341-86-1 4-(2,2-difluoro-1,3-benzodioxol-4-yl)-1H-pyrrole-3-carbonitrile Fludioxonil C12H6F2N2O2 FC3(F)OC(C(O3)=CC=C2)=C2C1=CNC=C1C#N InChI=1S/C12H6F2N2O2/c13-12(14)17-10-3-1-2-8(11(10)18-12)9-6-16-5-7(9)4-15/h1-3,5-6,16H organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle with Positive RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is identical to the substance Fludioxonil 131341-86-1 4-(2,2-difluoro-1,3-benzodioxol-4-yl)-1H-pyrrole-3-carbonitrile Fludioxonil C12H6F2N2O2 FC3(F)OC(C(O3)=CC=C2)=C2C1=CNC=C1C#N InChI=1S/C12H6F2N2O2/c13-12(14)17-10-3-1-2-8(11(10)18-12)9-6-16-5-7(9)4-15/h1-3,5-6,16H organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Hamster (as animal) Chinese 10 Male/Female oral: gavage 16.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is identical to the substance Fludioxonil 131341-86-1 4-(2,2-difluoro-1,3-benzodioxol-4-yl)-1H-pyrrole-3-carbonitrile Fludioxonil C12H6F2N2O2 FC3(F)OC(C(O3)=CC=C2)=C2C1=CNC=C1C#N InChI=1S/C12H6F2N2O2/c13-12(14)17-10-3-1-2-8(11(10)18-12)9-6-16-5-7(9)4-15/h1-3,5-6,16H organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Hamster (as animal) Chinese 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is identical to the substance Fludioxonil 131341-86-1 4-(2,2-difluoro-1,3-benzodioxol-4-yl)-1H-pyrrole-3-carbonitrile Fludioxonil C12H6F2N2O2 FC3(F)OC(C(O3)=CC=C2)=C2C1=CNC=C1C#N InChI=1S/C12H6F2N2O2/c13-12(14)17-10-3-1-2-8(11(10)18-12)9-6-16-5-7(9)4-15/h1-3,5-6,16H organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Hamster (as animal) Chinese 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is identical to the substance Fludioxonil 131341-86-1 4-(2,2-difluoro-1,3-benzodioxol-4-yl)-1H-pyrrole-3-carbonitrile Fludioxonil C12H6F2N2O2 FC3(F)OC(C(O3)=CC=C2)=C2C1=CNC=C1C#N InChI=1S/C12H6F2N2O2/c13-12(14)17-10-3-1-2-8(11(10)18-12)9-6-16-5-7(9)4-15/h1-3,5-6,16H organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Tif:MAGf(SPF) 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is identical to the substance Fludioxonil 131341-86-1 4-(2,2-difluoro-1,3-benzodioxol-4-yl)-1H-pyrrole-3-carbonitrile Fludioxonil C12H6F2N2O2 FC3(F)OC(C(O3)=CC=C2)=C2C1=CNC=C1C#N InChI=1S/C12H6F2N2O2/c13-12(14)17-10-3-1-2-8(11(10)18-12)9-6-16-5-7(9)4-15/h1-3,5-6,16H organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Tif:MAGf(SPF) 10 Male/Female oral: gavage 16.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is identical to the substance Fludioxonil 131341-86-1 4-(2,2-difluoro-1,3-benzodioxol-4-yl)-1H-pyrrole-3-carbonitrile Fludioxonil C12H6F2N2O2 FC3(F)OC(C(O3)=CC=C2)=C2C1=CNC=C1C#N InChI=1S/C12H6F2N2O2/c13-12(14)17-10-3-1-2-8(11(10)18-12)9-6-16-5-7(9)4-15/h1-3,5-6,16H organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Tif:MAGf(SPF) 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is identical to the substance Fludioxonil 131341-86-1 4-(2,2-difluoro-1,3-benzodioxol-4-yl)-1H-pyrrole-3-carbonitrile Fludioxonil C12H6F2N2O2 FC3(F)OC(C(O3)=CC=C2)=C2C1=CNC=C1C#N InChI=1S/C12H6F2N2O2/c13-12(14)17-10-3-1-2-8(11(10)18-12)9-6-16-5-7(9)4-15/h1-3,5-6,16H organic compound Other Other chromosome aberration other in vivo No guideline available Not reported Not applicable Acceptable Rat (as animal) Tif:RAIf(SPF) Rat 4 Male oral: gavage 3.0000000000 D yes, concurrent vehicle not applicable Ambiguous no evidence RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is identical to the substance Fludioxonil 131341-86-1 4-(2,2-difluoro-1,3-benzodioxol-4-yl)-1H-pyrrole-3-carbonitrile Fludioxonil C12H6F2N2O2 FC3(F)OC(C(O3)=CC=C2)=C2C1=CNC=C1C#N InChI=1S/C12H6F2N2O2/c13-12(14)17-10-3-1-2-8(11(10)18-12)9-6-16-5-7(9)4-15/h1-3,5-6,16H organic compound Other Other chromosome aberration other in vivo No guideline available Not reported Not applicable Acceptable Rat (as animal) Tif:RAIf(SPF) Rat 5 Male oral: gavage 3.0000000000 D yes, concurrent vehicle not applicable Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is identical to the substance Fludioxonil 131341-86-1 4-(2,2-difluoro-1,3-benzodioxol-4-yl)-1H-pyrrole-3-carbonitrile Fludioxonil C12H6F2N2O2 FC3(F)OC(C(O3)=CC=C2)=C2C1=CNC=C1C#N InChI=1S/C12H6F2N2O2/c13-12(14)17-10-3-1-2-8(11(10)18-12)9-6-16-5-7(9)4-15/h1-3,5-6,16H organic compound Other Other chromosome aberration other in vivo No guideline available Not reported Not applicable Acceptable Rat (as animal) Crj:CD(SD) 10 Male/Female oral: gavage 30.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is identical to the substance Fludioxonil 131341-86-1 4-(2,2-difluoro-1,3-benzodioxol-4-yl)-1H-pyrrole-3-carbonitrile Fludioxonil C12H6F2N2O2 FC3(F)OC(C(O3)=CC=C2)=C2C1=CNC=C1C#N InChI=1S/C12H6F2N2O2/c13-12(14)17-10-3-1-2-8(11(10)18-12)9-6-16-5-7(9)4-15/h1-3,5-6,16H organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Tif:RAIf(SPF) Rat 4 Male oral: gavage 4.0000000000 h yes not applicable Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is identical to the substance Fludioxonil 131341-86-1 4-(2,2-difluoro-1,3-benzodioxol-4-yl)-1H-pyrrole-3-carbonitrile Fludioxonil C12H6F2N2O2 FC3(F)OC(C(O3)=CC=C2)=C2C1=CNC=C1C#N InChI=1S/C12H6F2N2O2/c13-12(14)17-10-3-1-2-8(11(10)18-12)9-6-16-5-7(9)4-15/h1-3,5-6,16H organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Tif:RAIf(SPF) Rat 4 Male oral: gavage 2.0000000000 h yes not applicable Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is identical to the substance Fludioxonil 131341-86-1 4-(2,2-difluoro-1,3-benzodioxol-4-yl)-1H-pyrrole-3-carbonitrile Fludioxonil C12H6F2N2O2 FC3(F)OC(C(O3)=CC=C2)=C2C1=CNC=C1C#N InChI=1S/C12H6F2N2O2/c13-12(14)17-10-3-1-2-8(11(10)18-12)9-6-16-5-7(9)4-15/h1-3,5-6,16H organic compound Other Other chromosome aberration dominant lethal assay in vivo According to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) No Acceptable House mouse (as animal) Tif:MAGf(SPF) 30 Male oral: gavage yes not applicable Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is a metabolite of the substance (2,2-difluoro-benzo[1,3]dioxol-4-carbocyclic acid 2,2-difluoro-1,3-benzodioxole-4-carboxylic acid Not in list C8H4F2O4 O=C(O)c1cccc2OC(F)(F)Oc12 InChI=1/C8H4F2O4/c9-8(10)13-5-3-1-2-4(7(11)12)6(5)14-8/h1-3H,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is a metabolite of the substance (2,2-difluoro-benzo[1,3]dioxol-4-carbocyclic acid 2,2-difluoro-1,3-benzodioxole-4-carboxylic acid Not in list C8H4F2O4 O=C(O)c1cccc2OC(F)(F)Oc12 InChI=1/C8H4F2O4/c9-8(10)13-5-3-1-2-4(7(11)12)6(5)14-8/h1-3H,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is a metabolite of the substance (2,2-difluoro-benzo[1,3]dioxol-4-carbocyclic acid 2,2-difluoro-1,3-benzodioxole-4-carboxylic acid Not in list C8H4F2O4 O=C(O)c1cccc2OC(F)(F)Oc12 InChI=1/C8H4F2O4/c9-8(10)13-5-3-1-2-4(7(11)12)6(5)14-8/h1-3H,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is a metabolite of the substance (2,2-difluoro-benzo[1,3]dioxol-4-carbocyclic acid 2,2-difluoro-1,3-benzodioxole-4-carboxylic acid Not in list C8H4F2O4 O=C(O)c1cccc2OC(F)(F)Oc12 InChI=1/C8H4F2O4/c9-8(10)13-5-3-1-2-4(7(11)12)6(5)14-8/h1-3H,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is a metabolite of the substance (2,2-difluoro-benzo[1,3]dioxol-4-carbocyclic acid 2,2-difluoro-1,3-benzodioxole-4-carboxylic acid Not in list C8H4F2O4 O=C(O)c1cccc2OC(F)(F)Oc12 InChI=1/C8H4F2O4/c9-8(10)13-5-3-1-2-4(7(11)12)6(5)14-8/h1-3H,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is a metabolite of the substance (2,2-difluoro-benzo[1,3]dioxol-4-carbocyclic acid 2,2-difluoro-1,3-benzodioxole-4-carboxylic acid Not in list C8H4F2O4 O=C(O)c1cccc2OC(F)(F)Oc12 InChI=1/C8H4F2O4/c9-8(10)13-5-3-1-2-4(7(11)12)6(5)14-8/h1-3H,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is a metabolite of the substance (2,2-difluoro-benzo[1,3]dioxol-4-carbocyclic acid 2,2-difluoro-1,3-benzodioxole-4-carboxylic acid Not in list C8H4F2O4 O=C(O)c1cccc2OC(F)(F)Oc12 InChI=1/C8H4F2O4/c9-8(10)13-5-3-1-2-4(7(11)12)6(5)14-8/h1-3H,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is a metabolite of the substance (2,2-difluoro-benzo[1,3]dioxol-4-carbocyclic acid 2,2-difluoro-1,3-benzodioxole-4-carboxylic acid Not in list C8H4F2O4 O=C(O)c1cccc2OC(F)(F)Oc12 InChI=1/C8H4F2O4/c9-8(10)13-5-3-1-2-4(7(11)12)6(5)14-8/h1-3H,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is a metabolite of the substance (2,2-difluoro-benzo[1,3]dioxol-4-carbocyclic acid 2,2-difluoro-1,3-benzodioxole-4-carboxylic acid Not in list C8H4F2O4 O=C(O)c1cccc2OC(F)(F)Oc12 InChI=1/C8H4F2O4/c9-8(10)13-5-3-1-2-4(7(11)12)6(5)14-8/h1-3H,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is a metabolite of the substance (2,2-difluoro-benzo[1,3]dioxol-4-carbocyclic acid 2,2-difluoro-1,3-benzodioxole-4-carboxylic acid Not in list C8H4F2O4 O=C(O)c1cccc2OC(F)(F)Oc12 InChI=1/C8H4F2O4/c9-8(10)13-5-3-1-2-4(7(11)12)6(5)14-8/h1-3H,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is a metabolite of the substance 4-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrole-3-carbonitrile 4-(2,2-difluoro-1,3-benzodioxol-4-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrole-3-carbonitrile Not in list C12H4F2N2O4 N#CC=3C(=O)NC(=O)C=3c1cccc2OC(F)(F)Oc12 InChI=1/C12H4F2N2O4/c13-12(14)19-7-3-1-2-5(9(7)20-12)8-6(4-15)10(17)16-11(8)18/h1-3H,(H,16,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is a metabolite of the substance 4-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrole-3-carbonitrile 4-(2,2-difluoro-1,3-benzodioxol-4-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrole-3-carbonitrile Not in list C12H4F2N2O4 N#CC=3C(=O)NC(=O)C=3c1cccc2OC(F)(F)Oc12 InChI=1/C12H4F2N2O4/c13-12(14)19-7-3-1-2-5(9(7)20-12)8-6(4-15)10(17)16-11(8)18/h1-3H,(H,16,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is a metabolite of the substance 4-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrole-3-carbonitrile 4-(2,2-difluoro-1,3-benzodioxol-4-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrole-3-carbonitrile Not in list C12H4F2N2O4 N#CC=3C(=O)NC(=O)C=3c1cccc2OC(F)(F)Oc12 InChI=1/C12H4F2N2O4/c13-12(14)19-7-3-1-2-5(9(7)20-12)8-6(4-15)10(17)16-11(8)18/h1-3H,(H,16,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is a metabolite of the substance 4-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrole-3-carbonitrile 4-(2,2-difluoro-1,3-benzodioxol-4-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrole-3-carbonitrile Not in list C12H4F2N2O4 N#CC=3C(=O)NC(=O)C=3c1cccc2OC(F)(F)Oc12 InChI=1/C12H4F2N2O4/c13-12(14)19-7-3-1-2-5(9(7)20-12)8-6(4-15)10(17)16-11(8)18/h1-3H,(H,16,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is a metabolite of the substance 4-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrole-3-carbonitrile 4-(2,2-difluoro-1,3-benzodioxol-4-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrole-3-carbonitrile Not in list C12H4F2N2O4 N#CC=3C(=O)NC(=O)C=3c1cccc2OC(F)(F)Oc12 InChI=1/C12H4F2N2O4/c13-12(14)19-7-3-1-2-5(9(7)20-12)8-6(4-15)10(17)16-11(8)18/h1-3H,(H,16,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is a metabolite of the substance 4-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrole-3-carbonitrile 4-(2,2-difluoro-1,3-benzodioxol-4-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrole-3-carbonitrile Not in list C12H4F2N2O4 N#CC=3C(=O)NC(=O)C=3c1cccc2OC(F)(F)Oc12 InChI=1/C12H4F2N2O4/c13-12(14)19-7-3-1-2-5(9(7)20-12)8-6(4-15)10(17)16-11(8)18/h1-3H,(H,16,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is a metabolite of the substance 4-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrole-3-carbonitrile 4-(2,2-difluoro-1,3-benzodioxol-4-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrole-3-carbonitrile Not in list C12H4F2N2O4 N#CC=3C(=O)NC(=O)C=3c1cccc2OC(F)(F)Oc12 InChI=1/C12H4F2N2O4/c13-12(14)19-7-3-1-2-5(9(7)20-12)8-6(4-15)10(17)16-11(8)18/h1-3H,(H,16,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is a metabolite of the substance 4-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrole-3-carbonitrile 4-(2,2-difluoro-1,3-benzodioxol-4-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrole-3-carbonitrile Not in list C12H4F2N2O4 N#CC=3C(=O)NC(=O)C=3c1cccc2OC(F)(F)Oc12 InChI=1/C12H4F2N2O4/c13-12(14)19-7-3-1-2-5(9(7)20-12)8-6(4-15)10(17)16-11(8)18/h1-3H,(H,16,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is a metabolite of the substance 4-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrole-3-carbonitrile 4-(2,2-difluoro-1,3-benzodioxol-4-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrole-3-carbonitrile Not in list C12H4F2N2O4 N#CC=3C(=O)NC(=O)C=3c1cccc2OC(F)(F)Oc12 InChI=1/C12H4F2N2O4/c13-12(14)19-7-3-1-2-5(9(7)20-12)8-6(4-15)10(17)16-11(8)18/h1-3H,(H,16,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is a metabolite of the substance 4-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrole-3-carbonitrile 4-(2,2-difluoro-1,3-benzodioxol-4-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrole-3-carbonitrile Not in list C12H4F2N2O4 N#CC=3C(=O)NC(=O)C=3c1cccc2OC(F)(F)Oc12 InChI=1/C12H4F2N2O4/c13-12(14)19-7-3-1-2-5(9(7)20-12)8-6(4-15)10(17)16-11(8)18/h1-3H,(H,16,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is a metabolite of the substance 2-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-2-hydroxy-acetamide 2-(2,2-difluoro-1,3-benzodioxol-4-yl)-2-hydroxyacetamide Not in list C9H7F2NO4 NC(=O)C(O)c1cccc2OC(F)(F)Oc12 InChI=1/C9H7F2NO4/c10-9(11)15-5-3-1-2-4(7(5)16-9)6(13)8(12)14/h1-3,6,13H,(H2,12,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is a metabolite of the substance 2-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-2-hydroxy-acetamide 2-(2,2-difluoro-1,3-benzodioxol-4-yl)-2-hydroxyacetamide Not in list C9H7F2NO4 NC(=O)C(O)c1cccc2OC(F)(F)Oc12 InChI=1/C9H7F2NO4/c10-9(11)15-5-3-1-2-4(7(5)16-9)6(13)8(12)14/h1-3,6,13H,(H2,12,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is a metabolite of the substance 2-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-2-hydroxy-acetamide 2-(2,2-difluoro-1,3-benzodioxol-4-yl)-2-hydroxyacetamide Not in list C9H7F2NO4 NC(=O)C(O)c1cccc2OC(F)(F)Oc12 InChI=1/C9H7F2NO4/c10-9(11)15-5-3-1-2-4(7(5)16-9)6(13)8(12)14/h1-3,6,13H,(H2,12,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is a metabolite of the substance 2-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-2-hydroxy-acetamide 2-(2,2-difluoro-1,3-benzodioxol-4-yl)-2-hydroxyacetamide Not in list C9H7F2NO4 NC(=O)C(O)c1cccc2OC(F)(F)Oc12 InChI=1/C9H7F2NO4/c10-9(11)15-5-3-1-2-4(7(5)16-9)6(13)8(12)14/h1-3,6,13H,(H2,12,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is a metabolite of the substance 2-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-2-hydroxy-acetamide 2-(2,2-difluoro-1,3-benzodioxol-4-yl)-2-hydroxyacetamide Not in list C9H7F2NO4 NC(=O)C(O)c1cccc2OC(F)(F)Oc12 InChI=1/C9H7F2NO4/c10-9(11)15-5-3-1-2-4(7(5)16-9)6(13)8(12)14/h1-3,6,13H,(H2,12,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is a metabolite of the substance 2-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-2-hydroxy-acetamide 2-(2,2-difluoro-1,3-benzodioxol-4-yl)-2-hydroxyacetamide Not in list C9H7F2NO4 NC(=O)C(O)c1cccc2OC(F)(F)Oc12 InChI=1/C9H7F2NO4/c10-9(11)15-5-3-1-2-4(7(5)16-9)6(13)8(12)14/h1-3,6,13H,(H2,12,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is a metabolite of the substance 2-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-2-hydroxy-acetamide 2-(2,2-difluoro-1,3-benzodioxol-4-yl)-2-hydroxyacetamide Not in list C9H7F2NO4 NC(=O)C(O)c1cccc2OC(F)(F)Oc12 InChI=1/C9H7F2NO4/c10-9(11)15-5-3-1-2-4(7(5)16-9)6(13)8(12)14/h1-3,6,13H,(H2,12,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is a metabolite of the substance 2-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-2-hydroxy-acetamide 2-(2,2-difluoro-1,3-benzodioxol-4-yl)-2-hydroxyacetamide Not in list C9H7F2NO4 NC(=O)C(O)c1cccc2OC(F)(F)Oc12 InChI=1/C9H7F2NO4/c10-9(11)15-5-3-1-2-4(7(5)16-9)6(13)8(12)14/h1-3,6,13H,(H2,12,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is a metabolite of the substance 2-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-2-hydroxy-acetamide 2-(2,2-difluoro-1,3-benzodioxol-4-yl)-2-hydroxyacetamide Not in list C9H7F2NO4 NC(=O)C(O)c1cccc2OC(F)(F)Oc12 InChI=1/C9H7F2NO4/c10-9(11)15-5-3-1-2-4(7(5)16-9)6(13)8(12)14/h1-3,6,13H,(H2,12,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is a metabolite of the substance 2-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-2-hydroxy-acetamide 2-(2,2-difluoro-1,3-benzodioxol-4-yl)-2-hydroxyacetamide Not in list C9H7F2NO4 NC(=O)C(O)c1cccc2OC(F)(F)Oc12 InChI=1/C9H7F2NO4/c10-9(11)15-5-3-1-2-4(7(5)16-9)6(13)8(12)14/h1-3,6,13H,(H2,12,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is a metabolite of the substance 4-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-2,5-dioxo-pyrrolidine-3-carbonitrile 4-(2,2-difluoro-1,3-benzodioxol-4-yl)-2,5-dioxopyrrolidine-3-carbonitrile Not in list C12H6F2N2O4 O=C3NC(=O)C(C#N)C3c1cccc2OC(F)(F)Oc12 InChI=1/C12H6F2N2O4/c13-12(14)19-7-3-1-2-5(9(7)20-12)8-6(4-15)10(17)16-11(8)18/h1-3,6,8H,(H,16,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is a metabolite of the substance 4-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-2,5-dioxo-pyrrolidine-3-carbonitrile 4-(2,2-difluoro-1,3-benzodioxol-4-yl)-2,5-dioxopyrrolidine-3-carbonitrile Not in list C12H6F2N2O4 O=C3NC(=O)C(C#N)C3c1cccc2OC(F)(F)Oc12 InChI=1/C12H6F2N2O4/c13-12(14)19-7-3-1-2-5(9(7)20-12)8-6(4-15)10(17)16-11(8)18/h1-3,6,8H,(H,16,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is a metabolite of the substance 4-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-2,5-dioxo-pyrrolidine-3-carbonitrile 4-(2,2-difluoro-1,3-benzodioxol-4-yl)-2,5-dioxopyrrolidine-3-carbonitrile Not in list C12H6F2N2O4 O=C3NC(=O)C(C#N)C3c1cccc2OC(F)(F)Oc12 InChI=1/C12H6F2N2O4/c13-12(14)19-7-3-1-2-5(9(7)20-12)8-6(4-15)10(17)16-11(8)18/h1-3,6,8H,(H,16,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is a metabolite of the substance 4-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-2,5-dioxo-pyrrolidine-3-carbonitrile 4-(2,2-difluoro-1,3-benzodioxol-4-yl)-2,5-dioxopyrrolidine-3-carbonitrile Not in list C12H6F2N2O4 O=C3NC(=O)C(C#N)C3c1cccc2OC(F)(F)Oc12 InChI=1/C12H6F2N2O4/c13-12(14)19-7-3-1-2-5(9(7)20-12)8-6(4-15)10(17)16-11(8)18/h1-3,6,8H,(H,16,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is a metabolite of the substance 4-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-2,5-dioxo-pyrrolidine-3-carbonitrile 4-(2,2-difluoro-1,3-benzodioxol-4-yl)-2,5-dioxopyrrolidine-3-carbonitrile Not in list C12H6F2N2O4 O=C3NC(=O)C(C#N)C3c1cccc2OC(F)(F)Oc12 InChI=1/C12H6F2N2O4/c13-12(14)19-7-3-1-2-5(9(7)20-12)8-6(4-15)10(17)16-11(8)18/h1-3,6,8H,(H,16,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is a metabolite of the substance 4-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-2,5-dioxo-pyrrolidine-3-carbonitrile 4-(2,2-difluoro-1,3-benzodioxol-4-yl)-2,5-dioxopyrrolidine-3-carbonitrile Not in list C12H6F2N2O4 O=C3NC(=O)C(C#N)C3c1cccc2OC(F)(F)Oc12 InChI=1/C12H6F2N2O4/c13-12(14)19-7-3-1-2-5(9(7)20-12)8-6(4-15)10(17)16-11(8)18/h1-3,6,8H,(H,16,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is a metabolite of the substance 4-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-2,5-dioxo-pyrrolidine-3-carbonitrile 4-(2,2-difluoro-1,3-benzodioxol-4-yl)-2,5-dioxopyrrolidine-3-carbonitrile Not in list C12H6F2N2O4 O=C3NC(=O)C(C#N)C3c1cccc2OC(F)(F)Oc12 InChI=1/C12H6F2N2O4/c13-12(14)19-7-3-1-2-5(9(7)20-12)8-6(4-15)10(17)16-11(8)18/h1-3,6,8H,(H,16,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is a metabolite of the substance 4-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-2,5-dioxo-pyrrolidine-3-carbonitrile 4-(2,2-difluoro-1,3-benzodioxol-4-yl)-2,5-dioxopyrrolidine-3-carbonitrile Not in list C12H6F2N2O4 O=C3NC(=O)C(C#N)C3c1cccc2OC(F)(F)Oc12 InChI=1/C12H6F2N2O4/c13-12(14)19-7-3-1-2-5(9(7)20-12)8-6(4-15)10(17)16-11(8)18/h1-3,6,8H,(H,16,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is a metabolite of the substance 4-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-2,5-dioxo-pyrrolidine-3-carbonitrile 4-(2,2-difluoro-1,3-benzodioxol-4-yl)-2,5-dioxopyrrolidine-3-carbonitrile Not in list C12H6F2N2O4 O=C3NC(=O)C(C#N)C3c1cccc2OC(F)(F)Oc12 InChI=1/C12H6F2N2O4/c13-12(14)19-7-3-1-2-5(9(7)20-12)8-6(4-15)10(17)16-11(8)18/h1-3,6,8H,(H,16,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is a metabolite of the substance 4-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-2,5-dioxo-pyrrolidine-3-carbonitrile 4-(2,2-difluoro-1,3-benzodioxol-4-yl)-2,5-dioxopyrrolidine-3-carbonitrile Not in list C12H6F2N2O4 O=C3NC(=O)C(C#N)C3c1cccc2OC(F)(F)Oc12 InChI=1/C12H6F2N2O4/c13-12(14)19-7-3-1-2-5(9(7)20-12)8-6(4-15)10(17)16-11(8)18/h1-3,6,8H,(H,16,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is a metabolite of the substance 3-carbamoyl-2-cyano-3-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-oxirane-2-carbocyclic acid 3-carbamoyl-2-cyano-3-(2,2-difluoro-1,3-benzodioxol-4-yl)oxirane-2-carboxylic acid Not in list C12H6F2N2O6 O=C(O)C3(C#N)OC3(c1cccc2OC(F)(F)Oc12)C(N)=O InChI=1/C12H6F2N2O6/c13-12(14)20-6-3-1-2-5(7(6)21-12)11(8(16)17)10(4-15,22-11)9(18)19/h1-3H,(H2,16,17)(H,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is a metabolite of the substance 3-carbamoyl-2-cyano-3-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-oxirane-2-carbocyclic acid 3-carbamoyl-2-cyano-3-(2,2-difluoro-1,3-benzodioxol-4-yl)oxirane-2-carboxylic acid Not in list C12H6F2N2O6 O=C(O)C3(C#N)OC3(c1cccc2OC(F)(F)Oc12)C(N)=O InChI=1/C12H6F2N2O6/c13-12(14)20-6-3-1-2-5(7(6)21-12)11(8(16)17)10(4-15,22-11)9(18)19/h1-3H,(H2,16,17)(H,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is a metabolite of the substance 3-carbamoyl-2-cyano-3-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-oxirane-2-carbocyclic acid 3-carbamoyl-2-cyano-3-(2,2-difluoro-1,3-benzodioxol-4-yl)oxirane-2-carboxylic acid Not in list C12H6F2N2O6 O=C(O)C3(C#N)OC3(c1cccc2OC(F)(F)Oc12)C(N)=O InChI=1/C12H6F2N2O6/c13-12(14)20-6-3-1-2-5(7(6)21-12)11(8(16)17)10(4-15,22-11)9(18)19/h1-3H,(H2,16,17)(H,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is a metabolite of the substance 3-carbamoyl-2-cyano-3-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-oxirane-2-carbocyclic acid 3-carbamoyl-2-cyano-3-(2,2-difluoro-1,3-benzodioxol-4-yl)oxirane-2-carboxylic acid Not in list C12H6F2N2O6 O=C(O)C3(C#N)OC3(c1cccc2OC(F)(F)Oc12)C(N)=O InChI=1/C12H6F2N2O6/c13-12(14)20-6-3-1-2-5(7(6)21-12)11(8(16)17)10(4-15,22-11)9(18)19/h1-3H,(H2,16,17)(H,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is a metabolite of the substance 3-carbamoyl-2-cyano-3-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-oxirane-2-carbocyclic acid 3-carbamoyl-2-cyano-3-(2,2-difluoro-1,3-benzodioxol-4-yl)oxirane-2-carboxylic acid Not in list C12H6F2N2O6 O=C(O)C3(C#N)OC3(c1cccc2OC(F)(F)Oc12)C(N)=O InChI=1/C12H6F2N2O6/c13-12(14)20-6-3-1-2-5(7(6)21-12)11(8(16)17)10(4-15,22-11)9(18)19/h1-3H,(H2,16,17)(H,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is a metabolite of the substance 3-carbamoyl-2-cyano-3-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-oxirane-2-carbocyclic acid 3-carbamoyl-2-cyano-3-(2,2-difluoro-1,3-benzodioxol-4-yl)oxirane-2-carboxylic acid Not in list C12H6F2N2O6 O=C(O)C3(C#N)OC3(c1cccc2OC(F)(F)Oc12)C(N)=O InChI=1/C12H6F2N2O6/c13-12(14)20-6-3-1-2-5(7(6)21-12)11(8(16)17)10(4-15,22-11)9(18)19/h1-3H,(H2,16,17)(H,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is a metabolite of the substance 3-carbamoyl-2-cyano-3-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-oxirane-2-carbocyclic acid 3-carbamoyl-2-cyano-3-(2,2-difluoro-1,3-benzodioxol-4-yl)oxirane-2-carboxylic acid Not in list C12H6F2N2O6 O=C(O)C3(C#N)OC3(c1cccc2OC(F)(F)Oc12)C(N)=O InChI=1/C12H6F2N2O6/c13-12(14)20-6-3-1-2-5(7(6)21-12)11(8(16)17)10(4-15,22-11)9(18)19/h1-3H,(H2,16,17)(H,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is a metabolite of the substance 3-carbamoyl-2-cyano-3-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-oxirane-2-carbocyclic acid 3-carbamoyl-2-cyano-3-(2,2-difluoro-1,3-benzodioxol-4-yl)oxirane-2-carboxylic acid Not in list C12H6F2N2O6 O=C(O)C3(C#N)OC3(c1cccc2OC(F)(F)Oc12)C(N)=O InChI=1/C12H6F2N2O6/c13-12(14)20-6-3-1-2-5(7(6)21-12)11(8(16)17)10(4-15,22-11)9(18)19/h1-3H,(H2,16,17)(H,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is a metabolite of the substance 3-carbamoyl-2-cyano-3-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-oxirane-2-carbocyclic acid 3-carbamoyl-2-cyano-3-(2,2-difluoro-1,3-benzodioxol-4-yl)oxirane-2-carboxylic acid Not in list C12H6F2N2O6 O=C(O)C3(C#N)OC3(c1cccc2OC(F)(F)Oc12)C(N)=O InChI=1/C12H6F2N2O6/c13-12(14)20-6-3-1-2-5(7(6)21-12)11(8(16)17)10(4-15,22-11)9(18)19/h1-3H,(H2,16,17)(H,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is a metabolite of the substance 3-carbamoyl-2-cyano-3-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-oxirane-2-carbocyclic acid 3-carbamoyl-2-cyano-3-(2,2-difluoro-1,3-benzodioxol-4-yl)oxirane-2-carboxylic acid Not in list C12H6F2N2O6 O=C(O)C3(C#N)OC3(c1cccc2OC(F)(F)Oc12)C(N)=O InChI=1/C12H6F2N2O6/c13-12(14)20-6-3-1-2-5(7(6)21-12)11(8(16)17)10(4-15,22-11)9(18)19/h1-3H,(H2,16,17)(H,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is a metabolite of the substance 3-carbamoyl-2-cyano-3-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-oxirane-2-carbocyclic acid 3-carbamoyl-2-cyano-3-(2,2-difluoro-1,3-benzodioxol-4-yl)oxirane-2-carboxylic acid Not in list C12H6F2N2O6 O=C(O)C3(C#N)OC3(c1cccc2OC(F)(F)Oc12)C(N)=O InChI=1/C12H6F2N2O6/c13-12(14)20-6-3-1-2-5(7(6)21-12)11(8(16)17)10(4-15,22-11)9(18)19/h1-3H,(H2,16,17)(H,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is a metabolite of the substance 3-carbamoyl-2-cyano-3-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-oxirane-2-carbocyclic acid 3-carbamoyl-2-cyano-3-(2,2-difluoro-1,3-benzodioxol-4-yl)oxirane-2-carboxylic acid Not in list C12H6F2N2O6 O=C(O)C3(C#N)OC3(c1cccc2OC(F)(F)Oc12)C(N)=O InChI=1/C12H6F2N2O6/c13-12(14)20-6-3-1-2-5(7(6)21-12)11(8(16)17)10(4-15,22-11)9(18)19/h1-3H,(H2,16,17)(H,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is a metabolite of the substance 3-carbamoyl-2-cyano-3-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-oxirane-2-carbocyclic acid 3-carbamoyl-2-cyano-3-(2,2-difluoro-1,3-benzodioxol-4-yl)oxirane-2-carboxylic acid Not in list C12H6F2N2O6 O=C(O)C3(C#N)OC3(c1cccc2OC(F)(F)Oc12)C(N)=O InChI=1/C12H6F2N2O6/c13-12(14)20-6-3-1-2-5(7(6)21-12)11(8(16)17)10(4-15,22-11)9(18)19/h1-3H,(H2,16,17)(H,18,19) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is a metabolite of the substance 3-carbamoyl-2-cyano-3-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-oxirane-2-carbocyclic acid 3-carbamoyl-2-cyano-3-(2,2-difluoro-1,3-benzodioxol-4-yl)oxirane-2-carboxylic acid Not in list C12H6F2N2O6 O=C(O)C3(C#N)OC3(c1cccc2OC(F)(F)Oc12)C(N)=O InChI=1/C12H6F2N2O6/c13-12(14)20-6-3-1-2-5(7(6)21-12)11(8(16)17)10(4-15,22-11)9(18)19/h1-3H,(H2,16,17)(H,18,19) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Ambiguous no information RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is a metabolite of the substance 3-carbamoyl-2-cyano-3-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-oxirane-2-carbocyclic acid 3-carbamoyl-2-cyano-3-(2,2-difluoro-1,3-benzodioxol-4-yl)oxirane-2-carboxylic acid Not in list C12H6F2N2O6 O=C(O)C3(C#N)OC3(c1cccc2OC(F)(F)Oc12)C(N)=O InChI=1/C12H6F2N2O6/c13-12(14)20-6-3-1-2-5(7(6)21-12)11(8(16)17)10(4-15,22-11)9(18)19/h1-3H,(H2,16,17)(H,18,19) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is a metabolite of the substance 3-carbamoyl-2-cyano-3-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-oxirane-2-carbocyclic acid 3-carbamoyl-2-cyano-3-(2,2-difluoro-1,3-benzodioxol-4-yl)oxirane-2-carboxylic acid Not in list C12H6F2N2O6 O=C(O)C3(C#N)OC3(c1cccc2OC(F)(F)Oc12)C(N)=O InChI=1/C12H6F2N2O6/c13-12(14)20-6-3-1-2-5(7(6)21-12)11(8(16)17)10(4-15,22-11)9(18)19/h1-3H,(H2,16,17)(H,18,19) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Positive RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is a metabolite of the substance 3-carbamoyl-2-cyano-3-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-oxirane-2-carbocyclic acid 3-carbamoyl-2-cyano-3-(2,2-difluoro-1,3-benzodioxol-4-yl)oxirane-2-carboxylic acid Not in list C12H6F2N2O6 O=C(O)C3(C#N)OC3(c1cccc2OC(F)(F)Oc12)C(N)=O InChI=1/C12H6F2N2O6/c13-12(14)20-6-3-1-2-5(7(6)21-12)11(8(16)17)10(4-15,22-11)9(18)19/h1-3H,(H2,16,17)(H,18,19) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable Rat (as animal) Alpk:APf SD Rat 5 Male oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+Fludioxonil 131341-86-1 single chemical entity Component is a metabolite of the substance 3-carbamoyl-2-cyano-3-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-oxirane-2-carbocyclic acid 3-carbamoyl-2-cyano-3-(2,2-difluoro-1,3-benzodioxol-4-yl)oxirane-2-carboxylic acid Not in list C12H6F2N2O6 O=C(O)C3(C#N)OC3(c1cccc2OC(F)(F)Oc12)C(N)=O InChI=1/C12H6F2N2O6/c13-12(14)20-6-3-1-2-5(7(6)21-12)11(8(16)17)10(4-15,22-11)9(18)19/h1-3H,(H2,16,17)(H,18,19) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable Rat (as animal) Wistar 5 Male oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Denmark Fludioxonil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil 17Aug2007 2007 doi:10.2903/j.efsa.2007.110r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle with Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported no data no data Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) Yes Acceptable House mouse (as animal) Not reported Male oral: gavage yes not applicable Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported no data no data Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle with Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) C3076 Not reported yes, concurrent vehicle with Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) G46 Not reported yes, concurrent vehicle with Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) G46 Not reported yes, concurrent vehicle without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Rat (as animal) hepatocytes Not reported yes without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) C3052 Not reported yes, concurrent vehicle without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) C3052 Not reported yes, concurrent vehicle with Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) C3076 Not reported yes, concurrent vehicle without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) G46 Not reported yes, concurrent vehicle without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) C3052 Not reported yes, concurrent vehicle without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) C3076 Not reported yes, concurrent vehicle without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) C3076 Not reported yes, concurrent vehicle with Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle with Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) G46 Not reported yes, concurrent vehicle with Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) C3052 Not reported yes, concurrent vehicle with Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) G46 Not reported yes, concurrent vehicle with Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) C3076 Not reported yes, concurrent vehicle without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle with Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) C3052 Not reported yes, concurrent vehicle with Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) C3076 Not reported yes, concurrent vehicle with Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) G46 Not reported yes, concurrent vehicle without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) C3052 Not reported yes, concurrent vehicle without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Human (as organism) Not reported Not reported no data without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Human (as organism) Not reported Not reported no data with Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Positive no information RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Negative no information RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Positive no information RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI genome mutation Drosophila SLRL test in vivo Equivalent or similar to OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster) Yes Acceptable Drosophila melanogaster (as animal) Not reported Male other no data not applicable Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI genome mutation Drosophila SLRL test in vivo Equivalent or similar to OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster) Yes Acceptable Drosophila melanogaster (as animal) Not reported Male oral: feed no data not applicable Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) Yes Acceptable Hamster (as animal) CHO Not reported no data no data Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported no data no data Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data no data Positive no information RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes without Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) Yes Acceptable Hamster (as animal) CHO Not reported yes without Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is part of a group assessment 2-Phenylphenol sodium salt 205-055-6 132-27-4 2-Phenylphenol sodium salt Not in list C12H9NaO C1=CC=C(C=C1)C2=CC=CC=C2[O-].[Na+] InChI=1S/C12H10O.Na/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10;/h1-9,13H;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported no data without Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is a metabolite of the substance Phenylhydroquinone 1079-21-6 2-phenylbenzene-1,4-diol Not in list C12H10O2 C1=CC=C(C=C1)C2=C(C=CC(=C2)O)O InChI=1S/C12H10O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8,13-14H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) Yes Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is a metabolite of the substance Phenylhydroquinone 1079-21-6 2-phenylbenzene-1,4-diol Not in list C12H10O2 C1=CC=C(C=C1)C2=C(C=CC(=C2)O)O InChI=1S/C12H10O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8,13-14H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes with Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) Yes Acceptable Hamster (as animal) CHO Not reported yes with Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes with Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is a metabolite of the substance Phenylhydroquinone 1079-21-6 2-phenylbenzene-1,4-diol Not in list C12H10O2 C1=CC=C(C=C1)C2=C(C=CC(=C2)O)O InChI=1S/C12H10O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8,13-14H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) Yes Acceptable Hamster (as animal) CHO Not reported yes without Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is a metabolite of the substance Phenylhydroquinone 1079-21-6 2-phenylbenzene-1,4-diol Not in list C12H10O2 C1=CC=C(C=C1)C2=C(C=CC(=C2)O)O InChI=1S/C12H10O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8,13-14H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes without Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) Yes Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is a metabolite of the substance Phenylhydroquinone 1079-21-6 2-phenylbenzene-1,4-diol Not in list C12H10O2 C1=CC=C(C=C1)C2=C(C=CC(=C2)O)O InChI=1S/C12H10O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8,13-14H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes without Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is a metabolite of the substance Phenylbenzoquinone 363-03-1 2-phenylcyclohexa-2,5-diene-1,4-dione Not in list C12H8O2 C1=CC=C(C=C1)C2=CC(=O)C=CC2=O InChI=1S/C12H8O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) Yes Acceptable Hamster (as animal) CHO Not reported yes without Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is a metabolite of the substance Phenylbenzoquinone 363-03-1 2-phenylcyclohexa-2,5-diene-1,4-dione Not in list C12H8O2 C1=CC=C(C=C1)C2=CC(=O)C=CC2=O InChI=1S/C12H8O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes without Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is a metabolite of the substance Phenylbenzoquinone 363-03-1 2-phenylcyclohexa-2,5-diene-1,4-dione Not in list C12H8O2 C1=CC=C(C=C1)C2=CC(=O)C=CC2=O InChI=1S/C12H8O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) Yes Acceptable Hamster (as animal) CHO Not reported yes with Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is a metabolite of the substance Phenylbenzoquinone 363-03-1 2-phenylcyclohexa-2,5-diene-1,4-dione Not in list C12H8O2 C1=CC=C(C=C1)C2=CC(=O)C=CC2=O InChI=1S/C12H8O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes with Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is a metabolite of the substance Phenylhydroquinone 1079-21-6 2-phenylbenzene-1,4-diol Not in list C12H10O2 C1=CC=C(C=C1)C2=C(C=CC(=C2)O)O InChI=1S/C12H10O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8,13-14H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is a metabolite of the substance Phenylhydroquinone 1079-21-6 2-phenylbenzene-1,4-diol Not in list C12H10O2 C1=CC=C(C=C1)C2=C(C=CC(=C2)O)O InChI=1S/C12H10O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8,13-14H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) Yes Acceptable Hamster (as animal) CHO Not reported yes without Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) Yes Acceptable Hamster (as animal) CHO Not reported yes with Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes without Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) Yes Acceptable Hamster (as animal) CHO Not reported yes without Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is a metabolite of the substance Phenylhydroquinone 1079-21-6 2-phenylbenzene-1,4-diol Not in list C12H10O2 C1=CC=C(C=C1)C2=C(C=CC(=C2)O)O InChI=1S/C12H10O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8,13-14H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) Yes Acceptable Hamster (as animal) CHO Not reported yes with Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is a metabolite of the substance Phenylhydroquinone 1079-21-6 2-phenylbenzene-1,4-diol Not in list C12H10O2 C1=CC=C(C=C1)C2=C(C=CC(=C2)O)O InChI=1S/C12H10O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8,13-14H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vitro No guideline available Not reported Not applicable Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes no data Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is a metabolite of the substance Phenylhydroquinone 1079-21-6 2-phenylbenzene-1,4-diol Not in list C12H10O2 C1=CC=C(C=C1)C2=C(C=CC(=C2)O)O InChI=1S/C12H10O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8,13-14H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vitro No guideline available Not reported Not applicable Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes no data Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is a metabolite of the substance Phenylbenzoquinone 363-03-1 2-phenylcyclohexa-2,5-diene-1,4-dione Not in list C12H8O2 C1=CC=C(C=C1)C2=CC(=O)C=CC2=O InChI=1S/C12H8O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vitro No guideline available Not reported Not applicable Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is a metabolite of the substance Phenylbenzoquinone 363-03-1 2-phenylcyclohexa-2,5-diene-1,4-dione Not in list C12H8O2 C1=CC=C(C=C1)C2=CC(=O)C=CC2=O InChI=1S/C12H8O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) CM571 Not reported no data no data Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data no data Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) WP2 Not reported no data no data Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) WP100 Not reported no data no data Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is a metabolite of the substance Phenylbenzoquinone 363-03-1 2-phenylcyclohexa-2,5-diene-1,4-dione Not in list C12H8O2 C1=CC=C(C=C1)C2=CC(=O)C=CC2=O InChI=1S/C12H8O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Other Not reported Not reported no data without Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Other Not reported Not reported no data without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is a metabolite of the substance Phenylhydroquinone 1079-21-6 2-phenylbenzene-1,4-diol Not in list C12H10O2 C1=CC=C(C=C1)C2=C(C=CC(=C2)O)O InChI=1S/C12H10O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8,13-14H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Other Not reported Not reported no data without Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Other Not reported Not reported no data without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is a metabolite of the substance Phenylhydroquinone 1079-21-6 2-phenylbenzene-1,4-diol Not in list C12H10O2 C1=CC=C(C=C1)C2=C(C=CC(=C2)O)O InChI=1S/C12H10O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8,13-14H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Other Not reported Not reported no data without Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Other Not reported Not reported no data with Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is a metabolite of the substance Phenylbenzoquinone 363-03-1 2-phenylcyclohexa-2,5-diene-1,4-dione Not in list C12H8O2 C1=CC=C(C=C1)C2=CC(=O)C=CC2=O InChI=1S/C12H8O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Other Not reported Not reported no data with Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is a metabolite of the substance Phenylhydroquinone 1079-21-6 2-phenylbenzene-1,4-diol Not in list C12H10O2 C1=CC=C(C=C1)C2=C(C=CC(=C2)O)O InChI=1S/C12H10O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8,13-14H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Other Not reported Not reported no data with Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is a metabolite of the substance Phenylbenzoquinone 363-03-1 2-phenylcyclohexa-2,5-diene-1,4-dione Not in list C12H8O2 C1=CC=C(C=C1)C2=CC(=O)C=CC2=O InChI=1S/C12H8O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Other Not reported Not reported no data without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is a metabolite of the substance Phenylhydroquinone 1079-21-6 2-phenylbenzene-1,4-diol Not in list C12H10O2 C1=CC=C(C=C1)C2=C(C=CC(=C2)O)O InChI=1S/C12H10O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8,13-14H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Bovinae (bovines = Tribe bovini) (as animal) Thymus cell Not reported no data no data Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is a metabolite of the substance Phenylbenzoquinone 363-03-1 2-phenylcyclohexa-2,5-diene-1,4-dione Not in list C12H8O2 C1=CC=C(C=C1)C2=CC(=O)C=CC2=O InChI=1S/C12H8O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Bovinae (bovines = Tribe bovini) (as animal) Thymus cell Not reported no data no data Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Bovinae (bovines = Tribe bovini) (as animal) Thymus cell Not reported no data no data Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is a metabolite of the substance Phenylbenzoquinone 363-03-1 2-phenylcyclohexa-2,5-diene-1,4-dione Not in list C12H8O2 C1=CC=C(C=C1)C2=CC(=O)C=CC2=O InChI=1S/C12H8O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Human (as organism) leukemia cells (HL-60) Not reported yes, concurrent vehicle no data Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is a metabolite of the substance Phenylbenzoquinone 363-03-1 2-phenylcyclohexa-2,5-diene-1,4-dione Not in list C12H8O2 C1=CC=C(C=C1)C2=CC(=O)C=CC2=O InChI=1S/C12H8O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Human (as organism) leukemia cells (HL-60) Not reported yes, concurrent vehicle no data Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is a metabolite of the substance Phenylhydroquinone 1079-21-6 2-phenylbenzene-1,4-diol Not in list C12H10O2 C1=CC=C(C=C1)C2=C(C=CC(=C2)O)O InChI=1S/C12H10O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8,13-14H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Human (as organism) leukemia cells (HL-60) Not reported yes, concurrent vehicle no data Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is a metabolite of the substance Phenylbenzoquinone 363-03-1 2-phenylcyclohexa-2,5-diene-1,4-dione Not in list C12H8O2 C1=CC=C(C=C1)C2=CC(=O)C=CC2=O InChI=1S/C12H8O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline followed Not reported Not applicable Acceptable Human (as organism) leukemia cells (HL-60) Not reported yes, concurrent vehicle no data Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is a metabolite of the substance Phenylhydroquinone 1079-21-6 2-phenylbenzene-1,4-diol Not in list C12H10O2 C1=CC=C(C=C1)C2=C(C=CC(=C2)O)O InChI=1S/C12H10O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8,13-14H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Human (as organism) leukemia cells (HL-60) Not reported yes, concurrent vehicle no data Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is a metabolite of the substance Phenylhydroquinone 1079-21-6 2-phenylbenzene-1,4-diol Not in list C12H10O2 C1=CC=C(C=C1)C2=C(C=CC(=C2)O)O InChI=1S/C12H10O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8,13-14H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Human (as organism) leukemia cells (HL-60) Not reported yes, concurrent vehicle no data Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is a metabolite of the substance Phenylbenzoquinone 363-03-1 2-phenylcyclohexa-2,5-diene-1,4-dione Not in list C12H8O2 C1=CC=C(C=C1)C2=CC(=O)C=CC2=O InChI=1S/C12H8O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Human (as organism) leukemia cells (HL-60) Not reported yes, concurrent vehicle no data Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is a metabolite of the substance Phenylhydroquinone 1079-21-6 2-phenylbenzene-1,4-diol Not in list C12H10O2 C1=CC=C(C=C1)C2=C(C=CC(=C2)O)O InChI=1S/C12H10O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8,13-14H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Human (as organism) leukemia cells (HL-60) Not reported yes, concurrent vehicle no data Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is part of a group assessment 2-Phenylphenol sodium salt 205-055-6 132-27-4 2-Phenylphenol sodium salt Not in list C12H9NaO C1=CC=C(C=C1)C2=CC=CC=C2[O-].[Na+] InChI=1S/C12H10O.Na/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10;/h1-9,13H;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable Rat (as animal) Fischer344 6 No data oral: feed 13.0000000000 week no data not applicable Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is a metabolite of the substance Phenylhydroquinone 1079-21-6 2-phenylbenzene-1,4-diol Not in list C12H10O2 C1=CC=C(C=C1)C2=C(C=CC(=C2)O)O InChI=1S/C12H10O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8,13-14H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Bovinae (bovines = Tribe bovini) (as animal) Thymus cell Not reported no data without Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is a metabolite of the substance Phenylbenzoquinone 363-03-1 2-phenylcyclohexa-2,5-diene-1,4-dione Not in list C12H8O2 C1=CC=C(C=C1)C2=CC(=O)C=CC2=O InChI=1S/C12H8O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Bovinae (bovines = Tribe bovini) (as animal) Thymus cell Not reported no data without Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Bovinae (bovines = Tribe bovini) (as animal) Thymus cell Not reported no data with Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Bovinae (bovines = Tribe bovini) (as animal) Thymus cell Not reported no data without Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is a metabolite of the substance Phenylhydroquinone 1079-21-6 2-phenylbenzene-1,4-diol Not in list C12H10O2 C1=CC=C(C=C1)C2=C(C=CC(=C2)O)O InChI=1S/C12H10O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8,13-14H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Human (as organism) Hep G2 human cell line Not reported no data no data Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Wistar Male/Female oral: unspecified 24.0000000000 h no data not applicable Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration other in vivo No guideline available Not reported Not applicable Acceptable Rat (as animal) Fischer344 4 No data oral: feed 24.0000000000 h yes not applicable Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo Equivalent or similar to OECD Guideline 489 Yes Acceptable House mouse (as animal) CD-1 4 No data oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo Equivalent or similar to OECD Guideline 489 Yes Acceptable House mouse (as animal) CD-1 4 No data oral: gavage 8.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo Equivalent or similar to OECD Guideline 489 Yes Acceptable House mouse (as animal) CD-1 4 No data oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo Equivalent or similar to OECD Guideline 489 Yes Acceptable House mouse (as animal) CD-1 4 No data oral: gavage 3.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo Equivalent or similar to OECD Guideline 489 Yes Acceptable House mouse (as animal) CD-1 4 No data oral: gavage 8.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo Equivalent or similar to OECD Guideline 489 Yes Acceptable House mouse (as animal) CD-1 4 No data oral: gavage 3.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo Equivalent or similar to OECD Guideline 489 Yes Acceptable House mouse (as animal) CD-1 4 No data oral: unspecified yes, concurrent vehicle not applicable Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo Equivalent or similar to OECD Guideline 489 Yes Acceptable House mouse (as animal) CD-1 4 No data oral: unspecified yes, concurrent vehicle not applicable Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo Equivalent or similar to OECD Guideline 489 Yes Acceptable House mouse (as animal) CD-1 4 No data oral: unspecified yes, concurrent vehicle not applicable Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo Equivalent or similar to OECD Guideline 489 Yes Acceptable House mouse (as animal) CD-1 4 No data oral: unspecified yes, concurrent vehicle not applicable Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo Equivalent or similar to OECD Guideline 489 Yes Acceptable House mouse (as animal) CD-1 4 No data oral: unspecified yes, concurrent vehicle not applicable Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo Equivalent or similar to OECD Guideline 489 Yes Acceptable House mouse (as animal) CD-1 4 No data oral: unspecified yes, concurrent vehicle not applicable Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo Equivalent or similar to OECD Guideline 489 Yes Acceptable House mouse (as animal) CD-1 4 No data oral: unspecified yes, concurrent vehicle not applicable Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is a metabolite of the substance Phenylhydroquinone 1079-21-6 2-phenylbenzene-1,4-diol Not in list C12H10O2 C1=CC=C(C=C1)C2=C(C=CC(=C2)O)O InChI=1S/C12H10O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8,13-14H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo Equivalent or similar to OECD Guideline 489 Yes Acceptable Rat (as animal) Fischer344 2 Male other 10.0000000000 min yes, concurrent vehicle not applicable Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is a metabolite of the substance Phenylbenzoquinone 363-03-1 2-phenylcyclohexa-2,5-diene-1,4-dione Not in list C12H8O2 C1=CC=C(C=C1)C2=CC(=O)C=CC2=O InChI=1S/C12H8O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo Equivalent or similar to OECD Guideline 489 Yes Acceptable Rat (as animal) Fischer344 2 Male other 10.0000000000 min yes, concurrent vehicle not applicable Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo Equivalent or similar to OECD Guideline 489 Yes Acceptable Rat (as animal) Fischer344 2 Male other 10.0000000000 min yes, concurrent vehicle not applicable Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is a metabolite of the substance Phenylbenzoquinone 363-03-1 2-phenylcyclohexa-2,5-diene-1,4-dione Not in list C12H8O2 C1=CC=C(C=C1)C2=CC(=O)C=CC2=O InChI=1S/C12H8O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo Equivalent or similar to OECD Guideline 489 Yes Acceptable Rat (as animal) Fischer344 2 Male/Female other 10.0000000000 min yes, concurrent vehicle not applicable Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo Equivalent or similar to OECD Guideline 489 Yes Acceptable Rat (as animal) Fischer344 2 Male/Female other 10.0000000000 min yes, concurrent vehicle not applicable Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is a metabolite of the substance Phenylhydroquinone 1079-21-6 2-phenylbenzene-1,4-diol Not in list C12H10O2 C1=CC=C(C=C1)C2=C(C=CC(=C2)O)O InChI=1S/C12H10O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8,13-14H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo Equivalent or similar to OECD Guideline 489 Yes Acceptable Rat (as animal) Fischer344 2 Male/Female other 10.0000000000 min yes, concurrent vehicle not applicable Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable Rat (as animal) Fischer344 4 Male oral: gavage 16.0000000000 h no data not applicable Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is part of a group assessment 2-Phenylphenol sodium salt 205-055-6 132-27-4 2-Phenylphenol sodium salt Not in list C12H9NaO C1=CC=C(C=C1)C2=CC=CC=C2[O-].[Na+] InChI=1S/C12H10O.Na/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10;/h1-9,13H;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable Rat (as animal) Fischer344 4 Male oral: gavage 16.0000000000 h no data not applicable Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is part of a group assessment 2-Phenylphenol sodium salt 205-055-6 132-27-4 2-Phenylphenol sodium salt Not in list C12H9NaO C1=CC=C(C=C1)C2=CC=CC=C2[O-].[Na+] InChI=1S/C12H10O.Na/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10;/h1-9,13H;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable Rat (as animal) Fischer344 4 Male oral: gavage 16.0000000000 h no data not applicable Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is part of a group assessment 2-Phenylphenol sodium salt 205-055-6 132-27-4 2-Phenylphenol sodium salt Not in list C12H9NaO C1=CC=C(C=C1)C2=CC=CC=C2[O-].[Na+] InChI=1S/C12H10O.Na/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10;/h1-9,13H;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable Rat (as animal) Fischer344 4 Male oral: gavage 16.0000000000 h no data not applicable Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable Rat (as animal) Fischer344 4 Male oral: gavage 16.0000000000 h no data not applicable Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Rat (as animal) hepatocytes Not reported no data no data Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable Rat (as animal) Fischer344 4 Male oral: gavage 16.0000000000 h no data not applicable Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable Rat (as animal) Fischer344 Male oral: gavage 24.0000000000 h yes not applicable Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable Rat (as animal) Fischer344 Male oral: gavage 24.0000000000 h yes not applicable Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable Rat (as animal) Fischer344 Male oral: gavage 24.0000000000 h yes not applicable Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable Rat (as animal) Fischer344 Male oral: gavage 24.0000000000 h yes not applicable Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) Yes Acceptable House mouse (as animal) C3H 15 Male oral: gavage yes not applicable Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is a metabolite of the substance Phenylbenzoquinone 363-03-1 2-phenylcyclohexa-2,5-diene-1,4-dione Not in list C12H8O2 C1=CC=C(C=C1)C2=CC(=O)C=CC2=O InChI=1S/C12H8O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8H organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data no data Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is a metabolite of the substance Phenylhydroquinone 1079-21-6 2-phenylbenzene-1,4-diol Not in list C12H10O2 C1=CC=C(C=C1)C2=C(C=CC(=C2)O)O InChI=1S/C12H10O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8,13-14H organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data no data Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is identical to the substance 2-Phenylphenol 201-993-5 90-43-7 2-Phenylphenol 2-phenylphenol C12H10O C1=CC=C(C=C1)C2=CC=CC=C2O InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Rat (as animal) hepatocytes Not reported no data no data Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+Aluminium sulphate 233-135-0 10043-01-3 single chemical entity Component is part of a group but not included in the group assessment Sodium aluminium sulphate 233-277-3 10102-71-3 aluminum;sodium;disulfate Aluminium ammonium sulphate AlNaO8S2 [O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Na+].[Al+3] InChI=1S/Al.Na.2H2O4S/c;;2*1-5(2,3)4/h;;2*(H2,1,2,3,4)/q+3;+1;;/p-4 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation yeast cytogenetic assay in vitro Equivalent or similar to OECD Guideline 480 (Genetic Toxicology: Saccharomyces cerevisiae, Gene Mutation Assay) Yes Acceptable Saccharomyces cerevisiae (as organism) Not reported Not reported no data no data Negative RMS: Spain Aluminium sulphate (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium sulfate 05Nov2010 2010 doi:10.2903/j.efsa.2010.1889
+Aluminium sulphate 233-135-0 10043-01-3 single chemical entity Component is part of a group but not included in the group assessment Sodium aluminium sulphate 233-277-3 10102-71-3 aluminum;sodium;disulfate Aluminium ammonium sulphate AlNaO8S2 [O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Na+].[Al+3] InChI=1S/Al.Na.2H2O4S/c;;2*1-5(2,3)4/h;;2*(H2,1,2,3,4)/q+3;+1;;/p-4 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data no data Negative RMS: Spain Aluminium sulphate (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium sulfate 05Nov2010 2010 doi:10.2903/j.efsa.2010.1889
+Aluminium sulphate 233-135-0 10043-01-3 single chemical entity Component is part of a group but not included in the group assessment Sodium aluminium sulphate 233-277-3 10102-71-3 aluminum;sodium;disulfate Aluminium ammonium sulphate AlNaO8S2 [O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Na+].[Al+3] InChI=1S/Al.Na.2H2O4S/c;;2*1-5(2,3)4/h;;2*(H2,1,2,3,4)/q+3;+1;;/p-4 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data no data Negative RMS: Spain Aluminium sulphate (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium sulfate 05Nov2010 2010 doi:10.2903/j.efsa.2010.1889
+Aluminium sulphate 233-135-0 10043-01-3 single chemical entity Component is part of a group but not included in the group assessment Sodium aluminium sulphate 233-277-3 10102-71-3 aluminum;sodium;disulfate Aluminium ammonium sulphate AlNaO8S2 [O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Na+].[Al+3] InChI=1S/Al.Na.2H2O4S/c;;2*1-5(2,3)4/h;;2*(H2,1,2,3,4)/q+3;+1;;/p-4 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data no data Negative RMS: Spain Aluminium sulphate (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium sulfate 05Nov2010 2010 doi:10.2903/j.efsa.2010.1889
+Aluminium sulphate 233-135-0 10043-01-3 single chemical entity Component is identical to the substance Aluminium sulphate 233-135-0 10043-01-3 Dialuminum trisulfate Aluminium sulphate Al2O12S3 [O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3].[Al+3] InChI=1S/2Al.3H2O4S/c;;3*1-5(2,3)4/h;;3*(H2,1,2,3,4)/q2*+3;;;/p-6 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported no data no data Negative RMS: Spain Aluminium sulphate (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium sulfate 05Nov2010 2010 doi:10.2903/j.efsa.2010.1889
+Aluminium sulphate 233-135-0 10043-01-3 single chemical entity Component is identical to the substance Aluminium sulphate 233-135-0 10043-01-3 Dialuminum trisulfate Aluminium sulphate Al2O12S3 [O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3].[Al+3] InChI=1S/2Al.3H2O4S/c;;3*1-5(2,3)4/h;;3*(H2,1,2,3,4)/q2*+3;;;/p-6 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported no data no data Negative RMS: Spain Aluminium sulphate (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium sulfate 05Nov2010 2010 doi:10.2903/j.efsa.2010.1889
+Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 single chemical entity Component is part of a group but not included in the group assessment Aluminium sulphate 233-135-0 10043-01-3 Dialuminum trisulfate Aluminium sulphate Al2O12S3 [O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3].[Al+3] InChI=1S/2Al.3H2O4S/c;;3*1-5(2,3)4/h;;3*(H2,1,2,3,4)/q2*+3;;;/p-6 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported no data no data Negative RMS: Portugal Aluminium ammonium sulphate (Final Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate) 15Mar2012 2012 doi:10.2903/j.efsa.2012.2491
+Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 single chemical entity Component is part of a group but not included in the group assessment Aluminium sulphate 233-135-0 10043-01-3 Dialuminum trisulfate Aluminium sulphate Al2O12S3 [O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3].[Al+3] InChI=1S/2Al.3H2O4S/c;;3*1-5(2,3)4/h;;3*(H2,1,2,3,4)/q2*+3;;;/p-6 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported no data no data Negative RMS: Portugal Aluminium ammonium sulphate (Final Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate) 15Mar2012 2012 doi:10.2903/j.efsa.2012.2491
+Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 single chemical entity Component is part of a group but not included in the group assessment Aluminium chloride 231-208-1 7446-70-0 trichloroalumane Not in list AlCl3 [Al](Cl)(Cl)Cl InChI=1S/Al.3ClH/h;3*1H/q+3;;;/p-3 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported no data no data Negative RMS: Portugal Aluminium ammonium sulphate (Final Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate) 15Mar2012 2012 doi:10.2903/j.efsa.2012.2491
+Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 single chemical entity Component is part of a group but not included in the group assessment Aluminium oxide 618-619-5 1344-28-1 dialuminum;oxygen(2-) Not in list Al2O3 [O-2].[O-2].[O-2].[Al+3].[Al+3] InChI=1S/2Al.3O/q2*+3;3*-2 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported no data no data Negative RMS: Portugal Aluminium ammonium sulphate (Final Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate) 15Mar2012 2012 doi:10.2903/j.efsa.2012.2491
+Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 single chemical entity Component is part of a group but not included in the group assessment Aluminium oxide 618-619-5 1344-28-1 dialuminum;oxygen(2-) Not in list Al2O3 [O-2].[O-2].[O-2].[Al+3].[Al+3] InChI=1S/2Al.3O/q2*+3;3*-2 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported no data no data Negative RMS: Portugal Aluminium ammonium sulphate (Final Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate) 15Mar2012 2012 doi:10.2903/j.efsa.2012.2491
+Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 single chemical entity Component is part of a group but not included in the group assessment Aluminium chloride 231-208-1 7446-70-0 trichloroalumane Not in list AlCl3 [Al](Cl)(Cl)Cl InChI=1S/Al.3ClH/h;3*1H/q+3;;;/p-3 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported no data no data Negative RMS: Portugal Aluminium ammonium sulphate (Final Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate) 15Mar2012 2012 doi:10.2903/j.efsa.2012.2491
+Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 single chemical entity Component is part of a group but not included in the group assessment Aluminium chloride 231-208-1 7446-70-0 trichloroalumane Not in list AlCl3 [Al](Cl)(Cl)Cl InChI=1S/Al.3ClH/h;3*1H/q+3;;;/p-3 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported no data no data Negative RMS: Portugal Aluminium ammonium sulphate (Final Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate) 15Mar2012 2012 doi:10.2903/j.efsa.2012.2491
+Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 single chemical entity Component is part of a group but not included in the group assessment Aluminium sulphate 233-135-0 10043-01-3 Dialuminum trisulfate Aluminium sulphate Al2O12S3 [O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3].[Al+3] InChI=1S/2Al.3H2O4S/c;;3*1-5(2,3)4/h;;3*(H2,1,2,3,4)/q2*+3;;;/p-6 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported no data no data Negative RMS: Portugal Aluminium ammonium sulphate (Final Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate) 15Mar2012 2012 doi:10.2903/j.efsa.2012.2491
+Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 single chemical entity Component is part of a group but not included in the group assessment Aluminium chloride 231-208-1 7446-70-0 trichloroalumane Not in list AlCl3 [Al](Cl)(Cl)Cl InChI=1S/Al.3ClH/h;3*1H/q+3;;;/p-3 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported no data no data Negative RMS: Portugal Aluminium ammonium sulphate (Final Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate) 15Mar2012 2012 doi:10.2903/j.efsa.2012.2491
+Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 single chemical entity Component is part of a group but not included in the group assessment Aluminium sulphate 233-135-0 10043-01-3 Dialuminum trisulfate Aluminium sulphate Al2O12S3 [O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3].[Al+3] InChI=1S/2Al.3H2O4S/c;;3*1-5(2,3)4/h;;3*(H2,1,2,3,4)/q2*+3;;;/p-6 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported no data no data Negative RMS: Portugal Aluminium ammonium sulphate (Final Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate) 15Mar2012 2012 doi:10.2903/j.efsa.2012.2491
+Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 single chemical entity Component is part of a group but not included in the group assessment Aluminium oxide 618-619-5 1344-28-1 dialuminum;oxygen(2-) Not in list Al2O3 [O-2].[O-2].[O-2].[Al+3].[Al+3] InChI=1S/2Al.3O/q2*+3;3*-2 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported no data no data Negative RMS: Portugal Aluminium ammonium sulphate (Final Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate) 15Mar2012 2012 doi:10.2903/j.efsa.2012.2491
+Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 single chemical entity Component is part of a group but not included in the group assessment Aluminium oxide 618-619-5 1344-28-1 dialuminum;oxygen(2-) Not in list Al2O3 [O-2].[O-2].[O-2].[Al+3].[Al+3] InChI=1S/2Al.3O/q2*+3;3*-2 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported no data no data Negative RMS: Portugal Aluminium ammonium sulphate (Final Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate) 15Mar2012 2012 doi:10.2903/j.efsa.2012.2491
+Aluminium sulphate 233-135-0 10043-01-3 single chemical entity Component is identical to the substance Aluminium sulphate 233-135-0 10043-01-3 Dialuminum trisulfate Aluminium sulphate Al2O12S3 [O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3].[Al+3] InChI=1S/2Al.3H2O4S/c;;3*1-5(2,3)4/h;;3*(H2,1,2,3,4)/q2*+3;;;/p-6 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported no data no data Negative RMS: Spain Aluminium sulphate (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium sulfate 05Nov2010 2010 doi:10.2903/j.efsa.2010.1889
+Aluminium sulphate 233-135-0 10043-01-3 single chemical entity Component is identical to the substance Aluminium sulphate 233-135-0 10043-01-3 Dialuminum trisulfate Aluminium sulphate Al2O12S3 [O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3].[Al+3] InChI=1S/2Al.3H2O4S/c;;3*1-5(2,3)4/h;;3*(H2,1,2,3,4)/q2*+3;;;/p-6 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported no data no data Negative RMS: Spain Aluminium sulphate (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium sulfate 05Nov2010 2010 doi:10.2903/j.efsa.2010.1889
+Aluminium sulphate 233-135-0 10043-01-3 single chemical entity Component is identical to the substance Aluminium sulphate 233-135-0 10043-01-3 Dialuminum trisulfate Aluminium sulphate Al2O12S3 [O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3].[Al+3] InChI=1S/2Al.3H2O4S/c;;3*1-5(2,3)4/h;;3*(H2,1,2,3,4)/q2*+3;;;/p-6 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Hamster (as animal) embryo cells Not reported no data no data Negative RMS: Spain Aluminium sulphate (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium sulfate 05Nov2010 2010 doi:10.2903/j.efsa.2010.1889
+Aluminium sulphate 233-135-0 10043-01-3 single chemical entity Component is identical to the substance Aluminium sulphate 233-135-0 10043-01-3 Dialuminum trisulfate Aluminium sulphate Al2O12S3 [O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3].[Al+3] InChI=1S/2Al.3H2O4S/c;;3*1-5(2,3)4/h;;3*(H2,1,2,3,4)/q2*+3;;;/p-6 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable Human (as organism) 10 Male/Female Not reported yes not applicable Positive RMS: Spain Aluminium sulphate (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium sulfate 05Nov2010 2010 doi:10.2903/j.efsa.2010.1889
+Aluminium sulphate 233-135-0 10043-01-3 single chemical entity Component is identical to the substance Aluminium sulphate 233-135-0 10043-01-3 Dialuminum trisulfate Aluminium sulphate Al2O12S3 [O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3].[Al+3] InChI=1S/2Al.3H2O4S/c;;3*1-5(2,3)4/h;;3*(H2,1,2,3,4)/q2*+3;;;/p-6 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No data Acceptable Human (as organism) lymphocytes 10 Male/Female Not reported yes no data Positive RMS: Spain Aluminium sulphate (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium sulfate 05Nov2010 2010 doi:10.2903/j.efsa.2010.1889
+Aluminium sulphate 233-135-0 10043-01-3 single chemical entity Component is identical to the substance Aluminium sulphate 233-135-0 10043-01-3 Dialuminum trisulfate Aluminium sulphate Al2O12S3 [O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3].[Al+3] InChI=1S/2Al.3H2O4S/c;;3*1-5(2,3)4/h;;3*(H2,1,2,3,4)/q2*+3;;;/p-6 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No data Acceptable Human (as organism) lymphocytes 10 Male/Female Not reported yes no data Positive RMS: Spain Aluminium sulphate (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium sulfate 05Nov2010 2010 doi:10.2903/j.efsa.2010.1889
+Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 single chemical entity Component is part of a group but not included in the group assessment Aluminium sulphate 233-135-0 10043-01-3 Dialuminum trisulfate Aluminium sulphate Al2O12S3 [O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3].[Al+3] InChI=1S/2Al.3H2O4S/c;;3*1-5(2,3)4/h;;3*(H2,1,2,3,4)/q2*+3;;;/p-6 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No data Acceptable Human (as organism) Not reported no data no data Positive RMS: Portugal Aluminium ammonium sulphate (Final Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate) 15Mar2012 2012 doi:10.2903/j.efsa.2012.2491
+Aluminium sulphate 233-135-0 10043-01-3 single chemical entity Component is identical to the substance Aluminium sulphate 233-135-0 10043-01-3 Dialuminum trisulfate Aluminium sulphate Al2O12S3 [O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3].[Al+3] InChI=1S/2Al.3H2O4S/c;;3*1-5(2,3)4/h;;3*(H2,1,2,3,4)/q2*+3;;;/p-6 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) Swiss 2 No data intraperitoneal 24.0000000000 h yes not applicable Positive RMS: Spain Aluminium sulphate (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium sulfate 05Nov2010 2010 doi:10.2903/j.efsa.2010.1889
+Aluminium sulphate 233-135-0 10043-01-3 single chemical entity Component is identical to the substance Aluminium sulphate 233-135-0 10043-01-3 Dialuminum trisulfate Aluminium sulphate Al2O12S3 [O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3].[Al+3] InChI=1S/2Al.3H2O4S/c;;3*1-5(2,3)4/h;;3*(H2,1,2,3,4)/q2*+3;;;/p-6 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) Swiss 6 No data intraperitoneal 24.0000000000 h yes not applicable Positive RMS: Spain Aluminium sulphate (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium sulfate 05Nov2010 2010 doi:10.2903/j.efsa.2010.1889
+Aluminium sulphate 233-135-0 10043-01-3 single chemical entity Component is identical to the substance Aluminium sulphate 233-135-0 10043-01-3 Dialuminum trisulfate Aluminium sulphate Al2O12S3 [O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3].[Al+3] InChI=1S/2Al.3H2O4S/c;;3*1-5(2,3)4/h;;3*(H2,1,2,3,4)/q2*+3;;;/p-6 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) Swiss 5 Male intraperitoneal 24.0000000000 h yes not applicable Positive RMS: Spain Aluminium sulphate (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium sulfate 05Nov2010 2010 doi:10.2903/j.efsa.2010.1889
+Aluminium sulphate 233-135-0 10043-01-3 single chemical entity Component is part of a group but not included in the group assessment Aluminium potassium sulphate 233-141-3 10043-67-1 aluminum;potassium;disulfate Aluminium potassium sulphate AlKO8S2 [O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3].[K+] InChI=1S/Al.K.2H2O4S/c;;2*1-5(2,3)4/h;;2*(H2,1,2,3,4)/q+3;+1;;/p-4 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No data Acceptable Rat (as animal) Not reported Male oral: unspecified 24.0000000000 h yes not applicable Positive RMS: Spain Aluminium sulphate (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium sulfate 05Nov2010 2010 doi:10.2903/j.efsa.2010.1889
+Aluminium sulphate 233-135-0 10043-01-3 single chemical entity Component is identical to the substance Aluminium sulphate 233-135-0 10043-01-3 Dialuminum trisulfate Aluminium sulphate Al2O12S3 [O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3].[Al+3] InChI=1S/2Al.3H2O4S/c;;3*1-5(2,3)4/h;;3*(H2,1,2,3,4)/q2*+3;;;/p-6 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No data Acceptable Rat (as animal) Not reported Male oral: unspecified 24.0000000000 h yes not applicable Positive RMS: Spain Aluminium sulphate (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium sulfate 05Nov2010 2010 doi:10.2903/j.efsa.2010.1889
+Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 single chemical entity Component is part of a group but not included in the group assessment Aluminium potassium sulphate 233-141-3 10043-67-1 aluminum;potassium;disulfate Aluminium potassium sulphate AlKO8S2 [O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3].[K+] InChI=1S/Al.K.2H2O4S/c;;2*1-5(2,3)4/h;;2*(H2,1,2,3,4)/q+3;+1;;/p-4 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No data Acceptable Rat (as animal) Not reported Male oral: unspecified 24.0000000000 h yes not applicable Positive RMS: Portugal Aluminium ammonium sulphate (Final Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate) 15Mar2012 2012 doi:10.2903/j.efsa.2012.2491
+Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 single chemical entity Component is part of a group but not included in the group assessment Aluminium sulphate 233-135-0 10043-01-3 Dialuminum trisulfate Aluminium sulphate Al2O12S3 [O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3].[Al+3] InChI=1S/2Al.3H2O4S/c;;3*1-5(2,3)4/h;;3*(H2,1,2,3,4)/q2*+3;;;/p-6 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No data Acceptable Rat (as animal) Not reported Male oral: unspecified 24.0000000000 h yes not applicable Positive RMS: Portugal Aluminium ammonium sulphate (Final Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate) 15Mar2012 2012 doi:10.2903/j.efsa.2012.2491
+Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 single chemical entity Component is part of a group but not included in the group assessment Aluminum 231-072-3 7429-90-5 Aluminum Aluminum (Al) Al [Al] InChI=1S/Al metal compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No data Acceptable Human (as organism) astrocytes cell Not reported no data no data Positive RMS: Portugal Aluminium ammonium sulphate (Final Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate) 15Mar2012 2012 doi:10.2903/j.efsa.2012.2491
+Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 single chemical entity Component is part of a group but not included in the group assessment Aluminum 231-072-3 7429-90-5 Aluminum Aluminum (Al) Al [Al] InChI=1S/Al metal compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No data Acceptable Human (as organism) lymphocytes Not reported no data no data Positive RMS: Portugal Aluminium ammonium sulphate (Final Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate) 15Mar2012 2012 doi:10.2903/j.efsa.2012.2491
+Aluminium sulphate 233-135-0 10043-01-3 single chemical entity Component is part of a group but not included in the group assessment Aluminum 231-072-3 7429-90-5 Aluminum Aluminum (Al) Al [Al] InChI=1S/Al metal compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Human (as organism) astrocytes cell Not reported no data no data Positive RMS: Spain Aluminium sulphate (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium sulfate 05Nov2010 2010 doi:10.2903/j.efsa.2010.1889
+Gibberellins 201-001-0 77-06-5 complex product: derived from botanical sources Component is identical to the substance Gibberellins 201-001-0 77-06-5 2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid Not in list C19H22O6 CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: Hungary Gibberellins - GA4/GA7 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline) 10Jan2012 2012 doi:10.2903/j.efsa.2012.2502
+Gibberellins 201-001-0 77-06-5 complex product: derived from botanical sources Component is identical to the substance Gibberellins 201-001-0 77-06-5 2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid Not in list C19H22O6 CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Hungary Gibberellins - GA4/GA7 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline) 10Jan2012 2012 doi:10.2903/j.efsa.2012.2502
+Gibberellins 201-001-0 77-06-5 complex product: derived from botanical sources Component is identical to the substance Gibberellins 201-001-0 77-06-5 2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid Not in list C19H22O6 CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: Hungary Gibberellins - GA4/GA7 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline) 10Jan2012 2012 doi:10.2903/j.efsa.2012.2502
+Gibberellins 201-001-0 77-06-5 complex product: derived from botanical sources Component is identical to the substance Gibberellins 201-001-0 77-06-5 2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid Not in list C19H22O6 CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Hungary Gibberellins - GA4/GA7 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline) 10Jan2012 2012 doi:10.2903/j.efsa.2012.2502
+Gibberellins 201-001-0 77-06-5 complex product: derived from botanical sources Component is identical to the substance Gibberellins 201-001-0 77-06-5 2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid Not in list C19H22O6 CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Hungary Gibberellins - GA4/GA7 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline) 10Jan2012 2012 doi:10.2903/j.efsa.2012.2502
+Gibberellins 201-001-0 77-06-5 complex product: derived from botanical sources Component is identical to the substance Gibberellins 201-001-0 77-06-5 2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid Not in list C19H22O6 CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Hungary Gibberellins - GA4/GA7 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline) 10Jan2012 2012 doi:10.2903/j.efsa.2012.2502
+Gibberellins 201-001-0 77-06-5 complex product: derived from botanical sources Component is identical to the substance Gibberellins 201-001-0 77-06-5 2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid Not in list C19H22O6 CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Hungary Gibberellins - GA4/GA7 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline) 10Jan2012 2012 doi:10.2903/j.efsa.2012.2502
+Gibberellins 201-001-0 77-06-5 complex product: derived from botanical sources Component is identical to the substance Gibberellins 201-001-0 77-06-5 2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid Not in list C19H22O6 CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Hungary Gibberellins - GA4/GA7 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline) 10Jan2012 2012 doi:10.2903/j.efsa.2012.2502
+Gibberellins 201-001-0 77-06-5 complex product: derived from botanical sources Component is identical to the substance Gibberellins 201-001-0 77-06-5 2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid Not in list C19H22O6 CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Hungary Gibberellins - GA4/GA7 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline) 10Jan2012 2012 doi:10.2903/j.efsa.2012.2502
+Gibberellins 201-001-0 77-06-5 complex product: derived from botanical sources Component is identical to the substance Gibberellins 201-001-0 77-06-5 2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid Not in list C19H22O6 CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Hungary Gibberellins - GA4/GA7 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline) 10Jan2012 2012 doi:10.2903/j.efsa.2012.2502
+Gibberellins 201-001-0 77-06-5 complex product: derived from botanical sources Component is identical to the substance Gibberellins 201-001-0 77-06-5 2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid Not in list C19H22O6 CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: Hungary Gibberellins - GA4/GA7 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline) 10Jan2012 2012 doi:10.2903/j.efsa.2012.2502
+Gibberellins 201-001-0 77-06-5 complex product: derived from botanical sources Component is identical to the substance Gibberellins 201-001-0 77-06-5 2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid Not in list C19H22O6 CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Hungary Gibberellins - GA4/GA7 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline) 10Jan2012 2012 doi:10.2903/j.efsa.2012.2502
+Gibberellins 201-001-0 77-06-5 complex product: derived from botanical sources Component is identical to the substance Gibberellins 201-001-0 77-06-5 2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid Not in list C19H22O6 CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Hungary Gibberellins - GA4/GA7 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline) 10Jan2012 2012 doi:10.2903/j.efsa.2012.2502
+Gibberellins 201-001-0 77-06-5 complex product: derived from botanical sources Component is identical to the substance Gibberellins 201-001-0 77-06-5 2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid Not in list C19H22O6 CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Hungary Gibberellins - GA4/GA7 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline) 10Jan2012 2012 doi:10.2903/j.efsa.2012.2502
+Gibberellins 201-001-0 77-06-5 complex product: derived from botanical sources Component is identical to the substance Gibberellins 201-001-0 77-06-5 2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid Not in list C19H22O6 CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: Hungary Gibberellins - GA4/GA7 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline) 10Jan2012 2012 doi:10.2903/j.efsa.2012.2502
+Gibberellins 201-001-0 77-06-5 complex product: derived from botanical sources Component is identical to the substance Gibberellins 201-001-0 77-06-5 2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid Not in list C19H22O6 CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Hungary Gibberellins - GA4/GA7 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline) 10Jan2012 2012 doi:10.2903/j.efsa.2012.2502
+Gibberellins 201-001-0 77-06-5 complex product: derived from botanical sources Component is identical to the substance Gibberellins 201-001-0 77-06-5 2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid Not in list C19H22O6 CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Hungary Gibberellins - GA4/GA7 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline) 10Jan2012 2012 doi:10.2903/j.efsa.2012.2502
+Gibberellins 201-001-0 77-06-5 complex product: derived from botanical sources Component is identical to the substance Gibberellins 201-001-0 77-06-5 2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid Not in list C19H22O6 CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Hungary Gibberellins - GA4/GA7 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline) 10Jan2012 2012 doi:10.2903/j.efsa.2012.2502
+Gibberellins 201-001-0 77-06-5 complex product: derived from botanical sources Component is identical to the substance Gibberellins 201-001-0 77-06-5 2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid Not in list C19H22O6 CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Hungary Gibberellins - GA4/GA7 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline) 10Jan2012 2012 doi:10.2903/j.efsa.2012.2502
+Gibberellins 201-001-0 77-06-5 complex product: derived from botanical sources Component is identical to the substance Gibberellins 201-001-0 77-06-5 2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid Not in list C19H22O6 CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Hungary Gibberellins - GA4/GA7 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline) 10Jan2012 2012 doi:10.2903/j.efsa.2012.2502
+Gibberellins 201-001-0 77-06-5 complex product: derived from botanical sources Component is identical to the substance Gibberellins 201-001-0 77-06-5 2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid Not in list C19H22O6 CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Positive RMS: Hungary Gibberellins - GA4/GA7 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline) 10Jan2012 2012 doi:10.2903/j.efsa.2012.2502
+Gibberellins 201-001-0 77-06-5 complex product: derived from botanical sources Component is identical to the substance Gibberellins 201-001-0 77-06-5 2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid Not in list C19H22O6 CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Positive RMS: Hungary Gibberellins - GA4/GA7 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline) 10Jan2012 2012 doi:10.2903/j.efsa.2012.2502
+Gibberellins 201-001-0 77-06-5 complex product: derived from botanical sources Component is identical to the substance Gibberellins 201-001-0 77-06-5 2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid Not in list C19H22O6 CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes without Positive RMS: Hungary Gibberellins - GA4/GA7 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline) 10Jan2012 2012 doi:10.2903/j.efsa.2012.2502
+Gibberellins 201-001-0 77-06-5 complex product: derived from botanical sources Component is identical to the substance Gibberellins 201-001-0 77-06-5 2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid Not in list C19H22O6 CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: Hungary Gibberellins - GA4/GA7 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline) 10Jan2012 2012 doi:10.2903/j.efsa.2012.2502
+Gibberellins 201-001-0 77-06-5 complex product: derived from botanical sources Component is identical to the substance Gibberellins 201-001-0 77-06-5 2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid Not in list C19H22O6 CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Hungary Gibberellins - GA4/GA7 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline) 10Jan2012 2012 doi:10.2903/j.efsa.2012.2502
+Gibberellins 201-001-0 77-06-5 complex product: derived from botanical sources Component is identical to the substance Gibberellins 201-001-0 77-06-5 2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid Not in list C19H22O6 CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Hungary Gibberellins - GA4/GA7 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline) 10Jan2012 2012 doi:10.2903/j.efsa.2012.2502
+Gibberellins 201-001-0 77-06-5 complex product: derived from botanical sources Component is identical to the substance Gibberellins 201-001-0 77-06-5 2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid Not in list C19H22O6 CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Hungary Gibberellins - GA4/GA7 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline) 10Jan2012 2012 doi:10.2903/j.efsa.2012.2502
+Gibberellins 201-001-0 77-06-5 complex product: derived from botanical sources Component is identical to the substance Gibberellins 201-001-0 77-06-5 2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid Not in list C19H22O6 CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Hungary Gibberellins - GA4/GA7 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline) 10Jan2012 2012 doi:10.2903/j.efsa.2012.2502
+Gibberellins 201-001-0 77-06-5 complex product: derived from botanical sources Component is identical to the substance Gibberellins 201-001-0 77-06-5 2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid Not in list C19H22O6 CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Hungary Gibberellins - GA4/GA7 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline) 10Jan2012 2012 doi:10.2903/j.efsa.2012.2502
+Gibberellins 201-001-0 77-06-5 complex product: derived from botanical sources Component is identical to the substance Gibberellins 201-001-0 77-06-5 2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid Not in list C19H22O6 CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Hungary Gibberellins - GA4/GA7 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline) 10Jan2012 2012 doi:10.2903/j.efsa.2012.2502
+Gibberellins 201-001-0 77-06-5 complex product: derived from botanical sources Component is identical to the substance Gibberellins 201-001-0 77-06-5 2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid Not in list C19H22O6 CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) ICR 10 Male/Female intraperitoneal 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Hungary Gibberellins - GA4/GA7 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline) 10Jan2012 2012 doi:10.2903/j.efsa.2012.2502
+Gibberellins 201-001-0 77-06-5 complex product: derived from botanical sources Component is identical to the substance Gibberellins 201-001-0 77-06-5 2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid Not in list C19H22O6 CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) ICR 10 Male/Female intraperitoneal 72.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Hungary Gibberellins - GA4/GA7 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline) 10Jan2012 2012 doi:10.2903/j.efsa.2012.2502
+Gibberellins 201-001-0 77-06-5 complex product: derived from botanical sources Component is identical to the substance Gibberellins 201-001-0 77-06-5 2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid Not in list C19H22O6 CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) ICR 10 Male/Female intraperitoneal 24.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity RMS: Hungary Gibberellins - GA4/GA7 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline) 10Jan2012 2012 doi:10.2903/j.efsa.2012.2502
+Gibberellins 201-001-0 77-06-5 complex product: derived from botanical sources Component is identical to the substance Gibberellins 201-001-0 77-06-5 2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid Not in list C19H22O6 CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes without Negative RMS: Hungary Gibberellins - GA4/GA7 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline) 10Jan2012 2012 doi:10.2903/j.efsa.2012.2502
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Copper oxychloride copper;chloro hypochlorite Not in list Cl2CuO+2 O(Cl)Cl.[Cu+2] InChI=1S/Cl2O.Cu/c1-3-2;/q;+2 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Copper oxychloride copper;chloro hypochlorite Not in list Cl2CuO+2 O(Cl)Cl.[Cu+2] InChI=1S/Cl2O.Cu/c1-3-2;/q;+2 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Copper oxychloride copper;chloro hypochlorite Not in list Cl2CuO+2 O(Cl)Cl.[Cu+2] InChI=1S/Cl2O.Cu/c1-3-2;/q;+2 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Copper oxychloride copper;chloro hypochlorite Not in list Cl2CuO+2 O(Cl)Cl.[Cu+2] InChI=1S/Cl2O.Cu/c1-3-2;/q;+2 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Copper oxychloride copper;chloro hypochlorite Not in list Cl2CuO+2 O(Cl)Cl.[Cu+2] InChI=1S/Cl2O.Cu/c1-3-2;/q;+2 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Copper oxychloride copper;chloro hypochlorite Not in list Cl2CuO+2 O(Cl)Cl.[Cu+2] InChI=1S/Cl2O.Cu/c1-3-2;/q;+2 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Copper oxychloride copper;chloro hypochlorite Not in list Cl2CuO+2 O(Cl)Cl.[Cu+2] InChI=1S/Cl2O.Cu/c1-3-2;/q;+2 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Positive RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Copper oxychloride copper;chloro hypochlorite Not in list Cl2CuO+2 O(Cl)Cl.[Cu+2] InChI=1S/Cl2O.Cu/c1-3-2;/q;+2 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Copper oxychloride copper;chloro hypochlorite Not in list Cl2CuO+2 O(Cl)Cl.[Cu+2] InChI=1S/Cl2O.Cu/c1-3-2;/q;+2 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Copper oxychloride copper;chloro hypochlorite Not in list Cl2CuO+2 O(Cl)Cl.[Cu+2] InChI=1S/Cl2O.Cu/c1-3-2;/q;+2 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Bordeaux mixture 1333-22-8 tetracopper;hexahydroxide;sulfate Not in list Cu4H6O10S [OH-].[OH-].[OH-].[OH-].[OH-].[OH-].[O-]S(=O)(=O)[O-].[Cu+2].[Cu+2].[Cu+2].[Cu+2] InChI=1S/4Cu.H2O4S.6H2O/c;;;;1-5(2,3)4;;;;;;/h;;;;(H2,1,2,3,4);6*1H2/q4*+2;;;;;;;/p-8 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Bordeaux mixture 1333-22-8 tetracopper;hexahydroxide;sulfate Not in list Cu4H6O10S [OH-].[OH-].[OH-].[OH-].[OH-].[OH-].[O-]S(=O)(=O)[O-].[Cu+2].[Cu+2].[Cu+2].[Cu+2] InChI=1S/4Cu.H2O4S.6H2O/c;;;;1-5(2,3)4;;;;;;/h;;;;(H2,1,2,3,4);6*1H2/q4*+2;;;;;;;/p-8 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Bordeaux mixture 1333-22-8 tetracopper;hexahydroxide;sulfate Not in list Cu4H6O10S [OH-].[OH-].[OH-].[OH-].[OH-].[OH-].[O-]S(=O)(=O)[O-].[Cu+2].[Cu+2].[Cu+2].[Cu+2] InChI=1S/4Cu.H2O4S.6H2O/c;;;;1-5(2,3)4;;;;;;/h;;;;(H2,1,2,3,4);6*1H2/q4*+2;;;;;;;/p-8 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Bordeaux mixture 1333-22-8 tetracopper;hexahydroxide;sulfate Not in list Cu4H6O10S [OH-].[OH-].[OH-].[OH-].[OH-].[OH-].[O-]S(=O)(=O)[O-].[Cu+2].[Cu+2].[Cu+2].[Cu+2] InChI=1S/4Cu.H2O4S.6H2O/c;;;;1-5(2,3)4;;;;;;/h;;;;(H2,1,2,3,4);6*1H2/q4*+2;;;;;;;/p-8 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Bordeaux mixture 1333-22-8 tetracopper;hexahydroxide;sulfate Not in list Cu4H6O10S [OH-].[OH-].[OH-].[OH-].[OH-].[OH-].[O-]S(=O)(=O)[O-].[Cu+2].[Cu+2].[Cu+2].[Cu+2] InChI=1S/4Cu.H2O4S.6H2O/c;;;;1-5(2,3)4;;;;;;/h;;;;(H2,1,2,3,4);6*1H2/q4*+2;;;;;;;/p-8 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Bordeaux mixture 1333-22-8 tetracopper;hexahydroxide;sulfate Not in list Cu4H6O10S [OH-].[OH-].[OH-].[OH-].[OH-].[OH-].[O-]S(=O)(=O)[O-].[Cu+2].[Cu+2].[Cu+2].[Cu+2] InChI=1S/4Cu.H2O4S.6H2O/c;;;;1-5(2,3)4;;;;;;/h;;;;(H2,1,2,3,4);6*1H2/q4*+2;;;;;;;/p-8 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Bordeaux mixture 1333-22-8 tetracopper;hexahydroxide;sulfate Not in list Cu4H6O10S [OH-].[OH-].[OH-].[OH-].[OH-].[OH-].[O-]S(=O)(=O)[O-].[Cu+2].[Cu+2].[Cu+2].[Cu+2] InChI=1S/4Cu.H2O4S.6H2O/c;;;;1-5(2,3)4;;;;;;/h;;;;(H2,1,2,3,4);6*1H2/q4*+2;;;;;;;/p-8 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Bordeaux mixture 1333-22-8 tetracopper;hexahydroxide;sulfate Not in list Cu4H6O10S [OH-].[OH-].[OH-].[OH-].[OH-].[OH-].[O-]S(=O)(=O)[O-].[Cu+2].[Cu+2].[Cu+2].[Cu+2] InChI=1S/4Cu.H2O4S.6H2O/c;;;;1-5(2,3)4;;;;;;/h;;;;(H2,1,2,3,4);6*1H2/q4*+2;;;;;;;/p-8 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Positive RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Bordeaux mixture 1333-22-8 tetracopper;hexahydroxide;sulfate Not in list Cu4H6O10S [OH-].[OH-].[OH-].[OH-].[OH-].[OH-].[O-]S(=O)(=O)[O-].[Cu+2].[Cu+2].[Cu+2].[Cu+2] InChI=1S/4Cu.H2O4S.6H2O/c;;;;1-5(2,3)4;;;;;;/h;;;;(H2,1,2,3,4);6*1H2/q4*+2;;;;;;;/p-8 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Bordeaux mixture 1333-22-8 tetracopper;hexahydroxide;sulfate Not in list Cu4H6O10S [OH-].[OH-].[OH-].[OH-].[OH-].[OH-].[O-]S(=O)(=O)[O-].[Cu+2].[Cu+2].[Cu+2].[Cu+2] InChI=1S/4Cu.H2O4S.6H2O/c;;;;1-5(2,3)4;;;;;;/h;;;;(H2,1,2,3,4);6*1H2/q4*+2;;;;;;;/p-8 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Copper (I) oxide 215-270-7 1317-39-1 Copper;hydrate Not in list Cu2H2O O.[Cu].[Cu] InChI=1S/2Cu.H2O/h;;1H2 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Copper (I) oxide 215-270-7 1317-39-1 Copper;hydrate Not in list Cu2H2O O.[Cu].[Cu] InChI=1S/2Cu.H2O/h;;1H2 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Copper (I) oxide 215-270-7 1317-39-1 Copper;hydrate Not in list Cu2H2O O.[Cu].[Cu] InChI=1S/2Cu.H2O/h;;1H2 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Copper (I) oxide 215-270-7 1317-39-1 Copper;hydrate Not in list Cu2H2O O.[Cu].[Cu] InChI=1S/2Cu.H2O/h;;1H2 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Copper II sulphate pentahydrate 616-477-9 7758-99-8 copper;sulfate;pentahydrate Not in list CuSO4.5H2O O.O.O.O.O.[O-]S(=O)(=O)[O-].[Cu+2] InChI=1S/Cu.H2O4S.5H2O/c;1-5(2,3)4;;;;;/h;(H2,1,2,3,4);5*1H2/q+2;;;;;;/p-2 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Copper II sulphate pentahydrate 616-477-9 7758-99-8 copper;sulfate;pentahydrate Not in list CuSO4.5H2O O.O.O.O.O.[O-]S(=O)(=O)[O-].[Cu+2] InChI=1S/Cu.H2O4S.5H2O/c;1-5(2,3)4;;;;;/h;(H2,1,2,3,4);5*1H2/q+2;;;;;;/p-2 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Copper II sulphate pentahydrate 616-477-9 7758-99-8 copper;sulfate;pentahydrate Not in list CuSO4.5H2O O.O.O.O.O.[O-]S(=O)(=O)[O-].[Cu+2] InChI=1S/Cu.H2O4S.5H2O/c;1-5(2,3)4;;;;;/h;(H2,1,2,3,4);5*1H2/q+2;;;;;;/p-2 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Copper II sulphate pentahydrate 616-477-9 7758-99-8 copper;sulfate;pentahydrate Not in list CuSO4.5H2O O.O.O.O.O.[O-]S(=O)(=O)[O-].[Cu+2] InChI=1S/Cu.H2O4S.5H2O/c;1-5(2,3)4;;;;;/h;(H2,1,2,3,4);5*1H2/q+2;;;;;;/p-2 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Copper II sulphate pentahydrate 616-477-9 7758-99-8 copper;sulfate;pentahydrate Not in list CuSO4.5H2O O.O.O.O.O.[O-]S(=O)(=O)[O-].[Cu+2] InChI=1S/Cu.H2O4S.5H2O/c;1-5(2,3)4;;;;;/h;(H2,1,2,3,4);5*1H2/q+2;;;;;;/p-2 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Copper II sulphate pentahydrate 616-477-9 7758-99-8 copper;sulfate;pentahydrate Not in list CuSO4.5H2O O.O.O.O.O.[O-]S(=O)(=O)[O-].[Cu+2] InChI=1S/Cu.H2O4S.5H2O/c;1-5(2,3)4;;;;;/h;(H2,1,2,3,4);5*1H2/q+2;;;;;;/p-2 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Copper II sulphate pentahydrate 616-477-9 7758-99-8 copper;sulfate;pentahydrate Not in list CuSO4.5H2O O.O.O.O.O.[O-]S(=O)(=O)[O-].[Cu+2] InChI=1S/Cu.H2O4S.5H2O/c;1-5(2,3)4;;;;;/h;(H2,1,2,3,4);5*1H2/q+2;;;;;;/p-2 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Copper II sulphate pentahydrate 616-477-9 7758-99-8 copper;sulfate;pentahydrate Not in list CuSO4.5H2O O.O.O.O.O.[O-]S(=O)(=O)[O-].[Cu+2] InChI=1S/Cu.H2O4S.5H2O/c;1-5(2,3)4;;;;;/h;(H2,1,2,3,4);5*1H2/q+2;;;;;;/p-2 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Copper II sulphate pentahydrate 616-477-9 7758-99-8 copper;sulfate;pentahydrate Not in list CuSO4.5H2O O.O.O.O.O.[O-]S(=O)(=O)[O-].[Cu+2] InChI=1S/Cu.H2O4S.5H2O/c;1-5(2,3)4;;;;;/h;(H2,1,2,3,4);5*1H2/q+2;;;;;;/p-2 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Copper II sulphate pentahydrate 616-477-9 7758-99-8 copper;sulfate;pentahydrate Not in list CuSO4.5H2O O.O.O.O.O.[O-]S(=O)(=O)[O-].[Cu+2] InChI=1S/Cu.H2O4S.5H2O/c;1-5(2,3)4;;;;;/h;(H2,1,2,3,4);5*1H2/q+2;;;;;;/p-2 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Tribasic copper sulfate 215-582-3 1333-22-8 Tricopper;dihydroxide;disulfate Tribasic copper sulfate Cu3H2O10S2 [OH-].[OH-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Cu+2].[Cu+2].[Cu+2] InChI=1S/3Cu.2H2O4S.2H2O/c;;;2*1-5(2,3)4;;/h;;;2*(H2,1,2,3,4);2*1H2/q3*+2;;;;/p-6 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Oxine copper 233-841-9 10380-28-6 copper;quinolin-8-olate Not in list C18H12CuN2O2 C1=CC2=C(C(=C1)[O-])N=CC=C2.C1=CC2=C(C(=C1)[O-])N=CC=C2.[Cu+2] InChI=1S/2C9H7NO.Cu/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;/h2*1-6,11H;/q;;+2/p-2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Oxine copper 233-841-9 10380-28-6 copper;quinolin-8-olate Not in list C18H12CuN2O2 C1=CC2=C(C(=C1)[O-])N=CC=C2.C1=CC2=C(C(=C1)[O-])N=CC=C2.[Cu+2] InChI=1S/2C9H7NO.Cu/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;/h2*1-6,11H;/q;;+2/p-2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Oxine copper 233-841-9 10380-28-6 copper;quinolin-8-olate Not in list C18H12CuN2O2 C1=CC2=C(C(=C1)[O-])N=CC=C2.C1=CC2=C(C(=C1)[O-])N=CC=C2.[Cu+2] InChI=1S/2C9H7NO.Cu/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;/h2*1-6,11H;/q;;+2/p-2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Oxine copper 233-841-9 10380-28-6 copper;quinolin-8-olate Not in list C18H12CuN2O2 C1=CC2=C(C(=C1)[O-])N=CC=C2.C1=CC2=C(C(=C1)[O-])N=CC=C2.[Cu+2] InChI=1S/2C9H7NO.Cu/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;/h2*1-6,11H;/q;;+2/p-2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Tribasic copper sulfate 215-582-3 1333-22-8 Tricopper;dihydroxide;disulfate Tribasic copper sulfate Cu3H2O10S2 [OH-].[OH-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Cu+2].[Cu+2].[Cu+2] InChI=1S/3Cu.2H2O4S.2H2O/c;;;2*1-5(2,3)4;;/h;;;2*(H2,1,2,3,4);2*1H2/q3*+2;;;;/p-6 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Oxine copper 233-841-9 10380-28-6 copper;quinolin-8-olate Not in list C18H12CuN2O2 C1=CC2=C(C(=C1)[O-])N=CC=C2.C1=CC2=C(C(=C1)[O-])N=CC=C2.[Cu+2] InChI=1S/2C9H7NO.Cu/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;/h2*1-6,11H;/q;;+2/p-2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Tribasic copper sulfate 215-582-3 1333-22-8 Tricopper;dihydroxide;disulfate Tribasic copper sulfate Cu3H2O10S2 [OH-].[OH-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Cu+2].[Cu+2].[Cu+2] InChI=1S/3Cu.2H2O4S.2H2O/c;;;2*1-5(2,3)4;;/h;;;2*(H2,1,2,3,4);2*1H2/q3*+2;;;;/p-6 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Oxine copper 233-841-9 10380-28-6 copper;quinolin-8-olate Not in list C18H12CuN2O2 C1=CC2=C(C(=C1)[O-])N=CC=C2.C1=CC2=C(C(=C1)[O-])N=CC=C2.[Cu+2] InChI=1S/2C9H7NO.Cu/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;/h2*1-6,11H;/q;;+2/p-2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Tribasic copper sulfate 215-582-3 1333-22-8 Tricopper;dihydroxide;disulfate Tribasic copper sulfate Cu3H2O10S2 [OH-].[OH-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Cu+2].[Cu+2].[Cu+2] InChI=1S/3Cu.2H2O4S.2H2O/c;;;2*1-5(2,3)4;;/h;;;2*(H2,1,2,3,4);2*1H2/q3*+2;;;;/p-6 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Oxine copper 233-841-9 10380-28-6 copper;quinolin-8-olate Not in list C18H12CuN2O2 C1=CC2=C(C(=C1)[O-])N=CC=C2.C1=CC2=C(C(=C1)[O-])N=CC=C2.[Cu+2] InChI=1S/2C9H7NO.Cu/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;/h2*1-6,11H;/q;;+2/p-2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Oxine copper 233-841-9 10380-28-6 copper;quinolin-8-olate Not in list C18H12CuN2O2 C1=CC2=C(C(=C1)[O-])N=CC=C2.C1=CC2=C(C(=C1)[O-])N=CC=C2.[Cu+2] InChI=1S/2C9H7NO.Cu/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;/h2*1-6,11H;/q;;+2/p-2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Oxine copper 233-841-9 10380-28-6 copper;quinolin-8-olate Not in list C18H12CuN2O2 C1=CC2=C(C(=C1)[O-])N=CC=C2.C1=CC2=C(C(=C1)[O-])N=CC=C2.[Cu+2] InChI=1S/2C9H7NO.Cu/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;/h2*1-6,11H;/q;;+2/p-2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Tribasic copper sulfate 215-582-3 1333-22-8 Tricopper;dihydroxide;disulfate Tribasic copper sulfate Cu3H2O10S2 [OH-].[OH-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Cu+2].[Cu+2].[Cu+2] InChI=1S/3Cu.2H2O4S.2H2O/c;;;2*1-5(2,3)4;;/h;;;2*(H2,1,2,3,4);2*1H2/q3*+2;;;;/p-6 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Oxine copper 233-841-9 10380-28-6 copper;quinolin-8-olate Not in list C18H12CuN2O2 C1=CC2=C(C(=C1)[O-])N=CC=C2.C1=CC2=C(C(=C1)[O-])N=CC=C2.[Cu+2] InChI=1S/2C9H7NO.Cu/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;/h2*1-6,11H;/q;;+2/p-2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Positive RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Oxine copper 233-841-9 10380-28-6 copper;quinolin-8-olate Not in list C18H12CuN2O2 C1=CC2=C(C(=C1)[O-])N=CC=C2.C1=CC2=C(C(=C1)[O-])N=CC=C2.[Cu+2] InChI=1S/2C9H7NO.Cu/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;/h2*1-6,11H;/q;;+2/p-2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Oxine copper 233-841-9 10380-28-6 copper;quinolin-8-olate Not in list C18H12CuN2O2 C1=CC2=C(C(=C1)[O-])N=CC=C2.C1=CC2=C(C(=C1)[O-])N=CC=C2.[Cu+2] InChI=1S/2C9H7NO.Cu/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;/h2*1-6,11H;/q;;+2/p-2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Tribasic copper sulfate 215-582-3 1333-22-8 Tricopper;dihydroxide;disulfate Tribasic copper sulfate Cu3H2O10S2 [OH-].[OH-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Cu+2].[Cu+2].[Cu+2] InChI=1S/3Cu.2H2O4S.2H2O/c;;;2*1-5(2,3)4;;/h;;;2*(H2,1,2,3,4);2*1H2/q3*+2;;;;/p-6 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Rat (as animal) hepatocytes Not reported yes without Positive RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Copper chloride 231-210-2 7447-39-4 dichlorocopper Not in list Cl2Cu Cl[Cu]Cl InChI=1S/2ClH.Cu/h2*1H;/q;;+2/p-2 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes with Negative RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Copper chloride 231-210-2 7447-39-4 dichlorocopper Not in list Cl2Cu Cl[Cu]Cl InChI=1S/2ClH.Cu/h2*1H;/q;;+2/p-2 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Copper chloride 231-210-2 7447-39-4 dichlorocopper Not in list Cl2Cu Cl[Cu]Cl InChI=1S/2ClH.Cu/h2*1H;/q;;+2/p-2 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Copper chloride 231-210-2 7447-39-4 dichlorocopper Not in list Cl2Cu Cl[Cu]Cl InChI=1S/2ClH.Cu/h2*1H;/q;;+2/p-2 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Copper chloride 231-210-2 7447-39-4 dichlorocopper Not in list Cl2Cu Cl[Cu]Cl InChI=1S/2ClH.Cu/h2*1H;/q;;+2/p-2 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Copper chloride 231-210-2 7447-39-4 dichlorocopper Not in list Cl2Cu Cl[Cu]Cl InChI=1S/2ClH.Cu/h2*1H;/q;;+2/p-2 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Copper chloride 231-210-2 7447-39-4 dichlorocopper Not in list Cl2Cu Cl[Cu]Cl InChI=1S/2ClH.Cu/h2*1H;/q;;+2/p-2 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Copper chloride 231-210-2 7447-39-4 dichlorocopper Not in list Cl2Cu Cl[Cu]Cl InChI=1S/2ClH.Cu/h2*1H;/q;;+2/p-2 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes without Negative RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Copper chloride 231-210-2 7447-39-4 dichlorocopper Not in list Cl2Cu Cl[Cu]Cl InChI=1S/2ClH.Cu/h2*1H;/q;;+2/p-2 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported no data no data Negative RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Copper chloride 231-210-2 7447-39-4 dichlorocopper Not in list Cl2Cu Cl[Cu]Cl InChI=1S/2ClH.Cu/h2*1H;/q;;+2/p-2 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported no data no data Negative RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Copper nitrate 221-838-5 3251-23-8 copper;dinitrate Not in list CuN2O6 [N+](=O)([O-])[O-].[N+](=O)([O-])[O-].[Cu+2] InChI=1S/Cu.2NO3/c;2*2-1(3)4/q+2;2*-1 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data no data Positive RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Copper nitrate 221-838-5 3251-23-8 copper;dinitrate Not in list CuN2O6 [N+](=O)([O-])[O-].[N+](=O)([O-])[O-].[Cu+2] InChI=1S/Cu.2NO3/c;2*2-1(3)4/q+2;2*-1 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data no data Positive RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Copper II sulphate pentahydrate 616-477-9 7758-99-8 copper;sulfate;pentahydrate Not in list CuSO4.5H2O O.O.O.O.O.[O-]S(=O)(=O)[O-].[Cu+2] InChI=1S/Cu.H2O4S.5H2O/c;1-5(2,3)4;;;;;/h;(H2,1,2,3,4);5*1H2/q+2;;;;;;/p-2 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Wistar 5 Male oral: gavage 4.0000000000 h yes, concurrent vehicle not applicable Negative RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Copper II sulphate pentahydrate 616-477-9 7758-99-8 copper;sulfate;pentahydrate Not in list CuSO4.5H2O O.O.O.O.O.[O-]S(=O)(=O)[O-].[Cu+2] InChI=1S/Cu.H2O4S.5H2O/c;1-5(2,3)4;;;;;/h;(H2,1,2,3,4);5*1H2/q+2;;;;;;/p-2 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Wistar 5 Male oral: gavage 14.0000000000 h yes, concurrent vehicle not applicable Negative RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Copper II sulphate pentahydrate 616-477-9 7758-99-8 copper;sulfate;pentahydrate Not in list CuSO4.5H2O O.O.O.O.O.[O-]S(=O)(=O)[O-].[Cu+2] InChI=1S/Cu.H2O4S.5H2O/c;1-5(2,3)4;;;;;/h;(H2,1,2,3,4);5*1H2/q+2;;;;;;/p-2 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Copper II sulphate pentahydrate 616-477-9 7758-99-8 copper;sulfate;pentahydrate Not in list CuSO4.5H2O O.O.O.O.O.[O-]S(=O)(=O)[O-].[Cu+2] InChI=1S/Cu.H2O4S.5H2O/c;1-5(2,3)4;;;;;/h;(H2,1,2,3,4);5*1H2/q+2;;;;;;/p-2 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity$indirect evidence-systemic toxicity RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Tribasic copper sulfate 215-582-3 1333-22-8 Tricopper;dihydroxide;disulfate Tribasic copper sulfate Cu3H2O10S2 [OH-].[OH-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Cu+2].[Cu+2].[Cu+2] InChI=1S/3Cu.2H2O4S.2H2O/c;;;2*1-5(2,3)4;;/h;;;2*(H2,1,2,3,4);2*1H2/q3*+2;;;;/p-6 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) Swiss No data intraperitoneal 6.0000000000 h yes, concurrent vehicle not applicable Positive RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Tribasic copper sulfate 215-582-3 1333-22-8 Tricopper;dihydroxide;disulfate Tribasic copper sulfate Cu3H2O10S2 [OH-].[OH-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Cu+2].[Cu+2].[Cu+2] InChI=1S/3Cu.2H2O4S.2H2O/c;;;2*1-5(2,3)4;;/h;;;2*(H2,1,2,3,4);2*1H2/q3*+2;;;;/p-6 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Swiss 3 No data intraperitoneal 6.0000000000 h no data not applicable Positive no evidence RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Tribasic copper sulfate 215-582-3 1333-22-8 Tricopper;dihydroxide;disulfate Tribasic copper sulfate Cu3H2O10S2 [OH-].[OH-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Cu+2].[Cu+2].[Cu+2] InChI=1S/3Cu.2H2O4S.2H2O/c;;;2*1-5(2,3)4;;/h;;;2*(H2,1,2,3,4);2*1H2/q3*+2;;;;/p-6 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) Swiss No data subcutaneous 24.0000000000 h yes, concurrent vehicle not applicable Positive RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Tribasic copper sulfate 215-582-3 1333-22-8 Tricopper;dihydroxide;disulfate Tribasic copper sulfate Cu3H2O10S2 [OH-].[OH-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Cu+2].[Cu+2].[Cu+2] InChI=1S/3Cu.2H2O4S.2H2O/c;;;2*1-5(2,3)4;;/h;;;2*(H2,1,2,3,4);2*1H2/q3*+2;;;;/p-6 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) Swiss No data intraperitoneal 24.0000000000 h yes, concurrent vehicle not applicable Positive RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Tribasic copper sulfate 215-582-3 1333-22-8 Tricopper;dihydroxide;disulfate Tribasic copper sulfate Cu3H2O10S2 [OH-].[OH-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Cu+2].[Cu+2].[Cu+2] InChI=1S/3Cu.2H2O4S.2H2O/c;;;2*1-5(2,3)4;;/h;;;2*(H2,1,2,3,4);2*1H2/q3*+2;;;;/p-6 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) Swiss No data oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Positive RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Tribasic copper sulfate 215-582-3 1333-22-8 Tricopper;dihydroxide;disulfate Tribasic copper sulfate Cu3H2O10S2 [OH-].[OH-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Cu+2].[Cu+2].[Cu+2] InChI=1S/3Cu.2H2O4S.2H2O/c;;;2*1-5(2,3)4;;/h;;;2*(H2,1,2,3,4);2*1H2/q3*+2;;;;/p-6 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) Swiss No data intraperitoneal 48.0000000000 h yes, concurrent vehicle not applicable Positive RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Copper II sulphate pentahydrate 616-477-9 7758-99-8 copper;sulfate;pentahydrate Not in list CuSO4.5H2O O.O.O.O.O.[O-]S(=O)(=O)[O-].[Cu+2] InChI=1S/Cu.H2O4S.5H2O/c;1-5(2,3)4;;;;;/h;(H2,1,2,3,4);5*1H2/q+2;;;;;;/p-2 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable House mouse (as animal) Swiss 6 Male intraperitoneal 6.0000000000 h yes not applicable Positive RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Copper II sulphate pentahydrate 616-477-9 7758-99-8 copper;sulfate;pentahydrate Not in list CuSO4.5H2O O.O.O.O.O.[O-]S(=O)(=O)[O-].[Cu+2] InChI=1S/Cu.H2O4S.5H2O/c;1-5(2,3)4;;;;;/h;(H2,1,2,3,4);5*1H2/q+2;;;;;;/p-2 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable House mouse (as animal) Swiss 6 Male intraperitoneal 12.0000000000 h yes not applicable Positive RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Copper II sulphate pentahydrate 616-477-9 7758-99-8 copper;sulfate;pentahydrate Not in list CuSO4.5H2O O.O.O.O.O.[O-]S(=O)(=O)[O-].[Cu+2] InChI=1S/Cu.H2O4S.5H2O/c;1-5(2,3)4;;;;;/h;(H2,1,2,3,4);5*1H2/q+2;;;;;;/p-2 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable House mouse (as animal) Swiss 6 Male intraperitoneal 24.0000000000 h yes not applicable Positive RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Tribasic copper sulfate 215-582-3 1333-22-8 Tricopper;dihydroxide;disulfate Tribasic copper sulfate Cu3H2O10S2 [OH-].[OH-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Cu+2].[Cu+2].[Cu+2] InChI=1S/3Cu.2H2O4S.2H2O/c;;;2*1-5(2,3)4;;/h;;;2*(H2,1,2,3,4);2*1H2/q3*+2;;;;/p-6 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CBA 6 Male intraperitoneal 48.0000000000 h yes not applicable Negative direct evidence-cytotoxicity RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Copper 231-159-6 7440-50-8 single chemical entity Component is part of a group assessment Tribasic copper sulfate 215-582-3 1333-22-8 Tricopper;dihydroxide;disulfate Tribasic copper sulfate Cu3H2O10S2 [OH-].[OH-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Cu+2].[Cu+2].[Cu+2] InChI=1S/3Cu.2H2O4S.2H2O/c;;;2*1-5(2,3)4;;/h;;;2*(H2,1,2,3,4);2*1H2/q3*+2;;;;/p-6 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CBA 6 Male intraperitoneal 24.0000000000 h yes not applicable Negative direct evidence-cytotoxicity RMS: France Copper 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture. 22Oct2008 2008 doi:10.2903/j.efsa.2008.187r
+Flufenoxuron 417-680-3 101463-69-8 single chemical entity Component is identical to the substance Flufenoxuron 417-680-3 101463-69-8 N-({4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}carbamoyl)-2,6-difluorobenzamide Flufenoxuron C21H11ClF6N2O3 O=C(NC(NC2=C(F)C=C(OC3=C(Cl)C=C(C(F)(F)F)C=C3)C=C2)=O)C1=C(F)C=CC=C1F InChI=1S/C21H11ClF6N2O3/c22-12-8-10(21(26,27)28)4-7-17(12)33-11-5-6-16(15(25)9-11)29-20(32)30-19(31)18-13(23)2-1-3-14(18)24/h1-9H,(H2,29,30,31,32) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: France Flufenoxuron 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron 14Mar2011 2011 doi:10.2903/j.efsa.2011.2088
+Flufenoxuron 417-680-3 101463-69-8 single chemical entity Component is identical to the substance Flufenoxuron 417-680-3 101463-69-8 N-({4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}carbamoyl)-2,6-difluorobenzamide Flufenoxuron C21H11ClF6N2O3 O=C(NC(NC2=C(F)C=C(OC3=C(Cl)C=C(C(F)(F)F)C=C3)C=C2)=O)C1=C(F)C=CC=C1F InChI=1S/C21H11ClF6N2O3/c22-12-8-10(21(26,27)28)4-7-17(12)33-11-5-6-16(15(25)9-11)29-20(32)30-19(31)18-13(23)2-1-3-14(18)24/h1-9H,(H2,29,30,31,32) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: France Flufenoxuron 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron 14Mar2011 2011 doi:10.2903/j.efsa.2011.2088
+Flufenoxuron 417-680-3 101463-69-8 single chemical entity Component is identical to the substance Flufenoxuron 417-680-3 101463-69-8 N-({4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}carbamoyl)-2,6-difluorobenzamide Flufenoxuron C21H11ClF6N2O3 O=C(NC(NC2=C(F)C=C(OC3=C(Cl)C=C(C(F)(F)F)C=C3)C=C2)=O)C1=C(F)C=CC=C1F InChI=1S/C21H11ClF6N2O3/c22-12-8-10(21(26,27)28)4-7-17(12)33-11-5-6-16(15(25)9-11)29-20(32)30-19(31)18-13(23)2-1-3-14(18)24/h1-9H,(H2,29,30,31,32) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: France Flufenoxuron 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron 14Mar2011 2011 doi:10.2903/j.efsa.2011.2088
+Flufenoxuron 417-680-3 101463-69-8 single chemical entity Component is identical to the substance Flufenoxuron 417-680-3 101463-69-8 N-({4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}carbamoyl)-2,6-difluorobenzamide Flufenoxuron C21H11ClF6N2O3 O=C(NC(NC2=C(F)C=C(OC3=C(Cl)C=C(C(F)(F)F)C=C3)C=C2)=O)C1=C(F)C=CC=C1F InChI=1S/C21H11ClF6N2O3/c22-12-8-10(21(26,27)28)4-7-17(12)33-11-5-6-16(15(25)9-11)29-20(32)30-19(31)18-13(23)2-1-3-14(18)24/h1-9H,(H2,29,30,31,32) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: France Flufenoxuron 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron 14Mar2011 2011 doi:10.2903/j.efsa.2011.2088
+Flufenoxuron 417-680-3 101463-69-8 single chemical entity Component is identical to the substance Flufenoxuron 417-680-3 101463-69-8 N-({4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}carbamoyl)-2,6-difluorobenzamide Flufenoxuron C21H11ClF6N2O3 O=C(NC(NC2=C(F)C=C(OC3=C(Cl)C=C(C(F)(F)F)C=C3)C=C2)=O)C1=C(F)C=CC=C1F InChI=1S/C21H11ClF6N2O3/c22-12-8-10(21(26,27)28)4-7-17(12)33-11-5-6-16(15(25)9-11)29-20(32)30-19(31)18-13(23)2-1-3-14(18)24/h1-9H,(H2,29,30,31,32) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: France Flufenoxuron 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron 14Mar2011 2011 doi:10.2903/j.efsa.2011.2088
+Flufenoxuron 417-680-3 101463-69-8 single chemical entity Component is identical to the substance Flufenoxuron 417-680-3 101463-69-8 N-({4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}carbamoyl)-2,6-difluorobenzamide Flufenoxuron C21H11ClF6N2O3 O=C(NC(NC2=C(F)C=C(OC3=C(Cl)C=C(C(F)(F)F)C=C3)C=C2)=O)C1=C(F)C=CC=C1F InChI=1S/C21H11ClF6N2O3/c22-12-8-10(21(26,27)28)4-7-17(12)33-11-5-6-16(15(25)9-11)29-20(32)30-19(31)18-13(23)2-1-3-14(18)24/h1-9H,(H2,29,30,31,32) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: France Flufenoxuron 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron 14Mar2011 2011 doi:10.2903/j.efsa.2011.2088
+Flufenoxuron 417-680-3 101463-69-8 single chemical entity Component is identical to the substance Flufenoxuron 417-680-3 101463-69-8 N-({4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}carbamoyl)-2,6-difluorobenzamide Flufenoxuron C21H11ClF6N2O3 O=C(NC(NC2=C(F)C=C(OC3=C(Cl)C=C(C(F)(F)F)C=C3)C=C2)=O)C1=C(F)C=CC=C1F InChI=1S/C21H11ClF6N2O3/c22-12-8-10(21(26,27)28)4-7-17(12)33-11-5-6-16(15(25)9-11)29-20(32)30-19(31)18-13(23)2-1-3-14(18)24/h1-9H,(H2,29,30,31,32) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: France Flufenoxuron 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron 14Mar2011 2011 doi:10.2903/j.efsa.2011.2088
+Flufenoxuron 417-680-3 101463-69-8 single chemical entity Component is identical to the substance Flufenoxuron 417-680-3 101463-69-8 N-({4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}carbamoyl)-2,6-difluorobenzamide Flufenoxuron C21H11ClF6N2O3 O=C(NC(NC2=C(F)C=C(OC3=C(Cl)C=C(C(F)(F)F)C=C3)C=C2)=O)C1=C(F)C=CC=C1F InChI=1S/C21H11ClF6N2O3/c22-12-8-10(21(26,27)28)4-7-17(12)33-11-5-6-16(15(25)9-11)29-20(32)30-19(31)18-13(23)2-1-3-14(18)24/h1-9H,(H2,29,30,31,32) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: France Flufenoxuron 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron 14Mar2011 2011 doi:10.2903/j.efsa.2011.2088
+Flufenoxuron 417-680-3 101463-69-8 single chemical entity Component is identical to the substance Flufenoxuron 417-680-3 101463-69-8 N-({4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}carbamoyl)-2,6-difluorobenzamide Flufenoxuron C21H11ClF6N2O3 O=C(NC(NC2=C(F)C=C(OC3=C(Cl)C=C(C(F)(F)F)C=C3)C=C2)=O)C1=C(F)C=CC=C1F InChI=1S/C21H11ClF6N2O3/c22-12-8-10(21(26,27)28)4-7-17(12)33-11-5-6-16(15(25)9-11)29-20(32)30-19(31)18-13(23)2-1-3-14(18)24/h1-9H,(H2,29,30,31,32) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: France Flufenoxuron 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron 14Mar2011 2011 doi:10.2903/j.efsa.2011.2088
+Flufenoxuron 417-680-3 101463-69-8 single chemical entity Component is identical to the substance Flufenoxuron 417-680-3 101463-69-8 N-({4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}carbamoyl)-2,6-difluorobenzamide Flufenoxuron C21H11ClF6N2O3 O=C(NC(NC2=C(F)C=C(OC3=C(Cl)C=C(C(F)(F)F)C=C3)C=C2)=O)C1=C(F)C=CC=C1F InChI=1S/C21H11ClF6N2O3/c22-12-8-10(21(26,27)28)4-7-17(12)33-11-5-6-16(15(25)9-11)29-20(32)30-19(31)18-13(23)2-1-3-14(18)24/h1-9H,(H2,29,30,31,32) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: France Flufenoxuron 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron 14Mar2011 2011 doi:10.2903/j.efsa.2011.2088
+Flufenoxuron 417-680-3 101463-69-8 single chemical entity Component is identical to the substance Flufenoxuron 417-680-3 101463-69-8 N-({4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}carbamoyl)-2,6-difluorobenzamide Flufenoxuron C21H11ClF6N2O3 O=C(NC(NC2=C(F)C=C(OC3=C(Cl)C=C(C(F)(F)F)C=C3)C=C2)=O)C1=C(F)C=CC=C1F InChI=1S/C21H11ClF6N2O3/c22-12-8-10(21(26,27)28)4-7-17(12)33-11-5-6-16(15(25)9-11)29-20(32)30-19(31)18-13(23)2-1-3-14(18)24/h1-9H,(H2,29,30,31,32) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: France Flufenoxuron 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron 14Mar2011 2011 doi:10.2903/j.efsa.2011.2088
+Flufenoxuron 417-680-3 101463-69-8 single chemical entity Component is identical to the substance Flufenoxuron 417-680-3 101463-69-8 N-({4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}carbamoyl)-2,6-difluorobenzamide Flufenoxuron C21H11ClF6N2O3 O=C(NC(NC2=C(F)C=C(OC3=C(Cl)C=C(C(F)(F)F)C=C3)C=C2)=O)C1=C(F)C=CC=C1F InChI=1S/C21H11ClF6N2O3/c22-12-8-10(21(26,27)28)4-7-17(12)33-11-5-6-16(15(25)9-11)29-20(32)30-19(31)18-13(23)2-1-3-14(18)24/h1-9H,(H2,29,30,31,32) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Negative RMS: France Flufenoxuron 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron 14Mar2011 2011 doi:10.2903/j.efsa.2011.2088
+Flufenoxuron 417-680-3 101463-69-8 single chemical entity Component is identical to the substance Flufenoxuron 417-680-3 101463-69-8 N-({4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}carbamoyl)-2,6-difluorobenzamide Flufenoxuron C21H11ClF6N2O3 O=C(NC(NC2=C(F)C=C(OC3=C(Cl)C=C(C(F)(F)F)C=C3)C=C2)=O)C1=C(F)C=CC=C1F InChI=1S/C21H11ClF6N2O3/c22-12-8-10(21(26,27)28)4-7-17(12)33-11-5-6-16(15(25)9-11)29-20(32)30-19(31)18-13(23)2-1-3-14(18)24/h1-9H,(H2,29,30,31,32) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Positive RMS: France Flufenoxuron 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron 14Mar2011 2011 doi:10.2903/j.efsa.2011.2088
+Flufenoxuron 417-680-3 101463-69-8 single chemical entity Component is identical to the substance Flufenoxuron 417-680-3 101463-69-8 N-({4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}carbamoyl)-2,6-difluorobenzamide Flufenoxuron C21H11ClF6N2O3 O=C(NC(NC2=C(F)C=C(OC3=C(Cl)C=C(C(F)(F)F)C=C3)C=C2)=O)C1=C(F)C=CC=C1F InChI=1S/C21H11ClF6N2O3/c22-12-8-10(21(26,27)28)4-7-17(12)33-11-5-6-16(15(25)9-11)29-20(32)30-19(31)18-13(23)2-1-3-14(18)24/h1-9H,(H2,29,30,31,32) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) ICR 6 Male intraperitoneal 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: France Flufenoxuron 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron 14Mar2011 2011 doi:10.2903/j.efsa.2011.2088
+Flufenoxuron 417-680-3 101463-69-8 single chemical entity Component is identical to the substance Flufenoxuron 417-680-3 101463-69-8 N-({4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}carbamoyl)-2,6-difluorobenzamide Flufenoxuron C21H11ClF6N2O3 O=C(NC(NC2=C(F)C=C(OC3=C(Cl)C=C(C(F)(F)F)C=C3)C=C2)=O)C1=C(F)C=CC=C1F InChI=1S/C21H11ClF6N2O3/c22-12-8-10(21(26,27)28)4-7-17(12)33-11-5-6-16(15(25)9-11)29-20(32)30-19(31)18-13(23)2-1-3-14(18)24/h1-9H,(H2,29,30,31,32) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) ICR 6 Male intraperitoneal 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: France Flufenoxuron 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron 14Mar2011 2011 doi:10.2903/j.efsa.2011.2088
+Flufenoxuron 417-680-3 101463-69-8 single chemical entity Component is identical to the substance Flufenoxuron 417-680-3 101463-69-8 N-({4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}carbamoyl)-2,6-difluorobenzamide Flufenoxuron C21H11ClF6N2O3 O=C(NC(NC2=C(F)C=C(OC3=C(Cl)C=C(C(F)(F)F)C=C3)C=C2)=O)C1=C(F)C=CC=C1F InChI=1S/C21H11ClF6N2O3/c22-12-8-10(21(26,27)28)4-7-17(12)33-11-5-6-16(15(25)9-11)29-20(32)30-19(31)18-13(23)2-1-3-14(18)24/h1-9H,(H2,29,30,31,32) organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Rat (as animal) Wistar 24 Male/Female oral: unspecified 48.0000000000 h yes, concurrent vehicle not applicable Negative RMS: France Flufenoxuron 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron 14Mar2011 2011 doi:10.2903/j.efsa.2011.2088
+Flufenoxuron 417-680-3 101463-69-8 single chemical entity Component is identical to the substance Flufenoxuron 417-680-3 101463-69-8 N-({4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}carbamoyl)-2,6-difluorobenzamide Flufenoxuron C21H11ClF6N2O3 O=C(NC(NC2=C(F)C=C(OC3=C(Cl)C=C(C(F)(F)F)C=C3)C=C2)=O)C1=C(F)C=CC=C1F InChI=1S/C21H11ClF6N2O3/c22-12-8-10(21(26,27)28)4-7-17(12)33-11-5-6-16(15(25)9-11)29-20(32)30-19(31)18-13(23)2-1-3-14(18)24/h1-9H,(H2,29,30,31,32) organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Rat (as animal) Wistar 24 Male/Female oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: France Flufenoxuron 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron 14Mar2011 2011 doi:10.2903/j.efsa.2011.2088
+Flufenoxuron 417-680-3 101463-69-8 single chemical entity Component is identical to the substance Flufenoxuron 417-680-3 101463-69-8 N-({4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}carbamoyl)-2,6-difluorobenzamide Flufenoxuron C21H11ClF6N2O3 O=C(NC(NC2=C(F)C=C(OC3=C(Cl)C=C(C(F)(F)F)C=C3)C=C2)=O)C1=C(F)C=CC=C1F InChI=1S/C21H11ClF6N2O3/c22-12-8-10(21(26,27)28)4-7-17(12)33-11-5-6-16(15(25)9-11)29-20(32)30-19(31)18-13(23)2-1-3-14(18)24/h1-9H,(H2,29,30,31,32) organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Fischer344 Male oral: gavage 4.0000000000 h yes, concurrent vehicle not applicable Negative RMS: France Flufenoxuron 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron 14Mar2011 2011 doi:10.2903/j.efsa.2011.2088
+Flufenoxuron 417-680-3 101463-69-8 single chemical entity Component is a metabolite of the substance N-[4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl urea 1-{4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}urea Not in list C14H9ClF4N2O2 Clc2cc(ccc2Oc1ccc(NC(N)=O)c(F)c1)C(F)(F)F InChI=1/C14H9ClF4N2O2/c15-9-5-7(14(17,18)19)1-4-12(9)23-8-2-3-11(10(16)6-8)21-13(20)22/h1-6H,(H3,20,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Flufenoxuron 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron 14Mar2011 2011 doi:10.2903/j.efsa.2011.2088
+Flufenoxuron 417-680-3 101463-69-8 single chemical entity Component is a metabolite of the substance N-[4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl urea 1-{4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}urea Not in list C14H9ClF4N2O2 Clc2cc(ccc2Oc1ccc(NC(N)=O)c(F)c1)C(F)(F)F InChI=1/C14H9ClF4N2O2/c15-9-5-7(14(17,18)19)1-4-12(9)23-8-2-3-11(10(16)6-8)21-13(20)22/h1-6H,(H3,20,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: France Flufenoxuron 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron 14Mar2011 2011 doi:10.2903/j.efsa.2011.2088
+Flufenoxuron 417-680-3 101463-69-8 single chemical entity Component is a metabolite of the substance N-[4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl urea 1-{4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}urea Not in list C14H9ClF4N2O2 Clc2cc(ccc2Oc1ccc(NC(N)=O)c(F)c1)C(F)(F)F InChI=1/C14H9ClF4N2O2/c15-9-5-7(14(17,18)19)1-4-12(9)23-8-2-3-11(10(16)6-8)21-13(20)22/h1-6H,(H3,20,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle without Negative RMS: France Flufenoxuron 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron 14Mar2011 2011 doi:10.2903/j.efsa.2011.2088
+Flufenoxuron 417-680-3 101463-69-8 single chemical entity Component is a metabolite of the substance N-[4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl urea 1-{4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}urea Not in list C14H9ClF4N2O2 Clc2cc(ccc2Oc1ccc(NC(N)=O)c(F)c1)C(F)(F)F InChI=1/C14H9ClF4N2O2/c15-9-5-7(14(17,18)19)1-4-12(9)23-8-2-3-11(10(16)6-8)21-13(20)22/h1-6H,(H3,20,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: France Flufenoxuron 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron 14Mar2011 2011 doi:10.2903/j.efsa.2011.2088
+Flufenoxuron 417-680-3 101463-69-8 single chemical entity Component is a metabolite of the substance N-[4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl urea 1-{4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}urea Not in list C14H9ClF4N2O2 Clc2cc(ccc2Oc1ccc(NC(N)=O)c(F)c1)C(F)(F)F InChI=1/C14H9ClF4N2O2/c15-9-5-7(14(17,18)19)1-4-12(9)23-8-2-3-11(10(16)6-8)21-13(20)22/h1-6H,(H3,20,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Flufenoxuron 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron 14Mar2011 2011 doi:10.2903/j.efsa.2011.2088
+Flufenoxuron 417-680-3 101463-69-8 single chemical entity Component is a metabolite of the substance N-[4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl urea 1-{4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}urea Not in list C14H9ClF4N2O2 Clc2cc(ccc2Oc1ccc(NC(N)=O)c(F)c1)C(F)(F)F InChI=1/C14H9ClF4N2O2/c15-9-5-7(14(17,18)19)1-4-12(9)23-8-2-3-11(10(16)6-8)21-13(20)22/h1-6H,(H3,20,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Flufenoxuron 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron 14Mar2011 2011 doi:10.2903/j.efsa.2011.2088
+Flufenoxuron 417-680-3 101463-69-8 single chemical entity Component is a metabolite of the substance N-[4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl urea 1-{4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}urea Not in list C14H9ClF4N2O2 Clc2cc(ccc2Oc1ccc(NC(N)=O)c(F)c1)C(F)(F)F InChI=1/C14H9ClF4N2O2/c15-9-5-7(14(17,18)19)1-4-12(9)23-8-2-3-11(10(16)6-8)21-13(20)22/h1-6H,(H3,20,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Flufenoxuron 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron 14Mar2011 2011 doi:10.2903/j.efsa.2011.2088
+Flufenoxuron 417-680-3 101463-69-8 single chemical entity Component is a metabolite of the substance N-[4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl urea 1-{4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}urea Not in list C14H9ClF4N2O2 Clc2cc(ccc2Oc1ccc(NC(N)=O)c(F)c1)C(F)(F)F InChI=1/C14H9ClF4N2O2/c15-9-5-7(14(17,18)19)1-4-12(9)23-8-2-3-11(10(16)6-8)21-13(20)22/h1-6H,(H3,20,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Flufenoxuron 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron 14Mar2011 2011 doi:10.2903/j.efsa.2011.2088
+Flufenoxuron 417-680-3 101463-69-8 single chemical entity Component is a metabolite of the substance N-[4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl urea 1-{4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}urea Not in list C14H9ClF4N2O2 Clc2cc(ccc2Oc1ccc(NC(N)=O)c(F)c1)C(F)(F)F InChI=1/C14H9ClF4N2O2/c15-9-5-7(14(17,18)19)1-4-12(9)23-8-2-3-11(10(16)6-8)21-13(20)22/h1-6H,(H3,20,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Flufenoxuron 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron 14Mar2011 2011 doi:10.2903/j.efsa.2011.2088
+Flufenoxuron 417-680-3 101463-69-8 single chemical entity Component is a metabolite of the substance N-[4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl urea 1-{4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}urea Not in list C14H9ClF4N2O2 Clc2cc(ccc2Oc1ccc(NC(N)=O)c(F)c1)C(F)(F)F InChI=1/C14H9ClF4N2O2/c15-9-5-7(14(17,18)19)1-4-12(9)23-8-2-3-11(10(16)6-8)21-13(20)22/h1-6H,(H3,20,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Flufenoxuron 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron 14Mar2011 2011 doi:10.2903/j.efsa.2011.2088
+Flufenoxuron 417-680-3 101463-69-8 single chemical entity Component is a metabolite of the substance N-[4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl urea 1-{4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}urea Not in list C14H9ClF4N2O2 Clc2cc(ccc2Oc1ccc(NC(N)=O)c(F)c1)C(F)(F)F InChI=1/C14H9ClF4N2O2/c15-9-5-7(14(17,18)19)1-4-12(9)23-8-2-3-11(10(16)6-8)21-13(20)22/h1-6H,(H3,20,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Flufenoxuron 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron 14Mar2011 2011 doi:10.2903/j.efsa.2011.2088
+Flufenoxuron 417-680-3 101463-69-8 single chemical entity Component is a metabolite of the substance N-[4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl urea 1-{4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}urea Not in list C14H9ClF4N2O2 Clc2cc(ccc2Oc1ccc(NC(N)=O)c(F)c1)C(F)(F)F InChI=1/C14H9ClF4N2O2/c15-9-5-7(14(17,18)19)1-4-12(9)23-8-2-3-11(10(16)6-8)21-13(20)22/h1-6H,(H3,20,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle with Negative RMS: France Flufenoxuron 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron 14Mar2011 2011 doi:10.2903/j.efsa.2011.2088
+Flufenoxuron 417-680-3 101463-69-8 single chemical entity Component is a metabolite of the substance 4-[2-Chloro-4-(trifluoromethyl)phenoxy-2-fluorobenzenamine 4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluoroaniline Not in list C13H8ClF4NO Clc2cc(ccc2Oc1ccc(N)c(F)c1)C(F)(F)F InChI=1/C13H8ClF4NO/c14-9-5-7(13(16,17)18)1-4-12(9)20-8-2-3-11(19)10(15)6-8/h1-6H,19H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Flufenoxuron 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron 14Mar2011 2011 doi:10.2903/j.efsa.2011.2088
+Flufenoxuron 417-680-3 101463-69-8 single chemical entity Component is a metabolite of the substance 4-[2-Chloro-4-(trifluoromethyl)phenoxy-2-fluorobenzenamine 4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluoroaniline Not in list C13H8ClF4NO Clc2cc(ccc2Oc1ccc(N)c(F)c1)C(F)(F)F InChI=1/C13H8ClF4NO/c14-9-5-7(13(16,17)18)1-4-12(9)20-8-2-3-11(19)10(15)6-8/h1-6H,19H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: France Flufenoxuron 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron 14Mar2011 2011 doi:10.2903/j.efsa.2011.2088
+Flufenoxuron 417-680-3 101463-69-8 single chemical entity Component is a metabolite of the substance 4-[2-Chloro-4-(trifluoromethyl)phenoxy-2-fluorobenzenamine 4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluoroaniline Not in list C13H8ClF4NO Clc2cc(ccc2Oc1ccc(N)c(F)c1)C(F)(F)F InChI=1/C13H8ClF4NO/c14-9-5-7(13(16,17)18)1-4-12(9)20-8-2-3-11(19)10(15)6-8/h1-6H,19H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle without Negative RMS: France Flufenoxuron 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron 14Mar2011 2011 doi:10.2903/j.efsa.2011.2088
+Flufenoxuron 417-680-3 101463-69-8 single chemical entity Component is a metabolite of the substance 4-[2-Chloro-4-(trifluoromethyl)phenoxy-2-fluorobenzenamine 4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluoroaniline Not in list C13H8ClF4NO Clc2cc(ccc2Oc1ccc(N)c(F)c1)C(F)(F)F InChI=1/C13H8ClF4NO/c14-9-5-7(13(16,17)18)1-4-12(9)20-8-2-3-11(19)10(15)6-8/h1-6H,19H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle with Negative RMS: France Flufenoxuron 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron 14Mar2011 2011 doi:10.2903/j.efsa.2011.2088
+Flufenoxuron 417-680-3 101463-69-8 single chemical entity Component is a metabolite of the substance 4-[2-Chloro-4-(trifluoromethyl)phenoxy-2-fluorobenzenamine 4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluoroaniline Not in list C13H8ClF4NO Clc2cc(ccc2Oc1ccc(N)c(F)c1)C(F)(F)F InChI=1/C13H8ClF4NO/c14-9-5-7(13(16,17)18)1-4-12(9)20-8-2-3-11(19)10(15)6-8/h1-6H,19H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Flufenoxuron 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron 14Mar2011 2011 doi:10.2903/j.efsa.2011.2088
+Flufenoxuron 417-680-3 101463-69-8 single chemical entity Component is a metabolite of the substance 4-[2-Chloro-4-(trifluoromethyl)phenoxy-2-fluorobenzenamine 4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluoroaniline Not in list C13H8ClF4NO Clc2cc(ccc2Oc1ccc(N)c(F)c1)C(F)(F)F InChI=1/C13H8ClF4NO/c14-9-5-7(13(16,17)18)1-4-12(9)20-8-2-3-11(19)10(15)6-8/h1-6H,19H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: France Flufenoxuron 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron 14Mar2011 2011 doi:10.2903/j.efsa.2011.2088
+Flufenoxuron 417-680-3 101463-69-8 single chemical entity Component is a metabolite of the substance 4-[2-Chloro-4-(trifluoromethyl)phenoxy-2-fluorobenzenamine 4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluoroaniline Not in list C13H8ClF4NO Clc2cc(ccc2Oc1ccc(N)c(F)c1)C(F)(F)F InChI=1/C13H8ClF4NO/c14-9-5-7(13(16,17)18)1-4-12(9)20-8-2-3-11(19)10(15)6-8/h1-6H,19H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Flufenoxuron 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron 14Mar2011 2011 doi:10.2903/j.efsa.2011.2088
+Flufenoxuron 417-680-3 101463-69-8 single chemical entity Component is a metabolite of the substance 4-[2-Chloro-4-(trifluoromethyl)phenoxy-2-fluorobenzenamine 4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluoroaniline Not in list C13H8ClF4NO Clc2cc(ccc2Oc1ccc(N)c(F)c1)C(F)(F)F InChI=1/C13H8ClF4NO/c14-9-5-7(13(16,17)18)1-4-12(9)20-8-2-3-11(19)10(15)6-8/h1-6H,19H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Flufenoxuron 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron 14Mar2011 2011 doi:10.2903/j.efsa.2011.2088
+Flufenoxuron 417-680-3 101463-69-8 single chemical entity Component is a metabolite of the substance 4-[2-Chloro-4-(trifluoromethyl)phenoxy-2-fluorobenzenamine 4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluoroaniline Not in list C13H8ClF4NO Clc2cc(ccc2Oc1ccc(N)c(F)c1)C(F)(F)F InChI=1/C13H8ClF4NO/c14-9-5-7(13(16,17)18)1-4-12(9)20-8-2-3-11(19)10(15)6-8/h1-6H,19H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Flufenoxuron 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron 14Mar2011 2011 doi:10.2903/j.efsa.2011.2088
+Flufenoxuron 417-680-3 101463-69-8 single chemical entity Component is a metabolite of the substance 4-[2-Chloro-4-(trifluoromethyl)phenoxy-2-fluorobenzenamine 4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluoroaniline Not in list C13H8ClF4NO Clc2cc(ccc2Oc1ccc(N)c(F)c1)C(F)(F)F InChI=1/C13H8ClF4NO/c14-9-5-7(13(16,17)18)1-4-12(9)20-8-2-3-11(19)10(15)6-8/h1-6H,19H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Positive RMS: France Flufenoxuron 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron 14Mar2011 2011 doi:10.2903/j.efsa.2011.2088
+Flufenoxuron 417-680-3 101463-69-8 single chemical entity Component is a metabolite of the substance 4-[2-Chloro-4-(trifluoromethyl)phenoxy-2-fluorobenzenamine 4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluoroaniline Not in list C13H8ClF4NO Clc2cc(ccc2Oc1ccc(N)c(F)c1)C(F)(F)F InChI=1/C13H8ClF4NO/c14-9-5-7(13(16,17)18)1-4-12(9)20-8-2-3-11(19)10(15)6-8/h1-6H,19H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Flufenoxuron 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron 14Mar2011 2011 doi:10.2903/j.efsa.2011.2088
+Flufenoxuron 417-680-3 101463-69-8 single chemical entity Component is a metabolite of the substance 4-[2-Chloro-4-(trifluoromethyl)phenoxy-2-fluorobenzenamine 4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluoroaniline Not in list C13H8ClF4NO Clc2cc(ccc2Oc1ccc(N)c(F)c1)C(F)(F)F InChI=1/C13H8ClF4NO/c14-9-5-7(13(16,17)18)1-4-12(9)20-8-2-3-11(19)10(15)6-8/h1-6H,19H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Positive RMS: France Flufenoxuron 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron 14Mar2011 2011 doi:10.2903/j.efsa.2011.2088
+Flufenoxuron 417-680-3 101463-69-8 single chemical entity Component is a metabolite of the substance 4-[2-Chloro-4-(trifluoromethyl)phenoxy-2-fluorobenzenamine 4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluoroaniline Not in list C13H8ClF4NO Clc2cc(ccc2Oc1ccc(N)c(F)c1)C(F)(F)F InChI=1/C13H8ClF4NO/c14-9-5-7(13(16,17)18)1-4-12(9)20-8-2-3-11(19)10(15)6-8/h1-6H,19H2 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: France Flufenoxuron 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron 14Mar2011 2011 doi:10.2903/j.efsa.2011.2088
+Flufenoxuron 417-680-3 101463-69-8 single chemical entity Component is a metabolite of the substance 4-[2-Chloro-4-(trifluoromethyl)phenoxy-2-fluorobenzenamine 4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluoroaniline Not in list C13H8ClF4NO Clc2cc(ccc2Oc1ccc(N)c(F)c1)C(F)(F)F InChI=1/C13H8ClF4NO/c14-9-5-7(13(16,17)18)1-4-12(9)20-8-2-3-11(19)10(15)6-8/h1-6H,19H2 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: France Flufenoxuron 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron 14Mar2011 2011 doi:10.2903/j.efsa.2011.2088
+Flufenoxuron 417-680-3 101463-69-8 single chemical entity Component is a metabolite of the substance 4-[2-Chloro-4-(trifluoromethyl)phenoxy-2-fluorobenzenamine 4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluoroaniline Not in list C13H8ClF4NO Clc2cc(ccc2Oc1ccc(N)c(F)c1)C(F)(F)F InChI=1/C13H8ClF4NO/c14-9-5-7(13(16,17)18)1-4-12(9)20-8-2-3-11(19)10(15)6-8/h1-6H,19H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: France Flufenoxuron 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron 14Mar2011 2011 doi:10.2903/j.efsa.2011.2088
+Flufenoxuron 417-680-3 101463-69-8 single chemical entity Component is a metabolite of the substance 4-[2-Chloro-4-(trifluoromethyl)phenoxy-2-fluorobenzenamine 4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluoroaniline Not in list C13H8ClF4NO Clc2cc(ccc2Oc1ccc(N)c(F)c1)C(F)(F)F InChI=1/C13H8ClF4NO/c14-9-5-7(13(16,17)18)1-4-12(9)20-8-2-3-11(19)10(15)6-8/h1-6H,19H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: France Flufenoxuron 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron 14Mar2011 2011 doi:10.2903/j.efsa.2011.2088
+Flufenoxuron 417-680-3 101463-69-8 single chemical entity Component is a metabolite of the substance 4-[2-Chloro-4-(trifluoromethyl)phenoxy-2-fluorobenzenamine 4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluoroaniline Not in list C13H8ClF4NO Clc2cc(ccc2Oc1ccc(N)c(F)c1)C(F)(F)F InChI=1/C13H8ClF4NO/c14-9-5-7(13(16,17)18)1-4-12(9)20-8-2-3-11(19)10(15)6-8/h1-6H,19H2 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair in vitro mammalian cell transformation assay in vitro No guideline available Not reported Not applicable Acceptable Hamster (as animal) embryo cells Not reported yes, concurrent vehicle without Negative RMS: France Flufenoxuron 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron 14Mar2011 2011 doi:10.2903/j.efsa.2011.2088
+Flufenoxuron 417-680-3 101463-69-8 single chemical entity Component is a metabolite of the substance 4-[2-Chloro-4-(trifluoromethyl)phenoxy-2-fluorobenzenamine 4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluoroaniline Not in list C13H8ClF4NO Clc2cc(ccc2Oc1ccc(N)c(F)c1)C(F)(F)F InChI=1/C13H8ClF4NO/c14-9-5-7(13(16,17)18)1-4-12(9)20-8-2-3-11(19)10(15)6-8/h1-6H,19H2 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Wistar 3 Male oral: unspecified 14.0000000000 h yes, concurrent vehicle not applicable Negative RMS: France Flufenoxuron 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron 14Mar2011 2011 doi:10.2903/j.efsa.2011.2088
+Flufenoxuron 417-680-3 101463-69-8 single chemical entity Component is a metabolite of the substance 4-[2-Chloro-4-(trifluoromethyl)phenoxy-2-fluorobenzenamine 4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluoroaniline Not in list C13H8ClF4NO Clc2cc(ccc2Oc1ccc(N)c(F)c1)C(F)(F)F InChI=1/C13H8ClF4NO/c14-9-5-7(13(16,17)18)1-4-12(9)20-8-2-3-11(19)10(15)6-8/h1-6H,19H2 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Wistar 3 Male oral: unspecified 3.0000000000 h yes, concurrent vehicle not applicable Negative RMS: France Flufenoxuron 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron 14Mar2011 2011 doi:10.2903/j.efsa.2011.2088
+Fluometuron 218-500-4 2164-17-2 single chemical entity Component is identical to the substance Fluometuron 218-500-4 2164-17-2 1,1-dimethyl-3-[3-(trifluoromethyl)phenyl]urea Fluometuron C10H11F3N2O CN(C)C(=O)Nc1cccc(c1)C(F)(F)F InChI=1/C10H11F3N2O/c1-15(2)9(16)14-8-5-3-4-7(6-8)10(11,12)13/h3-6H,1-2H3,(H,14,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Greece Fluometuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron 13Jan2011 2011 doi:10.2903/j.efsa.2011.1958
+Fluometuron 218-500-4 2164-17-2 single chemical entity Component is identical to the substance Fluometuron 218-500-4 2164-17-2 1,1-dimethyl-3-[3-(trifluoromethyl)phenyl]urea Fluometuron C10H11F3N2O CN(C)C(=O)Nc1cccc(c1)C(F)(F)F InChI=1/C10H11F3N2O/c1-15(2)9(16)14-8-5-3-4-7(6-8)10(11,12)13/h3-6H,1-2H3,(H,14,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Greece Fluometuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron 13Jan2011 2011 doi:10.2903/j.efsa.2011.1958
+Fluometuron 218-500-4 2164-17-2 single chemical entity Component is identical to the substance Fluometuron 218-500-4 2164-17-2 1,1-dimethyl-3-[3-(trifluoromethyl)phenyl]urea Fluometuron C10H11F3N2O CN(C)C(=O)Nc1cccc(c1)C(F)(F)F InChI=1/C10H11F3N2O/c1-15(2)9(16)14-8-5-3-4-7(6-8)10(11,12)13/h3-6H,1-2H3,(H,14,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Greece Fluometuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron 13Jan2011 2011 doi:10.2903/j.efsa.2011.1958
+Fluometuron 218-500-4 2164-17-2 single chemical entity Component is identical to the substance Fluometuron 218-500-4 2164-17-2 1,1-dimethyl-3-[3-(trifluoromethyl)phenyl]urea Fluometuron C10H11F3N2O CN(C)C(=O)Nc1cccc(c1)C(F)(F)F InChI=1/C10H11F3N2O/c1-15(2)9(16)14-8-5-3-4-7(6-8)10(11,12)13/h3-6H,1-2H3,(H,14,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Greece Fluometuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron 13Jan2011 2011 doi:10.2903/j.efsa.2011.1958
+Fluometuron 218-500-4 2164-17-2 single chemical entity Component is identical to the substance Fluometuron 218-500-4 2164-17-2 1,1-dimethyl-3-[3-(trifluoromethyl)phenyl]urea Fluometuron C10H11F3N2O CN(C)C(=O)Nc1cccc(c1)C(F)(F)F InChI=1/C10H11F3N2O/c1-15(2)9(16)14-8-5-3-4-7(6-8)10(11,12)13/h3-6H,1-2H3,(H,14,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Greece Fluometuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron 13Jan2011 2011 doi:10.2903/j.efsa.2011.1958
+Fluometuron 218-500-4 2164-17-2 single chemical entity Component is identical to the substance Fluometuron 218-500-4 2164-17-2 1,1-dimethyl-3-[3-(trifluoromethyl)phenyl]urea Fluometuron C10H11F3N2O CN(C)C(=O)Nc1cccc(c1)C(F)(F)F InChI=1/C10H11F3N2O/c1-15(2)9(16)14-8-5-3-4-7(6-8)10(11,12)13/h3-6H,1-2H3,(H,14,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Greece Fluometuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron 13Jan2011 2011 doi:10.2903/j.efsa.2011.1958
+Fluometuron 218-500-4 2164-17-2 single chemical entity Component is identical to the substance Fluometuron 218-500-4 2164-17-2 1,1-dimethyl-3-[3-(trifluoromethyl)phenyl]urea Fluometuron C10H11F3N2O CN(C)C(=O)Nc1cccc(c1)C(F)(F)F InChI=1/C10H11F3N2O/c1-15(2)9(16)14-8-5-3-4-7(6-8)10(11,12)13/h3-6H,1-2H3,(H,14,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Greece Fluometuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron 13Jan2011 2011 doi:10.2903/j.efsa.2011.1958
+Fluometuron 218-500-4 2164-17-2 single chemical entity Component is identical to the substance Fluometuron 218-500-4 2164-17-2 1,1-dimethyl-3-[3-(trifluoromethyl)phenyl]urea Fluometuron C10H11F3N2O CN(C)C(=O)Nc1cccc(c1)C(F)(F)F InChI=1/C10H11F3N2O/c1-15(2)9(16)14-8-5-3-4-7(6-8)10(11,12)13/h3-6H,1-2H3,(H,14,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Greece Fluometuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron 13Jan2011 2011 doi:10.2903/j.efsa.2011.1958
+Fluometuron 218-500-4 2164-17-2 single chemical entity Component is identical to the substance Fluometuron 218-500-4 2164-17-2 1,1-dimethyl-3-[3-(trifluoromethyl)phenyl]urea Fluometuron C10H11F3N2O CN(C)C(=O)Nc1cccc(c1)C(F)(F)F InChI=1/C10H11F3N2O/c1-15(2)9(16)14-8-5-3-4-7(6-8)10(11,12)13/h3-6H,1-2H3,(H,14,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Greece Fluometuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron 13Jan2011 2011 doi:10.2903/j.efsa.2011.1958
+Fluometuron 218-500-4 2164-17-2 single chemical entity Component is identical to the substance Fluometuron 218-500-4 2164-17-2 1,1-dimethyl-3-[3-(trifluoromethyl)phenyl]urea Fluometuron C10H11F3N2O CN(C)C(=O)Nc1cccc(c1)C(F)(F)F InChI=1/C10H11F3N2O/c1-15(2)9(16)14-8-5-3-4-7(6-8)10(11,12)13/h3-6H,1-2H3,(H,14,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Greece Fluometuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron 13Jan2011 2011 doi:10.2903/j.efsa.2011.1958
+Fluometuron 218-500-4 2164-17-2 single chemical entity Component is identical to the substance Fluometuron 218-500-4 2164-17-2 1,1-dimethyl-3-[3-(trifluoromethyl)phenyl]urea Fluometuron C10H11F3N2O CN(C)C(=O)Nc1cccc(c1)C(F)(F)F InChI=1/C10H11F3N2O/c1-15(2)9(16)14-8-5-3-4-7(6-8)10(11,12)13/h3-6H,1-2H3,(H,14,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Greece Fluometuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron 13Jan2011 2011 doi:10.2903/j.efsa.2011.1958
+Fluometuron 218-500-4 2164-17-2 single chemical entity Component is identical to the substance Fluometuron 218-500-4 2164-17-2 1,1-dimethyl-3-[3-(trifluoromethyl)phenyl]urea Fluometuron C10H11F3N2O CN(C)C(=O)Nc1cccc(c1)C(F)(F)F InChI=1/C10H11F3N2O/c1-15(2)9(16)14-8-5-3-4-7(6-8)10(11,12)13/h3-6H,1-2H3,(H,14,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Greece Fluometuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron 13Jan2011 2011 doi:10.2903/j.efsa.2011.1958
+Fluometuron 218-500-4 2164-17-2 single chemical entity Component is identical to the substance Fluometuron 218-500-4 2164-17-2 1,1-dimethyl-3-[3-(trifluoromethyl)phenyl]urea Fluometuron C10H11F3N2O CN(C)C(=O)Nc1cccc(c1)C(F)(F)F InChI=1/C10H11F3N2O/c1-15(2)9(16)14-8-5-3-4-7(6-8)10(11,12)13/h3-6H,1-2H3,(H,14,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Greece Fluometuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron 13Jan2011 2011 doi:10.2903/j.efsa.2011.1958
+Fluometuron 218-500-4 2164-17-2 single chemical entity Component is identical to the substance Fluometuron 218-500-4 2164-17-2 1,1-dimethyl-3-[3-(trifluoromethyl)phenyl]urea Fluometuron C10H11F3N2O CN(C)C(=O)Nc1cccc(c1)C(F)(F)F InChI=1/C10H11F3N2O/c1-15(2)9(16)14-8-5-3-4-7(6-8)10(11,12)13/h3-6H,1-2H3,(H,14,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Greece Fluometuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron 13Jan2011 2011 doi:10.2903/j.efsa.2011.1958
+Fluometuron 218-500-4 2164-17-2 single chemical entity Component is identical to the substance Fluometuron 218-500-4 2164-17-2 1,1-dimethyl-3-[3-(trifluoromethyl)phenyl]urea Fluometuron C10H11F3N2O CN(C)C(=O)Nc1cccc(c1)C(F)(F)F InChI=1/C10H11F3N2O/c1-15(2)9(16)14-8-5-3-4-7(6-8)10(11,12)13/h3-6H,1-2H3,(H,14,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Greece Fluometuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron 13Jan2011 2011 doi:10.2903/j.efsa.2011.1958
+Fluometuron 218-500-4 2164-17-2 single chemical entity Component is identical to the substance Fluometuron 218-500-4 2164-17-2 1,1-dimethyl-3-[3-(trifluoromethyl)phenyl]urea Fluometuron C10H11F3N2O CN(C)C(=O)Nc1cccc(c1)C(F)(F)F InChI=1/C10H11F3N2O/c1-15(2)9(16)14-8-5-3-4-7(6-8)10(11,12)13/h3-6H,1-2H3,(H,14,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle without Negative RMS: Greece Fluometuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron 13Jan2011 2011 doi:10.2903/j.efsa.2011.1958
+Fluometuron 218-500-4 2164-17-2 single chemical entity Component is identical to the substance Fluometuron 218-500-4 2164-17-2 1,1-dimethyl-3-[3-(trifluoromethyl)phenyl]urea Fluometuron C10H11F3N2O CN(C)C(=O)Nc1cccc(c1)C(F)(F)F InChI=1/C10H11F3N2O/c1-15(2)9(16)14-8-5-3-4-7(6-8)10(11,12)13/h3-6H,1-2H3,(H,14,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Greece Fluometuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron 13Jan2011 2011 doi:10.2903/j.efsa.2011.1958
+Fluometuron 218-500-4 2164-17-2 single chemical entity Component is identical to the substance Fluometuron 218-500-4 2164-17-2 1,1-dimethyl-3-[3-(trifluoromethyl)phenyl]urea Fluometuron C10H11F3N2O CN(C)C(=O)Nc1cccc(c1)C(F)(F)F InChI=1/C10H11F3N2O/c1-15(2)9(16)14-8-5-3-4-7(6-8)10(11,12)13/h3-6H,1-2H3,(H,14,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle with Negative RMS: Greece Fluometuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron 13Jan2011 2011 doi:10.2903/j.efsa.2011.1958
+Fluometuron 218-500-4 2164-17-2 single chemical entity Component is identical to the substance Fluometuron 218-500-4 2164-17-2 1,1-dimethyl-3-[3-(trifluoromethyl)phenyl]urea Fluometuron C10H11F3N2O CN(C)C(=O)Nc1cccc(c1)C(F)(F)F InChI=1/C10H11F3N2O/c1-15(2)9(16)14-8-5-3-4-7(6-8)10(11,12)13/h3-6H,1-2H3,(H,14,16) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Greece Fluometuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron 13Jan2011 2011 doi:10.2903/j.efsa.2011.1958
+Fluometuron 218-500-4 2164-17-2 single chemical entity Component is identical to the substance Fluometuron 218-500-4 2164-17-2 1,1-dimethyl-3-[3-(trifluoromethyl)phenyl]urea Fluometuron C10H11F3N2O CN(C)C(=O)Nc1cccc(c1)C(F)(F)F InChI=1/C10H11F3N2O/c1-15(2)9(16)14-8-5-3-4-7(6-8)10(11,12)13/h3-6H,1-2H3,(H,14,16) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Greece Fluometuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron 13Jan2011 2011 doi:10.2903/j.efsa.2011.1958
+Fluometuron 218-500-4 2164-17-2 single chemical entity Component is identical to the substance Fluometuron 218-500-4 2164-17-2 1,1-dimethyl-3-[3-(trifluoromethyl)phenyl]urea Fluometuron C10H11F3N2O CN(C)C(=O)Nc1cccc(c1)C(F)(F)F InChI=1/C10H11F3N2O/c1-15(2)9(16)14-8-5-3-4-7(6-8)10(11,12)13/h3-6H,1-2H3,(H,14,16) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Positive RMS: Greece Fluometuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron 13Jan2011 2011 doi:10.2903/j.efsa.2011.1958
+Fluometuron 218-500-4 2164-17-2 single chemical entity Component is identical to the substance Fluometuron 218-500-4 2164-17-2 1,1-dimethyl-3-[3-(trifluoromethyl)phenyl]urea Fluometuron C10H11F3N2O CN(C)C(=O)Nc1cccc(c1)C(F)(F)F InChI=1/C10H11F3N2O/c1-15(2)9(16)14-8-5-3-4-7(6-8)10(11,12)13/h3-6H,1-2H3,(H,14,16) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Positive RMS: Greece Fluometuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron 13Jan2011 2011 doi:10.2903/j.efsa.2011.1958
+Fluometuron 218-500-4 2164-17-2 single chemical entity Component is identical to the substance Fluometuron 218-500-4 2164-17-2 1,1-dimethyl-3-[3-(trifluoromethyl)phenyl]urea Fluometuron C10H11F3N2O CN(C)C(=O)Nc1cccc(c1)C(F)(F)F InChI=1/C10H11F3N2O/c1-15(2)9(16)14-8-5-3-4-7(6-8)10(11,12)13/h3-6H,1-2H3,(H,14,16) organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Rat (as animal) hepatocytes Not reported yes without Negative RMS: Greece Fluometuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron 13Jan2011 2011 doi:10.2903/j.efsa.2011.1958
+Fluometuron 218-500-4 2164-17-2 single chemical entity Component is identical to the substance Fluometuron 218-500-4 2164-17-2 1,1-dimethyl-3-[3-(trifluoromethyl)phenyl]urea Fluometuron C10H11F3N2O CN(C)C(=O)Nc1cccc(c1)C(F)(F)F InChI=1/C10H11F3N2O/c1-15(2)9(16)14-8-5-3-4-7(6-8)10(11,12)13/h3-6H,1-2H3,(H,14,16) organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Greece Fluometuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron 13Jan2011 2011 doi:10.2903/j.efsa.2011.1958
+Fluometuron 218-500-4 2164-17-2 single chemical entity Component is identical to the substance Fluometuron 218-500-4 2164-17-2 1,1-dimethyl-3-[3-(trifluoromethyl)phenyl]urea Fluometuron C10H11F3N2O CN(C)C(=O)Nc1cccc(c1)C(F)(F)F InChI=1/C10H11F3N2O/c1-15(2)9(16)14-8-5-3-4-7(6-8)10(11,12)13/h3-6H,1-2H3,(H,14,16) organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Human (as organism) fibroblast Not reported yes without Negative RMS: Greece Fluometuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron 13Jan2011 2011 doi:10.2903/j.efsa.2011.1958
+Fluometuron 218-500-4 2164-17-2 single chemical entity Component is identical to the substance Fluometuron 218-500-4 2164-17-2 1,1-dimethyl-3-[3-(trifluoromethyl)phenyl]urea Fluometuron C10H11F3N2O CN(C)C(=O)Nc1cccc(c1)C(F)(F)F InChI=1/C10H11F3N2O/c1-15(2)9(16)14-8-5-3-4-7(6-8)10(11,12)13/h3-6H,1-2H3,(H,14,16) organic compound Other Other chromosome aberration other in vivo No guideline available Not reported Not applicable Acceptable Hamster (as animal) Chinese 12 Male/Female oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Greece Fluometuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron 13Jan2011 2011 doi:10.2903/j.efsa.2011.1958
+Fluometuron 218-500-4 2164-17-2 single chemical entity Component is identical to the substance Fluometuron 218-500-4 2164-17-2 1,1-dimethyl-3-[3-(trifluoromethyl)phenyl]urea Fluometuron C10H11F3N2O CN(C)C(=O)Nc1cccc(c1)C(F)(F)F InChI=1/C10H11F3N2O/c1-15(2)9(16)14-8-5-3-4-7(6-8)10(11,12)13/h3-6H,1-2H3,(H,14,16) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes not applicable Negative indirect evidence-systemic toxicity RMS: Greece Fluometuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron 13Jan2011 2011 doi:10.2903/j.efsa.2011.1958
+Fluometuron 218-500-4 2164-17-2 single chemical entity Component is identical to the substance Fluometuron 218-500-4 2164-17-2 1,1-dimethyl-3-[3-(trifluoromethyl)phenyl]urea Fluometuron C10H11F3N2O CN(C)C(=O)Nc1cccc(c1)C(F)(F)F InChI=1/C10H11F3N2O/c1-15(2)9(16)14-8-5-3-4-7(6-8)10(11,12)13/h3-6H,1-2H3,(H,14,16) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 48.0000000000 h yes not applicable Negative indirect evidence-systemic toxicity RMS: Greece Fluometuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron 13Jan2011 2011 doi:10.2903/j.efsa.2011.1958
+Fluometuron 218-500-4 2164-17-2 single chemical entity Component is a metabolite of the substance Desmethyl-fluometuron 3032-40-4 1-methyl-3-[3-(trifluoromethyl)phenyl]urea Fluometuron metabolite (CGA 41686) C9H9F3N2O CNC(=O)NC1=CC=CC(=C1)C(F)(F)F InChI=1S/C9H9F3N2O/c1-13-8(15)14-7-4-2-3-6(5-7)9(10,11)12/h2-5H,1H3,(H2,13,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Greece Fluometuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron 13Jan2011 2011 doi:10.2903/j.efsa.2011.1958
+Fluometuron 218-500-4 2164-17-2 single chemical entity Component is a metabolite of the substance Desmethyl-fluometuron 3032-40-4 1-methyl-3-[3-(trifluoromethyl)phenyl]urea Fluometuron metabolite (CGA 41686) C9H9F3N2O CNC(=O)NC1=CC=CC(=C1)C(F)(F)F InChI=1S/C9H9F3N2O/c1-13-8(15)14-7-4-2-3-6(5-7)9(10,11)12/h2-5H,1H3,(H2,13,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Greece Fluometuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron 13Jan2011 2011 doi:10.2903/j.efsa.2011.1958
+Fluometuron 218-500-4 2164-17-2 single chemical entity Component is a metabolite of the substance Desmethyl-fluometuron 3032-40-4 1-methyl-3-[3-(trifluoromethyl)phenyl]urea Fluometuron metabolite (CGA 41686) C9H9F3N2O CNC(=O)NC1=CC=CC(=C1)C(F)(F)F InChI=1S/C9H9F3N2O/c1-13-8(15)14-7-4-2-3-6(5-7)9(10,11)12/h2-5H,1H3,(H2,13,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Greece Fluometuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron 13Jan2011 2011 doi:10.2903/j.efsa.2011.1958
+Fluometuron 218-500-4 2164-17-2 single chemical entity Component is a metabolite of the substance Desmethyl-fluometuron 3032-40-4 1-methyl-3-[3-(trifluoromethyl)phenyl]urea Fluometuron metabolite (CGA 41686) C9H9F3N2O CNC(=O)NC1=CC=CC(=C1)C(F)(F)F InChI=1S/C9H9F3N2O/c1-13-8(15)14-7-4-2-3-6(5-7)9(10,11)12/h2-5H,1H3,(H2,13,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Greece Fluometuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron 13Jan2011 2011 doi:10.2903/j.efsa.2011.1958
+Fluometuron 218-500-4 2164-17-2 single chemical entity Component is a metabolite of the substance Desmethyl-fluometuron 3032-40-4 1-methyl-3-[3-(trifluoromethyl)phenyl]urea Fluometuron metabolite (CGA 41686) C9H9F3N2O CNC(=O)NC1=CC=CC(=C1)C(F)(F)F InChI=1S/C9H9F3N2O/c1-13-8(15)14-7-4-2-3-6(5-7)9(10,11)12/h2-5H,1H3,(H2,13,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle without Negative RMS: Greece Fluometuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron 13Jan2011 2011 doi:10.2903/j.efsa.2011.1958
+Fluometuron 218-500-4 2164-17-2 single chemical entity Component is a metabolite of the substance Desmethyl-fluometuron 3032-40-4 1-methyl-3-[3-(trifluoromethyl)phenyl]urea Fluometuron metabolite (CGA 41686) C9H9F3N2O CNC(=O)NC1=CC=CC(=C1)C(F)(F)F InChI=1S/C9H9F3N2O/c1-13-8(15)14-7-4-2-3-6(5-7)9(10,11)12/h2-5H,1H3,(H2,13,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) CM891 Not reported yes, concurrent vehicle without Negative RMS: Greece Fluometuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron 13Jan2011 2011 doi:10.2903/j.efsa.2011.1958
+Fluometuron 218-500-4 2164-17-2 single chemical entity Component is a metabolite of the substance Desmethyl-fluometuron 3032-40-4 1-methyl-3-[3-(trifluoromethyl)phenyl]urea Fluometuron metabolite (CGA 41686) C9H9F3N2O CNC(=O)NC1=CC=CC(=C1)C(F)(F)F InChI=1S/C9H9F3N2O/c1-13-8(15)14-7-4-2-3-6(5-7)9(10,11)12/h2-5H,1H3,(H2,13,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Greece Fluometuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron 13Jan2011 2011 doi:10.2903/j.efsa.2011.1958
+Fluometuron 218-500-4 2164-17-2 single chemical entity Component is a metabolite of the substance Desmethyl-fluometuron 3032-40-4 1-methyl-3-[3-(trifluoromethyl)phenyl]urea Fluometuron metabolite (CGA 41686) C9H9F3N2O CNC(=O)NC1=CC=CC(=C1)C(F)(F)F InChI=1S/C9H9F3N2O/c1-13-8(15)14-7-4-2-3-6(5-7)9(10,11)12/h2-5H,1H3,(H2,13,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Greece Fluometuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron 13Jan2011 2011 doi:10.2903/j.efsa.2011.1958
+Fluometuron 218-500-4 2164-17-2 single chemical entity Component is a metabolite of the substance Desmethyl-fluometuron 3032-40-4 1-methyl-3-[3-(trifluoromethyl)phenyl]urea Fluometuron metabolite (CGA 41686) C9H9F3N2O CNC(=O)NC1=CC=CC(=C1)C(F)(F)F InChI=1S/C9H9F3N2O/c1-13-8(15)14-7-4-2-3-6(5-7)9(10,11)12/h2-5H,1H3,(H2,13,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle with Negative RMS: Greece Fluometuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron 13Jan2011 2011 doi:10.2903/j.efsa.2011.1958
+Fluometuron 218-500-4 2164-17-2 single chemical entity Component is a metabolite of the substance Desmethyl-fluometuron 3032-40-4 1-methyl-3-[3-(trifluoromethyl)phenyl]urea Fluometuron metabolite (CGA 41686) C9H9F3N2O CNC(=O)NC1=CC=CC(=C1)C(F)(F)F InChI=1S/C9H9F3N2O/c1-13-8(15)14-7-4-2-3-6(5-7)9(10,11)12/h2-5H,1H3,(H2,13,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Greece Fluometuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron 13Jan2011 2011 doi:10.2903/j.efsa.2011.1958
+Fluometuron 218-500-4 2164-17-2 single chemical entity Component is a metabolite of the substance Desmethyl-fluometuron 3032-40-4 1-methyl-3-[3-(trifluoromethyl)phenyl]urea Fluometuron metabolite (CGA 41686) C9H9F3N2O CNC(=O)NC1=CC=CC(=C1)C(F)(F)F InChI=1S/C9H9F3N2O/c1-13-8(15)14-7-4-2-3-6(5-7)9(10,11)12/h2-5H,1H3,(H2,13,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Greece Fluometuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron 13Jan2011 2011 doi:10.2903/j.efsa.2011.1958
+Fluometuron 218-500-4 2164-17-2 single chemical entity Component is a metabolite of the substance Desmethyl-fluometuron 3032-40-4 1-methyl-3-[3-(trifluoromethyl)phenyl]urea Fluometuron metabolite (CGA 41686) C9H9F3N2O CNC(=O)NC1=CC=CC(=C1)C(F)(F)F InChI=1S/C9H9F3N2O/c1-13-8(15)14-7-4-2-3-6(5-7)9(10,11)12/h2-5H,1H3,(H2,13,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) CM891 Not reported yes, concurrent vehicle with Negative RMS: Greece Fluometuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron 13Jan2011 2011 doi:10.2903/j.efsa.2011.1958
+Fluometuron 218-500-4 2164-17-2 single chemical entity Component is a metabolite of the substance Desmethyl-fluometuron 3032-40-4 1-methyl-3-[3-(trifluoromethyl)phenyl]urea Fluometuron metabolite (CGA 41686) C9H9F3N2O CNC(=O)NC1=CC=CC(=C1)C(F)(F)F InChI=1S/C9H9F3N2O/c1-13-8(15)14-7-4-2-3-6(5-7)9(10,11)12/h2-5H,1H3,(H2,13,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Positive no information RMS: Greece Fluometuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron 13Jan2011 2011 doi:10.2903/j.efsa.2011.1958
+Fluometuron 218-500-4 2164-17-2 single chemical entity Component is a metabolite of the substance Desmethyl-fluometuron 3032-40-4 1-methyl-3-[3-(trifluoromethyl)phenyl]urea Fluometuron metabolite (CGA 41686) C9H9F3N2O CNC(=O)NC1=CC=CC(=C1)C(F)(F)F InChI=1S/C9H9F3N2O/c1-13-8(15)14-7-4-2-3-6(5-7)9(10,11)12/h2-5H,1H3,(H2,13,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Positive no information RMS: Greece Fluometuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron 13Jan2011 2011 doi:10.2903/j.efsa.2011.1958
+Fluometuron 218-500-4 2164-17-2 single chemical entity Component is a metabolite of the substance Desmethyl-fluometuron 3032-40-4 1-methyl-3-[3-(trifluoromethyl)phenyl]urea Fluometuron metabolite (CGA 41686) C9H9F3N2O CNC(=O)NC1=CC=CC(=C1)C(F)(F)F InChI=1S/C9H9F3N2O/c1-13-8(15)14-7-4-2-3-6(5-7)9(10,11)12/h2-5H,1H3,(H2,13,14,15) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent no treatment without Negative RMS: Greece Fluometuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron 13Jan2011 2011 doi:10.2903/j.efsa.2011.1958
+Fluometuron 218-500-4 2164-17-2 single chemical entity Component is a metabolite of the substance Desmethyl-fluometuron 3032-40-4 1-methyl-3-[3-(trifluoromethyl)phenyl]urea Fluometuron metabolite (CGA 41686) C9H9F3N2O CNC(=O)NC1=CC=CC(=C1)C(F)(F)F InChI=1S/C9H9F3N2O/c1-13-8(15)14-7-4-2-3-6(5-7)9(10,11)12/h2-5H,1H3,(H2,13,14,15) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent no treatment with Positive RMS: Greece Fluometuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron 13Jan2011 2011 doi:10.2903/j.efsa.2011.1958
+Fluometuron 218-500-4 2164-17-2 single chemical entity Component is a metabolite of the substance Desmethyl-fluometuron 3032-40-4 1-methyl-3-[3-(trifluoromethyl)phenyl]urea Fluometuron metabolite (CGA 41686) C9H9F3N2O CNC(=O)NC1=CC=CC(=C1)C(F)(F)F InChI=1S/C9H9F3N2O/c1-13-8(15)14-7-4-2-3-6(5-7)9(10,11)12/h2-5H,1H3,(H2,13,14,15) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 7 Male oral: gavage 48.0000000000 h yes not applicable Negative indirect evidence-systemic toxicity RMS: Greece Fluometuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron 13Jan2011 2011 doi:10.2903/j.efsa.2011.1958
+Fluometuron 218-500-4 2164-17-2 single chemical entity Component is a metabolite of the substance Desmethyl-fluometuron 3032-40-4 1-methyl-3-[3-(trifluoromethyl)phenyl]urea Fluometuron metabolite (CGA 41686) C9H9F3N2O CNC(=O)NC1=CC=CC(=C1)C(F)(F)F InChI=1S/C9H9F3N2O/c1-13-8(15)14-7-4-2-3-6(5-7)9(10,11)12/h2-5H,1H3,(H2,13,14,15) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 7 Male oral: gavage 24.0000000000 h yes not applicable Negative indirect evidence-systemic toxicity RMS: Greece Fluometuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron 13Jan2011 2011 doi:10.2903/j.efsa.2011.1958
+Fluometuron 218-500-4 2164-17-2 single chemical entity Component is a metabolite of the substance Desmethyl-fluometuron 3032-40-4 1-methyl-3-[3-(trifluoromethyl)phenyl]urea Fluometuron metabolite (CGA 41686) C9H9F3N2O CNC(=O)NC1=CC=CC(=C1)C(F)(F)F InChI=1S/C9H9F3N2O/c1-13-8(15)14-7-4-2-3-6(5-7)9(10,11)12/h2-5H,1H3,(H2,13,14,15) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo Equivalent or similar to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) Yes Acceptable Rat (as animal) Sprague-Dawley 10 Male oral: gavage 2.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Greece Fluometuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron 13Jan2011 2011 doi:10.2903/j.efsa.2011.1958
+Fluometuron 218-500-4 2164-17-2 single chemical entity Component is a metabolite of the substance Desmethyl-fluometuron 3032-40-4 1-methyl-3-[3-(trifluoromethyl)phenyl]urea Fluometuron metabolite (CGA 41686) C9H9F3N2O CNC(=O)NC1=CC=CC(=C1)C(F)(F)F InChI=1S/C9H9F3N2O/c1-13-8(15)14-7-4-2-3-6(5-7)9(10,11)12/h2-5H,1H3,(H2,13,14,15) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo Equivalent or similar to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) Yes Acceptable Rat (as animal) Sprague-Dawley 10 Male oral: gavage 14.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Greece Fluometuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron 13Jan2011 2011 doi:10.2903/j.efsa.2011.1958
+Cypermethrin 257-842-9 52315-07-8 single chemical entity Component is part of a group assessment Alpha-Cypermethrin 614-054-3 67375-30-8 [(R)-cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate Not in list C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m0/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium Cypermethrin 1999 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Cypermethrin 257-842-9 52315-07-8 single chemical entity Component is part of a group assessment Alpha-Cypermethrin 614-054-3 67375-30-8 [(R)-cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate Not in list C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m0/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle with Negative RMS: Belgium Cypermethrin 1999 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Cypermethrin 257-842-9 52315-07-8 single chemical entity Component is part of a group assessment Alpha-Cypermethrin 614-054-3 67375-30-8 [(R)-cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate Not in list C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m0/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium Cypermethrin 1999 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Cypermethrin 257-842-9 52315-07-8 single chemical entity Component is part of a group assessment Alpha-Cypermethrin 614-054-3 67375-30-8 [(R)-cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate Not in list C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m0/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium Cypermethrin 1999 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Cypermethrin 257-842-9 52315-07-8 single chemical entity Component is part of a group assessment Alpha-Cypermethrin 614-054-3 67375-30-8 [(R)-cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate Not in list C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m0/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium Cypermethrin 1999 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Cypermethrin 257-842-9 52315-07-8 single chemical entity Component is part of a group assessment Alpha-Cypermethrin 614-054-3 67375-30-8 [(R)-cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate Not in list C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m0/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium Cypermethrin 1999 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Cypermethrin 257-842-9 52315-07-8 single chemical entity Component is part of a group assessment Alpha-Cypermethrin 614-054-3 67375-30-8 [(R)-cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate Not in list C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m0/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Belgium Cypermethrin 1999 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Cypermethrin 257-842-9 52315-07-8 single chemical entity Component is part of a group assessment Alpha-Cypermethrin 614-054-3 67375-30-8 [(R)-cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate Not in list C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m0/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium Cypermethrin 1999 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Cypermethrin 257-842-9 52315-07-8 single chemical entity Component is part of a group assessment Alpha-Cypermethrin 614-054-3 67375-30-8 [(R)-cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate Not in list C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m0/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Belgium Cypermethrin 1999 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Cypermethrin 257-842-9 52315-07-8 single chemical entity Component is part of a group assessment Alpha-Cypermethrin 614-054-3 67375-30-8 [(R)-cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate Not in list C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m0/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle without Negative RMS: Belgium Cypermethrin 1999 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Cypermethrin 257-842-9 52315-07-8 single chemical entity Component is part of a group assessment Alpha-Cypermethrin 614-054-3 67375-30-8 [(R)-cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate Not in list C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m0/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium Cypermethrin 1999 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Cypermethrin 257-842-9 52315-07-8 single chemical entity Component is part of a group assessment Alpha-Cypermethrin 614-054-3 67375-30-8 [(R)-cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate Not in list C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m0/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium Cypermethrin 1999 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Cypermethrin 257-842-9 52315-07-8 single chemical entity Component is identical to the substance Cypermethrin 257-842-9 52315-07-8 [cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate Cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro Equivalent or similar to OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay) Yes Acceptable Saccharomyces cerevisiae (as organism) Strain JD1 S. cerevisiae Not reported yes with Negative RMS: Belgium Cypermethrin 1999 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Cypermethrin 257-842-9 52315-07-8 single chemical entity Component is identical to the substance Cypermethrin 257-842-9 52315-07-8 [cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate Cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair in vitro mammalian cell transformation assay in vitro No guideline available Not reported Not applicable Acceptable Hamster (as animal) kidney cells Not reported no data no data Negative RMS: Belgium Cypermethrin 1999 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Cypermethrin 257-842-9 52315-07-8 single chemical entity Component is identical to the substance Cypermethrin 257-842-9 52315-07-8 [cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate Cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Rat (as animal) hepatocytes Not reported no data with Negative RMS: Belgium Cypermethrin 1999 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Cypermethrin 257-842-9 52315-07-8 single chemical entity Component is identical to the substance Cypermethrin 257-842-9 52315-07-8 [cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate Cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro Equivalent or similar to OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay) Yes Acceptable Saccharomyces cerevisiae (as organism) Strain JD1 S. cerevisiae Not reported yes without Negative RMS: Belgium Cypermethrin 1999 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Cypermethrin 257-842-9 52315-07-8 single chemical entity Component is identical to the substance Cypermethrin 257-842-9 52315-07-8 [cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate Cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro Equivalent or similar to OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay) Yes Acceptable Saccharomyces cerevisiae (as organism) Strain JD1 S. cerevisiae Not reported yes with Negative RMS: Belgium Cypermethrin 1999 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Cypermethrin 257-842-9 52315-07-8 single chemical entity Component is identical to the substance Cypermethrin 257-842-9 52315-07-8 [cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate Cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro Equivalent or similar to OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay) Yes Acceptable Saccharomyces cerevisiae (as organism) Strain JD1 S. cerevisiae Not reported yes without Negative RMS: Belgium Cypermethrin 1999 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Cypermethrin 257-842-9 52315-07-8 single chemical entity Component is part of a group assessment Alpha-Cypermethrin 614-054-3 67375-30-8 [(R)-cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate Not in list C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m0/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Negative no information RMS: Belgium Cypermethrin 1999 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Cypermethrin 257-842-9 52315-07-8 single chemical entity Component is part of a group assessment Alpha-Cypermethrin 614-054-3 67375-30-8 [(R)-cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate Not in list C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m0/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative no information RMS: Belgium Cypermethrin 1999 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Cypermethrin 257-842-9 52315-07-8 single chemical entity Component is part of a group assessment Alpha-Cypermethrin 614-054-3 67375-30-8 [(R)-cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate Not in list C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m0/s1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes without Negative RMS: Belgium Cypermethrin 1999 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Cypermethrin 257-842-9 52315-07-8 single chemical entity Component is part of a group assessment Alpha-Cypermethrin 614-054-3 67375-30-8 [(R)-cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate Not in list C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m0/s1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes with Negative RMS: Belgium Cypermethrin 1999 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Cypermethrin 257-842-9 52315-07-8 single chemical entity Component is part of a group assessment Alpha-Cypermethrin 614-054-3 67375-30-8 [(R)-cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate Not in list C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m0/s1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Swiss 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Belgium Cypermethrin 1999 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Cypermethrin 257-842-9 52315-07-8 single chemical entity Component is part of a group assessment Alpha-Cypermethrin 614-054-3 67375-30-8 [(R)-cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate Not in list C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m0/s1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Swiss 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Belgium Cypermethrin 1999 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Cypermethrin 257-842-9 52315-07-8 single chemical entity Component is part of a group assessment Alpha-Cypermethrin 614-054-3 67375-30-8 [(R)-cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate Not in list C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m0/s1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Swiss 10 Male/Female oral: gavage 72.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Belgium Cypermethrin 1999 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Cypermethrin 257-842-9 52315-07-8 single chemical entity Component is identical to the substance Cypermethrin 257-842-9 52315-07-8 [cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate Cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable Hamster (as animal) Chinese 6 Male/Female oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Belgium Cypermethrin 1999 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Cypermethrin 257-842-9 52315-07-8 single chemical entity Component is part of a group assessment Alpha-Cypermethrin 614-054-3 67375-30-8 [(R)-cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate Not in list C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m0/s1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Rat (as animal) Not reported 12 Male/Female oral: unspecified 24.0000000000 h yes not applicable Negative RMS: Belgium Cypermethrin 1999 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Cypermethrin 257-842-9 52315-07-8 single chemical entity Component is identical to the substance Cypermethrin 257-842-9 52315-07-8 [cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate Cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Hamster (as animal) Chinese 6 Male/Female oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Belgium Cypermethrin 1999 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Cypermethrin 257-842-9 52315-07-8 single chemical entity Component is identical to the substance Cypermethrin 257-842-9 52315-07-8 [cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate Cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Hamster (as animal) Chinese 6 Male/Female oral: unspecified 8.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Belgium Cypermethrin 1999 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Cypermethrin 257-842-9 52315-07-8 single chemical entity Component is identical to the substance Cypermethrin 257-842-9 52315-07-8 [cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate Cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) Yes Acceptable House mouse (as animal) CD-1 12 Male oral: unspecified yes, concurrent vehicle not applicable Negative RMS: Belgium Cypermethrin 1999 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Cypermethrin 257-842-9 52315-07-8 single chemical entity Component is identical to the substance Cypermethrin 257-842-9 52315-07-8 [cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate Cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation other in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) Not reported No data oral: unspecified no data not applicable Negative RMS: Belgium Cypermethrin 1999 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Cypermethrin 257-842-9 52315-07-8 single chemical entity Component is identical to the substance Cypermethrin 257-842-9 52315-07-8 [cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate Cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo Equivalent or similar to OECD Guideline 489 Yes Acceptable Rat (as animal) Not reported Male/Female oral: gavage 16.0000000000 h no data not applicable Negative RMS: Belgium Cypermethrin 1999 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Cypermethrin 257-842-9 52315-07-8 single chemical entity Component is identical to the substance Cypermethrin 257-842-9 52315-07-8 [cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate Cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Belgium Cypermethrin 1999 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Cypermethrin 257-842-9 52315-07-8 single chemical entity Component is identical to the substance Cypermethrin 257-842-9 52315-07-8 [cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate Cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Belgium Cypermethrin 1999 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Cypermethrin 257-842-9 52315-07-8 single chemical entity Component is identical to the substance Cypermethrin 257-842-9 52315-07-8 [cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate Cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No data Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data with Negative RMS: Belgium Cypermethrin 1999 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Cypermethrin 257-842-9 52315-07-8 single chemical entity Component is identical to the substance Cypermethrin 257-842-9 52315-07-8 [cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate Cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Belgium Cypermethrin 1999 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Cypermethrin 257-842-9 52315-07-8 single chemical entity Component is identical to the substance Cypermethrin 257-842-9 52315-07-8 [cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate Cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No data Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data without Negative RMS: Belgium Cypermethrin 1999 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Cypermethrin 257-842-9 52315-07-8 single chemical entity Component is identical to the substance Cypermethrin 257-842-9 52315-07-8 [cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate Cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Belgium Cypermethrin 1999 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Cypermethrin 257-842-9 52315-07-8 single chemical entity Component is identical to the substance Cypermethrin 257-842-9 52315-07-8 [cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate Cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian cell micronucleus test in vitro Equivalent or similar to OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test) No data Acceptable Human (as organism) lymphocytes Not reported yes no data Negative RMS: Belgium Cypermethrin 1999 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Cypermethrin 257-842-9 52315-07-8 single chemical entity Component is identical to the substance Cypermethrin 257-842-9 52315-07-8 [cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate Cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro According to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No Acceptable Human (as organism) lymphocytes Not reported yes not applicable Negative RMS: Belgium Cypermethrin 1999 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Cypermethrin 257-842-9 52315-07-8 single chemical entity Component is identical to the substance Cypermethrin 257-842-9 52315-07-8 [cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate Cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported no data without Negative RMS: Belgium Cypermethrin 1999 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Cypermethrin 257-842-9 52315-07-8 single chemical entity Component is identical to the substance Cypermethrin 257-842-9 52315-07-8 [cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate Cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) Swiss 3 No data intraperitoneal 24.0000000000 h yes, concurrent vehicle not applicable Positive RMS: Belgium Cypermethrin 1999 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Cypermethrin 257-842-9 52315-07-8 single chemical entity Component is identical to the substance Cypermethrin 257-842-9 52315-07-8 [cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate Cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) Swiss 3 No data oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Positive RMS: Belgium Cypermethrin 1999 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Cypermethrin 257-842-9 52315-07-8 single chemical entity Component is identical to the substance Cypermethrin 257-842-9 52315-07-8 [cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate Cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Swiss 3 No data intraperitoneal 6.0000000000 h yes, concurrent vehicle not applicable Positive RMS: Belgium Cypermethrin 1999 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Cypermethrin 257-842-9 52315-07-8 single chemical entity Component is identical to the substance Cypermethrin 257-842-9 52315-07-8 [cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate Cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) Swiss 3 No data intraperitoneal 48.0000000000 h yes, concurrent vehicle not applicable Positive RMS: Belgium Cypermethrin 1999 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Cypermethrin 257-842-9 52315-07-8 single chemical entity Component is identical to the substance Cypermethrin 257-842-9 52315-07-8 [cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate Cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) Swiss 5 No data intraperitoneal 48.0000000000 h yes, concurrent vehicle not applicable Positive RMS: Belgium Cypermethrin 1999 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Cypermethrin 257-842-9 52315-07-8 single chemical entity Component is identical to the substance Cypermethrin 257-842-9 52315-07-8 [cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate Cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) Swiss 6 No data intraperitoneal 24.0000000000 h yes not applicable Positive RMS: Belgium Cypermethrin 1999 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Cypermethrin 257-842-9 52315-07-8 single chemical entity Component is identical to the substance Cypermethrin 257-842-9 52315-07-8 [cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate Cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) Swiss 5 No data intraperitoneal 24.0000000000 h yes, concurrent vehicle not applicable Positive RMS: Belgium Cypermethrin 1999 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Cypermethrin 257-842-9 52315-07-8 single chemical entity Component is identical to the substance Cypermethrin 257-842-9 52315-07-8 [cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate Cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Swiss 3 No data dermal 24.0000000000 h yes not applicable Negative no evidence RMS: Belgium Cypermethrin 1999 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Cypermethrin 257-842-9 52315-07-8 single chemical entity Component is identical to the substance Cypermethrin 257-842-9 52315-07-8 [cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate Cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Swiss 3 No data intraperitoneal 24.0000000000 h yes not applicable Negative no evidence RMS: Belgium Cypermethrin 1999 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Cypermethrin 257-842-9 52315-07-8 single chemical entity Component is identical to the substance Cypermethrin 257-842-9 52315-07-8 [cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate Cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Swiss 3 No data dermal 14.0000000000 D yes not applicable Negative no evidence RMS: Belgium Cypermethrin 1999 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Cypermethrin 257-842-9 52315-07-8 single chemical entity Component is identical to the substance Cypermethrin 257-842-9 52315-07-8 [cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate Cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Swiss 3 No data oral: unspecified 24.0000000000 h yes not applicable Negative no evidence RMS: Belgium Cypermethrin 1999 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Cypermethrin 257-842-9 52315-07-8 single chemical entity Component is identical to the substance Cypermethrin 257-842-9 52315-07-8 [cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate Cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI genome mutation Drosophila SLRL test in vivo According to OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster) No Acceptable Drosophila melanogaster (as animal) Not reported Male oral: feed no data not applicable Positive RMS: Belgium Cypermethrin 1999 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Positive RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Positive RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is part of a group assessment Desmethyl dichlorvos methyl hydrogen phosphate Not in list CH4O4P [O-]P(=O)(O)OC InChI=1/CH5O4P/c1-5-6(2,3)4/h1H3,(H2,2,3,4)/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is part of a group assessment Desmethyl dichlorvos methyl hydrogen phosphate Not in list CH4O4P [O-]P(=O)(O)OC InChI=1/CH5O4P/c1-5-6(2,3)4/h1H3,(H2,2,3,4)/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is part of a group assessment Desmethyl dichlorvos methyl hydrogen phosphate Not in list CH4O4P [O-]P(=O)(O)OC InChI=1/CH5O4P/c1-5-6(2,3)4/h1H3,(H2,2,3,4)/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is part of a group assessment Desmethyl dichlorvos methyl hydrogen phosphate Not in list CH4O4P [O-]P(=O)(O)OC InChI=1/CH5O4P/c1-5-6(2,3)4/h1H3,(H2,2,3,4)/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Positive RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is part of a group assessment Desmethyl dichlorvos methyl hydrogen phosphate Not in list CH4O4P [O-]P(=O)(O)OC InChI=1/CH5O4P/c1-5-6(2,3)4/h1H3,(H2,2,3,4)/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Positive RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is part of a group assessment Desmethyl dichlorvos methyl hydrogen phosphate Not in list CH4O4P [O-]P(=O)(O)OC InChI=1/CH5O4P/c1-5-6(2,3)4/h1H3,(H2,2,3,4)/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is part of a group assessment Desmethyl dichlorvos methyl hydrogen phosphate Not in list CH4O4P [O-]P(=O)(O)OC InChI=1/CH5O4P/c1-5-6(2,3)4/h1H3,(H2,2,3,4)/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is part of a group assessment Desmethyl dichlorvos methyl hydrogen phosphate Not in list CH4O4P [O-]P(=O)(O)OC InChI=1/CH5O4P/c1-5-6(2,3)4/h1H3,(H2,2,3,4)/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is part of a group assessment Desmethyl dichlorvos methyl hydrogen phosphate Not in list CH4O4P [O-]P(=O)(O)OC InChI=1/CH5O4P/c1-5-6(2,3)4/h1H3,(H2,2,3,4)/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is part of a group assessment Desmethyl dichlorvos methyl hydrogen phosphate Not in list CH4O4P [O-]P(=O)(O)OC InChI=1/CH5O4P/c1-5-6(2,3)4/h1H3,(H2,2,3,4)/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Ambiguous no information RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Positive no information RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Positive no information RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro According to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Ambiguous RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro According to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Positive RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Positive RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Positive RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Rat (as animal) Not reported yes, concurrent vehicle without Positive RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) Yes Acceptable Rat (as animal) Not reported yes, concurrent vehicle without Positive RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) CF-1 24 Male/Female inhalation: unspecified 16.0000000000 h no not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) CF-1 24 Male/Female oral: unspecified 16.0000000000 h no not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Hamster (as animal) Chinese 24 Male/Female oral: unspecified 16.0000000000 h no not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Hamster (as animal) Chinese 24 Male/Female inhalation: unspecified 16.0000000000 h no not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Hamster (as animal) Chinese 24 Male/Female oral: unspecified 16.0000000000 h no not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Hamster (as animal) Chinese 24 Male/Female oral: unspecified 16.0000000000 h no not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Hamster (as animal) Chinese 24 Male/Female inhalation: unspecified 16.0000000000 h no not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Hamster (as animal) Chinese 24 Male/Female oral: unspecified 16.0000000000 h no not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) CF-1 24 Male/Female oral: unspecified 16.0000000000 h no not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) CF-1 24 Male/Female inhalation: unspecified 16.0000000000 h no not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Wistar 20 Male oral: gavage yes, concurrent vehicle not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) B6C3F1 10 Male/Female intraperitoneal 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female intraperitoneal 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female intraperitoneal 30.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female intraperitoneal 72.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) 2 Male dermal 72.0000000000 h yes, concurrent vehicle not applicable Positive no evidence RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) 2 Male dermal 1.0000000000 h yes, concurrent vehicle not applicable Positive no evidence RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) 2 Male dermal 48.0000000000 h yes, concurrent vehicle not applicable Positive no evidence RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) 2 Male dermal 24.0000000000 h yes, concurrent vehicle not applicable Positive no evidence RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) 2 Male dermal 6.0000000000 h yes, concurrent vehicle not applicable Positive no evidence RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) 2 Male dermal 12.0000000000 h yes, concurrent vehicle not applicable Positive no evidence RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Fischer344 3 Male oral: gavage 12.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Fischer344 3 Male oral: gavage 2.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable House mouse (as animal) B6C3F1 10 Male/Female oral: gavage 4.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable House mouse (as animal) B6C3F1 10 Male/Female oral: gavage 2.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other gene mutation other in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) CF-1 2 No data oral: unspecified 5.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other gene mutation other in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) NMRI 9 No data subcutaneous 3.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) 2 Male intraperitoneal 4.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) 2 Male intraperitoneal 4.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) 2 Male intraperitoneal 4.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) 2 Male intraperitoneal 4.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other gene mutation other in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) 4 Male intraperitoneal 14.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) 2 Male intraperitoneal 4.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) 2 Male intraperitoneal 4.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) 2 Male intraperitoneal 4.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other gene mutation other in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) 4 Male intraperitoneal 14.0000000000 h yes, concurrent vehicle not applicable Positive RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other chromosome aberration other in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) CD-1 12 Male dermal 24.0000000000 h yes, concurrent vehicle not applicable Positive RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 12 Male dermal 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable Rat (as animal) 20 Male inhalation: unspecified 12.0000000000 h no data not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable Rat (as animal) 20 Male inhalation: unspecified 12.0000000000 h no data not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable Rat (as animal) 20 Male inhalation: unspecified 12.0000000000 h no data not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable Rat (as animal) 20 Male inhalation: unspecified 12.0000000000 h no data not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable Rat (as animal) 20 Male inhalation: unspecified 12.0000000000 h no data not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable Rat (as animal) 20 Male inhalation: unspecified 12.0000000000 h no data not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable Rat (as animal) 20 Male inhalation: unspecified 12.0000000000 h no data not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable Rat (as animal) 20 Male inhalation: unspecified 12.0000000000 h no data not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other chromosome aberration dominant lethal assay in vivo According to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) No Acceptable House mouse (as animal) CD-1 10 Male intraperitoneal yes, concurrent vehicle not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other chromosome aberration dominant lethal assay in vivo According to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) No Acceptable House mouse (as animal) CD-1 Male intraperitoneal yes, concurrent vehicle not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other chromosome aberration mammalian germ cell cytogenetic assay in vivo Equivalent or similar to OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test) Not applicable Acceptable House mouse (as animal) 92 Male intraveneous 96.0000000000 h yes not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other chromosome aberration mammalian germ cell cytogenetic assay in vivo Equivalent or similar to OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test) Not applicable Acceptable House mouse (as animal) 92 Male intraveneous 24.0000000000 h yes not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other chromosome aberration mammalian germ cell cytogenetic assay in vivo Equivalent or similar to OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test) Not applicable Acceptable House mouse (as animal) 92 Male intraveneous 72.0000000000 h yes not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other chromosome aberration mammalian germ cell cytogenetic assay in vivo Equivalent or similar to OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test) Not applicable Acceptable House mouse (as animal) 92 Male intraveneous 48.0000000000 h yes not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other chromosome aberration other in vivo No guideline available Not reported Not applicable Acceptable Drosophila melanogaster (as animal) Not reported Male oral: unspecified no data not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other genome mutation Drosophila SLRL test in vivo Equivalent or similar to OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster) Yes Acceptable Drosophila melanogaster (as animal) Oregon-R Male oral: unspecified no data not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other genome mutation Drosophila SLRL test in vivo Equivalent or similar to OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster) Yes Acceptable Drosophila melanogaster (as animal) Oregon-R Male oral: unspecified yes not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other genome mutation Drosophila SLRL test in vivo Equivalent or similar to OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster) Yes Acceptable Drosophila melanogaster (as animal) Oregon-R Male oral: unspecified yes, concurrent vehicle not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other chromosome aberration other in vivo No guideline available Not reported Not applicable Acceptable Drosophila melanogaster (as animal) Not reported Female oral: unspecified yes not applicable Positive RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other genome mutation other in vivo No guideline available Not reported Not applicable Acceptable Drosophila melanogaster (as animal) Oregon-R 200 Male/Female oral: unspecified yes, concurrent vehicle not applicable Positive RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other gene mutation other in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) CF-1 4 No data inhalation: unspecified 5.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) Yes Acceptable House mouse (as animal) Not reported 12 Female inhalation: unspecified 8.0000000000 week yes not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) Yes Acceptable House mouse (as animal) Not reported 12 Female oral: unspecified yes, concurrent vehicle not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) Yes Acceptable House mouse (as animal) CF-1 Male inhalation: unspecified yes not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) CF-1 24 Male/Female inhalation: unspecified 2.0000000000 h yes, concurrent no treatment not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Hamster (as animal) Chinese 4 Female oral: unspecified 8.0000000000 h yes not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Hamster (as animal) Chinese 8 Male oral: unspecified 24.0000000000 h yes, concurrent no treatment not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Hamster (as animal) Chinese 8 Male inhalation: unspecified 2.0000000000 h yes, concurrent no treatment not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other chromosome aberration mammalian germ cell cytogenetic assay in vivo Equivalent or similar to OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test) Yes Acceptable House mouse (as animal) CF-1 12 Male inhalation: unspecified 2.0000000000 h yes, concurrent no treatment not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other chromosome aberration mammalian germ cell cytogenetic assay in vivo Equivalent or similar to OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test) Yes Acceptable Hamster (as animal) Chinese 8 Male inhalation: unspecified 2.0000000000 h yes, concurrent no treatment not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other chromosome aberration mammalian germ cell cytogenetic assay in vivo Equivalent or similar to OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test) Yes Acceptable Hamster (as animal) Chinese 8 Male oral: unspecified 24.0000000000 h yes, concurrent no treatment not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other chromosome aberration mammalian germ cell cytogenetic assay in vivo Equivalent or similar to OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test) Yes Acceptable House mouse (as animal) CF-1 12 Male inhalation: unspecified 2.0000000000 h yes, concurrent no treatment not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) Yes Acceptable House mouse (as animal) Swiss 8 Male inhalation: unspecified 16.0000000000 h yes not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) Yes Acceptable House mouse (as animal) ICR 12 Male intraperitoneal yes not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) Yes Acceptable House mouse (as animal) ICR 9 Male intraperitoneal yes not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) 92 Male intraperitoneal 36.0000000000 h yes not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) 92 Male intraperitoneal 48.0000000000 h yes not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other chromosome aberration mammalian germ cell cytogenetic assay in vivo Equivalent or similar to OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test) Yes Acceptable House mouse (as animal) 40 Male oral: drinking water yes not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) Yes Acceptable House mouse (as animal) 92 Male intraperitoneal yes not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) 92 Male intraperitoneal 24.0000000000 h yes not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) 92 Male intraperitoneal 72.0000000000 h yes not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) 92 Male intraperitoneal 12.0000000000 h yes not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) 40 Male oral: drinking water yes not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other chromosome aberration mammalian germ cell cytogenetic assay in vivo Equivalent or similar to OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test) Yes Acceptable House mouse (as animal) 8 Male oral: drinking water yes not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) 8 Male oral: drinking water yes not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) Yes Acceptable House mouse (as animal) 20 Male oral: drinking water yes not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) B6C3F1 3 Male intraperitoneal yes not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) B6C3F1 4 Male intraperitoneal yes not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) B6C3F1 4 Male intraperitoneal 17.0000000000 h yes not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) B6C3F1 8 Male intraperitoneal 17.0000000000 h yes not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) B6C3F1 4 Male intraperitoneal yes not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) Not reported 5 Male oral: unspecified 20.0000000000 h yes not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Hamster (as animal) Syrian 6 Female intraperitoneal 24.0000000000 h yes, concurrent no treatment not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Dichlorvos 200-547-7 62-73-7 single chemical entity Component is identical to the substance Dichlorvos 200-547-7 62-73-7 2,2-dichlorovinyl dimethyl phosphate Dichlorvos C4H7Cl2O4P COP(=O)(OC)OC=C(Cl)Cl InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3 organic compound Other Other chromosome aberration mammalian germ cell cytogenetic assay in vivo Equivalent or similar to OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test) Yes Acceptable House mouse (as animal) 20 Male intraperitoneal yes, concurrent no treatment not applicable Negative RMS: Italy Dichlorvos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos 19Jun2006 2006 doi:10.2903/j.efsa.2006.77r
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is identical to the substance Difenoconazole 601-613-1 119446-68-3 1-[[2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl]methyl]-1,2,4-triazole Difenoconazole C19H17Cl2N3O3 CC1COC(O1)(CN2C=NC=N2)C3=C(C=C(C=C3)OC4=CC=C(C=C4)Cl)Cl InChI=1S/C19H17Cl2N3O3/c1-13-9-25-19(27-13,10-24-12-22-11-23-24)17-7-6-16(8-18(17)21)26-15-4-2-14(20)3-5-15/h2-8,11-13H,9-10H2,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes without Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is identical to the substance Difenoconazole 601-613-1 119446-68-3 1-[[2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl]methyl]-1,2,4-triazole Difenoconazole C19H17Cl2N3O3 CC1COC(O1)(CN2C=NC=N2)C3=C(C=C(C=C3)OC4=CC=C(C=C4)Cl)Cl InChI=1S/C19H17Cl2N3O3/c1-13-9-25-19(27-13,10-24-12-22-11-23-24)17-7-6-16(8-18(17)21)26-15-4-2-14(20)3-5-15/h2-8,11-13H,9-10H2,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes with Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is identical to the substance Difenoconazole 601-613-1 119446-68-3 1-[[2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl]methyl]-1,2,4-triazole Difenoconazole C19H17Cl2N3O3 CC1COC(O1)(CN2C=NC=N2)C3=C(C=C(C=C3)OC4=CC=C(C=C4)Cl)Cl InChI=1S/C19H17Cl2N3O3/c1-13-9-25-19(27-13,10-24-12-22-11-23-24)17-7-6-16(8-18(17)21)26-15-4-2-14(20)3-5-15/h2-8,11-13H,9-10H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Negative no information RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is identical to the substance Difenoconazole 601-613-1 119446-68-3 1-[[2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl]methyl]-1,2,4-triazole Difenoconazole C19H17Cl2N3O3 CC1COC(O1)(CN2C=NC=N2)C3=C(C=C(C=C3)OC4=CC=C(C=C4)Cl)Cl InChI=1S/C19H17Cl2N3O3/c1-13-9-25-19(27-13,10-24-12-22-11-23-24)17-7-6-16(8-18(17)21)26-15-4-2-14(20)3-5-15/h2-8,11-13H,9-10H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative no information RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is identical to the substance Difenoconazole 601-613-1 119446-68-3 1-[[2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl]methyl]-1,2,4-triazole Difenoconazole C19H17Cl2N3O3 CC1COC(O1)(CN2C=NC=N2)C3=C(C=C(C=C3)OC4=CC=C(C=C4)Cl)Cl InChI=1S/C19H17Cl2N3O3/c1-13-9-25-19(27-13,10-24-12-22-11-23-24)17-7-6-16(8-18(17)21)26-15-4-2-14(20)3-5-15/h2-8,11-13H,9-10H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is identical to the substance Difenoconazole 601-613-1 119446-68-3 1-[[2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl]methyl]-1,2,4-triazole Difenoconazole C19H17Cl2N3O3 CC1COC(O1)(CN2C=NC=N2)C3=C(C=C(C=C3)OC4=CC=C(C=C4)Cl)Cl InChI=1S/C19H17Cl2N3O3/c1-13-9-25-19(27-13,10-24-12-22-11-23-24)17-7-6-16(8-18(17)21)26-15-4-2-14(20)3-5-15/h2-8,11-13H,9-10H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is identical to the substance Difenoconazole 601-613-1 119446-68-3 1-[[2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl]methyl]-1,2,4-triazole Difenoconazole C19H17Cl2N3O3 CC1COC(O1)(CN2C=NC=N2)C3=C(C=C(C=C3)OC4=CC=C(C=C4)Cl)Cl InChI=1S/C19H17Cl2N3O3/c1-13-9-25-19(27-13,10-24-12-22-11-23-24)17-7-6-16(8-18(17)21)26-15-4-2-14(20)3-5-15/h2-8,11-13H,9-10H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is identical to the substance Difenoconazole 601-613-1 119446-68-3 1-[[2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl]methyl]-1,2,4-triazole Difenoconazole C19H17Cl2N3O3 CC1COC(O1)(CN2C=NC=N2)C3=C(C=C(C=C3)OC4=CC=C(C=C4)Cl)Cl InChI=1S/C19H17Cl2N3O3/c1-13-9-25-19(27-13,10-24-12-22-11-23-24)17-7-6-16(8-18(17)21)26-15-4-2-14(20)3-5-15/h2-8,11-13H,9-10H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is identical to the substance Difenoconazole 601-613-1 119446-68-3 1-[[2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl]methyl]-1,2,4-triazole Difenoconazole C19H17Cl2N3O3 CC1COC(O1)(CN2C=NC=N2)C3=C(C=C(C=C3)OC4=CC=C(C=C4)Cl)Cl InChI=1S/C19H17Cl2N3O3/c1-13-9-25-19(27-13,10-24-12-22-11-23-24)17-7-6-16(8-18(17)21)26-15-4-2-14(20)3-5-15/h2-8,11-13H,9-10H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is identical to the substance Difenoconazole 601-613-1 119446-68-3 1-[[2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl]methyl]-1,2,4-triazole Difenoconazole C19H17Cl2N3O3 CC1COC(O1)(CN2C=NC=N2)C3=C(C=C(C=C3)OC4=CC=C(C=C4)Cl)Cl InChI=1S/C19H17Cl2N3O3/c1-13-9-25-19(27-13,10-24-12-22-11-23-24)17-7-6-16(8-18(17)21)26-15-4-2-14(20)3-5-15/h2-8,11-13H,9-10H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is identical to the substance Difenoconazole 601-613-1 119446-68-3 1-[[2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl]methyl]-1,2,4-triazole Difenoconazole C19H17Cl2N3O3 CC1COC(O1)(CN2C=NC=N2)C3=C(C=C(C=C3)OC4=CC=C(C=C4)Cl)Cl InChI=1S/C19H17Cl2N3O3/c1-13-9-25-19(27-13,10-24-12-22-11-23-24)17-7-6-16(8-18(17)21)26-15-4-2-14(20)3-5-15/h2-8,11-13H,9-10H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is identical to the substance Difenoconazole 601-613-1 119446-68-3 1-[[2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl]methyl]-1,2,4-triazole Difenoconazole C19H17Cl2N3O3 CC1COC(O1)(CN2C=NC=N2)C3=C(C=C(C=C3)OC4=CC=C(C=C4)Cl)Cl InChI=1S/C19H17Cl2N3O3/c1-13-9-25-19(27-13,10-24-12-22-11-23-24)17-7-6-16(8-18(17)21)26-15-4-2-14(20)3-5-15/h2-8,11-13H,9-10H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is identical to the substance Difenoconazole 601-613-1 119446-68-3 1-[[2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl]methyl]-1,2,4-triazole Difenoconazole C19H17Cl2N3O3 CC1COC(O1)(CN2C=NC=N2)C3=C(C=C(C=C3)OC4=CC=C(C=C4)Cl)Cl InChI=1S/C19H17Cl2N3O3/c1-13-9-25-19(27-13,10-24-12-22-11-23-24)17-7-6-16(8-18(17)21)26-15-4-2-14(20)3-5-15/h2-8,11-13H,9-10H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is identical to the substance Difenoconazole 601-613-1 119446-68-3 1-[[2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl]methyl]-1,2,4-triazole Difenoconazole C19H17Cl2N3O3 CC1COC(O1)(CN2C=NC=N2)C3=C(C=C(C=C3)OC4=CC=C(C=C4)Cl)Cl InChI=1S/C19H17Cl2N3O3/c1-13-9-25-19(27-13,10-24-12-22-11-23-24)17-7-6-16(8-18(17)21)26-15-4-2-14(20)3-5-15/h2-8,11-13H,9-10H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is identical to the substance Difenoconazole 601-613-1 119446-68-3 1-[[2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl]methyl]-1,2,4-triazole Difenoconazole C19H17Cl2N3O3 CC1COC(O1)(CN2C=NC=N2)C3=C(C=C(C=C3)OC4=CC=C(C=C4)Cl)Cl InChI=1S/C19H17Cl2N3O3/c1-13-9-25-19(27-13,10-24-12-22-11-23-24)17-7-6-16(8-18(17)21)26-15-4-2-14(20)3-5-15/h2-8,11-13H,9-10H2,1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes without Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is identical to the substance Difenoconazole 601-613-1 119446-68-3 1-[[2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl]methyl]-1,2,4-triazole Difenoconazole C19H17Cl2N3O3 CC1COC(O1)(CN2C=NC=N2)C3=C(C=C(C=C3)OC4=CC=C(C=C4)Cl)Cl InChI=1S/C19H17Cl2N3O3/c1-13-9-25-19(27-13,10-24-12-22-11-23-24)17-7-6-16(8-18(17)21)26-15-4-2-14(20)3-5-15/h2-8,11-13H,9-10H2,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Ambiguous RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is identical to the substance Difenoconazole 601-613-1 119446-68-3 1-[[2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl]methyl]-1,2,4-triazole Difenoconazole C19H17Cl2N3O3 CC1COC(O1)(CN2C=NC=N2)C3=C(C=C(C=C3)OC4=CC=C(C=C4)Cl)Cl InChI=1S/C19H17Cl2N3O3/c1-13-9-25-19(27-13,10-24-12-22-11-23-24)17-7-6-16(8-18(17)21)26-15-4-2-14(20)3-5-15/h2-8,11-13H,9-10H2,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Ambiguous RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is identical to the substance Difenoconazole 601-613-1 119446-68-3 1-[[2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl]methyl]-1,2,4-triazole Difenoconazole C19H17Cl2N3O3 CC1COC(O1)(CN2C=NC=N2)C3=C(C=C(C=C3)OC4=CC=C(C=C4)Cl)Cl InChI=1S/C19H17Cl2N3O3/c1-13-9-25-19(27-13,10-24-12-22-11-23-24)17-7-6-16(8-18(17)21)26-15-4-2-14(20)3-5-15/h2-8,11-13H,9-10H2,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is identical to the substance Difenoconazole 601-613-1 119446-68-3 1-[[2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl]methyl]-1,2,4-triazole Difenoconazole C19H17Cl2N3O3 CC1COC(O1)(CN2C=NC=N2)C3=C(C=C(C=C3)OC4=CC=C(C=C4)Cl)Cl InChI=1S/C19H17Cl2N3O3/c1-13-9-25-19(27-13,10-24-12-22-11-23-24)17-7-6-16(8-18(17)21)26-15-4-2-14(20)3-5-15/h2-8,11-13H,9-10H2,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is identical to the substance Difenoconazole 601-613-1 119446-68-3 1-[[2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl]methyl]-1,2,4-triazole Difenoconazole C19H17Cl2N3O3 CC1COC(O1)(CN2C=NC=N2)C3=C(C=C(C=C3)OC4=CC=C(C=C4)Cl)Cl InChI=1S/C19H17Cl2N3O3/c1-13-9-25-19(27-13,10-24-12-22-11-23-24)17-7-6-16(8-18(17)21)26-15-4-2-14(20)3-5-15/h2-8,11-13H,9-10H2,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Ambiguous RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is identical to the substance Difenoconazole 601-613-1 119446-68-3 1-[[2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl]methyl]-1,2,4-triazole Difenoconazole C19H17Cl2N3O3 CC1COC(O1)(CN2C=NC=N2)C3=C(C=C(C=C3)OC4=CC=C(C=C4)Cl)Cl InChI=1S/C19H17Cl2N3O3/c1-13-9-25-19(27-13,10-24-12-22-11-23-24)17-7-6-16(8-18(17)21)26-15-4-2-14(20)3-5-15/h2-8,11-13H,9-10H2,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is identical to the substance Difenoconazole 601-613-1 119446-68-3 1-[[2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl]methyl]-1,2,4-triazole Difenoconazole C19H17Cl2N3O3 CC1COC(O1)(CN2C=NC=N2)C3=C(C=C(C=C3)OC4=CC=C(C=C4)Cl)Cl InChI=1S/C19H17Cl2N3O3/c1-13-9-25-19(27-13,10-24-12-22-11-23-24)17-7-6-16(8-18(17)21)26-15-4-2-14(20)3-5-15/h2-8,11-13H,9-10H2,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Tif:MAGf(SPF) 16 Male/Female oral: unspecified 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is identical to the substance Difenoconazole 601-613-1 119446-68-3 1-[[2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl]methyl]-1,2,4-triazole Difenoconazole C19H17Cl2N3O3 CC1COC(O1)(CN2C=NC=N2)C3=C(C=C(C=C3)OC4=CC=C(C=C4)Cl)Cl InChI=1S/C19H17Cl2N3O3/c1-13-9-25-19(27-13,10-24-12-22-11-23-24)17-7-6-16(8-18(17)21)26-15-4-2-14(20)3-5-15/h2-8,11-13H,9-10H2,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Tif:MAGf(SPF) 16 Male/Female oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is identical to the substance Difenoconazole 601-613-1 119446-68-3 1-[[2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl]methyl]-1,2,4-triazole Difenoconazole C19H17Cl2N3O3 CC1COC(O1)(CN2C=NC=N2)C3=C(C=C(C=C3)OC4=CC=C(C=C4)Cl)Cl InChI=1S/C19H17Cl2N3O3/c1-13-9-25-19(27-13,10-24-12-22-11-23-24)17-7-6-16(8-18(17)21)26-15-4-2-14(20)3-5-15/h2-8,11-13H,9-10H2,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Tif:MAGf(SPF) 16 Male/Female oral: unspecified 16.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Difenoconazole-benzoic acid 2-chloro-4-(4-chlorophenoxy)benzoic acid Difenoconazole-benzoic acid C13H8Cl2O3 OC(=O)c1ccc(cc1Cl)Oc2ccc(Cl)cc2 InChI=1S/C13H8Cl2O3/c14-8-1-3-9(4-2-8)18-10-5-6-11(13(16)17)12(15)7-10/h1-7H,(H,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Difenoconazole-benzoic acid 2-chloro-4-(4-chlorophenoxy)benzoic acid Difenoconazole-benzoic acid C13H8Cl2O3 OC(=O)c1ccc(cc1Cl)Oc2ccc(Cl)cc2 InChI=1S/C13H8Cl2O3/c14-8-1-3-9(4-2-8)18-10-5-6-11(13(16)17)12(15)7-10/h1-7H,(H,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Difenoconazole-benzoic acid 2-chloro-4-(4-chlorophenoxy)benzoic acid Difenoconazole-benzoic acid C13H8Cl2O3 OC(=O)c1ccc(cc1Cl)Oc2ccc(Cl)cc2 InChI=1S/C13H8Cl2O3/c14-8-1-3-9(4-2-8)18-10-5-6-11(13(16)17)12(15)7-10/h1-7H,(H,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Difenoconazole-benzoic acid 2-chloro-4-(4-chlorophenoxy)benzoic acid Difenoconazole-benzoic acid C13H8Cl2O3 OC(=O)c1ccc(cc1Cl)Oc2ccc(Cl)cc2 InChI=1S/C13H8Cl2O3/c14-8-1-3-9(4-2-8)18-10-5-6-11(13(16)17)12(15)7-10/h1-7H,(H,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Difenoconazole-benzoic acid 2-chloro-4-(4-chlorophenoxy)benzoic acid Difenoconazole-benzoic acid C13H8Cl2O3 OC(=O)c1ccc(cc1Cl)Oc2ccc(Cl)cc2 InChI=1S/C13H8Cl2O3/c14-8-1-3-9(4-2-8)18-10-5-6-11(13(16)17)12(15)7-10/h1-7H,(H,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Difenoconazole-benzoic acid 2-chloro-4-(4-chlorophenoxy)benzoic acid Difenoconazole-benzoic acid C13H8Cl2O3 OC(=O)c1ccc(cc1Cl)Oc2ccc(Cl)cc2 InChI=1S/C13H8Cl2O3/c14-8-1-3-9(4-2-8)18-10-5-6-11(13(16)17)12(15)7-10/h1-7H,(H,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Difenoconazole-benzoic acid 2-chloro-4-(4-chlorophenoxy)benzoic acid Difenoconazole-benzoic acid C13H8Cl2O3 OC(=O)c1ccc(cc1Cl)Oc2ccc(Cl)cc2 InChI=1S/C13H8Cl2O3/c14-8-1-3-9(4-2-8)18-10-5-6-11(13(16)17)12(15)7-10/h1-7H,(H,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Difenoconazole-benzoic acid 2-chloro-4-(4-chlorophenoxy)benzoic acid Difenoconazole-benzoic acid C13H8Cl2O3 OC(=O)c1ccc(cc1Cl)Oc2ccc(Cl)cc2 InChI=1S/C13H8Cl2O3/c14-8-1-3-9(4-2-8)18-10-5-6-11(13(16)17)12(15)7-10/h1-7H,(H,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Difenoconazole-benzoic acid 2-chloro-4-(4-chlorophenoxy)benzoic acid Difenoconazole-benzoic acid C13H8Cl2O3 OC(=O)c1ccc(cc1Cl)Oc2ccc(Cl)cc2 InChI=1S/C13H8Cl2O3/c14-8-1-3-9(4-2-8)18-10-5-6-11(13(16)17)12(15)7-10/h1-7H,(H,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Difenoconazole-benzoic acid 2-chloro-4-(4-chlorophenoxy)benzoic acid Difenoconazole-benzoic acid C13H8Cl2O3 OC(=O)c1ccc(cc1Cl)Oc2ccc(Cl)cc2 InChI=1S/C13H8Cl2O3/c14-8-1-3-9(4-2-8)18-10-5-6-11(13(16)17)12(15)7-10/h1-7H,(H,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes with Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes with Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes without Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes without Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes without Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes with Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes with Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes without Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes without Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes without Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes with Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes with Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes without Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes with Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes without Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes with Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes with Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes without Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Difenoconazole-ketone 1-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-(1H-1,2,4-triazol-1-yl)ethanone Not in list C16H11Cl2N3O2 O=C(Cn1cncn1)c3ccc(Oc2ccc(Cl)cc2)cc3Cl InChI=1S/C16H11Cl2N3O2/c17-11-1-3-12(4-2-11)23-13-5-6-14(15(18)7-13)16(22)8-21-10-19-9-20-21/h1-7,9-10H,8H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Difenoconazole-ketone 1-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-(1H-1,2,4-triazol-1-yl)ethanone Not in list C16H11Cl2N3O2 O=C(Cn1cncn1)c3ccc(Oc2ccc(Cl)cc2)cc3Cl InChI=1S/C16H11Cl2N3O2/c17-11-1-3-12(4-2-11)23-13-5-6-14(15(18)7-13)16(22)8-21-10-19-9-20-21/h1-7,9-10H,8H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Difenoconazole-ketone 1-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-(1H-1,2,4-triazol-1-yl)ethanone Not in list C16H11Cl2N3O2 O=C(Cn1cncn1)c3ccc(Oc2ccc(Cl)cc2)cc3Cl InChI=1S/C16H11Cl2N3O2/c17-11-1-3-12(4-2-11)23-13-5-6-14(15(18)7-13)16(22)8-21-10-19-9-20-21/h1-7,9-10H,8H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Difenoconazole-ketone 1-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-(1H-1,2,4-triazol-1-yl)ethanone Not in list C16H11Cl2N3O2 O=C(Cn1cncn1)c3ccc(Oc2ccc(Cl)cc2)cc3Cl InChI=1S/C16H11Cl2N3O2/c17-11-1-3-12(4-2-11)23-13-5-6-14(15(18)7-13)16(22)8-21-10-19-9-20-21/h1-7,9-10H,8H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Difenoconazole-ketone 1-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-(1H-1,2,4-triazol-1-yl)ethanone Not in list C16H11Cl2N3O2 O=C(Cn1cncn1)c3ccc(Oc2ccc(Cl)cc2)cc3Cl InChI=1S/C16H11Cl2N3O2/c17-11-1-3-12(4-2-11)23-13-5-6-14(15(18)7-13)16(22)8-21-10-19-9-20-21/h1-7,9-10H,8H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Difenoconazole-ketone 1-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-(1H-1,2,4-triazol-1-yl)ethanone Not in list C16H11Cl2N3O2 O=C(Cn1cncn1)c3ccc(Oc2ccc(Cl)cc2)cc3Cl InChI=1S/C16H11Cl2N3O2/c17-11-1-3-12(4-2-11)23-13-5-6-14(15(18)7-13)16(22)8-21-10-19-9-20-21/h1-7,9-10H,8H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Difenoconazole-ketone 1-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-(1H-1,2,4-triazol-1-yl)ethanone Not in list C16H11Cl2N3O2 O=C(Cn1cncn1)c3ccc(Oc2ccc(Cl)cc2)cc3Cl InChI=1S/C16H11Cl2N3O2/c17-11-1-3-12(4-2-11)23-13-5-6-14(15(18)7-13)16(22)8-21-10-19-9-20-21/h1-7,9-10H,8H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Difenoconazole-ketone 1-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-(1H-1,2,4-triazol-1-yl)ethanone Not in list C16H11Cl2N3O2 O=C(Cn1cncn1)c3ccc(Oc2ccc(Cl)cc2)cc3Cl InChI=1S/C16H11Cl2N3O2/c17-11-1-3-12(4-2-11)23-13-5-6-14(15(18)7-13)16(22)8-21-10-19-9-20-21/h1-7,9-10H,8H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Difenoconazole-ketone 1-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-(1H-1,2,4-triazol-1-yl)ethanone Not in list C16H11Cl2N3O2 O=C(Cn1cncn1)c3ccc(Oc2ccc(Cl)cc2)cc3Cl InChI=1S/C16H11Cl2N3O2/c17-11-1-3-12(4-2-11)23-13-5-6-14(15(18)7-13)16(22)8-21-10-19-9-20-21/h1-7,9-10H,8H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Difenoconazole-ketone 1-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-(1H-1,2,4-triazol-1-yl)ethanone Not in list C16H11Cl2N3O2 O=C(Cn1cncn1)c3ccc(Oc2ccc(Cl)cc2)cc3Cl InChI=1S/C16H11Cl2N3O2/c17-11-1-3-12(4-2-11)23-13-5-6-14(15(18)7-13)16(22)8-21-10-19-9-20-21/h1-7,9-10H,8H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Difenoconazole-alcohol 1-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-(1H-1,2,4-triazol-1-yl)ethanol Not in list C16H13Cl2N3O2 OC(Cn1cncn1)c3ccc(Oc2ccc(Cl)cc2)cc3Cl InChI=1S/C16H13Cl2N3O2/c17-11-1-3-12(4-2-11)23-13-5-6-14(15(18)7-13)16(22)8-21-10-19-9-20-21/h1-7,9-10,16,22H,8H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Difenoconazole-alcohol 1-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-(1H-1,2,4-triazol-1-yl)ethanol Not in list C16H13Cl2N3O2 OC(Cn1cncn1)c3ccc(Oc2ccc(Cl)cc2)cc3Cl InChI=1S/C16H13Cl2N3O2/c17-11-1-3-12(4-2-11)23-13-5-6-14(15(18)7-13)16(22)8-21-10-19-9-20-21/h1-7,9-10,16,22H,8H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Difenoconazole-alcohol 1-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-(1H-1,2,4-triazol-1-yl)ethanol Not in list C16H13Cl2N3O2 OC(Cn1cncn1)c3ccc(Oc2ccc(Cl)cc2)cc3Cl InChI=1S/C16H13Cl2N3O2/c17-11-1-3-12(4-2-11)23-13-5-6-14(15(18)7-13)16(22)8-21-10-19-9-20-21/h1-7,9-10,16,22H,8H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Difenoconazole-alcohol 1-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-(1H-1,2,4-triazol-1-yl)ethanol Not in list C16H13Cl2N3O2 OC(Cn1cncn1)c3ccc(Oc2ccc(Cl)cc2)cc3Cl InChI=1S/C16H13Cl2N3O2/c17-11-1-3-12(4-2-11)23-13-5-6-14(15(18)7-13)16(22)8-21-10-19-9-20-21/h1-7,9-10,16,22H,8H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Difenoconazole-alcohol 1-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-(1H-1,2,4-triazol-1-yl)ethanol Not in list C16H13Cl2N3O2 OC(Cn1cncn1)c3ccc(Oc2ccc(Cl)cc2)cc3Cl InChI=1S/C16H13Cl2N3O2/c17-11-1-3-12(4-2-11)23-13-5-6-14(15(18)7-13)16(22)8-21-10-19-9-20-21/h1-7,9-10,16,22H,8H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Difenoconazole-alcohol 1-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-(1H-1,2,4-triazol-1-yl)ethanol Not in list C16H13Cl2N3O2 OC(Cn1cncn1)c3ccc(Oc2ccc(Cl)cc2)cc3Cl InChI=1S/C16H13Cl2N3O2/c17-11-1-3-12(4-2-11)23-13-5-6-14(15(18)7-13)16(22)8-21-10-19-9-20-21/h1-7,9-10,16,22H,8H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Difenoconazole-alcohol 1-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-(1H-1,2,4-triazol-1-yl)ethanol Not in list C16H13Cl2N3O2 OC(Cn1cncn1)c3ccc(Oc2ccc(Cl)cc2)cc3Cl InChI=1S/C16H13Cl2N3O2/c17-11-1-3-12(4-2-11)23-13-5-6-14(15(18)7-13)16(22)8-21-10-19-9-20-21/h1-7,9-10,16,22H,8H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Difenoconazole-alcohol 1-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-(1H-1,2,4-triazol-1-yl)ethanol Not in list C16H13Cl2N3O2 OC(Cn1cncn1)c3ccc(Oc2ccc(Cl)cc2)cc3Cl InChI=1S/C16H13Cl2N3O2/c17-11-1-3-12(4-2-11)23-13-5-6-14(15(18)7-13)16(22)8-21-10-19-9-20-21/h1-7,9-10,16,22H,8H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Difenoconazole-alcohol 1-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-(1H-1,2,4-triazol-1-yl)ethanol Not in list C16H13Cl2N3O2 OC(Cn1cncn1)c3ccc(Oc2ccc(Cl)cc2)cc3Cl InChI=1S/C16H13Cl2N3O2/c17-11-1-3-12(4-2-11)23-13-5-6-14(15(18)7-13)16(22)8-21-10-19-9-20-21/h1-7,9-10,16,22H,8H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Difenoconazole-alcohol 1-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-(1H-1,2,4-triazol-1-yl)ethanol Not in list C16H13Cl2N3O2 OC(Cn1cncn1)c3ccc(Oc2ccc(Cl)cc2)cc3Cl InChI=1S/C16H13Cl2N3O2/c17-11-1-3-12(4-2-11)23-13-5-6-14(15(18)7-13)16(22)8-21-10-19-9-20-21/h1-7,9-10,16,22H,8H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is identical to the substance Dimethoate 200-480-3 60-51-5 O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate Dimethoate C5H12NO3PS2 CNC(=O)CSP(=S)(OC)OC InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is identical to the substance Dimethoate 200-480-3 60-51-5 O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate Dimethoate C5H12NO3PS2 CNC(=O)CSP(=S)(OC)OC InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is identical to the substance Dimethoate 200-480-3 60-51-5 O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate Dimethoate C5H12NO3PS2 CNC(=O)CSP(=S)(OC)OC InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Positive RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is identical to the substance Dimethoate 200-480-3 60-51-5 O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate Dimethoate C5H12NO3PS2 CNC(=O)CSP(=S)(OC)OC InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is identical to the substance Dimethoate 200-480-3 60-51-5 O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate Dimethoate C5H12NO3PS2 CNC(=O)CSP(=S)(OC)OC InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is identical to the substance Dimethoate 200-480-3 60-51-5 O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate Dimethoate C5H12NO3PS2 CNC(=O)CSP(=S)(OC)OC InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Positive RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is identical to the substance Dimethoate 200-480-3 60-51-5 O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate Dimethoate C5H12NO3PS2 CNC(=O)CSP(=S)(OC)OC InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is identical to the substance Dimethoate 200-480-3 60-51-5 O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate Dimethoate C5H12NO3PS2 CNC(=O)CSP(=S)(OC)OC InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is identical to the substance Dimethoate 200-480-3 60-51-5 O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate Dimethoate C5H12NO3PS2 CNC(=O)CSP(=S)(OC)OC InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Positive RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is identical to the substance Dimethoate 200-480-3 60-51-5 O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate Dimethoate C5H12NO3PS2 CNC(=O)CSP(=S)(OC)OC InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Positive RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is identical to the substance Dimethoate 200-480-3 60-51-5 O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate Dimethoate C5H12NO3PS2 CNC(=O)CSP(=S)(OC)OC InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is identical to the substance Dimethoate 200-480-3 60-51-5 O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate Dimethoate C5H12NO3PS2 CNC(=O)CSP(=S)(OC)OC InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is identical to the substance Dimethoate 200-480-3 60-51-5 O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate Dimethoate C5H12NO3PS2 CNC(=O)CSP(=S)(OC)OC InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is identical to the substance Dimethoate 200-480-3 60-51-5 O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate Dimethoate C5H12NO3PS2 CNC(=O)CSP(=S)(OC)OC InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Positive RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is identical to the substance Dimethoate 200-480-3 60-51-5 O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate Dimethoate C5H12NO3PS2 CNC(=O)CSP(=S)(OC)OC InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Positive RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is identical to the substance Dimethoate 200-480-3 60-51-5 O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate Dimethoate C5H12NO3PS2 CNC(=O)CSP(=S)(OC)OC InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is identical to the substance Dimethoate 200-480-3 60-51-5 O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate Dimethoate C5H12NO3PS2 CNC(=O)CSP(=S)(OC)OC InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is identical to the substance Dimethoate 200-480-3 60-51-5 O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate Dimethoate C5H12NO3PS2 CNC(=O)CSP(=S)(OC)OC InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is identical to the substance Dimethoate 200-480-3 60-51-5 O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate Dimethoate C5H12NO3PS2 CNC(=O)CSP(=S)(OC)OC InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Inconclusive RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is identical to the substance Dimethoate 200-480-3 60-51-5 O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate Dimethoate C5H12NO3PS2 CNC(=O)CSP(=S)(OC)OC InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Inconclusive RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is identical to the substance Dimethoate 200-480-3 60-51-5 O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate Dimethoate C5H12NO3PS2 CNC(=O)CSP(=S)(OC)OC InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7) organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes without Positive RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is identical to the substance Dimethoate 200-480-3 60-51-5 O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate Dimethoate C5H12NO3PS2 CNC(=O)CSP(=S)(OC)OC InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female intraperitoneal 72.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity$indirect evidence-systemic toxicity RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is identical to the substance Dimethoate 200-480-3 60-51-5 O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate Dimethoate C5H12NO3PS2 CNC(=O)CSP(=S)(OC)OC InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female intraperitoneal 30.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity$indirect evidence-systemic toxicity RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is identical to the substance Dimethoate 200-480-3 60-51-5 O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate Dimethoate C5H12NO3PS2 CNC(=O)CSP(=S)(OC)OC InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female intraperitoneal 6.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity$indirect evidence-systemic toxicity RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is identical to the substance Dimethoate 200-480-3 60-51-5 O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate Dimethoate C5H12NO3PS2 CNC(=O)CSP(=S)(OC)OC InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female intraperitoneal 48.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity$indirect evidence-systemic toxicity RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is identical to the substance Dimethoate 200-480-3 60-51-5 O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate Dimethoate C5H12NO3PS2 CNC(=O)CSP(=S)(OC)OC InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable House mouse (as animal) Not reported 6 No data oral: gavage 6.0000000000 h yes, concurrent vehicle not applicable Inconclusive no evidence RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is identical to the substance Dimethoate 200-480-3 60-51-5 O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate Dimethoate C5H12NO3PS2 CNC(=O)CSP(=S)(OC)OC InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7) organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Sprague-Dawley 10 Male/Female intraperitoneal 6.0000000000 h yes not applicable Negative RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is identical to the substance Dimethoate 200-480-3 60-51-5 O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate Dimethoate C5H12NO3PS2 CNC(=O)CSP(=S)(OC)OC InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7) organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Sprague-Dawley 10 Male/Female intraperitoneal 16.0000000000 h yes not applicable Negative RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is identical to the substance Dimethoate 200-480-3 60-51-5 O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate Dimethoate C5H12NO3PS2 CNC(=O)CSP(=S)(OC)OC InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7) organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Sprague-Dawley 10 Male/Female intraperitoneal 24.0000000000 h yes not applicable Negative RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is a metabolite of the substance O-desmethyldimethoate S-methyl S-[2-(methylamino)-2-oxoethyl] hydrogen phosphorodithioate Not in list C4H10NO3PS2 O=P(O)(SC)SCC(=O)NC InChI=1/C4H10NO3PS2/c1-5-4(6)3-11-9(7,8)10-2/h3H2,1-2H3,(H,5,6)(H,7,8) organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable House mouse (as animal) CFLP 10 Male intraperitoneal 48.0000000000 h yes not applicable Positive RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is identical to the substance Dimethoate 200-480-3 60-51-5 O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate Dimethoate C5H12NO3PS2 CNC(=O)CSP(=S)(OC)OC InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7) organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable House mouse (as animal) CFLP 10 Male intraperitoneal 48.0000000000 h yes not applicable Ambiguous RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is identical to the substance Dimethoate 200-480-3 60-51-5 O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate Dimethoate C5H12NO3PS2 CNC(=O)CSP(=S)(OC)OC InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7) organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable House mouse (as animal) CFLP 10 Male intraperitoneal 24.0000000000 h yes not applicable Ambiguous RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is a metabolite of the substance O-desmethyldimethoate S-methyl S-[2-(methylamino)-2-oxoethyl] hydrogen phosphorodithioate Not in list C4H10NO3PS2 O=P(O)(SC)SCC(=O)NC InChI=1/C4H10NO3PS2/c1-5-4(6)3-11-9(7,8)10-2/h3H2,1-2H3,(H,5,6)(H,7,8) organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable House mouse (as animal) CFLP 10 Male intraperitoneal 24.0000000000 h yes not applicable Positive RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is identical to the substance Dimethoate 200-480-3 60-51-5 O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate Dimethoate C5H12NO3PS2 CNC(=O)CSP(=S)(OC)OC InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7) organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Wistar 10 Male oral: gavage 24.0000000000 h yes not applicable Ambiguous RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is identical to the substance Dimethoate 200-480-3 60-51-5 O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate Dimethoate C5H12NO3PS2 CNC(=O)CSP(=S)(OC)OC InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7) organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Wistar 10 Male oral: gavage 24.0000000000 h yes not applicable Ambiguous RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is identical to the substance Dimethoate 200-480-3 60-51-5 O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate Dimethoate C5H12NO3PS2 CNC(=O)CSP(=S)(OC)OC InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7) organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Wistar 10 Male oral: gavage yes not applicable Ambiguous RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is identical to the substance Dimethoate 200-480-3 60-51-5 O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate Dimethoate C5H12NO3PS2 CNC(=O)CSP(=S)(OC)OC InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7) organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No data Acceptable House mouse (as animal) Not reported No data Not reported 48.0000000000 h no not applicable Inconclusive RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is identical to the substance Dimethoate 200-480-3 60-51-5 O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate Dimethoate C5H12NO3PS2 CNC(=O)CSP(=S)(OC)OC InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7) organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No data Acceptable House mouse (as animal) Not reported No data Not reported 72.0000000000 h no not applicable Inconclusive RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is identical to the substance Dimethoate 200-480-3 60-51-5 O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate Dimethoate C5H12NO3PS2 CNC(=O)CSP(=S)(OC)OC InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7) organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No data Acceptable House mouse (as animal) Not reported No data Not reported 24.0000000000 h no not applicable Inconclusive RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is identical to the substance Dimethoate 200-480-3 60-51-5 O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate Dimethoate C5H12NO3PS2 CNC(=O)CSP(=S)(OC)OC InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7) organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Hamster (as animal) Syrian 4 Female intraperitoneal 24.0000000000 h yes not applicable Ambiguous RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is identical to the substance Dimethoate 200-480-3 60-51-5 O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate Dimethoate C5H12NO3PS2 CNC(=O)CSP(=S)(OC)OC InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7) organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo Equivalent or similar to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) Yes Acceptable Rat (as animal) Wistar Male oral: gavage 4.0000000000 h no not applicable Negative RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is identical to the substance Dimethoate 200-480-3 60-51-5 O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate Dimethoate C5H12NO3PS2 CNC(=O)CSP(=S)(OC)OC InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7) organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo Equivalent or similar to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) Yes Acceptable Rat (as animal) Wistar Male oral: gavage 12.0000000000 h no not applicable Negative RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is identical to the substance Dimethoate 200-480-3 60-51-5 O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate Dimethoate C5H12NO3PS2 CNC(=O)CSP(=S)(OC)OC InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7) organic compound Other Other chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) Yes Acceptable House mouse (as animal) NMRI 25 Male oral: drinking water yes not applicable Negative RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is a metabolite of the substance Omethoate 214-197-8 1113-02-6 2-Dimethoxyphosphorylsulfanyl-N-methylacetamide Omethoate C5H12NO4PS CNC(=O)CSP(=O)(OC)OC InChI=1S/C5H12NO4PS/c1-6-5(7)4-12-11(8,9-2)10-3/h4H2,1-3H3,(H,6,7) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is a metabolite of the substance Omethoate 214-197-8 1113-02-6 2-Dimethoxyphosphorylsulfanyl-N-methylacetamide Omethoate C5H12NO4PS CNC(=O)CSP(=O)(OC)OC InChI=1S/C5H12NO4PS/c1-6-5(7)4-12-11(8,9-2)10-3/h4H2,1-3H3,(H,6,7) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is a metabolite of the substance Omethoate 214-197-8 1113-02-6 2-Dimethoxyphosphorylsulfanyl-N-methylacetamide Omethoate C5H12NO4PS CNC(=O)CSP(=O)(OC)OC InChI=1S/C5H12NO4PS/c1-6-5(7)4-12-11(8,9-2)10-3/h4H2,1-3H3,(H,6,7) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is a metabolite of the substance Omethoate 214-197-8 1113-02-6 2-Dimethoxyphosphorylsulfanyl-N-methylacetamide Omethoate C5H12NO4PS CNC(=O)CSP(=O)(OC)OC InChI=1S/C5H12NO4PS/c1-6-5(7)4-12-11(8,9-2)10-3/h4H2,1-3H3,(H,6,7) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Positive RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is a metabolite of the substance Omethoate 214-197-8 1113-02-6 2-Dimethoxyphosphorylsulfanyl-N-methylacetamide Omethoate C5H12NO4PS CNC(=O)CSP(=O)(OC)OC InChI=1S/C5H12NO4PS/c1-6-5(7)4-12-11(8,9-2)10-3/h4H2,1-3H3,(H,6,7) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is a metabolite of the substance Omethoate 214-197-8 1113-02-6 2-Dimethoxyphosphorylsulfanyl-N-methylacetamide Omethoate C5H12NO4PS CNC(=O)CSP(=O)(OC)OC InChI=1S/C5H12NO4PS/c1-6-5(7)4-12-11(8,9-2)10-3/h4H2,1-3H3,(H,6,7) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Positive RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is a metabolite of the substance Omethoate 214-197-8 1113-02-6 2-Dimethoxyphosphorylsulfanyl-N-methylacetamide Omethoate C5H12NO4PS CNC(=O)CSP(=O)(OC)OC InChI=1S/C5H12NO4PS/c1-6-5(7)4-12-11(8,9-2)10-3/h4H2,1-3H3,(H,6,7) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Positive RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is a metabolite of the substance Omethoate 214-197-8 1113-02-6 2-Dimethoxyphosphorylsulfanyl-N-methylacetamide Omethoate C5H12NO4PS CNC(=O)CSP(=O)(OC)OC InChI=1S/C5H12NO4PS/c1-6-5(7)4-12-11(8,9-2)10-3/h4H2,1-3H3,(H,6,7) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Positive RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is a metabolite of the substance Omethoate 214-197-8 1113-02-6 2-Dimethoxyphosphorylsulfanyl-N-methylacetamide Omethoate C5H12NO4PS CNC(=O)CSP(=O)(OC)OC InChI=1S/C5H12NO4PS/c1-6-5(7)4-12-11(8,9-2)10-3/h4H2,1-3H3,(H,6,7) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is a metabolite of the substance Omethoate 214-197-8 1113-02-6 2-Dimethoxyphosphorylsulfanyl-N-methylacetamide Omethoate C5H12NO4PS CNC(=O)CSP(=O)(OC)OC InChI=1S/C5H12NO4PS/c1-6-5(7)4-12-11(8,9-2)10-3/h4H2,1-3H3,(H,6,7) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is a metabolite of the substance Omethoate 214-197-8 1113-02-6 2-Dimethoxyphosphorylsulfanyl-N-methylacetamide Omethoate C5H12NO4PS CNC(=O)CSP(=O)(OC)OC InChI=1S/C5H12NO4PS/c1-6-5(7)4-12-11(8,9-2)10-3/h4H2,1-3H3,(H,6,7) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes without Positive RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is a metabolite of the substance Omethoate 214-197-8 1113-02-6 2-Dimethoxyphosphorylsulfanyl-N-methylacetamide Omethoate C5H12NO4PS CNC(=O)CSP(=O)(OC)OC InChI=1S/C5H12NO4PS/c1-6-5(7)4-12-11(8,9-2)10-3/h4H2,1-3H3,(H,6,7) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes with Positive RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is a metabolite of the substance Omethoate 214-197-8 1113-02-6 2-Dimethoxyphosphorylsulfanyl-N-methylacetamide Omethoate C5H12NO4PS CNC(=O)CSP(=O)(OC)OC InChI=1S/C5H12NO4PS/c1-6-5(7)4-12-11(8,9-2)10-3/h4H2,1-3H3,(H,6,7) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro According to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No Acceptable Hamster (as animal) CHO Not reported yes without Positive RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is a metabolite of the substance Omethoate 214-197-8 1113-02-6 2-Dimethoxyphosphorylsulfanyl-N-methylacetamide Omethoate C5H12NO4PS CNC(=O)CSP(=O)(OC)OC InChI=1S/C5H12NO4PS/c1-6-5(7)4-12-11(8,9-2)10-3/h4H2,1-3H3,(H,6,7) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro According to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No Acceptable Hamster (as animal) CHO Not reported yes with Positive RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is a metabolite of the substance Omethoate 214-197-8 1113-02-6 2-Dimethoxyphosphorylsulfanyl-N-methylacetamide Omethoate C5H12NO4PS CNC(=O)CSP(=O)(OC)OC InChI=1S/C5H12NO4PS/c1-6-5(7)4-12-11(8,9-2)10-3/h4H2,1-3H3,(H,6,7) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Positive RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is a metabolite of the substance Omethoate 214-197-8 1113-02-6 2-Dimethoxyphosphorylsulfanyl-N-methylacetamide Omethoate C5H12NO4PS CNC(=O)CSP(=O)(OC)OC InChI=1S/C5H12NO4PS/c1-6-5(7)4-12-11(8,9-2)10-3/h4H2,1-3H3,(H,6,7) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 24.0000000000 h yes not applicable Negative indirect-toxicokinetic investigations RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is a metabolite of the substance Omethoate 214-197-8 1113-02-6 2-Dimethoxyphosphorylsulfanyl-N-methylacetamide Omethoate C5H12NO4PS CNC(=O)CSP(=O)(OC)OC InChI=1S/C5H12NO4PS/c1-6-5(7)4-12-11(8,9-2)10-3/h4H2,1-3H3,(H,6,7) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 48.0000000000 h yes not applicable Negative indirect-toxicokinetic investigations RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is a metabolite of the substance Omethoate 214-197-8 1113-02-6 2-Dimethoxyphosphorylsulfanyl-N-methylacetamide Omethoate C5H12NO4PS CNC(=O)CSP(=O)(OC)OC InChI=1S/C5H12NO4PS/c1-6-5(7)4-12-11(8,9-2)10-3/h4H2,1-3H3,(H,6,7) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 72.0000000000 h yes not applicable Negative indirect-toxicokinetic investigations RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is a metabolite of the substance Omethoate 214-197-8 1113-02-6 2-Dimethoxyphosphorylsulfanyl-N-methylacetamide Omethoate C5H12NO4PS CNC(=O)CSP(=O)(OC)OC InChI=1S/C5H12NO4PS/c1-6-5(7)4-12-11(8,9-2)10-3/h4H2,1-3H3,(H,6,7) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vivo No guideline available Not reported Not applicable Acceptable Hamster (as animal) Chinese 10 Male/Female intraperitoneal 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is a metabolite of the substance Omethoate 214-197-8 1113-02-6 2-Dimethoxyphosphorylsulfanyl-N-methylacetamide Omethoate C5H12NO4PS CNC(=O)CSP(=O)(OC)OC InChI=1S/C5H12NO4PS/c1-6-5(7)4-12-11(8,9-2)10-3/h4H2,1-3H3,(H,6,7) organic compound PubChem canonical SMILES PubChem InChI gene mutation mouse spot test in vivo Equivalent or similar to OECD Guideline 484 (Genetic Toxicology: Mouse Spot Test) Yes Acceptable House mouse (as animal) C57BL Female oral: gavage yes, concurrent vehicle not applicable Positive RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is a metabolite of the substance Omethoate 214-197-8 1113-02-6 2-Dimethoxyphosphorylsulfanyl-N-methylacetamide Omethoate C5H12NO4PS CNC(=O)CSP(=O)(OC)OC InChI=1S/C5H12NO4PS/c1-6-5(7)4-12-11(8,9-2)10-3/h4H2,1-3H3,(H,6,7) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Wistar 3 Male oral: gavage 16.0000000000 h yes not applicable Negative RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is a metabolite of the substance Omethoate 214-197-8 1113-02-6 2-Dimethoxyphosphorylsulfanyl-N-methylacetamide Omethoate C5H12NO4PS CNC(=O)CSP(=O)(OC)OC InChI=1S/C5H12NO4PS/c1-6-5(7)4-12-11(8,9-2)10-3/h4H2,1-3H3,(H,6,7) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Wistar 3 Male oral: gavage 2.0000000000 h yes not applicable Negative RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Dimethoate 200-480-3 60-51-5 single chemical entity Component is a metabolite of the substance Omethoate 214-197-8 1113-02-6 2-Dimethoxyphosphorylsulfanyl-N-methylacetamide Omethoate C5H12NO4PS CNC(=O)CSP(=O)(OC)OC InChI=1S/C5H12NO4PS/c1-6-5(7)4-12-11(8,9-2)10-3/h4H2,1-3H3,(H,6,7) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration dominant lethal assay in vivo According to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) No Acceptable House mouse (as animal) NMRI Male oral: gavage yes not applicable Negative RMS: The United Kingdom Dimethoate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate 10Jul2013 2013 doi:10.2903/j.efsa.2013.3233
+Teflubenzuron 83121-18-0 single chemical entity Component is identical to the substance Teflubenzuron 83121-18-0 N-[(3,5-dichloro-2,4-difluorophenyl)carbamoyl]-2,6-difluorobenzamide Teflubenzuron C14H6Cl2F4N2O2 O=C(NC(NC2=C(F)C(Cl)=C(F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F InChI=1S/C14H6Cl2F4N2O2/c15-5-4-8(12(20)10(16)11(5)19)21-14(24)22-13(23)9-6(17)2-1-3-7(9)18/h1-4H,(H2,21,22,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Teflubenzuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.184r
+Teflubenzuron 83121-18-0 single chemical entity Component is identical to the substance Teflubenzuron 83121-18-0 N-[(3,5-dichloro-2,4-difluorophenyl)carbamoyl]-2,6-difluorobenzamide Teflubenzuron C14H6Cl2F4N2O2 O=C(NC(NC2=C(F)C(Cl)=C(F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F InChI=1S/C14H6Cl2F4N2O2/c15-5-4-8(12(20)10(16)11(5)19)21-14(24)22-13(23)9-6(17)2-1-3-7(9)18/h1-4H,(H2,21,22,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Teflubenzuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.184r
+Teflubenzuron 83121-18-0 single chemical entity Component is identical to the substance Teflubenzuron 83121-18-0 N-[(3,5-dichloro-2,4-difluorophenyl)carbamoyl]-2,6-difluorobenzamide Teflubenzuron C14H6Cl2F4N2O2 O=C(NC(NC2=C(F)C(Cl)=C(F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F InChI=1S/C14H6Cl2F4N2O2/c15-5-4-8(12(20)10(16)11(5)19)21-14(24)22-13(23)9-6(17)2-1-3-7(9)18/h1-4H,(H2,21,22,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Teflubenzuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.184r
+Teflubenzuron 83121-18-0 single chemical entity Component is identical to the substance Teflubenzuron 83121-18-0 N-[(3,5-dichloro-2,4-difluorophenyl)carbamoyl]-2,6-difluorobenzamide Teflubenzuron C14H6Cl2F4N2O2 O=C(NC(NC2=C(F)C(Cl)=C(F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F InChI=1S/C14H6Cl2F4N2O2/c15-5-4-8(12(20)10(16)11(5)19)21-14(24)22-13(23)9-6(17)2-1-3-7(9)18/h1-4H,(H2,21,22,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Teflubenzuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.184r
+Teflubenzuron 83121-18-0 single chemical entity Component is identical to the substance Teflubenzuron 83121-18-0 N-[(3,5-dichloro-2,4-difluorophenyl)carbamoyl]-2,6-difluorobenzamide Teflubenzuron C14H6Cl2F4N2O2 O=C(NC(NC2=C(F)C(Cl)=C(F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F InChI=1S/C14H6Cl2F4N2O2/c15-5-4-8(12(20)10(16)11(5)19)21-14(24)22-13(23)9-6(17)2-1-3-7(9)18/h1-4H,(H2,21,22,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Teflubenzuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.184r
+Teflubenzuron 83121-18-0 single chemical entity Component is identical to the substance Teflubenzuron 83121-18-0 N-[(3,5-dichloro-2,4-difluorophenyl)carbamoyl]-2,6-difluorobenzamide Teflubenzuron C14H6Cl2F4N2O2 O=C(NC(NC2=C(F)C(Cl)=C(F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F InChI=1S/C14H6Cl2F4N2O2/c15-5-4-8(12(20)10(16)11(5)19)21-14(24)22-13(23)9-6(17)2-1-3-7(9)18/h1-4H,(H2,21,22,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Teflubenzuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.184r
+Teflubenzuron 83121-18-0 single chemical entity Component is identical to the substance Teflubenzuron 83121-18-0 N-[(3,5-dichloro-2,4-difluorophenyl)carbamoyl]-2,6-difluorobenzamide Teflubenzuron C14H6Cl2F4N2O2 O=C(NC(NC2=C(F)C(Cl)=C(F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F InChI=1S/C14H6Cl2F4N2O2/c15-5-4-8(12(20)10(16)11(5)19)21-14(24)22-13(23)9-6(17)2-1-3-7(9)18/h1-4H,(H2,21,22,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Teflubenzuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.184r
+Teflubenzuron 83121-18-0 single chemical entity Component is identical to the substance Teflubenzuron 83121-18-0 N-[(3,5-dichloro-2,4-difluorophenyl)carbamoyl]-2,6-difluorobenzamide Teflubenzuron C14H6Cl2F4N2O2 O=C(NC(NC2=C(F)C(Cl)=C(F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F InChI=1S/C14H6Cl2F4N2O2/c15-5-4-8(12(20)10(16)11(5)19)21-14(24)22-13(23)9-6(17)2-1-3-7(9)18/h1-4H,(H2,21,22,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Teflubenzuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.184r
+Teflubenzuron 83121-18-0 single chemical entity Component is identical to the substance Teflubenzuron 83121-18-0 N-[(3,5-dichloro-2,4-difluorophenyl)carbamoyl]-2,6-difluorobenzamide Teflubenzuron C14H6Cl2F4N2O2 O=C(NC(NC2=C(F)C(Cl)=C(F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F InChI=1S/C14H6Cl2F4N2O2/c15-5-4-8(12(20)10(16)11(5)19)21-14(24)22-13(23)9-6(17)2-1-3-7(9)18/h1-4H,(H2,21,22,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Teflubenzuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.184r
+Teflubenzuron 83121-18-0 single chemical entity Component is identical to the substance Teflubenzuron 83121-18-0 N-[(3,5-dichloro-2,4-difluorophenyl)carbamoyl]-2,6-difluorobenzamide Teflubenzuron C14H6Cl2F4N2O2 O=C(NC(NC2=C(F)C(Cl)=C(F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F InChI=1S/C14H6Cl2F4N2O2/c15-5-4-8(12(20)10(16)11(5)19)21-14(24)22-13(23)9-6(17)2-1-3-7(9)18/h1-4H,(H2,21,22,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Teflubenzuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.184r
+Teflubenzuron 83121-18-0 single chemical entity Component is identical to the substance Teflubenzuron 83121-18-0 N-[(3,5-dichloro-2,4-difluorophenyl)carbamoyl]-2,6-difluorobenzamide Teflubenzuron C14H6Cl2F4N2O2 O=C(NC(NC2=C(F)C(Cl)=C(F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F InChI=1S/C14H6Cl2F4N2O2/c15-5-4-8(12(20)10(16)11(5)19)21-14(24)22-13(23)9-6(17)2-1-3-7(9)18/h1-4H,(H2,21,22,23,24) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Teflubenzuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.184r
+Teflubenzuron 83121-18-0 single chemical entity Component is identical to the substance Teflubenzuron 83121-18-0 N-[(3,5-dichloro-2,4-difluorophenyl)carbamoyl]-2,6-difluorobenzamide Teflubenzuron C14H6Cl2F4N2O2 O=C(NC(NC2=C(F)C(Cl)=C(F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F InChI=1S/C14H6Cl2F4N2O2/c15-5-4-8(12(20)10(16)11(5)19)21-14(24)22-13(23)9-6(17)2-1-3-7(9)18/h1-4H,(H2,21,22,23,24) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Teflubenzuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.184r
+Teflubenzuron 83121-18-0 single chemical entity Component is identical to the substance Teflubenzuron 83121-18-0 N-[(3,5-dichloro-2,4-difluorophenyl)carbamoyl]-2,6-difluorobenzamide Teflubenzuron C14H6Cl2F4N2O2 O=C(NC(NC2=C(F)C(Cl)=C(F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F InChI=1S/C14H6Cl2F4N2O2/c15-5-4-8(12(20)10(16)11(5)19)21-14(24)22-13(23)9-6(17)2-1-3-7(9)18/h1-4H,(H2,21,22,23,24) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data without Negative RMS: The United Kingdom Teflubenzuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.184r
+Teflubenzuron 83121-18-0 single chemical entity Component is identical to the substance Teflubenzuron 83121-18-0 N-[(3,5-dichloro-2,4-difluorophenyl)carbamoyl]-2,6-difluorobenzamide Teflubenzuron C14H6Cl2F4N2O2 O=C(NC(NC2=C(F)C(Cl)=C(F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F InChI=1S/C14H6Cl2F4N2O2/c15-5-4-8(12(20)10(16)11(5)19)21-14(24)22-13(23)9-6(17)2-1-3-7(9)18/h1-4H,(H2,21,22,23,24) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data with Negative RMS: The United Kingdom Teflubenzuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.184r
+Teflubenzuron 83121-18-0 single chemical entity Component is identical to the substance Teflubenzuron 83121-18-0 N-[(3,5-dichloro-2,4-difluorophenyl)carbamoyl]-2,6-difluorobenzamide Teflubenzuron C14H6Cl2F4N2O2 O=C(NC(NC2=C(F)C(Cl)=C(F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F InChI=1S/C14H6Cl2F4N2O2/c15-5-4-8(12(20)10(16)11(5)19)21-14(24)22-13(23)9-6(17)2-1-3-7(9)18/h1-4H,(H2,21,22,23,24) organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Teflubenzuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.184r
+Teflubenzuron 83121-18-0 single chemical entity Component is identical to the substance Teflubenzuron 83121-18-0 N-[(3,5-dichloro-2,4-difluorophenyl)carbamoyl]-2,6-difluorobenzamide Teflubenzuron C14H6Cl2F4N2O2 O=C(NC(NC2=C(F)C(Cl)=C(F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F InChI=1S/C14H6Cl2F4N2O2/c15-5-4-8(12(20)10(16)11(5)19)21-14(24)22-13(23)9-6(17)2-1-3-7(9)18/h1-4H,(H2,21,22,23,24) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Not reported 12 Male/Female oral: gavage 72.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The United Kingdom Teflubenzuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.184r
+Teflubenzuron 83121-18-0 single chemical entity Component is identical to the substance Teflubenzuron 83121-18-0 N-[(3,5-dichloro-2,4-difluorophenyl)carbamoyl]-2,6-difluorobenzamide Teflubenzuron C14H6Cl2F4N2O2 O=C(NC(NC2=C(F)C(Cl)=C(F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F InChI=1S/C14H6Cl2F4N2O2/c15-5-4-8(12(20)10(16)11(5)19)21-14(24)22-13(23)9-6(17)2-1-3-7(9)18/h1-4H,(H2,21,22,23,24) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Not reported 12 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The United Kingdom Teflubenzuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.184r
+Teflubenzuron 83121-18-0 single chemical entity Component is identical to the substance Teflubenzuron 83121-18-0 N-[(3,5-dichloro-2,4-difluorophenyl)carbamoyl]-2,6-difluorobenzamide Teflubenzuron C14H6Cl2F4N2O2 O=C(NC(NC2=C(F)C(Cl)=C(F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F InChI=1S/C14H6Cl2F4N2O2/c15-5-4-8(12(20)10(16)11(5)19)21-14(24)22-13(23)9-6(17)2-1-3-7(9)18/h1-4H,(H2,21,22,23,24) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Not reported 12 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The United Kingdom Teflubenzuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.184r
+Teflubenzuron 83121-18-0 single chemical entity Component is a metabolite of the substance 3,5-dichloro-2,4-difluoroaniline 617-438-9 83121-15-7 3,5-dichloro-2,4-difluoroaniline Not in list C6H3Cl2F2N C1=C(C(=C(C(=C1Cl)F)Cl)F)N InChI=1S/C6H3Cl2F2N/c7-2-1-3(11)6(10)4(8)5(2)9/h1H,11H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: The United Kingdom Teflubenzuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.184r
+Teflubenzuron 83121-18-0 single chemical entity Component is a metabolite of the substance 3,5-dichloro-2,4-difluoroaniline 617-438-9 83121-15-7 3,5-dichloro-2,4-difluoroaniline Not in list C6H3Cl2F2N C1=C(C(=C(C(=C1Cl)F)Cl)F)N InChI=1S/C6H3Cl2F2N/c7-2-1-3(11)6(10)4(8)5(2)9/h1H,11H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The United Kingdom Teflubenzuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.184r
+Teflubenzuron 83121-18-0 single chemical entity Component is a metabolite of the substance 3,5-dichloro-2,4-difluoroaniline 617-438-9 83121-15-7 3,5-dichloro-2,4-difluoroaniline Not in list C6H3Cl2F2N C1=C(C(=C(C(=C1Cl)F)Cl)F)N InChI=1S/C6H3Cl2F2N/c7-2-1-3(11)6(10)4(8)5(2)9/h1H,11H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The United Kingdom Teflubenzuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.184r
+Teflubenzuron 83121-18-0 single chemical entity Component is a metabolite of the substance 3,5-dichloro-2,4-difluoroaniline 617-438-9 83121-15-7 3,5-dichloro-2,4-difluoroaniline Not in list C6H3Cl2F2N C1=C(C(=C(C(=C1Cl)F)Cl)F)N InChI=1S/C6H3Cl2F2N/c7-2-1-3(11)6(10)4(8)5(2)9/h1H,11H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The United Kingdom Teflubenzuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.184r
+Teflubenzuron 83121-18-0 single chemical entity Component is a metabolite of the substance 3,5-dichloro-2,4-difluoroaniline 617-438-9 83121-15-7 3,5-dichloro-2,4-difluoroaniline Not in list C6H3Cl2F2N C1=C(C(=C(C(=C1Cl)F)Cl)F)N InChI=1S/C6H3Cl2F2N/c7-2-1-3(11)6(10)4(8)5(2)9/h1H,11H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The United Kingdom Teflubenzuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.184r
+Teflubenzuron 83121-18-0 single chemical entity Component is a metabolite of the substance 3,5-dichloro-2,4-difluoroaniline 617-438-9 83121-15-7 3,5-dichloro-2,4-difluoroaniline Not in list C6H3Cl2F2N C1=C(C(=C(C(=C1Cl)F)Cl)F)N InChI=1S/C6H3Cl2F2N/c7-2-1-3(11)6(10)4(8)5(2)9/h1H,11H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The United Kingdom Teflubenzuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.184r
+Teflubenzuron 83121-18-0 single chemical entity Component is a metabolite of the substance 3,5-dichloro-2,4-difluoroaniline 617-438-9 83121-15-7 3,5-dichloro-2,4-difluoroaniline Not in list C6H3Cl2F2N C1=C(C(=C(C(=C1Cl)F)Cl)F)N InChI=1S/C6H3Cl2F2N/c7-2-1-3(11)6(10)4(8)5(2)9/h1H,11H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The United Kingdom Teflubenzuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.184r
+Teflubenzuron 83121-18-0 single chemical entity Component is a metabolite of the substance 3,5-dichloro-2,4-difluoroaniline 617-438-9 83121-15-7 3,5-dichloro-2,4-difluoroaniline Not in list C6H3Cl2F2N C1=C(C(=C(C(=C1Cl)F)Cl)F)N InChI=1S/C6H3Cl2F2N/c7-2-1-3(11)6(10)4(8)5(2)9/h1H,11H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The United Kingdom Teflubenzuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.184r
+Teflubenzuron 83121-18-0 single chemical entity Component is a metabolite of the substance 3,5-dichloro-2,4-difluoroaniline 617-438-9 83121-15-7 3,5-dichloro-2,4-difluoroaniline Not in list C6H3Cl2F2N C1=C(C(=C(C(=C1Cl)F)Cl)F)N InChI=1S/C6H3Cl2F2N/c7-2-1-3(11)6(10)4(8)5(2)9/h1H,11H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The United Kingdom Teflubenzuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.184r
+Teflubenzuron 83121-18-0 single chemical entity Component is a metabolite of the substance 3,5-dichloro-2,4-difluoroaniline 617-438-9 83121-15-7 3,5-dichloro-2,4-difluoroaniline Not in list C6H3Cl2F2N C1=C(C(=C(C(=C1Cl)F)Cl)F)N InChI=1S/C6H3Cl2F2N/c7-2-1-3(11)6(10)4(8)5(2)9/h1H,11H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: The United Kingdom Teflubenzuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.184r
+Teflubenzuron 83121-18-0 single chemical entity Component is a metabolite of the substance 3,5-dichloro-2,4-difluorophenylurea 1-(3,5-dichloro-2,4-difluorophenyl)urea Not in list C7H4Cl2F2N2O Clc1cc(NC(N)=O)c(F)c(Cl)c1F InChI=1/C7H4Cl2F2N2O/c8-2-1-3(13-7(12)14)6(11)4(9)5(2)10/h1H,(H3,12,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: The United Kingdom Teflubenzuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.184r
+Teflubenzuron 83121-18-0 single chemical entity Component is a metabolite of the substance 3,5-dichloro-2,4-difluorophenylurea 1-(3,5-dichloro-2,4-difluorophenyl)urea Not in list C7H4Cl2F2N2O Clc1cc(NC(N)=O)c(F)c(Cl)c1F InChI=1/C7H4Cl2F2N2O/c8-2-1-3(13-7(12)14)6(11)4(9)5(2)10/h1H,(H3,12,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The United Kingdom Teflubenzuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.184r
+Teflubenzuron 83121-18-0 single chemical entity Component is a metabolite of the substance 3,5-dichloro-2,4-difluorophenylurea 1-(3,5-dichloro-2,4-difluorophenyl)urea Not in list C7H4Cl2F2N2O Clc1cc(NC(N)=O)c(F)c(Cl)c1F InChI=1/C7H4Cl2F2N2O/c8-2-1-3(13-7(12)14)6(11)4(9)5(2)10/h1H,(H3,12,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The United Kingdom Teflubenzuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.184r
+Teflubenzuron 83121-18-0 single chemical entity Component is a metabolite of the substance 3,5-dichloro-2,4-difluorophenylurea 1-(3,5-dichloro-2,4-difluorophenyl)urea Not in list C7H4Cl2F2N2O Clc1cc(NC(N)=O)c(F)c(Cl)c1F InChI=1/C7H4Cl2F2N2O/c8-2-1-3(13-7(12)14)6(11)4(9)5(2)10/h1H,(H3,12,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The United Kingdom Teflubenzuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.184r
+Teflubenzuron 83121-18-0 single chemical entity Component is a metabolite of the substance 3,5-dichloro-2,4-difluorophenylurea 1-(3,5-dichloro-2,4-difluorophenyl)urea Not in list C7H4Cl2F2N2O Clc1cc(NC(N)=O)c(F)c(Cl)c1F InChI=1/C7H4Cl2F2N2O/c8-2-1-3(13-7(12)14)6(11)4(9)5(2)10/h1H,(H3,12,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The United Kingdom Teflubenzuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.184r
+Teflubenzuron 83121-18-0 single chemical entity Component is a metabolite of the substance 3,5-dichloro-2,4-difluorophenylurea 1-(3,5-dichloro-2,4-difluorophenyl)urea Not in list C7H4Cl2F2N2O Clc1cc(NC(N)=O)c(F)c(Cl)c1F InChI=1/C7H4Cl2F2N2O/c8-2-1-3(13-7(12)14)6(11)4(9)5(2)10/h1H,(H3,12,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: The United Kingdom Teflubenzuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.184r
+Teflubenzuron 83121-18-0 single chemical entity Component is a metabolite of the substance 3,5-dichloro-2,4-difluorophenylurea 1-(3,5-dichloro-2,4-difluorophenyl)urea Not in list C7H4Cl2F2N2O Clc1cc(NC(N)=O)c(F)c(Cl)c1F InChI=1/C7H4Cl2F2N2O/c8-2-1-3(13-7(12)14)6(11)4(9)5(2)10/h1H,(H3,12,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The United Kingdom Teflubenzuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.184r
+Teflubenzuron 83121-18-0 single chemical entity Component is a metabolite of the substance 3,5-dichloro-2,4-difluorophenylurea 1-(3,5-dichloro-2,4-difluorophenyl)urea Not in list C7H4Cl2F2N2O Clc1cc(NC(N)=O)c(F)c(Cl)c1F InChI=1/C7H4Cl2F2N2O/c8-2-1-3(13-7(12)14)6(11)4(9)5(2)10/h1H,(H3,12,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The United Kingdom Teflubenzuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.184r
+Teflubenzuron 83121-18-0 single chemical entity Component is a metabolite of the substance 3,5-dichloro-2,4-difluorophenylurea 1-(3,5-dichloro-2,4-difluorophenyl)urea Not in list C7H4Cl2F2N2O Clc1cc(NC(N)=O)c(F)c(Cl)c1F InChI=1/C7H4Cl2F2N2O/c8-2-1-3(13-7(12)14)6(11)4(9)5(2)10/h1H,(H3,12,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The United Kingdom Teflubenzuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.184r
+Teflubenzuron 83121-18-0 single chemical entity Component is a metabolite of the substance 3,5-dichloro-2,4-difluorophenylurea 1-(3,5-dichloro-2,4-difluorophenyl)urea Not in list C7H4Cl2F2N2O Clc1cc(NC(N)=O)c(F)c(Cl)c1F InChI=1/C7H4Cl2F2N2O/c8-2-1-3(13-7(12)14)6(11)4(9)5(2)10/h1H,(H3,12,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The United Kingdom Teflubenzuron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron 15Jan2009 2009 doi:10.2903/j.efsa.2009.184r
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is identical to the substance Glufosinate-ammonium 278-636-5 77182-82-2 ammonium (2RS)-2-amino-4-(methylphosphinato)butyric acid Glufosinate-ammonium C5H12NO4P.H3N CP(=O)(CCC(C(=O)[O-])N)O.[NH4+] InChI=1S/C5H12NO4P.H3N/c1-11(9,10)3-2-4(6)5(7)8;/h4H,2-3,6H2,1H3,(H,7,8)(H,9,10);1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is identical to the substance Glufosinate-ammonium 278-636-5 77182-82-2 ammonium (2RS)-2-amino-4-(methylphosphinato)butyric acid Glufosinate-ammonium C5H12NO4P.H3N CP(=O)(CCC(C(=O)[O-])N)O.[NH4+] InChI=1S/C5H12NO4P.H3N/c1-11(9,10)3-2-4(6)5(7)8;/h4H,2-3,6H2,1H3,(H,7,8)(H,9,10);1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is identical to the substance Glufosinate-ammonium 278-636-5 77182-82-2 ammonium (2RS)-2-amino-4-(methylphosphinato)butyric acid Glufosinate-ammonium C5H12NO4P.H3N CP(=O)(CCC(C(=O)[O-])N)O.[NH4+] InChI=1S/C5H12NO4P.H3N/c1-11(9,10)3-2-4(6)5(7)8;/h4H,2-3,6H2,1H3,(H,7,8)(H,9,10);1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is identical to the substance Glufosinate-ammonium 278-636-5 77182-82-2 ammonium (2RS)-2-amino-4-(methylphosphinato)butyric acid Glufosinate-ammonium C5H12NO4P.H3N CP(=O)(CCC(C(=O)[O-])N)O.[NH4+] InChI=1S/C5H12NO4P.H3N/c1-11(9,10)3-2-4(6)5(7)8;/h4H,2-3,6H2,1H3,(H,7,8)(H,9,10);1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is identical to the substance Glufosinate-ammonium 278-636-5 77182-82-2 ammonium (2RS)-2-amino-4-(methylphosphinato)butyric acid Glufosinate-ammonium C5H12NO4P.H3N CP(=O)(CCC(C(=O)[O-])N)O.[NH4+] InChI=1S/C5H12NO4P.H3N/c1-11(9,10)3-2-4(6)5(7)8;/h4H,2-3,6H2,1H3,(H,7,8)(H,9,10);1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is identical to the substance Glufosinate-ammonium 278-636-5 77182-82-2 ammonium (2RS)-2-amino-4-(methylphosphinato)butyric acid Glufosinate-ammonium C5H12NO4P.H3N CP(=O)(CCC(C(=O)[O-])N)O.[NH4+] InChI=1S/C5H12NO4P.H3N/c1-11(9,10)3-2-4(6)5(7)8;/h4H,2-3,6H2,1H3,(H,7,8)(H,9,10);1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is identical to the substance Glufosinate-ammonium 278-636-5 77182-82-2 ammonium (2RS)-2-amino-4-(methylphosphinato)butyric acid Glufosinate-ammonium C5H12NO4P.H3N CP(=O)(CCC(C(=O)[O-])N)O.[NH4+] InChI=1S/C5H12NO4P.H3N/c1-11(9,10)3-2-4(6)5(7)8;/h4H,2-3,6H2,1H3,(H,7,8)(H,9,10);1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is identical to the substance Glufosinate-ammonium 278-636-5 77182-82-2 ammonium (2RS)-2-amino-4-(methylphosphinato)butyric acid Glufosinate-ammonium C5H12NO4P.H3N CP(=O)(CCC(C(=O)[O-])N)O.[NH4+] InChI=1S/C5H12NO4P.H3N/c1-11(9,10)3-2-4(6)5(7)8;/h4H,2-3,6H2,1H3,(H,7,8)(H,9,10);1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is identical to the substance Glufosinate-ammonium 278-636-5 77182-82-2 ammonium (2RS)-2-amino-4-(methylphosphinato)butyric acid Glufosinate-ammonium C5H12NO4P.H3N CP(=O)(CCC(C(=O)[O-])N)O.[NH4+] InChI=1S/C5H12NO4P.H3N/c1-11(9,10)3-2-4(6)5(7)8;/h4H,2-3,6H2,1H3,(H,7,8)(H,9,10);1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is identical to the substance Glufosinate-ammonium 278-636-5 77182-82-2 ammonium (2RS)-2-amino-4-(methylphosphinato)butyric acid Glufosinate-ammonium C5H12NO4P.H3N CP(=O)(CCC(C(=O)[O-])N)O.[NH4+] InChI=1S/C5H12NO4P.H3N/c1-11(9,10)3-2-4(6)5(7)8;/h4H,2-3,6H2,1H3,(H,7,8)(H,9,10);1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is identical to the substance Glufosinate-ammonium 278-636-5 77182-82-2 ammonium (2RS)-2-amino-4-(methylphosphinato)butyric acid Glufosinate-ammonium C5H12NO4P.H3N CP(=O)(CCC(C(=O)[O-])N)O.[NH4+] InChI=1S/C5H12NO4P.H3N/c1-11(9,10)3-2-4(6)5(7)8;/h4H,2-3,6H2,1H3,(H,7,8)(H,9,10);1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation yeast cytogenetic assay in vitro No guideline available Not reported Yes Acceptable Saccharomyces cerevisiae (as organism) D4 Not reported yes without Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is identical to the substance Glufosinate-ammonium 278-636-5 77182-82-2 ammonium (2RS)-2-amino-4-(methylphosphinato)butyric acid Glufosinate-ammonium C5H12NO4P.H3N CP(=O)(CCC(C(=O)[O-])N)O.[NH4+] InChI=1S/C5H12NO4P.H3N/c1-11(9,10)3-2-4(6)5(7)8;/h4H,2-3,6H2,1H3,(H,7,8)(H,9,10);1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation yeast cytogenetic assay in vitro No guideline available Not reported Yes Acceptable Saccharomyces cerevisiae (as organism) D4 Not reported yes with Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is identical to the substance Glufosinate-ammonium 278-636-5 77182-82-2 ammonium (2RS)-2-amino-4-(methylphosphinato)butyric acid Glufosinate-ammonium C5H12NO4P.H3N CP(=O)(CCC(C(=O)[O-])N)O.[NH4+] InChI=1S/C5H12NO4P.H3N/c1-11(9,10)3-2-4(6)5(7)8;/h4H,2-3,6H2,1H3,(H,7,8)(H,9,10);1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Schizosaccharomyces pombe (as organism) Not reported Not reported yes with Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is identical to the substance Glufosinate-ammonium 278-636-5 77182-82-2 ammonium (2RS)-2-amino-4-(methylphosphinato)butyric acid Glufosinate-ammonium C5H12NO4P.H3N CP(=O)(CCC(C(=O)[O-])N)O.[NH4+] InChI=1S/C5H12NO4P.H3N/c1-11(9,10)3-2-4(6)5(7)8;/h4H,2-3,6H2,1H3,(H,7,8)(H,9,10);1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Schizosaccharomyces pombe (as organism) Not reported Not reported yes without Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is identical to the substance Glufosinate-ammonium 278-636-5 77182-82-2 ammonium (2RS)-2-amino-4-(methylphosphinato)butyric acid Glufosinate-ammonium C5H12NO4P.H3N CP(=O)(CCC(C(=O)[O-])N)O.[NH4+] InChI=1S/C5H12NO4P.H3N/c1-11(9,10)3-2-4(6)5(7)8;/h4H,2-3,6H2,1H3,(H,7,8)(H,9,10);1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent no treatment without Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is identical to the substance Glufosinate-ammonium 278-636-5 77182-82-2 ammonium (2RS)-2-amino-4-(methylphosphinato)butyric acid Glufosinate-ammonium C5H12NO4P.H3N CP(=O)(CCC(C(=O)[O-])N)O.[NH4+] InChI=1S/C5H12NO4P.H3N/c1-11(9,10)3-2-4(6)5(7)8;/h4H,2-3,6H2,1H3,(H,7,8)(H,9,10);1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent no treatment with Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is identical to the substance Glufosinate-ammonium 278-636-5 77182-82-2 ammonium (2RS)-2-amino-4-(methylphosphinato)butyric acid Glufosinate-ammonium C5H12NO4P.H3N CP(=O)(CCC(C(=O)[O-])N)O.[NH4+] InChI=1S/C5H12NO4P.H3N/c1-11(9,10)3-2-4(6)5(7)8;/h4H,2-3,6H2,1H3,(H,7,8)(H,9,10);1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is identical to the substance Glufosinate-ammonium 278-636-5 77182-82-2 ammonium (2RS)-2-amino-4-(methylphosphinato)butyric acid Glufosinate-ammonium C5H12NO4P.H3N CP(=O)(CCC(C(=O)[O-])N)O.[NH4+] InChI=1S/C5H12NO4P.H3N/c1-11(9,10)3-2-4(6)5(7)8;/h4H,2-3,6H2,1H3,(H,7,8)(H,9,10);1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is identical to the substance Glufosinate-ammonium 278-636-5 77182-82-2 ammonium (2RS)-2-amino-4-(methylphosphinato)butyric acid Glufosinate-ammonium C5H12NO4P.H3N CP(=O)(CCC(C(=O)[O-])N)O.[NH4+] InChI=1S/C5H12NO4P.H3N/c1-11(9,10)3-2-4(6)5(7)8;/h4H,2-3,6H2,1H3,(H,7,8)(H,9,10);1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent no treatment with Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is identical to the substance Glufosinate-ammonium 278-636-5 77182-82-2 ammonium (2RS)-2-amino-4-(methylphosphinato)butyric acid Glufosinate-ammonium C5H12NO4P.H3N CP(=O)(CCC(C(=O)[O-])N)O.[NH4+] InChI=1S/C5H12NO4P.H3N/c1-11(9,10)3-2-4(6)5(7)8;/h4H,2-3,6H2,1H3,(H,7,8)(H,9,10);1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent no treatment without Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is identical to the substance Glufosinate-ammonium 278-636-5 77182-82-2 ammonium (2RS)-2-amino-4-(methylphosphinato)butyric acid Glufosinate-ammonium C5H12NO4P.H3N CP(=O)(CCC(C(=O)[O-])N)O.[NH4+] InChI=1S/C5H12NO4P.H3N/c1-11(9,10)3-2-4(6)5(7)8;/h4H,2-3,6H2,1H3,(H,7,8)(H,9,10);1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 30 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is identical to the substance Glufosinate-ammonium 278-636-5 77182-82-2 ammonium (2RS)-2-amino-4-(methylphosphinato)butyric acid Glufosinate-ammonium C5H12NO4P.H3N CP(=O)(CCC(C(=O)[O-])N)O.[NH4+] InChI=1S/C5H12NO4P.H3N/c1-11(9,10)3-2-4(6)5(7)8;/h4H,2-3,6H2,1H3,(H,7,8)(H,9,10);1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 30 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is identical to the substance Glufosinate-ammonium 278-636-5 77182-82-2 ammonium (2RS)-2-amino-4-(methylphosphinato)butyric acid Glufosinate-ammonium C5H12NO4P.H3N CP(=O)(CCC(C(=O)[O-])N)O.[NH4+] InChI=1S/C5H12NO4P.H3N/c1-11(9,10)3-2-4(6)5(7)8;/h4H,2-3,6H2,1H3,(H,7,8)(H,9,10);1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 30 Male/Female oral: gavage 72.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is identical to the substance Glufosinate-ammonium 278-636-5 77182-82-2 ammonium (2RS)-2-amino-4-(methylphosphinato)butyric acid Glufosinate-ammonium C5H12NO4P.H3N CP(=O)(CCC(C(=O)[O-])N)O.[NH4+] InChI=1S/C5H12NO4P.H3N/c1-11(9,10)3-2-4(6)5(7)8;/h4H,2-3,6H2,1H3,(H,7,8)(H,9,10);1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes without Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance N-acetyl-glufosinate 73634-73-8 2-acetamido-4-[hydroxy(methyl)phosphoryl]butanoic acid Not in list C7H14NO5P CC(=O)NC(CCP(=O)(C)O)C(=O)O InChI=1S/C7H14NO5P/c1-5(9)8-6(7(10)11)3-4-14(2,12)13/h6H,3-4H2,1-2H3,(H,8,9)(H,10,11)(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance N-acetyl-glufosinate 73634-73-8 2-acetamido-4-[hydroxy(methyl)phosphoryl]butanoic acid Not in list C7H14NO5P CC(=O)NC(CCP(=O)(C)O)C(=O)O InChI=1S/C7H14NO5P/c1-5(9)8-6(7(10)11)3-4-14(2,12)13/h6H,3-4H2,1-2H3,(H,8,9)(H,10,11)(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance N-acetyl-glufosinate 73634-73-8 2-acetamido-4-[hydroxy(methyl)phosphoryl]butanoic acid Not in list C7H14NO5P CC(=O)NC(CCP(=O)(C)O)C(=O)O InChI=1S/C7H14NO5P/c1-5(9)8-6(7(10)11)3-4-14(2,12)13/h6H,3-4H2,1-2H3,(H,8,9)(H,10,11)(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance N-acetyl-glufosinate 73634-73-8 2-acetamido-4-[hydroxy(methyl)phosphoryl]butanoic acid Not in list C7H14NO5P CC(=O)NC(CCP(=O)(C)O)C(=O)O InChI=1S/C7H14NO5P/c1-5(9)8-6(7(10)11)3-4-14(2,12)13/h6H,3-4H2,1-2H3,(H,8,9)(H,10,11)(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance N-acetyl-glufosinate 73634-73-8 2-acetamido-4-[hydroxy(methyl)phosphoryl]butanoic acid Not in list C7H14NO5P CC(=O)NC(CCP(=O)(C)O)C(=O)O InChI=1S/C7H14NO5P/c1-5(9)8-6(7(10)11)3-4-14(2,12)13/h6H,3-4H2,1-2H3,(H,8,9)(H,10,11)(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance N-acetyl-glufosinate 73634-73-8 2-acetamido-4-[hydroxy(methyl)phosphoryl]butanoic acid Not in list C7H14NO5P CC(=O)NC(CCP(=O)(C)O)C(=O)O InChI=1S/C7H14NO5P/c1-5(9)8-6(7(10)11)3-4-14(2,12)13/h6H,3-4H2,1-2H3,(H,8,9)(H,10,11)(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance N-acetyl-glufosinate 73634-73-8 2-acetamido-4-[hydroxy(methyl)phosphoryl]butanoic acid Not in list C7H14NO5P CC(=O)NC(CCP(=O)(C)O)C(=O)O InChI=1S/C7H14NO5P/c1-5(9)8-6(7(10)11)3-4-14(2,12)13/h6H,3-4H2,1-2H3,(H,8,9)(H,10,11)(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance N-acetyl-glufosinate 73634-73-8 2-acetamido-4-[hydroxy(methyl)phosphoryl]butanoic acid Not in list C7H14NO5P CC(=O)NC(CCP(=O)(C)O)C(=O)O InChI=1S/C7H14NO5P/c1-5(9)8-6(7(10)11)3-4-14(2,12)13/h6H,3-4H2,1-2H3,(H,8,9)(H,10,11)(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance N-acetyl-glufosinate 73634-73-8 2-acetamido-4-[hydroxy(methyl)phosphoryl]butanoic acid Not in list C7H14NO5P CC(=O)NC(CCP(=O)(C)O)C(=O)O InChI=1S/C7H14NO5P/c1-5(9)8-6(7(10)11)3-4-14(2,12)13/h6H,3-4H2,1-2H3,(H,8,9)(H,10,11)(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance N-acetyl-glufosinate 73634-73-8 2-acetamido-4-[hydroxy(methyl)phosphoryl]butanoic acid Not in list C7H14NO5P CC(=O)NC(CCP(=O)(C)O)C(=O)O InChI=1S/C7H14NO5P/c1-5(9)8-6(7(10)11)3-4-14(2,12)13/h6H,3-4H2,1-2H3,(H,8,9)(H,10,11)(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance N-acetyl-glufosinate 73634-73-8 2-acetamido-4-[hydroxy(methyl)phosphoryl]butanoic acid Not in list C7H14NO5P CC(=O)NC(CCP(=O)(C)O)C(=O)O InChI=1S/C7H14NO5P/c1-5(9)8-6(7(10)11)3-4-14(2,12)13/h6H,3-4H2,1-2H3,(H,8,9)(H,10,11)(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance N-acetyl-glufosinate 73634-73-8 2-acetamido-4-[hydroxy(methyl)phosphoryl]butanoic acid Not in list C7H14NO5P CC(=O)NC(CCP(=O)(C)O)C(=O)O InChI=1S/C7H14NO5P/c1-5(9)8-6(7(10)11)3-4-14(2,12)13/h6H,3-4H2,1-2H3,(H,8,9)(H,10,11)(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance N-acetyl-glufosinate 73634-73-8 2-acetamido-4-[hydroxy(methyl)phosphoryl]butanoic acid Not in list C7H14NO5P CC(=O)NC(CCP(=O)(C)O)C(=O)O InChI=1S/C7H14NO5P/c1-5(9)8-6(7(10)11)3-4-14(2,12)13/h6H,3-4H2,1-2H3,(H,8,9)(H,10,11)(H,12,13) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance N-acetyl-glufosinate 73634-73-8 2-acetamido-4-[hydroxy(methyl)phosphoryl]butanoic acid Not in list C7H14NO5P CC(=O)NC(CCP(=O)(C)O)C(=O)O InChI=1S/C7H14NO5P/c1-5(9)8-6(7(10)11)3-4-14(2,12)13/h6H,3-4H2,1-2H3,(H,8,9)(H,10,11)(H,12,13) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance N-acetyl-glufosinate 73634-73-8 2-acetamido-4-[hydroxy(methyl)phosphoryl]butanoic acid Not in list C7H14NO5P CC(=O)NC(CCP(=O)(C)O)C(=O)O InChI=1S/C7H14NO5P/c1-5(9)8-6(7(10)11)3-4-14(2,12)13/h6H,3-4H2,1-2H3,(H,8,9)(H,10,11)(H,12,13) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported no data with Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance N-acetyl-glufosinate 73634-73-8 2-acetamido-4-[hydroxy(methyl)phosphoryl]butanoic acid Not in list C7H14NO5P CC(=O)NC(CCP(=O)(C)O)C(=O)O InChI=1S/C7H14NO5P/c1-5(9)8-6(7(10)11)3-4-14(2,12)13/h6H,3-4H2,1-2H3,(H,8,9)(H,10,11)(H,12,13) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported no data without Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance N-acetyl-glufosinate 73634-73-8 2-acetamido-4-[hydroxy(methyl)phosphoryl]butanoic acid Not in list C7H14NO5P CC(=O)NC(CCP(=O)(C)O)C(=O)O InChI=1S/C7H14NO5P/c1-5(9)8-6(7(10)11)3-4-14(2,12)13/h6H,3-4H2,1-2H3,(H,8,9)(H,10,11)(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance N-acetyl-glufosinate 73634-73-8 2-acetamido-4-[hydroxy(methyl)phosphoryl]butanoic acid Not in list C7H14NO5P CC(=O)NC(CCP(=O)(C)O)C(=O)O InChI=1S/C7H14NO5P/c1-5(9)8-6(7(10)11)3-4-14(2,12)13/h6H,3-4H2,1-2H3,(H,8,9)(H,10,11)(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance N-acetyl-glufosinate 73634-73-8 2-acetamido-4-[hydroxy(methyl)phosphoryl]butanoic acid Not in list C7H14NO5P CC(=O)NC(CCP(=O)(C)O)C(=O)O InChI=1S/C7H14NO5P/c1-5(9)8-6(7(10)11)3-4-14(2,12)13/h6H,3-4H2,1-2H3,(H,8,9)(H,10,11)(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data with Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance N-acetyl-glufosinate 73634-73-8 2-acetamido-4-[hydroxy(methyl)phosphoryl]butanoic acid Not in list C7H14NO5P CC(=O)NC(CCP(=O)(C)O)C(=O)O InChI=1S/C7H14NO5P/c1-5(9)8-6(7(10)11)3-4-14(2,12)13/h6H,3-4H2,1-2H3,(H,8,9)(H,10,11)(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data without Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance N-acetyl-glufosinate 73634-73-8 2-acetamido-4-[hydroxy(methyl)phosphoryl]butanoic acid Not in list C7H14NO5P CC(=O)NC(CCP(=O)(C)O)C(=O)O InChI=1S/C7H14NO5P/c1-5(9)8-6(7(10)11)3-4-14(2,12)13/h6H,3-4H2,1-2H3,(H,8,9)(H,10,11)(H,12,13) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Human (as organism) alveolar basal epithelial cells (A549) Not reported yes, concurrent vehicle with Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance N-acetyl-glufosinate 73634-73-8 2-acetamido-4-[hydroxy(methyl)phosphoryl]butanoic acid Not in list C7H14NO5P CC(=O)NC(CCP(=O)(C)O)C(=O)O InChI=1S/C7H14NO5P/c1-5(9)8-6(7(10)11)3-4-14(2,12)13/h6H,3-4H2,1-2H3,(H,8,9)(H,10,11)(H,12,13) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Human (as organism) alveolar basal epithelial cells (A549) Not reported yes, concurrent vehicle without Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance N-acetyl-glufosinate 73634-73-8 2-acetamido-4-[hydroxy(methyl)phosphoryl]butanoic acid Not in list C7H14NO5P CC(=O)NC(CCP(=O)(C)O)C(=O)O InChI=1S/C7H14NO5P/c1-5(9)8-6(7(10)11)3-4-14(2,12)13/h6H,3-4H2,1-2H3,(H,8,9)(H,10,11)(H,12,13) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Human (as organism) alveolar basal epithelial cells (A549) Not reported yes, concurrent vehicle with Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance N-acetyl-glufosinate 73634-73-8 2-acetamido-4-[hydroxy(methyl)phosphoryl]butanoic acid Not in list C7H14NO5P CC(=O)NC(CCP(=O)(C)O)C(=O)O InChI=1S/C7H14NO5P/c1-5(9)8-6(7(10)11)3-4-14(2,12)13/h6H,3-4H2,1-2H3,(H,8,9)(H,10,11)(H,12,13) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Human (as organism) alveolar basal epithelial cells (A549) Not reported yes, concurrent vehicle without Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance N-acetyl-glufosinate 73634-73-8 2-acetamido-4-[hydroxy(methyl)phosphoryl]butanoic acid Not in list C7H14NO5P CC(=O)NC(CCP(=O)(C)O)C(=O)O InChI=1S/C7H14NO5P/c1-5(9)8-6(7(10)11)3-4-14(2,12)13/h6H,3-4H2,1-2H3,(H,8,9)(H,10,11)(H,12,13) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Not reported No data oral: gavage 24.0000000000 h yes not applicable Negative no evidence RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance N-acetyl-glufosinate 73634-73-8 2-acetamido-4-[hydroxy(methyl)phosphoryl]butanoic acid Not in list C7H14NO5P CC(=O)NC(CCP(=O)(C)O)C(=O)O InChI=1S/C7H14NO5P/c1-5(9)8-6(7(10)11)3-4-14(2,12)13/h6H,3-4H2,1-2H3,(H,8,9)(H,10,11)(H,12,13) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Not reported No data oral: gavage 48.0000000000 h yes not applicable Negative no evidence RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance N-acetyl-glufosinate 73634-73-8 2-acetamido-4-[hydroxy(methyl)phosphoryl]butanoic acid Not in list C7H14NO5P CC(=O)NC(CCP(=O)(C)O)C(=O)O InChI=1S/C7H14NO5P/c1-5(9)8-6(7(10)11)3-4-14(2,12)13/h6H,3-4H2,1-2H3,(H,8,9)(H,10,11)(H,12,13) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Not reported No data oral: gavage 72.0000000000 h yes not applicable Negative no evidence RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance 3-metylphosphinico-propionic acid 3-[hydroxy(methyl)phosphoryl]propanoic acid Not in list C4H9O4P O=C(O)CCP(C)(=O)O InChI=1/C4H9O4P/c1-9(7,8)3-2-4(5)6/h2-3H2,1H3,(H,5,6)(H,7,8) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance 3-metylphosphinico-propionic acid 3-[hydroxy(methyl)phosphoryl]propanoic acid Not in list C4H9O4P O=C(O)CCP(C)(=O)O InChI=1/C4H9O4P/c1-9(7,8)3-2-4(5)6/h2-3H2,1H3,(H,5,6)(H,7,8) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance 3-metylphosphinico-propionic acid 3-[hydroxy(methyl)phosphoryl]propanoic acid Not in list C4H9O4P O=C(O)CCP(C)(=O)O InChI=1/C4H9O4P/c1-9(7,8)3-2-4(5)6/h2-3H2,1H3,(H,5,6)(H,7,8) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance 3-metylphosphinico-propionic acid 3-[hydroxy(methyl)phosphoryl]propanoic acid Not in list C4H9O4P O=C(O)CCP(C)(=O)O InChI=1/C4H9O4P/c1-9(7,8)3-2-4(5)6/h2-3H2,1H3,(H,5,6)(H,7,8) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance 3-metylphosphinico-propionic acid 3-[hydroxy(methyl)phosphoryl]propanoic acid Not in list C4H9O4P O=C(O)CCP(C)(=O)O InChI=1/C4H9O4P/c1-9(7,8)3-2-4(5)6/h2-3H2,1H3,(H,5,6)(H,7,8) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance 3-metylphosphinico-propionic acid 3-[hydroxy(methyl)phosphoryl]propanoic acid Not in list C4H9O4P O=C(O)CCP(C)(=O)O InChI=1/C4H9O4P/c1-9(7,8)3-2-4(5)6/h2-3H2,1H3,(H,5,6)(H,7,8) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance 3-metylphosphinico-propionic acid 3-[hydroxy(methyl)phosphoryl]propanoic acid Not in list C4H9O4P O=C(O)CCP(C)(=O)O InChI=1/C4H9O4P/c1-9(7,8)3-2-4(5)6/h2-3H2,1H3,(H,5,6)(H,7,8) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance 3-metylphosphinico-propionic acid 3-[hydroxy(methyl)phosphoryl]propanoic acid Not in list C4H9O4P O=C(O)CCP(C)(=O)O InChI=1/C4H9O4P/c1-9(7,8)3-2-4(5)6/h2-3H2,1H3,(H,5,6)(H,7,8) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance 3-metylphosphinico-propionic acid 3-[hydroxy(methyl)phosphoryl]propanoic acid Not in list C4H9O4P O=C(O)CCP(C)(=O)O InChI=1/C4H9O4P/c1-9(7,8)3-2-4(5)6/h2-3H2,1H3,(H,5,6)(H,7,8) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance 3-metylphosphinico-propionic acid 3-[hydroxy(methyl)phosphoryl]propanoic acid Not in list C4H9O4P O=C(O)CCP(C)(=O)O InChI=1/C4H9O4P/c1-9(7,8)3-2-4(5)6/h2-3H2,1H3,(H,5,6)(H,7,8) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance 3-metylphosphinico-propionic acid 3-[hydroxy(methyl)phosphoryl]propanoic acid Not in list C4H9O4P O=C(O)CCP(C)(=O)O InChI=1/C4H9O4P/c1-9(7,8)3-2-4(5)6/h2-3H2,1H3,(H,5,6)(H,7,8) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance 3-metylphosphinico-propionic acid 3-[hydroxy(methyl)phosphoryl]propanoic acid Not in list C4H9O4P O=C(O)CCP(C)(=O)O InChI=1/C4H9O4P/c1-9(7,8)3-2-4(5)6/h2-3H2,1H3,(H,5,6)(H,7,8) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance 3-metylphosphinico-propionic acid 3-[hydroxy(methyl)phosphoryl]propanoic acid Not in list C4H9O4P O=C(O)CCP(C)(=O)O InChI=1/C4H9O4P/c1-9(7,8)3-2-4(5)6/h2-3H2,1H3,(H,5,6)(H,7,8) organic compound Other Other gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Schizosaccharomyces pombe (as organism) Not reported yes without Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance 3-metylphosphinico-propionic acid 3-[hydroxy(methyl)phosphoryl]propanoic acid Not in list C4H9O4P O=C(O)CCP(C)(=O)O InChI=1/C4H9O4P/c1-9(7,8)3-2-4(5)6/h2-3H2,1H3,(H,5,6)(H,7,8) organic compound Other Other gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Schizosaccharomyces pombe (as organism) Not reported yes with Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance 3-metylphosphinico-propionic acid 3-[hydroxy(methyl)phosphoryl]propanoic acid Not in list C4H9O4P O=C(O)CCP(C)(=O)O InChI=1/C4H9O4P/c1-9(7,8)3-2-4(5)6/h2-3H2,1H3,(H,5,6)(H,7,8) organic compound Other Other chromosome aberration other in vitro No guideline available Not reported Not applicable Acceptable Saccharomyces cerevisiae (as organism) D4 Not reported yes without Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance 3-metylphosphinico-propionic acid 3-[hydroxy(methyl)phosphoryl]propanoic acid Not in list C4H9O4P O=C(O)CCP(C)(=O)O InChI=1/C4H9O4P/c1-9(7,8)3-2-4(5)6/h2-3H2,1H3,(H,5,6)(H,7,8) organic compound Other Other chromosome aberration other in vitro No guideline available Not reported Not applicable Acceptable Saccharomyces cerevisiae (as organism) D4 Not reported yes with Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance 3-metylphosphinico-propionic acid 3-[hydroxy(methyl)phosphoryl]propanoic acid Not in list C4H9O4P O=C(O)CCP(C)(=O)O InChI=1/C4H9O4P/c1-9(7,8)3-2-4(5)6/h2-3H2,1H3,(H,5,6)(H,7,8) organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Human (as organism) alveolar basal epithelial cells (A549) Not reported yes without Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance 3-metylphosphinico-propionic acid 3-[hydroxy(methyl)phosphoryl]propanoic acid Not in list C4H9O4P O=C(O)CCP(C)(=O)O InChI=1/C4H9O4P/c1-9(7,8)3-2-4(5)6/h2-3H2,1H3,(H,5,6)(H,7,8) organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Human (as organism) alveolar basal epithelial cells (A549) Not reported yes with Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance 3-metylphosphinico-propionic acid 3-[hydroxy(methyl)phosphoryl]propanoic acid Not in list C4H9O4P O=C(O)CCP(C)(=O)O InChI=1/C4H9O4P/c1-9(7,8)3-2-4(5)6/h2-3H2,1H3,(H,5,6)(H,7,8) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes without Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance 3-metylphosphinico-propionic acid 3-[hydroxy(methyl)phosphoryl]propanoic acid Not in list C4H9O4P O=C(O)CCP(C)(=O)O InChI=1/C4H9O4P/c1-9(7,8)3-2-4(5)6/h2-3H2,1H3,(H,5,6)(H,7,8) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes with Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance 3-metylphosphinico-propionic acid 3-[hydroxy(methyl)phosphoryl]propanoic acid Not in list C4H9O4P O=C(O)CCP(C)(=O)O InChI=1/C4H9O4P/c1-9(7,8)3-2-4(5)6/h2-3H2,1H3,(H,5,6)(H,7,8) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance 3-metylphosphinico-propionic acid 3-[hydroxy(methyl)phosphoryl]propanoic acid Not in list C4H9O4P O=C(O)CCP(C)(=O)O InChI=1/C4H9O4P/c1-9(7,8)3-2-4(5)6/h2-3H2,1H3,(H,5,6)(H,7,8) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance 3-metylphosphinico-propionic acid 3-[hydroxy(methyl)phosphoryl]propanoic acid Not in list C4H9O4P O=C(O)CCP(C)(=O)O InChI=1/C4H9O4P/c1-9(7,8)3-2-4(5)6/h2-3H2,1H3,(H,5,6)(H,7,8) organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Hamster (as animal) Chinese 12 Male/Female oral: gavage 6.0000000000 h yes not applicable Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance 3-metylphosphinico-propionic acid 3-[hydroxy(methyl)phosphoryl]propanoic acid Not in list C4H9O4P O=C(O)CCP(C)(=O)O InChI=1/C4H9O4P/c1-9(7,8)3-2-4(5)6/h2-3H2,1H3,(H,5,6)(H,7,8) organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Hamster (as animal) Chinese 12 Male/Female oral: gavage 24.0000000000 h yes not applicable Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance 3-metylphosphinico-propionic acid 3-[hydroxy(methyl)phosphoryl]propanoic acid Not in list C4H9O4P O=C(O)CCP(C)(=O)O InChI=1/C4H9O4P/c1-9(7,8)3-2-4(5)6/h2-3H2,1H3,(H,5,6)(H,7,8) organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Hamster (as animal) Chinese 12 Male/Female oral: gavage 48.0000000000 h yes not applicable Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance 3-metylphosphinico-propionic acid 3-[hydroxy(methyl)phosphoryl]propanoic acid Not in list C4H9O4P O=C(O)CCP(C)(=O)O InChI=1/C4H9O4P/c1-9(7,8)3-2-4(5)6/h2-3H2,1H3,(H,5,6)(H,7,8) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 72.0000000000 h yes not applicable Negative indirect evidence-systemic toxicity RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance 3-metylphosphinico-propionic acid 3-[hydroxy(methyl)phosphoryl]propanoic acid Not in list C4H9O4P O=C(O)CCP(C)(=O)O InChI=1/C4H9O4P/c1-9(7,8)3-2-4(5)6/h2-3H2,1H3,(H,5,6)(H,7,8) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 48.0000000000 h yes not applicable Negative indirect evidence-systemic toxicity RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance 3-metylphosphinico-propionic acid 3-[hydroxy(methyl)phosphoryl]propanoic acid Not in list C4H9O4P O=C(O)CCP(C)(=O)O InChI=1/C4H9O4P/c1-9(7,8)3-2-4(5)6/h2-3H2,1H3,(H,5,6)(H,7,8) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 24.0000000000 h yes not applicable Negative indirect evidence-systemic toxicity RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance 2-methylphosphinico-acetic acid [hydroxy(methyl)phosphoryl]acetic acid Not in list C3H7O4P O=C(O)CP(C)(=O)O InChI=1/C3H7O4P/c1-8(6,7)2-3(4)5/h2H2,1H3,(H,4,5)(H,6,7) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance 2-methylphosphinico-acetic acid [hydroxy(methyl)phosphoryl]acetic acid Not in list C3H7O4P O=C(O)CP(C)(=O)O InChI=1/C3H7O4P/c1-8(6,7)2-3(4)5/h2H2,1H3,(H,4,5)(H,6,7) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance 2-methylphosphinico-acetic acid [hydroxy(methyl)phosphoryl]acetic acid Not in list C3H7O4P O=C(O)CP(C)(=O)O InChI=1/C3H7O4P/c1-8(6,7)2-3(4)5/h2H2,1H3,(H,4,5)(H,6,7) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance 2-methylphosphinico-acetic acid [hydroxy(methyl)phosphoryl]acetic acid Not in list C3H7O4P O=C(O)CP(C)(=O)O InChI=1/C3H7O4P/c1-8(6,7)2-3(4)5/h2H2,1H3,(H,4,5)(H,6,7) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance 2-methylphosphinico-acetic acid [hydroxy(methyl)phosphoryl]acetic acid Not in list C3H7O4P O=C(O)CP(C)(=O)O InChI=1/C3H7O4P/c1-8(6,7)2-3(4)5/h2H2,1H3,(H,4,5)(H,6,7) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance 2-methylphosphinico-acetic acid [hydroxy(methyl)phosphoryl]acetic acid Not in list C3H7O4P O=C(O)CP(C)(=O)O InChI=1/C3H7O4P/c1-8(6,7)2-3(4)5/h2H2,1H3,(H,4,5)(H,6,7) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance 2-methylphosphinico-acetic acid [hydroxy(methyl)phosphoryl]acetic acid Not in list C3H7O4P O=C(O)CP(C)(=O)O InChI=1/C3H7O4P/c1-8(6,7)2-3(4)5/h2H2,1H3,(H,4,5)(H,6,7) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance 2-methylphosphinico-acetic acid [hydroxy(methyl)phosphoryl]acetic acid Not in list C3H7O4P O=C(O)CP(C)(=O)O InChI=1/C3H7O4P/c1-8(6,7)2-3(4)5/h2H2,1H3,(H,4,5)(H,6,7) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance 2-methylphosphinico-acetic acid [hydroxy(methyl)phosphoryl]acetic acid Not in list C3H7O4P O=C(O)CP(C)(=O)O InChI=1/C3H7O4P/c1-8(6,7)2-3(4)5/h2H2,1H3,(H,4,5)(H,6,7) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance 2-methylphosphinico-acetic acid [hydroxy(methyl)phosphoryl]acetic acid Not in list C3H7O4P O=C(O)CP(C)(=O)O InChI=1/C3H7O4P/c1-8(6,7)2-3(4)5/h2H2,1H3,(H,4,5)(H,6,7) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance 2-methylphosphinico-acetic acid [hydroxy(methyl)phosphoryl]acetic acid Not in list C3H7O4P O=C(O)CP(C)(=O)O InChI=1/C3H7O4P/c1-8(6,7)2-3(4)5/h2H2,1H3,(H,4,5)(H,6,7) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes with Positive RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance 2-methylphosphinico-acetic acid [hydroxy(methyl)phosphoryl]acetic acid Not in list C3H7O4P O=C(O)CP(C)(=O)O InChI=1/C3H7O4P/c1-8(6,7)2-3(4)5/h2H2,1H3,(H,4,5)(H,6,7) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes without Positive RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance 2-methylphosphinico-acetic acid [hydroxy(methyl)phosphoryl]acetic acid Not in list C3H7O4P O=C(O)CP(C)(=O)O InChI=1/C3H7O4P/c1-8(6,7)2-3(4)5/h2H2,1H3,(H,4,5)(H,6,7) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Glufosinate-ammonium 278-636-5 77182-82-2 single chemical entity Component is a metabolite of the substance 2-methylphosphinico-acetic acid [hydroxy(methyl)phosphoryl]acetic acid Not in list C3H7O4P O=C(O)CP(C)(=O)O InChI=1/C3H7O4P/c1-8(6,7)2-3(4)5/h2H2,1H3,(H,4,5)(H,6,7) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Sweden Glufosinate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate 30Mar2012 2012 doi:10.2903/j.efsa.2012.2609
+Halosulfuron-methyl 600-130-3 100784-20-1 single chemical entity Component is identical to the substance Halosulfuron-methyl 600-130-3 100784-20-1 methyl 3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-1-methylpyrazole-4-carboxylate Halosulfuron methyl C13H15ClN6O7S CN1C(=C(C(=N1)Cl)C(=O)OC)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C13H15ClN6O7S/c1-20-10(8(9(14)18-20)11(21)27-4)28(23,24)19-13(22)17-12-15-6(25-2)5-7(16-12)26-3/h5H,1-4H3,(H2,15,16,17,19,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Italy Halosulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl) 06Dec2012 2012 doi:10.2903/j.efsa.2012.2987
+Halosulfuron-methyl 600-130-3 100784-20-1 single chemical entity Component is identical to the substance Halosulfuron-methyl 600-130-3 100784-20-1 methyl 3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-1-methylpyrazole-4-carboxylate Halosulfuron methyl C13H15ClN6O7S CN1C(=C(C(=N1)Cl)C(=O)OC)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C13H15ClN6O7S/c1-20-10(8(9(14)18-20)11(21)27-4)28(23,24)19-13(22)17-12-15-6(25-2)5-7(16-12)26-3/h5H,1-4H3,(H2,15,16,17,19,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Italy Halosulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl) 06Dec2012 2012 doi:10.2903/j.efsa.2012.2987
+Halosulfuron-methyl 600-130-3 100784-20-1 single chemical entity Component is identical to the substance Halosulfuron-methyl 600-130-3 100784-20-1 methyl 3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-1-methylpyrazole-4-carboxylate Halosulfuron methyl C13H15ClN6O7S CN1C(=C(C(=N1)Cl)C(=O)OC)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C13H15ClN6O7S/c1-20-10(8(9(14)18-20)11(21)27-4)28(23,24)19-13(22)17-12-15-6(25-2)5-7(16-12)26-3/h5H,1-4H3,(H2,15,16,17,19,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Italy Halosulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl) 06Dec2012 2012 doi:10.2903/j.efsa.2012.2987
+Halosulfuron-methyl 600-130-3 100784-20-1 single chemical entity Component is identical to the substance Halosulfuron-methyl 600-130-3 100784-20-1 methyl 3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-1-methylpyrazole-4-carboxylate Halosulfuron methyl C13H15ClN6O7S CN1C(=C(C(=N1)Cl)C(=O)OC)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C13H15ClN6O7S/c1-20-10(8(9(14)18-20)11(21)27-4)28(23,24)19-13(22)17-12-15-6(25-2)5-7(16-12)26-3/h5H,1-4H3,(H2,15,16,17,19,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Italy Halosulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl) 06Dec2012 2012 doi:10.2903/j.efsa.2012.2987
+Halosulfuron-methyl 600-130-3 100784-20-1 single chemical entity Component is identical to the substance Halosulfuron-methyl 600-130-3 100784-20-1 methyl 3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-1-methylpyrazole-4-carboxylate Halosulfuron methyl C13H15ClN6O7S CN1C(=C(C(=N1)Cl)C(=O)OC)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C13H15ClN6O7S/c1-20-10(8(9(14)18-20)11(21)27-4)28(23,24)19-13(22)17-12-15-6(25-2)5-7(16-12)26-3/h5H,1-4H3,(H2,15,16,17,19,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Italy Halosulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl) 06Dec2012 2012 doi:10.2903/j.efsa.2012.2987
+Halosulfuron-methyl 600-130-3 100784-20-1 single chemical entity Component is identical to the substance Halosulfuron-methyl 600-130-3 100784-20-1 methyl 3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-1-methylpyrazole-4-carboxylate Halosulfuron methyl C13H15ClN6O7S CN1C(=C(C(=N1)Cl)C(=O)OC)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C13H15ClN6O7S/c1-20-10(8(9(14)18-20)11(21)27-4)28(23,24)19-13(22)17-12-15-6(25-2)5-7(16-12)26-3/h5H,1-4H3,(H2,15,16,17,19,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Italy Halosulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl) 06Dec2012 2012 doi:10.2903/j.efsa.2012.2987
+Halosulfuron-methyl 600-130-3 100784-20-1 single chemical entity Component is identical to the substance Halosulfuron-methyl 600-130-3 100784-20-1 methyl 3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-1-methylpyrazole-4-carboxylate Halosulfuron methyl C13H15ClN6O7S CN1C(=C(C(=N1)Cl)C(=O)OC)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C13H15ClN6O7S/c1-20-10(8(9(14)18-20)11(21)27-4)28(23,24)19-13(22)17-12-15-6(25-2)5-7(16-12)26-3/h5H,1-4H3,(H2,15,16,17,19,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Italy Halosulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl) 06Dec2012 2012 doi:10.2903/j.efsa.2012.2987
+Halosulfuron-methyl 600-130-3 100784-20-1 single chemical entity Component is identical to the substance Halosulfuron-methyl 600-130-3 100784-20-1 methyl 3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-1-methylpyrazole-4-carboxylate Halosulfuron methyl C13H15ClN6O7S CN1C(=C(C(=N1)Cl)C(=O)OC)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C13H15ClN6O7S/c1-20-10(8(9(14)18-20)11(21)27-4)28(23,24)19-13(22)17-12-15-6(25-2)5-7(16-12)26-3/h5H,1-4H3,(H2,15,16,17,19,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Italy Halosulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl) 06Dec2012 2012 doi:10.2903/j.efsa.2012.2987
+Halosulfuron-methyl 600-130-3 100784-20-1 single chemical entity Component is identical to the substance Halosulfuron-methyl 600-130-3 100784-20-1 methyl 3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-1-methylpyrazole-4-carboxylate Halosulfuron methyl C13H15ClN6O7S CN1C(=C(C(=N1)Cl)C(=O)OC)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C13H15ClN6O7S/c1-20-10(8(9(14)18-20)11(21)27-4)28(23,24)19-13(22)17-12-15-6(25-2)5-7(16-12)26-3/h5H,1-4H3,(H2,15,16,17,19,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Italy Halosulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl) 06Dec2012 2012 doi:10.2903/j.efsa.2012.2987
+Halosulfuron-methyl 600-130-3 100784-20-1 single chemical entity Component is identical to the substance Halosulfuron-methyl 600-130-3 100784-20-1 methyl 3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-1-methylpyrazole-4-carboxylate Halosulfuron methyl C13H15ClN6O7S CN1C(=C(C(=N1)Cl)C(=O)OC)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C13H15ClN6O7S/c1-20-10(8(9(14)18-20)11(21)27-4)28(23,24)19-13(22)17-12-15-6(25-2)5-7(16-12)26-3/h5H,1-4H3,(H2,15,16,17,19,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Italy Halosulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl) 06Dec2012 2012 doi:10.2903/j.efsa.2012.2987
+Halosulfuron-methyl 600-130-3 100784-20-1 single chemical entity Component is identical to the substance Halosulfuron-methyl 600-130-3 100784-20-1 methyl 3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-1-methylpyrazole-4-carboxylate Halosulfuron methyl C13H15ClN6O7S CN1C(=C(C(=N1)Cl)C(=O)OC)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C13H15ClN6O7S/c1-20-10(8(9(14)18-20)11(21)27-4)28(23,24)19-13(22)17-12-15-6(25-2)5-7(16-12)26-3/h5H,1-4H3,(H2,15,16,17,19,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Italy Halosulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl) 06Dec2012 2012 doi:10.2903/j.efsa.2012.2987
+Halosulfuron-methyl 600-130-3 100784-20-1 single chemical entity Component is identical to the substance Halosulfuron-methyl 600-130-3 100784-20-1 methyl 3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-1-methylpyrazole-4-carboxylate Halosulfuron methyl C13H15ClN6O7S CN1C(=C(C(=N1)Cl)C(=O)OC)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C13H15ClN6O7S/c1-20-10(8(9(14)18-20)11(21)27-4)28(23,24)19-13(22)17-12-15-6(25-2)5-7(16-12)26-3/h5H,1-4H3,(H2,15,16,17,19,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Italy Halosulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl) 06Dec2012 2012 doi:10.2903/j.efsa.2012.2987
+Halosulfuron-methyl 600-130-3 100784-20-1 single chemical entity Component is identical to the substance Halosulfuron-methyl 600-130-3 100784-20-1 methyl 3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-1-methylpyrazole-4-carboxylate Halosulfuron methyl C13H15ClN6O7S CN1C(=C(C(=N1)Cl)C(=O)OC)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C13H15ClN6O7S/c1-20-10(8(9(14)18-20)11(21)27-4)28(23,24)19-13(22)17-12-15-6(25-2)5-7(16-12)26-3/h5H,1-4H3,(H2,15,16,17,19,22) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Italy Halosulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl) 06Dec2012 2012 doi:10.2903/j.efsa.2012.2987
+Halosulfuron-methyl 600-130-3 100784-20-1 single chemical entity Component is identical to the substance Halosulfuron-methyl 600-130-3 100784-20-1 methyl 3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-1-methylpyrazole-4-carboxylate Halosulfuron methyl C13H15ClN6O7S CN1C(=C(C(=N1)Cl)C(=O)OC)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C13H15ClN6O7S/c1-20-10(8(9(14)18-20)11(21)27-4)28(23,24)19-13(22)17-12-15-6(25-2)5-7(16-12)26-3/h5H,1-4H3,(H2,15,16,17,19,22) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Italy Halosulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl) 06Dec2012 2012 doi:10.2903/j.efsa.2012.2987
+Halosulfuron-methyl 600-130-3 100784-20-1 single chemical entity Component is identical to the substance Halosulfuron-methyl 600-130-3 100784-20-1 methyl 3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-1-methylpyrazole-4-carboxylate Halosulfuron methyl C13H15ClN6O7S CN1C(=C(C(=N1)Cl)C(=O)OC)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C13H15ClN6O7S/c1-20-10(8(9(14)18-20)11(21)27-4)28(23,24)19-13(22)17-12-15-6(25-2)5-7(16-12)26-3/h5H,1-4H3,(H2,15,16,17,19,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Italy Halosulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl) 06Dec2012 2012 doi:10.2903/j.efsa.2012.2987
+Halosulfuron-methyl 600-130-3 100784-20-1 single chemical entity Component is identical to the substance Halosulfuron-methyl 600-130-3 100784-20-1 methyl 3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-1-methylpyrazole-4-carboxylate Halosulfuron methyl C13H15ClN6O7S CN1C(=C(C(=N1)Cl)C(=O)OC)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C13H15ClN6O7S/c1-20-10(8(9(14)18-20)11(21)27-4)28(23,24)19-13(22)17-12-15-6(25-2)5-7(16-12)26-3/h5H,1-4H3,(H2,15,16,17,19,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Italy Halosulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl) 06Dec2012 2012 doi:10.2903/j.efsa.2012.2987
+Halosulfuron-methyl 600-130-3 100784-20-1 single chemical entity Component is identical to the substance Halosulfuron-methyl 600-130-3 100784-20-1 methyl 3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-1-methylpyrazole-4-carboxylate Halosulfuron methyl C13H15ClN6O7S CN1C(=C(C(=N1)Cl)C(=O)OC)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C13H15ClN6O7S/c1-20-10(8(9(14)18-20)11(21)27-4)28(23,24)19-13(22)17-12-15-6(25-2)5-7(16-12)26-3/h5H,1-4H3,(H2,15,16,17,19,22) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) ICR 10 Male/Female oral: gavage 72.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Italy Halosulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl) 06Dec2012 2012 doi:10.2903/j.efsa.2012.2987
+Halosulfuron-methyl 600-130-3 100784-20-1 single chemical entity Component is identical to the substance Halosulfuron-methyl 600-130-3 100784-20-1 methyl 3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-1-methylpyrazole-4-carboxylate Halosulfuron methyl C13H15ClN6O7S CN1C(=C(C(=N1)Cl)C(=O)OC)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C13H15ClN6O7S/c1-20-10(8(9(14)18-20)11(21)27-4)28(23,24)19-13(22)17-12-15-6(25-2)5-7(16-12)26-3/h5H,1-4H3,(H2,15,16,17,19,22) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) ICR 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Italy Halosulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl) 06Dec2012 2012 doi:10.2903/j.efsa.2012.2987
+Halosulfuron-methyl 600-130-3 100784-20-1 single chemical entity Component is identical to the substance Halosulfuron-methyl 600-130-3 100784-20-1 methyl 3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-1-methylpyrazole-4-carboxylate Halosulfuron methyl C13H15ClN6O7S CN1C(=C(C(=N1)Cl)C(=O)OC)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C13H15ClN6O7S/c1-20-10(8(9(14)18-20)11(21)27-4)28(23,24)19-13(22)17-12-15-6(25-2)5-7(16-12)26-3/h5H,1-4H3,(H2,15,16,17,19,22) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) ICR 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Italy Halosulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl) 06Dec2012 2012 doi:10.2903/j.efsa.2012.2987
+Halosulfuron-methyl 600-130-3 100784-20-1 single chemical entity Component is identical to the substance Halosulfuron-methyl 600-130-3 100784-20-1 methyl 3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-1-methylpyrazole-4-carboxylate Halosulfuron methyl C13H15ClN6O7S CN1C(=C(C(=N1)Cl)C(=O)OC)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C13H15ClN6O7S/c1-20-10(8(9(14)18-20)11(21)27-4)28(23,24)19-13(22)17-12-15-6(25-2)5-7(16-12)26-3/h5H,1-4H3,(H2,15,16,17,19,22) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle with Negative RMS: Italy Halosulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl) 06Dec2012 2012 doi:10.2903/j.efsa.2012.2987
+Halosulfuron-methyl 600-130-3 100784-20-1 single chemical entity Component is a metabolite of the substance 3-chloro-1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylic acid 3-chloro-1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylic acid Not in list C5H6ClN3O4S OC(=O)c1c(n(C)nc1Cl)S(N)(=O)=O InChI=1/C5H6ClN3O4S/c1-9-4(14(7,12)13)2(5(10)11)3(6)8-9/h1H3,(H,10,11)(H2,7,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Italy Halosulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl) 06Dec2012 2012 doi:10.2903/j.efsa.2012.2987
+Halosulfuron-methyl 600-130-3 100784-20-1 single chemical entity Component is a metabolite of the substance 3-chloro-1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylic acid 3-chloro-1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylic acid Not in list C5H6ClN3O4S OC(=O)c1c(n(C)nc1Cl)S(N)(=O)=O InChI=1/C5H6ClN3O4S/c1-9-4(14(7,12)13)2(5(10)11)3(6)8-9/h1H3,(H,10,11)(H2,7,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Italy Halosulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl) 06Dec2012 2012 doi:10.2903/j.efsa.2012.2987
+Halosulfuron-methyl 600-130-3 100784-20-1 single chemical entity Component is a metabolite of the substance 3-chloro-1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylic acid 3-chloro-1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylic acid Not in list C5H6ClN3O4S OC(=O)c1c(n(C)nc1Cl)S(N)(=O)=O InChI=1/C5H6ClN3O4S/c1-9-4(14(7,12)13)2(5(10)11)3(6)8-9/h1H3,(H,10,11)(H2,7,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Italy Halosulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl) 06Dec2012 2012 doi:10.2903/j.efsa.2012.2987
+Halosulfuron-methyl 600-130-3 100784-20-1 single chemical entity Component is a metabolite of the substance 3-chloro-1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylic acid 3-chloro-1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylic acid Not in list C5H6ClN3O4S OC(=O)c1c(n(C)nc1Cl)S(N)(=O)=O InChI=1/C5H6ClN3O4S/c1-9-4(14(7,12)13)2(5(10)11)3(6)8-9/h1H3,(H,10,11)(H2,7,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Italy Halosulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl) 06Dec2012 2012 doi:10.2903/j.efsa.2012.2987
+Halosulfuron-methyl 600-130-3 100784-20-1 single chemical entity Component is a metabolite of the substance 3-chloro-1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylic acid 3-chloro-1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylic acid Not in list C5H6ClN3O4S OC(=O)c1c(n(C)nc1Cl)S(N)(=O)=O InChI=1/C5H6ClN3O4S/c1-9-4(14(7,12)13)2(5(10)11)3(6)8-9/h1H3,(H,10,11)(H2,7,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Italy Halosulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl) 06Dec2012 2012 doi:10.2903/j.efsa.2012.2987
+Halosulfuron-methyl 600-130-3 100784-20-1 single chemical entity Component is a metabolite of the substance 3-chloro-1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylic acid 3-chloro-1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylic acid Not in list C5H6ClN3O4S OC(=O)c1c(n(C)nc1Cl)S(N)(=O)=O InChI=1/C5H6ClN3O4S/c1-9-4(14(7,12)13)2(5(10)11)3(6)8-9/h1H3,(H,10,11)(H2,7,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Italy Halosulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl) 06Dec2012 2012 doi:10.2903/j.efsa.2012.2987
+Halosulfuron-methyl 600-130-3 100784-20-1 single chemical entity Component is a metabolite of the substance 3-chloro-1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylic acid 3-chloro-1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylic acid Not in list C5H6ClN3O4S OC(=O)c1c(n(C)nc1Cl)S(N)(=O)=O InChI=1/C5H6ClN3O4S/c1-9-4(14(7,12)13)2(5(10)11)3(6)8-9/h1H3,(H,10,11)(H2,7,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Italy Halosulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl) 06Dec2012 2012 doi:10.2903/j.efsa.2012.2987
+Halosulfuron-methyl 600-130-3 100784-20-1 single chemical entity Component is a metabolite of the substance 3-chloro-1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylic acid 3-chloro-1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylic acid Not in list C5H6ClN3O4S OC(=O)c1c(n(C)nc1Cl)S(N)(=O)=O InChI=1/C5H6ClN3O4S/c1-9-4(14(7,12)13)2(5(10)11)3(6)8-9/h1H3,(H,10,11)(H2,7,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Italy Halosulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl) 06Dec2012 2012 doi:10.2903/j.efsa.2012.2987
+Halosulfuron-methyl 600-130-3 100784-20-1 single chemical entity Component is a metabolite of the substance 3-chloro-1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylic acid 3-chloro-1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylic acid Not in list C5H6ClN3O4S OC(=O)c1c(n(C)nc1Cl)S(N)(=O)=O InChI=1/C5H6ClN3O4S/c1-9-4(14(7,12)13)2(5(10)11)3(6)8-9/h1H3,(H,10,11)(H2,7,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Italy Halosulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl) 06Dec2012 2012 doi:10.2903/j.efsa.2012.2987
+Halosulfuron-methyl 600-130-3 100784-20-1 single chemical entity Component is a metabolite of the substance 3-chloro-1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylic acid 3-chloro-1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylic acid Not in list C5H6ClN3O4S OC(=O)c1c(n(C)nc1Cl)S(N)(=O)=O InChI=1/C5H6ClN3O4S/c1-9-4(14(7,12)13)2(5(10)11)3(6)8-9/h1H3,(H,10,11)(H2,7,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Italy Halosulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl) 06Dec2012 2012 doi:10.2903/j.efsa.2012.2987
+Halosulfuron-methyl 600-130-3 100784-20-1 single chemical entity Component is a metabolite of the substance 3-chloro-1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylic acid 3-chloro-1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylic acid Not in list C5H6ClN3O4S OC(=O)c1c(n(C)nc1Cl)S(N)(=O)=O InChI=1/C5H6ClN3O4S/c1-9-4(14(7,12)13)2(5(10)11)3(6)8-9/h1H3,(H,10,11)(H2,7,12,13) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Italy Halosulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl) 06Dec2012 2012 doi:10.2903/j.efsa.2012.2987
+Halosulfuron-methyl 600-130-3 100784-20-1 single chemical entity Component is a metabolite of the substance 3-chloro-1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylic acid 3-chloro-1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylic acid Not in list C5H6ClN3O4S OC(=O)c1c(n(C)nc1Cl)S(N)(=O)=O InChI=1/C5H6ClN3O4S/c1-9-4(14(7,12)13)2(5(10)11)3(6)8-9/h1H3,(H,10,11)(H2,7,12,13) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Ambiguous RMS: Italy Halosulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl) 06Dec2012 2012 doi:10.2903/j.efsa.2012.2987
+Halosulfuron-methyl 600-130-3 100784-20-1 single chemical entity Component is a metabolite of the substance 3-chloro-1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylic acid 3-chloro-1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylic acid Not in list C5H6ClN3O4S OC(=O)c1c(n(C)nc1Cl)S(N)(=O)=O InChI=1/C5H6ClN3O4S/c1-9-4(14(7,12)13)2(5(10)11)3(6)8-9/h1H3,(H,10,11)(H2,7,12,13) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 72.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Italy Halosulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl) 06Dec2012 2012 doi:10.2903/j.efsa.2012.2987
+Halosulfuron-methyl 600-130-3 100784-20-1 single chemical entity Component is a metabolite of the substance 3-chloro-1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylic acid 3-chloro-1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylic acid Not in list C5H6ClN3O4S OC(=O)c1c(n(C)nc1Cl)S(N)(=O)=O InChI=1/C5H6ClN3O4S/c1-9-4(14(7,12)13)2(5(10)11)3(6)8-9/h1H3,(H,10,11)(H2,7,12,13) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Italy Halosulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl) 06Dec2012 2012 doi:10.2903/j.efsa.2012.2987
+Halosulfuron-methyl 600-130-3 100784-20-1 single chemical entity Component is a metabolite of the substance 3-chloro-1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylic acid 3-chloro-1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylic acid Not in list C5H6ClN3O4S OC(=O)c1c(n(C)nc1Cl)S(N)(=O)=O InChI=1/C5H6ClN3O4S/c1-9-4(14(7,12)13)2(5(10)11)3(6)8-9/h1H3,(H,10,11)(H2,7,12,13) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Italy Halosulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl) 06Dec2012 2012 doi:10.2903/j.efsa.2012.2987
+Halosulfuron-methyl 600-130-3 100784-20-1 single chemical entity Component is a metabolite of the substance methyl 3-chloro-5-[(4,6-dimethoxy-2-pyrimidinyl)amino]-1-methyl-1H-pyrazole-4-carboxylate 3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)methyl]-1-methyl-1H-pyrazole-4-carboxylic acid Not in list C12H13lN4O4 OC(=O)c2c(Cc1nc(OC)cc(OC)n1)n(C)nc2Cl InChI=1/C12H13ClN4O4/c1-17-6(10(12(18)19)11(13)16-17)4-7-14-8(20-2)5-9(15-7)21-3/h5H,4H2,1-3H3,(H,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Italy Halosulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl) 06Dec2012 2012 doi:10.2903/j.efsa.2012.2987
+Halosulfuron-methyl 600-130-3 100784-20-1 single chemical entity Component is a metabolite of the substance methyl 3-chloro-5-[(4,6-dimethoxy-2-pyrimidinyl)amino]-1-methyl-1H-pyrazole-4-carboxylate 3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)methyl]-1-methyl-1H-pyrazole-4-carboxylic acid Not in list C12H13lN4O4 OC(=O)c2c(Cc1nc(OC)cc(OC)n1)n(C)nc2Cl InChI=1/C12H13ClN4O4/c1-17-6(10(12(18)19)11(13)16-17)4-7-14-8(20-2)5-9(15-7)21-3/h5H,4H2,1-3H3,(H,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Italy Halosulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl) 06Dec2012 2012 doi:10.2903/j.efsa.2012.2987
+Halosulfuron-methyl 600-130-3 100784-20-1 single chemical entity Component is a metabolite of the substance methyl 3-chloro-5-[(4,6-dimethoxy-2-pyrimidinyl)amino]-1-methyl-1H-pyrazole-4-carboxylate 3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)methyl]-1-methyl-1H-pyrazole-4-carboxylic acid Not in list C12H13lN4O4 OC(=O)c2c(Cc1nc(OC)cc(OC)n1)n(C)nc2Cl InChI=1/C12H13ClN4O4/c1-17-6(10(12(18)19)11(13)16-17)4-7-14-8(20-2)5-9(15-7)21-3/h5H,4H2,1-3H3,(H,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Italy Halosulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl) 06Dec2012 2012 doi:10.2903/j.efsa.2012.2987
+Halosulfuron-methyl 600-130-3 100784-20-1 single chemical entity Component is a metabolite of the substance methyl 3-chloro-5-[(4,6-dimethoxy-2-pyrimidinyl)amino]-1-methyl-1H-pyrazole-4-carboxylate 3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)methyl]-1-methyl-1H-pyrazole-4-carboxylic acid Not in list C12H13lN4O4 OC(=O)c2c(Cc1nc(OC)cc(OC)n1)n(C)nc2Cl InChI=1/C12H13ClN4O4/c1-17-6(10(12(18)19)11(13)16-17)4-7-14-8(20-2)5-9(15-7)21-3/h5H,4H2,1-3H3,(H,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Italy Halosulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl) 06Dec2012 2012 doi:10.2903/j.efsa.2012.2987
+Halosulfuron-methyl 600-130-3 100784-20-1 single chemical entity Component is a metabolite of the substance methyl 3-chloro-5-[(4,6-dimethoxy-2-pyrimidinyl)amino]-1-methyl-1H-pyrazole-4-carboxylate 3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)methyl]-1-methyl-1H-pyrazole-4-carboxylic acid Not in list C12H13lN4O4 OC(=O)c2c(Cc1nc(OC)cc(OC)n1)n(C)nc2Cl InChI=1/C12H13ClN4O4/c1-17-6(10(12(18)19)11(13)16-17)4-7-14-8(20-2)5-9(15-7)21-3/h5H,4H2,1-3H3,(H,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Italy Halosulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl) 06Dec2012 2012 doi:10.2903/j.efsa.2012.2987
+Halosulfuron-methyl 600-130-3 100784-20-1 single chemical entity Component is a metabolite of the substance methyl 3-chloro-5-[(4,6-dimethoxy-2-pyrimidinyl)amino]-1-methyl-1H-pyrazole-4-carboxylate 3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)methyl]-1-methyl-1H-pyrazole-4-carboxylic acid Not in list C12H13lN4O4 OC(=O)c2c(Cc1nc(OC)cc(OC)n1)n(C)nc2Cl InChI=1/C12H13ClN4O4/c1-17-6(10(12(18)19)11(13)16-17)4-7-14-8(20-2)5-9(15-7)21-3/h5H,4H2,1-3H3,(H,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Italy Halosulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl) 06Dec2012 2012 doi:10.2903/j.efsa.2012.2987
+Halosulfuron-methyl 600-130-3 100784-20-1 single chemical entity Component is a metabolite of the substance methyl 3-chloro-5-[(4,6-dimethoxy-2-pyrimidinyl)amino]-1-methyl-1H-pyrazole-4-carboxylate 3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)methyl]-1-methyl-1H-pyrazole-4-carboxylic acid Not in list C12H13lN4O4 OC(=O)c2c(Cc1nc(OC)cc(OC)n1)n(C)nc2Cl InChI=1/C12H13ClN4O4/c1-17-6(10(12(18)19)11(13)16-17)4-7-14-8(20-2)5-9(15-7)21-3/h5H,4H2,1-3H3,(H,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Italy Halosulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl) 06Dec2012 2012 doi:10.2903/j.efsa.2012.2987
+Halosulfuron-methyl 600-130-3 100784-20-1 single chemical entity Component is a metabolite of the substance methyl 3-chloro-5-[(4,6-dimethoxy-2-pyrimidinyl)amino]-1-methyl-1H-pyrazole-4-carboxylate 3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)methyl]-1-methyl-1H-pyrazole-4-carboxylic acid Not in list C12H13lN4O4 OC(=O)c2c(Cc1nc(OC)cc(OC)n1)n(C)nc2Cl InChI=1/C12H13ClN4O4/c1-17-6(10(12(18)19)11(13)16-17)4-7-14-8(20-2)5-9(15-7)21-3/h5H,4H2,1-3H3,(H,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Italy Halosulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl) 06Dec2012 2012 doi:10.2903/j.efsa.2012.2987
+Halosulfuron-methyl 600-130-3 100784-20-1 single chemical entity Component is a metabolite of the substance methyl 3-chloro-5-[(4,6-dimethoxy-2-pyrimidinyl)amino]-1-methyl-1H-pyrazole-4-carboxylate 3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)methyl]-1-methyl-1H-pyrazole-4-carboxylic acid Not in list C12H13lN4O4 OC(=O)c2c(Cc1nc(OC)cc(OC)n1)n(C)nc2Cl InChI=1/C12H13ClN4O4/c1-17-6(10(12(18)19)11(13)16-17)4-7-14-8(20-2)5-9(15-7)21-3/h5H,4H2,1-3H3,(H,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Italy Halosulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl) 06Dec2012 2012 doi:10.2903/j.efsa.2012.2987
+Halosulfuron-methyl 600-130-3 100784-20-1 single chemical entity Component is a metabolite of the substance methyl 3-chloro-5-[(4,6-dimethoxy-2-pyrimidinyl)amino]-1-methyl-1H-pyrazole-4-carboxylate 3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)methyl]-1-methyl-1H-pyrazole-4-carboxylic acid Not in list C12H13lN4O4 OC(=O)c2c(Cc1nc(OC)cc(OC)n1)n(C)nc2Cl InChI=1/C12H13ClN4O4/c1-17-6(10(12(18)19)11(13)16-17)4-7-14-8(20-2)5-9(15-7)21-3/h5H,4H2,1-3H3,(H,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Italy Halosulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl) 06Dec2012 2012 doi:10.2903/j.efsa.2012.2987
+Halosulfuron-methyl 600-130-3 100784-20-1 single chemical entity Component is a metabolite of the substance methyl 3-chloro-5-[(4,6-dimethoxy-2-pyrimidinyl)amino]-1-methyl-1H-pyrazole-4-carboxylate 3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)methyl]-1-methyl-1H-pyrazole-4-carboxylic acid Not in list C12H13lN4O4 OC(=O)c2c(Cc1nc(OC)cc(OC)n1)n(C)nc2Cl InChI=1/C12H13ClN4O4/c1-17-6(10(12(18)19)11(13)16-17)4-7-14-8(20-2)5-9(15-7)21-3/h5H,4H2,1-3H3,(H,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Italy Halosulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl) 06Dec2012 2012 doi:10.2903/j.efsa.2012.2987
+Halosulfuron-methyl 600-130-3 100784-20-1 single chemical entity Component is a metabolite of the substance methyl 3-chloro-5-[(4,6-dimethoxy-2-pyrimidinyl)amino]-1-methyl-1H-pyrazole-4-carboxylate 3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)methyl]-1-methyl-1H-pyrazole-4-carboxylic acid Not in list C12H13lN4O4 OC(=O)c2c(Cc1nc(OC)cc(OC)n1)n(C)nc2Cl InChI=1/C12H13ClN4O4/c1-17-6(10(12(18)19)11(13)16-17)4-7-14-8(20-2)5-9(15-7)21-3/h5H,4H2,1-3H3,(H,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Italy Halosulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl) 06Dec2012 2012 doi:10.2903/j.efsa.2012.2987
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is identical to the substance Tetraconazole 407-760-6 112281-77-3 1-[2-(2,4-Dichlorophenyl)-3-(1,1,2,2-tetrafluoroethoxy)propyl]-1,2, 4-triazole Tetraconazole C13H11Cl2F4N3O C1=CC(=C(C=C1Cl)Cl)C(CN2C=NC=N2)COC(C(F)F)(F)F InChI=1S/C13H11Cl2F4N3O/c14-9-1-2-10(11(15)3-9)8(4-22-7-20-6-21-22)5-23-13(18,19)12(16)17/h1-3,6-8,12H,4-5H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is identical to the substance Tetraconazole 407-760-6 112281-77-3 1-[2-(2,4-Dichlorophenyl)-3-(1,1,2,2-tetrafluoroethoxy)propyl]-1,2, 4-triazole Tetraconazole C13H11Cl2F4N3O C1=CC(=C(C=C1Cl)Cl)C(CN2C=NC=N2)COC(C(F)F)(F)F InChI=1S/C13H11Cl2F4N3O/c14-9-1-2-10(11(15)3-9)8(4-22-7-20-6-21-22)5-23-13(18,19)12(16)17/h1-3,6-8,12H,4-5H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is identical to the substance Tetraconazole 407-760-6 112281-77-3 1-[2-(2,4-Dichlorophenyl)-3-(1,1,2,2-tetrafluoroethoxy)propyl]-1,2, 4-triazole Tetraconazole C13H11Cl2F4N3O C1=CC(=C(C=C1Cl)Cl)C(CN2C=NC=N2)COC(C(F)F)(F)F InChI=1S/C13H11Cl2F4N3O/c14-9-1-2-10(11(15)3-9)8(4-22-7-20-6-21-22)5-23-13(18,19)12(16)17/h1-3,6-8,12H,4-5H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is identical to the substance Tetraconazole 407-760-6 112281-77-3 1-[2-(2,4-Dichlorophenyl)-3-(1,1,2,2-tetrafluoroethoxy)propyl]-1,2, 4-triazole Tetraconazole C13H11Cl2F4N3O C1=CC(=C(C=C1Cl)Cl)C(CN2C=NC=N2)COC(C(F)F)(F)F InChI=1S/C13H11Cl2F4N3O/c14-9-1-2-10(11(15)3-9)8(4-22-7-20-6-21-22)5-23-13(18,19)12(16)17/h1-3,6-8,12H,4-5H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is identical to the substance Tetraconazole 407-760-6 112281-77-3 1-[2-(2,4-Dichlorophenyl)-3-(1,1,2,2-tetrafluoroethoxy)propyl]-1,2, 4-triazole Tetraconazole C13H11Cl2F4N3O C1=CC(=C(C=C1Cl)Cl)C(CN2C=NC=N2)COC(C(F)F)(F)F InChI=1S/C13H11Cl2F4N3O/c14-9-1-2-10(11(15)3-9)8(4-22-7-20-6-21-22)5-23-13(18,19)12(16)17/h1-3,6-8,12H,4-5H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is identical to the substance Tetraconazole 407-760-6 112281-77-3 1-[2-(2,4-Dichlorophenyl)-3-(1,1,2,2-tetrafluoroethoxy)propyl]-1,2, 4-triazole Tetraconazole C13H11Cl2F4N3O C1=CC(=C(C=C1Cl)Cl)C(CN2C=NC=N2)COC(C(F)F)(F)F InChI=1S/C13H11Cl2F4N3O/c14-9-1-2-10(11(15)3-9)8(4-22-7-20-6-21-22)5-23-13(18,19)12(16)17/h1-3,6-8,12H,4-5H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is identical to the substance Tetraconazole 407-760-6 112281-77-3 1-[2-(2,4-Dichlorophenyl)-3-(1,1,2,2-tetrafluoroethoxy)propyl]-1,2, 4-triazole Tetraconazole C13H11Cl2F4N3O C1=CC(=C(C=C1Cl)Cl)C(CN2C=NC=N2)COC(C(F)F)(F)F InChI=1S/C13H11Cl2F4N3O/c14-9-1-2-10(11(15)3-9)8(4-22-7-20-6-21-22)5-23-13(18,19)12(16)17/h1-3,6-8,12H,4-5H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is identical to the substance Tetraconazole 407-760-6 112281-77-3 1-[2-(2,4-Dichlorophenyl)-3-(1,1,2,2-tetrafluoroethoxy)propyl]-1,2, 4-triazole Tetraconazole C13H11Cl2F4N3O C1=CC(=C(C=C1Cl)Cl)C(CN2C=NC=N2)COC(C(F)F)(F)F InChI=1S/C13H11Cl2F4N3O/c14-9-1-2-10(11(15)3-9)8(4-22-7-20-6-21-22)5-23-13(18,19)12(16)17/h1-3,6-8,12H,4-5H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is identical to the substance Tetraconazole 407-760-6 112281-77-3 1-[2-(2,4-Dichlorophenyl)-3-(1,1,2,2-tetrafluoroethoxy)propyl]-1,2, 4-triazole Tetraconazole C13H11Cl2F4N3O C1=CC(=C(C=C1Cl)Cl)C(CN2C=NC=N2)COC(C(F)F)(F)F InChI=1S/C13H11Cl2F4N3O/c14-9-1-2-10(11(15)3-9)8(4-22-7-20-6-21-22)5-23-13(18,19)12(16)17/h1-3,6-8,12H,4-5H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is identical to the substance Tetraconazole 407-760-6 112281-77-3 1-[2-(2,4-Dichlorophenyl)-3-(1,1,2,2-tetrafluoroethoxy)propyl]-1,2, 4-triazole Tetraconazole C13H11Cl2F4N3O C1=CC(=C(C=C1Cl)Cl)C(CN2C=NC=N2)COC(C(F)F)(F)F InChI=1S/C13H11Cl2F4N3O/c14-9-1-2-10(11(15)3-9)8(4-22-7-20-6-21-22)5-23-13(18,19)12(16)17/h1-3,6-8,12H,4-5H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is identical to the substance Tetraconazole 407-760-6 112281-77-3 1-[2-(2,4-Dichlorophenyl)-3-(1,1,2,2-tetrafluoroethoxy)propyl]-1,2, 4-triazole Tetraconazole C13H11Cl2F4N3O C1=CC(=C(C=C1Cl)Cl)C(CN2C=NC=N2)COC(C(F)F)(F)F InChI=1S/C13H11Cl2F4N3O/c14-9-1-2-10(11(15)3-9)8(4-22-7-20-6-21-22)5-23-13(18,19)12(16)17/h1-3,6-8,12H,4-5H2 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is identical to the substance Tetraconazole 407-760-6 112281-77-3 1-[2-(2,4-Dichlorophenyl)-3-(1,1,2,2-tetrafluoroethoxy)propyl]-1,2, 4-triazole Tetraconazole C13H11Cl2F4N3O C1=CC(=C(C=C1Cl)Cl)C(CN2C=NC=N2)COC(C(F)F)(F)F InChI=1S/C13H11Cl2F4N3O/c14-9-1-2-10(11(15)3-9)8(4-22-7-20-6-21-22)5-23-13(18,19)12(16)17/h1-3,6-8,12H,4-5H2 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is identical to the substance Tetraconazole 407-760-6 112281-77-3 1-[2-(2,4-Dichlorophenyl)-3-(1,1,2,2-tetrafluoroethoxy)propyl]-1,2, 4-triazole Tetraconazole C13H11Cl2F4N3O C1=CC(=C(C=C1Cl)Cl)C(CN2C=NC=N2)COC(C(F)F)(F)F InChI=1S/C13H11Cl2F4N3O/c14-9-1-2-10(11(15)3-9)8(4-22-7-20-6-21-22)5-23-13(18,19)12(16)17/h1-3,6-8,12H,4-5H2 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Human (as organism) HeLa cells Not reported yes, concurrent vehicle without Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is identical to the substance Tetraconazole 407-760-6 112281-77-3 1-[2-(2,4-Dichlorophenyl)-3-(1,1,2,2-tetrafluoroethoxy)propyl]-1,2, 4-triazole Tetraconazole C13H11Cl2F4N3O C1=CC(=C(C=C1Cl)Cl)C(CN2C=NC=N2)COC(C(F)F)(F)F InChI=1S/C13H11Cl2F4N3O/c14-9-1-2-10(11(15)3-9)8(4-22-7-20-6-21-22)5-23-13(18,19)12(16)17/h1-3,6-8,12H,4-5H2 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Human (as organism) HeLa cells Not reported yes, concurrent vehicle with Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is identical to the substance Tetraconazole 407-760-6 112281-77-3 1-[2-(2,4-Dichlorophenyl)-3-(1,1,2,2-tetrafluoroethoxy)propyl]-1,2, 4-triazole Tetraconazole C13H11Cl2F4N3O C1=CC(=C(C=C1Cl)Cl)C(CN2C=NC=N2)COC(C(F)F)(F)F InChI=1S/C13H11Cl2F4N3O/c14-9-1-2-10(11(15)3-9)8(4-22-7-20-6-21-22)5-23-13(18,19)12(16)17/h1-3,6-8,12H,4-5H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is identical to the substance Tetraconazole 407-760-6 112281-77-3 1-[2-(2,4-Dichlorophenyl)-3-(1,1,2,2-tetrafluoroethoxy)propyl]-1,2, 4-triazole Tetraconazole C13H11Cl2F4N3O C1=CC(=C(C=C1Cl)Cl)C(CN2C=NC=N2)COC(C(F)F)(F)F InChI=1S/C13H11Cl2F4N3O/c14-9-1-2-10(11(15)3-9)8(4-22-7-20-6-21-22)5-23-13(18,19)12(16)17/h1-3,6-8,12H,4-5H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is identical to the substance Tetraconazole 407-760-6 112281-77-3 1-[2-(2,4-Dichlorophenyl)-3-(1,1,2,2-tetrafluoroethoxy)propyl]-1,2, 4-triazole Tetraconazole C13H11Cl2F4N3O C1=CC(=C(C=C1Cl)Cl)C(CN2C=NC=N2)COC(C(F)F)(F)F InChI=1S/C13H11Cl2F4N3O/c14-9-1-2-10(11(15)3-9)8(4-22-7-20-6-21-22)5-23-13(18,19)12(16)17/h1-3,6-8,12H,4-5H2 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is identical to the substance Tetraconazole 407-760-6 112281-77-3 1-[2-(2,4-Dichlorophenyl)-3-(1,1,2,2-tetrafluoroethoxy)propyl]-1,2, 4-triazole Tetraconazole C13H11Cl2F4N3O C1=CC(=C(C=C1Cl)Cl)C(CN2C=NC=N2)COC(C(F)F)(F)F InChI=1S/C13H11Cl2F4N3O/c14-9-1-2-10(11(15)3-9)8(4-22-7-20-6-21-22)5-23-13(18,19)12(16)17/h1-3,6-8,12H,4-5H2 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is identical to the substance Tetraconazole 407-760-6 112281-77-3 1-[2-(2,4-Dichlorophenyl)-3-(1,1,2,2-tetrafluoroethoxy)propyl]-1,2, 4-triazole Tetraconazole C13H11Cl2F4N3O C1=CC(=C(C=C1Cl)Cl)C(CN2C=NC=N2)COC(C(F)F)(F)F InChI=1S/C13H11Cl2F4N3O/c14-9-1-2-10(11(15)3-9)8(4-22-7-20-6-21-22)5-23-13(18,19)12(16)17/h1-3,6-8,12H,4-5H2 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 72.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance 2-(2,4-Dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propanoic acid 2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propanoic acid Not in list C11H9Cl2N3O2 OC(=O)C(Cn1cncn1)c2ccc(Cl)cc2Cl InChI=1S/C11H9Cl2N3O2/c12-7-1-2-8(10(13)3-7)9(11(17)18)4-16-6-14-5-15-16/h1-3,5-6,9H,4H2,(H,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance 2-(2,4-Dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propanoic acid 2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propanoic acid Not in list C11H9Cl2N3O2 OC(=O)C(Cn1cncn1)c2ccc(Cl)cc2Cl InChI=1S/C11H9Cl2N3O2/c12-7-1-2-8(10(13)3-7)9(11(17)18)4-16-6-14-5-15-16/h1-3,5-6,9H,4H2,(H,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance 2-(2,4-Dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propanoic acid 2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propanoic acid Not in list C11H9Cl2N3O2 OC(=O)C(Cn1cncn1)c2ccc(Cl)cc2Cl InChI=1S/C11H9Cl2N3O2/c12-7-1-2-8(10(13)3-7)9(11(17)18)4-16-6-14-5-15-16/h1-3,5-6,9H,4H2,(H,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance 2-(2,4-Dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propanoic acid 2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propanoic acid Not in list C11H9Cl2N3O2 OC(=O)C(Cn1cncn1)c2ccc(Cl)cc2Cl InChI=1S/C11H9Cl2N3O2/c12-7-1-2-8(10(13)3-7)9(11(17)18)4-16-6-14-5-15-16/h1-3,5-6,9H,4H2,(H,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance 2-(2,4-Dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propanoic acid 2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propanoic acid Not in list C11H9Cl2N3O2 OC(=O)C(Cn1cncn1)c2ccc(Cl)cc2Cl InChI=1S/C11H9Cl2N3O2/c12-7-1-2-8(10(13)3-7)9(11(17)18)4-16-6-14-5-15-16/h1-3,5-6,9H,4H2,(H,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance 2-(2,4-Dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propanoic acid 2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propanoic acid Not in list C11H9Cl2N3O2 OC(=O)C(Cn1cncn1)c2ccc(Cl)cc2Cl InChI=1S/C11H9Cl2N3O2/c12-7-1-2-8(10(13)3-7)9(11(17)18)4-16-6-14-5-15-16/h1-3,5-6,9H,4H2,(H,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle with Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance 2-(2,4-Dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propanoic acid 2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propanoic acid Not in list C11H9Cl2N3O2 OC(=O)C(Cn1cncn1)c2ccc(Cl)cc2Cl InChI=1S/C11H9Cl2N3O2/c12-7-1-2-8(10(13)3-7)9(11(17)18)4-16-6-14-5-15-16/h1-3,5-6,9H,4H2,(H,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance 2-(2,4-Dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propanoic acid 2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propanoic acid Not in list C11H9Cl2N3O2 OC(=O)C(Cn1cncn1)c2ccc(Cl)cc2Cl InChI=1S/C11H9Cl2N3O2/c12-7-1-2-8(10(13)3-7)9(11(17)18)4-16-6-14-5-15-16/h1-3,5-6,9H,4H2,(H,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance 2-(2,4-Dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propanoic acid 2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propanoic acid Not in list C11H9Cl2N3O2 OC(=O)C(Cn1cncn1)c2ccc(Cl)cc2Cl InChI=1S/C11H9Cl2N3O2/c12-7-1-2-8(10(13)3-7)9(11(17)18)4-16-6-14-5-15-16/h1-3,5-6,9H,4H2,(H,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle without Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance 2-(2,4-Dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propanoic acid 2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propanoic acid Not in list C11H9Cl2N3O2 OC(=O)C(Cn1cncn1)c2ccc(Cl)cc2Cl InChI=1S/C11H9Cl2N3O2/c12-7-1-2-8(10(13)3-7)9(11(17)18)4-16-6-14-5-15-16/h1-3,5-6,9H,4H2,(H,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance 2-(2,4-Dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propanoic acid 2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propanoic acid Not in list C11H9Cl2N3O2 OC(=O)C(Cn1cncn1)c2ccc(Cl)cc2Cl InChI=1S/C11H9Cl2N3O2/c12-7-1-2-8(10(13)3-7)9(11(17)18)4-16-6-14-5-15-16/h1-3,5-6,9H,4H2,(H,17,18) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance 2-(2,4-Dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propanoic acid 2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propanoic acid Not in list C11H9Cl2N3O2 OC(=O)C(Cn1cncn1)c2ccc(Cl)cc2Cl InChI=1S/C11H9Cl2N3O2/c12-7-1-2-8(10(13)3-7)9(11(17)18)4-16-6-14-5-15-16/h1-3,5-6,9H,4H2,(H,17,18) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance 2-(2,4-Dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propanoic acid 2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propanoic acid Not in list C11H9Cl2N3O2 OC(=O)C(Cn1cncn1)c2ccc(Cl)cc2Cl InChI=1S/C11H9Cl2N3O2/c12-7-1-2-8(10(13)3-7)9(11(17)18)4-16-6-14-5-15-16/h1-3,5-6,9H,4H2,(H,17,18) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Positive RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance 2-(2,4-Dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propanoic acid 2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propanoic acid Not in list C11H9Cl2N3O2 OC(=O)C(Cn1cncn1)c2ccc(Cl)cc2Cl InChI=1S/C11H9Cl2N3O2/c12-7-1-2-8(10(13)3-7)9(11(17)18)4-16-6-14-5-15-16/h1-3,5-6,9H,4H2,(H,17,18) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Positive RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance 2-(2,4-Dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propanoic acid 2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propanoic acid Not in list C11H9Cl2N3O2 OC(=O)C(Cn1cncn1)c2ccc(Cl)cc2Cl InChI=1S/C11H9Cl2N3O2/c12-7-1-2-8(10(13)3-7)9(11(17)18)4-16-6-14-5-15-16/h1-3,5-6,9H,4H2,(H,17,18) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 7 Male intraperitoneal 48.0000000000 h yes not applicable Negative indirect evidence-systemic toxicity RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance 2-(2,4-Dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propanoic acid 2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propanoic acid Not in list C11H9Cl2N3O2 OC(=O)C(Cn1cncn1)c2ccc(Cl)cc2Cl InChI=1S/C11H9Cl2N3O2/c12-7-1-2-8(10(13)3-7)9(11(17)18)4-16-6-14-5-15-16/h1-3,5-6,9H,4H2,(H,17,18) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 7 Male intraperitoneal 24.0000000000 h yes not applicable Negative indirect evidence-systemic toxicity RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Negative no information RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative no information RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance [2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propoxy](difluoro)acetic acid [2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propoxy](difluoro)acetic acid Not in list C13H11Cl2F2N3O3 O=C(O)C(F)(F)OCC(Cn1cncn1)c2ccc(Cl)cc2Cl InChI=1/C13H11Cl2F2N3O3/c14-9-1-2-10(11(15)3-9)8(4-20-7-18-6-19-20)5-23-13(16,17)12(21)22/h1-3,6-8H,4-5H2,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance [2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propoxy](difluoro)acetic acid [2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propoxy](difluoro)acetic acid Not in list C13H11Cl2F2N3O3 O=C(O)C(F)(F)OCC(Cn1cncn1)c2ccc(Cl)cc2Cl InChI=1/C13H11Cl2F2N3O3/c14-9-1-2-10(11(15)3-9)8(4-20-7-18-6-19-20)5-23-13(16,17)12(21)22/h1-3,6-8H,4-5H2,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance [2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propoxy](difluoro)acetic acid [2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propoxy](difluoro)acetic acid Not in list C13H11Cl2F2N3O3 O=C(O)C(F)(F)OCC(Cn1cncn1)c2ccc(Cl)cc2Cl InChI=1/C13H11Cl2F2N3O3/c14-9-1-2-10(11(15)3-9)8(4-20-7-18-6-19-20)5-23-13(16,17)12(21)22/h1-3,6-8H,4-5H2,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance [2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propoxy](difluoro)acetic acid [2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propoxy](difluoro)acetic acid Not in list C13H11Cl2F2N3O3 O=C(O)C(F)(F)OCC(Cn1cncn1)c2ccc(Cl)cc2Cl InChI=1/C13H11Cl2F2N3O3/c14-9-1-2-10(11(15)3-9)8(4-20-7-18-6-19-20)5-23-13(16,17)12(21)22/h1-3,6-8H,4-5H2,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance [2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propoxy](difluoro)acetic acid [2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propoxy](difluoro)acetic acid Not in list C13H11Cl2F2N3O3 O=C(O)C(F)(F)OCC(Cn1cncn1)c2ccc(Cl)cc2Cl InChI=1/C13H11Cl2F2N3O3/c14-9-1-2-10(11(15)3-9)8(4-20-7-18-6-19-20)5-23-13(16,17)12(21)22/h1-3,6-8H,4-5H2,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance [2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propoxy](difluoro)acetic acid [2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propoxy](difluoro)acetic acid Not in list C13H11Cl2F2N3O3 O=C(O)C(F)(F)OCC(Cn1cncn1)c2ccc(Cl)cc2Cl InChI=1/C13H11Cl2F2N3O3/c14-9-1-2-10(11(15)3-9)8(4-20-7-18-6-19-20)5-23-13(16,17)12(21)22/h1-3,6-8H,4-5H2,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance [2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propoxy](difluoro)acetic acid [2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propoxy](difluoro)acetic acid Not in list C13H11Cl2F2N3O3 O=C(O)C(F)(F)OCC(Cn1cncn1)c2ccc(Cl)cc2Cl InChI=1/C13H11Cl2F2N3O3/c14-9-1-2-10(11(15)3-9)8(4-20-7-18-6-19-20)5-23-13(16,17)12(21)22/h1-3,6-8H,4-5H2,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance [2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propoxy](difluoro)acetic acid [2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propoxy](difluoro)acetic acid Not in list C13H11Cl2F2N3O3 O=C(O)C(F)(F)OCC(Cn1cncn1)c2ccc(Cl)cc2Cl InChI=1/C13H11Cl2F2N3O3/c14-9-1-2-10(11(15)3-9)8(4-20-7-18-6-19-20)5-23-13(16,17)12(21)22/h1-3,6-8H,4-5H2,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance [2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propoxy](difluoro)acetic acid [2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propoxy](difluoro)acetic acid Not in list C13H11Cl2F2N3O3 O=C(O)C(F)(F)OCC(Cn1cncn1)c2ccc(Cl)cc2Cl InChI=1/C13H11Cl2F2N3O3/c14-9-1-2-10(11(15)3-9)8(4-20-7-18-6-19-20)5-23-13(16,17)12(21)22/h1-3,6-8H,4-5H2,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance [2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propoxy](difluoro)acetic acid [2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propoxy](difluoro)acetic acid Not in list C13H11Cl2F2N3O3 O=C(O)C(F)(F)OCC(Cn1cncn1)c2ccc(Cl)cc2Cl InChI=1/C13H11Cl2F2N3O3/c14-9-1-2-10(11(15)3-9)8(4-20-7-18-6-19-20)5-23-13(16,17)12(21)22/h1-3,6-8H,4-5H2,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Fluopicolide 239110-15-7 single chemical entity Component is identical to the substance Fluopicolide 239110-15-7 2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide Fluopicolide C14H8Cl3F3N2O C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Positive RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is identical to the substance Fluopicolide 239110-15-7 2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide Fluopicolide C14H8Cl3F3N2O C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Positive RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is identical to the substance Fluopicolide 239110-15-7 2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide Fluopicolide C14H8Cl3F3N2O C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is identical to the substance Fluopicolide 239110-15-7 2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide Fluopicolide C14H8Cl3F3N2O C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is identical to the substance Fluopicolide 239110-15-7 2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide Fluopicolide C14H8Cl3F3N2O C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is identical to the substance Fluopicolide 239110-15-7 2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide Fluopicolide C14H8Cl3F3N2O C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is identical to the substance Fluopicolide 239110-15-7 2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide Fluopicolide C14H8Cl3F3N2O C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is identical to the substance Fluopicolide 239110-15-7 2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide Fluopicolide C14H8Cl3F3N2O C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is identical to the substance Fluopicolide 239110-15-7 2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide Fluopicolide C14H8Cl3F3N2O C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is identical to the substance Fluopicolide 239110-15-7 2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide Fluopicolide C14H8Cl3F3N2O C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Positive RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is identical to the substance Fluopicolide 239110-15-7 2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide Fluopicolide C14H8Cl3F3N2O C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is identical to the substance Fluopicolide 239110-15-7 2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide Fluopicolide C14H8Cl3F3N2O C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is identical to the substance Fluopicolide 239110-15-7 2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide Fluopicolide C14H8Cl3F3N2O C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is identical to the substance Fluopicolide 239110-15-7 2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide Fluopicolide C14H8Cl3F3N2O C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is identical to the substance Fluopicolide 239110-15-7 2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide Fluopicolide C14H8Cl3F3N2O C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is identical to the substance Fluopicolide 239110-15-7 2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide Fluopicolide C14H8Cl3F3N2O C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is identical to the substance Fluopicolide 239110-15-7 2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide Fluopicolide C14H8Cl3F3N2O C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is identical to the substance Fluopicolide 239110-15-7 2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide Fluopicolide C14H8Cl3F3N2O C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is identical to the substance Fluopicolide 239110-15-7 2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide Fluopicolide C14H8Cl3F3N2O C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is identical to the substance Fluopicolide 239110-15-7 2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide Fluopicolide C14H8Cl3F3N2O C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is identical to the substance Fluopicolide 239110-15-7 2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide Fluopicolide C14H8Cl3F3N2O C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is identical to the substance Fluopicolide 239110-15-7 2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide Fluopicolide C14H8Cl3F3N2O C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is identical to the substance Fluopicolide 239110-15-7 2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide Fluopicolide C14H8Cl3F3N2O C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is identical to the substance Fluopicolide 239110-15-7 2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide Fluopicolide C14H8Cl3F3N2O C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is identical to the substance Fluopicolide 239110-15-7 2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide Fluopicolide C14H8Cl3F3N2O C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is identical to the substance Fluopicolide 239110-15-7 2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide Fluopicolide C14H8Cl3F3N2O C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is identical to the substance Fluopicolide 239110-15-7 2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide Fluopicolide C14H8Cl3F3N2O C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is identical to the substance Fluopicolide 239110-15-7 2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide Fluopicolide C14H8Cl3F3N2O C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is identical to the substance Fluopicolide 239110-15-7 2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide Fluopicolide C14H8Cl3F3N2O C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is identical to the substance Fluopicolide 239110-15-7 2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide Fluopicolide C14H8Cl3F3N2O C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is identical to the substance Fluopicolide 239110-15-7 2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide Fluopicolide C14H8Cl3F3N2O C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is identical to the substance Fluopicolide 239110-15-7 2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide Fluopicolide C14H8Cl3F3N2O C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is identical to the substance Fluopicolide 239110-15-7 2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide Fluopicolide C14H8Cl3F3N2O C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is identical to the substance Fluopicolide 239110-15-7 2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide Fluopicolide C14H8Cl3F3N2O C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is identical to the substance Fluopicolide 239110-15-7 2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide Fluopicolide C14H8Cl3F3N2O C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is identical to the substance Fluopicolide 239110-15-7 2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide Fluopicolide C14H8Cl3F3N2O C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is identical to the substance Fluopicolide 239110-15-7 2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide Fluopicolide C14H8Cl3F3N2O C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is identical to the substance Fluopicolide 239110-15-7 2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide Fluopicolide C14H8Cl3F3N2O C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is identical to the substance Fluopicolide 239110-15-7 2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide Fluopicolide C14H8Cl3F3N2O C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is identical to the substance Fluopicolide 239110-15-7 2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide Fluopicolide C14H8Cl3F3N2O C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is identical to the substance Fluopicolide 239110-15-7 2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide Fluopicolide C14H8Cl3F3N2O C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is identical to the substance Fluopicolide 239110-15-7 2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide Fluopicolide C14H8Cl3F3N2O C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is identical to the substance Fluopicolide 239110-15-7 2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide Fluopicolide C14H8Cl3F3N2O C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is identical to the substance Fluopicolide 239110-15-7 2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide Fluopicolide C14H8Cl3F3N2O C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is identical to the substance Fluopicolide 239110-15-7 2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide Fluopicolide C14H8Cl3F3N2O C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is identical to the substance Fluopicolide 239110-15-7 2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide Fluopicolide C14H8Cl3F3N2O C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is identical to the substance Fluopicolide 239110-15-7 2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide Fluopicolide C14H8Cl3F3N2O C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is identical to the substance Fluopicolide 239110-15-7 2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide Fluopicolide C14H8Cl3F3N2O C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is identical to the substance Fluopicolide 239110-15-7 2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide Fluopicolide C14H8Cl3F3N2O C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is identical to the substance Fluopicolide 239110-15-7 2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide Fluopicolide C14H8Cl3F3N2O C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is identical to the substance Fluopicolide 239110-15-7 2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide Fluopicolide C14H8Cl3F3N2O C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Positive RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is identical to the substance Fluopicolide 239110-15-7 2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide Fluopicolide C14H8Cl3F3N2O C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Positive RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is identical to the substance Fluopicolide 239110-15-7 2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide Fluopicolide C14H8Cl3F3N2O C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is identical to the substance Fluopicolide 239110-15-7 2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide Fluopicolide C14H8Cl3F3N2O C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is identical to the substance Fluopicolide 239110-15-7 2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide Fluopicolide C14H8Cl3F3N2O C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is identical to the substance Fluopicolide 239110-15-7 2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide Fluopicolide C14H8Cl3F3N2O C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is identical to the substance Fluopicolide 239110-15-7 2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide Fluopicolide C14H8Cl3F3N2O C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 24.0000000000 h yes not applicable Negative no evidence RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is identical to the substance Fluopicolide 239110-15-7 2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide Fluopicolide C14H8Cl3F3N2O C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 6 Male oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is identical to the substance Fluopicolide 239110-15-7 2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide Fluopicolide C14H8Cl3F3N2O C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 5 Male intraperitoneal 24.0000000000 h yes not applicable Negative direct evidence-cytotoxicity$indirect evidence-systemic toxicity RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is identical to the substance Fluopicolide 239110-15-7 2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide Fluopicolide C14H8Cl3F3N2O C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Sprague-Dawley 4 Male oral: gavage 14.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is identical to the substance Fluopicolide 239110-15-7 2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide Fluopicolide C14H8Cl3F3N2O C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Sprague-Dawley 4 Male oral: gavage 2.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 2,6-Dichlorobenzamide 217-918-4 2008-58-4 2,6-dichlorobenzamide Not in list C7H5Cl2NO C1=CC(=C(C(=C1)Cl)C(=O)N)Cl InChI=1S/C7H5Cl2NO/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3H,(H2,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 2,6-Dichlorobenzamide 217-918-4 2008-58-4 2,6-dichlorobenzamide Not in list C7H5Cl2NO C1=CC(=C(C(=C1)Cl)C(=O)N)Cl InChI=1S/C7H5Cl2NO/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3H,(H2,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 2,6-Dichlorobenzamide 217-918-4 2008-58-4 2,6-dichlorobenzamide Not in list C7H5Cl2NO C1=CC(=C(C(=C1)Cl)C(=O)N)Cl InChI=1S/C7H5Cl2NO/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3H,(H2,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 2,6-Dichlorobenzamide 217-918-4 2008-58-4 2,6-dichlorobenzamide Not in list C7H5Cl2NO C1=CC(=C(C(=C1)Cl)C(=O)N)Cl InChI=1S/C7H5Cl2NO/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3H,(H2,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 2,6-Dichlorobenzamide 217-918-4 2008-58-4 2,6-dichlorobenzamide Not in list C7H5Cl2NO C1=CC(=C(C(=C1)Cl)C(=O)N)Cl InChI=1S/C7H5Cl2NO/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3H,(H2,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 2,6-Dichlorobenzamide 217-918-4 2008-58-4 2,6-dichlorobenzamide Not in list C7H5Cl2NO C1=CC(=C(C(=C1)Cl)C(=O)N)Cl InChI=1S/C7H5Cl2NO/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3H,(H2,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 2,6-Dichlorobenzamide 217-918-4 2008-58-4 2,6-dichlorobenzamide Not in list C7H5Cl2NO C1=CC(=C(C(=C1)Cl)C(=O)N)Cl InChI=1S/C7H5Cl2NO/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3H,(H2,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 2,6-Dichlorobenzamide 217-918-4 2008-58-4 2,6-dichlorobenzamide Not in list C7H5Cl2NO C1=CC(=C(C(=C1)Cl)C(=O)N)Cl InChI=1S/C7H5Cl2NO/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3H,(H2,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 2,6-Dichlorobenzamide 217-918-4 2008-58-4 2,6-dichlorobenzamide Not in list C7H5Cl2NO C1=CC(=C(C(=C1)Cl)C(=O)N)Cl InChI=1S/C7H5Cl2NO/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3H,(H2,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 2,6-Dichlorobenzamide 217-918-4 2008-58-4 2,6-dichlorobenzamide Not in list C7H5Cl2NO C1=CC(=C(C(=C1)Cl)C(=O)N)Cl InChI=1S/C7H5Cl2NO/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3H,(H2,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 2,6-Dichlorobenzamide 217-918-4 2008-58-4 2,6-dichlorobenzamide Not in list C7H5Cl2NO C1=CC(=C(C(=C1)Cl)C(=O)N)Cl InChI=1S/C7H5Cl2NO/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3H,(H2,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 2,6-Dichlorobenzamide 217-918-4 2008-58-4 2,6-dichlorobenzamide Not in list C7H5Cl2NO C1=CC(=C(C(=C1)Cl)C(=O)N)Cl InChI=1S/C7H5Cl2NO/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3H,(H2,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 2,6-Dichlorobenzamide 217-918-4 2008-58-4 2,6-dichlorobenzamide Not in list C7H5Cl2NO C1=CC(=C(C(=C1)Cl)C(=O)N)Cl InChI=1S/C7H5Cl2NO/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3H,(H2,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 2,6-Dichlorobenzamide 217-918-4 2008-58-4 2,6-dichlorobenzamide Not in list C7H5Cl2NO C1=CC(=C(C(=C1)Cl)C(=O)N)Cl InChI=1S/C7H5Cl2NO/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3H,(H2,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 2,6-Dichlorobenzamide 217-918-4 2008-58-4 2,6-dichlorobenzamide Not in list C7H5Cl2NO C1=CC(=C(C(=C1)Cl)C(=O)N)Cl InChI=1S/C7H5Cl2NO/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3H,(H2,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 2,6-Dichlorobenzamide 217-918-4 2008-58-4 2,6-dichlorobenzamide Not in list C7H5Cl2NO C1=CC(=C(C(=C1)Cl)C(=O)N)Cl InChI=1S/C7H5Cl2NO/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3H,(H2,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 2,6-Dichlorobenzamide 217-918-4 2008-58-4 2,6-dichlorobenzamide Not in list C7H5Cl2NO C1=CC(=C(C(=C1)Cl)C(=O)N)Cl InChI=1S/C7H5Cl2NO/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3H,(H2,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 2,6-Dichlorobenzamide 217-918-4 2008-58-4 2,6-dichlorobenzamide Not in list C7H5Cl2NO C1=CC(=C(C(=C1)Cl)C(=O)N)Cl InChI=1S/C7H5Cl2NO/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3H,(H2,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 2,6-Dichlorobenzamide 217-918-4 2008-58-4 2,6-dichlorobenzamide Not in list C7H5Cl2NO C1=CC(=C(C(=C1)Cl)C(=O)N)Cl InChI=1S/C7H5Cl2NO/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3H,(H2,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 2,6-Dichlorobenzamide 217-918-4 2008-58-4 2,6-dichlorobenzamide Not in list C7H5Cl2NO C1=CC(=C(C(=C1)Cl)C(=O)N)Cl InChI=1S/C7H5Cl2NO/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3H,(H2,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 2,6-Dichlorobenzamide 217-918-4 2008-58-4 2,6-dichlorobenzamide Not in list C7H5Cl2NO C1=CC(=C(C(=C1)Cl)C(=O)N)Cl InChI=1S/C7H5Cl2NO/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3H,(H2,10,11) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 2,6-Dichlorobenzamide 217-918-4 2008-58-4 2,6-dichlorobenzamide Not in list C7H5Cl2NO C1=CC(=C(C(=C1)Cl)C(=O)N)Cl InChI=1S/C7H5Cl2NO/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3H,(H2,10,11) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable Rat (as animal) Not reported 10 Male/Female oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 2,6-Dichlorobenzamide 217-918-4 2008-58-4 2,6-dichlorobenzamide Not in list C7H5Cl2NO C1=CC(=C(C(=C1)Cl)C(=O)N)Cl InChI=1S/C7H5Cl2NO/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3H,(H2,10,11) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable Rat (as animal) Not reported 10 Male/Female oral: unspecified 48.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 2,6-Dichlorobenzamide 217-918-4 2008-58-4 2,6-dichlorobenzamide Not in list C7H5Cl2NO C1=CC(=C(C(=C1)Cl)C(=O)N)Cl InChI=1S/C7H5Cl2NO/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3H,(H2,10,11) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable Rat (as animal) Not reported 10 Male/Female oral: unspecified 72.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 3-Chloro-5-trifluoromethylpyridine-2-carboxylic acid 3-chloro-5-(trifluoromethyl)pyridine-2-carboxylic acid Not in list C7H3ClF3NO2 Clc1cc(cnc1C(O)=O)C(F)(F)F InChI=1S/C7H3ClF3NO2/c8-4-1-3(7(9,10)11)2-12-5(4)6(13)14/h1-2H,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 3-Chloro-5-trifluoromethylpyridine-2-carboxylic acid 3-chloro-5-(trifluoromethyl)pyridine-2-carboxylic acid Not in list C7H3ClF3NO2 Clc1cc(cnc1C(O)=O)C(F)(F)F InChI=1S/C7H3ClF3NO2/c8-4-1-3(7(9,10)11)2-12-5(4)6(13)14/h1-2H,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 3-Chloro-5-trifluoromethylpyridine-2-carboxylic acid 3-chloro-5-(trifluoromethyl)pyridine-2-carboxylic acid Not in list C7H3ClF3NO2 Clc1cc(cnc1C(O)=O)C(F)(F)F InChI=1S/C7H3ClF3NO2/c8-4-1-3(7(9,10)11)2-12-5(4)6(13)14/h1-2H,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 3-Chloro-5-trifluoromethylpyridine-2-carboxylic acid 3-chloro-5-(trifluoromethyl)pyridine-2-carboxylic acid Not in list C7H3ClF3NO2 Clc1cc(cnc1C(O)=O)C(F)(F)F InChI=1S/C7H3ClF3NO2/c8-4-1-3(7(9,10)11)2-12-5(4)6(13)14/h1-2H,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 3-Chloro-5-trifluoromethylpyridine-2-carboxylic acid 3-chloro-5-(trifluoromethyl)pyridine-2-carboxylic acid Not in list C7H3ClF3NO2 Clc1cc(cnc1C(O)=O)C(F)(F)F InChI=1S/C7H3ClF3NO2/c8-4-1-3(7(9,10)11)2-12-5(4)6(13)14/h1-2H,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 3-Chloro-5-trifluoromethylpyridine-2-carboxylic acid 3-chloro-5-(trifluoromethyl)pyridine-2-carboxylic acid Not in list C7H3ClF3NO2 Clc1cc(cnc1C(O)=O)C(F)(F)F InChI=1S/C7H3ClF3NO2/c8-4-1-3(7(9,10)11)2-12-5(4)6(13)14/h1-2H,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 3-Chloro-5-trifluoromethylpyridine-2-carboxylic acid 3-chloro-5-(trifluoromethyl)pyridine-2-carboxylic acid Not in list C7H3ClF3NO2 Clc1cc(cnc1C(O)=O)C(F)(F)F InChI=1S/C7H3ClF3NO2/c8-4-1-3(7(9,10)11)2-12-5(4)6(13)14/h1-2H,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 3-Chloro-5-trifluoromethylpyridine-2-carboxylic acid 3-chloro-5-(trifluoromethyl)pyridine-2-carboxylic acid Not in list C7H3ClF3NO2 Clc1cc(cnc1C(O)=O)C(F)(F)F InChI=1S/C7H3ClF3NO2/c8-4-1-3(7(9,10)11)2-12-5(4)6(13)14/h1-2H,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 3-Chloro-5-trifluoromethylpyridine-2-carboxylic acid 3-chloro-5-(trifluoromethyl)pyridine-2-carboxylic acid Not in list C7H3ClF3NO2 Clc1cc(cnc1C(O)=O)C(F)(F)F InChI=1S/C7H3ClF3NO2/c8-4-1-3(7(9,10)11)2-12-5(4)6(13)14/h1-2H,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 3-Chloro-5-trifluoromethylpyridine-2-carboxylic acid 3-chloro-5-(trifluoromethyl)pyridine-2-carboxylic acid Not in list C7H3ClF3NO2 Clc1cc(cnc1C(O)=O)C(F)(F)F InChI=1S/C7H3ClF3NO2/c8-4-1-3(7(9,10)11)2-12-5(4)6(13)14/h1-2H,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 3-Chloro-5-trifluoromethylpyridine-2-carboxylic acid 3-chloro-5-(trifluoromethyl)pyridine-2-carboxylic acid Not in list C7H3ClF3NO2 Clc1cc(cnc1C(O)=O)C(F)(F)F InChI=1S/C7H3ClF3NO2/c8-4-1-3(7(9,10)11)2-12-5(4)6(13)14/h1-2H,(H,13,14) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 3-Chloro-5-trifluoromethylpyridine-2-carboxylic acid 3-chloro-5-(trifluoromethyl)pyridine-2-carboxylic acid Not in list C7H3ClF3NO2 Clc1cc(cnc1C(O)=O)C(F)(F)F InChI=1S/C7H3ClF3NO2/c8-4-1-3(7(9,10)11)2-12-5(4)6(13)14/h1-2H,(H,13,14) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 3-Chloro-5-trifluoromethylpyridine-2-carboxylic acid 3-chloro-5-(trifluoromethyl)pyridine-2-carboxylic acid Not in list C7H3ClF3NO2 Clc1cc(cnc1C(O)=O)C(F)(F)F InChI=1S/C7H3ClF3NO2/c8-4-1-3(7(9,10)11)2-12-5(4)6(13)14/h1-2H,(H,13,14) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 3-Chloro-5-trifluoromethylpyridine-2-carboxylic acid 3-chloro-5-(trifluoromethyl)pyridine-2-carboxylic acid Not in list C7H3ClF3NO2 Clc1cc(cnc1C(O)=O)C(F)(F)F InChI=1S/C7H3ClF3NO2/c8-4-1-3(7(9,10)11)2-12-5(4)6(13)14/h1-2H,(H,13,14) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 2,6-dichloro-3-hydroxybenzamide 22818-74-2 2,6-dichloro-3-hydroxybenzamide Not in list C7H5Cl2NO2 C1=CC(=C(C(=C1O)Cl)C(=O)N)Cl InChI=1S/C7H5Cl2NO2/c8-3-1-2-4(11)6(9)5(3)7(10)12/h1-2,11H,(H2,10,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 2,6-dichloro-3-hydroxybenzamide 22818-74-2 2,6-dichloro-3-hydroxybenzamide Not in list C7H5Cl2NO2 C1=CC(=C(C(=C1O)Cl)C(=O)N)Cl InChI=1S/C7H5Cl2NO2/c8-3-1-2-4(11)6(9)5(3)7(10)12/h1-2,11H,(H2,10,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 2,6-dichloro-3-hydroxybenzamide 22818-74-2 2,6-dichloro-3-hydroxybenzamide Not in list C7H5Cl2NO2 C1=CC(=C(C(=C1O)Cl)C(=O)N)Cl InChI=1S/C7H5Cl2NO2/c8-3-1-2-4(11)6(9)5(3)7(10)12/h1-2,11H,(H2,10,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 2,6-dichloro-3-hydroxybenzamide 22818-74-2 2,6-dichloro-3-hydroxybenzamide Not in list C7H5Cl2NO2 C1=CC(=C(C(=C1O)Cl)C(=O)N)Cl InChI=1S/C7H5Cl2NO2/c8-3-1-2-4(11)6(9)5(3)7(10)12/h1-2,11H,(H2,10,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 2,6-dichloro-3-hydroxybenzamide 22818-74-2 2,6-dichloro-3-hydroxybenzamide Not in list C7H5Cl2NO2 C1=CC(=C(C(=C1O)Cl)C(=O)N)Cl InChI=1S/C7H5Cl2NO2/c8-3-1-2-4(11)6(9)5(3)7(10)12/h1-2,11H,(H2,10,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 2,6-dichloro-3-hydroxybenzamide 22818-74-2 2,6-dichloro-3-hydroxybenzamide Not in list C7H5Cl2NO2 C1=CC(=C(C(=C1O)Cl)C(=O)N)Cl InChI=1S/C7H5Cl2NO2/c8-3-1-2-4(11)6(9)5(3)7(10)12/h1-2,11H,(H2,10,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 2,6-dichloro-3-hydroxybenzamide 22818-74-2 2,6-dichloro-3-hydroxybenzamide Not in list C7H5Cl2NO2 C1=CC(=C(C(=C1O)Cl)C(=O)N)Cl InChI=1S/C7H5Cl2NO2/c8-3-1-2-4(11)6(9)5(3)7(10)12/h1-2,11H,(H2,10,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 2,6-dichloro-3-hydroxybenzamide 22818-74-2 2,6-dichloro-3-hydroxybenzamide Not in list C7H5Cl2NO2 C1=CC(=C(C(=C1O)Cl)C(=O)N)Cl InChI=1S/C7H5Cl2NO2/c8-3-1-2-4(11)6(9)5(3)7(10)12/h1-2,11H,(H2,10,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 2,6-dichloro-3-hydroxybenzamide 22818-74-2 2,6-dichloro-3-hydroxybenzamide Not in list C7H5Cl2NO2 C1=CC(=C(C(=C1O)Cl)C(=O)N)Cl InChI=1S/C7H5Cl2NO2/c8-3-1-2-4(11)6(9)5(3)7(10)12/h1-2,11H,(H2,10,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 2,6-dichloro-3-hydroxybenzamide 22818-74-2 2,6-dichloro-3-hydroxybenzamide Not in list C7H5Cl2NO2 C1=CC(=C(C(=C1O)Cl)C(=O)N)Cl InChI=1S/C7H5Cl2NO2/c8-3-1-2-4(11)6(9)5(3)7(10)12/h1-2,11H,(H2,10,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 2,6-dichloro-3-hydroxybenzamide 22818-74-2 2,6-dichloro-3-hydroxybenzamide Not in list C7H5Cl2NO2 C1=CC(=C(C(=C1O)Cl)C(=O)N)Cl InChI=1S/C7H5Cl2NO2/c8-3-1-2-4(11)6(9)5(3)7(10)12/h1-2,11H,(H2,10,12) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 2,6-dichloro-3-hydroxybenzamide 22818-74-2 2,6-dichloro-3-hydroxybenzamide Not in list C7H5Cl2NO2 C1=CC(=C(C(=C1O)Cl)C(=O)N)Cl InChI=1S/C7H5Cl2NO2/c8-3-1-2-4(11)6(9)5(3)7(10)12/h1-2,11H,(H2,10,12) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Positive RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 2,6-dichloro-3-hydroxybenzamide 22818-74-2 2,6-dichloro-3-hydroxybenzamide Not in list C7H5Cl2NO2 C1=CC(=C(C(=C1O)Cl)C(=O)N)Cl InChI=1S/C7H5Cl2NO2/c8-3-1-2-4(11)6(9)5(3)7(10)12/h1-2,11H,(H2,10,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 2,6-dichloro-3-hydroxybenzamide 22818-74-2 2,6-dichloro-3-hydroxybenzamide Not in list C7H5Cl2NO2 C1=CC(=C(C(=C1O)Cl)C(=O)N)Cl InChI=1S/C7H5Cl2NO2/c8-3-1-2-4(11)6(9)5(3)7(10)12/h1-2,11H,(H2,10,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 2,6-dichloro-3-hydroxybenzamide 22818-74-2 2,6-dichloro-3-hydroxybenzamide Not in list C7H5Cl2NO2 C1=CC(=C(C(=C1O)Cl)C(=O)N)Cl InChI=1S/C7H5Cl2NO2/c8-3-1-2-4(11)6(9)5(3)7(10)12/h1-2,11H,(H2,10,12) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male intraperitoneal 24.0000000000 h yes not applicable Negative direct evidence-cytotoxicity RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 2,6-dichloro-3-hydroxybenzamide 22818-74-2 2,6-dichloro-3-hydroxybenzamide Not in list C7H5Cl2NO2 C1=CC(=C(C(=C1O)Cl)C(=O)N)Cl InChI=1S/C7H5Cl2NO2/c8-3-1-2-4(11)6(9)5(3)7(10)12/h1-2,11H,(H2,10,12) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Sprague-Dawley 4 Male oral: gavage 14.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 2,6-dichloro-3-hydroxybenzamide 22818-74-2 2,6-dichloro-3-hydroxybenzamide Not in list C7H5Cl2NO2 C1=CC(=C(C(=C1O)Cl)C(=O)N)Cl InChI=1S/C7H5Cl2NO2/c8-3-1-2-4(11)6(9)5(3)7(10)12/h1-2,11H,(H2,10,12) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Sprague-Dawley 4 Male oral: gavage 2.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 3-Methylsulfinyl-5-trifluoromethylpyridine-2-carboxylic acid 3-(methylsulfinyl)-5-(trifluoromethyl)pyridine-2-carboxylic acid Not in list C8H6F3NO3S OC(=O)c1ncc(cc1S(C)=O)C(F)(F)F InChI=1/C8H6F3NO3S/c1-16(15)5-2-4(8(9,10)11)3-12-6(5)7(13)14/h2-3H,1H3,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 3-Methylsulfinyl-5-trifluoromethylpyridine-2-carboxylic acid 3-(methylsulfinyl)-5-(trifluoromethyl)pyridine-2-carboxylic acid Not in list C8H6F3NO3S OC(=O)c1ncc(cc1S(C)=O)C(F)(F)F InChI=1/C8H6F3NO3S/c1-16(15)5-2-4(8(9,10)11)3-12-6(5)7(13)14/h2-3H,1H3,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 3-Methylsulfinyl-5-trifluoromethylpyridine-2-carboxylic acid 3-(methylsulfinyl)-5-(trifluoromethyl)pyridine-2-carboxylic acid Not in list C8H6F3NO3S OC(=O)c1ncc(cc1S(C)=O)C(F)(F)F InChI=1/C8H6F3NO3S/c1-16(15)5-2-4(8(9,10)11)3-12-6(5)7(13)14/h2-3H,1H3,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 3-Methylsulfinyl-5-trifluoromethylpyridine-2-carboxylic acid 3-(methylsulfinyl)-5-(trifluoromethyl)pyridine-2-carboxylic acid Not in list C8H6F3NO3S OC(=O)c1ncc(cc1S(C)=O)C(F)(F)F InChI=1/C8H6F3NO3S/c1-16(15)5-2-4(8(9,10)11)3-12-6(5)7(13)14/h2-3H,1H3,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 3-Methylsulfinyl-5-trifluoromethylpyridine-2-carboxylic acid 3-(methylsulfinyl)-5-(trifluoromethyl)pyridine-2-carboxylic acid Not in list C8H6F3NO3S OC(=O)c1ncc(cc1S(C)=O)C(F)(F)F InChI=1/C8H6F3NO3S/c1-16(15)5-2-4(8(9,10)11)3-12-6(5)7(13)14/h2-3H,1H3,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 3-Methylsulfinyl-5-trifluoromethylpyridine-2-carboxylic acid 3-(methylsulfinyl)-5-(trifluoromethyl)pyridine-2-carboxylic acid Not in list C8H6F3NO3S OC(=O)c1ncc(cc1S(C)=O)C(F)(F)F InChI=1/C8H6F3NO3S/c1-16(15)5-2-4(8(9,10)11)3-12-6(5)7(13)14/h2-3H,1H3,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 3-Methylsulfinyl-5-trifluoromethylpyridine-2-carboxylic acid 3-(methylsulfinyl)-5-(trifluoromethyl)pyridine-2-carboxylic acid Not in list C8H6F3NO3S OC(=O)c1ncc(cc1S(C)=O)C(F)(F)F InChI=1/C8H6F3NO3S/c1-16(15)5-2-4(8(9,10)11)3-12-6(5)7(13)14/h2-3H,1H3,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 3-Methylsulfinyl-5-trifluoromethylpyridine-2-carboxylic acid 3-(methylsulfinyl)-5-(trifluoromethyl)pyridine-2-carboxylic acid Not in list C8H6F3NO3S OC(=O)c1ncc(cc1S(C)=O)C(F)(F)F InChI=1/C8H6F3NO3S/c1-16(15)5-2-4(8(9,10)11)3-12-6(5)7(13)14/h2-3H,1H3,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 3-Methylsulfinyl-5-trifluoromethylpyridine-2-carboxylic acid 3-(methylsulfinyl)-5-(trifluoromethyl)pyridine-2-carboxylic acid Not in list C8H6F3NO3S OC(=O)c1ncc(cc1S(C)=O)C(F)(F)F InChI=1/C8H6F3NO3S/c1-16(15)5-2-4(8(9,10)11)3-12-6(5)7(13)14/h2-3H,1H3,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 3-Methylsulfinyl-5-trifluoromethylpyridine-2-carboxylic acid 3-(methylsulfinyl)-5-(trifluoromethyl)pyridine-2-carboxylic acid Not in list C8H6F3NO3S OC(=O)c1ncc(cc1S(C)=O)C(F)(F)F InChI=1/C8H6F3NO3S/c1-16(15)5-2-4(8(9,10)11)3-12-6(5)7(13)14/h2-3H,1H3,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 3-Methylsulfinyl-5-trifluoromethylpyridine-2-carboxylic acid 3-(methylsulfinyl)-5-(trifluoromethyl)pyridine-2-carboxylic acid Not in list C8H6F3NO3S OC(=O)c1ncc(cc1S(C)=O)C(F)(F)F InChI=1/C8H6F3NO3S/c1-16(15)5-2-4(8(9,10)11)3-12-6(5)7(13)14/h2-3H,1H3,(H,13,14) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 3-Methylsulfinyl-5-trifluoromethylpyridine-2-carboxylic acid 3-(methylsulfinyl)-5-(trifluoromethyl)pyridine-2-carboxylic acid Not in list C8H6F3NO3S OC(=O)c1ncc(cc1S(C)=O)C(F)(F)F InChI=1/C8H6F3NO3S/c1-16(15)5-2-4(8(9,10)11)3-12-6(5)7(13)14/h2-3H,1H3,(H,13,14) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 3-Methylsulfinyl-5-trifluoromethylpyridine-2-carboxylic acid 3-(methylsulfinyl)-5-(trifluoromethyl)pyridine-2-carboxylic acid Not in list C8H6F3NO3S OC(=O)c1ncc(cc1S(C)=O)C(F)(F)F InChI=1/C8H6F3NO3S/c1-16(15)5-2-4(8(9,10)11)3-12-6(5)7(13)14/h2-3H,1H3,(H,13,14) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 3-Methylsulfinyl-5-trifluoromethylpyridine-2-carboxylic acid 3-(methylsulfinyl)-5-(trifluoromethyl)pyridine-2-carboxylic acid Not in list C8H6F3NO3S OC(=O)c1ncc(cc1S(C)=O)C(F)(F)F InChI=1/C8H6F3NO3S/c1-16(15)5-2-4(8(9,10)11)3-12-6(5)7(13)14/h2-3H,1H3,(H,13,14) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 3-Sulfo-5-trifluoromethyl pyridine-2-carboxylic acid 2-sulfo-4-(trifluoromethyl)benzoic acid Not in list C8H5F3O5S OS(=O)(=O)c1cc(ccc1C(=O)O)C(F)(F)F InChI=1S/C8H5F3O5S/c9-8(10,11)4-1-2-5(7(12)13)6(3-4)17(14,15)16/h1-3H,(H,12,13)(H,14,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 3-Sulfo-5-trifluoromethyl pyridine-2-carboxylic acid 2-sulfo-4-(trifluoromethyl)benzoic acid Not in list C8H5F3O5S OS(=O)(=O)c1cc(ccc1C(=O)O)C(F)(F)F InChI=1S/C8H5F3O5S/c9-8(10,11)4-1-2-5(7(12)13)6(3-4)17(14,15)16/h1-3H,(H,12,13)(H,14,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 3-Sulfo-5-trifluoromethyl pyridine-2-carboxylic acid 2-sulfo-4-(trifluoromethyl)benzoic acid Not in list C8H5F3O5S OS(=O)(=O)c1cc(ccc1C(=O)O)C(F)(F)F InChI=1S/C8H5F3O5S/c9-8(10,11)4-1-2-5(7(12)13)6(3-4)17(14,15)16/h1-3H,(H,12,13)(H,14,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 3-Sulfo-5-trifluoromethyl pyridine-2-carboxylic acid 2-sulfo-4-(trifluoromethyl)benzoic acid Not in list C8H5F3O5S OS(=O)(=O)c1cc(ccc1C(=O)O)C(F)(F)F InChI=1S/C8H5F3O5S/c9-8(10,11)4-1-2-5(7(12)13)6(3-4)17(14,15)16/h1-3H,(H,12,13)(H,14,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 3-Sulfo-5-trifluoromethyl pyridine-2-carboxylic acid 2-sulfo-4-(trifluoromethyl)benzoic acid Not in list C8H5F3O5S OS(=O)(=O)c1cc(ccc1C(=O)O)C(F)(F)F InChI=1S/C8H5F3O5S/c9-8(10,11)4-1-2-5(7(12)13)6(3-4)17(14,15)16/h1-3H,(H,12,13)(H,14,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 3-Sulfo-5-trifluoromethyl pyridine-2-carboxylic acid 2-sulfo-4-(trifluoromethyl)benzoic acid Not in list C8H5F3O5S OS(=O)(=O)c1cc(ccc1C(=O)O)C(F)(F)F InChI=1S/C8H5F3O5S/c9-8(10,11)4-1-2-5(7(12)13)6(3-4)17(14,15)16/h1-3H,(H,12,13)(H,14,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 3-Sulfo-5-trifluoromethyl pyridine-2-carboxylic acid 2-sulfo-4-(trifluoromethyl)benzoic acid Not in list C8H5F3O5S OS(=O)(=O)c1cc(ccc1C(=O)O)C(F)(F)F InChI=1S/C8H5F3O5S/c9-8(10,11)4-1-2-5(7(12)13)6(3-4)17(14,15)16/h1-3H,(H,12,13)(H,14,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 3-Sulfo-5-trifluoromethyl pyridine-2-carboxylic acid 2-sulfo-4-(trifluoromethyl)benzoic acid Not in list C8H5F3O5S OS(=O)(=O)c1cc(ccc1C(=O)O)C(F)(F)F InChI=1S/C8H5F3O5S/c9-8(10,11)4-1-2-5(7(12)13)6(3-4)17(14,15)16/h1-3H,(H,12,13)(H,14,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 3-Sulfo-5-trifluoromethyl pyridine-2-carboxylic acid 2-sulfo-4-(trifluoromethyl)benzoic acid Not in list C8H5F3O5S OS(=O)(=O)c1cc(ccc1C(=O)O)C(F)(F)F InChI=1S/C8H5F3O5S/c9-8(10,11)4-1-2-5(7(12)13)6(3-4)17(14,15)16/h1-3H,(H,12,13)(H,14,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 3-Sulfo-5-trifluoromethyl pyridine-2-carboxylic acid 2-sulfo-4-(trifluoromethyl)benzoic acid Not in list C8H5F3O5S OS(=O)(=O)c1cc(ccc1C(=O)O)C(F)(F)F InChI=1S/C8H5F3O5S/c9-8(10,11)4-1-2-5(7(12)13)6(3-4)17(14,15)16/h1-3H,(H,12,13)(H,14,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 3-Sulfo-5-trifluoromethyl pyridine-2-carboxylic acid 2-sulfo-4-(trifluoromethyl)benzoic acid Not in list C8H5F3O5S OS(=O)(=O)c1cc(ccc1C(=O)O)C(F)(F)F InChI=1S/C8H5F3O5S/c9-8(10,11)4-1-2-5(7(12)13)6(3-4)17(14,15)16/h1-3H,(H,12,13)(H,14,15,16) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 3-Sulfo-5-trifluoromethyl pyridine-2-carboxylic acid 2-sulfo-4-(trifluoromethyl)benzoic acid Not in list C8H5F3O5S OS(=O)(=O)c1cc(ccc1C(=O)O)C(F)(F)F InChI=1S/C8H5F3O5S/c9-8(10,11)4-1-2-5(7(12)13)6(3-4)17(14,15)16/h1-3H,(H,12,13)(H,14,15,16) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 3-Sulfo-5-trifluoromethyl pyridine-2-carboxylic acid 2-sulfo-4-(trifluoromethyl)benzoic acid Not in list C8H5F3O5S OS(=O)(=O)c1cc(ccc1C(=O)O)C(F)(F)F InChI=1S/C8H5F3O5S/c9-8(10,11)4-1-2-5(7(12)13)6(3-4)17(14,15)16/h1-3H,(H,12,13)(H,14,15,16) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Positive RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 3-Sulfo-5-trifluoromethyl pyridine-2-carboxylic acid 2-sulfo-4-(trifluoromethyl)benzoic acid Not in list C8H5F3O5S OS(=O)(=O)c1cc(ccc1C(=O)O)C(F)(F)F InChI=1S/C8H5F3O5S/c9-8(10,11)4-1-2-5(7(12)13)6(3-4)17(14,15)16/h1-3H,(H,12,13)(H,14,15,16) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Positive RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 3-Sulfo-5-trifluoromethyl pyridine-2-carboxylic acid 2-sulfo-4-(trifluoromethyl)benzoic acid Not in list C8H5F3O5S OS(=O)(=O)c1cc(ccc1C(=O)O)C(F)(F)F InChI=1S/C8H5F3O5S/c9-8(10,11)4-1-2-5(7(12)13)6(3-4)17(14,15)16/h1-3H,(H,12,13)(H,14,15,16) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 6 Male intraperitoneal 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 3-Sulfo-5-trifluoromethyl pyridine-2-carboxylic acid 2-sulfo-4-(trifluoromethyl)benzoic acid Not in list C8H5F3O5S OS(=O)(=O)c1cc(ccc1C(=O)O)C(F)(F)F InChI=1S/C8H5F3O5S/c9-8(10,11)4-1-2-5(7(12)13)6(3-4)17(14,15)16/h1-3H,(H,12,13)(H,14,15,16) organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Wistar 4 Male oral: gavage 4.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 3-Sulfo-5-trifluoromethyl pyridine-2-carboxylic acid 2-sulfo-4-(trifluoromethyl)benzoic acid Not in list C8H5F3O5S OS(=O)(=O)c1cc(ccc1C(=O)O)C(F)(F)F InChI=1S/C8H5F3O5S/c9-8(10,11)4-1-2-5(7(12)13)6(3-4)17(14,15)16/h1-3H,(H,12,13)(H,14,15,16) organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Wistar 4 Male oral: gavage 14.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol 3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol Not in list C7H6F3NO3S O=S(C)(=O)c1cc(cnc1O)C(F)(F)F InChI=1/C7H6F3NO3S/c1-15(13,14)5-2-4(7(8,9)10)3-11-6(5)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol 3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol Not in list C7H6F3NO3S O=S(C)(=O)c1cc(cnc1O)C(F)(F)F InChI=1/C7H6F3NO3S/c1-15(13,14)5-2-4(7(8,9)10)3-11-6(5)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol 3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol Not in list C7H6F3NO3S O=S(C)(=O)c1cc(cnc1O)C(F)(F)F InChI=1/C7H6F3NO3S/c1-15(13,14)5-2-4(7(8,9)10)3-11-6(5)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol 3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol Not in list C7H6F3NO3S O=S(C)(=O)c1cc(cnc1O)C(F)(F)F InChI=1/C7H6F3NO3S/c1-15(13,14)5-2-4(7(8,9)10)3-11-6(5)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol 3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol Not in list C7H6F3NO3S O=S(C)(=O)c1cc(cnc1O)C(F)(F)F InChI=1/C7H6F3NO3S/c1-15(13,14)5-2-4(7(8,9)10)3-11-6(5)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol 3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol Not in list C7H6F3NO3S O=S(C)(=O)c1cc(cnc1O)C(F)(F)F InChI=1/C7H6F3NO3S/c1-15(13,14)5-2-4(7(8,9)10)3-11-6(5)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol 3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol Not in list C7H6F3NO3S O=S(C)(=O)c1cc(cnc1O)C(F)(F)F InChI=1/C7H6F3NO3S/c1-15(13,14)5-2-4(7(8,9)10)3-11-6(5)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol 3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol Not in list C7H6F3NO3S O=S(C)(=O)c1cc(cnc1O)C(F)(F)F InChI=1/C7H6F3NO3S/c1-15(13,14)5-2-4(7(8,9)10)3-11-6(5)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol 3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol Not in list C7H6F3NO3S O=S(C)(=O)c1cc(cnc1O)C(F)(F)F InChI=1/C7H6F3NO3S/c1-15(13,14)5-2-4(7(8,9)10)3-11-6(5)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol 3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol Not in list C7H6F3NO3S O=S(C)(=O)c1cc(cnc1O)C(F)(F)F InChI=1/C7H6F3NO3S/c1-15(13,14)5-2-4(7(8,9)10)3-11-6(5)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol 3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol Not in list C7H6F3NO3S O=S(C)(=O)c1cc(cnc1O)C(F)(F)F InChI=1/C7H6F3NO3S/c1-15(13,14)5-2-4(7(8,9)10)3-11-6(5)12/h2-3H,1H3,(H,11,12) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Positive RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol 3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol Not in list C7H6F3NO3S O=S(C)(=O)c1cc(cnc1O)C(F)(F)F InChI=1/C7H6F3NO3S/c1-15(13,14)5-2-4(7(8,9)10)3-11-6(5)12/h2-3H,1H3,(H,11,12) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Positive RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol 3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol Not in list C7H6F3NO3S O=S(C)(=O)c1cc(cnc1O)C(F)(F)F InChI=1/C7H6F3NO3S/c1-15(13,14)5-2-4(7(8,9)10)3-11-6(5)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol 3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol Not in list C7H6F3NO3S O=S(C)(=O)c1cc(cnc1O)C(F)(F)F InChI=1/C7H6F3NO3S/c1-15(13,14)5-2-4(7(8,9)10)3-11-6(5)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol 3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol Not in list C7H6F3NO3S O=S(C)(=O)c1cc(cnc1O)C(F)(F)F InChI=1/C7H6F3NO3S/c1-15(13,14)5-2-4(7(8,9)10)3-11-6(5)12/h2-3H,1H3,(H,11,12) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 Male intraperitoneal 24.0000000000 yes, concurrent vehicle not applicable Negative no evidence RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol 3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol Not in list C7H6F3NO3S O=S(C)(=O)c1cc(cnc1O)C(F)(F)F InChI=1/C7H6F3NO3S/c1-15(13,14)5-2-4(7(8,9)10)3-11-6(5)12/h2-3H,1H3,(H,11,12) organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Wistar 4 Male Not reported 14.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Fluopicolide 239110-15-7 single chemical entity Component is a metabolite of the substance 3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol 3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol Not in list C7H6F3NO3S O=S(C)(=O)c1cc(cnc1O)C(F)(F)F InChI=1/C7H6F3NO3S/c1-15(13,14)5-2-4(7(8,9)10)3-11-6(5)12/h2-3H,1H3,(H,11,12) organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Wistar 4 Male Not reported 4.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Fluopicolide 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fluopicolide 09Jul2009 2009 doi:10.2903/j.efsa.2009.299r
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is identical to the substance Tembotrione 608-879-8 335104-84-2 2-[2-chloro-4-methylsulfonyl-3-(2,2,2-trifluoroethoxymethyl)benzoyl]cyclohexane-1,3-dione Tembotrione C17H16ClF3O6S CS(=O)(=O)C1=C(C(=C(C=C1)C(=O)C2C(=O)CCCC2=O)Cl)COCC(F)(F)F InChI=1S/C17H16ClF3O6S/c1-28(25,26)13-6-5-9(15(18)10(13)7-27-8-17(19,20)21)16(24)14-11(22)3-2-4-12(14)23/h5-6,14H,2-4,7-8H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle without Negative RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is identical to the substance Tembotrione 608-879-8 335104-84-2 2-[2-chloro-4-methylsulfonyl-3-(2,2,2-trifluoroethoxymethyl)benzoyl]cyclohexane-1,3-dione Tembotrione C17H16ClF3O6S CS(=O)(=O)C1=C(C(=C(C=C1)C(=O)C2C(=O)CCCC2=O)Cl)COCC(F)(F)F InChI=1S/C17H16ClF3O6S/c1-28(25,26)13-6-5-9(15(18)10(13)7-27-8-17(19,20)21)16(24)14-11(22)3-2-4-12(14)23/h5-6,14H,2-4,7-8H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is identical to the substance Tembotrione 608-879-8 335104-84-2 2-[2-chloro-4-methylsulfonyl-3-(2,2,2-trifluoroethoxymethyl)benzoyl]cyclohexane-1,3-dione Tembotrione C17H16ClF3O6S CS(=O)(=O)C1=C(C(=C(C=C1)C(=O)C2C(=O)CCCC2=O)Cl)COCC(F)(F)F InChI=1S/C17H16ClF3O6S/c1-28(25,26)13-6-5-9(15(18)10(13)7-27-8-17(19,20)21)16(24)14-11(22)3-2-4-12(14)23/h5-6,14H,2-4,7-8H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is identical to the substance Tembotrione 608-879-8 335104-84-2 2-[2-chloro-4-methylsulfonyl-3-(2,2,2-trifluoroethoxymethyl)benzoyl]cyclohexane-1,3-dione Tembotrione C17H16ClF3O6S CS(=O)(=O)C1=C(C(=C(C=C1)C(=O)C2C(=O)CCCC2=O)Cl)COCC(F)(F)F InChI=1S/C17H16ClF3O6S/c1-28(25,26)13-6-5-9(15(18)10(13)7-27-8-17(19,20)21)16(24)14-11(22)3-2-4-12(14)23/h5-6,14H,2-4,7-8H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is identical to the substance Tembotrione 608-879-8 335104-84-2 2-[2-chloro-4-methylsulfonyl-3-(2,2,2-trifluoroethoxymethyl)benzoyl]cyclohexane-1,3-dione Tembotrione C17H16ClF3O6S CS(=O)(=O)C1=C(C(=C(C=C1)C(=O)C2C(=O)CCCC2=O)Cl)COCC(F)(F)F InChI=1S/C17H16ClF3O6S/c1-28(25,26)13-6-5-9(15(18)10(13)7-27-8-17(19,20)21)16(24)14-11(22)3-2-4-12(14)23/h5-6,14H,2-4,7-8H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is identical to the substance Tembotrione 608-879-8 335104-84-2 2-[2-chloro-4-methylsulfonyl-3-(2,2,2-trifluoroethoxymethyl)benzoyl]cyclohexane-1,3-dione Tembotrione C17H16ClF3O6S CS(=O)(=O)C1=C(C(=C(C=C1)C(=O)C2C(=O)CCCC2=O)Cl)COCC(F)(F)F InChI=1S/C17H16ClF3O6S/c1-28(25,26)13-6-5-9(15(18)10(13)7-27-8-17(19,20)21)16(24)14-11(22)3-2-4-12(14)23/h5-6,14H,2-4,7-8H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is identical to the substance Tembotrione 608-879-8 335104-84-2 2-[2-chloro-4-methylsulfonyl-3-(2,2,2-trifluoroethoxymethyl)benzoyl]cyclohexane-1,3-dione Tembotrione C17H16ClF3O6S CS(=O)(=O)C1=C(C(=C(C=C1)C(=O)C2C(=O)CCCC2=O)Cl)COCC(F)(F)F InChI=1S/C17H16ClF3O6S/c1-28(25,26)13-6-5-9(15(18)10(13)7-27-8-17(19,20)21)16(24)14-11(22)3-2-4-12(14)23/h5-6,14H,2-4,7-8H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle with Negative RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is identical to the substance Tembotrione 608-879-8 335104-84-2 2-[2-chloro-4-methylsulfonyl-3-(2,2,2-trifluoroethoxymethyl)benzoyl]cyclohexane-1,3-dione Tembotrione C17H16ClF3O6S CS(=O)(=O)C1=C(C(=C(C=C1)C(=O)C2C(=O)CCCC2=O)Cl)COCC(F)(F)F InChI=1S/C17H16ClF3O6S/c1-28(25,26)13-6-5-9(15(18)10(13)7-27-8-17(19,20)21)16(24)14-11(22)3-2-4-12(14)23/h5-6,14H,2-4,7-8H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is identical to the substance Tembotrione 608-879-8 335104-84-2 2-[2-chloro-4-methylsulfonyl-3-(2,2,2-trifluoroethoxymethyl)benzoyl]cyclohexane-1,3-dione Tembotrione C17H16ClF3O6S CS(=O)(=O)C1=C(C(=C(C=C1)C(=O)C2C(=O)CCCC2=O)Cl)COCC(F)(F)F InChI=1S/C17H16ClF3O6S/c1-28(25,26)13-6-5-9(15(18)10(13)7-27-8-17(19,20)21)16(24)14-11(22)3-2-4-12(14)23/h5-6,14H,2-4,7-8H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is identical to the substance Tembotrione 608-879-8 335104-84-2 2-[2-chloro-4-methylsulfonyl-3-(2,2,2-trifluoroethoxymethyl)benzoyl]cyclohexane-1,3-dione Tembotrione C17H16ClF3O6S CS(=O)(=O)C1=C(C(=C(C=C1)C(=O)C2C(=O)CCCC2=O)Cl)COCC(F)(F)F InChI=1S/C17H16ClF3O6S/c1-28(25,26)13-6-5-9(15(18)10(13)7-27-8-17(19,20)21)16(24)14-11(22)3-2-4-12(14)23/h5-6,14H,2-4,7-8H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is identical to the substance Tembotrione 608-879-8 335104-84-2 2-[2-chloro-4-methylsulfonyl-3-(2,2,2-trifluoroethoxymethyl)benzoyl]cyclohexane-1,3-dione Tembotrione C17H16ClF3O6S CS(=O)(=O)C1=C(C(=C(C=C1)C(=O)C2C(=O)CCCC2=O)Cl)COCC(F)(F)F InChI=1S/C17H16ClF3O6S/c1-28(25,26)13-6-5-9(15(18)10(13)7-27-8-17(19,20)21)16(24)14-11(22)3-2-4-12(14)23/h5-6,14H,2-4,7-8H2,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Positive RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is identical to the substance Tembotrione 608-879-8 335104-84-2 2-[2-chloro-4-methylsulfonyl-3-(2,2,2-trifluoroethoxymethyl)benzoyl]cyclohexane-1,3-dione Tembotrione C17H16ClF3O6S CS(=O)(=O)C1=C(C(=C(C=C1)C(=O)C2C(=O)CCCC2=O)Cl)COCC(F)(F)F InChI=1S/C17H16ClF3O6S/c1-28(25,26)13-6-5-9(15(18)10(13)7-27-8-17(19,20)21)16(24)14-11(22)3-2-4-12(14)23/h5-6,14H,2-4,7-8H2,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Positive RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is identical to the substance Tembotrione 608-879-8 335104-84-2 2-[2-chloro-4-methylsulfonyl-3-(2,2,2-trifluoroethoxymethyl)benzoyl]cyclohexane-1,3-dione Tembotrione C17H16ClF3O6S CS(=O)(=O)C1=C(C(=C(C=C1)C(=O)C2C(=O)CCCC2=O)Cl)COCC(F)(F)F InChI=1S/C17H16ClF3O6S/c1-28(25,26)13-6-5-9(15(18)10(13)7-27-8-17(19,20)21)16(24)14-11(22)3-2-4-12(14)23/h5-6,14H,2-4,7-8H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is identical to the substance Tembotrione 608-879-8 335104-84-2 2-[2-chloro-4-methylsulfonyl-3-(2,2,2-trifluoroethoxymethyl)benzoyl]cyclohexane-1,3-dione Tembotrione C17H16ClF3O6S CS(=O)(=O)C1=C(C(=C(C=C1)C(=O)C2C(=O)CCCC2=O)Cl)COCC(F)(F)F InChI=1S/C17H16ClF3O6S/c1-28(25,26)13-6-5-9(15(18)10(13)7-27-8-17(19,20)21)16(24)14-11(22)3-2-4-12(14)23/h5-6,14H,2-4,7-8H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is identical to the substance Tembotrione 608-879-8 335104-84-2 2-[2-chloro-4-methylsulfonyl-3-(2,2,2-trifluoroethoxymethyl)benzoyl]cyclohexane-1,3-dione Tembotrione C17H16ClF3O6S CS(=O)(=O)C1=C(C(=C(C=C1)C(=O)C2C(=O)CCCC2=O)Cl)COCC(F)(F)F InChI=1S/C17H16ClF3O6S/c1-28(25,26)13-6-5-9(15(18)10(13)7-27-8-17(19,20)21)16(24)14-11(22)3-2-4-12(14)23/h5-6,14H,2-4,7-8H2,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 7 Male oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is identical to the substance Tembotrione 608-879-8 335104-84-2 2-[2-chloro-4-methylsulfonyl-3-(2,2,2-trifluoroethoxymethyl)benzoyl]cyclohexane-1,3-dione Tembotrione C17H16ClF3O6S CS(=O)(=O)C1=C(C(=C(C=C1)C(=O)C2C(=O)CCCC2=O)Cl)COCC(F)(F)F InChI=1S/C17H16ClF3O6S/c1-28(25,26)13-6-5-9(15(18)10(13)7-27-8-17(19,20)21)16(24)14-11(22)3-2-4-12(14)23/h5-6,14H,2-4,7-8H2,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 7 Male oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is identical to the substance Tembotrione 608-879-8 335104-84-2 2-[2-chloro-4-methylsulfonyl-3-(2,2,2-trifluoroethoxymethyl)benzoyl]cyclohexane-1,3-dione Tembotrione C17H16ClF3O6S CS(=O)(=O)C1=C(C(=C(C=C1)C(=O)C2C(=O)CCCC2=O)Cl)COCC(F)(F)F InChI=1S/C17H16ClF3O6S/c1-28(25,26)13-6-5-9(15(18)10(13)7-27-8-17(19,20)21)16(24)14-11(22)3-2-4-12(14)23/h5-6,14H,2-4,7-8H2,1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Wistar 3 Male oral: gavage 4.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is identical to the substance Tembotrione 608-879-8 335104-84-2 2-[2-chloro-4-methylsulfonyl-3-(2,2,2-trifluoroethoxymethyl)benzoyl]cyclohexane-1,3-dione Tembotrione C17H16ClF3O6S CS(=O)(=O)C1=C(C(=C(C=C1)C(=O)C2C(=O)CCCC2=O)Cl)COCC(F)(F)F InChI=1S/C17H16ClF3O6S/c1-28(25,26)13-6-5-9(15(18)10(13)7-27-8-17(19,20)21)16(24)14-11(22)3-2-4-12(14)23/h5-6,14H,2-4,7-8H2,1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Wistar 3 Male oral: gavage 16.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is a metabolite of the substance 2-Chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]benzoic acid 2-chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]benzoic acid Not in list C11H10ClF3O5S OC(=O)c1ccc(c(COCC(F)(F)F)c1Cl)S(C)(=O)=O InChI=1/C11H10ClF3O5S/c1-21(18,19)8-3-2-6(10(16)17)9(12)7(8)4-20-5-11(13,14)15/h2-3H,4-5H2,1H3,(H,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent no treatment with Negative RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is a metabolite of the substance 2-Chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]benzoic acid 2-chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]benzoic acid Not in list C11H10ClF3O5S OC(=O)c1ccc(c(COCC(F)(F)F)c1Cl)S(C)(=O)=O InChI=1/C11H10ClF3O5S/c1-21(18,19)8-3-2-6(10(16)17)9(12)7(8)4-20-5-11(13,14)15/h2-3H,4-5H2,1H3,(H,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent no treatment with Negative RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is a metabolite of the substance 2-Chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]benzoic acid 2-chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]benzoic acid Not in list C11H10ClF3O5S OC(=O)c1ccc(c(COCC(F)(F)F)c1Cl)S(C)(=O)=O InChI=1/C11H10ClF3O5S/c1-21(18,19)8-3-2-6(10(16)17)9(12)7(8)4-20-5-11(13,14)15/h2-3H,4-5H2,1H3,(H,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent no treatment without Negative RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is a metabolite of the substance 2-Chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]benzoic acid 2-chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]benzoic acid Not in list C11H10ClF3O5S OC(=O)c1ccc(c(COCC(F)(F)F)c1Cl)S(C)(=O)=O InChI=1/C11H10ClF3O5S/c1-21(18,19)8-3-2-6(10(16)17)9(12)7(8)4-20-5-11(13,14)15/h2-3H,4-5H2,1H3,(H,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent no treatment without Negative RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is a metabolite of the substance 2-Chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]benzoic acid 2-chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]benzoic acid Not in list C11H10ClF3O5S OC(=O)c1ccc(c(COCC(F)(F)F)c1Cl)S(C)(=O)=O InChI=1/C11H10ClF3O5S/c1-21(18,19)8-3-2-6(10(16)17)9(12)7(8)4-20-5-11(13,14)15/h2-3H,4-5H2,1H3,(H,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent no treatment without Negative RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is a metabolite of the substance 2-Chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]benzoic acid 2-chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]benzoic acid Not in list C11H10ClF3O5S OC(=O)c1ccc(c(COCC(F)(F)F)c1Cl)S(C)(=O)=O InChI=1/C11H10ClF3O5S/c1-21(18,19)8-3-2-6(10(16)17)9(12)7(8)4-20-5-11(13,14)15/h2-3H,4-5H2,1H3,(H,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent no treatment without Negative RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is a metabolite of the substance 2-Chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]benzoic acid 2-chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]benzoic acid Not in list C11H10ClF3O5S OC(=O)c1ccc(c(COCC(F)(F)F)c1Cl)S(C)(=O)=O InChI=1/C11H10ClF3O5S/c1-21(18,19)8-3-2-6(10(16)17)9(12)7(8)4-20-5-11(13,14)15/h2-3H,4-5H2,1H3,(H,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent no treatment with Negative RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is a metabolite of the substance 2-Chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]benzoic acid 2-chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]benzoic acid Not in list C11H10ClF3O5S OC(=O)c1ccc(c(COCC(F)(F)F)c1Cl)S(C)(=O)=O InChI=1/C11H10ClF3O5S/c1-21(18,19)8-3-2-6(10(16)17)9(12)7(8)4-20-5-11(13,14)15/h2-3H,4-5H2,1H3,(H,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent no treatment with Negative RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is a metabolite of the substance 2-Chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]benzoic acid 2-chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]benzoic acid Not in list C11H10ClF3O5S OC(=O)c1ccc(c(COCC(F)(F)F)c1Cl)S(C)(=O)=O InChI=1/C11H10ClF3O5S/c1-21(18,19)8-3-2-6(10(16)17)9(12)7(8)4-20-5-11(13,14)15/h2-3H,4-5H2,1H3,(H,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent no treatment with Negative RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is a metabolite of the substance 2-Chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]benzoic acid 2-chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]benzoic acid Not in list C11H10ClF3O5S OC(=O)c1ccc(c(COCC(F)(F)F)c1Cl)S(C)(=O)=O InChI=1/C11H10ClF3O5S/c1-21(18,19)8-3-2-6(10(16)17)9(12)7(8)4-20-5-11(13,14)15/h2-3H,4-5H2,1H3,(H,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent no treatment without Negative RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is a metabolite of the substance 2-Chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]benzoic acid 2-chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]benzoic acid Not in list C11H10ClF3O5S OC(=O)c1ccc(c(COCC(F)(F)F)c1Cl)S(C)(=O)=O InChI=1/C11H10ClF3O5S/c1-21(18,19)8-3-2-6(10(16)17)9(12)7(8)4-20-5-11(13,14)15/h2-3H,4-5H2,1H3,(H,16,17) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent no treatment with Negative RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is a metabolite of the substance 2-Chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]benzoic acid 2-chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]benzoic acid Not in list C11H10ClF3O5S OC(=O)c1ccc(c(COCC(F)(F)F)c1Cl)S(C)(=O)=O InChI=1/C11H10ClF3O5S/c1-21(18,19)8-3-2-6(10(16)17)9(12)7(8)4-20-5-11(13,14)15/h2-3H,4-5H2,1H3,(H,16,17) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent no treatment without Negative RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is a metabolite of the substance 2-Chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]benzoic acid 2-chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]benzoic acid Not in list C11H10ClF3O5S OC(=O)c1ccc(c(COCC(F)(F)F)c1Cl)S(C)(=O)=O InChI=1/C11H10ClF3O5S/c1-21(18,19)8-3-2-6(10(16)17)9(12)7(8)4-20-5-11(13,14)15/h2-3H,4-5H2,1H3,(H,16,17) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent no treatment without Negative RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is a metabolite of the substance 2-Chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]benzoic acid 2-chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]benzoic acid Not in list C11H10ClF3O5S OC(=O)c1ccc(c(COCC(F)(F)F)c1Cl)S(C)(=O)=O InChI=1/C11H10ClF3O5S/c1-21(18,19)8-3-2-6(10(16)17)9(12)7(8)4-20-5-11(13,14)15/h2-3H,4-5H2,1H3,(H,16,17) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent no treatment with Negative RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is a metabolite of the substance 2-{2-Chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy) methyl]benzoyl}-4,6-dihydroxycyclohexane-1,3-dione 2-({2-chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]phenyl}carbonyl)-4,6-dihydroxycyclohexane-1,3-dione Tembotrione metabolite M5 (Dihydroxy-tembotrione) C17H16ClF3O8S O=C1C(C(=O)C(O)CC1O)C(=O)c2ccc(c(COCC(F)(F)F)c2Cl)S(C)(=O)=O InChI=1/C17H16ClF3O8S/c1-30(27,28)11-3-2-7(13(18)8(11)5-29-6-17(19,20)21)14(24)12-15(25)9(22)4-10(23)16(12)26/h2-3,9-10,12,22-23H,4-6H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is a metabolite of the substance 2-{2-Chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy) methyl]benzoyl}-4,6-dihydroxycyclohexane-1,3-dione 2-({2-chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]phenyl}carbonyl)-4,6-dihydroxycyclohexane-1,3-dione Tembotrione metabolite M5 (Dihydroxy-tembotrione) C17H16ClF3O8S O=C1C(C(=O)C(O)CC1O)C(=O)c2ccc(c(COCC(F)(F)F)c2Cl)S(C)(=O)=O InChI=1/C17H16ClF3O8S/c1-30(27,28)11-3-2-7(13(18)8(11)5-29-6-17(19,20)21)14(24)12-15(25)9(22)4-10(23)16(12)26/h2-3,9-10,12,22-23H,4-6H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is a metabolite of the substance 2-{2-Chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy) methyl]benzoyl}-4,6-dihydroxycyclohexane-1,3-dione 2-({2-chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]phenyl}carbonyl)-4,6-dihydroxycyclohexane-1,3-dione Tembotrione metabolite M5 (Dihydroxy-tembotrione) C17H16ClF3O8S O=C1C(C(=O)C(O)CC1O)C(=O)c2ccc(c(COCC(F)(F)F)c2Cl)S(C)(=O)=O InChI=1/C17H16ClF3O8S/c1-30(27,28)11-3-2-7(13(18)8(11)5-29-6-17(19,20)21)14(24)12-15(25)9(22)4-10(23)16(12)26/h2-3,9-10,12,22-23H,4-6H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is a metabolite of the substance 2-{2-Chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy) methyl]benzoyl}-4,6-dihydroxycyclohexane-1,3-dione 2-({2-chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]phenyl}carbonyl)-4,6-dihydroxycyclohexane-1,3-dione Tembotrione metabolite M5 (Dihydroxy-tembotrione) C17H16ClF3O8S O=C1C(C(=O)C(O)CC1O)C(=O)c2ccc(c(COCC(F)(F)F)c2Cl)S(C)(=O)=O InChI=1/C17H16ClF3O8S/c1-30(27,28)11-3-2-7(13(18)8(11)5-29-6-17(19,20)21)14(24)12-15(25)9(22)4-10(23)16(12)26/h2-3,9-10,12,22-23H,4-6H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is a metabolite of the substance 2-{2-Chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy) methyl]benzoyl}-4,6-dihydroxycyclohexane-1,3-dione 2-({2-chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]phenyl}carbonyl)-4,6-dihydroxycyclohexane-1,3-dione Tembotrione metabolite M5 (Dihydroxy-tembotrione) C17H16ClF3O8S O=C1C(C(=O)C(O)CC1O)C(=O)c2ccc(c(COCC(F)(F)F)c2Cl)S(C)(=O)=O InChI=1/C17H16ClF3O8S/c1-30(27,28)11-3-2-7(13(18)8(11)5-29-6-17(19,20)21)14(24)12-15(25)9(22)4-10(23)16(12)26/h2-3,9-10,12,22-23H,4-6H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is a metabolite of the substance 2-{2-Chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy) methyl]benzoyl}-4,6-dihydroxycyclohexane-1,3-dione 2-({2-chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]phenyl}carbonyl)-4,6-dihydroxycyclohexane-1,3-dione Tembotrione metabolite M5 (Dihydroxy-tembotrione) C17H16ClF3O8S O=C1C(C(=O)C(O)CC1O)C(=O)c2ccc(c(COCC(F)(F)F)c2Cl)S(C)(=O)=O InChI=1/C17H16ClF3O8S/c1-30(27,28)11-3-2-7(13(18)8(11)5-29-6-17(19,20)21)14(24)12-15(25)9(22)4-10(23)16(12)26/h2-3,9-10,12,22-23H,4-6H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is a metabolite of the substance 2-{2-Chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy) methyl]benzoyl}-4,6-dihydroxycyclohexane-1,3-dione 2-({2-chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]phenyl}carbonyl)-4,6-dihydroxycyclohexane-1,3-dione Tembotrione metabolite M5 (Dihydroxy-tembotrione) C17H16ClF3O8S O=C1C(C(=O)C(O)CC1O)C(=O)c2ccc(c(COCC(F)(F)F)c2Cl)S(C)(=O)=O InChI=1/C17H16ClF3O8S/c1-30(27,28)11-3-2-7(13(18)8(11)5-29-6-17(19,20)21)14(24)12-15(25)9(22)4-10(23)16(12)26/h2-3,9-10,12,22-23H,4-6H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is a metabolite of the substance 2-{2-Chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy) methyl]benzoyl}-4,6-dihydroxycyclohexane-1,3-dione 2-({2-chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]phenyl}carbonyl)-4,6-dihydroxycyclohexane-1,3-dione Tembotrione metabolite M5 (Dihydroxy-tembotrione) C17H16ClF3O8S O=C1C(C(=O)C(O)CC1O)C(=O)c2ccc(c(COCC(F)(F)F)c2Cl)S(C)(=O)=O InChI=1/C17H16ClF3O8S/c1-30(27,28)11-3-2-7(13(18)8(11)5-29-6-17(19,20)21)14(24)12-15(25)9(22)4-10(23)16(12)26/h2-3,9-10,12,22-23H,4-6H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is a metabolite of the substance 2-{2-Chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy) methyl]benzoyl}-4,6-dihydroxycyclohexane-1,3-dione 2-({2-chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]phenyl}carbonyl)-4,6-dihydroxycyclohexane-1,3-dione Tembotrione metabolite M5 (Dihydroxy-tembotrione) C17H16ClF3O8S O=C1C(C(=O)C(O)CC1O)C(=O)c2ccc(c(COCC(F)(F)F)c2Cl)S(C)(=O)=O InChI=1/C17H16ClF3O8S/c1-30(27,28)11-3-2-7(13(18)8(11)5-29-6-17(19,20)21)14(24)12-15(25)9(22)4-10(23)16(12)26/h2-3,9-10,12,22-23H,4-6H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is a metabolite of the substance 2-{2-Chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy) methyl]benzoyl}-4,6-dihydroxycyclohexane-1,3-dione 2-({2-chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]phenyl}carbonyl)-4,6-dihydroxycyclohexane-1,3-dione Tembotrione metabolite M5 (Dihydroxy-tembotrione) C17H16ClF3O8S O=C1C(C(=O)C(O)CC1O)C(=O)c2ccc(c(COCC(F)(F)F)c2Cl)S(C)(=O)=O InChI=1/C17H16ClF3O8S/c1-30(27,28)11-3-2-7(13(18)8(11)5-29-6-17(19,20)21)14(24)12-15(25)9(22)4-10(23)16(12)26/h2-3,9-10,12,22-23H,4-6H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is a metabolite of the substance 2-{2-Chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy) methyl]benzoyl}-4,6-dihydroxycyclohexane-1,3-dione 2-({2-chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]phenyl}carbonyl)-4,6-dihydroxycyclohexane-1,3-dione Tembotrione metabolite M5 (Dihydroxy-tembotrione) C17H16ClF3O8S O=C1C(C(=O)C(O)CC1O)C(=O)c2ccc(c(COCC(F)(F)F)c2Cl)S(C)(=O)=O InChI=1/C17H16ClF3O8S/c1-30(27,28)11-3-2-7(13(18)8(11)5-29-6-17(19,20)21)14(24)12-15(25)9(22)4-10(23)16(12)26/h2-3,9-10,12,22-23H,4-6H2,1H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent no treatment without Negative RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is a metabolite of the substance 2-{2-Chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy) methyl]benzoyl}-4,6-dihydroxycyclohexane-1,3-dione 2-({2-chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]phenyl}carbonyl)-4,6-dihydroxycyclohexane-1,3-dione Tembotrione metabolite M5 (Dihydroxy-tembotrione) C17H16ClF3O8S O=C1C(C(=O)C(O)CC1O)C(=O)c2ccc(c(COCC(F)(F)F)c2Cl)S(C)(=O)=O InChI=1/C17H16ClF3O8S/c1-30(27,28)11-3-2-7(13(18)8(11)5-29-6-17(19,20)21)14(24)12-15(25)9(22)4-10(23)16(12)26/h2-3,9-10,12,22-23H,4-6H2,1H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent no treatment with Negative RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is a metabolite of the substance 2-{2-Chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy) methyl]benzoyl}-4,6-dihydroxycyclohexane-1,3-dione 2-({2-chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]phenyl}carbonyl)-4,6-dihydroxycyclohexane-1,3-dione Tembotrione metabolite M5 (Dihydroxy-tembotrione) C17H16ClF3O8S O=C1C(C(=O)C(O)CC1O)C(=O)c2ccc(c(COCC(F)(F)F)c2Cl)S(C)(=O)=O InChI=1/C17H16ClF3O8S/c1-30(27,28)11-3-2-7(13(18)8(11)5-29-6-17(19,20)21)14(24)12-15(25)9(22)4-10(23)16(12)26/h2-3,9-10,12,22-23H,4-6H2,1H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative no information RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is a metabolite of the substance 2-{2-Chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy) methyl]benzoyl}-4,6-dihydroxycyclohexane-1,3-dione 2-({2-chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]phenyl}carbonyl)-4,6-dihydroxycyclohexane-1,3-dione Tembotrione metabolite M5 (Dihydroxy-tembotrione) C17H16ClF3O8S O=C1C(C(=O)C(O)CC1O)C(=O)c2ccc(c(COCC(F)(F)F)c2Cl)S(C)(=O)=O InChI=1/C17H16ClF3O8S/c1-30(27,28)11-3-2-7(13(18)8(11)5-29-6-17(19,20)21)14(24)12-15(25)9(22)4-10(23)16(12)26/h2-3,9-10,12,22-23H,4-6H2,1H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Negative no information RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is a metabolite of the substance 2-Chloro-3-(hydroxymethyl)-4-(methylsulfonyl)benzoic acid 2-chloro-3-(hydroxymethyl)-4-(methylsulfonyl)benzoic acid Not in list C9H9ClO5S OC(=O)c1ccc(c(CO)c1Cl)S(C)(=O)=O InChI=1/C9H9ClO5S/c1-16(14,15)7-3-2-5(9(12)13)8(10)6(7)4-11/h2-3,11H,4H2,1H3,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is a metabolite of the substance 2-Chloro-3-(hydroxymethyl)-4-(methylsulfonyl)benzoic acid 2-chloro-3-(hydroxymethyl)-4-(methylsulfonyl)benzoic acid Not in list C9H9ClO5S OC(=O)c1ccc(c(CO)c1Cl)S(C)(=O)=O InChI=1/C9H9ClO5S/c1-16(14,15)7-3-2-5(9(12)13)8(10)6(7)4-11/h2-3,11H,4H2,1H3,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is a metabolite of the substance 2-Chloro-3-(hydroxymethyl)-4-(methylsulfonyl)benzoic acid 2-chloro-3-(hydroxymethyl)-4-(methylsulfonyl)benzoic acid Not in list C9H9ClO5S OC(=O)c1ccc(c(CO)c1Cl)S(C)(=O)=O InChI=1/C9H9ClO5S/c1-16(14,15)7-3-2-5(9(12)13)8(10)6(7)4-11/h2-3,11H,4H2,1H3,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is a metabolite of the substance 2-Chloro-3-(hydroxymethyl)-4-(methylsulfonyl)benzoic acid 2-chloro-3-(hydroxymethyl)-4-(methylsulfonyl)benzoic acid Not in list C9H9ClO5S OC(=O)c1ccc(c(CO)c1Cl)S(C)(=O)=O InChI=1/C9H9ClO5S/c1-16(14,15)7-3-2-5(9(12)13)8(10)6(7)4-11/h2-3,11H,4H2,1H3,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes without Negative RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is a metabolite of the substance 2-Chloro-3-(hydroxymethyl)-4-(methylsulfonyl)benzoic acid 2-chloro-3-(hydroxymethyl)-4-(methylsulfonyl)benzoic acid Not in list C9H9ClO5S OC(=O)c1ccc(c(CO)c1Cl)S(C)(=O)=O InChI=1/C9H9ClO5S/c1-16(14,15)7-3-2-5(9(12)13)8(10)6(7)4-11/h2-3,11H,4H2,1H3,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is a metabolite of the substance 2-Chloro-3-(hydroxymethyl)-4-(methylsulfonyl)benzoic acid 2-chloro-3-(hydroxymethyl)-4-(methylsulfonyl)benzoic acid Not in list C9H9ClO5S OC(=O)c1ccc(c(CO)c1Cl)S(C)(=O)=O InChI=1/C9H9ClO5S/c1-16(14,15)7-3-2-5(9(12)13)8(10)6(7)4-11/h2-3,11H,4H2,1H3,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is a metabolite of the substance 2-Chloro-3-(hydroxymethyl)-4-(methylsulfonyl)benzoic acid 2-chloro-3-(hydroxymethyl)-4-(methylsulfonyl)benzoic acid Not in list C9H9ClO5S OC(=O)c1ccc(c(CO)c1Cl)S(C)(=O)=O InChI=1/C9H9ClO5S/c1-16(14,15)7-3-2-5(9(12)13)8(10)6(7)4-11/h2-3,11H,4H2,1H3,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is a metabolite of the substance 2-Chloro-3-(hydroxymethyl)-4-(methylsulfonyl)benzoic acid 2-chloro-3-(hydroxymethyl)-4-(methylsulfonyl)benzoic acid Not in list C9H9ClO5S OC(=O)c1ccc(c(CO)c1Cl)S(C)(=O)=O InChI=1/C9H9ClO5S/c1-16(14,15)7-3-2-5(9(12)13)8(10)6(7)4-11/h2-3,11H,4H2,1H3,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is a metabolite of the substance 2-Chloro-3-(hydroxymethyl)-4-(methylsulfonyl)benzoic acid 2-chloro-3-(hydroxymethyl)-4-(methylsulfonyl)benzoic acid Not in list C9H9ClO5S OC(=O)c1ccc(c(CO)c1Cl)S(C)(=O)=O InChI=1/C9H9ClO5S/c1-16(14,15)7-3-2-5(9(12)13)8(10)6(7)4-11/h2-3,11H,4H2,1H3,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is a metabolite of the substance 2-Chloro-3-(hydroxymethyl)-4-(methylsulfonyl)benzoic acid 2-chloro-3-(hydroxymethyl)-4-(methylsulfonyl)benzoic acid Not in list C9H9ClO5S OC(=O)c1ccc(c(CO)c1Cl)S(C)(=O)=O InChI=1/C9H9ClO5S/c1-16(14,15)7-3-2-5(9(12)13)8(10)6(7)4-11/h2-3,11H,4H2,1H3,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is a metabolite of the substance 2-Chloro-3-(hydroxymethyl)-4-(methylsulfonyl)benzoic acid 2-chloro-3-(hydroxymethyl)-4-(methylsulfonyl)benzoic acid Not in list C9H9ClO5S OC(=O)c1ccc(c(CO)c1Cl)S(C)(=O)=O InChI=1/C9H9ClO5S/c1-16(14,15)7-3-2-5(9(12)13)8(10)6(7)4-11/h2-3,11H,4H2,1H3,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is a metabolite of the substance 2-Chloro-3-(hydroxymethyl)-4-(methylsulfonyl)benzoic acid 2-chloro-3-(hydroxymethyl)-4-(methylsulfonyl)benzoic acid Not in list C9H9ClO5S OC(=O)c1ccc(c(CO)c1Cl)S(C)(=O)=O InChI=1/C9H9ClO5S/c1-16(14,15)7-3-2-5(9(12)13)8(10)6(7)4-11/h2-3,11H,4H2,1H3,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is a metabolite of the substance 2-Chloro-3-(hydroxymethyl)-4-(methylsulfonyl)benzoic acid 2-chloro-3-(hydroxymethyl)-4-(methylsulfonyl)benzoic acid Not in list C9H9ClO5S OC(=O)c1ccc(c(CO)c1Cl)S(C)(=O)=O InChI=1/C9H9ClO5S/c1-16(14,15)7-3-2-5(9(12)13)8(10)6(7)4-11/h2-3,11H,4H2,1H3,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent no treatment without Negative RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is a metabolite of the substance 2-Chloro-3-(hydroxymethyl)-4-(methylsulfonyl)benzoic acid 2-chloro-3-(hydroxymethyl)-4-(methylsulfonyl)benzoic acid Not in list C9H9ClO5S OC(=O)c1ccc(c(CO)c1Cl)S(C)(=O)=O InChI=1/C9H9ClO5S/c1-16(14,15)7-3-2-5(9(12)13)8(10)6(7)4-11/h2-3,11H,4H2,1H3,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent no treatment with Negative RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is a metabolite of the substance 6-(Methylsulfonyl)-5-[(2,2,2-trifluoroethoxy)methyl]-3,4-dihydro-1H-xanthene-1,9(2H)-dione 6-(methylsulfonyl)-5-[(2,2,2-trifluoroethoxy)methyl]-3,4-dihydro-1H-xanthene-1,9(2H)-dione Not in list C17H15F3O6S CS(=O)(=O)c2ccc1C(=O)C=3C(=O)CCCC=3Oc1c2COCC(F)(F)F InChI=1/C17H15F3O6S/c1-27(23,24)13-6-5-9-15(22)14-11(21)3-2-4-12(14)26-16(9)10(13)7-25-8-17(18,19)20/h5-6H,2-4,7-8H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent no treatment with Negative RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is a metabolite of the substance 6-(Methylsulfonyl)-5-[(2,2,2-trifluoroethoxy)methyl]-3,4-dihydro-1H-xanthene-1,9(2H)-dione 6-(methylsulfonyl)-5-[(2,2,2-trifluoroethoxy)methyl]-3,4-dihydro-1H-xanthene-1,9(2H)-dione Not in list C17H15F3O6S CS(=O)(=O)c2ccc1C(=O)C=3C(=O)CCCC=3Oc1c2COCC(F)(F)F InChI=1/C17H15F3O6S/c1-27(23,24)13-6-5-9-15(22)14-11(21)3-2-4-12(14)26-16(9)10(13)7-25-8-17(18,19)20/h5-6H,2-4,7-8H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent no treatment without Negative RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is a metabolite of the substance 6-(Methylsulfonyl)-5-[(2,2,2-trifluoroethoxy)methyl]-3,4-dihydro-1H-xanthene-1,9(2H)-dione 6-(methylsulfonyl)-5-[(2,2,2-trifluoroethoxy)methyl]-3,4-dihydro-1H-xanthene-1,9(2H)-dione Not in list C17H15F3O6S CS(=O)(=O)c2ccc1C(=O)C=3C(=O)CCCC=3Oc1c2COCC(F)(F)F InChI=1/C17H15F3O6S/c1-27(23,24)13-6-5-9-15(22)14-11(21)3-2-4-12(14)26-16(9)10(13)7-25-8-17(18,19)20/h5-6H,2-4,7-8H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent no treatment with Negative RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is a metabolite of the substance 6-(Methylsulfonyl)-5-[(2,2,2-trifluoroethoxy)methyl]-3,4-dihydro-1H-xanthene-1,9(2H)-dione 6-(methylsulfonyl)-5-[(2,2,2-trifluoroethoxy)methyl]-3,4-dihydro-1H-xanthene-1,9(2H)-dione Not in list C17H15F3O6S CS(=O)(=O)c2ccc1C(=O)C=3C(=O)CCCC=3Oc1c2COCC(F)(F)F InChI=1/C17H15F3O6S/c1-27(23,24)13-6-5-9-15(22)14-11(21)3-2-4-12(14)26-16(9)10(13)7-25-8-17(18,19)20/h5-6H,2-4,7-8H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent no treatment with Negative RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is a metabolite of the substance 6-(Methylsulfonyl)-5-[(2,2,2-trifluoroethoxy)methyl]-3,4-dihydro-1H-xanthene-1,9(2H)-dione 6-(methylsulfonyl)-5-[(2,2,2-trifluoroethoxy)methyl]-3,4-dihydro-1H-xanthene-1,9(2H)-dione Not in list C17H15F3O6S CS(=O)(=O)c2ccc1C(=O)C=3C(=O)CCCC=3Oc1c2COCC(F)(F)F InChI=1/C17H15F3O6S/c1-27(23,24)13-6-5-9-15(22)14-11(21)3-2-4-12(14)26-16(9)10(13)7-25-8-17(18,19)20/h5-6H,2-4,7-8H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent no treatment without Negative RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is a metabolite of the substance 6-(Methylsulfonyl)-5-[(2,2,2-trifluoroethoxy)methyl]-3,4-dihydro-1H-xanthene-1,9(2H)-dione 6-(methylsulfonyl)-5-[(2,2,2-trifluoroethoxy)methyl]-3,4-dihydro-1H-xanthene-1,9(2H)-dione Not in list C17H15F3O6S CS(=O)(=O)c2ccc1C(=O)C=3C(=O)CCCC=3Oc1c2COCC(F)(F)F InChI=1/C17H15F3O6S/c1-27(23,24)13-6-5-9-15(22)14-11(21)3-2-4-12(14)26-16(9)10(13)7-25-8-17(18,19)20/h5-6H,2-4,7-8H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent no treatment without Negative RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is a metabolite of the substance 6-(Methylsulfonyl)-5-[(2,2,2-trifluoroethoxy)methyl]-3,4-dihydro-1H-xanthene-1,9(2H)-dione 6-(methylsulfonyl)-5-[(2,2,2-trifluoroethoxy)methyl]-3,4-dihydro-1H-xanthene-1,9(2H)-dione Not in list C17H15F3O6S CS(=O)(=O)c2ccc1C(=O)C=3C(=O)CCCC=3Oc1c2COCC(F)(F)F InChI=1/C17H15F3O6S/c1-27(23,24)13-6-5-9-15(22)14-11(21)3-2-4-12(14)26-16(9)10(13)7-25-8-17(18,19)20/h5-6H,2-4,7-8H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent no treatment without Negative RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is a metabolite of the substance 6-(Methylsulfonyl)-5-[(2,2,2-trifluoroethoxy)methyl]-3,4-dihydro-1H-xanthene-1,9(2H)-dione 6-(methylsulfonyl)-5-[(2,2,2-trifluoroethoxy)methyl]-3,4-dihydro-1H-xanthene-1,9(2H)-dione Not in list C17H15F3O6S CS(=O)(=O)c2ccc1C(=O)C=3C(=O)CCCC=3Oc1c2COCC(F)(F)F InChI=1/C17H15F3O6S/c1-27(23,24)13-6-5-9-15(22)14-11(21)3-2-4-12(14)26-16(9)10(13)7-25-8-17(18,19)20/h5-6H,2-4,7-8H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent no treatment without Negative RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is a metabolite of the substance 6-(Methylsulfonyl)-5-[(2,2,2-trifluoroethoxy)methyl]-3,4-dihydro-1H-xanthene-1,9(2H)-dione 6-(methylsulfonyl)-5-[(2,2,2-trifluoroethoxy)methyl]-3,4-dihydro-1H-xanthene-1,9(2H)-dione Not in list C17H15F3O6S CS(=O)(=O)c2ccc1C(=O)C=3C(=O)CCCC=3Oc1c2COCC(F)(F)F InChI=1/C17H15F3O6S/c1-27(23,24)13-6-5-9-15(22)14-11(21)3-2-4-12(14)26-16(9)10(13)7-25-8-17(18,19)20/h5-6H,2-4,7-8H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent no treatment with Negative RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Tembotrione 608-879-8 335104-84-2 single chemical entity Component is a metabolite of the substance 6-(Methylsulfonyl)-5-[(2,2,2-trifluoroethoxy)methyl]-3,4-dihydro-1H-xanthene-1,9(2H)-dione 6-(methylsulfonyl)-5-[(2,2,2-trifluoroethoxy)methyl]-3,4-dihydro-1H-xanthene-1,9(2H)-dione Not in list C17H15F3O6S CS(=O)(=O)c2ccc1C(=O)C=3C(=O)CCCC=3Oc1c2COCC(F)(F)F InChI=1/C17H15F3O6S/c1-27(23,24)13-6-5-9-15(22)14-11(21)3-2-4-12(14)26-16(9)10(13)7-25-8-17(18,19)20/h5-6H,2-4,7-8H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent no treatment with Negative RMS: Austria Tembotrione 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione 15Mar2013 2013 doi:10.2903/j.efsa.2013.3131
+Fluxapyroxad 907204-31-3 single chemical entity Component is identical to the substance Fluxapyroxad 907204-31-3 3-(Difluoromethyl)-1-methyl-N-[2-(3,4,5-trifluorophenyl)phenyl]pyrazole-4-carboxamide Fluxapyroxad C18H12F5N3O CN1C=C(C(=N1)C(F)F)C(=O)NC2=CC=CC=C2C3=CC(=C(C(=C3)F)F)F InChI=1S/C18H12F5N3O/c1-26-8-11(16(25-26)17(22)23)18(27)24-14-5-3-2-4-10(14)9-6-12(19)15(21)13(20)7-9/h2-8,17H,1H3,(H,24,27) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Fluxapyroxad 907204-31-3 single chemical entity Component is identical to the substance Fluxapyroxad 907204-31-3 3-(Difluoromethyl)-1-methyl-N-[2-(3,4,5-trifluorophenyl)phenyl]pyrazole-4-carboxamide Fluxapyroxad C18H12F5N3O CN1C=C(C(=N1)C(F)F)C(=O)NC2=CC=CC=C2C3=CC(=C(C(=C3)F)F)F InChI=1S/C18H12F5N3O/c1-26-8-11(16(25-26)17(22)23)18(27)24-14-5-3-2-4-10(14)9-6-12(19)15(21)13(20)7-9/h2-8,17H,1H3,(H,24,27) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Fluxapyroxad 907204-31-3 single chemical entity Component is identical to the substance Fluxapyroxad 907204-31-3 3-(Difluoromethyl)-1-methyl-N-[2-(3,4,5-trifluorophenyl)phenyl]pyrazole-4-carboxamide Fluxapyroxad C18H12F5N3O CN1C=C(C(=N1)C(F)F)C(=O)NC2=CC=CC=C2C3=CC(=C(C(=C3)F)F)F InChI=1S/C18H12F5N3O/c1-26-8-11(16(25-26)17(22)23)18(27)24-14-5-3-2-4-10(14)9-6-12(19)15(21)13(20)7-9/h2-8,17H,1H3,(H,24,27) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Fluxapyroxad 907204-31-3 single chemical entity Component is identical to the substance Fluxapyroxad 907204-31-3 3-(Difluoromethyl)-1-methyl-N-[2-(3,4,5-trifluorophenyl)phenyl]pyrazole-4-carboxamide Fluxapyroxad C18H12F5N3O CN1C=C(C(=N1)C(F)F)C(=O)NC2=CC=CC=C2C3=CC(=C(C(=C3)F)F)F InChI=1S/C18H12F5N3O/c1-26-8-11(16(25-26)17(22)23)18(27)24-14-5-3-2-4-10(14)9-6-12(19)15(21)13(20)7-9/h2-8,17H,1H3,(H,24,27) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Fluxapyroxad 907204-31-3 single chemical entity Component is identical to the substance Fluxapyroxad 907204-31-3 3-(Difluoromethyl)-1-methyl-N-[2-(3,4,5-trifluorophenyl)phenyl]pyrazole-4-carboxamide Fluxapyroxad C18H12F5N3O CN1C=C(C(=N1)C(F)F)C(=O)NC2=CC=CC=C2C3=CC(=C(C(=C3)F)F)F InChI=1S/C18H12F5N3O/c1-26-8-11(16(25-26)17(22)23)18(27)24-14-5-3-2-4-10(14)9-6-12(19)15(21)13(20)7-9/h2-8,17H,1H3,(H,24,27) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Fluxapyroxad 907204-31-3 single chemical entity Component is identical to the substance Fluxapyroxad 907204-31-3 3-(Difluoromethyl)-1-methyl-N-[2-(3,4,5-trifluorophenyl)phenyl]pyrazole-4-carboxamide Fluxapyroxad C18H12F5N3O CN1C=C(C(=N1)C(F)F)C(=O)NC2=CC=CC=C2C3=CC(=C(C(=C3)F)F)F InChI=1S/C18H12F5N3O/c1-26-8-11(16(25-26)17(22)23)18(27)24-14-5-3-2-4-10(14)9-6-12(19)15(21)13(20)7-9/h2-8,17H,1H3,(H,24,27) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Fluxapyroxad 907204-31-3 single chemical entity Component is identical to the substance Fluxapyroxad 907204-31-3 3-(Difluoromethyl)-1-methyl-N-[2-(3,4,5-trifluorophenyl)phenyl]pyrazole-4-carboxamide Fluxapyroxad C18H12F5N3O CN1C=C(C(=N1)C(F)F)C(=O)NC2=CC=CC=C2C3=CC(=C(C(=C3)F)F)F InChI=1S/C18H12F5N3O/c1-26-8-11(16(25-26)17(22)23)18(27)24-14-5-3-2-4-10(14)9-6-12(19)15(21)13(20)7-9/h2-8,17H,1H3,(H,24,27) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Fluxapyroxad 907204-31-3 single chemical entity Component is identical to the substance Fluxapyroxad 907204-31-3 3-(Difluoromethyl)-1-methyl-N-[2-(3,4,5-trifluorophenyl)phenyl]pyrazole-4-carboxamide Fluxapyroxad C18H12F5N3O CN1C=C(C(=N1)C(F)F)C(=O)NC2=CC=CC=C2C3=CC(=C(C(=C3)F)F)F InChI=1S/C18H12F5N3O/c1-26-8-11(16(25-26)17(22)23)18(27)24-14-5-3-2-4-10(14)9-6-12(19)15(21)13(20)7-9/h2-8,17H,1H3,(H,24,27) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Fluxapyroxad 907204-31-3 single chemical entity Component is identical to the substance Fluxapyroxad 907204-31-3 3-(Difluoromethyl)-1-methyl-N-[2-(3,4,5-trifluorophenyl)phenyl]pyrazole-4-carboxamide Fluxapyroxad C18H12F5N3O CN1C=C(C(=N1)C(F)F)C(=O)NC2=CC=CC=C2C3=CC(=C(C(=C3)F)F)F InChI=1S/C18H12F5N3O/c1-26-8-11(16(25-26)17(22)23)18(27)24-14-5-3-2-4-10(14)9-6-12(19)15(21)13(20)7-9/h2-8,17H,1H3,(H,24,27) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Fluxapyroxad 907204-31-3 single chemical entity Component is identical to the substance Fluxapyroxad 907204-31-3 3-(Difluoromethyl)-1-methyl-N-[2-(3,4,5-trifluorophenyl)phenyl]pyrazole-4-carboxamide Fluxapyroxad C18H12F5N3O CN1C=C(C(=N1)C(F)F)C(=O)NC2=CC=CC=C2C3=CC(=C(C(=C3)F)F)F InChI=1S/C18H12F5N3O/c1-26-8-11(16(25-26)17(22)23)18(27)24-14-5-3-2-4-10(14)9-6-12(19)15(21)13(20)7-9/h2-8,17H,1H3,(H,24,27) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Fluxapyroxad 907204-31-3 single chemical entity Component is identical to the substance Fluxapyroxad 907204-31-3 3-(Difluoromethyl)-1-methyl-N-[2-(3,4,5-trifluorophenyl)phenyl]pyrazole-4-carboxamide Fluxapyroxad C18H12F5N3O CN1C=C(C(=N1)C(F)F)C(=O)NC2=CC=CC=C2C3=CC(=C(C(=C3)F)F)F InChI=1S/C18H12F5N3O/c1-26-8-11(16(25-26)17(22)23)18(27)24-14-5-3-2-4-10(14)9-6-12(19)15(21)13(20)7-9/h2-8,17H,1H3,(H,24,27) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Fluxapyroxad 907204-31-3 single chemical entity Component is identical to the substance Fluxapyroxad 907204-31-3 3-(Difluoromethyl)-1-methyl-N-[2-(3,4,5-trifluorophenyl)phenyl]pyrazole-4-carboxamide Fluxapyroxad C18H12F5N3O CN1C=C(C(=N1)C(F)F)C(=O)NC2=CC=CC=C2C3=CC(=C(C(=C3)F)F)F InChI=1S/C18H12F5N3O/c1-26-8-11(16(25-26)17(22)23)18(27)24-14-5-3-2-4-10(14)9-6-12(19)15(21)13(20)7-9/h2-8,17H,1H3,(H,24,27) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Fluxapyroxad 907204-31-3 single chemical entity Component is identical to the substance Fluxapyroxad 907204-31-3 3-(Difluoromethyl)-1-methyl-N-[2-(3,4,5-trifluorophenyl)phenyl]pyrazole-4-carboxamide Fluxapyroxad C18H12F5N3O CN1C=C(C(=N1)C(F)F)C(=O)NC2=CC=CC=C2C3=CC(=C(C(=C3)F)F)F InChI=1S/C18H12F5N3O/c1-26-8-11(16(25-26)17(22)23)18(27)24-14-5-3-2-4-10(14)9-6-12(19)15(21)13(20)7-9/h2-8,17H,1H3,(H,24,27) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Fluxapyroxad 907204-31-3 single chemical entity Component is identical to the substance Fluxapyroxad 907204-31-3 3-(Difluoromethyl)-1-methyl-N-[2-(3,4,5-trifluorophenyl)phenyl]pyrazole-4-carboxamide Fluxapyroxad C18H12F5N3O CN1C=C(C(=N1)C(F)F)C(=O)NC2=CC=CC=C2C3=CC(=C(C(=C3)F)F)F InChI=1S/C18H12F5N3O/c1-26-8-11(16(25-26)17(22)23)18(27)24-14-5-3-2-4-10(14)9-6-12(19)15(21)13(20)7-9/h2-8,17H,1H3,(H,24,27) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Fluxapyroxad 907204-31-3 single chemical entity Component is identical to the substance Fluxapyroxad 907204-31-3 3-(Difluoromethyl)-1-methyl-N-[2-(3,4,5-trifluorophenyl)phenyl]pyrazole-4-carboxamide Fluxapyroxad C18H12F5N3O CN1C=C(C(=N1)C(F)F)C(=O)NC2=CC=CC=C2C3=CC(=C(C(=C3)F)F)F InChI=1S/C18H12F5N3O/c1-26-8-11(16(25-26)17(22)23)18(27)24-14-5-3-2-4-10(14)9-6-12(19)15(21)13(20)7-9/h2-8,17H,1H3,(H,24,27) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 5 Male oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect-toxicokinetic investigations RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Fluxapyroxad 907204-31-3 single chemical entity Component is identical to the substance Fluxapyroxad 907204-31-3 3-(Difluoromethyl)-1-methyl-N-[2-(3,4,5-trifluorophenyl)phenyl]pyrazole-4-carboxamide Fluxapyroxad C18H12F5N3O CN1C=C(C(=N1)C(F)F)C(=O)NC2=CC=CC=C2C3=CC(=C(C(=C3)F)F)F InChI=1S/C18H12F5N3O/c1-26-8-11(16(25-26)17(22)23)18(27)24-14-5-3-2-4-10(14)9-6-12(19)15(21)13(20)7-9/h2-8,17H,1H3,(H,24,27) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Wistar 3 Male oral: gavage 14.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Fluxapyroxad 907204-31-3 single chemical entity Component is identical to the substance Fluxapyroxad 907204-31-3 3-(Difluoromethyl)-1-methyl-N-[2-(3,4,5-trifluorophenyl)phenyl]pyrazole-4-carboxamide Fluxapyroxad C18H12F5N3O CN1C=C(C(=N1)C(F)F)C(=O)NC2=CC=CC=C2C3=CC(=C(C(=C3)F)F)F InChI=1S/C18H12F5N3O/c1-26-8-11(16(25-26)17(22)23)18(27)24-14-5-3-2-4-10(14)9-6-12(19)15(21)13(20)7-9/h2-8,17H,1H3,(H,24,27) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Wistar 3 Male oral: gavage 3.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Fluxapyroxad 907204-31-3 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid 176969-34-9 3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid Not in list C6H6F2N2O2 CN1C=C(C(=N1)C(F)F)C(=O)O InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Fluxapyroxad 907204-31-3 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid 176969-34-9 3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid Not in list C6H6F2N2O2 CN1C=C(C(=N1)C(F)F)C(=O)O InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Fluxapyroxad 907204-31-3 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid 176969-34-9 3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid Not in list C6H6F2N2O2 CN1C=C(C(=N1)C(F)F)C(=O)O InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Fluxapyroxad 907204-31-3 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid 176969-34-9 3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid Not in list C6H6F2N2O2 CN1C=C(C(=N1)C(F)F)C(=O)O InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Fluxapyroxad 907204-31-3 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid 176969-34-9 3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid Not in list C6H6F2N2O2 CN1C=C(C(=N1)C(F)F)C(=O)O InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Fluxapyroxad 907204-31-3 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid 176969-34-9 3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid Not in list C6H6F2N2O2 CN1C=C(C(=N1)C(F)F)C(=O)O InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Fluxapyroxad 907204-31-3 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid 176969-34-9 3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid Not in list C6H6F2N2O2 CN1C=C(C(=N1)C(F)F)C(=O)O InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Fluxapyroxad 907204-31-3 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid 176969-34-9 3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid Not in list C6H6F2N2O2 CN1C=C(C(=N1)C(F)F)C(=O)O InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Fluxapyroxad 907204-31-3 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid 176969-34-9 3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid Not in list C6H6F2N2O2 CN1C=C(C(=N1)C(F)F)C(=O)O InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Fluxapyroxad 907204-31-3 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid 176969-34-9 3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid Not in list C6H6F2N2O2 CN1C=C(C(=N1)C(F)F)C(=O)O InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Fluxapyroxad 907204-31-3 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid 176969-34-9 3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid Not in list C6H6F2N2O2 CN1C=C(C(=N1)C(F)F)C(=O)O InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Fluxapyroxad 907204-31-3 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid 176969-34-9 3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid Not in list C6H6F2N2O2 CN1C=C(C(=N1)C(F)F)C(=O)O InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Fluxapyroxad 907204-31-3 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid 176969-34-9 3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid Not in list C6H6F2N2O2 CN1C=C(C(=N1)C(F)F)C(=O)O InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported no data with Negative RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Fluxapyroxad 907204-31-3 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid 176969-34-9 3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid Not in list C6H6F2N2O2 CN1C=C(C(=N1)C(F)F)C(=O)O InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported no data without Negative RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Fluxapyroxad 907204-31-3 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid 176969-34-9 3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid Not in list C6H6F2N2O2 CN1C=C(C(=N1)C(F)F)C(=O)O InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 5 Male oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Fluxapyroxad 907204-31-3 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid 176969-34-9 3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid Not in list C6H6F2N2O2 CN1C=C(C(=N1)C(F)F)C(=O)O InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 5 Male oral: unspecified 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Fluxapyroxad 907204-31-3 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C5H4F2N2O2 FC(F)c1nncc1C(=O)O InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Fluxapyroxad 907204-31-3 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C5H4F2N2O2 FC(F)c1nncc1C(=O)O InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Fluxapyroxad 907204-31-3 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C5H4F2N2O2 FC(F)c1nncc1C(=O)O InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Fluxapyroxad 907204-31-3 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C5H4F2N2O2 FC(F)c1nncc1C(=O)O InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Fluxapyroxad 907204-31-3 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C5H4F2N2O2 FC(F)c1nncc1C(=O)O InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Fluxapyroxad 907204-31-3 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C5H4F2N2O2 FC(F)c1nncc1C(=O)O InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Fluxapyroxad 907204-31-3 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C5H4F2N2O2 FC(F)c1nncc1C(=O)O InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Fluxapyroxad 907204-31-3 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C5H4F2N2O2 FC(F)c1nncc1C(=O)O InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Fluxapyroxad 907204-31-3 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C5H4F2N2O2 FC(F)c1nncc1C(=O)O InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Fluxapyroxad 907204-31-3 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C5H4F2N2O2 FC(F)c1nncc1C(=O)O InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Fluxapyroxad 907204-31-3 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C5H4F2N2O2 FC(F)c1nncc1C(=O)O InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Fluxapyroxad 907204-31-3 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C5H4F2N2O2 FC(F)c1nncc1C(=O)O InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Fluxapyroxad 907204-31-3 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C5H4F2N2O2 FC(F)c1nncc1C(=O)O InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported no data with Negative RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Fluxapyroxad 907204-31-3 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C5H4F2N2O2 FC(F)c1nncc1C(=O)O InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported no data without Negative RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Fluxapyroxad 907204-31-3 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C5H4F2N2O2 FC(F)c1nncc1C(=O)O InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 5 Male oral: unspecified 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect-toxicokinetic investigations RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Fluxapyroxad 907204-31-3 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C5H4F2N2O2 FC(F)c1nncc1C(=O)O InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 5 Male oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect-toxicokinetic investigations RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Fluxapyroxad 907204-31-3 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide 3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide Not in list C23H20F5N3O7 Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Fluxapyroxad 907204-31-3 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide 3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide Not in list C23H20F5N3O7 Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Fluxapyroxad 907204-31-3 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide 3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide Not in list C23H20F5N3O7 Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Fluxapyroxad 907204-31-3 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide 3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide Not in list C23H20F5N3O7 Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Fluxapyroxad 907204-31-3 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide 3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide Not in list C23H20F5N3O7 Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Fluxapyroxad 907204-31-3 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide 3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide Not in list C23H20F5N3O7 Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Fluxapyroxad 907204-31-3 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide 3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide Not in list C23H20F5N3O7 Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Fluxapyroxad 907204-31-3 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide 3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide Not in list C23H20F5N3O7 Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Fluxapyroxad 907204-31-3 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide 3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide Not in list C23H20F5N3O7 Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Fluxapyroxad 907204-31-3 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide 3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide Not in list C23H20F5N3O7 Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Fluxapyroxad 907204-31-3 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide 3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide Not in list C23H20F5N3O7 Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Fluxapyroxad 907204-31-3 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide 3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide Not in list C23H20F5N3O7 Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Fluxapyroxad 907204-31-3 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide 3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide Not in list C23H20F5N3O7 Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported no data without Negative RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Fluxapyroxad 907204-31-3 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide 3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide Not in list C23H20F5N3O7 Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported no data with Negative RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Fluxapyroxad 907204-31-3 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide 3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide Not in list C23H20F5N3O7 Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 5 Male oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect-toxicokinetic investigations RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Fluxapyroxad 907204-31-3 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide 3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide Not in list C23H20F5N3O7 Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 5 Male oral: unspecified 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect-toxicokinetic investigations RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Fluxapyroxad 907204-31-3 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide 3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide Not in list C23H20F5N3O7 Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1 organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Wistar 3 Male oral: unspecified 14.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom BAS 700 F (Fluxapyroxad) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F) 27Jan2012 2012 doi:10.2903/j.efsa.2012.2522
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is identical to the substance Thifensulfuron-methyl 616-673-4 79277-27-3 methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate Thifensulfuron-methyl C12H13N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is identical to the substance Thifensulfuron-methyl 616-673-4 79277-27-3 methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate Thifensulfuron-methyl C12H13N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is identical to the substance Thifensulfuron-methyl 616-673-4 79277-27-3 methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate Thifensulfuron-methyl C12H13N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is identical to the substance Thifensulfuron-methyl 616-673-4 79277-27-3 methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate Thifensulfuron-methyl C12H13N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is identical to the substance Thifensulfuron-methyl 616-673-4 79277-27-3 methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate Thifensulfuron-methyl C12H13N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is identical to the substance Thifensulfuron-methyl 616-673-4 79277-27-3 methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate Thifensulfuron-methyl C12H13N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is identical to the substance Thifensulfuron-methyl 616-673-4 79277-27-3 methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate Thifensulfuron-methyl C12H13N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is identical to the substance Thifensulfuron-methyl 616-673-4 79277-27-3 methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate Thifensulfuron-methyl C12H13N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is identical to the substance Thifensulfuron-methyl 616-673-4 79277-27-3 methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate Thifensulfuron-methyl C12H13N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is identical to the substance Thifensulfuron-methyl 616-673-4 79277-27-3 methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate Thifensulfuron-methyl C12H13N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is identical to the substance Thifensulfuron-methyl 616-673-4 79277-27-3 methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate Thifensulfuron-methyl C12H13N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported no data without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is identical to the substance Thifensulfuron-methyl 616-673-4 79277-27-3 methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate Thifensulfuron-methyl C12H13N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is identical to the substance Thifensulfuron-methyl 616-673-4 79277-27-3 methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate Thifensulfuron-methyl C12H13N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is identical to the substance Thifensulfuron-methyl 616-673-4 79277-27-3 methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate Thifensulfuron-methyl C12H13N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is identical to the substance Thifensulfuron-methyl 616-673-4 79277-27-3 methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate Thifensulfuron-methyl C12H13N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is identical to the substance Thifensulfuron-methyl 616-673-4 79277-27-3 methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate Thifensulfuron-methyl C12H13N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported no data with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is identical to the substance Thifensulfuron-methyl 616-673-4 79277-27-3 methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate Thifensulfuron-methyl C12H13N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is identical to the substance Thifensulfuron-methyl 616-673-4 79277-27-3 methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate Thifensulfuron-methyl C12H13N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is identical to the substance Thifensulfuron-methyl 616-673-4 79277-27-3 methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate Thifensulfuron-methyl C12H13N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is identical to the substance Thifensulfuron-methyl 616-673-4 79277-27-3 methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate Thifensulfuron-methyl C12H13N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is identical to the substance Thifensulfuron-methyl 616-673-4 79277-27-3 methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate Thifensulfuron-methyl C12H13N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is identical to the substance Thifensulfuron-methyl 616-673-4 79277-27-3 methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate Thifensulfuron-methyl C12H13N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is identical to the substance Thifensulfuron-methyl 616-673-4 79277-27-3 methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate Thifensulfuron-methyl C12H13N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is identical to the substance Thifensulfuron-methyl 616-673-4 79277-27-3 methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate Thifensulfuron-methyl C12H13N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is identical to the substance Thifensulfuron-methyl 616-673-4 79277-27-3 methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate Thifensulfuron-methyl C12H13N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is identical to the substance Thifensulfuron-methyl 616-673-4 79277-27-3 methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate Thifensulfuron-methyl C12H13N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is identical to the substance Thifensulfuron-methyl 616-673-4 79277-27-3 methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate Thifensulfuron-methyl C12H13N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is identical to the substance Thifensulfuron-methyl 616-673-4 79277-27-3 methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate Thifensulfuron-methyl C12H13N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is identical to the substance Thifensulfuron-methyl 616-673-4 79277-27-3 methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate Thifensulfuron-methyl C12H13N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is identical to the substance Thifensulfuron-methyl 616-673-4 79277-27-3 methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate Thifensulfuron-methyl C12H13N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is identical to the substance Thifensulfuron-methyl 616-673-4 79277-27-3 methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate Thifensulfuron-methyl C12H13N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is identical to the substance Thifensulfuron-methyl 616-673-4 79277-27-3 methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate Thifensulfuron-methyl C12H13N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is identical to the substance Thifensulfuron-methyl 616-673-4 79277-27-3 methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate Thifensulfuron-methyl C12H13N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is identical to the substance Thifensulfuron-methyl 616-673-4 79277-27-3 methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate Thifensulfuron-methyl C12H13N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Not reported 10 Male/Female oral: unspecified 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is identical to the substance Thifensulfuron-methyl 616-673-4 79277-27-3 methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate Thifensulfuron-methyl C12H13N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Not reported 10 Male/Female oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is identical to the substance Thifensulfuron-methyl 616-673-4 79277-27-3 methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate Thifensulfuron-methyl C12H13N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Not reported 10 Male/Female oral: unspecified 72.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is identical to the substance Thifensulfuron-methyl 616-673-4 79277-27-3 methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate Thifensulfuron-methyl C12H13N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Rat (as animal) Sprague-Dawley 10 Male/Female oral: unspecified 6.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is identical to the substance Thifensulfuron-methyl 616-673-4 79277-27-3 methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate Thifensulfuron-methyl C12H13N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Rat (as animal) Sprague-Dawley 10 Male/Female oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is identical to the substance Thifensulfuron-methyl 616-673-4 79277-27-3 methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate Thifensulfuron-methyl C12H13N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Rat (as animal) Sprague-Dawley 10 Male/Female oral: unspecified 48.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Ambiguous RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Hamster (as animal) Chinese 48 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Hamster (as animal) Chinese 48 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Hamster (as animal) Chinese 48 Male/Female oral: gavage 16.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-sulfamoylthiophene-2-carboxylic acid 59337-97-2 3-sulfamoylthiophene-2-carboxylic acid Not in list C5H5NO4S2 C1=CSC(=C1S(=O)(=O)N)C(=O)O InChI=1S/C5H5NO4S2/c6-12(9,10)3-1-2-11-4(3)5(7)8/h1-2H,(H,7,8)(H2,6,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-sulfamoylthiophene-2-carboxylic acid 59337-97-2 3-sulfamoylthiophene-2-carboxylic acid Not in list C5H5NO4S2 C1=CSC(=C1S(=O)(=O)N)C(=O)O InChI=1S/C5H5NO4S2/c6-12(9,10)3-1-2-11-4(3)5(7)8/h1-2H,(H,7,8)(H2,6,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-sulfamoylthiophene-2-carboxylic acid 59337-97-2 3-sulfamoylthiophene-2-carboxylic acid Not in list C5H5NO4S2 C1=CSC(=C1S(=O)(=O)N)C(=O)O InChI=1S/C5H5NO4S2/c6-12(9,10)3-1-2-11-4(3)5(7)8/h1-2H,(H,7,8)(H2,6,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-sulfamoylthiophene-2-carboxylic acid 59337-97-2 3-sulfamoylthiophene-2-carboxylic acid Not in list C5H5NO4S2 C1=CSC(=C1S(=O)(=O)N)C(=O)O InChI=1S/C5H5NO4S2/c6-12(9,10)3-1-2-11-4(3)5(7)8/h1-2H,(H,7,8)(H2,6,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-sulfamoylthiophene-2-carboxylic acid 59337-97-2 3-sulfamoylthiophene-2-carboxylic acid Not in list C5H5NO4S2 C1=CSC(=C1S(=O)(=O)N)C(=O)O InChI=1S/C5H5NO4S2/c6-12(9,10)3-1-2-11-4(3)5(7)8/h1-2H,(H,7,8)(H2,6,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-sulfamoylthiophene-2-carboxylic acid 59337-97-2 3-sulfamoylthiophene-2-carboxylic acid Not in list C5H5NO4S2 C1=CSC(=C1S(=O)(=O)N)C(=O)O InChI=1S/C5H5NO4S2/c6-12(9,10)3-1-2-11-4(3)5(7)8/h1-2H,(H,7,8)(H2,6,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-sulfamoylthiophene-2-carboxylic acid 59337-97-2 3-sulfamoylthiophene-2-carboxylic acid Not in list C5H5NO4S2 C1=CSC(=C1S(=O)(=O)N)C(=O)O InChI=1S/C5H5NO4S2/c6-12(9,10)3-1-2-11-4(3)5(7)8/h1-2H,(H,7,8)(H2,6,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-sulfamoylthiophene-2-carboxylic acid 59337-97-2 3-sulfamoylthiophene-2-carboxylic acid Not in list C5H5NO4S2 C1=CSC(=C1S(=O)(=O)N)C(=O)O InChI=1S/C5H5NO4S2/c6-12(9,10)3-1-2-11-4(3)5(7)8/h1-2H,(H,7,8)(H2,6,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-sulfamoylthiophene-2-carboxylic acid 59337-97-2 3-sulfamoylthiophene-2-carboxylic acid Not in list C5H5NO4S2 C1=CSC(=C1S(=O)(=O)N)C(=O)O InChI=1S/C5H5NO4S2/c6-12(9,10)3-1-2-11-4(3)5(7)8/h1-2H,(H,7,8)(H2,6,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-sulfamoylthiophene-2-carboxylic acid 59337-97-2 3-sulfamoylthiophene-2-carboxylic acid Not in list C5H5NO4S2 C1=CSC(=C1S(=O)(=O)N)C(=O)O InChI=1S/C5H5NO4S2/c6-12(9,10)3-1-2-11-4(3)5(7)8/h1-2H,(H,7,8)(H2,6,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-sulfamoylthiophene-2-carboxylic acid 59337-97-2 3-sulfamoylthiophene-2-carboxylic acid Not in list C5H5NO4S2 C1=CSC(=C1S(=O)(=O)N)C(=O)O InChI=1S/C5H5NO4S2/c6-12(9,10)3-1-2-11-4(3)5(7)8/h1-2H,(H,7,8)(H2,6,9,10) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-sulfamoylthiophene-2-carboxylic acid 59337-97-2 3-sulfamoylthiophene-2-carboxylic acid Not in list C5H5NO4S2 C1=CSC(=C1S(=O)(=O)N)C(=O)O InChI=1S/C5H5NO4S2/c6-12(9,10)3-1-2-11-4(3)5(7)8/h1-2H,(H,7,8)(H2,6,9,10) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-sulfamoylthiophene-2-carboxylic acid 59337-97-2 3-sulfamoylthiophene-2-carboxylic acid Not in list C5H5NO4S2 C1=CSC(=C1S(=O)(=O)N)C(=O)O InChI=1S/C5H5NO4S2/c6-12(9,10)3-1-2-11-4(3)5(7)8/h1-2H,(H,7,8)(H2,6,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-sulfamoylthiophene-2-carboxylic acid 59337-97-2 3-sulfamoylthiophene-2-carboxylic acid Not in list C5H5NO4S2 C1=CSC(=C1S(=O)(=O)N)C(=O)O InChI=1S/C5H5NO4S2/c6-12(9,10)3-1-2-11-4(3)5(7)8/h1-2H,(H,7,8)(H2,6,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-sulfamoylthiophene-2-carboxylic acid 59337-97-2 3-sulfamoylthiophene-2-carboxylic acid Not in list C5H5NO4S2 C1=CSC(=C1S(=O)(=O)N)C(=O)O InChI=1S/C5H5NO4S2/c6-12(9,10)3-1-2-11-4(3)5(7)8/h1-2H,(H,7,8)(H2,6,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-sulfamoylthiophene-2-carboxylic acid 59337-97-2 3-sulfamoylthiophene-2-carboxylic acid Not in list C5H5NO4S2 C1=CSC(=C1S(=O)(=O)N)C(=O)O InChI=1S/C5H5NO4S2/c6-12(9,10)3-1-2-11-4(3)5(7)8/h1-2H,(H,7,8)(H2,6,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-sulfamoylthiophene-2-carboxylic acid 59337-97-2 3-sulfamoylthiophene-2-carboxylic acid Not in list C5H5NO4S2 C1=CSC(=C1S(=O)(=O)N)C(=O)O InChI=1S/C5H5NO4S2/c6-12(9,10)3-1-2-11-4(3)5(7)8/h1-2H,(H,7,8)(H2,6,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-sulfamoylthiophene-2-carboxylic acid 59337-97-2 3-sulfamoylthiophene-2-carboxylic acid Not in list C5H5NO4S2 C1=CSC(=C1S(=O)(=O)N)C(=O)O InChI=1S/C5H5NO4S2/c6-12(9,10)3-1-2-11-4(3)5(7)8/h1-2H,(H,7,8)(H2,6,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-sulfamoylthiophene-2-carboxylic acid 59337-97-2 3-sulfamoylthiophene-2-carboxylic acid Not in list C5H5NO4S2 C1=CSC(=C1S(=O)(=O)N)C(=O)O InChI=1S/C5H5NO4S2/c6-12(9,10)3-1-2-11-4(3)5(7)8/h1-2H,(H,7,8)(H2,6,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-sulfamoylthiophene-2-carboxylic acid 59337-97-2 3-sulfamoylthiophene-2-carboxylic acid Not in list C5H5NO4S2 C1=CSC(=C1S(=O)(=O)N)C(=O)O InChI=1S/C5H5NO4S2/c6-12(9,10)3-1-2-11-4(3)5(7)8/h1-2H,(H,7,8)(H2,6,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-sulfamoylthiophene-2-carboxylic acid 59337-97-2 3-sulfamoylthiophene-2-carboxylic acid Not in list C5H5NO4S2 C1=CSC(=C1S(=O)(=O)N)C(=O)O InChI=1S/C5H5NO4S2/c6-12(9,10)3-1-2-11-4(3)5(7)8/h1-2H,(H,7,8)(H2,6,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-sulfamoylthiophene-2-carboxylic acid 59337-97-2 3-sulfamoylthiophene-2-carboxylic acid Not in list C5H5NO4S2 C1=CSC(=C1S(=O)(=O)N)C(=O)O InChI=1S/C5H5NO4S2/c6-12(9,10)3-1-2-11-4(3)5(7)8/h1-2H,(H,7,8)(H2,6,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-sulfamoylthiophene-2-carboxylic acid 59337-97-2 3-sulfamoylthiophene-2-carboxylic acid Not in list C5H5NO4S2 C1=CSC(=C1S(=O)(=O)N)C(=O)O InChI=1S/C5H5NO4S2/c6-12(9,10)3-1-2-11-4(3)5(7)8/h1-2H,(H,7,8)(H2,6,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-sulfamoylthiophene-2-carboxylic acid 59337-97-2 3-sulfamoylthiophene-2-carboxylic acid Not in list C5H5NO4S2 C1=CSC(=C1S(=O)(=O)N)C(=O)O InChI=1S/C5H5NO4S2/c6-12(9,10)3-1-2-11-4(3)5(7)8/h1-2H,(H,7,8)(H2,6,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-sulfamoylthiophene-2-carboxylic acid 59337-97-2 3-sulfamoylthiophene-2-carboxylic acid Not in list C5H5NO4S2 C1=CSC(=C1S(=O)(=O)N)C(=O)O InChI=1S/C5H5NO4S2/c6-12(9,10)3-1-2-11-4(3)5(7)8/h1-2H,(H,7,8)(H2,6,9,10) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported no data without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-sulfamoylthiophene-2-carboxylic acid 59337-97-2 3-sulfamoylthiophene-2-carboxylic acid Not in list C5H5NO4S2 C1=CSC(=C1S(=O)(=O)N)C(=O)O InChI=1S/C5H5NO4S2/c6-12(9,10)3-1-2-11-4(3)5(7)8/h1-2H,(H,7,8)(H2,6,9,10) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported no data with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-sulfamoylthiophene-2-carboxylic acid 59337-97-2 3-sulfamoylthiophene-2-carboxylic acid Not in list C5H5NO4S2 C1=CSC(=C1S(=O)(=O)N)C(=O)O InChI=1S/C5H5NO4S2/c6-12(9,10)3-1-2-11-4(3)5(7)8/h1-2H,(H,7,8)(H2,6,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data without Negative no information RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-sulfamoylthiophene-2-carboxylic acid 59337-97-2 3-sulfamoylthiophene-2-carboxylic acid Not in list C5H5NO4S2 C1=CSC(=C1S(=O)(=O)N)C(=O)O InChI=1S/C5H5NO4S2/c6-12(9,10)3-1-2-11-4(3)5(7)8/h1-2H,(H,7,8)(H2,6,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data with Negative no information RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid 616-675-5 79277-67-1 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylic acid Not in list C11H11N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)O InChI=1S/C11H11N5O6S2/c1-5-12-9(15-11(13-5)22-2)14-10(19)16-24(20,21)6-3-4-23-7(6)8(17)18/h3-4H,1-2H3,(H,17,18)(H2,12,13,14,15,16,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid 616-675-5 79277-67-1 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylic acid Not in list C11H11N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)O InChI=1S/C11H11N5O6S2/c1-5-12-9(15-11(13-5)22-2)14-10(19)16-24(20,21)6-3-4-23-7(6)8(17)18/h3-4H,1-2H3,(H,17,18)(H2,12,13,14,15,16,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid 616-675-5 79277-67-1 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylic acid Not in list C11H11N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)O InChI=1S/C11H11N5O6S2/c1-5-12-9(15-11(13-5)22-2)14-10(19)16-24(20,21)6-3-4-23-7(6)8(17)18/h3-4H,1-2H3,(H,17,18)(H2,12,13,14,15,16,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid 616-675-5 79277-67-1 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylic acid Not in list C11H11N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)O InChI=1S/C11H11N5O6S2/c1-5-12-9(15-11(13-5)22-2)14-10(19)16-24(20,21)6-3-4-23-7(6)8(17)18/h3-4H,1-2H3,(H,17,18)(H2,12,13,14,15,16,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid 616-675-5 79277-67-1 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylic acid Not in list C11H11N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)O InChI=1S/C11H11N5O6S2/c1-5-12-9(15-11(13-5)22-2)14-10(19)16-24(20,21)6-3-4-23-7(6)8(17)18/h3-4H,1-2H3,(H,17,18)(H2,12,13,14,15,16,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid 616-675-5 79277-67-1 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylic acid Not in list C11H11N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)O InChI=1S/C11H11N5O6S2/c1-5-12-9(15-11(13-5)22-2)14-10(19)16-24(20,21)6-3-4-23-7(6)8(17)18/h3-4H,1-2H3,(H,17,18)(H2,12,13,14,15,16,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid 616-675-5 79277-67-1 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylic acid Not in list C11H11N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)O InChI=1S/C11H11N5O6S2/c1-5-12-9(15-11(13-5)22-2)14-10(19)16-24(20,21)6-3-4-23-7(6)8(17)18/h3-4H,1-2H3,(H,17,18)(H2,12,13,14,15,16,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid 616-675-5 79277-67-1 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylic acid Not in list C11H11N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)O InChI=1S/C11H11N5O6S2/c1-5-12-9(15-11(13-5)22-2)14-10(19)16-24(20,21)6-3-4-23-7(6)8(17)18/h3-4H,1-2H3,(H,17,18)(H2,12,13,14,15,16,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid 616-675-5 79277-67-1 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylic acid Not in list C11H11N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)O InChI=1S/C11H11N5O6S2/c1-5-12-9(15-11(13-5)22-2)14-10(19)16-24(20,21)6-3-4-23-7(6)8(17)18/h3-4H,1-2H3,(H,17,18)(H2,12,13,14,15,16,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid 616-675-5 79277-67-1 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylic acid Not in list C11H11N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)O InChI=1S/C11H11N5O6S2/c1-5-12-9(15-11(13-5)22-2)14-10(19)16-24(20,21)6-3-4-23-7(6)8(17)18/h3-4H,1-2H3,(H,17,18)(H2,12,13,14,15,16,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid 616-675-5 79277-67-1 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylic acid Not in list C11H11N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)O InChI=1S/C11H11N5O6S2/c1-5-12-9(15-11(13-5)22-2)14-10(19)16-24(20,21)6-3-4-23-7(6)8(17)18/h3-4H,1-2H3,(H,17,18)(H2,12,13,14,15,16,19) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid 616-675-5 79277-67-1 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylic acid Not in list C11H11N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)O InChI=1S/C11H11N5O6S2/c1-5-12-9(15-11(13-5)22-2)14-10(19)16-24(20,21)6-3-4-23-7(6)8(17)18/h3-4H,1-2H3,(H,17,18)(H2,12,13,14,15,16,19) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid 616-675-5 79277-67-1 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylic acid Not in list C11H11N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)O InChI=1S/C11H11N5O6S2/c1-5-12-9(15-11(13-5)22-2)14-10(19)16-24(20,21)6-3-4-23-7(6)8(17)18/h3-4H,1-2H3,(H,17,18)(H2,12,13,14,15,16,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid 616-675-5 79277-67-1 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylic acid Not in list C11H11N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)O InChI=1S/C11H11N5O6S2/c1-5-12-9(15-11(13-5)22-2)14-10(19)16-24(20,21)6-3-4-23-7(6)8(17)18/h3-4H,1-2H3,(H,17,18)(H2,12,13,14,15,16,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid 616-675-5 79277-67-1 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylic acid Not in list C11H11N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)O InChI=1S/C11H11N5O6S2/c1-5-12-9(15-11(13-5)22-2)14-10(19)16-24(20,21)6-3-4-23-7(6)8(17)18/h3-4H,1-2H3,(H,17,18)(H2,12,13,14,15,16,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid 616-675-5 79277-67-1 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylic acid Not in list C11H11N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)O InChI=1S/C11H11N5O6S2/c1-5-12-9(15-11(13-5)22-2)14-10(19)16-24(20,21)6-3-4-23-7(6)8(17)18/h3-4H,1-2H3,(H,17,18)(H2,12,13,14,15,16,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid 616-675-5 79277-67-1 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylic acid Not in list C11H11N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)O InChI=1S/C11H11N5O6S2/c1-5-12-9(15-11(13-5)22-2)14-10(19)16-24(20,21)6-3-4-23-7(6)8(17)18/h3-4H,1-2H3,(H,17,18)(H2,12,13,14,15,16,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid 616-675-5 79277-67-1 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylic acid Not in list C11H11N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)O InChI=1S/C11H11N5O6S2/c1-5-12-9(15-11(13-5)22-2)14-10(19)16-24(20,21)6-3-4-23-7(6)8(17)18/h3-4H,1-2H3,(H,17,18)(H2,12,13,14,15,16,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid 616-675-5 79277-67-1 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylic acid Not in list C11H11N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)O InChI=1S/C11H11N5O6S2/c1-5-12-9(15-11(13-5)22-2)14-10(19)16-24(20,21)6-3-4-23-7(6)8(17)18/h3-4H,1-2H3,(H,17,18)(H2,12,13,14,15,16,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid 616-675-5 79277-67-1 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylic acid Not in list C11H11N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)O InChI=1S/C11H11N5O6S2/c1-5-12-9(15-11(13-5)22-2)14-10(19)16-24(20,21)6-3-4-23-7(6)8(17)18/h3-4H,1-2H3,(H,17,18)(H2,12,13,14,15,16,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid 616-675-5 79277-67-1 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylic acid Not in list C11H11N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)O InChI=1S/C11H11N5O6S2/c1-5-12-9(15-11(13-5)22-2)14-10(19)16-24(20,21)6-3-4-23-7(6)8(17)18/h3-4H,1-2H3,(H,17,18)(H2,12,13,14,15,16,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid 616-675-5 79277-67-1 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylic acid Not in list C11H11N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)O InChI=1S/C11H11N5O6S2/c1-5-12-9(15-11(13-5)22-2)14-10(19)16-24(20,21)6-3-4-23-7(6)8(17)18/h3-4H,1-2H3,(H,17,18)(H2,12,13,14,15,16,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid 616-675-5 79277-67-1 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylic acid Not in list C11H11N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)O InChI=1S/C11H11N5O6S2/c1-5-12-9(15-11(13-5)22-2)14-10(19)16-24(20,21)6-3-4-23-7(6)8(17)18/h3-4H,1-2H3,(H,17,18)(H2,12,13,14,15,16,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid 616-675-5 79277-67-1 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylic acid Not in list C11H11N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)O InChI=1S/C11H11N5O6S2/c1-5-12-9(15-11(13-5)22-2)14-10(19)16-24(20,21)6-3-4-23-7(6)8(17)18/h3-4H,1-2H3,(H,17,18)(H2,12,13,14,15,16,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid 616-675-5 79277-67-1 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylic acid Not in list C11H11N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)O InChI=1S/C11H11N5O6S2/c1-5-12-9(15-11(13-5)22-2)14-10(19)16-24(20,21)6-3-4-23-7(6)8(17)18/h3-4H,1-2H3,(H,17,18)(H2,12,13,14,15,16,19) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian cell micronucleus test in vitro According to OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid 616-675-5 79277-67-1 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylic acid Not in list C11H11N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)O InChI=1S/C11H11N5O6S2/c1-5-12-9(15-11(13-5)22-2)14-10(19)16-24(20,21)6-3-4-23-7(6)8(17)18/h3-4H,1-2H3,(H,17,18)(H2,12,13,14,15,16,19) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian cell micronucleus test in vitro According to OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 1-(4-methoxy-6-methyl-1,3,5-triazine-2-yl)urea 1-(4-acetyl-6-methyl-1,3,5-triazin-2-yl)urea Not in list C7H9N5O2 O=C(N)Nc1nc(C)nc(n1)C(C)=O InChI=1/C7H9N5O2/c1-3(13)5-9-4(2)10-7(11-5)12-6(8)14/h1-2H3,(H3,8,9,10,11,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 1-(4-methoxy-6-methyl-1,3,5-triazine-2-yl)urea 1-(4-acetyl-6-methyl-1,3,5-triazin-2-yl)urea Not in list C7H9N5O2 O=C(N)Nc1nc(C)nc(n1)C(C)=O InChI=1/C7H9N5O2/c1-3(13)5-9-4(2)10-7(11-5)12-6(8)14/h1-2H3,(H3,8,9,10,11,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 1-(4-methoxy-6-methyl-1,3,5-triazine-2-yl)urea 1-(4-acetyl-6-methyl-1,3,5-triazin-2-yl)urea Not in list C7H9N5O2 O=C(N)Nc1nc(C)nc(n1)C(C)=O InChI=1/C7H9N5O2/c1-3(13)5-9-4(2)10-7(11-5)12-6(8)14/h1-2H3,(H3,8,9,10,11,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 1-(4-methoxy-6-methyl-1,3,5-triazine-2-yl)urea 1-(4-acetyl-6-methyl-1,3,5-triazin-2-yl)urea Not in list C7H9N5O2 O=C(N)Nc1nc(C)nc(n1)C(C)=O InChI=1/C7H9N5O2/c1-3(13)5-9-4(2)10-7(11-5)12-6(8)14/h1-2H3,(H3,8,9,10,11,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 1-(4-methoxy-6-methyl-1,3,5-triazine-2-yl)urea 1-(4-acetyl-6-methyl-1,3,5-triazin-2-yl)urea Not in list C7H9N5O2 O=C(N)Nc1nc(C)nc(n1)C(C)=O InChI=1/C7H9N5O2/c1-3(13)5-9-4(2)10-7(11-5)12-6(8)14/h1-2H3,(H3,8,9,10,11,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 1-(4-methoxy-6-methyl-1,3,5-triazine-2-yl)urea 1-(4-acetyl-6-methyl-1,3,5-triazin-2-yl)urea Not in list C7H9N5O2 O=C(N)Nc1nc(C)nc(n1)C(C)=O InChI=1/C7H9N5O2/c1-3(13)5-9-4(2)10-7(11-5)12-6(8)14/h1-2H3,(H3,8,9,10,11,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 1-(4-methoxy-6-methyl-1,3,5-triazine-2-yl)urea 1-(4-acetyl-6-methyl-1,3,5-triazin-2-yl)urea Not in list C7H9N5O2 O=C(N)Nc1nc(C)nc(n1)C(C)=O InChI=1/C7H9N5O2/c1-3(13)5-9-4(2)10-7(11-5)12-6(8)14/h1-2H3,(H3,8,9,10,11,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 1-(4-methoxy-6-methyl-1,3,5-triazine-2-yl)urea 1-(4-acetyl-6-methyl-1,3,5-triazin-2-yl)urea Not in list C7H9N5O2 O=C(N)Nc1nc(C)nc(n1)C(C)=O InChI=1/C7H9N5O2/c1-3(13)5-9-4(2)10-7(11-5)12-6(8)14/h1-2H3,(H3,8,9,10,11,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 1-(4-methoxy-6-methyl-1,3,5-triazine-2-yl)urea 1-(4-acetyl-6-methyl-1,3,5-triazin-2-yl)urea Not in list C7H9N5O2 O=C(N)Nc1nc(C)nc(n1)C(C)=O InChI=1/C7H9N5O2/c1-3(13)5-9-4(2)10-7(11-5)12-6(8)14/h1-2H3,(H3,8,9,10,11,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 1-(4-methoxy-6-methyl-1,3,5-triazine-2-yl)urea 1-(4-acetyl-6-methyl-1,3,5-triazin-2-yl)urea Not in list C7H9N5O2 O=C(N)Nc1nc(C)nc(n1)C(C)=O InChI=1/C7H9N5O2/c1-3(13)5-9-4(2)10-7(11-5)12-6(8)14/h1-2H3,(H3,8,9,10,11,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 1-(4-methoxy-6-methyl-1,3,5-triazine-2-yl)urea 1-(4-acetyl-6-methyl-1,3,5-triazin-2-yl)urea Not in list C7H9N5O2 O=C(N)Nc1nc(C)nc(n1)C(C)=O InChI=1/C7H9N5O2/c1-3(13)5-9-4(2)10-7(11-5)12-6(8)14/h1-2H3,(H3,8,9,10,11,12,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 1-(4-methoxy-6-methyl-1,3,5-triazine-2-yl)urea 1-(4-acetyl-6-methyl-1,3,5-triazin-2-yl)urea Not in list C7H9N5O2 O=C(N)Nc1nc(C)nc(n1)C(C)=O InChI=1/C7H9N5O2/c1-3(13)5-9-4(2)10-7(11-5)12-6(8)14/h1-2H3,(H3,8,9,10,11,12,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 1-(4-methoxy-6-methyl-1,3,5-triazine-2-yl)urea 1-(4-acetyl-6-methyl-1,3,5-triazin-2-yl)urea Not in list C7H9N5O2 O=C(N)Nc1nc(C)nc(n1)C(C)=O InChI=1/C7H9N5O2/c1-3(13)5-9-4(2)10-7(11-5)12-6(8)14/h1-2H3,(H3,8,9,10,11,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 1-(4-methoxy-6-methyl-1,3,5-triazine-2-yl)urea 1-(4-acetyl-6-methyl-1,3,5-triazin-2-yl)urea Not in list C7H9N5O2 O=C(N)Nc1nc(C)nc(n1)C(C)=O InChI=1/C7H9N5O2/c1-3(13)5-9-4(2)10-7(11-5)12-6(8)14/h1-2H3,(H3,8,9,10,11,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance thieno[2,3-d][1,2]thiazol-3(2H)-one 1,1-dioxide thieno[2,3-d]isothiazol-3(2H)-one 1,1-dioxide Not in list C5H3NO3S2 O=S2(=O)NC(=O)c1sccc12 InChI=1/C5H3NO3S2/c7-5-4-3(1-2-10-4)11(8,9)6-5/h1-2H,(H,6,7) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance thieno[2,3-d][1,2]thiazol-3(2H)-one 1,1-dioxide thieno[2,3-d]isothiazol-3(2H)-one 1,1-dioxide Not in list C5H3NO3S2 O=S2(=O)NC(=O)c1sccc12 InChI=1/C5H3NO3S2/c7-5-4-3(1-2-10-4)11(8,9)6-5/h1-2H,(H,6,7) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance thieno[2,3-d][1,2]thiazol-3(2H)-one 1,1-dioxide thieno[2,3-d]isothiazol-3(2H)-one 1,1-dioxide Not in list C5H3NO3S2 O=S2(=O)NC(=O)c1sccc12 InChI=1/C5H3NO3S2/c7-5-4-3(1-2-10-4)11(8,9)6-5/h1-2H,(H,6,7) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance thieno[2,3-d][1,2]thiazol-3(2H)-one 1,1-dioxide thieno[2,3-d]isothiazol-3(2H)-one 1,1-dioxide Not in list C5H3NO3S2 O=S2(=O)NC(=O)c1sccc12 InChI=1/C5H3NO3S2/c7-5-4-3(1-2-10-4)11(8,9)6-5/h1-2H,(H,6,7) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance thieno[2,3-d][1,2]thiazol-3(2H)-one 1,1-dioxide thieno[2,3-d]isothiazol-3(2H)-one 1,1-dioxide Not in list C5H3NO3S2 O=S2(=O)NC(=O)c1sccc12 InChI=1/C5H3NO3S2/c7-5-4-3(1-2-10-4)11(8,9)6-5/h1-2H,(H,6,7) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance thieno[2,3-d][1,2]thiazol-3(2H)-one 1,1-dioxide thieno[2,3-d]isothiazol-3(2H)-one 1,1-dioxide Not in list C5H3NO3S2 O=S2(=O)NC(=O)c1sccc12 InChI=1/C5H3NO3S2/c7-5-4-3(1-2-10-4)11(8,9)6-5/h1-2H,(H,6,7) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance thieno[2,3-d][1,2]thiazol-3(2H)-one 1,1-dioxide thieno[2,3-d]isothiazol-3(2H)-one 1,1-dioxide Not in list C5H3NO3S2 O=S2(=O)NC(=O)c1sccc12 InChI=1/C5H3NO3S2/c7-5-4-3(1-2-10-4)11(8,9)6-5/h1-2H,(H,6,7) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance thieno[2,3-d][1,2]thiazol-3(2H)-one 1,1-dioxide thieno[2,3-d]isothiazol-3(2H)-one 1,1-dioxide Not in list C5H3NO3S2 O=S2(=O)NC(=O)c1sccc12 InChI=1/C5H3NO3S2/c7-5-4-3(1-2-10-4)11(8,9)6-5/h1-2H,(H,6,7) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance thieno[2,3-d][1,2]thiazol-3(2H)-one 1,1-dioxide thieno[2,3-d]isothiazol-3(2H)-one 1,1-dioxide Not in list C5H3NO3S2 O=S2(=O)NC(=O)c1sccc12 InChI=1/C5H3NO3S2/c7-5-4-3(1-2-10-4)11(8,9)6-5/h1-2H,(H,6,7) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance thieno[2,3-d][1,2]thiazol-3(2H)-one 1,1-dioxide thieno[2,3-d]isothiazol-3(2H)-one 1,1-dioxide Not in list C5H3NO3S2 O=S2(=O)NC(=O)c1sccc12 InChI=1/C5H3NO3S2/c7-5-4-3(1-2-10-4)11(8,9)6-5/h1-2H,(H,6,7) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance thieno[2,3-d][1,2]thiazol-3(2H)-one 1,1-dioxide thieno[2,3-d]isothiazol-3(2H)-one 1,1-dioxide Not in list C5H3NO3S2 O=S2(=O)NC(=O)c1sccc12 InChI=1/C5H3NO3S2/c7-5-4-3(1-2-10-4)11(8,9)6-5/h1-2H,(H,6,7) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance thieno[2,3-d][1,2]thiazol-3(2H)-one 1,1-dioxide thieno[2,3-d]isothiazol-3(2H)-one 1,1-dioxide Not in list C5H3NO3S2 O=S2(=O)NC(=O)c1sccc12 InChI=1/C5H3NO3S2/c7-5-4-3(1-2-10-4)11(8,9)6-5/h1-2H,(H,6,7) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance thieno[2,3-d][1,2]thiazol-3(2H)-one 1,1-dioxide thieno[2,3-d]isothiazol-3(2H)-one 1,1-dioxide Not in list C5H3NO3S2 O=S2(=O)NC(=O)c1sccc12 InChI=1/C5H3NO3S2/c7-5-4-3(1-2-10-4)11(8,9)6-5/h1-2H,(H,6,7) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance thieno[2,3-d][1,2]thiazol-3(2H)-one 1,1-dioxide thieno[2,3-d]isothiazol-3(2H)-one 1,1-dioxide Not in list C5H3NO3S2 O=S2(=O)NC(=O)c1sccc12 InChI=1/C5H3NO3S2/c7-5-4-3(1-2-10-4)11(8,9)6-5/h1-2H,(H,6,7) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance thieno[2,3-d][1,2]thiazol-3(2H)-one 1,1-dioxide thieno[2,3-d]isothiazol-3(2H)-one 1,1-dioxide Not in list C5H3NO3S2 O=S2(=O)NC(=O)c1sccc12 InChI=1/C5H3NO3S2/c7-5-4-3(1-2-10-4)11(8,9)6-5/h1-2H,(H,6,7) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 28 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance thieno[2,3-d][1,2]thiazol-3(2H)-one 1,1-dioxide thieno[2,3-d]isothiazol-3(2H)-one 1,1-dioxide Not in list C5H3NO3S2 O=S2(=O)NC(=O)c1sccc12 InChI=1/C5H3NO3S2/c7-5-4-3(1-2-10-4)11(8,9)6-5/h1-2H,(H,6,7) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 28 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-{[(4-hydroxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid 3-{[(4-hydroxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid Not in list C10H9N5O6S2 OC(=O)c1sccc1S(=O)(=O)NC(=O)Nc2nc(C)nc(O)n2 InChI=1/C10H9N5O6S2/c1-4-11-8(13-9(18)12-4)14-10(19)15-23(20,21)5-2-3-22-6(5)7(16)17/h2-3H,1H3,(H,16,17)(H3,11,12,13,14,15,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-{[(4-hydroxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid 3-{[(4-hydroxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid Not in list C10H9N5O6S2 OC(=O)c1sccc1S(=O)(=O)NC(=O)Nc2nc(C)nc(O)n2 InChI=1/C10H9N5O6S2/c1-4-11-8(13-9(18)12-4)14-10(19)15-23(20,21)5-2-3-22-6(5)7(16)17/h2-3H,1H3,(H,16,17)(H3,11,12,13,14,15,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-{[(4-hydroxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid 3-{[(4-hydroxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid Not in list C10H9N5O6S2 OC(=O)c1sccc1S(=O)(=O)NC(=O)Nc2nc(C)nc(O)n2 InChI=1/C10H9N5O6S2/c1-4-11-8(13-9(18)12-4)14-10(19)15-23(20,21)5-2-3-22-6(5)7(16)17/h2-3H,1H3,(H,16,17)(H3,11,12,13,14,15,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-{[(4-hydroxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid 3-{[(4-hydroxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid Not in list C10H9N5O6S2 OC(=O)c1sccc1S(=O)(=O)NC(=O)Nc2nc(C)nc(O)n2 InChI=1/C10H9N5O6S2/c1-4-11-8(13-9(18)12-4)14-10(19)15-23(20,21)5-2-3-22-6(5)7(16)17/h2-3H,1H3,(H,16,17)(H3,11,12,13,14,15,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-{[(4-hydroxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid 3-{[(4-hydroxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid Not in list C10H9N5O6S2 OC(=O)c1sccc1S(=O)(=O)NC(=O)Nc2nc(C)nc(O)n2 InChI=1/C10H9N5O6S2/c1-4-11-8(13-9(18)12-4)14-10(19)15-23(20,21)5-2-3-22-6(5)7(16)17/h2-3H,1H3,(H,16,17)(H3,11,12,13,14,15,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-{[(4-hydroxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid 3-{[(4-hydroxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid Not in list C10H9N5O6S2 OC(=O)c1sccc1S(=O)(=O)NC(=O)Nc2nc(C)nc(O)n2 InChI=1/C10H9N5O6S2/c1-4-11-8(13-9(18)12-4)14-10(19)15-23(20,21)5-2-3-22-6(5)7(16)17/h2-3H,1H3,(H,16,17)(H3,11,12,13,14,15,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-{[(4-hydroxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid 3-{[(4-hydroxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid Not in list C10H9N5O6S2 OC(=O)c1sccc1S(=O)(=O)NC(=O)Nc2nc(C)nc(O)n2 InChI=1/C10H9N5O6S2/c1-4-11-8(13-9(18)12-4)14-10(19)15-23(20,21)5-2-3-22-6(5)7(16)17/h2-3H,1H3,(H,16,17)(H3,11,12,13,14,15,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-{[(4-hydroxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid 3-{[(4-hydroxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid Not in list C10H9N5O6S2 OC(=O)c1sccc1S(=O)(=O)NC(=O)Nc2nc(C)nc(O)n2 InChI=1/C10H9N5O6S2/c1-4-11-8(13-9(18)12-4)14-10(19)15-23(20,21)5-2-3-22-6(5)7(16)17/h2-3H,1H3,(H,16,17)(H3,11,12,13,14,15,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-{[(4-hydroxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid 3-{[(4-hydroxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid Not in list C10H9N5O6S2 OC(=O)c1sccc1S(=O)(=O)NC(=O)Nc2nc(C)nc(O)n2 InChI=1/C10H9N5O6S2/c1-4-11-8(13-9(18)12-4)14-10(19)15-23(20,21)5-2-3-22-6(5)7(16)17/h2-3H,1H3,(H,16,17)(H3,11,12,13,14,15,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-{[(4-hydroxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid 3-{[(4-hydroxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid Not in list C10H9N5O6S2 OC(=O)c1sccc1S(=O)(=O)NC(=O)Nc2nc(C)nc(O)n2 InChI=1/C10H9N5O6S2/c1-4-11-8(13-9(18)12-4)14-10(19)15-23(20,21)5-2-3-22-6(5)7(16)17/h2-3H,1H3,(H,16,17)(H3,11,12,13,14,15,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-{[(4-hydroxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid 3-{[(4-hydroxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid Not in list C10H9N5O6S2 OC(=O)c1sccc1S(=O)(=O)NC(=O)Nc2nc(C)nc(O)n2 InChI=1/C10H9N5O6S2/c1-4-11-8(13-9(18)12-4)14-10(19)15-23(20,21)5-2-3-22-6(5)7(16)17/h2-3H,1H3,(H,16,17)(H3,11,12,13,14,15,18,19) organic compound Other Other chromosome aberration in vitro mammalian cell micronucleus test in vitro According to OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance 3-{[(4-hydroxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid 3-{[(4-hydroxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid Not in list C10H9N5O6S2 OC(=O)c1sccc1S(=O)(=O)NC(=O)Nc2nc(C)nc(O)n2 InChI=1/C10H9N5O6S2/c1-4-11-8(13-9(18)12-4)14-10(19)15-23(20,21)5-2-3-22-6(5)7(16)17/h2-3H,1H3,(H,16,17)(H3,11,12,13,14,15,18,19) organic compound Other Other chromosome aberration in vitro mammalian cell micronucleus test in vitro According to OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance methyl 3-sulfamoylthiophene-2-carboxylate methyl 3-sulfamoylthiophene-2-carboxylate Not in list C6H7NO4S2 O=S(N)(=O)c1ccsc1C(=O)OC InChI=1/C6H7NO4S2/c1-11-6(8)5-4(2-3-12-5)13(7,9)10/h2-3H,1H3,(H2,7,9,10) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance methyl 3-sulfamoylthiophene-2-carboxylate methyl 3-sulfamoylthiophene-2-carboxylate Not in list C6H7NO4S2 O=S(N)(=O)c1ccsc1C(=O)OC InChI=1/C6H7NO4S2/c1-11-6(8)5-4(2-3-12-5)13(7,9)10/h2-3H,1H3,(H2,7,9,10) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance methyl 3-sulfamoylthiophene-2-carboxylate methyl 3-sulfamoylthiophene-2-carboxylate Not in list C6H7NO4S2 O=S(N)(=O)c1ccsc1C(=O)OC InChI=1/C6H7NO4S2/c1-11-6(8)5-4(2-3-12-5)13(7,9)10/h2-3H,1H3,(H2,7,9,10) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance methyl 3-sulfamoylthiophene-2-carboxylate methyl 3-sulfamoylthiophene-2-carboxylate Not in list C6H7NO4S2 O=S(N)(=O)c1ccsc1C(=O)OC InChI=1/C6H7NO4S2/c1-11-6(8)5-4(2-3-12-5)13(7,9)10/h2-3H,1H3,(H2,7,9,10) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance methyl 3-sulfamoylthiophene-2-carboxylate methyl 3-sulfamoylthiophene-2-carboxylate Not in list C6H7NO4S2 O=S(N)(=O)c1ccsc1C(=O)OC InChI=1/C6H7NO4S2/c1-11-6(8)5-4(2-3-12-5)13(7,9)10/h2-3H,1H3,(H2,7,9,10) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance methyl 3-sulfamoylthiophene-2-carboxylate methyl 3-sulfamoylthiophene-2-carboxylate Not in list C6H7NO4S2 O=S(N)(=O)c1ccsc1C(=O)OC InChI=1/C6H7NO4S2/c1-11-6(8)5-4(2-3-12-5)13(7,9)10/h2-3H,1H3,(H2,7,9,10) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance methyl 3-sulfamoylthiophene-2-carboxylate methyl 3-sulfamoylthiophene-2-carboxylate Not in list C6H7NO4S2 O=S(N)(=O)c1ccsc1C(=O)OC InChI=1/C6H7NO4S2/c1-11-6(8)5-4(2-3-12-5)13(7,9)10/h2-3H,1H3,(H2,7,9,10) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance methyl 3-sulfamoylthiophene-2-carboxylate methyl 3-sulfamoylthiophene-2-carboxylate Not in list C6H7NO4S2 O=S(N)(=O)c1ccsc1C(=O)OC InChI=1/C6H7NO4S2/c1-11-6(8)5-4(2-3-12-5)13(7,9)10/h2-3H,1H3,(H2,7,9,10) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance methyl 3-sulfamoylthiophene-2-carboxylate methyl 3-sulfamoylthiophene-2-carboxylate Not in list C6H7NO4S2 O=S(N)(=O)c1ccsc1C(=O)OC InChI=1/C6H7NO4S2/c1-11-6(8)5-4(2-3-12-5)13(7,9)10/h2-3H,1H3,(H2,7,9,10) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance methyl 3-sulfamoylthiophene-2-carboxylate methyl 3-sulfamoylthiophene-2-carboxylate Not in list C6H7NO4S2 O=S(N)(=O)c1ccsc1C(=O)OC InChI=1/C6H7NO4S2/c1-11-6(8)5-4(2-3-12-5)13(7,9)10/h2-3H,1H3,(H2,7,9,10) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is identical to the substance Thiamethoxam 428-650-4 153719-23-4 (NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3, 5-oxadiazinan-4-ylidene]nitramide Thiamethoxam C8H10ClN5O3S CN\1COCN(/C1=N/[N+](=O)[O-])CC2=CN=C(S2)Cl InChI=1S/C8H10ClN5O3S/c1-12-4-17-5-13(8(12)11-14(15)16)3-6-2-10-7(9)18-6/h2H,3-5H2,1H3/b11-8+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Spain Thiamethoxam 2001 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is identical to the substance Thiamethoxam 428-650-4 153719-23-4 (NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3, 5-oxadiazinan-4-ylidene]nitramide Thiamethoxam C8H10ClN5O3S CN\1COCN(/C1=N/[N+](=O)[O-])CC2=CN=C(S2)Cl InChI=1S/C8H10ClN5O3S/c1-12-4-17-5-13(8(12)11-14(15)16)3-6-2-10-7(9)18-6/h2H,3-5H2,1H3/b11-8+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Spain Thiamethoxam 2001 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is identical to the substance Thiamethoxam 428-650-4 153719-23-4 (NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3, 5-oxadiazinan-4-ylidene]nitramide Thiamethoxam C8H10ClN5O3S CN\1COCN(/C1=N/[N+](=O)[O-])CC2=CN=C(S2)Cl InChI=1S/C8H10ClN5O3S/c1-12-4-17-5-13(8(12)11-14(15)16)3-6-2-10-7(9)18-6/h2H,3-5H2,1H3/b11-8+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Spain Thiamethoxam 2001 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is identical to the substance Thiamethoxam 428-650-4 153719-23-4 (NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3, 5-oxadiazinan-4-ylidene]nitramide Thiamethoxam C8H10ClN5O3S CN\1COCN(/C1=N/[N+](=O)[O-])CC2=CN=C(S2)Cl InChI=1S/C8H10ClN5O3S/c1-12-4-17-5-13(8(12)11-14(15)16)3-6-2-10-7(9)18-6/h2H,3-5H2,1H3/b11-8+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Spain Thiamethoxam 2001 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is identical to the substance Thiamethoxam 428-650-4 153719-23-4 (NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3, 5-oxadiazinan-4-ylidene]nitramide Thiamethoxam C8H10ClN5O3S CN\1COCN(/C1=N/[N+](=O)[O-])CC2=CN=C(S2)Cl InChI=1S/C8H10ClN5O3S/c1-12-4-17-5-13(8(12)11-14(15)16)3-6-2-10-7(9)18-6/h2H,3-5H2,1H3/b11-8+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Spain Thiamethoxam 2001 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is identical to the substance Thiamethoxam 428-650-4 153719-23-4 (NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3, 5-oxadiazinan-4-ylidene]nitramide Thiamethoxam C8H10ClN5O3S CN\1COCN(/C1=N/[N+](=O)[O-])CC2=CN=C(S2)Cl InChI=1S/C8H10ClN5O3S/c1-12-4-17-5-13(8(12)11-14(15)16)3-6-2-10-7(9)18-6/h2H,3-5H2,1H3/b11-8+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Spain Thiamethoxam 2001 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is identical to the substance Thiamethoxam 428-650-4 153719-23-4 (NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3, 5-oxadiazinan-4-ylidene]nitramide Thiamethoxam C8H10ClN5O3S CN\1COCN(/C1=N/[N+](=O)[O-])CC2=CN=C(S2)Cl InChI=1S/C8H10ClN5O3S/c1-12-4-17-5-13(8(12)11-14(15)16)3-6-2-10-7(9)18-6/h2H,3-5H2,1H3/b11-8+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Spain Thiamethoxam 2001 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is identical to the substance Thiamethoxam 428-650-4 153719-23-4 (NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3, 5-oxadiazinan-4-ylidene]nitramide Thiamethoxam C8H10ClN5O3S CN\1COCN(/C1=N/[N+](=O)[O-])CC2=CN=C(S2)Cl InChI=1S/C8H10ClN5O3S/c1-12-4-17-5-13(8(12)11-14(15)16)3-6-2-10-7(9)18-6/h2H,3-5H2,1H3/b11-8+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Spain Thiamethoxam 2001 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is identical to the substance Thiamethoxam 428-650-4 153719-23-4 (NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3, 5-oxadiazinan-4-ylidene]nitramide Thiamethoxam C8H10ClN5O3S CN\1COCN(/C1=N/[N+](=O)[O-])CC2=CN=C(S2)Cl InChI=1S/C8H10ClN5O3S/c1-12-4-17-5-13(8(12)11-14(15)16)3-6-2-10-7(9)18-6/h2H,3-5H2,1H3/b11-8+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Spain Thiamethoxam 2001 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is identical to the substance Thiamethoxam 428-650-4 153719-23-4 (NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3, 5-oxadiazinan-4-ylidene]nitramide Thiamethoxam C8H10ClN5O3S CN\1COCN(/C1=N/[N+](=O)[O-])CC2=CN=C(S2)Cl InChI=1S/C8H10ClN5O3S/c1-12-4-17-5-13(8(12)11-14(15)16)3-6-2-10-7(9)18-6/h2H,3-5H2,1H3/b11-8+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Spain Thiamethoxam 2001 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is identical to the substance Thiamethoxam 428-650-4 153719-23-4 (NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3, 5-oxadiazinan-4-ylidene]nitramide Thiamethoxam C8H10ClN5O3S CN\1COCN(/C1=N/[N+](=O)[O-])CC2=CN=C(S2)Cl InChI=1S/C8H10ClN5O3S/c1-12-4-17-5-13(8(12)11-14(15)16)3-6-2-10-7(9)18-6/h2H,3-5H2,1H3/b11-8+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Spain Thiamethoxam 2001 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is identical to the substance Thiamethoxam 428-650-4 153719-23-4 (NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3, 5-oxadiazinan-4-ylidene]nitramide Thiamethoxam C8H10ClN5O3S CN\1COCN(/C1=N/[N+](=O)[O-])CC2=CN=C(S2)Cl InChI=1S/C8H10ClN5O3S/c1-12-4-17-5-13(8(12)11-14(15)16)3-6-2-10-7(9)18-6/h2H,3-5H2,1H3/b11-8+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Spain Thiamethoxam 2001 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is identical to the substance Thiamethoxam 428-650-4 153719-23-4 (NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3, 5-oxadiazinan-4-ylidene]nitramide Thiamethoxam C8H10ClN5O3S CN\1COCN(/C1=N/[N+](=O)[O-])CC2=CN=C(S2)Cl InChI=1S/C8H10ClN5O3S/c1-12-4-17-5-13(8(12)11-14(15)16)3-6-2-10-7(9)18-6/h2H,3-5H2,1H3/b11-8+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Spain Thiamethoxam 2001 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is identical to the substance Thiamethoxam 428-650-4 153719-23-4 (NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3, 5-oxadiazinan-4-ylidene]nitramide Thiamethoxam C8H10ClN5O3S CN\1COCN(/C1=N/[N+](=O)[O-])CC2=CN=C(S2)Cl InChI=1S/C8H10ClN5O3S/c1-12-4-17-5-13(8(12)11-14(15)16)3-6-2-10-7(9)18-6/h2H,3-5H2,1H3/b11-8+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Spain Thiamethoxam 2001 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is identical to the substance Thiamethoxam 428-650-4 153719-23-4 (NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3, 5-oxadiazinan-4-ylidene]nitramide Thiamethoxam C8H10ClN5O3S CN\1COCN(/C1=N/[N+](=O)[O-])CC2=CN=C(S2)Cl InChI=1S/C8H10ClN5O3S/c1-12-4-17-5-13(8(12)11-14(15)16)3-6-2-10-7(9)18-6/h2H,3-5H2,1H3/b11-8+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Spain Thiamethoxam 2001 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is identical to the substance Thiamethoxam 428-650-4 153719-23-4 (NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3, 5-oxadiazinan-4-ylidene]nitramide Thiamethoxam C8H10ClN5O3S CN\1COCN(/C1=N/[N+](=O)[O-])CC2=CN=C(S2)Cl InChI=1S/C8H10ClN5O3S/c1-12-4-17-5-13(8(12)11-14(15)16)3-6-2-10-7(9)18-6/h2H,3-5H2,1H3/b11-8+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Spain Thiamethoxam 2001 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is identical to the substance Thiamethoxam 428-650-4 153719-23-4 (NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3, 5-oxadiazinan-4-ylidene]nitramide Thiamethoxam C8H10ClN5O3S CN\1COCN(/C1=N/[N+](=O)[O-])CC2=CN=C(S2)Cl InChI=1S/C8H10ClN5O3S/c1-12-4-17-5-13(8(12)11-14(15)16)3-6-2-10-7(9)18-6/h2H,3-5H2,1H3/b11-8+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Spain Thiamethoxam 2001 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is identical to the substance Thiamethoxam 428-650-4 153719-23-4 (NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3, 5-oxadiazinan-4-ylidene]nitramide Thiamethoxam C8H10ClN5O3S CN\1COCN(/C1=N/[N+](=O)[O-])CC2=CN=C(S2)Cl InChI=1S/C8H10ClN5O3S/c1-12-4-17-5-13(8(12)11-14(15)16)3-6-2-10-7(9)18-6/h2H,3-5H2,1H3/b11-8+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: Spain Thiamethoxam 2001 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is identical to the substance Thiamethoxam 428-650-4 153719-23-4 (NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3, 5-oxadiazinan-4-ylidene]nitramide Thiamethoxam C8H10ClN5O3S CN\1COCN(/C1=N/[N+](=O)[O-])CC2=CN=C(S2)Cl InChI=1S/C8H10ClN5O3S/c1-12-4-17-5-13(8(12)11-14(15)16)3-6-2-10-7(9)18-6/h2H,3-5H2,1H3/b11-8+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: Spain Thiamethoxam 2001 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is identical to the substance Thiamethoxam 428-650-4 153719-23-4 (NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3, 5-oxadiazinan-4-ylidene]nitramide Thiamethoxam C8H10ClN5O3S CN\1COCN(/C1=N/[N+](=O)[O-])CC2=CN=C(S2)Cl InChI=1S/C8H10ClN5O3S/c1-12-4-17-5-13(8(12)11-14(15)16)3-6-2-10-7(9)18-6/h2H,3-5H2,1H3/b11-8+ organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Spain Thiamethoxam 2001 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is identical to the substance Thiamethoxam 428-650-4 153719-23-4 (NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3, 5-oxadiazinan-4-ylidene]nitramide Thiamethoxam C8H10ClN5O3S CN\1COCN(/C1=N/[N+](=O)[O-])CC2=CN=C(S2)Cl InChI=1S/C8H10ClN5O3S/c1-12-4-17-5-13(8(12)11-14(15)16)3-6-2-10-7(9)18-6/h2H,3-5H2,1H3/b11-8+ organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Spain Thiamethoxam 2001 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is identical to the substance Thiamethoxam 428-650-4 153719-23-4 (NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3, 5-oxadiazinan-4-ylidene]nitramide Thiamethoxam C8H10ClN5O3S CN\1COCN(/C1=N/[N+](=O)[O-])CC2=CN=C(S2)Cl InChI=1S/C8H10ClN5O3S/c1-12-4-17-5-13(8(12)11-14(15)16)3-6-2-10-7(9)18-6/h2H,3-5H2,1H3/b11-8+ organic compound PubChem isomeric SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Spain Thiamethoxam 2001 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is identical to the substance Thiamethoxam 428-650-4 153719-23-4 (NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3, 5-oxadiazinan-4-ylidene]nitramide Thiamethoxam C8H10ClN5O3S CN\1COCN(/C1=N/[N+](=O)[O-])CC2=CN=C(S2)Cl InChI=1S/C8H10ClN5O3S/c1-12-4-17-5-13(8(12)11-14(15)16)3-6-2-10-7(9)18-6/h2H,3-5H2,1H3/b11-8+ organic compound PubChem isomeric SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable House mouse (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Spain Thiamethoxam 2001 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is identical to the substance Thiamethoxam 428-650-4 153719-23-4 (NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3, 5-oxadiazinan-4-ylidene]nitramide Thiamethoxam C8H10ClN5O3S CN\1COCN(/C1=N/[N+](=O)[O-])CC2=CN=C(S2)Cl InChI=1S/C8H10ClN5O3S/c1-12-4-17-5-13(8(12)11-14(15)16)3-6-2-10-7(9)18-6/h2H,3-5H2,1H3/b11-8+ organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Tif:MAGf(SPF) 5 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Spain Thiamethoxam 2001 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is identical to the substance Thiamethoxam 428-650-4 153719-23-4 (NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3, 5-oxadiazinan-4-ylidene]nitramide Thiamethoxam C8H10ClN5O3S CN\1COCN(/C1=N/[N+](=O)[O-])CC2=CN=C(S2)Cl InChI=1S/C8H10ClN5O3S/c1-12-4-17-5-13(8(12)11-14(15)16)3-6-2-10-7(9)18-6/h2H,3-5H2,1H3/b11-8+ organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Tif:MAGf(SPF) 5 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Spain Thiamethoxam 2001 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is identical to the substance Thiamethoxam 428-650-4 153719-23-4 (NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3, 5-oxadiazinan-4-ylidene]nitramide Thiamethoxam C8H10ClN5O3S CN\1COCN(/C1=N/[N+](=O)[O-])CC2=CN=C(S2)Cl InChI=1S/C8H10ClN5O3S/c1-12-4-17-5-13(8(12)11-14(15)16)3-6-2-10-7(9)18-6/h2H,3-5H2,1H3/b11-8+ organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Tif:MAGf(SPF) 5 Male/Female oral: gavage 16.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Spain Thiamethoxam 2001 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is a metabolite of the substance Clothianidin 433-460-1 210880-92-5 1-[(2-chloro-1,3-thiazol-5-yl)methyl]-2-methyl-3-nitroguanidine Clothianidin C6H8ClN5O2S CN=C(NCC1=CN=C(S1)Cl)N[N+](=O)[O-] InChI=1S/C6H8ClN5O2S/c1-8-6(11-12(13)14)10-3-4-2-9-5(7)15-4/h2H,3H2,1H3,(H2,8,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Spain Thiamethoxam 2001 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is a metabolite of the substance Clothianidin 433-460-1 210880-92-5 1-[(2-chloro-1,3-thiazol-5-yl)methyl]-2-methyl-3-nitroguanidine Clothianidin C6H8ClN5O2S CN=C(NCC1=CN=C(S1)Cl)N[N+](=O)[O-] InChI=1S/C6H8ClN5O2S/c1-8-6(11-12(13)14)10-3-4-2-9-5(7)15-4/h2H,3H2,1H3,(H2,8,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Spain Thiamethoxam 2001 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is a metabolite of the substance Clothianidin 433-460-1 210880-92-5 1-[(2-chloro-1,3-thiazol-5-yl)methyl]-2-methyl-3-nitroguanidine Clothianidin C6H8ClN5O2S CN=C(NCC1=CN=C(S1)Cl)N[N+](=O)[O-] InChI=1S/C6H8ClN5O2S/c1-8-6(11-12(13)14)10-3-4-2-9-5(7)15-4/h2H,3H2,1H3,(H2,8,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Spain Thiamethoxam 2001 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is a metabolite of the substance Clothianidin 433-460-1 210880-92-5 1-[(2-chloro-1,3-thiazol-5-yl)methyl]-2-methyl-3-nitroguanidine Clothianidin C6H8ClN5O2S CN=C(NCC1=CN=C(S1)Cl)N[N+](=O)[O-] InChI=1S/C6H8ClN5O2S/c1-8-6(11-12(13)14)10-3-4-2-9-5(7)15-4/h2H,3H2,1H3,(H2,8,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Spain Thiamethoxam 2001 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is a metabolite of the substance Clothianidin 433-460-1 210880-92-5 1-[(2-chloro-1,3-thiazol-5-yl)methyl]-2-methyl-3-nitroguanidine Clothianidin C6H8ClN5O2S CN=C(NCC1=CN=C(S1)Cl)N[N+](=O)[O-] InChI=1S/C6H8ClN5O2S/c1-8-6(11-12(13)14)10-3-4-2-9-5(7)15-4/h2H,3H2,1H3,(H2,8,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Spain Thiamethoxam 2001 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is a metabolite of the substance Clothianidin 433-460-1 210880-92-5 1-[(2-chloro-1,3-thiazol-5-yl)methyl]-2-methyl-3-nitroguanidine Clothianidin C6H8ClN5O2S CN=C(NCC1=CN=C(S1)Cl)N[N+](=O)[O-] InChI=1S/C6H8ClN5O2S/c1-8-6(11-12(13)14)10-3-4-2-9-5(7)15-4/h2H,3H2,1H3,(H2,8,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Spain Thiamethoxam 2001 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is a metabolite of the substance Clothianidin 433-460-1 210880-92-5 1-[(2-chloro-1,3-thiazol-5-yl)methyl]-2-methyl-3-nitroguanidine Clothianidin C6H8ClN5O2S CN=C(NCC1=CN=C(S1)Cl)N[N+](=O)[O-] InChI=1S/C6H8ClN5O2S/c1-8-6(11-12(13)14)10-3-4-2-9-5(7)15-4/h2H,3H2,1H3,(H2,8,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Spain Thiamethoxam 2001 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is a metabolite of the substance Clothianidin 433-460-1 210880-92-5 1-[(2-chloro-1,3-thiazol-5-yl)methyl]-2-methyl-3-nitroguanidine Clothianidin C6H8ClN5O2S CN=C(NCC1=CN=C(S1)Cl)N[N+](=O)[O-] InChI=1S/C6H8ClN5O2S/c1-8-6(11-12(13)14)10-3-4-2-9-5(7)15-4/h2H,3H2,1H3,(H2,8,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Spain Thiamethoxam 2001 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is a metabolite of the substance Clothianidin 433-460-1 210880-92-5 1-[(2-chloro-1,3-thiazol-5-yl)methyl]-2-methyl-3-nitroguanidine Clothianidin C6H8ClN5O2S CN=C(NCC1=CN=C(S1)Cl)N[N+](=O)[O-] InChI=1S/C6H8ClN5O2S/c1-8-6(11-12(13)14)10-3-4-2-9-5(7)15-4/h2H,3H2,1H3,(H2,8,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Spain Thiamethoxam 2001 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is a metabolite of the substance Clothianidin 433-460-1 210880-92-5 1-[(2-chloro-1,3-thiazol-5-yl)methyl]-2-methyl-3-nitroguanidine Clothianidin C6H8ClN5O2S CN=C(NCC1=CN=C(S1)Cl)N[N+](=O)[O-] InChI=1S/C6H8ClN5O2S/c1-8-6(11-12(13)14)10-3-4-2-9-5(7)15-4/h2H,3H2,1H3,(H2,8,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Spain Thiamethoxam 2001 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is a metabolite of the substance Clothianidin 433-460-1 210880-92-5 1-[(2-chloro-1,3-thiazol-5-yl)methyl]-2-methyl-3-nitroguanidine Clothianidin C6H8ClN5O2S CN=C(NCC1=CN=C(S1)Cl)N[N+](=O)[O-] InChI=1S/C6H8ClN5O2S/c1-8-6(11-12(13)14)10-3-4-2-9-5(7)15-4/h2H,3H2,1H3,(H2,8,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Spain Thiamethoxam 2001 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is a metabolite of the substance Clothianidin 433-460-1 210880-92-5 1-[(2-chloro-1,3-thiazol-5-yl)methyl]-2-methyl-3-nitroguanidine Clothianidin C6H8ClN5O2S CN=C(NCC1=CN=C(S1)Cl)N[N+](=O)[O-] InChI=1S/C6H8ClN5O2S/c1-8-6(11-12(13)14)10-3-4-2-9-5(7)15-4/h2H,3H2,1H3,(H2,8,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Spain Thiamethoxam 2001 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is a metabolite of the substance 3-(2-chlorothiazol-5-ylmethyl)-5-methyl-[1,3,5]oxadiazinan-4-ylideneamin 3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3,5-oxadiazinan-4-imine Not in list C8H11ClN4OS Clc2ncc(CN1COCN(C)C1=N)s2 InChI=1/C8H11ClN4OS/c1-12-4-14-5-13(8(12)10)3-6-2-11-7(9)15-6/h2,10H,3-5H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Spain Thiamethoxam 2001 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is a metabolite of the substance 3-(2-chlorothiazol-5-ylmethyl)-5-methyl-[1,3,5]oxadiazinan-4-ylideneamin 3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3,5-oxadiazinan-4-imine Not in list C8H11ClN4OS Clc2ncc(CN1COCN(C)C1=N)s2 InChI=1/C8H11ClN4OS/c1-12-4-14-5-13(8(12)10)3-6-2-11-7(9)15-6/h2,10H,3-5H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Spain Thiamethoxam 2001 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is a metabolite of the substance 3-(2-chlorothiazol-5-ylmethyl)-5-methyl-[1,3,5]oxadiazinan-4-ylideneamin 3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3,5-oxadiazinan-4-imine Not in list C8H11ClN4OS Clc2ncc(CN1COCN(C)C1=N)s2 InChI=1/C8H11ClN4OS/c1-12-4-14-5-13(8(12)10)3-6-2-11-7(9)15-6/h2,10H,3-5H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Spain Thiamethoxam 2001 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is a metabolite of the substance 3-(2-chlorothiazol-5-ylmethyl)-5-methyl-[1,3,5]oxadiazinan-4-ylideneamin 3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3,5-oxadiazinan-4-imine Not in list C8H11ClN4OS Clc2ncc(CN1COCN(C)C1=N)s2 InChI=1/C8H11ClN4OS/c1-12-4-14-5-13(8(12)10)3-6-2-11-7(9)15-6/h2,10H,3-5H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Spain Thiamethoxam 2001 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is a metabolite of the substance 3-(2-chlorothiazol-5-ylmethyl)-5-methyl-[1,3,5]oxadiazinan-4-ylideneamin 3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3,5-oxadiazinan-4-imine Not in list C8H11ClN4OS Clc2ncc(CN1COCN(C)C1=N)s2 InChI=1/C8H11ClN4OS/c1-12-4-14-5-13(8(12)10)3-6-2-11-7(9)15-6/h2,10H,3-5H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Spain Thiamethoxam 2001 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is a metabolite of the substance 3-(2-chlorothiazol-5-ylmethyl)-5-methyl-[1,3,5]oxadiazinan-4-ylideneamin 3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3,5-oxadiazinan-4-imine Not in list C8H11ClN4OS Clc2ncc(CN1COCN(C)C1=N)s2 InChI=1/C8H11ClN4OS/c1-12-4-14-5-13(8(12)10)3-6-2-11-7(9)15-6/h2,10H,3-5H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Spain Thiamethoxam 2001 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is a metabolite of the substance 3-(2-chlorothiazol-5-ylmethyl)-5-methyl-[1,3,5]oxadiazinan-4-ylideneamin 3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3,5-oxadiazinan-4-imine Not in list C8H11ClN4OS Clc2ncc(CN1COCN(C)C1=N)s2 InChI=1/C8H11ClN4OS/c1-12-4-14-5-13(8(12)10)3-6-2-11-7(9)15-6/h2,10H,3-5H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Spain Thiamethoxam 2001 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is a metabolite of the substance 3-(2-chlorothiazol-5-ylmethyl)-5-methyl-[1,3,5]oxadiazinan-4-ylideneamin 3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3,5-oxadiazinan-4-imine Not in list C8H11ClN4OS Clc2ncc(CN1COCN(C)C1=N)s2 InChI=1/C8H11ClN4OS/c1-12-4-14-5-13(8(12)10)3-6-2-11-7(9)15-6/h2,10H,3-5H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Spain Thiamethoxam 2001 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is a metabolite of the substance 3-(2-chlorothiazol-5-ylmethyl)-5-methyl-[1,3,5]oxadiazinan-4-ylideneamin 3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3,5-oxadiazinan-4-imine Not in list C8H11ClN4OS Clc2ncc(CN1COCN(C)C1=N)s2 InChI=1/C8H11ClN4OS/c1-12-4-14-5-13(8(12)10)3-6-2-11-7(9)15-6/h2,10H,3-5H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Spain Thiamethoxam 2001 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is a metabolite of the substance 3-(2-chlorothiazol-5-ylmethyl)-5-methyl-[1,3,5]oxadiazinan-4-ylideneamin 3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3,5-oxadiazinan-4-imine Not in list C8H11ClN4OS Clc2ncc(CN1COCN(C)C1=N)s2 InChI=1/C8H11ClN4OS/c1-12-4-14-5-13(8(12)10)3-6-2-11-7(9)15-6/h2,10H,3-5H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Spain Thiamethoxam 2001 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is a metabolite of the substance 3-(2-chlorothiazol-5-ylmethyl)-5-methyl-[1,3,5]oxadiazinan-4-ylideneamin 3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3,5-oxadiazinan-4-imine Not in list C8H11ClN4OS Clc2ncc(CN1COCN(C)C1=N)s2 InChI=1/C8H11ClN4OS/c1-12-4-14-5-13(8(12)10)3-6-2-11-7(9)15-6/h2,10H,3-5H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Spain Thiamethoxam 2001 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is a metabolite of the substance 3-(2-chlorothiazol-5-ylmethyl)-5-methyl-[1,3,5]oxadiazinan-4-ylideneamin 3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3,5-oxadiazinan-4-imine Not in list C8H11ClN4OS Clc2ncc(CN1COCN(C)C1=N)s2 InChI=1/C8H11ClN4OS/c1-12-4-14-5-13(8(12)10)3-6-2-11-7(9)15-6/h2,10H,3-5H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Spain Thiamethoxam 2001 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is a metabolite of the substance NOA 459602 Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Spain Thiamethoxam (Addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is a metabolite of the substance NOA 459602 Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Spain Thiamethoxam (Addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is a metabolite of the substance NOA 459602 Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Spain Thiamethoxam (Addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is a metabolite of the substance NOA 459602 Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported no data without Negative RMS: Spain Thiamethoxam (Addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is a metabolite of the substance NOA 459602 Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Spain Thiamethoxam (Addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is a metabolite of the substance NOA 459602 Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Spain Thiamethoxam (Addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is a metabolite of the substance NOA 459602 Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Spain Thiamethoxam (Addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is a metabolite of the substance NOA 459602 Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported no data with Negative RMS: Spain Thiamethoxam (Addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is a metabolite of the substance NOA 459602 Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Spain Thiamethoxam (Addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is a metabolite of the substance NOA 459602 Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Spain Thiamethoxam (Addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is a metabolite of the substance NOA 459602 Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: Spain Thiamethoxam (Addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is a metabolite of the substance NOA 459602 Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: Spain Thiamethoxam (Addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is a metabolite of the substance NOA 459602 Not in list organic no structure gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data with Negative no information RMS: Spain Thiamethoxam (Addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is a metabolite of the substance NOA 459602 Not in list organic no structure gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data without Negative no information RMS: Spain Thiamethoxam (Addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is a metabolite of the substance NOA 459602 Not in list organic no structure chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported no data with Negative RMS: Spain Thiamethoxam (Addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is a metabolite of the substance NOA 459602 Not in list organic no structure chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported no data without Positive RMS: Spain Thiamethoxam (Addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is a metabolite of the substance NOA 459602 Not in list organic no structure chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI Male oral: gavage 24.0000000000 h no data not applicable Negative no evidence RMS: Spain Thiamethoxam (Addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is a metabolite of the substance NOA 459602 Not in list organic no structure chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI Male oral: gavage 48.0000000000 h no data not applicable Negative no evidence RMS: Spain Thiamethoxam (Addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is a metabolite of the substance NOA 459602 Not in list organic no structure DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Sprague-Dawley Male oral: gavage 2.0000000000 h no data not applicable Negative RMS: Spain Thiamethoxam (Addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Thiamethoxam 428-650-4 153719-23-4 single chemical entity Component is a metabolite of the substance NOA 459602 Not in list organic no structure DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Sprague-Dawley Male oral: gavage 16.0000000000 h no data not applicable Negative RMS: Spain Thiamethoxam (Addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam 16Jan2013 2013 doi:10.2903/j.efsa.2013.3067
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation mouse spot test in vivo Equivalent or similar to OECD Guideline 484 (Genetic Toxicology: Mouse Spot Test) No data Acceptable House mouse (as animal) Not reported No data Not reported no data not applicable Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Salmonella typhimurium (as organism) Not reported Not reported no data not applicable Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation other in vivo No guideline available Not reported Not applicable Acceptable Rat (as animal) Not reported subcutaneous no data not applicable Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation other in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) Not reported subcutaneous no data not applicable Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other chromosome aberration other in vitro No guideline available Not reported Not applicable Acceptable Saccharomyces cerevisiae (as organism) Not reported Not reported no data no data Positive RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other chromosome aberration other in vitro No guideline available Not reported Not applicable Acceptable Hamster (as animal) Not reported Not reported no data no data Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No data Acceptable House mouse (as animal) Not reported No data Not reported no data not applicable Positive RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable House mouse (as animal) Not reported No data Not reported no data not applicable Positive RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is a metabolite of the substance 2-aminobenzimidazole 213-280-6 934-32-7 1H-benzimidazol-2-amine Not in list C7H7N3 C1=CC=C2C(=C1)NC(=N2)N InChI=1S/C7H7N3/c8-7-9-5-3-1-2-4-6(5)10-7/h1-4H,(H3,8,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is a metabolite of the substance 2-aminobenzimidazole 213-280-6 934-32-7 1H-benzimidazol-2-amine Not in list C7H7N3 C1=CC=C2C(=C1)NC(=N2)N InChI=1S/C7H7N3/c8-7-9-5-3-1-2-4-6(5)10-7/h1-4H,(H3,8,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is a metabolite of the substance 2-aminobenzimidazole 213-280-6 934-32-7 1H-benzimidazol-2-amine Not in list C7H7N3 C1=CC=C2C(=C1)NC(=N2)N InChI=1S/C7H7N3/c8-7-9-5-3-1-2-4-6(5)10-7/h1-4H,(H3,8,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is a metabolite of the substance 2-aminobenzimidazole 213-280-6 934-32-7 1H-benzimidazol-2-amine Not in list C7H7N3 C1=CC=C2C(=C1)NC(=N2)N InChI=1S/C7H7N3/c8-7-9-5-3-1-2-4-6(5)10-7/h1-4H,(H3,8,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is a metabolite of the substance 2-aminobenzimidazole 213-280-6 934-32-7 1H-benzimidazol-2-amine Not in list C7H7N3 C1=CC=C2C(=C1)NC(=N2)N InChI=1S/C7H7N3/c8-7-9-5-3-1-2-4-6(5)10-7/h1-4H,(H3,8,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is a metabolite of the substance 2-aminobenzimidazole 213-280-6 934-32-7 1H-benzimidazol-2-amine Not in list C7H7N3 C1=CC=C2C(=C1)NC(=N2)N InChI=1S/C7H7N3/c8-7-9-5-3-1-2-4-6(5)10-7/h1-4H,(H3,8,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is a metabolite of the substance 2-aminobenzimidazole 213-280-6 934-32-7 1H-benzimidazol-2-amine Not in list C7H7N3 C1=CC=C2C(=C1)NC(=N2)N InChI=1S/C7H7N3/c8-7-9-5-3-1-2-4-6(5)10-7/h1-4H,(H3,8,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is a metabolite of the substance 2-aminobenzimidazole 213-280-6 934-32-7 1H-benzimidazol-2-amine Not in list C7H7N3 C1=CC=C2C(=C1)NC(=N2)N InChI=1S/C7H7N3/c8-7-9-5-3-1-2-4-6(5)10-7/h1-4H,(H3,8,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is a metabolite of the substance 2,3-phenazine-diamine 211-512-0 655-86-7 phenazine-2,3-diamine Not in list C12H10N4 C1=CC=C2C(=C1)N=C3C=C(C(=CC3=N2)N)N InChI=1S/C12H10N4/c13-7-5-11-12(6-8(7)14)16-10-4-2-1-3-9(10)15-11/h1-6H,13-14H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Positive RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is a metabolite of the substance 2,3-phenazine-diamine 211-512-0 655-86-7 phenazine-2,3-diamine Not in list C12H10N4 C1=CC=C2C(=C1)N=C3C=C(C(=CC3=N2)N)N InChI=1S/C12H10N4/c13-7-5-11-12(6-8(7)14)16-10-4-2-1-3-9(10)15-11/h1-6H,13-14H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Positive RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is a metabolite of the substance 2,3-phenazine-diamine 211-512-0 655-86-7 phenazine-2,3-diamine Not in list C12H10N4 C1=CC=C2C(=C1)N=C3C=C(C(=CC3=N2)N)N InChI=1S/C12H10N4/c13-7-5-11-12(6-8(7)14)16-10-4-2-1-3-9(10)15-11/h1-6H,13-14H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Positive RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is a metabolite of the substance 2,3-phenazine-diamine 211-512-0 655-86-7 phenazine-2,3-diamine Not in list C12H10N4 C1=CC=C2C(=C1)N=C3C=C(C(=CC3=N2)N)N InChI=1S/C12H10N4/c13-7-5-11-12(6-8(7)14)16-10-4-2-1-3-9(10)15-11/h1-6H,13-14H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Positive RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is a metabolite of the substance 2,3-phenazine-diamine 211-512-0 655-86-7 phenazine-2,3-diamine Not in list C12H10N4 C1=CC=C2C(=C1)N=C3C=C(C(=CC3=N2)N)N InChI=1S/C12H10N4/c13-7-5-11-12(6-8(7)14)16-10-4-2-1-3-9(10)15-11/h1-6H,13-14H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Positive RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is a metabolite of the substance 2,3-phenazine-diamine 211-512-0 655-86-7 phenazine-2,3-diamine Not in list C12H10N4 C1=CC=C2C(=C1)N=C3C=C(C(=CC3=N2)N)N InChI=1S/C12H10N4/c13-7-5-11-12(6-8(7)14)16-10-4-2-1-3-9(10)15-11/h1-6H,13-14H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Positive RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is a metabolite of the substance 2,3-phenazine-diamine 211-512-0 655-86-7 phenazine-2,3-diamine Not in list C12H10N4 C1=CC=C2C(=C1)N=C3C=C(C(=CC3=N2)N)N InChI=1S/C12H10N4/c13-7-5-11-12(6-8(7)14)16-10-4-2-1-3-9(10)15-11/h1-6H,13-14H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is a metabolite of the substance 2,3-phenazine-diamine 211-512-0 655-86-7 phenazine-2,3-diamine Not in list C12H10N4 C1=CC=C2C(=C1)N=C3C=C(C(=CC3=N2)N)N InChI=1S/C12H10N4/c13-7-5-11-12(6-8(7)14)16-10-4-2-1-3-9(10)15-11/h1-6H,13-14H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Positive RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is a metabolite of the substance 2,3-phenazine-diamine 211-512-0 655-86-7 phenazine-2,3-diamine Not in list C12H10N4 C1=CC=C2C(=C1)N=C3C=C(C(=CC3=N2)N)N InChI=1S/C12H10N4/c13-7-5-11-12(6-8(7)14)16-10-4-2-1-3-9(10)15-11/h1-6H,13-14H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is a metabolite of the substance 2,3-phenazine-diamine 211-512-0 655-86-7 phenazine-2,3-diamine Not in list C12H10N4 C1=CC=C2C(=C1)N=C3C=C(C(=CC3=N2)N)N InChI=1S/C12H10N4/c13-7-5-11-12(6-8(7)14)16-10-4-2-1-3-9(10)15-11/h1-6H,13-14H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Positive RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is a metabolite of the substance 2,3-phenazine-diamine 211-512-0 655-86-7 phenazine-2,3-diamine Not in list C12H10N4 C1=CC=C2C(=C1)N=C3C=C(C(=CC3=N2)N)N InChI=1S/C12H10N4/c13-7-5-11-12(6-8(7)14)16-10-4-2-1-3-9(10)15-11/h1-6H,13-14H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is a metabolite of the substance 2,3-phenazine-diamine 211-512-0 655-86-7 phenazine-2,3-diamine Not in list C12H10N4 C1=CC=C2C(=C1)N=C3C=C(C(=CC3=N2)N)N InChI=1S/C12H10N4/c13-7-5-11-12(6-8(7)14)16-10-4-2-1-3-9(10)15-11/h1-6H,13-14H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Positive RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is a metabolite of the substance 2,3-phenazine-diamine 211-512-0 655-86-7 phenazine-2,3-diamine Not in list C12H10N4 C1=CC=C2C(=C1)N=C3C=C(C(=CC3=N2)N)N InChI=1S/C12H10N4/c13-7-5-11-12(6-8(7)14)16-10-4-2-1-3-9(10)15-11/h1-6H,13-14H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Positive RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is a metabolite of the substance 2,3-phenazine-diamine 211-512-0 655-86-7 phenazine-2,3-diamine Not in list C12H10N4 C1=CC=C2C(=C1)N=C3C=C(C(=CC3=N2)N)N InChI=1S/C12H10N4/c13-7-5-11-12(6-8(7)14)16-10-4-2-1-3-9(10)15-11/h1-6H,13-14H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Positive RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is a metabolite of the substance 2,3-phenazine-diamine 211-512-0 655-86-7 phenazine-2,3-diamine Not in list C12H10N4 C1=CC=C2C(=C1)N=C3C=C(C(=CC3=N2)N)N InChI=1S/C12H10N4/c13-7-5-11-12(6-8(7)14)16-10-4-2-1-3-9(10)15-11/h1-6H,13-14H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Positive RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is a metabolite of the substance 2,3-phenazine-diamine 211-512-0 655-86-7 phenazine-2,3-diamine Not in list C12H10N4 C1=CC=C2C(=C1)N=C3C=C(C(=CC3=N2)N)N InChI=1S/C12H10N4/c13-7-5-11-12(6-8(7)14)16-10-4-2-1-3-9(10)15-11/h1-6H,13-14H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is a metabolite of the substance 2,3-phenazine-diamine 211-512-0 655-86-7 phenazine-2,3-diamine Not in list C12H10N4 C1=CC=C2C(=C1)N=C3C=C(C(=CC3=N2)N)N InChI=1S/C12H10N4/c13-7-5-11-12(6-8(7)14)16-10-4-2-1-3-9(10)15-11/h1-6H,13-14H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Positive RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is a metabolite of the substance 2,3-phenazine-diamine 211-512-0 655-86-7 phenazine-2,3-diamine Not in list C12H10N4 C1=CC=C2C(=C1)N=C3C=C(C(=CC3=N2)N)N InChI=1S/C12H10N4/c13-7-5-11-12(6-8(7)14)16-10-4-2-1-3-9(10)15-11/h1-6H,13-14H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Positive RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is a metabolite of the substance 2,3-phenazine-diamine 211-512-0 655-86-7 phenazine-2,3-diamine Not in list C12H10N4 C1=CC=C2C(=C1)N=C3C=C(C(=CC3=N2)N)N InChI=1S/C12H10N4/c13-7-5-11-12(6-8(7)14)16-10-4-2-1-3-9(10)15-11/h1-6H,13-14H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is a metabolite of the substance 2,3-phenazine-diamine 211-512-0 655-86-7 phenazine-2,3-diamine Not in list C12H10N4 C1=CC=C2C(=C1)N=C3C=C(C(=CC3=N2)N)N InChI=1S/C12H10N4/c13-7-5-11-12(6-8(7)14)16-10-4-2-1-3-9(10)15-11/h1-6H,13-14H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Positive RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is a metabolite of the substance 2,3-phenazine-diamine 211-512-0 655-86-7 phenazine-2,3-diamine Not in list C12H10N4 C1=CC=C2C(=C1)N=C3C=C(C(=CC3=N2)N)N InChI=1S/C12H10N4/c13-7-5-11-12(6-8(7)14)16-10-4-2-1-3-9(10)15-11/h1-6H,13-14H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Positive RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+1,4-Dimethylnaphthalene 209-335-9 571-58-4 single chemical entity Component is identical to the substance 1,4-Dimethylnaphthalene 209-335-9 571-58-4 1,4-dimethylnaphthalene Not in list C12H12 Cc1ccc(C)c2ccccc12 InChI=1/C12H12/c1-9-7-8-10(2)12-6-4-3-5-11(9)12/h3-8H,1-2H3 organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes without Negative RMS: The Netherlands 1,4-Dimethylnaphthalene (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 1,4-dimethylnaphthalene. 18Oct2013 2013 doi:10.2903/j.efsa.2013.3229
+Folpet 205-087-0 133-07-3 single chemical entity Component is identical to the substance Folpet 205-088-6 133-07-3 2-(Trichloromethylsulfanyl)isoindole-1,3-dione Folpet C9H4Cl3NO2S C1=CC=C2C(=C1)C(=O)N(C2=O)SC(Cl)(Cl)Cl InChI=1S/C9H4Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-4H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Positive RMS: Italy Folpet 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance folpet 31Aug2009 2009 doi:10.2903/j.efsa.2009.297r
+Folpet 205-087-0 133-07-3 single chemical entity Component is identical to the substance Folpet 205-088-6 133-07-3 2-(Trichloromethylsulfanyl)isoindole-1,3-dione Folpet C9H4Cl3NO2S C1=CC=C2C(=C1)C(=O)N(C2=O)SC(Cl)(Cl)Cl InChI=1S/C9H4Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-4H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Positive RMS: Italy Folpet 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance folpet 31Aug2009 2009 doi:10.2903/j.efsa.2009.297r
+Folpet 205-087-0 133-07-3 single chemical entity Component is identical to the substance Folpet 205-088-6 133-07-3 2-(Trichloromethylsulfanyl)isoindole-1,3-dione Folpet C9H4Cl3NO2S C1=CC=C2C(=C1)C(=O)N(C2=O)SC(Cl)(Cl)Cl InChI=1S/C9H4Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-4H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Positive RMS: Italy Folpet 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance folpet 31Aug2009 2009 doi:10.2903/j.efsa.2009.297r
+Folpet 205-087-0 133-07-3 single chemical entity Component is identical to the substance Folpet 205-088-6 133-07-3 2-(Trichloromethylsulfanyl)isoindole-1,3-dione Folpet C9H4Cl3NO2S C1=CC=C2C(=C1)C(=O)N(C2=O)SC(Cl)(Cl)Cl InChI=1S/C9H4Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-4H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Positive RMS: Italy Folpet 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance folpet 31Aug2009 2009 doi:10.2903/j.efsa.2009.297r
+Folpet 205-087-0 133-07-3 single chemical entity Component is identical to the substance Folpet 205-088-6 133-07-3 2-(Trichloromethylsulfanyl)isoindole-1,3-dione Folpet C9H4Cl3NO2S C1=CC=C2C(=C1)C(=O)N(C2=O)SC(Cl)(Cl)Cl InChI=1S/C9H4Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-4H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Positive RMS: Italy Folpet 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance folpet 31Aug2009 2009 doi:10.2903/j.efsa.2009.297r
+Folpet 205-087-0 133-07-3 single chemical entity Component is identical to the substance Folpet 205-088-6 133-07-3 2-(Trichloromethylsulfanyl)isoindole-1,3-dione Folpet C9H4Cl3NO2S C1=CC=C2C(=C1)C(=O)N(C2=O)SC(Cl)(Cl)Cl InChI=1S/C9H4Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-4H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Positive RMS: Italy Folpet 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance folpet 31Aug2009 2009 doi:10.2903/j.efsa.2009.297r
+Folpet 205-087-0 133-07-3 single chemical entity Component is identical to the substance Folpet 205-088-6 133-07-3 2-(Trichloromethylsulfanyl)isoindole-1,3-dione Folpet C9H4Cl3NO2S C1=CC=C2C(=C1)C(=O)N(C2=O)SC(Cl)(Cl)Cl InChI=1S/C9H4Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-4H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Positive RMS: Italy Folpet 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance folpet 31Aug2009 2009 doi:10.2903/j.efsa.2009.297r
+Folpet 205-087-0 133-07-3 single chemical entity Component is identical to the substance Folpet 205-088-6 133-07-3 2-(Trichloromethylsulfanyl)isoindole-1,3-dione Folpet C9H4Cl3NO2S C1=CC=C2C(=C1)C(=O)N(C2=O)SC(Cl)(Cl)Cl InChI=1S/C9H4Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-4H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Positive RMS: Italy Folpet 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance folpet 31Aug2009 2009 doi:10.2903/j.efsa.2009.297r
+Folpet 205-087-0 133-07-3 single chemical entity Component is identical to the substance Folpet 205-088-6 133-07-3 2-(Trichloromethylsulfanyl)isoindole-1,3-dione Folpet C9H4Cl3NO2S C1=CC=C2C(=C1)C(=O)N(C2=O)SC(Cl)(Cl)Cl InChI=1S/C9H4Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-4H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Positive RMS: Italy Folpet 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance folpet 31Aug2009 2009 doi:10.2903/j.efsa.2009.297r
+Folpet 205-087-0 133-07-3 single chemical entity Component is identical to the substance Folpet 205-088-6 133-07-3 2-(Trichloromethylsulfanyl)isoindole-1,3-dione Folpet C9H4Cl3NO2S C1=CC=C2C(=C1)C(=O)N(C2=O)SC(Cl)(Cl)Cl InChI=1S/C9H4Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-4H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Positive RMS: Italy Folpet 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance folpet 31Aug2009 2009 doi:10.2903/j.efsa.2009.297r
+Folpet 205-087-0 133-07-3 single chemical entity Component is identical to the substance Folpet 205-088-6 133-07-3 2-(Trichloromethylsulfanyl)isoindole-1,3-dione Folpet C9H4Cl3NO2S C1=CC=C2C(=C1)C(=O)N(C2=O)SC(Cl)(Cl)Cl InChI=1S/C9H4Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-4H organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Inconclusive RMS: Italy Folpet 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance folpet 31Aug2009 2009 doi:10.2903/j.efsa.2009.297r
+Folpet 205-087-0 133-07-3 single chemical entity Component is identical to the substance Folpet 205-088-6 133-07-3 2-(Trichloromethylsulfanyl)isoindole-1,3-dione Folpet C9H4Cl3NO2S C1=CC=C2C(=C1)C(=O)N(C2=O)SC(Cl)(Cl)Cl InChI=1S/C9H4Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-4H organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Inconclusive RMS: Italy Folpet 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance folpet 31Aug2009 2009 doi:10.2903/j.efsa.2009.297r
+Folpet 205-087-0 133-07-3 single chemical entity Component is identical to the substance Folpet 205-088-6 133-07-3 2-(Trichloromethylsulfanyl)isoindole-1,3-dione Folpet C9H4Cl3NO2S C1=CC=C2C(=C1)C(=O)N(C2=O)SC(Cl)(Cl)Cl InChI=1S/C9H4Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-4H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Inconclusive RMS: Italy Folpet 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance folpet 31Aug2009 2009 doi:10.2903/j.efsa.2009.297r
+Folpet 205-087-0 133-07-3 single chemical entity Component is identical to the substance Folpet 205-088-6 133-07-3 2-(Trichloromethylsulfanyl)isoindole-1,3-dione Folpet C9H4Cl3NO2S C1=CC=C2C(=C1)C(=O)N(C2=O)SC(Cl)(Cl)Cl InChI=1S/C9H4Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-4H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Inconclusive RMS: Italy Folpet 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance folpet 31Aug2009 2009 doi:10.2903/j.efsa.2009.297r
+Folpet 205-087-0 133-07-3 single chemical entity Component is identical to the substance Folpet 205-088-6 133-07-3 2-(Trichloromethylsulfanyl)isoindole-1,3-dione Folpet C9H4Cl3NO2S C1=CC=C2C(=C1)C(=O)N(C2=O)SC(Cl)(Cl)Cl InChI=1S/C9H4Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-4H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Positive RMS: Italy Folpet 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance folpet 31Aug2009 2009 doi:10.2903/j.efsa.2009.297r
+Folpet 205-087-0 133-07-3 single chemical entity Component is identical to the substance Folpet 205-088-6 133-07-3 2-(Trichloromethylsulfanyl)isoindole-1,3-dione Folpet C9H4Cl3NO2S C1=CC=C2C(=C1)C(=O)N(C2=O)SC(Cl)(Cl)Cl InChI=1S/C9H4Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-4H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Positive RMS: Italy Folpet 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance folpet 31Aug2009 2009 doi:10.2903/j.efsa.2009.297r
+Folpet 205-087-0 133-07-3 single chemical entity Component is identical to the substance Folpet 205-088-6 133-07-3 2-(Trichloromethylsulfanyl)isoindole-1,3-dione Folpet C9H4Cl3NO2S C1=CC=C2C(=C1)C(=O)N(C2=O)SC(Cl)(Cl)Cl InChI=1S/C9H4Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-4H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Italy Folpet 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance folpet 31Aug2009 2009 doi:10.2903/j.efsa.2009.297r
+Folpet 205-087-0 133-07-3 single chemical entity Component is identical to the substance Folpet 205-088-6 133-07-3 2-(Trichloromethylsulfanyl)isoindole-1,3-dione Folpet C9H4Cl3NO2S C1=CC=C2C(=C1)C(=O)N(C2=O)SC(Cl)(Cl)Cl InChI=1S/C9H4Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-4H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 72.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Italy Folpet 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance folpet 31Aug2009 2009 doi:10.2903/j.efsa.2009.297r
+Folpet 205-087-0 133-07-3 single chemical entity Component is identical to the substance Folpet 205-088-6 133-07-3 2-(Trichloromethylsulfanyl)isoindole-1,3-dione Folpet C9H4Cl3NO2S C1=CC=C2C(=C1)C(=O)N(C2=O)SC(Cl)(Cl)Cl InChI=1S/C9H4Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-4H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Italy Folpet 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance folpet 31Aug2009 2009 doi:10.2903/j.efsa.2009.297r
+Folpet 205-087-0 133-07-3 single chemical entity Component is identical to the substance Folpet 205-088-6 133-07-3 2-(Trichloromethylsulfanyl)isoindole-1,3-dione Folpet C9H4Cl3NO2S C1=CC=C2C(=C1)C(=O)N(C2=O)SC(Cl)(Cl)Cl InChI=1S/C9H4Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-4H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Sprague-Dawley 8 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Italy Folpet 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance folpet 31Aug2009 2009 doi:10.2903/j.efsa.2009.297r
+Folpet 205-087-0 133-07-3 single chemical entity Component is identical to the substance Folpet 205-088-6 133-07-3 2-(Trichloromethylsulfanyl)isoindole-1,3-dione Folpet C9H4Cl3NO2S C1=CC=C2C(=C1)C(=O)N(C2=O)SC(Cl)(Cl)Cl InChI=1S/C9H4Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-4H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Sprague-Dawley 8 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Italy Folpet 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance folpet 31Aug2009 2009 doi:10.2903/j.efsa.2009.297r
+Folpet 205-087-0 133-07-3 single chemical entity Component is identical to the substance Folpet 205-088-6 133-07-3 2-(Trichloromethylsulfanyl)isoindole-1,3-dione Folpet C9H4Cl3NO2S C1=CC=C2C(=C1)C(=O)N(C2=O)SC(Cl)(Cl)Cl InChI=1S/C9H4Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-4H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Sprague-Dawley 8 Male/Female oral: gavage 6.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Italy Folpet 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance folpet 31Aug2009 2009 doi:10.2903/j.efsa.2009.297r
+Folpet 205-087-0 133-07-3 single chemical entity Component is identical to the substance Folpet 205-088-6 133-07-3 2-(Trichloromethylsulfanyl)isoindole-1,3-dione Folpet C9H4Cl3NO2S C1=CC=C2C(=C1)C(=O)N(C2=O)SC(Cl)(Cl)Cl InChI=1S/C9H4Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-4H organic compound PubChem canonical SMILES PubChem InChI gene mutation mouse spot test in vivo Equivalent or similar to OECD Guideline 484 (Genetic Toxicology: Mouse Spot Test) Yes Acceptable House mouse (as animal) C57BL Female oral: feed yes, concurrent vehicle not applicable Negative RMS: Italy Folpet 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance folpet 31Aug2009 2009 doi:10.2903/j.efsa.2009.297r
+Folpet 205-087-0 133-07-3 single chemical entity Component is identical to the substance Folpet 205-088-6 133-07-3 2-(Trichloromethylsulfanyl)isoindole-1,3-dione Folpet C9H4Cl3NO2S C1=CC=C2C(=C1)C(=O)N(C2=O)SC(Cl)(Cl)Cl InChI=1S/C9H4Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-4H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration dominant lethal assay in vivo According to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) No Acceptable Rat (as animal) Male oral: gavage yes, concurrent vehicle not applicable Negative RMS: Italy Folpet 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance folpet 31Aug2009 2009 doi:10.2903/j.efsa.2009.297r
+Folpet 205-087-0 133-07-3 single chemical entity Component is identical to the substance Folpet 205-088-6 133-07-3 2-(Trichloromethylsulfanyl)isoindole-1,3-dione Folpet C9H4Cl3NO2S C1=CC=C2C(=C1)C(=O)N(C2=O)SC(Cl)(Cl)Cl InChI=1S/C9H4Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-4H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration dominant lethal assay in vivo No guideline followed Not reported Not applicable Acceptable Rat (as animal) Not reported Male intraperitoneal yes, concurrent vehicle not applicable Negative RMS: Italy Folpet (Final addendum) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance folpet 31Aug2009 2009 doi:10.2903/j.efsa.2009.297r
+Folpet 205-087-0 133-07-3 single chemical entity Component is identical to the substance Folpet 205-088-6 133-07-3 2-(Trichloromethylsulfanyl)isoindole-1,3-dione Folpet C9H4Cl3NO2S C1=CC=C2C(=C1)C(=O)N(C2=O)SC(Cl)(Cl)Cl InChI=1S/C9H4Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-4H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration dominant lethal assay in vivo No guideline followed Not reported Not applicable Acceptable Rat (as animal) Not reported Male oral: gavage yes, concurrent vehicle not applicable Negative RMS: Italy Folpet (Final addendum) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance folpet 31Aug2009 2009 doi:10.2903/j.efsa.2009.297r
+Folpet 205-087-0 133-07-3 single chemical entity Component is identical to the substance Folpet 205-088-6 133-07-3 2-(Trichloromethylsulfanyl)isoindole-1,3-dione Folpet C9H4Cl3NO2S C1=CC=C2C(=C1)C(=O)N(C2=O)SC(Cl)(Cl)Cl InChI=1S/C9H4Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-4H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo No guideline followed Not reported Not applicable Acceptable House mouse (as animal) CD-1 3 Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Italy Folpet (Final addendum) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance folpet 31Aug2009 2009 doi:10.2903/j.efsa.2009.297r
+Folpet 205-087-0 133-07-3 single chemical entity Component is identical to the substance Folpet 205-088-6 133-07-3 2-(Trichloromethylsulfanyl)isoindole-1,3-dione Folpet C9H4Cl3NO2S C1=CC=C2C(=C1)C(=O)N(C2=O)SC(Cl)(Cl)Cl InChI=1S/C9H4Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-4H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo No guideline followed Not reported Not applicable Acceptable House mouse (as animal) CD-1 8 Female oral: gavage 6.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Italy Folpet (Final addendum) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance folpet 31Aug2009 2009 doi:10.2903/j.efsa.2009.297r
+Folpet 205-087-0 133-07-3 single chemical entity Component is identical to the substance Folpet 205-088-6 133-07-3 2-(Trichloromethylsulfanyl)isoindole-1,3-dione Folpet C9H4Cl3NO2S C1=CC=C2C(=C1)C(=O)N(C2=O)SC(Cl)(Cl)Cl InChI=1S/C9H4Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-4H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo No guideline followed Not reported Not applicable Acceptable House mouse (as animal) CD-1 8 Female oral: gavage 2.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Italy Folpet (Final addendum) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance folpet 31Aug2009 2009 doi:10.2903/j.efsa.2009.297r
+Florasulam 604-488-1 145701-23-1 single chemical entity Component is identical to the substance Florasulam 604-488-1 145701-23-1 N-(2,6-difluorophenyl)-8-fluoro-5-methoxy-[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide Florasulam C12H8F3N5O3S COC1=NC=C(C2=NC(=NN21)S(=O)(=O)NC3=C(C=CC=C3F)F)F InChI=1S/C12H8F3N5O3S/c1-23-12-16-5-8(15)10-17-11(18-20(10)12)24(21,22)19-9-6(13)3-2-4-7(9)14/h2-5,19H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium Florasulam 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam 13Jan2015 2015 doi:10.2903/j.efsa.2015.3984
+Florasulam 604-488-1 145701-23-1 single chemical entity Component is identical to the substance Florasulam 604-488-1 145701-23-1 N-(2,6-difluorophenyl)-8-fluoro-5-methoxy-[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide Florasulam C12H8F3N5O3S COC1=NC=C(C2=NC(=NN21)S(=O)(=O)NC3=C(C=CC=C3F)F)F InChI=1S/C12H8F3N5O3S/c1-23-12-16-5-8(15)10-17-11(18-20(10)12)24(21,22)19-9-6(13)3-2-4-7(9)14/h2-5,19H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium Florasulam 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam 13Jan2015 2015 doi:10.2903/j.efsa.2015.3984
+Florasulam 604-488-1 145701-23-1 single chemical entity Component is identical to the substance Florasulam 604-488-1 145701-23-1 N-(2,6-difluorophenyl)-8-fluoro-5-methoxy-[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide Florasulam C12H8F3N5O3S COC1=NC=C(C2=NC(=NN21)S(=O)(=O)NC3=C(C=CC=C3F)F)F InChI=1S/C12H8F3N5O3S/c1-23-12-16-5-8(15)10-17-11(18-20(10)12)24(21,22)19-9-6(13)3-2-4-7(9)14/h2-5,19H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Poland Florasulam (RAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam 13Jan2015 2015 doi:10.2903/j.efsa.2015.3984
+Florasulam 604-488-1 145701-23-1 single chemical entity Component is identical to the substance Florasulam 604-488-1 145701-23-1 N-(2,6-difluorophenyl)-8-fluoro-5-methoxy-[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide Florasulam C12H8F3N5O3S COC1=NC=C(C2=NC(=NN21)S(=O)(=O)NC3=C(C=CC=C3F)F)F InChI=1S/C12H8F3N5O3S/c1-23-12-16-5-8(15)10-17-11(18-20(10)12)24(21,22)19-9-6(13)3-2-4-7(9)14/h2-5,19H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium Florasulam 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam 13Jan2015 2015 doi:10.2903/j.efsa.2015.3984
+Florasulam 604-488-1 145701-23-1 single chemical entity Component is identical to the substance Florasulam 604-488-1 145701-23-1 N-(2,6-difluorophenyl)-8-fluoro-5-methoxy-[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide Florasulam C12H8F3N5O3S COC1=NC=C(C2=NC(=NN21)S(=O)(=O)NC3=C(C=CC=C3F)F)F InChI=1S/C12H8F3N5O3S/c1-23-12-16-5-8(15)10-17-11(18-20(10)12)24(21,22)19-9-6(13)3-2-4-7(9)14/h2-5,19H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium Florasulam 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam 13Jan2015 2015 doi:10.2903/j.efsa.2015.3984
+Florasulam 604-488-1 145701-23-1 single chemical entity Component is identical to the substance Florasulam 604-488-1 145701-23-1 N-(2,6-difluorophenyl)-8-fluoro-5-methoxy-[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide Florasulam C12H8F3N5O3S COC1=NC=C(C2=NC(=NN21)S(=O)(=O)NC3=C(C=CC=C3F)F)F InChI=1S/C12H8F3N5O3S/c1-23-12-16-5-8(15)10-17-11(18-20(10)12)24(21,22)19-9-6(13)3-2-4-7(9)14/h2-5,19H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Belgium Florasulam 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam 13Jan2015 2015 doi:10.2903/j.efsa.2015.3984
+Florasulam 604-488-1 145701-23-1 single chemical entity Component is identical to the substance Florasulam 604-488-1 145701-23-1 N-(2,6-difluorophenyl)-8-fluoro-5-methoxy-[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide Florasulam C12H8F3N5O3S COC1=NC=C(C2=NC(=NN21)S(=O)(=O)NC3=C(C=CC=C3F)F)F InChI=1S/C12H8F3N5O3S/c1-23-12-16-5-8(15)10-17-11(18-20(10)12)24(21,22)19-9-6(13)3-2-4-7(9)14/h2-5,19H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium Florasulam 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam 13Jan2015 2015 doi:10.2903/j.efsa.2015.3984
+Florasulam 604-488-1 145701-23-1 single chemical entity Component is identical to the substance Florasulam 604-488-1 145701-23-1 N-(2,6-difluorophenyl)-8-fluoro-5-methoxy-[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide Florasulam C12H8F3N5O3S COC1=NC=C(C2=NC(=NN21)S(=O)(=O)NC3=C(C=CC=C3F)F)F InChI=1S/C12H8F3N5O3S/c1-23-12-16-5-8(15)10-17-11(18-20(10)12)24(21,22)19-9-6(13)3-2-4-7(9)14/h2-5,19H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium Florasulam 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam 13Jan2015 2015 doi:10.2903/j.efsa.2015.3984
+Florasulam 604-488-1 145701-23-1 single chemical entity Component is identical to the substance Florasulam 604-488-1 145701-23-1 N-(2,6-difluorophenyl)-8-fluoro-5-methoxy-[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide Florasulam C12H8F3N5O3S COC1=NC=C(C2=NC(=NN21)S(=O)(=O)NC3=C(C=CC=C3F)F)F InChI=1S/C12H8F3N5O3S/c1-23-12-16-5-8(15)10-17-11(18-20(10)12)24(21,22)19-9-6(13)3-2-4-7(9)14/h2-5,19H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium Florasulam 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam 13Jan2015 2015 doi:10.2903/j.efsa.2015.3984
+Florasulam 604-488-1 145701-23-1 single chemical entity Component is identical to the substance Florasulam 604-488-1 145701-23-1 N-(2,6-difluorophenyl)-8-fluoro-5-methoxy-[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide Florasulam C12H8F3N5O3S COC1=NC=C(C2=NC(=NN21)S(=O)(=O)NC3=C(C=CC=C3F)F)F InChI=1S/C12H8F3N5O3S/c1-23-12-16-5-8(15)10-17-11(18-20(10)12)24(21,22)19-9-6(13)3-2-4-7(9)14/h2-5,19H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Belgium Florasulam 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam 13Jan2015 2015 doi:10.2903/j.efsa.2015.3984
+Florasulam 604-488-1 145701-23-1 single chemical entity Component is identical to the substance Florasulam 604-488-1 145701-23-1 N-(2,6-difluorophenyl)-8-fluoro-5-methoxy-[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide Florasulam C12H8F3N5O3S COC1=NC=C(C2=NC(=NN21)S(=O)(=O)NC3=C(C=CC=C3F)F)F InChI=1S/C12H8F3N5O3S/c1-23-12-16-5-8(15)10-17-11(18-20(10)12)24(21,22)19-9-6(13)3-2-4-7(9)14/h2-5,19H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Belgium Florasulam 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam 13Jan2015 2015 doi:10.2903/j.efsa.2015.3984
+Florasulam 604-488-1 145701-23-1 single chemical entity Component is identical to the substance Florasulam 604-488-1 145701-23-1 N-(2,6-difluorophenyl)-8-fluoro-5-methoxy-[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide Florasulam C12H8F3N5O3S COC1=NC=C(C2=NC(=NN21)S(=O)(=O)NC3=C(C=CC=C3F)F)F InChI=1S/C12H8F3N5O3S/c1-23-12-16-5-8(15)10-17-11(18-20(10)12)24(21,22)19-9-6(13)3-2-4-7(9)14/h2-5,19H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Belgium Florasulam 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam 13Jan2015 2015 doi:10.2903/j.efsa.2015.3984
+Florasulam 604-488-1 145701-23-1 single chemical entity Component is identical to the substance Florasulam 604-488-1 145701-23-1 N-(2,6-difluorophenyl)-8-fluoro-5-methoxy-[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide Florasulam C12H8F3N5O3S COC1=NC=C(C2=NC(=NN21)S(=O)(=O)NC3=C(C=CC=C3F)F)F InChI=1S/C12H8F3N5O3S/c1-23-12-16-5-8(15)10-17-11(18-20(10)12)24(21,22)19-9-6(13)3-2-4-7(9)14/h2-5,19H,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Rat (as animal) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Belgium Florasulam 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam 13Jan2015 2015 doi:10.2903/j.efsa.2015.3984
+Florasulam 604-488-1 145701-23-1 single chemical entity Component is identical to the substance Florasulam 604-488-1 145701-23-1 N-(2,6-difluorophenyl)-8-fluoro-5-methoxy-[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide Florasulam C12H8F3N5O3S COC1=NC=C(C2=NC(=NN21)S(=O)(=O)NC3=C(C=CC=C3F)F)F InChI=1S/C12H8F3N5O3S/c1-23-12-16-5-8(15)10-17-11(18-20(10)12)24(21,22)19-9-6(13)3-2-4-7(9)14/h2-5,19H,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Rat (as animal) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Belgium Florasulam 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam 13Jan2015 2015 doi:10.2903/j.efsa.2015.3984
+Florasulam 604-488-1 145701-23-1 single chemical entity Component is identical to the substance Florasulam 604-488-1 145701-23-1 N-(2,6-difluorophenyl)-8-fluoro-5-methoxy-[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide Florasulam C12H8F3N5O3S COC1=NC=C(C2=NC(=NN21)S(=O)(=O)NC3=C(C=CC=C3F)F)F InChI=1S/C12H8F3N5O3S/c1-23-12-16-5-8(15)10-17-11(18-20(10)12)24(21,22)19-9-6(13)3-2-4-7(9)14/h2-5,19H,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Belgium Florasulam 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam 13Jan2015 2015 doi:10.2903/j.efsa.2015.3984
+Florasulam 604-488-1 145701-23-1 single chemical entity Component is identical to the substance Florasulam 604-488-1 145701-23-1 N-(2,6-difluorophenyl)-8-fluoro-5-methoxy-[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide Florasulam C12H8F3N5O3S COC1=NC=C(C2=NC(=NN21)S(=O)(=O)NC3=C(C=CC=C3F)F)F InChI=1S/C12H8F3N5O3S/c1-23-12-16-5-8(15)10-17-11(18-20(10)12)24(21,22)19-9-6(13)3-2-4-7(9)14/h2-5,19H,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 72.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Belgium Florasulam 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam 13Jan2015 2015 doi:10.2903/j.efsa.2015.3984
+Florasulam 604-488-1 145701-23-1 single chemical entity Component is identical to the substance Florasulam 604-488-1 145701-23-1 N-(2,6-difluorophenyl)-8-fluoro-5-methoxy-[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide Florasulam C12H8F3N5O3S COC1=NC=C(C2=NC(=NN21)S(=O)(=O)NC3=C(C=CC=C3F)F)F InChI=1S/C12H8F3N5O3S/c1-23-12-16-5-8(15)10-17-11(18-20(10)12)24(21,22)19-9-6(13)3-2-4-7(9)14/h2-5,19H,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Belgium Florasulam 1999 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam 13Jan2015 2015 doi:10.2903/j.efsa.2015.3984
+Florasulam 604-488-1 145701-23-1 single chemical entity Component is a metabolite of the substance N-(2,6-difluorophenyl)-8-fluoro-5-oxo-5,6-dihydro[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide N-(2,6-difluorophenyl)-8-fluoro-5-hydroxy[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide Not in list C11H6F3N5O3S Fc3cccc(F)c3NS(=O)(=O)c1nc2c(F)cnc(O)n2n1 InChI=1/C11H6F3N5O3S/c12-5-2-1-3-6(13)8(5)18-23(21,22)10-16-9-7(14)4-15-11(20)19(9)17-10/h1-4,18H,(H,15,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Poland Florasulam (RAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam 13Jan2015 2015 doi:10.2903/j.efsa.2015.3984
+Florasulam 604-488-1 145701-23-1 single chemical entity Component is a metabolite of the substance N-(2,6-difluorophenyl)-8-fluoro-5-oxo-5,6-dihydro[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide N-(2,6-difluorophenyl)-8-fluoro-5-hydroxy[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide Not in list C11H6F3N5O3S Fc3cccc(F)c3NS(=O)(=O)c1nc2c(F)cnc(O)n2n1 InChI=1/C11H6F3N5O3S/c12-5-2-1-3-6(13)8(5)18-23(21,22)10-16-9-7(14)4-15-11(20)19(9)17-10/h1-4,18H,(H,15,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Poland Florasulam (RAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam 13Jan2015 2015 doi:10.2903/j.efsa.2015.3984
+Florasulam 604-488-1 145701-23-1 single chemical entity Component is a metabolite of the substance N-(2,6-difluorophenyl)-8-fluoro-5-oxo-5,6-dihydro[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide N-(2,6-difluorophenyl)-8-fluoro-5-hydroxy[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide Not in list C11H6F3N5O3S Fc3cccc(F)c3NS(=O)(=O)c1nc2c(F)cnc(O)n2n1 InChI=1/C11H6F3N5O3S/c12-5-2-1-3-6(13)8(5)18-23(21,22)10-16-9-7(14)4-15-11(20)19(9)17-10/h1-4,18H,(H,15,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Poland Florasulam (RAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam 13Jan2015 2015 doi:10.2903/j.efsa.2015.3984
+Florasulam 604-488-1 145701-23-1 single chemical entity Component is a metabolite of the substance N-(2,6-difluorophenyl)-8-fluoro-5-oxo-5,6-dihydro[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide N-(2,6-difluorophenyl)-8-fluoro-5-hydroxy[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide Not in list C11H6F3N5O3S Fc3cccc(F)c3NS(=O)(=O)c1nc2c(F)cnc(O)n2n1 InChI=1/C11H6F3N5O3S/c12-5-2-1-3-6(13)8(5)18-23(21,22)10-16-9-7(14)4-15-11(20)19(9)17-10/h1-4,18H,(H,15,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Poland Florasulam (RAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam 13Jan2015 2015 doi:10.2903/j.efsa.2015.3984
+Florasulam 604-488-1 145701-23-1 single chemical entity Component is a metabolite of the substance N-(2,6-difluorophenyl)-8-fluoro-5-oxo-5,6-dihydro[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide N-(2,6-difluorophenyl)-8-fluoro-5-hydroxy[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide Not in list C11H6F3N5O3S Fc3cccc(F)c3NS(=O)(=O)c1nc2c(F)cnc(O)n2n1 InChI=1/C11H6F3N5O3S/c12-5-2-1-3-6(13)8(5)18-23(21,22)10-16-9-7(14)4-15-11(20)19(9)17-10/h1-4,18H,(H,15,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Poland Florasulam (RAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam 13Jan2015 2015 doi:10.2903/j.efsa.2015.3984
+Florasulam 604-488-1 145701-23-1 single chemical entity Component is a metabolite of the substance N-(2,6-difluorophenyl)-8-fluoro-5-oxo-5,6-dihydro[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide N-(2,6-difluorophenyl)-8-fluoro-5-hydroxy[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide Not in list C11H6F3N5O3S Fc3cccc(F)c3NS(=O)(=O)c1nc2c(F)cnc(O)n2n1 InChI=1/C11H6F3N5O3S/c12-5-2-1-3-6(13)8(5)18-23(21,22)10-16-9-7(14)4-15-11(20)19(9)17-10/h1-4,18H,(H,15,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Poland Florasulam (RAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam 13Jan2015 2015 doi:10.2903/j.efsa.2015.3984
+Florasulam 604-488-1 145701-23-1 single chemical entity Component is a metabolite of the substance N-(2,6-difluorophenyl)-8-fluoro-5-oxo-5,6-dihydro[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide N-(2,6-difluorophenyl)-8-fluoro-5-hydroxy[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide Not in list C11H6F3N5O3S Fc3cccc(F)c3NS(=O)(=O)c1nc2c(F)cnc(O)n2n1 InChI=1/C11H6F3N5O3S/c12-5-2-1-3-6(13)8(5)18-23(21,22)10-16-9-7(14)4-15-11(20)19(9)17-10/h1-4,18H,(H,15,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Poland Florasulam (RAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam 13Jan2015 2015 doi:10.2903/j.efsa.2015.3984
+Florasulam 604-488-1 145701-23-1 single chemical entity Component is a metabolite of the substance N-(2,6-difluorophenyl)-8-fluoro-5-oxo-5,6-dihydro[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide N-(2,6-difluorophenyl)-8-fluoro-5-hydroxy[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide Not in list C11H6F3N5O3S Fc3cccc(F)c3NS(=O)(=O)c1nc2c(F)cnc(O)n2n1 InChI=1/C11H6F3N5O3S/c12-5-2-1-3-6(13)8(5)18-23(21,22)10-16-9-7(14)4-15-11(20)19(9)17-10/h1-4,18H,(H,15,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Poland Florasulam (RAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam 13Jan2015 2015 doi:10.2903/j.efsa.2015.3984
+Florasulam 604-488-1 145701-23-1 single chemical entity Component is a metabolite of the substance N-(2,6-difluorophenyl)-8-fluoro-5-oxo-5,6-dihydro[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide N-(2,6-difluorophenyl)-8-fluoro-5-hydroxy[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide Not in list C11H6F3N5O3S Fc3cccc(F)c3NS(=O)(=O)c1nc2c(F)cnc(O)n2n1 InChI=1/C11H6F3N5O3S/c12-5-2-1-3-6(13)8(5)18-23(21,22)10-16-9-7(14)4-15-11(20)19(9)17-10/h1-4,18H,(H,15,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Poland Florasulam (RAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam 13Jan2015 2015 doi:10.2903/j.efsa.2015.3984
+Florasulam 604-488-1 145701-23-1 single chemical entity Component is a metabolite of the substance N-(2,6-difluorophenyl)-8-fluoro-5-oxo-5,6-dihydro[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide N-(2,6-difluorophenyl)-8-fluoro-5-hydroxy[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide Not in list C11H6F3N5O3S Fc3cccc(F)c3NS(=O)(=O)c1nc2c(F)cnc(O)n2n1 InChI=1/C11H6F3N5O3S/c12-5-2-1-3-6(13)8(5)18-23(21,22)10-16-9-7(14)4-15-11(20)19(9)17-10/h1-4,18H,(H,15,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Poland Florasulam (RAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam 13Jan2015 2015 doi:10.2903/j.efsa.2015.3984
+Florasulam 604-488-1 145701-23-1 single chemical entity Component is a metabolite of the substance N-(2,6-difluorophenyl)-8-fluoro-5-oxo-5,6-dihydro[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide N-(2,6-difluorophenyl)-8-fluoro-5-hydroxy[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide Not in list C11H6F3N5O3S Fc3cccc(F)c3NS(=O)(=O)c1nc2c(F)cnc(O)n2n1 InChI=1/C11H6F3N5O3S/c12-5-2-1-3-6(13)8(5)18-23(21,22)10-16-9-7(14)4-15-11(20)19(9)17-10/h1-4,18H,(H,15,20) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Rat (as animal) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Poland Florasulam (RAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam 13Jan2015 2015 doi:10.2903/j.efsa.2015.3984
+Florasulam 604-488-1 145701-23-1 single chemical entity Component is a metabolite of the substance N-(2,6-difluorophenyl)-8-fluoro-5-oxo-5,6-dihydro[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide N-(2,6-difluorophenyl)-8-fluoro-5-hydroxy[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide Not in list C11H6F3N5O3S Fc3cccc(F)c3NS(=O)(=O)c1nc2c(F)cnc(O)n2n1 InChI=1/C11H6F3N5O3S/c12-5-2-1-3-6(13)8(5)18-23(21,22)10-16-9-7(14)4-15-11(20)19(9)17-10/h1-4,18H,(H,15,20) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Rat (as animal) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Poland Florasulam (RAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam 13Jan2015 2015 doi:10.2903/j.efsa.2015.3984
+Florasulam 604-488-1 145701-23-1 single chemical entity Component is a metabolite of the substance N-(2,6-difluorophenyl)-8-fluoro-5-oxo-5,6-dihydro[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide N-(2,6-difluorophenyl)-8-fluoro-5-hydroxy[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide Not in list C11H6F3N5O3S Fc3cccc(F)c3NS(=O)(=O)c1nc2c(F)cnc(O)n2n1 InChI=1/C11H6F3N5O3S/c12-5-2-1-3-6(13)8(5)18-23(21,22)10-16-9-7(14)4-15-11(20)19(9)17-10/h1-4,18H,(H,15,20) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Poland Florasulam (RAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam 13Jan2015 2015 doi:10.2903/j.efsa.2015.3984
+Florasulam 604-488-1 145701-23-1 single chemical entity Component is a metabolite of the substance N-(2,6-difluorophenyl)-8-fluoro-5-oxo-5,6-dihydro[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide N-(2,6-difluorophenyl)-8-fluoro-5-hydroxy[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide Not in list C11H6F3N5O3S Fc3cccc(F)c3NS(=O)(=O)c1nc2c(F)cnc(O)n2n1 InChI=1/C11H6F3N5O3S/c12-5-2-1-3-6(13)8(5)18-23(21,22)10-16-9-7(14)4-15-11(20)19(9)17-10/h1-4,18H,(H,15,20) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Poland Florasulam (RAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam 13Jan2015 2015 doi:10.2903/j.efsa.2015.3984
+Florasulam 604-488-1 145701-23-1 single chemical entity Component is a metabolite of the substance 3-sulfamoyl-1H-1,2,4-triazole-5-carboxylic acid 313963-93-8 5-sulfamoyl-1H-1,2,4-triazole-3-carboxylic acid Not in list C3H4N4O4S C1(=NNC(=N1)S(=O)(=O)N)C(=O)O InChI=1S/C3H4N4O4S/c4-12(10,11)3-5-1(2(8)9)6-7-3/h(H,8,9)(H2,4,10,11)(H,5,6,7) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Poland Florasulam (RAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam 13Jan2015 2015 doi:10.2903/j.efsa.2015.3984
+Florasulam 604-488-1 145701-23-1 single chemical entity Component is a metabolite of the substance 3-sulfamoyl-1H-1,2,4-triazole-5-carboxylic acid 313963-93-8 5-sulfamoyl-1H-1,2,4-triazole-3-carboxylic acid Not in list C3H4N4O4S C1(=NNC(=N1)S(=O)(=O)N)C(=O)O InChI=1S/C3H4N4O4S/c4-12(10,11)3-5-1(2(8)9)6-7-3/h(H,8,9)(H2,4,10,11)(H,5,6,7) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Poland Florasulam (RAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam 13Jan2015 2015 doi:10.2903/j.efsa.2015.3984
+Florasulam 604-488-1 145701-23-1 single chemical entity Component is a metabolite of the substance 3-sulfamoyl-1H-1,2,4-triazole-5-carboxylic acid 313963-93-8 5-sulfamoyl-1H-1,2,4-triazole-3-carboxylic acid Not in list C3H4N4O4S C1(=NNC(=N1)S(=O)(=O)N)C(=O)O InChI=1S/C3H4N4O4S/c4-12(10,11)3-5-1(2(8)9)6-7-3/h(H,8,9)(H2,4,10,11)(H,5,6,7) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Poland Florasulam (RAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam 13Jan2015 2015 doi:10.2903/j.efsa.2015.3984
+Florasulam 604-488-1 145701-23-1 single chemical entity Component is a metabolite of the substance 3-sulfamoyl-1H-1,2,4-triazole-5-carboxylic acid 313963-93-8 5-sulfamoyl-1H-1,2,4-triazole-3-carboxylic acid Not in list C3H4N4O4S C1(=NNC(=N1)S(=O)(=O)N)C(=O)O InChI=1S/C3H4N4O4S/c4-12(10,11)3-5-1(2(8)9)6-7-3/h(H,8,9)(H2,4,10,11)(H,5,6,7) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Poland Florasulam (RAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam 13Jan2015 2015 doi:10.2903/j.efsa.2015.3984
+Florasulam 604-488-1 145701-23-1 single chemical entity Component is a metabolite of the substance 3-sulfamoyl-1H-1,2,4-triazole-5-carboxylic acid 313963-93-8 5-sulfamoyl-1H-1,2,4-triazole-3-carboxylic acid Not in list C3H4N4O4S C1(=NNC(=N1)S(=O)(=O)N)C(=O)O InChI=1S/C3H4N4O4S/c4-12(10,11)3-5-1(2(8)9)6-7-3/h(H,8,9)(H2,4,10,11)(H,5,6,7) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Poland Florasulam (RAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam 13Jan2015 2015 doi:10.2903/j.efsa.2015.3984
+Florasulam 604-488-1 145701-23-1 single chemical entity Component is a metabolite of the substance 3-sulfamoyl-1H-1,2,4-triazole-5-carboxylic acid 313963-93-8 5-sulfamoyl-1H-1,2,4-triazole-3-carboxylic acid Not in list C3H4N4O4S C1(=NNC(=N1)S(=O)(=O)N)C(=O)O InChI=1S/C3H4N4O4S/c4-12(10,11)3-5-1(2(8)9)6-7-3/h(H,8,9)(H2,4,10,11)(H,5,6,7) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Poland Florasulam (RAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam 13Jan2015 2015 doi:10.2903/j.efsa.2015.3984
+Florasulam 604-488-1 145701-23-1 single chemical entity Component is a metabolite of the substance 3-sulfamoyl-1H-1,2,4-triazole-5-carboxylic acid 313963-93-8 5-sulfamoyl-1H-1,2,4-triazole-3-carboxylic acid Not in list C3H4N4O4S C1(=NNC(=N1)S(=O)(=O)N)C(=O)O InChI=1S/C3H4N4O4S/c4-12(10,11)3-5-1(2(8)9)6-7-3/h(H,8,9)(H2,4,10,11)(H,5,6,7) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Poland Florasulam (RAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam 13Jan2015 2015 doi:10.2903/j.efsa.2015.3984
+Florasulam 604-488-1 145701-23-1 single chemical entity Component is a metabolite of the substance 3-sulfamoyl-1H-1,2,4-triazole-5-carboxylic acid 313963-93-8 5-sulfamoyl-1H-1,2,4-triazole-3-carboxylic acid Not in list C3H4N4O4S C1(=NNC(=N1)S(=O)(=O)N)C(=O)O InChI=1S/C3H4N4O4S/c4-12(10,11)3-5-1(2(8)9)6-7-3/h(H,8,9)(H2,4,10,11)(H,5,6,7) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Poland Florasulam (RAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam 13Jan2015 2015 doi:10.2903/j.efsa.2015.3984
+Florasulam 604-488-1 145701-23-1 single chemical entity Component is a metabolite of the substance 3-sulfamoyl-1H-1,2,4-triazole-5-carboxylic acid 313963-93-8 5-sulfamoyl-1H-1,2,4-triazole-3-carboxylic acid Not in list C3H4N4O4S C1(=NNC(=N1)S(=O)(=O)N)C(=O)O InChI=1S/C3H4N4O4S/c4-12(10,11)3-5-1(2(8)9)6-7-3/h(H,8,9)(H2,4,10,11)(H,5,6,7) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Poland Florasulam (RAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam 13Jan2015 2015 doi:10.2903/j.efsa.2015.3984
+Florasulam 604-488-1 145701-23-1 single chemical entity Component is a metabolite of the substance 3-sulfamoyl-1H-1,2,4-triazole-5-carboxylic acid 313963-93-8 5-sulfamoyl-1H-1,2,4-triazole-3-carboxylic acid Not in list C3H4N4O4S C1(=NNC(=N1)S(=O)(=O)N)C(=O)O InChI=1S/C3H4N4O4S/c4-12(10,11)3-5-1(2(8)9)6-7-3/h(H,8,9)(H2,4,10,11)(H,5,6,7) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Poland Florasulam (RAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam 13Jan2015 2015 doi:10.2903/j.efsa.2015.3984
+Florasulam 604-488-1 145701-23-1 single chemical entity Component is a metabolite of the substance 3-sulfamoyl-1H-1,2,4-triazole-5-carboxylic acid 313963-93-8 5-sulfamoyl-1H-1,2,4-triazole-3-carboxylic acid Not in list C3H4N4O4S C1(=NNC(=N1)S(=O)(=O)N)C(=O)O InChI=1S/C3H4N4O4S/c4-12(10,11)3-5-1(2(8)9)6-7-3/h(H,8,9)(H2,4,10,11)(H,5,6,7) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Poland Florasulam (RAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam 13Jan2015 2015 doi:10.2903/j.efsa.2015.3984
+Florasulam 604-488-1 145701-23-1 single chemical entity Component is a metabolite of the substance 3-sulfamoyl-1H-1,2,4-triazole-5-carboxylic acid 313963-93-8 5-sulfamoyl-1H-1,2,4-triazole-3-carboxylic acid Not in list C3H4N4O4S C1(=NNC(=N1)S(=O)(=O)N)C(=O)O InChI=1S/C3H4N4O4S/c4-12(10,11)3-5-1(2(8)9)6-7-3/h(H,8,9)(H2,4,10,11)(H,5,6,7) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Poland Florasulam (RAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam 13Jan2015 2015 doi:10.2903/j.efsa.2015.3984
+Florasulam 604-488-1 145701-23-1 single chemical entity Component is a metabolite of the substance 3-sulfamoyl-1H-1,2,4-triazole-5-carboxylic acid 313963-93-8 5-sulfamoyl-1H-1,2,4-triazole-3-carboxylic acid Not in list C3H4N4O4S C1(=NNC(=N1)S(=O)(=O)N)C(=O)O InChI=1S/C3H4N4O4S/c4-12(10,11)3-5-1(2(8)9)6-7-3/h(H,8,9)(H2,4,10,11)(H,5,6,7) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Rat (as animal) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Poland Florasulam (RAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam 13Jan2015 2015 doi:10.2903/j.efsa.2015.3984
+Florasulam 604-488-1 145701-23-1 single chemical entity Component is a metabolite of the substance 3-sulfamoyl-1H-1,2,4-triazole-5-carboxylic acid 313963-93-8 5-sulfamoyl-1H-1,2,4-triazole-3-carboxylic acid Not in list C3H4N4O4S C1(=NNC(=N1)S(=O)(=O)N)C(=O)O InChI=1S/C3H4N4O4S/c4-12(10,11)3-5-1(2(8)9)6-7-3/h(H,8,9)(H2,4,10,11)(H,5,6,7) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Rat (as animal) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Poland Florasulam (RAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam 13Jan2015 2015 doi:10.2903/j.efsa.2015.3984
+Florasulam 604-488-1 145701-23-1 single chemical entity Component is a metabolite of the substance 1H-1,2,4-triazole-3-sulfonamide 89517-96-4 1H-1,2,4-triazole-5-sulfonamide Not in list C2H4N4O2S C1=NNC(=N1)S(=O)(=O)N InChI=1S/C2H4N4O2S/c3-9(7,8)2-4-1-5-6-2/h1H,(H2,3,7,8)(H,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Poland Florasulam (RAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam 13Jan2015 2015 doi:10.2903/j.efsa.2015.3984
+Florasulam 604-488-1 145701-23-1 single chemical entity Component is a metabolite of the substance 1H-1,2,4-triazole-3-sulfonamide 89517-96-4 1H-1,2,4-triazole-5-sulfonamide Not in list C2H4N4O2S C1=NNC(=N1)S(=O)(=O)N InChI=1S/C2H4N4O2S/c3-9(7,8)2-4-1-5-6-2/h1H,(H2,3,7,8)(H,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Poland Florasulam (RAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam 13Jan2015 2015 doi:10.2903/j.efsa.2015.3984
+Florasulam 604-488-1 145701-23-1 single chemical entity Component is a metabolite of the substance 1H-1,2,4-triazole-3-sulfonamide 89517-96-4 1H-1,2,4-triazole-5-sulfonamide Not in list C2H4N4O2S C1=NNC(=N1)S(=O)(=O)N InChI=1S/C2H4N4O2S/c3-9(7,8)2-4-1-5-6-2/h1H,(H2,3,7,8)(H,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Poland Florasulam (RAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam 13Jan2015 2015 doi:10.2903/j.efsa.2015.3984
+Florasulam 604-488-1 145701-23-1 single chemical entity Component is a metabolite of the substance 1H-1,2,4-triazole-3-sulfonamide 89517-96-4 1H-1,2,4-triazole-5-sulfonamide Not in list C2H4N4O2S C1=NNC(=N1)S(=O)(=O)N InChI=1S/C2H4N4O2S/c3-9(7,8)2-4-1-5-6-2/h1H,(H2,3,7,8)(H,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Poland Florasulam (RAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam 13Jan2015 2015 doi:10.2903/j.efsa.2015.3984
+Florasulam 604-488-1 145701-23-1 single chemical entity Component is a metabolite of the substance 1H-1,2,4-triazole-3-sulfonamide 89517-96-4 1H-1,2,4-triazole-5-sulfonamide Not in list C2H4N4O2S C1=NNC(=N1)S(=O)(=O)N InChI=1S/C2H4N4O2S/c3-9(7,8)2-4-1-5-6-2/h1H,(H2,3,7,8)(H,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Poland Florasulam (RAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam 13Jan2015 2015 doi:10.2903/j.efsa.2015.3984
+Florasulam 604-488-1 145701-23-1 single chemical entity Component is a metabolite of the substance 1H-1,2,4-triazole-3-sulfonamide 89517-96-4 1H-1,2,4-triazole-5-sulfonamide Not in list C2H4N4O2S C1=NNC(=N1)S(=O)(=O)N InChI=1S/C2H4N4O2S/c3-9(7,8)2-4-1-5-6-2/h1H,(H2,3,7,8)(H,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Poland Florasulam (RAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam 13Jan2015 2015 doi:10.2903/j.efsa.2015.3984
+Florasulam 604-488-1 145701-23-1 single chemical entity Component is a metabolite of the substance 1H-1,2,4-triazole-3-sulfonamide 89517-96-4 1H-1,2,4-triazole-5-sulfonamide Not in list C2H4N4O2S C1=NNC(=N1)S(=O)(=O)N InChI=1S/C2H4N4O2S/c3-9(7,8)2-4-1-5-6-2/h1H,(H2,3,7,8)(H,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Poland Florasulam (RAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam 13Jan2015 2015 doi:10.2903/j.efsa.2015.3984
+Florasulam 604-488-1 145701-23-1 single chemical entity Component is a metabolite of the substance 1H-1,2,4-triazole-3-sulfonamide 89517-96-4 1H-1,2,4-triazole-5-sulfonamide Not in list C2H4N4O2S C1=NNC(=N1)S(=O)(=O)N InChI=1S/C2H4N4O2S/c3-9(7,8)2-4-1-5-6-2/h1H,(H2,3,7,8)(H,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Poland Florasulam (RAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam 13Jan2015 2015 doi:10.2903/j.efsa.2015.3984
+Florasulam 604-488-1 145701-23-1 single chemical entity Component is a metabolite of the substance 1H-1,2,4-triazole-3-sulfonamide 89517-96-4 1H-1,2,4-triazole-5-sulfonamide Not in list C2H4N4O2S C1=NNC(=N1)S(=O)(=O)N InChI=1S/C2H4N4O2S/c3-9(7,8)2-4-1-5-6-2/h1H,(H2,3,7,8)(H,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Poland Florasulam (RAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam 13Jan2015 2015 doi:10.2903/j.efsa.2015.3984
+Florasulam 604-488-1 145701-23-1 single chemical entity Component is a metabolite of the substance 1H-1,2,4-triazole-3-sulfonamide 89517-96-4 1H-1,2,4-triazole-5-sulfonamide Not in list C2H4N4O2S C1=NNC(=N1)S(=O)(=O)N InChI=1S/C2H4N4O2S/c3-9(7,8)2-4-1-5-6-2/h1H,(H2,3,7,8)(H,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Poland Florasulam (RAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam 13Jan2015 2015 doi:10.2903/j.efsa.2015.3984
+Florasulam 604-488-1 145701-23-1 single chemical entity Component is a metabolite of the substance 1H-1,2,4-triazole-3-sulfonamide 89517-96-4 1H-1,2,4-triazole-5-sulfonamide Not in list C2H4N4O2S C1=NNC(=N1)S(=O)(=O)N InChI=1S/C2H4N4O2S/c3-9(7,8)2-4-1-5-6-2/h1H,(H2,3,7,8)(H,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Poland Florasulam (RAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam 13Jan2015 2015 doi:10.2903/j.efsa.2015.3984
+Florasulam 604-488-1 145701-23-1 single chemical entity Component is a metabolite of the substance 1H-1,2,4-triazole-3-sulfonamide 89517-96-4 1H-1,2,4-triazole-5-sulfonamide Not in list C2H4N4O2S C1=NNC(=N1)S(=O)(=O)N InChI=1S/C2H4N4O2S/c3-9(7,8)2-4-1-5-6-2/h1H,(H2,3,7,8)(H,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Poland Florasulam (RAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam 13Jan2015 2015 doi:10.2903/j.efsa.2015.3984
+Florasulam 604-488-1 145701-23-1 single chemical entity Component is a metabolite of the substance 1H-1,2,4-triazole-3-sulfonamide 89517-96-4 1H-1,2,4-triazole-5-sulfonamide Not in list C2H4N4O2S C1=NNC(=N1)S(=O)(=O)N InChI=1S/C2H4N4O2S/c3-9(7,8)2-4-1-5-6-2/h1H,(H2,3,7,8)(H,4,5,6) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Poland Florasulam (RAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam 13Jan2015 2015 doi:10.2903/j.efsa.2015.3984
+Florasulam 604-488-1 145701-23-1 single chemical entity Component is a metabolite of the substance 1H-1,2,4-triazole-3-sulfonamide 89517-96-4 1H-1,2,4-triazole-5-sulfonamide Not in list C2H4N4O2S C1=NNC(=N1)S(=O)(=O)N InChI=1S/C2H4N4O2S/c3-9(7,8)2-4-1-5-6-2/h1H,(H2,3,7,8)(H,4,5,6) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Poland Florasulam (RAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam 13Jan2015 2015 doi:10.2903/j.efsa.2015.3984
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is a metabolite of the substance 2,4-dichlorophenol 204-429-6 120-83-2 2,4-dichlorophenol Not in list C6H4Cl2O C1=CC(=C(C=C1Cl)Cl)O InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No data Acceptable Hamster (as animal) CHO Not reported no data without Positive RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is a metabolite of the substance 2,4-dichlorophenol 204-429-6 120-83-2 2,4-dichlorophenol Not in list C6H4Cl2O C1=CC(=C(C=C1Cl)Cl)O InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No data Acceptable Hamster (as animal) CHO Not reported no data with Positive RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is a metabolite of the substance 2,4-dichlorophenol 204-429-6 120-83-2 2,4-dichlorophenol Not in list C6H4Cl2O C1=CC(=C(C=C1Cl)Cl)O InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No data Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data without Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is a metabolite of the substance 2,4-dichlorophenol 204-429-6 120-83-2 2,4-dichlorophenol Not in list C6H4Cl2O C1=CC(=C(C=C1Cl)Cl)O InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Rat (as animal) hepatocytes Not reported no data without Positive RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is a metabolite of the substance 2,4-dichlorophenol 204-429-6 120-83-2 2,4-dichlorophenol Not in list C6H4Cl2O C1=CC(=C(C=C1Cl)Cl)O InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is a metabolite of the substance 2,4-dichlorophenol 204-429-6 120-83-2 2,4-dichlorophenol Not in list C6H4Cl2O C1=CC(=C(C=C1Cl)Cl)O InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No data Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data without Positive no information RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is a metabolite of the substance 2,4-dichlorophenol 204-429-6 120-83-2 2,4-dichlorophenol Not in list C6H4Cl2O C1=CC(=C(C=C1Cl)Cl)O InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is a metabolite of the substance 2,4-dichlorophenol 204-429-6 120-83-2 2,4-dichlorophenol Not in list C6H4Cl2O C1=CC(=C(C=C1Cl)Cl)O InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is a metabolite of the substance 2,4-dichlorophenol 204-429-6 120-83-2 2,4-dichlorophenol Not in list C6H4Cl2O C1=CC(=C(C=C1Cl)Cl)O InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is a metabolite of the substance 2,4-dichlorophenol 204-429-6 120-83-2 2,4-dichlorophenol Not in list C6H4Cl2O C1=CC(=C(C=C1Cl)Cl)O InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is a metabolite of the substance 2,4-dichlorophenol 204-429-6 120-83-2 2,4-dichlorophenol Not in list C6H4Cl2O C1=CC(=C(C=C1Cl)Cl)O InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is a metabolite of the substance 2,4-dichlorophenol 204-429-6 120-83-2 2,4-dichlorophenol Not in list C6H4Cl2O C1=CC(=C(C=C1Cl)Cl)O InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is a metabolite of the substance 2,4-dichlorophenol 204-429-6 120-83-2 2,4-dichlorophenol Not in list C6H4Cl2O C1=CC(=C(C=C1Cl)Cl)O InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is a metabolite of the substance 2,4-dichlorophenol 204-429-6 120-83-2 2,4-dichlorophenol Not in list C6H4Cl2O C1=CC(=C(C=C1Cl)Cl)O InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is a metabolite of the substance 2,4-dichlorophenol 204-429-6 120-83-2 2,4-dichlorophenol Not in list C6H4Cl2O C1=CC(=C(C=C1Cl)Cl)O InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is a metabolite of the substance 2,4-dichlorophenol 204-429-6 120-83-2 2,4-dichlorophenol Not in list C6H4Cl2O C1=CC(=C(C=C1Cl)Cl)O InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No data Acceptable Hamster (as animal) CHO Not reported no data with Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is a metabolite of the substance 2,4-dichlorophenol 204-429-6 120-83-2 2,4-dichlorophenol Not in list C6H4Cl2O C1=CC(=C(C=C1Cl)Cl)O InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is a metabolite of the substance 2,4-dichlorophenol 204-429-6 120-83-2 2,4-dichlorophenol Not in list C6H4Cl2O C1=CC(=C(C=C1Cl)Cl)O InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is a metabolite of the substance 2,4-dichlorophenol 204-429-6 120-83-2 2,4-dichlorophenol Not in list C6H4Cl2O C1=CC(=C(C=C1Cl)Cl)O InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No data Acceptable Hamster (as animal) CHO Not reported no data without Positive RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is a metabolite of the substance 2,4-dichlorophenol 204-429-6 120-83-2 2,4-dichlorophenol Not in list C6H4Cl2O C1=CC(=C(C=C1Cl)Cl)O InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No data Acceptable Hamster (as animal) CHO Not reported no data without Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is a metabolite of the substance 2,4-dichlorophenol 204-429-6 120-83-2 2,4-dichlorophenol Not in list C6H4Cl2O C1=CC(=C(C=C1Cl)Cl)O InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is a metabolite of the substance 2,4-dichlorophenol 204-429-6 120-83-2 2,4-dichlorophenol Not in list C6H4Cl2O C1=CC(=C(C=C1Cl)Cl)O InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is a metabolite of the substance 2,4-dichlorophenol 204-429-6 120-83-2 2,4-dichlorophenol Not in list C6H4Cl2O C1=CC(=C(C=C1Cl)Cl)O InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No data Acceptable Hamster (as animal) CHO Not reported no data with Positive RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is a metabolite of the substance 2,4-dichlorophenol 204-429-6 120-83-2 2,4-dichlorophenol Not in list C6H4Cl2O C1=CC(=C(C=C1Cl)Cl)O InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is a metabolite of the substance Phenylbenzoquinone 363-03-1 2-phenylcyclohexa-2,5-diene-1,4-dione Not in list C12H8O2 C1=CC=C(C=C1)C2=CC(=O)C=CC2=O InChI=1S/C12H8O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian cell micronucleus test in vitro No guideline followed Not reported Not applicable Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data no data Negative RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+2-Phenylphenol 201-993-5 90-43-7 single chemical entity Component is a metabolite of the substance Phenylhydroquinone 1079-21-6 2-phenylbenzene-1,4-diol Not in list C12H10O2 C1=CC=C(C=C1)C2=C(C=CC(=C2)O)O InChI=1S/C12H10O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8,13-14H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian cell micronucleus test in vitro No guideline followed Not reported Not applicable Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data not applicable Positive RMS: Spain Ortho-phenylphenol 2007 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2-phenylphenol 06Mar2009 2009 doi:10.2903/j.efsa.2009.217r
+Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 single chemical entity Component is part of a group but not included in the group assessment Aluminium sulphate 233-135-0 10043-01-3 Dialuminum trisulfate Aluminium sulphate Al2O12S3 [O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3].[Al+3] InChI=1S/2Al.3H2O4S/c;;3*1-5(2,3)4/h;;3*(H2,1,2,3,4)/q2*+3;;;/p-6 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes without Negative RMS: Portugal Aluminium ammonium sulphate (Final Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate) 15Mar2012 2012 doi:10.2903/j.efsa.2012.2491
+Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 single chemical entity Component is part of a group but not included in the group assessment Aluminium sulphate 233-135-0 10043-01-3 Dialuminum trisulfate Aluminium sulphate Al2O12S3 [O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3].[Al+3] InChI=1S/2Al.3H2O4S/c;;3*1-5(2,3)4/h;;3*(H2,1,2,3,4)/q2*+3;;;/p-6 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes without Negative RMS: Portugal Aluminium ammonium sulphate (Final Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate) 15Mar2012 2012 doi:10.2903/j.efsa.2012.2491
+Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 single chemical entity Component is part of a group but not included in the group assessment Aluminium sulphate 233-135-0 10043-01-3 Dialuminum trisulfate Aluminium sulphate Al2O12S3 [O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3].[Al+3] InChI=1S/2Al.3H2O4S/c;;3*1-5(2,3)4/h;;3*(H2,1,2,3,4)/q2*+3;;;/p-6 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported no data no data Negative RMS: Portugal Aluminium ammonium sulphate (Final Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate) 15Mar2012 2012 doi:10.2903/j.efsa.2012.2491
+Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 single chemical entity Component is part of a group but not included in the group assessment Aluminium sulphate 233-135-0 10043-01-3 Dialuminum trisulfate Aluminium sulphate Al2O12S3 [O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3].[Al+3] InChI=1S/2Al.3H2O4S/c;;3*1-5(2,3)4/h;;3*(H2,1,2,3,4)/q2*+3;;;/p-6 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported no data no data Negative RMS: Portugal Aluminium ammonium sulphate (Final Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate) 15Mar2012 2012 doi:10.2903/j.efsa.2012.2491
+Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 single chemical entity Component is part of a group but not included in the group assessment Aluminium sulphate 233-135-0 10043-01-3 Dialuminum trisulfate Aluminium sulphate Al2O12S3 [O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3].[Al+3] InChI=1S/2Al.3H2O4S/c;;3*1-5(2,3)4/h;;3*(H2,1,2,3,4)/q2*+3;;;/p-6 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No data Acceptable Rat (as animal) Not reported no data no data Positive RMS: Portugal Aluminium ammonium sulphate (Final Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate) 15Mar2012 2012 doi:10.2903/j.efsa.2012.2491
+Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 single chemical entity Component is part of a group but not included in the group assessment Aluminium chloride 231-208-1 7446-70-0 trichloroalumane Not in list AlCl3 [Al](Cl)(Cl)Cl InChI=1S/Al.3ClH/h;3*1H/q+3;;;/p-3 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported no data no data Negative RMS: Portugal Aluminium ammonium sulphate (Final Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate) 15Mar2012 2012 doi:10.2903/j.efsa.2012.2491
+Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 single chemical entity Component is part of a group but not included in the group assessment Aluminium sulphate 233-135-0 10043-01-3 Dialuminum trisulfate Aluminium sulphate Al2O12S3 [O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3].[Al+3] InChI=1S/2Al.3H2O4S/c;;3*1-5(2,3)4/h;;3*(H2,1,2,3,4)/q2*+3;;;/p-6 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported no data no data Negative RMS: Portugal Aluminium ammonium sulphate (Final Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate) 15Mar2012 2012 doi:10.2903/j.efsa.2012.2491
+Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 single chemical entity Component is part of a group but not included in the group assessment Aluminium chloride 231-208-1 7446-70-0 trichloroalumane Not in list AlCl3 [Al](Cl)(Cl)Cl InChI=1S/Al.3ClH/h;3*1H/q+3;;;/p-3 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported no data no data Negative RMS: Portugal Aluminium ammonium sulphate (Final Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate) 15Mar2012 2012 doi:10.2903/j.efsa.2012.2491
+Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 single chemical entity Component is part of a group but not included in the group assessment Aluminium oxide 618-619-5 1344-28-1 dialuminum;oxygen(2-) Not in list Al2O3 [O-2].[O-2].[O-2].[Al+3].[Al+3] InChI=1S/2Al.3O/q2*+3;3*-2 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported no data no data Negative RMS: Portugal Aluminium ammonium sulphate (Final Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate) 15Mar2012 2012 doi:10.2903/j.efsa.2012.2491
+Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 single chemical entity Component is part of a group but not included in the group assessment Aluminium sulphate 233-135-0 10043-01-3 Dialuminum trisulfate Aluminium sulphate Al2O12S3 [O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3].[Al+3] InChI=1S/2Al.3H2O4S/c;;3*1-5(2,3)4/h;;3*(H2,1,2,3,4)/q2*+3;;;/p-6 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported no data no data Negative RMS: Portugal Aluminium ammonium sulphate (Final Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate) 15Mar2012 2012 doi:10.2903/j.efsa.2012.2491
+Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 single chemical entity Component is part of a group but not included in the group assessment Aluminium oxide 618-619-5 1344-28-1 dialuminum;oxygen(2-) Not in list Al2O3 [O-2].[O-2].[O-2].[Al+3].[Al+3] InChI=1S/2Al.3O/q2*+3;3*-2 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported no data no data Negative RMS: Portugal Aluminium ammonium sulphate (Final Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate) 15Mar2012 2012 doi:10.2903/j.efsa.2012.2491
+Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 single chemical entity Component is part of a group but not included in the group assessment Aluminium sulphate 233-135-0 10043-01-3 Dialuminum trisulfate Aluminium sulphate Al2O12S3 [O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3].[Al+3] InChI=1S/2Al.3H2O4S/c;;3*1-5(2,3)4/h;;3*(H2,1,2,3,4)/q2*+3;;;/p-6 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No data Acceptable House mouse (as animal) Not reported no data no data Positive RMS: Portugal Aluminium ammonium sulphate (Final Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate) 15Mar2012 2012 doi:10.2903/j.efsa.2012.2491
+Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 single chemical entity Component is part of a group but not included in the group assessment Aluminium sulphate 233-135-0 10043-01-3 Dialuminum trisulfate Aluminium sulphate Al2O12S3 [O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3].[Al+3] InChI=1S/2Al.3H2O4S/c;;3*1-5(2,3)4/h;;3*(H2,1,2,3,4)/q2*+3;;;/p-6 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No data Acceptable Hamster (as animal) Not reported no data no data Positive RMS: Portugal Aluminium ammonium sulphate (Final Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate) 15Mar2012 2012 doi:10.2903/j.efsa.2012.2491
+Aluminium ammonium sulphate dodecahydrate 232-055-3 7784-26-1 single chemical entity Component is part of a group but not included in the group assessment Aluminium chloride 231-208-1 7446-70-0 trichloroalumane Not in list AlCl3 [Al](Cl)(Cl)Cl InChI=1S/Al.3ClH/h;3*1H/q+3;;;/p-3 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No data Acceptable House mouse (as animal) Not reported No data intraperitoneal no data not applicable Positive RMS: Portugal Aluminium ammonium sulphate (Final Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate) 15Mar2012 2012 doi:10.2903/j.efsa.2012.2491
+Benfuracarb 82560-54-1 single chemical entity Component is identical to the substance Benfuracarb 82560-54-1 ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate Benfuracarb C20H30N2O5S CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration other in vitro No guideline available Not reported Not applicable Acceptable Saccharomyces cerevisiae (as organism) Not reported yes with Negative RMS: Belgium Benfuracarb 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is identical to the substance Benfuracarb 82560-54-1 ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate Benfuracarb C20H30N2O5S CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration other in vitro No guideline available Not reported Not applicable Acceptable Saccharomyces cerevisiae (as organism) Not reported yes without Negative RMS: Belgium Benfuracarb 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is identical to the substance Benfuracarb 82560-54-1 ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate Benfuracarb C20H30N2O5S CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female intraperitoneal 24.0000000000 h yes, concurrent vehicle not applicable Inconclusive no evidence RMS: Belgium Benfuracarb 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is identical to the substance Benfuracarb 82560-54-1 ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate Benfuracarb C20H30N2O5S CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female intraperitoneal 48.0000000000 h yes, concurrent vehicle not applicable Inconclusive no evidence RMS: Belgium Benfuracarb 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is identical to the substance Benfuracarb 82560-54-1 ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate Benfuracarb C20H30N2O5S CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female intraperitoneal 72.0000000000 h yes, concurrent vehicle not applicable Inconclusive no evidence RMS: Belgium Benfuracarb 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is identical to the substance Benfuracarb 82560-54-1 ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate Benfuracarb C20H30N2O5S CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Rat (as animal) Sprague-Dawley 10 Male/Female oral: gavage 6.0000000000 h yes not applicable Negative RMS: Belgium Benfuracarb 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is identical to the substance Benfuracarb 82560-54-1 ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate Benfuracarb C20H30N2O5S CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Rat (as animal) Sprague-Dawley 10 Male/Female oral: gavage 48.0000000000 h yes not applicable Negative RMS: Belgium Benfuracarb 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is identical to the substance Benfuracarb 82560-54-1 ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate Benfuracarb C20H30N2O5S CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Rat (as animal) Sprague-Dawley 10 Male/Female oral: gavage 24.0000000000 h yes not applicable Negative RMS: Belgium Benfuracarb 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance 2,2-dimethyl-2,3-dihydro-1-benzofuran-3,7-diol 17781-15-6 2,2-dimethyl-3H-1-benzofuran-3,7-diol Not in list C10H12O3 CC1(C(C2=C(O1)C(=CC=C2)O)O)C InChI=1S/C10H12O3/c1-10(2)9(12)6-4-3-5-7(11)8(6)13-10/h3-5,9,11-12H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data no data Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance 2,2-dimethyl-2,3-dihydro-1-benzofuran-3,7-diol 17781-15-6 2,2-dimethyl-3H-1-benzofuran-3,7-diol Not in list C10H12O3 CC1(C(C2=C(O1)C(=CC=C2)O)O)C InChI=1S/C10H12O3/c1-10(2)9(12)6-4-3-5-7(11)8(6)13-10/h3-5,9,11-12H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 102 Not reported no data no data Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance 2,2-dimethyl-2,3-dihydro-1-benzofuran-3,7-diol 17781-15-6 2,2-dimethyl-3H-1-benzofuran-3,7-diol Not in list C10H12O3 CC1(C(C2=C(O1)C(=CC=C2)O)O)C InChI=1S/C10H12O3/c1-10(2)9(12)6-4-3-5-7(11)8(6)13-10/h3-5,9,11-12H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data no data Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance 2,2-dimethyl-2,3-dihydro-1-benzofuran-3,7-diol 17781-15-6 2,2-dimethyl-3H-1-benzofuran-3,7-diol Not in list C10H12O3 CC1(C(C2=C(O1)C(=CC=C2)O)O)C InChI=1S/C10H12O3/c1-10(2)9(12)6-4-3-5-7(11)8(6)13-10/h3-5,9,11-12H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data no data Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benfuracarb 82560-54-1 single chemical entity Component is a metabolite of the substance 2,2-dimethyl-2,3-dihydro-1-benzofuran-3,7-diol 17781-15-6 2,2-dimethyl-3H-1-benzofuran-3,7-diol Not in list C10H12O3 CC1(C(C2=C(O1)C(=CC=C2)O)O)C InChI=1S/C10H12O3/c1-10(2)9(12)6-4-3-5-7(11)8(6)13-10/h3-5,9,11-12H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data no data Negative RMS: Belgium Benfuracarb (Original version July 2004, revised in August 2008) 2008 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance benfuracarb 08Apr2009 2009 doi:10.2903/j.efsa.2009.239r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Benthiavalicarb-isopropyl 177406-68-7 single chemical entity Component is identical to the substance Benthiavalicarb-isopropyl 177406-68-7 Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate Benthiavalicarb isopropyl C18H24FN3O3S C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Belgium Benthiavalicarb-isopropyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb 01Aug2007 2007 doi:10.2903/j.efsa.2007.107r
+Bromuconazole 116255-48-2 single chemical entity Component is a metabolite of the substance 1-{[(2RS)-2-(2,4-dichlorophenyl)-2,5-dihydrofuran-2-yl]methyl}-1H-1,2,4-triazole 1-{[2-(2,4-dichlorophenyl)-2,5-dihydrofuran-2-yl]methyl}-1H-1,2,4-triazole Not in list C13H11Cl2N3O Clc1cc(Cl)c(cc1)C2(C=CCO2)Cn3cncn3 InChI=1/C13H11Cl2N3O/c14-10-2-3-11(12(15)6-10)13(4-1-5-19-13)7-18-9-16-8-17-18/h1-4,6,8-9H,5,7H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Belgium Bromuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole 27Aug2010 2010 doi:10.2903/j.efsa.2010.1704
+Bromuconazole 116255-48-2 single chemical entity Component is a metabolite of the substance 1-{[(2RS)-2-(2,4-dichlorophenyl)-2,5-dihydrofuran-2-yl]methyl}-1H-1,2,4-triazole 1-{[2-(2,4-dichlorophenyl)-2,5-dihydrofuran-2-yl]methyl}-1H-1,2,4-triazole Not in list C13H11Cl2N3O Clc1cc(Cl)c(cc1)C2(C=CCO2)Cn3cncn3 InChI=1/C13H11Cl2N3O/c14-10-2-3-11(12(15)6-10)13(4-1-5-19-13)7-18-9-16-8-17-18/h1-4,6,8-9H,5,7H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Belgium Bromuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole 27Aug2010 2010 doi:10.2903/j.efsa.2010.1704
+Bromuconazole 116255-48-2 single chemical entity Component is a metabolite of the substance 1-{[(2RS)-2-(2,4-dichlorophenyl)-2,5-dihydrofuran-2-yl]methyl}-1H-1,2,4-triazole 1-{[2-(2,4-dichlorophenyl)-2,5-dihydrofuran-2-yl]methyl}-1H-1,2,4-triazole Not in list C13H11Cl2N3O Clc1cc(Cl)c(cc1)C2(C=CCO2)Cn3cncn3 InChI=1/C13H11Cl2N3O/c14-10-2-3-11(12(15)6-10)13(4-1-5-19-13)7-18-9-16-8-17-18/h1-4,6,8-9H,5,7H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium Bromuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole 27Aug2010 2010 doi:10.2903/j.efsa.2010.1704
+Bromuconazole 116255-48-2 single chemical entity Component is a metabolite of the substance 1-{[(2RS)-2-(2,4-dichlorophenyl)-2,5-dihydrofuran-2-yl]methyl}-1H-1,2,4-triazole 1-{[2-(2,4-dichlorophenyl)-2,5-dihydrofuran-2-yl]methyl}-1H-1,2,4-triazole Not in list C13H11Cl2N3O Clc1cc(Cl)c(cc1)C2(C=CCO2)Cn3cncn3 InChI=1/C13H11Cl2N3O/c14-10-2-3-11(12(15)6-10)13(4-1-5-19-13)7-18-9-16-8-17-18/h1-4,6,8-9H,5,7H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium Bromuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole 27Aug2010 2010 doi:10.2903/j.efsa.2010.1704
+Bromuconazole 116255-48-2 single chemical entity Component is a metabolite of the substance 1-{[(2RS)-2-(2,4-dichlorophenyl)-2,5-dihydrofuran-2-yl]methyl}-1H-1,2,4-triazole 1-{[2-(2,4-dichlorophenyl)-2,5-dihydrofuran-2-yl]methyl}-1H-1,2,4-triazole Not in list C13H11Cl2N3O Clc1cc(Cl)c(cc1)C2(C=CCO2)Cn3cncn3 InChI=1/C13H11Cl2N3O/c14-10-2-3-11(12(15)6-10)13(4-1-5-19-13)7-18-9-16-8-17-18/h1-4,6,8-9H,5,7H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium Bromuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole 27Aug2010 2010 doi:10.2903/j.efsa.2010.1704
+Bromuconazole 116255-48-2 single chemical entity Component is a metabolite of the substance 1-{[(2RS)-2-(2,4-dichlorophenyl)-2,5-dihydrofuran-2-yl]methyl}-1H-1,2,4-triazole 1-{[2-(2,4-dichlorophenyl)-2,5-dihydrofuran-2-yl]methyl}-1H-1,2,4-triazole Not in list C13H11Cl2N3O Clc1cc(Cl)c(cc1)C2(C=CCO2)Cn3cncn3 InChI=1/C13H11Cl2N3O/c14-10-2-3-11(12(15)6-10)13(4-1-5-19-13)7-18-9-16-8-17-18/h1-4,6,8-9H,5,7H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium Bromuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole 27Aug2010 2010 doi:10.2903/j.efsa.2010.1704
+Bromuconazole 116255-48-2 single chemical entity Component is a metabolite of the substance 1-{[(2RS)-2-(2,4-dichlorophenyl)-2,5-dihydrofuran-2-yl]methyl}-1H-1,2,4-triazole 1-{[2-(2,4-dichlorophenyl)-2,5-dihydrofuran-2-yl]methyl}-1H-1,2,4-triazole Not in list C13H11Cl2N3O Clc1cc(Cl)c(cc1)C2(C=CCO2)Cn3cncn3 InChI=1/C13H11Cl2N3O/c14-10-2-3-11(12(15)6-10)13(4-1-5-19-13)7-18-9-16-8-17-18/h1-4,6,8-9H,5,7H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium Bromuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole 27Aug2010 2010 doi:10.2903/j.efsa.2010.1704
+Bromuconazole 116255-48-2 single chemical entity Component is a metabolite of the substance 1-{[(2RS)-2-(2,4-dichlorophenyl)-2,5-dihydrofuran-2-yl]methyl}-1H-1,2,4-triazole 1-{[2-(2,4-dichlorophenyl)-2,5-dihydrofuran-2-yl]methyl}-1H-1,2,4-triazole Not in list C13H11Cl2N3O Clc1cc(Cl)c(cc1)C2(C=CCO2)Cn3cncn3 InChI=1/C13H11Cl2N3O/c14-10-2-3-11(12(15)6-10)13(4-1-5-19-13)7-18-9-16-8-17-18/h1-4,6,8-9H,5,7H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium Bromuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole 27Aug2010 2010 doi:10.2903/j.efsa.2010.1704
+Bromuconazole 116255-48-2 single chemical entity Component is a metabolite of the substance 1-{[(2RS)-2-(2,4-dichlorophenyl)-2,5-dihydrofuran-2-yl]methyl}-1H-1,2,4-triazole 1-{[2-(2,4-dichlorophenyl)-2,5-dihydrofuran-2-yl]methyl}-1H-1,2,4-triazole Not in list C13H11Cl2N3O Clc1cc(Cl)c(cc1)C2(C=CCO2)Cn3cncn3 InChI=1/C13H11Cl2N3O/c14-10-2-3-11(12(15)6-10)13(4-1-5-19-13)7-18-9-16-8-17-18/h1-4,6,8-9H,5,7H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium Bromuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole 27Aug2010 2010 doi:10.2903/j.efsa.2010.1704
+Bromuconazole 116255-48-2 single chemical entity Component is a metabolite of the substance 1-{[(2RS)-2-(2,4-dichlorophenyl)-2,5-dihydrofuran-2-yl]methyl}-1H-1,2,4-triazole 1-{[2-(2,4-dichlorophenyl)-2,5-dihydrofuran-2-yl]methyl}-1H-1,2,4-triazole Not in list C13H11Cl2N3O Clc1cc(Cl)c(cc1)C2(C=CCO2)Cn3cncn3 InChI=1/C13H11Cl2N3O/c14-10-2-3-11(12(15)6-10)13(4-1-5-19-13)7-18-9-16-8-17-18/h1-4,6,8-9H,5,7H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium Bromuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole 27Aug2010 2010 doi:10.2903/j.efsa.2010.1704
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is identical to the substance Carbosulfan 259-565-9 55285-14-8 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate Carbosulfan C20H32N2O3S CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable House mouse (as animal) ICR 10 Male/Female oral: gavage 42.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Belgium Carbosulfan (Addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Carbosulfan 259-565-9 55285-14-8 single chemical entity Component is identical to the substance Carbosulfan 259-565-9 55285-14-8 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate Carbosulfan C20H32N2O3S CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12 InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable House mouse (as animal) ICR 10 Male/Female oral: gavage 18.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Belgium Carbosulfan (Addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan 05Nov2009 2009 doi:10.2903/j.efsa.2009.1354
+Diquat 220-433-0 85-00-7 single chemical entity Component is identical to the substance Diquat 220-433-0 85-00-7 6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium Diquat C12H12N2+2 C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31 InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) Not reported Not reported no data no data Negative RMS: The United Kingdom Diquat 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diquat 27Nov2015 2015 doi:10.2903/j.efsa.2015.4308
+Diquat 220-433-0 85-00-7 single chemical entity Component is identical to the substance Diquat 220-433-0 85-00-7 6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium Diquat C12H12N2+2 C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31 InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Not reported No data oral: gavage no data not applicable Negative RMS: The United Kingdom Diquat 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance diquat 27Nov2015 2015 doi:10.2903/j.efsa.2015.4308
+Clofentezine 277-728-2 74115-24-5 single chemical entity Component is identical to the substance Clofentezine 277-728-2 74115-24-5 3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine Clofentezine C14H8Cl2N4 Clc3ccccc3c1nnc(nn1)c2ccccc2Cl InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The United Kingdom Clofentezine (Addendum1) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine 20Jul2009 2009 doi:10.2903/j.efsa.2009.269r
+Clofentezine 277-728-2 74115-24-5 single chemical entity Component is identical to the substance Clofentezine 277-728-2 74115-24-5 3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine Clofentezine C14H8Cl2N4 Clc3ccccc3c1nnc(nn1)c2ccccc2Cl InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The United Kingdom Clofentezine (Addendum1) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine 20Jul2009 2009 doi:10.2903/j.efsa.2009.269r
+Clofentezine 277-728-2 74115-24-5 single chemical entity Component is identical to the substance Clofentezine 277-728-2 74115-24-5 3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine Clofentezine C14H8Cl2N4 Clc3ccccc3c1nnc(nn1)c2ccccc2Cl InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The United Kingdom Clofentezine (Addendum1) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine 20Jul2009 2009 doi:10.2903/j.efsa.2009.269r
+Clofentezine 277-728-2 74115-24-5 single chemical entity Component is identical to the substance Clofentezine 277-728-2 74115-24-5 3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine Clofentezine C14H8Cl2N4 Clc3ccccc3c1nnc(nn1)c2ccccc2Cl InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes with Negative RMS: The United Kingdom Clofentezine (Addendum1) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine 20Jul2009 2009 doi:10.2903/j.efsa.2009.269r
+Clofentezine 277-728-2 74115-24-5 single chemical entity Component is identical to the substance Clofentezine 277-728-2 74115-24-5 3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine Clofentezine C14H8Cl2N4 Clc3ccccc3c1nnc(nn1)c2ccccc2Cl InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The United Kingdom Clofentezine (Addendum1) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine 20Jul2009 2009 doi:10.2903/j.efsa.2009.269r
+Clofentezine 277-728-2 74115-24-5 single chemical entity Component is identical to the substance Clofentezine 277-728-2 74115-24-5 3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine Clofentezine C14H8Cl2N4 Clc3ccccc3c1nnc(nn1)c2ccccc2Cl InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The United Kingdom Clofentezine (Addendum1) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine 20Jul2009 2009 doi:10.2903/j.efsa.2009.269r
+Clofentezine 277-728-2 74115-24-5 single chemical entity Component is identical to the substance Clofentezine 277-728-2 74115-24-5 3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine Clofentezine C14H8Cl2N4 Clc3ccccc3c1nnc(nn1)c2ccccc2Cl InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The United Kingdom Clofentezine (Addendum1) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine 20Jul2009 2009 doi:10.2903/j.efsa.2009.269r
+Clofentezine 277-728-2 74115-24-5 single chemical entity Component is identical to the substance Clofentezine 277-728-2 74115-24-5 3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine Clofentezine C14H8Cl2N4 Clc3ccccc3c1nnc(nn1)c2ccccc2Cl InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The United Kingdom Clofentezine (Addendum1) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine 20Jul2009 2009 doi:10.2903/j.efsa.2009.269r
+Clofentezine 277-728-2 74115-24-5 single chemical entity Component is identical to the substance Clofentezine 277-728-2 74115-24-5 3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine Clofentezine C14H8Cl2N4 Clc3ccccc3c1nnc(nn1)c2ccccc2Cl InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes without Negative RMS: The United Kingdom Clofentezine (Addendum1) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine 20Jul2009 2009 doi:10.2903/j.efsa.2009.269r
+Clofentezine 277-728-2 74115-24-5 single chemical entity Component is identical to the substance Clofentezine 277-728-2 74115-24-5 3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine Clofentezine C14H8Cl2N4 Clc3ccccc3c1nnc(nn1)c2ccccc2Cl InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The United Kingdom Clofentezine (Addendum1) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine 20Jul2009 2009 doi:10.2903/j.efsa.2009.269r
+Cyproconazole 94361-06-5 single chemical entity Component is a metabolite of the substance 5-(4-chloro-phenyl)-3,5-dihydroxy-4-methyl-6-[1,2,4]triazol-1-yl-hexanoic acid 5-(4-chlorophenyl)-3,5-dihydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)hexanoic acid Not in list C15H18ClN3O4 OC(Cn1cncn1)(C(C)C(O)CC(=O)O)c2ccc(Cl)cc2 InChI=1/C15H18ClN3O4/c1-10(13(20)6-14(21)22)15(23,7-19-9-17-8-18-19)11-2-4-12(16)5-3-11/h2-5,8-10,13,20,23H,6-7H2,1H3,(H,21,22) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Ireland Cyproconazole 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole 25Nov2010 2010 doi:10.2903/j.efsa.2010.1897
+Cyproconazole 94361-06-5 single chemical entity Component is a metabolite of the substance 5-(4-chloro-phenyl)-3,5-dihydroxy-4-methyl-6-[1,2,4]triazol-1-yl-hexanoic acid 5-(4-chlorophenyl)-3,5-dihydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)hexanoic acid Not in list C15H18ClN3O4 OC(Cn1cncn1)(C(C)C(O)CC(=O)O)c2ccc(Cl)cc2 InChI=1/C15H18ClN3O4/c1-10(13(20)6-14(21)22)15(23,7-19-9-17-8-18-19)11-2-4-12(16)5-3-11/h2-5,8-10,13,20,23H,6-7H2,1H3,(H,21,22) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male oral: unspecified 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Ireland Cyproconazole 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole 25Nov2010 2010 doi:10.2903/j.efsa.2010.1897
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1536 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other DNA damage and/or repair SOS/umu test in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) PQ37 Not reported yes without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other DNA damage and/or repair SOS/umu test in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) PQ37 Not reported yes with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other DNA damage and/or repair SOS/umu test in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) PQ37 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other DNA damage and/or repair SOS/umu test in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) PQ37 Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Salmonella typhimurium (as organism) Not reported Not reported no data no data Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported no data no data Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Salmonella typhimurium (as organism) Not reported Not reported no data no data Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) Not reported no data no data Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) Not reported no data no data Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro Equivalent or similar to OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay) No data Acceptable Saccharomyces cerevisiae (as organism) D3 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro Equivalent or similar to OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay) No data Acceptable Saccharomyces cerevisiae (as organism) D3 Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro Equivalent or similar to OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay) No data Acceptable Saccharomyces cerevisiae (as organism) D3 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro Equivalent or similar to OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay) No data Acceptable Saccharomyces cerevisiae (as organism) D3 Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro Equivalent or similar to OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay) No data Acceptable Saccharomyces cerevisiae (as organism) D3 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro Equivalent or similar to OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay) No data Acceptable Saccharomyces cerevisiae (as organism) D3 Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro Equivalent or similar to OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay) No data Acceptable Saccharomyces cerevisiae (as organism) D3 Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro Equivalent or similar to OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay) No data Acceptable Saccharomyces cerevisiae (as organism) D3 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro Equivalent or similar to OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay) No data Acceptable Saccharomyces cerevisiae (as organism) D3 Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro Equivalent or similar to OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay) No data Acceptable Saccharomyces cerevisiae (as organism) D3 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro Equivalent or similar to OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay) No data Acceptable Saccharomyces cerevisiae (as organism) D3 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro Equivalent or similar to OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay) No data Acceptable Saccharomyces cerevisiae (as organism) D3 Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro Equivalent or similar to OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay) No data Acceptable Saccharomyces cerevisiae (as organism) D3 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro Equivalent or similar to OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay) No data Acceptable Saccharomyces cerevisiae (as organism) D3 Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro Equivalent or similar to OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay) No data Acceptable Saccharomyces cerevisiae (as organism) D7 Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro Equivalent or similar to OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay) No data Acceptable Saccharomyces cerevisiae (as organism) D7 Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No data Acceptable House mouse (as animal) spleen cells Not reported no data no data Positive RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No data Acceptable Human (as organism) lymphocytes Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No data Acceptable Human (as organism) lymphocytes Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No data Acceptable House mouse (as animal) spleen cells Not reported no data no data Positive RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No data Acceptable Human (as organism) lymphocytes Not reported no data no data Positive RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No data Acceptable Hamster (as animal) CHO Not reported no data no data Positive RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No data Acceptable Human (as organism) fibroblast Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No data Acceptable Human (as organism) fibroblast Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No data Acceptable Human (as organism) fibroblast Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No data Acceptable Human (as organism) fibroblast Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No data Acceptable Human (as organism) fibroblast Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No data Acceptable Human (as organism) fibroblast Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No data Acceptable Human (as organism) fibroblast Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No data Acceptable Human (as organism) fibroblast Not reported no data with Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No data Acceptable Human (as organism) fibroblast Not reported no data with Positive RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vitro No guideline available Not reported Not applicable Acceptable Hamster (as animal) CHO Not reported no data no data Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vitro No guideline available Not reported Not applicable Acceptable Hamster (as animal) CHO Not reported no data no data Positive RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Human (as organism) Hep G2 human cell line Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Human (as organism) Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Human (as organism) Not reported no data without Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No data Acceptable Rat (as animal) Sprague-Dawley Male/Female oral: gavage no data not applicable Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No data Acceptable House mouse (as animal) Swiss No data intraperitoneal no data not applicable Positive RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other chromosome aberration other in vivo No guideline available Not reported Not applicable Acceptable Drosophila melanogaster (as animal) Not reported No data Not reported no data not applicable Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other genome mutation Drosophila SLRL test in vivo Equivalent or similar to OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster) No data Acceptable Drosophila melanogaster (as animal) Not reported No data Not reported no data not applicable Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other genome mutation Drosophila SLRL test in vivo Equivalent or similar to OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster) No data Acceptable Drosophila melanogaster (as animal) Not reported No data Not reported no data not applicable Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other genome mutation Drosophila SLRL test in vivo Equivalent or similar to OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster) No data Acceptable Drosophila melanogaster (as animal) Not reported No data Not reported no data not applicable Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other genome mutation Drosophila SLRL test in vivo Equivalent or similar to OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster) No data Acceptable Drosophila melanogaster (as animal) Not reported No data Not reported no data not applicable Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other genome mutation Drosophila SLRL test in vivo Equivalent or similar to OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster) No data Acceptable Drosophila melanogaster (as animal) Not reported No data Not reported no data not applicable Negative RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Dicamba 217-635-6 1918-00-9 single chemical entity Component is identical to the substance Dicamba 217-635-6 1918-00-9 3,6-dichloro-2-methoxybenzoic acid Dicamba C8H6Cl2O3 COc1c(Cl)ccc(Cl)c1C(=O)O InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12) organic compound Other Other DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable Rat (as animal) Sprague-Dawley Male Not reported no data not applicable Positive RMS: Denmark Dicamba (Revised draft assessment report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba 14Jan2011 2011 doi:10.2903/j.efsa.2011.1965
+Diflufenican 83164-33-4 single chemical entity Component is identical to the substance Diflufenican 83164-33-4 N-(2,4-difluorophenyl)-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxamide Diflufenican C19H11F5N2O2 C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)NC3=C(C=C(C=C3)F)F)C(F)(F)F InChI=1S/C19H11F5N2O2/c20-12-6-7-16(15(21)10-12)26-17(27)14-5-2-8-25-18(14)28-13-4-1-3-11(9-13)19(22,23)24/h1-10H,(H,26,27) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes without Negative RMS: the United Kingdom Diflufenican (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican 14Feb2008 2008 doi:10.2903/j.efsa.2008.122r
+Diflufenican 83164-33-4 single chemical entity Component is identical to the substance Diflufenican 83164-33-4 N-(2,4-difluorophenyl)-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxamide Diflufenican C19H11F5N2O2 C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)NC3=C(C=C(C=C3)F)F)C(F)(F)F InChI=1S/C19H11F5N2O2/c20-12-6-7-16(15(21)10-12)26-17(27)14-5-2-8-25-18(14)28-13-4-1-3-11(9-13)19(22,23)24/h1-10H,(H,26,27) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes with Negative RMS: the United Kingdom Diflufenican (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican 14Feb2008 2008 doi:10.2903/j.efsa.2008.122r
+Dodine 219-459-5 2439-10-3 single chemical entity Component is identical to the substance Dodine 219-459-5 2439-10-3 1-dodecylguanidine acetate Dodine C13H29N3.C2H4O2 CCCCCCCCCCCCNC(=N)N.CC(=O)O InChI=1/C13H29N3.C2H4O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-13(14)15;1-2(3)4/h2-12H2,1H3,(H4,14,15,16);1H3,(H,3,4) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Negative no information RMS: Portugal Dodine (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dodine 21Jun2010 2010 doi:10.2903/j.efsa.2010.1631
+Dodine 219-459-5 2439-10-3 single chemical entity Component is identical to the substance Dodine 219-459-5 2439-10-3 1-dodecylguanidine acetate Dodine C13H29N3.C2H4O2 CCCCCCCCCCCCNC(=N)N.CC(=O)O InChI=1/C13H29N3.C2H4O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-13(14)15;1-2(3)4/h2-12H2,1H3,(H4,14,15,16);1H3,(H,3,4) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative no information RMS: Portugal Dodine (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dodine 21Jun2010 2010 doi:10.2903/j.efsa.2010.1631
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is identical to the substance Thifensulfuron-methyl 616-673-4 79277-27-3 methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate Thifensulfuron-methyl C12H13N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) Not reported Not reported no data no data Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is identical to the substance Thifensulfuron-methyl 616-673-4 79277-27-3 methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate Thifensulfuron-methyl C12H13N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration mammalian germ cell cytogenetic assay in vivo Equivalent or similar to OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test) No data Acceptable House mouse (as animal) Not reported No data Not reported no data not applicable Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is identical to the substance Thifensulfuron-methyl 616-673-4 79277-27-3 methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate Thifensulfuron-methyl C12H13N5O6S2 CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable House mouse (as animal) Not reported No data Not reported no data not applicable Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No data Acceptable Hamster (as animal) CHO Not reported no data without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No data Acceptable Hamster (as animal) CHO Not reported no data with Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) Not reported Not reported no data no data Positive RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) Not reported Not reported no data without Positive RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA1530 Not reported no data without Positive RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) Not reported Not reported no data without Positive RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA1530 Not reported no data without Positive RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) Not reported Not reported no data no data Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) Not reported Not reported no data no data Positive RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Other Not reported Not reported no data without Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other gene mutation in vitro gene mutation assay in fungi in vitro No guideline available Not reported Not applicable Acceptable Aspergillus nidulans (as organism) Not reported Not reported no data without Positive RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) ICR No data oral: gavage no data not applicable Positive no evidence RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) ICR No data intraperitoneal no data not applicable Negative no evidence RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is part of a group but not included in the group assessment Thiophanate-methyl 245-740-7 23564-05-8 methyl N-[[2-(methoxycarbonylcarbamothioylamino)phenyl]carbamothioyl]carbamate Thiophanate-methyl C12H14N4O4S2 COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC InChI=1S/C12H14N4O4S2/c1-19-11(17)15-9(21)13-7-5-3-4-6-8(7)14-10(22)16-12(18)20-2/h3-6H,1-2H3,(H2,13,15,17,21)(H2,14,16,18,22) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian cell micronucleus test in vitro Equivalent or similar to OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test) No data Acceptable Human (as organism) lymphocytes Not reported no data without Positive RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is part of a group but not included in the group assessment Thiophanate-methyl 245-740-7 23564-05-8 methyl N-[[2-(methoxycarbonylcarbamothioylamino)phenyl]carbamothioyl]carbamate Thiophanate-methyl C12H14N4O4S2 COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC InChI=1S/C12H14N4O4S2/c1-19-11(17)15-9(21)13-7-5-3-4-6-8(7)14-10(22)16-12(18)20-2/h3-6H,1-2H3,(H2,13,15,17,21)(H2,14,16,18,22) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian cell micronucleus test in vitro Equivalent or similar to OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test) No data Acceptable Human (as organism) lymphocytes Not reported no data no data Positive RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other chromosome aberration in vitro mammalian cell micronucleus test in vitro Equivalent or similar to OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test) No data Acceptable Other Not reported no data no data Positive RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other chromosome aberration in vitro mammalian cell micronucleus test in vitro Equivalent or similar to OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test) No data Acceptable Human (as organism) lymphocytes Not reported no data no data Positive RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other chromosome aberration in vitro mammalian cell micronucleus test in vitro Equivalent or similar to OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test) No data Acceptable Human (as organism) lymphocytes Not reported yes no data Positive RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other chromosome aberration other in vivo No guideline available Not reported Not applicable Acceptable Hamster (as animal) Not reported Female oral: unspecified yes not applicable Positive RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable Rat (as animal) Not reported Male oral: unspecified 48.0000000000 h yes not applicable Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other chromosome aberration mammalian germ cell cytogenetic assay in vivo Equivalent or similar to OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test) No data Acceptable Rat (as animal) Not reported Male oral: unspecified yes not applicable Negative RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other chromosome aberration other in vivo No guideline available Not reported Not applicable Acceptable Rat (as animal) Sprague-Dawley Male Not reported 24.0000000000 h yes not applicable Positive RMS: Germany Carbendazim 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is identical to the substance Carbendazim 234-232-0 10605-21-7 methyl 1H-benzimidazol-2-ylcarbamate Carbendazim C9H9N3O2 N(C(=O)OC)C1=Nc2ccccc2N1 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) organic compound Other Other chromosome aberration other in vivo No guideline available Not reported No data Acceptable House mouse (as animal) Not reported 6 Male oral: gavage 28.0000000000 D yes, concurrent vehicle not applicable Negative RMS: Germany Carbendazim, Benomyl, Thiophanate-methyl (Addendum) 2002 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+2,4-D 202-361-1 94-75-7 single chemical entity Component is identical to the substance 2,4-D 202-361-1 94-75-7 (2,4-dichlorophenoxy)acetic acid 2,4-D C8H6Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCC(=O)O InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian cell micronucleus test in vitro Equivalent or similar to OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test) No data Acceptable Human (as organism) lymphocytes Not reported no data no data Negative RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-D 202-361-1 94-75-7 single chemical entity Component is identical to the substance 2,4-D 202-361-1 94-75-7 (2,4-dichlorophenoxy)acetic acid 2,4-D C8H6Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCC(=O)O InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) Not reported Male Not reported yes, concurrent vehicle not applicable Positive RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-D 202-361-1 94-75-7 single chemical entity Component is identical to the substance 2,4-D 202-361-1 94-75-7 (2,4-dichlorophenoxy)acetic acid 2,4-D C8H6Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCC(=O)O InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) Not reported Male Not reported yes, concurrent vehicle not applicable Positive RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-D 202-361-1 94-75-7 single chemical entity Component is identical to the substance 2,4-D 202-361-1 94-75-7 (2,4-dichlorophenoxy)acetic acid 2,4-D C8H6Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCC(=O)O InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair in vitro mammalian cell transformation assay in vitro No guideline available Not reported Not applicable Acceptable Hamster (as animal) embryo cells Not reported no data no data Positive RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-D 202-361-1 94-75-7 single chemical entity Component is part of a group assessment 2,4-D dimethyl amine salt 217-915-8 2008-39-1 2-(2,4-dichlorophenoxy)acetic acid;N-methylmethanamine Not in list C10H13Cl2NO3 CNC.C1=CC(=C(C=C1Cl)Cl)OCC(=O)O InChI=1S/C8H6Cl2O3.C2H7N/c9-5-1-2-7(6(10)3-5)13-4-8(11)12;1-3-2/h1-3H,4H2,(H,11,12);3H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No data Acceptable Human (as organism) Not reported yes no data Positive RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-D 202-361-1 94-75-7 single chemical entity Component is part of a group assessment 2,4-D dimethyl amine salt 217-915-8 2008-39-1 2-(2,4-dichlorophenoxy)acetic acid;N-methylmethanamine Not in list C10H13Cl2NO3 CNC.C1=CC(=C(C=C1Cl)Cl)OCC(=O)O InChI=1S/C8H6Cl2O3.C2H7N/c9-5-1-2-7(6(10)3-5)13-4-8(11)12;1-3-2/h1-3H,4H2,(H,11,12);3H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No data Acceptable Human (as organism) Not reported yes no data Negative RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-D 202-361-1 94-75-7 single chemical entity Component is identical to the substance 2,4-D 202-361-1 94-75-7 (2,4-dichlorophenoxy)acetic acid 2,4-D C8H6Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCC(=O)O InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) Yes Acceptable Human (as organism) Not reported yes no data Negative RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-D 202-361-1 94-75-7 single chemical entity Component is identical to the substance 2,4-D 202-361-1 94-75-7 (2,4-dichlorophenoxy)acetic acid 2,4-D C8H6Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCC(=O)O InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) Yes Acceptable Human (as organism) Not reported yes no data Positive RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-D 202-361-1 94-75-7 single chemical entity Component is identical to the substance 2,4-D 202-361-1 94-75-7 (2,4-dichlorophenoxy)acetic acid 2,4-D C8H6Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCC(=O)O InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vitro No guideline available Not reported Not applicable Acceptable Hamster (as animal) CHO Not reported no data no data Positive RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-D 202-361-1 94-75-7 single chemical entity Component is part of a group assessment 2,4-D dimethyl amine salt 217-915-8 2008-39-1 2-(2,4-dichlorophenoxy)acetic acid;N-methylmethanamine Not in list C10H13Cl2NO3 CNC.C1=CC(=C(C=C1Cl)Cl)OCC(=O)O InChI=1S/C8H6Cl2O3.C2H7N/c9-5-1-2-7(6(10)3-5)13-4-8(11)12;1-3-2/h1-3H,4H2,(H,11,12);3H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) Yes Acceptable Hamster (as animal) CHO Not reported yes no data Positive RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-D 202-361-1 94-75-7 single chemical entity Component is identical to the substance 2,4-D 202-361-1 94-75-7 (2,4-dichlorophenoxy)acetic acid 2,4-D C8H6Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCC(=O)O InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) Yes Acceptable Hamster (as animal) CHO Not reported no data no data Positive RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-D 202-361-1 94-75-7 single chemical entity Component is part of a group assessment 2,4-D dimethyl amine salt 217-915-8 2008-39-1 2-(2,4-dichlorophenoxy)acetic acid;N-methylmethanamine Not in list C10H13Cl2NO3 CNC.C1=CC(=C(C=C1Cl)Cl)OCC(=O)O InChI=1S/C8H6Cl2O3.C2H7N/c9-5-1-2-7(6(10)3-5)13-4-8(11)12;1-3-2/h1-3H,4H2,(H,11,12);3H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vitro No guideline available Not reported Not applicable Acceptable Hamster (as animal) CHO Not reported yes no data Positive RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-D 202-361-1 94-75-7 single chemical entity Component is identical to the substance 2,4-D 202-361-1 94-75-7 (2,4-dichlorophenoxy)acetic acid 2,4-D C8H6Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCC(=O)O InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Swiss No data oral: gavage 48.0000000000 h no data not applicable Positive RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-D 202-361-1 94-75-7 single chemical entity Component is identical to the substance 2,4-D 202-361-1 94-75-7 (2,4-dichlorophenoxy)acetic acid 2,4-D C8H6Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCC(=O)O InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Swiss No data oral: gavage 24.0000000000 h no data not applicable Positive RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-D 202-361-1 94-75-7 single chemical entity Component is identical to the substance 2,4-D 202-361-1 94-75-7 (2,4-dichlorophenoxy)acetic acid 2,4-D C8H6Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCC(=O)O InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Swiss No data oral: gavage 48.0000000000 h no data not applicable Positive RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-D 202-361-1 94-75-7 single chemical entity Component is identical to the substance 2,4-D 202-361-1 94-75-7 (2,4-dichlorophenoxy)acetic acid 2,4-D C8H6Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCC(=O)O InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Swiss No data oral: gavage 24.0000000000 h no data not applicable Positive RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-D 202-361-1 94-75-7 single chemical entity Component is identical to the substance 2,4-D 202-361-1 94-75-7 (2,4-dichlorophenoxy)acetic acid 2,4-D C8H6Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCC(=O)O InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vitro No guideline available Not reported Not applicable Acceptable Human (as organism) lymphocytes Not reported yes no data Positive RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-D 202-361-1 94-75-7 single chemical entity Component is identical to the substance 2,4-D 202-361-1 94-75-7 (2,4-dichlorophenoxy)acetic acid 2,4-D C8H6Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCC(=O)O InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No data Acceptable Human (as organism) lymphocytes Not reported yes no data Positive RMS: Greece - CoRMS: Poland 2,4-D (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D 11Sep2014 2014 doi:10.2903/j.efsa.2014.3812
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is a metabolite of the substance 2,4-dichlorophenol 204-429-6 120-83-2 2,4-dichlorophenol Not in list C6H4Cl2O C1=CC(=C(C=C1Cl)Cl)O InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is a metabolite of the substance 2,4-dichlorophenol 204-429-6 120-83-2 2,4-dichlorophenol Not in list C6H4Cl2O C1=CC(=C(C=C1Cl)Cl)O InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is a metabolite of the substance 2,4-dichlorophenol 204-429-6 120-83-2 2,4-dichlorophenol Not in list C6H4Cl2O C1=CC(=C(C=C1Cl)Cl)O InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is a metabolite of the substance 2,4-dichlorophenol 204-429-6 120-83-2 2,4-dichlorophenol Not in list C6H4Cl2O C1=CC(=C(C=C1Cl)Cl)O InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is a metabolite of the substance 2,4-dichlorophenol 204-429-6 120-83-2 2,4-dichlorophenol Not in list C6H4Cl2O C1=CC(=C(C=C1Cl)Cl)O InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is a metabolite of the substance 2,4-dichlorophenol 204-429-6 120-83-2 2,4-dichlorophenol Not in list C6H4Cl2O C1=CC(=C(C=C1Cl)Cl)O InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) Not reported no data with Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is a metabolite of the substance 2,4-dichlorophenol 204-429-6 120-83-2 2,4-dichlorophenol Not in list C6H4Cl2O C1=CC(=C(C=C1Cl)Cl)O InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is a metabolite of the substance 2,4-dichlorophenol 204-429-6 120-83-2 2,4-dichlorophenol Not in list C6H4Cl2O C1=CC(=C(C=C1Cl)Cl)O InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) Not reported no data with Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is a metabolite of the substance 2,4-dichlorophenol 204-429-6 120-83-2 2,4-dichlorophenol Not in list C6H4Cl2O C1=CC(=C(C=C1Cl)Cl)O InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) Not reported no data with Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is a metabolite of the substance 2,4-dichlorophenol 204-429-6 120-83-2 2,4-dichlorophenol Not in list C6H4Cl2O C1=CC(=C(C=C1Cl)Cl)O InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) Not reported no data with Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is identical to the substance 2,4-DB 202-366-9 94-82-6 4-(2,4-dichlorophenoxy)butanoic acid 2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB) C10H10Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is identical to the substance 2,4-DB 202-366-9 94-82-6 4-(2,4-dichlorophenoxy)butanoic acid 2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB) C10H10Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is identical to the substance 2,4-DB 202-366-9 94-82-6 4-(2,4-dichlorophenoxy)butanoic acid 2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB) C10H10Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is identical to the substance 2,4-DB 202-366-9 94-82-6 4-(2,4-dichlorophenoxy)butanoic acid 2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB) C10H10Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is identical to the substance 2,4-DB 202-366-9 94-82-6 4-(2,4-dichlorophenoxy)butanoic acid 2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB) C10H10Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is identical to the substance 2,4-DB 202-366-9 94-82-6 4-(2,4-dichlorophenoxy)butanoic acid 2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB) C10H10Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is identical to the substance 2,4-DB 202-366-9 94-82-6 4-(2,4-dichlorophenoxy)butanoic acid 2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB) C10H10Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is identical to the substance 2,4-DB 202-366-9 94-82-6 4-(2,4-dichlorophenoxy)butanoic acid 2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB) C10H10Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is identical to the substance 2,4-DB 202-366-9 94-82-6 4-(2,4-dichlorophenoxy)butanoic acid 2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB) C10H10Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is identical to the substance 2,4-DB 202-366-9 94-82-6 4-(2,4-dichlorophenoxy)butanoic acid 2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB) C10H10Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is identical to the substance 2,4-DB 202-366-9 94-82-6 4-(2,4-dichlorophenoxy)butanoic acid 2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB) C10H10Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is identical to the substance 2,4-DB 202-366-9 94-82-6 4-(2,4-dichlorophenoxy)butanoic acid 2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB) C10H10Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is identical to the substance 2,4-DB 202-366-9 94-82-6 4-(2,4-dichlorophenoxy)butanoic acid 2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB) C10H10Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is identical to the substance 2,4-DB 202-366-9 94-82-6 4-(2,4-dichlorophenoxy)butanoic acid 2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB) C10H10Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is identical to the substance 2,4-DB 202-366-9 94-82-6 4-(2,4-dichlorophenoxy)butanoic acid 2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB) C10H10Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+2,4-DB 202-366-9 94-82-6 single chemical entity Component is identical to the substance 2,4-DB 202-366-9 94-82-6 4-(2,4-dichlorophenoxy)butanoic acid 2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB) C10H10Cl2O3 C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian cell micronucleus test in vitro Equivalent or similar to OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test) Yes Acceptable Human (as organism) Not reported yes no data Negative RMS: Belgium - CoRMS: Greece 2,4-DB 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance 2,4-DB 31May2016 2016 doi:10.2903/j.efsa.2016.4500
+Azoxystrobin 131860-33-8 single chemical entity Component is a metabolite of the substance 2-[6-(2-cyanophenoxy)pyrimidin-4-yloxy]benzoic acid 2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}benzoic acid Not in list C18H11N3O4 O=C(O)c3ccccc3Oc2cc(Oc1ccccc1C#N)ncn2 InChI=1/C18H11N3O4/c19-10-12-5-1-3-7-14(12)24-16-9-17(21-11-20-16)25-15-8-4-2-6-13(15)18(22)23/h1-9,11H,(H,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: The United Kingdom - CoRMS: Czech Republic Azoxystrobin (Final Addendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin 15Apr2010 2010 doi:10.2903/j.efsa.2010.1542
+Azoxystrobin 131860-33-8 single chemical entity Component is a metabolite of the substance 2-[6-(2-cyanophenoxy)pyrimidin-4-yloxy]benzoic acid 2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}benzoic acid Not in list C18H11N3O4 O=C(O)c3ccccc3Oc2cc(Oc1ccccc1C#N)ncn2 InChI=1/C18H11N3O4/c19-10-12-5-1-3-7-14(12)24-16-9-17(21-11-20-16)25-15-8-4-2-6-13(15)18(22)23/h1-9,11H,(H,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: The United Kingdom - CoRMS: Czech Republic Azoxystrobin (Final Addendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin 15Apr2010 2010 doi:10.2903/j.efsa.2010.1542
+Azoxystrobin 131860-33-8 single chemical entity Component is a metabolite of the substance 2-[6-(2-cyanophenoxy)pyrimidin-4-yloxy]benzoic acid 2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}benzoic acid Not in list C18H11N3O4 O=C(O)c3ccccc3Oc2cc(Oc1ccccc1C#N)ncn2 InChI=1/C18H11N3O4/c19-10-12-5-1-3-7-14(12)24-16-9-17(21-11-20-16)25-15-8-4-2-6-13(15)18(22)23/h1-9,11H,(H,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: The United Kingdom - CoRMS: Czech Republic Azoxystrobin (Final Addendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin 15Apr2010 2010 doi:10.2903/j.efsa.2010.1542
+Azoxystrobin 131860-33-8 single chemical entity Component is a metabolite of the substance 2-[6-(2-cyanophenoxy)pyrimidin-4-yloxy]benzoic acid 2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}benzoic acid Not in list C18H11N3O4 O=C(O)c3ccccc3Oc2cc(Oc1ccccc1C#N)ncn2 InChI=1/C18H11N3O4/c19-10-12-5-1-3-7-14(12)24-16-9-17(21-11-20-16)25-15-8-4-2-6-13(15)18(22)23/h1-9,11H,(H,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: The United Kingdom - CoRMS: Czech Republic Azoxystrobin (Final Addendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin 15Apr2010 2010 doi:10.2903/j.efsa.2010.1542
+Azoxystrobin 131860-33-8 single chemical entity Component is a metabolite of the substance 2-[6-(2-cyanophenoxy)pyrimidin-4-yloxy]benzoic acid 2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}benzoic acid Not in list C18H11N3O4 O=C(O)c3ccccc3Oc2cc(Oc1ccccc1C#N)ncn2 InChI=1/C18H11N3O4/c19-10-12-5-1-3-7-14(12)24-16-9-17(21-11-20-16)25-15-8-4-2-6-13(15)18(22)23/h1-9,11H,(H,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported no data with Negative RMS: The United Kingdom - CoRMS: Czech Republic Azoxystrobin (Final Addendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin 15Apr2010 2010 doi:10.2903/j.efsa.2010.1542
+Azoxystrobin 131860-33-8 single chemical entity Component is a metabolite of the substance 2-[6-(2-cyanophenoxy)pyrimidin-4-yloxy]benzoic acid 2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}benzoic acid Not in list C18H11N3O4 O=C(O)c3ccccc3Oc2cc(Oc1ccccc1C#N)ncn2 InChI=1/C18H11N3O4/c19-10-12-5-1-3-7-14(12)24-16-9-17(21-11-20-16)25-15-8-4-2-6-13(15)18(22)23/h1-9,11H,(H,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: The United Kingdom - CoRMS: Czech Republic Azoxystrobin (Final Addendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin 15Apr2010 2010 doi:10.2903/j.efsa.2010.1542
+Azoxystrobin 131860-33-8 single chemical entity Component is a metabolite of the substance 2-[6-(2-cyanophenoxy)pyrimidin-4-yloxy]benzoic acid 2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}benzoic acid Not in list C18H11N3O4 O=C(O)c3ccccc3Oc2cc(Oc1ccccc1C#N)ncn2 InChI=1/C18H11N3O4/c19-10-12-5-1-3-7-14(12)24-16-9-17(21-11-20-16)25-15-8-4-2-6-13(15)18(22)23/h1-9,11H,(H,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: The United Kingdom - CoRMS: Czech Republic Azoxystrobin (Final Addendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin 15Apr2010 2010 doi:10.2903/j.efsa.2010.1542
+Azoxystrobin 131860-33-8 single chemical entity Component is a metabolite of the substance 2-[6-(2-cyanophenoxy)pyrimidin-4-yloxy]benzoic acid 2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}benzoic acid Not in list C18H11N3O4 O=C(O)c3ccccc3Oc2cc(Oc1ccccc1C#N)ncn2 InChI=1/C18H11N3O4/c19-10-12-5-1-3-7-14(12)24-16-9-17(21-11-20-16)25-15-8-4-2-6-13(15)18(22)23/h1-9,11H,(H,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: The United Kingdom - CoRMS: Czech Republic Azoxystrobin (Final Addendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin 15Apr2010 2010 doi:10.2903/j.efsa.2010.1542
+Azoxystrobin 131860-33-8 single chemical entity Component is a metabolite of the substance 2-[6-(2-cyanophenoxy)pyrimidin-4-yloxy]benzoic acid 2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}benzoic acid Not in list C18H11N3O4 O=C(O)c3ccccc3Oc2cc(Oc1ccccc1C#N)ncn2 InChI=1/C18H11N3O4/c19-10-12-5-1-3-7-14(12)24-16-9-17(21-11-20-16)25-15-8-4-2-6-13(15)18(22)23/h1-9,11H,(H,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: The United Kingdom - CoRMS: Czech Republic Azoxystrobin (Final Addendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin 15Apr2010 2010 doi:10.2903/j.efsa.2010.1542
+Azoxystrobin 131860-33-8 single chemical entity Component is a metabolite of the substance 2-[6-(2-cyanophenoxy)pyrimidin-4-yloxy]benzoic acid 2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}benzoic acid Not in list C18H11N3O4 O=C(O)c3ccccc3Oc2cc(Oc1ccccc1C#N)ncn2 InChI=1/C18H11N3O4/c19-10-12-5-1-3-7-14(12)24-16-9-17(21-11-20-16)25-15-8-4-2-6-13(15)18(22)23/h1-9,11H,(H,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: The United Kingdom - CoRMS: Czech Republic Azoxystrobin (Final Addendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin 15Apr2010 2010 doi:10.2903/j.efsa.2010.1542
+Azoxystrobin 131860-33-8 single chemical entity Component is a metabolite of the substance 2-[6-(2-cyanophenoxy)pyrimidin-4-yloxy]benzoic acid 2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}benzoic acid Not in list C18H11N3O4 O=C(O)c3ccccc3Oc2cc(Oc1ccccc1C#N)ncn2 InChI=1/C18H11N3O4/c19-10-12-5-1-3-7-14(12)24-16-9-17(21-11-20-16)25-15-8-4-2-6-13(15)18(22)23/h1-9,11H,(H,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported no data without Negative RMS: The United Kingdom - CoRMS: Czech Republic Azoxystrobin (Final Addendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin 15Apr2010 2010 doi:10.2903/j.efsa.2010.1542
+Azoxystrobin 131860-33-8 single chemical entity Component is a metabolite of the substance 2-[6-(2-cyanophenoxy)pyrimidin-4-yloxy]benzoic acid 2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}benzoic acid Not in list C18H11N3O4 O=C(O)c3ccccc3Oc2cc(Oc1ccccc1C#N)ncn2 InChI=1/C18H11N3O4/c19-10-12-5-1-3-7-14(12)24-16-9-17(21-11-20-16)25-15-8-4-2-6-13(15)18(22)23/h1-9,11H,(H,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: The United Kingdom - CoRMS: Czech Republic Azoxystrobin (Final Addendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin 15Apr2010 2010 doi:10.2903/j.efsa.2010.1542
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance Methyl N-(malonyl)-N-(2,6-xylyl)-D-alaninate 3-{(2,6-dimethylphenyl)[(2R)-1-methoxy-1-oxopropan-2-yl]amino}-3-oxopropanoic acid Not in list C15H19NO5 C[C@@H](N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC InChI=1/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)/t11-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl-M (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance Methyl N-(malonyl)-N-(2,6-xylyl)-D-alaninate 3-{(2,6-dimethylphenyl)[(2R)-1-methoxy-1-oxopropan-2-yl]amino}-3-oxopropanoic acid Not in list C15H19NO5 C[C@@H](N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC InChI=1/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)/t11-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl-M (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance Methyl N-(malonyl)-N-(2,6-xylyl)-D-alaninate 3-{(2,6-dimethylphenyl)[(2R)-1-methoxy-1-oxopropan-2-yl]amino}-3-oxopropanoic acid Not in list C15H19NO5 C[C@@H](N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC InChI=1/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)/t11-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl-M (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance Methyl N-(malonyl)-N-(2,6-xylyl)-D-alaninate 3-{(2,6-dimethylphenyl)[(2R)-1-methoxy-1-oxopropan-2-yl]amino}-3-oxopropanoic acid Not in list C15H19NO5 C[C@@H](N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC InChI=1/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)/t11-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl-M (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance Methyl N-(malonyl)-N-(2,6-xylyl)-D-alaninate 3-{(2,6-dimethylphenyl)[(2R)-1-methoxy-1-oxopropan-2-yl]amino}-3-oxopropanoic acid Not in list C15H19NO5 C[C@@H](N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC InChI=1/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)/t11-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl-M (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance Methyl N-(malonyl)-N-(2,6-xylyl)-D-alaninate 3-{(2,6-dimethylphenyl)[(2R)-1-methoxy-1-oxopropan-2-yl]amino}-3-oxopropanoic acid Not in list C15H19NO5 C[C@@H](N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC InChI=1/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)/t11-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl-M (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance Methyl N-(malonyl)-N-(2,6-xylyl)-D-alaninate 3-{(2,6-dimethylphenyl)[(2R)-1-methoxy-1-oxopropan-2-yl]amino}-3-oxopropanoic acid Not in list C15H19NO5 C[C@@H](N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC InChI=1/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)/t11-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl-M (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance Methyl N-(malonyl)-N-(2,6-xylyl)-D-alaninate 3-{(2,6-dimethylphenyl)[(2R)-1-methoxy-1-oxopropan-2-yl]amino}-3-oxopropanoic acid Not in list C15H19NO5 C[C@@H](N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC InChI=1/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)/t11-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl-M (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance Methyl N-(malonyl)-N-(2,6-xylyl)-D-alaninate 3-{(2,6-dimethylphenyl)[(2R)-1-methoxy-1-oxopropan-2-yl]amino}-3-oxopropanoic acid Not in list C15H19NO5 C[C@@H](N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC InChI=1/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)/t11-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl-M (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance Methyl N-(malonyl)-N-(2,6-xylyl)-D-alaninate 3-{(2,6-dimethylphenyl)[(2R)-1-methoxy-1-oxopropan-2-yl]amino}-3-oxopropanoic acid Not in list C15H19NO5 C[C@@H](N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC InChI=1/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)/t11-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl-M (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance 2-{(Carboxyacetyl)[(2RS)-1-methoxy-1-oxo-2-propanyl]amino}-3-methylbenzoic acid 2-[(carboxyacetyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-methylbenzoic acid Not in list CC(N(C(=O)CC(=O)O)c1c(C)cccc1C(=O)O)C(=O)OC InChI=1/C15H17NO7/c1-8-5-4-6-10(14(20)21)13(8)16(9(2)15(22)23-3)11(17)7-12(18)19/h4-6,9H,7H2,1-3H3,(H,18,19)(H,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl-M (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance 2-{(Carboxyacetyl)[(2RS)-1-methoxy-1-oxo-2-propanyl]amino}-3-methylbenzoic acid 2-[(carboxyacetyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-methylbenzoic acid Not in list CC(N(C(=O)CC(=O)O)c1c(C)cccc1C(=O)O)C(=O)OC InChI=1/C15H17NO7/c1-8-5-4-6-10(14(20)21)13(8)16(9(2)15(22)23-3)11(17)7-12(18)19/h4-6,9H,7H2,1-3H3,(H,18,19)(H,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl-M (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance 2-{(Carboxyacetyl)[(2RS)-1-methoxy-1-oxo-2-propanyl]amino}-3-methylbenzoic acid 2-[(carboxyacetyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-methylbenzoic acid Not in list CC(N(C(=O)CC(=O)O)c1c(C)cccc1C(=O)O)C(=O)OC InChI=1/C15H17NO7/c1-8-5-4-6-10(14(20)21)13(8)16(9(2)15(22)23-3)11(17)7-12(18)19/h4-6,9H,7H2,1-3H3,(H,18,19)(H,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl-M (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance 2-{(Carboxyacetyl)[(2RS)-1-methoxy-1-oxo-2-propanyl]amino}-3-methylbenzoic acid 2-[(carboxyacetyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-methylbenzoic acid Not in list CC(N(C(=O)CC(=O)O)c1c(C)cccc1C(=O)O)C(=O)OC InChI=1/C15H17NO7/c1-8-5-4-6-10(14(20)21)13(8)16(9(2)15(22)23-3)11(17)7-12(18)19/h4-6,9H,7H2,1-3H3,(H,18,19)(H,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl-M (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance 2-{(Carboxyacetyl)[(2RS)-1-methoxy-1-oxo-2-propanyl]amino}-3-methylbenzoic acid 2-[(carboxyacetyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-methylbenzoic acid Not in list CC(N(C(=O)CC(=O)O)c1c(C)cccc1C(=O)O)C(=O)OC InChI=1/C15H17NO7/c1-8-5-4-6-10(14(20)21)13(8)16(9(2)15(22)23-3)11(17)7-12(18)19/h4-6,9H,7H2,1-3H3,(H,18,19)(H,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl-M (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance 2-{(Carboxyacetyl)[(2RS)-1-methoxy-1-oxo-2-propanyl]amino}-3-methylbenzoic acid 2-[(carboxyacetyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-methylbenzoic acid Not in list CC(N(C(=O)CC(=O)O)c1c(C)cccc1C(=O)O)C(=O)OC InChI=1/C15H17NO7/c1-8-5-4-6-10(14(20)21)13(8)16(9(2)15(22)23-3)11(17)7-12(18)19/h4-6,9H,7H2,1-3H3,(H,18,19)(H,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl-M (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance 2-{(Carboxyacetyl)[(2RS)-1-methoxy-1-oxo-2-propanyl]amino}-3-methylbenzoic acid 2-[(carboxyacetyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-methylbenzoic acid Not in list CC(N(C(=O)CC(=O)O)c1c(C)cccc1C(=O)O)C(=O)OC InChI=1/C15H17NO7/c1-8-5-4-6-10(14(20)21)13(8)16(9(2)15(22)23-3)11(17)7-12(18)19/h4-6,9H,7H2,1-3H3,(H,18,19)(H,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl-M (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance 2-{(Carboxyacetyl)[(2RS)-1-methoxy-1-oxo-2-propanyl]amino}-3-methylbenzoic acid 2-[(carboxyacetyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-methylbenzoic acid Not in list CC(N(C(=O)CC(=O)O)c1c(C)cccc1C(=O)O)C(=O)OC InChI=1/C15H17NO7/c1-8-5-4-6-10(14(20)21)13(8)16(9(2)15(22)23-3)11(17)7-12(18)19/h4-6,9H,7H2,1-3H3,(H,18,19)(H,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl-M (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance 2-{(Carboxyacetyl)[(2RS)-1-methoxy-1-oxo-2-propanyl]amino}-3-methylbenzoic acid 2-[(carboxyacetyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-methylbenzoic acid Not in list CC(N(C(=O)CC(=O)O)c1c(C)cccc1C(=O)O)C(=O)OC InChI=1/C15H17NO7/c1-8-5-4-6-10(14(20)21)13(8)16(9(2)15(22)23-3)11(17)7-12(18)19/h4-6,9H,7H2,1-3H3,(H,18,19)(H,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl-M (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance 2-{(Carboxyacetyl)[(2RS)-1-methoxy-1-oxo-2-propanyl]amino}-3-methylbenzoic acid 2-[(carboxyacetyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-methylbenzoic acid Not in list CC(N(C(=O)CC(=O)O)c1c(C)cccc1C(=O)O)C(=O)OC InChI=1/C15H17NO7/c1-8-5-4-6-10(14(20)21)13(8)16(9(2)15(22)23-3)11(17)7-12(18)19/h4-6,9H,7H2,1-3H3,(H,18,19)(H,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl-M (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance 2-{(Carboxyacetyl)[(1RS)-1-carboxyethyl]amino}-3-methylbenzoic acid 2-[(carboxyacetyl)(1-carboxyethyl)amino]-3-methylbenzoic acid Not in list C14H15NO7 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C(=O)O)C(=O)O InChI=1S/C14H15NO7/c1-7-4-3-5-9(14(21)22)12(7)15(8(2)13(19)20)10(16)6-11(17)18/h3-5,8H,6H2,1-2H3,(H,17,18)(H,19,20)(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl-M (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance 2-{(Carboxyacetyl)[(1RS)-1-carboxyethyl]amino}-3-methylbenzoic acid 2-[(carboxyacetyl)(1-carboxyethyl)amino]-3-methylbenzoic acid Not in list C14H15NO7 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C(=O)O)C(=O)O InChI=1S/C14H15NO7/c1-7-4-3-5-9(14(21)22)12(7)15(8(2)13(19)20)10(16)6-11(17)18/h3-5,8H,6H2,1-2H3,(H,17,18)(H,19,20)(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl-M (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance 2-{(Carboxyacetyl)[(1RS)-1-carboxyethyl]amino}-3-methylbenzoic acid 2-[(carboxyacetyl)(1-carboxyethyl)amino]-3-methylbenzoic acid Not in list C14H15NO7 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C(=O)O)C(=O)O InChI=1S/C14H15NO7/c1-7-4-3-5-9(14(21)22)12(7)15(8(2)13(19)20)10(16)6-11(17)18/h3-5,8H,6H2,1-2H3,(H,17,18)(H,19,20)(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl-M (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance 2-{(Carboxyacetyl)[(1RS)-1-carboxyethyl]amino}-3-methylbenzoic acid 2-[(carboxyacetyl)(1-carboxyethyl)amino]-3-methylbenzoic acid Not in list C14H15NO7 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C(=O)O)C(=O)O InChI=1S/C14H15NO7/c1-7-4-3-5-9(14(21)22)12(7)15(8(2)13(19)20)10(16)6-11(17)18/h3-5,8H,6H2,1-2H3,(H,17,18)(H,19,20)(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl-M (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance 2-{(Carboxyacetyl)[(1RS)-1-carboxyethyl]amino}-3-methylbenzoic acid 2-[(carboxyacetyl)(1-carboxyethyl)amino]-3-methylbenzoic acid Not in list C14H15NO7 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C(=O)O)C(=O)O InChI=1S/C14H15NO7/c1-7-4-3-5-9(14(21)22)12(7)15(8(2)13(19)20)10(16)6-11(17)18/h3-5,8H,6H2,1-2H3,(H,17,18)(H,19,20)(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl-M (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance 2-{(Carboxyacetyl)[(1RS)-1-carboxyethyl]amino}-3-methylbenzoic acid 2-[(carboxyacetyl)(1-carboxyethyl)amino]-3-methylbenzoic acid Not in list C14H15NO7 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C(=O)O)C(=O)O InChI=1S/C14H15NO7/c1-7-4-3-5-9(14(21)22)12(7)15(8(2)13(19)20)10(16)6-11(17)18/h3-5,8H,6H2,1-2H3,(H,17,18)(H,19,20)(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl-M (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance 2-{(Carboxyacetyl)[(1RS)-1-carboxyethyl]amino}-3-methylbenzoic acid 2-[(carboxyacetyl)(1-carboxyethyl)amino]-3-methylbenzoic acid Not in list C14H15NO7 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C(=O)O)C(=O)O InChI=1S/C14H15NO7/c1-7-4-3-5-9(14(21)22)12(7)15(8(2)13(19)20)10(16)6-11(17)18/h3-5,8H,6H2,1-2H3,(H,17,18)(H,19,20)(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl-M (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance 2-{(Carboxyacetyl)[(1RS)-1-carboxyethyl]amino}-3-methylbenzoic acid 2-[(carboxyacetyl)(1-carboxyethyl)amino]-3-methylbenzoic acid Not in list C14H15NO7 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C(=O)O)C(=O)O InChI=1S/C14H15NO7/c1-7-4-3-5-9(14(21)22)12(7)15(8(2)13(19)20)10(16)6-11(17)18/h3-5,8H,6H2,1-2H3,(H,17,18)(H,19,20)(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl-M (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance 2-{(Carboxyacetyl)[(1RS)-1-carboxyethyl]amino}-3-methylbenzoic acid 2-[(carboxyacetyl)(1-carboxyethyl)amino]-3-methylbenzoic acid Not in list C14H15NO7 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C(=O)O)C(=O)O InChI=1S/C14H15NO7/c1-7-4-3-5-9(14(21)22)12(7)15(8(2)13(19)20)10(16)6-11(17)18/h3-5,8H,6H2,1-2H3,(H,17,18)(H,19,20)(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl-M (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance 2-{(Carboxyacetyl)[(1RS)-1-carboxyethyl]amino}-3-methylbenzoic acid 2-[(carboxyacetyl)(1-carboxyethyl)amino]-3-methylbenzoic acid Not in list C14H15NO7 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C(=O)O)C(=O)O InChI=1S/C14H15NO7/c1-7-4-3-5-9(14(21)22)12(7)15(8(2)13(19)20)10(16)6-11(17)18/h3-5,8H,6H2,1-2H3,(H,17,18)(H,19,20)(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl-M (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance Methyl N-(malonyl)-N-(2,6-xylyl)-D-alaninate 3-{(2,6-dimethylphenyl)[(2R)-1-methoxy-1-oxopropan-2-yl]amino}-3-oxopropanoic acid Not in list C15H19NO5 C[C@@H](N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC InChI=1/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)/t11-/m1/s1 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl-M (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance Methyl N-(malonyl)-N-(2,6-xylyl)-D-alaninate 3-{(2,6-dimethylphenyl)[(2R)-1-methoxy-1-oxopropan-2-yl]amino}-3-oxopropanoic acid Not in list C15H19NO5 C[C@@H](N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC InChI=1/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)/t11-/m1/s1 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl-M (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance 2-{(Carboxyacetyl)[(2RS)-1-methoxy-1-oxo-2-propanyl]amino}-3-methylbenzoic acid 2-[(carboxyacetyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-methylbenzoic acid Not in list CC(N(C(=O)CC(=O)O)c1c(C)cccc1C(=O)O)C(=O)OC InChI=1/C15H17NO7/c1-8-5-4-6-10(14(20)21)13(8)16(9(2)15(22)23-3)11(17)7-12(18)19/h4-6,9H,7H2,1-3H3,(H,18,19)(H,20,21) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl-M (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance 2-{(Carboxyacetyl)[(2RS)-1-methoxy-1-oxo-2-propanyl]amino}-3-methylbenzoic acid 2-[(carboxyacetyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-methylbenzoic acid Not in list CC(N(C(=O)CC(=O)O)c1c(C)cccc1C(=O)O)C(=O)OC InChI=1/C15H17NO7/c1-8-5-4-6-10(14(20)21)13(8)16(9(2)15(22)23-3)11(17)7-12(18)19/h4-6,9H,7H2,1-3H3,(H,18,19)(H,20,21) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl-M (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance 2-{(Carboxyacetyl)[(1RS)-1-carboxyethyl]amino}-3-methylbenzoic acid 2-[(carboxyacetyl)(1-carboxyethyl)amino]-3-methylbenzoic acid Not in list C14H15NO7 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C(=O)O)C(=O)O InChI=1S/C14H15NO7/c1-7-4-3-5-9(14(21)22)12(7)15(8(2)13(19)20)10(16)6-11(17)18/h3-5,8H,6H2,1-2H3,(H,17,18)(H,19,20)(H,21,22) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Portugal Benalaxyl-M (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance 2-{(Carboxyacetyl)[(1RS)-1-carboxyethyl]amino}-3-methylbenzoic acid 2-[(carboxyacetyl)(1-carboxyethyl)amino]-3-methylbenzoic acid Not in list C14H15NO7 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C(=O)O)C(=O)O InChI=1S/C14H15NO7/c1-7-4-3-5-9(14(21)22)12(7)15(8(2)13(19)20)10(16)6-11(17)18/h3-5,8H,6H2,1-2H3,(H,17,18)(H,19,20)(H,21,22) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Portugal Benalaxyl-M (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance Methyl N-(malonyl)-N-(2,6-xylyl)-D-alaninate 3-{(2,6-dimethylphenyl)[(2R)-1-methoxy-1-oxopropan-2-yl]amino}-3-oxopropanoic acid Not in list C15H19NO5 C[C@@H](N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC InChI=1/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)/t11-/m1/s1 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Portugal Benalaxyl-M (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance Methyl N-(malonyl)-N-(2,6-xylyl)-D-alaninate 3-{(2,6-dimethylphenyl)[(2R)-1-methoxy-1-oxopropan-2-yl]amino}-3-oxopropanoic acid Not in list C15H19NO5 C[C@@H](N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC InChI=1/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)/t11-/m1/s1 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Portugal Benalaxyl-M (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance 2-{(Carboxyacetyl)[(2RS)-1-methoxy-1-oxo-2-propanyl]amino}-3-methylbenzoic acid 2-[(carboxyacetyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-methylbenzoic acid Not in list CC(N(C(=O)CC(=O)O)c1c(C)cccc1C(=O)O)C(=O)OC InChI=1/C15H17NO7/c1-8-5-4-6-10(14(20)21)13(8)16(9(2)15(22)23-3)11(17)7-12(18)19/h4-6,9H,7H2,1-3H3,(H,18,19)(H,20,21) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data without Negative no information RMS: Portugal Benalaxyl-M (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance 2-{(Carboxyacetyl)[(2RS)-1-methoxy-1-oxo-2-propanyl]amino}-3-methylbenzoic acid 2-[(carboxyacetyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-methylbenzoic acid Not in list CC(N(C(=O)CC(=O)O)c1c(C)cccc1C(=O)O)C(=O)OC InChI=1/C15H17NO7/c1-8-5-4-6-10(14(20)21)13(8)16(9(2)15(22)23-3)11(17)7-12(18)19/h4-6,9H,7H2,1-3H3,(H,18,19)(H,20,21) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data with Negative no information RMS: Portugal Benalaxyl-M (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance 2-{(Carboxyacetyl)[(1RS)-1-carboxyethyl]amino}-3-methylbenzoic acid 2-[(carboxyacetyl)(1-carboxyethyl)amino]-3-methylbenzoic acid Not in list C14H15NO7 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C(=O)O)C(=O)O InChI=1S/C14H15NO7/c1-7-4-3-5-9(14(21)22)12(7)15(8(2)13(19)20)10(16)6-11(17)18/h3-5,8H,6H2,1-2H3,(H,17,18)(H,19,20)(H,21,22) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Portugal Benalaxyl-M (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance 2-{(Carboxyacetyl)[(1RS)-1-carboxyethyl]amino}-3-methylbenzoic acid 2-[(carboxyacetyl)(1-carboxyethyl)amino]-3-methylbenzoic acid Not in list C14H15NO7 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C(=O)O)C(=O)O InChI=1S/C14H15NO7/c1-7-4-3-5-9(14(21)22)12(7)15(8(2)13(19)20)10(16)6-11(17)18/h3-5,8H,6H2,1-2H3,(H,17,18)(H,19,20)(H,21,22) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Portugal Benalaxyl-M (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance 2-{(Carboxyacetyl)[(2RS)-1-methoxy-1-oxo-2-propanyl]amino}-3-methylbenzoic acid 2-[(carboxyacetyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-methylbenzoic acid Not in list CC(N(C(=O)CC(=O)O)c1c(C)cccc1C(=O)O)C(=O)OC InChI=1/C15H17NO7/c1-8-5-4-6-10(14(20)21)13(8)16(9(2)15(22)23-3)11(17)7-12(18)19/h4-6,9H,7H2,1-3H3,(H,18,19)(H,20,21) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI Male/Female Not reported 68.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Portugal Benalaxyl-M (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance 2-{(Carboxyacetyl)[(2RS)-1-methoxy-1-oxo-2-propanyl]amino}-3-methylbenzoic acid 2-[(carboxyacetyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-methylbenzoic acid Not in list CC(N(C(=O)CC(=O)O)c1c(C)cccc1C(=O)O)C(=O)OC InChI=1/C15H17NO7/c1-8-5-4-6-10(14(20)21)13(8)16(9(2)15(22)23-3)11(17)7-12(18)19/h4-6,9H,7H2,1-3H3,(H,18,19)(H,20,21) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI Male/Female Not reported 44.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Portugal Benalaxyl-M (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance 2-{(Carboxyacetyl)[(1RS)-1-carboxyethyl]amino}-3-methylbenzoic acid 2-[(carboxyacetyl)(1-carboxyethyl)amino]-3-methylbenzoic acid Not in list C14H15NO7 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C(=O)O)C(=O)O InChI=1S/C14H15NO7/c1-7-4-3-5-9(14(21)22)12(7)15(8(2)13(19)20)10(16)6-11(17)18/h3-5,8H,6H2,1-2H3,(H,17,18)(H,19,20)(H,21,22) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI Male/Female Not reported 68.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Portugal Benalaxyl-M (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Benalaxyl-M 98243-83-5 single chemical entity Component is a metabolite of the substance 2-{(Carboxyacetyl)[(1RS)-1-carboxyethyl]amino}-3-methylbenzoic acid 2-[(carboxyacetyl)(1-carboxyethyl)amino]-3-methylbenzoic acid Not in list C14H15NO7 CC(N(C(=O)CC(=O)O)c1c(C)cccc1C(=O)O)C(=O)O InChI=1S/C14H15NO7/c1-7-4-3-5-9(14(21)22)12(7)15(8(2)13(19)20)10(16)6-11(17)18/h3-5,8H,6H2,1-2H3,(H,17,18)(H,19,20)(H,21,22) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI Male/Female Not reported 44.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Portugal Benalaxyl-M (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M. 04Apr2013 2013 doi:10.2903/j.efsa.2013.3148
+Bupirimate 255-391-2 41483-43-6 single chemical entity Component is identical to the substance Bupirimate 255-391-2 41483-43-6 5-butyl-2-(ethylamino)-6-methylpyrimidin-4-yl dimethylsulfamate Bupirimate C13H24N4O3S O=S(OC1=C(CCCC)C(C)=NC(NCC)=N1)(N(C)C)=O InChI=1S/C13H24N4O3S/c1-6-8-9-11-10(3)15-13(14-7-2)16-12(11)20-21(18,19)17(4)5/h6-9H2,1-5H3,(H,14,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Bupirimate (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate 05Oct2010 2010 doi:10.2903/j.efsa.2010.1786
+Bupirimate 255-391-2 41483-43-6 single chemical entity Component is identical to the substance Bupirimate 255-391-2 41483-43-6 5-butyl-2-(ethylamino)-6-methylpyrimidin-4-yl dimethylsulfamate Bupirimate C13H24N4O3S O=S(OC1=C(CCCC)C(C)=NC(NCC)=N1)(N(C)C)=O InChI=1S/C13H24N4O3S/c1-6-8-9-11-10(3)15-13(14-7-2)16-12(11)20-21(18,19)17(4)5/h6-9H2,1-5H3,(H,14,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Bupirimate (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate 05Oct2010 2010 doi:10.2903/j.efsa.2010.1786
+Bupirimate 255-391-2 41483-43-6 single chemical entity Component is identical to the substance Bupirimate 255-391-2 41483-43-6 5-butyl-2-(ethylamino)-6-methylpyrimidin-4-yl dimethylsulfamate Bupirimate C13H24N4O3S O=S(OC1=C(CCCC)C(C)=NC(NCC)=N1)(N(C)C)=O InChI=1S/C13H24N4O3S/c1-6-8-9-11-10(3)15-13(14-7-2)16-12(11)20-21(18,19)17(4)5/h6-9H2,1-5H3,(H,14,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Bupirimate (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate 05Oct2010 2010 doi:10.2903/j.efsa.2010.1786
+Bupirimate 255-391-2 41483-43-6 single chemical entity Component is identical to the substance Bupirimate 255-391-2 41483-43-6 5-butyl-2-(ethylamino)-6-methylpyrimidin-4-yl dimethylsulfamate Bupirimate C13H24N4O3S O=S(OC1=C(CCCC)C(C)=NC(NCC)=N1)(N(C)C)=O InChI=1S/C13H24N4O3S/c1-6-8-9-11-10(3)15-13(14-7-2)16-12(11)20-21(18,19)17(4)5/h6-9H2,1-5H3,(H,14,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Bupirimate (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate 05Oct2010 2010 doi:10.2903/j.efsa.2010.1786
+Bupirimate 255-391-2 41483-43-6 single chemical entity Component is identical to the substance Bupirimate 255-391-2 41483-43-6 5-butyl-2-(ethylamino)-6-methylpyrimidin-4-yl dimethylsulfamate Bupirimate C13H24N4O3S O=S(OC1=C(CCCC)C(C)=NC(NCC)=N1)(N(C)C)=O InChI=1S/C13H24N4O3S/c1-6-8-9-11-10(3)15-13(14-7-2)16-12(11)20-21(18,19)17(4)5/h6-9H2,1-5H3,(H,14,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Bupirimate (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate 05Oct2010 2010 doi:10.2903/j.efsa.2010.1786
+Bupirimate 255-391-2 41483-43-6 single chemical entity Component is identical to the substance Bupirimate 255-391-2 41483-43-6 5-butyl-2-(ethylamino)-6-methylpyrimidin-4-yl dimethylsulfamate Bupirimate C13H24N4O3S O=S(OC1=C(CCCC)C(C)=NC(NCC)=N1)(N(C)C)=O InChI=1S/C13H24N4O3S/c1-6-8-9-11-10(3)15-13(14-7-2)16-12(11)20-21(18,19)17(4)5/h6-9H2,1-5H3,(H,14,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Bupirimate (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate 05Oct2010 2010 doi:10.2903/j.efsa.2010.1786
+Bupirimate 255-391-2 41483-43-6 single chemical entity Component is identical to the substance Bupirimate 255-391-2 41483-43-6 5-butyl-2-(ethylamino)-6-methylpyrimidin-4-yl dimethylsulfamate Bupirimate C13H24N4O3S O=S(OC1=C(CCCC)C(C)=NC(NCC)=N1)(N(C)C)=O InChI=1S/C13H24N4O3S/c1-6-8-9-11-10(3)15-13(14-7-2)16-12(11)20-21(18,19)17(4)5/h6-9H2,1-5H3,(H,14,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Bupirimate (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate 05Oct2010 2010 doi:10.2903/j.efsa.2010.1786
+Bupirimate 255-391-2 41483-43-6 single chemical entity Component is identical to the substance Bupirimate 255-391-2 41483-43-6 5-butyl-2-(ethylamino)-6-methylpyrimidin-4-yl dimethylsulfamate Bupirimate C13H24N4O3S O=S(OC1=C(CCCC)C(C)=NC(NCC)=N1)(N(C)C)=O InChI=1S/C13H24N4O3S/c1-6-8-9-11-10(3)15-13(14-7-2)16-12(11)20-21(18,19)17(4)5/h6-9H2,1-5H3,(H,14,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Bupirimate (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate 05Oct2010 2010 doi:10.2903/j.efsa.2010.1786
+Bupirimate 255-391-2 41483-43-6 single chemical entity Component is identical to the substance Bupirimate 255-391-2 41483-43-6 5-butyl-2-(ethylamino)-6-methylpyrimidin-4-yl dimethylsulfamate Bupirimate C13H24N4O3S O=S(OC1=C(CCCC)C(C)=NC(NCC)=N1)(N(C)C)=O InChI=1S/C13H24N4O3S/c1-6-8-9-11-10(3)15-13(14-7-2)16-12(11)20-21(18,19)17(4)5/h6-9H2,1-5H3,(H,14,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Bupirimate (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate 05Oct2010 2010 doi:10.2903/j.efsa.2010.1786
+Bupirimate 255-391-2 41483-43-6 single chemical entity Component is identical to the substance Bupirimate 255-391-2 41483-43-6 5-butyl-2-(ethylamino)-6-methylpyrimidin-4-yl dimethylsulfamate Bupirimate C13H24N4O3S O=S(OC1=C(CCCC)C(C)=NC(NCC)=N1)(N(C)C)=O InChI=1S/C13H24N4O3S/c1-6-8-9-11-10(3)15-13(14-7-2)16-12(11)20-21(18,19)17(4)5/h6-9H2,1-5H3,(H,14,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Bupirimate (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate 05Oct2010 2010 doi:10.2903/j.efsa.2010.1786
+Buprofezin 69327-76-0 single chemical entity Component is a metabolite of the substance 5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinane-2,4-dione 5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinane-2,4-dione Not in list C12H14N2O2S CC(C)N2C(=O)SCN(c1ccccc1)C2=O InChI=1/C12H14N2O2S/c1-9(2)14-11(15)13(8-17-12(14)16)10-6-4-3-5-7-10/h3-7,9H,8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Buprofezin (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is a metabolite of the substance 5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinane-2,4-dione 5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinane-2,4-dione Not in list C12H14N2O2S CC(C)N2C(=O)SCN(c1ccccc1)C2=O InChI=1/C12H14N2O2S/c1-9(2)14-11(15)13(8-17-12(14)16)10-6-4-3-5-7-10/h3-7,9H,8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Buprofezin (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is a metabolite of the substance 5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinane-2,4-dione 5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinane-2,4-dione Not in list C12H14N2O2S CC(C)N2C(=O)SCN(c1ccccc1)C2=O InChI=1/C12H14N2O2S/c1-9(2)14-11(15)13(8-17-12(14)16)10-6-4-3-5-7-10/h3-7,9H,8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Buprofezin (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is a metabolite of the substance 5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinane-2,4-dione 5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinane-2,4-dione Not in list C12H14N2O2S CC(C)N2C(=O)SCN(c1ccccc1)C2=O InChI=1/C12H14N2O2S/c1-9(2)14-11(15)13(8-17-12(14)16)10-6-4-3-5-7-10/h3-7,9H,8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Buprofezin (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is a metabolite of the substance 5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinane-2,4-dione 5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinane-2,4-dione Not in list C12H14N2O2S CC(C)N2C(=O)SCN(c1ccccc1)C2=O InChI=1/C12H14N2O2S/c1-9(2)14-11(15)13(8-17-12(14)16)10-6-4-3-5-7-10/h3-7,9H,8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Buprofezin (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is a metabolite of the substance 5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinane-2,4-dione 5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinane-2,4-dione Not in list C12H14N2O2S CC(C)N2C(=O)SCN(c1ccccc1)C2=O InChI=1/C12H14N2O2S/c1-9(2)14-11(15)13(8-17-12(14)16)10-6-4-3-5-7-10/h3-7,9H,8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Buprofezin (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is a metabolite of the substance 5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinane-2,4-dione 5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinane-2,4-dione Not in list C12H14N2O2S CC(C)N2C(=O)SCN(c1ccccc1)C2=O InChI=1/C12H14N2O2S/c1-9(2)14-11(15)13(8-17-12(14)16)10-6-4-3-5-7-10/h3-7,9H,8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Buprofezin (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is a metabolite of the substance 5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinane-2,4-dione 5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinane-2,4-dione Not in list C12H14N2O2S CC(C)N2C(=O)SCN(c1ccccc1)C2=O InChI=1/C12H14N2O2S/c1-9(2)14-11(15)13(8-17-12(14)16)10-6-4-3-5-7-10/h3-7,9H,8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Buprofezin (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is a metabolite of the substance 5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinane-2,4-dione 5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinane-2,4-dione Not in list C12H14N2O2S CC(C)N2C(=O)SCN(c1ccccc1)C2=O InChI=1/C12H14N2O2S/c1-9(2)14-11(15)13(8-17-12(14)16)10-6-4-3-5-7-10/h3-7,9H,8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Buprofezin (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is a metabolite of the substance 5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinane-2,4-dione 5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinane-2,4-dione Not in list C12H14N2O2S CC(C)N2C(=O)SCN(c1ccccc1)C2=O InChI=1/C12H14N2O2S/c1-9(2)14-11(15)13(8-17-12(14)16)10-6-4-3-5-7-10/h3-7,9H,8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Buprofezin (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is a metabolite of the substance N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide Not in list C15H23N3O2 O=C(Nc1ccccc1)N(C(=O)NC(C)(C)C)C(C)C InChI=1/C15H23N3O2/c1-11(2)18(14(20)17-15(3,4)5)13(19)16-12-9-7-6-8-10-12/h6-11H,1-5H3,(H,16,19)(H,17,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Buprofezin (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is a metabolite of the substance N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide Not in list C15H23N3O2 O=C(Nc1ccccc1)N(C(=O)NC(C)(C)C)C(C)C InChI=1/C15H23N3O2/c1-11(2)18(14(20)17-15(3,4)5)13(19)16-12-9-7-6-8-10-12/h6-11H,1-5H3,(H,16,19)(H,17,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Buprofezin (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is a metabolite of the substance N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide Not in list C15H23N3O2 O=C(Nc1ccccc1)N(C(=O)NC(C)(C)C)C(C)C InChI=1/C15H23N3O2/c1-11(2)18(14(20)17-15(3,4)5)13(19)16-12-9-7-6-8-10-12/h6-11H,1-5H3,(H,16,19)(H,17,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Buprofezin (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is a metabolite of the substance N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide Not in list C15H23N3O2 O=C(Nc1ccccc1)N(C(=O)NC(C)(C)C)C(C)C InChI=1/C15H23N3O2/c1-11(2)18(14(20)17-15(3,4)5)13(19)16-12-9-7-6-8-10-12/h6-11H,1-5H3,(H,16,19)(H,17,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Buprofezin (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is a metabolite of the substance N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide Not in list C15H23N3O2 O=C(Nc1ccccc1)N(C(=O)NC(C)(C)C)C(C)C InChI=1/C15H23N3O2/c1-11(2)18(14(20)17-15(3,4)5)13(19)16-12-9-7-6-8-10-12/h6-11H,1-5H3,(H,16,19)(H,17,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Buprofezin (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is a metabolite of the substance N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide Not in list C15H23N3O2 O=C(Nc1ccccc1)N(C(=O)NC(C)(C)C)C(C)C InChI=1/C15H23N3O2/c1-11(2)18(14(20)17-15(3,4)5)13(19)16-12-9-7-6-8-10-12/h6-11H,1-5H3,(H,16,19)(H,17,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Buprofezin (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is a metabolite of the substance N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide Not in list C15H23N3O2 O=C(Nc1ccccc1)N(C(=O)NC(C)(C)C)C(C)C InChI=1/C15H23N3O2/c1-11(2)18(14(20)17-15(3,4)5)13(19)16-12-9-7-6-8-10-12/h6-11H,1-5H3,(H,16,19)(H,17,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Buprofezin (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is a metabolite of the substance N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide Not in list C15H23N3O2 O=C(Nc1ccccc1)N(C(=O)NC(C)(C)C)C(C)C InChI=1/C15H23N3O2/c1-11(2)18(14(20)17-15(3,4)5)13(19)16-12-9-7-6-8-10-12/h6-11H,1-5H3,(H,16,19)(H,17,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Buprofezin (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is a metabolite of the substance N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide Not in list C15H23N3O2 O=C(Nc1ccccc1)N(C(=O)NC(C)(C)C)C(C)C InChI=1/C15H23N3O2/c1-11(2)18(14(20)17-15(3,4)5)13(19)16-12-9-7-6-8-10-12/h6-11H,1-5H3,(H,16,19)(H,17,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Buprofezin (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is a metabolite of the substance N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide Not in list C15H23N3O2 O=C(Nc1ccccc1)N(C(=O)NC(C)(C)C)C(C)C InChI=1/C15H23N3O2/c1-11(2)18(14(20)17-15(3,4)5)13(19)16-12-9-7-6-8-10-12/h6-11H,1-5H3,(H,16,19)(H,17,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Buprofezin (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is a metabolite of the substance 1-phenyl-3-propan-2-ylurea 19895-44-4 1-phenyl-3-propan-2-ylurea Not in list C10H14N2O CC(C)NC(=O)NC1=CC=CC=C1 InChI=1S/C10H14N2O/c1-8(2)11-10(13)12-9-6-4-3-5-7-9/h3-8H,1-2H3,(H2,11,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Buprofezin (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is a metabolite of the substance 1-phenyl-3-propan-2-ylurea 19895-44-4 1-phenyl-3-propan-2-ylurea Not in list C10H14N2O CC(C)NC(=O)NC1=CC=CC=C1 InChI=1S/C10H14N2O/c1-8(2)11-10(13)12-9-6-4-3-5-7-9/h3-8H,1-2H3,(H2,11,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Buprofezin (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is a metabolite of the substance 1-phenyl-3-propan-2-ylurea 19895-44-4 1-phenyl-3-propan-2-ylurea Not in list C10H14N2O CC(C)NC(=O)NC1=CC=CC=C1 InChI=1S/C10H14N2O/c1-8(2)11-10(13)12-9-6-4-3-5-7-9/h3-8H,1-2H3,(H2,11,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Buprofezin (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is a metabolite of the substance 1-phenyl-3-propan-2-ylurea 19895-44-4 1-phenyl-3-propan-2-ylurea Not in list C10H14N2O CC(C)NC(=O)NC1=CC=CC=C1 InChI=1S/C10H14N2O/c1-8(2)11-10(13)12-9-6-4-3-5-7-9/h3-8H,1-2H3,(H2,11,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Buprofezin (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is a metabolite of the substance 1-phenyl-3-propan-2-ylurea 19895-44-4 1-phenyl-3-propan-2-ylurea Not in list C10H14N2O CC(C)NC(=O)NC1=CC=CC=C1 InChI=1S/C10H14N2O/c1-8(2)11-10(13)12-9-6-4-3-5-7-9/h3-8H,1-2H3,(H2,11,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Buprofezin (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is a metabolite of the substance 1-phenyl-3-propan-2-ylurea 19895-44-4 1-phenyl-3-propan-2-ylurea Not in list C10H14N2O CC(C)NC(=O)NC1=CC=CC=C1 InChI=1S/C10H14N2O/c1-8(2)11-10(13)12-9-6-4-3-5-7-9/h3-8H,1-2H3,(H2,11,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Buprofezin (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is a metabolite of the substance 1-phenyl-3-propan-2-ylurea 19895-44-4 1-phenyl-3-propan-2-ylurea Not in list C10H14N2O CC(C)NC(=O)NC1=CC=CC=C1 InChI=1S/C10H14N2O/c1-8(2)11-10(13)12-9-6-4-3-5-7-9/h3-8H,1-2H3,(H2,11,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Buprofezin (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is a metabolite of the substance 1-phenyl-3-propan-2-ylurea 19895-44-4 1-phenyl-3-propan-2-ylurea Not in list C10H14N2O CC(C)NC(=O)NC1=CC=CC=C1 InChI=1S/C10H14N2O/c1-8(2)11-10(13)12-9-6-4-3-5-7-9/h3-8H,1-2H3,(H2,11,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Buprofezin (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is a metabolite of the substance 1-phenyl-3-propan-2-ylurea 19895-44-4 1-phenyl-3-propan-2-ylurea Not in list C10H14N2O CC(C)NC(=O)NC1=CC=CC=C1 InChI=1S/C10H14N2O/c1-8(2)11-10(13)12-9-6-4-3-5-7-9/h3-8H,1-2H3,(H2,11,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Buprofezin (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is a metabolite of the substance 1-phenyl-3-propan-2-ylurea 19895-44-4 1-phenyl-3-propan-2-ylurea Not in list C10H14N2O CC(C)NC(=O)NC1=CC=CC=C1 InChI=1S/C10H14N2O/c1-8(2)11-10(13)12-9-6-4-3-5-7-9/h3-8H,1-2H3,(H2,11,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Buprofezin (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is a metabolite of the substance N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide Not in list C15H23N3OS O=C(Nc1ccccc1)N(C(=S)NC(C)(C)C)C(C)C N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Buprofezin (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is a metabolite of the substance N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide Not in list C15H23N3OS O=C(Nc1ccccc1)N(C(=S)NC(C)(C)C)C(C)C N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Buprofezin (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is a metabolite of the substance N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide Not in list C15H23N3OS O=C(Nc1ccccc1)N(C(=S)NC(C)(C)C)C(C)C N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Buprofezin (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is a metabolite of the substance N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide Not in list C15H23N3OS O=C(Nc1ccccc1)N(C(=S)NC(C)(C)C)C(C)C N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Buprofezin (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is a metabolite of the substance N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide Not in list C15H23N3OS O=C(Nc1ccccc1)N(C(=S)NC(C)(C)C)C(C)C N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Buprofezin (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is a metabolite of the substance N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide Not in list C15H23N3OS O=C(Nc1ccccc1)N(C(=S)NC(C)(C)C)C(C)C N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Buprofezin (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is a metabolite of the substance N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide Not in list C15H23N3OS O=C(Nc1ccccc1)N(C(=S)NC(C)(C)C)C(C)C N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Buprofezin (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is a metabolite of the substance N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide Not in list C15H23N3OS O=C(Nc1ccccc1)N(C(=S)NC(C)(C)C)C(C)C N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Buprofezin (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is a metabolite of the substance N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide Not in list C15H23N3OS O=C(Nc1ccccc1)N(C(=S)NC(C)(C)C)C(C)C N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Buprofezin (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Buprofezin 69327-76-0 single chemical entity Component is a metabolite of the substance N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide Not in list C15H23N3OS O=C(Nc1ccccc1)N(C(=S)NC(C)(C)C)C(C)C N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Buprofezin (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin 03Jun2010 2010 doi:10.2903/j.efsa.2010.1624
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance (2E)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}acrylic acid (2E)-3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}prop-2-enoic acid Not in list C13H9ClF3N3O3 O=C(O)/C=C/c1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F InChI=1/C13H9ClF3N3O3/c1-6-18-20(13(23)19(6)12(16)17)10-4-7(2-3-11(21)22)8(14)5-9(10)15/h2-5,12H,1H3,(H,21,22)/b3-2+ organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable Rat (as animal) Sprague-Dawley 5 Male oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect-toxicokinetic investigations RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance (2RS)-2-Chloro-3-{2-chloro-5-[4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid 2-chloro-3-{2-chloro-5-[4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid Not in list C12H8Cl2F3N3O3 O=C(O)C(Cl)Cc1cc(c(F)cc1Cl)N2N=CN(C2=O)C(F)F InChI=1/C12H8Cl2F3N3O3/c13-6-3-8(15)9(2-5(6)1-7(14)10(21)22)20-12(23)19(4-18-20)11(16)17/h2-4,7,11H,1H2,(H,21,22) organic compound Other Other chromosome aberration in vitro mammalian cell micronucleus test in vitro According to OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance (2RS)-2-Chloro-3-{2-chloro-5-[4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid 2-chloro-3-{2-chloro-5-[4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid Not in list C12H8Cl2F3N3O3 O=C(O)C(Cl)Cc1cc(c(F)cc1Cl)N2N=CN(C2=O)C(F)F InChI=1/C12H8Cl2F3N3O3/c13-6-3-8(15)9(2-5(6)1-7(14)10(21)22)20-12(23)19(4-18-20)11(16)17/h2-4,7,11H,1H2,(H,21,22) organic compound Other Other chromosome aberration in vitro mammalian cell micronucleus test in vitro According to OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 4-(Difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one 4-(difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one Not in list C4H5F2N3O O=C1NN=C(C)N1C(F)F InChI=1/C4H5F2N3O/c1-2-7-8-4(10)9(2)3(5)6/h3H,1H3,(H,8,10) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable Rat (as animal) Sprague-Dawley 5 Male oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect-toxicokinetic investigations RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 3-{2-Chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid 3-{2-chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid Not in list C11H11ClF3N3O4 O=C(O)CCc1cc(c(F)cc1Cl)N2N=C(CO)N(C2=O)C(F)F InChI=1/C13H11ClF3N3O4/c14-7-4-8(15)9(3-6(7)1-2-11(22)23)20-13(24)19(12(16)17)10(5-21)18-20/h3-4,12,21H,1-2,5H2,(H,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 3-{2-Chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid 3-{2-chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid Not in list C11H11ClF3N3O4 O=C(O)CCc1cc(c(F)cc1Cl)N2N=C(CO)N(C2=O)C(F)F InChI=1/C13H11ClF3N3O4/c14-7-4-8(15)9(3-6(7)1-2-11(22)23)20-13(24)19(12(16)17)10(5-21)18-20/h3-4,12,21H,1-2,5H2,(H,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 3-{2-Chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid 3-{2-chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid Not in list C11H11ClF3N3O4 O=C(O)CCc1cc(c(F)cc1Cl)N2N=C(CO)N(C2=O)C(F)F InChI=1/C13H11ClF3N3O4/c14-7-4-8(15)9(3-6(7)1-2-11(22)23)20-13(24)19(12(16)17)10(5-21)18-20/h3-4,12,21H,1-2,5H2,(H,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 3-{2-Chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid 3-{2-chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid Not in list C11H11ClF3N3O4 O=C(O)CCc1cc(c(F)cc1Cl)N2N=C(CO)N(C2=O)C(F)F InChI=1/C13H11ClF3N3O4/c14-7-4-8(15)9(3-6(7)1-2-11(22)23)20-13(24)19(12(16)17)10(5-21)18-20/h3-4,12,21H,1-2,5H2,(H,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 3-{2-Chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid 3-{2-chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid Not in list C11H11ClF3N3O4 O=C(O)CCc1cc(c(F)cc1Cl)N2N=C(CO)N(C2=O)C(F)F InChI=1/C13H11ClF3N3O4/c14-7-4-8(15)9(3-6(7)1-2-11(22)23)20-13(24)19(12(16)17)10(5-21)18-20/h3-4,12,21H,1-2,5H2,(H,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 3-{2-Chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid 3-{2-chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid Not in list C11H11ClF3N3O4 O=C(O)CCc1cc(c(F)cc1Cl)N2N=C(CO)N(C2=O)C(F)F InChI=1/C13H11ClF3N3O4/c14-7-4-8(15)9(3-6(7)1-2-11(22)23)20-13(24)19(12(16)17)10(5-21)18-20/h3-4,12,21H,1-2,5H2,(H,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 3-{2-Chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid 3-{2-chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid Not in list C11H11ClF3N3O4 O=C(O)CCc1cc(c(F)cc1Cl)N2N=C(CO)N(C2=O)C(F)F InChI=1/C13H11ClF3N3O4/c14-7-4-8(15)9(3-6(7)1-2-11(22)23)20-13(24)19(12(16)17)10(5-21)18-20/h3-4,12,21H,1-2,5H2,(H,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 3-{2-Chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid 3-{2-chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid Not in list C11H11ClF3N3O4 O=C(O)CCc1cc(c(F)cc1Cl)N2N=C(CO)N(C2=O)C(F)F InChI=1/C13H11ClF3N3O4/c14-7-4-8(15)9(3-6(7)1-2-11(22)23)20-13(24)19(12(16)17)10(5-21)18-20/h3-4,12,21H,1-2,5H2,(H,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 3-{2-Chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid 3-{2-chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid Not in list C11H11ClF3N3O4 O=C(O)CCc1cc(c(F)cc1Cl)N2N=C(CO)N(C2=O)C(F)F InChI=1/C13H11ClF3N3O4/c14-7-4-8(15)9(3-6(7)1-2-11(22)23)20-13(24)19(12(16)17)10(5-21)18-20/h3-4,12,21H,1-2,5H2,(H,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Carfentrazone-ethyl 603-291-8 128639-02-1 single chemical entity Component is a metabolite of the substance 3-{2-Chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid 3-{2-chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid Not in list C11H11ClF3N3O4 O=C(O)CCc1cc(c(F)cc1Cl)N2N=C(CO)N(C2=O)C(F)F InChI=1/C13H11ClF3N3O4/c14-7-4-8(15)9(3-6(7)1-2-11(22)23)20-13(24)19(12(16)17)10(5-21)18-20/h3-4,12,21H,1-2,5H2,(H,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: France Carfentrazone-ethyl 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl 30Aug2016 2016 doi:10.2903/j.efsa.2016.4569
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 3-[(2RS)-2-(ethylsulfinyl)propyl]pentanedioic acid 3-[2-(ethylsulfinyl)propyl]pentanedioic acid Not in list C10H18O5S CCS(=O)C(C)CC(CC(=O)O)CC(=O)O InChI=1/C10H18O5S/c1-3-16(15)7(2)4-8(5-9(11)12)6-10(13)14/h7-8H,3-6H2,1-2H3,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Clethodim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 3-[(2RS)-2-(ethylsulfinyl)propyl]pentanedioic acid 3-[2-(ethylsulfinyl)propyl]pentanedioic acid Not in list C10H18O5S CCS(=O)C(C)CC(CC(=O)O)CC(=O)O InChI=1/C10H18O5S/c1-3-16(15)7(2)4-8(5-9(11)12)6-10(13)14/h7-8H,3-6H2,1-2H3,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Clethodim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 3-[(2RS)-2-(ethylsulfinyl)propyl]pentanedioic acid 3-[2-(ethylsulfinyl)propyl]pentanedioic acid Not in list C10H18O5S CCS(=O)C(C)CC(CC(=O)O)CC(=O)O InChI=1/C10H18O5S/c1-3-16(15)7(2)4-8(5-9(11)12)6-10(13)14/h7-8H,3-6H2,1-2H3,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Clethodim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 3-[(2RS)-2-(ethylsulfinyl)propyl]pentanedioic acid 3-[2-(ethylsulfinyl)propyl]pentanedioic acid Not in list C10H18O5S CCS(=O)C(C)CC(CC(=O)O)CC(=O)O InChI=1/C10H18O5S/c1-3-16(15)7(2)4-8(5-9(11)12)6-10(13)14/h7-8H,3-6H2,1-2H3,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Clethodim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 3-[(2RS)-2-(ethylsulfinyl)propyl]pentanedioic acid 3-[2-(ethylsulfinyl)propyl]pentanedioic acid Not in list C10H18O5S CCS(=O)C(C)CC(CC(=O)O)CC(=O)O InChI=1/C10H18O5S/c1-3-16(15)7(2)4-8(5-9(11)12)6-10(13)14/h7-8H,3-6H2,1-2H3,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Clethodim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 3-[(2RS)-2-(ethylsulfinyl)propyl]pentanedioic acid 3-[2-(ethylsulfinyl)propyl]pentanedioic acid Not in list C10H18O5S CCS(=O)C(C)CC(CC(=O)O)CC(=O)O InChI=1/C10H18O5S/c1-3-16(15)7(2)4-8(5-9(11)12)6-10(13)14/h7-8H,3-6H2,1-2H3,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Clethodim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 3-[(2RS)-2-(ethylsulfinyl)propyl]pentanedioic acid 3-[2-(ethylsulfinyl)propyl]pentanedioic acid Not in list C10H18O5S CCS(=O)C(C)CC(CC(=O)O)CC(=O)O InChI=1/C10H18O5S/c1-3-16(15)7(2)4-8(5-9(11)12)6-10(13)14/h7-8H,3-6H2,1-2H3,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Clethodim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 3-[(2RS)-2-(ethylsulfinyl)propyl]pentanedioic acid 3-[2-(ethylsulfinyl)propyl]pentanedioic acid Not in list C10H18O5S CCS(=O)C(C)CC(CC(=O)O)CC(=O)O InChI=1/C10H18O5S/c1-3-16(15)7(2)4-8(5-9(11)12)6-10(13)14/h7-8H,3-6H2,1-2H3,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Clethodim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 3-[(2RS)-2-(ethylsulfinyl)propyl]pentanedioic acid 3-[2-(ethylsulfinyl)propyl]pentanedioic acid Not in list C10H18O5S CCS(=O)C(C)CC(CC(=O)O)CC(=O)O InChI=1/C10H18O5S/c1-3-16(15)7(2)4-8(5-9(11)12)6-10(13)14/h7-8H,3-6H2,1-2H3,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Clethodim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 3-[(2RS)-2-(ethylsulfinyl)propyl]pentanedioic acid 3-[2-(ethylsulfinyl)propyl]pentanedioic acid Not in list C10H18O5S CCS(=O)C(C)CC(CC(=O)O)CC(=O)O InChI=1/C10H18O5S/c1-3-16(15)7(2)4-8(5-9(11)12)6-10(13)14/h7-8H,3-6H2,1-2H3,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Clethodim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 3-[(2RS)-2-(ethylsulfinyl)propyl]pentanedioic acid 3-[2-(ethylsulfinyl)propyl]pentanedioic acid Not in list C10H18O5S CCS(=O)C(C)CC(CC(=O)O)CC(=O)O InChI=1/C10H18O5S/c1-3-16(15)7(2)4-8(5-9(11)12)6-10(13)14/h7-8H,3-6H2,1-2H3,(H,11,12)(H,13,14) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes without Negative RMS: The Netherlands Clethodim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 3-[(2RS)-2-(ethylsulfinyl)propyl]pentanedioic acid 3-[2-(ethylsulfinyl)propyl]pentanedioic acid Not in list C10H18O5S CCS(=O)C(C)CC(CC(=O)O)CC(=O)O InChI=1/C10H18O5S/c1-3-16(15)7(2)4-8(5-9(11)12)6-10(13)14/h7-8H,3-6H2,1-2H3,(H,11,12)(H,13,14) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes with Negative RMS: The Netherlands Clethodim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 3-[(2RS)-2-(ethylsulfonyl)propyl]pentanedioic acid 3-[2-(ethylsulfonyl)propyl]pentanedioic acid Not in list C10H18O6S CCS(=O)(=O)C(C)CC(CC(=O)O)CC(=O)O InChI=1/C10H18O6S/c1-3-17(15,16)7(2)4-8(5-9(11)12)6-10(13)14/h7-8H,3-6H2,1-2H3,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Clethodim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 3-[(2RS)-2-(ethylsulfonyl)propyl]pentanedioic acid 3-[2-(ethylsulfonyl)propyl]pentanedioic acid Not in list C10H18O6S CCS(=O)(=O)C(C)CC(CC(=O)O)CC(=O)O InChI=1/C10H18O6S/c1-3-17(15,16)7(2)4-8(5-9(11)12)6-10(13)14/h7-8H,3-6H2,1-2H3,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Clethodim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 3-[(2RS)-2-(ethylsulfonyl)propyl]pentanedioic acid 3-[2-(ethylsulfonyl)propyl]pentanedioic acid Not in list C10H18O6S CCS(=O)(=O)C(C)CC(CC(=O)O)CC(=O)O InChI=1/C10H18O6S/c1-3-17(15,16)7(2)4-8(5-9(11)12)6-10(13)14/h7-8H,3-6H2,1-2H3,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Clethodim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 3-[(2RS)-2-(ethylsulfonyl)propyl]pentanedioic acid 3-[2-(ethylsulfonyl)propyl]pentanedioic acid Not in list C10H18O6S CCS(=O)(=O)C(C)CC(CC(=O)O)CC(=O)O InChI=1/C10H18O6S/c1-3-17(15,16)7(2)4-8(5-9(11)12)6-10(13)14/h7-8H,3-6H2,1-2H3,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Clethodim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 3-[(2RS)-2-(ethylsulfonyl)propyl]pentanedioic acid 3-[2-(ethylsulfonyl)propyl]pentanedioic acid Not in list C10H18O6S CCS(=O)(=O)C(C)CC(CC(=O)O)CC(=O)O InChI=1/C10H18O6S/c1-3-17(15,16)7(2)4-8(5-9(11)12)6-10(13)14/h7-8H,3-6H2,1-2H3,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Clethodim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 3-[(2RS)-2-(ethylsulfonyl)propyl]pentanedioic acid 3-[2-(ethylsulfonyl)propyl]pentanedioic acid Not in list C10H18O6S CCS(=O)(=O)C(C)CC(CC(=O)O)CC(=O)O InChI=1/C10H18O6S/c1-3-17(15,16)7(2)4-8(5-9(11)12)6-10(13)14/h7-8H,3-6H2,1-2H3,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Clethodim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 3-[(2RS)-2-(ethylsulfonyl)propyl]pentanedioic acid 3-[2-(ethylsulfonyl)propyl]pentanedioic acid Not in list C10H18O6S CCS(=O)(=O)C(C)CC(CC(=O)O)CC(=O)O InChI=1/C10H18O6S/c1-3-17(15,16)7(2)4-8(5-9(11)12)6-10(13)14/h7-8H,3-6H2,1-2H3,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Clethodim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 3-[(2RS)-2-(ethylsulfonyl)propyl]pentanedioic acid 3-[2-(ethylsulfonyl)propyl]pentanedioic acid Not in list C10H18O6S CCS(=O)(=O)C(C)CC(CC(=O)O)CC(=O)O InChI=1/C10H18O6S/c1-3-17(15,16)7(2)4-8(5-9(11)12)6-10(13)14/h7-8H,3-6H2,1-2H3,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Clethodim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 3-[(2RS)-2-(ethylsulfonyl)propyl]pentanedioic acid 3-[2-(ethylsulfonyl)propyl]pentanedioic acid Not in list C10H18O6S CCS(=O)(=O)C(C)CC(CC(=O)O)CC(=O)O InChI=1/C10H18O6S/c1-3-17(15,16)7(2)4-8(5-9(11)12)6-10(13)14/h7-8H,3-6H2,1-2H3,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Clethodim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Clethodim 99129-21-2 single chemical entity Component is a metabolite of the substance 3-[(2RS)-2-(ethylsulfonyl)propyl]pentanedioic acid 3-[2-(ethylsulfonyl)propyl]pentanedioic acid Not in list C10H18O6S CCS(=O)(=O)C(C)CC(CC(=O)O)CC(=O)O InChI=1/C10H18O6S/c1-3-17(15,16)7(2)4-8(5-9(11)12)6-10(13)14/h7-8H,3-6H2,1-2H3,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Clethodim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim 21Oct2011 2011 doi:10.2903/j.efsa.2011.2417
+Cyantraniliprole 736994-63-1 single chemical entity Component is a metabolite of the substance 3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide 3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide Not in list C9H6BrClN4O NC(=O)c2cc(Br)nn2c1ncccc1Cl InChI=1/C9H6BrClN4O/c10-7-4-6(8(12)16)15(14-7)9-5(11)2-1-3-13-9/h1-4H,(H2,12,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is a metabolite of the substance 3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide 3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide Not in list C9H6BrClN4O NC(=O)c2cc(Br)nn2c1ncccc1Cl InChI=1/C9H6BrClN4O/c10-7-4-6(8(12)16)15(14-7)9-5(11)2-1-3-13-9/h1-4H,(H2,12,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is a metabolite of the substance 3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide 3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide Not in list C9H6BrClN4O NC(=O)c2cc(Br)nn2c1ncccc1Cl InChI=1/C9H6BrClN4O/c10-7-4-6(8(12)16)15(14-7)9-5(11)2-1-3-13-9/h1-4H,(H2,12,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is a metabolite of the substance 3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide 3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide Not in list C9H6BrClN4O NC(=O)c2cc(Br)nn2c1ncccc1Cl InChI=1/C9H6BrClN4O/c10-7-4-6(8(12)16)15(14-7)9-5(11)2-1-3-13-9/h1-4H,(H2,12,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is a metabolite of the substance 3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide 3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide Not in list C9H6BrClN4O NC(=O)c2cc(Br)nn2c1ncccc1Cl InChI=1/C9H6BrClN4O/c10-7-4-6(8(12)16)15(14-7)9-5(11)2-1-3-13-9/h1-4H,(H2,12,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is a metabolite of the substance 3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide 3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide Not in list C9H6BrClN4O NC(=O)c2cc(Br)nn2c1ncccc1Cl InChI=1/C9H6BrClN4O/c10-7-4-6(8(12)16)15(14-7)9-5(11)2-1-3-13-9/h1-4H,(H2,12,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is a metabolite of the substance 3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide 3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide Not in list C9H6BrClN4O NC(=O)c2cc(Br)nn2c1ncccc1Cl InChI=1/C9H6BrClN4O/c10-7-4-6(8(12)16)15(14-7)9-5(11)2-1-3-13-9/h1-4H,(H2,12,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is a metabolite of the substance 3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide 3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide Not in list C9H6BrClN4O NC(=O)c2cc(Br)nn2c1ncccc1Cl InChI=1/C9H6BrClN4O/c10-7-4-6(8(12)16)15(14-7)9-5(11)2-1-3-13-9/h1-4H,(H2,12,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is a metabolite of the substance 3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide 3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide Not in list C9H6BrClN4O NC(=O)c2cc(Br)nn2c1ncccc1Cl InChI=1/C9H6BrClN4O/c10-7-4-6(8(12)16)15(14-7)9-5(11)2-1-3-13-9/h1-4H,(H2,12,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is a metabolite of the substance 3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide 3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide Not in list C9H6BrClN4O NC(=O)c2cc(Br)nn2c1ncccc1Cl InChI=1/C9H6BrClN4O/c10-7-4-6(8(12)16)15(14-7)9-5(11)2-1-3-13-9/h1-4H,(H2,12,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is a metabolite of the substance 3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide 3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide Not in list C9H6BrClN4O NC(=O)c2cc(Br)nn2c1ncccc1Cl InChI=1/C9H6BrClN4O/c10-7-4-6(8(12)16)15(14-7)9-5(11)2-1-3-13-9/h1-4H,(H2,12,16) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is a metabolite of the substance 3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide 3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide Not in list C9H6BrClN4O NC(=O)c2cc(Br)nn2c1ncccc1Cl InChI=1/C9H6BrClN4O/c10-7-4-6(8(12)16)15(14-7)9-5(11)2-1-3-13-9/h1-4H,(H2,12,16) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is a metabolite of the substance 3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide 3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide Not in list C9H6BrClN4O NC(=O)c2cc(Br)nn2c1ncccc1Cl InChI=1/C9H6BrClN4O/c10-7-4-6(8(12)16)15(14-7)9-5(11)2-1-3-13-9/h1-4H,(H2,12,16) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cyantraniliprole 736994-63-1 single chemical entity Component is a metabolite of the substance 3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide 3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide Not in list C9H6BrClN4O NC(=O)c2cc(Br)nn2c1ncccc1Cl InChI=1/C9H6BrClN4O/c10-7-4-6(8(12)16)15(14-7)9-5(11)2-1-3-13-9/h1-4H,(H2,12,16) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom - CoRMS: France Cyantraniliprole (Final Addendum) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole 09Sep2014 2014 doi:10.2903/j.efsa.2014.3814
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 3-(3-thianyl)glutaric acid S-dioxide 3-(1,1-dioxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid Not in list C10H16O6S O=S1(=O)CCCC(C1)C(CC(=O)O)CC(=O)O InChI=1/C10H16O6S/c11-9(12)4-8(5-10(13)14)7-2-1-3-17(15,16)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Austria Cycloxydim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 3-(3-thianyl)glutaric acid S-dioxide 3-(1,1-dioxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid Not in list C10H16O6S O=S1(=O)CCCC(C1)C(CC(=O)O)CC(=O)O InChI=1/C10H16O6S/c11-9(12)4-8(5-10(13)14)7-2-1-3-17(15,16)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Austria Cycloxydim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 3-(3-thianyl)glutaric acid S-dioxide 3-(1,1-dioxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid Not in list C10H16O6S O=S1(=O)CCCC(C1)C(CC(=O)O)CC(=O)O InChI=1/C10H16O6S/c11-9(12)4-8(5-10(13)14)7-2-1-3-17(15,16)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Austria Cycloxydim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 3-(3-thianyl)glutaric acid S-dioxide 3-(1,1-dioxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid Not in list C10H16O6S O=S1(=O)CCCC(C1)C(CC(=O)O)CC(=O)O InChI=1/C10H16O6S/c11-9(12)4-8(5-10(13)14)7-2-1-3-17(15,16)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Austria Cycloxydim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 3-(3-thianyl)glutaric acid S-dioxide 3-(1,1-dioxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid Not in list C10H16O6S O=S1(=O)CCCC(C1)C(CC(=O)O)CC(=O)O InChI=1/C10H16O6S/c11-9(12)4-8(5-10(13)14)7-2-1-3-17(15,16)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Austria Cycloxydim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 3-(3-thianyl)glutaric acid S-dioxide 3-(1,1-dioxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid Not in list C10H16O6S O=S1(=O)CCCC(C1)C(CC(=O)O)CC(=O)O InChI=1/C10H16O6S/c11-9(12)4-8(5-10(13)14)7-2-1-3-17(15,16)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Austria Cycloxydim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 3-(3-thianyl)glutaric acid S-dioxide 3-(1,1-dioxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid Not in list C10H16O6S O=S1(=O)CCCC(C1)C(CC(=O)O)CC(=O)O InChI=1/C10H16O6S/c11-9(12)4-8(5-10(13)14)7-2-1-3-17(15,16)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Austria Cycloxydim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 3-(3-thianyl)glutaric acid S-dioxide 3-(1,1-dioxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid Not in list C10H16O6S O=S1(=O)CCCC(C1)C(CC(=O)O)CC(=O)O InChI=1/C10H16O6S/c11-9(12)4-8(5-10(13)14)7-2-1-3-17(15,16)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Austria Cycloxydim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 3-(3-thianyl)glutaric acid S-dioxide 3-(1,1-dioxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid Not in list C10H16O6S O=S1(=O)CCCC(C1)C(CC(=O)O)CC(=O)O InChI=1/C10H16O6S/c11-9(12)4-8(5-10(13)14)7-2-1-3-17(15,16)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Austria Cycloxydim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 3-(3-thianyl)glutaric acid S-dioxide 3-(1,1-dioxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid Not in list C10H16O6S O=S1(=O)CCCC(C1)C(CC(=O)O)CC(=O)O InChI=1/C10H16O6S/c11-9(12)4-8(5-10(13)14)7-2-1-3-17(15,16)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Austria Cycloxydim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 3-hydroxy-3-(3-thianyl)glutaric acid S-dioxide 2-(1,1-dioxidotetrahydro-2H-thiopyran-3-yl)-2-hydroxybutanedioic acid Not in list C9H14O7S O=S1(=O)CCCC(C1)C(O)(CC(=O)O)C(=O)O InChI=1/C9H14O7S/c10-7(11)4-9(14,8(12)13)6-2-1-3-17(15,16)5-6/h6,14H,1-5H2,(H,10,11)(H,12,13) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Austria Cycloxydim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 3-hydroxy-3-(3-thianyl)glutaric acid S-dioxide 2-(1,1-dioxidotetrahydro-2H-thiopyran-3-yl)-2-hydroxybutanedioic acid Not in list C9H14O7S O=S1(=O)CCCC(C1)C(O)(CC(=O)O)C(=O)O InChI=1/C9H14O7S/c10-7(11)4-9(14,8(12)13)6-2-1-3-17(15,16)5-6/h6,14H,1-5H2,(H,10,11)(H,12,13) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Austria Cycloxydim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 3-hydroxy-3-(3-thianyl)glutaric acid S-dioxide 2-(1,1-dioxidotetrahydro-2H-thiopyran-3-yl)-2-hydroxybutanedioic acid Not in list C9H14O7S O=S1(=O)CCCC(C1)C(O)(CC(=O)O)C(=O)O InChI=1/C9H14O7S/c10-7(11)4-9(14,8(12)13)6-2-1-3-17(15,16)5-6/h6,14H,1-5H2,(H,10,11)(H,12,13) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: Austria Cycloxydim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 3-hydroxy-3-(3-thianyl)glutaric acid S-dioxide 2-(1,1-dioxidotetrahydro-2H-thiopyran-3-yl)-2-hydroxybutanedioic acid Not in list C9H14O7S O=S1(=O)CCCC(C1)C(O)(CC(=O)O)C(=O)O InChI=1/C9H14O7S/c10-7(11)4-9(14,8(12)13)6-2-1-3-17(15,16)5-6/h6,14H,1-5H2,(H,10,11)(H,12,13) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: Austria Cycloxydim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid 3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid Not in list C10H16O5S O=S1CCCC(C1)C(CC(=O)O)CC(=O)O InChI=1/C10H16O5S/c11-9(12)4-8(5-10(13)14)7-2-1-3-16(15)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Austria Cycloxydim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid 3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid Not in list C10H16O5S O=S1CCCC(C1)C(CC(=O)O)CC(=O)O InChI=1/C10H16O5S/c11-9(12)4-8(5-10(13)14)7-2-1-3-16(15)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Austria Cycloxydim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid 3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid Not in list C10H16O5S O=S1CCCC(C1)C(CC(=O)O)CC(=O)O InChI=1/C10H16O5S/c11-9(12)4-8(5-10(13)14)7-2-1-3-16(15)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Austria Cycloxydim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid 3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid Not in list C10H16O5S O=S1CCCC(C1)C(CC(=O)O)CC(=O)O InChI=1/C10H16O5S/c11-9(12)4-8(5-10(13)14)7-2-1-3-16(15)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Austria Cycloxydim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid 3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid Not in list C10H16O5S O=S1CCCC(C1)C(CC(=O)O)CC(=O)O InChI=1/C10H16O5S/c11-9(12)4-8(5-10(13)14)7-2-1-3-16(15)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Austria Cycloxydim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid 3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid Not in list C10H16O5S O=S1CCCC(C1)C(CC(=O)O)CC(=O)O InChI=1/C10H16O5S/c11-9(12)4-8(5-10(13)14)7-2-1-3-16(15)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Austria Cycloxydim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid 3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid Not in list C10H16O5S O=S1CCCC(C1)C(CC(=O)O)CC(=O)O InChI=1/C10H16O5S/c11-9(12)4-8(5-10(13)14)7-2-1-3-16(15)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Austria Cycloxydim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid 3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid Not in list C10H16O5S O=S1CCCC(C1)C(CC(=O)O)CC(=O)O InChI=1/C10H16O5S/c11-9(12)4-8(5-10(13)14)7-2-1-3-16(15)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Austria Cycloxydim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid 3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid Not in list C10H16O5S O=S1CCCC(C1)C(CC(=O)O)CC(=O)O InChI=1/C10H16O5S/c11-9(12)4-8(5-10(13)14)7-2-1-3-16(15)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Austria Cycloxydim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cycloxydim 101205-02-1 single chemical entity Component is a metabolite of the substance 3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid 3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid Not in list C10H16O5S O=S1CCCC(C1)C(CC(=O)O)CC(=O)O InChI=1/C10H16O5S/c11-9(12)4-8(5-10(13)14)7-2-1-3-16(15)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Austria Cycloxydim (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim 08Jul2010 2010 doi:10.2903/j.efsa.2010.1669
+Cyhalofop-butyl 601-817-0 122008-85-9 single chemical entity Component is a metabolite of the substance 4-{4-[(1R)-1-carboxyethoxy]phenoxy}-3-fluorobenzoic acid 4-{4-[(1R)-1-carboxyethoxy]phenoxy}-3-fluorobenzoic acid Cyhalofop-butyl (sum of cyhalofop butyl and its free acids) C16H13FO6 O=C(O)[C@@H](C)Oc1ccc(cc1)Oc2ccc(cc2F)C(=O)O InChI=1/C16H13FO6/c1-9(15(18)19)22-11-3-5-12(6-4-11)23-14-7-2-10(16(20)21)8-13(14)17/h2-9H,1H3,(H,18,19)(H,20,21)/t9-/m1/s1 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Italy - CoRMS: Austria Cyhalofop-butyl (RAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl) 30Jan2015 2015 doi: 10.2903/j.efsa.2015.3943
+Cyhalofop-butyl 601-817-0 122008-85-9 single chemical entity Component is a metabolite of the substance 4-{4-[(1R)-1-carboxyethoxy]phenoxy}-3-fluorobenzoic acid 4-{4-[(1R)-1-carboxyethoxy]phenoxy}-3-fluorobenzoic acid Cyhalofop-butyl (sum of cyhalofop butyl and its free acids) C16H13FO6 O=C(O)[C@@H](C)Oc1ccc(cc1)Oc2ccc(cc2F)C(=O)O InChI=1/C16H13FO6/c1-9(15(18)19)22-11-3-5-12(6-4-11)23-14-7-2-10(16(20)21)8-13(14)17/h2-9H,1H3,(H,18,19)(H,20,21)/t9-/m1/s1 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Italy - CoRMS: Austria Cyhalofop-butyl (RAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl) 30Jan2015 2015 doi: 10.2903/j.efsa.2015.3943
+Cyhalofop-butyl 601-817-0 122008-85-9 single chemical entity Component is a metabolite of the substance 4-{4-[(1R)-1-carboxyethoxy]phenoxy}-3-fluorobenzoic acid 4-{4-[(1R)-1-carboxyethoxy]phenoxy}-3-fluorobenzoic acid Cyhalofop-butyl (sum of cyhalofop butyl and its free acids) C16H13FO6 O=C(O)[C@@H](C)Oc1ccc(cc1)Oc2ccc(cc2F)C(=O)O InChI=1/C16H13FO6/c1-9(15(18)19)22-11-3-5-12(6-4-11)23-14-7-2-10(16(20)21)8-13(14)17/h2-9H,1H3,(H,18,19)(H,20,21)/t9-/m1/s1 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Italy - CoRMS: Austria Cyhalofop-butyl (RAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl) 30Jan2015 2015 doi: 10.2903/j.efsa.2015.3943
+Cyhalofop-butyl 601-817-0 122008-85-9 single chemical entity Component is a metabolite of the substance 4-{4-[(1R)-1-carboxyethoxy]phenoxy}-3-fluorobenzoic acid 4-{4-[(1R)-1-carboxyethoxy]phenoxy}-3-fluorobenzoic acid Cyhalofop-butyl (sum of cyhalofop butyl and its free acids) C16H13FO6 O=C(O)[C@@H](C)Oc1ccc(cc1)Oc2ccc(cc2F)C(=O)O InChI=1/C16H13FO6/c1-9(15(18)19)22-11-3-5-12(6-4-11)23-14-7-2-10(16(20)21)8-13(14)17/h2-9H,1H3,(H,18,19)(H,20,21)/t9-/m1/s1 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Italy - CoRMS: Austria Cyhalofop-butyl (RAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl) 30Jan2015 2015 doi: 10.2903/j.efsa.2015.3943
+Cyhalofop-butyl 601-817-0 122008-85-9 single chemical entity Component is a metabolite of the substance 4-{4-[(1R)-1-carboxyethoxy]phenoxy}-3-fluorobenzoic acid 4-{4-[(1R)-1-carboxyethoxy]phenoxy}-3-fluorobenzoic acid Cyhalofop-butyl (sum of cyhalofop butyl and its free acids) C16H13FO6 O=C(O)[C@@H](C)Oc1ccc(cc1)Oc2ccc(cc2F)C(=O)O InChI=1/C16H13FO6/c1-9(15(18)19)22-11-3-5-12(6-4-11)23-14-7-2-10(16(20)21)8-13(14)17/h2-9H,1H3,(H,18,19)(H,20,21)/t9-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Italy - CoRMS: Austria Cyhalofop-butyl (RAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl) 30Jan2015 2015 doi: 10.2903/j.efsa.2015.3943
+Cyhalofop-butyl 601-817-0 122008-85-9 single chemical entity Component is a metabolite of the substance 4-{4-[(1R)-1-carboxyethoxy]phenoxy}-3-fluorobenzoic acid 4-{4-[(1R)-1-carboxyethoxy]phenoxy}-3-fluorobenzoic acid Cyhalofop-butyl (sum of cyhalofop butyl and its free acids) C16H13FO6 O=C(O)[C@@H](C)Oc1ccc(cc1)Oc2ccc(cc2F)C(=O)O InChI=1/C16H13FO6/c1-9(15(18)19)22-11-3-5-12(6-4-11)23-14-7-2-10(16(20)21)8-13(14)17/h2-9H,1H3,(H,18,19)(H,20,21)/t9-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Italy - CoRMS: Austria Cyhalofop-butyl (RAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl) 30Jan2015 2015 doi: 10.2903/j.efsa.2015.3943
+Cyhalofop-butyl 601-817-0 122008-85-9 single chemical entity Component is a metabolite of the substance 4-{4-[(1R)-1-carboxyethoxy]phenoxy}-3-fluorobenzoic acid 4-{4-[(1R)-1-carboxyethoxy]phenoxy}-3-fluorobenzoic acid Cyhalofop-butyl (sum of cyhalofop butyl and its free acids) C16H13FO6 O=C(O)[C@@H](C)Oc1ccc(cc1)Oc2ccc(cc2F)C(=O)O InChI=1/C16H13FO6/c1-9(15(18)19)22-11-3-5-12(6-4-11)23-14-7-2-10(16(20)21)8-13(14)17/h2-9H,1H3,(H,18,19)(H,20,21)/t9-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Italy - CoRMS: Austria Cyhalofop-butyl (RAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl) 30Jan2015 2015 doi: 10.2903/j.efsa.2015.3943
+Cyhalofop-butyl 601-817-0 122008-85-9 single chemical entity Component is a metabolite of the substance 4-{4-[(1R)-1-carboxyethoxy]phenoxy}-3-fluorobenzoic acid 4-{4-[(1R)-1-carboxyethoxy]phenoxy}-3-fluorobenzoic acid Cyhalofop-butyl (sum of cyhalofop butyl and its free acids) C16H13FO6 O=C(O)[C@@H](C)Oc1ccc(cc1)Oc2ccc(cc2F)C(=O)O InChI=1/C16H13FO6/c1-9(15(18)19)22-11-3-5-12(6-4-11)23-14-7-2-10(16(20)21)8-13(14)17/h2-9H,1H3,(H,18,19)(H,20,21)/t9-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Italy - CoRMS: Austria Cyhalofop-butyl (RAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl) 30Jan2015 2015 doi: 10.2903/j.efsa.2015.3943
+Cyhalofop-butyl 601-817-0 122008-85-9 single chemical entity Component is a metabolite of the substance 4-{4-[(1R)-1-carboxyethoxy]phenoxy}-3-fluorobenzoic acid 4-{4-[(1R)-1-carboxyethoxy]phenoxy}-3-fluorobenzoic acid Cyhalofop-butyl (sum of cyhalofop butyl and its free acids) C16H13FO6 O=C(O)[C@@H](C)Oc1ccc(cc1)Oc2ccc(cc2F)C(=O)O InChI=1/C16H13FO6/c1-9(15(18)19)22-11-3-5-12(6-4-11)23-14-7-2-10(16(20)21)8-13(14)17/h2-9H,1H3,(H,18,19)(H,20,21)/t9-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Italy - CoRMS: Austria Cyhalofop-butyl (RAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl) 30Jan2015 2015 doi: 10.2903/j.efsa.2015.3943
+Cyhalofop-butyl 601-817-0 122008-85-9 single chemical entity Component is a metabolite of the substance 4-{4-[(1R)-1-carboxyethoxy]phenoxy}-3-fluorobenzoic acid 4-{4-[(1R)-1-carboxyethoxy]phenoxy}-3-fluorobenzoic acid Cyhalofop-butyl (sum of cyhalofop butyl and its free acids) C16H13FO6 O=C(O)[C@@H](C)Oc1ccc(cc1)Oc2ccc(cc2F)C(=O)O InChI=1/C16H13FO6/c1-9(15(18)19)22-11-3-5-12(6-4-11)23-14-7-2-10(16(20)21)8-13(14)17/h2-9H,1H3,(H,18,19)(H,20,21)/t9-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Italy - CoRMS: Austria Cyhalofop-butyl (RAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl) 30Jan2015 2015 doi: 10.2903/j.efsa.2015.3943
+Cyhalofop-butyl 601-817-0 122008-85-9 single chemical entity Component is a metabolite of the substance 4-{4-[(1R)-1-carboxyethoxy]phenoxy}-3-fluorobenzoic acid 4-{4-[(1R)-1-carboxyethoxy]phenoxy}-3-fluorobenzoic acid Cyhalofop-butyl (sum of cyhalofop butyl and its free acids) C16H13FO6 O=C(O)[C@@H](C)Oc1ccc(cc1)Oc2ccc(cc2F)C(=O)O InChI=1/C16H13FO6/c1-9(15(18)19)22-11-3-5-12(6-4-11)23-14-7-2-10(16(20)21)8-13(14)17/h2-9H,1H3,(H,18,19)(H,20,21)/t9-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Italy - CoRMS: Austria Cyhalofop-butyl (RAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl) 30Jan2015 2015 doi: 10.2903/j.efsa.2015.3943
+Cyhalofop-butyl 601-817-0 122008-85-9 single chemical entity Component is a metabolite of the substance 4-{4-[(1R)-1-carboxyethoxy]phenoxy}-3-fluorobenzoic acid 4-{4-[(1R)-1-carboxyethoxy]phenoxy}-3-fluorobenzoic acid Cyhalofop-butyl (sum of cyhalofop butyl and its free acids) C16H13FO6 O=C(O)[C@@H](C)Oc1ccc(cc1)Oc2ccc(cc2F)C(=O)O InChI=1/C16H13FO6/c1-9(15(18)19)22-11-3-5-12(6-4-11)23-14-7-2-10(16(20)21)8-13(14)17/h2-9H,1H3,(H,18,19)(H,20,21)/t9-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Italy - CoRMS: Austria Cyhalofop-butyl (RAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl) 30Jan2015 2015 doi: 10.2903/j.efsa.2015.3943
+Cyhalofop-butyl 601-817-0 122008-85-9 single chemical entity Component is a metabolite of the substance 4-{4-[(1R)-1-carboxyethoxy]phenoxy}-3-fluorobenzoic acid 4-{4-[(1R)-1-carboxyethoxy]phenoxy}-3-fluorobenzoic acid Cyhalofop-butyl (sum of cyhalofop butyl and its free acids) C16H13FO6 O=C(O)[C@@H](C)Oc1ccc(cc1)Oc2ccc(cc2F)C(=O)O InChI=1/C16H13FO6/c1-9(15(18)19)22-11-3-5-12(6-4-11)23-14-7-2-10(16(20)21)8-13(14)17/h2-9H,1H3,(H,18,19)(H,20,21)/t9-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Italy - CoRMS: Austria Cyhalofop-butyl (RAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl) 30Jan2015 2015 doi: 10.2903/j.efsa.2015.3943
+Cyhalofop-butyl 601-817-0 122008-85-9 single chemical entity Component is a metabolite of the substance 4-{4-[(1R)-1-carboxyethoxy]phenoxy}-3-fluorobenzoic acid 4-{4-[(1R)-1-carboxyethoxy]phenoxy}-3-fluorobenzoic acid Cyhalofop-butyl (sum of cyhalofop butyl and its free acids) C16H13FO6 O=C(O)[C@@H](C)Oc1ccc(cc1)Oc2ccc(cc2F)C(=O)O InChI=1/C16H13FO6/c1-9(15(18)19)22-11-3-5-12(6-4-11)23-14-7-2-10(16(20)21)8-13(14)17/h2-9H,1H3,(H,18,19)(H,20,21)/t9-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Italy - CoRMS: Austria Cyhalofop-butyl (RAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl) 30Jan2015 2015 doi: 10.2903/j.efsa.2015.3943
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Dazomet 208-576-7 533-74-4 single chemical entity Component is identical to the substance Dazomet 208-576-7 533-74-4 3,5-dimethyl-1,3,5-thiadiazinane-2-thione Dazomet C5H10N2S2 CN1CSC(=S)N(C)C1 InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium Dazomet (Revised) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet 07Oct2010 2010 doi:10.2903/j.efsa.2010.1833
+Geraniol 269-750-6 106-24-1 single chemical entity Component is identical to the substance Geraniol 269-750-6 106-24-1 (2E)-3,7-dimethylocta-2,6-dien-1-ol geraniol C10H18O CC(=CCCC(=CCO)C)C InChI=1S/C10H18O/c1-9(2)5-4-6-10(3)7-8-11/h5,7,11H,4,6,8H2,1-3H3/b10-7+ organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: The United Kingdom Geraniol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance geraniol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2915
+Geraniol 269-750-6 106-24-1 single chemical entity Component is identical to the substance Geraniol 269-750-6 106-24-1 (2E)-3,7-dimethylocta-2,6-dien-1-ol geraniol C10H18O CC(=CCCC(=CCO)C)C InChI=1S/C10H18O/c1-9(2)5-4-6-10(3)7-8-11/h5,7,11H,4,6,8H2,1-3H3/b10-7+ organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: The United Kingdom Geraniol (Final Addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance geraniol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2915
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is identical to the substance Ethofumesate 247-525-3 26225-79-6 (2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate Ethofumesate C13H18O5S CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian cell micronucleus test in vitro According to OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Ethofumesate 247-525-3 26225-79-6 single chemical entity Component is identical to the substance Ethofumesate 247-525-3 26225-79-6 (2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate Ethofumesate C13H18O5S CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian cell micronucleus test in vitro According to OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: Austria - CoRMS: Denmark Ethofumesate 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance ethofumesate 19Jan2016 2016 doi:10.2903/j.efsa.2016.4374
+Imazalil 252-615-0 35554-44-0 single chemical entity Component is identical to the substance Imazalil 252-615-0 35554-44-0 1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole Imazalil C14H14Cl2N2O C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands - CoRMS: Spain Imazalil 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil 19Mar2010 2010 doi:10.2903/j.efsa.2010.1526
+Imazalil 252-615-0 35554-44-0 single chemical entity Component is identical to the substance Imazalil 252-615-0 35554-44-0 1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole Imazalil C14H14Cl2N2O C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands - CoRMS: Spain Imazalil 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil 19Mar2010 2010 doi:10.2903/j.efsa.2010.1526
+Imazalil 252-615-0 35554-44-0 single chemical entity Component is identical to the substance Imazalil 252-615-0 35554-44-0 1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole Imazalil C14H14Cl2N2O C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands - CoRMS: Spain Imazalil 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil 19Mar2010 2010 doi:10.2903/j.efsa.2010.1526
+Imazalil 252-615-0 35554-44-0 single chemical entity Component is identical to the substance Imazalil 252-615-0 35554-44-0 1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole Imazalil C14H14Cl2N2O C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands - CoRMS: Spain Imazalil 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil 19Mar2010 2010 doi:10.2903/j.efsa.2010.1526
+Imazalil 252-615-0 35554-44-0 single chemical entity Component is identical to the substance Imazalil 252-615-0 35554-44-0 1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole Imazalil C14H14Cl2N2O C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands - CoRMS: Spain Imazalil 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil 19Mar2010 2010 doi:10.2903/j.efsa.2010.1526
+Imazalil 252-615-0 35554-44-0 single chemical entity Component is identical to the substance Imazalil 252-615-0 35554-44-0 1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole Imazalil C14H14Cl2N2O C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands - CoRMS: Spain Imazalil 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil 19Mar2010 2010 doi:10.2903/j.efsa.2010.1526
+Imazalil 252-615-0 35554-44-0 single chemical entity Component is identical to the substance Imazalil 252-615-0 35554-44-0 1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole Imazalil C14H14Cl2N2O C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands - CoRMS: Spain Imazalil 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil 19Mar2010 2010 doi:10.2903/j.efsa.2010.1526
+Imazalil 252-615-0 35554-44-0 single chemical entity Component is identical to the substance Imazalil 252-615-0 35554-44-0 1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole Imazalil C14H14Cl2N2O C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands - CoRMS: Spain Imazalil 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil 19Mar2010 2010 doi:10.2903/j.efsa.2010.1526
+Imazalil 252-615-0 35554-44-0 single chemical entity Component is identical to the substance Imazalil 252-615-0 35554-44-0 1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole Imazalil C14H14Cl2N2O C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands - CoRMS: Spain Imazalil 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil 19Mar2010 2010 doi:10.2903/j.efsa.2010.1526
+Imazalil 252-615-0 35554-44-0 single chemical entity Component is identical to the substance Imazalil 252-615-0 35554-44-0 1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole Imazalil C14H14Cl2N2O C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands - CoRMS: Spain Imazalil 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil 19Mar2010 2010 doi:10.2903/j.efsa.2010.1526
+Imazalil 252-615-0 35554-44-0 single chemical entity Component is identical to the substance Imazalil 252-615-0 35554-44-0 1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole Imazalil C14H14Cl2N2O C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: The Netherlands - CoRMS: Spain Imazalil 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil 19Mar2010 2010 doi:10.2903/j.efsa.2010.1526
+Imazalil 252-615-0 35554-44-0 single chemical entity Component is identical to the substance Imazalil 252-615-0 35554-44-0 1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole Imazalil C14H14Cl2N2O C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: The Netherlands - CoRMS: Spain Imazalil 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil 19Mar2010 2010 doi:10.2903/j.efsa.2010.1526
+Imazalil 252-615-0 35554-44-0 single chemical entity Component is identical to the substance Imazalil 252-615-0 35554-44-0 1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole Imazalil C14H14Cl2N2O C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: The Netherlands - CoRMS: Spain Imazalil 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil 19Mar2010 2010 doi:10.2903/j.efsa.2010.1526
+Imazalil 252-615-0 35554-44-0 single chemical entity Component is identical to the substance Imazalil 252-615-0 35554-44-0 1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole Imazalil C14H14Cl2N2O C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: The Netherlands - CoRMS: Spain Imazalil 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil 19Mar2010 2010 doi:10.2903/j.efsa.2010.1526
+Imazalil 252-615-0 35554-44-0 single chemical entity Component is identical to the substance Imazalil 252-615-0 35554-44-0 1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole Imazalil C14H14Cl2N2O C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Swiss 10 Male/Female oral: unspecified 72.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The Netherlands - CoRMS: Spain Imazalil 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil 19Mar2010 2010 doi:10.2903/j.efsa.2010.1526
+Imazalil 252-615-0 35554-44-0 single chemical entity Component is identical to the substance Imazalil 252-615-0 35554-44-0 1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole Imazalil C14H14Cl2N2O C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Swiss 10 Male/Female oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The Netherlands - CoRMS: Spain Imazalil 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil 19Mar2010 2010 doi:10.2903/j.efsa.2010.1526
+Imazalil 252-615-0 35554-44-0 single chemical entity Component is identical to the substance Imazalil 252-615-0 35554-44-0 1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole Imazalil C14H14Cl2N2O C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Swiss 10 Male/Female oral: unspecified 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The Netherlands - CoRMS: Spain Imazalil 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil 19Mar2010 2010 doi:10.2903/j.efsa.2010.1526
+Imazalil 252-615-0 35554-44-0 single chemical entity Component is identical to the substance Imazalil 252-615-0 35554-44-0 1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole Imazalil C14H14Cl2N2O C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration dominant lethal assay in vivo According to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) No Acceptable House mouse (as animal) Swiss 24 Male oral: unspecified yes not applicable Negative RMS: The Netherlands - CoRMS: Spain Imazalil 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil 19Mar2010 2010 doi:10.2903/j.efsa.2010.1526
+Imazalil 252-615-0 35554-44-0 single chemical entity Component is identical to the substance Imazalil 252-615-0 35554-44-0 1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole Imazalil C14H14Cl2N2O C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands - CoRMS: Spain Imazalil 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil 19Mar2010 2010 doi:10.2903/j.efsa.2010.1526
+Imazalil 252-615-0 35554-44-0 single chemical entity Component is identical to the substance Imazalil 252-615-0 35554-44-0 1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole Imazalil C14H14Cl2N2O C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands - CoRMS: Spain Imazalil 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil 19Mar2010 2010 doi:10.2903/j.efsa.2010.1526
+Imazalil 252-615-0 35554-44-0 single chemical entity Component is identical to the substance Imazalil 252-615-0 35554-44-0 1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole Imazalil C14H14Cl2N2O C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands - CoRMS: Spain Imazalil 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil 19Mar2010 2010 doi:10.2903/j.efsa.2010.1526
+Imazalil 252-615-0 35554-44-0 single chemical entity Component is identical to the substance Imazalil 252-615-0 35554-44-0 1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole Imazalil C14H14Cl2N2O C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands - CoRMS: Spain Imazalil 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil 19Mar2010 2010 doi:10.2903/j.efsa.2010.1526
+Imazalil 252-615-0 35554-44-0 single chemical entity Component is identical to the substance Imazalil 252-615-0 35554-44-0 1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole Imazalil C14H14Cl2N2O C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands - CoRMS: Spain Imazalil 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil 19Mar2010 2010 doi:10.2903/j.efsa.2010.1526
+Imazalil 252-615-0 35554-44-0 single chemical entity Component is identical to the substance Imazalil 252-615-0 35554-44-0 1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole Imazalil C14H14Cl2N2O C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands - CoRMS: Spain Imazalil 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil 19Mar2010 2010 doi:10.2903/j.efsa.2010.1526
+Imazalil 252-615-0 35554-44-0 single chemical entity Component is identical to the substance Imazalil 252-615-0 35554-44-0 1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole Imazalil C14H14Cl2N2O C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands - CoRMS: Spain Imazalil 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil 19Mar2010 2010 doi:10.2903/j.efsa.2010.1526
+Imazalil 252-615-0 35554-44-0 single chemical entity Component is identical to the substance Imazalil 252-615-0 35554-44-0 1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole Imazalil C14H14Cl2N2O C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands - CoRMS: Spain Imazalil 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil 19Mar2010 2010 doi:10.2903/j.efsa.2010.1526
+Imazalil 252-615-0 35554-44-0 single chemical entity Component is identical to the substance Imazalil 252-615-0 35554-44-0 1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole Imazalil C14H14Cl2N2O C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands - CoRMS: Spain Imazalil 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil 19Mar2010 2010 doi:10.2903/j.efsa.2010.1526
+Imazalil 252-615-0 35554-44-0 single chemical entity Component is identical to the substance Imazalil 252-615-0 35554-44-0 1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole Imazalil C14H14Cl2N2O C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands - CoRMS: Spain Imazalil 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil 19Mar2010 2010 doi:10.2903/j.efsa.2010.1526
+Imazalil 252-615-0 35554-44-0 single chemical entity Component is identical to the substance Imazalil 252-615-0 35554-44-0 1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole Imazalil C14H14Cl2N2O C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration dominant lethal assay in vivo According to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) No Acceptable House mouse (as animal) Swiss Female oral: unspecified yes not applicable Negative RMS: The Netherlands - CoRMS: Spain Imazalil 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil 19Mar2010 2010 doi:10.2903/j.efsa.2010.1526
+Imazaquin 81335-37-7 single chemical entity Component is identical to the substance Imazaquin 81335-37-7 2-(4-Methyl-5-oxo-4-propan-2-yl-1H-imidazol-2-yl)quinoline-3-carboxylic acid Imazaquin C17H17N3O3 CC(C)C1(C(=O)NC(=N1)C2=NC3=CC=CC=C3C=C2C(=O)O)C InChI=1S/C17H17N3O3/c1-9(2)17(3)16(23)19-14(20-17)13-11(15(21)22)8-10-6-4-5-7-12(10)18-13/h4-9H,1-3H3,(H,21,22)(H,19,20,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium Imazaquin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance imazaquin 07Jan2011 2011 doi:10.2903/j.efsa.2011.1968
+Imazaquin 81335-37-7 single chemical entity Component is identical to the substance Imazaquin 81335-37-7 2-(4-Methyl-5-oxo-4-propan-2-yl-1H-imidazol-2-yl)quinoline-3-carboxylic acid Imazaquin C17H17N3O3 CC(C)C1(C(=O)NC(=N1)C2=NC3=CC=CC=C3C=C2C(=O)O)C InChI=1S/C17H17N3O3/c1-9(2)17(3)16(23)19-14(20-17)13-11(15(21)22)8-10-6-4-5-7-12(10)18-13/h4-9H,1-3H3,(H,21,22)(H,19,20,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium Imazaquin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance imazaquin 07Jan2011 2011 doi:10.2903/j.efsa.2011.1968
+Imazaquin 81335-37-7 single chemical entity Component is identical to the substance Imazaquin 81335-37-7 2-(4-Methyl-5-oxo-4-propan-2-yl-1H-imidazol-2-yl)quinoline-3-carboxylic acid Imazaquin C17H17N3O3 CC(C)C1(C(=O)NC(=N1)C2=NC3=CC=CC=C3C=C2C(=O)O)C InChI=1S/C17H17N3O3/c1-9(2)17(3)16(23)19-14(20-17)13-11(15(21)22)8-10-6-4-5-7-12(10)18-13/h4-9H,1-3H3,(H,21,22)(H,19,20,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium Imazaquin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance imazaquin 07Jan2011 2011 doi:10.2903/j.efsa.2011.1968
+Imazaquin 81335-37-7 single chemical entity Component is identical to the substance Imazaquin 81335-37-7 2-(4-Methyl-5-oxo-4-propan-2-yl-1H-imidazol-2-yl)quinoline-3-carboxylic acid Imazaquin C17H17N3O3 CC(C)C1(C(=O)NC(=N1)C2=NC3=CC=CC=C3C=C2C(=O)O)C InChI=1S/C17H17N3O3/c1-9(2)17(3)16(23)19-14(20-17)13-11(15(21)22)8-10-6-4-5-7-12(10)18-13/h4-9H,1-3H3,(H,21,22)(H,19,20,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium Imazaquin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance imazaquin 07Jan2011 2011 doi:10.2903/j.efsa.2011.1968
+Imazaquin 81335-37-7 single chemical entity Component is identical to the substance Imazaquin 81335-37-7 2-(4-Methyl-5-oxo-4-propan-2-yl-1H-imidazol-2-yl)quinoline-3-carboxylic acid Imazaquin C17H17N3O3 CC(C)C1(C(=O)NC(=N1)C2=NC3=CC=CC=C3C=C2C(=O)O)C InChI=1S/C17H17N3O3/c1-9(2)17(3)16(23)19-14(20-17)13-11(15(21)22)8-10-6-4-5-7-12(10)18-13/h4-9H,1-3H3,(H,21,22)(H,19,20,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium Imazaquin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance imazaquin 07Jan2011 2011 doi:10.2903/j.efsa.2011.1968
+Imazaquin 81335-37-7 single chemical entity Component is identical to the substance Imazaquin 81335-37-7 2-(4-Methyl-5-oxo-4-propan-2-yl-1H-imidazol-2-yl)quinoline-3-carboxylic acid Imazaquin C17H17N3O3 CC(C)C1(C(=O)NC(=N1)C2=NC3=CC=CC=C3C=C2C(=O)O)C InChI=1S/C17H17N3O3/c1-9(2)17(3)16(23)19-14(20-17)13-11(15(21)22)8-10-6-4-5-7-12(10)18-13/h4-9H,1-3H3,(H,21,22)(H,19,20,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium Imazaquin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance imazaquin 07Jan2011 2011 doi:10.2903/j.efsa.2011.1968
+Imazaquin 81335-37-7 single chemical entity Component is identical to the substance Imazaquin 81335-37-7 2-(4-Methyl-5-oxo-4-propan-2-yl-1H-imidazol-2-yl)quinoline-3-carboxylic acid Imazaquin C17H17N3O3 CC(C)C1(C(=O)NC(=N1)C2=NC3=CC=CC=C3C=C2C(=O)O)C InChI=1S/C17H17N3O3/c1-9(2)17(3)16(23)19-14(20-17)13-11(15(21)22)8-10-6-4-5-7-12(10)18-13/h4-9H,1-3H3,(H,21,22)(H,19,20,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium Imazaquin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance imazaquin 07Jan2011 2011 doi:10.2903/j.efsa.2011.1968
+Imazaquin 81335-37-7 single chemical entity Component is identical to the substance Imazaquin 81335-37-7 2-(4-Methyl-5-oxo-4-propan-2-yl-1H-imidazol-2-yl)quinoline-3-carboxylic acid Imazaquin C17H17N3O3 CC(C)C1(C(=O)NC(=N1)C2=NC3=CC=CC=C3C=C2C(=O)O)C InChI=1S/C17H17N3O3/c1-9(2)17(3)16(23)19-14(20-17)13-11(15(21)22)8-10-6-4-5-7-12(10)18-13/h4-9H,1-3H3,(H,21,22)(H,19,20,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Belgium Imazaquin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance imazaquin 07Jan2011 2011 doi:10.2903/j.efsa.2011.1968
+Imazaquin 81335-37-7 single chemical entity Component is identical to the substance Imazaquin 81335-37-7 2-(4-Methyl-5-oxo-4-propan-2-yl-1H-imidazol-2-yl)quinoline-3-carboxylic acid Imazaquin C17H17N3O3 CC(C)C1(C(=O)NC(=N1)C2=NC3=CC=CC=C3C=C2C(=O)O)C InChI=1S/C17H17N3O3/c1-9(2)17(3)16(23)19-14(20-17)13-11(15(21)22)8-10-6-4-5-7-12(10)18-13/h4-9H,1-3H3,(H,21,22)(H,19,20,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Belgium Imazaquin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance imazaquin 07Jan2011 2011 doi:10.2903/j.efsa.2011.1968
+Imazaquin 81335-37-7 single chemical entity Component is identical to the substance Imazaquin 81335-37-7 2-(4-Methyl-5-oxo-4-propan-2-yl-1H-imidazol-2-yl)quinoline-3-carboxylic acid Imazaquin C17H17N3O3 CC(C)C1(C(=O)NC(=N1)C2=NC3=CC=CC=C3C=C2C(=O)O)C InChI=1S/C17H17N3O3/c1-9(2)17(3)16(23)19-14(20-17)13-11(15(21)22)8-10-6-4-5-7-12(10)18-13/h4-9H,1-3H3,(H,21,22)(H,19,20,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Belgium Imazaquin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance imazaquin 07Jan2011 2011 doi:10.2903/j.efsa.2011.1968
+Imazaquin 81335-37-7 single chemical entity Component is identical to the substance Imazaquin 81335-37-7 2-(4-Methyl-5-oxo-4-propan-2-yl-1H-imidazol-2-yl)quinoline-3-carboxylic acid Imazaquin C17H17N3O3 CC(C)C1(C(=O)NC(=N1)C2=NC3=CC=CC=C3C=C2C(=O)O)C InChI=1S/C17H17N3O3/c1-9(2)17(3)16(23)19-14(20-17)13-11(15(21)22)8-10-6-4-5-7-12(10)18-13/h4-9H,1-3H3,(H,21,22)(H,19,20,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Belgium Imazaquin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance imazaquin 07Jan2011 2011 doi:10.2903/j.efsa.2011.1968
+Imazaquin 81335-37-7 single chemical entity Component is identical to the substance Imazaquin 81335-37-7 2-(4-Methyl-5-oxo-4-propan-2-yl-1H-imidazol-2-yl)quinoline-3-carboxylic acid Imazaquin C17H17N3O3 CC(C)C1(C(=O)NC(=N1)C2=NC3=CC=CC=C3C=C2C(=O)O)C InChI=1S/C17H17N3O3/c1-9(2)17(3)16(23)19-14(20-17)13-11(15(21)22)8-10-6-4-5-7-12(10)18-13/h4-9H,1-3H3,(H,21,22)(H,19,20,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium Imazaquin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance imazaquin 07Jan2011 2011 doi:10.2903/j.efsa.2011.1968
+Imazaquin 81335-37-7 single chemical entity Component is identical to the substance Imazaquin 81335-37-7 2-(4-Methyl-5-oxo-4-propan-2-yl-1H-imidazol-2-yl)quinoline-3-carboxylic acid Imazaquin C17H17N3O3 CC(C)C1(C(=O)NC(=N1)C2=NC3=CC=CC=C3C=C2C(=O)O)C InChI=1S/C17H17N3O3/c1-9(2)17(3)16(23)19-14(20-17)13-11(15(21)22)8-10-6-4-5-7-12(10)18-13/h4-9H,1-3H3,(H,21,22)(H,19,20,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Belgium Imazaquin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance imazaquin 07Jan2011 2011 doi:10.2903/j.efsa.2011.1968
+Imazaquin 81335-37-7 single chemical entity Component is identical to the substance Imazaquin 81335-37-7 2-(4-Methyl-5-oxo-4-propan-2-yl-1H-imidazol-2-yl)quinoline-3-carboxylic acid Imazaquin C17H17N3O3 CC(C)C1(C(=O)NC(=N1)C2=NC3=CC=CC=C3C=C2C(=O)O)C InChI=1S/C17H17N3O3/c1-9(2)17(3)16(23)19-14(20-17)13-11(15(21)22)8-10-6-4-5-7-12(10)18-13/h4-9H,1-3H3,(H,21,22)(H,19,20,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Belgium Imazaquin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance imazaquin 07Jan2011 2011 doi:10.2903/j.efsa.2011.1968
+Imazaquin 81335-37-7 single chemical entity Component is identical to the substance Imazaquin 81335-37-7 2-(4-Methyl-5-oxo-4-propan-2-yl-1H-imidazol-2-yl)quinoline-3-carboxylic acid Imazaquin C17H17N3O3 CC(C)C1(C(=O)NC(=N1)C2=NC3=CC=CC=C3C=C2C(=O)O)C InChI=1S/C17H17N3O3/c1-9(2)17(3)16(23)19-14(20-17)13-11(15(21)22)8-10-6-4-5-7-12(10)18-13/h4-9H,1-3H3,(H,21,22)(H,19,20,23) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: Belgium Imazaquin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance imazaquin 07Jan2011 2011 doi:10.2903/j.efsa.2011.1968
+Imazaquin 81335-37-7 single chemical entity Component is identical to the substance Imazaquin 81335-37-7 2-(4-Methyl-5-oxo-4-propan-2-yl-1H-imidazol-2-yl)quinoline-3-carboxylic acid Imazaquin C17H17N3O3 CC(C)C1(C(=O)NC(=N1)C2=NC3=CC=CC=C3C=C2C(=O)O)C InChI=1S/C17H17N3O3/c1-9(2)17(3)16(23)19-14(20-17)13-11(15(21)22)8-10-6-4-5-7-12(10)18-13/h4-9H,1-3H3,(H,21,22)(H,19,20,23) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: Belgium Imazaquin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance imazaquin 07Jan2011 2011 doi:10.2903/j.efsa.2011.1968
+Imazaquin 81335-37-7 single chemical entity Component is identical to the substance Imazaquin 81335-37-7 2-(4-Methyl-5-oxo-4-propan-2-yl-1H-imidazol-2-yl)quinoline-3-carboxylic acid Imazaquin C17H17N3O3 CC(C)C1(C(=O)NC(=N1)C2=NC3=CC=CC=C3C=C2C(=O)O)C InChI=1S/C17H17N3O3/c1-9(2)17(3)16(23)19-14(20-17)13-11(15(21)22)8-10-6-4-5-7-12(10)18-13/h4-9H,1-3H3,(H,21,22)(H,19,20,23) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Belgium Imazaquin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance imazaquin 07Jan2011 2011 doi:10.2903/j.efsa.2011.1968
+Imazaquin 81335-37-7 single chemical entity Component is identical to the substance Imazaquin 81335-37-7 2-(4-Methyl-5-oxo-4-propan-2-yl-1H-imidazol-2-yl)quinoline-3-carboxylic acid Imazaquin C17H17N3O3 CC(C)C1(C(=O)NC(=N1)C2=NC3=CC=CC=C3C=C2C(=O)O)C InChI=1S/C17H17N3O3/c1-9(2)17(3)16(23)19-14(20-17)13-11(15(21)22)8-10-6-4-5-7-12(10)18-13/h4-9H,1-3H3,(H,21,22)(H,19,20,23) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Swiss 16 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Belgium Imazaquin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance imazaquin 07Jan2011 2011 doi:10.2903/j.efsa.2011.1968
+Imazaquin 81335-37-7 single chemical entity Component is identical to the substance Imazaquin 81335-37-7 2-(4-Methyl-5-oxo-4-propan-2-yl-1H-imidazol-2-yl)quinoline-3-carboxylic acid Imazaquin C17H17N3O3 CC(C)C1(C(=O)NC(=N1)C2=NC3=CC=CC=C3C=C2C(=O)O)C InChI=1S/C17H17N3O3/c1-9(2)17(3)16(23)19-14(20-17)13-11(15(21)22)8-10-6-4-5-7-12(10)18-13/h4-9H,1-3H3,(H,21,22)(H,19,20,23) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Swiss 16 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Belgium Imazaquin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance imazaquin 07Jan2011 2011 doi:10.2903/j.efsa.2011.1968
+Imazaquin 81335-37-7 single chemical entity Component is identical to the substance Imazaquin 81335-37-7 2-(4-Methyl-5-oxo-4-propan-2-yl-1H-imidazol-2-yl)quinoline-3-carboxylic acid Imazaquin C17H17N3O3 CC(C)C1(C(=O)NC(=N1)C2=NC3=CC=CC=C3C=C2C(=O)O)C InChI=1S/C17H17N3O3/c1-9(2)17(3)16(23)19-14(20-17)13-11(15(21)22)8-10-6-4-5-7-12(10)18-13/h4-9H,1-3H3,(H,21,22)(H,19,20,23) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Swiss 10 Male/Female intraperitoneal 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Belgium Imazaquin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance imazaquin 07Jan2011 2011 doi:10.2903/j.efsa.2011.1968
+Imazaquin 81335-37-7 single chemical entity Component is identical to the substance Imazaquin 81335-37-7 2-(4-Methyl-5-oxo-4-propan-2-yl-1H-imidazol-2-yl)quinoline-3-carboxylic acid Imazaquin C17H17N3O3 CC(C)C1(C(=O)NC(=N1)C2=NC3=CC=CC=C3C=C2C(=O)O)C InChI=1S/C17H17N3O3/c1-9(2)17(3)16(23)19-14(20-17)13-11(15(21)22)8-10-6-4-5-7-12(10)18-13/h4-9H,1-3H3,(H,21,22)(H,19,20,23) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent no treatment without Negative RMS: Belgium Imazaquin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance imazaquin 07Jan2011 2011 doi:10.2903/j.efsa.2011.1968
+Imazaquin 81335-37-7 single chemical entity Component is identical to the substance Imazaquin 81335-37-7 2-(4-Methyl-5-oxo-4-propan-2-yl-1H-imidazol-2-yl)quinoline-3-carboxylic acid Imazaquin C17H17N3O3 CC(C)C1(C(=O)NC(=N1)C2=NC3=CC=CC=C3C=C2C(=O)O)C InChI=1S/C17H17N3O3/c1-9(2)17(3)16(23)19-14(20-17)13-11(15(21)22)8-10-6-4-5-7-12(10)18-13/h4-9H,1-3H3,(H,21,22)(H,19,20,23) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) Yes Acceptable Rat (as animal) Crj:CD(SD) 10 Male oral: gavage 5.0000000000 D yes, concurrent vehicle not applicable Negative RMS: Belgium Imazaquin 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance imazaquin 07Jan2011 2011 doi:10.2903/j.efsa.2011.1968
+Imidacloprid 138261-41-3 single chemical entity Component is identical to the substance Imidacloprid 138261-41-3 (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine Imidacloprid C9H10ClN5O2 ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is identical to the substance Imidacloprid 138261-41-3 (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine Imidacloprid C9H10ClN5O2 ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is identical to the substance Imidacloprid 138261-41-3 (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine Imidacloprid C9H10ClN5O2 ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is identical to the substance Imidacloprid 138261-41-3 (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine Imidacloprid C9H10ClN5O2 ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is identical to the substance Imidacloprid 138261-41-3 (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine Imidacloprid C9H10ClN5O2 ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is identical to the substance Imidacloprid 138261-41-3 (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine Imidacloprid C9H10ClN5O2 ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is identical to the substance Imidacloprid 138261-41-3 (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine Imidacloprid C9H10ClN5O2 ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is identical to the substance Imidacloprid 138261-41-3 (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine Imidacloprid C9H10ClN5O2 ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Positive RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is identical to the substance Imidacloprid 138261-41-3 (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine Imidacloprid C9H10ClN5O2 ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is identical to the substance Imidacloprid 138261-41-3 (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine Imidacloprid C9H10ClN5O2 ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is identical to the substance Imidacloprid 138261-41-3 (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine Imidacloprid C9H10ClN5O2 ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is identical to the substance Imidacloprid 138261-41-3 (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine Imidacloprid C9H10ClN5O2 ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is identical to the substance Imidacloprid 138261-41-3 (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine Imidacloprid C9H10ClN5O2 ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is identical to the substance Imidacloprid 138261-41-3 (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine Imidacloprid C9H10ClN5O2 ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is identical to the substance Imidacloprid 138261-41-3 (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine Imidacloprid C9H10ClN5O2 ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is identical to the substance Imidacloprid 138261-41-3 (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine Imidacloprid C9H10ClN5O2 ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is identical to the substance Imidacloprid 138261-41-3 (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine Imidacloprid C9H10ClN5O2 ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is identical to the substance Imidacloprid 138261-41-3 (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine Imidacloprid C9H10ClN5O2 ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is identical to the substance Imidacloprid 138261-41-3 (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine Imidacloprid C9H10ClN5O2 ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is identical to the substance Imidacloprid 138261-41-3 (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine Imidacloprid C9H10ClN5O2 ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is identical to the substance Imidacloprid 138261-41-3 (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine Imidacloprid C9H10ClN5O2 ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is identical to the substance Imidacloprid 138261-41-3 (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine Imidacloprid C9H10ClN5O2 ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is identical to the substance Imidacloprid 138261-41-3 (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine Imidacloprid C9H10ClN5O2 ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is identical to the substance Imidacloprid 138261-41-3 (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine Imidacloprid C9H10ClN5O2 ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is identical to the substance Imidacloprid 138261-41-3 (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine Imidacloprid C9H10ClN5O2 ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is identical to the substance Imidacloprid 138261-41-3 (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine Imidacloprid C9H10ClN5O2 ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is identical to the substance Imidacloprid 138261-41-3 (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine Imidacloprid C9H10ClN5O2 ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is identical to the substance Imidacloprid 138261-41-3 (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine Imidacloprid C9H10ClN5O2 ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is identical to the substance Imidacloprid 138261-41-3 (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine Imidacloprid C9H10ClN5O2 ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is identical to the substance Imidacloprid 138261-41-3 (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine Imidacloprid C9H10ClN5O2 ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is identical to the substance Imidacloprid 138261-41-3 (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine Imidacloprid C9H10ClN5O2 ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is identical to the substance Imidacloprid 138261-41-3 (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine Imidacloprid C9H10ClN5O2 ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is identical to the substance Imidacloprid 138261-41-3 (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine Imidacloprid C9H10ClN5O2 ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is identical to the substance Imidacloprid 138261-41-3 (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine Imidacloprid C9H10ClN5O2 ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is identical to the substance Imidacloprid 138261-41-3 (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine Imidacloprid C9H10ClN5O2 ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13) organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported no data without Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is identical to the substance Imidacloprid 138261-41-3 (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine Imidacloprid C9H10ClN5O2 ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13) organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported no data with Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is identical to the substance Imidacloprid 138261-41-3 (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine Imidacloprid C9H10ClN5O2 ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13) organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported no data with Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is identical to the substance Imidacloprid 138261-41-3 (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine Imidacloprid C9H10ClN5O2 ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13) organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported no data without Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is identical to the substance Imidacloprid 138261-41-3 (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine Imidacloprid C9H10ClN5O2 ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported no data without Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is identical to the substance Imidacloprid 138261-41-3 (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine Imidacloprid C9H10ClN5O2 ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported no data with Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is identical to the substance Imidacloprid 138261-41-3 (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine Imidacloprid C9H10ClN5O2 ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13) organic compound Other Other genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro According to OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay) No Acceptable Saccharomyces cerevisiae (as organism) D7 Not reported no data without Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is identical to the substance Imidacloprid 138261-41-3 (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine Imidacloprid C9H10ClN5O2 ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13) organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported no data without Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is identical to the substance Imidacloprid 138261-41-3 (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine Imidacloprid C9H10ClN5O2 ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13) organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro According to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No Acceptable Hamster (as animal) CHO Not reported no data with Positive RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is identical to the substance Imidacloprid 138261-41-3 (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine Imidacloprid C9H10ClN5O2 ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13) organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro According to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No Acceptable Hamster (as animal) CHO Not reported no data without Positive RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is identical to the substance Imidacloprid 138261-41-3 (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine Imidacloprid C9H10ClN5O2 ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13) organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro According to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No Acceptable Hamster (as animal) CHO Not reported no data without Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is identical to the substance Imidacloprid 138261-41-3 (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine Imidacloprid C9H10ClN5O2 ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13) organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro According to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No Acceptable Hamster (as animal) CHO Not reported no data with Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is identical to the substance Imidacloprid 138261-41-3 (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine Imidacloprid C9H10ClN5O2 ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported no data with Positive RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is identical to the substance Imidacloprid 138261-41-3 (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine Imidacloprid C9H10ClN5O2 ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported no data without Positive RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is identical to the substance Imidacloprid 138261-41-3 (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine Imidacloprid C9H10ClN5O2 ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13) organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Hamster (as animal) Not reported No data oral: unspecified 6.0000000000 h no data not applicable Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is identical to the substance Imidacloprid 138261-41-3 (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine Imidacloprid C9H10ClN5O2 ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13) organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Hamster (as animal) Not reported No data oral: unspecified 24.0000000000 h no data not applicable Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is identical to the substance Imidacloprid 138261-41-3 (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine Imidacloprid C9H10ClN5O2 ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13) organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Hamster (as animal) Not reported No data oral: unspecified 48.0000000000 h no data not applicable Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is identical to the substance Imidacloprid 138261-41-3 (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine Imidacloprid C9H10ClN5O2 ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI No data oral: unspecified 48.0000000000 h no data not applicable Negative indirect evidence-systemic toxicity RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is identical to the substance Imidacloprid 138261-41-3 (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine Imidacloprid C9H10ClN5O2 ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI No data oral: unspecified 72.0000000000 h no data not applicable Negative indirect evidence-systemic toxicity RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is identical to the substance Imidacloprid 138261-41-3 (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine Imidacloprid C9H10ClN5O2 ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI No data oral: unspecified 24.0000000000 h no data not applicable Negative indirect evidence-systemic toxicity RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is identical to the substance Imidacloprid 138261-41-3 (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine Imidacloprid C9H10ClN5O2 ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13) organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vivo No guideline available Not reported Not applicable Acceptable Hamster (as animal) Not reported No data oral: unspecified 1.0000000000 D no data not applicable Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is identical to the substance Imidacloprid 138261-41-3 (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine Imidacloprid C9H10ClN5O2 ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13) organic compound Other Other chromosome aberration mammalian germ cell cytogenetic assay in vivo According to OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test) No Acceptable House mouse (as animal) NMRI Male oral: unspecified no data not applicable Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Ipconazole 125225-28-7 single chemical entity Component is identical to the substance Ipconazole 125225-28-7 2-(4-chlorobenzyl)-5-isopropyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol Ipconazole C18H24ClN3O OC1(CN3N=CN=C3)C(CC2=CC=C(Cl)C=C2)CCC1C(C)C InChI=1S/C18H24ClN3O/c1-13(2)17-8-5-15(9-14-3-6-16(19)7-4-14)18(17,23)10-22-12-20-11-21-22/h3-4,6-7,11-13,15,17,23H,5,8-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The United Kingdom Ipconazole 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ipconazole. 09Apr2013 2013 doi:10.2903/j.efsa.2013.3181
+Ipconazole 125225-28-7 single chemical entity Component is identical to the substance Ipconazole 125225-28-7 2-(4-chlorobenzyl)-5-isopropyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol Ipconazole C18H24ClN3O OC1(CN3N=CN=C3)C(CC2=CC=C(Cl)C=C2)CCC1C(C)C InChI=1S/C18H24ClN3O/c1-13(2)17-8-5-15(9-14-3-6-16(19)7-4-14)18(17,23)10-22-12-20-11-21-22/h3-4,6-7,11-13,15,17,23H,5,8-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The United Kingdom Ipconazole 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ipconazole. 09Apr2013 2013 doi:10.2903/j.efsa.2013.3181
+Ipconazole 125225-28-7 single chemical entity Component is identical to the substance Ipconazole 125225-28-7 2-(4-chlorobenzyl)-5-isopropyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol Ipconazole C18H24ClN3O OC1(CN3N=CN=C3)C(CC2=CC=C(Cl)C=C2)CCC1C(C)C InChI=1S/C18H24ClN3O/c1-13(2)17-8-5-15(9-14-3-6-16(19)7-4-14)18(17,23)10-22-12-20-11-21-22/h3-4,6-7,11-13,15,17,23H,5,8-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The United Kingdom Ipconazole 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ipconazole. 09Apr2013 2013 doi:10.2903/j.efsa.2013.3181
+Ipconazole 125225-28-7 single chemical entity Component is identical to the substance Ipconazole 125225-28-7 2-(4-chlorobenzyl)-5-isopropyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol Ipconazole C18H24ClN3O OC1(CN3N=CN=C3)C(CC2=CC=C(Cl)C=C2)CCC1C(C)C InChI=1S/C18H24ClN3O/c1-13(2)17-8-5-15(9-14-3-6-16(19)7-4-14)18(17,23)10-22-12-20-11-21-22/h3-4,6-7,11-13,15,17,23H,5,8-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The United Kingdom Ipconazole 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ipconazole. 09Apr2013 2013 doi:10.2903/j.efsa.2013.3181
+Ipconazole 125225-28-7 single chemical entity Component is identical to the substance Ipconazole 125225-28-7 2-(4-chlorobenzyl)-5-isopropyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol Ipconazole C18H24ClN3O OC1(CN3N=CN=C3)C(CC2=CC=C(Cl)C=C2)CCC1C(C)C InChI=1S/C18H24ClN3O/c1-13(2)17-8-5-15(9-14-3-6-16(19)7-4-14)18(17,23)10-22-12-20-11-21-22/h3-4,6-7,11-13,15,17,23H,5,8-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The United Kingdom Ipconazole 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ipconazole. 09Apr2013 2013 doi:10.2903/j.efsa.2013.3181
+Ipconazole 125225-28-7 single chemical entity Component is identical to the substance Ipconazole 125225-28-7 2-(4-chlorobenzyl)-5-isopropyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol Ipconazole C18H24ClN3O OC1(CN3N=CN=C3)C(CC2=CC=C(Cl)C=C2)CCC1C(C)C InChI=1S/C18H24ClN3O/c1-13(2)17-8-5-15(9-14-3-6-16(19)7-4-14)18(17,23)10-22-12-20-11-21-22/h3-4,6-7,11-13,15,17,23H,5,8-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: The United Kingdom Ipconazole 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ipconazole. 09Apr2013 2013 doi:10.2903/j.efsa.2013.3181
+Ipconazole 125225-28-7 single chemical entity Component is identical to the substance Ipconazole 125225-28-7 2-(4-chlorobenzyl)-5-isopropyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol Ipconazole C18H24ClN3O OC1(CN3N=CN=C3)C(CC2=CC=C(Cl)C=C2)CCC1C(C)C InChI=1S/C18H24ClN3O/c1-13(2)17-8-5-15(9-14-3-6-16(19)7-4-14)18(17,23)10-22-12-20-11-21-22/h3-4,6-7,11-13,15,17,23H,5,8-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The United Kingdom Ipconazole 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ipconazole. 09Apr2013 2013 doi:10.2903/j.efsa.2013.3181
+Ipconazole 125225-28-7 single chemical entity Component is identical to the substance Ipconazole 125225-28-7 2-(4-chlorobenzyl)-5-isopropyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol Ipconazole C18H24ClN3O OC1(CN3N=CN=C3)C(CC2=CC=C(Cl)C=C2)CCC1C(C)C InChI=1S/C18H24ClN3O/c1-13(2)17-8-5-15(9-14-3-6-16(19)7-4-14)18(17,23)10-22-12-20-11-21-22/h3-4,6-7,11-13,15,17,23H,5,8-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The United Kingdom Ipconazole 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ipconazole. 09Apr2013 2013 doi:10.2903/j.efsa.2013.3181
+Ipconazole 125225-28-7 single chemical entity Component is identical to the substance Ipconazole 125225-28-7 2-(4-chlorobenzyl)-5-isopropyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol Ipconazole C18H24ClN3O OC1(CN3N=CN=C3)C(CC2=CC=C(Cl)C=C2)CCC1C(C)C InChI=1S/C18H24ClN3O/c1-13(2)17-8-5-15(9-14-3-6-16(19)7-4-14)18(17,23)10-22-12-20-11-21-22/h3-4,6-7,11-13,15,17,23H,5,8-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: The United Kingdom Ipconazole 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ipconazole. 09Apr2013 2013 doi:10.2903/j.efsa.2013.3181
+Ipconazole 125225-28-7 single chemical entity Component is identical to the substance Ipconazole 125225-28-7 2-(4-chlorobenzyl)-5-isopropyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol Ipconazole C18H24ClN3O OC1(CN3N=CN=C3)C(CC2=CC=C(Cl)C=C2)CCC1C(C)C InChI=1S/C18H24ClN3O/c1-13(2)17-8-5-15(9-14-3-6-16(19)7-4-14)18(17,23)10-22-12-20-11-21-22/h3-4,6-7,11-13,15,17,23H,5,8-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The United Kingdom Ipconazole 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ipconazole. 09Apr2013 2013 doi:10.2903/j.efsa.2013.3181
+Ipconazole 125225-28-7 single chemical entity Component is identical to the substance Ipconazole 125225-28-7 2-(4-chlorobenzyl)-5-isopropyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol Ipconazole C18H24ClN3O OC1(CN3N=CN=C3)C(CC2=CC=C(Cl)C=C2)CCC1C(C)C InChI=1S/C18H24ClN3O/c1-13(2)17-8-5-15(9-14-3-6-16(19)7-4-14)18(17,23)10-22-12-20-11-21-22/h3-4,6-7,11-13,15,17,23H,5,8-10H2,1-2H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Inconclusive RMS: The United Kingdom Ipconazole 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ipconazole. 09Apr2013 2013 doi:10.2903/j.efsa.2013.3181
+Ipconazole 125225-28-7 single chemical entity Component is identical to the substance Ipconazole 125225-28-7 2-(4-chlorobenzyl)-5-isopropyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol Ipconazole C18H24ClN3O OC1(CN3N=CN=C3)C(CC2=CC=C(Cl)C=C2)CCC1C(C)C InChI=1S/C18H24ClN3O/c1-13(2)17-8-5-15(9-14-3-6-16(19)7-4-14)18(17,23)10-22-12-20-11-21-22/h3-4,6-7,11-13,15,17,23H,5,8-10H2,1-2H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Inconclusive RMS: The United Kingdom Ipconazole 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ipconazole. 09Apr2013 2013 doi:10.2903/j.efsa.2013.3181
+Ipconazole 125225-28-7 single chemical entity Component is identical to the substance Ipconazole 125225-28-7 2-(4-chlorobenzyl)-5-isopropyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol Ipconazole C18H24ClN3O OC1(CN3N=CN=C3)C(CC2=CC=C(Cl)C=C2)CCC1C(C)C InChI=1S/C18H24ClN3O/c1-13(2)17-8-5-15(9-14-3-6-16(19)7-4-14)18(17,23)10-22-12-20-11-21-22/h3-4,6-7,11-13,15,17,23H,5,8-10H2,1-2H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, historical with Negative RMS: The United Kingdom Ipconazole 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ipconazole. 09Apr2013 2013 doi:10.2903/j.efsa.2013.3181
+Ipconazole 125225-28-7 single chemical entity Component is identical to the substance Ipconazole 125225-28-7 2-(4-chlorobenzyl)-5-isopropyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol Ipconazole C18H24ClN3O OC1(CN3N=CN=C3)C(CC2=CC=C(Cl)C=C2)CCC1C(C)C InChI=1S/C18H24ClN3O/c1-13(2)17-8-5-15(9-14-3-6-16(19)7-4-14)18(17,23)10-22-12-20-11-21-22/h3-4,6-7,11-13,15,17,23H,5,8-10H2,1-2H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, historical without Negative RMS: The United Kingdom Ipconazole 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ipconazole. 09Apr2013 2013 doi:10.2903/j.efsa.2013.3181
+Ipconazole 125225-28-7 single chemical entity Component is identical to the substance Ipconazole 125225-28-7 2-(4-chlorobenzyl)-5-isopropyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol Ipconazole C18H24ClN3O OC1(CN3N=CN=C3)C(CC2=CC=C(Cl)C=C2)CCC1C(C)C InChI=1S/C18H24ClN3O/c1-13(2)17-8-5-15(9-14-3-6-16(19)7-4-14)18(17,23)10-22-12-20-11-21-22/h3-4,6-7,11-13,15,17,23H,5,8-10H2,1-2H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: The United Kingdom Ipconazole 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ipconazole. 09Apr2013 2013 doi:10.2903/j.efsa.2013.3181
+Kresoxim-methyl 143390-89-0 single chemical entity Component is identical to the substance Kresoxim-methyl 143390-89-0 methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate Kresoxim-methyl C18H19NO4 CC1=CC=CC=C1OCC2=CC=CC=C2/C(=N\OC)/C(=O)OC InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is identical to the substance Kresoxim-methyl 143390-89-0 methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate Kresoxim-methyl C18H19NO4 CC1=CC=CC=C1OCC2=CC=CC=C2/C(=N\OC)/C(=O)OC InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is identical to the substance Kresoxim-methyl 143390-89-0 methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate Kresoxim-methyl C18H19NO4 CC1=CC=CC=C1OCC2=CC=CC=C2/C(=N\OC)/C(=O)OC InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is identical to the substance Kresoxim-methyl 143390-89-0 methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate Kresoxim-methyl C18H19NO4 CC1=CC=CC=C1OCC2=CC=CC=C2/C(=N\OC)/C(=O)OC InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is identical to the substance Kresoxim-methyl 143390-89-0 methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate Kresoxim-methyl C18H19NO4 CC1=CC=CC=C1OCC2=CC=CC=C2/C(=N\OC)/C(=O)OC InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is identical to the substance Kresoxim-methyl 143390-89-0 methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate Kresoxim-methyl C18H19NO4 CC1=CC=CC=C1OCC2=CC=CC=C2/C(=N\OC)/C(=O)OC InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is identical to the substance Kresoxim-methyl 143390-89-0 methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate Kresoxim-methyl C18H19NO4 CC1=CC=CC=C1OCC2=CC=CC=C2/C(=N\OC)/C(=O)OC InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is identical to the substance Kresoxim-methyl 143390-89-0 methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate Kresoxim-methyl C18H19NO4 CC1=CC=CC=C1OCC2=CC=CC=C2/C(=N\OC)/C(=O)OC InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is identical to the substance Kresoxim-methyl 143390-89-0 methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate Kresoxim-methyl C18H19NO4 CC1=CC=CC=C1OCC2=CC=CC=C2/C(=N\OC)/C(=O)OC InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is identical to the substance Kresoxim-methyl 143390-89-0 methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate Kresoxim-methyl C18H19NO4 CC1=CC=CC=C1OCC2=CC=CC=C2/C(=N\OC)/C(=O)OC InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is identical to the substance Kresoxim-methyl 143390-89-0 methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate Kresoxim-methyl C18H19NO4 CC1=CC=CC=C1OCC2=CC=CC=C2/C(=N\OC)/C(=O)OC InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is identical to the substance Kresoxim-methyl 143390-89-0 methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate Kresoxim-methyl C18H19NO4 CC1=CC=CC=C1OCC2=CC=CC=C2/C(=N\OC)/C(=O)OC InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is identical to the substance Kresoxim-methyl 143390-89-0 methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate Kresoxim-methyl C18H19NO4 CC1=CC=CC=C1OCC2=CC=CC=C2/C(=N\OC)/C(=O)OC InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is identical to the substance Kresoxim-methyl 143390-89-0 methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate Kresoxim-methyl C18H19NO4 CC1=CC=CC=C1OCC2=CC=CC=C2/C(=N\OC)/C(=O)OC InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is identical to the substance Kresoxim-methyl 143390-89-0 methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate Kresoxim-methyl C18H19NO4 CC1=CC=CC=C1OCC2=CC=CC=C2/C(=N\OC)/C(=O)OC InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is identical to the substance Kresoxim-methyl 143390-89-0 methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate Kresoxim-methyl C18H19NO4 CC1=CC=CC=C1OCC2=CC=CC=C2/C(=N\OC)/C(=O)OC InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is identical to the substance Kresoxim-methyl 143390-89-0 methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate Kresoxim-methyl C18H19NO4 CC1=CC=CC=C1OCC2=CC=CC=C2/C(=N\OC)/C(=O)OC InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is identical to the substance Kresoxim-methyl 143390-89-0 methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate Kresoxim-methyl C18H19NO4 CC1=CC=CC=C1OCC2=CC=CC=C2/C(=N\OC)/C(=O)OC InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is identical to the substance Kresoxim-methyl 143390-89-0 methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate Kresoxim-methyl C18H19NO4 CC1=CC=CC=C1OCC2=CC=CC=C2/C(=N\OC)/C(=O)OC InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is identical to the substance Kresoxim-methyl 143390-89-0 methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate Kresoxim-methyl C18H19NO4 CC1=CC=CC=C1OCC2=CC=CC=C2/C(=N\OC)/C(=O)OC InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is identical to the substance Kresoxim-methyl 143390-89-0 methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate Kresoxim-methyl C18H19NO4 CC1=CC=CC=C1OCC2=CC=CC=C2/C(=N\OC)/C(=O)OC InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+ organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes without Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is identical to the substance Kresoxim-methyl 143390-89-0 methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate Kresoxim-methyl C18H19NO4 CC1=CC=CC=C1OCC2=CC=CC=C2/C(=N\OC)/C(=O)OC InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+ organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes with Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is identical to the substance Kresoxim-methyl 143390-89-0 methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate Kresoxim-methyl C18H19NO4 CC1=CC=CC=C1OCC2=CC=CC=C2/C(=N\OC)/C(=O)OC InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+ organic compound PubChem isomeric SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is identical to the substance Kresoxim-methyl 143390-89-0 methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate Kresoxim-methyl C18H19NO4 CC1=CC=CC=C1OCC2=CC=CC=C2/C(=N\OC)/C(=O)OC InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+ organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female intraperitoneal 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is identical to the substance Kresoxim-methyl 143390-89-0 methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate Kresoxim-methyl C18H19NO4 CC1=CC=CC=C1OCC2=CC=CC=C2/C(=N\OC)/C(=O)OC InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+ organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female intraperitoneal 16.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is identical to the substance Kresoxim-methyl 143390-89-0 methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate Kresoxim-methyl C18H19NO4 CC1=CC=CC=C1OCC2=CC=CC=C2/C(=N\OC)/C(=O)OC InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+ organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female intraperitoneal 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is identical to the substance Kresoxim-methyl 143390-89-0 methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate Kresoxim-methyl C18H19NO4 CC1=CC=CC=C1OCC2=CC=CC=C2/C(=N\OC)/C(=O)OC InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+ organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable Rat (as animal) Wistar 10 Male/Female intraperitoneal 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is identical to the substance Kresoxim-methyl 143390-89-0 methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate Kresoxim-methyl C18H19NO4 CC1=CC=CC=C1OCC2=CC=CC=C2/C(=N\OC)/C(=O)OC InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+ organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable Rat (as animal) Wistar 10 Male/Female intraperitoneal 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is identical to the substance Kresoxim-methyl 143390-89-0 methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate Kresoxim-methyl C18H19NO4 CC1=CC=CC=C1OCC2=CC=CC=C2/C(=N\OC)/C(=O)OC InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+ organic compound PubChem isomeric SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo Equivalent or similar to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) Yes Acceptable Rat (as animal) Wistar 3 Male oral: gavage 18.0000000000 h yes not applicable Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is identical to the substance Kresoxim-methyl 143390-89-0 methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate Kresoxim-methyl C18H19NO4 CC1=CC=CC=C1OCC2=CC=CC=C2/C(=N\OC)/C(=O)OC InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+ organic compound PubChem isomeric SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo Equivalent or similar to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) Yes Acceptable Rat (as animal) Wistar 16 Male oral: feed 3.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is identical to the substance Kresoxim-methyl 143390-89-0 methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate Kresoxim-methyl C18H19NO4 CC1=CC=CC=C1OCC2=CC=CC=C2/C(=N\OC)/C(=O)OC InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+ organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration mammalian germ cell cytogenetic assay in vivo According to OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test) No Acceptable House mouse (as animal) NMRI 6 Male oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is identical to the substance Kresoxim-methyl 143390-89-0 methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate Kresoxim-methyl C18H19NO4 CC1=CC=CC=C1OCC2=CC=CC=C2/C(=N\OC)/C(=O)OC InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+ organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration mammalian germ cell cytogenetic assay in vivo According to OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test) No Acceptable House mouse (as animal) NMRI 6 Male oral: unspecified 48.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is a metabolite of the substance (2E)-(2-{[2-(hydroxymethyl)phenoxy] methyl}phenyl)(methoxyimino)acetic acid (2E)-(2-{[2-(hydroxymethyl)phenoxy]methyl}phenyl)(methoxyimino)ethanoic acid Not in list C17H17NO5 OC(=O)\C(=N\OC)c2ccccc2COc1ccccc1CO InChI=1/C17H17NO5/c1-22-18-16(17(20)21)14-8-4-2-7-13(14)11-23-15-9-5-3-6-12(15)10-19/h2-9,19H,10-11H2,1H3,(H,20,21)/b18-16+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is a metabolite of the substance (2E)-(2-{[2-(hydroxymethyl)phenoxy] methyl}phenyl)(methoxyimino)acetic acid (2E)-(2-{[2-(hydroxymethyl)phenoxy]methyl}phenyl)(methoxyimino)ethanoic acid Not in list C17H17NO5 OC(=O)\C(=N\OC)c2ccccc2COc1ccccc1CO InChI=1/C17H17NO5/c1-22-18-16(17(20)21)14-8-4-2-7-13(14)11-23-15-9-5-3-6-12(15)10-19/h2-9,19H,10-11H2,1H3,(H,20,21)/b18-16+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is a metabolite of the substance (2E)-(2-{[2-(hydroxymethyl)phenoxy] methyl}phenyl)(methoxyimino)acetic acid (2E)-(2-{[2-(hydroxymethyl)phenoxy]methyl}phenyl)(methoxyimino)ethanoic acid Not in list C17H17NO5 OC(=O)\C(=N\OC)c2ccccc2COc1ccccc1CO InChI=1/C17H17NO5/c1-22-18-16(17(20)21)14-8-4-2-7-13(14)11-23-15-9-5-3-6-12(15)10-19/h2-9,19H,10-11H2,1H3,(H,20,21)/b18-16+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is a metabolite of the substance (2E)-(2-{[2-(hydroxymethyl)phenoxy] methyl}phenyl)(methoxyimino)acetic acid (2E)-(2-{[2-(hydroxymethyl)phenoxy]methyl}phenyl)(methoxyimino)ethanoic acid Not in list C17H17NO5 OC(=O)\C(=N\OC)c2ccccc2COc1ccccc1CO InChI=1/C17H17NO5/c1-22-18-16(17(20)21)14-8-4-2-7-13(14)11-23-15-9-5-3-6-12(15)10-19/h2-9,19H,10-11H2,1H3,(H,20,21)/b18-16+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is a metabolite of the substance (2E)-(2-{[2-(hydroxymethyl)phenoxy] methyl}phenyl)(methoxyimino)acetic acid (2E)-(2-{[2-(hydroxymethyl)phenoxy]methyl}phenyl)(methoxyimino)ethanoic acid Not in list C17H17NO5 OC(=O)\C(=N\OC)c2ccccc2COc1ccccc1CO InChI=1/C17H17NO5/c1-22-18-16(17(20)21)14-8-4-2-7-13(14)11-23-15-9-5-3-6-12(15)10-19/h2-9,19H,10-11H2,1H3,(H,20,21)/b18-16+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is a metabolite of the substance (2E)-(2-{[2-(hydroxymethyl)phenoxy] methyl}phenyl)(methoxyimino)acetic acid (2E)-(2-{[2-(hydroxymethyl)phenoxy]methyl}phenyl)(methoxyimino)ethanoic acid Not in list C17H17NO5 OC(=O)\C(=N\OC)c2ccccc2COc1ccccc1CO InChI=1/C17H17NO5/c1-22-18-16(17(20)21)14-8-4-2-7-13(14)11-23-15-9-5-3-6-12(15)10-19/h2-9,19H,10-11H2,1H3,(H,20,21)/b18-16+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is a metabolite of the substance (2E)-(2-{[2-(hydroxymethyl)phenoxy] methyl}phenyl)(methoxyimino)acetic acid (2E)-(2-{[2-(hydroxymethyl)phenoxy]methyl}phenyl)(methoxyimino)ethanoic acid Not in list C17H17NO5 OC(=O)\C(=N\OC)c2ccccc2COc1ccccc1CO InChI=1/C17H17NO5/c1-22-18-16(17(20)21)14-8-4-2-7-13(14)11-23-15-9-5-3-6-12(15)10-19/h2-9,19H,10-11H2,1H3,(H,20,21)/b18-16+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is a metabolite of the substance (2E)-(2-{[2-(hydroxymethyl)phenoxy] methyl}phenyl)(methoxyimino)acetic acid (2E)-(2-{[2-(hydroxymethyl)phenoxy]methyl}phenyl)(methoxyimino)ethanoic acid Not in list C17H17NO5 OC(=O)\C(=N\OC)c2ccccc2COc1ccccc1CO InChI=1/C17H17NO5/c1-22-18-16(17(20)21)14-8-4-2-7-13(14)11-23-15-9-5-3-6-12(15)10-19/h2-9,19H,10-11H2,1H3,(H,20,21)/b18-16+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is a metabolite of the substance (2E)-(2-{[2-(hydroxymethyl)phenoxy] methyl}phenyl)(methoxyimino)acetic acid (2E)-(2-{[2-(hydroxymethyl)phenoxy]methyl}phenyl)(methoxyimino)ethanoic acid Not in list C17H17NO5 OC(=O)\C(=N\OC)c2ccccc2COc1ccccc1CO InChI=1/C17H17NO5/c1-22-18-16(17(20)21)14-8-4-2-7-13(14)11-23-15-9-5-3-6-12(15)10-19/h2-9,19H,10-11H2,1H3,(H,20,21)/b18-16+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is a metabolite of the substance (2E)-(2-{[2-(hydroxymethyl)phenoxy] methyl}phenyl)(methoxyimino)acetic acid (2E)-(2-{[2-(hydroxymethyl)phenoxy]methyl}phenyl)(methoxyimino)ethanoic acid Not in list C17H17NO5 OC(=O)\C(=N\OC)c2ccccc2COc1ccccc1CO InChI=1/C17H17NO5/c1-22-18-16(17(20)21)14-8-4-2-7-13(14)11-23-15-9-5-3-6-12(15)10-19/h2-9,19H,10-11H2,1H3,(H,20,21)/b18-16+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is a metabolite of the substance (2E)-{2-[(4-hydroxy-2-methylphenoxy) methyl]phenyl}(methoxyimino)acetic acid (2E)-{2-[(4-hydroxy-2-methylphenoxy)methyl]phenyl}(methoxyimino)ethanoic acid Not in list C17H17NO5 OC(=O)\C(=N\OC)c2ccccc2COc1ccc(O)cc1C InChI=1/C17H17NO5/c1-11-9-13(19)7-8-15(11)23-10-12-5-3-4-6-14(12)16(17(20)21)18-22-2/h3-9,19H,10H2,1-2H3,(H,20,21)/b18-16+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is a metabolite of the substance (2E)-{2-[(4-hydroxy-2-methylphenoxy) methyl]phenyl}(methoxyimino)acetic acid (2E)-{2-[(4-hydroxy-2-methylphenoxy)methyl]phenyl}(methoxyimino)ethanoic acid Not in list C17H17NO5 OC(=O)\C(=N\OC)c2ccccc2COc1ccc(O)cc1C InChI=1/C17H17NO5/c1-11-9-13(19)7-8-15(11)23-10-12-5-3-4-6-14(12)16(17(20)21)18-22-2/h3-9,19H,10H2,1-2H3,(H,20,21)/b18-16+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is a metabolite of the substance (2E)-{2-[(4-hydroxy-2-methylphenoxy) methyl]phenyl}(methoxyimino)acetic acid (2E)-{2-[(4-hydroxy-2-methylphenoxy)methyl]phenyl}(methoxyimino)ethanoic acid Not in list C17H17NO5 OC(=O)\C(=N\OC)c2ccccc2COc1ccc(O)cc1C InChI=1/C17H17NO5/c1-11-9-13(19)7-8-15(11)23-10-12-5-3-4-6-14(12)16(17(20)21)18-22-2/h3-9,19H,10H2,1-2H3,(H,20,21)/b18-16+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is a metabolite of the substance (2E)-{2-[(4-hydroxy-2-methylphenoxy) methyl]phenyl}(methoxyimino)acetic acid (2E)-{2-[(4-hydroxy-2-methylphenoxy)methyl]phenyl}(methoxyimino)ethanoic acid Not in list C17H17NO5 OC(=O)\C(=N\OC)c2ccccc2COc1ccc(O)cc1C InChI=1/C17H17NO5/c1-11-9-13(19)7-8-15(11)23-10-12-5-3-4-6-14(12)16(17(20)21)18-22-2/h3-9,19H,10H2,1-2H3,(H,20,21)/b18-16+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is a metabolite of the substance (2E)-{2-[(4-hydroxy-2-methylphenoxy) methyl]phenyl}(methoxyimino)acetic acid (2E)-{2-[(4-hydroxy-2-methylphenoxy)methyl]phenyl}(methoxyimino)ethanoic acid Not in list C17H17NO5 OC(=O)\C(=N\OC)c2ccccc2COc1ccc(O)cc1C InChI=1/C17H17NO5/c1-11-9-13(19)7-8-15(11)23-10-12-5-3-4-6-14(12)16(17(20)21)18-22-2/h3-9,19H,10H2,1-2H3,(H,20,21)/b18-16+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is a metabolite of the substance (2E)-{2-[(4-hydroxy-2-methylphenoxy) methyl]phenyl}(methoxyimino)acetic acid (2E)-{2-[(4-hydroxy-2-methylphenoxy)methyl]phenyl}(methoxyimino)ethanoic acid Not in list C17H17NO5 OC(=O)\C(=N\OC)c2ccccc2COc1ccc(O)cc1C InChI=1/C17H17NO5/c1-11-9-13(19)7-8-15(11)23-10-12-5-3-4-6-14(12)16(17(20)21)18-22-2/h3-9,19H,10H2,1-2H3,(H,20,21)/b18-16+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is a metabolite of the substance (2E)-{2-[(4-hydroxy-2-methylphenoxy) methyl]phenyl}(methoxyimino)acetic acid (2E)-{2-[(4-hydroxy-2-methylphenoxy)methyl]phenyl}(methoxyimino)ethanoic acid Not in list C17H17NO5 OC(=O)\C(=N\OC)c2ccccc2COc1ccc(O)cc1C InChI=1/C17H17NO5/c1-11-9-13(19)7-8-15(11)23-10-12-5-3-4-6-14(12)16(17(20)21)18-22-2/h3-9,19H,10H2,1-2H3,(H,20,21)/b18-16+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is a metabolite of the substance (2E)-{2-[(4-hydroxy-2-methylphenoxy) methyl]phenyl}(methoxyimino)acetic acid (2E)-{2-[(4-hydroxy-2-methylphenoxy)methyl]phenyl}(methoxyimino)ethanoic acid Not in list C17H17NO5 OC(=O)\C(=N\OC)c2ccccc2COc1ccc(O)cc1C InChI=1/C17H17NO5/c1-11-9-13(19)7-8-15(11)23-10-12-5-3-4-6-14(12)16(17(20)21)18-22-2/h3-9,19H,10H2,1-2H3,(H,20,21)/b18-16+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is a metabolite of the substance (2E)-{2-[(4-hydroxy-2-methylphenoxy) methyl]phenyl}(methoxyimino)acetic acid (2E)-{2-[(4-hydroxy-2-methylphenoxy)methyl]phenyl}(methoxyimino)ethanoic acid Not in list C17H17NO5 OC(=O)\C(=N\OC)c2ccccc2COc1ccc(O)cc1C InChI=1/C17H17NO5/c1-11-9-13(19)7-8-15(11)23-10-12-5-3-4-6-14(12)16(17(20)21)18-22-2/h3-9,19H,10H2,1-2H3,(H,20,21)/b18-16+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is a metabolite of the substance (2E)-{2-[(4-hydroxy-2-methylphenoxy) methyl]phenyl}(methoxyimino)acetic acid (2E)-{2-[(4-hydroxy-2-methylphenoxy)methyl]phenyl}(methoxyimino)ethanoic acid Not in list C17H17NO5 OC(=O)\C(=N\OC)c2ccccc2COc1ccc(O)cc1C InChI=1/C17H17NO5/c1-11-9-13(19)7-8-15(11)23-10-12-5-3-4-6-14(12)16(17(20)21)18-22-2/h3-9,19H,10H2,1-2H3,(H,20,21)/b18-16+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is a metabolite of the substance 2-[2-(5-hydroxy-2-methylphenoxymethyl)phenyl]-2-methoxyiminoacetic acid (2E)-{2-[(5-hydroxy-2-methylphenoxy)methyl]phenyl}(methoxyimino)ethanoic acid Not in list C17H17NO5 O=C(O)\C(=N\OC)c2ccccc2COc1cc(O)ccc1C InChI=1/C17H17NO5/c1-11-7-8-13(19)9-15(11)23-10-12-5-3-4-6-14(12)16(17(20)21)18-22-2/h3-9,19H,10H2,1-2H3,(H,20,21)/b18-16+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is a metabolite of the substance 2-[2-(5-hydroxy-2-methylphenoxymethyl)phenyl]-2-methoxyiminoacetic acid (2E)-{2-[(5-hydroxy-2-methylphenoxy)methyl]phenyl}(methoxyimino)ethanoic acid Not in list C17H17NO5 O=C(O)\C(=N\OC)c2ccccc2COc1cc(O)ccc1C InChI=1/C17H17NO5/c1-11-7-8-13(19)9-15(11)23-10-12-5-3-4-6-14(12)16(17(20)21)18-22-2/h3-9,19H,10H2,1-2H3,(H,20,21)/b18-16+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is a metabolite of the substance 2-[2-(5-hydroxy-2-methylphenoxymethyl)phenyl]-2-methoxyiminoacetic acid (2E)-{2-[(5-hydroxy-2-methylphenoxy)methyl]phenyl}(methoxyimino)ethanoic acid Not in list C17H17NO5 O=C(O)\C(=N\OC)c2ccccc2COc1cc(O)ccc1C InChI=1/C17H17NO5/c1-11-7-8-13(19)9-15(11)23-10-12-5-3-4-6-14(12)16(17(20)21)18-22-2/h3-9,19H,10H2,1-2H3,(H,20,21)/b18-16+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is a metabolite of the substance 2-[2-(5-hydroxy-2-methylphenoxymethyl)phenyl]-2-methoxyiminoacetic acid (2E)-{2-[(5-hydroxy-2-methylphenoxy)methyl]phenyl}(methoxyimino)ethanoic acid Not in list C17H17NO5 O=C(O)\C(=N\OC)c2ccccc2COc1cc(O)ccc1C InChI=1/C17H17NO5/c1-11-7-8-13(19)9-15(11)23-10-12-5-3-4-6-14(12)16(17(20)21)18-22-2/h3-9,19H,10H2,1-2H3,(H,20,21)/b18-16+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is a metabolite of the substance 2-[2-(5-hydroxy-2-methylphenoxymethyl)phenyl]-2-methoxyiminoacetic acid (2E)-{2-[(5-hydroxy-2-methylphenoxy)methyl]phenyl}(methoxyimino)ethanoic acid Not in list C17H17NO5 O=C(O)\C(=N\OC)c2ccccc2COc1cc(O)ccc1C InChI=1/C17H17NO5/c1-11-7-8-13(19)9-15(11)23-10-12-5-3-4-6-14(12)16(17(20)21)18-22-2/h3-9,19H,10H2,1-2H3,(H,20,21)/b18-16+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is a metabolite of the substance 2-[2-(5-hydroxy-2-methylphenoxymethyl)phenyl]-2-methoxyiminoacetic acid (2E)-{2-[(5-hydroxy-2-methylphenoxy)methyl]phenyl}(methoxyimino)ethanoic acid Not in list C17H17NO5 O=C(O)\C(=N\OC)c2ccccc2COc1cc(O)ccc1C InChI=1/C17H17NO5/c1-11-7-8-13(19)9-15(11)23-10-12-5-3-4-6-14(12)16(17(20)21)18-22-2/h3-9,19H,10H2,1-2H3,(H,20,21)/b18-16+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is a metabolite of the substance 2-[2-(5-hydroxy-2-methylphenoxymethyl)phenyl]-2-methoxyiminoacetic acid (2E)-{2-[(5-hydroxy-2-methylphenoxy)methyl]phenyl}(methoxyimino)ethanoic acid Not in list C17H17NO5 O=C(O)\C(=N\OC)c2ccccc2COc1cc(O)ccc1C InChI=1/C17H17NO5/c1-11-7-8-13(19)9-15(11)23-10-12-5-3-4-6-14(12)16(17(20)21)18-22-2/h3-9,19H,10H2,1-2H3,(H,20,21)/b18-16+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is a metabolite of the substance 2-[2-(5-hydroxy-2-methylphenoxymethyl)phenyl]-2-methoxyiminoacetic acid (2E)-{2-[(5-hydroxy-2-methylphenoxy)methyl]phenyl}(methoxyimino)ethanoic acid Not in list C17H17NO5 O=C(O)\C(=N\OC)c2ccccc2COc1cc(O)ccc1C InChI=1/C17H17NO5/c1-11-7-8-13(19)9-15(11)23-10-12-5-3-4-6-14(12)16(17(20)21)18-22-2/h3-9,19H,10H2,1-2H3,(H,20,21)/b18-16+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is a metabolite of the substance 2-[2-(5-hydroxy-2-methylphenoxymethyl)phenyl]-2-methoxyiminoacetic acid (2E)-{2-[(5-hydroxy-2-methylphenoxy)methyl]phenyl}(methoxyimino)ethanoic acid Not in list C17H17NO5 O=C(O)\C(=N\OC)c2ccccc2COc1cc(O)ccc1C InChI=1/C17H17NO5/c1-11-7-8-13(19)9-15(11)23-10-12-5-3-4-6-14(12)16(17(20)21)18-22-2/h3-9,19H,10H2,1-2H3,(H,20,21)/b18-16+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is a metabolite of the substance 2-[2-(5-hydroxy-2-methylphenoxymethyl)phenyl]-2-methoxyiminoacetic acid (2E)-{2-[(5-hydroxy-2-methylphenoxy)methyl]phenyl}(methoxyimino)ethanoic acid Not in list C17H17NO5 O=C(O)\C(=N\OC)c2ccccc2COc1cc(O)ccc1C InChI=1/C17H17NO5/c1-11-7-8-13(19)9-15(11)23-10-12-5-3-4-6-14(12)16(17(20)21)18-22-2/h3-9,19H,10H2,1-2H3,(H,20,21)/b18-16+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Iprovalicarb 604-209-3 single chemical entity Component is identical to the substance Iprovalicarb 604-209-3 propan-2-yl N-[(2R)-3-methyl-1-[1-(4-methylphenyl)ethylamino]-1-oxobutan-2-yl]carbamate Iprovalicarb C18H28N2O3 CC1=CC=C(C=C1)C(C)NC(=O)C(C(C)C)NC(=O)OC(C)C InChI=1S/C18H28N2O3/c1-11(2)16(20-18(22)23-12(3)4)17(21)19-14(6)15-9-7-13(5)8-10-15/h7-12,14,16H,1-6H3,(H,19,21)(H,20,22)/t14?,16-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Ireland Iprovalicarb 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb 14Apr2015 2015 doi:10.2903/j.efsa.2015.4060
+Iprovalicarb 604-209-3 single chemical entity Component is identical to the substance Iprovalicarb 604-209-3 propan-2-yl N-[(2R)-3-methyl-1-[1-(4-methylphenyl)ethylamino]-1-oxobutan-2-yl]carbamate Iprovalicarb C18H28N2O3 CC1=CC=C(C=C1)C(C)NC(=O)C(C(C)C)NC(=O)OC(C)C InChI=1S/C18H28N2O3/c1-11(2)16(20-18(22)23-12(3)4)17(21)19-14(6)15-9-7-13(5)8-10-15/h7-12,14,16H,1-6H3,(H,19,21)(H,20,22)/t14?,16-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Ireland Iprovalicarb 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb 14Apr2015 2015 doi:10.2903/j.efsa.2015.4060
+Iprovalicarb 604-209-3 single chemical entity Component is identical to the substance Iprovalicarb 604-209-3 propan-2-yl N-[(2R)-3-methyl-1-[1-(4-methylphenyl)ethylamino]-1-oxobutan-2-yl]carbamate Iprovalicarb C18H28N2O3 CC1=CC=C(C=C1)C(C)NC(=O)C(C(C)C)NC(=O)OC(C)C InChI=1S/C18H28N2O3/c1-11(2)16(20-18(22)23-12(3)4)17(21)19-14(6)15-9-7-13(5)8-10-15/h7-12,14,16H,1-6H3,(H,19,21)(H,20,22)/t14?,16-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Ireland Iprovalicarb 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb 14Apr2015 2015 doi:10.2903/j.efsa.2015.4060
+Iprovalicarb 604-209-3 single chemical entity Component is identical to the substance Iprovalicarb 604-209-3 propan-2-yl N-[(2R)-3-methyl-1-[1-(4-methylphenyl)ethylamino]-1-oxobutan-2-yl]carbamate Iprovalicarb C18H28N2O3 CC1=CC=C(C=C1)C(C)NC(=O)C(C(C)C)NC(=O)OC(C)C InChI=1S/C18H28N2O3/c1-11(2)16(20-18(22)23-12(3)4)17(21)19-14(6)15-9-7-13(5)8-10-15/h7-12,14,16H,1-6H3,(H,19,21)(H,20,22)/t14?,16-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Ireland Iprovalicarb 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb 14Apr2015 2015 doi:10.2903/j.efsa.2015.4060
+Iprovalicarb 604-209-3 single chemical entity Component is identical to the substance Iprovalicarb 604-209-3 propan-2-yl N-[(2R)-3-methyl-1-[1-(4-methylphenyl)ethylamino]-1-oxobutan-2-yl]carbamate Iprovalicarb C18H28N2O3 CC1=CC=C(C=C1)C(C)NC(=O)C(C(C)C)NC(=O)OC(C)C InChI=1S/C18H28N2O3/c1-11(2)16(20-18(22)23-12(3)4)17(21)19-14(6)15-9-7-13(5)8-10-15/h7-12,14,16H,1-6H3,(H,19,21)(H,20,22)/t14?,16-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Ireland Iprovalicarb 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb 14Apr2015 2015 doi:10.2903/j.efsa.2015.4060
+Iprovalicarb 604-209-3 single chemical entity Component is identical to the substance Iprovalicarb 604-209-3 propan-2-yl N-[(2R)-3-methyl-1-[1-(4-methylphenyl)ethylamino]-1-oxobutan-2-yl]carbamate Iprovalicarb C18H28N2O3 CC1=CC=C(C=C1)C(C)NC(=O)C(C(C)C)NC(=O)OC(C)C InChI=1S/C18H28N2O3/c1-11(2)16(20-18(22)23-12(3)4)17(21)19-14(6)15-9-7-13(5)8-10-15/h7-12,14,16H,1-6H3,(H,19,21)(H,20,22)/t14?,16-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Ireland Iprovalicarb 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb 14Apr2015 2015 doi:10.2903/j.efsa.2015.4060
+Iprovalicarb 604-209-3 single chemical entity Component is identical to the substance Iprovalicarb 604-209-3 propan-2-yl N-[(2R)-3-methyl-1-[1-(4-methylphenyl)ethylamino]-1-oxobutan-2-yl]carbamate Iprovalicarb C18H28N2O3 CC1=CC=C(C=C1)C(C)NC(=O)C(C(C)C)NC(=O)OC(C)C InChI=1S/C18H28N2O3/c1-11(2)16(20-18(22)23-12(3)4)17(21)19-14(6)15-9-7-13(5)8-10-15/h7-12,14,16H,1-6H3,(H,19,21)(H,20,22)/t14?,16-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Ireland Iprovalicarb 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb 14Apr2015 2015 doi:10.2903/j.efsa.2015.4060
+Iprovalicarb 604-209-3 single chemical entity Component is identical to the substance Iprovalicarb 604-209-3 propan-2-yl N-[(2R)-3-methyl-1-[1-(4-methylphenyl)ethylamino]-1-oxobutan-2-yl]carbamate Iprovalicarb C18H28N2O3 CC1=CC=C(C=C1)C(C)NC(=O)C(C(C)C)NC(=O)OC(C)C InChI=1S/C18H28N2O3/c1-11(2)16(20-18(22)23-12(3)4)17(21)19-14(6)15-9-7-13(5)8-10-15/h7-12,14,16H,1-6H3,(H,19,21)(H,20,22)/t14?,16-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Ireland Iprovalicarb 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb 14Apr2015 2015 doi:10.2903/j.efsa.2015.4060
+Iprovalicarb 604-209-3 single chemical entity Component is identical to the substance Iprovalicarb 604-209-3 propan-2-yl N-[(2R)-3-methyl-1-[1-(4-methylphenyl)ethylamino]-1-oxobutan-2-yl]carbamate Iprovalicarb C18H28N2O3 CC1=CC=C(C=C1)C(C)NC(=O)C(C(C)C)NC(=O)OC(C)C InChI=1S/C18H28N2O3/c1-11(2)16(20-18(22)23-12(3)4)17(21)19-14(6)15-9-7-13(5)8-10-15/h7-12,14,16H,1-6H3,(H,19,21)(H,20,22)/t14?,16-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Ireland Iprovalicarb 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb 14Apr2015 2015 doi:10.2903/j.efsa.2015.4060
+Iprovalicarb 604-209-3 single chemical entity Component is identical to the substance Iprovalicarb 604-209-3 propan-2-yl N-[(2R)-3-methyl-1-[1-(4-methylphenyl)ethylamino]-1-oxobutan-2-yl]carbamate Iprovalicarb C18H28N2O3 CC1=CC=C(C=C1)C(C)NC(=O)C(C(C)C)NC(=O)OC(C)C InChI=1S/C18H28N2O3/c1-11(2)16(20-18(22)23-12(3)4)17(21)19-14(6)15-9-7-13(5)8-10-15/h7-12,14,16H,1-6H3,(H,19,21)(H,20,22)/t14?,16-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Ireland Iprovalicarb 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb 14Apr2015 2015 doi:10.2903/j.efsa.2015.4060
+Iprovalicarb 604-209-3 single chemical entity Component is identical to the substance Iprovalicarb 604-209-3 propan-2-yl N-[(2R)-3-methyl-1-[1-(4-methylphenyl)ethylamino]-1-oxobutan-2-yl]carbamate Iprovalicarb C18H28N2O3 CC1=CC=C(C=C1)C(C)NC(=O)C(C(C)C)NC(=O)OC(C)C InChI=1S/C18H28N2O3/c1-11(2)16(20-18(22)23-12(3)4)17(21)19-14(6)15-9-7-13(5)8-10-15/h7-12,14,16H,1-6H3,(H,19,21)(H,20,22)/t14?,16-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Ireland Iprovalicarb 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb 14Apr2015 2015 doi:10.2903/j.efsa.2015.4060
+Iprovalicarb 604-209-3 single chemical entity Component is identical to the substance Iprovalicarb 604-209-3 propan-2-yl N-[(2R)-3-methyl-1-[1-(4-methylphenyl)ethylamino]-1-oxobutan-2-yl]carbamate Iprovalicarb C18H28N2O3 CC1=CC=C(C=C1)C(C)NC(=O)C(C(C)C)NC(=O)OC(C)C InChI=1S/C18H28N2O3/c1-11(2)16(20-18(22)23-12(3)4)17(21)19-14(6)15-9-7-13(5)8-10-15/h7-12,14,16H,1-6H3,(H,19,21)(H,20,22)/t14?,16-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Ireland Iprovalicarb 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb 14Apr2015 2015 doi:10.2903/j.efsa.2015.4060
+Iprovalicarb 604-209-3 single chemical entity Component is identical to the substance Iprovalicarb 604-209-3 propan-2-yl N-[(2R)-3-methyl-1-[1-(4-methylphenyl)ethylamino]-1-oxobutan-2-yl]carbamate Iprovalicarb C18H28N2O3 CC1=CC=C(C=C1)C(C)NC(=O)C(C(C)C)NC(=O)OC(C)C InChI=1S/C18H28N2O3/c1-11(2)16(20-18(22)23-12(3)4)17(21)19-14(6)15-9-7-13(5)8-10-15/h7-12,14,16H,1-6H3,(H,19,21)(H,20,22)/t14?,16-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Ireland Iprovalicarb 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb 14Apr2015 2015 doi:10.2903/j.efsa.2015.4060
+Iprovalicarb 604-209-3 single chemical entity Component is identical to the substance Iprovalicarb 604-209-3 propan-2-yl N-[(2R)-3-methyl-1-[1-(4-methylphenyl)ethylamino]-1-oxobutan-2-yl]carbamate Iprovalicarb C18H28N2O3 CC1=CC=C(C=C1)C(C)NC(=O)C(C(C)C)NC(=O)OC(C)C InChI=1S/C18H28N2O3/c1-11(2)16(20-18(22)23-12(3)4)17(21)19-14(6)15-9-7-13(5)8-10-15/h7-12,14,16H,1-6H3,(H,19,21)(H,20,22)/t14?,16-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Ireland Iprovalicarb 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb 14Apr2015 2015 doi:10.2903/j.efsa.2015.4060
+Iprovalicarb 604-209-3 single chemical entity Component is identical to the substance Iprovalicarb 604-209-3 propan-2-yl N-[(2R)-3-methyl-1-[1-(4-methylphenyl)ethylamino]-1-oxobutan-2-yl]carbamate Iprovalicarb C18H28N2O3 CC1=CC=C(C=C1)C(C)NC(=O)C(C(C)C)NC(=O)OC(C)C InChI=1S/C18H28N2O3/c1-11(2)16(20-18(22)23-12(3)4)17(21)19-14(6)15-9-7-13(5)8-10-15/h7-12,14,16H,1-6H3,(H,19,21)(H,20,22)/t14?,16-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Ireland Iprovalicarb 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb 14Apr2015 2015 doi:10.2903/j.efsa.2015.4060
+Iprovalicarb 604-209-3 single chemical entity Component is identical to the substance Iprovalicarb 604-209-3 propan-2-yl N-[(2R)-3-methyl-1-[1-(4-methylphenyl)ethylamino]-1-oxobutan-2-yl]carbamate Iprovalicarb C18H28N2O3 CC1=CC=C(C=C1)C(C)NC(=O)C(C(C)C)NC(=O)OC(C)C InChI=1S/C18H28N2O3/c1-11(2)16(20-18(22)23-12(3)4)17(21)19-14(6)15-9-7-13(5)8-10-15/h7-12,14,16H,1-6H3,(H,19,21)(H,20,22)/t14?,16-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Ireland Iprovalicarb 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb 14Apr2015 2015 doi:10.2903/j.efsa.2015.4060
+Iprovalicarb 604-209-3 single chemical entity Component is identical to the substance Iprovalicarb 604-209-3 propan-2-yl N-[(2R)-3-methyl-1-[1-(4-methylphenyl)ethylamino]-1-oxobutan-2-yl]carbamate Iprovalicarb C18H28N2O3 CC1=CC=C(C=C1)C(C)NC(=O)C(C(C)C)NC(=O)OC(C)C InChI=1S/C18H28N2O3/c1-11(2)16(20-18(22)23-12(3)4)17(21)19-14(6)15-9-7-13(5)8-10-15/h7-12,14,16H,1-6H3,(H,19,21)(H,20,22)/t14?,16-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Ireland Iprovalicarb 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb 14Apr2015 2015 doi:10.2903/j.efsa.2015.4060
+Iprovalicarb 604-209-3 single chemical entity Component is identical to the substance Iprovalicarb 604-209-3 propan-2-yl N-[(2R)-3-methyl-1-[1-(4-methylphenyl)ethylamino]-1-oxobutan-2-yl]carbamate Iprovalicarb C18H28N2O3 CC1=CC=C(C=C1)C(C)NC(=O)C(C(C)C)NC(=O)OC(C)C InChI=1S/C18H28N2O3/c1-11(2)16(20-18(22)23-12(3)4)17(21)19-14(6)15-9-7-13(5)8-10-15/h7-12,14,16H,1-6H3,(H,19,21)(H,20,22)/t14?,16-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Ireland Iprovalicarb 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb 14Apr2015 2015 doi:10.2903/j.efsa.2015.4060
+Iprovalicarb 604-209-3 single chemical entity Component is identical to the substance Iprovalicarb 604-209-3 propan-2-yl N-[(2R)-3-methyl-1-[1-(4-methylphenyl)ethylamino]-1-oxobutan-2-yl]carbamate Iprovalicarb C18H28N2O3 CC1=CC=C(C=C1)C(C)NC(=O)C(C(C)C)NC(=O)OC(C)C InChI=1S/C18H28N2O3/c1-11(2)16(20-18(22)23-12(3)4)17(21)19-14(6)15-9-7-13(5)8-10-15/h7-12,14,16H,1-6H3,(H,19,21)(H,20,22)/t14?,16-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Ireland Iprovalicarb 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb 14Apr2015 2015 doi:10.2903/j.efsa.2015.4060
+Iprovalicarb 604-209-3 single chemical entity Component is identical to the substance Iprovalicarb 604-209-3 propan-2-yl N-[(2R)-3-methyl-1-[1-(4-methylphenyl)ethylamino]-1-oxobutan-2-yl]carbamate Iprovalicarb C18H28N2O3 CC1=CC=C(C=C1)C(C)NC(=O)C(C(C)C)NC(=O)OC(C)C InChI=1S/C18H28N2O3/c1-11(2)16(20-18(22)23-12(3)4)17(21)19-14(6)15-9-7-13(5)8-10-15/h7-12,14,16H,1-6H3,(H,19,21)(H,20,22)/t14?,16-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Ireland Iprovalicarb 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb 14Apr2015 2015 doi:10.2903/j.efsa.2015.4060
+Iprovalicarb 604-209-3 single chemical entity Component is identical to the substance Iprovalicarb 604-209-3 propan-2-yl N-[(2R)-3-methyl-1-[1-(4-methylphenyl)ethylamino]-1-oxobutan-2-yl]carbamate Iprovalicarb C18H28N2O3 CC1=CC=C(C=C1)C(C)NC(=O)C(C(C)C)NC(=O)OC(C)C InChI=1S/C18H28N2O3/c1-11(2)16(20-18(22)23-12(3)4)17(21)19-14(6)15-9-7-13(5)8-10-15/h7-12,14,16H,1-6H3,(H,19,21)(H,20,22)/t14?,16-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: Ireland Iprovalicarb 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb 14Apr2015 2015 doi:10.2903/j.efsa.2015.4060
+Iprovalicarb 604-209-3 single chemical entity Component is identical to the substance Iprovalicarb 604-209-3 propan-2-yl N-[(2R)-3-methyl-1-[1-(4-methylphenyl)ethylamino]-1-oxobutan-2-yl]carbamate Iprovalicarb C18H28N2O3 CC1=CC=C(C=C1)C(C)NC(=O)C(C(C)C)NC(=O)OC(C)C InChI=1S/C18H28N2O3/c1-11(2)16(20-18(22)23-12(3)4)17(21)19-14(6)15-9-7-13(5)8-10-15/h7-12,14,16H,1-6H3,(H,19,21)(H,20,22)/t14?,16-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: Ireland Iprovalicarb 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb 14Apr2015 2015 doi:10.2903/j.efsa.2015.4060
+Iprovalicarb 604-209-3 single chemical entity Component is identical to the substance Iprovalicarb 604-209-3 propan-2-yl N-[(2R)-3-methyl-1-[1-(4-methylphenyl)ethylamino]-1-oxobutan-2-yl]carbamate Iprovalicarb C18H28N2O3 CC1=CC=C(C=C1)C(C)NC(=O)C(C(C)C)NC(=O)OC(C)C InChI=1S/C18H28N2O3/c1-11(2)16(20-18(22)23-12(3)4)17(21)19-14(6)15-9-7-13(5)8-10-15/h7-12,14,16H,1-6H3,(H,19,21)(H,20,22)/t14?,16-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: Ireland Iprovalicarb 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb 14Apr2015 2015 doi:10.2903/j.efsa.2015.4060
+Iprovalicarb 604-209-3 single chemical entity Component is identical to the substance Iprovalicarb 604-209-3 propan-2-yl N-[(2R)-3-methyl-1-[1-(4-methylphenyl)ethylamino]-1-oxobutan-2-yl]carbamate Iprovalicarb C18H28N2O3 CC1=CC=C(C=C1)C(C)NC(=O)C(C(C)C)NC(=O)OC(C)C InChI=1S/C18H28N2O3/c1-11(2)16(20-18(22)23-12(3)4)17(21)19-14(6)15-9-7-13(5)8-10-15/h7-12,14,16H,1-6H3,(H,19,21)(H,20,22)/t14?,16-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: Ireland Iprovalicarb 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb 14Apr2015 2015 doi:10.2903/j.efsa.2015.4060
+Iprovalicarb 604-209-3 single chemical entity Component is identical to the substance Iprovalicarb 604-209-3 propan-2-yl N-[(2R)-3-methyl-1-[1-(4-methylphenyl)ethylamino]-1-oxobutan-2-yl]carbamate Iprovalicarb C18H28N2O3 CC1=CC=C(C=C1)C(C)NC(=O)C(C(C)C)NC(=O)OC(C)C InChI=1S/C18H28N2O3/c1-11(2)16(20-18(22)23-12(3)4)17(21)19-14(6)15-9-7-13(5)8-10-15/h7-12,14,16H,1-6H3,(H,19,21)(H,20,22)/t14?,16-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: Ireland Iprovalicarb 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb 14Apr2015 2015 doi:10.2903/j.efsa.2015.4060
+Iprovalicarb 604-209-3 single chemical entity Component is identical to the substance Iprovalicarb 604-209-3 propan-2-yl N-[(2R)-3-methyl-1-[1-(4-methylphenyl)ethylamino]-1-oxobutan-2-yl]carbamate Iprovalicarb C18H28N2O3 CC1=CC=C(C=C1)C(C)NC(=O)C(C(C)C)NC(=O)OC(C)C InChI=1S/C18H28N2O3/c1-11(2)16(20-18(22)23-12(3)4)17(21)19-14(6)15-9-7-13(5)8-10-15/h7-12,14,16H,1-6H3,(H,19,21)(H,20,22)/t14?,16-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes without Negative RMS: Ireland Iprovalicarb 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb 14Apr2015 2015 doi:10.2903/j.efsa.2015.4060
+Iprovalicarb 604-209-3 single chemical entity Component is identical to the substance Iprovalicarb 604-209-3 propan-2-yl N-[(2R)-3-methyl-1-[1-(4-methylphenyl)ethylamino]-1-oxobutan-2-yl]carbamate Iprovalicarb C18H28N2O3 CC1=CC=C(C=C1)C(C)NC(=O)C(C(C)C)NC(=O)OC(C)C InChI=1S/C18H28N2O3/c1-11(2)16(20-18(22)23-12(3)4)17(21)19-14(6)15-9-7-13(5)8-10-15/h7-12,14,16H,1-6H3,(H,19,21)(H,20,22)/t14?,16-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI Male/Female intraperitoneal 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Ireland Iprovalicarb 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb 14Apr2015 2015 doi:10.2903/j.efsa.2015.4060
+Iprovalicarb 604-209-3 single chemical entity Component is identical to the substance Iprovalicarb 604-209-3 propan-2-yl N-[(2R)-3-methyl-1-[1-(4-methylphenyl)ethylamino]-1-oxobutan-2-yl]carbamate Iprovalicarb C18H28N2O3 CC1=CC=C(C=C1)C(C)NC(=O)C(C(C)C)NC(=O)OC(C)C InChI=1S/C18H28N2O3/c1-11(2)16(20-18(22)23-12(3)4)17(21)19-14(6)15-9-7-13(5)8-10-15/h7-12,14,16H,1-6H3,(H,19,21)(H,20,22)/t14?,16-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI Male/Female intraperitoneal 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Ireland Iprovalicarb 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb 14Apr2015 2015 doi:10.2903/j.efsa.2015.4060
+Iprovalicarb 604-209-3 single chemical entity Component is identical to the substance Iprovalicarb 604-209-3 propan-2-yl N-[(2R)-3-methyl-1-[1-(4-methylphenyl)ethylamino]-1-oxobutan-2-yl]carbamate Iprovalicarb C18H28N2O3 CC1=CC=C(C=C1)C(C)NC(=O)C(C(C)C)NC(=O)OC(C)C InChI=1S/C18H28N2O3/c1-11(2)16(20-18(22)23-12(3)4)17(21)19-14(6)15-9-7-13(5)8-10-15/h7-12,14,16H,1-6H3,(H,19,21)(H,20,22)/t14?,16-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI Male/Female intraperitoneal 16.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Ireland Iprovalicarb 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb 14Apr2015 2015 doi:10.2903/j.efsa.2015.4060
+Iprovalicarb 604-209-3 single chemical entity Component is identical to the substance Iprovalicarb 604-209-3 propan-2-yl N-[(2R)-3-methyl-1-[1-(4-methylphenyl)ethylamino]-1-oxobutan-2-yl]carbamate Iprovalicarb C18H28N2O3 CC1=CC=C(C=C1)C(C)NC(=O)C(C(C)C)NC(=O)OC(C)C InChI=1S/C18H28N2O3/c1-11(2)16(20-18(22)23-12(3)4)17(21)19-14(6)15-9-7-13(5)8-10-15/h7-12,14,16H,1-6H3,(H,19,21)(H,20,22)/t14?,16-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable Rat (as animal) Wistar 9 Female oral: feed 7.0000000000 D yes not applicable Negative RMS: Ireland Iprovalicarb 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb 14Apr2015 2015 doi:10.2903/j.efsa.2015.4060
+Iprovalicarb 604-209-3 single chemical entity Component is identical to the substance Iprovalicarb 604-209-3 propan-2-yl N-[(2R)-3-methyl-1-[1-(4-methylphenyl)ethylamino]-1-oxobutan-2-yl]carbamate Iprovalicarb C18H28N2O3 CC1=CC=C(C=C1)C(C)NC(=O)C(C(C)C)NC(=O)OC(C)C InChI=1S/C18H28N2O3/c1-11(2)16(20-18(22)23-12(3)4)17(21)19-14(6)15-9-7-13(5)8-10-15/h7-12,14,16H,1-6H3,(H,19,21)(H,20,22)/t14?,16-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable Rat (as animal) Wistar 9 Female oral: feed 7.0000000000 D yes not applicable Negative RMS: Ireland Iprovalicarb 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb 14Apr2015 2015 doi:10.2903/j.efsa.2015.4060
+Iprovalicarb 604-209-3 single chemical entity Component is identical to the substance Iprovalicarb 604-209-3 propan-2-yl N-[(2R)-3-methyl-1-[1-(4-methylphenyl)ethylamino]-1-oxobutan-2-yl]carbamate Iprovalicarb C18H28N2O3 CC1=CC=C(C=C1)C(C)NC(=O)C(C(C)C)NC(=O)OC(C)C InChI=1S/C18H28N2O3/c1-11(2)16(20-18(22)23-12(3)4)17(21)19-14(6)15-9-7-13(5)8-10-15/h7-12,14,16H,1-6H3,(H,19,21)(H,20,22)/t14?,16-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable Rat (as animal) Wistar 9 Female oral: feed 7.0000000000 D yes not applicable Negative RMS: Ireland Iprovalicarb 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb 14Apr2015 2015 doi:10.2903/j.efsa.2015.4060
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is identical to the substance Isoxaben 407-190-8 82558-50-7 2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide Isoxaben C18H24N2O4 CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Sweden Isoxaben 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is identical to the substance Isoxaben 407-190-8 82558-50-7 2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide Isoxaben C18H24N2O4 CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Sweden Isoxaben 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is identical to the substance Isoxaben 407-190-8 82558-50-7 2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide Isoxaben C18H24N2O4 CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Sweden Isoxaben 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is identical to the substance Isoxaben 407-190-8 82558-50-7 2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide Isoxaben C18H24N2O4 CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Sweden Isoxaben 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is identical to the substance Isoxaben 407-190-8 82558-50-7 2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide Isoxaben C18H24N2O4 CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Sweden Isoxaben 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is identical to the substance Isoxaben 407-190-8 82558-50-7 2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide Isoxaben C18H24N2O4 CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Sweden Isoxaben 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is identical to the substance Isoxaben 407-190-8 82558-50-7 2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide Isoxaben C18H24N2O4 CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Sweden Isoxaben 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is identical to the substance Isoxaben 407-190-8 82558-50-7 2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide Isoxaben C18H24N2O4 CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Sweden Isoxaben 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is identical to the substance Isoxaben 407-190-8 82558-50-7 2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide Isoxaben C18H24N2O4 CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Sweden Isoxaben 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is identical to the substance Isoxaben 407-190-8 82558-50-7 2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide Isoxaben C18H24N2O4 CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Sweden Isoxaben 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is identical to the substance Isoxaben 407-190-8 82558-50-7 2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide Isoxaben C18H24N2O4 CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Sweden Isoxaben 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is identical to the substance Isoxaben 407-190-8 82558-50-7 2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide Isoxaben C18H24N2O4 CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Sweden Isoxaben 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is identical to the substance Isoxaben 407-190-8 82558-50-7 2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide Isoxaben C18H24N2O4 CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Sweden Isoxaben 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is identical to the substance Isoxaben 407-190-8 82558-50-7 2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide Isoxaben C18H24N2O4 CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Sweden Isoxaben 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is identical to the substance Isoxaben 407-190-8 82558-50-7 2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide Isoxaben C18H24N2O4 CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Sweden Isoxaben 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is identical to the substance Isoxaben 407-190-8 82558-50-7 2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide Isoxaben C18H24N2O4 CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Sweden Isoxaben 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is identical to the substance Isoxaben 407-190-8 82558-50-7 2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide Isoxaben C18H24N2O4 CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Sweden Isoxaben 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is identical to the substance Isoxaben 407-190-8 82558-50-7 2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide Isoxaben C18H24N2O4 CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Sweden Isoxaben 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is identical to the substance Isoxaben 407-190-8 82558-50-7 2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide Isoxaben C18H24N2O4 CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Sweden Isoxaben 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is identical to the substance Isoxaben 407-190-8 82558-50-7 2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide Isoxaben C18H24N2O4 CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Sweden Isoxaben 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is identical to the substance Isoxaben 407-190-8 82558-50-7 2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide Isoxaben C18H24N2O4 CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Sweden Isoxaben 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is identical to the substance Isoxaben 407-190-8 82558-50-7 2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide Isoxaben C18H24N2O4 CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: Sweden Isoxaben 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is identical to the substance Isoxaben 407-190-8 82558-50-7 2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide Isoxaben C18H24N2O4 CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: Sweden Isoxaben 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is identical to the substance Isoxaben 407-190-8 82558-50-7 2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide Isoxaben C18H24N2O4 CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes with Negative RMS: Sweden Isoxaben 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is identical to the substance Isoxaben 407-190-8 82558-50-7 2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide Isoxaben C18H24N2O4 CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes without Negative RMS: Sweden Isoxaben 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is identical to the substance Isoxaben 407-190-8 82558-50-7 2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide Isoxaben C18H24N2O4 CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes with Negative RMS: Sweden Isoxaben 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is identical to the substance Isoxaben 407-190-8 82558-50-7 2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide Isoxaben C18H24N2O4 CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes without Negative RMS: Sweden Isoxaben 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is identical to the substance Isoxaben 407-190-8 82558-50-7 2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide Isoxaben C18H24N2O4 CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data without Negative no information RMS: Sweden Isoxaben 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is identical to the substance Isoxaben 407-190-8 82558-50-7 2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide Isoxaben C18H24N2O4 CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data with Negative no information RMS: Sweden Isoxaben 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is identical to the substance Isoxaben 407-190-8 82558-50-7 2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide Isoxaben C18H24N2O4 CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vivo No guideline available Not reported Not applicable Acceptable Hamster (as animal) Not reported 9 Male oral: gavage 18.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Sweden Isoxaben 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is identical to the substance Isoxaben 407-190-8 82558-50-7 2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide Isoxaben C18H24N2O4 CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Swiss 10 Male oral: gavage 48.0000000000 h yes not applicable Positive no evidence RMS: Sweden Isoxaben 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is identical to the substance Isoxaben 407-190-8 82558-50-7 2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide Isoxaben C18H24N2O4 CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Swiss 10 Male oral: gavage 24.0000000000 h yes not applicable Positive no evidence RMS: Sweden Isoxaben 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is identical to the substance Isoxaben 407-190-8 82558-50-7 2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide Isoxaben C18H24N2O4 CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Swiss 10 Male oral: gavage 72.0000000000 h yes not applicable Negative no evidence RMS: Sweden Isoxaben 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is identical to the substance Isoxaben 407-190-8 82558-50-7 2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide Isoxaben C18H24N2O4 CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Swiss 5 Male oral: gavage 24.0000000000 h yes not applicable Positive no evidence RMS: Sweden Isoxaben 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is identical to the substance Isoxaben 407-190-8 82558-50-7 2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide Isoxaben C18H24N2O4 CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 48.0000000000 h yes not applicable Negative no evidence RMS: Sweden Isoxaben 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is identical to the substance Isoxaben 407-190-8 82558-50-7 2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide Isoxaben C18H24N2O4 CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 72.0000000000 h yes not applicable Negative no evidence RMS: Sweden Isoxaben 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is identical to the substance Isoxaben 407-190-8 82558-50-7 2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide Isoxaben C18H24N2O4 CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes not applicable Negative no evidence RMS: Sweden Isoxaben 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is identical to the substance Isoxaben 407-190-8 82558-50-7 2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide Isoxaben C18H24N2O4 CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) Yes Acceptable Rat (as animal) Wistar 25 Male oral: feed 19.0000000000 week yes not applicable Negative RMS: Sweden Isoxaben 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Iprovalicarb 604-209-3 single chemical entity Component is a metabolite of the substance (1RS)-1-(4-methylphenyl)ethanamine (1RS)-1-(4-methylphenyl)ethanamine Not in list C9H13N Cc1ccc(cc1)C(N)C InChI=1/C9H13N/c1-7-3-5-9(6-4-7)8(2)10/h3-6,8H,10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Ireland Iprovalicarb 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb 14Apr2015 2015 doi:10.2903/j.efsa.2015.4060
+Iprovalicarb 604-209-3 single chemical entity Component is a metabolite of the substance (1RS)-1-(4-methylphenyl)ethanamine (1RS)-1-(4-methylphenyl)ethanamine Not in list C9H13N Cc1ccc(cc1)C(N)C InChI=1/C9H13N/c1-7-3-5-9(6-4-7)8(2)10/h3-6,8H,10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Ireland Iprovalicarb 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb 14Apr2015 2015 doi:10.2903/j.efsa.2015.4060
+Iprovalicarb 604-209-3 single chemical entity Component is a metabolite of the substance (1RS)-1-(4-methylphenyl)ethanamine (1RS)-1-(4-methylphenyl)ethanamine Not in list C9H13N Cc1ccc(cc1)C(N)C InChI=1/C9H13N/c1-7-3-5-9(6-4-7)8(2)10/h3-6,8H,10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Ireland Iprovalicarb 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb 14Apr2015 2015 doi:10.2903/j.efsa.2015.4060
+Iprovalicarb 604-209-3 single chemical entity Component is a metabolite of the substance (1RS)-1-(4-methylphenyl)ethanamine (1RS)-1-(4-methylphenyl)ethanamine Not in list C9H13N Cc1ccc(cc1)C(N)C InChI=1/C9H13N/c1-7-3-5-9(6-4-7)8(2)10/h3-6,8H,10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Ireland Iprovalicarb 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb 14Apr2015 2015 doi:10.2903/j.efsa.2015.4060
+Iprovalicarb 604-209-3 single chemical entity Component is a metabolite of the substance (1RS)-1-(4-methylphenyl)ethanamine (1RS)-1-(4-methylphenyl)ethanamine Not in list C9H13N Cc1ccc(cc1)C(N)C InChI=1/C9H13N/c1-7-3-5-9(6-4-7)8(2)10/h3-6,8H,10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Ireland Iprovalicarb 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb 14Apr2015 2015 doi:10.2903/j.efsa.2015.4060
+Iprovalicarb 604-209-3 single chemical entity Component is a metabolite of the substance (1RS)-1-(4-methylphenyl)ethanamine (1RS)-1-(4-methylphenyl)ethanamine Not in list C9H13N Cc1ccc(cc1)C(N)C InChI=1/C9H13N/c1-7-3-5-9(6-4-7)8(2)10/h3-6,8H,10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Ireland Iprovalicarb 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb 14Apr2015 2015 doi:10.2903/j.efsa.2015.4060
+Iprovalicarb 604-209-3 single chemical entity Component is a metabolite of the substance (1RS)-1-(4-methylphenyl)ethanamine (1RS)-1-(4-methylphenyl)ethanamine Not in list C9H13N Cc1ccc(cc1)C(N)C InChI=1/C9H13N/c1-7-3-5-9(6-4-7)8(2)10/h3-6,8H,10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Ireland Iprovalicarb 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb 14Apr2015 2015 doi:10.2903/j.efsa.2015.4060
+Iprovalicarb 604-209-3 single chemical entity Component is a metabolite of the substance (1RS)-1-(4-methylphenyl)ethanamine (1RS)-1-(4-methylphenyl)ethanamine Not in list C9H13N Cc1ccc(cc1)C(N)C InChI=1/C9H13N/c1-7-3-5-9(6-4-7)8(2)10/h3-6,8H,10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Ireland Iprovalicarb 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb 14Apr2015 2015 doi:10.2903/j.efsa.2015.4060
+Iprovalicarb 604-209-3 single chemical entity Component is a metabolite of the substance (1RS)-1-(4-methylphenyl)ethanamine (1RS)-1-(4-methylphenyl)ethanamine Not in list C9H13N Cc1ccc(cc1)C(N)C InChI=1/C9H13N/c1-7-3-5-9(6-4-7)8(2)10/h3-6,8H,10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Ireland Iprovalicarb 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb 14Apr2015 2015 doi:10.2903/j.efsa.2015.4060
+Iprovalicarb 604-209-3 single chemical entity Component is a metabolite of the substance (1RS)-1-(4-methylphenyl)ethanamine (1RS)-1-(4-methylphenyl)ethanamine Not in list C9H13N Cc1ccc(cc1)C(N)C InChI=1/C9H13N/c1-7-3-5-9(6-4-7)8(2)10/h3-6,8H,10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Ireland Iprovalicarb 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb 14Apr2015 2015 doi:10.2903/j.efsa.2015.4060
+Imidacloprid 138261-41-3 single chemical entity Component is a metabolite of the substance 1-[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-5-ol dihydro-2-(nitroamino)-1H-imidazol-5-ol 1-[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-5-ol dihydro-2-(nitroamino)-1H-imidazol-5-ol Not in list C9H10ClN5O3 OC2C\N=C(\N[N+]([O-])=O)N2Cc1cnc(Cl)cc1 InChI=1/C9H10ClN5O3/c10-7-2-1-6(3-11-7)5-14-8(16)4-12-9(14)13-15(17)18/h1-3,8,16H,4-5H2,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is a metabolite of the substance 1-[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-5-ol dihydro-2-(nitroamino)-1H-imidazol-5-ol 1-[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-5-ol dihydro-2-(nitroamino)-1H-imidazol-5-ol Not in list C9H10ClN5O3 OC2C\N=C(\N[N+]([O-])=O)N2Cc1cnc(Cl)cc1 InChI=1/C9H10ClN5O3/c10-7-2-1-6(3-11-7)5-14-8(16)4-12-9(14)13-15(17)18/h1-3,8,16H,4-5H2,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is a metabolite of the substance 1-[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-5-ol dihydro-2-(nitroamino)-1H-imidazol-5-ol 1-[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-5-ol dihydro-2-(nitroamino)-1H-imidazol-5-ol Not in list C9H10ClN5O3 OC2C\N=C(\N[N+]([O-])=O)N2Cc1cnc(Cl)cc1 InChI=1/C9H10ClN5O3/c10-7-2-1-6(3-11-7)5-14-8(16)4-12-9(14)13-15(17)18/h1-3,8,16H,4-5H2,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is a metabolite of the substance 1-[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-5-ol dihydro-2-(nitroamino)-1H-imidazol-5-ol 1-[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-5-ol dihydro-2-(nitroamino)-1H-imidazol-5-ol Not in list C9H10ClN5O3 OC2C\N=C(\N[N+]([O-])=O)N2Cc1cnc(Cl)cc1 InChI=1/C9H10ClN5O3/c10-7-2-1-6(3-11-7)5-14-8(16)4-12-9(14)13-15(17)18/h1-3,8,16H,4-5H2,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is a metabolite of the substance 1-[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-5-ol dihydro-2-(nitroamino)-1H-imidazol-5-ol 1-[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-5-ol dihydro-2-(nitroamino)-1H-imidazol-5-ol Not in list C9H10ClN5O3 OC2C\N=C(\N[N+]([O-])=O)N2Cc1cnc(Cl)cc1 InChI=1/C9H10ClN5O3/c10-7-2-1-6(3-11-7)5-14-8(16)4-12-9(14)13-15(17)18/h1-3,8,16H,4-5H2,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is a metabolite of the substance 1-[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-5-ol dihydro-2-(nitroamino)-1H-imidazol-5-ol 1-[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-5-ol dihydro-2-(nitroamino)-1H-imidazol-5-ol Not in list C9H10ClN5O3 OC2C\N=C(\N[N+]([O-])=O)N2Cc1cnc(Cl)cc1 InChI=1/C9H10ClN5O3/c10-7-2-1-6(3-11-7)5-14-8(16)4-12-9(14)13-15(17)18/h1-3,8,16H,4-5H2,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is a metabolite of the substance 1-[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-5-ol dihydro-2-(nitroamino)-1H-imidazol-5-ol 1-[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-5-ol dihydro-2-(nitroamino)-1H-imidazol-5-ol Not in list C9H10ClN5O3 OC2C\N=C(\N[N+]([O-])=O)N2Cc1cnc(Cl)cc1 InChI=1/C9H10ClN5O3/c10-7-2-1-6(3-11-7)5-14-8(16)4-12-9(14)13-15(17)18/h1-3,8,16H,4-5H2,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is a metabolite of the substance 1-[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-5-ol dihydro-2-(nitroamino)-1H-imidazol-5-ol 1-[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-5-ol dihydro-2-(nitroamino)-1H-imidazol-5-ol Not in list C9H10ClN5O3 OC2C\N=C(\N[N+]([O-])=O)N2Cc1cnc(Cl)cc1 InChI=1/C9H10ClN5O3/c10-7-2-1-6(3-11-7)5-14-8(16)4-12-9(14)13-15(17)18/h1-3,8,16H,4-5H2,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is a metabolite of the substance 1-[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-5-ol dihydro-2-(nitroamino)-1H-imidazol-5-ol 1-[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-5-ol dihydro-2-(nitroamino)-1H-imidazol-5-ol Not in list C9H10ClN5O3 OC2C\N=C(\N[N+]([O-])=O)N2Cc1cnc(Cl)cc1 InChI=1/C9H10ClN5O3/c10-7-2-1-6(3-11-7)5-14-8(16)4-12-9(14)13-15(17)18/h1-3,8,16H,4-5H2,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is a metabolite of the substance 1-[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-5-ol dihydro-2-(nitroamino)-1H-imidazol-5-ol 1-[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-5-ol dihydro-2-(nitroamino)-1H-imidazol-5-ol Not in list C9H10ClN5O3 OC2C\N=C(\N[N+]([O-])=O)N2Cc1cnc(Cl)cc1 InChI=1/C9H10ClN5O3/c10-7-2-1-6(3-11-7)5-14-8(16)4-12-9(14)13-15(17)18/h1-3,8,16H,4-5H2,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is a metabolite of the substance 1[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-4-ol dihydro-2-(nitroamino)-1H-imidazol-4-ol 1[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-4-ol dihydro-2-(nitroamino)-1H-imidazol-4-ol Not in list C18H20Cl2N10O6 OC/2CN(Cc1cnc(Cl)cc1)C(\N[N+]([O-])=O)=N\2 InChI=1/C9H10ClN5O3/c10-7-2-1-6(3-11-7)4-14-5-8(16)12-9(14)13-15(17)18/h1-3,8,16H,4-5H2,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is a metabolite of the substance 1[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-4-ol dihydro-2-(nitroamino)-1H-imidazol-4-ol 1[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-4-ol dihydro-2-(nitroamino)-1H-imidazol-4-ol Not in list C18H20Cl2N10O6 OC/2CN(Cc1cnc(Cl)cc1)C(\N[N+]([O-])=O)=N\2 InChI=1/C9H10ClN5O3/c10-7-2-1-6(3-11-7)4-14-5-8(16)12-9(14)13-15(17)18/h1-3,8,16H,4-5H2,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is a metabolite of the substance 1[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-4-ol dihydro-2-(nitroamino)-1H-imidazol-4-ol 1[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-4-ol dihydro-2-(nitroamino)-1H-imidazol-4-ol Not in list C18H20Cl2N10O6 OC/2CN(Cc1cnc(Cl)cc1)C(\N[N+]([O-])=O)=N\2 InChI=1/C9H10ClN5O3/c10-7-2-1-6(3-11-7)4-14-5-8(16)12-9(14)13-15(17)18/h1-3,8,16H,4-5H2,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is a metabolite of the substance 1[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-4-ol dihydro-2-(nitroamino)-1H-imidazol-4-ol 1[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-4-ol dihydro-2-(nitroamino)-1H-imidazol-4-ol Not in list C18H20Cl2N10O6 OC/2CN(Cc1cnc(Cl)cc1)C(\N[N+]([O-])=O)=N\2 InChI=1/C9H10ClN5O3/c10-7-2-1-6(3-11-7)4-14-5-8(16)12-9(14)13-15(17)18/h1-3,8,16H,4-5H2,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is a metabolite of the substance 1[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-4-ol dihydro-2-(nitroamino)-1H-imidazol-4-ol 1[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-4-ol dihydro-2-(nitroamino)-1H-imidazol-4-ol Not in list C18H20Cl2N10O6 OC/2CN(Cc1cnc(Cl)cc1)C(\N[N+]([O-])=O)=N\2 InChI=1/C9H10ClN5O3/c10-7-2-1-6(3-11-7)4-14-5-8(16)12-9(14)13-15(17)18/h1-3,8,16H,4-5H2,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is a metabolite of the substance 1[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-4-ol dihydro-2-(nitroamino)-1H-imidazol-4-ol 1[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-4-ol dihydro-2-(nitroamino)-1H-imidazol-4-ol Not in list C18H20Cl2N10O6 OC/2CN(Cc1cnc(Cl)cc1)C(\N[N+]([O-])=O)=N\2 InChI=1/C9H10ClN5O3/c10-7-2-1-6(3-11-7)4-14-5-8(16)12-9(14)13-15(17)18/h1-3,8,16H,4-5H2,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is a metabolite of the substance 1[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-4-ol dihydro-2-(nitroamino)-1H-imidazol-4-ol 1[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-4-ol dihydro-2-(nitroamino)-1H-imidazol-4-ol Not in list C18H20Cl2N10O6 OC/2CN(Cc1cnc(Cl)cc1)C(\N[N+]([O-])=O)=N\2 InChI=1/C9H10ClN5O3/c10-7-2-1-6(3-11-7)4-14-5-8(16)12-9(14)13-15(17)18/h1-3,8,16H,4-5H2,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is a metabolite of the substance 1[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-4-ol dihydro-2-(nitroamino)-1H-imidazol-4-ol 1[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-4-ol dihydro-2-(nitroamino)-1H-imidazol-4-ol Not in list C18H20Cl2N10O6 OC/2CN(Cc1cnc(Cl)cc1)C(\N[N+]([O-])=O)=N\2 InChI=1/C9H10ClN5O3/c10-7-2-1-6(3-11-7)4-14-5-8(16)12-9(14)13-15(17)18/h1-3,8,16H,4-5H2,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is a metabolite of the substance 1[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-4-ol dihydro-2-(nitroamino)-1H-imidazol-4-ol 1[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-4-ol dihydro-2-(nitroamino)-1H-imidazol-4-ol Not in list C18H20Cl2N10O6 OC/2CN(Cc1cnc(Cl)cc1)C(\N[N+]([O-])=O)=N\2 InChI=1/C9H10ClN5O3/c10-7-2-1-6(3-11-7)4-14-5-8(16)12-9(14)13-15(17)18/h1-3,8,16H,4-5H2,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is a metabolite of the substance 1[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-4-ol dihydro-2-(nitroamino)-1H-imidazol-4-ol 1[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-4-ol dihydro-2-(nitroamino)-1H-imidazol-4-ol Not in list C18H20Cl2N10O6 OC/2CN(Cc1cnc(Cl)cc1)C(\N[N+]([O-])=O)=N\2 InChI=1/C9H10ClN5O3/c10-7-2-1-6(3-11-7)4-14-5-8(16)12-9(14)13-15(17)18/h1-3,8,16H,4-5H2,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is a metabolite of the substance 1-[(6-Chloro-3-pyridinyl)methyl]N-nitro-1H-imidazol-2-amine 1-[(6-Chloro-3-pyridinyl)methyl]N-nitro-1H-imidazol-2-amine Not in list C9H8ClN5O2 O=[N+]([O-])Nc2nccn2Cc1ccc(Cl)nc1 InChI=1/C9H8ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-5H,6H2,(H,11,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is a metabolite of the substance 1-[(6-Chloro-3-pyridinyl)methyl]N-nitro-1H-imidazol-2-amine 1-[(6-Chloro-3-pyridinyl)methyl]N-nitro-1H-imidazol-2-amine Not in list C9H8ClN5O2 O=[N+]([O-])Nc2nccn2Cc1ccc(Cl)nc1 InChI=1/C9H8ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-5H,6H2,(H,11,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is a metabolite of the substance 1-[(6-Chloro-3-pyridinyl)methyl]N-nitro-1H-imidazol-2-amine 1-[(6-Chloro-3-pyridinyl)methyl]N-nitro-1H-imidazol-2-amine Not in list C9H8ClN5O2 O=[N+]([O-])Nc2nccn2Cc1ccc(Cl)nc1 InChI=1/C9H8ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-5H,6H2,(H,11,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is a metabolite of the substance 1-[(6-Chloro-3-pyridinyl)methyl]N-nitro-1H-imidazol-2-amine 1-[(6-Chloro-3-pyridinyl)methyl]N-nitro-1H-imidazol-2-amine Not in list C9H8ClN5O2 O=[N+]([O-])Nc2nccn2Cc1ccc(Cl)nc1 InChI=1/C9H8ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-5H,6H2,(H,11,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is a metabolite of the substance 1-[(6-Chloro-3-pyridinyl)methyl]N-nitro-1H-imidazol-2-amine 1-[(6-Chloro-3-pyridinyl)methyl]N-nitro-1H-imidazol-2-amine Not in list C9H8ClN5O2 O=[N+]([O-])Nc2nccn2Cc1ccc(Cl)nc1 InChI=1/C9H8ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-5H,6H2,(H,11,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is a metabolite of the substance 1-[(6-Chloro-3-pyridinyl)methyl]N-nitro-1H-imidazol-2-amine 1-[(6-Chloro-3-pyridinyl)methyl]N-nitro-1H-imidazol-2-amine Not in list C9H8ClN5O2 O=[N+]([O-])Nc2nccn2Cc1ccc(Cl)nc1 InChI=1/C9H8ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-5H,6H2,(H,11,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is a metabolite of the substance 1-[(6-Chloro-3-pyridinyl)methyl]N-nitro-1H-imidazol-2-amine 1-[(6-Chloro-3-pyridinyl)methyl]N-nitro-1H-imidazol-2-amine Not in list C9H8ClN5O2 O=[N+]([O-])Nc2nccn2Cc1ccc(Cl)nc1 InChI=1/C9H8ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-5H,6H2,(H,11,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is a metabolite of the substance 1-[(6-Chloro-3-pyridinyl)methyl]N-nitro-1H-imidazol-2-amine 1-[(6-Chloro-3-pyridinyl)methyl]N-nitro-1H-imidazol-2-amine Not in list C9H8ClN5O2 O=[N+]([O-])Nc2nccn2Cc1ccc(Cl)nc1 InChI=1/C9H8ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-5H,6H2,(H,11,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is a metabolite of the substance 1-[(6-Chloro-3-pyridinyl)methyl]N-nitro-1H-imidazol-2-amine 1-[(6-Chloro-3-pyridinyl)methyl]N-nitro-1H-imidazol-2-amine Not in list C9H8ClN5O2 O=[N+]([O-])Nc2nccn2Cc1ccc(Cl)nc1 InChI=1/C9H8ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-5H,6H2,(H,11,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is a metabolite of the substance 1-[(6-Chloro-3-pyridinyl)methyl]N-nitro-1H-imidazol-2-amine 1-[(6-Chloro-3-pyridinyl)methyl]N-nitro-1H-imidazol-2-amine Not in list C9H8ClN5O2 O=[N+]([O-])Nc2nccn2Cc1ccc(Cl)nc1 InChI=1/C9H8ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-5H,6H2,(H,11,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is a metabolite of the substance 1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone 1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone Not in list C9H10ClN5O Clc2ncc(CN1CCN/C1=N\N=O)cc2 InChI=1/C9H10ClN5O/c10-8-2-1-7(5-12-8)6-15-4-3-11-9(15)13-14-16/h1-2,5H,3-4,6H2,(H,11,13,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is a metabolite of the substance 1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone 1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone Not in list C9H10ClN5O Clc2ncc(CN1CCN/C1=N\N=O)cc2 InChI=1/C9H10ClN5O/c10-8-2-1-7(5-12-8)6-15-4-3-11-9(15)13-14-16/h1-2,5H,3-4,6H2,(H,11,13,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is a metabolite of the substance 1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone 1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone Not in list C9H10ClN5O Clc2ncc(CN1CCN/C1=N\N=O)cc2 InChI=1/C9H10ClN5O/c10-8-2-1-7(5-12-8)6-15-4-3-11-9(15)13-14-16/h1-2,5H,3-4,6H2,(H,11,13,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is a metabolite of the substance 1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone 1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone Not in list C9H10ClN5O Clc2ncc(CN1CCN/C1=N\N=O)cc2 InChI=1/C9H10ClN5O/c10-8-2-1-7(5-12-8)6-15-4-3-11-9(15)13-14-16/h1-2,5H,3-4,6H2,(H,11,13,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is a metabolite of the substance 1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone 1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone Not in list C9H10ClN5O Clc2ncc(CN1CCN/C1=N\N=O)cc2 InChI=1/C9H10ClN5O/c10-8-2-1-7(5-12-8)6-15-4-3-11-9(15)13-14-16/h1-2,5H,3-4,6H2,(H,11,13,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is a metabolite of the substance 1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone 1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone Not in list C9H10ClN5O Clc2ncc(CN1CCN/C1=N\N=O)cc2 InChI=1/C9H10ClN5O/c10-8-2-1-7(5-12-8)6-15-4-3-11-9(15)13-14-16/h1-2,5H,3-4,6H2,(H,11,13,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is a metabolite of the substance 1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone 1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone Not in list C9H10ClN5O Clc2ncc(CN1CCN/C1=N\N=O)cc2 InChI=1/C9H10ClN5O/c10-8-2-1-7(5-12-8)6-15-4-3-11-9(15)13-14-16/h1-2,5H,3-4,6H2,(H,11,13,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is a metabolite of the substance 1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone 1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone Not in list C9H10ClN5O Clc2ncc(CN1CCN/C1=N\N=O)cc2 InChI=1/C9H10ClN5O/c10-8-2-1-7(5-12-8)6-15-4-3-11-9(15)13-14-16/h1-2,5H,3-4,6H2,(H,11,13,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is a metabolite of the substance 1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone 1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone Not in list C9H10ClN5O Clc2ncc(CN1CCN/C1=N\N=O)cc2 InChI=1/C9H10ClN5O/c10-8-2-1-7(5-12-8)6-15-4-3-11-9(15)13-14-16/h1-2,5H,3-4,6H2,(H,11,13,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is a metabolite of the substance 1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone 1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone Not in list C9H10ClN5O Clc2ncc(CN1CCN/C1=N\N=O)cc2 InChI=1/C9H10ClN5O/c10-8-2-1-7(5-12-8)6-15-4-3-11-9(15)13-14-16/h1-2,5H,3-4,6H2,(H,11,13,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is a metabolite of the substance 1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone 1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone Not in list C9H10ClN5O Clc2ncc(CN1CCN/C1=N\N=O)cc2 InChI=1/C9H10ClN5O/c10-8-2-1-7(5-12-8)6-15-4-3-11-9(15)13-14-16/h1-2,5H,3-4,6H2,(H,11,13,16) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is a metabolite of the substance 1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone 1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone Not in list C9H10ClN5O Clc2ncc(CN1CCN/C1=N\N=O)cc2 InChI=1/C9H10ClN5O/c10-8-2-1-7(5-12-8)6-15-4-3-11-9(15)13-14-16/h1-2,5H,3-4,6H2,(H,11,13,16) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is a metabolite of the substance 1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone 1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone Not in list C9H10ClN5O Clc2ncc(CN1CCN/C1=N\N=O)cc2 InChI=1/C9H10ClN5O/c10-8-2-1-7(5-12-8)6-15-4-3-11-9(15)13-14-16/h1-2,5H,3-4,6H2,(H,11,13,16) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is a metabolite of the substance 1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone 1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone Not in list C9H10ClN5O Clc2ncc(CN1CCN/C1=N\N=O)cc2 InChI=1/C9H10ClN5O/c10-8-2-1-7(5-12-8)6-15-4-3-11-9(15)13-14-16/h1-2,5H,3-4,6H2,(H,11,13,16) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is a metabolite of the substance 1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone 1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone Not in list C9H10ClN5O Clc2ncc(CN1CCN/C1=N\N=O)cc2 InChI=1/C9H10ClN5O/c10-8-2-1-7(5-12-8)6-15-4-3-11-9(15)13-14-16/h1-2,5H,3-4,6H2,(H,11,13,16) organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes, concurrent vehicle without Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is a metabolite of the substance 1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone 1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone Not in list C9H10ClN5O Clc2ncc(CN1CCN/C1=N\N=O)cc2 InChI=1/C9H10ClN5O/c10-8-2-1-7(5-12-8)6-15-4-3-11-9(15)13-14-16/h1-2,5H,3-4,6H2,(H,11,13,16) organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes, concurrent vehicle with Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is a metabolite of the substance 1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone 1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone Not in list C9H10ClN5O Clc2ncc(CN1CCN/C1=N\N=O)cc2 InChI=1/C9H10ClN5O/c10-8-2-1-7(5-12-8)6-15-4-3-11-9(15)13-14-16/h1-2,5H,3-4,6H2,(H,11,13,16) organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes, concurrent vehicle without Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is a metabolite of the substance 1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone 1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone Not in list C9H10ClN5O Clc2ncc(CN1CCN/C1=N\N=O)cc2 InChI=1/C9H10ClN5O/c10-8-2-1-7(5-12-8)6-15-4-3-11-9(15)13-14-16/h1-2,5H,3-4,6H2,(H,11,13,16) organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes, concurrent vehicle with Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is a metabolite of the substance 1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone 1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone Not in list C9H10ClN5O Clc2ncc(CN1CCN/C1=N\N=O)cc2 InChI=1/C9H10ClN5O/c10-8-2-1-7(5-12-8)6-15-4-3-11-9(15)13-14-16/h1-2,5H,3-4,6H2,(H,11,13,16) organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is a metabolite of the substance 1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone 1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone Not in list C9H10ClN5O Clc2ncc(CN1CCN/C1=N\N=O)cc2 InChI=1/C9H10ClN5O/c10-8-2-1-7(5-12-8)6-15-4-3-11-9(15)13-14-16/h1-2,5H,3-4,6H2,(H,11,13,16) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is a metabolite of the substance 1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone 1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone Not in list C9H10ClN5O Clc2ncc(CN1CCN/C1=N\N=O)cc2 InChI=1/C9H10ClN5O/c10-8-2-1-7(5-12-8)6-15-4-3-11-9(15)13-14-16/h1-2,5H,3-4,6H2,(H,11,13,16) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is a metabolite of the substance 1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone 1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone Not in list C9H10ClN5O Clc2ncc(CN1CCN/C1=N\N=O)cc2 InChI=1/C9H10ClN5O/c10-8-2-1-7(5-12-8)6-15-4-3-11-9(15)13-14-16/h1-2,5H,3-4,6H2,(H,11,13,16) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) BDF1 mouse Male oral: gavage no data not applicable Inconclusive no evidence RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is a metabolite of the substance 1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone 1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone Not in list C9H10ClN5O Clc2ncc(CN1CCN/C1=N\N=O)cc2 InChI=1/C9H10ClN5O/c10-8-2-1-7(5-12-8)6-15-4-3-11-9(15)13-14-16/h1-2,5H,3-4,6H2,(H,11,13,16) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI No data oral: unspecified 24.0000000000 h no data not applicable Negative no evidence RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is a metabolite of the substance 1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone 1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone Not in list C9H10ClN5O Clc2ncc(CN1CCN/C1=N\N=O)cc2 InChI=1/C9H10ClN5O/c10-8-2-1-7(5-12-8)6-15-4-3-11-9(15)13-14-16/h1-2,5H,3-4,6H2,(H,11,13,16) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI No data oral: unspecified 72.0000000000 h no data not applicable Negative no evidence RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is a metabolite of the substance 1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone 1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone Not in list C9H10ClN5O Clc2ncc(CN1CCN/C1=N\N=O)cc2 InChI=1/C9H10ClN5O/c10-8-2-1-7(5-12-8)6-15-4-3-11-9(15)13-14-16/h1-2,5H,3-4,6H2,(H,11,13,16) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI No data oral: unspecified 48.0000000000 h no data not applicable Negative no evidence RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is a metabolite of the substance 1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone 1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone Not in list C9H10ClN5O Clc2ncc(CN1CCN/C1=N\N=O)cc2 InChI=1/C9H10ClN5O/c10-8-2-1-7(5-12-8)6-15-4-3-11-9(15)13-14-16/h1-2,5H,3-4,6H2,(H,11,13,16) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) BDF1 mouse Male intraperitoneal no data not applicable Inconclusive no evidence RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is a metabolite of the substance 1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone 1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone Not in list C9H10ClN5O Clc2ncc(CN1CCN/C1=N\N=O)cc2 InChI=1/C9H10ClN5O/c10-8-2-1-7(5-12-8)6-15-4-3-11-9(15)13-14-16/h1-2,5H,3-4,6H2,(H,11,13,16) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI No data intraperitoneal 72.0000000000 h no data not applicable Negative no evidence RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is a metabolite of the substance 1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone 1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone Not in list C9H10ClN5O Clc2ncc(CN1CCN/C1=N\N=O)cc2 InChI=1/C9H10ClN5O/c10-8-2-1-7(5-12-8)6-15-4-3-11-9(15)13-14-16/h1-2,5H,3-4,6H2,(H,11,13,16) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI No data intraperitoneal 48.0000000000 h no data not applicable Negative no evidence RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Imidacloprid 138261-41-3 single chemical entity Component is a metabolite of the substance 1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone 1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone Not in list C9H10ClN5O Clc2ncc(CN1CCN/C1=N\N=O)cc2 InChI=1/C9H10ClN5O/c10-8-2-1-7(5-12-8)6-15-4-3-11-9(15)13-14-16/h1-2,5H,3-4,6H2,(H,11,13,16) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI No data intraperitoneal 24.0000000000 h no data not applicable Negative no evidence RMS: Germany Imidacloprid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid 28Jul2008 2008 doi:10.2903/j.efsa.2008.148r
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is a metabolite of the substance N-{3-[(2RS)-2-hydroxybutan-2-yl]-1,2-oxazol-5-yl} -2,6-dimethoxybenzamide N-(3-ethylisoxazol-5-yl)-2,6-dimethoxybenzamide Not in list C15H20N2O5 CCc2cc(NC(=O)c1c(OC)cccc1OC)on2 InChI=1/C14H16N2O4/c1-4-9-8-12(20-16-9)15-14(17)13-10(18-2)6-5-7-11(13)19-3/h5-8H,4H2,1-3H3,(H,15,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Sweden Isoxaben 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is a metabolite of the substance N-{3-[(2RS)-2-hydroxybutan-2-yl]-1,2-oxazol-5-yl} -2,6-dimethoxybenzamide N-(3-ethylisoxazol-5-yl)-2,6-dimethoxybenzamide Not in list C15H20N2O5 CCc2cc(NC(=O)c1c(OC)cccc1OC)on2 InChI=1/C14H16N2O4/c1-4-9-8-12(20-16-9)15-14(17)13-10(18-2)6-5-7-11(13)19-3/h5-8H,4H2,1-3H3,(H,15,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Sweden Isoxaben 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is a metabolite of the substance N-{3-[(2RS)-2-hydroxybutan-2-yl]-1,2-oxazol-5-yl} -2,6-dimethoxybenzamide N-(3-ethylisoxazol-5-yl)-2,6-dimethoxybenzamide Not in list C15H20N2O5 CCc2cc(NC(=O)c1c(OC)cccc1OC)on2 InChI=1/C14H16N2O4/c1-4-9-8-12(20-16-9)15-14(17)13-10(18-2)6-5-7-11(13)19-3/h5-8H,4H2,1-3H3,(H,15,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Sweden Isoxaben 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is a metabolite of the substance N-{3-[(2RS)-2-hydroxybutan-2-yl]-1,2-oxazol-5-yl} -2,6-dimethoxybenzamide N-(3-ethylisoxazol-5-yl)-2,6-dimethoxybenzamide Not in list C15H20N2O5 CCc2cc(NC(=O)c1c(OC)cccc1OC)on2 InChI=1/C14H16N2O4/c1-4-9-8-12(20-16-9)15-14(17)13-10(18-2)6-5-7-11(13)19-3/h5-8H,4H2,1-3H3,(H,15,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Sweden Isoxaben 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is a metabolite of the substance N-{3-[(2RS)-2-hydroxybutan-2-yl]-1,2-oxazol-5-yl} -2,6-dimethoxybenzamide N-(3-ethylisoxazol-5-yl)-2,6-dimethoxybenzamide Not in list C15H20N2O5 CCc2cc(NC(=O)c1c(OC)cccc1OC)on2 InChI=1/C14H16N2O4/c1-4-9-8-12(20-16-9)15-14(17)13-10(18-2)6-5-7-11(13)19-3/h5-8H,4H2,1-3H3,(H,15,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Sweden Isoxaben 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is a metabolite of the substance N-{3-[(2RS)-2-hydroxybutan-2-yl]-1,2-oxazol-5-yl} -2,6-dimethoxybenzamide N-(3-ethylisoxazol-5-yl)-2,6-dimethoxybenzamide Not in list C15H20N2O5 CCc2cc(NC(=O)c1c(OC)cccc1OC)on2 InChI=1/C14H16N2O4/c1-4-9-8-12(20-16-9)15-14(17)13-10(18-2)6-5-7-11(13)19-3/h5-8H,4H2,1-3H3,(H,15,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Sweden Isoxaben 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is a metabolite of the substance N-{3-[(2RS)-2-hydroxybutan-2-yl]-1,2-oxazol-5-yl} -2,6-dimethoxybenzamide N-(3-ethylisoxazol-5-yl)-2,6-dimethoxybenzamide Not in list C15H20N2O5 CCc2cc(NC(=O)c1c(OC)cccc1OC)on2 InChI=1/C14H16N2O4/c1-4-9-8-12(20-16-9)15-14(17)13-10(18-2)6-5-7-11(13)19-3/h5-8H,4H2,1-3H3,(H,15,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Sweden Isoxaben 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is a metabolite of the substance N-{3-[(2RS)-2-hydroxybutan-2-yl]-1,2-oxazol-5-yl} -2,6-dimethoxybenzamide N-(3-ethylisoxazol-5-yl)-2,6-dimethoxybenzamide Not in list C15H20N2O5 CCc2cc(NC(=O)c1c(OC)cccc1OC)on2 InChI=1/C14H16N2O4/c1-4-9-8-12(20-16-9)15-14(17)13-10(18-2)6-5-7-11(13)19-3/h5-8H,4H2,1-3H3,(H,15,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Sweden Isoxaben 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is a metabolite of the substance N-{3-[(2RS)-2-hydroxybutan-2-yl]-1,2-oxazol-5-yl} -2,6-dimethoxybenzamide N-(3-ethylisoxazol-5-yl)-2,6-dimethoxybenzamide Not in list C15H20N2O5 CCc2cc(NC(=O)c1c(OC)cccc1OC)on2 InChI=1/C14H16N2O4/c1-4-9-8-12(20-16-9)15-14(17)13-10(18-2)6-5-7-11(13)19-3/h5-8H,4H2,1-3H3,(H,15,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Sweden Isoxaben 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is a metabolite of the substance N-{3-[(2RS)-2-hydroxybutan-2-yl]-1,2-oxazol-5-yl} -2,6-dimethoxybenzamide N-(3-ethylisoxazol-5-yl)-2,6-dimethoxybenzamide Not in list C15H20N2O5 CCc2cc(NC(=O)c1c(OC)cccc1OC)on2 InChI=1/C14H16N2O4/c1-4-9-8-12(20-16-9)15-14(17)13-10(18-2)6-5-7-11(13)19-3/h5-8H,4H2,1-3H3,(H,15,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Sweden Isoxaben 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is a metabolite of the substance N-{3-[(2RS)-2-hydroxybutan-2-yl]-1,2-oxazol-5-yl} -2,6-dimethoxybenzamide N-(3-ethylisoxazol-5-yl)-2,6-dimethoxybenzamide Not in list C15H20N2O5 CCc2cc(NC(=O)c1c(OC)cccc1OC)on2 InChI=1/C14H16N2O4/c1-4-9-8-12(20-16-9)15-14(17)13-10(18-2)6-5-7-11(13)19-3/h5-8H,4H2,1-3H3,(H,15,17) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: Sweden Isoxaben 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is a metabolite of the substance N-{3-[(2RS)-2-hydroxybutan-2-yl]-1,2-oxazol-5-yl} -2,6-dimethoxybenzamide N-(3-ethylisoxazol-5-yl)-2,6-dimethoxybenzamide Not in list C15H20N2O5 CCc2cc(NC(=O)c1c(OC)cccc1OC)on2 InChI=1/C14H16N2O4/c1-4-9-8-12(20-16-9)15-14(17)13-10(18-2)6-5-7-11(13)19-3/h5-8H,4H2,1-3H3,(H,15,17) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: Sweden Isoxaben 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is a metabolite of the substance N-{3-[(2RS)-2-hydroxybutan-2-yl]-1,2-oxazol-5-yl} -2,6-dimethoxybenzamide N-(3-ethylisoxazol-5-yl)-2,6-dimethoxybenzamide Not in list C15H20N2O5 CCc2cc(NC(=O)c1c(OC)cccc1OC)on2 InChI=1/C14H16N2O4/c1-4-9-8-12(20-16-9)15-14(17)13-10(18-2)6-5-7-11(13)19-3/h5-8H,4H2,1-3H3,(H,15,17) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative small colonies RMS: Sweden Isoxaben 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is a metabolite of the substance N-{3-[(2RS)-2-hydroxybutan-2-yl]-1,2-oxazol-5-yl} -2,6-dimethoxybenzamide N-(3-ethylisoxazol-5-yl)-2,6-dimethoxybenzamide Not in list C15H20N2O5 CCc2cc(NC(=O)c1c(OC)cccc1OC)on2 InChI=1/C14H16N2O4/c1-4-9-8-12(20-16-9)15-14(17)13-10(18-2)6-5-7-11(13)19-3/h5-8H,4H2,1-3H3,(H,15,17) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative small colonies RMS: Sweden Isoxaben 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is a metabolite of the substance N-{3-[(2RS)-2-hydroxybutan-2-yl]-1,2-oxazol-5-yl} -2,6-dimethoxybenzamide N-(3-ethylisoxazol-5-yl)-2,6-dimethoxybenzamide Not in list C15H20N2O5 CCc2cc(NC(=O)c1c(OC)cccc1OC)on2 InChI=1/C14H16N2O4/c1-4-9-8-12(20-16-9)15-14(17)13-10(18-2)6-5-7-11(13)19-3/h5-8H,4H2,1-3H3,(H,15,17) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative large colonies RMS: Sweden Isoxaben 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is a metabolite of the substance N-{3-[(2RS)-2-hydroxybutan-2-yl]-1,2-oxazol-5-yl} -2,6-dimethoxybenzamide N-(3-ethylisoxazol-5-yl)-2,6-dimethoxybenzamide Not in list C15H20N2O5 CCc2cc(NC(=O)c1c(OC)cccc1OC)on2 InChI=1/C14H16N2O4/c1-4-9-8-12(20-16-9)15-14(17)13-10(18-2)6-5-7-11(13)19-3/h5-8H,4H2,1-3H3,(H,15,17) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative large colonies RMS: Sweden Isoxaben 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is a metabolite of the substance 2,6-dimethoxybenzamide 2,6-dimethoxybenzamide Not in list C9H11NO3 COc1cccc(OC)c1C(N)=O InChI=1/C9H11NO3/c1-12-6-4-3-5-7(13-2)8(6)9(10)11/h3-5H,1-2H3,(H2,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Sweden Isoxaben (Addendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is a metabolite of the substance 2,6-dimethoxybenzamide 2,6-dimethoxybenzamide Not in list C9H11NO3 COc1cccc(OC)c1C(N)=O InChI=1/C9H11NO3/c1-12-6-4-3-5-7(13-2)8(6)9(10)11/h3-5H,1-2H3,(H2,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Sweden Isoxaben (Addendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is a metabolite of the substance 2,6-dimethoxybenzamide 2,6-dimethoxybenzamide Not in list C9H11NO3 COc1cccc(OC)c1C(N)=O InChI=1/C9H11NO3/c1-12-6-4-3-5-7(13-2)8(6)9(10)11/h3-5H,1-2H3,(H2,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Sweden Isoxaben (Addendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is a metabolite of the substance 2,6-dimethoxybenzamide 2,6-dimethoxybenzamide Not in list C9H11NO3 COc1cccc(OC)c1C(N)=O InChI=1/C9H11NO3/c1-12-6-4-3-5-7(13-2)8(6)9(10)11/h3-5H,1-2H3,(H2,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Sweden Isoxaben (Addendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is a metabolite of the substance 2,6-dimethoxybenzamide 2,6-dimethoxybenzamide Not in list C9H11NO3 COc1cccc(OC)c1C(N)=O InChI=1/C9H11NO3/c1-12-6-4-3-5-7(13-2)8(6)9(10)11/h3-5H,1-2H3,(H2,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Sweden Isoxaben (Addendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is a metabolite of the substance 2,6-dimethoxybenzamide 2,6-dimethoxybenzamide Not in list C9H11NO3 COc1cccc(OC)c1C(N)=O InChI=1/C9H11NO3/c1-12-6-4-3-5-7(13-2)8(6)9(10)11/h3-5H,1-2H3,(H2,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Sweden Isoxaben (Addendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is a metabolite of the substance 2,6-dimethoxybenzamide 2,6-dimethoxybenzamide Not in list C9H11NO3 COc1cccc(OC)c1C(N)=O InChI=1/C9H11NO3/c1-12-6-4-3-5-7(13-2)8(6)9(10)11/h3-5H,1-2H3,(H2,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Sweden Isoxaben (Addendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is a metabolite of the substance 2,6-dimethoxybenzamide 2,6-dimethoxybenzamide Not in list C9H11NO3 COc1cccc(OC)c1C(N)=O InChI=1/C9H11NO3/c1-12-6-4-3-5-7(13-2)8(6)9(10)11/h3-5H,1-2H3,(H2,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Sweden Isoxaben (Addendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is a metabolite of the substance 2,6-dimethoxybenzamide 2,6-dimethoxybenzamide Not in list C9H11NO3 COc1cccc(OC)c1C(N)=O InChI=1/C9H11NO3/c1-12-6-4-3-5-7(13-2)8(6)9(10)11/h3-5H,1-2H3,(H2,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Sweden Isoxaben (Addendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is a metabolite of the substance 2,6-dimethoxybenzamide 2,6-dimethoxybenzamide Not in list C9H11NO3 COc1cccc(OC)c1C(N)=O InChI=1/C9H11NO3/c1-12-6-4-3-5-7(13-2)8(6)9(10)11/h3-5H,1-2H3,(H2,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Sweden Isoxaben (Addendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is a metabolite of the substance 2,6-dimethoxybenzamide 2,6-dimethoxybenzamide Not in list C9H11NO3 COc1cccc(OC)c1C(N)=O InChI=1/C9H11NO3/c1-12-6-4-3-5-7(13-2)8(6)9(10)11/h3-5H,1-2H3,(H2,10,11) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Rat (as animal) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Sweden Isoxaben (Addendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is a metabolite of the substance 2,6-dimethoxybenzamide 2,6-dimethoxybenzamide Not in list C9H11NO3 COc1cccc(OC)c1C(N)=O InChI=1/C9H11NO3/c1-12-6-4-3-5-7(13-2)8(6)9(10)11/h3-5H,1-2H3,(H2,10,11) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Rat (as animal) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Sweden Isoxaben (Addendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is identical to the substance Isoxaben 407-190-8 82558-50-7 2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide Isoxaben C18H24N2O4 CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Sweden Isoxaben (Addendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Isoxaben 407-190-8 82558-50-7 single chemical entity Component is identical to the substance Isoxaben 407-190-8 82558-50-7 2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide Isoxaben C18H24N2O4 CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Sweden Isoxaben (Addendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben 03Sep2010 2010 doi:10.2903/j.efsa.2010.1714
+Lenacil 218-499-0 2164-08-1 single chemical entity Component is identical to the substance Lenacil 218-499-0 2164-08-1 3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione Lenacil C13H18N2O2 O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3 InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Belgium Lenacil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil 07Oct2009 2009 doi:10.2903/j.efsa.2009.1326
+Lenacil 218-499-0 2164-08-1 single chemical entity Component is identical to the substance Lenacil 218-499-0 2164-08-1 3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione Lenacil C13H18N2O2 O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3 InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Belgium Lenacil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil 07Oct2009 2009 doi:10.2903/j.efsa.2009.1326
+Lenacil 218-499-0 2164-08-1 single chemical entity Component is identical to the substance Lenacil 218-499-0 2164-08-1 3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione Lenacil C13H18N2O2 O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3 InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Belgium Lenacil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil 07Oct2009 2009 doi:10.2903/j.efsa.2009.1326
+Lenacil 218-499-0 2164-08-1 single chemical entity Component is identical to the substance Lenacil 218-499-0 2164-08-1 3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione Lenacil C13H18N2O2 O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3 InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Belgium Lenacil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil 07Oct2009 2009 doi:10.2903/j.efsa.2009.1326
+Lenacil 218-499-0 2164-08-1 single chemical entity Component is identical to the substance Lenacil 218-499-0 2164-08-1 3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione Lenacil C13H18N2O2 O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3 InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Belgium Lenacil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil 07Oct2009 2009 doi:10.2903/j.efsa.2009.1326
+Lenacil 218-499-0 2164-08-1 single chemical entity Component is identical to the substance Lenacil 218-499-0 2164-08-1 3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione Lenacil C13H18N2O2 O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3 InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Belgium Lenacil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil 07Oct2009 2009 doi:10.2903/j.efsa.2009.1326
+Lenacil 218-499-0 2164-08-1 single chemical entity Component is identical to the substance Lenacil 218-499-0 2164-08-1 3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione Lenacil C13H18N2O2 O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3 InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes with Negative RMS: Belgium Lenacil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil 07Oct2009 2009 doi:10.2903/j.efsa.2009.1326
+Lenacil 218-499-0 2164-08-1 single chemical entity Component is identical to the substance Lenacil 218-499-0 2164-08-1 3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione Lenacil C13H18N2O2 O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3 InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Belgium Lenacil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil 07Oct2009 2009 doi:10.2903/j.efsa.2009.1326
+Lenacil 218-499-0 2164-08-1 single chemical entity Component is identical to the substance Lenacil 218-499-0 2164-08-1 3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione Lenacil C13H18N2O2 O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3 InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes without Negative RMS: Belgium Lenacil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil 07Oct2009 2009 doi:10.2903/j.efsa.2009.1326
+Lenacil 218-499-0 2164-08-1 single chemical entity Component is identical to the substance Lenacil 218-499-0 2164-08-1 3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione Lenacil C13H18N2O2 O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3 InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Belgium Lenacil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil 07Oct2009 2009 doi:10.2903/j.efsa.2009.1326
+Lenacil 218-499-0 2164-08-1 single chemical entity Component is identical to the substance Lenacil 218-499-0 2164-08-1 3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione Lenacil C13H18N2O2 O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3 InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle with Negative RMS: Belgium Lenacil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil 07Oct2009 2009 doi:10.2903/j.efsa.2009.1326
+Lenacil 218-499-0 2164-08-1 single chemical entity Component is identical to the substance Lenacil 218-499-0 2164-08-1 3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione Lenacil C13H18N2O2 O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3 InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium Lenacil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil 07Oct2009 2009 doi:10.2903/j.efsa.2009.1326
+Lenacil 218-499-0 2164-08-1 single chemical entity Component is identical to the substance Lenacil 218-499-0 2164-08-1 3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione Lenacil C13H18N2O2 O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3 InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium Lenacil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil 07Oct2009 2009 doi:10.2903/j.efsa.2009.1326
+Lenacil 218-499-0 2164-08-1 single chemical entity Component is identical to the substance Lenacil 218-499-0 2164-08-1 3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione Lenacil C13H18N2O2 O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3 InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium Lenacil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil 07Oct2009 2009 doi:10.2903/j.efsa.2009.1326
+Lenacil 218-499-0 2164-08-1 single chemical entity Component is identical to the substance Lenacil 218-499-0 2164-08-1 3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione Lenacil C13H18N2O2 O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3 InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium Lenacil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil 07Oct2009 2009 doi:10.2903/j.efsa.2009.1326
+Lenacil 218-499-0 2164-08-1 single chemical entity Component is identical to the substance Lenacil 218-499-0 2164-08-1 3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione Lenacil C13H18N2O2 O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3 InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle without Negative RMS: Belgium Lenacil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil 07Oct2009 2009 doi:10.2903/j.efsa.2009.1326
+Lenacil 218-499-0 2164-08-1 single chemical entity Component is identical to the substance Lenacil 218-499-0 2164-08-1 3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione Lenacil C13H18N2O2 O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3 InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium Lenacil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil 07Oct2009 2009 doi:10.2903/j.efsa.2009.1326
+Lenacil 218-499-0 2164-08-1 single chemical entity Component is identical to the substance Lenacil 218-499-0 2164-08-1 3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione Lenacil C13H18N2O2 O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3 InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium Lenacil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil 07Oct2009 2009 doi:10.2903/j.efsa.2009.1326
+Lenacil 218-499-0 2164-08-1 single chemical entity Component is identical to the substance Lenacil 218-499-0 2164-08-1 3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione Lenacil C13H18N2O2 O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3 InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: Belgium Lenacil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil 07Oct2009 2009 doi:10.2903/j.efsa.2009.1326
+Lenacil 218-499-0 2164-08-1 single chemical entity Component is identical to the substance Lenacil 218-499-0 2164-08-1 3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione Lenacil C13H18N2O2 O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3 InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Belgium Lenacil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil 07Oct2009 2009 doi:10.2903/j.efsa.2009.1326
+Lenacil 218-499-0 2164-08-1 single chemical entity Component is identical to the substance Lenacil 218-499-0 2164-08-1 3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione Lenacil C13H18N2O2 O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3 InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: Belgium Lenacil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil 07Oct2009 2009 doi:10.2903/j.efsa.2009.1326
+Lenacil 218-499-0 2164-08-1 single chemical entity Component is identical to the substance Lenacil 218-499-0 2164-08-1 3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione Lenacil C13H18N2O2 O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3 InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Belgium Lenacil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil 07Oct2009 2009 doi:10.2903/j.efsa.2009.1326
+Lenacil 218-499-0 2164-08-1 single chemical entity Component is identical to the substance Lenacil 218-499-0 2164-08-1 3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione Lenacil C13H18N2O2 O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3 InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Belgium Lenacil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil 07Oct2009 2009 doi:10.2903/j.efsa.2009.1326
+Lenacil 218-499-0 2164-08-1 single chemical entity Component is identical to the substance Lenacil 218-499-0 2164-08-1 3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione Lenacil C13H18N2O2 O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3 InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Belgium Lenacil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil 07Oct2009 2009 doi:10.2903/j.efsa.2009.1326
+Lenacil 218-499-0 2164-08-1 single chemical entity Component is identical to the substance Lenacil 218-499-0 2164-08-1 3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione Lenacil C13H18N2O2 O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3 InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Belgium Lenacil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil 07Oct2009 2009 doi:10.2903/j.efsa.2009.1326
+Lenacil 218-499-0 2164-08-1 single chemical entity Component is identical to the substance Lenacil 218-499-0 2164-08-1 3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione Lenacil C13H18N2O2 O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3 InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Belgium Lenacil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil 07Oct2009 2009 doi:10.2903/j.efsa.2009.1326
+Lenacil 218-499-0 2164-08-1 single chemical entity Component is identical to the substance Lenacil 218-499-0 2164-08-1 3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione Lenacil C13H18N2O2 O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3 InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Belgium Lenacil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil 07Oct2009 2009 doi:10.2903/j.efsa.2009.1326
+Lenacil 218-499-0 2164-08-1 single chemical entity Component is identical to the substance Lenacil 218-499-0 2164-08-1 3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione Lenacil C13H18N2O2 O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3 InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Belgium Lenacil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil 07Oct2009 2009 doi:10.2903/j.efsa.2009.1326
+Lenacil 218-499-0 2164-08-1 single chemical entity Component is identical to the substance Lenacil 218-499-0 2164-08-1 3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione Lenacil C13H18N2O2 O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3 InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported no data without Negative RMS: Belgium Lenacil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil 07Oct2009 2009 doi:10.2903/j.efsa.2009.1326
+Lenacil 218-499-0 2164-08-1 single chemical entity Component is identical to the substance Lenacil 218-499-0 2164-08-1 3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione Lenacil C13H18N2O2 O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3 InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Belgium Lenacil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil 07Oct2009 2009 doi:10.2903/j.efsa.2009.1326
+Lenacil 218-499-0 2164-08-1 single chemical entity Component is identical to the substance Lenacil 218-499-0 2164-08-1 3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione Lenacil C13H18N2O2 O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3 InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Belgium Lenacil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil 07Oct2009 2009 doi:10.2903/j.efsa.2009.1326
+Lenacil 218-499-0 2164-08-1 single chemical entity Component is identical to the substance Lenacil 218-499-0 2164-08-1 3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione Lenacil C13H18N2O2 O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3 InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Belgium Lenacil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil 07Oct2009 2009 doi:10.2903/j.efsa.2009.1326
+Lenacil 218-499-0 2164-08-1 single chemical entity Component is identical to the substance Lenacil 218-499-0 2164-08-1 3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione Lenacil C13H18N2O2 O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3 InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Belgium Lenacil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil 07Oct2009 2009 doi:10.2903/j.efsa.2009.1326
+Lenacil 218-499-0 2164-08-1 single chemical entity Component is identical to the substance Lenacil 218-499-0 2164-08-1 3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione Lenacil C13H18N2O2 O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3 InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Belgium Lenacil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil 07Oct2009 2009 doi:10.2903/j.efsa.2009.1326
+Lenacil 218-499-0 2164-08-1 single chemical entity Component is identical to the substance Lenacil 218-499-0 2164-08-1 3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione Lenacil C13H18N2O2 O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3 InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported no data with Negative RMS: Belgium Lenacil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil 07Oct2009 2009 doi:10.2903/j.efsa.2009.1326
+Lenacil 218-499-0 2164-08-1 single chemical entity Component is identical to the substance Lenacil 218-499-0 2164-08-1 3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione Lenacil C13H18N2O2 O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3 InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Belgium Lenacil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil 07Oct2009 2009 doi:10.2903/j.efsa.2009.1326
+Lenacil 218-499-0 2164-08-1 single chemical entity Component is identical to the substance Lenacil 218-499-0 2164-08-1 3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione Lenacil C13H18N2O2 O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3 InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data without Negative no information RMS: Belgium Lenacil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil 07Oct2009 2009 doi:10.2903/j.efsa.2009.1326
+Lenacil 218-499-0 2164-08-1 single chemical entity Component is identical to the substance Lenacil 218-499-0 2164-08-1 3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione Lenacil C13H18N2O2 O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3 InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data with Negative no information RMS: Belgium Lenacil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil 07Oct2009 2009 doi:10.2903/j.efsa.2009.1326
+Lenacil 218-499-0 2164-08-1 single chemical entity Component is identical to the substance Lenacil 218-499-0 2164-08-1 3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione Lenacil C13H18N2O2 O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3 InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Belgium Lenacil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil 07Oct2009 2009 doi:10.2903/j.efsa.2009.1326
+Lenacil 218-499-0 2164-08-1 single chemical entity Component is identical to the substance Lenacil 218-499-0 2164-08-1 3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione Lenacil C13H18N2O2 O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3 InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Positive RMS: Belgium Lenacil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil 07Oct2009 2009 doi:10.2903/j.efsa.2009.1326
+Lenacil 218-499-0 2164-08-1 single chemical entity Component is identical to the substance Lenacil 218-499-0 2164-08-1 3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione Lenacil C13H18N2O2 O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3 InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17) organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Belgium Lenacil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil 07Oct2009 2009 doi:10.2903/j.efsa.2009.1326
+Lenacil 218-499-0 2164-08-1 single chemical entity Component is identical to the substance Lenacil 218-499-0 2164-08-1 3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione Lenacil C13H18N2O2 O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3 InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Not reported 7 Male oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Belgium Lenacil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil 07Oct2009 2009 doi:10.2903/j.efsa.2009.1326
+Lenacil 218-499-0 2164-08-1 single chemical entity Component is identical to the substance Lenacil 218-499-0 2164-08-1 3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione Lenacil C13H18N2O2 O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3 InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Not reported 7 Male oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Belgium Lenacil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil 07Oct2009 2009 doi:10.2903/j.efsa.2009.1326
+Iron sulfate anhydrous 231-753-5 7720-78-7 single chemical entity Component is identical to the substance Iron sulfate anhydrous 231-753-5 7720-78-7 Iron(2+);sulfate Not in list FeO4S [O-]S(=O)(=O)[O-].[Fe+2] InChI=1S/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: The United Kingdom Iron sulphate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iron sulfate 25Jan2012 2012 doi:10.2903/j.efsa.2012.2521
+Iron sulfate anhydrous 231-753-5 7720-78-7 single chemical entity Component is identical to the substance Iron sulfate anhydrous 231-753-5 7720-78-7 Iron(2+);sulfate Not in list FeO4S [O-]S(=O)(=O)[O-].[Fe+2] InChI=1S/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: The United Kingdom Iron sulphate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iron sulfate 25Jan2012 2012 doi:10.2903/j.efsa.2012.2521
+Iron sulfate anhydrous 231-753-5 7720-78-7 single chemical entity Component is identical to the substance Iron sulfate anhydrous 231-753-5 7720-78-7 Iron(2+);sulfate Not in list FeO4S [O-]S(=O)(=O)[O-].[Fe+2] InChI=1S/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: The United Kingdom Iron sulphate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iron sulfate 25Jan2012 2012 doi:10.2903/j.efsa.2012.2521
+Iron sulfate anhydrous 231-753-5 7720-78-7 single chemical entity Component is identical to the substance Iron sulfate anhydrous 231-753-5 7720-78-7 Iron(2+);sulfate Not in list FeO4S [O-]S(=O)(=O)[O-].[Fe+2] InChI=1S/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: The United Kingdom Iron sulphate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iron sulfate 25Jan2012 2012 doi:10.2903/j.efsa.2012.2521
+Iron sulfate anhydrous 231-753-5 7720-78-7 single chemical entity Component is identical to the substance Iron sulfate anhydrous 231-753-5 7720-78-7 Iron(2+);sulfate Not in list FeO4S [O-]S(=O)(=O)[O-].[Fe+2] InChI=1S/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: The United Kingdom Iron sulphate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iron sulfate 25Jan2012 2012 doi:10.2903/j.efsa.2012.2521
+Iron sulfate anhydrous 231-753-5 7720-78-7 single chemical entity Component is identical to the substance Iron sulfate anhydrous 231-753-5 7720-78-7 Iron(2+);sulfate Not in list FeO4S [O-]S(=O)(=O)[O-].[Fe+2] InChI=1S/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA94 Not reported no data without Negative RMS: The United Kingdom Iron sulphate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iron sulfate 25Jan2012 2012 doi:10.2903/j.efsa.2012.2521
+Iron sulfate anhydrous 231-753-5 7720-78-7 single chemical entity Component is identical to the substance Iron sulfate anhydrous 231-753-5 7720-78-7 Iron(2+);sulfate Not in list FeO4S [O-]S(=O)(=O)[O-].[Fe+2] InChI=1S/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA94 Not reported no data with Negative RMS: The United Kingdom Iron sulphate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iron sulfate 25Jan2012 2012 doi:10.2903/j.efsa.2012.2521
+Iron sulfate anhydrous 231-753-5 7720-78-7 single chemical entity Component is identical to the substance Iron sulfate anhydrous 231-753-5 7720-78-7 Iron(2+);sulfate Not in list FeO4S [O-]S(=O)(=O)[O-].[Fe+2] InChI=1S/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: The United Kingdom Iron sulphate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iron sulfate 25Jan2012 2012 doi:10.2903/j.efsa.2012.2521
+Iron sulfate anhydrous 231-753-5 7720-78-7 single chemical entity Component is identical to the substance Iron sulfate anhydrous 231-753-5 7720-78-7 Iron(2+);sulfate Not in list FeO4S [O-]S(=O)(=O)[O-].[Fe+2] InChI=1S/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: The United Kingdom Iron sulphate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iron sulfate 25Jan2012 2012 doi:10.2903/j.efsa.2012.2521
+Iron sulfate anhydrous 231-753-5 7720-78-7 single chemical entity Component is identical to the substance Iron sulfate anhydrous 231-753-5 7720-78-7 Iron(2+);sulfate Not in list FeO4S [O-]S(=O)(=O)[O-].[Fe+2] InChI=1S/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: The United Kingdom Iron sulphate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iron sulfate 25Jan2012 2012 doi:10.2903/j.efsa.2012.2521
+Iron sulfate anhydrous 231-753-5 7720-78-7 single chemical entity Component is identical to the substance Iron sulfate anhydrous 231-753-5 7720-78-7 Iron(2+);sulfate Not in list FeO4S [O-]S(=O)(=O)[O-].[Fe+2] InChI=1S/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA92 Not reported no data without Negative RMS: The United Kingdom Iron sulphate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iron sulfate 25Jan2012 2012 doi:10.2903/j.efsa.2012.2521
+Iron sulfate anhydrous 231-753-5 7720-78-7 single chemical entity Component is identical to the substance Iron sulfate anhydrous 231-753-5 7720-78-7 Iron(2+);sulfate Not in list FeO4S [O-]S(=O)(=O)[O-].[Fe+2] InChI=1S/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA92 Not reported no data with Negative RMS: The United Kingdom Iron sulphate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iron sulfate 25Jan2012 2012 doi:10.2903/j.efsa.2012.2521
+Iron sulfate anhydrous 231-753-5 7720-78-7 single chemical entity Component is identical to the substance Iron sulfate anhydrous 231-753-5 7720-78-7 Iron(2+);sulfate Not in list FeO4S [O-]S(=O)(=O)[O-].[Fe+2] InChI=1S/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data without Positive RMS: The United Kingdom Iron sulphate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iron sulfate 25Jan2012 2012 doi:10.2903/j.efsa.2012.2521
+Iron sulfate anhydrous 231-753-5 7720-78-7 single chemical entity Component is identical to the substance Iron sulfate anhydrous 231-753-5 7720-78-7 Iron(2+);sulfate Not in list FeO4S [O-]S(=O)(=O)[O-].[Fe+2] InChI=1S/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration other in vitro No guideline available Not reported Not applicable Acceptable Saccharomyces cerevisiae (as organism) DIS13 Not reported no data without Negative RMS: The United Kingdom Iron sulphate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iron sulfate 25Jan2012 2012 doi:10.2903/j.efsa.2012.2521
+Iron sulfate anhydrous 231-753-5 7720-78-7 single chemical entity Component is identical to the substance Iron sulfate anhydrous 231-753-5 7720-78-7 Iron(2+);sulfate Not in list FeO4S [O-]S(=O)(=O)[O-].[Fe+2] InChI=1S/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Rat (as animal) Not reported yes with Negative RMS: The United Kingdom Iron sulphate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iron sulfate 25Jan2012 2012 doi:10.2903/j.efsa.2012.2521
+Iron sulfate anhydrous 231-753-5 7720-78-7 single chemical entity Component is identical to the substance Iron sulfate anhydrous 231-753-5 7720-78-7 Iron(2+);sulfate Not in list FeO4S [O-]S(=O)(=O)[O-].[Fe+2] InChI=1S/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Rat (as animal) Not reported yes without Positive RMS: The United Kingdom Iron sulphate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iron sulfate 25Jan2012 2012 doi:10.2903/j.efsa.2012.2521
+Iron sulfate anhydrous 231-753-5 7720-78-7 single chemical entity Component is identical to the substance Iron sulfate anhydrous 231-753-5 7720-78-7 Iron(2+);sulfate Not in list FeO4S [O-]S(=O)(=O)[O-].[Fe+2] InChI=1S/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Rat (as animal) hepatocytes Not reported yes without Negative RMS: The United Kingdom Iron sulphate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iron sulfate 25Jan2012 2012 doi:10.2903/j.efsa.2012.2521
+Iron sulfate anhydrous 231-753-5 7720-78-7 single chemical entity Component is identical to the substance Iron sulfate anhydrous 231-753-5 7720-78-7 Iron(2+);sulfate Not in list FeO4S [O-]S(=O)(=O)[O-].[Fe+2] InChI=1S/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair SOS/umu test in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) PQ37 Not reported no data without Negative RMS: The United Kingdom Iron sulphate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iron sulfate 25Jan2012 2012 doi:10.2903/j.efsa.2012.2521
+Iron sulfate anhydrous 231-753-5 7720-78-7 single chemical entity Component is identical to the substance Iron sulfate anhydrous 231-753-5 7720-78-7 Iron(2+);sulfate Not in list FeO4S [O-]S(=O)(=O)[O-].[Fe+2] InChI=1S/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) C57BL 5 Female oral: gavage 24.0000000000 h yes not applicable Negative no evidence RMS: The United Kingdom Iron sulphate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iron sulfate 25Jan2012 2012 doi:10.2903/j.efsa.2012.2521
+Iron sulfate anhydrous 231-753-5 7720-78-7 single chemical entity Component is identical to the substance Iron sulfate anhydrous 231-753-5 7720-78-7 Iron(2+);sulfate Not in list FeO4S [O-]S(=O)(=O)[O-].[Fe+2] InChI=1S/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) C57BL 5 Female other 24.0000000000 h yes not applicable Negative no evidence RMS: The United Kingdom Iron sulphate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iron sulfate 25Jan2012 2012 doi:10.2903/j.efsa.2012.2521
+Iron sulfate anhydrous 231-753-5 7720-78-7 single chemical entity Component is identical to the substance Iron sulfate anhydrous 231-753-5 7720-78-7 Iron(2+);sulfate Not in list FeO4S [O-]S(=O)(=O)[O-].[Fe+2] InChI=1S/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) C57BL 5 Female oral: gavage 24.0000000000 h no data not applicable Negative no evidence RMS: The United Kingdom Iron sulphate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iron sulfate 25Jan2012 2012 doi:10.2903/j.efsa.2012.2521
+Iron sulfate anhydrous 231-753-5 7720-78-7 single chemical entity Component is identical to the substance Iron sulfate anhydrous 231-753-5 7720-78-7 Iron(2+);sulfate Not in list FeO4S [O-]S(=O)(=O)[O-].[Fe+2] InChI=1S/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) C57BL 5 Female oral: gavage 24.0000000000 h yes not applicable Negative no evidence RMS: The United Kingdom Iron sulphate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iron sulfate 25Jan2012 2012 doi:10.2903/j.efsa.2012.2521
+Iron sulfate anhydrous 231-753-5 7720-78-7 single chemical entity Component is identical to the substance Iron sulfate anhydrous 231-753-5 7720-78-7 Iron(2+);sulfate Not in list FeO4S [O-]S(=O)(=O)[O-].[Fe+2] InChI=1S/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) C57BL 5 Female other 24.0000000000 h yes not applicable Negative no evidence RMS: The United Kingdom Iron sulphate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iron sulfate 25Jan2012 2012 doi:10.2903/j.efsa.2012.2521
+Iron sulfate anhydrous 231-753-5 7720-78-7 single chemical entity Component is identical to the substance Iron sulfate anhydrous 231-753-5 7720-78-7 Iron(2+);sulfate Not in list FeO4S [O-]S(=O)(=O)[O-].[Fe+2] InChI=1S/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) C57BL 5 Female other 24.0000000000 h yes not applicable Negative no evidence RMS: The United Kingdom Iron sulphate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iron sulfate 25Jan2012 2012 doi:10.2903/j.efsa.2012.2521
+Iron sulfate anhydrous 231-753-5 7720-78-7 single chemical entity Component is identical to the substance Iron sulfate anhydrous 231-753-5 7720-78-7 Iron(2+);sulfate Not in list FeO4S [O-]S(=O)(=O)[O-].[Fe+2] InChI=1S/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) ddy mouse 6 Male intraperitoneal 24.0000000000 h no data not applicable Negative no evidence RMS: The United Kingdom Iron sulphate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iron sulfate 25Jan2012 2012 doi:10.2903/j.efsa.2012.2521
+Iron sulfate anhydrous 231-753-5 7720-78-7 single chemical entity Component is identical to the substance Iron sulfate anhydrous 231-753-5 7720-78-7 Iron(2+);sulfate Not in list FeO4S [O-]S(=O)(=O)[O-].[Fe+2] InChI=1S/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair in vitro mammalian cell transformation assay in vitro No guideline available Not reported Not applicable Acceptable Hamster (as animal) embryo cells Not reported no data without Negative RMS: The United Kingdom Iron sulphate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iron sulfate 25Jan2012 2012 doi:10.2903/j.efsa.2012.2521
+Iron sulfate anhydrous 231-753-5 7720-78-7 single chemical entity Component is identical to the substance Iron sulfate anhydrous 231-753-5 7720-78-7 Iron(2+);sulfate Not in list FeO4S [O-]S(=O)(=O)[O-].[Fe+2] InChI=1S/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair in vitro mammalian cell transformation assay in vitro No guideline available Not reported Not applicable Acceptable Rat (as animal) kidney cells Not reported no data without Negative RMS: The United Kingdom Iron sulphate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance iron sulfate 25Jan2012 2012 doi:10.2903/j.efsa.2012.2521
+Kresoxim-methyl 143390-89-0 single chemical entity Component is a metabolite of the substance (E)-methoxyamino(α-(o-tolyloxy)-o-tolyl]acetic acid (2E)-(methoxyimino){2-[(2-methylphenoxy)methyl]phenyl}ethanoic acid Not in list C17H17NO4 O=C(O)\C(=N\OC)c2ccccc2COc1ccccc1C InChI=1/C17H17NO4/c1-12-7-3-6-10-15(12)22-11-13-8-4-5-9-14(13)16(17(19)20)18-21-2/h3-10H,11H2,1-2H3,(H,19,20)/b18-16+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is a metabolite of the substance (E)-methoxyamino(α-(o-tolyloxy)-o-tolyl]acetic acid (2E)-(methoxyimino){2-[(2-methylphenoxy)methyl]phenyl}ethanoic acid Not in list C17H17NO4 O=C(O)\C(=N\OC)c2ccccc2COc1ccccc1C InChI=1/C17H17NO4/c1-12-7-3-6-10-15(12)22-11-13-8-4-5-9-14(13)16(17(19)20)18-21-2/h3-10H,11H2,1-2H3,(H,19,20)/b18-16+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is a metabolite of the substance (E)-methoxyamino(α-(o-tolyloxy)-o-tolyl]acetic acid (2E)-(methoxyimino){2-[(2-methylphenoxy)methyl]phenyl}ethanoic acid Not in list C17H17NO4 O=C(O)\C(=N\OC)c2ccccc2COc1ccccc1C InChI=1/C17H17NO4/c1-12-7-3-6-10-15(12)22-11-13-8-4-5-9-14(13)16(17(19)20)18-21-2/h3-10H,11H2,1-2H3,(H,19,20)/b18-16+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is a metabolite of the substance (E)-methoxyamino(α-(o-tolyloxy)-o-tolyl]acetic acid (2E)-(methoxyimino){2-[(2-methylphenoxy)methyl]phenyl}ethanoic acid Not in list C17H17NO4 O=C(O)\C(=N\OC)c2ccccc2COc1ccccc1C InChI=1/C17H17NO4/c1-12-7-3-6-10-15(12)22-11-13-8-4-5-9-14(13)16(17(19)20)18-21-2/h3-10H,11H2,1-2H3,(H,19,20)/b18-16+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is a metabolite of the substance (E)-methoxyamino(α-(o-tolyloxy)-o-tolyl]acetic acid (2E)-(methoxyimino){2-[(2-methylphenoxy)methyl]phenyl}ethanoic acid Not in list C17H17NO4 O=C(O)\C(=N\OC)c2ccccc2COc1ccccc1C InChI=1/C17H17NO4/c1-12-7-3-6-10-15(12)22-11-13-8-4-5-9-14(13)16(17(19)20)18-21-2/h3-10H,11H2,1-2H3,(H,19,20)/b18-16+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is a metabolite of the substance (E)-methoxyamino(α-(o-tolyloxy)-o-tolyl]acetic acid (2E)-(methoxyimino){2-[(2-methylphenoxy)methyl]phenyl}ethanoic acid Not in list C17H17NO4 O=C(O)\C(=N\OC)c2ccccc2COc1ccccc1C InChI=1/C17H17NO4/c1-12-7-3-6-10-15(12)22-11-13-8-4-5-9-14(13)16(17(19)20)18-21-2/h3-10H,11H2,1-2H3,(H,19,20)/b18-16+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is a metabolite of the substance (E)-methoxyamino(α-(o-tolyloxy)-o-tolyl]acetic acid (2E)-(methoxyimino){2-[(2-methylphenoxy)methyl]phenyl}ethanoic acid Not in list C17H17NO4 O=C(O)\C(=N\OC)c2ccccc2COc1ccccc1C InChI=1/C17H17NO4/c1-12-7-3-6-10-15(12)22-11-13-8-4-5-9-14(13)16(17(19)20)18-21-2/h3-10H,11H2,1-2H3,(H,19,20)/b18-16+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is a metabolite of the substance (E)-methoxyamino(α-(o-tolyloxy)-o-tolyl]acetic acid (2E)-(methoxyimino){2-[(2-methylphenoxy)methyl]phenyl}ethanoic acid Not in list C17H17NO4 O=C(O)\C(=N\OC)c2ccccc2COc1ccccc1C InChI=1/C17H17NO4/c1-12-7-3-6-10-15(12)22-11-13-8-4-5-9-14(13)16(17(19)20)18-21-2/h3-10H,11H2,1-2H3,(H,19,20)/b18-16+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is a metabolite of the substance (E)-methoxyamino(α-(o-tolyloxy)-o-tolyl]acetic acid (2E)-(methoxyimino){2-[(2-methylphenoxy)methyl]phenyl}ethanoic acid Not in list C17H17NO4 O=C(O)\C(=N\OC)c2ccccc2COc1ccccc1C InChI=1/C17H17NO4/c1-12-7-3-6-10-15(12)22-11-13-8-4-5-9-14(13)16(17(19)20)18-21-2/h3-10H,11H2,1-2H3,(H,19,20)/b18-16+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Kresoxim-methyl 143390-89-0 single chemical entity Component is a metabolite of the substance (E)-methoxyamino(α-(o-tolyloxy)-o-tolyl]acetic acid (2E)-(methoxyimino){2-[(2-methylphenoxy)methyl]phenyl}ethanoic acid Not in list C17H17NO4 O=C(O)\C(=N\OC)c2ccccc2COc1ccccc1C InChI=1/C17H17NO4/c1-12-7-3-6-10-15(12)22-11-13-8-4-5-9-14(13)16(17(19)20)18-21-2/h3-10H,11H2,1-2H3,(H,19,20)/b18-16+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Lithuania Kresoxim-methyl 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl 19Nov2010 2010 doi:10.2903/j.efsa.2010.1891
+Isopyrazam 881685-58-1 single chemical entity Component is identical to the substance Isopyrazam 881685-58-1 3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide Isopyrazam C20H23F2N3O FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23 InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26) organic representative compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is identical to the substance Isopyrazam 881685-58-1 3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide Isopyrazam C20H23F2N3O FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23 InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26) organic representative compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is identical to the substance Isopyrazam 881685-58-1 3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide Isopyrazam C20H23F2N3O FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23 InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26) organic representative compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is identical to the substance Isopyrazam 881685-58-1 3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide Isopyrazam C20H23F2N3O FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23 InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26) organic representative compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is identical to the substance Isopyrazam 881685-58-1 3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide Isopyrazam C20H23F2N3O FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23 InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26) organic representative compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is identical to the substance Isopyrazam 881685-58-1 3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide Isopyrazam C20H23F2N3O FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23 InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26) organic representative compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is identical to the substance Isopyrazam 881685-58-1 3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide Isopyrazam C20H23F2N3O FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23 InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26) organic representative compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is identical to the substance Isopyrazam 881685-58-1 3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide Isopyrazam C20H23F2N3O FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23 InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26) organic representative compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is identical to the substance Isopyrazam 881685-58-1 3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide Isopyrazam C20H23F2N3O FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23 InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26) organic representative compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is identical to the substance Isopyrazam 881685-58-1 3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide Isopyrazam C20H23F2N3O FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23 InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26) organic representative compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is identical to the substance Isopyrazam 881685-58-1 3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide Isopyrazam C20H23F2N3O FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23 InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26) organic representative compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is identical to the substance Isopyrazam 881685-58-1 3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide Isopyrazam C20H23F2N3O FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23 InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26) organic representative compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is identical to the substance Isopyrazam 881685-58-1 3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide Isopyrazam C20H23F2N3O FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23 InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26) organic representative compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is identical to the substance Isopyrazam 881685-58-1 3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide Isopyrazam C20H23F2N3O FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23 InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26) organic representative compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is identical to the substance Isopyrazam 881685-58-1 3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide Isopyrazam C20H23F2N3O FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23 InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26) organic representative compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is identical to the substance Isopyrazam 881685-58-1 3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide Isopyrazam C20H23F2N3O FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23 InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26) organic representative compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is identical to the substance Isopyrazam 881685-58-1 3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide Isopyrazam C20H23F2N3O FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23 InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26) organic representative compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is identical to the substance Isopyrazam 881685-58-1 3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide Isopyrazam C20H23F2N3O FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23 InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26) organic representative compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is identical to the substance Isopyrazam 881685-58-1 3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide Isopyrazam C20H23F2N3O FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23 InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26) organic representative compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is identical to the substance Isopyrazam 881685-58-1 3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide Isopyrazam C20H23F2N3O FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23 InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26) organic representative compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is identical to the substance Isopyrazam 881685-58-1 3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide Isopyrazam C20H23F2N3O FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23 InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26) organic representative compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is identical to the substance Isopyrazam 881685-58-1 3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide Isopyrazam C20H23F2N3O FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23 InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26) organic representative compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is identical to the substance Isopyrazam 881685-58-1 3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide Isopyrazam C20H23F2N3O FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23 InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26) organic representative compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is identical to the substance Isopyrazam 881685-58-1 3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide Isopyrazam C20H23F2N3O FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23 InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26) organic representative compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is identical to the substance Isopyrazam 881685-58-1 3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide Isopyrazam C20H23F2N3O FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23 InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26) organic representative compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is identical to the substance Isopyrazam 881685-58-1 3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide Isopyrazam C20H23F2N3O FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23 InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26) organic representative compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is identical to the substance Isopyrazam 881685-58-1 3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide Isopyrazam C20H23F2N3O FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23 InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26) organic representative compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is identical to the substance Isopyrazam 881685-58-1 3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide Isopyrazam C20H23F2N3O FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23 InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26) organic representative compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is identical to the substance Isopyrazam 881685-58-1 3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide Isopyrazam C20H23F2N3O FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23 InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26) organic representative compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Negative small colonies RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is identical to the substance Isopyrazam 881685-58-1 3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide Isopyrazam C20H23F2N3O FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23 InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26) organic representative compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Negative large colonies RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is identical to the substance Isopyrazam 881685-58-1 3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide Isopyrazam C20H23F2N3O FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23 InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26) organic representative compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative large colonies RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is identical to the substance Isopyrazam 881685-58-1 3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide Isopyrazam C20H23F2N3O FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23 InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26) organic representative compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative small colonies RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is identical to the substance Isopyrazam 881685-58-1 3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide Isopyrazam C20H23F2N3O FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23 InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26) organic representative compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative large colonies RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is identical to the substance Isopyrazam 881685-58-1 3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide Isopyrazam C20H23F2N3O FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23 InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26) organic representative compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Negative large colonies RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is identical to the substance Isopyrazam 881685-58-1 3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide Isopyrazam C20H23F2N3O FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23 InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26) organic representative compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative small colonies RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is identical to the substance Isopyrazam 881685-58-1 3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide Isopyrazam C20H23F2N3O FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23 InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26) organic representative compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Negative small colonies RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is identical to the substance Isopyrazam 881685-58-1 3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide Isopyrazam C20H23F2N3O FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23 InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26) organic representative compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable Rat (as animal) Wistar 5 Male oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is identical to the substance Isopyrazam 881685-58-1 3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide Isopyrazam C20H23F2N3O FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23 InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26) organic representative compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable Rat (as animal) Wistar 5 Male oral: unspecified 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is identical to the substance Isopyrazam 881685-58-1 3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide Isopyrazam C20H23F2N3O FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23 InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26) organic representative compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Wistar 3 Male oral: unspecified 2.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is identical to the substance Isopyrazam 881685-58-1 3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide Isopyrazam C20H23F2N3O FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23 InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26) organic representative compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Wistar 3 Male oral: unspecified 16.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C5H4F2N2O2 FC(F)c1nncc1C(=O)O InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C5H4F2N2O2 FC(F)c1nncc1C(=O)O InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C5H4F2N2O2 FC(F)c1nncc1C(=O)O InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C5H4F2N2O2 FC(F)c1nncc1C(=O)O InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C5H4F2N2O2 FC(F)c1nncc1C(=O)O InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C5H4F2N2O2 FC(F)c1nncc1C(=O)O InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C5H4F2N2O2 FC(F)c1nncc1C(=O)O InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C5H4F2N2O2 FC(F)c1nncc1C(=O)O InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C5H4F2N2O2 FC(F)c1nncc1C(=O)O InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C5H4F2N2O2 FC(F)c1nncc1C(=O)O InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C5H4F2N2O2 FC(F)c1nncc1C(=O)O InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C5H4F2N2O2 FC(F)c1nncc1C(=O)O InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C5H4F2N2O2 FC(F)c1nncc1C(=O)O InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported no data with Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C5H4F2N2O2 FC(F)c1nncc1C(=O)O InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported no data without Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C5H4F2N2O2 FC(F)c1nncc1C(=O)O InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data without Negative small colonies RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C5H4F2N2O2 FC(F)c1nncc1C(=O)O InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data without Negative large colonies RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C5H4F2N2O2 FC(F)c1nncc1C(=O)O InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data with Negative large colonies RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C5H4F2N2O2 FC(F)c1nncc1C(=O)O InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data with Negative small colonies RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is a metabolite of the substance 3-(difluoromethyl)-1-methyl-N-[(1S,4R,9S)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide 3-(difluoromethyl)-N-[(1R,8S,11S)-11-(2-hydroxypropan-2-yl)tricyclo[6.2.1.02,7]undeca-2,4,6-trien-3-yl]-1-methyl-1H-pyrazole-4-carboxamide Not in list C20H23F2N3O2 FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@H]1CC[C@H]([C@H]1C(C)(C)O)c23 InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is a metabolite of the substance 3-(difluoromethyl)-1-methyl-N-[(1S,4R,9S)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide 3-(difluoromethyl)-N-[(1R,8S,11S)-11-(2-hydroxypropan-2-yl)tricyclo[6.2.1.02,7]undeca-2,4,6-trien-3-yl]-1-methyl-1H-pyrazole-4-carboxamide Not in list C20H23F2N3O2 FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@H]1CC[C@H]([C@H]1C(C)(C)O)c23 InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is a metabolite of the substance 3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide 3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide Not in list C20H23F2N3O2 FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@@H]1CC[C@@H]([C@@H]1C(C)(C)O)c23 InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is a metabolite of the substance 3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide 3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide Not in list C20H23F2N3O2 FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@@H]1CC[C@@H]([C@@H]1C(C)(C)O)c23 InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is a metabolite of the substance 3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide 3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide Not in list C20H23F2N3O2 FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@@H]1CC[C@@H]([C@@H]1C(C)(C)O)c23 InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is a metabolite of the substance 3-(difluoromethyl)-1-methyl-N-[(1S,4R,9S)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide 3-(difluoromethyl)-N-[(1R,8S,11S)-11-(2-hydroxypropan-2-yl)tricyclo[6.2.1.02,7]undeca-2,4,6-trien-3-yl]-1-methyl-1H-pyrazole-4-carboxamide Not in list C20H23F2N3O2 FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@H]1CC[C@H]([C@H]1C(C)(C)O)c23 InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is a metabolite of the substance 3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide 3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide Not in list C20H23F2N3O2 FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@@H]1CC[C@@H]([C@@H]1C(C)(C)O)c23 InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is a metabolite of the substance 3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide 3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide Not in list C20H23F2N3O2 FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@@H]1CC[C@@H]([C@@H]1C(C)(C)O)c23 InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is a metabolite of the substance 3-(difluoromethyl)-1-methyl-N-[(1S,4R,9S)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide 3-(difluoromethyl)-N-[(1R,8S,11S)-11-(2-hydroxypropan-2-yl)tricyclo[6.2.1.02,7]undeca-2,4,6-trien-3-yl]-1-methyl-1H-pyrazole-4-carboxamide Not in list C20H23F2N3O2 FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@H]1CC[C@H]([C@H]1C(C)(C)O)c23 InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is a metabolite of the substance 3-(difluoromethyl)-1-methyl-N-[(1S,4R,9S)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide 3-(difluoromethyl)-N-[(1R,8S,11S)-11-(2-hydroxypropan-2-yl)tricyclo[6.2.1.02,7]undeca-2,4,6-trien-3-yl]-1-methyl-1H-pyrazole-4-carboxamide Not in list C20H23F2N3O2 FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@H]1CC[C@H]([C@H]1C(C)(C)O)c23 InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is a metabolite of the substance 3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide 3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide Not in list C20H23F2N3O2 FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@@H]1CC[C@@H]([C@@H]1C(C)(C)O)c23 InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is a metabolite of the substance 3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide 3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide Not in list C20H23F2N3O2 FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@@H]1CC[C@@H]([C@@H]1C(C)(C)O)c23 InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is a metabolite of the substance 3-(difluoromethyl)-1-methyl-N-[(1S,4R,9S)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide 3-(difluoromethyl)-N-[(1R,8S,11S)-11-(2-hydroxypropan-2-yl)tricyclo[6.2.1.02,7]undeca-2,4,6-trien-3-yl]-1-methyl-1H-pyrazole-4-carboxamide Not in list C20H23F2N3O2 FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@H]1CC[C@H]([C@H]1C(C)(C)O)c23 InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is a metabolite of the substance 3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide 3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide Not in list C20H23F2N3O2 FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@@H]1CC[C@@H]([C@@H]1C(C)(C)O)c23 InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is a metabolite of the substance 3-(difluoromethyl)-1-methyl-N-[(1S,4R,9S)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide 3-(difluoromethyl)-N-[(1R,8S,11S)-11-(2-hydroxypropan-2-yl)tricyclo[6.2.1.02,7]undeca-2,4,6-trien-3-yl]-1-methyl-1H-pyrazole-4-carboxamide Not in list C20H23F2N3O2 FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@H]1CC[C@H]([C@H]1C(C)(C)O)c23 InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is a metabolite of the substance 3-(difluoromethyl)-1-methyl-N-[(1S,4R,9S)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide 3-(difluoromethyl)-N-[(1R,8S,11S)-11-(2-hydroxypropan-2-yl)tricyclo[6.2.1.02,7]undeca-2,4,6-trien-3-yl]-1-methyl-1H-pyrazole-4-carboxamide Not in list C20H23F2N3O2 FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@H]1CC[C@H]([C@H]1C(C)(C)O)c23 InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is a metabolite of the substance 3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide 3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide Not in list C20H23F2N3O2 FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@@H]1CC[C@@H]([C@@H]1C(C)(C)O)c23 InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is a metabolite of the substance 3-(difluoromethyl)-1-methyl-N-[(1S,4R,9S)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide 3-(difluoromethyl)-N-[(1R,8S,11S)-11-(2-hydroxypropan-2-yl)tricyclo[6.2.1.02,7]undeca-2,4,6-trien-3-yl]-1-methyl-1H-pyrazole-4-carboxamide Not in list C20H23F2N3O2 FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@H]1CC[C@H]([C@H]1C(C)(C)O)c23 InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is a metabolite of the substance 3-(difluoromethyl)-1-methyl-N-[(1S,4R,9S)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide 3-(difluoromethyl)-N-[(1R,8S,11S)-11-(2-hydroxypropan-2-yl)tricyclo[6.2.1.02,7]undeca-2,4,6-trien-3-yl]-1-methyl-1H-pyrazole-4-carboxamide Not in list C20H23F2N3O2 FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@H]1CC[C@H]([C@H]1C(C)(C)O)c23 InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is a metabolite of the substance 3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide 3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide Not in list C20H23F2N3O2 FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@@H]1CC[C@@H]([C@@H]1C(C)(C)O)c23 InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is a metabolite of the substance 3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide 3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide Not in list C20H23F2N3O2 FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@@H]1CC[C@@H]([C@@H]1C(C)(C)O)c23 InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is a metabolite of the substance 3-(difluoromethyl)-1-methyl-N-[(1S,4R,9S)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide 3-(difluoromethyl)-N-[(1R,8S,11S)-11-(2-hydroxypropan-2-yl)tricyclo[6.2.1.02,7]undeca-2,4,6-trien-3-yl]-1-methyl-1H-pyrazole-4-carboxamide Not in list C20H23F2N3O2 FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@H]1CC[C@H]([C@H]1C(C)(C)O)c23 InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is a metabolite of the substance 3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide 3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide Not in list C20H23F2N3O2 FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@@H]1CC[C@@H]([C@@H]1C(C)(C)O)c23 InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is a metabolite of the substance 3-(difluoromethyl)-1-methyl-N-[(1S,4R,9S)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide 3-(difluoromethyl)-N-[(1R,8S,11S)-11-(2-hydroxypropan-2-yl)tricyclo[6.2.1.02,7]undeca-2,4,6-trien-3-yl]-1-methyl-1H-pyrazole-4-carboxamide Not in list C20H23F2N3O2 FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@H]1CC[C@H]([C@H]1C(C)(C)O)c23 InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is a metabolite of the substance 3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide 3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide Not in list C20H23F2N3O2 FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@@H]1CC[C@@H]([C@@H]1C(C)(C)O)c23 InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m0/s1 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported no data without Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is a metabolite of the substance 3-(difluoromethyl)-1-methyl-N-[(1S,4R,9S)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide 3-(difluoromethyl)-N-[(1R,8S,11S)-11-(2-hydroxypropan-2-yl)tricyclo[6.2.1.02,7]undeca-2,4,6-trien-3-yl]-1-methyl-1H-pyrazole-4-carboxamide Not in list C20H23F2N3O2 FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@H]1CC[C@H]([C@H]1C(C)(C)O)c23 InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m1/s1 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported no data with Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is a metabolite of the substance 3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide 3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide Not in list C20H23F2N3O2 FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@@H]1CC[C@@H]([C@@H]1C(C)(C)O)c23 InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m0/s1 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported no data with Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is a metabolite of the substance 3-(difluoromethyl)-1-methyl-N-[(1S,4R,9S)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide 3-(difluoromethyl)-N-[(1R,8S,11S)-11-(2-hydroxypropan-2-yl)tricyclo[6.2.1.02,7]undeca-2,4,6-trien-3-yl]-1-methyl-1H-pyrazole-4-carboxamide Not in list C20H23F2N3O2 FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@H]1CC[C@H]([C@H]1C(C)(C)O)c23 InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m1/s1 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported no data without Negative RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is a metabolite of the substance 3-(difluoromethyl)-1-methyl-N-[(1S,4R,9S)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide 3-(difluoromethyl)-N-[(1R,8S,11S)-11-(2-hydroxypropan-2-yl)tricyclo[6.2.1.02,7]undeca-2,4,6-trien-3-yl]-1-methyl-1H-pyrazole-4-carboxamide Not in list C20H23F2N3O2 FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@H]1CC[C@H]([C@H]1C(C)(C)O)c23 InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m1/s1 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 72.0000000000 h yes not applicable Negative no evidence RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is a metabolite of the substance 3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide 3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide Not in list C20H23F2N3O2 FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@@H]1CC[C@@H]([C@@H]1C(C)(C)O)c23 InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m0/s1 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data without Negative small colonies RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is a metabolite of the substance 3-(difluoromethyl)-1-methyl-N-[(1S,4R,9S)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide 3-(difluoromethyl)-N-[(1R,8S,11S)-11-(2-hydroxypropan-2-yl)tricyclo[6.2.1.02,7]undeca-2,4,6-trien-3-yl]-1-methyl-1H-pyrazole-4-carboxamide Not in list C20H23F2N3O2 FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@H]1CC[C@H]([C@H]1C(C)(C)O)c23 InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m1/s1 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data with Negative small colonies RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is a metabolite of the substance 3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide 3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide Not in list C20H23F2N3O2 FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@@H]1CC[C@@H]([C@@H]1C(C)(C)O)c23 InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m0/s1 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data without Negative large colonies RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is a metabolite of the substance 3-(difluoromethyl)-1-methyl-N-[(1S,4R,9S)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide 3-(difluoromethyl)-N-[(1R,8S,11S)-11-(2-hydroxypropan-2-yl)tricyclo[6.2.1.02,7]undeca-2,4,6-trien-3-yl]-1-methyl-1H-pyrazole-4-carboxamide Not in list C20H23F2N3O2 FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@H]1CC[C@H]([C@H]1C(C)(C)O)c23 InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m1/s1 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data without Negative large colonies RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is a metabolite of the substance 3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide 3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide Not in list C20H23F2N3O2 FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@@H]1CC[C@@H]([C@@H]1C(C)(C)O)c23 InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m0/s1 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data with Negative large colonies RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is a metabolite of the substance 3-(difluoromethyl)-1-methyl-N-[(1S,4R,9S)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide 3-(difluoromethyl)-N-[(1R,8S,11S)-11-(2-hydroxypropan-2-yl)tricyclo[6.2.1.02,7]undeca-2,4,6-trien-3-yl]-1-methyl-1H-pyrazole-4-carboxamide Not in list C20H23F2N3O2 FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@H]1CC[C@H]([C@H]1C(C)(C)O)c23 InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m1/s1 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data without Negative small colonies RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Isopyrazam 881685-58-1 single chemical entity Component is a metabolite of the substance 3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide 3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide Not in list C20H23F2N3O2 FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@@H]1CC[C@@H]([C@@H]1C(C)(C)O)c23 InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m0/s1 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data with Negative small colonies RMS: The United Kingdom Isopyrazam 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam 29Mar2012 2012 doi:10.2903/j.efsa.2012.2600
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Finland Malathion 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Finland Malathion 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Finland Malathion 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: Finland Malathion 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Finland Malathion 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: Finland Malathion 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Finland Malathion 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Finland Malathion 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Finland Malathion 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Finland Malathion 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: Finland Malathion 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: Finland Malathion 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes without Negative RMS: Finland Malathion 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Positive RMS: Finland Malathion 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Positive RMS: Finland Malathion 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Positive large colonies RMS: Finland Malathion 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Positive small colonies RMS: Finland Malathion 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Positive small colonies RMS: Finland Malathion 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Positive large colonies RMS: Finland Malathion 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Rat (as animal) Sprague-Dawley 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Finland Malathion 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Rat (as animal) Sprague-Dawley 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Finland Malathion 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Rat (as animal) Sprague-Dawley 10 Male/Female oral: gavage 12.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Finland Malathion 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Not reported 3 Male oral: unspecified 4.0000000000 h yes not applicable Negative RMS: Finland Malathion 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Not reported 3 Male oral: unspecified 16.0000000000 h yes not applicable Negative RMS: Finland Malathion 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Finland Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Finland Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Finland Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Finland Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Finland Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Finland Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Finland Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Finland Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Finland Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Finland Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Not reported 3 Male oral: unspecified 16.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Finland Malathion (Addendum 1) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Not reported 3 Male oral: unspecified 4.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Finland Malathion (Addendum 1) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is a metabolite of the substance diethyl (2RS)-2-{[methoxy(methylsulfanyl)phosphoryl]sulfanyl}butanedioate diethyl 2-[methoxy(methylsulfanyl)phosphoryl]sulfanylbutanedioate Not in list C10H19O6PS2 CCOC(=O)CC(C(=O)OCC)SP(=O)(OC)SC InChI=1S/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(13,14-3)18-4/h8H,5-7H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vitro No guideline available Not reported Not applicable Acceptable Human (as organism) lymphocytes Not reported no data no data Positive RMS: Finland Malathion (Addendum 1) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vitro No guideline available Not reported Not applicable Acceptable Human (as organism) lymphocytes Not reported no data no data Negative RMS: Finland Malathion (Addendum 1) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is a metabolite of the substance Diethyl (2RS)-2-[(dimethoxyphosphoryl)sulfanyl]butanedioate 1634-78-2 Diethyl 2-dimethoxyphosphorylsulfanylbutanedioate Malaoxon C10H19O7PS CCOC(=O)CC(C(=O)OCC)SP(=O)(OC)OC InChI=1S/C10H19O7PS/c1-5-16-9(11)7-8(10(12)17-6-2)19-18(13,14-3)15-4/h8H,5-7H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vitro No guideline available Not reported Not applicable Acceptable Human (as organism) lymphocytes Not reported no data no data Positive RMS: Finland Malathion (Addendum 1) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other chromosome aberration other in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) Swiss 5 Male oral: feed 12.0000000000 week yes, concurrent no treatment not applicable Negative RMS: Finland Malathion (Addendum 1) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable House mouse (as animal) Swiss 5 Male oral: feed 6.0000000000 week yes, concurrent no treatment not applicable Negative RMS: Finland Malathion (Addendum 1) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other chromosome aberration other in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) Swiss 5 Male oral: feed 12.0000000000 week yes, concurrent no treatment not applicable Positive RMS: Finland Malathion (Addendum 1) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable House mouse (as animal) Swiss 5 Male oral: feed 12.0000000000 week yes, concurrent no treatment not applicable Positive RMS: Finland Malathion (Addendum 1) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable House mouse (as animal) Swiss 5 Male oral: feed 6.0000000000 week yes, concurrent no treatment not applicable Positive RMS: Finland Malathion (Addendum 1) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable House mouse (as animal) Swiss 5 Male oral: feed 12.0000000000 week yes, concurrent no treatment not applicable Positive RMS: Finland Malathion (Addendum 1) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable House mouse (as animal) Swiss 5 Male oral: feed 6.0000000000 week yes, concurrent no treatment not applicable Positive RMS: Finland Malathion (Addendum 1) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable House mouse (as animal) Swiss 5 Male oral: feed 12.0000000000 week yes, concurrent no treatment not applicable Positive RMS: Finland Malathion (Addendum 1) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable House mouse (as animal) Swiss 5 Male oral: feed 6.0000000000 week yes, concurrent no treatment not applicable Positive RMS: Finland Malathion (Addendum 1) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable House mouse (as animal) Swiss 5 Male oral: feed 12.0000000000 week yes, concurrent no treatment not applicable Negative RMS: Finland Malathion (Addendum 1) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable House mouse (as animal) Swiss 5 Male oral: feed 12.0000000000 week yes, concurrent no treatment not applicable Negative RMS: Finland Malathion (Addendum 1) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other chromosome aberration other in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) Swiss 5 Male oral: feed 6.0000000000 week yes, concurrent no treatment not applicable Positive RMS: Finland Malathion (Addendum 1) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable House mouse (as animal) Swiss 5 Male oral: feed 12.0000000000 week yes, concurrent no treatment not applicable Negative RMS: Finland Malathion (Addendum 1) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable House mouse (as animal) Swiss 5 Male oral: feed 6.0000000000 week yes, concurrent no treatment not applicable Negative RMS: Finland Malathion (Addendum 1) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other chromosome aberration other in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) Swiss 5 Male oral: feed 6.0000000000 week yes, concurrent no treatment not applicable Negative RMS: Finland Malathion (Addendum 1) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable House mouse (as animal) Swiss 5 Male oral: feed 6.0000000000 week yes, concurrent no treatment not applicable Negative RMS: Finland Malathion (Addendum 1) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Indolylbutyric acid 205-101-5 133-32-4 single chemical entity Component is identical to the substance Indolylbutyric acid 205-101-5 133-32-4 4-(1H-indol-3-yl)butanoic acid Not in list C12H13NO2 OC(=O)CCCc1c[nH]c2ccccc12 InChI=1/C12H13NO2/c14-12(15)7-3-4-9-8-13-11-6-2-1-5-10(9)11/h1-2,5-6,8,13H,3-4,7H2,(H,14,15) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: France Indolylbutiric acid (Revised DAR of September 2007) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance indolylbutyric acid 14Sep2010 2010 doi:10.2903/j.efsa.2010.1720
+Indolylbutyric acid 205-101-5 133-32-4 single chemical entity Component is identical to the substance Indolylbutyric acid 205-101-5 133-32-4 4-(1H-indol-3-yl)butanoic acid Not in list C12H13NO2 OC(=O)CCCc1c[nH]c2ccccc12 InChI=1/C12H13NO2/c14-12(15)7-3-4-9-8-13-11-6-2-1-5-10(9)11/h1-2,5-6,8,13H,3-4,7H2,(H,14,15) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: France Indolylbutiric acid (Revised DAR of September 2007) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance indolylbutyric acid 14Sep2010 2010 doi:10.2903/j.efsa.2010.1720
+Indolylbutyric acid 205-101-5 133-32-4 single chemical entity Component is identical to the substance Indolylbutyric acid 205-101-5 133-32-4 4-(1H-indol-3-yl)butanoic acid Not in list C12H13NO2 OC(=O)CCCc1c[nH]c2ccccc12 InChI=1/C12H13NO2/c14-12(15)7-3-4-9-8-13-11-6-2-1-5-10(9)11/h1-2,5-6,8,13H,3-4,7H2,(H,14,15) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: France Indolylbutiric acid (Revised DAR of September 2007) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance indolylbutyric acid 14Sep2010 2010 doi:10.2903/j.efsa.2010.1720
+Indolylbutyric acid 205-101-5 133-32-4 single chemical entity Component is identical to the substance Indolylbutyric acid 205-101-5 133-32-4 4-(1H-indol-3-yl)butanoic acid Not in list C12H13NO2 OC(=O)CCCc1c[nH]c2ccccc12 InChI=1/C12H13NO2/c14-12(15)7-3-4-9-8-13-11-6-2-1-5-10(9)11/h1-2,5-6,8,13H,3-4,7H2,(H,14,15) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: France Indolylbutiric acid (Revised DAR of September 2007) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance indolylbutyric acid 14Sep2010 2010 doi:10.2903/j.efsa.2010.1720
+Indolylbutyric acid 205-101-5 133-32-4 single chemical entity Component is identical to the substance Indolylbutyric acid 205-101-5 133-32-4 4-(1H-indol-3-yl)butanoic acid Not in list C12H13NO2 OC(=O)CCCc1c[nH]c2ccccc12 InChI=1/C12H13NO2/c14-12(15)7-3-4-9-8-13-11-6-2-1-5-10(9)11/h1-2,5-6,8,13H,3-4,7H2,(H,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Indolylbutiric acid (Revised DAR of September 2007) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance indolylbutyric acid 14Sep2010 2010 doi:10.2903/j.efsa.2010.1720
+Indolylbutyric acid 205-101-5 133-32-4 single chemical entity Component is identical to the substance Indolylbutyric acid 205-101-5 133-32-4 4-(1H-indol-3-yl)butanoic acid Not in list C12H13NO2 OC(=O)CCCc1c[nH]c2ccccc12 InChI=1/C12H13NO2/c14-12(15)7-3-4-9-8-13-11-6-2-1-5-10(9)11/h1-2,5-6,8,13H,3-4,7H2,(H,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Indolylbutiric acid (Revised DAR of September 2007) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance indolylbutyric acid 14Sep2010 2010 doi:10.2903/j.efsa.2010.1720
+Indolylbutyric acid 205-101-5 133-32-4 single chemical entity Component is identical to the substance Indolylbutyric acid 205-101-5 133-32-4 4-(1H-indol-3-yl)butanoic acid Not in list C12H13NO2 OC(=O)CCCc1c[nH]c2ccccc12 InChI=1/C12H13NO2/c14-12(15)7-3-4-9-8-13-11-6-2-1-5-10(9)11/h1-2,5-6,8,13H,3-4,7H2,(H,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Indolylbutiric acid (Revised DAR of September 2007) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance indolylbutyric acid 14Sep2010 2010 doi:10.2903/j.efsa.2010.1720
+Indolylbutyric acid 205-101-5 133-32-4 single chemical entity Component is identical to the substance Indolylbutyric acid 205-101-5 133-32-4 4-(1H-indol-3-yl)butanoic acid Not in list C12H13NO2 OC(=O)CCCc1c[nH]c2ccccc12 InChI=1/C12H13NO2/c14-12(15)7-3-4-9-8-13-11-6-2-1-5-10(9)11/h1-2,5-6,8,13H,3-4,7H2,(H,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Indolylbutiric acid (Revised DAR of September 2007) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance indolylbutyric acid 14Sep2010 2010 doi:10.2903/j.efsa.2010.1720
+Indolylbutyric acid 205-101-5 133-32-4 single chemical entity Component is identical to the substance Indolylbutyric acid 205-101-5 133-32-4 4-(1H-indol-3-yl)butanoic acid Not in list C12H13NO2 OC(=O)CCCc1c[nH]c2ccccc12 InChI=1/C12H13NO2/c14-12(15)7-3-4-9-8-13-11-6-2-1-5-10(9)11/h1-2,5-6,8,13H,3-4,7H2,(H,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Indolylbutiric acid (Revised DAR of September 2007) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance indolylbutyric acid 14Sep2010 2010 doi:10.2903/j.efsa.2010.1720
+Indolylbutyric acid 205-101-5 133-32-4 single chemical entity Component is identical to the substance Indolylbutyric acid 205-101-5 133-32-4 4-(1H-indol-3-yl)butanoic acid Not in list C12H13NO2 OC(=O)CCCc1c[nH]c2ccccc12 InChI=1/C12H13NO2/c14-12(15)7-3-4-9-8-13-11-6-2-1-5-10(9)11/h1-2,5-6,8,13H,3-4,7H2,(H,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: France Indolylbutiric acid (Revised DAR of September 2007) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance indolylbutyric acid 14Sep2010 2010 doi:10.2903/j.efsa.2010.1720
+Indolylbutyric acid 205-101-5 133-32-4 single chemical entity Component is identical to the substance Indolylbutyric acid 205-101-5 133-32-4 4-(1H-indol-3-yl)butanoic acid Not in list C12H13NO2 OC(=O)CCCc1c[nH]c2ccccc12 InChI=1/C12H13NO2/c14-12(15)7-3-4-9-8-13-11-6-2-1-5-10(9)11/h1-2,5-6,8,13H,3-4,7H2,(H,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Indolylbutiric acid (Revised DAR of September 2007) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance indolylbutyric acid 14Sep2010 2010 doi:10.2903/j.efsa.2010.1720
+Indolylbutyric acid 205-101-5 133-32-4 single chemical entity Component is identical to the substance Indolylbutyric acid 205-101-5 133-32-4 4-(1H-indol-3-yl)butanoic acid Not in list C12H13NO2 OC(=O)CCCc1c[nH]c2ccccc12 InChI=1/C12H13NO2/c14-12(15)7-3-4-9-8-13-11-6-2-1-5-10(9)11/h1-2,5-6,8,13H,3-4,7H2,(H,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: France Indolylbutiric acid (Revised DAR of September 2007) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance indolylbutyric acid 14Sep2010 2010 doi:10.2903/j.efsa.2010.1720
+Indolylbutyric acid 205-101-5 133-32-4 single chemical entity Component is identical to the substance Indolylbutyric acid 205-101-5 133-32-4 4-(1H-indol-3-yl)butanoic acid Not in list C12H13NO2 OC(=O)CCCc1c[nH]c2ccccc12 InChI=1/C12H13NO2/c14-12(15)7-3-4-9-8-13-11-6-2-1-5-10(9)11/h1-2,5-6,8,13H,3-4,7H2,(H,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Indolylbutiric acid (Revised DAR of September 2007) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance indolylbutyric acid 14Sep2010 2010 doi:10.2903/j.efsa.2010.1720
+Indolylbutyric acid 205-101-5 133-32-4 single chemical entity Component is identical to the substance Indolylbutyric acid 205-101-5 133-32-4 4-(1H-indol-3-yl)butanoic acid Not in list C12H13NO2 OC(=O)CCCc1c[nH]c2ccccc12 InChI=1/C12H13NO2/c14-12(15)7-3-4-9-8-13-11-6-2-1-5-10(9)11/h1-2,5-6,8,13H,3-4,7H2,(H,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Indolylbutiric acid (Revised DAR of September 2007) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance indolylbutyric acid 14Sep2010 2010 doi:10.2903/j.efsa.2010.1720
+Indolylbutyric acid 205-101-5 133-32-4 single chemical entity Component is identical to the substance Indolylbutyric acid 205-101-5 133-32-4 4-(1H-indol-3-yl)butanoic acid Not in list C12H13NO2 OC(=O)CCCc1c[nH]c2ccccc12 InChI=1/C12H13NO2/c14-12(15)7-3-4-9-8-13-11-6-2-1-5-10(9)11/h1-2,5-6,8,13H,3-4,7H2,(H,14,15) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: France Indolylbutiric acid (Revised DAR of September 2007) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance indolylbutyric acid 14Sep2010 2010 doi:10.2903/j.efsa.2010.1720
+Indolylbutyric acid 205-101-5 133-32-4 single chemical entity Component is identical to the substance Indolylbutyric acid 205-101-5 133-32-4 4-(1H-indol-3-yl)butanoic acid Not in list C12H13NO2 OC(=O)CCCc1c[nH]c2ccccc12 InChI=1/C12H13NO2/c14-12(15)7-3-4-9-8-13-11-6-2-1-5-10(9)11/h1-2,5-6,8,13H,3-4,7H2,(H,14,15) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: France Indolylbutiric acid (Revised DAR of September 2007) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance indolylbutyric acid 14Sep2010 2010 doi:10.2903/j.efsa.2010.1720
+2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 single chemical entity Component is identical to the substance 2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane Metaldehyde C8H16O4 CC1OC(C)OC(C)OC(C)O1 InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Austria Metaldehyde 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde 22Oct2010 2010 doi:10.2903/j.efsa.2010.1856
+2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 single chemical entity Component is identical to the substance 2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane Metaldehyde C8H16O4 CC1OC(C)OC(C)OC(C)O1 InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: Austria Metaldehyde 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde 22Oct2010 2010 doi:10.2903/j.efsa.2010.1856
+2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 single chemical entity Component is identical to the substance 2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane Metaldehyde C8H16O4 CC1OC(C)OC(C)OC(C)O1 InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: Austria Metaldehyde 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde 22Oct2010 2010 doi:10.2903/j.efsa.2010.1856
+2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 single chemical entity Component is identical to the substance 2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane Metaldehyde C8H16O4 CC1OC(C)OC(C)OC(C)O1 InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Austria Metaldehyde 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde 22Oct2010 2010 doi:10.2903/j.efsa.2010.1856
+2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 single chemical entity Component is identical to the substance 2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane Metaldehyde C8H16O4 CC1OC(C)OC(C)OC(C)O1 InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Austria Metaldehyde 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde 22Oct2010 2010 doi:10.2903/j.efsa.2010.1856
+2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 single chemical entity Component is identical to the substance 2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane Metaldehyde C8H16O4 CC1OC(C)OC(C)OC(C)O1 InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Austria Metaldehyde 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde 22Oct2010 2010 doi:10.2903/j.efsa.2010.1856
+2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 single chemical entity Component is identical to the substance 2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane Metaldehyde C8H16O4 CC1OC(C)OC(C)OC(C)O1 InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Austria Metaldehyde 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde 22Oct2010 2010 doi:10.2903/j.efsa.2010.1856
+2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 single chemical entity Component is identical to the substance 2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane Metaldehyde C8H16O4 CC1OC(C)OC(C)OC(C)O1 InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Austria Metaldehyde 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde 22Oct2010 2010 doi:10.2903/j.efsa.2010.1856
+2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 single chemical entity Component is identical to the substance 2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane Metaldehyde C8H16O4 CC1OC(C)OC(C)OC(C)O1 InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Austria Metaldehyde 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde 22Oct2010 2010 doi:10.2903/j.efsa.2010.1856
+2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 single chemical entity Component is identical to the substance 2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane Metaldehyde C8H16O4 CC1OC(C)OC(C)OC(C)O1 InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Austria Metaldehyde 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde 22Oct2010 2010 doi:10.2903/j.efsa.2010.1856
+2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 single chemical entity Component is identical to the substance 2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane Metaldehyde C8H16O4 CC1OC(C)OC(C)OC(C)O1 InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Austria Metaldehyde 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde 22Oct2010 2010 doi:10.2903/j.efsa.2010.1856
+2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 single chemical entity Component is identical to the substance 2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane Metaldehyde C8H16O4 CC1OC(C)OC(C)OC(C)O1 InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: Austria Metaldehyde 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde 22Oct2010 2010 doi:10.2903/j.efsa.2010.1856
+2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 single chemical entity Component is identical to the substance 2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane Metaldehyde C8H16O4 CC1OC(C)OC(C)OC(C)O1 InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Austria Metaldehyde 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde 22Oct2010 2010 doi:10.2903/j.efsa.2010.1856
+2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 single chemical entity Component is identical to the substance 2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane Metaldehyde C8H16O4 CC1OC(C)OC(C)OC(C)O1 InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Austria Metaldehyde 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde 22Oct2010 2010 doi:10.2903/j.efsa.2010.1856
+2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 single chemical entity Component is identical to the substance 2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane Metaldehyde C8H16O4 CC1OC(C)OC(C)OC(C)O1 InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Austria Metaldehyde 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde 22Oct2010 2010 doi:10.2903/j.efsa.2010.1856
+2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 single chemical entity Component is identical to the substance 2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane Metaldehyde C8H16O4 CC1OC(C)OC(C)OC(C)O1 InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Austria Metaldehyde 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde 22Oct2010 2010 doi:10.2903/j.efsa.2010.1856
+2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 single chemical entity Component is identical to the substance 2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane Metaldehyde C8H16O4 CC1OC(C)OC(C)OC(C)O1 InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Austria Metaldehyde 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde 22Oct2010 2010 doi:10.2903/j.efsa.2010.1856
+2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 single chemical entity Component is identical to the substance 2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane Metaldehyde C8H16O4 CC1OC(C)OC(C)OC(C)O1 InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Austria Metaldehyde 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde 22Oct2010 2010 doi:10.2903/j.efsa.2010.1856
+2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 single chemical entity Component is identical to the substance 2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane Metaldehyde C8H16O4 CC1OC(C)OC(C)OC(C)O1 InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Austria Metaldehyde 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde 22Oct2010 2010 doi:10.2903/j.efsa.2010.1856
+2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 single chemical entity Component is identical to the substance 2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane Metaldehyde C8H16O4 CC1OC(C)OC(C)OC(C)O1 InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: Austria Metaldehyde 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde 22Oct2010 2010 doi:10.2903/j.efsa.2010.1856
+2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 single chemical entity Component is identical to the substance 2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane Metaldehyde C8H16O4 CC1OC(C)OC(C)OC(C)O1 InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative no information RMS: Austria Metaldehyde 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde 22Oct2010 2010 doi:10.2903/j.efsa.2010.1856
+2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 single chemical entity Component is identical to the substance 2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane Metaldehyde C8H16O4 CC1OC(C)OC(C)OC(C)O1 InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Negative no information RMS: Austria Metaldehyde 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde 22Oct2010 2010 doi:10.2903/j.efsa.2010.1856
+2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 single chemical entity Component is identical to the substance 2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane Metaldehyde C8H16O4 CC1OC(C)OC(C)OC(C)O1 InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: Austria Metaldehyde 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde 22Oct2010 2010 doi:10.2903/j.efsa.2010.1856
+2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 single chemical entity Component is identical to the substance 2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane Metaldehyde C8H16O4 CC1OC(C)OC(C)OC(C)O1 InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: Austria Metaldehyde 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde 22Oct2010 2010 doi:10.2903/j.efsa.2010.1856
+2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 single chemical entity Component is identical to the substance 2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane Metaldehyde C8H16O4 CC1OC(C)OC(C)OC(C)O1 InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3 organic compound Other Other DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) WP67 Not reported yes without Negative RMS: Austria Metaldehyde 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde 22Oct2010 2010 doi:10.2903/j.efsa.2010.1856
+2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 single chemical entity Component is identical to the substance 2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane Metaldehyde C8H16O4 CC1OC(C)OC(C)OC(C)O1 InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3 organic compound Other Other DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) CM871 Not reported yes without Negative RMS: Austria Metaldehyde 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde 22Oct2010 2010 doi:10.2903/j.efsa.2010.1856
+2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 single chemical entity Component is identical to the substance 2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane Metaldehyde C8H16O4 CC1OC(C)OC(C)OC(C)O1 InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3 organic compound Other Other DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) CM871 Not reported yes with Negative RMS: Austria Metaldehyde 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde 22Oct2010 2010 doi:10.2903/j.efsa.2010.1856
+2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 single chemical entity Component is identical to the substance 2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane Metaldehyde C8H16O4 CC1OC(C)OC(C)OC(C)O1 InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3 organic compound Other Other DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) WP67 Not reported yes with Negative RMS: Austria Metaldehyde 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde 22Oct2010 2010 doi:10.2903/j.efsa.2010.1856
+2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 single chemical entity Component is identical to the substance 2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane Metaldehyde C8H16O4 CC1OC(C)OC(C)OC(C)O1 InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3 organic compound Other Other DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) WP2 Not reported yes without Negative RMS: Austria Metaldehyde 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde 22Oct2010 2010 doi:10.2903/j.efsa.2010.1856
+2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 single chemical entity Component is identical to the substance 2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane Metaldehyde C8H16O4 CC1OC(C)OC(C)OC(C)O1 InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3 organic compound Other Other DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) WP2 Not reported yes with Negative RMS: Austria Metaldehyde 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde 22Oct2010 2010 doi:10.2903/j.efsa.2010.1856
+2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 single chemical entity Component is identical to the substance 2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane Metaldehyde C8H16O4 CC1OC(C)OC(C)OC(C)O1 InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) ICR 10 Male/Female oral: gavage 72.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Austria Metaldehyde 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde 22Oct2010 2010 doi:10.2903/j.efsa.2010.1856
+2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 single chemical entity Component is identical to the substance 2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane Metaldehyde C8H16O4 CC1OC(C)OC(C)OC(C)O1 InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) ICR 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Austria Metaldehyde 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde 22Oct2010 2010 doi:10.2903/j.efsa.2010.1856
+2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 single chemical entity Component is identical to the substance 2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane 203-600-2 108-62-3 2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane Metaldehyde C8H16O4 CC1OC(C)OC(C)OC(C)O1 InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) ICR 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Austria Metaldehyde 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde 22Oct2010 2010 doi:10.2903/j.efsa.2010.1856
+Metobromuron 221-301-5 3060-89-7 single chemical entity Component is identical to the substance Metobromuron 221-301-5 3060-89-7 3-(4-bromophenyl)-1-methoxy-1-methylurea Metobromuron C9H11BrN2O2 CN(C(=O)NC1=CC=C(C=C1)Br)OC InChI=1S/C9H11BrN2O2/c1-12(14-2)9(13)11-8-5-3-7(10)4-6-8/h3-6H,1-2H3,(H,11,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Metobromuron 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron. 04Feb2014 2014 doi:10.2903/j.efsa.2014.3541
+Metobromuron 221-301-5 3060-89-7 single chemical entity Component is identical to the substance Metobromuron 221-301-5 3060-89-7 3-(4-bromophenyl)-1-methoxy-1-methylurea Metobromuron C9H11BrN2O2 CN(C(=O)NC1=CC=C(C=C1)Br)OC InChI=1S/C9H11BrN2O2/c1-12(14-2)9(13)11-8-5-3-7(10)4-6-8/h3-6H,1-2H3,(H,11,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Metobromuron 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron. 04Feb2014 2014 doi:10.2903/j.efsa.2014.3541
+Metobromuron 221-301-5 3060-89-7 single chemical entity Component is identical to the substance Metobromuron 221-301-5 3060-89-7 3-(4-bromophenyl)-1-methoxy-1-methylurea Metobromuron C9H11BrN2O2 CN(C(=O)NC1=CC=C(C=C1)Br)OC InChI=1S/C9H11BrN2O2/c1-12(14-2)9(13)11-8-5-3-7(10)4-6-8/h3-6H,1-2H3,(H,11,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Metobromuron 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron. 04Feb2014 2014 doi:10.2903/j.efsa.2014.3541
+Metobromuron 221-301-5 3060-89-7 single chemical entity Component is identical to the substance Metobromuron 221-301-5 3060-89-7 3-(4-bromophenyl)-1-methoxy-1-methylurea Metobromuron C9H11BrN2O2 CN(C(=O)NC1=CC=C(C=C1)Br)OC InChI=1S/C9H11BrN2O2/c1-12(14-2)9(13)11-8-5-3-7(10)4-6-8/h3-6H,1-2H3,(H,11,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: France Metobromuron 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron. 04Feb2014 2014 doi:10.2903/j.efsa.2014.3541
+Metobromuron 221-301-5 3060-89-7 single chemical entity Component is identical to the substance Metobromuron 221-301-5 3060-89-7 3-(4-bromophenyl)-1-methoxy-1-methylurea Metobromuron C9H11BrN2O2 CN(C(=O)NC1=CC=C(C=C1)Br)OC InChI=1S/C9H11BrN2O2/c1-12(14-2)9(13)11-8-5-3-7(10)4-6-8/h3-6H,1-2H3,(H,11,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: France Metobromuron 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron. 04Feb2014 2014 doi:10.2903/j.efsa.2014.3541
+Metobromuron 221-301-5 3060-89-7 single chemical entity Component is identical to the substance Metobromuron 221-301-5 3060-89-7 3-(4-bromophenyl)-1-methoxy-1-methylurea Metobromuron C9H11BrN2O2 CN(C(=O)NC1=CC=C(C=C1)Br)OC InChI=1S/C9H11BrN2O2/c1-12(14-2)9(13)11-8-5-3-7(10)4-6-8/h3-6H,1-2H3,(H,11,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Metobromuron 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron. 04Feb2014 2014 doi:10.2903/j.efsa.2014.3541
+Metobromuron 221-301-5 3060-89-7 single chemical entity Component is identical to the substance Metobromuron 221-301-5 3060-89-7 3-(4-bromophenyl)-1-methoxy-1-methylurea Metobromuron C9H11BrN2O2 CN(C(=O)NC1=CC=C(C=C1)Br)OC InChI=1S/C9H11BrN2O2/c1-12(14-2)9(13)11-8-5-3-7(10)4-6-8/h3-6H,1-2H3,(H,11,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Metobromuron 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron. 04Feb2014 2014 doi:10.2903/j.efsa.2014.3541
+Metobromuron 221-301-5 3060-89-7 single chemical entity Component is identical to the substance Metobromuron 221-301-5 3060-89-7 3-(4-bromophenyl)-1-methoxy-1-methylurea Metobromuron C9H11BrN2O2 CN(C(=O)NC1=CC=C(C=C1)Br)OC InChI=1S/C9H11BrN2O2/c1-12(14-2)9(13)11-8-5-3-7(10)4-6-8/h3-6H,1-2H3,(H,11,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Metobromuron 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron. 04Feb2014 2014 doi:10.2903/j.efsa.2014.3541
+Metobromuron 221-301-5 3060-89-7 single chemical entity Component is identical to the substance Metobromuron 221-301-5 3060-89-7 3-(4-bromophenyl)-1-methoxy-1-methylurea Metobromuron C9H11BrN2O2 CN(C(=O)NC1=CC=C(C=C1)Br)OC InChI=1S/C9H11BrN2O2/c1-12(14-2)9(13)11-8-5-3-7(10)4-6-8/h3-6H,1-2H3,(H,11,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Metobromuron 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron. 04Feb2014 2014 doi:10.2903/j.efsa.2014.3541
+Metobromuron 221-301-5 3060-89-7 single chemical entity Component is identical to the substance Metobromuron 221-301-5 3060-89-7 3-(4-bromophenyl)-1-methoxy-1-methylurea Metobromuron C9H11BrN2O2 CN(C(=O)NC1=CC=C(C=C1)Br)OC InChI=1S/C9H11BrN2O2/c1-12(14-2)9(13)11-8-5-3-7(10)4-6-8/h3-6H,1-2H3,(H,11,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Metobromuron 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron. 04Feb2014 2014 doi:10.2903/j.efsa.2014.3541
+Metobromuron 221-301-5 3060-89-7 single chemical entity Component is identical to the substance Metobromuron 221-301-5 3060-89-7 3-(4-bromophenyl)-1-methoxy-1-methylurea Metobromuron C9H11BrN2O2 CN(C(=O)NC1=CC=C(C=C1)Br)OC InChI=1S/C9H11BrN2O2/c1-12(14-2)9(13)11-8-5-3-7(10)4-6-8/h3-6H,1-2H3,(H,11,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative large colonies RMS: France Metobromuron 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron. 04Feb2014 2014 doi:10.2903/j.efsa.2014.3541
+Metobromuron 221-301-5 3060-89-7 single chemical entity Component is identical to the substance Metobromuron 221-301-5 3060-89-7 3-(4-bromophenyl)-1-methoxy-1-methylurea Metobromuron C9H11BrN2O2 CN(C(=O)NC1=CC=C(C=C1)Br)OC InChI=1S/C9H11BrN2O2/c1-12(14-2)9(13)11-8-5-3-7(10)4-6-8/h3-6H,1-2H3,(H,11,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative large colonies RMS: France Metobromuron 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron. 04Feb2014 2014 doi:10.2903/j.efsa.2014.3541
+Metobromuron 221-301-5 3060-89-7 single chemical entity Component is identical to the substance Metobromuron 221-301-5 3060-89-7 3-(4-bromophenyl)-1-methoxy-1-methylurea Metobromuron C9H11BrN2O2 CN(C(=O)NC1=CC=C(C=C1)Br)OC InChI=1S/C9H11BrN2O2/c1-12(14-2)9(13)11-8-5-3-7(10)4-6-8/h3-6H,1-2H3,(H,11,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative small colonies RMS: France Metobromuron 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron. 04Feb2014 2014 doi:10.2903/j.efsa.2014.3541
+Metobromuron 221-301-5 3060-89-7 single chemical entity Component is identical to the substance Metobromuron 221-301-5 3060-89-7 3-(4-bromophenyl)-1-methoxy-1-methylurea Metobromuron C9H11BrN2O2 CN(C(=O)NC1=CC=C(C=C1)Br)OC InChI=1S/C9H11BrN2O2/c1-12(14-2)9(13)11-8-5-3-7(10)4-6-8/h3-6H,1-2H3,(H,11,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative small colonies RMS: France Metobromuron 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron. 04Feb2014 2014 doi:10.2903/j.efsa.2014.3541
+Metobromuron 221-301-5 3060-89-7 single chemical entity Component is identical to the substance Metobromuron 221-301-5 3060-89-7 3-(4-bromophenyl)-1-methoxy-1-methylurea Metobromuron C9H11BrN2O2 CN(C(=O)NC1=CC=C(C=C1)Br)OC InChI=1S/C9H11BrN2O2/c1-12(14-2)9(13)11-8-5-3-7(10)4-6-8/h3-6H,1-2H3,(H,11,13) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: France Metobromuron 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron. 04Feb2014 2014 doi:10.2903/j.efsa.2014.3541
+Metobromuron 221-301-5 3060-89-7 single chemical entity Component is identical to the substance Metobromuron 221-301-5 3060-89-7 3-(4-bromophenyl)-1-methoxy-1-methylurea Metobromuron C9H11BrN2O2 CN(C(=O)NC1=CC=C(C=C1)Br)OC InChI=1S/C9H11BrN2O2/c1-12(14-2)9(13)11-8-5-3-7(10)4-6-8/h3-6H,1-2H3,(H,11,13) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: France Metobromuron 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron. 04Feb2014 2014 doi:10.2903/j.efsa.2014.3541
+Metobromuron 221-301-5 3060-89-7 single chemical entity Component is identical to the substance Metobromuron 221-301-5 3060-89-7 3-(4-bromophenyl)-1-methoxy-1-methylurea Metobromuron C9H11BrN2O2 CN(C(=O)NC1=CC=C(C=C1)Br)OC InChI=1S/C9H11BrN2O2/c1-12(14-2)9(13)11-8-5-3-7(10)4-6-8/h3-6H,1-2H3,(H,11,13) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable Rat (as animal) Crj:CD(SD) 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: France Metobromuron 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron. 04Feb2014 2014 doi:10.2903/j.efsa.2014.3541
+Metobromuron 221-301-5 3060-89-7 single chemical entity Component is identical to the substance Metobromuron 221-301-5 3060-89-7 3-(4-bromophenyl)-1-methoxy-1-methylurea Metobromuron C9H11BrN2O2 CN(C(=O)NC1=CC=C(C=C1)Br)OC InChI=1S/C9H11BrN2O2/c1-12(14-2)9(13)11-8-5-3-7(10)4-6-8/h3-6H,1-2H3,(H,11,13) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable Rat (as animal) Crj:CD(SD) 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: France Metobromuron 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron. 04Feb2014 2014 doi:10.2903/j.efsa.2014.3541
+Picolinafen 604-030-0 137641-05-5 single chemical entity Component is identical to the substance Picolinafen 604-030-0 137641-05-5 N-(4-fluorophenyl)-6-[3(trifluoromethyl)phenoxy]pyridine-2carboxamide Picolinafen C19H12F4N2O2 C1=CC(=CC(=C1)OC2=CC=CC(=N2)C(=O)NC3=CC=C(C=C3)F)C(F)(F)F InChI=1S/C19H12F4N2O2/c20-13-7-9-14(10-8-13)24-18(26)16-5-2-6-17(25-16)27-15-4-1-3-12(11-15)19(21,22)23/h1-11H,(H,24,26) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Latvia Picolinafen 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance picolinafen 04Nov2015 2015 doi:10.2903/j.efsa.2015.4279
+Picolinafen 604-030-0 137641-05-5 single chemical entity Component is identical to the substance Picolinafen 604-030-0 137641-05-5 N-(4-fluorophenyl)-6-[3(trifluoromethyl)phenoxy]pyridine-2carboxamide Picolinafen C19H12F4N2O2 C1=CC(=CC(=C1)OC2=CC=CC(=N2)C(=O)NC3=CC=C(C=C3)F)C(F)(F)F InChI=1S/C19H12F4N2O2/c20-13-7-9-14(10-8-13)24-18(26)16-5-2-6-17(25-16)27-15-4-1-3-12(11-15)19(21,22)23/h1-11H,(H,24,26) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Latvia Picolinafen 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance picolinafen 04Nov2015 2015 doi:10.2903/j.efsa.2015.4279
+Picolinafen 604-030-0 137641-05-5 single chemical entity Component is identical to the substance Picolinafen 604-030-0 137641-05-5 N-(4-fluorophenyl)-6-[3(trifluoromethyl)phenoxy]pyridine-2carboxamide Picolinafen C19H12F4N2O2 C1=CC(=CC(=C1)OC2=CC=CC(=N2)C(=O)NC3=CC=C(C=C3)F)C(F)(F)F InChI=1S/C19H12F4N2O2/c20-13-7-9-14(10-8-13)24-18(26)16-5-2-6-17(25-16)27-15-4-1-3-12(11-15)19(21,22)23/h1-11H,(H,24,26) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Latvia Picolinafen 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance picolinafen 04Nov2015 2015 doi:10.2903/j.efsa.2015.4279
+Picolinafen 604-030-0 137641-05-5 single chemical entity Component is identical to the substance Picolinafen 604-030-0 137641-05-5 N-(4-fluorophenyl)-6-[3(trifluoromethyl)phenoxy]pyridine-2carboxamide Picolinafen C19H12F4N2O2 C1=CC(=CC(=C1)OC2=CC=CC(=N2)C(=O)NC3=CC=C(C=C3)F)C(F)(F)F InChI=1S/C19H12F4N2O2/c20-13-7-9-14(10-8-13)24-18(26)16-5-2-6-17(25-16)27-15-4-1-3-12(11-15)19(21,22)23/h1-11H,(H,24,26) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Latvia Picolinafen 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance picolinafen 04Nov2015 2015 doi:10.2903/j.efsa.2015.4279
+Picolinafen 604-030-0 137641-05-5 single chemical entity Component is identical to the substance Picolinafen 604-030-0 137641-05-5 N-(4-fluorophenyl)-6-[3(trifluoromethyl)phenoxy]pyridine-2carboxamide Picolinafen C19H12F4N2O2 C1=CC(=CC(=C1)OC2=CC=CC(=N2)C(=O)NC3=CC=C(C=C3)F)C(F)(F)F InChI=1S/C19H12F4N2O2/c20-13-7-9-14(10-8-13)24-18(26)16-5-2-6-17(25-16)27-15-4-1-3-12(11-15)19(21,22)23/h1-11H,(H,24,26) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Latvia Picolinafen 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance picolinafen 04Nov2015 2015 doi:10.2903/j.efsa.2015.4279
+Picolinafen 604-030-0 137641-05-5 single chemical entity Component is identical to the substance Picolinafen 604-030-0 137641-05-5 N-(4-fluorophenyl)-6-[3(trifluoromethyl)phenoxy]pyridine-2carboxamide Picolinafen C19H12F4N2O2 C1=CC(=CC(=C1)OC2=CC=CC(=N2)C(=O)NC3=CC=C(C=C3)F)C(F)(F)F InChI=1S/C19H12F4N2O2/c20-13-7-9-14(10-8-13)24-18(26)16-5-2-6-17(25-16)27-15-4-1-3-12(11-15)19(21,22)23/h1-11H,(H,24,26) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Latvia Picolinafen 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance picolinafen 04Nov2015 2015 doi:10.2903/j.efsa.2015.4279
+Picolinafen 604-030-0 137641-05-5 single chemical entity Component is identical to the substance Picolinafen 604-030-0 137641-05-5 N-(4-fluorophenyl)-6-[3(trifluoromethyl)phenoxy]pyridine-2carboxamide Picolinafen C19H12F4N2O2 C1=CC(=CC(=C1)OC2=CC=CC(=N2)C(=O)NC3=CC=C(C=C3)F)C(F)(F)F InChI=1S/C19H12F4N2O2/c20-13-7-9-14(10-8-13)24-18(26)16-5-2-6-17(25-16)27-15-4-1-3-12(11-15)19(21,22)23/h1-11H,(H,24,26) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Latvia Picolinafen 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance picolinafen 04Nov2015 2015 doi:10.2903/j.efsa.2015.4279
+Picolinafen 604-030-0 137641-05-5 single chemical entity Component is identical to the substance Picolinafen 604-030-0 137641-05-5 N-(4-fluorophenyl)-6-[3(trifluoromethyl)phenoxy]pyridine-2carboxamide Picolinafen C19H12F4N2O2 C1=CC(=CC(=C1)OC2=CC=CC(=N2)C(=O)NC3=CC=C(C=C3)F)C(F)(F)F InChI=1S/C19H12F4N2O2/c20-13-7-9-14(10-8-13)24-18(26)16-5-2-6-17(25-16)27-15-4-1-3-12(11-15)19(21,22)23/h1-11H,(H,24,26) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Latvia Picolinafen 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance picolinafen 04Nov2015 2015 doi:10.2903/j.efsa.2015.4279
+Picolinafen 604-030-0 137641-05-5 single chemical entity Component is identical to the substance Picolinafen 604-030-0 137641-05-5 N-(4-fluorophenyl)-6-[3(trifluoromethyl)phenoxy]pyridine-2carboxamide Picolinafen C19H12F4N2O2 C1=CC(=CC(=C1)OC2=CC=CC(=N2)C(=O)NC3=CC=C(C=C3)F)C(F)(F)F InChI=1S/C19H12F4N2O2/c20-13-7-9-14(10-8-13)24-18(26)16-5-2-6-17(25-16)27-15-4-1-3-12(11-15)19(21,22)23/h1-11H,(H,24,26) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Latvia Picolinafen 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance picolinafen 04Nov2015 2015 doi:10.2903/j.efsa.2015.4279
+Picolinafen 604-030-0 137641-05-5 single chemical entity Component is identical to the substance Picolinafen 604-030-0 137641-05-5 N-(4-fluorophenyl)-6-[3(trifluoromethyl)phenoxy]pyridine-2carboxamide Picolinafen C19H12F4N2O2 C1=CC(=CC(=C1)OC2=CC=CC(=N2)C(=O)NC3=CC=C(C=C3)F)C(F)(F)F InChI=1S/C19H12F4N2O2/c20-13-7-9-14(10-8-13)24-18(26)16-5-2-6-17(25-16)27-15-4-1-3-12(11-15)19(21,22)23/h1-11H,(H,24,26) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Latvia Picolinafen 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance picolinafen 04Nov2015 2015 doi:10.2903/j.efsa.2015.4279
+Picolinafen 604-030-0 137641-05-5 single chemical entity Component is identical to the substance Picolinafen 604-030-0 137641-05-5 N-(4-fluorophenyl)-6-[3(trifluoromethyl)phenoxy]pyridine-2carboxamide Picolinafen C19H12F4N2O2 C1=CC(=CC(=C1)OC2=CC=CC(=N2)C(=O)NC3=CC=C(C=C3)F)C(F)(F)F InChI=1S/C19H12F4N2O2/c20-13-7-9-14(10-8-13)24-18(26)16-5-2-6-17(25-16)27-15-4-1-3-12(11-15)19(21,22)23/h1-11H,(H,24,26) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Latvia Picolinafen 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance picolinafen 04Nov2015 2015 doi:10.2903/j.efsa.2015.4279
+Picolinafen 604-030-0 137641-05-5 single chemical entity Component is identical to the substance Picolinafen 604-030-0 137641-05-5 N-(4-fluorophenyl)-6-[3(trifluoromethyl)phenoxy]pyridine-2carboxamide Picolinafen C19H12F4N2O2 C1=CC(=CC(=C1)OC2=CC=CC(=N2)C(=O)NC3=CC=C(C=C3)F)C(F)(F)F InChI=1S/C19H12F4N2O2/c20-13-7-9-14(10-8-13)24-18(26)16-5-2-6-17(25-16)27-15-4-1-3-12(11-15)19(21,22)23/h1-11H,(H,24,26) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Latvia Picolinafen 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance picolinafen 04Nov2015 2015 doi:10.2903/j.efsa.2015.4279
+Picolinafen 604-030-0 137641-05-5 single chemical entity Component is identical to the substance Picolinafen 604-030-0 137641-05-5 N-(4-fluorophenyl)-6-[3(trifluoromethyl)phenoxy]pyridine-2carboxamide Picolinafen C19H12F4N2O2 C1=CC(=CC(=C1)OC2=CC=CC(=N2)C(=O)NC3=CC=C(C=C3)F)C(F)(F)F InChI=1S/C19H12F4N2O2/c20-13-7-9-14(10-8-13)24-18(26)16-5-2-6-17(25-16)27-15-4-1-3-12(11-15)19(21,22)23/h1-11H,(H,24,26) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Latvia Picolinafen 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance picolinafen 04Nov2015 2015 doi:10.2903/j.efsa.2015.4279
+Picolinafen 604-030-0 137641-05-5 single chemical entity Component is identical to the substance Picolinafen 604-030-0 137641-05-5 N-(4-fluorophenyl)-6-[3(trifluoromethyl)phenoxy]pyridine-2carboxamide Picolinafen C19H12F4N2O2 C1=CC(=CC(=C1)OC2=CC=CC(=N2)C(=O)NC3=CC=C(C=C3)F)C(F)(F)F InChI=1S/C19H12F4N2O2/c20-13-7-9-14(10-8-13)24-18(26)16-5-2-6-17(25-16)27-15-4-1-3-12(11-15)19(21,22)23/h1-11H,(H,24,26) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Latvia Picolinafen 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance picolinafen 04Nov2015 2015 doi:10.2903/j.efsa.2015.4279
+Picolinafen 604-030-0 137641-05-5 single chemical entity Component is identical to the substance Picolinafen 604-030-0 137641-05-5 N-(4-fluorophenyl)-6-[3(trifluoromethyl)phenoxy]pyridine-2carboxamide Picolinafen C19H12F4N2O2 C1=CC(=CC(=C1)OC2=CC=CC(=N2)C(=O)NC3=CC=C(C=C3)F)C(F)(F)F InChI=1S/C19H12F4N2O2/c20-13-7-9-14(10-8-13)24-18(26)16-5-2-6-17(25-16)27-15-4-1-3-12(11-15)19(21,22)23/h1-11H,(H,24,26) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Latvia Picolinafen 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance picolinafen 04Nov2015 2015 doi:10.2903/j.efsa.2015.4279
+Picolinafen 604-030-0 137641-05-5 single chemical entity Component is identical to the substance Picolinafen 604-030-0 137641-05-5 N-(4-fluorophenyl)-6-[3(trifluoromethyl)phenoxy]pyridine-2carboxamide Picolinafen C19H12F4N2O2 C1=CC(=CC(=C1)OC2=CC=CC(=N2)C(=O)NC3=CC=C(C=C3)F)C(F)(F)F InChI=1S/C19H12F4N2O2/c20-13-7-9-14(10-8-13)24-18(26)16-5-2-6-17(25-16)27-15-4-1-3-12(11-15)19(21,22)23/h1-11H,(H,24,26) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Latvia Picolinafen 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance picolinafen 04Nov2015 2015 doi:10.2903/j.efsa.2015.4279
+Picolinafen 604-030-0 137641-05-5 single chemical entity Component is identical to the substance Picolinafen 604-030-0 137641-05-5 N-(4-fluorophenyl)-6-[3(trifluoromethyl)phenoxy]pyridine-2carboxamide Picolinafen C19H12F4N2O2 C1=CC(=CC(=C1)OC2=CC=CC(=N2)C(=O)NC3=CC=C(C=C3)F)C(F)(F)F InChI=1S/C19H12F4N2O2/c20-13-7-9-14(10-8-13)24-18(26)16-5-2-6-17(25-16)27-15-4-1-3-12(11-15)19(21,22)23/h1-11H,(H,24,26) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 6 Male oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Germany - CoRMS: Latvia Picolinafen 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance picolinafen 04Nov2015 2015 doi:10.2903/j.efsa.2015.4279
+Picolinafen 604-030-0 137641-05-5 single chemical entity Component is identical to the substance Picolinafen 604-030-0 137641-05-5 N-(4-fluorophenyl)-6-[3(trifluoromethyl)phenoxy]pyridine-2carboxamide Picolinafen C19H12F4N2O2 C1=CC(=CC(=C1)OC2=CC=CC(=N2)C(=O)NC3=CC=C(C=C3)F)C(F)(F)F InChI=1S/C19H12F4N2O2/c20-13-7-9-14(10-8-13)24-18(26)16-5-2-6-17(25-16)27-15-4-1-3-12(11-15)19(21,22)23/h1-11H,(H,24,26) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 6 Male oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Germany - CoRMS: Latvia Picolinafen 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance picolinafen 04Nov2015 2015 doi:10.2903/j.efsa.2015.4279
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Positive RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Positive RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Positive RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Picloram 217-636-1 1918-02-1 single chemical entity Component is identical to the substance Picloram 217-636-1 1918-02-1 4-amino-3,5,6-trichloropyridine-2-carboxylic acid Picloram C6H3Cl3N2O2 C1(=C(C(=NC(=C1Cl)Cl)C(=O)O)Cl)N InChI=1S/C6H3Cl3N2O2/c7-1-3(10)2(8)5(9)11-4(1)6(12)13/h(H2,10,11)(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: The United Kingdom Picloram 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance picloram 03Dec2009 2009 doi:10.2903/j.efsa.2009.1390
+Picloram 217-636-1 1918-02-1 single chemical entity Component is identical to the substance Picloram 217-636-1 1918-02-1 4-amino-3,5,6-trichloropyridine-2-carboxylic acid Picloram C6H3Cl3N2O2 C1(=C(C(=NC(=C1Cl)Cl)C(=O)O)Cl)N InChI=1S/C6H3Cl3N2O2/c7-1-3(10)2(8)5(9)11-4(1)6(12)13/h(H2,10,11)(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: The United Kingdom Picloram 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance picloram 03Dec2009 2009 doi:10.2903/j.efsa.2009.1390
+Picloram 217-636-1 1918-02-1 single chemical entity Component is identical to the substance Picloram 217-636-1 1918-02-1 4-amino-3,5,6-trichloropyridine-2-carboxylic acid Picloram C6H3Cl3N2O2 C1(=C(C(=NC(=C1Cl)Cl)C(=O)O)Cl)N InChI=1S/C6H3Cl3N2O2/c7-1-3(10)2(8)5(9)11-4(1)6(12)13/h(H2,10,11)(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: The United Kingdom Picloram 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance picloram 03Dec2009 2009 doi:10.2903/j.efsa.2009.1390
+Picloram 217-636-1 1918-02-1 single chemical entity Component is identical to the substance Picloram 217-636-1 1918-02-1 4-amino-3,5,6-trichloropyridine-2-carboxylic acid Picloram C6H3Cl3N2O2 C1(=C(C(=NC(=C1Cl)Cl)C(=O)O)Cl)N InChI=1S/C6H3Cl3N2O2/c7-1-3(10)2(8)5(9)11-4(1)6(12)13/h(H2,10,11)(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: The United Kingdom Picloram 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance picloram 03Dec2009 2009 doi:10.2903/j.efsa.2009.1390
+Picloram 217-636-1 1918-02-1 single chemical entity Component is identical to the substance Picloram 217-636-1 1918-02-1 4-amino-3,5,6-trichloropyridine-2-carboxylic acid Picloram C6H3Cl3N2O2 C1(=C(C(=NC(=C1Cl)Cl)C(=O)O)Cl)N InChI=1S/C6H3Cl3N2O2/c7-1-3(10)2(8)5(9)11-4(1)6(12)13/h(H2,10,11)(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: The United Kingdom Picloram 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance picloram 03Dec2009 2009 doi:10.2903/j.efsa.2009.1390
+Picloram 217-636-1 1918-02-1 single chemical entity Component is identical to the substance Picloram 217-636-1 1918-02-1 4-amino-3,5,6-trichloropyridine-2-carboxylic acid Picloram C6H3Cl3N2O2 C1(=C(C(=NC(=C1Cl)Cl)C(=O)O)Cl)N InChI=1S/C6H3Cl3N2O2/c7-1-3(10)2(8)5(9)11-4(1)6(12)13/h(H2,10,11)(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: The United Kingdom Picloram 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance picloram 03Dec2009 2009 doi:10.2903/j.efsa.2009.1390
+Picloram 217-636-1 1918-02-1 single chemical entity Component is identical to the substance Picloram 217-636-1 1918-02-1 4-amino-3,5,6-trichloropyridine-2-carboxylic acid Picloram C6H3Cl3N2O2 C1(=C(C(=NC(=C1Cl)Cl)C(=O)O)Cl)N InChI=1S/C6H3Cl3N2O2/c7-1-3(10)2(8)5(9)11-4(1)6(12)13/h(H2,10,11)(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: The United Kingdom Picloram 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance picloram 03Dec2009 2009 doi:10.2903/j.efsa.2009.1390
+Picloram 217-636-1 1918-02-1 single chemical entity Component is identical to the substance Picloram 217-636-1 1918-02-1 4-amino-3,5,6-trichloropyridine-2-carboxylic acid Picloram C6H3Cl3N2O2 C1(=C(C(=NC(=C1Cl)Cl)C(=O)O)Cl)N InChI=1S/C6H3Cl3N2O2/c7-1-3(10)2(8)5(9)11-4(1)6(12)13/h(H2,10,11)(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: The United Kingdom Picloram 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance picloram 03Dec2009 2009 doi:10.2903/j.efsa.2009.1390
+Picloram 217-636-1 1918-02-1 single chemical entity Component is identical to the substance Picloram 217-636-1 1918-02-1 4-amino-3,5,6-trichloropyridine-2-carboxylic acid Picloram C6H3Cl3N2O2 C1(=C(C(=NC(=C1Cl)Cl)C(=O)O)Cl)N InChI=1S/C6H3Cl3N2O2/c7-1-3(10)2(8)5(9)11-4(1)6(12)13/h(H2,10,11)(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Picloram 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance picloram 03Dec2009 2009 doi:10.2903/j.efsa.2009.1390
+Picloram 217-636-1 1918-02-1 single chemical entity Component is identical to the substance Picloram 217-636-1 1918-02-1 4-amino-3,5,6-trichloropyridine-2-carboxylic acid Picloram C6H3Cl3N2O2 C1(=C(C(=NC(=C1Cl)Cl)C(=O)O)Cl)N InChI=1S/C6H3Cl3N2O2/c7-1-3(10)2(8)5(9)11-4(1)6(12)13/h(H2,10,11)(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Picloram 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance picloram 03Dec2009 2009 doi:10.2903/j.efsa.2009.1390
+Picloram 217-636-1 1918-02-1 single chemical entity Component is identical to the substance Picloram 217-636-1 1918-02-1 4-amino-3,5,6-trichloropyridine-2-carboxylic acid Picloram C6H3Cl3N2O2 C1(=C(C(=NC(=C1Cl)Cl)C(=O)O)Cl)N InChI=1S/C6H3Cl3N2O2/c7-1-3(10)2(8)5(9)11-4(1)6(12)13/h(H2,10,11)(H,12,13) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported no data without Negative RMS: The United Kingdom Picloram 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance picloram 03Dec2009 2009 doi:10.2903/j.efsa.2009.1390
+Picloram 217-636-1 1918-02-1 single chemical entity Component is identical to the substance Picloram 217-636-1 1918-02-1 4-amino-3,5,6-trichloropyridine-2-carboxylic acid Picloram C6H3Cl3N2O2 C1(=C(C(=NC(=C1Cl)Cl)C(=O)O)Cl)N InChI=1S/C6H3Cl3N2O2/c7-1-3(10)2(8)5(9)11-4(1)6(12)13/h(H2,10,11)(H,12,13) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent no treatment not applicable Negative indirect-toxicokinetic investigations RMS: The United Kingdom Picloram 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance picloram 03Dec2009 2009 doi:10.2903/j.efsa.2009.1390
+Picloram 217-636-1 1918-02-1 single chemical entity Component is identical to the substance Picloram 217-636-1 1918-02-1 4-amino-3,5,6-trichloropyridine-2-carboxylic acid Picloram C6H3Cl3N2O2 C1(=C(C(=NC(=C1Cl)Cl)C(=O)O)Cl)N InChI=1S/C6H3Cl3N2O2/c7-1-3(10)2(8)5(9)11-4(1)6(12)13/h(H2,10,11)(H,12,13) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent no treatment not applicable Negative indirect-toxicokinetic investigations RMS: The United Kingdom Picloram 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance picloram 03Dec2009 2009 doi:10.2903/j.efsa.2009.1390
+Picloram 217-636-1 1918-02-1 single chemical entity Component is identical to the substance Picloram 217-636-1 1918-02-1 4-amino-3,5,6-trichloropyridine-2-carboxylic acid Picloram C6H3Cl3N2O2 C1(=C(C(=NC(=C1Cl)Cl)C(=O)O)Cl)N InChI=1S/C6H3Cl3N2O2/c7-1-3(10)2(8)5(9)11-4(1)6(12)13/h(H2,10,11)(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: The United Kingdom Picloram (Addendum 1) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance picloram 03Dec2009 2009 doi:10.2903/j.efsa.2009.1390
+Picloram 217-636-1 1918-02-1 single chemical entity Component is identical to the substance Picloram 217-636-1 1918-02-1 4-amino-3,5,6-trichloropyridine-2-carboxylic acid Picloram C6H3Cl3N2O2 C1(=C(C(=NC(=C1Cl)Cl)C(=O)O)Cl)N InChI=1S/C6H3Cl3N2O2/c7-1-3(10)2(8)5(9)11-4(1)6(12)13/h(H2,10,11)(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: The United Kingdom Picloram (Addendum 1) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance picloram 03Dec2009 2009 doi:10.2903/j.efsa.2009.1390
+Picloram 217-636-1 1918-02-1 single chemical entity Component is identical to the substance Picloram 217-636-1 1918-02-1 4-amino-3,5,6-trichloropyridine-2-carboxylic acid Picloram C6H3Cl3N2O2 C1(=C(C(=NC(=C1Cl)Cl)C(=O)O)Cl)N InChI=1S/C6H3Cl3N2O2/c7-1-3(10)2(8)5(9)11-4(1)6(12)13/h(H2,10,11)(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: The United Kingdom Picloram (Addendum 1) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance picloram 03Dec2009 2009 doi:10.2903/j.efsa.2009.1390
+Picloram 217-636-1 1918-02-1 single chemical entity Component is identical to the substance Picloram 217-636-1 1918-02-1 4-amino-3,5,6-trichloropyridine-2-carboxylic acid Picloram C6H3Cl3N2O2 C1(=C(C(=NC(=C1Cl)Cl)C(=O)O)Cl)N InChI=1S/C6H3Cl3N2O2/c7-1-3(10)2(8)5(9)11-4(1)6(12)13/h(H2,10,11)(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: The United Kingdom Picloram (Addendum 1) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance picloram 03Dec2009 2009 doi:10.2903/j.efsa.2009.1390
+Picloram 217-636-1 1918-02-1 single chemical entity Component is identical to the substance Picloram 217-636-1 1918-02-1 4-amino-3,5,6-trichloropyridine-2-carboxylic acid Picloram C6H3Cl3N2O2 C1(=C(C(=NC(=C1Cl)Cl)C(=O)O)Cl)N InChI=1S/C6H3Cl3N2O2/c7-1-3(10)2(8)5(9)11-4(1)6(12)13/h(H2,10,11)(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: The United Kingdom Picloram (Addendum 1) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance picloram 03Dec2009 2009 doi:10.2903/j.efsa.2009.1390
+Picloram 217-636-1 1918-02-1 single chemical entity Component is identical to the substance Picloram 217-636-1 1918-02-1 4-amino-3,5,6-trichloropyridine-2-carboxylic acid Picloram C6H3Cl3N2O2 C1(=C(C(=NC(=C1Cl)Cl)C(=O)O)Cl)N InChI=1S/C6H3Cl3N2O2/c7-1-3(10)2(8)5(9)11-4(1)6(12)13/h(H2,10,11)(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: The United Kingdom Picloram (Addendum 1) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance picloram 03Dec2009 2009 doi:10.2903/j.efsa.2009.1390
+Picloram 217-636-1 1918-02-1 single chemical entity Component is identical to the substance Picloram 217-636-1 1918-02-1 4-amino-3,5,6-trichloropyridine-2-carboxylic acid Picloram C6H3Cl3N2O2 C1(=C(C(=NC(=C1Cl)Cl)C(=O)O)Cl)N InChI=1S/C6H3Cl3N2O2/c7-1-3(10)2(8)5(9)11-4(1)6(12)13/h(H2,10,11)(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: The United Kingdom Picloram (Addendum 1) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance picloram 03Dec2009 2009 doi:10.2903/j.efsa.2009.1390
+Picloram 217-636-1 1918-02-1 single chemical entity Component is identical to the substance Picloram 217-636-1 1918-02-1 4-amino-3,5,6-trichloropyridine-2-carboxylic acid Picloram C6H3Cl3N2O2 C1(=C(C(=NC(=C1Cl)Cl)C(=O)O)Cl)N InChI=1S/C6H3Cl3N2O2/c7-1-3(10)2(8)5(9)11-4(1)6(12)13/h(H2,10,11)(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: The United Kingdom Picloram (Addendum 1) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance picloram 03Dec2009 2009 doi:10.2903/j.efsa.2009.1390
+Picloram 217-636-1 1918-02-1 single chemical entity Component is identical to the substance Picloram 217-636-1 1918-02-1 4-amino-3,5,6-trichloropyridine-2-carboxylic acid Picloram C6H3Cl3N2O2 C1(=C(C(=NC(=C1Cl)Cl)C(=O)O)Cl)N InChI=1S/C6H3Cl3N2O2/c7-1-3(10)2(8)5(9)11-4(1)6(12)13/h(H2,10,11)(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: The United Kingdom Picloram (Addendum 1) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance picloram 03Dec2009 2009 doi:10.2903/j.efsa.2009.1390
+Picloram 217-636-1 1918-02-1 single chemical entity Component is identical to the substance Picloram 217-636-1 1918-02-1 4-amino-3,5,6-trichloropyridine-2-carboxylic acid Picloram C6H3Cl3N2O2 C1(=C(C(=NC(=C1Cl)Cl)C(=O)O)Cl)N InChI=1S/C6H3Cl3N2O2/c7-1-3(10)2(8)5(9)11-4(1)6(12)13/h(H2,10,11)(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: The United Kingdom Picloram (Addendum 1) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance picloram 03Dec2009 2009 doi:10.2903/j.efsa.2009.1390
+Pyriproxyfen 95737-68-1 single chemical entity Component is identical to the substance Pyriproxyfen 95737-68-1 2-[1-methyl-2-(4-phenoxyphenoxy)ethoxy]pyridine Pyriproxyfen C20H19NO3 CC(OC3=NC=CC=C3)COC2=CC=C(C=C2)OC1=CC=CC=C1 InChI=1S/C20H19NO3/c1-16(23-20-9-5-6-14-21-20)15-22-17-10-12-19(13-11-17)24-18-7-3-2-4-8-18/h2-14,16H,15H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Pyriproxyfen 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance pyriproxyfen 06Aug2009 2009 doi:10.2903/j.efsa.2009.336r
+Pyriproxyfen 95737-68-1 single chemical entity Component is identical to the substance Pyriproxyfen 95737-68-1 2-[1-methyl-2-(4-phenoxyphenoxy)ethoxy]pyridine Pyriproxyfen C20H19NO3 CC(OC3=NC=CC=C3)COC2=CC=C(C=C2)OC1=CC=CC=C1 InChI=1S/C20H19NO3/c1-16(23-20-9-5-6-14-21-20)15-22-17-10-12-19(13-11-17)24-18-7-3-2-4-8-18/h2-14,16H,15H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Pyriproxyfen 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance pyriproxyfen 06Aug2009 2009 doi:10.2903/j.efsa.2009.336r
+Pyriproxyfen 95737-68-1 single chemical entity Component is identical to the substance Pyriproxyfen 95737-68-1 2-[1-methyl-2-(4-phenoxyphenoxy)ethoxy]pyridine Pyriproxyfen C20H19NO3 CC(OC3=NC=CC=C3)COC2=CC=C(C=C2)OC1=CC=CC=C1 InChI=1S/C20H19NO3/c1-16(23-20-9-5-6-14-21-20)15-22-17-10-12-19(13-11-17)24-18-7-3-2-4-8-18/h2-14,16H,15H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Pyriproxyfen 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance pyriproxyfen 06Aug2009 2009 doi:10.2903/j.efsa.2009.336r
+Pyriproxyfen 95737-68-1 single chemical entity Component is identical to the substance Pyriproxyfen 95737-68-1 2-[1-methyl-2-(4-phenoxyphenoxy)ethoxy]pyridine Pyriproxyfen C20H19NO3 CC(OC3=NC=CC=C3)COC2=CC=C(C=C2)OC1=CC=CC=C1 InChI=1S/C20H19NO3/c1-16(23-20-9-5-6-14-21-20)15-22-17-10-12-19(13-11-17)24-18-7-3-2-4-8-18/h2-14,16H,15H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Pyriproxyfen 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance pyriproxyfen 06Aug2009 2009 doi:10.2903/j.efsa.2009.336r
+Pyriproxyfen 95737-68-1 single chemical entity Component is identical to the substance Pyriproxyfen 95737-68-1 2-[1-methyl-2-(4-phenoxyphenoxy)ethoxy]pyridine Pyriproxyfen C20H19NO3 CC(OC3=NC=CC=C3)COC2=CC=C(C=C2)OC1=CC=CC=C1 InChI=1S/C20H19NO3/c1-16(23-20-9-5-6-14-21-20)15-22-17-10-12-19(13-11-17)24-18-7-3-2-4-8-18/h2-14,16H,15H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Pyriproxyfen 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance pyriproxyfen 06Aug2009 2009 doi:10.2903/j.efsa.2009.336r
+Pyriproxyfen 95737-68-1 single chemical entity Component is identical to the substance Pyriproxyfen 95737-68-1 2-[1-methyl-2-(4-phenoxyphenoxy)ethoxy]pyridine Pyriproxyfen C20H19NO3 CC(OC3=NC=CC=C3)COC2=CC=C(C=C2)OC1=CC=CC=C1 InChI=1S/C20H19NO3/c1-16(23-20-9-5-6-14-21-20)15-22-17-10-12-19(13-11-17)24-18-7-3-2-4-8-18/h2-14,16H,15H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Pyriproxyfen 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance pyriproxyfen 06Aug2009 2009 doi:10.2903/j.efsa.2009.336r
+Pyriproxyfen 95737-68-1 single chemical entity Component is identical to the substance Pyriproxyfen 95737-68-1 2-[1-methyl-2-(4-phenoxyphenoxy)ethoxy]pyridine Pyriproxyfen C20H19NO3 CC(OC3=NC=CC=C3)COC2=CC=C(C=C2)OC1=CC=CC=C1 InChI=1S/C20H19NO3/c1-16(23-20-9-5-6-14-21-20)15-22-17-10-12-19(13-11-17)24-18-7-3-2-4-8-18/h2-14,16H,15H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Pyriproxyfen 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance pyriproxyfen 06Aug2009 2009 doi:10.2903/j.efsa.2009.336r
+Pyriproxyfen 95737-68-1 single chemical entity Component is identical to the substance Pyriproxyfen 95737-68-1 2-[1-methyl-2-(4-phenoxyphenoxy)ethoxy]pyridine Pyriproxyfen C20H19NO3 CC(OC3=NC=CC=C3)COC2=CC=C(C=C2)OC1=CC=CC=C1 InChI=1S/C20H19NO3/c1-16(23-20-9-5-6-14-21-20)15-22-17-10-12-19(13-11-17)24-18-7-3-2-4-8-18/h2-14,16H,15H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Pyriproxyfen 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance pyriproxyfen 06Aug2009 2009 doi:10.2903/j.efsa.2009.336r
+Pyriproxyfen 95737-68-1 single chemical entity Component is identical to the substance Pyriproxyfen 95737-68-1 2-[1-methyl-2-(4-phenoxyphenoxy)ethoxy]pyridine Pyriproxyfen C20H19NO3 CC(OC3=NC=CC=C3)COC2=CC=C(C=C2)OC1=CC=CC=C1 InChI=1S/C20H19NO3/c1-16(23-20-9-5-6-14-21-20)15-22-17-10-12-19(13-11-17)24-18-7-3-2-4-8-18/h2-14,16H,15H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Pyriproxyfen 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance pyriproxyfen 06Aug2009 2009 doi:10.2903/j.efsa.2009.336r
+Pyriproxyfen 95737-68-1 single chemical entity Component is identical to the substance Pyriproxyfen 95737-68-1 2-[1-methyl-2-(4-phenoxyphenoxy)ethoxy]pyridine Pyriproxyfen C20H19NO3 CC(OC3=NC=CC=C3)COC2=CC=C(C=C2)OC1=CC=CC=C1 InChI=1S/C20H19NO3/c1-16(23-20-9-5-6-14-21-20)15-22-17-10-12-19(13-11-17)24-18-7-3-2-4-8-18/h2-14,16H,15H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Pyriproxyfen 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance pyriproxyfen 06Aug2009 2009 doi:10.2903/j.efsa.2009.336r
+Pyriproxyfen 95737-68-1 single chemical entity Component is identical to the substance Pyriproxyfen 95737-68-1 2-[1-methyl-2-(4-phenoxyphenoxy)ethoxy]pyridine Pyriproxyfen C20H19NO3 CC(OC3=NC=CC=C3)COC2=CC=C(C=C2)OC1=CC=CC=C1 InChI=1S/C20H19NO3/c1-16(23-20-9-5-6-14-21-20)15-22-17-10-12-19(13-11-17)24-18-7-3-2-4-8-18/h2-14,16H,15H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Pyriproxyfen 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance pyriproxyfen 06Aug2009 2009 doi:10.2903/j.efsa.2009.336r
+Pyriproxyfen 95737-68-1 single chemical entity Component is identical to the substance Pyriproxyfen 95737-68-1 2-[1-methyl-2-(4-phenoxyphenoxy)ethoxy]pyridine Pyriproxyfen C20H19NO3 CC(OC3=NC=CC=C3)COC2=CC=C(C=C2)OC1=CC=CC=C1 InChI=1S/C20H19NO3/c1-16(23-20-9-5-6-14-21-20)15-22-17-10-12-19(13-11-17)24-18-7-3-2-4-8-18/h2-14,16H,15H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Pyriproxyfen 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance pyriproxyfen 06Aug2009 2009 doi:10.2903/j.efsa.2009.336r
+Pyriproxyfen 95737-68-1 single chemical entity Component is identical to the substance Pyriproxyfen 95737-68-1 2-[1-methyl-2-(4-phenoxyphenoxy)ethoxy]pyridine Pyriproxyfen C20H19NO3 CC(OC3=NC=CC=C3)COC2=CC=C(C=C2)OC1=CC=CC=C1 InChI=1S/C20H19NO3/c1-16(23-20-9-5-6-14-21-20)15-22-17-10-12-19(13-11-17)24-18-7-3-2-4-8-18/h2-14,16H,15H2,1H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Pyriproxyfen 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance pyriproxyfen 06Aug2009 2009 doi:10.2903/j.efsa.2009.336r
+Pyriproxyfen 95737-68-1 single chemical entity Component is identical to the substance Pyriproxyfen 95737-68-1 2-[1-methyl-2-(4-phenoxyphenoxy)ethoxy]pyridine Pyriproxyfen C20H19NO3 CC(OC3=NC=CC=C3)COC2=CC=C(C=C2)OC1=CC=CC=C1 InChI=1S/C20H19NO3/c1-16(23-20-9-5-6-14-21-20)15-22-17-10-12-19(13-11-17)24-18-7-3-2-4-8-18/h2-14,16H,15H2,1H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Pyriproxyfen 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance pyriproxyfen 06Aug2009 2009 doi:10.2903/j.efsa.2009.336r
+Pyriproxyfen 95737-68-1 single chemical entity Component is identical to the substance Pyriproxyfen 95737-68-1 2-[1-methyl-2-(4-phenoxyphenoxy)ethoxy]pyridine Pyriproxyfen C20H19NO3 CC(OC3=NC=CC=C3)COC2=CC=C(C=C2)OC1=CC=CC=C1 InChI=1S/C20H19NO3/c1-16(23-20-9-5-6-14-21-20)15-22-17-10-12-19(13-11-17)24-18-7-3-2-4-8-18/h2-14,16H,15H2,1H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Pyriproxyfen 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance pyriproxyfen 06Aug2009 2009 doi:10.2903/j.efsa.2009.336r
+Pyriproxyfen 95737-68-1 single chemical entity Component is identical to the substance Pyriproxyfen 95737-68-1 2-[1-methyl-2-(4-phenoxyphenoxy)ethoxy]pyridine Pyriproxyfen C20H19NO3 CC(OC3=NC=CC=C3)COC2=CC=C(C=C2)OC1=CC=CC=C1 InChI=1S/C20H19NO3/c1-16(23-20-9-5-6-14-21-20)15-22-17-10-12-19(13-11-17)24-18-7-3-2-4-8-18/h2-14,16H,15H2,1H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Pyriproxyfen 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance pyriproxyfen 06Aug2009 2009 doi:10.2903/j.efsa.2009.336r
+Pyriproxyfen 95737-68-1 single chemical entity Component is identical to the substance Pyriproxyfen 95737-68-1 2-[1-methyl-2-(4-phenoxyphenoxy)ethoxy]pyridine Pyriproxyfen C20H19NO3 CC(OC3=NC=CC=C3)COC2=CC=C(C=C2)OC1=CC=CC=C1 InChI=1S/C20H19NO3/c1-16(23-20-9-5-6-14-21-20)15-22-17-10-12-19(13-11-17)24-18-7-3-2-4-8-18/h2-14,16H,15H2,1H3 organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Human (as organism) HeLa cells Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Pyriproxyfen 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance pyriproxyfen 06Aug2009 2009 doi:10.2903/j.efsa.2009.336r
+Pyriproxyfen 95737-68-1 single chemical entity Component is identical to the substance Pyriproxyfen 95737-68-1 2-[1-methyl-2-(4-phenoxyphenoxy)ethoxy]pyridine Pyriproxyfen C20H19NO3 CC(OC3=NC=CC=C3)COC2=CC=C(C=C2)OC1=CC=CC=C1 InChI=1S/C20H19NO3/c1-16(23-20-9-5-6-14-21-20)15-22-17-10-12-19(13-11-17)24-18-7-3-2-4-8-18/h2-14,16H,15H2,1H3 organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Human (as organism) HeLa cells Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Pyriproxyfen 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance pyriproxyfen 06Aug2009 2009 doi:10.2903/j.efsa.2009.336r
+Pyriproxyfen 95737-68-1 single chemical entity Component is identical to the substance Pyriproxyfen 95737-68-1 2-[1-methyl-2-(4-phenoxyphenoxy)ethoxy]pyridine Pyriproxyfen C20H19NO3 CC(OC3=NC=CC=C3)COC2=CC=C(C=C2)OC1=CC=CC=C1 InChI=1S/C20H19NO3/c1-16(23-20-9-5-6-14-21-20)15-22-17-10-12-19(13-11-17)24-18-7-3-2-4-8-18/h2-14,16H,15H2,1H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 40 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The Netherlands Pyriproxyfen 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance pyriproxyfen 06Aug2009 2009 doi:10.2903/j.efsa.2009.336r
+Pyriproxyfen 95737-68-1 single chemical entity Component is identical to the substance Pyriproxyfen 95737-68-1 2-[1-methyl-2-(4-phenoxyphenoxy)ethoxy]pyridine Pyriproxyfen C20H19NO3 CC(OC3=NC=CC=C3)COC2=CC=C(C=C2)OC1=CC=CC=C1 InChI=1S/C20H19NO3/c1-16(23-20-9-5-6-14-21-20)15-22-17-10-12-19(13-11-17)24-18-7-3-2-4-8-18/h2-14,16H,15H2,1H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 40 Male/Female oral: gavage 72.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The Netherlands Pyriproxyfen 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance pyriproxyfen 06Aug2009 2009 doi:10.2903/j.efsa.2009.336r
+Pyriproxyfen 95737-68-1 single chemical entity Component is identical to the substance Pyriproxyfen 95737-68-1 2-[1-methyl-2-(4-phenoxyphenoxy)ethoxy]pyridine Pyriproxyfen C20H19NO3 CC(OC3=NC=CC=C3)COC2=CC=C(C=C2)OC1=CC=CC=C1 InChI=1S/C20H19NO3/c1-16(23-20-9-5-6-14-21-20)15-22-17-10-12-19(13-11-17)24-18-7-3-2-4-8-18/h2-14,16H,15H2,1H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 40 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The Netherlands Pyriproxyfen 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance pyriproxyfen 06Aug2009 2009 doi:10.2903/j.efsa.2009.336r
+Propargite 219-006-1 2312-35-8 single chemical entity Component is identical to the substance Propargite 219-006-1 2312-35-8 2-(4-tert-butylphenoxy)cyclohexyl prop-2-yn-1-yl sulfite Propargite C19H26O4S CC(C)(C)c1ccc(cc1)OC2CCCCC2OS(=O)OCC#C InChI=1S/C19H26O4S/c1-5-14-21-24(20)23-18-9-7-6-8-17(18)22-16-12-10-15(11-13-16)19(2,3)4/h1,10-13,17-18H,6-9,14H2,2-4H3 organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: France Propargite 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance propargite 11May2011 2011 doi:10.2903/j.efsa.2011.2087
+Propargite 219-006-1 2312-35-8 single chemical entity Component is identical to the substance Propargite 219-006-1 2312-35-8 2-(4-tert-butylphenoxy)cyclohexyl prop-2-yn-1-yl sulfite Propargite C19H26O4S CC(C)(C)c1ccc(cc1)OC2CCCCC2OS(=O)OCC#C InChI=1S/C19H26O4S/c1-5-14-21-24(20)23-18-9-7-6-8-17(18)22-16-12-10-15(11-13-16)19(2,3)4/h1,10-13,17-18H,6-9,14H2,2-4H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: France Propargite 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance propargite 11May2011 2011 doi:10.2903/j.efsa.2011.2087
+Propargite 219-006-1 2312-35-8 single chemical entity Component is identical to the substance Propargite 219-006-1 2312-35-8 2-(4-tert-butylphenoxy)cyclohexyl prop-2-yn-1-yl sulfite Propargite C19H26O4S CC(C)(C)c1ccc(cc1)OC2CCCCC2OS(=O)OCC#C InChI=1S/C19H26O4S/c1-5-14-21-24(20)23-18-9-7-6-8-17(18)22-16-12-10-15(11-13-16)19(2,3)4/h1,10-13,17-18H,6-9,14H2,2-4H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: France Propargite 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance propargite 11May2011 2011 doi:10.2903/j.efsa.2011.2087
+Propargite 219-006-1 2312-35-8 single chemical entity Component is identical to the substance Propargite 219-006-1 2312-35-8 2-(4-tert-butylphenoxy)cyclohexyl prop-2-yn-1-yl sulfite Propargite C19H26O4S CC(C)(C)c1ccc(cc1)OC2CCCCC2OS(=O)OCC#C InChI=1S/C19H26O4S/c1-5-14-21-24(20)23-18-9-7-6-8-17(18)22-16-12-10-15(11-13-16)19(2,3)4/h1,10-13,17-18H,6-9,14H2,2-4H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: France Propargite 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance propargite 11May2011 2011 doi:10.2903/j.efsa.2011.2087
+Propargite 219-006-1 2312-35-8 single chemical entity Component is identical to the substance Propargite 219-006-1 2312-35-8 2-(4-tert-butylphenoxy)cyclohexyl prop-2-yn-1-yl sulfite Propargite C19H26O4S CC(C)(C)c1ccc(cc1)OC2CCCCC2OS(=O)OCC#C InChI=1S/C19H26O4S/c1-5-14-21-24(20)23-18-9-7-6-8-17(18)22-16-12-10-15(11-13-16)19(2,3)4/h1,10-13,17-18H,6-9,14H2,2-4H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: France Propargite 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance propargite 11May2011 2011 doi:10.2903/j.efsa.2011.2087
+Propargite 219-006-1 2312-35-8 single chemical entity Component is identical to the substance Propargite 219-006-1 2312-35-8 2-(4-tert-butylphenoxy)cyclohexyl prop-2-yn-1-yl sulfite Propargite C19H26O4S CC(C)(C)c1ccc(cc1)OC2CCCCC2OS(=O)OCC#C InChI=1S/C19H26O4S/c1-5-14-21-24(20)23-18-9-7-6-8-17(18)22-16-12-10-15(11-13-16)19(2,3)4/h1,10-13,17-18H,6-9,14H2,2-4H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) ICR 10 Male/Female intraperitoneal 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: France Propargite 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance propargite 11May2011 2011 doi:10.2903/j.efsa.2011.2087
+Propargite 219-006-1 2312-35-8 single chemical entity Component is identical to the substance Propargite 219-006-1 2312-35-8 2-(4-tert-butylphenoxy)cyclohexyl prop-2-yn-1-yl sulfite Propargite C19H26O4S CC(C)(C)c1ccc(cc1)OC2CCCCC2OS(=O)OCC#C InChI=1S/C19H26O4S/c1-5-14-21-24(20)23-18-9-7-6-8-17(18)22-16-12-10-15(11-13-16)19(2,3)4/h1,10-13,17-18H,6-9,14H2,2-4H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) ICR 10 Male/Female intraperitoneal 72.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: France Propargite 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance propargite 11May2011 2011 doi:10.2903/j.efsa.2011.2087
+Propargite 219-006-1 2312-35-8 single chemical entity Component is identical to the substance Propargite 219-006-1 2312-35-8 2-(4-tert-butylphenoxy)cyclohexyl prop-2-yn-1-yl sulfite Propargite C19H26O4S CC(C)(C)c1ccc(cc1)OC2CCCCC2OS(=O)OCC#C InChI=1S/C19H26O4S/c1-5-14-21-24(20)23-18-9-7-6-8-17(18)22-16-12-10-15(11-13-16)19(2,3)4/h1,10-13,17-18H,6-9,14H2,2-4H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) ICR 10 Male/Female intraperitoneal 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: France Propargite 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance propargite 11May2011 2011 doi:10.2903/j.efsa.2011.2087
+Prosulfocarb 401-730-6 52888-80-9 single chemical entity Component is identical to the substance Prosulfocarb 401-730-6 52888-80-9 S-benzyl dipropylcarbamothioate Prosulfocarb C14H21NOS CCCN(CCC)C(=O)SCc1ccccc1 InChI=1S/C14H21NOS/c1-3-10-15(11-4-2)14(16)17-12-13-8-6-5-7-9-13/h5-9H,3-4,10-12H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Sweden Prosulfocarb 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prosulfocarb 28Aug2007 2007 doi:10.2903/j.efsa.2007.111r
+Prosulfocarb 401-730-6 52888-80-9 single chemical entity Component is identical to the substance Prosulfocarb 401-730-6 52888-80-9 S-benzyl dipropylcarbamothioate Prosulfocarb C14H21NOS CCCN(CCC)C(=O)SCc1ccccc1 InChI=1S/C14H21NOS/c1-3-10-15(11-4-2)14(16)17-12-13-8-6-5-7-9-13/h5-9H,3-4,10-12H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Sweden Prosulfocarb 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prosulfocarb 28Aug2007 2007 doi:10.2903/j.efsa.2007.111r
+Prosulfocarb 401-730-6 52888-80-9 single chemical entity Component is identical to the substance Prosulfocarb 401-730-6 52888-80-9 S-benzyl dipropylcarbamothioate Prosulfocarb C14H21NOS CCCN(CCC)C(=O)SCc1ccccc1 InChI=1S/C14H21NOS/c1-3-10-15(11-4-2)14(16)17-12-13-8-6-5-7-9-13/h5-9H,3-4,10-12H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Sweden Prosulfocarb 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prosulfocarb 28Aug2007 2007 doi:10.2903/j.efsa.2007.111r
+Prosulfocarb 401-730-6 52888-80-9 single chemical entity Component is identical to the substance Prosulfocarb 401-730-6 52888-80-9 S-benzyl dipropylcarbamothioate Prosulfocarb C14H21NOS CCCN(CCC)C(=O)SCc1ccccc1 InChI=1S/C14H21NOS/c1-3-10-15(11-4-2)14(16)17-12-13-8-6-5-7-9-13/h5-9H,3-4,10-12H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Sweden Prosulfocarb 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prosulfocarb 28Aug2007 2007 doi:10.2903/j.efsa.2007.111r
+Prosulfocarb 401-730-6 52888-80-9 single chemical entity Component is identical to the substance Prosulfocarb 401-730-6 52888-80-9 S-benzyl dipropylcarbamothioate Prosulfocarb C14H21NOS CCCN(CCC)C(=O)SCc1ccccc1 InChI=1S/C14H21NOS/c1-3-10-15(11-4-2)14(16)17-12-13-8-6-5-7-9-13/h5-9H,3-4,10-12H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Sweden Prosulfocarb 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prosulfocarb 28Aug2007 2007 doi:10.2903/j.efsa.2007.111r
+Prosulfocarb 401-730-6 52888-80-9 single chemical entity Component is identical to the substance Prosulfocarb 401-730-6 52888-80-9 S-benzyl dipropylcarbamothioate Prosulfocarb C14H21NOS CCCN(CCC)C(=O)SCc1ccccc1 InChI=1S/C14H21NOS/c1-3-10-15(11-4-2)14(16)17-12-13-8-6-5-7-9-13/h5-9H,3-4,10-12H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Sweden Prosulfocarb 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prosulfocarb 28Aug2007 2007 doi:10.2903/j.efsa.2007.111r
+Prosulfocarb 401-730-6 52888-80-9 single chemical entity Component is identical to the substance Prosulfocarb 401-730-6 52888-80-9 S-benzyl dipropylcarbamothioate Prosulfocarb C14H21NOS CCCN(CCC)C(=O)SCc1ccccc1 InChI=1S/C14H21NOS/c1-3-10-15(11-4-2)14(16)17-12-13-8-6-5-7-9-13/h5-9H,3-4,10-12H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Sweden Prosulfocarb 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prosulfocarb 28Aug2007 2007 doi:10.2903/j.efsa.2007.111r
+Prosulfocarb 401-730-6 52888-80-9 single chemical entity Component is identical to the substance Prosulfocarb 401-730-6 52888-80-9 S-benzyl dipropylcarbamothioate Prosulfocarb C14H21NOS CCCN(CCC)C(=O)SCc1ccccc1 InChI=1S/C14H21NOS/c1-3-10-15(11-4-2)14(16)17-12-13-8-6-5-7-9-13/h5-9H,3-4,10-12H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Sweden Prosulfocarb 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prosulfocarb 28Aug2007 2007 doi:10.2903/j.efsa.2007.111r
+Prosulfocarb 401-730-6 52888-80-9 single chemical entity Component is identical to the substance Prosulfocarb 401-730-6 52888-80-9 S-benzyl dipropylcarbamothioate Prosulfocarb C14H21NOS CCCN(CCC)C(=O)SCc1ccccc1 InChI=1S/C14H21NOS/c1-3-10-15(11-4-2)14(16)17-12-13-8-6-5-7-9-13/h5-9H,3-4,10-12H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Sweden Prosulfocarb 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prosulfocarb 28Aug2007 2007 doi:10.2903/j.efsa.2007.111r
+Prosulfocarb 401-730-6 52888-80-9 single chemical entity Component is identical to the substance Prosulfocarb 401-730-6 52888-80-9 S-benzyl dipropylcarbamothioate Prosulfocarb C14H21NOS CCCN(CCC)C(=O)SCc1ccccc1 InChI=1S/C14H21NOS/c1-3-10-15(11-4-2)14(16)17-12-13-8-6-5-7-9-13/h5-9H,3-4,10-12H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Sweden Prosulfocarb 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prosulfocarb 28Aug2007 2007 doi:10.2903/j.efsa.2007.111r
+Prosulfocarb 401-730-6 52888-80-9 single chemical entity Component is identical to the substance Prosulfocarb 401-730-6 52888-80-9 S-benzyl dipropylcarbamothioate Prosulfocarb C14H21NOS CCCN(CCC)C(=O)SCc1ccccc1 InChI=1S/C14H21NOS/c1-3-10-15(11-4-2)14(16)17-12-13-8-6-5-7-9-13/h5-9H,3-4,10-12H2,1-2H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Sweden Prosulfocarb 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prosulfocarb 28Aug2007 2007 doi:10.2903/j.efsa.2007.111r
+Prosulfocarb 401-730-6 52888-80-9 single chemical entity Component is identical to the substance Prosulfocarb 401-730-6 52888-80-9 S-benzyl dipropylcarbamothioate Prosulfocarb C14H21NOS CCCN(CCC)C(=O)SCc1ccccc1 InChI=1S/C14H21NOS/c1-3-10-15(11-4-2)14(16)17-12-13-8-6-5-7-9-13/h5-9H,3-4,10-12H2,1-2H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Positive no information RMS: Sweden Prosulfocarb 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prosulfocarb 28Aug2007 2007 doi:10.2903/j.efsa.2007.111r
+Prosulfocarb 401-730-6 52888-80-9 single chemical entity Component is identical to the substance Prosulfocarb 401-730-6 52888-80-9 S-benzyl dipropylcarbamothioate Prosulfocarb C14H21NOS CCCN(CCC)C(=O)SCc1ccccc1 InChI=1S/C14H21NOS/c1-3-10-15(11-4-2)14(16)17-12-13-8-6-5-7-9-13/h5-9H,3-4,10-12H2,1-2H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Sweden Prosulfocarb 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prosulfocarb 28Aug2007 2007 doi:10.2903/j.efsa.2007.111r
+Prosulfocarb 401-730-6 52888-80-9 single chemical entity Component is identical to the substance Prosulfocarb 401-730-6 52888-80-9 S-benzyl dipropylcarbamothioate Prosulfocarb C14H21NOS CCCN(CCC)C(=O)SCc1ccccc1 InChI=1S/C14H21NOS/c1-3-10-15(11-4-2)14(16)17-12-13-8-6-5-7-9-13/h5-9H,3-4,10-12H2,1-2H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Sweden Prosulfocarb 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prosulfocarb 28Aug2007 2007 doi:10.2903/j.efsa.2007.111r
+Prosulfocarb 401-730-6 52888-80-9 single chemical entity Component is identical to the substance Prosulfocarb 401-730-6 52888-80-9 S-benzyl dipropylcarbamothioate Prosulfocarb C14H21NOS CCCN(CCC)C(=O)SCc1ccccc1 InChI=1S/C14H21NOS/c1-3-10-15(11-4-2)14(16)17-12-13-8-6-5-7-9-13/h5-9H,3-4,10-12H2,1-2H3 organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Human (as organism) HeLa cells Not reported yes, concurrent vehicle without Negative RMS: Sweden Prosulfocarb 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prosulfocarb 28Aug2007 2007 doi:10.2903/j.efsa.2007.111r
+Prosulfocarb 401-730-6 52888-80-9 single chemical entity Component is identical to the substance Prosulfocarb 401-730-6 52888-80-9 S-benzyl dipropylcarbamothioate Prosulfocarb C14H21NOS CCCN(CCC)C(=O)SCc1ccccc1 InChI=1S/C14H21NOS/c1-3-10-15(11-4-2)14(16)17-12-13-8-6-5-7-9-13/h5-9H,3-4,10-12H2,1-2H3 organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Human (as organism) HeLa cells Not reported yes, concurrent vehicle with Negative RMS: Sweden Prosulfocarb 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prosulfocarb 28Aug2007 2007 doi:10.2903/j.efsa.2007.111r
+Prosulfocarb 401-730-6 52888-80-9 single chemical entity Component is identical to the substance Prosulfocarb 401-730-6 52888-80-9 S-benzyl dipropylcarbamothioate Prosulfocarb C14H21NOS CCCN(CCC)C(=O)SCc1ccccc1 InChI=1S/C14H21NOS/c1-3-10-15(11-4-2)14(16)17-12-13-8-6-5-7-9-13/h5-9H,3-4,10-12H2,1-2H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female oral: unspecified 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Sweden Prosulfocarb 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prosulfocarb 28Aug2007 2007 doi:10.2903/j.efsa.2007.111r
+Prosulfocarb 401-730-6 52888-80-9 single chemical entity Component is identical to the substance Prosulfocarb 401-730-6 52888-80-9 S-benzyl dipropylcarbamothioate Prosulfocarb C14H21NOS CCCN(CCC)C(=O)SCc1ccccc1 InChI=1S/C14H21NOS/c1-3-10-15(11-4-2)14(16)17-12-13-8-6-5-7-9-13/h5-9H,3-4,10-12H2,1-2H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female oral: unspecified 72.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Sweden Prosulfocarb 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prosulfocarb 28Aug2007 2007 doi:10.2903/j.efsa.2007.111r
+Prosulfocarb 401-730-6 52888-80-9 single chemical entity Component is identical to the substance Prosulfocarb 401-730-6 52888-80-9 S-benzyl dipropylcarbamothioate Prosulfocarb C14H21NOS CCCN(CCC)C(=O)SCc1ccccc1 InChI=1S/C14H21NOS/c1-3-10-15(11-4-2)14(16)17-12-13-8-6-5-7-9-13/h5-9H,3-4,10-12H2,1-2H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Sweden Prosulfocarb 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prosulfocarb 28Aug2007 2007 doi:10.2903/j.efsa.2007.111r
+Prosulfocarb 401-730-6 52888-80-9 single chemical entity Component is identical to the substance Prosulfocarb 401-730-6 52888-80-9 S-benzyl dipropylcarbamothioate Prosulfocarb C14H21NOS CCCN(CCC)C(=O)SCc1ccccc1 InChI=1S/C14H21NOS/c1-3-10-15(11-4-2)14(16)17-12-13-8-6-5-7-9-13/h5-9H,3-4,10-12H2,1-2H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Sweden Prosulfocarb (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prosulfocarb 28Aug2007 2007 doi:10.2903/j.efsa.2007.111r
+Prosulfocarb 401-730-6 52888-80-9 single chemical entity Component is identical to the substance Prosulfocarb 401-730-6 52888-80-9 S-benzyl dipropylcarbamothioate Prosulfocarb C14H21NOS CCCN(CCC)C(=O)SCc1ccccc1 InChI=1S/C14H21NOS/c1-3-10-15(11-4-2)14(16)17-12-13-8-6-5-7-9-13/h5-9H,3-4,10-12H2,1-2H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Sweden Prosulfocarb (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prosulfocarb 28Aug2007 2007 doi:10.2903/j.efsa.2007.111r
+Pyriofenone 688046-61-9 single chemical entity Component is identical to the substance Pyriofenone 688046-61-9 (5-Chloro-2-methoxy-4-methylpyridin-3-yl)-(2,3,4-trimethoxy-6-methylphenyl)methanone Not in list C18H20ClNO5 CC1=CC(=C(C(=C1C(=O)C2=C(C(=CN=C2OC)Cl)C)OC)OC)OC InChI=1S/C18H20ClNO5/c1-9-7-12(22-3)16(23-4)17(24-5)13(9)15(21)14-10(2)11(19)8-20-18(14)25-6/h7-8H,1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Pyriofenone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyriofenone. 03Apr2013 2013 doi:10.2903/j.efsa.2013.3147
+Pyriofenone 688046-61-9 single chemical entity Component is identical to the substance Pyriofenone 688046-61-9 (5-Chloro-2-methoxy-4-methylpyridin-3-yl)-(2,3,4-trimethoxy-6-methylphenyl)methanone Not in list C18H20ClNO5 CC1=CC(=C(C(=C1C(=O)C2=C(C(=CN=C2OC)Cl)C)OC)OC)OC InChI=1S/C18H20ClNO5/c1-9-7-12(22-3)16(23-4)17(24-5)13(9)15(21)14-10(2)11(19)8-20-18(14)25-6/h7-8H,1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Pyriofenone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyriofenone. 03Apr2013 2013 doi:10.2903/j.efsa.2013.3147
+Pyriofenone 688046-61-9 single chemical entity Component is identical to the substance Pyriofenone 688046-61-9 (5-Chloro-2-methoxy-4-methylpyridin-3-yl)-(2,3,4-trimethoxy-6-methylphenyl)methanone Not in list C18H20ClNO5 CC1=CC(=C(C(=C1C(=O)C2=C(C(=CN=C2OC)Cl)C)OC)OC)OC InChI=1S/C18H20ClNO5/c1-9-7-12(22-3)16(23-4)17(24-5)13(9)15(21)14-10(2)11(19)8-20-18(14)25-6/h7-8H,1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Pyriofenone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyriofenone. 03Apr2013 2013 doi:10.2903/j.efsa.2013.3147
+Pyriofenone 688046-61-9 single chemical entity Component is identical to the substance Pyriofenone 688046-61-9 (5-Chloro-2-methoxy-4-methylpyridin-3-yl)-(2,3,4-trimethoxy-6-methylphenyl)methanone Not in list C18H20ClNO5 CC1=CC(=C(C(=C1C(=O)C2=C(C(=CN=C2OC)Cl)C)OC)OC)OC InChI=1S/C18H20ClNO5/c1-9-7-12(22-3)16(23-4)17(24-5)13(9)15(21)14-10(2)11(19)8-20-18(14)25-6/h7-8H,1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Pyriofenone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyriofenone. 03Apr2013 2013 doi:10.2903/j.efsa.2013.3147
+Pyriofenone 688046-61-9 single chemical entity Component is identical to the substance Pyriofenone 688046-61-9 (5-Chloro-2-methoxy-4-methylpyridin-3-yl)-(2,3,4-trimethoxy-6-methylphenyl)methanone Not in list C18H20ClNO5 CC1=CC(=C(C(=C1C(=O)C2=C(C(=CN=C2OC)Cl)C)OC)OC)OC InChI=1S/C18H20ClNO5/c1-9-7-12(22-3)16(23-4)17(24-5)13(9)15(21)14-10(2)11(19)8-20-18(14)25-6/h7-8H,1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Pyriofenone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyriofenone. 03Apr2013 2013 doi:10.2903/j.efsa.2013.3147
+Pyriofenone 688046-61-9 single chemical entity Component is identical to the substance Pyriofenone 688046-61-9 (5-Chloro-2-methoxy-4-methylpyridin-3-yl)-(2,3,4-trimethoxy-6-methylphenyl)methanone Not in list C18H20ClNO5 CC1=CC(=C(C(=C1C(=O)C2=C(C(=CN=C2OC)Cl)C)OC)OC)OC InChI=1S/C18H20ClNO5/c1-9-7-12(22-3)16(23-4)17(24-5)13(9)15(21)14-10(2)11(19)8-20-18(14)25-6/h7-8H,1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Pyriofenone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyriofenone. 03Apr2013 2013 doi:10.2903/j.efsa.2013.3147
+Pyriofenone 688046-61-9 single chemical entity Component is identical to the substance Pyriofenone 688046-61-9 (5-Chloro-2-methoxy-4-methylpyridin-3-yl)-(2,3,4-trimethoxy-6-methylphenyl)methanone Not in list C18H20ClNO5 CC1=CC(=C(C(=C1C(=O)C2=C(C(=CN=C2OC)Cl)C)OC)OC)OC InChI=1S/C18H20ClNO5/c1-9-7-12(22-3)16(23-4)17(24-5)13(9)15(21)14-10(2)11(19)8-20-18(14)25-6/h7-8H,1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Pyriofenone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyriofenone. 03Apr2013 2013 doi:10.2903/j.efsa.2013.3147
+Pyriofenone 688046-61-9 single chemical entity Component is identical to the substance Pyriofenone 688046-61-9 (5-Chloro-2-methoxy-4-methylpyridin-3-yl)-(2,3,4-trimethoxy-6-methylphenyl)methanone Not in list C18H20ClNO5 CC1=CC(=C(C(=C1C(=O)C2=C(C(=CN=C2OC)Cl)C)OC)OC)OC InChI=1S/C18H20ClNO5/c1-9-7-12(22-3)16(23-4)17(24-5)13(9)15(21)14-10(2)11(19)8-20-18(14)25-6/h7-8H,1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Pyriofenone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyriofenone. 03Apr2013 2013 doi:10.2903/j.efsa.2013.3147
+Pyriofenone 688046-61-9 single chemical entity Component is identical to the substance Pyriofenone 688046-61-9 (5-Chloro-2-methoxy-4-methylpyridin-3-yl)-(2,3,4-trimethoxy-6-methylphenyl)methanone Not in list C18H20ClNO5 CC1=CC(=C(C(=C1C(=O)C2=C(C(=CN=C2OC)Cl)C)OC)OC)OC InChI=1S/C18H20ClNO5/c1-9-7-12(22-3)16(23-4)17(24-5)13(9)15(21)14-10(2)11(19)8-20-18(14)25-6/h7-8H,1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Pyriofenone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyriofenone. 03Apr2013 2013 doi:10.2903/j.efsa.2013.3147
+Pyriofenone 688046-61-9 single chemical entity Component is identical to the substance Pyriofenone 688046-61-9 (5-Chloro-2-methoxy-4-methylpyridin-3-yl)-(2,3,4-trimethoxy-6-methylphenyl)methanone Not in list C18H20ClNO5 CC1=CC(=C(C(=C1C(=O)C2=C(C(=CN=C2OC)Cl)C)OC)OC)OC InChI=1S/C18H20ClNO5/c1-9-7-12(22-3)16(23-4)17(24-5)13(9)15(21)14-10(2)11(19)8-20-18(14)25-6/h7-8H,1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Pyriofenone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyriofenone. 03Apr2013 2013 doi:10.2903/j.efsa.2013.3147
+Pyriofenone 688046-61-9 single chemical entity Component is identical to the substance Pyriofenone 688046-61-9 (5-Chloro-2-methoxy-4-methylpyridin-3-yl)-(2,3,4-trimethoxy-6-methylphenyl)methanone Not in list C18H20ClNO5 CC1=CC(=C(C(=C1C(=O)C2=C(C(=CN=C2OC)Cl)C)OC)OC)OC InChI=1S/C18H20ClNO5/c1-9-7-12(22-3)16(23-4)17(24-5)13(9)15(21)14-10(2)11(19)8-20-18(14)25-6/h7-8H,1-6H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Positive RMS: The United Kingdom Pyriofenone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyriofenone. 03Apr2013 2013 doi:10.2903/j.efsa.2013.3147
+Pyriofenone 688046-61-9 single chemical entity Component is identical to the substance Pyriofenone 688046-61-9 (5-Chloro-2-methoxy-4-methylpyridin-3-yl)-(2,3,4-trimethoxy-6-methylphenyl)methanone Not in list C18H20ClNO5 CC1=CC(=C(C(=C1C(=O)C2=C(C(=CN=C2OC)Cl)C)OC)OC)OC InChI=1S/C18H20ClNO5/c1-9-7-12(22-3)16(23-4)17(24-5)13(9)15(21)14-10(2)11(19)8-20-18(14)25-6/h7-8H,1-6H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Positive RMS: The United Kingdom Pyriofenone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyriofenone. 03Apr2013 2013 doi:10.2903/j.efsa.2013.3147
+Pyriofenone 688046-61-9 single chemical entity Component is identical to the substance Pyriofenone 688046-61-9 (5-Chloro-2-methoxy-4-methylpyridin-3-yl)-(2,3,4-trimethoxy-6-methylphenyl)methanone Not in list C18H20ClNO5 CC1=CC(=C(C(=C1C(=O)C2=C(C(=CN=C2OC)Cl)C)OC)OC)OC InChI=1S/C18H20ClNO5/c1-9-7-12(22-3)16(23-4)17(24-5)13(9)15(21)14-10(2)11(19)8-20-18(14)25-6/h7-8H,1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: The United Kingdom Pyriofenone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyriofenone. 03Apr2013 2013 doi:10.2903/j.efsa.2013.3147
+Pyriofenone 688046-61-9 single chemical entity Component is identical to the substance Pyriofenone 688046-61-9 (5-Chloro-2-methoxy-4-methylpyridin-3-yl)-(2,3,4-trimethoxy-6-methylphenyl)methanone Not in list C18H20ClNO5 CC1=CC(=C(C(=C1C(=O)C2=C(C(=CN=C2OC)Cl)C)OC)OC)OC InChI=1S/C18H20ClNO5/c1-9-7-12(22-3)16(23-4)17(24-5)13(9)15(21)14-10(2)11(19)8-20-18(14)25-6/h7-8H,1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: The United Kingdom Pyriofenone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyriofenone. 03Apr2013 2013 doi:10.2903/j.efsa.2013.3147
+Pyriofenone 688046-61-9 single chemical entity Component is identical to the substance Pyriofenone 688046-61-9 (5-Chloro-2-methoxy-4-methylpyridin-3-yl)-(2,3,4-trimethoxy-6-methylphenyl)methanone Not in list C18H20ClNO5 CC1=CC(=C(C(=C1C(=O)C2=C(C(=CN=C2OC)Cl)C)OC)OC)OC InChI=1S/C18H20ClNO5/c1-9-7-12(22-3)16(23-4)17(24-5)13(9)15(21)14-10(2)11(19)8-20-18(14)25-6/h7-8H,1-6H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The United Kingdom Pyriofenone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyriofenone. 03Apr2013 2013 doi:10.2903/j.efsa.2013.3147
+Pyriofenone 688046-61-9 single chemical entity Component is identical to the substance Pyriofenone 688046-61-9 (5-Chloro-2-methoxy-4-methylpyridin-3-yl)-(2,3,4-trimethoxy-6-methylphenyl)methanone Not in list C18H20ClNO5 CC1=CC(=C(C(=C1C(=O)C2=C(C(=CN=C2OC)Cl)C)OC)OC)OC InChI=1S/C18H20ClNO5/c1-9-7-12(22-3)16(23-4)17(24-5)13(9)15(21)14-10(2)11(19)8-20-18(14)25-6/h7-8H,1-6H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The United Kingdom Pyriofenone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyriofenone. 03Apr2013 2013 doi:10.2903/j.efsa.2013.3147
+Pyriofenone 688046-61-9 single chemical entity Component is identical to the substance Pyriofenone 688046-61-9 (5-Chloro-2-methoxy-4-methylpyridin-3-yl)-(2,3,4-trimethoxy-6-methylphenyl)methanone Not in list C18H20ClNO5 CC1=CC(=C(C(=C1C(=O)C2=C(C(=CN=C2OC)Cl)C)OC)OC)OC InChI=1S/C18H20ClNO5/c1-9-7-12(22-3)16(23-4)17(24-5)13(9)15(21)14-10(2)11(19)8-20-18(14)25-6/h7-8H,1-6H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Crj:CD(SD) 3 Male oral: gavage 2.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Pyriofenone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyriofenone. 03Apr2013 2013 doi:10.2903/j.efsa.2013.3147
+Pyriofenone 688046-61-9 single chemical entity Component is identical to the substance Pyriofenone 688046-61-9 (5-Chloro-2-methoxy-4-methylpyridin-3-yl)-(2,3,4-trimethoxy-6-methylphenyl)methanone Not in list C18H20ClNO5 CC1=CC(=C(C(=C1C(=O)C2=C(C(=CN=C2OC)Cl)C)OC)OC)OC InChI=1S/C18H20ClNO5/c1-9-7-12(22-3)16(23-4)17(24-5)13(9)15(21)14-10(2)11(19)8-20-18(14)25-6/h7-8H,1-6H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Crj:CD(SD) 3 Male oral: gavage 16.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Pyriofenone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyriofenone. 03Apr2013 2013 doi:10.2903/j.efsa.2013.3147
+Pyriofenone 688046-61-9 single chemical entity Component is a metabolite of the substance (5-chloro-2-methoxy-4-methyl-3-pyridinyl)(4-hydroxy-2,3-dimethoxy-6-methylphenyl)methanone (5-chloro-2-methoxy-4-methylpyridin-3-yl)(4-hydroxy-2,3-dimethoxy-6-methylphenyl)methanone Not in list C17H18ClNO5 COc2ncc(Cl)c(C)c2C(=O)c1c(C)cc(O)c(OC)C1oc InChI=1/C17H18ClNO5/c1-8-6-11(20)15(22-3)16(23-4)12(8)14(21)13-9(2)10(18)7-19-17(13)24-5/h6-7,20H,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Pyriofenone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyriofenone. 03Apr2013 2013 doi:10.2903/j.efsa.2013.3147
+Pyriofenone 688046-61-9 single chemical entity Component is a metabolite of the substance (5-chloro-2-methoxy-4-methyl-3-pyridinyl)(4-hydroxy-2,3-dimethoxy-6-methylphenyl)methanone (5-chloro-2-methoxy-4-methylpyridin-3-yl)(4-hydroxy-2,3-dimethoxy-6-methylphenyl)methanone Not in list C17H18ClNO5 COc2ncc(Cl)c(C)c2C(=O)c1c(C)cc(O)c(OC)C1oc InChI=1/C17H18ClNO5/c1-8-6-11(20)15(22-3)16(23-4)12(8)14(21)13-9(2)10(18)7-19-17(13)24-5/h6-7,20H,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Pyriofenone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyriofenone. 03Apr2013 2013 doi:10.2903/j.efsa.2013.3147
+Pyriofenone 688046-61-9 single chemical entity Component is a metabolite of the substance (5-chloro-2-methoxy-4-methyl-3-pyridinyl)(4-hydroxy-2,3-dimethoxy-6-methylphenyl)methanone (5-chloro-2-methoxy-4-methylpyridin-3-yl)(4-hydroxy-2,3-dimethoxy-6-methylphenyl)methanone Not in list C17H18ClNO5 COc2ncc(Cl)c(C)c2C(=O)c1c(C)cc(O)c(OC)C1oc InChI=1/C17H18ClNO5/c1-8-6-11(20)15(22-3)16(23-4)12(8)14(21)13-9(2)10(18)7-19-17(13)24-5/h6-7,20H,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Pyriofenone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyriofenone. 03Apr2013 2013 doi:10.2903/j.efsa.2013.3147
+Pyriofenone 688046-61-9 single chemical entity Component is a metabolite of the substance (5-chloro-2-methoxy-4-methyl-3-pyridinyl)(4-hydroxy-2,3-dimethoxy-6-methylphenyl)methanone (5-chloro-2-methoxy-4-methylpyridin-3-yl)(4-hydroxy-2,3-dimethoxy-6-methylphenyl)methanone Not in list C17H18ClNO5 COc2ncc(Cl)c(C)c2C(=O)c1c(C)cc(O)c(OC)C1oc InChI=1/C17H18ClNO5/c1-8-6-11(20)15(22-3)16(23-4)12(8)14(21)13-9(2)10(18)7-19-17(13)24-5/h6-7,20H,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Pyriofenone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyriofenone. 03Apr2013 2013 doi:10.2903/j.efsa.2013.3147
+Pyriofenone 688046-61-9 single chemical entity Component is a metabolite of the substance (5-chloro-2-methoxy-4-methyl-3-pyridinyl)(4-hydroxy-2,3-dimethoxy-6-methylphenyl)methanone (5-chloro-2-methoxy-4-methylpyridin-3-yl)(4-hydroxy-2,3-dimethoxy-6-methylphenyl)methanone Not in list C17H18ClNO5 COc2ncc(Cl)c(C)c2C(=O)c1c(C)cc(O)c(OC)C1oc InChI=1/C17H18ClNO5/c1-8-6-11(20)15(22-3)16(23-4)12(8)14(21)13-9(2)10(18)7-19-17(13)24-5/h6-7,20H,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Pyriofenone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyriofenone. 03Apr2013 2013 doi:10.2903/j.efsa.2013.3147
+Pyriofenone 688046-61-9 single chemical entity Component is a metabolite of the substance (5-chloro-2-methoxy-4-methyl-3-pyridinyl)(4-hydroxy-2,3-dimethoxy-6-methylphenyl)methanone (5-chloro-2-methoxy-4-methylpyridin-3-yl)(4-hydroxy-2,3-dimethoxy-6-methylphenyl)methanone Not in list C17H18ClNO5 COc2ncc(Cl)c(C)c2C(=O)c1c(C)cc(O)c(OC)C1oc InChI=1/C17H18ClNO5/c1-8-6-11(20)15(22-3)16(23-4)12(8)14(21)13-9(2)10(18)7-19-17(13)24-5/h6-7,20H,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Pyriofenone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyriofenone. 03Apr2013 2013 doi:10.2903/j.efsa.2013.3147
+Pyriofenone 688046-61-9 single chemical entity Component is a metabolite of the substance (5-chloro-2-methoxy-4-methyl-3-pyridinyl)(4-hydroxy-2,3-dimethoxy-6-methylphenyl)methanone (5-chloro-2-methoxy-4-methylpyridin-3-yl)(4-hydroxy-2,3-dimethoxy-6-methylphenyl)methanone Not in list C17H18ClNO5 COc2ncc(Cl)c(C)c2C(=O)c1c(C)cc(O)c(OC)C1oc InChI=1/C17H18ClNO5/c1-8-6-11(20)15(22-3)16(23-4)12(8)14(21)13-9(2)10(18)7-19-17(13)24-5/h6-7,20H,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Pyriofenone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyriofenone. 03Apr2013 2013 doi:10.2903/j.efsa.2013.3147
+Pyriofenone 688046-61-9 single chemical entity Component is a metabolite of the substance (5-chloro-2-methoxy-4-methyl-3-pyridinyl)(4-hydroxy-2,3-dimethoxy-6-methylphenyl)methanone (5-chloro-2-methoxy-4-methylpyridin-3-yl)(4-hydroxy-2,3-dimethoxy-6-methylphenyl)methanone Not in list C17H18ClNO5 COc2ncc(Cl)c(C)c2C(=O)c1c(C)cc(O)c(OC)C1oc InChI=1/C17H18ClNO5/c1-8-6-11(20)15(22-3)16(23-4)12(8)14(21)13-9(2)10(18)7-19-17(13)24-5/h6-7,20H,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Pyriofenone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyriofenone. 03Apr2013 2013 doi:10.2903/j.efsa.2013.3147
+Pyriofenone 688046-61-9 single chemical entity Component is a metabolite of the substance (5-chloro-2-methoxy-4-methyl-3-pyridinyl)(4-hydroxy-2,3-dimethoxy-6-methylphenyl)methanone (5-chloro-2-methoxy-4-methylpyridin-3-yl)(4-hydroxy-2,3-dimethoxy-6-methylphenyl)methanone Not in list C17H18ClNO5 COc2ncc(Cl)c(C)c2C(=O)c1c(C)cc(O)c(OC)C1oc InChI=1/C17H18ClNO5/c1-8-6-11(20)15(22-3)16(23-4)12(8)14(21)13-9(2)10(18)7-19-17(13)24-5/h6-7,20H,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Pyriofenone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyriofenone. 03Apr2013 2013 doi:10.2903/j.efsa.2013.3147
+Pyriofenone 688046-61-9 single chemical entity Component is a metabolite of the substance (5-chloro-2-methoxy-4-methyl-3-pyridinyl)(4-hydroxy-2,3-dimethoxy-6-methylphenyl)methanone (5-chloro-2-methoxy-4-methylpyridin-3-yl)(4-hydroxy-2,3-dimethoxy-6-methylphenyl)methanone Not in list C17H18ClNO5 COc2ncc(Cl)c(C)c2C(=O)c1c(C)cc(O)c(OC)C1oc InChI=1/C17H18ClNO5/c1-8-6-11(20)15(22-3)16(23-4)12(8)14(21)13-9(2)10(18)7-19-17(13)24-5/h6-7,20H,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Pyriofenone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyriofenone. 03Apr2013 2013 doi:10.2903/j.efsa.2013.3147
+Pyridaben 405-700-3 96489-71-3 single chemical entity Component is identical to the substance Pyridaben 405-700-3 96489-71-3 2-tert-butyl-5-[(4-tert-butylbenzyl)thio]-4-chloropyridazin-3(2H)-one Pyridaben C19H25ClN2OS O=C1N(C(C)(C)C)N=CC(SCC2=CC=C(C(C)(C)C)C=C2)=C1Cl InChI=1S/C19H25ClN2OS/c1-18(2,3)14-9-7-13(8-10-14)12-24-15-11-21-22(19(4,5)6)17(23)16(15)20/h7-11H,12H2,1-6H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Pyridaben 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben 08Jun2010 2010 doi:10.2903/j.efsa.2010.1632
+Pyridaben 405-700-3 96489-71-3 single chemical entity Component is identical to the substance Pyridaben 405-700-3 96489-71-3 2-tert-butyl-5-[(4-tert-butylbenzyl)thio]-4-chloropyridazin-3(2H)-one Pyridaben C19H25ClN2OS O=C1N(C(C)(C)C)N=CC(SCC2=CC=C(C(C)(C)C)C=C2)=C1Cl InChI=1S/C19H25ClN2OS/c1-18(2,3)14-9-7-13(8-10-14)12-24-15-11-21-22(19(4,5)6)17(23)16(15)20/h7-11H,12H2,1-6H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Pyridaben 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben 08Jun2010 2010 doi:10.2903/j.efsa.2010.1632
+Pyridaben 405-700-3 96489-71-3 single chemical entity Component is identical to the substance Pyridaben 405-700-3 96489-71-3 2-tert-butyl-5-[(4-tert-butylbenzyl)thio]-4-chloropyridazin-3(2H)-one Pyridaben C19H25ClN2OS O=C1N(C(C)(C)C)N=CC(SCC2=CC=C(C(C)(C)C)C=C2)=C1Cl InChI=1S/C19H25ClN2OS/c1-18(2,3)14-9-7-13(8-10-14)12-24-15-11-21-22(19(4,5)6)17(23)16(15)20/h7-11H,12H2,1-6H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Pyridaben 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben 08Jun2010 2010 doi:10.2903/j.efsa.2010.1632
+Pyridaben 405-700-3 96489-71-3 single chemical entity Component is identical to the substance Pyridaben 405-700-3 96489-71-3 2-tert-butyl-5-[(4-tert-butylbenzyl)thio]-4-chloropyridazin-3(2H)-one Pyridaben C19H25ClN2OS O=C1N(C(C)(C)C)N=CC(SCC2=CC=C(C(C)(C)C)C=C2)=C1Cl InChI=1S/C19H25ClN2OS/c1-18(2,3)14-9-7-13(8-10-14)12-24-15-11-21-22(19(4,5)6)17(23)16(15)20/h7-11H,12H2,1-6H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Pyridaben 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben 08Jun2010 2010 doi:10.2903/j.efsa.2010.1632
+Pyridaben 405-700-3 96489-71-3 single chemical entity Component is identical to the substance Pyridaben 405-700-3 96489-71-3 2-tert-butyl-5-[(4-tert-butylbenzyl)thio]-4-chloropyridazin-3(2H)-one Pyridaben C19H25ClN2OS O=C1N(C(C)(C)C)N=CC(SCC2=CC=C(C(C)(C)C)C=C2)=C1Cl InChI=1S/C19H25ClN2OS/c1-18(2,3)14-9-7-13(8-10-14)12-24-15-11-21-22(19(4,5)6)17(23)16(15)20/h7-11H,12H2,1-6H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Pyridaben 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben 08Jun2010 2010 doi:10.2903/j.efsa.2010.1632
+Pyridaben 405-700-3 96489-71-3 single chemical entity Component is identical to the substance Pyridaben 405-700-3 96489-71-3 2-tert-butyl-5-[(4-tert-butylbenzyl)thio]-4-chloropyridazin-3(2H)-one Pyridaben C19H25ClN2OS O=C1N(C(C)(C)C)N=CC(SCC2=CC=C(C(C)(C)C)C=C2)=C1Cl InChI=1S/C19H25ClN2OS/c1-18(2,3)14-9-7-13(8-10-14)12-24-15-11-21-22(19(4,5)6)17(23)16(15)20/h7-11H,12H2,1-6H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Pyridaben 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben 08Jun2010 2010 doi:10.2903/j.efsa.2010.1632
+Pyridaben 405-700-3 96489-71-3 single chemical entity Component is identical to the substance Pyridaben 405-700-3 96489-71-3 2-tert-butyl-5-[(4-tert-butylbenzyl)thio]-4-chloropyridazin-3(2H)-one Pyridaben C19H25ClN2OS O=C1N(C(C)(C)C)N=CC(SCC2=CC=C(C(C)(C)C)C=C2)=C1Cl InChI=1S/C19H25ClN2OS/c1-18(2,3)14-9-7-13(8-10-14)12-24-15-11-21-22(19(4,5)6)17(23)16(15)20/h7-11H,12H2,1-6H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Pyridaben 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben 08Jun2010 2010 doi:10.2903/j.efsa.2010.1632
+Pyridaben 405-700-3 96489-71-3 single chemical entity Component is identical to the substance Pyridaben 405-700-3 96489-71-3 2-tert-butyl-5-[(4-tert-butylbenzyl)thio]-4-chloropyridazin-3(2H)-one Pyridaben C19H25ClN2OS O=C1N(C(C)(C)C)N=CC(SCC2=CC=C(C(C)(C)C)C=C2)=C1Cl InChI=1S/C19H25ClN2OS/c1-18(2,3)14-9-7-13(8-10-14)12-24-15-11-21-22(19(4,5)6)17(23)16(15)20/h7-11H,12H2,1-6H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Pyridaben 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben 08Jun2010 2010 doi:10.2903/j.efsa.2010.1632
+Pyridaben 405-700-3 96489-71-3 single chemical entity Component is identical to the substance Pyridaben 405-700-3 96489-71-3 2-tert-butyl-5-[(4-tert-butylbenzyl)thio]-4-chloropyridazin-3(2H)-one Pyridaben C19H25ClN2OS O=C1N(C(C)(C)C)N=CC(SCC2=CC=C(C(C)(C)C)C=C2)=C1Cl InChI=1S/C19H25ClN2OS/c1-18(2,3)14-9-7-13(8-10-14)12-24-15-11-21-22(19(4,5)6)17(23)16(15)20/h7-11H,12H2,1-6H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Pyridaben 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben 08Jun2010 2010 doi:10.2903/j.efsa.2010.1632
+Pyridaben 405-700-3 96489-71-3 single chemical entity Component is identical to the substance Pyridaben 405-700-3 96489-71-3 2-tert-butyl-5-[(4-tert-butylbenzyl)thio]-4-chloropyridazin-3(2H)-one Pyridaben C19H25ClN2OS O=C1N(C(C)(C)C)N=CC(SCC2=CC=C(C(C)(C)C)C=C2)=C1Cl InChI=1S/C19H25ClN2OS/c1-18(2,3)14-9-7-13(8-10-14)12-24-15-11-21-22(19(4,5)6)17(23)16(15)20/h7-11H,12H2,1-6H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Pyridaben 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben 08Jun2010 2010 doi:10.2903/j.efsa.2010.1632
+Pyridaben 405-700-3 96489-71-3 single chemical entity Component is identical to the substance Pyridaben 405-700-3 96489-71-3 2-tert-butyl-5-[(4-tert-butylbenzyl)thio]-4-chloropyridazin-3(2H)-one Pyridaben C19H25ClN2OS O=C1N(C(C)(C)C)N=CC(SCC2=CC=C(C(C)(C)C)C=C2)=C1Cl InChI=1S/C19H25ClN2OS/c1-18(2,3)14-9-7-13(8-10-14)12-24-15-11-21-22(19(4,5)6)17(23)16(15)20/h7-11H,12H2,1-6H3 organic compound Other Other DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) WP67 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Pyridaben 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben 08Jun2010 2010 doi:10.2903/j.efsa.2010.1632
+Pyridaben 405-700-3 96489-71-3 single chemical entity Component is identical to the substance Pyridaben 405-700-3 96489-71-3 2-tert-butyl-5-[(4-tert-butylbenzyl)thio]-4-chloropyridazin-3(2H)-one Pyridaben C19H25ClN2OS O=C1N(C(C)(C)C)N=CC(SCC2=CC=C(C(C)(C)C)C=C2)=C1Cl InChI=1S/C19H25ClN2OS/c1-18(2,3)14-9-7-13(8-10-14)12-24-15-11-21-22(19(4,5)6)17(23)16(15)20/h7-11H,12H2,1-6H3 organic compound Other Other DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) WP67 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Pyridaben 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben 08Jun2010 2010 doi:10.2903/j.efsa.2010.1632
+Pyridaben 405-700-3 96489-71-3 single chemical entity Component is identical to the substance Pyridaben 405-700-3 96489-71-3 2-tert-butyl-5-[(4-tert-butylbenzyl)thio]-4-chloropyridazin-3(2H)-one Pyridaben C19H25ClN2OS O=C1N(C(C)(C)C)N=CC(SCC2=CC=C(C(C)(C)C)C=C2)=C1Cl InChI=1S/C19H25ClN2OS/c1-18(2,3)14-9-7-13(8-10-14)12-24-15-11-21-22(19(4,5)6)17(23)16(15)20/h7-11H,12H2,1-6H3 organic compound Other Other DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Pyridaben 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben 08Jun2010 2010 doi:10.2903/j.efsa.2010.1632
+Pyridaben 405-700-3 96489-71-3 single chemical entity Component is identical to the substance Pyridaben 405-700-3 96489-71-3 2-tert-butyl-5-[(4-tert-butylbenzyl)thio]-4-chloropyridazin-3(2H)-one Pyridaben C19H25ClN2OS O=C1N(C(C)(C)C)N=CC(SCC2=CC=C(C(C)(C)C)C=C2)=C1Cl InChI=1S/C19H25ClN2OS/c1-18(2,3)14-9-7-13(8-10-14)12-24-15-11-21-22(19(4,5)6)17(23)16(15)20/h7-11H,12H2,1-6H3 organic compound Other Other DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Pyridaben 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben 08Jun2010 2010 doi:10.2903/j.efsa.2010.1632
+Pyridaben 405-700-3 96489-71-3 single chemical entity Component is identical to the substance Pyridaben 405-700-3 96489-71-3 2-tert-butyl-5-[(4-tert-butylbenzyl)thio]-4-chloropyridazin-3(2H)-one Pyridaben C19H25ClN2OS O=C1N(C(C)(C)C)N=CC(SCC2=CC=C(C(C)(C)C)C=C2)=C1Cl InChI=1S/C19H25ClN2OS/c1-18(2,3)14-9-7-13(8-10-14)12-24-15-11-21-22(19(4,5)6)17(23)16(15)20/h7-11H,12H2,1-6H3 organic compound Other Other DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) CM871 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Pyridaben 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben 08Jun2010 2010 doi:10.2903/j.efsa.2010.1632
+Pyridaben 405-700-3 96489-71-3 single chemical entity Component is identical to the substance Pyridaben 405-700-3 96489-71-3 2-tert-butyl-5-[(4-tert-butylbenzyl)thio]-4-chloropyridazin-3(2H)-one Pyridaben C19H25ClN2OS O=C1N(C(C)(C)C)N=CC(SCC2=CC=C(C(C)(C)C)C=C2)=C1Cl InChI=1S/C19H25ClN2OS/c1-18(2,3)14-9-7-13(8-10-14)12-24-15-11-21-22(19(4,5)6)17(23)16(15)20/h7-11H,12H2,1-6H3 organic compound Other Other DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) CM871 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Pyridaben 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben 08Jun2010 2010 doi:10.2903/j.efsa.2010.1632
+Pyridaben 405-700-3 96489-71-3 single chemical entity Component is identical to the substance Pyridaben 405-700-3 96489-71-3 2-tert-butyl-5-[(4-tert-butylbenzyl)thio]-4-chloropyridazin-3(2H)-one Pyridaben C19H25ClN2OS O=C1N(C(C)(C)C)N=CC(SCC2=CC=C(C(C)(C)C)C=C2)=C1Cl InChI=1S/C19H25ClN2OS/c1-18(2,3)14-9-7-13(8-10-14)12-24-15-11-21-22(19(4,5)6)17(23)16(15)20/h7-11H,12H2,1-6H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Pyridaben 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben 08Jun2010 2010 doi:10.2903/j.efsa.2010.1632
+Pyridaben 405-700-3 96489-71-3 single chemical entity Component is identical to the substance Pyridaben 405-700-3 96489-71-3 2-tert-butyl-5-[(4-tert-butylbenzyl)thio]-4-chloropyridazin-3(2H)-one Pyridaben C19H25ClN2OS O=C1N(C(C)(C)C)N=CC(SCC2=CC=C(C(C)(C)C)C=C2)=C1Cl InChI=1S/C19H25ClN2OS/c1-18(2,3)14-9-7-13(8-10-14)12-24-15-11-21-22(19(4,5)6)17(23)16(15)20/h7-11H,12H2,1-6H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Pyridaben 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben 08Jun2010 2010 doi:10.2903/j.efsa.2010.1632
+Pyridaben 405-700-3 96489-71-3 single chemical entity Component is identical to the substance Pyridaben 405-700-3 96489-71-3 2-tert-butyl-5-[(4-tert-butylbenzyl)thio]-4-chloropyridazin-3(2H)-one Pyridaben C19H25ClN2OS O=C1N(C(C)(C)C)N=CC(SCC2=CC=C(C(C)(C)C)C=C2)=C1Cl InChI=1S/C19H25ClN2OS/c1-18(2,3)14-9-7-13(8-10-14)12-24-15-11-21-22(19(4,5)6)17(23)16(15)20/h7-11H,12H2,1-6H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Pyridaben 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben 08Jun2010 2010 doi:10.2903/j.efsa.2010.1632
+Pyridaben 405-700-3 96489-71-3 single chemical entity Component is identical to the substance Pyridaben 405-700-3 96489-71-3 2-tert-butyl-5-[(4-tert-butylbenzyl)thio]-4-chloropyridazin-3(2H)-one Pyridaben C19H25ClN2OS O=C1N(C(C)(C)C)N=CC(SCC2=CC=C(C(C)(C)C)C=C2)=C1Cl InChI=1S/C19H25ClN2OS/c1-18(2,3)14-9-7-13(8-10-14)12-24-15-11-21-22(19(4,5)6)17(23)16(15)20/h7-11H,12H2,1-6H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Pyridaben 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben 08Jun2010 2010 doi:10.2903/j.efsa.2010.1632
+Pyridaben 405-700-3 96489-71-3 single chemical entity Component is identical to the substance Pyridaben 405-700-3 96489-71-3 2-tert-butyl-5-[(4-tert-butylbenzyl)thio]-4-chloropyridazin-3(2H)-one Pyridaben C19H25ClN2OS O=C1N(C(C)(C)C)N=CC(SCC2=CC=C(C(C)(C)C)C=C2)=C1Cl InChI=1S/C19H25ClN2OS/c1-18(2,3)14-9-7-13(8-10-14)12-24-15-11-21-22(19(4,5)6)17(23)16(15)20/h7-11H,12H2,1-6H3 organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Pyridaben 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben 08Jun2010 2010 doi:10.2903/j.efsa.2010.1632
+Pyridaben 405-700-3 96489-71-3 single chemical entity Component is identical to the substance Pyridaben 405-700-3 96489-71-3 2-tert-butyl-5-[(4-tert-butylbenzyl)thio]-4-chloropyridazin-3(2H)-one Pyridaben C19H25ClN2OS O=C1N(C(C)(C)C)N=CC(SCC2=CC=C(C(C)(C)C)C=C2)=C1Cl InChI=1S/C19H25ClN2OS/c1-18(2,3)14-9-7-13(8-10-14)12-24-15-11-21-22(19(4,5)6)17(23)16(15)20/h7-11H,12H2,1-6H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) ICR 12 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: The Netherlands Pyridaben 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben 08Jun2010 2010 doi:10.2903/j.efsa.2010.1632
+Pyridaben 405-700-3 96489-71-3 single chemical entity Component is identical to the substance Pyridaben 405-700-3 96489-71-3 2-tert-butyl-5-[(4-tert-butylbenzyl)thio]-4-chloropyridazin-3(2H)-one Pyridaben C19H25ClN2OS O=C1N(C(C)(C)C)N=CC(SCC2=CC=C(C(C)(C)C)C=C2)=C1Cl InChI=1S/C19H25ClN2OS/c1-18(2,3)14-9-7-13(8-10-14)12-24-15-11-21-22(19(4,5)6)17(23)16(15)20/h7-11H,12H2,1-6H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) ICR 12 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: The Netherlands Pyridaben 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben 08Jun2010 2010 doi:10.2903/j.efsa.2010.1632
+Pyridaben 405-700-3 96489-71-3 single chemical entity Component is identical to the substance Pyridaben 405-700-3 96489-71-3 2-tert-butyl-5-[(4-tert-butylbenzyl)thio]-4-chloropyridazin-3(2H)-one Pyridaben C19H25ClN2OS O=C1N(C(C)(C)C)N=CC(SCC2=CC=C(C(C)(C)C)C=C2)=C1Cl InChI=1S/C19H25ClN2OS/c1-18(2,3)14-9-7-13(8-10-14)12-24-15-11-21-22(19(4,5)6)17(23)16(15)20/h7-11H,12H2,1-6H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) ICR 12 Male/Female oral: gavage 72.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: The Netherlands Pyridaben 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben 08Jun2010 2010 doi:10.2903/j.efsa.2010.1632
+Pyridaben 405-700-3 96489-71-3 single chemical entity Component is a metabolite of the substance 2-(4-{[(1-tert-butyl-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)sulfanyl]methyl}phenyl)-2-methylpropanoic acid 2-(4-{[(1-tert-butyl-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)sulfanyl]methyl}phenyl)-2-methylpropanoic acid Not in list C19H23ClN2O3S CC(C)(C)N2N=CC(SCc1ccc(cc1)C(C)(C)C(=O)O)=C(Cl)C2=O InChI=1/C19H23ClN2O3S/c1-18(2,3)22-16(23)15(20)14(10-21-22)26-11-12-6-8-13(9-7-12)19(4,5)17(24)25/h6-10H,11H2,1-5H3,(H,24,25) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Pyridaben 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben 08Jun2010 2010 doi:10.2903/j.efsa.2010.1632
+Pyridaben 405-700-3 96489-71-3 single chemical entity Component is a metabolite of the substance 2-(4-{[(1-tert-butyl-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)sulfanyl]methyl}phenyl)-2-methylpropanoic acid 2-(4-{[(1-tert-butyl-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)sulfanyl]methyl}phenyl)-2-methylpropanoic acid Not in list C19H23ClN2O3S CC(C)(C)N2N=CC(SCc1ccc(cc1)C(C)(C)C(=O)O)=C(Cl)C2=O InChI=1/C19H23ClN2O3S/c1-18(2,3)22-16(23)15(20)14(10-21-22)26-11-12-6-8-13(9-7-12)19(4,5)17(24)25/h6-10H,11H2,1-5H3,(H,24,25) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Pyridaben 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben 08Jun2010 2010 doi:10.2903/j.efsa.2010.1632
+Pyridaben 405-700-3 96489-71-3 single chemical entity Component is a metabolite of the substance 2-(4-{[(1-tert-butyl-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)sulfanyl]methyl}phenyl)-2-methylpropanoic acid 2-(4-{[(1-tert-butyl-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)sulfanyl]methyl}phenyl)-2-methylpropanoic acid Not in list C19H23ClN2O3S CC(C)(C)N2N=CC(SCc1ccc(cc1)C(C)(C)C(=O)O)=C(Cl)C2=O InChI=1/C19H23ClN2O3S/c1-18(2,3)22-16(23)15(20)14(10-21-22)26-11-12-6-8-13(9-7-12)19(4,5)17(24)25/h6-10H,11H2,1-5H3,(H,24,25) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Pyridaben 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben 08Jun2010 2010 doi:10.2903/j.efsa.2010.1632
+Pyridaben 405-700-3 96489-71-3 single chemical entity Component is a metabolite of the substance 2-(4-{[(1-tert-butyl-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)sulfanyl]methyl}phenyl)-2-methylpropanoic acid 2-(4-{[(1-tert-butyl-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)sulfanyl]methyl}phenyl)-2-methylpropanoic acid Not in list C19H23ClN2O3S CC(C)(C)N2N=CC(SCc1ccc(cc1)C(C)(C)C(=O)O)=C(Cl)C2=O InChI=1/C19H23ClN2O3S/c1-18(2,3)22-16(23)15(20)14(10-21-22)26-11-12-6-8-13(9-7-12)19(4,5)17(24)25/h6-10H,11H2,1-5H3,(H,24,25) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Pyridaben 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben 08Jun2010 2010 doi:10.2903/j.efsa.2010.1632
+Pyridaben 405-700-3 96489-71-3 single chemical entity Component is a metabolite of the substance 2-(4-{[(1-tert-butyl-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)sulfanyl]methyl}phenyl)-2-methylpropanoic acid 2-(4-{[(1-tert-butyl-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)sulfanyl]methyl}phenyl)-2-methylpropanoic acid Not in list C19H23ClN2O3S CC(C)(C)N2N=CC(SCc1ccc(cc1)C(C)(C)C(=O)O)=C(Cl)C2=O InChI=1/C19H23ClN2O3S/c1-18(2,3)22-16(23)15(20)14(10-21-22)26-11-12-6-8-13(9-7-12)19(4,5)17(24)25/h6-10H,11H2,1-5H3,(H,24,25) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Pyridaben 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben 08Jun2010 2010 doi:10.2903/j.efsa.2010.1632
+Pyridaben 405-700-3 96489-71-3 single chemical entity Component is a metabolite of the substance 2-(4-{[(1-tert-butyl-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)sulfanyl]methyl}phenyl)-2-methylpropanoic acid 2-(4-{[(1-tert-butyl-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)sulfanyl]methyl}phenyl)-2-methylpropanoic acid Not in list C19H23ClN2O3S CC(C)(C)N2N=CC(SCc1ccc(cc1)C(C)(C)C(=O)O)=C(Cl)C2=O InChI=1/C19H23ClN2O3S/c1-18(2,3)22-16(23)15(20)14(10-21-22)26-11-12-6-8-13(9-7-12)19(4,5)17(24)25/h6-10H,11H2,1-5H3,(H,24,25) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Pyridaben 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben 08Jun2010 2010 doi:10.2903/j.efsa.2010.1632
+Pyridaben 405-700-3 96489-71-3 single chemical entity Component is a metabolite of the substance 2-(4-{[(1-tert-butyl-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)sulfanyl]methyl}phenyl)-2-methylpropanoic acid 2-(4-{[(1-tert-butyl-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)sulfanyl]methyl}phenyl)-2-methylpropanoic acid Not in list C19H23ClN2O3S CC(C)(C)N2N=CC(SCc1ccc(cc1)C(C)(C)C(=O)O)=C(Cl)C2=O InChI=1/C19H23ClN2O3S/c1-18(2,3)22-16(23)15(20)14(10-21-22)26-11-12-6-8-13(9-7-12)19(4,5)17(24)25/h6-10H,11H2,1-5H3,(H,24,25) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Pyridaben 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben 08Jun2010 2010 doi:10.2903/j.efsa.2010.1632
+Pyridaben 405-700-3 96489-71-3 single chemical entity Component is a metabolite of the substance 2-(4-{[(1-tert-butyl-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)sulfanyl]methyl}phenyl)-2-methylpropanoic acid 2-(4-{[(1-tert-butyl-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)sulfanyl]methyl}phenyl)-2-methylpropanoic acid Not in list C19H23ClN2O3S CC(C)(C)N2N=CC(SCc1ccc(cc1)C(C)(C)C(=O)O)=C(Cl)C2=O InChI=1/C19H23ClN2O3S/c1-18(2,3)22-16(23)15(20)14(10-21-22)26-11-12-6-8-13(9-7-12)19(4,5)17(24)25/h6-10H,11H2,1-5H3,(H,24,25) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Pyridaben 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben 08Jun2010 2010 doi:10.2903/j.efsa.2010.1632
+Pyridaben 405-700-3 96489-71-3 single chemical entity Component is a metabolite of the substance 2-(4-{[(1-tert-butyl-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)sulfanyl]methyl}phenyl)-2-methylpropanoic acid 2-(4-{[(1-tert-butyl-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)sulfanyl]methyl}phenyl)-2-methylpropanoic acid Not in list C19H23ClN2O3S CC(C)(C)N2N=CC(SCc1ccc(cc1)C(C)(C)C(=O)O)=C(Cl)C2=O InChI=1/C19H23ClN2O3S/c1-18(2,3)22-16(23)15(20)14(10-21-22)26-11-12-6-8-13(9-7-12)19(4,5)17(24)25/h6-10H,11H2,1-5H3,(H,24,25) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Pyridaben 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben 08Jun2010 2010 doi:10.2903/j.efsa.2010.1632
+Pyridaben 405-700-3 96489-71-3 single chemical entity Component is a metabolite of the substance 2-(4-{[(1-tert-butyl-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)sulfanyl]methyl}phenyl)-2-methylpropanoic acid 2-(4-{[(1-tert-butyl-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)sulfanyl]methyl}phenyl)-2-methylpropanoic acid Not in list C19H23ClN2O3S CC(C)(C)N2N=CC(SCc1ccc(cc1)C(C)(C)C(=O)O)=C(Cl)C2=O InChI=1/C19H23ClN2O3S/c1-18(2,3)22-16(23)15(20)14(10-21-22)26-11-12-6-8-13(9-7-12)19(4,5)17(24)25/h6-10H,11H2,1-5H3,(H,24,25) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Pyridaben 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben 08Jun2010 2010 doi:10.2903/j.efsa.2010.1632
+Pyridaben 405-700-3 96489-71-3 single chemical entity Component is a metabolite of the substance 2-(4-{[(1-tert-butyl-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)sulfanyl]methyl}phenyl)-2-methylpropanoic acid 2-(4-{[(1-tert-butyl-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)sulfanyl]methyl}phenyl)-2-methylpropanoic acid Not in list C19H23ClN2O3S CC(C)(C)N2N=CC(SCc1ccc(cc1)C(C)(C)C(=O)O)=C(Cl)C2=O InChI=1/C19H23ClN2O3S/c1-18(2,3)22-16(23)15(20)14(10-21-22)26-11-12-6-8-13(9-7-12)19(4,5)17(24)25/h6-10H,11H2,1-5H3,(H,24,25) organic compound Other Other DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Pyridaben 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben 08Jun2010 2010 doi:10.2903/j.efsa.2010.1632
+Pyridaben 405-700-3 96489-71-3 single chemical entity Component is a metabolite of the substance 2-(4-{[(1-tert-butyl-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)sulfanyl]methyl}phenyl)-2-methylpropanoic acid 2-(4-{[(1-tert-butyl-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)sulfanyl]methyl}phenyl)-2-methylpropanoic acid Not in list C19H23ClN2O3S CC(C)(C)N2N=CC(SCc1ccc(cc1)C(C)(C)C(=O)O)=C(Cl)C2=O InChI=1/C19H23ClN2O3S/c1-18(2,3)22-16(23)15(20)14(10-21-22)26-11-12-6-8-13(9-7-12)19(4,5)17(24)25/h6-10H,11H2,1-5H3,(H,24,25) organic compound Other Other DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Pyridaben 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben 08Jun2010 2010 doi:10.2903/j.efsa.2010.1632
+Pyridaben 405-700-3 96489-71-3 single chemical entity Component is a metabolite of the substance 2-(4-{[(1-tert-butyl-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)sulfanyl]methyl}phenyl)-2-methylpropanoic acid 2-(4-{[(1-tert-butyl-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)sulfanyl]methyl}phenyl)-2-methylpropanoic acid Not in list C19H23ClN2O3S CC(C)(C)N2N=CC(SCc1ccc(cc1)C(C)(C)C(=O)O)=C(Cl)C2=O InChI=1/C19H23ClN2O3S/c1-18(2,3)22-16(23)15(20)14(10-21-22)26-11-12-6-8-13(9-7-12)19(4,5)17(24)25/h6-10H,11H2,1-5H3,(H,24,25) organic compound Other Other DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) WP67 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Pyridaben 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben 08Jun2010 2010 doi:10.2903/j.efsa.2010.1632
+Pyridaben 405-700-3 96489-71-3 single chemical entity Component is a metabolite of the substance 2-(4-{[(1-tert-butyl-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)sulfanyl]methyl}phenyl)-2-methylpropanoic acid 2-(4-{[(1-tert-butyl-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)sulfanyl]methyl}phenyl)-2-methylpropanoic acid Not in list C19H23ClN2O3S CC(C)(C)N2N=CC(SCc1ccc(cc1)C(C)(C)C(=O)O)=C(Cl)C2=O InChI=1/C19H23ClN2O3S/c1-18(2,3)22-16(23)15(20)14(10-21-22)26-11-12-6-8-13(9-7-12)19(4,5)17(24)25/h6-10H,11H2,1-5H3,(H,24,25) organic compound Other Other DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) CM871 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Pyridaben 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben 08Jun2010 2010 doi:10.2903/j.efsa.2010.1632
+Pyridaben 405-700-3 96489-71-3 single chemical entity Component is a metabolite of the substance 2-(4-{[(1-tert-butyl-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)sulfanyl]methyl}phenyl)-2-methylpropanoic acid 2-(4-{[(1-tert-butyl-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)sulfanyl]methyl}phenyl)-2-methylpropanoic acid Not in list C19H23ClN2O3S CC(C)(C)N2N=CC(SCc1ccc(cc1)C(C)(C)C(=O)O)=C(Cl)C2=O InChI=1/C19H23ClN2O3S/c1-18(2,3)22-16(23)15(20)14(10-21-22)26-11-12-6-8-13(9-7-12)19(4,5)17(24)25/h6-10H,11H2,1-5H3,(H,24,25) organic compound Other Other DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) CM871 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Pyridaben 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben 08Jun2010 2010 doi:10.2903/j.efsa.2010.1632
+Pyridaben 405-700-3 96489-71-3 single chemical entity Component is a metabolite of the substance 2-(4-{[(1-tert-butyl-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)sulfanyl]methyl}phenyl)-2-methylpropanoic acid 2-(4-{[(1-tert-butyl-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)sulfanyl]methyl}phenyl)-2-methylpropanoic acid Not in list C19H23ClN2O3S CC(C)(C)N2N=CC(SCc1ccc(cc1)C(C)(C)C(=O)O)=C(Cl)C2=O InChI=1/C19H23ClN2O3S/c1-18(2,3)22-16(23)15(20)14(10-21-22)26-11-12-6-8-13(9-7-12)19(4,5)17(24)25/h6-10H,11H2,1-5H3,(H,24,25) organic compound Other Other DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) WP67 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Pyridaben 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben 08Jun2010 2010 doi:10.2903/j.efsa.2010.1632
+Meptyldinocap 228-088-8 131-72-6 single chemical entity Component is identical to the substance Meptyldinocap 228-088-8 131-72-6 (2,4-dinitro-6-octan-2-ylphenyl) (E)-but-2-enoate Meptyldinocap (sum of 2,4 DNOPC and 2,4 DNOP expressed as meptyldinocap) C18H24N2O6 CCCCCCC(C)C1=CC(=CC(=C1OC(=O)C=CC)[N+](=O)[O-])[N+](=O)[O-] InChI=1S/C18H24N2O6/c1-4-6-7-8-10-13(3)15-11-14(19(22)23)12-16(20(24)25)18(15)26-17(21)9-5-2/h5,9,11-13H,4,6-8,10H2,1-3H3/b9-5+ organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Meptyldinocap (DE-126) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance DE-126, referred to as meptyldinocap in Commission Decision 2006/589/EC 03Jan2014 2014 doi:10.2903/j.efsa.2014.3473
+Meptyldinocap 228-088-8 131-72-6 single chemical entity Component is identical to the substance Meptyldinocap 228-088-8 131-72-6 (2,4-dinitro-6-octan-2-ylphenyl) (E)-but-2-enoate Meptyldinocap (sum of 2,4 DNOPC and 2,4 DNOP expressed as meptyldinocap) C18H24N2O6 CCCCCCC(C)C1=CC(=CC(=C1OC(=O)C=CC)[N+](=O)[O-])[N+](=O)[O-] InChI=1S/C18H24N2O6/c1-4-6-7-8-10-13(3)15-11-14(19(22)23)12-16(20(24)25)18(15)26-17(21)9-5-2/h5,9,11-13H,4,6-8,10H2,1-3H3/b9-5+ organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Meptyldinocap (DE-126) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance DE-126, referred to as meptyldinocap in Commission Decision 2006/589/EC 03Jan2014 2014 doi:10.2903/j.efsa.2014.3473
+Meptyldinocap 228-088-8 131-72-6 single chemical entity Component is identical to the substance Meptyldinocap 228-088-8 131-72-6 (2,4-dinitro-6-octan-2-ylphenyl) (E)-but-2-enoate Meptyldinocap (sum of 2,4 DNOPC and 2,4 DNOP expressed as meptyldinocap) C18H24N2O6 CCCCCCC(C)C1=CC(=CC(=C1OC(=O)C=CC)[N+](=O)[O-])[N+](=O)[O-] InChI=1S/C18H24N2O6/c1-4-6-7-8-10-13(3)15-11-14(19(22)23)12-16(20(24)25)18(15)26-17(21)9-5-2/h5,9,11-13H,4,6-8,10H2,1-3H3/b9-5+ organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Meptyldinocap (DE-126) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance DE-126, referred to as meptyldinocap in Commission Decision 2006/589/EC 03Jan2014 2014 doi:10.2903/j.efsa.2014.3473
+Meptyldinocap 228-088-8 131-72-6 single chemical entity Component is identical to the substance Meptyldinocap 228-088-8 131-72-6 (2,4-dinitro-6-octan-2-ylphenyl) (E)-but-2-enoate Meptyldinocap (sum of 2,4 DNOPC and 2,4 DNOP expressed as meptyldinocap) C18H24N2O6 CCCCCCC(C)C1=CC(=CC(=C1OC(=O)C=CC)[N+](=O)[O-])[N+](=O)[O-] InChI=1S/C18H24N2O6/c1-4-6-7-8-10-13(3)15-11-14(19(22)23)12-16(20(24)25)18(15)26-17(21)9-5-2/h5,9,11-13H,4,6-8,10H2,1-3H3/b9-5+ organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Meptyldinocap (DE-126) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance DE-126, referred to as meptyldinocap in Commission Decision 2006/589/EC 03Jan2014 2014 doi:10.2903/j.efsa.2014.3473
+Meptyldinocap 228-088-8 131-72-6 single chemical entity Component is identical to the substance Meptyldinocap 228-088-8 131-72-6 (2,4-dinitro-6-octan-2-ylphenyl) (E)-but-2-enoate Meptyldinocap (sum of 2,4 DNOPC and 2,4 DNOP expressed as meptyldinocap) C18H24N2O6 CCCCCCC(C)C1=CC(=CC(=C1OC(=O)C=CC)[N+](=O)[O-])[N+](=O)[O-] InChI=1S/C18H24N2O6/c1-4-6-7-8-10-13(3)15-11-14(19(22)23)12-16(20(24)25)18(15)26-17(21)9-5-2/h5,9,11-13H,4,6-8,10H2,1-3H3/b9-5+ organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Meptyldinocap (DE-126) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance DE-126, referred to as meptyldinocap in Commission Decision 2006/589/EC 03Jan2014 2014 doi:10.2903/j.efsa.2014.3473
+Meptyldinocap 228-088-8 131-72-6 single chemical entity Component is identical to the substance Meptyldinocap 228-088-8 131-72-6 (2,4-dinitro-6-octan-2-ylphenyl) (E)-but-2-enoate Meptyldinocap (sum of 2,4 DNOPC and 2,4 DNOP expressed as meptyldinocap) C18H24N2O6 CCCCCCC(C)C1=CC(=CC(=C1OC(=O)C=CC)[N+](=O)[O-])[N+](=O)[O-] InChI=1S/C18H24N2O6/c1-4-6-7-8-10-13(3)15-11-14(19(22)23)12-16(20(24)25)18(15)26-17(21)9-5-2/h5,9,11-13H,4,6-8,10H2,1-3H3/b9-5+ organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Meptyldinocap (DE-126) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance DE-126, referred to as meptyldinocap in Commission Decision 2006/589/EC 03Jan2014 2014 doi:10.2903/j.efsa.2014.3473
+Meptyldinocap 228-088-8 131-72-6 single chemical entity Component is identical to the substance Meptyldinocap 228-088-8 131-72-6 (2,4-dinitro-6-octan-2-ylphenyl) (E)-but-2-enoate Meptyldinocap (sum of 2,4 DNOPC and 2,4 DNOP expressed as meptyldinocap) C18H24N2O6 CCCCCCC(C)C1=CC(=CC(=C1OC(=O)C=CC)[N+](=O)[O-])[N+](=O)[O-] InChI=1S/C18H24N2O6/c1-4-6-7-8-10-13(3)15-11-14(19(22)23)12-16(20(24)25)18(15)26-17(21)9-5-2/h5,9,11-13H,4,6-8,10H2,1-3H3/b9-5+ organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Meptyldinocap (DE-126) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance DE-126, referred to as meptyldinocap in Commission Decision 2006/589/EC 03Jan2014 2014 doi:10.2903/j.efsa.2014.3473
+Meptyldinocap 228-088-8 131-72-6 single chemical entity Component is identical to the substance Meptyldinocap 228-088-8 131-72-6 (2,4-dinitro-6-octan-2-ylphenyl) (E)-but-2-enoate Meptyldinocap (sum of 2,4 DNOPC and 2,4 DNOP expressed as meptyldinocap) C18H24N2O6 CCCCCCC(C)C1=CC(=CC(=C1OC(=O)C=CC)[N+](=O)[O-])[N+](=O)[O-] InChI=1S/C18H24N2O6/c1-4-6-7-8-10-13(3)15-11-14(19(22)23)12-16(20(24)25)18(15)26-17(21)9-5-2/h5,9,11-13H,4,6-8,10H2,1-3H3/b9-5+ organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Meptyldinocap (DE-126) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance DE-126, referred to as meptyldinocap in Commission Decision 2006/589/EC 03Jan2014 2014 doi:10.2903/j.efsa.2014.3473
+Meptyldinocap 228-088-8 131-72-6 single chemical entity Component is identical to the substance Meptyldinocap 228-088-8 131-72-6 (2,4-dinitro-6-octan-2-ylphenyl) (E)-but-2-enoate Meptyldinocap (sum of 2,4 DNOPC and 2,4 DNOP expressed as meptyldinocap) C18H24N2O6 CCCCCCC(C)C1=CC(=CC(=C1OC(=O)C=CC)[N+](=O)[O-])[N+](=O)[O-] InChI=1S/C18H24N2O6/c1-4-6-7-8-10-13(3)15-11-14(19(22)23)12-16(20(24)25)18(15)26-17(21)9-5-2/h5,9,11-13H,4,6-8,10H2,1-3H3/b9-5+ organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Meptyldinocap (DE-126) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance DE-126, referred to as meptyldinocap in Commission Decision 2006/589/EC 03Jan2014 2014 doi:10.2903/j.efsa.2014.3473
+Meptyldinocap 228-088-8 131-72-6 single chemical entity Component is identical to the substance Meptyldinocap 228-088-8 131-72-6 (2,4-dinitro-6-octan-2-ylphenyl) (E)-but-2-enoate Meptyldinocap (sum of 2,4 DNOPC and 2,4 DNOP expressed as meptyldinocap) C18H24N2O6 CCCCCCC(C)C1=CC(=CC(=C1OC(=O)C=CC)[N+](=O)[O-])[N+](=O)[O-] InChI=1S/C18H24N2O6/c1-4-6-7-8-10-13(3)15-11-14(19(22)23)12-16(20(24)25)18(15)26-17(21)9-5-2/h5,9,11-13H,4,6-8,10H2,1-3H3/b9-5+ organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Meptyldinocap (DE-126) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance DE-126, referred to as meptyldinocap in Commission Decision 2006/589/EC 03Jan2014 2014 doi:10.2903/j.efsa.2014.3473
+Meptyldinocap 228-088-8 131-72-6 single chemical entity Component is identical to the substance Meptyldinocap 228-088-8 131-72-6 (2,4-dinitro-6-octan-2-ylphenyl) (E)-but-2-enoate Meptyldinocap (sum of 2,4 DNOPC and 2,4 DNOP expressed as meptyldinocap) C18H24N2O6 CCCCCCC(C)C1=CC(=CC(=C1OC(=O)C=CC)[N+](=O)[O-])[N+](=O)[O-] InChI=1S/C18H24N2O6/c1-4-6-7-8-10-13(3)15-11-14(19(22)23)12-16(20(24)25)18(15)26-17(21)9-5-2/h5,9,11-13H,4,6-8,10H2,1-3H3/b9-5+ organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Rat (as animal) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Meptyldinocap (DE-126) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance DE-126, referred to as meptyldinocap in Commission Decision 2006/589/EC 03Jan2014 2014 doi:10.2903/j.efsa.2014.3473
+Meptyldinocap 228-088-8 131-72-6 single chemical entity Component is identical to the substance Meptyldinocap 228-088-8 131-72-6 (2,4-dinitro-6-octan-2-ylphenyl) (E)-but-2-enoate Meptyldinocap (sum of 2,4 DNOPC and 2,4 DNOP expressed as meptyldinocap) C18H24N2O6 CCCCCCC(C)C1=CC(=CC(=C1OC(=O)C=CC)[N+](=O)[O-])[N+](=O)[O-] InChI=1S/C18H24N2O6/c1-4-6-7-8-10-13(3)15-11-14(19(22)23)12-16(20(24)25)18(15)26-17(21)9-5-2/h5,9,11-13H,4,6-8,10H2,1-3H3/b9-5+ organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Rat (as animal) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Meptyldinocap (DE-126) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance DE-126, referred to as meptyldinocap in Commission Decision 2006/589/EC 03Jan2014 2014 doi:10.2903/j.efsa.2014.3473
+Meptyldinocap 228-088-8 131-72-6 single chemical entity Component is identical to the substance Meptyldinocap 228-088-8 131-72-6 (2,4-dinitro-6-octan-2-ylphenyl) (E)-but-2-enoate Meptyldinocap (sum of 2,4 DNOPC and 2,4 DNOP expressed as meptyldinocap) C18H24N2O6 CCCCCCC(C)C1=CC(=CC(=C1OC(=O)C=CC)[N+](=O)[O-])[N+](=O)[O-] InChI=1S/C18H24N2O6/c1-4-6-7-8-10-13(3)15-11-14(19(22)23)12-16(20(24)25)18(15)26-17(21)9-5-2/h5,9,11-13H,4,6-8,10H2,1-3H3/b9-5+ organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Meptyldinocap (DE-126) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance DE-126, referred to as meptyldinocap in Commission Decision 2006/589/EC 03Jan2014 2014 doi:10.2903/j.efsa.2014.3473
+Meptyldinocap 228-088-8 131-72-6 single chemical entity Component is identical to the substance Meptyldinocap 228-088-8 131-72-6 (2,4-dinitro-6-octan-2-ylphenyl) (E)-but-2-enoate Meptyldinocap (sum of 2,4 DNOPC and 2,4 DNOP expressed as meptyldinocap) C18H24N2O6 CCCCCCC(C)C1=CC(=CC(=C1OC(=O)C=CC)[N+](=O)[O-])[N+](=O)[O-] InChI=1S/C18H24N2O6/c1-4-6-7-8-10-13(3)15-11-14(19(22)23)12-16(20(24)25)18(15)26-17(21)9-5-2/h5,9,11-13H,4,6-8,10H2,1-3H3/b9-5+ organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Meptyldinocap (DE-126) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance DE-126, referred to as meptyldinocap in Commission Decision 2006/589/EC 03Jan2014 2014 doi:10.2903/j.efsa.2014.3473
+Meptyldinocap 228-088-8 131-72-6 single chemical entity Component is identical to the substance Meptyldinocap 228-088-8 131-72-6 (2,4-dinitro-6-octan-2-ylphenyl) (E)-but-2-enoate Meptyldinocap (sum of 2,4 DNOPC and 2,4 DNOP expressed as meptyldinocap) C18H24N2O6 CCCCCCC(C)C1=CC(=CC(=C1OC(=O)C=CC)[N+](=O)[O-])[N+](=O)[O-] InChI=1S/C18H24N2O6/c1-4-6-7-8-10-13(3)15-11-14(19(22)23)12-16(20(24)25)18(15)26-17(21)9-5-2/h5,9,11-13H,4,6-8,10H2,1-3H3/b9-5+ organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 6 Male oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The United Kingdom Meptyldinocap (DE-126) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance DE-126, referred to as meptyldinocap in Commission Decision 2006/589/EC 03Jan2014 2014 doi:10.2903/j.efsa.2014.3473
+Meptyldinocap 228-088-8 131-72-6 single chemical entity Component is identical to the substance Meptyldinocap 228-088-8 131-72-6 (2,4-dinitro-6-octan-2-ylphenyl) (E)-but-2-enoate Meptyldinocap (sum of 2,4 DNOPC and 2,4 DNOP expressed as meptyldinocap) C18H24N2O6 CCCCCCC(C)C1=CC(=CC(=C1OC(=O)C=CC)[N+](=O)[O-])[N+](=O)[O-] InChI=1S/C18H24N2O6/c1-4-6-7-8-10-13(3)15-11-14(19(22)23)12-16(20(24)25)18(15)26-17(21)9-5-2/h5,9,11-13H,4,6-8,10H2,1-3H3/b9-5+ organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 6 Male oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The United Kingdom Meptyldinocap (DE-126) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance DE-126, referred to as meptyldinocap in Commission Decision 2006/589/EC 03Jan2014 2014 doi:10.2903/j.efsa.2014.3473
+Mepiquat chloride 246-147-6 24307-26-4 single chemical entity Component is identical to the substance Mepiquat chloride 246-147-6 24307-26-4 1,1-Dimethylpiperidin-1-ium;chloride Not in list C7H16ClN C[N+]1(CCCCC1)C.[Cl-] InChI=1S/C7H16N.ClH/c1-8(2)6-4-3-5-7-8;/h3-7H2,1-2H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Mepiquat-chloride 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat 28Jul2008 2008 doi:10.2903/j.efsa.2008.146r
+Mepiquat chloride 246-147-6 24307-26-4 single chemical entity Component is identical to the substance Mepiquat chloride 246-147-6 24307-26-4 1,1-Dimethylpiperidin-1-ium;chloride Not in list C7H16ClN C[N+]1(CCCCC1)C.[Cl-] InChI=1S/C7H16N.ClH/c1-8(2)6-4-3-5-7-8;/h3-7H2,1-2H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Mepiquat-chloride 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat 28Jul2008 2008 doi:10.2903/j.efsa.2008.146r
+Mepiquat chloride 246-147-6 24307-26-4 single chemical entity Component is identical to the substance Mepiquat chloride 246-147-6 24307-26-4 1,1-Dimethylpiperidin-1-ium;chloride Not in list C7H16ClN C[N+]1(CCCCC1)C.[Cl-] InChI=1S/C7H16N.ClH/c1-8(2)6-4-3-5-7-8;/h3-7H2,1-2H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Mepiquat-chloride 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat 28Jul2008 2008 doi:10.2903/j.efsa.2008.146r
+Mepiquat chloride 246-147-6 24307-26-4 single chemical entity Component is identical to the substance Mepiquat chloride 246-147-6 24307-26-4 1,1-Dimethylpiperidin-1-ium;chloride Not in list C7H16ClN C[N+]1(CCCCC1)C.[Cl-] InChI=1S/C7H16N.ClH/c1-8(2)6-4-3-5-7-8;/h3-7H2,1-2H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Mepiquat-chloride 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat 28Jul2008 2008 doi:10.2903/j.efsa.2008.146r
+Mepiquat chloride 246-147-6 24307-26-4 single chemical entity Component is identical to the substance Mepiquat chloride 246-147-6 24307-26-4 1,1-Dimethylpiperidin-1-ium;chloride Not in list C7H16ClN C[N+]1(CCCCC1)C.[Cl-] InChI=1S/C7H16N.ClH/c1-8(2)6-4-3-5-7-8;/h3-7H2,1-2H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Mepiquat-chloride 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat 28Jul2008 2008 doi:10.2903/j.efsa.2008.146r
+Mepiquat chloride 246-147-6 24307-26-4 single chemical entity Component is identical to the substance Mepiquat chloride 246-147-6 24307-26-4 1,1-Dimethylpiperidin-1-ium;chloride Not in list C7H16ClN C[N+]1(CCCCC1)C.[Cl-] InChI=1S/C7H16N.ClH/c1-8(2)6-4-3-5-7-8;/h3-7H2,1-2H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Mepiquat-chloride 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat 28Jul2008 2008 doi:10.2903/j.efsa.2008.146r
+Mepiquat chloride 246-147-6 24307-26-4 single chemical entity Component is identical to the substance Mepiquat chloride 246-147-6 24307-26-4 1,1-Dimethylpiperidin-1-ium;chloride Not in list C7H16ClN C[N+]1(CCCCC1)C.[Cl-] InChI=1S/C7H16N.ClH/c1-8(2)6-4-3-5-7-8;/h3-7H2,1-2H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Mepiquat-chloride 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat 28Jul2008 2008 doi:10.2903/j.efsa.2008.146r
+Mepiquat chloride 246-147-6 24307-26-4 single chemical entity Component is identical to the substance Mepiquat chloride 246-147-6 24307-26-4 1,1-Dimethylpiperidin-1-ium;chloride Not in list C7H16ClN C[N+]1(CCCCC1)C.[Cl-] InChI=1S/C7H16N.ClH/c1-8(2)6-4-3-5-7-8;/h3-7H2,1-2H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Mepiquat-chloride 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat 28Jul2008 2008 doi:10.2903/j.efsa.2008.146r
+Mepiquat chloride 246-147-6 24307-26-4 single chemical entity Component is identical to the substance Mepiquat chloride 246-147-6 24307-26-4 1,1-Dimethylpiperidin-1-ium;chloride Not in list C7H16ClN C[N+]1(CCCCC1)C.[Cl-] InChI=1S/C7H16N.ClH/c1-8(2)6-4-3-5-7-8;/h3-7H2,1-2H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Mepiquat-chloride 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat 28Jul2008 2008 doi:10.2903/j.efsa.2008.146r
+Mepiquat chloride 246-147-6 24307-26-4 single chemical entity Component is identical to the substance Mepiquat chloride 246-147-6 24307-26-4 1,1-Dimethylpiperidin-1-ium;chloride Not in list C7H16ClN C[N+]1(CCCCC1)C.[Cl-] InChI=1S/C7H16N.ClH/c1-8(2)6-4-3-5-7-8;/h3-7H2,1-2H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Mepiquat-chloride 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat 28Jul2008 2008 doi:10.2903/j.efsa.2008.146r
+Mepiquat chloride 246-147-6 24307-26-4 single chemical entity Component is identical to the substance Mepiquat chloride 246-147-6 24307-26-4 1,1-Dimethylpiperidin-1-ium;chloride Not in list C7H16ClN C[N+]1(CCCCC1)C.[Cl-] InChI=1S/C7H16N.ClH/c1-8(2)6-4-3-5-7-8;/h3-7H2,1-2H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Mepiquat-chloride 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat 28Jul2008 2008 doi:10.2903/j.efsa.2008.146r
+Mepiquat chloride 246-147-6 24307-26-4 single chemical entity Component is identical to the substance Mepiquat chloride 246-147-6 24307-26-4 1,1-Dimethylpiperidin-1-ium;chloride Not in list C7H16ClN C[N+]1(CCCCC1)C.[Cl-] InChI=1S/C7H16N.ClH/c1-8(2)6-4-3-5-7-8;/h3-7H2,1-2H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Mepiquat-chloride 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat 28Jul2008 2008 doi:10.2903/j.efsa.2008.146r
+Mepiquat chloride 246-147-6 24307-26-4 single chemical entity Component is identical to the substance Mepiquat chloride 246-147-6 24307-26-4 1,1-Dimethylpiperidin-1-ium;chloride Not in list C7H16ClN C[N+]1(CCCCC1)C.[Cl-] InChI=1S/C7H16N.ClH/c1-8(2)6-4-3-5-7-8;/h3-7H2,1-2H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Mepiquat-chloride 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat 28Jul2008 2008 doi:10.2903/j.efsa.2008.146r
+Mepiquat chloride 246-147-6 24307-26-4 single chemical entity Component is identical to the substance Mepiquat chloride 246-147-6 24307-26-4 1,1-Dimethylpiperidin-1-ium;chloride Not in list C7H16ClN C[N+]1(CCCCC1)C.[Cl-] InChI=1S/C7H16N.ClH/c1-8(2)6-4-3-5-7-8;/h3-7H2,1-2H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Mepiquat-chloride 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat 28Jul2008 2008 doi:10.2903/j.efsa.2008.146r
+Mepiquat chloride 246-147-6 24307-26-4 single chemical entity Component is identical to the substance Mepiquat chloride 246-147-6 24307-26-4 1,1-Dimethylpiperidin-1-ium;chloride Not in list C7H16ClN C[N+]1(CCCCC1)C.[Cl-] InChI=1S/C7H16N.ClH/c1-8(2)6-4-3-5-7-8;/h3-7H2,1-2H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Mepiquat-chloride 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat 28Jul2008 2008 doi:10.2903/j.efsa.2008.146r
+Mepiquat chloride 246-147-6 24307-26-4 single chemical entity Component is identical to the substance Mepiquat chloride 246-147-6 24307-26-4 1,1-Dimethylpiperidin-1-ium;chloride Not in list C7H16ClN C[N+]1(CCCCC1)C.[Cl-] InChI=1S/C7H16N.ClH/c1-8(2)6-4-3-5-7-8;/h3-7H2,1-2H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Mepiquat-chloride 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat 28Jul2008 2008 doi:10.2903/j.efsa.2008.146r
+Mepiquat chloride 246-147-6 24307-26-4 single chemical entity Component is identical to the substance Mepiquat chloride 246-147-6 24307-26-4 1,1-Dimethylpiperidin-1-ium;chloride Not in list C7H16ClN C[N+]1(CCCCC1)C.[Cl-] InChI=1S/C7H16N.ClH/c1-8(2)6-4-3-5-7-8;/h3-7H2,1-2H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Mepiquat-chloride 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat 28Jul2008 2008 doi:10.2903/j.efsa.2008.146r
+Mepiquat chloride 246-147-6 24307-26-4 single chemical entity Component is identical to the substance Mepiquat chloride 246-147-6 24307-26-4 1,1-Dimethylpiperidin-1-ium;chloride Not in list C7H16ClN C[N+]1(CCCCC1)C.[Cl-] InChI=1S/C7H16N.ClH/c1-8(2)6-4-3-5-7-8;/h3-7H2,1-2H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Mepiquat-chloride 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat 28Jul2008 2008 doi:10.2903/j.efsa.2008.146r
+Mepiquat chloride 246-147-6 24307-26-4 single chemical entity Component is identical to the substance Mepiquat chloride 246-147-6 24307-26-4 1,1-Dimethylpiperidin-1-ium;chloride Not in list C7H16ClN C[N+]1(CCCCC1)C.[Cl-] InChI=1S/C7H16N.ClH/c1-8(2)6-4-3-5-7-8;/h3-7H2,1-2H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Mepiquat-chloride 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat 28Jul2008 2008 doi:10.2903/j.efsa.2008.146r
+Mepiquat chloride 246-147-6 24307-26-4 single chemical entity Component is identical to the substance Mepiquat chloride 246-147-6 24307-26-4 1,1-Dimethylpiperidin-1-ium;chloride Not in list C7H16ClN C[N+]1(CCCCC1)C.[Cl-] InChI=1S/C7H16N.ClH/c1-8(2)6-4-3-5-7-8;/h3-7H2,1-2H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Mepiquat-chloride 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat 28Jul2008 2008 doi:10.2903/j.efsa.2008.146r
+Mepiquat chloride 246-147-6 24307-26-4 single chemical entity Component is identical to the substance Mepiquat chloride 246-147-6 24307-26-4 1,1-Dimethylpiperidin-1-ium;chloride Not in list C7H16ClN C[N+]1(CCCCC1)C.[Cl-] InChI=1S/C7H16N.ClH/c1-8(2)6-4-3-5-7-8;/h3-7H2,1-2H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: The United Kingdom Mepiquat-chloride 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat 28Jul2008 2008 doi:10.2903/j.efsa.2008.146r
+Mepiquat chloride 246-147-6 24307-26-4 single chemical entity Component is identical to the substance Mepiquat chloride 246-147-6 24307-26-4 1,1-Dimethylpiperidin-1-ium;chloride Not in list C7H16ClN C[N+]1(CCCCC1)C.[Cl-] InChI=1S/C7H16N.ClH/c1-8(2)6-4-3-5-7-8;/h3-7H2,1-2H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: The United Kingdom Mepiquat-chloride 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat 28Jul2008 2008 doi:10.2903/j.efsa.2008.146r
+Mepiquat chloride 246-147-6 24307-26-4 single chemical entity Component is identical to the substance Mepiquat chloride 246-147-6 24307-26-4 1,1-Dimethylpiperidin-1-ium;chloride Not in list C7H16ClN C[N+]1(CCCCC1)C.[Cl-] InChI=1S/C7H16N.ClH/c1-8(2)6-4-3-5-7-8;/h3-7H2,1-2H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported no data without Negative RMS: The United Kingdom Mepiquat-chloride 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat 28Jul2008 2008 doi:10.2903/j.efsa.2008.146r
+Mepiquat chloride 246-147-6 24307-26-4 single chemical entity Component is identical to the substance Mepiquat chloride 246-147-6 24307-26-4 1,1-Dimethylpiperidin-1-ium;chloride Not in list C7H16ClN C[N+]1(CCCCC1)C.[Cl-] InChI=1S/C7H16N.ClH/c1-8(2)6-4-3-5-7-8;/h3-7H2,1-2H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes with Negative RMS: The United Kingdom Mepiquat-chloride 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat 28Jul2008 2008 doi:10.2903/j.efsa.2008.146r
+Mepiquat chloride 246-147-6 24307-26-4 single chemical entity Component is identical to the substance Mepiquat chloride 246-147-6 24307-26-4 1,1-Dimethylpiperidin-1-ium;chloride Not in list C7H16ClN C[N+]1(CCCCC1)C.[Cl-] InChI=1S/C7H16N.ClH/c1-8(2)6-4-3-5-7-8;/h3-7H2,1-2H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes without Negative RMS: The United Kingdom Mepiquat-chloride 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat 28Jul2008 2008 doi:10.2903/j.efsa.2008.146r
+Mepiquat chloride 246-147-6 24307-26-4 single chemical entity Component is identical to the substance Mepiquat chloride 246-147-6 24307-26-4 1,1-Dimethylpiperidin-1-ium;chloride Not in list C7H16ClN C[N+]1(CCCCC1)C.[Cl-] InChI=1S/C7H16N.ClH/c1-8(2)6-4-3-5-7-8;/h3-7H2,1-2H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes with Negative RMS: The United Kingdom Mepiquat-chloride 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat 28Jul2008 2008 doi:10.2903/j.efsa.2008.146r
+Mepiquat chloride 246-147-6 24307-26-4 single chemical entity Component is identical to the substance Mepiquat chloride 246-147-6 24307-26-4 1,1-Dimethylpiperidin-1-ium;chloride Not in list C7H16ClN C[N+]1(CCCCC1)C.[Cl-] InChI=1S/C7H16N.ClH/c1-8(2)6-4-3-5-7-8;/h3-7H2,1-2H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes without Negative RMS: The United Kingdom Mepiquat-chloride 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat 28Jul2008 2008 doi:10.2903/j.efsa.2008.146r
+Mepiquat chloride 246-147-6 24307-26-4 single chemical entity Component is identical to the substance Mepiquat chloride 246-147-6 24307-26-4 1,1-Dimethylpiperidin-1-ium;chloride Not in list C7H16ClN C[N+]1(CCCCC1)C.[Cl-] InChI=1S/C7H16N.ClH/c1-8(2)6-4-3-5-7-8;/h3-7H2,1-2H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI Male oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: The United Kingdom Mepiquat-chloride 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat 28Jul2008 2008 doi:10.2903/j.efsa.2008.146r
+Mepiquat chloride 246-147-6 24307-26-4 single chemical entity Component is identical to the substance Mepiquat chloride 246-147-6 24307-26-4 1,1-Dimethylpiperidin-1-ium;chloride Not in list C7H16ClN C[N+]1(CCCCC1)C.[Cl-] InChI=1S/C7H16N.ClH/c1-8(2)6-4-3-5-7-8;/h3-7H2,1-2H3;1H/q+1;/p-1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration dominant lethal assay in vivo According to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) No Acceptable House mouse (as animal) NMRI 20 Male oral: feed 5.0000000000 D yes not applicable Negative RMS: The United Kingdom Mepiquat-chloride 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat 28Jul2008 2008 doi:10.2903/j.efsa.2008.146r
+Mepiquat chloride 246-147-6 24307-26-4 single chemical entity Component is a metabolite of the substance 4-hydroxy-1,1-dimethylpiperidinium chloride 4-hydroxy-1,1-dimethylpiperidinium chloride Not in list C7H16ClNO [Cl-].C[N+]1(C)CCC(O)CC1 InChI=1/C7H16NO.ClH/c1-8(2)5-3-7(9)4-6-8;/h7,9H,3-6H2,1-2H3;1H/q+1;/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Mepiquat-chloride (Addendum 2) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat 28Jul2008 2008 doi:10.2903/j.efsa.2008.146r
+Mepiquat chloride 246-147-6 24307-26-4 single chemical entity Component is a metabolite of the substance 4-hydroxy-1,1-dimethylpiperidinium chloride 4-hydroxy-1,1-dimethylpiperidinium chloride Not in list C7H16ClNO [Cl-].C[N+]1(C)CCC(O)CC1 InChI=1/C7H16NO.ClH/c1-8(2)5-3-7(9)4-6-8;/h7,9H,3-6H2,1-2H3;1H/q+1;/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Mepiquat-chloride (Addendum 2) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat 28Jul2008 2008 doi:10.2903/j.efsa.2008.146r
+Mepiquat chloride 246-147-6 24307-26-4 single chemical entity Component is a metabolite of the substance 4-hydroxy-1,1-dimethylpiperidinium chloride 4-hydroxy-1,1-dimethylpiperidinium chloride Not in list C7H16ClNO [Cl-].C[N+]1(C)CCC(O)CC1 InChI=1/C7H16NO.ClH/c1-8(2)5-3-7(9)4-6-8;/h7,9H,3-6H2,1-2H3;1H/q+1;/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Mepiquat-chloride (Addendum 2) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat 28Jul2008 2008 doi:10.2903/j.efsa.2008.146r
+Mepiquat chloride 246-147-6 24307-26-4 single chemical entity Component is a metabolite of the substance 4-hydroxy-1,1-dimethylpiperidinium chloride 4-hydroxy-1,1-dimethylpiperidinium chloride Not in list C7H16ClNO [Cl-].C[N+]1(C)CCC(O)CC1 InChI=1/C7H16NO.ClH/c1-8(2)5-3-7(9)4-6-8;/h7,9H,3-6H2,1-2H3;1H/q+1;/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Mepiquat-chloride (Addendum 2) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat 28Jul2008 2008 doi:10.2903/j.efsa.2008.146r
+Mepiquat chloride 246-147-6 24307-26-4 single chemical entity Component is a metabolite of the substance 4-hydroxy-1,1-dimethylpiperidinium chloride 4-hydroxy-1,1-dimethylpiperidinium chloride Not in list C7H16ClNO [Cl-].C[N+]1(C)CCC(O)CC1 InChI=1/C7H16NO.ClH/c1-8(2)5-3-7(9)4-6-8;/h7,9H,3-6H2,1-2H3;1H/q+1;/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Mepiquat-chloride (Addendum 2) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat 28Jul2008 2008 doi:10.2903/j.efsa.2008.146r
+Mepiquat chloride 246-147-6 24307-26-4 single chemical entity Component is a metabolite of the substance 4-hydroxy-1,1-dimethylpiperidinium chloride 4-hydroxy-1,1-dimethylpiperidinium chloride Not in list C7H16ClNO [Cl-].C[N+]1(C)CCC(O)CC1 InChI=1/C7H16NO.ClH/c1-8(2)5-3-7(9)4-6-8;/h7,9H,3-6H2,1-2H3;1H/q+1;/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Mepiquat-chloride (Addendum 2) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat 28Jul2008 2008 doi:10.2903/j.efsa.2008.146r
+Mepiquat chloride 246-147-6 24307-26-4 single chemical entity Component is a metabolite of the substance 4-hydroxy-1,1-dimethylpiperidinium chloride 4-hydroxy-1,1-dimethylpiperidinium chloride Not in list C7H16ClNO [Cl-].C[N+]1(C)CCC(O)CC1 InChI=1/C7H16NO.ClH/c1-8(2)5-3-7(9)4-6-8;/h7,9H,3-6H2,1-2H3;1H/q+1;/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Mepiquat-chloride (Addendum 2) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat 28Jul2008 2008 doi:10.2903/j.efsa.2008.146r
+Mepiquat chloride 246-147-6 24307-26-4 single chemical entity Component is a metabolite of the substance 4-hydroxy-1,1-dimethylpiperidinium chloride 4-hydroxy-1,1-dimethylpiperidinium chloride Not in list C7H16ClNO [Cl-].C[N+]1(C)CCC(O)CC1 InChI=1/C7H16NO.ClH/c1-8(2)5-3-7(9)4-6-8;/h7,9H,3-6H2,1-2H3;1H/q+1;/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Mepiquat-chloride (Addendum 2) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat 28Jul2008 2008 doi:10.2903/j.efsa.2008.146r
+Mepiquat chloride 246-147-6 24307-26-4 single chemical entity Component is a metabolite of the substance 4-hydroxy-1,1-dimethylpiperidinium chloride 4-hydroxy-1,1-dimethylpiperidinium chloride Not in list C7H16ClNO [Cl-].C[N+]1(C)CCC(O)CC1 InChI=1/C7H16NO.ClH/c1-8(2)5-3-7(9)4-6-8;/h7,9H,3-6H2,1-2H3;1H/q+1;/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Mepiquat-chloride (Addendum 2) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat 28Jul2008 2008 doi:10.2903/j.efsa.2008.146r
+Mepiquat chloride 246-147-6 24307-26-4 single chemical entity Component is a metabolite of the substance 4-hydroxy-1,1-dimethylpiperidinium chloride 4-hydroxy-1,1-dimethylpiperidinium chloride Not in list C7H16ClNO [Cl-].C[N+]1(C)CCC(O)CC1 InChI=1/C7H16NO.ClH/c1-8(2)5-3-7(9)4-6-8;/h7,9H,3-6H2,1-2H3;1H/q+1;/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Mepiquat-chloride (Addendum 2) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat 28Jul2008 2008 doi:10.2903/j.efsa.2008.146r
+Oxamyl 23135-22-0 single chemical entity Component is identical to the substance Oxamyl 23135-22-0 (EZ)-N,N-dimethyl-2-methylcarbamoyloxyimino-2-(methylthio)acetamide Oxamyl C7H13N3O3S CNC(=O)O/N=C(/C(=O)N(C)C)\SC InChI=1S/C7H13N3O3S/c1-8-7(12)13-9-5(14-4)6(11)10(2)3/h1-4H3,(H,8,12)/b9-5- organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Ireland Oxamyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxamyl 31Mar2005 2005 doi:10.2903/j.efsa.2005.26r
+Oxamyl 23135-22-0 single chemical entity Component is identical to the substance Oxamyl 23135-22-0 (EZ)-N,N-dimethyl-2-methylcarbamoyloxyimino-2-(methylthio)acetamide Oxamyl C7H13N3O3S CNC(=O)O/N=C(/C(=O)N(C)C)\SC InChI=1S/C7H13N3O3S/c1-8-7(12)13-9-5(14-4)6(11)10(2)3/h1-4H3,(H,8,12)/b9-5- organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle without Negative RMS: Ireland Oxamyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxamyl 31Mar2005 2005 doi:10.2903/j.efsa.2005.26r
+Oxamyl 23135-22-0 single chemical entity Component is identical to the substance Oxamyl 23135-22-0 (EZ)-N,N-dimethyl-2-methylcarbamoyloxyimino-2-(methylthio)acetamide Oxamyl C7H13N3O3S CNC(=O)O/N=C(/C(=O)N(C)C)\SC InChI=1S/C7H13N3O3S/c1-8-7(12)13-9-5(14-4)6(11)10(2)3/h1-4H3,(H,8,12)/b9-5- organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Ireland Oxamyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxamyl 31Mar2005 2005 doi:10.2903/j.efsa.2005.26r
+Oxamyl 23135-22-0 single chemical entity Component is identical to the substance Oxamyl 23135-22-0 (EZ)-N,N-dimethyl-2-methylcarbamoyloxyimino-2-(methylthio)acetamide Oxamyl C7H13N3O3S CNC(=O)O/N=C(/C(=O)N(C)C)\SC InChI=1S/C7H13N3O3S/c1-8-7(12)13-9-5(14-4)6(11)10(2)3/h1-4H3,(H,8,12)/b9-5- organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Ireland Oxamyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxamyl 31Mar2005 2005 doi:10.2903/j.efsa.2005.26r
+Oxamyl 23135-22-0 single chemical entity Component is identical to the substance Oxamyl 23135-22-0 (EZ)-N,N-dimethyl-2-methylcarbamoyloxyimino-2-(methylthio)acetamide Oxamyl C7H13N3O3S CNC(=O)O/N=C(/C(=O)N(C)C)\SC InChI=1S/C7H13N3O3S/c1-8-7(12)13-9-5(14-4)6(11)10(2)3/h1-4H3,(H,8,12)/b9-5- organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle with Negative RMS: Ireland Oxamyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxamyl 31Mar2005 2005 doi:10.2903/j.efsa.2005.26r
+Oxamyl 23135-22-0 single chemical entity Component is identical to the substance Oxamyl 23135-22-0 (EZ)-N,N-dimethyl-2-methylcarbamoyloxyimino-2-(methylthio)acetamide Oxamyl C7H13N3O3S CNC(=O)O/N=C(/C(=O)N(C)C)\SC InChI=1S/C7H13N3O3S/c1-8-7(12)13-9-5(14-4)6(11)10(2)3/h1-4H3,(H,8,12)/b9-5- organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle without Negative RMS: Ireland Oxamyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxamyl 31Mar2005 2005 doi:10.2903/j.efsa.2005.26r
+Oxamyl 23135-22-0 single chemical entity Component is identical to the substance Oxamyl 23135-22-0 (EZ)-N,N-dimethyl-2-methylcarbamoyloxyimino-2-(methylthio)acetamide Oxamyl C7H13N3O3S CNC(=O)O/N=C(/C(=O)N(C)C)\SC InChI=1S/C7H13N3O3S/c1-8-7(12)13-9-5(14-4)6(11)10(2)3/h1-4H3,(H,8,12)/b9-5- organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Ireland Oxamyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxamyl 31Mar2005 2005 doi:10.2903/j.efsa.2005.26r
+Oxamyl 23135-22-0 single chemical entity Component is identical to the substance Oxamyl 23135-22-0 (EZ)-N,N-dimethyl-2-methylcarbamoyloxyimino-2-(methylthio)acetamide Oxamyl C7H13N3O3S CNC(=O)O/N=C(/C(=O)N(C)C)\SC InChI=1S/C7H13N3O3S/c1-8-7(12)13-9-5(14-4)6(11)10(2)3/h1-4H3,(H,8,12)/b9-5- organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Ireland Oxamyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxamyl 31Mar2005 2005 doi:10.2903/j.efsa.2005.26r
+Oxamyl 23135-22-0 single chemical entity Component is identical to the substance Oxamyl 23135-22-0 (EZ)-N,N-dimethyl-2-methylcarbamoyloxyimino-2-(methylthio)acetamide Oxamyl C7H13N3O3S CNC(=O)O/N=C(/C(=O)N(C)C)\SC InChI=1S/C7H13N3O3S/c1-8-7(12)13-9-5(14-4)6(11)10(2)3/h1-4H3,(H,8,12)/b9-5- organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Ireland Oxamyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxamyl 31Mar2005 2005 doi:10.2903/j.efsa.2005.26r
+Oxamyl 23135-22-0 single chemical entity Component is identical to the substance Oxamyl 23135-22-0 (EZ)-N,N-dimethyl-2-methylcarbamoyloxyimino-2-(methylthio)acetamide Oxamyl C7H13N3O3S CNC(=O)O/N=C(/C(=O)N(C)C)\SC InChI=1S/C7H13N3O3S/c1-8-7(12)13-9-5(14-4)6(11)10(2)3/h1-4H3,(H,8,12)/b9-5- organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle with Negative RMS: Ireland Oxamyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxamyl 31Mar2005 2005 doi:10.2903/j.efsa.2005.26r
+Oxamyl 23135-22-0 single chemical entity Component is identical to the substance Oxamyl 23135-22-0 (EZ)-N,N-dimethyl-2-methylcarbamoyloxyimino-2-(methylthio)acetamide Oxamyl C7H13N3O3S CNC(=O)O/N=C(/C(=O)N(C)C)\SC InChI=1S/C7H13N3O3S/c1-8-7(12)13-9-5(14-4)6(11)10(2)3/h1-4H3,(H,8,12)/b9-5- organic compound PubChem isomeric SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Ireland Oxamyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxamyl 31Mar2005 2005 doi:10.2903/j.efsa.2005.26r
+Oxamyl 23135-22-0 single chemical entity Component is identical to the substance Oxamyl 23135-22-0 (EZ)-N,N-dimethyl-2-methylcarbamoyloxyimino-2-(methylthio)acetamide Oxamyl C7H13N3O3S CNC(=O)O/N=C(/C(=O)N(C)C)\SC InChI=1S/C7H13N3O3S/c1-8-7(12)13-9-5(14-4)6(11)10(2)3/h1-4H3,(H,8,12)/b9-5- organic compound PubChem isomeric SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Ireland Oxamyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxamyl 31Mar2005 2005 doi:10.2903/j.efsa.2005.26r
+Oxamyl 23135-22-0 single chemical entity Component is identical to the substance Oxamyl 23135-22-0 (EZ)-N,N-dimethyl-2-methylcarbamoyloxyimino-2-(methylthio)acetamide Oxamyl C7H13N3O3S CNC(=O)O/N=C(/C(=O)N(C)C)\SC InChI=1S/C7H13N3O3S/c1-8-7(12)13-9-5(14-4)6(11)10(2)3/h1-4H3,(H,8,12)/b9-5- organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Ireland Oxamyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxamyl 31Mar2005 2005 doi:10.2903/j.efsa.2005.26r
+Oxamyl 23135-22-0 single chemical entity Component is identical to the substance Oxamyl 23135-22-0 (EZ)-N,N-dimethyl-2-methylcarbamoyloxyimino-2-(methylthio)acetamide Oxamyl C7H13N3O3S CNC(=O)O/N=C(/C(=O)N(C)C)\SC InChI=1S/C7H13N3O3S/c1-8-7(12)13-9-5(14-4)6(11)10(2)3/h1-4H3,(H,8,12)/b9-5- organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Ireland Oxamyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxamyl 31Mar2005 2005 doi:10.2903/j.efsa.2005.26r
+Oxamyl 23135-22-0 single chemical entity Component is identical to the substance Oxamyl 23135-22-0 (EZ)-N,N-dimethyl-2-methylcarbamoyloxyimino-2-(methylthio)acetamide Oxamyl C7H13N3O3S CNC(=O)O/N=C(/C(=O)N(C)C)\SC InChI=1S/C7H13N3O3S/c1-8-7(12)13-9-5(14-4)6(11)10(2)3/h1-4H3,(H,8,12)/b9-5- organic compound PubChem isomeric SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Ireland Oxamyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxamyl 31Mar2005 2005 doi:10.2903/j.efsa.2005.26r
+Oxamyl 23135-22-0 single chemical entity Component is identical to the substance Oxamyl 23135-22-0 (EZ)-N,N-dimethyl-2-methylcarbamoyloxyimino-2-(methylthio)acetamide Oxamyl C7H13N3O3S CNC(=O)O/N=C(/C(=O)N(C)C)\SC InChI=1S/C7H13N3O3S/c1-8-7(12)13-9-5(14-4)6(11)10(2)3/h1-4H3,(H,8,12)/b9-5- organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) ICR 20 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Ireland Oxamyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxamyl 31Mar2005 2005 doi:10.2903/j.efsa.2005.26r
+Oxamyl 23135-22-0 single chemical entity Component is identical to the substance Oxamyl 23135-22-0 (EZ)-N,N-dimethyl-2-methylcarbamoyloxyimino-2-(methylthio)acetamide Oxamyl C7H13N3O3S CNC(=O)O/N=C(/C(=O)N(C)C)\SC InChI=1S/C7H13N3O3S/c1-8-7(12)13-9-5(14-4)6(11)10(2)3/h1-4H3,(H,8,12)/b9-5- organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) ICR 20 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Ireland Oxamyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxamyl 31Mar2005 2005 doi:10.2903/j.efsa.2005.26r
+Oxamyl 23135-22-0 single chemical entity Component is a metabolite of the substance N,N-dimethyl-1-cyanoformamide [(cyanocarbonyl)azanediyl]dimethane Not in list C4H6N2O CN(C)C(=O)C#N InChI=1S/C4H6N2O/c1-6(2)4(7)3-5/h1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Ireland Oxamyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxamyl 31Mar2005 2005 doi:10.2903/j.efsa.2005.26r
+Oxamyl 23135-22-0 single chemical entity Component is a metabolite of the substance N,N-dimethyl-1-cyanoformamide [(cyanocarbonyl)azanediyl]dimethane Not in list C4H6N2O CN(C)C(=O)C#N InChI=1S/C4H6N2O/c1-6(2)4(7)3-5/h1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Ireland Oxamyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxamyl 31Mar2005 2005 doi:10.2903/j.efsa.2005.26r
+Oxamyl 23135-22-0 single chemical entity Component is a metabolite of the substance N,N-dimethyl-1-cyanoformamide [(cyanocarbonyl)azanediyl]dimethane Not in list C4H6N2O CN(C)C(=O)C#N InChI=1S/C4H6N2O/c1-6(2)4(7)3-5/h1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Ireland Oxamyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxamyl 31Mar2005 2005 doi:10.2903/j.efsa.2005.26r
+Oxamyl 23135-22-0 single chemical entity Component is a metabolite of the substance N,N-dimethyl-1-cyanoformamide [(cyanocarbonyl)azanediyl]dimethane Not in list C4H6N2O CN(C)C(=O)C#N InChI=1S/C4H6N2O/c1-6(2)4(7)3-5/h1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Ireland Oxamyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxamyl 31Mar2005 2005 doi:10.2903/j.efsa.2005.26r
+Oxamyl 23135-22-0 single chemical entity Component is a metabolite of the substance N,N-dimethyl-1-cyanoformamide [(cyanocarbonyl)azanediyl]dimethane Not in list C4H6N2O CN(C)C(=O)C#N InChI=1S/C4H6N2O/c1-6(2)4(7)3-5/h1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Ireland Oxamyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxamyl 31Mar2005 2005 doi:10.2903/j.efsa.2005.26r
+Oxamyl 23135-22-0 single chemical entity Component is a metabolite of the substance N,N-dimethyl-1-cyanoformamide [(cyanocarbonyl)azanediyl]dimethane Not in list C4H6N2O CN(C)C(=O)C#N InChI=1S/C4H6N2O/c1-6(2)4(7)3-5/h1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Ireland Oxamyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxamyl 31Mar2005 2005 doi:10.2903/j.efsa.2005.26r
+Oxamyl 23135-22-0 single chemical entity Component is a metabolite of the substance N,N-dimethyl-1-cyanoformamide [(cyanocarbonyl)azanediyl]dimethane Not in list C4H6N2O CN(C)C(=O)C#N InChI=1S/C4H6N2O/c1-6(2)4(7)3-5/h1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Ireland Oxamyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxamyl 31Mar2005 2005 doi:10.2903/j.efsa.2005.26r
+Oxamyl 23135-22-0 single chemical entity Component is a metabolite of the substance N,N-dimethyl-1-cyanoformamide [(cyanocarbonyl)azanediyl]dimethane Not in list C4H6N2O CN(C)C(=O)C#N InChI=1S/C4H6N2O/c1-6(2)4(7)3-5/h1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Ireland Oxamyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxamyl 31Mar2005 2005 doi:10.2903/j.efsa.2005.26r
+Oxamyl 23135-22-0 single chemical entity Component is a metabolite of the substance N,N-dimethyl-1-cyanoformamide [(cyanocarbonyl)azanediyl]dimethane Not in list C4H6N2O CN(C)C(=O)C#N InChI=1S/C4H6N2O/c1-6(2)4(7)3-5/h1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Ireland Oxamyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxamyl 31Mar2005 2005 doi:10.2903/j.efsa.2005.26r
+Oxamyl 23135-22-0 single chemical entity Component is a metabolite of the substance N,N-dimethyl-1-cyanoformamide [(cyanocarbonyl)azanediyl]dimethane Not in list C4H6N2O CN(C)C(=O)C#N InChI=1S/C4H6N2O/c1-6(2)4(7)3-5/h1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Ireland Oxamyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxamyl 31Mar2005 2005 doi:10.2903/j.efsa.2005.26r
+Pyraflufen-ethyl 603-347-1 129630-19-9 single chemical entity Component is identical to the substance Pyraflufen-ethyl 603-347-1 129630-19-9 ethyl 2-[2-chloro-5-[4-chloro-5-(difluoromethoxy)-1-methylpyrazol-3-yl]-4-fluorophenoxy]acetate Pyraflufen-ethyl C15H13Cl2F3N2O4 CCOC(=O)COC1=C(C=C(C(=C1)C2=NN(C(=C2Cl)OC(F)F)C)F)Cl InChI=1S/C15H13Cl2F3N2O4/c1-3-24-11(23)6-25-10-4-7(9(18)5-8(10)16)13-12(17)14(22(2)21-13)26-15(19)20/h4-5,15H,3,6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: The Netherlands Pyraflufen-ethyl (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyraflufen-ethyl 05Feb2015 2015 doi:10.2903/j.efsa.2015.4001
+Pyraflufen-ethyl 603-347-1 129630-19-9 single chemical entity Component is identical to the substance Pyraflufen-ethyl 603-347-1 129630-19-9 ethyl 2-[2-chloro-5-[4-chloro-5-(difluoromethoxy)-1-methylpyrazol-3-yl]-4-fluorophenoxy]acetate Pyraflufen-ethyl C15H13Cl2F3N2O4 CCOC(=O)COC1=C(C=C(C(=C1)C2=NN(C(=C2Cl)OC(F)F)C)F)Cl InChI=1S/C15H13Cl2F3N2O4/c1-3-24-11(23)6-25-10-4-7(9(18)5-8(10)16)13-12(17)14(22(2)21-13)26-15(19)20/h4-5,15H,3,6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: The Netherlands Pyraflufen-ethyl (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyraflufen-ethyl 05Feb2015 2015 doi:10.2903/j.efsa.2015.4001
+Pyraflufen-ethyl 603-347-1 129630-19-9 single chemical entity Component is identical to the substance Pyraflufen-ethyl 603-347-1 129630-19-9 ethyl 2-[2-chloro-5-[4-chloro-5-(difluoromethoxy)-1-methylpyrazol-3-yl]-4-fluorophenoxy]acetate Pyraflufen-ethyl C15H13Cl2F3N2O4 CCOC(=O)COC1=C(C=C(C(=C1)C2=NN(C(=C2Cl)OC(F)F)C)F)Cl InChI=1S/C15H13Cl2F3N2O4/c1-3-24-11(23)6-25-10-4-7(9(18)5-8(10)16)13-12(17)14(22(2)21-13)26-15(19)20/h4-5,15H,3,6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: The Netherlands Pyraflufen-ethyl (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyraflufen-ethyl 05Feb2015 2015 doi:10.2903/j.efsa.2015.4001
+Pyraflufen-ethyl 603-347-1 129630-19-9 single chemical entity Component is identical to the substance Pyraflufen-ethyl 603-347-1 129630-19-9 ethyl 2-[2-chloro-5-[4-chloro-5-(difluoromethoxy)-1-methylpyrazol-3-yl]-4-fluorophenoxy]acetate Pyraflufen-ethyl C15H13Cl2F3N2O4 CCOC(=O)COC1=C(C=C(C(=C1)C2=NN(C(=C2Cl)OC(F)F)C)F)Cl InChI=1S/C15H13Cl2F3N2O4/c1-3-24-11(23)6-25-10-4-7(9(18)5-8(10)16)13-12(17)14(22(2)21-13)26-15(19)20/h4-5,15H,3,6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: The Netherlands Pyraflufen-ethyl (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyraflufen-ethyl 05Feb2015 2015 doi:10.2903/j.efsa.2015.4001
+Pyraflufen-ethyl 603-347-1 129630-19-9 single chemical entity Component is identical to the substance Pyraflufen-ethyl 603-347-1 129630-19-9 ethyl 2-[2-chloro-5-[4-chloro-5-(difluoromethoxy)-1-methylpyrazol-3-yl]-4-fluorophenoxy]acetate Pyraflufen-ethyl C15H13Cl2F3N2O4 CCOC(=O)COC1=C(C=C(C(=C1)C2=NN(C(=C2Cl)OC(F)F)C)F)Cl InChI=1S/C15H13Cl2F3N2O4/c1-3-24-11(23)6-25-10-4-7(9(18)5-8(10)16)13-12(17)14(22(2)21-13)26-15(19)20/h4-5,15H,3,6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The Netherlands Pyraflufen-ethyl (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyraflufen-ethyl 05Feb2015 2015 doi:10.2903/j.efsa.2015.4001
+Pyraflufen-ethyl 603-347-1 129630-19-9 single chemical entity Component is identical to the substance Pyraflufen-ethyl 603-347-1 129630-19-9 ethyl 2-[2-chloro-5-[4-chloro-5-(difluoromethoxy)-1-methylpyrazol-3-yl]-4-fluorophenoxy]acetate Pyraflufen-ethyl C15H13Cl2F3N2O4 CCOC(=O)COC1=C(C=C(C(=C1)C2=NN(C(=C2Cl)OC(F)F)C)F)Cl InChI=1S/C15H13Cl2F3N2O4/c1-3-24-11(23)6-25-10-4-7(9(18)5-8(10)16)13-12(17)14(22(2)21-13)26-15(19)20/h4-5,15H,3,6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The Netherlands Pyraflufen-ethyl (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyraflufen-ethyl 05Feb2015 2015 doi:10.2903/j.efsa.2015.4001
+Pyraflufen-ethyl 603-347-1 129630-19-9 single chemical entity Component is identical to the substance Pyraflufen-ethyl 603-347-1 129630-19-9 ethyl 2-[2-chloro-5-[4-chloro-5-(difluoromethoxy)-1-methylpyrazol-3-yl]-4-fluorophenoxy]acetate Pyraflufen-ethyl C15H13Cl2F3N2O4 CCOC(=O)COC1=C(C=C(C(=C1)C2=NN(C(=C2Cl)OC(F)F)C)F)Cl InChI=1S/C15H13Cl2F3N2O4/c1-3-24-11(23)6-25-10-4-7(9(18)5-8(10)16)13-12(17)14(22(2)21-13)26-15(19)20/h4-5,15H,3,6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The Netherlands Pyraflufen-ethyl (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyraflufen-ethyl 05Feb2015 2015 doi:10.2903/j.efsa.2015.4001
+Pyraflufen-ethyl 603-347-1 129630-19-9 single chemical entity Component is identical to the substance Pyraflufen-ethyl 603-347-1 129630-19-9 ethyl 2-[2-chloro-5-[4-chloro-5-(difluoromethoxy)-1-methylpyrazol-3-yl]-4-fluorophenoxy]acetate Pyraflufen-ethyl C15H13Cl2F3N2O4 CCOC(=O)COC1=C(C=C(C(=C1)C2=NN(C(=C2Cl)OC(F)F)C)F)Cl InChI=1S/C15H13Cl2F3N2O4/c1-3-24-11(23)6-25-10-4-7(9(18)5-8(10)16)13-12(17)14(22(2)21-13)26-15(19)20/h4-5,15H,3,6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The Netherlands Pyraflufen-ethyl (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyraflufen-ethyl 05Feb2015 2015 doi:10.2903/j.efsa.2015.4001
+Pyraflufen-ethyl 603-347-1 129630-19-9 single chemical entity Component is identical to the substance Pyraflufen-ethyl 603-347-1 129630-19-9 ethyl 2-[2-chloro-5-[4-chloro-5-(difluoromethoxy)-1-methylpyrazol-3-yl]-4-fluorophenoxy]acetate Pyraflufen-ethyl C15H13Cl2F3N2O4 CCOC(=O)COC1=C(C=C(C(=C1)C2=NN(C(=C2Cl)OC(F)F)C)F)Cl InChI=1S/C15H13Cl2F3N2O4/c1-3-24-11(23)6-25-10-4-7(9(18)5-8(10)16)13-12(17)14(22(2)21-13)26-15(19)20/h4-5,15H,3,6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The Netherlands Pyraflufen-ethyl (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyraflufen-ethyl 05Feb2015 2015 doi:10.2903/j.efsa.2015.4001
+Pyraflufen-ethyl 603-347-1 129630-19-9 single chemical entity Component is identical to the substance Pyraflufen-ethyl 603-347-1 129630-19-9 ethyl 2-[2-chloro-5-[4-chloro-5-(difluoromethoxy)-1-methylpyrazol-3-yl]-4-fluorophenoxy]acetate Pyraflufen-ethyl C15H13Cl2F3N2O4 CCOC(=O)COC1=C(C=C(C(=C1)C2=NN(C(=C2Cl)OC(F)F)C)F)Cl InChI=1S/C15H13Cl2F3N2O4/c1-3-24-11(23)6-25-10-4-7(9(18)5-8(10)16)13-12(17)14(22(2)21-13)26-15(19)20/h4-5,15H,3,6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The Netherlands Pyraflufen-ethyl (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyraflufen-ethyl 05Feb2015 2015 doi:10.2903/j.efsa.2015.4001
+Pyraflufen-ethyl 603-347-1 129630-19-9 single chemical entity Component is identical to the substance Pyraflufen-ethyl 603-347-1 129630-19-9 ethyl 2-[2-chloro-5-[4-chloro-5-(difluoromethoxy)-1-methylpyrazol-3-yl]-4-fluorophenoxy]acetate Pyraflufen-ethyl C15H13Cl2F3N2O4 CCOC(=O)COC1=C(C=C(C(=C1)C2=NN(C(=C2Cl)OC(F)F)C)F)Cl InChI=1S/C15H13Cl2F3N2O4/c1-3-24-11(23)6-25-10-4-7(9(18)5-8(10)16)13-12(17)14(22(2)21-13)26-15(19)20/h4-5,15H,3,6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The Netherlands Pyraflufen-ethyl (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyraflufen-ethyl 05Feb2015 2015 doi:10.2903/j.efsa.2015.4001
+Pyraflufen-ethyl 603-347-1 129630-19-9 single chemical entity Component is identical to the substance Pyraflufen-ethyl 603-347-1 129630-19-9 ethyl 2-[2-chloro-5-[4-chloro-5-(difluoromethoxy)-1-methylpyrazol-3-yl]-4-fluorophenoxy]acetate Pyraflufen-ethyl C15H13Cl2F3N2O4 CCOC(=O)COC1=C(C=C(C(=C1)C2=NN(C(=C2Cl)OC(F)F)C)F)Cl InChI=1S/C15H13Cl2F3N2O4/c1-3-24-11(23)6-25-10-4-7(9(18)5-8(10)16)13-12(17)14(22(2)21-13)26-15(19)20/h4-5,15H,3,6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The Netherlands Pyraflufen-ethyl (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyraflufen-ethyl 05Feb2015 2015 doi:10.2903/j.efsa.2015.4001
+Pyraflufen-ethyl 603-347-1 129630-19-9 single chemical entity Component is identical to the substance Pyraflufen-ethyl 603-347-1 129630-19-9 ethyl 2-[2-chloro-5-[4-chloro-5-(difluoromethoxy)-1-methylpyrazol-3-yl]-4-fluorophenoxy]acetate Pyraflufen-ethyl C15H13Cl2F3N2O4 CCOC(=O)COC1=C(C=C(C(=C1)C2=NN(C(=C2Cl)OC(F)F)C)F)Cl InChI=1S/C15H13Cl2F3N2O4/c1-3-24-11(23)6-25-10-4-7(9(18)5-8(10)16)13-12(17)14(22(2)21-13)26-15(19)20/h4-5,15H,3,6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Positive no information RMS: The Netherlands Pyraflufen-ethyl (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyraflufen-ethyl 05Feb2015 2015 doi:10.2903/j.efsa.2015.4001
+Pyraflufen-ethyl 603-347-1 129630-19-9 single chemical entity Component is identical to the substance Pyraflufen-ethyl 603-347-1 129630-19-9 ethyl 2-[2-chloro-5-[4-chloro-5-(difluoromethoxy)-1-methylpyrazol-3-yl]-4-fluorophenoxy]acetate Pyraflufen-ethyl C15H13Cl2F3N2O4 CCOC(=O)COC1=C(C=C(C(=C1)C2=NN(C(=C2Cl)OC(F)F)C)F)Cl InChI=1S/C15H13Cl2F3N2O4/c1-3-24-11(23)6-25-10-4-7(9(18)5-8(10)16)13-12(17)14(22(2)21-13)26-15(19)20/h4-5,15H,3,6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: The Netherlands Pyraflufen-ethyl (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyraflufen-ethyl 05Feb2015 2015 doi:10.2903/j.efsa.2015.4001
+Pyraflufen-ethyl 603-347-1 129630-19-9 single chemical entity Component is identical to the substance Pyraflufen-ethyl 603-347-1 129630-19-9 ethyl 2-[2-chloro-5-[4-chloro-5-(difluoromethoxy)-1-methylpyrazol-3-yl]-4-fluorophenoxy]acetate Pyraflufen-ethyl C15H13Cl2F3N2O4 CCOC(=O)COC1=C(C=C(C(=C1)C2=NN(C(=C2Cl)OC(F)F)C)F)Cl InChI=1S/C15H13Cl2F3N2O4/c1-3-24-11(23)6-25-10-4-7(9(18)5-8(10)16)13-12(17)14(22(2)21-13)26-15(19)20/h4-5,15H,3,6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: The Netherlands Pyraflufen-ethyl (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyraflufen-ethyl 05Feb2015 2015 doi:10.2903/j.efsa.2015.4001
+Pyraflufen-ethyl 603-347-1 129630-19-9 single chemical entity Component is identical to the substance Pyraflufen-ethyl 603-347-1 129630-19-9 ethyl 2-[2-chloro-5-[4-chloro-5-(difluoromethoxy)-1-methylpyrazol-3-yl]-4-fluorophenoxy]acetate Pyraflufen-ethyl C15H13Cl2F3N2O4 CCOC(=O)COC1=C(C=C(C(=C1)C2=NN(C(=C2Cl)OC(F)F)C)F)Cl InChI=1S/C15H13Cl2F3N2O4/c1-3-24-11(23)6-25-10-4-7(9(18)5-8(10)16)13-12(17)14(22(2)21-13)26-15(19)20/h4-5,15H,3,6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: The Netherlands Pyraflufen-ethyl (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyraflufen-ethyl 05Feb2015 2015 doi:10.2903/j.efsa.2015.4001
+Pyraflufen-ethyl 603-347-1 129630-19-9 single chemical entity Component is identical to the substance Pyraflufen-ethyl 603-347-1 129630-19-9 ethyl 2-[2-chloro-5-[4-chloro-5-(difluoromethoxy)-1-methylpyrazol-3-yl]-4-fluorophenoxy]acetate Pyraflufen-ethyl C15H13Cl2F3N2O4 CCOC(=O)COC1=C(C=C(C(=C1)C2=NN(C(=C2Cl)OC(F)F)C)F)Cl InChI=1S/C15H13Cl2F3N2O4/c1-3-24-11(23)6-25-10-4-7(9(18)5-8(10)16)13-12(17)14(22(2)21-13)26-15(19)20/h4-5,15H,3,6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Pyraflufen-ethyl (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyraflufen-ethyl 05Feb2015 2015 doi:10.2903/j.efsa.2015.4001
+Pyraflufen-ethyl 603-347-1 129630-19-9 single chemical entity Component is identical to the substance Pyraflufen-ethyl 603-347-1 129630-19-9 ethyl 2-[2-chloro-5-[4-chloro-5-(difluoromethoxy)-1-methylpyrazol-3-yl]-4-fluorophenoxy]acetate Pyraflufen-ethyl C15H13Cl2F3N2O4 CCOC(=O)COC1=C(C=C(C(=C1)C2=NN(C(=C2Cl)OC(F)F)C)F)Cl InChI=1S/C15H13Cl2F3N2O4/c1-3-24-11(23)6-25-10-4-7(9(18)5-8(10)16)13-12(17)14(22(2)21-13)26-15(19)20/h4-5,15H,3,6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Pyraflufen-ethyl (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyraflufen-ethyl 05Feb2015 2015 doi:10.2903/j.efsa.2015.4001
+Pyraflufen-ethyl 603-347-1 129630-19-9 single chemical entity Component is identical to the substance Pyraflufen-ethyl 603-347-1 129630-19-9 ethyl 2-[2-chloro-5-[4-chloro-5-(difluoromethoxy)-1-methylpyrazol-3-yl]-4-fluorophenoxy]acetate Pyraflufen-ethyl C15H13Cl2F3N2O4 CCOC(=O)COC1=C(C=C(C(=C1)C2=NN(C(=C2Cl)OC(F)F)C)F)Cl InChI=1S/C15H13Cl2F3N2O4/c1-3-24-11(23)6-25-10-4-7(9(18)5-8(10)16)13-12(17)14(22(2)21-13)26-15(19)20/h4-5,15H,3,6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Pyraflufen-ethyl (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyraflufen-ethyl 05Feb2015 2015 doi:10.2903/j.efsa.2015.4001
+Pyraflufen-ethyl 603-347-1 129630-19-9 single chemical entity Component is identical to the substance Pyraflufen-ethyl 603-347-1 129630-19-9 ethyl 2-[2-chloro-5-[4-chloro-5-(difluoromethoxy)-1-methylpyrazol-3-yl]-4-fluorophenoxy]acetate Pyraflufen-ethyl C15H13Cl2F3N2O4 CCOC(=O)COC1=C(C=C(C(=C1)C2=NN(C(=C2Cl)OC(F)F)C)F)Cl InChI=1S/C15H13Cl2F3N2O4/c1-3-24-11(23)6-25-10-4-7(9(18)5-8(10)16)13-12(17)14(22(2)21-13)26-15(19)20/h4-5,15H,3,6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Pyraflufen-ethyl (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyraflufen-ethyl 05Feb2015 2015 doi:10.2903/j.efsa.2015.4001
+Pyraflufen-ethyl 603-347-1 129630-19-9 single chemical entity Component is identical to the substance Pyraflufen-ethyl 603-347-1 129630-19-9 ethyl 2-[2-chloro-5-[4-chloro-5-(difluoromethoxy)-1-methylpyrazol-3-yl]-4-fluorophenoxy]acetate Pyraflufen-ethyl C15H13Cl2F3N2O4 CCOC(=O)COC1=C(C=C(C(=C1)C2=NN(C(=C2Cl)OC(F)F)C)F)Cl InChI=1S/C15H13Cl2F3N2O4/c1-3-24-11(23)6-25-10-4-7(9(18)5-8(10)16)13-12(17)14(22(2)21-13)26-15(19)20/h4-5,15H,3,6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Pyraflufen-ethyl (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyraflufen-ethyl 05Feb2015 2015 doi:10.2903/j.efsa.2015.4001
+Pyraflufen-ethyl 603-347-1 129630-19-9 single chemical entity Component is identical to the substance Pyraflufen-ethyl 603-347-1 129630-19-9 ethyl 2-[2-chloro-5-[4-chloro-5-(difluoromethoxy)-1-methylpyrazol-3-yl]-4-fluorophenoxy]acetate Pyraflufen-ethyl C15H13Cl2F3N2O4 CCOC(=O)COC1=C(C=C(C(=C1)C2=NN(C(=C2Cl)OC(F)F)C)F)Cl InChI=1S/C15H13Cl2F3N2O4/c1-3-24-11(23)6-25-10-4-7(9(18)5-8(10)16)13-12(17)14(22(2)21-13)26-15(19)20/h4-5,15H,3,6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Pyraflufen-ethyl (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyraflufen-ethyl 05Feb2015 2015 doi:10.2903/j.efsa.2015.4001
+Pyraflufen-ethyl 603-347-1 129630-19-9 single chemical entity Component is identical to the substance Pyraflufen-ethyl 603-347-1 129630-19-9 ethyl 2-[2-chloro-5-[4-chloro-5-(difluoromethoxy)-1-methylpyrazol-3-yl]-4-fluorophenoxy]acetate Pyraflufen-ethyl C15H13Cl2F3N2O4 CCOC(=O)COC1=C(C=C(C(=C1)C2=NN(C(=C2Cl)OC(F)F)C)F)Cl InChI=1S/C15H13Cl2F3N2O4/c1-3-24-11(23)6-25-10-4-7(9(18)5-8(10)16)13-12(17)14(22(2)21-13)26-15(19)20/h4-5,15H,3,6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Not reported 10 Male/Female oral: gavage 72.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: The Netherlands Pyraflufen-ethyl (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyraflufen-ethyl 05Feb2015 2015 doi:10.2903/j.efsa.2015.4001
+Pyraflufen-ethyl 603-347-1 129630-19-9 single chemical entity Component is identical to the substance Pyraflufen-ethyl 603-347-1 129630-19-9 ethyl 2-[2-chloro-5-[4-chloro-5-(difluoromethoxy)-1-methylpyrazol-3-yl]-4-fluorophenoxy]acetate Pyraflufen-ethyl C15H13Cl2F3N2O4 CCOC(=O)COC1=C(C=C(C(=C1)C2=NN(C(=C2Cl)OC(F)F)C)F)Cl InChI=1S/C15H13Cl2F3N2O4/c1-3-24-11(23)6-25-10-4-7(9(18)5-8(10)16)13-12(17)14(22(2)21-13)26-15(19)20/h4-5,15H,3,6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Not reported 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: The Netherlands Pyraflufen-ethyl (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyraflufen-ethyl 05Feb2015 2015 doi:10.2903/j.efsa.2015.4001
+Pyraflufen-ethyl 603-347-1 129630-19-9 single chemical entity Component is identical to the substance Pyraflufen-ethyl 603-347-1 129630-19-9 ethyl 2-[2-chloro-5-[4-chloro-5-(difluoromethoxy)-1-methylpyrazol-3-yl]-4-fluorophenoxy]acetate Pyraflufen-ethyl C15H13Cl2F3N2O4 CCOC(=O)COC1=C(C=C(C(=C1)C2=NN(C(=C2Cl)OC(F)F)C)F)Cl InChI=1S/C15H13Cl2F3N2O4/c1-3-24-11(23)6-25-10-4-7(9(18)5-8(10)16)13-12(17)14(22(2)21-13)26-15(19)20/h4-5,15H,3,6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Not reported 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: The Netherlands Pyraflufen-ethyl (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyraflufen-ethyl 05Feb2015 2015 doi:10.2903/j.efsa.2015.4001
+Pyraflufen-ethyl 603-347-1 129630-19-9 single chemical entity Component is identical to the substance Pyraflufen-ethyl 603-347-1 129630-19-9 ethyl 2-[2-chloro-5-[4-chloro-5-(difluoromethoxy)-1-methylpyrazol-3-yl]-4-fluorophenoxy]acetate Pyraflufen-ethyl C15H13Cl2F3N2O4 CCOC(=O)COC1=C(C=C(C(=C1)C2=NN(C(=C2Cl)OC(F)F)C)F)Cl InChI=1S/C15H13Cl2F3N2O4/c1-3-24-11(23)6-25-10-4-7(9(18)5-8(10)16)13-12(17)14(22(2)21-13)26-15(19)20/h4-5,15H,3,6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Sprague-Dawley 4 Male oral: unspecified 14.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The Netherlands Pyraflufen-ethyl (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyraflufen-ethyl 05Feb2015 2015 doi:10.2903/j.efsa.2015.4001
+Pyraflufen-ethyl 603-347-1 129630-19-9 single chemical entity Component is identical to the substance Pyraflufen-ethyl 603-347-1 129630-19-9 ethyl 2-[2-chloro-5-[4-chloro-5-(difluoromethoxy)-1-methylpyrazol-3-yl]-4-fluorophenoxy]acetate Pyraflufen-ethyl C15H13Cl2F3N2O4 CCOC(=O)COC1=C(C=C(C(=C1)C2=NN(C(=C2Cl)OC(F)F)C)F)Cl InChI=1S/C15H13Cl2F3N2O4/c1-3-24-11(23)6-25-10-4-7(9(18)5-8(10)16)13-12(17)14(22(2)21-13)26-15(19)20/h4-5,15H,3,6H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Sprague-Dawley 4 Male oral: unspecified 2.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The Netherlands Pyraflufen-ethyl (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyraflufen-ethyl 05Feb2015 2015 doi:10.2903/j.efsa.2015.4001
+Methomyl 240-815-0 16752-77-5 single chemical entity Component is identical to the substance Methomyl 240-815-0 16752-77-5 methyl N-[(methylcarbamoyl)oxy]ethanimidothioate Methomyl C5H10N2O2S CSC(C)=NOC(NC)=O InChI=1S/C5H10N2O2S/c1-4(10-3)7-9-5(8)6-2/h1-3H3,(H,6,8)/b7-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Methomyl 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance methomyl 06Apr2009 2009 doi:10.2903/j.efsa.2009.222r
+Methomyl 240-815-0 16752-77-5 single chemical entity Component is identical to the substance Methomyl 240-815-0 16752-77-5 methyl N-[(methylcarbamoyl)oxy]ethanimidothioate Methomyl C5H10N2O2S CSC(C)=NOC(NC)=O InChI=1S/C5H10N2O2S/c1-4(10-3)7-9-5(8)6-2/h1-3H3,(H,6,8)/b7-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Methomyl 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance methomyl 06Apr2009 2009 doi:10.2903/j.efsa.2009.222r
+Methomyl 240-815-0 16752-77-5 single chemical entity Component is identical to the substance Methomyl 240-815-0 16752-77-5 methyl N-[(methylcarbamoyl)oxy]ethanimidothioate Methomyl C5H10N2O2S CSC(C)=NOC(NC)=O InChI=1S/C5H10N2O2S/c1-4(10-3)7-9-5(8)6-2/h1-3H3,(H,6,8)/b7-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Methomyl 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance methomyl 06Apr2009 2009 doi:10.2903/j.efsa.2009.222r
+Methomyl 240-815-0 16752-77-5 single chemical entity Component is identical to the substance Methomyl 240-815-0 16752-77-5 methyl N-[(methylcarbamoyl)oxy]ethanimidothioate Methomyl C5H10N2O2S CSC(C)=NOC(NC)=O InChI=1S/C5H10N2O2S/c1-4(10-3)7-9-5(8)6-2/h1-3H3,(H,6,8)/b7-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Methomyl 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance methomyl 06Apr2009 2009 doi:10.2903/j.efsa.2009.222r
+Methomyl 240-815-0 16752-77-5 single chemical entity Component is identical to the substance Methomyl 240-815-0 16752-77-5 methyl N-[(methylcarbamoyl)oxy]ethanimidothioate Methomyl C5H10N2O2S CSC(C)=NOC(NC)=O InChI=1S/C5H10N2O2S/c1-4(10-3)7-9-5(8)6-2/h1-3H3,(H,6,8)/b7-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Methomyl 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance methomyl 06Apr2009 2009 doi:10.2903/j.efsa.2009.222r
+Methomyl 240-815-0 16752-77-5 single chemical entity Component is identical to the substance Methomyl 240-815-0 16752-77-5 methyl N-[(methylcarbamoyl)oxy]ethanimidothioate Methomyl C5H10N2O2S CSC(C)=NOC(NC)=O InChI=1S/C5H10N2O2S/c1-4(10-3)7-9-5(8)6-2/h1-3H3,(H,6,8)/b7-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Methomyl 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance methomyl 06Apr2009 2009 doi:10.2903/j.efsa.2009.222r
+Methomyl 240-815-0 16752-77-5 single chemical entity Component is identical to the substance Methomyl 240-815-0 16752-77-5 methyl N-[(methylcarbamoyl)oxy]ethanimidothioate Methomyl C5H10N2O2S CSC(C)=NOC(NC)=O InChI=1S/C5H10N2O2S/c1-4(10-3)7-9-5(8)6-2/h1-3H3,(H,6,8)/b7-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Methomyl 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance methomyl 06Apr2009 2009 doi:10.2903/j.efsa.2009.222r
+Methomyl 240-815-0 16752-77-5 single chemical entity Component is identical to the substance Methomyl 240-815-0 16752-77-5 methyl N-[(methylcarbamoyl)oxy]ethanimidothioate Methomyl C5H10N2O2S CSC(C)=NOC(NC)=O InChI=1S/C5H10N2O2S/c1-4(10-3)7-9-5(8)6-2/h1-3H3,(H,6,8)/b7-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Methomyl 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance methomyl 06Apr2009 2009 doi:10.2903/j.efsa.2009.222r
+Methomyl 240-815-0 16752-77-5 single chemical entity Component is identical to the substance Methomyl 240-815-0 16752-77-5 methyl N-[(methylcarbamoyl)oxy]ethanimidothioate Methomyl C5H10N2O2S CSC(C)=NOC(NC)=O InChI=1S/C5H10N2O2S/c1-4(10-3)7-9-5(8)6-2/h1-3H3,(H,6,8)/b7-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Methomyl 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance methomyl 06Apr2009 2009 doi:10.2903/j.efsa.2009.222r
+Methomyl 240-815-0 16752-77-5 single chemical entity Component is identical to the substance Methomyl 240-815-0 16752-77-5 methyl N-[(methylcarbamoyl)oxy]ethanimidothioate Methomyl C5H10N2O2S CSC(C)=NOC(NC)=O InChI=1S/C5H10N2O2S/c1-4(10-3)7-9-5(8)6-2/h1-3H3,(H,6,8)/b7-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Methomyl 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance methomyl 06Apr2009 2009 doi:10.2903/j.efsa.2009.222r
+Methomyl 240-815-0 16752-77-5 single chemical entity Component is identical to the substance Methomyl 240-815-0 16752-77-5 methyl N-[(methylcarbamoyl)oxy]ethanimidothioate Methomyl C5H10N2O2S CSC(C)=NOC(NC)=O InChI=1S/C5H10N2O2S/c1-4(10-3)7-9-5(8)6-2/h1-3H3,(H,6,8)/b7-4- organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Methomyl 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance methomyl 06Apr2009 2009 doi:10.2903/j.efsa.2009.222r
+Methomyl 240-815-0 16752-77-5 single chemical entity Component is identical to the substance Methomyl 240-815-0 16752-77-5 methyl N-[(methylcarbamoyl)oxy]ethanimidothioate Methomyl C5H10N2O2S CSC(C)=NOC(NC)=O InChI=1S/C5H10N2O2S/c1-4(10-3)7-9-5(8)6-2/h1-3H3,(H,6,8)/b7-4- organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Methomyl 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance methomyl 06Apr2009 2009 doi:10.2903/j.efsa.2009.222r
+Methomyl 240-815-0 16752-77-5 single chemical entity Component is identical to the substance Methomyl 240-815-0 16752-77-5 methyl N-[(methylcarbamoyl)oxy]ethanimidothioate Methomyl C5H10N2O2S CSC(C)=NOC(NC)=O InChI=1S/C5H10N2O2S/c1-4(10-3)7-9-5(8)6-2/h1-3H3,(H,6,8)/b7-4- organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Methomyl 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance methomyl 06Apr2009 2009 doi:10.2903/j.efsa.2009.222r
+Methomyl 240-815-0 16752-77-5 single chemical entity Component is identical to the substance Methomyl 240-815-0 16752-77-5 methyl N-[(methylcarbamoyl)oxy]ethanimidothioate Methomyl C5H10N2O2S CSC(C)=NOC(NC)=O InChI=1S/C5H10N2O2S/c1-4(10-3)7-9-5(8)6-2/h1-3H3,(H,6,8)/b7-4- organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Rat (as animal) Sprague-Dawley 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Methomyl 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance methomyl 06Apr2009 2009 doi:10.2903/j.efsa.2009.222r
+Methomyl 240-815-0 16752-77-5 single chemical entity Component is identical to the substance Methomyl 240-815-0 16752-77-5 methyl N-[(methylcarbamoyl)oxy]ethanimidothioate Methomyl C5H10N2O2S CSC(C)=NOC(NC)=O InChI=1S/C5H10N2O2S/c1-4(10-3)7-9-5(8)6-2/h1-3H3,(H,6,8)/b7-4- organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Rat (as animal) Sprague-Dawley 10 Male/Female oral: gavage 6.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Methomyl 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance methomyl 06Apr2009 2009 doi:10.2903/j.efsa.2009.222r
+Methomyl 240-815-0 16752-77-5 single chemical entity Component is identical to the substance Methomyl 240-815-0 16752-77-5 methyl N-[(methylcarbamoyl)oxy]ethanimidothioate Methomyl C5H10N2O2S CSC(C)=NOC(NC)=O InChI=1S/C5H10N2O2S/c1-4(10-3)7-9-5(8)6-2/h1-3H3,(H,6,8)/b7-4- organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Rat (as animal) Sprague-Dawley 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Methomyl 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance methomyl 06Apr2009 2009 doi:10.2903/j.efsa.2009.222r
+Methomyl 240-815-0 16752-77-5 single chemical entity Component is identical to the substance Methomyl 240-815-0 16752-77-5 methyl N-[(methylcarbamoyl)oxy]ethanimidothioate Methomyl C5H10N2O2S CSC(C)=NOC(NC)=O InChI=1S/C5H10N2O2S/c1-4(10-3)7-9-5(8)6-2/h1-3H3,(H,6,8)/b7-4- organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) ICR 10 Male/Female oral: gavage 24.0000000000 h yes not applicable Negative no evidence RMS: The United Kingdom Methomyl 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance methomyl 06Apr2009 2009 doi:10.2903/j.efsa.2009.222r
+Methomyl 240-815-0 16752-77-5 single chemical entity Component is identical to the substance Methomyl 240-815-0 16752-77-5 methyl N-[(methylcarbamoyl)oxy]ethanimidothioate Methomyl C5H10N2O2S CSC(C)=NOC(NC)=O InChI=1S/C5H10N2O2S/c1-4(10-3)7-9-5(8)6-2/h1-3H3,(H,6,8)/b7-4- organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) ICR 10 Male/Female oral: gavage 72.0000000000 h yes not applicable Negative no evidence RMS: The United Kingdom Methomyl 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance methomyl 06Apr2009 2009 doi:10.2903/j.efsa.2009.222r
+Methomyl 240-815-0 16752-77-5 single chemical entity Component is identical to the substance Methomyl 240-815-0 16752-77-5 methyl N-[(methylcarbamoyl)oxy]ethanimidothioate Methomyl C5H10N2O2S CSC(C)=NOC(NC)=O InChI=1S/C5H10N2O2S/c1-4(10-3)7-9-5(8)6-2/h1-3H3,(H,6,8)/b7-4- organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) ICR 10 Male/Female oral: gavage 48.0000000000 h yes not applicable Negative no evidence RMS: The United Kingdom Methomyl 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance methomyl 06Apr2009 2009 doi:10.2903/j.efsa.2009.222r
+Methomyl 240-815-0 16752-77-5 single chemical entity Component is identical to the substance Methomyl 240-815-0 16752-77-5 methyl N-[(methylcarbamoyl)oxy]ethanimidothioate Methomyl C5H10N2O2S CSC(C)=NOC(NC)=O InChI=1S/C5H10N2O2S/c1-4(10-3)7-9-5(8)6-2/h1-3H3,(H,6,8)/b7-4- organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Methomyl (Addendum 1) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance methomyl 06Apr2009 2009 doi:10.2903/j.efsa.2009.222r
+Methomyl 240-815-0 16752-77-5 single chemical entity Component is identical to the substance Methomyl 240-815-0 16752-77-5 methyl N-[(methylcarbamoyl)oxy]ethanimidothioate Methomyl C5H10N2O2S CSC(C)=NOC(NC)=O InChI=1S/C5H10N2O2S/c1-4(10-3)7-9-5(8)6-2/h1-3H3,(H,6,8)/b7-4- organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Methomyl (Addendum 1) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance methomyl 06Apr2009 2009 doi:10.2903/j.efsa.2009.222r
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Positive RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Positive RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Positive RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Positive RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Positive RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Metrafenone 220899-03-6 single chemical entity Component is identical to the substance Metrafenone 220899-03-6 (3-Bromo-6-methoxy-2-methylphenyl)-(2,3,4-trimethoxy-6-methylphenyl)methanone Metrafenone C19H21BrO5 CC1=CC(=C(C(=C1C(=O)C2=C(C=CC(=C2C)Br)OC)OC)OC)OC InChI=1S/C19H21BrO5/c1-10-9-14(23-4)18(24-5)19(25-6)15(10)17(21)16-11(2)12(20)7-8-13(16)22-3/h7-9H,1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metrafenone 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metrafenone 01Feb2006 2006 doi:10.2903/j.efsa.2006.58r
+Metrafenone 220899-03-6 single chemical entity Component is identical to the substance Metrafenone 220899-03-6 (3-Bromo-6-methoxy-2-methylphenyl)-(2,3,4-trimethoxy-6-methylphenyl)methanone Metrafenone C19H21BrO5 CC1=CC(=C(C(=C1C(=O)C2=C(C=CC(=C2C)Br)OC)OC)OC)OC InChI=1S/C19H21BrO5/c1-10-9-14(23-4)18(24-5)19(25-6)15(10)17(21)16-11(2)12(20)7-8-13(16)22-3/h7-9H,1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metrafenone 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metrafenone 01Feb2006 2006 doi:10.2903/j.efsa.2006.58r
+Metrafenone 220899-03-6 single chemical entity Component is identical to the substance Metrafenone 220899-03-6 (3-Bromo-6-methoxy-2-methylphenyl)-(2,3,4-trimethoxy-6-methylphenyl)methanone Metrafenone C19H21BrO5 CC1=CC(=C(C(=C1C(=O)C2=C(C=CC(=C2C)Br)OC)OC)OC)OC InChI=1S/C19H21BrO5/c1-10-9-14(23-4)18(24-5)19(25-6)15(10)17(21)16-11(2)12(20)7-8-13(16)22-3/h7-9H,1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metrafenone 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metrafenone 01Feb2006 2006 doi:10.2903/j.efsa.2006.58r
+Metrafenone 220899-03-6 single chemical entity Component is identical to the substance Metrafenone 220899-03-6 (3-Bromo-6-methoxy-2-methylphenyl)-(2,3,4-trimethoxy-6-methylphenyl)methanone Metrafenone C19H21BrO5 CC1=CC(=C(C(=C1C(=O)C2=C(C=CC(=C2C)Br)OC)OC)OC)OC InChI=1S/C19H21BrO5/c1-10-9-14(23-4)18(24-5)19(25-6)15(10)17(21)16-11(2)12(20)7-8-13(16)22-3/h7-9H,1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metrafenone 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metrafenone 01Feb2006 2006 doi:10.2903/j.efsa.2006.58r
+Metrafenone 220899-03-6 single chemical entity Component is identical to the substance Metrafenone 220899-03-6 (3-Bromo-6-methoxy-2-methylphenyl)-(2,3,4-trimethoxy-6-methylphenyl)methanone Metrafenone C19H21BrO5 CC1=CC(=C(C(=C1C(=O)C2=C(C=CC(=C2C)Br)OC)OC)OC)OC InChI=1S/C19H21BrO5/c1-10-9-14(23-4)18(24-5)19(25-6)15(10)17(21)16-11(2)12(20)7-8-13(16)22-3/h7-9H,1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metrafenone 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metrafenone 01Feb2006 2006 doi:10.2903/j.efsa.2006.58r
+Metrafenone 220899-03-6 single chemical entity Component is identical to the substance Metrafenone 220899-03-6 (3-Bromo-6-methoxy-2-methylphenyl)-(2,3,4-trimethoxy-6-methylphenyl)methanone Metrafenone C19H21BrO5 CC1=CC(=C(C(=C1C(=O)C2=C(C=CC(=C2C)Br)OC)OC)OC)OC InChI=1S/C19H21BrO5/c1-10-9-14(23-4)18(24-5)19(25-6)15(10)17(21)16-11(2)12(20)7-8-13(16)22-3/h7-9H,1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metrafenone 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metrafenone 01Feb2006 2006 doi:10.2903/j.efsa.2006.58r
+Metrafenone 220899-03-6 single chemical entity Component is identical to the substance Metrafenone 220899-03-6 (3-Bromo-6-methoxy-2-methylphenyl)-(2,3,4-trimethoxy-6-methylphenyl)methanone Metrafenone C19H21BrO5 CC1=CC(=C(C(=C1C(=O)C2=C(C=CC(=C2C)Br)OC)OC)OC)OC InChI=1S/C19H21BrO5/c1-10-9-14(23-4)18(24-5)19(25-6)15(10)17(21)16-11(2)12(20)7-8-13(16)22-3/h7-9H,1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metrafenone 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metrafenone 01Feb2006 2006 doi:10.2903/j.efsa.2006.58r
+Metrafenone 220899-03-6 single chemical entity Component is identical to the substance Metrafenone 220899-03-6 (3-Bromo-6-methoxy-2-methylphenyl)-(2,3,4-trimethoxy-6-methylphenyl)methanone Metrafenone C19H21BrO5 CC1=CC(=C(C(=C1C(=O)C2=C(C=CC(=C2C)Br)OC)OC)OC)OC InChI=1S/C19H21BrO5/c1-10-9-14(23-4)18(24-5)19(25-6)15(10)17(21)16-11(2)12(20)7-8-13(16)22-3/h7-9H,1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metrafenone 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metrafenone 01Feb2006 2006 doi:10.2903/j.efsa.2006.58r
+Metrafenone 220899-03-6 single chemical entity Component is identical to the substance Metrafenone 220899-03-6 (3-Bromo-6-methoxy-2-methylphenyl)-(2,3,4-trimethoxy-6-methylphenyl)methanone Metrafenone C19H21BrO5 CC1=CC(=C(C(=C1C(=O)C2=C(C=CC(=C2C)Br)OC)OC)OC)OC InChI=1S/C19H21BrO5/c1-10-9-14(23-4)18(24-5)19(25-6)15(10)17(21)16-11(2)12(20)7-8-13(16)22-3/h7-9H,1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metrafenone 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metrafenone 01Feb2006 2006 doi:10.2903/j.efsa.2006.58r
+Metrafenone 220899-03-6 single chemical entity Component is identical to the substance Metrafenone 220899-03-6 (3-Bromo-6-methoxy-2-methylphenyl)-(2,3,4-trimethoxy-6-methylphenyl)methanone Metrafenone C19H21BrO5 CC1=CC(=C(C(=C1C(=O)C2=C(C=CC(=C2C)Br)OC)OC)OC)OC InChI=1S/C19H21BrO5/c1-10-9-14(23-4)18(24-5)19(25-6)15(10)17(21)16-11(2)12(20)7-8-13(16)22-3/h7-9H,1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metrafenone 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metrafenone 01Feb2006 2006 doi:10.2903/j.efsa.2006.58r
+Metrafenone 220899-03-6 single chemical entity Component is identical to the substance Metrafenone 220899-03-6 (3-Bromo-6-methoxy-2-methylphenyl)-(2,3,4-trimethoxy-6-methylphenyl)methanone Metrafenone C19H21BrO5 CC1=CC(=C(C(=C1C(=O)C2=C(C=CC(=C2C)Br)OC)OC)OC)OC InChI=1S/C19H21BrO5/c1-10-9-14(23-4)18(24-5)19(25-6)15(10)17(21)16-11(2)12(20)7-8-13(16)22-3/h7-9H,1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metrafenone 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metrafenone 01Feb2006 2006 doi:10.2903/j.efsa.2006.58r
+Metrafenone 220899-03-6 single chemical entity Component is identical to the substance Metrafenone 220899-03-6 (3-Bromo-6-methoxy-2-methylphenyl)-(2,3,4-trimethoxy-6-methylphenyl)methanone Metrafenone C19H21BrO5 CC1=CC(=C(C(=C1C(=O)C2=C(C=CC(=C2C)Br)OC)OC)OC)OC InChI=1S/C19H21BrO5/c1-10-9-14(23-4)18(24-5)19(25-6)15(10)17(21)16-11(2)12(20)7-8-13(16)22-3/h7-9H,1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metrafenone 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metrafenone 01Feb2006 2006 doi:10.2903/j.efsa.2006.58r
+Metrafenone 220899-03-6 single chemical entity Component is identical to the substance Metrafenone 220899-03-6 (3-Bromo-6-methoxy-2-methylphenyl)-(2,3,4-trimethoxy-6-methylphenyl)methanone Metrafenone C19H21BrO5 CC1=CC(=C(C(=C1C(=O)C2=C(C=CC(=C2C)Br)OC)OC)OC)OC InChI=1S/C19H21BrO5/c1-10-9-14(23-4)18(24-5)19(25-6)15(10)17(21)16-11(2)12(20)7-8-13(16)22-3/h7-9H,1-6H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported no data without Negative RMS: The United Kingdom Metrafenone 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metrafenone 01Feb2006 2006 doi:10.2903/j.efsa.2006.58r
+Metrafenone 220899-03-6 single chemical entity Component is identical to the substance Metrafenone 220899-03-6 (3-Bromo-6-methoxy-2-methylphenyl)-(2,3,4-trimethoxy-6-methylphenyl)methanone Metrafenone C19H21BrO5 CC1=CC(=C(C(=C1C(=O)C2=C(C=CC(=C2C)Br)OC)OC)OC)OC InChI=1S/C19H21BrO5/c1-10-9-14(23-4)18(24-5)19(25-6)15(10)17(21)16-11(2)12(20)7-8-13(16)22-3/h7-9H,1-6H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported no data with Negative RMS: The United Kingdom Metrafenone 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metrafenone 01Feb2006 2006 doi:10.2903/j.efsa.2006.58r
+Metrafenone 220899-03-6 single chemical entity Component is identical to the substance Metrafenone 220899-03-6 (3-Bromo-6-methoxy-2-methylphenyl)-(2,3,4-trimethoxy-6-methylphenyl)methanone Metrafenone C19H21BrO5 CC1=CC(=C(C(=C1C(=O)C2=C(C=CC(=C2C)Br)OC)OC)OC)OC InChI=1S/C19H21BrO5/c1-10-9-14(23-4)18(24-5)19(25-6)15(10)17(21)16-11(2)12(20)7-8-13(16)22-3/h7-9H,1-6H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect-toxicokinetic investigations RMS: The United Kingdom Metrafenone 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metrafenone 01Feb2006 2006 doi:10.2903/j.efsa.2006.58r
+Metrafenone 220899-03-6 single chemical entity Component is identical to the substance Metrafenone 220899-03-6 (3-Bromo-6-methoxy-2-methylphenyl)-(2,3,4-trimethoxy-6-methylphenyl)methanone Metrafenone C19H21BrO5 CC1=CC(=C(C(=C1C(=O)C2=C(C=CC(=C2C)Br)OC)OC)OC)OC InChI=1S/C19H21BrO5/c1-10-9-14(23-4)18(24-5)19(25-6)15(10)17(21)16-11(2)12(20)7-8-13(16)22-3/h7-9H,1-6H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 72.0000000000 h yes, concurrent vehicle not applicable Negative indirect-toxicokinetic investigations RMS: The United Kingdom Metrafenone 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metrafenone 01Feb2006 2006 doi:10.2903/j.efsa.2006.58r
+Metrafenone 220899-03-6 single chemical entity Component is identical to the substance Metrafenone 220899-03-6 (3-Bromo-6-methoxy-2-methylphenyl)-(2,3,4-trimethoxy-6-methylphenyl)methanone Metrafenone C19H21BrO5 CC1=CC(=C(C(=C1C(=O)C2=C(C=CC(=C2C)Br)OC)OC)OC)OC InChI=1S/C19H21BrO5/c1-10-9-14(23-4)18(24-5)19(25-6)15(10)17(21)16-11(2)12(20)7-8-13(16)22-3/h7-9H,1-6H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect-toxicokinetic investigations RMS: The United Kingdom Metrafenone 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metrafenone 01Feb2006 2006 doi:10.2903/j.efsa.2006.58r
+Prohexadione-calcium 127277-53-6 single chemical entity Component is identical to the substance Prohexadione-calcium 127277-53-6 Calcium;1-(4-carboxy-2,6-dioxocyclohexylidene)propan-1-olate Not in list C20H22CaO10 CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].[Ca+2] InChI=1S/2C10H12O5.Ca/c2*1-2-6(11)9-7(12)3-5(10(14)15)4-8(9)13;/h2*5,11H,2-4H2,1H3,(H,14,15);/q;;+2/p-2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: France Prohexadione-calcium 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prohexadione (considered variant prohexadione-calcium) 26Mar2010 2010 doi:10.2903/j.efsa.2010.1555
+Prohexadione-calcium 127277-53-6 single chemical entity Component is identical to the substance Prohexadione-calcium 127277-53-6 Calcium;1-(4-carboxy-2,6-dioxocyclohexylidene)propan-1-olate Not in list C20H22CaO10 CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].[Ca+2] InChI=1S/2C10H12O5.Ca/c2*1-2-6(11)9-7(12)3-5(10(14)15)4-8(9)13;/h2*5,11H,2-4H2,1H3,(H,14,15);/q;;+2/p-2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: France Prohexadione-calcium 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prohexadione (considered variant prohexadione-calcium) 26Mar2010 2010 doi:10.2903/j.efsa.2010.1555
+Prohexadione-calcium 127277-53-6 single chemical entity Component is identical to the substance Prohexadione-calcium 127277-53-6 Calcium;1-(4-carboxy-2,6-dioxocyclohexylidene)propan-1-olate Not in list C20H22CaO10 CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].[Ca+2] InChI=1S/2C10H12O5.Ca/c2*1-2-6(11)9-7(12)3-5(10(14)15)4-8(9)13;/h2*5,11H,2-4H2,1H3,(H,14,15);/q;;+2/p-2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: France Prohexadione-calcium 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prohexadione (considered variant prohexadione-calcium) 26Mar2010 2010 doi:10.2903/j.efsa.2010.1555
+Prohexadione-calcium 127277-53-6 single chemical entity Component is identical to the substance Prohexadione-calcium 127277-53-6 Calcium;1-(4-carboxy-2,6-dioxocyclohexylidene)propan-1-olate Not in list C20H22CaO10 CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].[Ca+2] InChI=1S/2C10H12O5.Ca/c2*1-2-6(11)9-7(12)3-5(10(14)15)4-8(9)13;/h2*5,11H,2-4H2,1H3,(H,14,15);/q;;+2/p-2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: France Prohexadione-calcium 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prohexadione (considered variant prohexadione-calcium) 26Mar2010 2010 doi:10.2903/j.efsa.2010.1555
+Prohexadione-calcium 127277-53-6 single chemical entity Component is identical to the substance Prohexadione-calcium 127277-53-6 Calcium;1-(4-carboxy-2,6-dioxocyclohexylidene)propan-1-olate Not in list C20H22CaO10 CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].[Ca+2] InChI=1S/2C10H12O5.Ca/c2*1-2-6(11)9-7(12)3-5(10(14)15)4-8(9)13;/h2*5,11H,2-4H2,1H3,(H,14,15);/q;;+2/p-2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: France Prohexadione-calcium 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prohexadione (considered variant prohexadione-calcium) 26Mar2010 2010 doi:10.2903/j.efsa.2010.1555
+Prohexadione-calcium 127277-53-6 single chemical entity Component is identical to the substance Prohexadione-calcium 127277-53-6 Calcium;1-(4-carboxy-2,6-dioxocyclohexylidene)propan-1-olate Not in list C20H22CaO10 CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].[Ca+2] InChI=1S/2C10H12O5.Ca/c2*1-2-6(11)9-7(12)3-5(10(14)15)4-8(9)13;/h2*5,11H,2-4H2,1H3,(H,14,15);/q;;+2/p-2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: France Prohexadione-calcium 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prohexadione (considered variant prohexadione-calcium) 26Mar2010 2010 doi:10.2903/j.efsa.2010.1555
+Prohexadione-calcium 127277-53-6 single chemical entity Component is identical to the substance Prohexadione-calcium 127277-53-6 Calcium;1-(4-carboxy-2,6-dioxocyclohexylidene)propan-1-olate Not in list C20H22CaO10 CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].[Ca+2] InChI=1S/2C10H12O5.Ca/c2*1-2-6(11)9-7(12)3-5(10(14)15)4-8(9)13;/h2*5,11H,2-4H2,1H3,(H,14,15);/q;;+2/p-2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: France Prohexadione-calcium 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prohexadione (considered variant prohexadione-calcium) 26Mar2010 2010 doi:10.2903/j.efsa.2010.1555
+Prohexadione-calcium 127277-53-6 single chemical entity Component is identical to the substance Prohexadione-calcium 127277-53-6 Calcium;1-(4-carboxy-2,6-dioxocyclohexylidene)propan-1-olate Not in list C20H22CaO10 CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].[Ca+2] InChI=1S/2C10H12O5.Ca/c2*1-2-6(11)9-7(12)3-5(10(14)15)4-8(9)13;/h2*5,11H,2-4H2,1H3,(H,14,15);/q;;+2/p-2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: France Prohexadione-calcium 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prohexadione (considered variant prohexadione-calcium) 26Mar2010 2010 doi:10.2903/j.efsa.2010.1555
+Prohexadione-calcium 127277-53-6 single chemical entity Component is identical to the substance Prohexadione-calcium 127277-53-6 Calcium;1-(4-carboxy-2,6-dioxocyclohexylidene)propan-1-olate Not in list C20H22CaO10 CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].[Ca+2] InChI=1S/2C10H12O5.Ca/c2*1-2-6(11)9-7(12)3-5(10(14)15)4-8(9)13;/h2*5,11H,2-4H2,1H3,(H,14,15);/q;;+2/p-2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: France Prohexadione-calcium 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prohexadione (considered variant prohexadione-calcium) 26Mar2010 2010 doi:10.2903/j.efsa.2010.1555
+Prohexadione-calcium 127277-53-6 single chemical entity Component is identical to the substance Prohexadione-calcium 127277-53-6 Calcium;1-(4-carboxy-2,6-dioxocyclohexylidene)propan-1-olate Not in list C20H22CaO10 CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].[Ca+2] InChI=1S/2C10H12O5.Ca/c2*1-2-6(11)9-7(12)3-5(10(14)15)4-8(9)13;/h2*5,11H,2-4H2,1H3,(H,14,15);/q;;+2/p-2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: France Prohexadione-calcium 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prohexadione (considered variant prohexadione-calcium) 26Mar2010 2010 doi:10.2903/j.efsa.2010.1555
+Prohexadione-calcium 127277-53-6 single chemical entity Component is identical to the substance Prohexadione-calcium 127277-53-6 Calcium;1-(4-carboxy-2,6-dioxocyclohexylidene)propan-1-olate Not in list C20H22CaO10 CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].[Ca+2] InChI=1S/2C10H12O5.Ca/c2*1-2-6(11)9-7(12)3-5(10(14)15)4-8(9)13;/h2*5,11H,2-4H2,1H3,(H,14,15);/q;;+2/p-2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: France Prohexadione-calcium 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prohexadione (considered variant prohexadione-calcium) 26Mar2010 2010 doi:10.2903/j.efsa.2010.1555
+Prohexadione-calcium 127277-53-6 single chemical entity Component is identical to the substance Prohexadione-calcium 127277-53-6 Calcium;1-(4-carboxy-2,6-dioxocyclohexylidene)propan-1-olate Not in list C20H22CaO10 CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].[Ca+2] InChI=1S/2C10H12O5.Ca/c2*1-2-6(11)9-7(12)3-5(10(14)15)4-8(9)13;/h2*5,11H,2-4H2,1H3,(H,14,15);/q;;+2/p-2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: France Prohexadione-calcium 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prohexadione (considered variant prohexadione-calcium) 26Mar2010 2010 doi:10.2903/j.efsa.2010.1555
+Prohexadione-calcium 127277-53-6 single chemical entity Component is identical to the substance Prohexadione-calcium 127277-53-6 Calcium;1-(4-carboxy-2,6-dioxocyclohexylidene)propan-1-olate Not in list C20H22CaO10 CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].[Ca+2] InChI=1S/2C10H12O5.Ca/c2*1-2-6(11)9-7(12)3-5(10(14)15)4-8(9)13;/h2*5,11H,2-4H2,1H3,(H,14,15);/q;;+2/p-2 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data without Negative RMS: France Prohexadione-calcium 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prohexadione (considered variant prohexadione-calcium) 26Mar2010 2010 doi:10.2903/j.efsa.2010.1555
+Prohexadione-calcium 127277-53-6 single chemical entity Component is identical to the substance Prohexadione-calcium 127277-53-6 Calcium;1-(4-carboxy-2,6-dioxocyclohexylidene)propan-1-olate Not in list C20H22CaO10 CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].[Ca+2] InChI=1S/2C10H12O5.Ca/c2*1-2-6(11)9-7(12)3-5(10(14)15)4-8(9)13;/h2*5,11H,2-4H2,1H3,(H,14,15);/q;;+2/p-2 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data with Negative RMS: France Prohexadione-calcium 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prohexadione (considered variant prohexadione-calcium) 26Mar2010 2010 doi:10.2903/j.efsa.2010.1555
+Prohexadione-calcium 127277-53-6 single chemical entity Component is identical to the substance Prohexadione-calcium 127277-53-6 Calcium;1-(4-carboxy-2,6-dioxocyclohexylidene)propan-1-olate Not in list C20H22CaO10 CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].[Ca+2] InChI=1S/2C10H12O5.Ca/c2*1-2-6(11)9-7(12)3-5(10(14)15)4-8(9)13;/h2*5,11H,2-4H2,1H3,(H,14,15);/q;;+2/p-2 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported no data with Negative RMS: France Prohexadione-calcium 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prohexadione (considered variant prohexadione-calcium) 26Mar2010 2010 doi:10.2903/j.efsa.2010.1555
+Prohexadione-calcium 127277-53-6 single chemical entity Component is identical to the substance Prohexadione-calcium 127277-53-6 Calcium;1-(4-carboxy-2,6-dioxocyclohexylidene)propan-1-olate Not in list C20H22CaO10 CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].[Ca+2] InChI=1S/2C10H12O5.Ca/c2*1-2-6(11)9-7(12)3-5(10(14)15)4-8(9)13;/h2*5,11H,2-4H2,1H3,(H,14,15);/q;;+2/p-2 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported no data without Negative RMS: France Prohexadione-calcium 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prohexadione (considered variant prohexadione-calcium) 26Mar2010 2010 doi:10.2903/j.efsa.2010.1555
+Prohexadione-calcium 127277-53-6 single chemical entity Component is identical to the substance Prohexadione-calcium 127277-53-6 Calcium;1-(4-carboxy-2,6-dioxocyclohexylidene)propan-1-olate Not in list C20H22CaO10 CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].[Ca+2] InChI=1S/2C10H12O5.Ca/c2*1-2-6(11)9-7(12)3-5(10(14)15)4-8(9)13;/h2*5,11H,2-4H2,1H3,(H,14,15);/q;;+2/p-2 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported no data without Negative RMS: France Prohexadione-calcium 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prohexadione (considered variant prohexadione-calcium) 26Mar2010 2010 doi:10.2903/j.efsa.2010.1555
+Prohexadione-calcium 127277-53-6 single chemical entity Component is identical to the substance Prohexadione-calcium 127277-53-6 Calcium;1-(4-carboxy-2,6-dioxocyclohexylidene)propan-1-olate Not in list C20H22CaO10 CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].[Ca+2] InChI=1S/2C10H12O5.Ca/c2*1-2-6(11)9-7(12)3-5(10(14)15)4-8(9)13;/h2*5,11H,2-4H2,1H3,(H,14,15);/q;;+2/p-2 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported no data without Negative RMS: France Prohexadione-calcium 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prohexadione (considered variant prohexadione-calcium) 26Mar2010 2010 doi:10.2903/j.efsa.2010.1555
+Prohexadione-calcium 127277-53-6 single chemical entity Component is identical to the substance Prohexadione-calcium 127277-53-6 Calcium;1-(4-carboxy-2,6-dioxocyclohexylidene)propan-1-olate Not in list C20H22CaO10 CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].[Ca+2] InChI=1S/2C10H12O5.Ca/c2*1-2-6(11)9-7(12)3-5(10(14)15)4-8(9)13;/h2*5,11H,2-4H2,1H3,(H,14,15);/q;;+2/p-2 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported no data without Negative RMS: France Prohexadione-calcium 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prohexadione (considered variant prohexadione-calcium) 26Mar2010 2010 doi:10.2903/j.efsa.2010.1555
+Prohexadione-calcium 127277-53-6 single chemical entity Component is identical to the substance Prohexadione-calcium 127277-53-6 Calcium;1-(4-carboxy-2,6-dioxocyclohexylidene)propan-1-olate Not in list C20H22CaO10 CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].[Ca+2] InChI=1S/2C10H12O5.Ca/c2*1-2-6(11)9-7(12)3-5(10(14)15)4-8(9)13;/h2*5,11H,2-4H2,1H3,(H,14,15);/q;;+2/p-2 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported no data with Negative RMS: France Prohexadione-calcium 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prohexadione (considered variant prohexadione-calcium) 26Mar2010 2010 doi:10.2903/j.efsa.2010.1555
+Prohexadione-calcium 127277-53-6 single chemical entity Component is identical to the substance Prohexadione-calcium 127277-53-6 Calcium;1-(4-carboxy-2,6-dioxocyclohexylidene)propan-1-olate Not in list C20H22CaO10 CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].[Ca+2] InChI=1S/2C10H12O5.Ca/c2*1-2-6(11)9-7(12)3-5(10(14)15)4-8(9)13;/h2*5,11H,2-4H2,1H3,(H,14,15);/q;;+2/p-2 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported no data with Negative RMS: France Prohexadione-calcium 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prohexadione (considered variant prohexadione-calcium) 26Mar2010 2010 doi:10.2903/j.efsa.2010.1555
+Prohexadione-calcium 127277-53-6 single chemical entity Component is identical to the substance Prohexadione-calcium 127277-53-6 Calcium;1-(4-carboxy-2,6-dioxocyclohexylidene)propan-1-olate Not in list C20H22CaO10 CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].[Ca+2] InChI=1S/2C10H12O5.Ca/c2*1-2-6(11)9-7(12)3-5(10(14)15)4-8(9)13;/h2*5,11H,2-4H2,1H3,(H,14,15);/q;;+2/p-2 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Crj:CD(SD) 10 Male/Female oral: gavage 24.0000000000 h no data not applicable Negative RMS: France Prohexadione-calcium 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prohexadione (considered variant prohexadione-calcium) 26Mar2010 2010 doi:10.2903/j.efsa.2010.1555
+Prohexadione-calcium 127277-53-6 single chemical entity Component is identical to the substance Prohexadione-calcium 127277-53-6 Calcium;1-(4-carboxy-2,6-dioxocyclohexylidene)propan-1-olate Not in list C20H22CaO10 CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].[Ca+2] InChI=1S/2C10H12O5.Ca/c2*1-2-6(11)9-7(12)3-5(10(14)15)4-8(9)13;/h2*5,11H,2-4H2,1H3,(H,14,15);/q;;+2/p-2 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Crj:CD(SD) 10 Male/Female oral: gavage 6.0000000000 h no data not applicable Negative RMS: France Prohexadione-calcium 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prohexadione (considered variant prohexadione-calcium) 26Mar2010 2010 doi:10.2903/j.efsa.2010.1555
+Prohexadione-calcium 127277-53-6 single chemical entity Component is identical to the substance Prohexadione-calcium 127277-53-6 Calcium;1-(4-carboxy-2,6-dioxocyclohexylidene)propan-1-olate Not in list C20H22CaO10 CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].[Ca+2] InChI=1S/2C10H12O5.Ca/c2*1-2-6(11)9-7(12)3-5(10(14)15)4-8(9)13;/h2*5,11H,2-4H2,1H3,(H,14,15);/q;;+2/p-2 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Crj:CD(SD) 10 Male/Female oral: gavage 48.0000000000 h no data not applicable Negative RMS: France Prohexadione-calcium 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prohexadione (considered variant prohexadione-calcium) 26Mar2010 2010 doi:10.2903/j.efsa.2010.1555
+Prohexadione-calcium 127277-53-6 single chemical entity Component is identical to the substance Prohexadione-calcium 127277-53-6 Calcium;1-(4-carboxy-2,6-dioxocyclohexylidene)propan-1-olate Not in list C20H22CaO10 CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].[Ca+2] InChI=1S/2C10H12O5.Ca/c2*1-2-6(11)9-7(12)3-5(10(14)15)4-8(9)13;/h2*5,11H,2-4H2,1H3,(H,14,15);/q;;+2/p-2 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 30 Male/Female oral: gavage 72.0000000000 h no data not applicable Negative no evidence RMS: France Prohexadione-calcium 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prohexadione (considered variant prohexadione-calcium) 26Mar2010 2010 doi:10.2903/j.efsa.2010.1555
+Prohexadione-calcium 127277-53-6 single chemical entity Component is identical to the substance Prohexadione-calcium 127277-53-6 Calcium;1-(4-carboxy-2,6-dioxocyclohexylidene)propan-1-olate Not in list C20H22CaO10 CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].[Ca+2] InChI=1S/2C10H12O5.Ca/c2*1-2-6(11)9-7(12)3-5(10(14)15)4-8(9)13;/h2*5,11H,2-4H2,1H3,(H,14,15);/q;;+2/p-2 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 30 Male/Female oral: gavage 48.0000000000 h no data not applicable Negative no evidence RMS: France Prohexadione-calcium 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prohexadione (considered variant prohexadione-calcium) 26Mar2010 2010 doi:10.2903/j.efsa.2010.1555
+Prohexadione-calcium 127277-53-6 single chemical entity Component is identical to the substance Prohexadione-calcium 127277-53-6 Calcium;1-(4-carboxy-2,6-dioxocyclohexylidene)propan-1-olate Not in list C20H22CaO10 CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].[Ca+2] InChI=1S/2C10H12O5.Ca/c2*1-2-6(11)9-7(12)3-5(10(14)15)4-8(9)13;/h2*5,11H,2-4H2,1H3,(H,14,15);/q;;+2/p-2 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 30 Male/Female oral: gavage 24.0000000000 h no data not applicable Negative no evidence RMS: France Prohexadione-calcium 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prohexadione (considered variant prohexadione-calcium) 26Mar2010 2010 doi:10.2903/j.efsa.2010.1555
+Proquinazid 189278-12-4 single chemical entity Component is identical to the substance Proquinazid 189278-12-4 6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one Proquinazid C14H17IN2O2 Ic1ccc2N=C(OCCC)N(CCC)C(=O)c2c1 InChI=1S/C14H17IN2O2/c1-3-7-17-13(18)11-9-10(15)5-6-12(11)16-14(17)19-8-4-2/h5-6,9H,3-4,7-8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The United Kingdom Proquinazid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid 29Oct2009 2009 doi:10.2903/j.efsa.2009.1350
+Proquinazid 189278-12-4 single chemical entity Component is identical to the substance Proquinazid 189278-12-4 6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one Proquinazid C14H17IN2O2 Ic1ccc2N=C(OCCC)N(CCC)C(=O)c2c1 InChI=1S/C14H17IN2O2/c1-3-7-17-13(18)11-9-10(15)5-6-12(11)16-14(17)19-8-4-2/h5-6,9H,3-4,7-8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes without Negative RMS: The United Kingdom Proquinazid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid 29Oct2009 2009 doi:10.2903/j.efsa.2009.1350
+Proquinazid 189278-12-4 single chemical entity Component is identical to the substance Proquinazid 189278-12-4 6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one Proquinazid C14H17IN2O2 Ic1ccc2N=C(OCCC)N(CCC)C(=O)c2c1 InChI=1S/C14H17IN2O2/c1-3-7-17-13(18)11-9-10(15)5-6-12(11)16-14(17)19-8-4-2/h5-6,9H,3-4,7-8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes with Negative RMS: The United Kingdom Proquinazid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid 29Oct2009 2009 doi:10.2903/j.efsa.2009.1350
+Proquinazid 189278-12-4 single chemical entity Component is identical to the substance Proquinazid 189278-12-4 6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one Proquinazid C14H17IN2O2 Ic1ccc2N=C(OCCC)N(CCC)C(=O)c2c1 InChI=1S/C14H17IN2O2/c1-3-7-17-13(18)11-9-10(15)5-6-12(11)16-14(17)19-8-4-2/h5-6,9H,3-4,7-8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The United Kingdom Proquinazid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid 29Oct2009 2009 doi:10.2903/j.efsa.2009.1350
+Proquinazid 189278-12-4 single chemical entity Component is identical to the substance Proquinazid 189278-12-4 6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one Proquinazid C14H17IN2O2 Ic1ccc2N=C(OCCC)N(CCC)C(=O)c2c1 InChI=1S/C14H17IN2O2/c1-3-7-17-13(18)11-9-10(15)5-6-12(11)16-14(17)19-8-4-2/h5-6,9H,3-4,7-8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The United Kingdom Proquinazid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid 29Oct2009 2009 doi:10.2903/j.efsa.2009.1350
+Proquinazid 189278-12-4 single chemical entity Component is identical to the substance Proquinazid 189278-12-4 6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one Proquinazid C14H17IN2O2 Ic1ccc2N=C(OCCC)N(CCC)C(=O)c2c1 InChI=1S/C14H17IN2O2/c1-3-7-17-13(18)11-9-10(15)5-6-12(11)16-14(17)19-8-4-2/h5-6,9H,3-4,7-8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The United Kingdom Proquinazid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid 29Oct2009 2009 doi:10.2903/j.efsa.2009.1350
+Proquinazid 189278-12-4 single chemical entity Component is identical to the substance Proquinazid 189278-12-4 6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one Proquinazid C14H17IN2O2 Ic1ccc2N=C(OCCC)N(CCC)C(=O)c2c1 InChI=1S/C14H17IN2O2/c1-3-7-17-13(18)11-9-10(15)5-6-12(11)16-14(17)19-8-4-2/h5-6,9H,3-4,7-8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes without Negative RMS: The United Kingdom Proquinazid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid 29Oct2009 2009 doi:10.2903/j.efsa.2009.1350
+Proquinazid 189278-12-4 single chemical entity Component is identical to the substance Proquinazid 189278-12-4 6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one Proquinazid C14H17IN2O2 Ic1ccc2N=C(OCCC)N(CCC)C(=O)c2c1 InChI=1S/C14H17IN2O2/c1-3-7-17-13(18)11-9-10(15)5-6-12(11)16-14(17)19-8-4-2/h5-6,9H,3-4,7-8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes with Negative RMS: The United Kingdom Proquinazid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid 29Oct2009 2009 doi:10.2903/j.efsa.2009.1350
+Proquinazid 189278-12-4 single chemical entity Component is identical to the substance Proquinazid 189278-12-4 6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one Proquinazid C14H17IN2O2 Ic1ccc2N=C(OCCC)N(CCC)C(=O)c2c1 InChI=1S/C14H17IN2O2/c1-3-7-17-13(18)11-9-10(15)5-6-12(11)16-14(17)19-8-4-2/h5-6,9H,3-4,7-8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The United Kingdom Proquinazid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid 29Oct2009 2009 doi:10.2903/j.efsa.2009.1350
+Proquinazid 189278-12-4 single chemical entity Component is identical to the substance Proquinazid 189278-12-4 6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one Proquinazid C14H17IN2O2 Ic1ccc2N=C(OCCC)N(CCC)C(=O)c2c1 InChI=1S/C14H17IN2O2/c1-3-7-17-13(18)11-9-10(15)5-6-12(11)16-14(17)19-8-4-2/h5-6,9H,3-4,7-8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The United Kingdom Proquinazid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid 29Oct2009 2009 doi:10.2903/j.efsa.2009.1350
+Proquinazid 189278-12-4 single chemical entity Component is identical to the substance Proquinazid 189278-12-4 6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one Proquinazid C14H17IN2O2 Ic1ccc2N=C(OCCC)N(CCC)C(=O)c2c1 InChI=1S/C14H17IN2O2/c1-3-7-17-13(18)11-9-10(15)5-6-12(11)16-14(17)19-8-4-2/h5-6,9H,3-4,7-8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes without Negative RMS: The United Kingdom Proquinazid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid 29Oct2009 2009 doi:10.2903/j.efsa.2009.1350
+Proquinazid 189278-12-4 single chemical entity Component is identical to the substance Proquinazid 189278-12-4 6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one Proquinazid C14H17IN2O2 Ic1ccc2N=C(OCCC)N(CCC)C(=O)c2c1 InChI=1S/C14H17IN2O2/c1-3-7-17-13(18)11-9-10(15)5-6-12(11)16-14(17)19-8-4-2/h5-6,9H,3-4,7-8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The United Kingdom Proquinazid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid 29Oct2009 2009 doi:10.2903/j.efsa.2009.1350
+Proquinazid 189278-12-4 single chemical entity Component is identical to the substance Proquinazid 189278-12-4 6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one Proquinazid C14H17IN2O2 Ic1ccc2N=C(OCCC)N(CCC)C(=O)c2c1 InChI=1S/C14H17IN2O2/c1-3-7-17-13(18)11-9-10(15)5-6-12(11)16-14(17)19-8-4-2/h5-6,9H,3-4,7-8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The United Kingdom Proquinazid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid 29Oct2009 2009 doi:10.2903/j.efsa.2009.1350
+Proquinazid 189278-12-4 single chemical entity Component is identical to the substance Proquinazid 189278-12-4 6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one Proquinazid C14H17IN2O2 Ic1ccc2N=C(OCCC)N(CCC)C(=O)c2c1 InChI=1S/C14H17IN2O2/c1-3-7-17-13(18)11-9-10(15)5-6-12(11)16-14(17)19-8-4-2/h5-6,9H,3-4,7-8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The United Kingdom Proquinazid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid 29Oct2009 2009 doi:10.2903/j.efsa.2009.1350
+Proquinazid 189278-12-4 single chemical entity Component is identical to the substance Proquinazid 189278-12-4 6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one Proquinazid C14H17IN2O2 Ic1ccc2N=C(OCCC)N(CCC)C(=O)c2c1 InChI=1S/C14H17IN2O2/c1-3-7-17-13(18)11-9-10(15)5-6-12(11)16-14(17)19-8-4-2/h5-6,9H,3-4,7-8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The United Kingdom Proquinazid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid 29Oct2009 2009 doi:10.2903/j.efsa.2009.1350
+Proquinazid 189278-12-4 single chemical entity Component is identical to the substance Proquinazid 189278-12-4 6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one Proquinazid C14H17IN2O2 Ic1ccc2N=C(OCCC)N(CCC)C(=O)c2c1 InChI=1S/C14H17IN2O2/c1-3-7-17-13(18)11-9-10(15)5-6-12(11)16-14(17)19-8-4-2/h5-6,9H,3-4,7-8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The United Kingdom Proquinazid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid 29Oct2009 2009 doi:10.2903/j.efsa.2009.1350
+Proquinazid 189278-12-4 single chemical entity Component is identical to the substance Proquinazid 189278-12-4 6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one Proquinazid C14H17IN2O2 Ic1ccc2N=C(OCCC)N(CCC)C(=O)c2c1 InChI=1S/C14H17IN2O2/c1-3-7-17-13(18)11-9-10(15)5-6-12(11)16-14(17)19-8-4-2/h5-6,9H,3-4,7-8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes without Negative RMS: The United Kingdom Proquinazid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid 29Oct2009 2009 doi:10.2903/j.efsa.2009.1350
+Proquinazid 189278-12-4 single chemical entity Component is identical to the substance Proquinazid 189278-12-4 6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one Proquinazid C14H17IN2O2 Ic1ccc2N=C(OCCC)N(CCC)C(=O)c2c1 InChI=1S/C14H17IN2O2/c1-3-7-17-13(18)11-9-10(15)5-6-12(11)16-14(17)19-8-4-2/h5-6,9H,3-4,7-8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes with Negative RMS: The United Kingdom Proquinazid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid 29Oct2009 2009 doi:10.2903/j.efsa.2009.1350
+Proquinazid 189278-12-4 single chemical entity Component is identical to the substance Proquinazid 189278-12-4 6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one Proquinazid C14H17IN2O2 Ic1ccc2N=C(OCCC)N(CCC)C(=O)c2c1 InChI=1S/C14H17IN2O2/c1-3-7-17-13(18)11-9-10(15)5-6-12(11)16-14(17)19-8-4-2/h5-6,9H,3-4,7-8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The United Kingdom Proquinazid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid 29Oct2009 2009 doi:10.2903/j.efsa.2009.1350
+Proquinazid 189278-12-4 single chemical entity Component is identical to the substance Proquinazid 189278-12-4 6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one Proquinazid C14H17IN2O2 Ic1ccc2N=C(OCCC)N(CCC)C(=O)c2c1 InChI=1S/C14H17IN2O2/c1-3-7-17-13(18)11-9-10(15)5-6-12(11)16-14(17)19-8-4-2/h5-6,9H,3-4,7-8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes with Negative RMS: The United Kingdom Proquinazid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid 29Oct2009 2009 doi:10.2903/j.efsa.2009.1350
+Proquinazid 189278-12-4 single chemical entity Component is identical to the substance Proquinazid 189278-12-4 6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one Proquinazid C14H17IN2O2 Ic1ccc2N=C(OCCC)N(CCC)C(=O)c2c1 InChI=1S/C14H17IN2O2/c1-3-7-17-13(18)11-9-10(15)5-6-12(11)16-14(17)19-8-4-2/h5-6,9H,3-4,7-8H2,1-2H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes with Inconclusive RMS: The United Kingdom Proquinazid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid 29Oct2009 2009 doi:10.2903/j.efsa.2009.1350
+Proquinazid 189278-12-4 single chemical entity Component is identical to the substance Proquinazid 189278-12-4 6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one Proquinazid C14H17IN2O2 Ic1ccc2N=C(OCCC)N(CCC)C(=O)c2c1 InChI=1S/C14H17IN2O2/c1-3-7-17-13(18)11-9-10(15)5-6-12(11)16-14(17)19-8-4-2/h5-6,9H,3-4,7-8H2,1-2H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes without Inconclusive RMS: The United Kingdom Proquinazid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid 29Oct2009 2009 doi:10.2903/j.efsa.2009.1350
+Proquinazid 189278-12-4 single chemical entity Component is identical to the substance Proquinazid 189278-12-4 6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one Proquinazid C14H17IN2O2 Ic1ccc2N=C(OCCC)N(CCC)C(=O)c2c1 InChI=1S/C14H17IN2O2/c1-3-7-17-13(18)11-9-10(15)5-6-12(11)16-14(17)19-8-4-2/h5-6,9H,3-4,7-8H2,1-2H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: The United Kingdom Proquinazid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid 29Oct2009 2009 doi:10.2903/j.efsa.2009.1350
+Proquinazid 189278-12-4 single chemical entity Component is identical to the substance Proquinazid 189278-12-4 6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one Proquinazid C14H17IN2O2 Ic1ccc2N=C(OCCC)N(CCC)C(=O)c2c1 InChI=1S/C14H17IN2O2/c1-3-7-17-13(18)11-9-10(15)5-6-12(11)16-14(17)19-8-4-2/h5-6,9H,3-4,7-8H2,1-2H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: The United Kingdom Proquinazid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid 29Oct2009 2009 doi:10.2903/j.efsa.2009.1350
+Proquinazid 189278-12-4 single chemical entity Component is identical to the substance Proquinazid 189278-12-4 6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one Proquinazid C14H17IN2O2 Ic1ccc2N=C(OCCC)N(CCC)C(=O)c2c1 InChI=1S/C14H17IN2O2/c1-3-7-17-13(18)11-9-10(15)5-6-12(11)16-14(17)19-8-4-2/h5-6,9H,3-4,7-8H2,1-2H3 organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes without Negative RMS: The United Kingdom Proquinazid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid 29Oct2009 2009 doi:10.2903/j.efsa.2009.1350
+Proquinazid 189278-12-4 single chemical entity Component is identical to the substance Proquinazid 189278-12-4 6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one Proquinazid C14H17IN2O2 Ic1ccc2N=C(OCCC)N(CCC)C(=O)c2c1 InChI=1S/C14H17IN2O2/c1-3-7-17-13(18)11-9-10(15)5-6-12(11)16-14(17)19-8-4-2/h5-6,9H,3-4,7-8H2,1-2H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 48.0000000000 h yes not applicable Negative indirect evidence-systemic toxicity$indirect-toxicokinetic investigations RMS: The United Kingdom Proquinazid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid 29Oct2009 2009 doi:10.2903/j.efsa.2009.1350
+Proquinazid 189278-12-4 single chemical entity Component is identical to the substance Proquinazid 189278-12-4 6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one Proquinazid C14H17IN2O2 Ic1ccc2N=C(OCCC)N(CCC)C(=O)c2c1 InChI=1S/C14H17IN2O2/c1-3-7-17-13(18)11-9-10(15)5-6-12(11)16-14(17)19-8-4-2/h5-6,9H,3-4,7-8H2,1-2H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes not applicable Negative indirect evidence-systemic toxicity$indirect-toxicokinetic investigations RMS: The United Kingdom Proquinazid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid 29Oct2009 2009 doi:10.2903/j.efsa.2009.1350
+Proquinazid 189278-12-4 single chemical entity Component is identical to the substance Proquinazid 189278-12-4 6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one Proquinazid C14H17IN2O2 Ic1ccc2N=C(OCCC)N(CCC)C(=O)c2c1 InChI=1S/C14H17IN2O2/c1-3-7-17-13(18)11-9-10(15)5-6-12(11)16-14(17)19-8-4-2/h5-6,9H,3-4,7-8H2,1-2H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 48.0000000000 h yes not applicable Negative indirect evidence-systemic toxicity$indirect-toxicokinetic investigations RMS: The United Kingdom Proquinazid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid 29Oct2009 2009 doi:10.2903/j.efsa.2009.1350
+Proquinazid 189278-12-4 single chemical entity Component is identical to the substance Proquinazid 189278-12-4 6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one Proquinazid C14H17IN2O2 Ic1ccc2N=C(OCCC)N(CCC)C(=O)c2c1 InChI=1S/C14H17IN2O2/c1-3-7-17-13(18)11-9-10(15)5-6-12(11)16-14(17)19-8-4-2/h5-6,9H,3-4,7-8H2,1-2H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes not applicable Negative indirect evidence-systemic toxicity$indirect-toxicokinetic investigations RMS: The United Kingdom Proquinazid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid 29Oct2009 2009 doi:10.2903/j.efsa.2009.1350
+Proquinazid 189278-12-4 single chemical entity Component is identical to the substance Proquinazid 189278-12-4 6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one Proquinazid C14H17IN2O2 Ic1ccc2N=C(OCCC)N(CCC)C(=O)c2c1 InChI=1S/C14H17IN2O2/c1-3-7-17-13(18)11-9-10(15)5-6-12(11)16-14(17)19-8-4-2/h5-6,9H,3-4,7-8H2,1-2H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 72.0000000000 h yes not applicable Negative indirect evidence-systemic toxicity$indirect-toxicokinetic investigations RMS: The United Kingdom Proquinazid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid 29Oct2009 2009 doi:10.2903/j.efsa.2009.1350
+Proquinazid 189278-12-4 single chemical entity Component is a metabolite of the substance 2-Propoxy-3-propylquinazolin-4(3H)-one 2-propoxy-3-propylquinazolin-4(3H)-one Not in list C14H18N2O2 CCCOC2=Nc1ccccc1C(=O)N2CCC InChI=1S/C14H18N2O2/c1-3-9-16-13(17)11-7-5-6-8-12(11)15-14(16)18-10-4-2/h5-8H,3-4,9-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes with Negative RMS: The United Kingdom Proquinazid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid 29Oct2009 2009 doi:10.2903/j.efsa.2009.1350
+Proquinazid 189278-12-4 single chemical entity Component is a metabolite of the substance 2-Propoxy-3-propylquinazolin-4(3H)-one 2-propoxy-3-propylquinazolin-4(3H)-one Not in list C14H18N2O2 CCCOC2=Nc1ccccc1C(=O)N2CCC InChI=1S/C14H18N2O2/c1-3-9-16-13(17)11-7-5-6-8-12(11)15-14(16)18-10-4-2/h5-8H,3-4,9-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The United Kingdom Proquinazid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid 29Oct2009 2009 doi:10.2903/j.efsa.2009.1350
+Proquinazid 189278-12-4 single chemical entity Component is a metabolite of the substance 2-Propoxy-3-propylquinazolin-4(3H)-one 2-propoxy-3-propylquinazolin-4(3H)-one Not in list C14H18N2O2 CCCOC2=Nc1ccccc1C(=O)N2CCC InChI=1S/C14H18N2O2/c1-3-9-16-13(17)11-7-5-6-8-12(11)15-14(16)18-10-4-2/h5-8H,3-4,9-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The United Kingdom Proquinazid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid 29Oct2009 2009 doi:10.2903/j.efsa.2009.1350
+Proquinazid 189278-12-4 single chemical entity Component is a metabolite of the substance 2-Propoxy-3-propylquinazolin-4(3H)-one 2-propoxy-3-propylquinazolin-4(3H)-one Not in list C14H18N2O2 CCCOC2=Nc1ccccc1C(=O)N2CCC InChI=1S/C14H18N2O2/c1-3-9-16-13(17)11-7-5-6-8-12(11)15-14(16)18-10-4-2/h5-8H,3-4,9-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The United Kingdom Proquinazid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid 29Oct2009 2009 doi:10.2903/j.efsa.2009.1350
+Proquinazid 189278-12-4 single chemical entity Component is a metabolite of the substance 2-Propoxy-3-propylquinazolin-4(3H)-one 2-propoxy-3-propylquinazolin-4(3H)-one Not in list C14H18N2O2 CCCOC2=Nc1ccccc1C(=O)N2CCC InChI=1S/C14H18N2O2/c1-3-9-16-13(17)11-7-5-6-8-12(11)15-14(16)18-10-4-2/h5-8H,3-4,9-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The United Kingdom Proquinazid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid 29Oct2009 2009 doi:10.2903/j.efsa.2009.1350
+Proquinazid 189278-12-4 single chemical entity Component is a metabolite of the substance 2-Propoxy-3-propylquinazolin-4(3H)-one 2-propoxy-3-propylquinazolin-4(3H)-one Not in list C14H18N2O2 CCCOC2=Nc1ccccc1C(=O)N2CCC InChI=1S/C14H18N2O2/c1-3-9-16-13(17)11-7-5-6-8-12(11)15-14(16)18-10-4-2/h5-8H,3-4,9-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The United Kingdom Proquinazid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid 29Oct2009 2009 doi:10.2903/j.efsa.2009.1350
+Proquinazid 189278-12-4 single chemical entity Component is a metabolite of the substance 2-Propoxy-3-propylquinazolin-4(3H)-one 2-propoxy-3-propylquinazolin-4(3H)-one Not in list C14H18N2O2 CCCOC2=Nc1ccccc1C(=O)N2CCC InChI=1S/C14H18N2O2/c1-3-9-16-13(17)11-7-5-6-8-12(11)15-14(16)18-10-4-2/h5-8H,3-4,9-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes without Negative RMS: The United Kingdom Proquinazid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid 29Oct2009 2009 doi:10.2903/j.efsa.2009.1350
+Proquinazid 189278-12-4 single chemical entity Component is a metabolite of the substance 2-Propoxy-3-propylquinazolin-4(3H)-one 2-propoxy-3-propylquinazolin-4(3H)-one Not in list C14H18N2O2 CCCOC2=Nc1ccccc1C(=O)N2CCC InChI=1S/C14H18N2O2/c1-3-9-16-13(17)11-7-5-6-8-12(11)15-14(16)18-10-4-2/h5-8H,3-4,9-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes with Negative RMS: The United Kingdom Proquinazid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid 29Oct2009 2009 doi:10.2903/j.efsa.2009.1350
+Proquinazid 189278-12-4 single chemical entity Component is a metabolite of the substance 2-Propoxy-3-propylquinazolin-4(3H)-one 2-propoxy-3-propylquinazolin-4(3H)-one Not in list C14H18N2O2 CCCOC2=Nc1ccccc1C(=O)N2CCC InChI=1S/C14H18N2O2/c1-3-9-16-13(17)11-7-5-6-8-12(11)15-14(16)18-10-4-2/h5-8H,3-4,9-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes without Negative RMS: The United Kingdom Proquinazid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid 29Oct2009 2009 doi:10.2903/j.efsa.2009.1350
+Proquinazid 189278-12-4 single chemical entity Component is a metabolite of the substance 2-Propoxy-3-propylquinazolin-4(3H)-one 2-propoxy-3-propylquinazolin-4(3H)-one Not in list C14H18N2O2 CCCOC2=Nc1ccccc1C(=O)N2CCC InChI=1S/C14H18N2O2/c1-3-9-16-13(17)11-7-5-6-8-12(11)15-14(16)18-10-4-2/h5-8H,3-4,9-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The United Kingdom Proquinazid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid 29Oct2009 2009 doi:10.2903/j.efsa.2009.1350
+Proquinazid 189278-12-4 single chemical entity Component is a metabolite of the substance 2-Propoxy-3-propylquinazolin-4(3H)-one 2-propoxy-3-propylquinazolin-4(3H)-one Not in list C14H18N2O2 CCCOC2=Nc1ccccc1C(=O)N2CCC InChI=1S/C14H18N2O2/c1-3-9-16-13(17)11-7-5-6-8-12(11)15-14(16)18-10-4-2/h5-8H,3-4,9-10H2,1-2H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 48.0000000000 h yes not applicable Negative direct evidence-cytotoxicity$indirect evidence-systemic toxicity$indirect-toxicokinetic investigations RMS: The United Kingdom Proquinazid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid 29Oct2009 2009 doi:10.2903/j.efsa.2009.1350
+Proquinazid 189278-12-4 single chemical entity Component is a metabolite of the substance 2-Propoxy-3-propylquinazolin-4(3H)-one 2-propoxy-3-propylquinazolin-4(3H)-one Not in list C14H18N2O2 CCCOC2=Nc1ccccc1C(=O)N2CCC InChI=1S/C14H18N2O2/c1-3-9-16-13(17)11-7-5-6-8-12(11)15-14(16)18-10-4-2/h5-8H,3-4,9-10H2,1-2H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes not applicable Negative direct evidence-cytotoxicity$indirect evidence-systemic toxicity$indirect-toxicokinetic investigations RMS: The United Kingdom Proquinazid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid 29Oct2009 2009 doi:10.2903/j.efsa.2009.1350
+Pyrimethanil 414-220-3 53112-28-0 single chemical entity Component is identical to the substance Pyrimethanil 414-220-3 53112-28-0 4,6-dimethyl-N-phenylpyrimidin-2-amine Pyrimethanil C12H13N3 CC1=NC(NC2=CC=CC=C2)=NC(C)=C1 InChI=1S/C12H13N3/c1-9-8-10(2)14-12(13-9)15-11-6-4-3-5-7-11/h3-8H,1-2H3,(H,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Austria Pyrimethanil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil 21Feb2006 2006 doi:10.2903/j.efsa.2006.61r
+Pyrimethanil 414-220-3 53112-28-0 single chemical entity Component is identical to the substance Pyrimethanil 414-220-3 53112-28-0 4,6-dimethyl-N-phenylpyrimidin-2-amine Pyrimethanil C12H13N3 CC1=NC(NC2=CC=CC=C2)=NC(C)=C1 InChI=1S/C12H13N3/c1-9-8-10(2)14-12(13-9)15-11-6-4-3-5-7-11/h3-8H,1-2H3,(H,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Austria Pyrimethanil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil 21Feb2006 2006 doi:10.2903/j.efsa.2006.61r
+Pyrimethanil 414-220-3 53112-28-0 single chemical entity Component is identical to the substance Pyrimethanil 414-220-3 53112-28-0 4,6-dimethyl-N-phenylpyrimidin-2-amine Pyrimethanil C12H13N3 CC1=NC(NC2=CC=CC=C2)=NC(C)=C1 InChI=1S/C12H13N3/c1-9-8-10(2)14-12(13-9)15-11-6-4-3-5-7-11/h3-8H,1-2H3,(H,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Austria Pyrimethanil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil 21Feb2006 2006 doi:10.2903/j.efsa.2006.61r
+Pyrimethanil 414-220-3 53112-28-0 single chemical entity Component is identical to the substance Pyrimethanil 414-220-3 53112-28-0 4,6-dimethyl-N-phenylpyrimidin-2-amine Pyrimethanil C12H13N3 CC1=NC(NC2=CC=CC=C2)=NC(C)=C1 InChI=1S/C12H13N3/c1-9-8-10(2)14-12(13-9)15-11-6-4-3-5-7-11/h3-8H,1-2H3,(H,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Austria Pyrimethanil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil 21Feb2006 2006 doi:10.2903/j.efsa.2006.61r
+Pyrimethanil 414-220-3 53112-28-0 single chemical entity Component is identical to the substance Pyrimethanil 414-220-3 53112-28-0 4,6-dimethyl-N-phenylpyrimidin-2-amine Pyrimethanil C12H13N3 CC1=NC(NC2=CC=CC=C2)=NC(C)=C1 InChI=1S/C12H13N3/c1-9-8-10(2)14-12(13-9)15-11-6-4-3-5-7-11/h3-8H,1-2H3,(H,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Austria Pyrimethanil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil 21Feb2006 2006 doi:10.2903/j.efsa.2006.61r
+Pyrimethanil 414-220-3 53112-28-0 single chemical entity Component is identical to the substance Pyrimethanil 414-220-3 53112-28-0 4,6-dimethyl-N-phenylpyrimidin-2-amine Pyrimethanil C12H13N3 CC1=NC(NC2=CC=CC=C2)=NC(C)=C1 InChI=1S/C12H13N3/c1-9-8-10(2)14-12(13-9)15-11-6-4-3-5-7-11/h3-8H,1-2H3,(H,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Austria Pyrimethanil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil 21Feb2006 2006 doi:10.2903/j.efsa.2006.61r
+Pyrimethanil 414-220-3 53112-28-0 single chemical entity Component is identical to the substance Pyrimethanil 414-220-3 53112-28-0 4,6-dimethyl-N-phenylpyrimidin-2-amine Pyrimethanil C12H13N3 CC1=NC(NC2=CC=CC=C2)=NC(C)=C1 InChI=1S/C12H13N3/c1-9-8-10(2)14-12(13-9)15-11-6-4-3-5-7-11/h3-8H,1-2H3,(H,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Austria Pyrimethanil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil 21Feb2006 2006 doi:10.2903/j.efsa.2006.61r
+Pyrimethanil 414-220-3 53112-28-0 single chemical entity Component is identical to the substance Pyrimethanil 414-220-3 53112-28-0 4,6-dimethyl-N-phenylpyrimidin-2-amine Pyrimethanil C12H13N3 CC1=NC(NC2=CC=CC=C2)=NC(C)=C1 InChI=1S/C12H13N3/c1-9-8-10(2)14-12(13-9)15-11-6-4-3-5-7-11/h3-8H,1-2H3,(H,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Austria Pyrimethanil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil 21Feb2006 2006 doi:10.2903/j.efsa.2006.61r
+Pyrimethanil 414-220-3 53112-28-0 single chemical entity Component is identical to the substance Pyrimethanil 414-220-3 53112-28-0 4,6-dimethyl-N-phenylpyrimidin-2-amine Pyrimethanil C12H13N3 CC1=NC(NC2=CC=CC=C2)=NC(C)=C1 InChI=1S/C12H13N3/c1-9-8-10(2)14-12(13-9)15-11-6-4-3-5-7-11/h3-8H,1-2H3,(H,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Austria Pyrimethanil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil 21Feb2006 2006 doi:10.2903/j.efsa.2006.61r
+Pyrimethanil 414-220-3 53112-28-0 single chemical entity Component is identical to the substance Pyrimethanil 414-220-3 53112-28-0 4,6-dimethyl-N-phenylpyrimidin-2-amine Pyrimethanil C12H13N3 CC1=NC(NC2=CC=CC=C2)=NC(C)=C1 InChI=1S/C12H13N3/c1-9-8-10(2)14-12(13-9)15-11-6-4-3-5-7-11/h3-8H,1-2H3,(H,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Austria Pyrimethanil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil 21Feb2006 2006 doi:10.2903/j.efsa.2006.61r
+Pyrimethanil 414-220-3 53112-28-0 single chemical entity Component is identical to the substance Pyrimethanil 414-220-3 53112-28-0 4,6-dimethyl-N-phenylpyrimidin-2-amine Pyrimethanil C12H13N3 CC1=NC(NC2=CC=CC=C2)=NC(C)=C1 InChI=1S/C12H13N3/c1-9-8-10(2)14-12(13-9)15-11-6-4-3-5-7-11/h3-8H,1-2H3,(H,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) CM881 Not reported yes, concurrent vehicle with Negative RMS: Austria Pyrimethanil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil 21Feb2006 2006 doi:10.2903/j.efsa.2006.61r
+Pyrimethanil 414-220-3 53112-28-0 single chemical entity Component is identical to the substance Pyrimethanil 414-220-3 53112-28-0 4,6-dimethyl-N-phenylpyrimidin-2-amine Pyrimethanil C12H13N3 CC1=NC(NC2=CC=CC=C2)=NC(C)=C1 InChI=1S/C12H13N3/c1-9-8-10(2)14-12(13-9)15-11-6-4-3-5-7-11/h3-8H,1-2H3,(H,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) CM881 Not reported yes, concurrent vehicle without Negative RMS: Austria Pyrimethanil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil 21Feb2006 2006 doi:10.2903/j.efsa.2006.61r
+Pyrimethanil 414-220-3 53112-28-0 single chemical entity Component is identical to the substance Pyrimethanil 414-220-3 53112-28-0 4,6-dimethyl-N-phenylpyrimidin-2-amine Pyrimethanil C12H13N3 CC1=NC(NC2=CC=CC=C2)=NC(C)=C1 InChI=1S/C12H13N3/c1-9-8-10(2)14-12(13-9)15-11-6-4-3-5-7-11/h3-8H,1-2H3,(H,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) CM891 Not reported yes, concurrent vehicle with Negative RMS: Austria Pyrimethanil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil 21Feb2006 2006 doi:10.2903/j.efsa.2006.61r
+Pyrimethanil 414-220-3 53112-28-0 single chemical entity Component is identical to the substance Pyrimethanil 414-220-3 53112-28-0 4,6-dimethyl-N-phenylpyrimidin-2-amine Pyrimethanil C12H13N3 CC1=NC(NC2=CC=CC=C2)=NC(C)=C1 InChI=1S/C12H13N3/c1-9-8-10(2)14-12(13-9)15-11-6-4-3-5-7-11/h3-8H,1-2H3,(H,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) CM891 Not reported yes, concurrent vehicle without Negative RMS: Austria Pyrimethanil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil 21Feb2006 2006 doi:10.2903/j.efsa.2006.61r
+Pyrimethanil 414-220-3 53112-28-0 single chemical entity Component is identical to the substance Pyrimethanil 414-220-3 53112-28-0 4,6-dimethyl-N-phenylpyrimidin-2-amine Pyrimethanil C12H13N3 CC1=NC(NC2=CC=CC=C2)=NC(C)=C1 InChI=1S/C12H13N3/c1-9-8-10(2)14-12(13-9)15-11-6-4-3-5-7-11/h3-8H,1-2H3,(H,13,14,15) organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes, concurrent vehicle without Negative RMS: Austria Pyrimethanil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil 21Feb2006 2006 doi:10.2903/j.efsa.2006.61r
+Pyrimethanil 414-220-3 53112-28-0 single chemical entity Component is identical to the substance Pyrimethanil 414-220-3 53112-28-0 4,6-dimethyl-N-phenylpyrimidin-2-amine Pyrimethanil C12H13N3 CC1=NC(NC2=CC=CC=C2)=NC(C)=C1 InChI=1S/C12H13N3/c1-9-8-10(2)14-12(13-9)15-11-6-4-3-5-7-11/h3-8H,1-2H3,(H,13,14,15) organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes, concurrent vehicle with Negative RMS: Austria Pyrimethanil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil 21Feb2006 2006 doi:10.2903/j.efsa.2006.61r
+Pyrimethanil 414-220-3 53112-28-0 single chemical entity Component is identical to the substance Pyrimethanil 414-220-3 53112-28-0 4,6-dimethyl-N-phenylpyrimidin-2-amine Pyrimethanil C12H13N3 CC1=NC(NC2=CC=CC=C2)=NC(C)=C1 InChI=1S/C12H13N3/c1-9-8-10(2)14-12(13-9)15-11-6-4-3-5-7-11/h3-8H,1-2H3,(H,13,14,15) organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes, concurrent vehicle with Negative RMS: Austria Pyrimethanil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil 21Feb2006 2006 doi:10.2903/j.efsa.2006.61r
+Pyrimethanil 414-220-3 53112-28-0 single chemical entity Component is identical to the substance Pyrimethanil 414-220-3 53112-28-0 4,6-dimethyl-N-phenylpyrimidin-2-amine Pyrimethanil C12H13N3 CC1=NC(NC2=CC=CC=C2)=NC(C)=C1 InChI=1S/C12H13N3/c1-9-8-10(2)14-12(13-9)15-11-6-4-3-5-7-11/h3-8H,1-2H3,(H,13,14,15) organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes, concurrent vehicle without Negative RMS: Austria Pyrimethanil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil 21Feb2006 2006 doi:10.2903/j.efsa.2006.61r
+Pyrimethanil 414-220-3 53112-28-0 single chemical entity Component is identical to the substance Pyrimethanil 414-220-3 53112-28-0 4,6-dimethyl-N-phenylpyrimidin-2-amine Pyrimethanil C12H13N3 CC1=NC(NC2=CC=CC=C2)=NC(C)=C1 InChI=1S/C12H13N3/c1-9-8-10(2)14-12(13-9)15-11-6-4-3-5-7-11/h3-8H,1-2H3,(H,13,14,15) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Austria Pyrimethanil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil 21Feb2006 2006 doi:10.2903/j.efsa.2006.61r
+Pyrimethanil 414-220-3 53112-28-0 single chemical entity Component is identical to the substance Pyrimethanil 414-220-3 53112-28-0 4,6-dimethyl-N-phenylpyrimidin-2-amine Pyrimethanil C12H13N3 CC1=NC(NC2=CC=CC=C2)=NC(C)=C1 InChI=1S/C12H13N3/c1-9-8-10(2)14-12(13-9)15-11-6-4-3-5-7-11/h3-8H,1-2H3,(H,13,14,15) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Austria Pyrimethanil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil 21Feb2006 2006 doi:10.2903/j.efsa.2006.61r
+Pyrimethanil 414-220-3 53112-28-0 single chemical entity Component is identical to the substance Pyrimethanil 414-220-3 53112-28-0 4,6-dimethyl-N-phenylpyrimidin-2-amine Pyrimethanil C12H13N3 CC1=NC(NC2=CC=CC=C2)=NC(C)=C1 InChI=1S/C12H13N3/c1-9-8-10(2)14-12(13-9)15-11-6-4-3-5-7-11/h3-8H,1-2H3,(H,13,14,15) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Austria Pyrimethanil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil 21Feb2006 2006 doi:10.2903/j.efsa.2006.61r
+Pyrimethanil 414-220-3 53112-28-0 single chemical entity Component is identical to the substance Pyrimethanil 414-220-3 53112-28-0 4,6-dimethyl-N-phenylpyrimidin-2-amine Pyrimethanil C12H13N3 CC1=NC(NC2=CC=CC=C2)=NC(C)=C1 InChI=1S/C12H13N3/c1-9-8-10(2)14-12(13-9)15-11-6-4-3-5-7-11/h3-8H,1-2H3,(H,13,14,15) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Austria Pyrimethanil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil 21Feb2006 2006 doi:10.2903/j.efsa.2006.61r
+Pyrimethanil 414-220-3 53112-28-0 single chemical entity Component is identical to the substance Pyrimethanil 414-220-3 53112-28-0 4,6-dimethyl-N-phenylpyrimidin-2-amine Pyrimethanil C12H13N3 CC1=NC(NC2=CC=CC=C2)=NC(C)=C1 InChI=1S/C12H13N3/c1-9-8-10(2)14-12(13-9)15-11-6-4-3-5-7-11/h3-8H,1-2H3,(H,13,14,15) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 30 Male/Female oral: gavage 72.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Austria Pyrimethanil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil 21Feb2006 2006 doi:10.2903/j.efsa.2006.61r
+Pyrimethanil 414-220-3 53112-28-0 single chemical entity Component is identical to the substance Pyrimethanil 414-220-3 53112-28-0 4,6-dimethyl-N-phenylpyrimidin-2-amine Pyrimethanil C12H13N3 CC1=NC(NC2=CC=CC=C2)=NC(C)=C1 InChI=1S/C12H13N3/c1-9-8-10(2)14-12(13-9)15-11-6-4-3-5-7-11/h3-8H,1-2H3,(H,13,14,15) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 30 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Austria Pyrimethanil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil 21Feb2006 2006 doi:10.2903/j.efsa.2006.61r
+Pyrimethanil 414-220-3 53112-28-0 single chemical entity Component is identical to the substance Pyrimethanil 414-220-3 53112-28-0 4,6-dimethyl-N-phenylpyrimidin-2-amine Pyrimethanil C12H13N3 CC1=NC(NC2=CC=CC=C2)=NC(C)=C1 InChI=1S/C12H13N3/c1-9-8-10(2)14-12(13-9)15-11-6-4-3-5-7-11/h3-8H,1-2H3,(H,13,14,15) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 30 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Austria Pyrimethanil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil 21Feb2006 2006 doi:10.2903/j.efsa.2006.61r
+Pyrimethanil 414-220-3 53112-28-0 single chemical entity Component is identical to the substance Pyrimethanil 414-220-3 53112-28-0 4,6-dimethyl-N-phenylpyrimidin-2-amine Pyrimethanil C12H13N3 CC1=NC(NC2=CC=CC=C2)=NC(C)=C1 InChI=1S/C12H13N3/c1-9-8-10(2)14-12(13-9)15-11-6-4-3-5-7-11/h3-8H,1-2H3,(H,13,14,15) organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Sprague-Dawley 6 Male oral: gavage 2.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Austria Pyrimethanil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil 21Feb2006 2006 doi:10.2903/j.efsa.2006.61r
+Pyrimethanil 414-220-3 53112-28-0 single chemical entity Component is identical to the substance Pyrimethanil 414-220-3 53112-28-0 4,6-dimethyl-N-phenylpyrimidin-2-amine Pyrimethanil C12H13N3 CC1=NC(NC2=CC=CC=C2)=NC(C)=C1 InChI=1S/C12H13N3/c1-9-8-10(2)14-12(13-9)15-11-6-4-3-5-7-11/h3-8H,1-2H3,(H,13,14,15) organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Sprague-Dawley 6 Male oral: gavage 14.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Austria Pyrimethanil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil 21Feb2006 2006 doi:10.2903/j.efsa.2006.61r
+Pyrimethanil 414-220-3 53112-28-0 single chemical entity Component is a metabolite of the substance 2-amino-4,6-dimethylpyrimidine 4,6-dimethylpyrimidin-2-amine Pyrimethanil metabolite (AEF132593) C6H9N3 Cc1cc(C)nc(N)n1 InChI=1/C6H9N3/c1-4-3-5(2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Austria Pyrimethanil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil 21Feb2006 2006 doi:10.2903/j.efsa.2006.61r
+Pyrimethanil 414-220-3 53112-28-0 single chemical entity Component is a metabolite of the substance 2-amino-4,6-dimethylpyrimidine 4,6-dimethylpyrimidin-2-amine Pyrimethanil metabolite (AEF132593) C6H9N3 Cc1cc(C)nc(N)n1 InChI=1/C6H9N3/c1-4-3-5(2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Austria Pyrimethanil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil 21Feb2006 2006 doi:10.2903/j.efsa.2006.61r
+Pyrimethanil 414-220-3 53112-28-0 single chemical entity Component is a metabolite of the substance 2-amino-4,6-dimethylpyrimidine 4,6-dimethylpyrimidin-2-amine Pyrimethanil metabolite (AEF132593) C6H9N3 Cc1cc(C)nc(N)n1 InChI=1/C6H9N3/c1-4-3-5(2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) CM891 Not reported yes, concurrent vehicle without Negative RMS: Austria Pyrimethanil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil 21Feb2006 2006 doi:10.2903/j.efsa.2006.61r
+Pyrimethanil 414-220-3 53112-28-0 single chemical entity Component is a metabolite of the substance 2-amino-4,6-dimethylpyrimidine 4,6-dimethylpyrimidin-2-amine Pyrimethanil metabolite (AEF132593) C6H9N3 Cc1cc(C)nc(N)n1 InChI=1/C6H9N3/c1-4-3-5(2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Austria Pyrimethanil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil 21Feb2006 2006 doi:10.2903/j.efsa.2006.61r
+Pyrimethanil 414-220-3 53112-28-0 single chemical entity Component is a metabolite of the substance 2-amino-4,6-dimethylpyrimidine 4,6-dimethylpyrimidin-2-amine Pyrimethanil metabolite (AEF132593) C6H9N3 Cc1cc(C)nc(N)n1 InChI=1/C6H9N3/c1-4-3-5(2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Austria Pyrimethanil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil 21Feb2006 2006 doi:10.2903/j.efsa.2006.61r
+Pyrimethanil 414-220-3 53112-28-0 single chemical entity Component is a metabolite of the substance 2-amino-4,6-dimethylpyrimidine 4,6-dimethylpyrimidin-2-amine Pyrimethanil metabolite (AEF132593) C6H9N3 Cc1cc(C)nc(N)n1 InChI=1/C6H9N3/c1-4-3-5(2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Austria Pyrimethanil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil 21Feb2006 2006 doi:10.2903/j.efsa.2006.61r
+Pyrimethanil 414-220-3 53112-28-0 single chemical entity Component is a metabolite of the substance 2-amino-4,6-dimethylpyrimidine 4,6-dimethylpyrimidin-2-amine Pyrimethanil metabolite (AEF132593) C6H9N3 Cc1cc(C)nc(N)n1 InChI=1/C6H9N3/c1-4-3-5(2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Austria Pyrimethanil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil 21Feb2006 2006 doi:10.2903/j.efsa.2006.61r
+Pyrimethanil 414-220-3 53112-28-0 single chemical entity Component is a metabolite of the substance 2-amino-4,6-dimethylpyrimidine 4,6-dimethylpyrimidin-2-amine Pyrimethanil metabolite (AEF132593) C6H9N3 Cc1cc(C)nc(N)n1 InChI=1/C6H9N3/c1-4-3-5(2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Austria Pyrimethanil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil 21Feb2006 2006 doi:10.2903/j.efsa.2006.61r
+Pyrimethanil 414-220-3 53112-28-0 single chemical entity Component is a metabolite of the substance 2-amino-4,6-dimethylpyrimidine 4,6-dimethylpyrimidin-2-amine Pyrimethanil metabolite (AEF132593) C6H9N3 Cc1cc(C)nc(N)n1 InChI=1/C6H9N3/c1-4-3-5(2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) CM891 Not reported yes, concurrent vehicle with Negative RMS: Austria Pyrimethanil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil 21Feb2006 2006 doi:10.2903/j.efsa.2006.61r
+Pyrimethanil 414-220-3 53112-28-0 single chemical entity Component is a metabolite of the substance 2-amino-4,6-dimethylpyrimidine 4,6-dimethylpyrimidin-2-amine Pyrimethanil metabolite (AEF132593) C6H9N3 Cc1cc(C)nc(N)n1 InChI=1/C6H9N3/c1-4-3-5(2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Austria Pyrimethanil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil 21Feb2006 2006 doi:10.2903/j.efsa.2006.61r
+Oxadiazon 243-215-7 19666-30-9 single chemical entity Component is identical to the substance Oxadiazon 243-215-7 19666-30-9 5-Tert-butyl-3-(2,4-dichloro-5-propan-2-yloxyphenyl)-1,3,4-oxadiazol-2-one Oxadiazon C15H18Cl2N2O3 CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Italy Oxadiazon 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxadiazon 19Feb2010 2010 doi:10.2903/j.efsa.2010.1389
+Oxadiazon 243-215-7 19666-30-9 single chemical entity Component is identical to the substance Oxadiazon 243-215-7 19666-30-9 5-Tert-butyl-3-(2,4-dichloro-5-propan-2-yloxyphenyl)-1,3,4-oxadiazol-2-one Oxadiazon C15H18Cl2N2O3 CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Italy Oxadiazon 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxadiazon 19Feb2010 2010 doi:10.2903/j.efsa.2010.1389
+Oxadiazon 243-215-7 19666-30-9 single chemical entity Component is identical to the substance Oxadiazon 243-215-7 19666-30-9 5-Tert-butyl-3-(2,4-dichloro-5-propan-2-yloxyphenyl)-1,3,4-oxadiazol-2-one Oxadiazon C15H18Cl2N2O3 CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Italy Oxadiazon 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxadiazon 19Feb2010 2010 doi:10.2903/j.efsa.2010.1389
+Oxadiazon 243-215-7 19666-30-9 single chemical entity Component is identical to the substance Oxadiazon 243-215-7 19666-30-9 5-Tert-butyl-3-(2,4-dichloro-5-propan-2-yloxyphenyl)-1,3,4-oxadiazol-2-one Oxadiazon C15H18Cl2N2O3 CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Italy Oxadiazon 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxadiazon 19Feb2010 2010 doi:10.2903/j.efsa.2010.1389
+Oxadiazon 243-215-7 19666-30-9 single chemical entity Component is identical to the substance Oxadiazon 243-215-7 19666-30-9 5-Tert-butyl-3-(2,4-dichloro-5-propan-2-yloxyphenyl)-1,3,4-oxadiazol-2-one Oxadiazon C15H18Cl2N2O3 CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Italy Oxadiazon 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxadiazon 19Feb2010 2010 doi:10.2903/j.efsa.2010.1389
+Oxadiazon 243-215-7 19666-30-9 single chemical entity Component is identical to the substance Oxadiazon 243-215-7 19666-30-9 5-Tert-butyl-3-(2,4-dichloro-5-propan-2-yloxyphenyl)-1,3,4-oxadiazol-2-one Oxadiazon C15H18Cl2N2O3 CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Italy Oxadiazon 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxadiazon 19Feb2010 2010 doi:10.2903/j.efsa.2010.1389
+Oxadiazon 243-215-7 19666-30-9 single chemical entity Component is identical to the substance Oxadiazon 243-215-7 19666-30-9 5-Tert-butyl-3-(2,4-dichloro-5-propan-2-yloxyphenyl)-1,3,4-oxadiazol-2-one Oxadiazon C15H18Cl2N2O3 CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Italy Oxadiazon 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxadiazon 19Feb2010 2010 doi:10.2903/j.efsa.2010.1389
+Oxadiazon 243-215-7 19666-30-9 single chemical entity Component is identical to the substance Oxadiazon 243-215-7 19666-30-9 5-Tert-butyl-3-(2,4-dichloro-5-propan-2-yloxyphenyl)-1,3,4-oxadiazol-2-one Oxadiazon C15H18Cl2N2O3 CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Italy Oxadiazon 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxadiazon 19Feb2010 2010 doi:10.2903/j.efsa.2010.1389
+Oxadiazon 243-215-7 19666-30-9 single chemical entity Component is identical to the substance Oxadiazon 243-215-7 19666-30-9 5-Tert-butyl-3-(2,4-dichloro-5-propan-2-yloxyphenyl)-1,3,4-oxadiazol-2-one Oxadiazon C15H18Cl2N2O3 CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Italy Oxadiazon 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxadiazon 19Feb2010 2010 doi:10.2903/j.efsa.2010.1389
+Oxadiazon 243-215-7 19666-30-9 single chemical entity Component is identical to the substance Oxadiazon 243-215-7 19666-30-9 5-Tert-butyl-3-(2,4-dichloro-5-propan-2-yloxyphenyl)-1,3,4-oxadiazol-2-one Oxadiazon C15H18Cl2N2O3 CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Italy Oxadiazon 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxadiazon 19Feb2010 2010 doi:10.2903/j.efsa.2010.1389
+Oxadiazon 243-215-7 19666-30-9 single chemical entity Component is identical to the substance Oxadiazon 243-215-7 19666-30-9 5-Tert-butyl-3-(2,4-dichloro-5-propan-2-yloxyphenyl)-1,3,4-oxadiazol-2-one Oxadiazon C15H18Cl2N2O3 CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle without Negative RMS: Italy Oxadiazon 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxadiazon 19Feb2010 2010 doi:10.2903/j.efsa.2010.1389
+Oxadiazon 243-215-7 19666-30-9 single chemical entity Component is identical to the substance Oxadiazon 243-215-7 19666-30-9 5-Tert-butyl-3-(2,4-dichloro-5-propan-2-yloxyphenyl)-1,3,4-oxadiazol-2-one Oxadiazon C15H18Cl2N2O3 CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle with Negative RMS: Italy Oxadiazon 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxadiazon 19Feb2010 2010 doi:10.2903/j.efsa.2010.1389
+Oxadiazon 243-215-7 19666-30-9 single chemical entity Component is identical to the substance Oxadiazon 243-215-7 19666-30-9 5-Tert-butyl-3-(2,4-dichloro-5-propan-2-yloxyphenyl)-1,3,4-oxadiazol-2-one Oxadiazon C15H18Cl2N2O3 CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle with Negative RMS: Italy Oxadiazon 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxadiazon 19Feb2010 2010 doi:10.2903/j.efsa.2010.1389
+Oxadiazon 243-215-7 19666-30-9 single chemical entity Component is identical to the substance Oxadiazon 243-215-7 19666-30-9 5-Tert-butyl-3-(2,4-dichloro-5-propan-2-yloxyphenyl)-1,3,4-oxadiazol-2-one Oxadiazon C15H18Cl2N2O3 CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Italy Oxadiazon 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxadiazon 19Feb2010 2010 doi:10.2903/j.efsa.2010.1389
+Oxadiazon 243-215-7 19666-30-9 single chemical entity Component is identical to the substance Oxadiazon 243-215-7 19666-30-9 5-Tert-butyl-3-(2,4-dichloro-5-propan-2-yloxyphenyl)-1,3,4-oxadiazol-2-one Oxadiazon C15H18Cl2N2O3 CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Italy Oxadiazon 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxadiazon 19Feb2010 2010 doi:10.2903/j.efsa.2010.1389
+Oxadiazon 243-215-7 19666-30-9 single chemical entity Component is identical to the substance Oxadiazon 243-215-7 19666-30-9 5-Tert-butyl-3-(2,4-dichloro-5-propan-2-yloxyphenyl)-1,3,4-oxadiazol-2-one Oxadiazon C15H18Cl2N2O3 CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Italy Oxadiazon 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxadiazon 19Feb2010 2010 doi:10.2903/j.efsa.2010.1389
+Oxadiazon 243-215-7 19666-30-9 single chemical entity Component is identical to the substance Oxadiazon 243-215-7 19666-30-9 5-Tert-butyl-3-(2,4-dichloro-5-propan-2-yloxyphenyl)-1,3,4-oxadiazol-2-one Oxadiazon C15H18Cl2N2O3 CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Positive RMS: Italy Oxadiazon 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxadiazon 19Feb2010 2010 doi:10.2903/j.efsa.2010.1389
+Oxadiazon 243-215-7 19666-30-9 single chemical entity Component is identical to the substance Oxadiazon 243-215-7 19666-30-9 5-Tert-butyl-3-(2,4-dichloro-5-propan-2-yloxyphenyl)-1,3,4-oxadiazol-2-one Oxadiazon C15H18Cl2N2O3 CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Positive RMS: Italy Oxadiazon 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxadiazon 19Feb2010 2010 doi:10.2903/j.efsa.2010.1389
+Oxadiazon 243-215-7 19666-30-9 single chemical entity Component is identical to the substance Oxadiazon 243-215-7 19666-30-9 5-Tert-butyl-3-(2,4-dichloro-5-propan-2-yloxyphenyl)-1,3,4-oxadiazol-2-one Oxadiazon C15H18Cl2N2O3 CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Italy Oxadiazon 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxadiazon 19Feb2010 2010 doi:10.2903/j.efsa.2010.1389
+Oxadiazon 243-215-7 19666-30-9 single chemical entity Component is identical to the substance Oxadiazon 243-215-7 19666-30-9 5-Tert-butyl-3-(2,4-dichloro-5-propan-2-yloxyphenyl)-1,3,4-oxadiazol-2-one Oxadiazon C15H18Cl2N2O3 CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Italy Oxadiazon 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxadiazon 19Feb2010 2010 doi:10.2903/j.efsa.2010.1389
+Oxadiazon 243-215-7 19666-30-9 single chemical entity Component is identical to the substance Oxadiazon 243-215-7 19666-30-9 5-Tert-butyl-3-(2,4-dichloro-5-propan-2-yloxyphenyl)-1,3,4-oxadiazol-2-one Oxadiazon C15H18Cl2N2O3 CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Italy Oxadiazon 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxadiazon 19Feb2010 2010 doi:10.2903/j.efsa.2010.1389
+Oxadiazon 243-215-7 19666-30-9 single chemical entity Component is identical to the substance Oxadiazon 243-215-7 19666-30-9 5-Tert-butyl-3-(2,4-dichloro-5-propan-2-yloxyphenyl)-1,3,4-oxadiazol-2-one Oxadiazon C15H18Cl2N2O3 CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle without Negative RMS: Italy Oxadiazon 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxadiazon 19Feb2010 2010 doi:10.2903/j.efsa.2010.1389
+Oxadiazon 243-215-7 19666-30-9 single chemical entity Component is identical to the substance Oxadiazon 243-215-7 19666-30-9 5-Tert-butyl-3-(2,4-dichloro-5-propan-2-yloxyphenyl)-1,3,4-oxadiazol-2-one Oxadiazon C15H18Cl2N2O3 CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Italy Oxadiazon 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxadiazon 19Feb2010 2010 doi:10.2903/j.efsa.2010.1389
+Oxadiazon 243-215-7 19666-30-9 single chemical entity Component is identical to the substance Oxadiazon 243-215-7 19666-30-9 5-Tert-butyl-3-(2,4-dichloro-5-propan-2-yloxyphenyl)-1,3,4-oxadiazol-2-one Oxadiazon C15H18Cl2N2O3 CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Italy Oxadiazon 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxadiazon 19Feb2010 2010 doi:10.2903/j.efsa.2010.1389
+Oxadiazon 243-215-7 19666-30-9 single chemical entity Component is identical to the substance Oxadiazon 243-215-7 19666-30-9 5-Tert-butyl-3-(2,4-dichloro-5-propan-2-yloxyphenyl)-1,3,4-oxadiazol-2-one Oxadiazon C15H18Cl2N2O3 CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Italy Oxadiazon 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxadiazon 19Feb2010 2010 doi:10.2903/j.efsa.2010.1389
+Oxadiazon 243-215-7 19666-30-9 single chemical entity Component is identical to the substance Oxadiazon 243-215-7 19666-30-9 5-Tert-butyl-3-(2,4-dichloro-5-propan-2-yloxyphenyl)-1,3,4-oxadiazol-2-one Oxadiazon C15H18Cl2N2O3 CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Italy Oxadiazon 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxadiazon 19Feb2010 2010 doi:10.2903/j.efsa.2010.1389
+Oxadiazon 243-215-7 19666-30-9 single chemical entity Component is identical to the substance Oxadiazon 243-215-7 19666-30-9 5-Tert-butyl-3-(2,4-dichloro-5-propan-2-yloxyphenyl)-1,3,4-oxadiazol-2-one Oxadiazon C15H18Cl2N2O3 CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Italy Oxadiazon 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxadiazon 19Feb2010 2010 doi:10.2903/j.efsa.2010.1389
+Oxadiazon 243-215-7 19666-30-9 single chemical entity Component is identical to the substance Oxadiazon 243-215-7 19666-30-9 5-Tert-butyl-3-(2,4-dichloro-5-propan-2-yloxyphenyl)-1,3,4-oxadiazol-2-one Oxadiazon C15H18Cl2N2O3 CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Italy Oxadiazon 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxadiazon 19Feb2010 2010 doi:10.2903/j.efsa.2010.1389
+Oxadiazon 243-215-7 19666-30-9 single chemical entity Component is identical to the substance Oxadiazon 243-215-7 19666-30-9 5-Tert-butyl-3-(2,4-dichloro-5-propan-2-yloxyphenyl)-1,3,4-oxadiazol-2-one Oxadiazon C15H18Cl2N2O3 CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 6 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Italy Oxadiazon 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxadiazon 19Feb2010 2010 doi:10.2903/j.efsa.2010.1389
+Oxadiazon 243-215-7 19666-30-9 single chemical entity Component is identical to the substance Oxadiazon 243-215-7 19666-30-9 5-Tert-butyl-3-(2,4-dichloro-5-propan-2-yloxyphenyl)-1,3,4-oxadiazol-2-one Oxadiazon C15H18Cl2N2O3 CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 8 Male/Female oral: unspecified 48.0000000000 h yes not applicable Negative no evidence RMS: Italy Oxadiazon 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxadiazon 19Feb2010 2010 doi:10.2903/j.efsa.2010.1389
+Oxadiazon 243-215-7 19666-30-9 single chemical entity Component is identical to the substance Oxadiazon 243-215-7 19666-30-9 5-Tert-butyl-3-(2,4-dichloro-5-propan-2-yloxyphenyl)-1,3,4-oxadiazol-2-one Oxadiazon C15H18Cl2N2O3 CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable Rat (as animal) Sprague-Dawley 2 Male oral: gavage 24.0000000000 h no data not applicable Negative RMS: Italy Oxadiazon 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxadiazon 19Feb2010 2010 doi:10.2903/j.efsa.2010.1389
+Oxadiazon 243-215-7 19666-30-9 single chemical entity Component is identical to the substance Oxadiazon 243-215-7 19666-30-9 5-Tert-butyl-3-(2,4-dichloro-5-propan-2-yloxyphenyl)-1,3,4-oxadiazol-2-one Oxadiazon C15H18Cl2N2O3 CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) CD-1 4 Male oral: gavage 24.0000000000 h no data not applicable Negative RMS: Italy Oxadiazon 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxadiazon 19Feb2010 2010 doi:10.2903/j.efsa.2010.1389
+Methiocarb 217-991-2 2032-65-7 single chemical entity Component is identical to the substance Methiocarb 217-991-2 2032-65-7 3,5-dimethyl-4-(methylsulfanyl)phenyl methylcarbamate Methiocarb C11H15NO2S CNC(=O)Oc1cc(C)c(SC)c(C)c1 InChI=1/C11H15NO2S/c1-7-5-9(14-11(13)12-3)6-8(2)10(7)15-4/h5-6H,1-4H3,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The United Kingdom Methiocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance methiocarb 30Jul2012 2012 doi:10.2903/j.efsa.2012.2758
+Methiocarb 217-991-2 2032-65-7 single chemical entity Component is identical to the substance Methiocarb 217-991-2 2032-65-7 3,5-dimethyl-4-(methylsulfanyl)phenyl methylcarbamate Methiocarb C11H15NO2S CNC(=O)Oc1cc(C)c(SC)c(C)c1 InChI=1/C11H15NO2S/c1-7-5-9(14-11(13)12-3)6-8(2)10(7)15-4/h5-6H,1-4H3,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The United Kingdom Methiocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance methiocarb 30Jul2012 2012 doi:10.2903/j.efsa.2012.2758
+Methiocarb 217-991-2 2032-65-7 single chemical entity Component is identical to the substance Methiocarb 217-991-2 2032-65-7 3,5-dimethyl-4-(methylsulfanyl)phenyl methylcarbamate Methiocarb C11H15NO2S CNC(=O)Oc1cc(C)c(SC)c(C)c1 InChI=1/C11H15NO2S/c1-7-5-9(14-11(13)12-3)6-8(2)10(7)15-4/h5-6H,1-4H3,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The United Kingdom Methiocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance methiocarb 30Jul2012 2012 doi:10.2903/j.efsa.2012.2758
+Methiocarb 217-991-2 2032-65-7 single chemical entity Component is identical to the substance Methiocarb 217-991-2 2032-65-7 3,5-dimethyl-4-(methylsulfanyl)phenyl methylcarbamate Methiocarb C11H15NO2S CNC(=O)Oc1cc(C)c(SC)c(C)c1 InChI=1/C11H15NO2S/c1-7-5-9(14-11(13)12-3)6-8(2)10(7)15-4/h5-6H,1-4H3,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The United Kingdom Methiocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance methiocarb 30Jul2012 2012 doi:10.2903/j.efsa.2012.2758
+Methiocarb 217-991-2 2032-65-7 single chemical entity Component is identical to the substance Methiocarb 217-991-2 2032-65-7 3,5-dimethyl-4-(methylsulfanyl)phenyl methylcarbamate Methiocarb C11H15NO2S CNC(=O)Oc1cc(C)c(SC)c(C)c1 InChI=1/C11H15NO2S/c1-7-5-9(14-11(13)12-3)6-8(2)10(7)15-4/h5-6H,1-4H3,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The United Kingdom Methiocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance methiocarb 30Jul2012 2012 doi:10.2903/j.efsa.2012.2758
+Methiocarb 217-991-2 2032-65-7 single chemical entity Component is identical to the substance Methiocarb 217-991-2 2032-65-7 3,5-dimethyl-4-(methylsulfanyl)phenyl methylcarbamate Methiocarb C11H15NO2S CNC(=O)Oc1cc(C)c(SC)c(C)c1 InChI=1/C11H15NO2S/c1-7-5-9(14-11(13)12-3)6-8(2)10(7)15-4/h5-6H,1-4H3,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The United Kingdom Methiocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance methiocarb 30Jul2012 2012 doi:10.2903/j.efsa.2012.2758
+Methiocarb 217-991-2 2032-65-7 single chemical entity Component is identical to the substance Methiocarb 217-991-2 2032-65-7 3,5-dimethyl-4-(methylsulfanyl)phenyl methylcarbamate Methiocarb C11H15NO2S CNC(=O)Oc1cc(C)c(SC)c(C)c1 InChI=1/C11H15NO2S/c1-7-5-9(14-11(13)12-3)6-8(2)10(7)15-4/h5-6H,1-4H3,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The United Kingdom Methiocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance methiocarb 30Jul2012 2012 doi:10.2903/j.efsa.2012.2758
+Methiocarb 217-991-2 2032-65-7 single chemical entity Component is identical to the substance Methiocarb 217-991-2 2032-65-7 3,5-dimethyl-4-(methylsulfanyl)phenyl methylcarbamate Methiocarb C11H15NO2S CNC(=O)Oc1cc(C)c(SC)c(C)c1 InChI=1/C11H15NO2S/c1-7-5-9(14-11(13)12-3)6-8(2)10(7)15-4/h5-6H,1-4H3,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The United Kingdom Methiocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance methiocarb 30Jul2012 2012 doi:10.2903/j.efsa.2012.2758
+Methiocarb 217-991-2 2032-65-7 single chemical entity Component is identical to the substance Methiocarb 217-991-2 2032-65-7 3,5-dimethyl-4-(methylsulfanyl)phenyl methylcarbamate Methiocarb C11H15NO2S CNC(=O)Oc1cc(C)c(SC)c(C)c1 InChI=1/C11H15NO2S/c1-7-5-9(14-11(13)12-3)6-8(2)10(7)15-4/h5-6H,1-4H3,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Methiocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance methiocarb 30Jul2012 2012 doi:10.2903/j.efsa.2012.2758
+Methiocarb 217-991-2 2032-65-7 single chemical entity Component is identical to the substance Methiocarb 217-991-2 2032-65-7 3,5-dimethyl-4-(methylsulfanyl)phenyl methylcarbamate Methiocarb C11H15NO2S CNC(=O)Oc1cc(C)c(SC)c(C)c1 InChI=1/C11H15NO2S/c1-7-5-9(14-11(13)12-3)6-8(2)10(7)15-4/h5-6H,1-4H3,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Methiocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance methiocarb 30Jul2012 2012 doi:10.2903/j.efsa.2012.2758
+Methiocarb 217-991-2 2032-65-7 single chemical entity Component is identical to the substance Methiocarb 217-991-2 2032-65-7 3,5-dimethyl-4-(methylsulfanyl)phenyl methylcarbamate Methiocarb C11H15NO2S CNC(=O)Oc1cc(C)c(SC)c(C)c1 InChI=1/C11H15NO2S/c1-7-5-9(14-11(13)12-3)6-8(2)10(7)15-4/h5-6H,1-4H3,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Methiocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance methiocarb 30Jul2012 2012 doi:10.2903/j.efsa.2012.2758
+Methiocarb 217-991-2 2032-65-7 single chemical entity Component is identical to the substance Methiocarb 217-991-2 2032-65-7 3,5-dimethyl-4-(methylsulfanyl)phenyl methylcarbamate Methiocarb C11H15NO2S CNC(=O)Oc1cc(C)c(SC)c(C)c1 InChI=1/C11H15NO2S/c1-7-5-9(14-11(13)12-3)6-8(2)10(7)15-4/h5-6H,1-4H3,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Methiocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance methiocarb 30Jul2012 2012 doi:10.2903/j.efsa.2012.2758
+Methiocarb 217-991-2 2032-65-7 single chemical entity Component is identical to the substance Methiocarb 217-991-2 2032-65-7 3,5-dimethyl-4-(methylsulfanyl)phenyl methylcarbamate Methiocarb C11H15NO2S CNC(=O)Oc1cc(C)c(SC)c(C)c1 InChI=1/C11H15NO2S/c1-7-5-9(14-11(13)12-3)6-8(2)10(7)15-4/h5-6H,1-4H3,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Methiocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance methiocarb 30Jul2012 2012 doi:10.2903/j.efsa.2012.2758
+Methiocarb 217-991-2 2032-65-7 single chemical entity Component is identical to the substance Methiocarb 217-991-2 2032-65-7 3,5-dimethyl-4-(methylsulfanyl)phenyl methylcarbamate Methiocarb C11H15NO2S CNC(=O)Oc1cc(C)c(SC)c(C)c1 InChI=1/C11H15NO2S/c1-7-5-9(14-11(13)12-3)6-8(2)10(7)15-4/h5-6H,1-4H3,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Methiocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance methiocarb 30Jul2012 2012 doi:10.2903/j.efsa.2012.2758
+Methiocarb 217-991-2 2032-65-7 single chemical entity Component is identical to the substance Methiocarb 217-991-2 2032-65-7 3,5-dimethyl-4-(methylsulfanyl)phenyl methylcarbamate Methiocarb C11H15NO2S CNC(=O)Oc1cc(C)c(SC)c(C)c1 InChI=1/C11H15NO2S/c1-7-5-9(14-11(13)12-3)6-8(2)10(7)15-4/h5-6H,1-4H3,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Methiocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance methiocarb 30Jul2012 2012 doi:10.2903/j.efsa.2012.2758
+Methiocarb 217-991-2 2032-65-7 single chemical entity Component is identical to the substance Methiocarb 217-991-2 2032-65-7 3,5-dimethyl-4-(methylsulfanyl)phenyl methylcarbamate Methiocarb C11H15NO2S CNC(=O)Oc1cc(C)c(SC)c(C)c1 InChI=1/C11H15NO2S/c1-7-5-9(14-11(13)12-3)6-8(2)10(7)15-4/h5-6H,1-4H3,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Methiocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance methiocarb 30Jul2012 2012 doi:10.2903/j.efsa.2012.2758
+Methiocarb 217-991-2 2032-65-7 single chemical entity Component is identical to the substance Methiocarb 217-991-2 2032-65-7 3,5-dimethyl-4-(methylsulfanyl)phenyl methylcarbamate Methiocarb C11H15NO2S CNC(=O)Oc1cc(C)c(SC)c(C)c1 InChI=1/C11H15NO2S/c1-7-5-9(14-11(13)12-3)6-8(2)10(7)15-4/h5-6H,1-4H3,(H,12,13) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: The United Kingdom Methiocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance methiocarb 30Jul2012 2012 doi:10.2903/j.efsa.2012.2758
+Methiocarb 217-991-2 2032-65-7 single chemical entity Component is identical to the substance Methiocarb 217-991-2 2032-65-7 3,5-dimethyl-4-(methylsulfanyl)phenyl methylcarbamate Methiocarb C11H15NO2S CNC(=O)Oc1cc(C)c(SC)c(C)c1 InChI=1/C11H15NO2S/c1-7-5-9(14-11(13)12-3)6-8(2)10(7)15-4/h5-6H,1-4H3,(H,12,13) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: The United Kingdom Methiocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance methiocarb 30Jul2012 2012 doi:10.2903/j.efsa.2012.2758
+Methiocarb 217-991-2 2032-65-7 single chemical entity Component is identical to the substance Methiocarb 217-991-2 2032-65-7 3,5-dimethyl-4-(methylsulfanyl)phenyl methylcarbamate Methiocarb C11H15NO2S CNC(=O)Oc1cc(C)c(SC)c(C)c1 InChI=1/C11H15NO2S/c1-7-5-9(14-11(13)12-3)6-8(2)10(7)15-4/h5-6H,1-4H3,(H,12,13) organic compound Other Other gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) DNA-polymerase-A-proficient Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Methiocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance methiocarb 30Jul2012 2012 doi:10.2903/j.efsa.2012.2758
+Methiocarb 217-991-2 2032-65-7 single chemical entity Component is identical to the substance Methiocarb 217-991-2 2032-65-7 3,5-dimethyl-4-(methylsulfanyl)phenyl methylcarbamate Methiocarb C11H15NO2S CNC(=O)Oc1cc(C)c(SC)c(C)c1 InChI=1/C11H15NO2S/c1-7-5-9(14-11(13)12-3)6-8(2)10(7)15-4/h5-6H,1-4H3,(H,12,13) organic compound Other Other gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) DNA-polymerase-A-proficient Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Methiocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance methiocarb 30Jul2012 2012 doi:10.2903/j.efsa.2012.2758
+Methiocarb 217-991-2 2032-65-7 single chemical entity Component is identical to the substance Methiocarb 217-991-2 2032-65-7 3,5-dimethyl-4-(methylsulfanyl)phenyl methylcarbamate Methiocarb C11H15NO2S CNC(=O)Oc1cc(C)c(SC)c(C)c1 InChI=1/C11H15NO2S/c1-7-5-9(14-11(13)12-3)6-8(2)10(7)15-4/h5-6H,1-4H3,(H,12,13) organic compound Other Other gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) DNA-polymerase-A-deficient Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Methiocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance methiocarb 30Jul2012 2012 doi:10.2903/j.efsa.2012.2758
+Methiocarb 217-991-2 2032-65-7 single chemical entity Component is identical to the substance Methiocarb 217-991-2 2032-65-7 3,5-dimethyl-4-(methylsulfanyl)phenyl methylcarbamate Methiocarb C11H15NO2S CNC(=O)Oc1cc(C)c(SC)c(C)c1 InChI=1/C11H15NO2S/c1-7-5-9(14-11(13)12-3)6-8(2)10(7)15-4/h5-6H,1-4H3,(H,12,13) organic compound Other Other gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) DNA-polymerase-A-deficient Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Methiocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance methiocarb 30Jul2012 2012 doi:10.2903/j.efsa.2012.2758
+Methiocarb 217-991-2 2032-65-7 single chemical entity Component is identical to the substance Methiocarb 217-991-2 2032-65-7 3,5-dimethyl-4-(methylsulfanyl)phenyl methylcarbamate Methiocarb C11H15NO2S CNC(=O)Oc1cc(C)c(SC)c(C)c1 InChI=1/C11H15NO2S/c1-7-5-9(14-11(13)12-3)6-8(2)10(7)15-4/h5-6H,1-4H3,(H,12,13) organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes without Negative RMS: The United Kingdom Methiocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance methiocarb 30Jul2012 2012 doi:10.2903/j.efsa.2012.2758
+Methiocarb 217-991-2 2032-65-7 single chemical entity Component is identical to the substance Methiocarb 217-991-2 2032-65-7 3,5-dimethyl-4-(methylsulfanyl)phenyl methylcarbamate Methiocarb C11H15NO2S CNC(=O)Oc1cc(C)c(SC)c(C)c1 InChI=1/C11H15NO2S/c1-7-5-9(14-11(13)12-3)6-8(2)10(7)15-4/h5-6H,1-4H3,(H,12,13) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes without Positive RMS: The United Kingdom Methiocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance methiocarb 30Jul2012 2012 doi:10.2903/j.efsa.2012.2758
+Methiocarb 217-991-2 2032-65-7 single chemical entity Component is identical to the substance Methiocarb 217-991-2 2032-65-7 3,5-dimethyl-4-(methylsulfanyl)phenyl methylcarbamate Methiocarb C11H15NO2S CNC(=O)Oc1cc(C)c(SC)c(C)c1 InChI=1/C11H15NO2S/c1-7-5-9(14-11(13)12-3)6-8(2)10(7)15-4/h5-6H,1-4H3,(H,12,13) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes with Positive RMS: The United Kingdom Methiocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance methiocarb 30Jul2012 2012 doi:10.2903/j.efsa.2012.2758
+Methiocarb 217-991-2 2032-65-7 single chemical entity Component is identical to the substance Methiocarb 217-991-2 2032-65-7 3,5-dimethyl-4-(methylsulfanyl)phenyl methylcarbamate Methiocarb C11H15NO2S CNC(=O)Oc1cc(C)c(SC)c(C)c1 InChI=1/C11H15NO2S/c1-7-5-9(14-11(13)12-3)6-8(2)10(7)15-4/h5-6H,1-4H3,(H,12,13) organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro According to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: The United Kingdom Methiocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance methiocarb 30Jul2012 2012 doi:10.2903/j.efsa.2012.2758
+Methiocarb 217-991-2 2032-65-7 single chemical entity Component is identical to the substance Methiocarb 217-991-2 2032-65-7 3,5-dimethyl-4-(methylsulfanyl)phenyl methylcarbamate Methiocarb C11H15NO2S CNC(=O)Oc1cc(C)c(SC)c(C)c1 InChI=1/C11H15NO2S/c1-7-5-9(14-11(13)12-3)6-8(2)10(7)15-4/h5-6H,1-4H3,(H,12,13) organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro According to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: The United Kingdom Methiocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance methiocarb 30Jul2012 2012 doi:10.2903/j.efsa.2012.2758
+Methiocarb 217-991-2 2032-65-7 single chemical entity Component is identical to the substance Methiocarb 217-991-2 2032-65-7 3,5-dimethyl-4-(methylsulfanyl)phenyl methylcarbamate Methiocarb C11H15NO2S CNC(=O)Oc1cc(C)c(SC)c(C)c1 InChI=1/C11H15NO2S/c1-7-5-9(14-11(13)12-3)6-8(2)10(7)15-4/h5-6H,1-4H3,(H,12,13) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 6.0000000000 h yes not applicable Negative indirect evidence-systemic toxicity RMS: The United Kingdom Methiocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance methiocarb 30Jul2012 2012 doi:10.2903/j.efsa.2012.2758
+Methiocarb 217-991-2 2032-65-7 single chemical entity Component is identical to the substance Methiocarb 217-991-2 2032-65-7 3,5-dimethyl-4-(methylsulfanyl)phenyl methylcarbamate Methiocarb C11H15NO2S CNC(=O)Oc1cc(C)c(SC)c(C)c1 InChI=1/C11H15NO2S/c1-7-5-9(14-11(13)12-3)6-8(2)10(7)15-4/h5-6H,1-4H3,(H,12,13) organic compound Other Other chromosome aberration dominant lethal assay in vivo According to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) No Acceptable House mouse (as animal) NMRI 50 Male oral: unspecified 48.0000000000 D yes not applicable Negative RMS: The United Kingdom Methiocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance methiocarb 30Jul2012 2012 doi:10.2903/j.efsa.2012.2758
+Pyrethrins 8003-34-7 complex product: derived from botanical sources Component is identical to the substance Pyrethrins 8003-34-7 [(1S)-2-methyl-4-oxo-3-[(2E)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1R)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropane-1-carboxylate;[2-methyl-4-oxo-3-[(2E)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1R)-3-[(E)-3-methoxy-2-methyl-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate Pyrethrins C43H56O8 CC1=C(C(=O)CC1OC(=O)C2C(C2(C)C)C=C(C)C)CC=CC=C.CC1=C(C(=O)CC1OC(=O)C2C(C2(C)C)C=C(C)C(=O)OC)CC=CC=C InChI=1S/C22H28O5.C21H28O3/c1-7-8-9-10-15-14(3)18(12-17(15)23)27-21(25)19-16(22(19,4)5)11-13(2)20(24)26-6;1-7-8-9-10-15-14(4)18(12-17(15)22)24-20(23)19-16(11-13(2)3)21(19,5)6/h7-9,11,16,18-19H,1,10,12H2,2-6H3;7-9,11,16,18-19H,1,10,12H2,2-6H3/b9-8+,13-11+;9-8+/t16?,18?,19-;16?,18-,19-/m00/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Italy Pyrethrins (Final Addendum to the DAR) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyrethrins 09Jan2013 2013 doi:10.2903/j.efsa.2013.3032
+Pyrethrins 8003-34-7 complex product: derived from botanical sources Component is identical to the substance Pyrethrins 8003-34-7 [(1S)-2-methyl-4-oxo-3-[(2E)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1R)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropane-1-carboxylate;[2-methyl-4-oxo-3-[(2E)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1R)-3-[(E)-3-methoxy-2-methyl-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate Pyrethrins C43H56O8 CC1=C(C(=O)CC1OC(=O)C2C(C2(C)C)C=C(C)C)CC=CC=C.CC1=C(C(=O)CC1OC(=O)C2C(C2(C)C)C=C(C)C(=O)OC)CC=CC=C InChI=1S/C22H28O5.C21H28O3/c1-7-8-9-10-15-14(3)18(12-17(15)23)27-21(25)19-16(22(19,4)5)11-13(2)20(24)26-6;1-7-8-9-10-15-14(4)18(12-17(15)22)24-20(23)19-16(11-13(2)3)21(19,5)6/h7-9,11,16,18-19H,1,10,12H2,2-6H3;7-9,11,16,18-19H,1,10,12H2,2-6H3/b9-8+,13-11+;9-8+/t16?,18?,19-;16?,18-,19-/m00/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Italy Pyrethrins (Final Addendum to the DAR) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyrethrins 09Jan2013 2013 doi:10.2903/j.efsa.2013.3032
+Pyrethrins 8003-34-7 complex product: derived from botanical sources Component is identical to the substance Pyrethrins 8003-34-7 [(1S)-2-methyl-4-oxo-3-[(2E)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1R)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropane-1-carboxylate;[2-methyl-4-oxo-3-[(2E)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1R)-3-[(E)-3-methoxy-2-methyl-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate Pyrethrins C43H56O8 CC1=C(C(=O)CC1OC(=O)C2C(C2(C)C)C=C(C)C)CC=CC=C.CC1=C(C(=O)CC1OC(=O)C2C(C2(C)C)C=C(C)C(=O)OC)CC=CC=C InChI=1S/C22H28O5.C21H28O3/c1-7-8-9-10-15-14(3)18(12-17(15)23)27-21(25)19-16(22(19,4)5)11-13(2)20(24)26-6;1-7-8-9-10-15-14(4)18(12-17(15)22)24-20(23)19-16(11-13(2)3)21(19,5)6/h7-9,11,16,18-19H,1,10,12H2,2-6H3;7-9,11,16,18-19H,1,10,12H2,2-6H3/b9-8+,13-11+;9-8+/t16?,18?,19-;16?,18-,19-/m00/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Italy Pyrethrins (Final Addendum to the DAR) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyrethrins 09Jan2013 2013 doi:10.2903/j.efsa.2013.3032
+Pyrethrins 8003-34-7 complex product: derived from botanical sources Component is identical to the substance Pyrethrins 8003-34-7 [(1S)-2-methyl-4-oxo-3-[(2E)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1R)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropane-1-carboxylate;[2-methyl-4-oxo-3-[(2E)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1R)-3-[(E)-3-methoxy-2-methyl-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate Pyrethrins C43H56O8 CC1=C(C(=O)CC1OC(=O)C2C(C2(C)C)C=C(C)C)CC=CC=C.CC1=C(C(=O)CC1OC(=O)C2C(C2(C)C)C=C(C)C(=O)OC)CC=CC=C InChI=1S/C22H28O5.C21H28O3/c1-7-8-9-10-15-14(3)18(12-17(15)23)27-21(25)19-16(22(19,4)5)11-13(2)20(24)26-6;1-7-8-9-10-15-14(4)18(12-17(15)22)24-20(23)19-16(11-13(2)3)21(19,5)6/h7-9,11,16,18-19H,1,10,12H2,2-6H3;7-9,11,16,18-19H,1,10,12H2,2-6H3/b9-8+,13-11+;9-8+/t16?,18?,19-;16?,18-,19-/m00/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Italy Pyrethrins (Final Addendum to the DAR) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyrethrins 09Jan2013 2013 doi:10.2903/j.efsa.2013.3032
+Pyrethrins 8003-34-7 complex product: derived from botanical sources Component is identical to the substance Pyrethrins 8003-34-7 [(1S)-2-methyl-4-oxo-3-[(2E)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1R)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropane-1-carboxylate;[2-methyl-4-oxo-3-[(2E)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1R)-3-[(E)-3-methoxy-2-methyl-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate Pyrethrins C43H56O8 CC1=C(C(=O)CC1OC(=O)C2C(C2(C)C)C=C(C)C)CC=CC=C.CC1=C(C(=O)CC1OC(=O)C2C(C2(C)C)C=C(C)C(=O)OC)CC=CC=C InChI=1S/C22H28O5.C21H28O3/c1-7-8-9-10-15-14(3)18(12-17(15)23)27-21(25)19-16(22(19,4)5)11-13(2)20(24)26-6;1-7-8-9-10-15-14(4)18(12-17(15)22)24-20(23)19-16(11-13(2)3)21(19,5)6/h7-9,11,16,18-19H,1,10,12H2,2-6H3;7-9,11,16,18-19H,1,10,12H2,2-6H3/b9-8+,13-11+;9-8+/t16?,18?,19-;16?,18-,19-/m00/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Italy Pyrethrins (Final Addendum to the DAR) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyrethrins 09Jan2013 2013 doi:10.2903/j.efsa.2013.3032
+Pyrethrins 8003-34-7 complex product: derived from botanical sources Component is identical to the substance Pyrethrins 8003-34-7 [(1S)-2-methyl-4-oxo-3-[(2E)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1R)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropane-1-carboxylate;[2-methyl-4-oxo-3-[(2E)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1R)-3-[(E)-3-methoxy-2-methyl-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate Pyrethrins C43H56O8 CC1=C(C(=O)CC1OC(=O)C2C(C2(C)C)C=C(C)C)CC=CC=C.CC1=C(C(=O)CC1OC(=O)C2C(C2(C)C)C=C(C)C(=O)OC)CC=CC=C InChI=1S/C22H28O5.C21H28O3/c1-7-8-9-10-15-14(3)18(12-17(15)23)27-21(25)19-16(22(19,4)5)11-13(2)20(24)26-6;1-7-8-9-10-15-14(4)18(12-17(15)22)24-20(23)19-16(11-13(2)3)21(19,5)6/h7-9,11,16,18-19H,1,10,12H2,2-6H3;7-9,11,16,18-19H,1,10,12H2,2-6H3/b9-8+,13-11+;9-8+/t16?,18?,19-;16?,18-,19-/m00/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Italy Pyrethrins (Final Addendum to the DAR) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyrethrins 09Jan2013 2013 doi:10.2903/j.efsa.2013.3032
+Pyrethrins 8003-34-7 complex product: derived from botanical sources Component is identical to the substance Pyrethrins 8003-34-7 [(1S)-2-methyl-4-oxo-3-[(2E)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1R)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropane-1-carboxylate;[2-methyl-4-oxo-3-[(2E)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1R)-3-[(E)-3-methoxy-2-methyl-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate Pyrethrins C43H56O8 CC1=C(C(=O)CC1OC(=O)C2C(C2(C)C)C=C(C)C)CC=CC=C.CC1=C(C(=O)CC1OC(=O)C2C(C2(C)C)C=C(C)C(=O)OC)CC=CC=C InChI=1S/C22H28O5.C21H28O3/c1-7-8-9-10-15-14(3)18(12-17(15)23)27-21(25)19-16(22(19,4)5)11-13(2)20(24)26-6;1-7-8-9-10-15-14(4)18(12-17(15)22)24-20(23)19-16(11-13(2)3)21(19,5)6/h7-9,11,16,18-19H,1,10,12H2,2-6H3;7-9,11,16,18-19H,1,10,12H2,2-6H3/b9-8+,13-11+;9-8+/t16?,18?,19-;16?,18-,19-/m00/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Italy Pyrethrins (Final Addendum to the DAR) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyrethrins 09Jan2013 2013 doi:10.2903/j.efsa.2013.3032
+Pyrethrins 8003-34-7 complex product: derived from botanical sources Component is identical to the substance Pyrethrins 8003-34-7 [(1S)-2-methyl-4-oxo-3-[(2E)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1R)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropane-1-carboxylate;[2-methyl-4-oxo-3-[(2E)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1R)-3-[(E)-3-methoxy-2-methyl-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate Pyrethrins C43H56O8 CC1=C(C(=O)CC1OC(=O)C2C(C2(C)C)C=C(C)C)CC=CC=C.CC1=C(C(=O)CC1OC(=O)C2C(C2(C)C)C=C(C)C(=O)OC)CC=CC=C InChI=1S/C22H28O5.C21H28O3/c1-7-8-9-10-15-14(3)18(12-17(15)23)27-21(25)19-16(22(19,4)5)11-13(2)20(24)26-6;1-7-8-9-10-15-14(4)18(12-17(15)22)24-20(23)19-16(11-13(2)3)21(19,5)6/h7-9,11,16,18-19H,1,10,12H2,2-6H3;7-9,11,16,18-19H,1,10,12H2,2-6H3/b9-8+,13-11+;9-8+/t16?,18?,19-;16?,18-,19-/m00/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Italy Pyrethrins (Final Addendum to the DAR) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyrethrins 09Jan2013 2013 doi:10.2903/j.efsa.2013.3032
+Pyrethrins 8003-34-7 complex product: derived from botanical sources Component is identical to the substance Pyrethrins 8003-34-7 [(1S)-2-methyl-4-oxo-3-[(2E)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1R)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropane-1-carboxylate;[2-methyl-4-oxo-3-[(2E)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1R)-3-[(E)-3-methoxy-2-methyl-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate Pyrethrins C43H56O8 CC1=C(C(=O)CC1OC(=O)C2C(C2(C)C)C=C(C)C)CC=CC=C.CC1=C(C(=O)CC1OC(=O)C2C(C2(C)C)C=C(C)C(=O)OC)CC=CC=C InChI=1S/C22H28O5.C21H28O3/c1-7-8-9-10-15-14(3)18(12-17(15)23)27-21(25)19-16(22(19,4)5)11-13(2)20(24)26-6;1-7-8-9-10-15-14(4)18(12-17(15)22)24-20(23)19-16(11-13(2)3)21(19,5)6/h7-9,11,16,18-19H,1,10,12H2,2-6H3;7-9,11,16,18-19H,1,10,12H2,2-6H3/b9-8+,13-11+;9-8+/t16?,18?,19-;16?,18-,19-/m00/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Italy Pyrethrins (Final Addendum to the DAR) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyrethrins 09Jan2013 2013 doi:10.2903/j.efsa.2013.3032
+Pyrethrins 8003-34-7 complex product: derived from botanical sources Component is identical to the substance Pyrethrins 8003-34-7 [(1S)-2-methyl-4-oxo-3-[(2E)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1R)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropane-1-carboxylate;[2-methyl-4-oxo-3-[(2E)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1R)-3-[(E)-3-methoxy-2-methyl-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate Pyrethrins C43H56O8 CC1=C(C(=O)CC1OC(=O)C2C(C2(C)C)C=C(C)C)CC=CC=C.CC1=C(C(=O)CC1OC(=O)C2C(C2(C)C)C=C(C)C(=O)OC)CC=CC=C InChI=1S/C22H28O5.C21H28O3/c1-7-8-9-10-15-14(3)18(12-17(15)23)27-21(25)19-16(22(19,4)5)11-13(2)20(24)26-6;1-7-8-9-10-15-14(4)18(12-17(15)22)24-20(23)19-16(11-13(2)3)21(19,5)6/h7-9,11,16,18-19H,1,10,12H2,2-6H3;7-9,11,16,18-19H,1,10,12H2,2-6H3/b9-8+,13-11+;9-8+/t16?,18?,19-;16?,18-,19-/m00/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Italy Pyrethrins (Final Addendum to the DAR) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyrethrins 09Jan2013 2013 doi:10.2903/j.efsa.2013.3032
+Pyrethrins 8003-34-7 complex product: derived from botanical sources Component is identical to the substance Pyrethrins 8003-34-7 [(1S)-2-methyl-4-oxo-3-[(2E)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1R)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropane-1-carboxylate;[2-methyl-4-oxo-3-[(2E)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1R)-3-[(E)-3-methoxy-2-methyl-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate Pyrethrins C43H56O8 CC1=C(C(=O)CC1OC(=O)C2C(C2(C)C)C=C(C)C)CC=CC=C.CC1=C(C(=O)CC1OC(=O)C2C(C2(C)C)C=C(C)C(=O)OC)CC=CC=C InChI=1S/C22H28O5.C21H28O3/c1-7-8-9-10-15-14(3)18(12-17(15)23)27-21(25)19-16(22(19,4)5)11-13(2)20(24)26-6;1-7-8-9-10-15-14(4)18(12-17(15)22)24-20(23)19-16(11-13(2)3)21(19,5)6/h7-9,11,16,18-19H,1,10,12H2,2-6H3;7-9,11,16,18-19H,1,10,12H2,2-6H3/b9-8+,13-11+;9-8+/t16?,18?,19-;16?,18-,19-/m00/s1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: Italy Pyrethrins (Final Addendum to the DAR) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyrethrins 09Jan2013 2013 doi:10.2903/j.efsa.2013.3032
+Pyrethrins 8003-34-7 complex product: derived from botanical sources Component is identical to the substance Pyrethrins 8003-34-7 [(1S)-2-methyl-4-oxo-3-[(2E)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1R)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropane-1-carboxylate;[2-methyl-4-oxo-3-[(2E)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1R)-3-[(E)-3-methoxy-2-methyl-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate Pyrethrins C43H56O8 CC1=C(C(=O)CC1OC(=O)C2C(C2(C)C)C=C(C)C)CC=CC=C.CC1=C(C(=O)CC1OC(=O)C2C(C2(C)C)C=C(C)C(=O)OC)CC=CC=C InChI=1S/C22H28O5.C21H28O3/c1-7-8-9-10-15-14(3)18(12-17(15)23)27-21(25)19-16(22(19,4)5)11-13(2)20(24)26-6;1-7-8-9-10-15-14(4)18(12-17(15)22)24-20(23)19-16(11-13(2)3)21(19,5)6/h7-9,11,16,18-19H,1,10,12H2,2-6H3;7-9,11,16,18-19H,1,10,12H2,2-6H3/b9-8+,13-11+;9-8+/t16?,18?,19-;16?,18-,19-/m00/s1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: Italy Pyrethrins (Final Addendum to the DAR) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyrethrins 09Jan2013 2013 doi:10.2903/j.efsa.2013.3032
+Pyrethrins 8003-34-7 complex product: derived from botanical sources Component is identical to the substance Pyrethrins 8003-34-7 [(1S)-2-methyl-4-oxo-3-[(2E)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1R)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropane-1-carboxylate;[2-methyl-4-oxo-3-[(2E)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1R)-3-[(E)-3-methoxy-2-methyl-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate Pyrethrins C43H56O8 CC1=C(C(=O)CC1OC(=O)C2C(C2(C)C)C=C(C)C)CC=CC=C.CC1=C(C(=O)CC1OC(=O)C2C(C2(C)C)C=C(C)C(=O)OC)CC=CC=C InChI=1S/C22H28O5.C21H28O3/c1-7-8-9-10-15-14(3)18(12-17(15)23)27-21(25)19-16(22(19,4)5)11-13(2)20(24)26-6;1-7-8-9-10-15-14(4)18(12-17(15)22)24-20(23)19-16(11-13(2)3)21(19,5)6/h7-9,11,16,18-19H,1,10,12H2,2-6H3;7-9,11,16,18-19H,1,10,12H2,2-6H3/b9-8+,13-11+;9-8+/t16?,18?,19-;16?,18-,19-/m00/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Italy Pyrethrins (Final Addendum to the DAR) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyrethrins 09Jan2013 2013 doi:10.2903/j.efsa.2013.3032
+Pyrethrins 8003-34-7 complex product: derived from botanical sources Component is identical to the substance Pyrethrins 8003-34-7 [(1S)-2-methyl-4-oxo-3-[(2E)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1R)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropane-1-carboxylate;[2-methyl-4-oxo-3-[(2E)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1R)-3-[(E)-3-methoxy-2-methyl-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate Pyrethrins C43H56O8 CC1=C(C(=O)CC1OC(=O)C2C(C2(C)C)C=C(C)C)CC=CC=C.CC1=C(C(=O)CC1OC(=O)C2C(C2(C)C)C=C(C)C(=O)OC)CC=CC=C InChI=1S/C22H28O5.C21H28O3/c1-7-8-9-10-15-14(3)18(12-17(15)23)27-21(25)19-16(22(19,4)5)11-13(2)20(24)26-6;1-7-8-9-10-15-14(4)18(12-17(15)22)24-20(23)19-16(11-13(2)3)21(19,5)6/h7-9,11,16,18-19H,1,10,12H2,2-6H3;7-9,11,16,18-19H,1,10,12H2,2-6H3/b9-8+,13-11+;9-8+/t16?,18?,19-;16?,18-,19-/m00/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Italy Pyrethrins (Final Addendum to the DAR) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyrethrins 09Jan2013 2013 doi:10.2903/j.efsa.2013.3032
+Pyrethrins 8003-34-7 complex product: derived from botanical sources Component is identical to the substance Pyrethrins 8003-34-7 [(1S)-2-methyl-4-oxo-3-[(2E)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1R)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropane-1-carboxylate;[2-methyl-4-oxo-3-[(2E)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1R)-3-[(E)-3-methoxy-2-methyl-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate Pyrethrins C43H56O8 CC1=C(C(=O)CC1OC(=O)C2C(C2(C)C)C=C(C)C)CC=CC=C.CC1=C(C(=O)CC1OC(=O)C2C(C2(C)C)C=C(C)C(=O)OC)CC=CC=C InChI=1S/C22H28O5.C21H28O3/c1-7-8-9-10-15-14(3)18(12-17(15)23)27-21(25)19-16(22(19,4)5)11-13(2)20(24)26-6;1-7-8-9-10-15-14(4)18(12-17(15)22)24-20(23)19-16(11-13(2)3)21(19,5)6/h7-9,11,16,18-19H,1,10,12H2,2-6H3;7-9,11,16,18-19H,1,10,12H2,2-6H3/b9-8+,13-11+;9-8+/t16?,18?,19-;16?,18-,19-/m00/s1 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Italy Pyrethrins (Final Addendum to the DAR) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyrethrins 09Jan2013 2013 doi:10.2903/j.efsa.2013.3032
+Metamitron 255-349-3 41394-05-2 single chemical entity Component is identical to the substance Metamitron 255-349-3 41394-05-2 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one Metamitron C10H10N4O O=C1C(C2=CC=CC=C2)=NN=C(C)N1N InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metamitron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron 22Oct2008 2008 doi:10.2903/j.efsa.2008.185r
+Metamitron 255-349-3 41394-05-2 single chemical entity Component is identical to the substance Metamitron 255-349-3 41394-05-2 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one Metamitron C10H10N4O O=C1C(C2=CC=CC=C2)=NN=C(C)N1N InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metamitron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron 22Oct2008 2008 doi:10.2903/j.efsa.2008.185r
+Metamitron 255-349-3 41394-05-2 single chemical entity Component is identical to the substance Metamitron 255-349-3 41394-05-2 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one Metamitron C10H10N4O O=C1C(C2=CC=CC=C2)=NN=C(C)N1N InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metamitron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron 22Oct2008 2008 doi:10.2903/j.efsa.2008.185r
+Metamitron 255-349-3 41394-05-2 single chemical entity Component is identical to the substance Metamitron 255-349-3 41394-05-2 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one Metamitron C10H10N4O O=C1C(C2=CC=CC=C2)=NN=C(C)N1N InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metamitron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron 22Oct2008 2008 doi:10.2903/j.efsa.2008.185r
+Metamitron 255-349-3 41394-05-2 single chemical entity Component is identical to the substance Metamitron 255-349-3 41394-05-2 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one Metamitron C10H10N4O O=C1C(C2=CC=CC=C2)=NN=C(C)N1N InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metamitron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron 22Oct2008 2008 doi:10.2903/j.efsa.2008.185r
+Metamitron 255-349-3 41394-05-2 single chemical entity Component is identical to the substance Metamitron 255-349-3 41394-05-2 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one Metamitron C10H10N4O O=C1C(C2=CC=CC=C2)=NN=C(C)N1N InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metamitron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron 22Oct2008 2008 doi:10.2903/j.efsa.2008.185r
+Metamitron 255-349-3 41394-05-2 single chemical entity Component is identical to the substance Metamitron 255-349-3 41394-05-2 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one Metamitron C10H10N4O O=C1C(C2=CC=CC=C2)=NN=C(C)N1N InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metamitron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron 22Oct2008 2008 doi:10.2903/j.efsa.2008.185r
+Metamitron 255-349-3 41394-05-2 single chemical entity Component is identical to the substance Metamitron 255-349-3 41394-05-2 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one Metamitron C10H10N4O O=C1C(C2=CC=CC=C2)=NN=C(C)N1N InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metamitron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron 22Oct2008 2008 doi:10.2903/j.efsa.2008.185r
+Metamitron 255-349-3 41394-05-2 single chemical entity Component is identical to the substance Metamitron 255-349-3 41394-05-2 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one Metamitron C10H10N4O O=C1C(C2=CC=CC=C2)=NN=C(C)N1N InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metamitron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron 22Oct2008 2008 doi:10.2903/j.efsa.2008.185r
+Metamitron 255-349-3 41394-05-2 single chemical entity Component is identical to the substance Metamitron 255-349-3 41394-05-2 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one Metamitron C10H10N4O O=C1C(C2=CC=CC=C2)=NN=C(C)N1N InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metamitron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron 22Oct2008 2008 doi:10.2903/j.efsa.2008.185r
+Metamitron 255-349-3 41394-05-2 single chemical entity Component is identical to the substance Metamitron 255-349-3 41394-05-2 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one Metamitron C10H10N4O O=C1C(C2=CC=CC=C2)=NN=C(C)N1N InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metamitron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron 22Oct2008 2008 doi:10.2903/j.efsa.2008.185r
+Metamitron 255-349-3 41394-05-2 single chemical entity Component is identical to the substance Metamitron 255-349-3 41394-05-2 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one Metamitron C10H10N4O O=C1C(C2=CC=CC=C2)=NN=C(C)N1N InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metamitron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron 22Oct2008 2008 doi:10.2903/j.efsa.2008.185r
+Metamitron 255-349-3 41394-05-2 single chemical entity Component is identical to the substance Metamitron 255-349-3 41394-05-2 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one Metamitron C10H10N4O O=C1C(C2=CC=CC=C2)=NN=C(C)N1N InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metamitron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron 22Oct2008 2008 doi:10.2903/j.efsa.2008.185r
+Metamitron 255-349-3 41394-05-2 single chemical entity Component is identical to the substance Metamitron 255-349-3 41394-05-2 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one Metamitron C10H10N4O O=C1C(C2=CC=CC=C2)=NN=C(C)N1N InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metamitron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron 22Oct2008 2008 doi:10.2903/j.efsa.2008.185r
+Metamitron 255-349-3 41394-05-2 single chemical entity Component is identical to the substance Metamitron 255-349-3 41394-05-2 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one Metamitron C10H10N4O O=C1C(C2=CC=CC=C2)=NN=C(C)N1N InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metamitron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron 22Oct2008 2008 doi:10.2903/j.efsa.2008.185r
+Metamitron 255-349-3 41394-05-2 single chemical entity Component is identical to the substance Metamitron 255-349-3 41394-05-2 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one Metamitron C10H10N4O O=C1C(C2=CC=CC=C2)=NN=C(C)N1N InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metamitron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron 22Oct2008 2008 doi:10.2903/j.efsa.2008.185r
+Metamitron 255-349-3 41394-05-2 single chemical entity Component is identical to the substance Metamitron 255-349-3 41394-05-2 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one Metamitron C10H10N4O O=C1C(C2=CC=CC=C2)=NN=C(C)N1N InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metamitron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron 22Oct2008 2008 doi:10.2903/j.efsa.2008.185r
+Metamitron 255-349-3 41394-05-2 single chemical entity Component is identical to the substance Metamitron 255-349-3 41394-05-2 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one Metamitron C10H10N4O O=C1C(C2=CC=CC=C2)=NN=C(C)N1N InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metamitron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron 22Oct2008 2008 doi:10.2903/j.efsa.2008.185r
+Metamitron 255-349-3 41394-05-2 single chemical entity Component is identical to the substance Metamitron 255-349-3 41394-05-2 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one Metamitron C10H10N4O O=C1C(C2=CC=CC=C2)=NN=C(C)N1N InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metamitron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron 22Oct2008 2008 doi:10.2903/j.efsa.2008.185r
+Metamitron 255-349-3 41394-05-2 single chemical entity Component is identical to the substance Metamitron 255-349-3 41394-05-2 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one Metamitron C10H10N4O O=C1C(C2=CC=CC=C2)=NN=C(C)N1N InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metamitron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron 22Oct2008 2008 doi:10.2903/j.efsa.2008.185r
+Metamitron 255-349-3 41394-05-2 single chemical entity Component is identical to the substance Metamitron 255-349-3 41394-05-2 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one Metamitron C10H10N4O O=C1C(C2=CC=CC=C2)=NN=C(C)N1N InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metamitron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron 22Oct2008 2008 doi:10.2903/j.efsa.2008.185r
+Metamitron 255-349-3 41394-05-2 single chemical entity Component is identical to the substance Metamitron 255-349-3 41394-05-2 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one Metamitron C10H10N4O O=C1C(C2=CC=CC=C2)=NN=C(C)N1N InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metamitron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron 22Oct2008 2008 doi:10.2903/j.efsa.2008.185r
+Metamitron 255-349-3 41394-05-2 single chemical entity Component is identical to the substance Metamitron 255-349-3 41394-05-2 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one Metamitron C10H10N4O O=C1C(C2=CC=CC=C2)=NN=C(C)N1N InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: The United Kingdom Metamitron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron 22Oct2008 2008 doi:10.2903/j.efsa.2008.185r
+Metamitron 255-349-3 41394-05-2 single chemical entity Component is identical to the substance Metamitron 255-349-3 41394-05-2 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one Metamitron C10H10N4O O=C1C(C2=CC=CC=C2)=NN=C(C)N1N InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: The United Kingdom Metamitron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron 22Oct2008 2008 doi:10.2903/j.efsa.2008.185r
+Metamitron 255-349-3 41394-05-2 single chemical entity Component is identical to the substance Metamitron 255-349-3 41394-05-2 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one Metamitron C10H10N4O O=C1C(C2=CC=CC=C2)=NN=C(C)N1N InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: The United Kingdom Metamitron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron 22Oct2008 2008 doi:10.2903/j.efsa.2008.185r
+Metamitron 255-349-3 41394-05-2 single chemical entity Component is identical to the substance Metamitron 255-349-3 41394-05-2 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one Metamitron C10H10N4O O=C1C(C2=CC=CC=C2)=NN=C(C)N1N InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: The United Kingdom Metamitron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron 22Oct2008 2008 doi:10.2903/j.efsa.2008.185r
+Metamitron 255-349-3 41394-05-2 single chemical entity Component is identical to the substance Metamitron 255-349-3 41394-05-2 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one Metamitron C10H10N4O O=C1C(C2=CC=CC=C2)=NN=C(C)N1N InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: The United Kingdom Metamitron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron 22Oct2008 2008 doi:10.2903/j.efsa.2008.185r
+Metamitron 255-349-3 41394-05-2 single chemical entity Component is identical to the substance Metamitron 255-349-3 41394-05-2 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one Metamitron C10H10N4O O=C1C(C2=CC=CC=C2)=NN=C(C)N1N InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: The United Kingdom Metamitron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron 22Oct2008 2008 doi:10.2903/j.efsa.2008.185r
+Metamitron 255-349-3 41394-05-2 single chemical entity Component is identical to the substance Metamitron 255-349-3 41394-05-2 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one Metamitron C10H10N4O O=C1C(C2=CC=CC=C2)=NN=C(C)N1N InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: The United Kingdom Metamitron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron 22Oct2008 2008 doi:10.2903/j.efsa.2008.185r
+Metamitron 255-349-3 41394-05-2 single chemical entity Component is identical to the substance Metamitron 255-349-3 41394-05-2 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one Metamitron C10H10N4O O=C1C(C2=CC=CC=C2)=NN=C(C)N1N InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: The United Kingdom Metamitron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron 22Oct2008 2008 doi:10.2903/j.efsa.2008.185r
+Metamitron 255-349-3 41394-05-2 single chemical entity Component is identical to the substance Metamitron 255-349-3 41394-05-2 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one Metamitron C10H10N4O O=C1C(C2=CC=CC=C2)=NN=C(C)N1N InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: The United Kingdom Metamitron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron 22Oct2008 2008 doi:10.2903/j.efsa.2008.185r
+Metamitron 255-349-3 41394-05-2 single chemical entity Component is identical to the substance Metamitron 255-349-3 41394-05-2 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one Metamitron C10H10N4O O=C1C(C2=CC=CC=C2)=NN=C(C)N1N InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: The United Kingdom Metamitron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron 22Oct2008 2008 doi:10.2903/j.efsa.2008.185r
+Metamitron 255-349-3 41394-05-2 single chemical entity Component is identical to the substance Metamitron 255-349-3 41394-05-2 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one Metamitron C10H10N4O O=C1C(C2=CC=CC=C2)=NN=C(C)N1N InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3 organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metamitron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron 22Oct2008 2008 doi:10.2903/j.efsa.2008.185r
+Metamitron 255-349-3 41394-05-2 single chemical entity Component is identical to the substance Metamitron 255-349-3 41394-05-2 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one Metamitron C10H10N4O O=C1C(C2=CC=CC=C2)=NN=C(C)N1N InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3 organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metamitron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron 22Oct2008 2008 doi:10.2903/j.efsa.2008.185r
+Metamitron 255-349-3 41394-05-2 single chemical entity Component is identical to the substance Metamitron 255-349-3 41394-05-2 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one Metamitron C10H10N4O O=C1C(C2=CC=CC=C2)=NN=C(C)N1N InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3 organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metamitron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron 22Oct2008 2008 doi:10.2903/j.efsa.2008.185r
+Metamitron 255-349-3 41394-05-2 single chemical entity Component is identical to the substance Metamitron 255-349-3 41394-05-2 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one Metamitron C10H10N4O O=C1C(C2=CC=CC=C2)=NN=C(C)N1N InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3 organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metamitron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron 22Oct2008 2008 doi:10.2903/j.efsa.2008.185r
+Metamitron 255-349-3 41394-05-2 single chemical entity Component is identical to the substance Metamitron 255-349-3 41394-05-2 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one Metamitron C10H10N4O O=C1C(C2=CC=CC=C2)=NN=C(C)N1N InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3 organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metamitron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron 22Oct2008 2008 doi:10.2903/j.efsa.2008.185r
+Metamitron 255-349-3 41394-05-2 single chemical entity Component is identical to the substance Metamitron 255-349-3 41394-05-2 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one Metamitron C10H10N4O O=C1C(C2=CC=CC=C2)=NN=C(C)N1N InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3 organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metamitron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron 22Oct2008 2008 doi:10.2903/j.efsa.2008.185r
+Metamitron 255-349-3 41394-05-2 single chemical entity Component is identical to the substance Metamitron 255-349-3 41394-05-2 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one Metamitron C10H10N4O O=C1C(C2=CC=CC=C2)=NN=C(C)N1N InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3 organic compound Other Other DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) (k12)p3478 Not reported yes with Negative RMS: The United Kingdom Metamitron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron 22Oct2008 2008 doi:10.2903/j.efsa.2008.185r
+Metamitron 255-349-3 41394-05-2 single chemical entity Component is identical to the substance Metamitron 255-349-3 41394-05-2 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one Metamitron C10H10N4O O=C1C(C2=CC=CC=C2)=NN=C(C)N1N InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3 organic compound Other Other DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) W3110 Not reported yes with Negative RMS: The United Kingdom Metamitron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron 22Oct2008 2008 doi:10.2903/j.efsa.2008.185r
+Metamitron 255-349-3 41394-05-2 single chemical entity Component is identical to the substance Metamitron 255-349-3 41394-05-2 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one Metamitron C10H10N4O O=C1C(C2=CC=CC=C2)=NN=C(C)N1N InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3 organic compound Other Other DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) (k12)p3478 Not reported yes without Negative RMS: The United Kingdom Metamitron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron 22Oct2008 2008 doi:10.2903/j.efsa.2008.185r
+Metamitron 255-349-3 41394-05-2 single chemical entity Component is identical to the substance Metamitron 255-349-3 41394-05-2 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one Metamitron C10H10N4O O=C1C(C2=CC=CC=C2)=NN=C(C)N1N InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3 organic compound Other Other DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) W3110 Not reported yes without Negative RMS: The United Kingdom Metamitron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron 22Oct2008 2008 doi:10.2903/j.efsa.2008.185r
+Metamitron 255-349-3 41394-05-2 single chemical entity Component is identical to the substance Metamitron 255-349-3 41394-05-2 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one Metamitron C10H10N4O O=C1C(C2=CC=CC=C2)=NN=C(C)N1N InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3 organic compound Other Other genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro According to OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay) No Acceptable Saccharomyces cerevisiae (as organism) D7 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metamitron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron 22Oct2008 2008 doi:10.2903/j.efsa.2008.185r
+Metamitron 255-349-3 41394-05-2 single chemical entity Component is identical to the substance Metamitron 255-349-3 41394-05-2 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one Metamitron C10H10N4O O=C1C(C2=CC=CC=C2)=NN=C(C)N1N InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3 organic compound Other Other genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro According to OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay) No Acceptable Saccharomyces cerevisiae (as organism) D7 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metamitron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron 22Oct2008 2008 doi:10.2903/j.efsa.2008.185r
+Metamitron 255-349-3 41394-05-2 single chemical entity Component is identical to the substance Metamitron 255-349-3 41394-05-2 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one Metamitron C10H10N4O O=C1C(C2=CC=CC=C2)=NN=C(C)N1N InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Positive RMS: The United Kingdom Metamitron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron 22Oct2008 2008 doi:10.2903/j.efsa.2008.185r
+Metamitron 255-349-3 41394-05-2 single chemical entity Component is identical to the substance Metamitron 255-349-3 41394-05-2 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one Metamitron C10H10N4O O=C1C(C2=CC=CC=C2)=NN=C(C)N1N InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Positive RMS: The United Kingdom Metamitron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron 22Oct2008 2008 doi:10.2903/j.efsa.2008.185r
+Metamitron 255-349-3 41394-05-2 single chemical entity Component is identical to the substance Metamitron 255-349-3 41394-05-2 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one Metamitron C10H10N4O O=C1C(C2=CC=CC=C2)=NN=C(C)N1N InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metamitron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron 22Oct2008 2008 doi:10.2903/j.efsa.2008.185r
+Metamitron 255-349-3 41394-05-2 single chemical entity Component is identical to the substance Metamitron 255-349-3 41394-05-2 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one Metamitron C10H10N4O O=C1C(C2=CC=CC=C2)=NN=C(C)N1N InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metamitron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron 22Oct2008 2008 doi:10.2903/j.efsa.2008.185r
+Metamitron 255-349-3 41394-05-2 single chemical entity Component is identical to the substance Metamitron 255-349-3 41394-05-2 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one Metamitron C10H10N4O O=C1C(C2=CC=CC=C2)=NN=C(C)N1N InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Negative RMS: The United Kingdom Metamitron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron 22Oct2008 2008 doi:10.2903/j.efsa.2008.185r
+Metamitron 255-349-3 41394-05-2 single chemical entity Component is identical to the substance Metamitron 255-349-3 41394-05-2 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one Metamitron C10H10N4O O=C1C(C2=CC=CC=C2)=NN=C(C)N1N InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: The United Kingdom Metamitron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron 22Oct2008 2008 doi:10.2903/j.efsa.2008.185r
+Metamitron 255-349-3 41394-05-2 single chemical entity Component is identical to the substance Metamitron 255-349-3 41394-05-2 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one Metamitron C10H10N4O O=C1C(C2=CC=CC=C2)=NN=C(C)N1N InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 5 Male intraperitoneal 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: The United Kingdom Metamitron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron 22Oct2008 2008 doi:10.2903/j.efsa.2008.185r
+Metamitron 255-349-3 41394-05-2 single chemical entity Component is identical to the substance Metamitron 255-349-3 41394-05-2 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one Metamitron C10H10N4O O=C1C(C2=CC=CC=C2)=NN=C(C)N1N InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 6.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The United Kingdom Metamitron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron 22Oct2008 2008 doi:10.2903/j.efsa.2008.185r
+Metamitron 255-349-3 41394-05-2 single chemical entity Component is identical to the substance Metamitron 255-349-3 41394-05-2 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one Metamitron C10H10N4O O=C1C(C2=CC=CC=C2)=NN=C(C)N1N InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Swiss 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity$indirect evidence-systemic toxicity RMS: The United Kingdom Metamitron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron 22Oct2008 2008 doi:10.2903/j.efsa.2008.185r
+Metamitron 255-349-3 41394-05-2 single chemical entity Component is identical to the substance Metamitron 255-349-3 41394-05-2 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one Metamitron C10H10N4O O=C1C(C2=CC=CC=C2)=NN=C(C)N1N InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable House mouse (as animal) Swiss 10 Male/Female oral: gavage 25.5000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Metamitron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron 22Oct2008 2008 doi:10.2903/j.efsa.2008.185r
+Metamitron 255-349-3 41394-05-2 single chemical entity Component is identical to the substance Metamitron 255-349-3 41394-05-2 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one Metamitron C10H10N4O O=C1C(C2=CC=CC=C2)=NN=C(C)N1N InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Swiss 10 Male/Female oral: gavage 25.5000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The United Kingdom Metamitron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron 22Oct2008 2008 doi:10.2903/j.efsa.2008.185r
+Metamitron 255-349-3 41394-05-2 single chemical entity Component is identical to the substance Metamitron 255-349-3 41394-05-2 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one Metamitron C10H10N4O O=C1C(C2=CC=CC=C2)=NN=C(C)N1N InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3 organic compound Other Other chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) Yes Acceptable House mouse (as animal) NMRI 50 Male oral: gavage yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Metamitron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron 22Oct2008 2008 doi:10.2903/j.efsa.2008.185r
+Metamitron 255-349-3 41394-05-2 single chemical entity Component is identical to the substance Metamitron 255-349-3 41394-05-2 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one Metamitron C10H10N4O O=C1C(C2=CC=CC=C2)=NN=C(C)N1N InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3 organic compound Other Other chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) Yes Acceptable Rat (as animal) Wistar 30 Male oral: gavage 10.0000000000 D yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Metamitron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron 22Oct2008 2008 doi:10.2903/j.efsa.2008.185r
+Metamitron 255-349-3 41394-05-2 single chemical entity Component is a metabolite of the substance 3-methyl-4-amino-6-phenyl-1,2,4-triazine-5-one-oxide 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one 1-oxide Not in list C10H10N4O2 O=C2C(c1ccccc1)=[N+]([O-])N=C(C)N2N InChI=1/C10H10N4O2/c1-7-12-14(16)9(10(15)13(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Positive RMS: The United Kingdom Metamitron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron 22Oct2008 2008 doi:10.2903/j.efsa.2008.185r
+Metamitron 255-349-3 41394-05-2 single chemical entity Component is a metabolite of the substance 3-methyl-4-amino-6-phenyl-1,2,4-triazine-5-one-oxide 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one 1-oxide Not in list C10H10N4O2 O=C2C(c1ccccc1)=[N+]([O-])N=C(C)N2N InChI=1/C10H10N4O2/c1-7-12-14(16)9(10(15)13(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Positive RMS: The United Kingdom Metamitron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron 22Oct2008 2008 doi:10.2903/j.efsa.2008.185r
+Metamitron 255-349-3 41394-05-2 single chemical entity Component is a metabolite of the substance 3-methyl-4-amino-6-phenyl-1,2,4-triazine-5-one-oxide 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one 1-oxide Not in list C10H10N4O2 O=C2C(c1ccccc1)=[N+]([O-])N=C(C)N2N InChI=1/C10H10N4O2/c1-7-12-14(16)9(10(15)13(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Positive RMS: The United Kingdom Metamitron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron 22Oct2008 2008 doi:10.2903/j.efsa.2008.185r
+Metamitron 255-349-3 41394-05-2 single chemical entity Component is a metabolite of the substance 3-methyl-4-amino-6-phenyl-1,2,4-triazine-5-one-oxide 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one 1-oxide Not in list C10H10N4O2 O=C2C(c1ccccc1)=[N+]([O-])N=C(C)N2N InChI=1/C10H10N4O2/c1-7-12-14(16)9(10(15)13(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Positive RMS: The United Kingdom Metamitron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron 22Oct2008 2008 doi:10.2903/j.efsa.2008.185r
+Metamitron 255-349-3 41394-05-2 single chemical entity Component is a metabolite of the substance 3-methyl-4-amino-6-phenyl-1,2,4-triazine-5-one-oxide 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one 1-oxide Not in list C10H10N4O2 O=C2C(c1ccccc1)=[N+]([O-])N=C(C)N2N InChI=1/C10H10N4O2/c1-7-12-14(16)9(10(15)13(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Positive RMS: The United Kingdom Metamitron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron 22Oct2008 2008 doi:10.2903/j.efsa.2008.185r
+Metamitron 255-349-3 41394-05-2 single chemical entity Component is a metabolite of the substance 3-methyl-4-amino-6-phenyl-1,2,4-triazine-5-one-oxide 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one 1-oxide Not in list C10H10N4O2 O=C2C(c1ccccc1)=[N+]([O-])N=C(C)N2N InChI=1/C10H10N4O2/c1-7-12-14(16)9(10(15)13(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Positive RMS: The United Kingdom Metamitron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron 22Oct2008 2008 doi:10.2903/j.efsa.2008.185r
+Metamitron 255-349-3 41394-05-2 single chemical entity Component is a metabolite of the substance 3-methyl-4-amino-6-phenyl-1,2,4-triazine-5-one-oxide 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one 1-oxide Not in list C10H10N4O2 O=C2C(c1ccccc1)=[N+]([O-])N=C(C)N2N InChI=1/C10H10N4O2/c1-7-12-14(16)9(10(15)13(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metamitron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron 22Oct2008 2008 doi:10.2903/j.efsa.2008.185r
+Metamitron 255-349-3 41394-05-2 single chemical entity Component is a metabolite of the substance 3-methyl-4-amino-6-phenyl-1,2,4-triazine-5-one-oxide 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one 1-oxide Not in list C10H10N4O2 O=C2C(c1ccccc1)=[N+]([O-])N=C(C)N2N InChI=1/C10H10N4O2/c1-7-12-14(16)9(10(15)13(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metamitron 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron 22Oct2008 2008 doi:10.2903/j.efsa.2008.185r
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is identical to the substance Metalaxyl-M 615-135-6 70630-17-0 methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate Metalaxyl-M C15H21NO4 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is identical to the substance Metalaxyl-M 615-135-6 70630-17-0 methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate Metalaxyl-M C15H21NO4 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is identical to the substance Metalaxyl-M 615-135-6 70630-17-0 methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate Metalaxyl-M C15H21NO4 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is identical to the substance Metalaxyl-M 615-135-6 70630-17-0 methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate Metalaxyl-M C15H21NO4 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is identical to the substance Metalaxyl-M 615-135-6 70630-17-0 methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate Metalaxyl-M C15H21NO4 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is identical to the substance Metalaxyl-M 615-135-6 70630-17-0 methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate Metalaxyl-M C15H21NO4 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is identical to the substance Metalaxyl-M 615-135-6 70630-17-0 methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate Metalaxyl-M C15H21NO4 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is identical to the substance Metalaxyl-M 615-135-6 70630-17-0 methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate Metalaxyl-M C15H21NO4 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is identical to the substance Metalaxyl-M 615-135-6 70630-17-0 methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate Metalaxyl-M C15H21NO4 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is identical to the substance Metalaxyl-M 615-135-6 70630-17-0 methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate Metalaxyl-M C15H21NO4 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is identical to the substance Metalaxyl-M 615-135-6 70630-17-0 methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate Metalaxyl-M C15H21NO4 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro Equivalent or similar to OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay) Yes Acceptable Saccharomyces cerevisiae (as organism) D7 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is identical to the substance Metalaxyl-M 615-135-6 70630-17-0 methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate Metalaxyl-M C15H21NO4 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro Equivalent or similar to OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay) Yes Acceptable Saccharomyces cerevisiae (as organism) D7 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is identical to the substance Metalaxyl-M 615-135-6 70630-17-0 methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate Metalaxyl-M C15H21NO4 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative no information RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is identical to the substance Metalaxyl-M 615-135-6 70630-17-0 methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate Metalaxyl-M C15H21NO4 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Negative no information RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is identical to the substance Metalaxyl-M 615-135-6 70630-17-0 methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate Metalaxyl-M C15H21NO4 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is identical to the substance Metalaxyl-M 615-135-6 70630-17-0 methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate Metalaxyl-M C15H21NO4 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Human (as organism) fibroblast Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is identical to the substance Metalaxyl-M 615-135-6 70630-17-0 methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate Metalaxyl-M C15H21NO4 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable Hamster (as animal) Chinese 12 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is identical to the substance Metalaxyl-M 615-135-6 70630-17-0 methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate Metalaxyl-M C15H21NO4 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Tif:MAGf(SPF) 10 Male/Female oral: gavage 16.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is identical to the substance Metalaxyl-M 615-135-6 70630-17-0 methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate Metalaxyl-M C15H21NO4 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Tif:MAGf(SPF) 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is identical to the substance Metalaxyl-M 615-135-6 70630-17-0 methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate Metalaxyl-M C15H21NO4 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Tif:MAGf(SPF) 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is identical to the substance Metalaxyl-M 615-135-6 70630-17-0 methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate Metalaxyl-M C15H21NO4 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) Yes Acceptable House mouse (as animal) NMRI 20 Male oral: unspecified 8.0000000000 week yes, concurrent no treatment not applicable Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Mandipropamid 374726-62-2 single chemical entity Component is identical to the substance Mandipropamid 374726-62-2 2-(4-chlorophenyl)-N-{2-[3-methoxy-4-(prop-2-yn-1-yloxy)phenyl]ethyl}-2-(prop-2-yn-1-yloxy)acetamide Mandipropamid C23H22ClNO4 Clc1ccc(cc1)C(OCC#C)C(=O)NCCc2ccc(OCC#C)c(OC)c2 InChI=1S/C23H22ClNO4/c1-4-14-28-20-11-6-17(16-21(20)27-3)12-13-25-23(26)22(29-15-5-2)18-7-9-19(24)10-8-18/h1-2,6-11,16,22H,12-15H2,3H3,(H,25,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Austria Mandipropamid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid 05Nov2012 2012 doi:10.2903/j.efsa.2012.2935
+Mandipropamid 374726-62-2 single chemical entity Component is identical to the substance Mandipropamid 374726-62-2 2-(4-chlorophenyl)-N-{2-[3-methoxy-4-(prop-2-yn-1-yloxy)phenyl]ethyl}-2-(prop-2-yn-1-yloxy)acetamide Mandipropamid C23H22ClNO4 Clc1ccc(cc1)C(OCC#C)C(=O)NCCc2ccc(OCC#C)c(OC)c2 InChI=1S/C23H22ClNO4/c1-4-14-28-20-11-6-17(16-21(20)27-3)12-13-25-23(26)22(29-15-5-2)18-7-9-19(24)10-8-18/h1-2,6-11,16,22H,12-15H2,3H3,(H,25,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle with Negative RMS: Austria Mandipropamid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid 05Nov2012 2012 doi:10.2903/j.efsa.2012.2935
+Mandipropamid 374726-62-2 single chemical entity Component is identical to the substance Mandipropamid 374726-62-2 2-(4-chlorophenyl)-N-{2-[3-methoxy-4-(prop-2-yn-1-yloxy)phenyl]ethyl}-2-(prop-2-yn-1-yloxy)acetamide Mandipropamid C23H22ClNO4 Clc1ccc(cc1)C(OCC#C)C(=O)NCCc2ccc(OCC#C)c(OC)c2 InChI=1S/C23H22ClNO4/c1-4-14-28-20-11-6-17(16-21(20)27-3)12-13-25-23(26)22(29-15-5-2)18-7-9-19(24)10-8-18/h1-2,6-11,16,22H,12-15H2,3H3,(H,25,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Austria Mandipropamid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid 05Nov2012 2012 doi:10.2903/j.efsa.2012.2935
+Mandipropamid 374726-62-2 single chemical entity Component is identical to the substance Mandipropamid 374726-62-2 2-(4-chlorophenyl)-N-{2-[3-methoxy-4-(prop-2-yn-1-yloxy)phenyl]ethyl}-2-(prop-2-yn-1-yloxy)acetamide Mandipropamid C23H22ClNO4 Clc1ccc(cc1)C(OCC#C)C(=O)NCCc2ccc(OCC#C)c(OC)c2 InChI=1S/C23H22ClNO4/c1-4-14-28-20-11-6-17(16-21(20)27-3)12-13-25-23(26)22(29-15-5-2)18-7-9-19(24)10-8-18/h1-2,6-11,16,22H,12-15H2,3H3,(H,25,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Austria Mandipropamid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid 05Nov2012 2012 doi:10.2903/j.efsa.2012.2935
+Mandipropamid 374726-62-2 single chemical entity Component is identical to the substance Mandipropamid 374726-62-2 2-(4-chlorophenyl)-N-{2-[3-methoxy-4-(prop-2-yn-1-yloxy)phenyl]ethyl}-2-(prop-2-yn-1-yloxy)acetamide Mandipropamid C23H22ClNO4 Clc1ccc(cc1)C(OCC#C)C(=O)NCCc2ccc(OCC#C)c(OC)c2 InChI=1S/C23H22ClNO4/c1-4-14-28-20-11-6-17(16-21(20)27-3)12-13-25-23(26)22(29-15-5-2)18-7-9-19(24)10-8-18/h1-2,6-11,16,22H,12-15H2,3H3,(H,25,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle without Negative RMS: Austria Mandipropamid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid 05Nov2012 2012 doi:10.2903/j.efsa.2012.2935
+Mandipropamid 374726-62-2 single chemical entity Component is identical to the substance Mandipropamid 374726-62-2 2-(4-chlorophenyl)-N-{2-[3-methoxy-4-(prop-2-yn-1-yloxy)phenyl]ethyl}-2-(prop-2-yn-1-yloxy)acetamide Mandipropamid C23H22ClNO4 Clc1ccc(cc1)C(OCC#C)C(=O)NCCc2ccc(OCC#C)c(OC)c2 InChI=1S/C23H22ClNO4/c1-4-14-28-20-11-6-17(16-21(20)27-3)12-13-25-23(26)22(29-15-5-2)18-7-9-19(24)10-8-18/h1-2,6-11,16,22H,12-15H2,3H3,(H,25,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Austria Mandipropamid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid 05Nov2012 2012 doi:10.2903/j.efsa.2012.2935
+Mandipropamid 374726-62-2 single chemical entity Component is identical to the substance Mandipropamid 374726-62-2 2-(4-chlorophenyl)-N-{2-[3-methoxy-4-(prop-2-yn-1-yloxy)phenyl]ethyl}-2-(prop-2-yn-1-yloxy)acetamide Mandipropamid C23H22ClNO4 Clc1ccc(cc1)C(OCC#C)C(=O)NCCc2ccc(OCC#C)c(OC)c2 InChI=1S/C23H22ClNO4/c1-4-14-28-20-11-6-17(16-21(20)27-3)12-13-25-23(26)22(29-15-5-2)18-7-9-19(24)10-8-18/h1-2,6-11,16,22H,12-15H2,3H3,(H,25,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Austria Mandipropamid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid 05Nov2012 2012 doi:10.2903/j.efsa.2012.2935
+Mandipropamid 374726-62-2 single chemical entity Component is identical to the substance Mandipropamid 374726-62-2 2-(4-chlorophenyl)-N-{2-[3-methoxy-4-(prop-2-yn-1-yloxy)phenyl]ethyl}-2-(prop-2-yn-1-yloxy)acetamide Mandipropamid C23H22ClNO4 Clc1ccc(cc1)C(OCC#C)C(=O)NCCc2ccc(OCC#C)c(OC)c2 InChI=1S/C23H22ClNO4/c1-4-14-28-20-11-6-17(16-21(20)27-3)12-13-25-23(26)22(29-15-5-2)18-7-9-19(24)10-8-18/h1-2,6-11,16,22H,12-15H2,3H3,(H,25,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Austria Mandipropamid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid 05Nov2012 2012 doi:10.2903/j.efsa.2012.2935
+Mandipropamid 374726-62-2 single chemical entity Component is identical to the substance Mandipropamid 374726-62-2 2-(4-chlorophenyl)-N-{2-[3-methoxy-4-(prop-2-yn-1-yloxy)phenyl]ethyl}-2-(prop-2-yn-1-yloxy)acetamide Mandipropamid C23H22ClNO4 Clc1ccc(cc1)C(OCC#C)C(=O)NCCc2ccc(OCC#C)c(OC)c2 InChI=1S/C23H22ClNO4/c1-4-14-28-20-11-6-17(16-21(20)27-3)12-13-25-23(26)22(29-15-5-2)18-7-9-19(24)10-8-18/h1-2,6-11,16,22H,12-15H2,3H3,(H,25,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Austria Mandipropamid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid 05Nov2012 2012 doi:10.2903/j.efsa.2012.2935
+Mandipropamid 374726-62-2 single chemical entity Component is identical to the substance Mandipropamid 374726-62-2 2-(4-chlorophenyl)-N-{2-[3-methoxy-4-(prop-2-yn-1-yloxy)phenyl]ethyl}-2-(prop-2-yn-1-yloxy)acetamide Mandipropamid C23H22ClNO4 Clc1ccc(cc1)C(OCC#C)C(=O)NCCc2ccc(OCC#C)c(OC)c2 InChI=1S/C23H22ClNO4/c1-4-14-28-20-11-6-17(16-21(20)27-3)12-13-25-23(26)22(29-15-5-2)18-7-9-19(24)10-8-18/h1-2,6-11,16,22H,12-15H2,3H3,(H,25,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Austria Mandipropamid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid 05Nov2012 2012 doi:10.2903/j.efsa.2012.2935
+Mandipropamid 374726-62-2 single chemical entity Component is identical to the substance Mandipropamid 374726-62-2 2-(4-chlorophenyl)-N-{2-[3-methoxy-4-(prop-2-yn-1-yloxy)phenyl]ethyl}-2-(prop-2-yn-1-yloxy)acetamide Mandipropamid C23H22ClNO4 Clc1ccc(cc1)C(OCC#C)C(=O)NCCc2ccc(OCC#C)c(OC)c2 InChI=1S/C23H22ClNO4/c1-4-14-28-20-11-6-17(16-21(20)27-3)12-13-25-23(26)22(29-15-5-2)18-7-9-19(24)10-8-18/h1-2,6-11,16,22H,12-15H2,3H3,(H,25,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Austria Mandipropamid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid 05Nov2012 2012 doi:10.2903/j.efsa.2012.2935
+Mandipropamid 374726-62-2 single chemical entity Component is identical to the substance Mandipropamid 374726-62-2 2-(4-chlorophenyl)-N-{2-[3-methoxy-4-(prop-2-yn-1-yloxy)phenyl]ethyl}-2-(prop-2-yn-1-yloxy)acetamide Mandipropamid C23H22ClNO4 Clc1ccc(cc1)C(OCC#C)C(=O)NCCc2ccc(OCC#C)c(OC)c2 InChI=1S/C23H22ClNO4/c1-4-14-28-20-11-6-17(16-21(20)27-3)12-13-25-23(26)22(29-15-5-2)18-7-9-19(24)10-8-18/h1-2,6-11,16,22H,12-15H2,3H3,(H,25,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Austria Mandipropamid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid 05Nov2012 2012 doi:10.2903/j.efsa.2012.2935
+Mandipropamid 374726-62-2 single chemical entity Component is identical to the substance Mandipropamid 374726-62-2 2-(4-chlorophenyl)-N-{2-[3-methoxy-4-(prop-2-yn-1-yloxy)phenyl]ethyl}-2-(prop-2-yn-1-yloxy)acetamide Mandipropamid C23H22ClNO4 Clc1ccc(cc1)C(OCC#C)C(=O)NCCc2ccc(OCC#C)c(OC)c2 InChI=1S/C23H22ClNO4/c1-4-14-28-20-11-6-17(16-21(20)27-3)12-13-25-23(26)22(29-15-5-2)18-7-9-19(24)10-8-18/h1-2,6-11,16,22H,12-15H2,3H3,(H,25,26) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Austria Mandipropamid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid 05Nov2012 2012 doi:10.2903/j.efsa.2012.2935
+Mandipropamid 374726-62-2 single chemical entity Component is identical to the substance Mandipropamid 374726-62-2 2-(4-chlorophenyl)-N-{2-[3-methoxy-4-(prop-2-yn-1-yloxy)phenyl]ethyl}-2-(prop-2-yn-1-yloxy)acetamide Mandipropamid C23H22ClNO4 Clc1ccc(cc1)C(OCC#C)C(=O)NCCc2ccc(OCC#C)c(OC)c2 InChI=1S/C23H22ClNO4/c1-4-14-28-20-11-6-17(16-21(20)27-3)12-13-25-23(26)22(29-15-5-2)18-7-9-19(24)10-8-18/h1-2,6-11,16,22H,12-15H2,3H3,(H,25,26) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Austria Mandipropamid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid 05Nov2012 2012 doi:10.2903/j.efsa.2012.2935
+Mandipropamid 374726-62-2 single chemical entity Component is identical to the substance Mandipropamid 374726-62-2 2-(4-chlorophenyl)-N-{2-[3-methoxy-4-(prop-2-yn-1-yloxy)phenyl]ethyl}-2-(prop-2-yn-1-yloxy)acetamide Mandipropamid C23H22ClNO4 Clc1ccc(cc1)C(OCC#C)C(=O)NCCc2ccc(OCC#C)c(OC)c2 InChI=1S/C23H22ClNO4/c1-4-14-28-20-11-6-17(16-21(20)27-3)12-13-25-23(26)22(29-15-5-2)18-7-9-19(24)10-8-18/h1-2,6-11,16,22H,12-15H2,3H3,(H,25,26) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative small colonies RMS: Austria Mandipropamid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid 05Nov2012 2012 doi:10.2903/j.efsa.2012.2935
+Mandipropamid 374726-62-2 single chemical entity Component is identical to the substance Mandipropamid 374726-62-2 2-(4-chlorophenyl)-N-{2-[3-methoxy-4-(prop-2-yn-1-yloxy)phenyl]ethyl}-2-(prop-2-yn-1-yloxy)acetamide Mandipropamid C23H22ClNO4 Clc1ccc(cc1)C(OCC#C)C(=O)NCCc2ccc(OCC#C)c(OC)c2 InChI=1S/C23H22ClNO4/c1-4-14-28-20-11-6-17(16-21(20)27-3)12-13-25-23(26)22(29-15-5-2)18-7-9-19(24)10-8-18/h1-2,6-11,16,22H,12-15H2,3H3,(H,25,26) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative large colonies RMS: Austria Mandipropamid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid 05Nov2012 2012 doi:10.2903/j.efsa.2012.2935
+Mandipropamid 374726-62-2 single chemical entity Component is identical to the substance Mandipropamid 374726-62-2 2-(4-chlorophenyl)-N-{2-[3-methoxy-4-(prop-2-yn-1-yloxy)phenyl]ethyl}-2-(prop-2-yn-1-yloxy)acetamide Mandipropamid C23H22ClNO4 Clc1ccc(cc1)C(OCC#C)C(=O)NCCc2ccc(OCC#C)c(OC)c2 InChI=1S/C23H22ClNO4/c1-4-14-28-20-11-6-17(16-21(20)27-3)12-13-25-23(26)22(29-15-5-2)18-7-9-19(24)10-8-18/h1-2,6-11,16,22H,12-15H2,3H3,(H,25,26) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative large colonies RMS: Austria Mandipropamid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid 05Nov2012 2012 doi:10.2903/j.efsa.2012.2935
+Mandipropamid 374726-62-2 single chemical entity Component is identical to the substance Mandipropamid 374726-62-2 2-(4-chlorophenyl)-N-{2-[3-methoxy-4-(prop-2-yn-1-yloxy)phenyl]ethyl}-2-(prop-2-yn-1-yloxy)acetamide Mandipropamid C23H22ClNO4 Clc1ccc(cc1)C(OCC#C)C(=O)NCCc2ccc(OCC#C)c(OC)c2 InChI=1S/C23H22ClNO4/c1-4-14-28-20-11-6-17(16-21(20)27-3)12-13-25-23(26)22(29-15-5-2)18-7-9-19(24)10-8-18/h1-2,6-11,16,22H,12-15H2,3H3,(H,25,26) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative small colonies RMS: Austria Mandipropamid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid 05Nov2012 2012 doi:10.2903/j.efsa.2012.2935
+Mandipropamid 374726-62-2 single chemical entity Component is identical to the substance Mandipropamid 374726-62-2 2-(4-chlorophenyl)-N-{2-[3-methoxy-4-(prop-2-yn-1-yloxy)phenyl]ethyl}-2-(prop-2-yn-1-yloxy)acetamide Mandipropamid C23H22ClNO4 Clc1ccc(cc1)C(OCC#C)C(=O)NCCc2ccc(OCC#C)c(OC)c2 InChI=1S/C23H22ClNO4/c1-4-14-28-20-11-6-17(16-21(20)27-3)12-13-25-23(26)22(29-15-5-2)18-7-9-19(24)10-8-18/h1-2,6-11,16,22H,12-15H2,3H3,(H,25,26) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable Rat (as animal) Wistar 10 Male oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Austria Mandipropamid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid 05Nov2012 2012 doi:10.2903/j.efsa.2012.2935
+Mandipropamid 374726-62-2 single chemical entity Component is identical to the substance Mandipropamid 374726-62-2 2-(4-chlorophenyl)-N-{2-[3-methoxy-4-(prop-2-yn-1-yloxy)phenyl]ethyl}-2-(prop-2-yn-1-yloxy)acetamide Mandipropamid C23H22ClNO4 Clc1ccc(cc1)C(OCC#C)C(=O)NCCc2ccc(OCC#C)c(OC)c2 InChI=1S/C23H22ClNO4/c1-4-14-28-20-11-6-17(16-21(20)27-3)12-13-25-23(26)22(29-15-5-2)18-7-9-19(24)10-8-18/h1-2,6-11,16,22H,12-15H2,3H3,(H,25,26) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable Rat (as animal) Wistar 10 Male oral: unspecified 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Austria Mandipropamid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid 05Nov2012 2012 doi:10.2903/j.efsa.2012.2935
+Mandipropamid 374726-62-2 single chemical entity Component is identical to the substance Mandipropamid 374726-62-2 2-(4-chlorophenyl)-N-{2-[3-methoxy-4-(prop-2-yn-1-yloxy)phenyl]ethyl}-2-(prop-2-yn-1-yloxy)acetamide Mandipropamid C23H22ClNO4 Clc1ccc(cc1)C(OCC#C)C(=O)NCCc2ccc(OCC#C)c(OC)c2 InChI=1S/C23H22ClNO4/c1-4-14-28-20-11-6-17(16-21(20)27-3)12-13-25-23(26)22(29-15-5-2)18-7-9-19(24)10-8-18/h1-2,6-11,16,22H,12-15H2,3H3,(H,25,26) organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Wistar 3 Male oral: unspecified 2.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Austria Mandipropamid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid 05Nov2012 2012 doi:10.2903/j.efsa.2012.2935
+Mandipropamid 374726-62-2 single chemical entity Component is identical to the substance Mandipropamid 374726-62-2 2-(4-chlorophenyl)-N-{2-[3-methoxy-4-(prop-2-yn-1-yloxy)phenyl]ethyl}-2-(prop-2-yn-1-yloxy)acetamide Mandipropamid C23H22ClNO4 Clc1ccc(cc1)C(OCC#C)C(=O)NCCc2ccc(OCC#C)c(OC)c2 InChI=1S/C23H22ClNO4/c1-4-14-28-20-11-6-17(16-21(20)27-3)12-13-25-23(26)22(29-15-5-2)18-7-9-19(24)10-8-18/h1-2,6-11,16,22H,12-15H2,3H3,(H,25,26) organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Wistar 3 Male oral: unspecified 16.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Austria Mandipropamid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid 05Nov2012 2012 doi:10.2903/j.efsa.2012.2935
+Mandipropamid 374726-62-2 single chemical entity Component is a metabolite of the substance (4-Chloro-phenyl)-prop-2-ynyloxy-acetic acid 3-{[(4-chlorophenyl)(prop-2-yn-1-yloxy)acetyl]amino}propanoic acid Not in list C14H14ClNO4 Clc1ccc(cc1)C(OCC#C)C(=O)NCCC(=O)O InChI=1/C14H14ClNO4/c1-2-9-20-13(10-3-5-11(15)6-4-10)14(19)16-8-7-12(17)18/h1,3-6,13H,7-9H2,(H,16,19)(H,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Austria Mandipropamid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid 05Nov2012 2012 doi:10.2903/j.efsa.2012.2935
+Mandipropamid 374726-62-2 single chemical entity Component is a metabolite of the substance (4-Chloro-phenyl)-prop-2-ynyloxy-acetic acid 3-{[(4-chlorophenyl)(prop-2-yn-1-yloxy)acetyl]amino}propanoic acid Not in list C14H14ClNO4 Clc1ccc(cc1)C(OCC#C)C(=O)NCCC(=O)O InChI=1/C14H14ClNO4/c1-2-9-20-13(10-3-5-11(15)6-4-10)14(19)16-8-7-12(17)18/h1,3-6,13H,7-9H2,(H,16,19)(H,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Austria Mandipropamid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid 05Nov2012 2012 doi:10.2903/j.efsa.2012.2935
+Mandipropamid 374726-62-2 single chemical entity Component is a metabolite of the substance (4-Chloro-phenyl)-prop-2-ynyloxy-acetic acid 3-{[(4-chlorophenyl)(prop-2-yn-1-yloxy)acetyl]amino}propanoic acid Not in list C14H14ClNO4 Clc1ccc(cc1)C(OCC#C)C(=O)NCCC(=O)O InChI=1/C14H14ClNO4/c1-2-9-20-13(10-3-5-11(15)6-4-10)14(19)16-8-7-12(17)18/h1,3-6,13H,7-9H2,(H,16,19)(H,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle without Negative RMS: Austria Mandipropamid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid 05Nov2012 2012 doi:10.2903/j.efsa.2012.2935
+Mandipropamid 374726-62-2 single chemical entity Component is a metabolite of the substance (4-Chloro-phenyl)-prop-2-ynyloxy-acetic acid 3-{[(4-chlorophenyl)(prop-2-yn-1-yloxy)acetyl]amino}propanoic acid Not in list C14H14ClNO4 Clc1ccc(cc1)C(OCC#C)C(=O)NCCC(=O)O InChI=1/C14H14ClNO4/c1-2-9-20-13(10-3-5-11(15)6-4-10)14(19)16-8-7-12(17)18/h1,3-6,13H,7-9H2,(H,16,19)(H,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Austria Mandipropamid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid 05Nov2012 2012 doi:10.2903/j.efsa.2012.2935
+Mandipropamid 374726-62-2 single chemical entity Component is a metabolite of the substance (4-Chloro-phenyl)-prop-2-ynyloxy-acetic acid 3-{[(4-chlorophenyl)(prop-2-yn-1-yloxy)acetyl]amino}propanoic acid Not in list C14H14ClNO4 Clc1ccc(cc1)C(OCC#C)C(=O)NCCC(=O)O InChI=1/C14H14ClNO4/c1-2-9-20-13(10-3-5-11(15)6-4-10)14(19)16-8-7-12(17)18/h1,3-6,13H,7-9H2,(H,16,19)(H,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle with Negative RMS: Austria Mandipropamid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid 05Nov2012 2012 doi:10.2903/j.efsa.2012.2935
+Mandipropamid 374726-62-2 single chemical entity Component is a metabolite of the substance (4-Chloro-phenyl)-prop-2-ynyloxy-acetic acid 3-{[(4-chlorophenyl)(prop-2-yn-1-yloxy)acetyl]amino}propanoic acid Not in list C14H14ClNO4 Clc1ccc(cc1)C(OCC#C)C(=O)NCCC(=O)O InChI=1/C14H14ClNO4/c1-2-9-20-13(10-3-5-11(15)6-4-10)14(19)16-8-7-12(17)18/h1,3-6,13H,7-9H2,(H,16,19)(H,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Austria Mandipropamid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid 05Nov2012 2012 doi:10.2903/j.efsa.2012.2935
+Mandipropamid 374726-62-2 single chemical entity Component is a metabolite of the substance (4-Chloro-phenyl)-prop-2-ynyloxy-acetic acid 3-{[(4-chlorophenyl)(prop-2-yn-1-yloxy)acetyl]amino}propanoic acid Not in list C14H14ClNO4 Clc1ccc(cc1)C(OCC#C)C(=O)NCCC(=O)O InChI=1/C14H14ClNO4/c1-2-9-20-13(10-3-5-11(15)6-4-10)14(19)16-8-7-12(17)18/h1,3-6,13H,7-9H2,(H,16,19)(H,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Austria Mandipropamid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid 05Nov2012 2012 doi:10.2903/j.efsa.2012.2935
+Mandipropamid 374726-62-2 single chemical entity Component is a metabolite of the substance (4-Chloro-phenyl)-prop-2-ynyloxy-acetic acid 3-{[(4-chlorophenyl)(prop-2-yn-1-yloxy)acetyl]amino}propanoic acid Not in list C14H14ClNO4 Clc1ccc(cc1)C(OCC#C)C(=O)NCCC(=O)O InChI=1/C14H14ClNO4/c1-2-9-20-13(10-3-5-11(15)6-4-10)14(19)16-8-7-12(17)18/h1,3-6,13H,7-9H2,(H,16,19)(H,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Austria Mandipropamid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid 05Nov2012 2012 doi:10.2903/j.efsa.2012.2935
+Mandipropamid 374726-62-2 single chemical entity Component is a metabolite of the substance (4-Chloro-phenyl)-prop-2-ynyloxy-acetic acid 3-{[(4-chlorophenyl)(prop-2-yn-1-yloxy)acetyl]amino}propanoic acid Not in list C14H14ClNO4 Clc1ccc(cc1)C(OCC#C)C(=O)NCCC(=O)O InChI=1/C14H14ClNO4/c1-2-9-20-13(10-3-5-11(15)6-4-10)14(19)16-8-7-12(17)18/h1,3-6,13H,7-9H2,(H,16,19)(H,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Austria Mandipropamid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid 05Nov2012 2012 doi:10.2903/j.efsa.2012.2935
+Mandipropamid 374726-62-2 single chemical entity Component is a metabolite of the substance (4-Chloro-phenyl)-prop-2-ynyloxy-acetic acid 3-{[(4-chlorophenyl)(prop-2-yn-1-yloxy)acetyl]amino}propanoic acid Not in list C14H14ClNO4 Clc1ccc(cc1)C(OCC#C)C(=O)NCCC(=O)O InChI=1/C14H14ClNO4/c1-2-9-20-13(10-3-5-11(15)6-4-10)14(19)16-8-7-12(17)18/h1,3-6,13H,7-9H2,(H,16,19)(H,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle with Negative RMS: Austria Mandipropamid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid 05Nov2012 2012 doi:10.2903/j.efsa.2012.2935
+Mandipropamid 374726-62-2 single chemical entity Component is a metabolite of the substance (4-Chloro-phenyl)-prop-2-ynyloxy-acetic acid 3-{[(4-chlorophenyl)(prop-2-yn-1-yloxy)acetyl]amino}propanoic acid Not in list C14H14ClNO4 Clc1ccc(cc1)C(OCC#C)C(=O)NCCC(=O)O InChI=1/C14H14ClNO4/c1-2-9-20-13(10-3-5-11(15)6-4-10)14(19)16-8-7-12(17)18/h1,3-6,13H,7-9H2,(H,16,19)(H,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle without Negative RMS: Austria Mandipropamid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid 05Nov2012 2012 doi:10.2903/j.efsa.2012.2935
+Mandipropamid 374726-62-2 single chemical entity Component is a metabolite of the substance (4-Chloro-phenyl)-prop-2-ynyloxy-acetic acid 3-{[(4-chlorophenyl)(prop-2-yn-1-yloxy)acetyl]amino}propanoic acid Not in list C14H14ClNO4 Clc1ccc(cc1)C(OCC#C)C(=O)NCCC(=O)O InChI=1/C14H14ClNO4/c1-2-9-20-13(10-3-5-11(15)6-4-10)14(19)16-8-7-12(17)18/h1,3-6,13H,7-9H2,(H,16,19)(H,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Austria Mandipropamid 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid 05Nov2012 2012 doi:10.2903/j.efsa.2012.2935
+Lufenuron 103055-07-8 single chemical entity Component is identical to the substance Lufenuron 103055-07-8 N-{[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]carbamoyl}-2,6-difluorobenzamide Lufenuron C17H8Cl2F8N2O3 O=C(NC(NC2=C(Cl)C=C(OC(F)(F)C(F)C(F)(F)F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F InChI=1S/C17H8Cl2F8N2O3/c18-6-5-11(32-17(26,27)14(22)16(23,24)25)7(19)4-10(6)28-15(31)29-13(30)12-8(20)2-1-3-9(12)21/h1-5,14H,(H2,28,29,30,31) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Portugal Lufenuron 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance lufenuron 22Jun2009 2009 doi:10.2903/j.efsa.2009.189r
+Lufenuron 103055-07-8 single chemical entity Component is identical to the substance Lufenuron 103055-07-8 N-{[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]carbamoyl}-2,6-difluorobenzamide Lufenuron C17H8Cl2F8N2O3 O=C(NC(NC2=C(Cl)C=C(OC(F)(F)C(F)C(F)(F)F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F InChI=1S/C17H8Cl2F8N2O3/c18-6-5-11(32-17(26,27)14(22)16(23,24)25)7(19)4-10(6)28-15(31)29-13(30)12-8(20)2-1-3-9(12)21/h1-5,14H,(H2,28,29,30,31) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Portugal Lufenuron 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance lufenuron 22Jun2009 2009 doi:10.2903/j.efsa.2009.189r
+Lufenuron 103055-07-8 single chemical entity Component is identical to the substance Lufenuron 103055-07-8 N-{[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]carbamoyl}-2,6-difluorobenzamide Lufenuron C17H8Cl2F8N2O3 O=C(NC(NC2=C(Cl)C=C(OC(F)(F)C(F)C(F)(F)F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F InChI=1S/C17H8Cl2F8N2O3/c18-6-5-11(32-17(26,27)14(22)16(23,24)25)7(19)4-10(6)28-15(31)29-13(30)12-8(20)2-1-3-9(12)21/h1-5,14H,(H2,28,29,30,31) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Portugal Lufenuron 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance lufenuron 22Jun2009 2009 doi:10.2903/j.efsa.2009.189r
+Lufenuron 103055-07-8 single chemical entity Component is identical to the substance Lufenuron 103055-07-8 N-{[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]carbamoyl}-2,6-difluorobenzamide Lufenuron C17H8Cl2F8N2O3 O=C(NC(NC2=C(Cl)C=C(OC(F)(F)C(F)C(F)(F)F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F InChI=1S/C17H8Cl2F8N2O3/c18-6-5-11(32-17(26,27)14(22)16(23,24)25)7(19)4-10(6)28-15(31)29-13(30)12-8(20)2-1-3-9(12)21/h1-5,14H,(H2,28,29,30,31) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Portugal Lufenuron 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance lufenuron 22Jun2009 2009 doi:10.2903/j.efsa.2009.189r
+Lufenuron 103055-07-8 single chemical entity Component is identical to the substance Lufenuron 103055-07-8 N-{[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]carbamoyl}-2,6-difluorobenzamide Lufenuron C17H8Cl2F8N2O3 O=C(NC(NC2=C(Cl)C=C(OC(F)(F)C(F)C(F)(F)F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F InChI=1S/C17H8Cl2F8N2O3/c18-6-5-11(32-17(26,27)14(22)16(23,24)25)7(19)4-10(6)28-15(31)29-13(30)12-8(20)2-1-3-9(12)21/h1-5,14H,(H2,28,29,30,31) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Portugal Lufenuron 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance lufenuron 22Jun2009 2009 doi:10.2903/j.efsa.2009.189r
+Lufenuron 103055-07-8 single chemical entity Component is identical to the substance Lufenuron 103055-07-8 N-{[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]carbamoyl}-2,6-difluorobenzamide Lufenuron C17H8Cl2F8N2O3 O=C(NC(NC2=C(Cl)C=C(OC(F)(F)C(F)C(F)(F)F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F InChI=1S/C17H8Cl2F8N2O3/c18-6-5-11(32-17(26,27)14(22)16(23,24)25)7(19)4-10(6)28-15(31)29-13(30)12-8(20)2-1-3-9(12)21/h1-5,14H,(H2,28,29,30,31) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Portugal Lufenuron 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance lufenuron 22Jun2009 2009 doi:10.2903/j.efsa.2009.189r
+Lufenuron 103055-07-8 single chemical entity Component is identical to the substance Lufenuron 103055-07-8 N-{[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]carbamoyl}-2,6-difluorobenzamide Lufenuron C17H8Cl2F8N2O3 O=C(NC(NC2=C(Cl)C=C(OC(F)(F)C(F)C(F)(F)F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F InChI=1S/C17H8Cl2F8N2O3/c18-6-5-11(32-17(26,27)14(22)16(23,24)25)7(19)4-10(6)28-15(31)29-13(30)12-8(20)2-1-3-9(12)21/h1-5,14H,(H2,28,29,30,31) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Portugal Lufenuron 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance lufenuron 22Jun2009 2009 doi:10.2903/j.efsa.2009.189r
+Lufenuron 103055-07-8 single chemical entity Component is identical to the substance Lufenuron 103055-07-8 N-{[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]carbamoyl}-2,6-difluorobenzamide Lufenuron C17H8Cl2F8N2O3 O=C(NC(NC2=C(Cl)C=C(OC(F)(F)C(F)C(F)(F)F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F InChI=1S/C17H8Cl2F8N2O3/c18-6-5-11(32-17(26,27)14(22)16(23,24)25)7(19)4-10(6)28-15(31)29-13(30)12-8(20)2-1-3-9(12)21/h1-5,14H,(H2,28,29,30,31) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Portugal Lufenuron 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance lufenuron 22Jun2009 2009 doi:10.2903/j.efsa.2009.189r
+Lufenuron 103055-07-8 single chemical entity Component is identical to the substance Lufenuron 103055-07-8 N-{[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]carbamoyl}-2,6-difluorobenzamide Lufenuron C17H8Cl2F8N2O3 O=C(NC(NC2=C(Cl)C=C(OC(F)(F)C(F)C(F)(F)F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F InChI=1S/C17H8Cl2F8N2O3/c18-6-5-11(32-17(26,27)14(22)16(23,24)25)7(19)4-10(6)28-15(31)29-13(30)12-8(20)2-1-3-9(12)21/h1-5,14H,(H2,28,29,30,31) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Portugal Lufenuron 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance lufenuron 22Jun2009 2009 doi:10.2903/j.efsa.2009.189r
+Lufenuron 103055-07-8 single chemical entity Component is identical to the substance Lufenuron 103055-07-8 N-{[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]carbamoyl}-2,6-difluorobenzamide Lufenuron C17H8Cl2F8N2O3 O=C(NC(NC2=C(Cl)C=C(OC(F)(F)C(F)C(F)(F)F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F InChI=1S/C17H8Cl2F8N2O3/c18-6-5-11(32-17(26,27)14(22)16(23,24)25)7(19)4-10(6)28-15(31)29-13(30)12-8(20)2-1-3-9(12)21/h1-5,14H,(H2,28,29,30,31) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Portugal Lufenuron 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance lufenuron 22Jun2009 2009 doi:10.2903/j.efsa.2009.189r
+Lufenuron 103055-07-8 single chemical entity Component is identical to the substance Lufenuron 103055-07-8 N-{[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]carbamoyl}-2,6-difluorobenzamide Lufenuron C17H8Cl2F8N2O3 O=C(NC(NC2=C(Cl)C=C(OC(F)(F)C(F)C(F)(F)F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F InChI=1S/C17H8Cl2F8N2O3/c18-6-5-11(32-17(26,27)14(22)16(23,24)25)7(19)4-10(6)28-15(31)29-13(30)12-8(20)2-1-3-9(12)21/h1-5,14H,(H2,28,29,30,31) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: Portugal Lufenuron 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance lufenuron 22Jun2009 2009 doi:10.2903/j.efsa.2009.189r
+Lufenuron 103055-07-8 single chemical entity Component is identical to the substance Lufenuron 103055-07-8 N-{[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]carbamoyl}-2,6-difluorobenzamide Lufenuron C17H8Cl2F8N2O3 O=C(NC(NC2=C(Cl)C=C(OC(F)(F)C(F)C(F)(F)F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F InChI=1S/C17H8Cl2F8N2O3/c18-6-5-11(32-17(26,27)14(22)16(23,24)25)7(19)4-10(6)28-15(31)29-13(30)12-8(20)2-1-3-9(12)21/h1-5,14H,(H2,28,29,30,31) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: Portugal Lufenuron 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance lufenuron 22Jun2009 2009 doi:10.2903/j.efsa.2009.189r
+Lufenuron 103055-07-8 single chemical entity Component is identical to the substance Lufenuron 103055-07-8 N-{[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]carbamoyl}-2,6-difluorobenzamide Lufenuron C17H8Cl2F8N2O3 O=C(NC(NC2=C(Cl)C=C(OC(F)(F)C(F)C(F)(F)F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F InChI=1S/C17H8Cl2F8N2O3/c18-6-5-11(32-17(26,27)14(22)16(23,24)25)7(19)4-10(6)28-15(31)29-13(30)12-8(20)2-1-3-9(12)21/h1-5,14H,(H2,28,29,30,31) organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Portugal Lufenuron 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance lufenuron 22Jun2009 2009 doi:10.2903/j.efsa.2009.189r
+Lufenuron 103055-07-8 single chemical entity Component is identical to the substance Lufenuron 103055-07-8 N-{[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]carbamoyl}-2,6-difluorobenzamide Lufenuron C17H8Cl2F8N2O3 O=C(NC(NC2=C(Cl)C=C(OC(F)(F)C(F)C(F)(F)F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F InChI=1S/C17H8Cl2F8N2O3/c18-6-5-11(32-17(26,27)14(22)16(23,24)25)7(19)4-10(6)28-15(31)29-13(30)12-8(20)2-1-3-9(12)21/h1-5,14H,(H2,28,29,30,31) organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Human (as organism) fibroblast Not reported yes, concurrent vehicle without Negative RMS: Portugal Lufenuron 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance lufenuron 22Jun2009 2009 doi:10.2903/j.efsa.2009.189r
+Lufenuron 103055-07-8 single chemical entity Component is identical to the substance Lufenuron 103055-07-8 N-{[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]carbamoyl}-2,6-difluorobenzamide Lufenuron C17H8Cl2F8N2O3 O=C(NC(NC2=C(Cl)C=C(OC(F)(F)C(F)C(F)(F)F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F InChI=1S/C17H8Cl2F8N2O3/c18-6-5-11(32-17(26,27)14(22)16(23,24)25)7(19)4-10(6)28-15(31)29-13(30)12-8(20)2-1-3-9(12)21/h1-5,14H,(H2,28,29,30,31) organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Human (as organism) fibroblast Not reported yes, concurrent vehicle without Negative RMS: Portugal Lufenuron 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance lufenuron 22Jun2009 2009 doi:10.2903/j.efsa.2009.189r
+Lufenuron 103055-07-8 single chemical entity Component is identical to the substance Lufenuron 103055-07-8 N-{[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]carbamoyl}-2,6-difluorobenzamide Lufenuron C17H8Cl2F8N2O3 O=C(NC(NC2=C(Cl)C=C(OC(F)(F)C(F)C(F)(F)F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F InChI=1S/C17H8Cl2F8N2O3/c18-6-5-11(32-17(26,27)14(22)16(23,24)25)7(19)4-10(6)28-15(31)29-13(30)12-8(20)2-1-3-9(12)21/h1-5,14H,(H2,28,29,30,31) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 16 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Portugal Lufenuron 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance lufenuron 22Jun2009 2009 doi:10.2903/j.efsa.2009.189r
+Lufenuron 103055-07-8 single chemical entity Component is identical to the substance Lufenuron 103055-07-8 N-{[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]carbamoyl}-2,6-difluorobenzamide Lufenuron C17H8Cl2F8N2O3 O=C(NC(NC2=C(Cl)C=C(OC(F)(F)C(F)C(F)(F)F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F InChI=1S/C17H8Cl2F8N2O3/c18-6-5-11(32-17(26,27)14(22)16(23,24)25)7(19)4-10(6)28-15(31)29-13(30)12-8(20)2-1-3-9(12)21/h1-5,14H,(H2,28,29,30,31) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 16 Male/Female oral: gavage 16.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Portugal Lufenuron 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance lufenuron 22Jun2009 2009 doi:10.2903/j.efsa.2009.189r
+Lufenuron 103055-07-8 single chemical entity Component is identical to the substance Lufenuron 103055-07-8 N-{[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]carbamoyl}-2,6-difluorobenzamide Lufenuron C17H8Cl2F8N2O3 O=C(NC(NC2=C(Cl)C=C(OC(F)(F)C(F)C(F)(F)F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F InChI=1S/C17H8Cl2F8N2O3/c18-6-5-11(32-17(26,27)14(22)16(23,24)25)7(19)4-10(6)28-15(31)29-13(30)12-8(20)2-1-3-9(12)21/h1-5,14H,(H2,28,29,30,31) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 16 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Portugal Lufenuron 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance lufenuron 22Jun2009 2009 doi:10.2903/j.efsa.2009.189r
+Lufenuron 103055-07-8 single chemical entity Component is identical to the substance Lufenuron 103055-07-8 N-{[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]carbamoyl}-2,6-difluorobenzamide Lufenuron C17H8Cl2F8N2O3 O=C(NC(NC2=C(Cl)C=C(OC(F)(F)C(F)C(F)(F)F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F InChI=1S/C17H8Cl2F8N2O3/c18-6-5-11(32-17(26,27)14(22)16(23,24)25)7(19)4-10(6)28-15(31)29-13(30)12-8(20)2-1-3-9(12)21/h1-5,14H,(H2,28,29,30,31) organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo Equivalent or similar to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) Yes Acceptable Rat (as animal) Sprague-Dawley 4 Male oral: gavage 16.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Portugal Lufenuron 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance lufenuron 22Jun2009 2009 doi:10.2903/j.efsa.2009.189r
+Lufenuron 103055-07-8 single chemical entity Component is identical to the substance Lufenuron 103055-07-8 N-{[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]carbamoyl}-2,6-difluorobenzamide Lufenuron C17H8Cl2F8N2O3 O=C(NC(NC2=C(Cl)C=C(OC(F)(F)C(F)C(F)(F)F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F InChI=1S/C17H8Cl2F8N2O3/c18-6-5-11(32-17(26,27)14(22)16(23,24)25)7(19)4-10(6)28-15(31)29-13(30)12-8(20)2-1-3-9(12)21/h1-5,14H,(H2,28,29,30,31) organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Wistar 3 Male oral: gavage 16.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Portugal Lufenuron 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance lufenuron 22Jun2009 2009 doi:10.2903/j.efsa.2009.189r
+Lufenuron 103055-07-8 single chemical entity Component is identical to the substance Lufenuron 103055-07-8 N-{[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]carbamoyl}-2,6-difluorobenzamide Lufenuron C17H8Cl2F8N2O3 O=C(NC(NC2=C(Cl)C=C(OC(F)(F)C(F)C(F)(F)F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F InChI=1S/C17H8Cl2F8N2O3/c18-6-5-11(32-17(26,27)14(22)16(23,24)25)7(19)4-10(6)28-15(31)29-13(30)12-8(20)2-1-3-9(12)21/h1-5,14H,(H2,28,29,30,31) organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Wistar 3 Male oral: gavage 4.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Portugal Lufenuron 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance lufenuron 22Jun2009 2009 doi:10.2903/j.efsa.2009.189r
+Lufenuron 103055-07-8 single chemical entity Component is a metabolite of the substance 2,5-Dichloro-4-(1,1,2,3,3,3-hexafluoro-propoxy)-phenylamine 2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)aniline Not in list C9H5Cl2F6NO Clc1cc(N)c(Cl)cc1OC(F)(F)C(F)C(F)(F)F InChI=1S/C9H5Cl2F6NO/c10-3-2-6(4(11)1-5(3)18)19-9(16,17)7(12)8(13,14)15/h1-2,7H,18H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Portugal Lufenuron 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance lufenuron 22Jun2009 2009 doi:10.2903/j.efsa.2009.189r
+Lufenuron 103055-07-8 single chemical entity Component is a metabolite of the substance 2,5-Dichloro-4-(1,1,2,3,3,3-hexafluoro-propoxy)-phenylamine 2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)aniline Not in list C9H5Cl2F6NO Clc1cc(N)c(Cl)cc1OC(F)(F)C(F)C(F)(F)F InChI=1S/C9H5Cl2F6NO/c10-3-2-6(4(11)1-5(3)18)19-9(16,17)7(12)8(13,14)15/h1-2,7H,18H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Portugal Lufenuron 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance lufenuron 22Jun2009 2009 doi:10.2903/j.efsa.2009.189r
+Lufenuron 103055-07-8 single chemical entity Component is a metabolite of the substance 2,5-Dichloro-4-(1,1,2,3,3,3-hexafluoro-propoxy)-phenylamine 2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)aniline Not in list C9H5Cl2F6NO Clc1cc(N)c(Cl)cc1OC(F)(F)C(F)C(F)(F)F InChI=1S/C9H5Cl2F6NO/c10-3-2-6(4(11)1-5(3)18)19-9(16,17)7(12)8(13,14)15/h1-2,7H,18H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Portugal Lufenuron 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance lufenuron 22Jun2009 2009 doi:10.2903/j.efsa.2009.189r
+Lufenuron 103055-07-8 single chemical entity Component is a metabolite of the substance 2,5-Dichloro-4-(1,1,2,3,3,3-hexafluoro-propoxy)-phenylamine 2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)aniline Not in list C9H5Cl2F6NO Clc1cc(N)c(Cl)cc1OC(F)(F)C(F)C(F)(F)F InChI=1S/C9H5Cl2F6NO/c10-3-2-6(4(11)1-5(3)18)19-9(16,17)7(12)8(13,14)15/h1-2,7H,18H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Portugal Lufenuron 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance lufenuron 22Jun2009 2009 doi:10.2903/j.efsa.2009.189r
+Lufenuron 103055-07-8 single chemical entity Component is a metabolite of the substance 2,5-Dichloro-4-(1,1,2,3,3,3-hexafluoro-propoxy)-phenylamine 2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)aniline Not in list C9H5Cl2F6NO Clc1cc(N)c(Cl)cc1OC(F)(F)C(F)C(F)(F)F InChI=1S/C9H5Cl2F6NO/c10-3-2-6(4(11)1-5(3)18)19-9(16,17)7(12)8(13,14)15/h1-2,7H,18H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Portugal Lufenuron 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance lufenuron 22Jun2009 2009 doi:10.2903/j.efsa.2009.189r
+Lufenuron 103055-07-8 single chemical entity Component is a metabolite of the substance 2,5-Dichloro-4-(1,1,2,3,3,3-hexafluoro-propoxy)-phenylamine 2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)aniline Not in list C9H5Cl2F6NO Clc1cc(N)c(Cl)cc1OC(F)(F)C(F)C(F)(F)F InChI=1S/C9H5Cl2F6NO/c10-3-2-6(4(11)1-5(3)18)19-9(16,17)7(12)8(13,14)15/h1-2,7H,18H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Portugal Lufenuron 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance lufenuron 22Jun2009 2009 doi:10.2903/j.efsa.2009.189r
+Lufenuron 103055-07-8 single chemical entity Component is a metabolite of the substance 2,5-Dichloro-4-(1,1,2,3,3,3-hexafluoro-propoxy)-phenylamine 2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)aniline Not in list C9H5Cl2F6NO Clc1cc(N)c(Cl)cc1OC(F)(F)C(F)C(F)(F)F InChI=1S/C9H5Cl2F6NO/c10-3-2-6(4(11)1-5(3)18)19-9(16,17)7(12)8(13,14)15/h1-2,7H,18H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Portugal Lufenuron 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance lufenuron 22Jun2009 2009 doi:10.2903/j.efsa.2009.189r
+Lufenuron 103055-07-8 single chemical entity Component is a metabolite of the substance 2,5-Dichloro-4-(1,1,2,3,3,3-hexafluoro-propoxy)-phenylamine 2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)aniline Not in list C9H5Cl2F6NO Clc1cc(N)c(Cl)cc1OC(F)(F)C(F)C(F)(F)F InChI=1S/C9H5Cl2F6NO/c10-3-2-6(4(11)1-5(3)18)19-9(16,17)7(12)8(13,14)15/h1-2,7H,18H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Portugal Lufenuron 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance lufenuron 22Jun2009 2009 doi:10.2903/j.efsa.2009.189r
+Lufenuron 103055-07-8 single chemical entity Component is a metabolite of the substance 2,5-Dichloro-4-(1,1,2,3,3,3-hexafluoro-propoxy)-phenylamine 2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)aniline Not in list C9H5Cl2F6NO Clc1cc(N)c(Cl)cc1OC(F)(F)C(F)C(F)(F)F InChI=1S/C9H5Cl2F6NO/c10-3-2-6(4(11)1-5(3)18)19-9(16,17)7(12)8(13,14)15/h1-2,7H,18H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Portugal Lufenuron 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance lufenuron 22Jun2009 2009 doi:10.2903/j.efsa.2009.189r
+Lufenuron 103055-07-8 single chemical entity Component is a metabolite of the substance 2,5-Dichloro-4-(1,1,2,3,3,3-hexafluoro-propoxy)-phenylamine 2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)aniline Not in list C9H5Cl2F6NO Clc1cc(N)c(Cl)cc1OC(F)(F)C(F)C(F)(F)F InChI=1S/C9H5Cl2F6NO/c10-3-2-6(4(11)1-5(3)18)19-9(16,17)7(12)8(13,14)15/h1-2,7H,18H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Portugal Lufenuron 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance lufenuron 22Jun2009 2009 doi:10.2903/j.efsa.2009.189r
+Metosulam 139528-85-1 single chemical entity Component is identical to the substance Metosulam 139528-85-1 N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide Metosulam C14H13Cl2N5O4S Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(cc(OC)n2n1)OC InChI=1S/C14H13Cl2N5O4S/c1-7-4-5-8(15)12(11(7)16)20-26(22,23)14-18-13-17-9(24-2)6-10(25-3)21(13)19-14/h4-6,20H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Metosulam 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam 05May2010 2010 doi:10.2903/j.efsa.2010.1592
+Metosulam 139528-85-1 single chemical entity Component is identical to the substance Metosulam 139528-85-1 N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide Metosulam C14H13Cl2N5O4S Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(cc(OC)n2n1)OC InChI=1S/C14H13Cl2N5O4S/c1-7-4-5-8(15)12(11(7)16)20-26(22,23)14-18-13-17-9(24-2)6-10(25-3)21(13)19-14/h4-6,20H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Metosulam 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam 05May2010 2010 doi:10.2903/j.efsa.2010.1592
+Metosulam 139528-85-1 single chemical entity Component is identical to the substance Metosulam 139528-85-1 N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide Metosulam C14H13Cl2N5O4S Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(cc(OC)n2n1)OC InChI=1S/C14H13Cl2N5O4S/c1-7-4-5-8(15)12(11(7)16)20-26(22,23)14-18-13-17-9(24-2)6-10(25-3)21(13)19-14/h4-6,20H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Metosulam 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam 05May2010 2010 doi:10.2903/j.efsa.2010.1592
+Metosulam 139528-85-1 single chemical entity Component is identical to the substance Metosulam 139528-85-1 N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide Metosulam C14H13Cl2N5O4S Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(cc(OC)n2n1)OC InChI=1S/C14H13Cl2N5O4S/c1-7-4-5-8(15)12(11(7)16)20-26(22,23)14-18-13-17-9(24-2)6-10(25-3)21(13)19-14/h4-6,20H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Metosulam 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam 05May2010 2010 doi:10.2903/j.efsa.2010.1592
+Metosulam 139528-85-1 single chemical entity Component is identical to the substance Metosulam 139528-85-1 N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide Metosulam C14H13Cl2N5O4S Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(cc(OC)n2n1)OC InChI=1S/C14H13Cl2N5O4S/c1-7-4-5-8(15)12(11(7)16)20-26(22,23)14-18-13-17-9(24-2)6-10(25-3)21(13)19-14/h4-6,20H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Metosulam 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam 05May2010 2010 doi:10.2903/j.efsa.2010.1592
+Metosulam 139528-85-1 single chemical entity Component is identical to the substance Metosulam 139528-85-1 N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide Metosulam C14H13Cl2N5O4S Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(cc(OC)n2n1)OC InChI=1S/C14H13Cl2N5O4S/c1-7-4-5-8(15)12(11(7)16)20-26(22,23)14-18-13-17-9(24-2)6-10(25-3)21(13)19-14/h4-6,20H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Metosulam 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam 05May2010 2010 doi:10.2903/j.efsa.2010.1592
+Metosulam 139528-85-1 single chemical entity Component is identical to the substance Metosulam 139528-85-1 N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide Metosulam C14H13Cl2N5O4S Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(cc(OC)n2n1)OC InChI=1S/C14H13Cl2N5O4S/c1-7-4-5-8(15)12(11(7)16)20-26(22,23)14-18-13-17-9(24-2)6-10(25-3)21(13)19-14/h4-6,20H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Metosulam 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam 05May2010 2010 doi:10.2903/j.efsa.2010.1592
+Metosulam 139528-85-1 single chemical entity Component is identical to the substance Metosulam 139528-85-1 N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide Metosulam C14H13Cl2N5O4S Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(cc(OC)n2n1)OC InChI=1S/C14H13Cl2N5O4S/c1-7-4-5-8(15)12(11(7)16)20-26(22,23)14-18-13-17-9(24-2)6-10(25-3)21(13)19-14/h4-6,20H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Metosulam 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam 05May2010 2010 doi:10.2903/j.efsa.2010.1592
+Metosulam 139528-85-1 single chemical entity Component is identical to the substance Metosulam 139528-85-1 N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide Metosulam C14H13Cl2N5O4S Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(cc(OC)n2n1)OC InChI=1S/C14H13Cl2N5O4S/c1-7-4-5-8(15)12(11(7)16)20-26(22,23)14-18-13-17-9(24-2)6-10(25-3)21(13)19-14/h4-6,20H,1-3H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: France Metosulam 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam 05May2010 2010 doi:10.2903/j.efsa.2010.1592
+Metosulam 139528-85-1 single chemical entity Component is identical to the substance Metosulam 139528-85-1 N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide Metosulam C14H13Cl2N5O4S Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(cc(OC)n2n1)OC InChI=1S/C14H13Cl2N5O4S/c1-7-4-5-8(15)12(11(7)16)20-26(22,23)14-18-13-17-9(24-2)6-10(25-3)21(13)19-14/h4-6,20H,1-3H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: France Metosulam 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam 05May2010 2010 doi:10.2903/j.efsa.2010.1592
+Metosulam 139528-85-1 single chemical entity Component is identical to the substance Metosulam 139528-85-1 N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide Metosulam C14H13Cl2N5O4S Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(cc(OC)n2n1)OC InChI=1S/C14H13Cl2N5O4S/c1-7-4-5-8(15)12(11(7)16)20-26(22,23)14-18-13-17-9(24-2)6-10(25-3)21(13)19-14/h4-6,20H,1-3H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: France Metosulam 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam 05May2010 2010 doi:10.2903/j.efsa.2010.1592
+Metosulam 139528-85-1 single chemical entity Component is identical to the substance Metosulam 139528-85-1 N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide Metosulam C14H13Cl2N5O4S Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(cc(OC)n2n1)OC InChI=1S/C14H13Cl2N5O4S/c1-7-4-5-8(15)12(11(7)16)20-26(22,23)14-18-13-17-9(24-2)6-10(25-3)21(13)19-14/h4-6,20H,1-3H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: France Metosulam 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam 05May2010 2010 doi:10.2903/j.efsa.2010.1592
+Metosulam 139528-85-1 single chemical entity Component is identical to the substance Metosulam 139528-85-1 N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide Metosulam C14H13Cl2N5O4S Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(cc(OC)n2n1)OC InChI=1S/C14H13Cl2N5O4S/c1-7-4-5-8(15)12(11(7)16)20-26(22,23)14-18-13-17-9(24-2)6-10(25-3)21(13)19-14/h4-6,20H,1-3H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: France Metosulam 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam 05May2010 2010 doi:10.2903/j.efsa.2010.1592
+Metosulam 139528-85-1 single chemical entity Component is identical to the substance Metosulam 139528-85-1 N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide Metosulam C14H13Cl2N5O4S Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(cc(OC)n2n1)OC InChI=1S/C14H13Cl2N5O4S/c1-7-4-5-8(15)12(11(7)16)20-26(22,23)14-18-13-17-9(24-2)6-10(25-3)21(13)19-14/h4-6,20H,1-3H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: France Metosulam 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam 05May2010 2010 doi:10.2903/j.efsa.2010.1592
+Metosulam 139528-85-1 single chemical entity Component is identical to the substance Metosulam 139528-85-1 N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide Metosulam C14H13Cl2N5O4S Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(cc(OC)n2n1)OC InChI=1S/C14H13Cl2N5O4S/c1-7-4-5-8(15)12(11(7)16)20-26(22,23)14-18-13-17-9(24-2)6-10(25-3)21(13)19-14/h4-6,20H,1-3H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Rat (as animal) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: France Metosulam 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam 05May2010 2010 doi:10.2903/j.efsa.2010.1592
+Metosulam 139528-85-1 single chemical entity Component is identical to the substance Metosulam 139528-85-1 N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide Metosulam C14H13Cl2N5O4S Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(cc(OC)n2n1)OC InChI=1S/C14H13Cl2N5O4S/c1-7-4-5-8(15)12(11(7)16)20-26(22,23)14-18-13-17-9(24-2)6-10(25-3)21(13)19-14/h4-6,20H,1-3H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Rat (as animal) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: France Metosulam 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam 05May2010 2010 doi:10.2903/j.efsa.2010.1592
+Metosulam 139528-85-1 single chemical entity Component is identical to the substance Metosulam 139528-85-1 N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide Metosulam C14H13Cl2N5O4S Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(cc(OC)n2n1)OC InChI=1S/C14H13Cl2N5O4S/c1-7-4-5-8(15)12(11(7)16)20-26(22,23)14-18-13-17-9(24-2)6-10(25-3)21(13)19-14/h4-6,20H,1-3H3 organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: France Metosulam 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam 05May2010 2010 doi:10.2903/j.efsa.2010.1592
+Metosulam 139528-85-1 single chemical entity Component is identical to the substance Metosulam 139528-85-1 N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide Metosulam C14H13Cl2N5O4S Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(cc(OC)n2n1)OC InChI=1S/C14H13Cl2N5O4S/c1-7-4-5-8(15)12(11(7)16)20-26(22,23)14-18-13-17-9(24-2)6-10(25-3)21(13)19-14/h4-6,20H,1-3H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 30 Male/Female oral: gavage 72.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: France Metosulam 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam 05May2010 2010 doi:10.2903/j.efsa.2010.1592
+Metosulam 139528-85-1 single chemical entity Component is identical to the substance Metosulam 139528-85-1 N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide Metosulam C14H13Cl2N5O4S Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(cc(OC)n2n1)OC InChI=1S/C14H13Cl2N5O4S/c1-7-4-5-8(15)12(11(7)16)20-26(22,23)14-18-13-17-9(24-2)6-10(25-3)21(13)19-14/h4-6,20H,1-3H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 30 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: France Metosulam 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam 05May2010 2010 doi:10.2903/j.efsa.2010.1592
+Metosulam 139528-85-1 single chemical entity Component is identical to the substance Metosulam 139528-85-1 N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide Metosulam C14H13Cl2N5O4S Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(cc(OC)n2n1)OC InChI=1S/C14H13Cl2N5O4S/c1-7-4-5-8(15)12(11(7)16)20-26(22,23)14-18-13-17-9(24-2)6-10(25-3)21(13)19-14/h4-6,20H,1-3H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 30 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: France Metosulam 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam 05May2010 2010 doi:10.2903/j.efsa.2010.1592
+Metosulam 139528-85-1 single chemical entity Component is a metabolite of the substance 5-Amino-N-(2,6-dichloro-3-methylphenyl)-1H-1,2,4-triazole-3-sulfonamide 5-amino-N-(2,6-dichloro-3-methylphenyl)-1H-1,2,4-triazole-3-sulfonamide Not in list C9H9Cl2N5O2S O=S(=O)(Nc1c(Cl)c(C)ccc1Cl)c2nc(N)nn2 InChI=1S/C9H9Cl2N5O2S/c1-4-2-3-5(10)7(6(4)11)16-19(17,18)9-13-8(12)14-15-9/h2-3,16H,1H3,(H3,12,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Metosulam 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam 05May2010 2010 doi:10.2903/j.efsa.2010.1592
+Metosulam 139528-85-1 single chemical entity Component is a metabolite of the substance 5-Amino-N-(2,6-dichloro-3-methylphenyl)-1H-1,2,4-triazole-3-sulfonamide 5-amino-N-(2,6-dichloro-3-methylphenyl)-1H-1,2,4-triazole-3-sulfonamide Not in list C9H9Cl2N5O2S O=S(=O)(Nc1c(Cl)c(C)ccc1Cl)c2nc(N)nn2 InChI=1S/C9H9Cl2N5O2S/c1-4-2-3-5(10)7(6(4)11)16-19(17,18)9-13-8(12)14-15-9/h2-3,16H,1H3,(H3,12,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Metosulam 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam 05May2010 2010 doi:10.2903/j.efsa.2010.1592
+Metosulam 139528-85-1 single chemical entity Component is a metabolite of the substance 5-Amino-N-(2,6-dichloro-3-methylphenyl)-1H-1,2,4-triazole-3-sulfonamide 5-amino-N-(2,6-dichloro-3-methylphenyl)-1H-1,2,4-triazole-3-sulfonamide Not in list C9H9Cl2N5O2S O=S(=O)(Nc1c(Cl)c(C)ccc1Cl)c2nc(N)nn2 InChI=1S/C9H9Cl2N5O2S/c1-4-2-3-5(10)7(6(4)11)16-19(17,18)9-13-8(12)14-15-9/h2-3,16H,1H3,(H3,12,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Metosulam 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam 05May2010 2010 doi:10.2903/j.efsa.2010.1592
+Metosulam 139528-85-1 single chemical entity Component is a metabolite of the substance 5-Amino-N-(2,6-dichloro-3-methylphenyl)-1H-1,2,4-triazole-3-sulfonamide 5-amino-N-(2,6-dichloro-3-methylphenyl)-1H-1,2,4-triazole-3-sulfonamide Not in list C9H9Cl2N5O2S O=S(=O)(Nc1c(Cl)c(C)ccc1Cl)c2nc(N)nn2 InChI=1S/C9H9Cl2N5O2S/c1-4-2-3-5(10)7(6(4)11)16-19(17,18)9-13-8(12)14-15-9/h2-3,16H,1H3,(H3,12,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Metosulam 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam 05May2010 2010 doi:10.2903/j.efsa.2010.1592
+Metosulam 139528-85-1 single chemical entity Component is a metabolite of the substance 5-Amino-N-(2,6-dichloro-3-methylphenyl)-1H-1,2,4-triazole-3-sulfonamide 5-amino-N-(2,6-dichloro-3-methylphenyl)-1H-1,2,4-triazole-3-sulfonamide Not in list C9H9Cl2N5O2S O=S(=O)(Nc1c(Cl)c(C)ccc1Cl)c2nc(N)nn2 InChI=1S/C9H9Cl2N5O2S/c1-4-2-3-5(10)7(6(4)11)16-19(17,18)9-13-8(12)14-15-9/h2-3,16H,1H3,(H3,12,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Metosulam 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam 05May2010 2010 doi:10.2903/j.efsa.2010.1592
+Metosulam 139528-85-1 single chemical entity Component is a metabolite of the substance 5-Amino-N-(2,6-dichloro-3-methylphenyl)-1H-1,2,4-triazole-3-sulfonamide 5-amino-N-(2,6-dichloro-3-methylphenyl)-1H-1,2,4-triazole-3-sulfonamide Not in list C9H9Cl2N5O2S O=S(=O)(Nc1c(Cl)c(C)ccc1Cl)c2nc(N)nn2 InChI=1S/C9H9Cl2N5O2S/c1-4-2-3-5(10)7(6(4)11)16-19(17,18)9-13-8(12)14-15-9/h2-3,16H,1H3,(H3,12,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: France Metosulam 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam 05May2010 2010 doi:10.2903/j.efsa.2010.1592
+Metosulam 139528-85-1 single chemical entity Component is a metabolite of the substance 5-Amino-N-(2,6-dichloro-3-methylphenyl)-1H-1,2,4-triazole-3-sulfonamide 5-amino-N-(2,6-dichloro-3-methylphenyl)-1H-1,2,4-triazole-3-sulfonamide Not in list C9H9Cl2N5O2S O=S(=O)(Nc1c(Cl)c(C)ccc1Cl)c2nc(N)nn2 InChI=1S/C9H9Cl2N5O2S/c1-4-2-3-5(10)7(6(4)11)16-19(17,18)9-13-8(12)14-15-9/h2-3,16H,1H3,(H3,12,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: France Metosulam 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam 05May2010 2010 doi:10.2903/j.efsa.2010.1592
+Metosulam 139528-85-1 single chemical entity Component is a metabolite of the substance 5-Amino-N-(2,6-dichloro-3-methylphenyl)-1H-1,2,4-triazole-3-sulfonamide 5-amino-N-(2,6-dichloro-3-methylphenyl)-1H-1,2,4-triazole-3-sulfonamide Not in list C9H9Cl2N5O2S O=S(=O)(Nc1c(Cl)c(C)ccc1Cl)c2nc(N)nn2 InChI=1S/C9H9Cl2N5O2S/c1-4-2-3-5(10)7(6(4)11)16-19(17,18)9-13-8(12)14-15-9/h2-3,16H,1H3,(H3,12,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Metosulam 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam 05May2010 2010 doi:10.2903/j.efsa.2010.1592
+Metosulam 139528-85-1 single chemical entity Component is a metabolite of the substance 5-Amino-N-(2,6-dichloro-3-methylphenyl)-1H-1,2,4-triazole-3-sulfonamide 5-amino-N-(2,6-dichloro-3-methylphenyl)-1H-1,2,4-triazole-3-sulfonamide Not in list C9H9Cl2N5O2S O=S(=O)(Nc1c(Cl)c(C)ccc1Cl)c2nc(N)nn2 InChI=1S/C9H9Cl2N5O2S/c1-4-2-3-5(10)7(6(4)11)16-19(17,18)9-13-8(12)14-15-9/h2-3,16H,1H3,(H3,12,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Metosulam 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam 05May2010 2010 doi:10.2903/j.efsa.2010.1592
+Metosulam 139528-85-1 single chemical entity Component is a metabolite of the substance 5-Amino-N-(2,6-dichloro-3-methylphenyl)-1H-1,2,4-triazole-3-sulfonamide 5-amino-N-(2,6-dichloro-3-methylphenyl)-1H-1,2,4-triazole-3-sulfonamide Not in list C9H9Cl2N5O2S O=S(=O)(Nc1c(Cl)c(C)ccc1Cl)c2nc(N)nn2 InChI=1S/C9H9Cl2N5O2S/c1-4-2-3-5(10)7(6(4)11)16-19(17,18)9-13-8(12)14-15-9/h2-3,16H,1H3,(H3,12,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Metosulam 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam 05May2010 2010 doi:10.2903/j.efsa.2010.1592
+Metosulam 139528-85-1 single chemical entity Component is a metabolite of the substance N-(2,6-dichloro-3-methylphenyl)-7-hydroxy-5-methoxy[1,2,4] triazolo[1,5-a]pyrimidine-2-sulfonamide N-(2,6-dichloro-3-methylphenyl)-7-hydroxy-5-methoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide Not in list C13H11Cl2N5O4S Clc1c(C)ccc(Cl)c1NS(=O)(=O)c2nc3nc(cc(O)n3n2)OC InChI=1S/C13H11Cl2N5O4S/c1-6-3-4-7(14)11(10(6)15)19-25(22,23)13-17-12-16-8(24-2)5-9(21)20(12)18-13/h3-5,19,21H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Metosulam 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam 05May2010 2010 doi:10.2903/j.efsa.2010.1592
+Metosulam 139528-85-1 single chemical entity Component is a metabolite of the substance N-(2,6-dichloro-3-methylphenyl)-7-hydroxy-5-methoxy[1,2,4] triazolo[1,5-a]pyrimidine-2-sulfonamide N-(2,6-dichloro-3-methylphenyl)-7-hydroxy-5-methoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide Not in list C13H11Cl2N5O4S Clc1c(C)ccc(Cl)c1NS(=O)(=O)c2nc3nc(cc(O)n3n2)OC InChI=1S/C13H11Cl2N5O4S/c1-6-3-4-7(14)11(10(6)15)19-25(22,23)13-17-12-16-8(24-2)5-9(21)20(12)18-13/h3-5,19,21H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Metosulam 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam 05May2010 2010 doi:10.2903/j.efsa.2010.1592
+Metosulam 139528-85-1 single chemical entity Component is a metabolite of the substance N-(2,6-dichloro-3-methylphenyl)-7-hydroxy-5-methoxy[1,2,4] triazolo[1,5-a]pyrimidine-2-sulfonamide N-(2,6-dichloro-3-methylphenyl)-7-hydroxy-5-methoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide Not in list C13H11Cl2N5O4S Clc1c(C)ccc(Cl)c1NS(=O)(=O)c2nc3nc(cc(O)n3n2)OC InChI=1S/C13H11Cl2N5O4S/c1-6-3-4-7(14)11(10(6)15)19-25(22,23)13-17-12-16-8(24-2)5-9(21)20(12)18-13/h3-5,19,21H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Metosulam 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam 05May2010 2010 doi:10.2903/j.efsa.2010.1592
+Metosulam 139528-85-1 single chemical entity Component is a metabolite of the substance N-(2,6-dichloro-3-methylphenyl)-7-hydroxy-5-methoxy[1,2,4] triazolo[1,5-a]pyrimidine-2-sulfonamide N-(2,6-dichloro-3-methylphenyl)-7-hydroxy-5-methoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide Not in list C13H11Cl2N5O4S Clc1c(C)ccc(Cl)c1NS(=O)(=O)c2nc3nc(cc(O)n3n2)OC InChI=1S/C13H11Cl2N5O4S/c1-6-3-4-7(14)11(10(6)15)19-25(22,23)13-17-12-16-8(24-2)5-9(21)20(12)18-13/h3-5,19,21H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Metosulam 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam 05May2010 2010 doi:10.2903/j.efsa.2010.1592
+Metosulam 139528-85-1 single chemical entity Component is a metabolite of the substance N-(2,6-dichloro-3-methylphenyl)-7-hydroxy-5-methoxy[1,2,4] triazolo[1,5-a]pyrimidine-2-sulfonamide N-(2,6-dichloro-3-methylphenyl)-7-hydroxy-5-methoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide Not in list C13H11Cl2N5O4S Clc1c(C)ccc(Cl)c1NS(=O)(=O)c2nc3nc(cc(O)n3n2)OC InChI=1S/C13H11Cl2N5O4S/c1-6-3-4-7(14)11(10(6)15)19-25(22,23)13-17-12-16-8(24-2)5-9(21)20(12)18-13/h3-5,19,21H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: France Metosulam 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam 05May2010 2010 doi:10.2903/j.efsa.2010.1592
+Metosulam 139528-85-1 single chemical entity Component is a metabolite of the substance N-(2,6-dichloro-3-methylphenyl)-7-hydroxy-5-methoxy[1,2,4] triazolo[1,5-a]pyrimidine-2-sulfonamide N-(2,6-dichloro-3-methylphenyl)-7-hydroxy-5-methoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide Not in list C13H11Cl2N5O4S Clc1c(C)ccc(Cl)c1NS(=O)(=O)c2nc3nc(cc(O)n3n2)OC InChI=1S/C13H11Cl2N5O4S/c1-6-3-4-7(14)11(10(6)15)19-25(22,23)13-17-12-16-8(24-2)5-9(21)20(12)18-13/h3-5,19,21H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Metosulam 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam 05May2010 2010 doi:10.2903/j.efsa.2010.1592
+Metosulam 139528-85-1 single chemical entity Component is a metabolite of the substance N-(2,6-dichloro-3-methylphenyl)-7-hydroxy-5-methoxy[1,2,4] triazolo[1,5-a]pyrimidine-2-sulfonamide N-(2,6-dichloro-3-methylphenyl)-7-hydroxy-5-methoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide Not in list C13H11Cl2N5O4S Clc1c(C)ccc(Cl)c1NS(=O)(=O)c2nc3nc(cc(O)n3n2)OC InChI=1S/C13H11Cl2N5O4S/c1-6-3-4-7(14)11(10(6)15)19-25(22,23)13-17-12-16-8(24-2)5-9(21)20(12)18-13/h3-5,19,21H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Metosulam 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam 05May2010 2010 doi:10.2903/j.efsa.2010.1592
+Metosulam 139528-85-1 single chemical entity Component is a metabolite of the substance N-(2,6-dichloro-3-methylphenyl)-7-hydroxy-5-methoxy[1,2,4] triazolo[1,5-a]pyrimidine-2-sulfonamide N-(2,6-dichloro-3-methylphenyl)-7-hydroxy-5-methoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide Not in list C13H11Cl2N5O4S Clc1c(C)ccc(Cl)c1NS(=O)(=O)c2nc3nc(cc(O)n3n2)OC InChI=1S/C13H11Cl2N5O4S/c1-6-3-4-7(14)11(10(6)15)19-25(22,23)13-17-12-16-8(24-2)5-9(21)20(12)18-13/h3-5,19,21H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Metosulam 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam 05May2010 2010 doi:10.2903/j.efsa.2010.1592
+Metosulam 139528-85-1 single chemical entity Component is a metabolite of the substance N-(2,6-dichloro-3-methylphenyl)-7-hydroxy-5-methoxy[1,2,4] triazolo[1,5-a]pyrimidine-2-sulfonamide N-(2,6-dichloro-3-methylphenyl)-7-hydroxy-5-methoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide Not in list C13H11Cl2N5O4S Clc1c(C)ccc(Cl)c1NS(=O)(=O)c2nc3nc(cc(O)n3n2)OC InChI=1S/C13H11Cl2N5O4S/c1-6-3-4-7(14)11(10(6)15)19-25(22,23)13-17-12-16-8(24-2)5-9(21)20(12)18-13/h3-5,19,21H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: France Metosulam 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam 05May2010 2010 doi:10.2903/j.efsa.2010.1592
+Metosulam 139528-85-1 single chemical entity Component is a metabolite of the substance N-(2,6-dichloro-3-methylphenyl)-7-hydroxy-5-methoxy[1,2,4] triazolo[1,5-a]pyrimidine-2-sulfonamide N-(2,6-dichloro-3-methylphenyl)-7-hydroxy-5-methoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide Not in list C13H11Cl2N5O4S Clc1c(C)ccc(Cl)c1NS(=O)(=O)c2nc3nc(cc(O)n3n2)OC InChI=1S/C13H11Cl2N5O4S/c1-6-3-4-7(14)11(10(6)15)19-25(22,23)13-17-12-16-8(24-2)5-9(21)20(12)18-13/h3-5,19,21H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Metosulam 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam 05May2010 2010 doi:10.2903/j.efsa.2010.1592
+Metosulam 139528-85-1 single chemical entity Component is a metabolite of the substance N-(2,6-dichloro-3-methylphenyl)-5,7-dihydroxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide N-(2,6-dichloro-3-methylphenyl)-5,7-dihydroxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide Not in list C12H9Cl2N5O4S Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(O)cc(O)n2n1 InChI=1S/C12H9Cl2N5O4S/c1-5-2-3-6(13)10(9(5)14)18-24(22,23)12-16-11-15-7(20)4-8(21)19(11)17-12/h2-4,18,21H,1H3,(H,15,16,17,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: France Metosulam 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam 05May2010 2010 doi:10.2903/j.efsa.2010.1592
+Metosulam 139528-85-1 single chemical entity Component is a metabolite of the substance N-(2,6-dichloro-3-methylphenyl)-5,7-dihydroxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide N-(2,6-dichloro-3-methylphenyl)-5,7-dihydroxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide Not in list C12H9Cl2N5O4S Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(O)cc(O)n2n1 InChI=1S/C12H9Cl2N5O4S/c1-5-2-3-6(13)10(9(5)14)18-24(22,23)12-16-11-15-7(20)4-8(21)19(11)17-12/h2-4,18,21H,1H3,(H,15,16,17,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Metosulam 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam 05May2010 2010 doi:10.2903/j.efsa.2010.1592
+Metosulam 139528-85-1 single chemical entity Component is a metabolite of the substance N-(2,6-dichloro-3-methylphenyl)-5,7-dihydroxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide N-(2,6-dichloro-3-methylphenyl)-5,7-dihydroxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide Not in list C12H9Cl2N5O4S Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(O)cc(O)n2n1 InChI=1S/C12H9Cl2N5O4S/c1-5-2-3-6(13)10(9(5)14)18-24(22,23)12-16-11-15-7(20)4-8(21)19(11)17-12/h2-4,18,21H,1H3,(H,15,16,17,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Metosulam 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam 05May2010 2010 doi:10.2903/j.efsa.2010.1592
+Metosulam 139528-85-1 single chemical entity Component is a metabolite of the substance N-(2,6-dichloro-3-methylphenyl)-5,7-dihydroxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide N-(2,6-dichloro-3-methylphenyl)-5,7-dihydroxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide Not in list C12H9Cl2N5O4S Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(O)cc(O)n2n1 InChI=1S/C12H9Cl2N5O4S/c1-5-2-3-6(13)10(9(5)14)18-24(22,23)12-16-11-15-7(20)4-8(21)19(11)17-12/h2-4,18,21H,1H3,(H,15,16,17,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Metosulam 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam 05May2010 2010 doi:10.2903/j.efsa.2010.1592
+Metosulam 139528-85-1 single chemical entity Component is a metabolite of the substance N-(2,6-dichloro-3-methylphenyl)-5,7-dihydroxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide N-(2,6-dichloro-3-methylphenyl)-5,7-dihydroxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide Not in list C12H9Cl2N5O4S Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(O)cc(O)n2n1 InChI=1S/C12H9Cl2N5O4S/c1-5-2-3-6(13)10(9(5)14)18-24(22,23)12-16-11-15-7(20)4-8(21)19(11)17-12/h2-4,18,21H,1H3,(H,15,16,17,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Metosulam 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam 05May2010 2010 doi:10.2903/j.efsa.2010.1592
+Metosulam 139528-85-1 single chemical entity Component is a metabolite of the substance N-(2,6-dichloro-3-methylphenyl)-5,7-dihydroxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide N-(2,6-dichloro-3-methylphenyl)-5,7-dihydroxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide Not in list C12H9Cl2N5O4S Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(O)cc(O)n2n1 InChI=1S/C12H9Cl2N5O4S/c1-5-2-3-6(13)10(9(5)14)18-24(22,23)12-16-11-15-7(20)4-8(21)19(11)17-12/h2-4,18,21H,1H3,(H,15,16,17,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Metosulam 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam 05May2010 2010 doi:10.2903/j.efsa.2010.1592
+Metosulam 139528-85-1 single chemical entity Component is a metabolite of the substance N-(2,6-dichloro-3-methylphenyl)-5,7-dihydroxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide N-(2,6-dichloro-3-methylphenyl)-5,7-dihydroxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide Not in list C12H9Cl2N5O4S Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(O)cc(O)n2n1 InChI=1S/C12H9Cl2N5O4S/c1-5-2-3-6(13)10(9(5)14)18-24(22,23)12-16-11-15-7(20)4-8(21)19(11)17-12/h2-4,18,21H,1H3,(H,15,16,17,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Metosulam 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam 05May2010 2010 doi:10.2903/j.efsa.2010.1592
+Metosulam 139528-85-1 single chemical entity Component is a metabolite of the substance N-(2,6-dichloro-3-methylphenyl)-5,7-dihydroxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide N-(2,6-dichloro-3-methylphenyl)-5,7-dihydroxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide Not in list C12H9Cl2N5O4S Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(O)cc(O)n2n1 InChI=1S/C12H9Cl2N5O4S/c1-5-2-3-6(13)10(9(5)14)18-24(22,23)12-16-11-15-7(20)4-8(21)19(11)17-12/h2-4,18,21H,1H3,(H,15,16,17,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Metosulam 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam 05May2010 2010 doi:10.2903/j.efsa.2010.1592
+Metosulam 139528-85-1 single chemical entity Component is a metabolite of the substance N-(2,6-dichloro-3-methylphenyl)-5,7-dihydroxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide N-(2,6-dichloro-3-methylphenyl)-5,7-dihydroxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide Not in list C12H9Cl2N5O4S Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(O)cc(O)n2n1 InChI=1S/C12H9Cl2N5O4S/c1-5-2-3-6(13)10(9(5)14)18-24(22,23)12-16-11-15-7(20)4-8(21)19(11)17-12/h2-4,18,21H,1H3,(H,15,16,17,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Metosulam 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam 05May2010 2010 doi:10.2903/j.efsa.2010.1592
+Metosulam 139528-85-1 single chemical entity Component is a metabolite of the substance N-(2,6-dichloro-3-methylphenyl)-5,7-dihydroxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide N-(2,6-dichloro-3-methylphenyl)-5,7-dihydroxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide Not in list C12H9Cl2N5O4S Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(O)cc(O)n2n1 InChI=1S/C12H9Cl2N5O4S/c1-5-2-3-6(13)10(9(5)14)18-24(22,23)12-16-11-15-7(20)4-8(21)19(11)17-12/h2-4,18,21H,1H3,(H,15,16,17,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: France Metosulam 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam 05May2010 2010 doi:10.2903/j.efsa.2010.1592
+Metosulam 139528-85-1 single chemical entity Component is identical to the substance Metosulam 139528-85-1 N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide Metosulam C14H13Cl2N5O4S Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(cc(OC)n2n1)OC InChI=1S/C14H13Cl2N5O4S/c1-7-4-5-8(15)12(11(7)16)20-26(22,23)14-18-13-17-9(24-2)6-10(25-3)21(13)19-14/h4-6,20H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Metosulam (Addendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam 05May2010 2010 doi:10.2903/j.efsa.2010.1592
+Metosulam 139528-85-1 single chemical entity Component is identical to the substance Metosulam 139528-85-1 N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide Metosulam C14H13Cl2N5O4S Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(cc(OC)n2n1)OC InChI=1S/C14H13Cl2N5O4S/c1-7-4-5-8(15)12(11(7)16)20-26(22,23)14-18-13-17-9(24-2)6-10(25-3)21(13)19-14/h4-6,20H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Metosulam (Addendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam 05May2010 2010 doi:10.2903/j.efsa.2010.1592
+Metosulam 139528-85-1 single chemical entity Component is identical to the substance Metosulam 139528-85-1 N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide Metosulam C14H13Cl2N5O4S Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(cc(OC)n2n1)OC InChI=1S/C14H13Cl2N5O4S/c1-7-4-5-8(15)12(11(7)16)20-26(22,23)14-18-13-17-9(24-2)6-10(25-3)21(13)19-14/h4-6,20H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: France Metosulam (Addendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam 05May2010 2010 doi:10.2903/j.efsa.2010.1592
+Metosulam 139528-85-1 single chemical entity Component is identical to the substance Metosulam 139528-85-1 N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide Metosulam C14H13Cl2N5O4S Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(cc(OC)n2n1)OC InChI=1S/C14H13Cl2N5O4S/c1-7-4-5-8(15)12(11(7)16)20-26(22,23)14-18-13-17-9(24-2)6-10(25-3)21(13)19-14/h4-6,20H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Metosulam (Addendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam 05May2010 2010 doi:10.2903/j.efsa.2010.1592
+Metosulam 139528-85-1 single chemical entity Component is identical to the substance Metosulam 139528-85-1 N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide Metosulam C14H13Cl2N5O4S Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(cc(OC)n2n1)OC InChI=1S/C14H13Cl2N5O4S/c1-7-4-5-8(15)12(11(7)16)20-26(22,23)14-18-13-17-9(24-2)6-10(25-3)21(13)19-14/h4-6,20H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Metosulam (Addendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam 05May2010 2010 doi:10.2903/j.efsa.2010.1592
+Metosulam 139528-85-1 single chemical entity Component is identical to the substance Metosulam 139528-85-1 N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide Metosulam C14H13Cl2N5O4S Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(cc(OC)n2n1)OC InChI=1S/C14H13Cl2N5O4S/c1-7-4-5-8(15)12(11(7)16)20-26(22,23)14-18-13-17-9(24-2)6-10(25-3)21(13)19-14/h4-6,20H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Metosulam (Addendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam 05May2010 2010 doi:10.2903/j.efsa.2010.1592
+Metosulam 139528-85-1 single chemical entity Component is identical to the substance Metosulam 139528-85-1 N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide Metosulam C14H13Cl2N5O4S Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(cc(OC)n2n1)OC InChI=1S/C14H13Cl2N5O4S/c1-7-4-5-8(15)12(11(7)16)20-26(22,23)14-18-13-17-9(24-2)6-10(25-3)21(13)19-14/h4-6,20H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Metosulam (Addendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam 05May2010 2010 doi:10.2903/j.efsa.2010.1592
+Metosulam 139528-85-1 single chemical entity Component is identical to the substance Metosulam 139528-85-1 N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide Metosulam C14H13Cl2N5O4S Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(cc(OC)n2n1)OC InChI=1S/C14H13Cl2N5O4S/c1-7-4-5-8(15)12(11(7)16)20-26(22,23)14-18-13-17-9(24-2)6-10(25-3)21(13)19-14/h4-6,20H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: France Metosulam (Addendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam 05May2010 2010 doi:10.2903/j.efsa.2010.1592
+Metosulam 139528-85-1 single chemical entity Component is identical to the substance Metosulam 139528-85-1 N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide Metosulam C14H13Cl2N5O4S Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(cc(OC)n2n1)OC InChI=1S/C14H13Cl2N5O4S/c1-7-4-5-8(15)12(11(7)16)20-26(22,23)14-18-13-17-9(24-2)6-10(25-3)21(13)19-14/h4-6,20H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Metosulam (Addendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam 05May2010 2010 doi:10.2903/j.efsa.2010.1592
+Metosulam 139528-85-1 single chemical entity Component is identical to the substance Metosulam 139528-85-1 N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide Metosulam C14H13Cl2N5O4S Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(cc(OC)n2n1)OC InChI=1S/C14H13Cl2N5O4S/c1-7-4-5-8(15)12(11(7)16)20-26(22,23)14-18-13-17-9(24-2)6-10(25-3)21(13)19-14/h4-6,20H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Metosulam (Addendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam 05May2010 2010 doi:10.2903/j.efsa.2010.1592
+Metosulam 139528-85-1 single chemical entity Component is identical to the substance Metosulam 139528-85-1 N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide Metosulam C14H13Cl2N5O4S Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(cc(OC)n2n1)OC InChI=1S/C14H13Cl2N5O4S/c1-7-4-5-8(15)12(11(7)16)20-26(22,23)14-18-13-17-9(24-2)6-10(25-3)21(13)19-14/h4-6,20H,1-3H3 organic compound Other Other DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo Equivalent or similar to OECD Guideline 489 Yes Acceptable Rat (as animal) Sprague-Dawley 10 Male oral: gavage 20.0000000000 h yes, concurrent vehicle not applicable Negative RMS: France Metosulam (Addendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam 05May2010 2010 doi:10.2903/j.efsa.2010.1592
+Metosulam 139528-85-1 single chemical entity Component is identical to the substance Metosulam 139528-85-1 N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide Metosulam C14H13Cl2N5O4S Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(cc(OC)n2n1)OC InChI=1S/C14H13Cl2N5O4S/c1-7-4-5-8(15)12(11(7)16)20-26(22,23)14-18-13-17-9(24-2)6-10(25-3)21(13)19-14/h4-6,20H,1-3H3 organic compound Other Other DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo Equivalent or similar to OECD Guideline 489 Yes Acceptable Rat (as animal) Sprague-Dawley 10 Male oral: gavage 3.0000000000 h yes, concurrent vehicle not applicable Negative RMS: France Metosulam (Addendum) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam 05May2010 2010 doi:10.2903/j.efsa.2010.1592
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is identical to the substance Metaflumizone 604-167-6 139968-49-3 1-[(E)-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]amino]-3-[4-(trifluoromethoxy)phenyl]urea Metaflumizone (sum of E- and Z- isomers) C24H16F6N4O2 C1=CC(=CC(=C1)C(F)(F)F)C(=NNC(=O)NC2=CC=C(C=C2)OC(F)(F)F)CC3=CC=C(C=C3)C#N InChI=1S/C24H16F6N4O2/c25-23(26,27)18-3-1-2-17(13-18)21(12-15-4-6-16(14-31)7-5-15)33-34-22(35)32-19-8-10-20(11-9-19)36-24(28,29)30/h1-11,13H,12H2,(H2,32,34,35)/b33-21+ organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is identical to the substance Metaflumizone 604-167-6 139968-49-3 1-[(E)-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]amino]-3-[4-(trifluoromethoxy)phenyl]urea Metaflumizone (sum of E- and Z- isomers) C24H16F6N4O2 C1=CC(=CC(=C1)C(F)(F)F)C(=NNC(=O)NC2=CC=C(C=C2)OC(F)(F)F)CC3=CC=C(C=C3)C#N InChI=1S/C24H16F6N4O2/c25-23(26,27)18-3-1-2-17(13-18)21(12-15-4-6-16(14-31)7-5-15)33-34-22(35)32-19-8-10-20(11-9-19)36-24(28,29)30/h1-11,13H,12H2,(H2,32,34,35)/b33-21+ organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is identical to the substance Metaflumizone 604-167-6 139968-49-3 1-[(E)-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]amino]-3-[4-(trifluoromethoxy)phenyl]urea Metaflumizone (sum of E- and Z- isomers) C24H16F6N4O2 C1=CC(=CC(=C1)C(F)(F)F)C(=NNC(=O)NC2=CC=C(C=C2)OC(F)(F)F)CC3=CC=C(C=C3)C#N InChI=1S/C24H16F6N4O2/c25-23(26,27)18-3-1-2-17(13-18)21(12-15-4-6-16(14-31)7-5-15)33-34-22(35)32-19-8-10-20(11-9-19)36-24(28,29)30/h1-11,13H,12H2,(H2,32,34,35)/b33-21+ organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is identical to the substance Metaflumizone 604-167-6 139968-49-3 1-[(E)-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]amino]-3-[4-(trifluoromethoxy)phenyl]urea Metaflumizone (sum of E- and Z- isomers) C24H16F6N4O2 C1=CC(=CC(=C1)C(F)(F)F)C(=NNC(=O)NC2=CC=C(C=C2)OC(F)(F)F)CC3=CC=C(C=C3)C#N InChI=1S/C24H16F6N4O2/c25-23(26,27)18-3-1-2-17(13-18)21(12-15-4-6-16(14-31)7-5-15)33-34-22(35)32-19-8-10-20(11-9-19)36-24(28,29)30/h1-11,13H,12H2,(H2,32,34,35)/b33-21+ organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is identical to the substance Metaflumizone 604-167-6 139968-49-3 1-[(E)-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]amino]-3-[4-(trifluoromethoxy)phenyl]urea Metaflumizone (sum of E- and Z- isomers) C24H16F6N4O2 C1=CC(=CC(=C1)C(F)(F)F)C(=NNC(=O)NC2=CC=C(C=C2)OC(F)(F)F)CC3=CC=C(C=C3)C#N InChI=1S/C24H16F6N4O2/c25-23(26,27)18-3-1-2-17(13-18)21(12-15-4-6-16(14-31)7-5-15)33-34-22(35)32-19-8-10-20(11-9-19)36-24(28,29)30/h1-11,13H,12H2,(H2,32,34,35)/b33-21+ organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is identical to the substance Metaflumizone 604-167-6 139968-49-3 1-[(E)-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]amino]-3-[4-(trifluoromethoxy)phenyl]urea Metaflumizone (sum of E- and Z- isomers) C24H16F6N4O2 C1=CC(=CC(=C1)C(F)(F)F)C(=NNC(=O)NC2=CC=C(C=C2)OC(F)(F)F)CC3=CC=C(C=C3)C#N InChI=1S/C24H16F6N4O2/c25-23(26,27)18-3-1-2-17(13-18)21(12-15-4-6-16(14-31)7-5-15)33-34-22(35)32-19-8-10-20(11-9-19)36-24(28,29)30/h1-11,13H,12H2,(H2,32,34,35)/b33-21+ organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is identical to the substance Metaflumizone 604-167-6 139968-49-3 1-[(E)-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]amino]-3-[4-(trifluoromethoxy)phenyl]urea Metaflumizone (sum of E- and Z- isomers) C24H16F6N4O2 C1=CC(=CC(=C1)C(F)(F)F)C(=NNC(=O)NC2=CC=C(C=C2)OC(F)(F)F)CC3=CC=C(C=C3)C#N InChI=1S/C24H16F6N4O2/c25-23(26,27)18-3-1-2-17(13-18)21(12-15-4-6-16(14-31)7-5-15)33-34-22(35)32-19-8-10-20(11-9-19)36-24(28,29)30/h1-11,13H,12H2,(H2,32,34,35)/b33-21+ organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is identical to the substance Metaflumizone 604-167-6 139968-49-3 1-[(E)-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]amino]-3-[4-(trifluoromethoxy)phenyl]urea Metaflumizone (sum of E- and Z- isomers) C24H16F6N4O2 C1=CC(=CC(=C1)C(F)(F)F)C(=NNC(=O)NC2=CC=C(C=C2)OC(F)(F)F)CC3=CC=C(C=C3)C#N InChI=1S/C24H16F6N4O2/c25-23(26,27)18-3-1-2-17(13-18)21(12-15-4-6-16(14-31)7-5-15)33-34-22(35)32-19-8-10-20(11-9-19)36-24(28,29)30/h1-11,13H,12H2,(H2,32,34,35)/b33-21+ organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is identical to the substance Metaflumizone 604-167-6 139968-49-3 1-[(E)-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]amino]-3-[4-(trifluoromethoxy)phenyl]urea Metaflumizone (sum of E- and Z- isomers) C24H16F6N4O2 C1=CC(=CC(=C1)C(F)(F)F)C(=NNC(=O)NC2=CC=C(C=C2)OC(F)(F)F)CC3=CC=C(C=C3)C#N InChI=1S/C24H16F6N4O2/c25-23(26,27)18-3-1-2-17(13-18)21(12-15-4-6-16(14-31)7-5-15)33-34-22(35)32-19-8-10-20(11-9-19)36-24(28,29)30/h1-11,13H,12H2,(H2,32,34,35)/b33-21+ organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is identical to the substance Metaflumizone 604-167-6 139968-49-3 1-[(E)-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]amino]-3-[4-(trifluoromethoxy)phenyl]urea Metaflumizone (sum of E- and Z- isomers) C24H16F6N4O2 C1=CC(=CC(=C1)C(F)(F)F)C(=NNC(=O)NC2=CC=C(C=C2)OC(F)(F)F)CC3=CC=C(C=C3)C#N InChI=1S/C24H16F6N4O2/c25-23(26,27)18-3-1-2-17(13-18)21(12-15-4-6-16(14-31)7-5-15)33-34-22(35)32-19-8-10-20(11-9-19)36-24(28,29)30/h1-11,13H,12H2,(H2,32,34,35)/b33-21+ organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is identical to the substance Metaflumizone 604-167-6 139968-49-3 1-[(E)-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]amino]-3-[4-(trifluoromethoxy)phenyl]urea Metaflumizone (sum of E- and Z- isomers) C24H16F6N4O2 C1=CC(=CC(=C1)C(F)(F)F)C(=NNC(=O)NC2=CC=C(C=C2)OC(F)(F)F)CC3=CC=C(C=C3)C#N InChI=1S/C24H16F6N4O2/c25-23(26,27)18-3-1-2-17(13-18)21(12-15-4-6-16(14-31)7-5-15)33-34-22(35)32-19-8-10-20(11-9-19)36-24(28,29)30/h1-11,13H,12H2,(H2,32,34,35)/b33-21+ organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is identical to the substance Metaflumizone 604-167-6 139968-49-3 1-[(E)-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]amino]-3-[4-(trifluoromethoxy)phenyl]urea Metaflumizone (sum of E- and Z- isomers) C24H16F6N4O2 C1=CC(=CC(=C1)C(F)(F)F)C(=NNC(=O)NC2=CC=C(C=C2)OC(F)(F)F)CC3=CC=C(C=C3)C#N InChI=1S/C24H16F6N4O2/c25-23(26,27)18-3-1-2-17(13-18)21(12-15-4-6-16(14-31)7-5-15)33-34-22(35)32-19-8-10-20(11-9-19)36-24(28,29)30/h1-11,13H,12H2,(H2,32,34,35)/b33-21+ organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is identical to the substance Metaflumizone 604-167-6 139968-49-3 1-[(E)-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]amino]-3-[4-(trifluoromethoxy)phenyl]urea Metaflumizone (sum of E- and Z- isomers) C24H16F6N4O2 C1=CC(=CC(=C1)C(F)(F)F)C(=NNC(=O)NC2=CC=C(C=C2)OC(F)(F)F)CC3=CC=C(C=C3)C#N InChI=1S/C24H16F6N4O2/c25-23(26,27)18-3-1-2-17(13-18)21(12-15-4-6-16(14-31)7-5-15)33-34-22(35)32-19-8-10-20(11-9-19)36-24(28,29)30/h1-11,13H,12H2,(H2,32,34,35)/b33-21+ organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Positive RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is identical to the substance Metaflumizone 604-167-6 139968-49-3 1-[(E)-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]amino]-3-[4-(trifluoromethoxy)phenyl]urea Metaflumizone (sum of E- and Z- isomers) C24H16F6N4O2 C1=CC(=CC(=C1)C(F)(F)F)C(=NNC(=O)NC2=CC=C(C=C2)OC(F)(F)F)CC3=CC=C(C=C3)C#N InChI=1S/C24H16F6N4O2/c25-23(26,27)18-3-1-2-17(13-18)21(12-15-4-6-16(14-31)7-5-15)33-34-22(35)32-19-8-10-20(11-9-19)36-24(28,29)30/h1-11,13H,12H2,(H2,32,34,35)/b33-21+ organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is identical to the substance Metaflumizone 604-167-6 139968-49-3 1-[(E)-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]amino]-3-[4-(trifluoromethoxy)phenyl]urea Metaflumizone (sum of E- and Z- isomers) C24H16F6N4O2 C1=CC(=CC(=C1)C(F)(F)F)C(=NNC(=O)NC2=CC=C(C=C2)OC(F)(F)F)CC3=CC=C(C=C3)C#N InChI=1S/C24H16F6N4O2/c25-23(26,27)18-3-1-2-17(13-18)21(12-15-4-6-16(14-31)7-5-15)33-34-22(35)32-19-8-10-20(11-9-19)36-24(28,29)30/h1-11,13H,12H2,(H2,32,34,35)/b33-21+ organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 5 Male intraperitoneal 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is identical to the substance Metaflumizone 604-167-6 139968-49-3 1-[(E)-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]amino]-3-[4-(trifluoromethoxy)phenyl]urea Metaflumizone (sum of E- and Z- isomers) C24H16F6N4O2 C1=CC(=CC(=C1)C(F)(F)F)C(=NNC(=O)NC2=CC=C(C=C2)OC(F)(F)F)CC3=CC=C(C=C3)C#N InChI=1S/C24H16F6N4O2/c25-23(26,27)18-3-1-2-17(13-18)21(12-15-4-6-16(14-31)7-5-15)33-34-22(35)32-19-8-10-20(11-9-19)36-24(28,29)30/h1-11,13H,12H2,(H2,32,34,35)/b33-21+ organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Wistar 3 Male oral: unspecified 14.0000000000 h yes not applicable Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is identical to the substance Metaflumizone 604-167-6 139968-49-3 1-[(E)-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]amino]-3-[4-(trifluoromethoxy)phenyl]urea Metaflumizone (sum of E- and Z- isomers) C24H16F6N4O2 C1=CC(=CC(=C1)C(F)(F)F)C(=NNC(=O)NC2=CC=C(C=C2)OC(F)(F)F)CC3=CC=C(C=C3)C#N InChI=1S/C24H16F6N4O2/c25-23(26,27)18-3-1-2-17(13-18)21(12-15-4-6-16(14-31)7-5-15)33-34-22(35)32-19-8-10-20(11-9-19)36-24(28,29)30/h1-11,13H,12H2,(H2,32,34,35)/b33-21+ organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Wistar 3 Male oral: unspecified 3.0000000000 h yes not applicable Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is part of a group assessment Z-isomer of metaflumizone 604-167-6 139968-49-3 1-[(Z)-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]amino]-3-[4-(trifluoromethoxy)phenyl]urea Not in list C24H16F6N4O2 C1=CC(=CC(=C1)C(F)(F)F)C(=NNC(=O)NC2=CC=C(C=C2)OC(F)(F)F)CC3=CC=C(C=C3)C#N InChI=1S/C24H16F6N4O2/c25-23(26,27)18-3-1-2-17(13-18)21(12-15-4-6-16(14-31)7-5-15)33-34-22(35)32-19-8-10-20(11-9-19)36-24(28,29)30/h1-11,13H,12H2,(H2,32,34,35)/b33-21- organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is part of a group assessment Z-isomer of metaflumizone 604-167-6 139968-49-3 1-[(Z)-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]amino]-3-[4-(trifluoromethoxy)phenyl]urea Not in list C24H16F6N4O2 C1=CC(=CC(=C1)C(F)(F)F)C(=NNC(=O)NC2=CC=C(C=C2)OC(F)(F)F)CC3=CC=C(C=C3)C#N InChI=1S/C24H16F6N4O2/c25-23(26,27)18-3-1-2-17(13-18)21(12-15-4-6-16(14-31)7-5-15)33-34-22(35)32-19-8-10-20(11-9-19)36-24(28,29)30/h1-11,13H,12H2,(H2,32,34,35)/b33-21- organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is part of a group assessment Z-isomer of metaflumizone 604-167-6 139968-49-3 1-[(Z)-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]amino]-3-[4-(trifluoromethoxy)phenyl]urea Not in list C24H16F6N4O2 C1=CC(=CC(=C1)C(F)(F)F)C(=NNC(=O)NC2=CC=C(C=C2)OC(F)(F)F)CC3=CC=C(C=C3)C#N InChI=1S/C24H16F6N4O2/c25-23(26,27)18-3-1-2-17(13-18)21(12-15-4-6-16(14-31)7-5-15)33-34-22(35)32-19-8-10-20(11-9-19)36-24(28,29)30/h1-11,13H,12H2,(H2,32,34,35)/b33-21- organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is part of a group assessment Z-isomer of metaflumizone 604-167-6 139968-49-3 1-[(Z)-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]amino]-3-[4-(trifluoromethoxy)phenyl]urea Not in list C24H16F6N4O2 C1=CC(=CC(=C1)C(F)(F)F)C(=NNC(=O)NC2=CC=C(C=C2)OC(F)(F)F)CC3=CC=C(C=C3)C#N InChI=1S/C24H16F6N4O2/c25-23(26,27)18-3-1-2-17(13-18)21(12-15-4-6-16(14-31)7-5-15)33-34-22(35)32-19-8-10-20(11-9-19)36-24(28,29)30/h1-11,13H,12H2,(H2,32,34,35)/b33-21- organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is part of a group assessment Z-isomer of metaflumizone 604-167-6 139968-49-3 1-[(Z)-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]amino]-3-[4-(trifluoromethoxy)phenyl]urea Not in list C24H16F6N4O2 C1=CC(=CC(=C1)C(F)(F)F)C(=NNC(=O)NC2=CC=C(C=C2)OC(F)(F)F)CC3=CC=C(C=C3)C#N InChI=1S/C24H16F6N4O2/c25-23(26,27)18-3-1-2-17(13-18)21(12-15-4-6-16(14-31)7-5-15)33-34-22(35)32-19-8-10-20(11-9-19)36-24(28,29)30/h1-11,13H,12H2,(H2,32,34,35)/b33-21- organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is part of a group assessment Z-isomer of metaflumizone 604-167-6 139968-49-3 1-[(Z)-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]amino]-3-[4-(trifluoromethoxy)phenyl]urea Not in list C24H16F6N4O2 C1=CC(=CC(=C1)C(F)(F)F)C(=NNC(=O)NC2=CC=C(C=C2)OC(F)(F)F)CC3=CC=C(C=C3)C#N InChI=1S/C24H16F6N4O2/c25-23(26,27)18-3-1-2-17(13-18)21(12-15-4-6-16(14-31)7-5-15)33-34-22(35)32-19-8-10-20(11-9-19)36-24(28,29)30/h1-11,13H,12H2,(H2,32,34,35)/b33-21- organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is part of a group assessment Z-isomer of metaflumizone 604-167-6 139968-49-3 1-[(Z)-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]amino]-3-[4-(trifluoromethoxy)phenyl]urea Not in list C24H16F6N4O2 C1=CC(=CC(=C1)C(F)(F)F)C(=NNC(=O)NC2=CC=C(C=C2)OC(F)(F)F)CC3=CC=C(C=C3)C#N InChI=1S/C24H16F6N4O2/c25-23(26,27)18-3-1-2-17(13-18)21(12-15-4-6-16(14-31)7-5-15)33-34-22(35)32-19-8-10-20(11-9-19)36-24(28,29)30/h1-11,13H,12H2,(H2,32,34,35)/b33-21- organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is part of a group assessment Z-isomer of metaflumizone 604-167-6 139968-49-3 1-[(Z)-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]amino]-3-[4-(trifluoromethoxy)phenyl]urea Not in list C24H16F6N4O2 C1=CC(=CC(=C1)C(F)(F)F)C(=NNC(=O)NC2=CC=C(C=C2)OC(F)(F)F)CC3=CC=C(C=C3)C#N InChI=1S/C24H16F6N4O2/c25-23(26,27)18-3-1-2-17(13-18)21(12-15-4-6-16(14-31)7-5-15)33-34-22(35)32-19-8-10-20(11-9-19)36-24(28,29)30/h1-11,13H,12H2,(H2,32,34,35)/b33-21- organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is part of a group assessment Z-isomer of metaflumizone 604-167-6 139968-49-3 1-[(Z)-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]amino]-3-[4-(trifluoromethoxy)phenyl]urea Not in list C24H16F6N4O2 C1=CC(=CC(=C1)C(F)(F)F)C(=NNC(=O)NC2=CC=C(C=C2)OC(F)(F)F)CC3=CC=C(C=C3)C#N InChI=1S/C24H16F6N4O2/c25-23(26,27)18-3-1-2-17(13-18)21(12-15-4-6-16(14-31)7-5-15)33-34-22(35)32-19-8-10-20(11-9-19)36-24(28,29)30/h1-11,13H,12H2,(H2,32,34,35)/b33-21- organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is part of a group assessment Z-isomer of metaflumizone 604-167-6 139968-49-3 1-[(Z)-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]amino]-3-[4-(trifluoromethoxy)phenyl]urea Not in list C24H16F6N4O2 C1=CC(=CC(=C1)C(F)(F)F)C(=NNC(=O)NC2=CC=C(C=C2)OC(F)(F)F)CC3=CC=C(C=C3)C#N InChI=1S/C24H16F6N4O2/c25-23(26,27)18-3-1-2-17(13-18)21(12-15-4-6-16(14-31)7-5-15)33-34-22(35)32-19-8-10-20(11-9-19)36-24(28,29)30/h1-11,13H,12H2,(H2,32,34,35)/b33-21- organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is a metabolite of the substance 4-{(5RS)-5-hydroxy-3-oxo-4-[4-(trifluoromethoxy)phenyl]-6-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1,2,4-triazin-5-yl}benzonitrile 4-{5-hydroxy-3-oxo-4-[4-(trifluoromethoxy)phenyl]-6-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1,2,4-triazin-5-yl}benzonitrile Not in list C25H17F5N4O3 CC(F)(F)Oc1ccc(cc1)N3C(=O)NN=C(c2cc(ccc2)C(F)(F)F)C3(O)c4ccc(C#N)cc4 InChI=1/C25H17F5N4O3/c1-23(26,27)37-20-11-9-19(10-12-20)34-22(35)33-32-21(16-3-2-4-18(13-16)25(28,29)30)24(34,36)17-7-5-15(14-31)6-8-17/h2-13,36H,1H3,(H,33,35) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is a metabolite of the substance 4-{(5RS)-5-hydroxy-3-oxo-4-[4-(trifluoromethoxy)phenyl]-6-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1,2,4-triazin-5-yl}benzonitrile 4-{5-hydroxy-3-oxo-4-[4-(trifluoromethoxy)phenyl]-6-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1,2,4-triazin-5-yl}benzonitrile Not in list C25H17F5N4O3 CC(F)(F)Oc1ccc(cc1)N3C(=O)NN=C(c2cc(ccc2)C(F)(F)F)C3(O)c4ccc(C#N)cc4 InChI=1/C25H17F5N4O3/c1-23(26,27)37-20-11-9-19(10-12-20)34-22(35)33-32-21(16-3-2-4-18(13-16)25(28,29)30)24(34,36)17-7-5-15(14-31)6-8-17/h2-13,36H,1H3,(H,33,35) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is a metabolite of the substance 4-{(5RS)-5-hydroxy-3-oxo-4-[4-(trifluoromethoxy)phenyl]-6-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1,2,4-triazin-5-yl}benzonitrile 4-{5-hydroxy-3-oxo-4-[4-(trifluoromethoxy)phenyl]-6-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1,2,4-triazin-5-yl}benzonitrile Not in list C25H17F5N4O3 CC(F)(F)Oc1ccc(cc1)N3C(=O)NN=C(c2cc(ccc2)C(F)(F)F)C3(O)c4ccc(C#N)cc4 InChI=1/C25H17F5N4O3/c1-23(26,27)37-20-11-9-19(10-12-20)34-22(35)33-32-21(16-3-2-4-18(13-16)25(28,29)30)24(34,36)17-7-5-15(14-31)6-8-17/h2-13,36H,1H3,(H,33,35) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is a metabolite of the substance 4-{(5RS)-5-hydroxy-3-oxo-4-[4-(trifluoromethoxy)phenyl]-6-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1,2,4-triazin-5-yl}benzonitrile 4-{5-hydroxy-3-oxo-4-[4-(trifluoromethoxy)phenyl]-6-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1,2,4-triazin-5-yl}benzonitrile Not in list C25H17F5N4O3 CC(F)(F)Oc1ccc(cc1)N3C(=O)NN=C(c2cc(ccc2)C(F)(F)F)C3(O)c4ccc(C#N)cc4 InChI=1/C25H17F5N4O3/c1-23(26,27)37-20-11-9-19(10-12-20)34-22(35)33-32-21(16-3-2-4-18(13-16)25(28,29)30)24(34,36)17-7-5-15(14-31)6-8-17/h2-13,36H,1H3,(H,33,35) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is a metabolite of the substance 4-{(5RS)-5-hydroxy-3-oxo-4-[4-(trifluoromethoxy)phenyl]-6-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1,2,4-triazin-5-yl}benzonitrile 4-{5-hydroxy-3-oxo-4-[4-(trifluoromethoxy)phenyl]-6-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1,2,4-triazin-5-yl}benzonitrile Not in list C25H17F5N4O3 CC(F)(F)Oc1ccc(cc1)N3C(=O)NN=C(c2cc(ccc2)C(F)(F)F)C3(O)c4ccc(C#N)cc4 InChI=1/C25H17F5N4O3/c1-23(26,27)37-20-11-9-19(10-12-20)34-22(35)33-32-21(16-3-2-4-18(13-16)25(28,29)30)24(34,36)17-7-5-15(14-31)6-8-17/h2-13,36H,1H3,(H,33,35) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is a metabolite of the substance 4-{(5RS)-5-hydroxy-3-oxo-4-[4-(trifluoromethoxy)phenyl]-6-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1,2,4-triazin-5-yl}benzonitrile 4-{5-hydroxy-3-oxo-4-[4-(trifluoromethoxy)phenyl]-6-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1,2,4-triazin-5-yl}benzonitrile Not in list C25H17F5N4O3 CC(F)(F)Oc1ccc(cc1)N3C(=O)NN=C(c2cc(ccc2)C(F)(F)F)C3(O)c4ccc(C#N)cc4 InChI=1/C25H17F5N4O3/c1-23(26,27)37-20-11-9-19(10-12-20)34-22(35)33-32-21(16-3-2-4-18(13-16)25(28,29)30)24(34,36)17-7-5-15(14-31)6-8-17/h2-13,36H,1H3,(H,33,35) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is a metabolite of the substance 4-{(5RS)-5-hydroxy-3-oxo-4-[4-(trifluoromethoxy)phenyl]-6-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1,2,4-triazin-5-yl}benzonitrile 4-{5-hydroxy-3-oxo-4-[4-(trifluoromethoxy)phenyl]-6-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1,2,4-triazin-5-yl}benzonitrile Not in list C25H17F5N4O3 CC(F)(F)Oc1ccc(cc1)N3C(=O)NN=C(c2cc(ccc2)C(F)(F)F)C3(O)c4ccc(C#N)cc4 InChI=1/C25H17F5N4O3/c1-23(26,27)37-20-11-9-19(10-12-20)34-22(35)33-32-21(16-3-2-4-18(13-16)25(28,29)30)24(34,36)17-7-5-15(14-31)6-8-17/h2-13,36H,1H3,(H,33,35) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is a metabolite of the substance 4-{(5RS)-5-hydroxy-3-oxo-4-[4-(trifluoromethoxy)phenyl]-6-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1,2,4-triazin-5-yl}benzonitrile 4-{5-hydroxy-3-oxo-4-[4-(trifluoromethoxy)phenyl]-6-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1,2,4-triazin-5-yl}benzonitrile Not in list C25H17F5N4O3 CC(F)(F)Oc1ccc(cc1)N3C(=O)NN=C(c2cc(ccc2)C(F)(F)F)C3(O)c4ccc(C#N)cc4 InChI=1/C25H17F5N4O3/c1-23(26,27)37-20-11-9-19(10-12-20)34-22(35)33-32-21(16-3-2-4-18(13-16)25(28,29)30)24(34,36)17-7-5-15(14-31)6-8-17/h2-13,36H,1H3,(H,33,35) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is a metabolite of the substance 4-{(5RS)-5-hydroxy-3-oxo-4-[4-(trifluoromethoxy)phenyl]-6-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1,2,4-triazin-5-yl}benzonitrile 4-{5-hydroxy-3-oxo-4-[4-(trifluoromethoxy)phenyl]-6-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1,2,4-triazin-5-yl}benzonitrile Not in list C25H17F5N4O3 CC(F)(F)Oc1ccc(cc1)N3C(=O)NN=C(c2cc(ccc2)C(F)(F)F)C3(O)c4ccc(C#N)cc4 InChI=1/C25H17F5N4O3/c1-23(26,27)37-20-11-9-19(10-12-20)34-22(35)33-32-21(16-3-2-4-18(13-16)25(28,29)30)24(34,36)17-7-5-15(14-31)6-8-17/h2-13,36H,1H3,(H,33,35) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is a metabolite of the substance 4-{(5RS)-5-hydroxy-3-oxo-4-[4-(trifluoromethoxy)phenyl]-6-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1,2,4-triazin-5-yl}benzonitrile 4-{5-hydroxy-3-oxo-4-[4-(trifluoromethoxy)phenyl]-6-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1,2,4-triazin-5-yl}benzonitrile Not in list C25H17F5N4O3 CC(F)(F)Oc1ccc(cc1)N3C(=O)NN=C(c2cc(ccc2)C(F)(F)F)C3(O)c4ccc(C#N)cc4 InChI=1/C25H17F5N4O3/c1-23(26,27)37-20-11-9-19(10-12-20)34-22(35)33-32-21(16-3-2-4-18(13-16)25(28,29)30)24(34,36)17-7-5-15(14-31)6-8-17/h2-13,36H,1H3,(H,33,35) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is a metabolite of the substance 4-{(5RS)-5-hydroxy-3-oxo-4-[4-(trifluoromethoxy)phenyl]-6-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1,2,4-triazin-5-yl}benzonitrile 4-{5-hydroxy-3-oxo-4-[4-(trifluoromethoxy)phenyl]-6-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1,2,4-triazin-5-yl}benzonitrile Not in list C25H17F5N4O3 CC(F)(F)Oc1ccc(cc1)N3C(=O)NN=C(c2cc(ccc2)C(F)(F)F)C3(O)c4ccc(C#N)cc4 InChI=1/C25H17F5N4O3/c1-23(26,27)37-20-11-9-19(10-12-20)34-22(35)33-32-21(16-3-2-4-18(13-16)25(28,29)30)24(34,36)17-7-5-15(14-31)6-8-17/h2-13,36H,1H3,(H,33,35) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is a metabolite of the substance 4-{(5RS)-5-hydroxy-3-oxo-4-[4-(trifluoromethoxy)phenyl]-6-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1,2,4-triazin-5-yl}benzonitrile 4-{5-hydroxy-3-oxo-4-[4-(trifluoromethoxy)phenyl]-6-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1,2,4-triazin-5-yl}benzonitrile Not in list C25H17F5N4O3 CC(F)(F)Oc1ccc(cc1)N3C(=O)NN=C(c2cc(ccc2)C(F)(F)F)C3(O)c4ccc(C#N)cc4 InChI=1/C25H17F5N4O3/c1-23(26,27)37-20-11-9-19(10-12-20)34-22(35)33-32-21(16-3-2-4-18(13-16)25(28,29)30)24(34,36)17-7-5-15(14-31)6-8-17/h2-13,36H,1H3,(H,33,35) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is a metabolite of the substance 4-{(5RS)-5-hydroxy-3-oxo-4-[4-(trifluoromethoxy)phenyl]-6-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1,2,4-triazin-5-yl}benzonitrile 4-{5-hydroxy-3-oxo-4-[4-(trifluoromethoxy)phenyl]-6-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1,2,4-triazin-5-yl}benzonitrile Not in list C25H17F5N4O3 CC(F)(F)Oc1ccc(cc1)N3C(=O)NN=C(c2cc(ccc2)C(F)(F)F)C3(O)c4ccc(C#N)cc4 InChI=1/C25H17F5N4O3/c1-23(26,27)37-20-11-9-19(10-12-20)34-22(35)33-32-21(16-3-2-4-18(13-16)25(28,29)30)24(34,36)17-7-5-15(14-31)6-8-17/h2-13,36H,1H3,(H,33,35) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is a metabolite of the substance 4-{(5RS)-5-hydroxy-3-oxo-4-[4-(trifluoromethoxy)phenyl]-6-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1,2,4-triazin-5-yl}benzonitrile 4-{5-hydroxy-3-oxo-4-[4-(trifluoromethoxy)phenyl]-6-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1,2,4-triazin-5-yl}benzonitrile Not in list C25H17F5N4O3 CC(F)(F)Oc1ccc(cc1)N3C(=O)NN=C(c2cc(ccc2)C(F)(F)F)C3(O)c4ccc(C#N)cc4 InChI=1/C25H17F5N4O3/c1-23(26,27)37-20-11-9-19(10-12-20)34-22(35)33-32-21(16-3-2-4-18(13-16)25(28,29)30)24(34,36)17-7-5-15(14-31)6-8-17/h2-13,36H,1H3,(H,33,35) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Positive RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is a metabolite of the substance 4-{(5RS)-5-hydroxy-3-oxo-4-[4-(trifluoromethoxy)phenyl]-6-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1,2,4-triazin-5-yl}benzonitrile 4-{5-hydroxy-3-oxo-4-[4-(trifluoromethoxy)phenyl]-6-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1,2,4-triazin-5-yl}benzonitrile Not in list C25H17F5N4O3 CC(F)(F)Oc1ccc(cc1)N3C(=O)NN=C(c2cc(ccc2)C(F)(F)F)C3(O)c4ccc(C#N)cc4 InChI=1/C25H17F5N4O3/c1-23(26,27)37-20-11-9-19(10-12-20)34-22(35)33-32-21(16-3-2-4-18(13-16)25(28,29)30)24(34,36)17-7-5-15(14-31)6-8-17/h2-13,36H,1H3,(H,33,35) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 5 Male oral: gavage 24.0000000000 h yes not applicable Negative no evidence RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is a metabolite of the substance 3-(trifluoromethyl)benzoic acid 207-230-2 454-92-2 3-(trifluoromethyl)benzoic acid Not in list C8H5F3O2 FC(F)(F)c1cccc(c1)C(=O)O InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is a metabolite of the substance 3-(trifluoromethyl)benzoic acid 207-230-2 454-92-2 3-(trifluoromethyl)benzoic acid Not in list C8H5F3O2 FC(F)(F)c1cccc(c1)C(=O)O InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is a metabolite of the substance 3-(trifluoromethyl)benzoic acid 207-230-2 454-92-2 3-(trifluoromethyl)benzoic acid Not in list C8H5F3O2 FC(F)(F)c1cccc(c1)C(=O)O InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is a metabolite of the substance 3-(trifluoromethyl)benzoic acid 207-230-2 454-92-2 3-(trifluoromethyl)benzoic acid Not in list C8H5F3O2 FC(F)(F)c1cccc(c1)C(=O)O InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is a metabolite of the substance 3-(trifluoromethyl)benzoic acid 207-230-2 454-92-2 3-(trifluoromethyl)benzoic acid Not in list C8H5F3O2 FC(F)(F)c1cccc(c1)C(=O)O InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is a metabolite of the substance 3-(trifluoromethyl)benzoic acid 207-230-2 454-92-2 3-(trifluoromethyl)benzoic acid Not in list C8H5F3O2 FC(F)(F)c1cccc(c1)C(=O)O InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is a metabolite of the substance 3-(trifluoromethyl)benzoic acid 207-230-2 454-92-2 3-(trifluoromethyl)benzoic acid Not in list C8H5F3O2 FC(F)(F)c1cccc(c1)C(=O)O InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is a metabolite of the substance 3-(trifluoromethyl)benzoic acid 207-230-2 454-92-2 3-(trifluoromethyl)benzoic acid Not in list C8H5F3O2 FC(F)(F)c1cccc(c1)C(=O)O InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is a metabolite of the substance 3-(trifluoromethyl)benzoic acid 207-230-2 454-92-2 3-(trifluoromethyl)benzoic acid Not in list C8H5F3O2 FC(F)(F)c1cccc(c1)C(=O)O InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is a metabolite of the substance 3-(trifluoromethyl)benzoic acid 207-230-2 454-92-2 3-(trifluoromethyl)benzoic acid Not in list C8H5F3O2 FC(F)(F)c1cccc(c1)C(=O)O InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is a metabolite of the substance 3-(trifluoromethyl)benzoic acid 207-230-2 454-92-2 3-(trifluoromethyl)benzoic acid Not in list C8H5F3O2 FC(F)(F)c1cccc(c1)C(=O)O InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is a metabolite of the substance 3-(trifluoromethyl)benzoic acid 207-230-2 454-92-2 3-(trifluoromethyl)benzoic acid Not in list C8H5F3O2 FC(F)(F)c1cccc(c1)C(=O)O InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is a metabolite of the substance 3-(trifluoromethyl)benzoic acid 207-230-2 454-92-2 3-(trifluoromethyl)benzoic acid Not in list C8H5F3O2 FC(F)(F)c1cccc(c1)C(=O)O InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is a metabolite of the substance 3-(trifluoromethyl)benzoic acid 207-230-2 454-92-2 3-(trifluoromethyl)benzoic acid Not in list C8H5F3O2 FC(F)(F)c1cccc(c1)C(=O)O InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is a metabolite of the substance 4-{2-oxo-2-[3-(trifluoromethyl)phenyl]ethyl}benzonitrile 4-{2-oxo-2-[3-(trifluoromethyl)phenyl]ethyl}benzonitrile Not in list C16H10F3NO FC(F)(F)c1cccc(c1)C(=O)Cc2ccc(C#N)cc2 InChI=1/C16H10F3NO/c17-16(18,19)14-3-1-2-13(9-14)15(21)8-11-4-6-12(10-20)7-5-11/h1-7,9H,8H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is a metabolite of the substance 4-{2-oxo-2-[3-(trifluoromethyl)phenyl]ethyl}benzonitrile 4-{2-oxo-2-[3-(trifluoromethyl)phenyl]ethyl}benzonitrile Not in list C16H10F3NO FC(F)(F)c1cccc(c1)C(=O)Cc2ccc(C#N)cc2 InChI=1/C16H10F3NO/c17-16(18,19)14-3-1-2-13(9-14)15(21)8-11-4-6-12(10-20)7-5-11/h1-7,9H,8H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is a metabolite of the substance 4-{2-oxo-2-[3-(trifluoromethyl)phenyl]ethyl}benzonitrile 4-{2-oxo-2-[3-(trifluoromethyl)phenyl]ethyl}benzonitrile Not in list C16H10F3NO FC(F)(F)c1cccc(c1)C(=O)Cc2ccc(C#N)cc2 InChI=1/C16H10F3NO/c17-16(18,19)14-3-1-2-13(9-14)15(21)8-11-4-6-12(10-20)7-5-11/h1-7,9H,8H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) Other Not reported yes with Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is a metabolite of the substance 4-{2-oxo-2-[3-(trifluoromethyl)phenyl]ethyl}benzonitrile 4-{2-oxo-2-[3-(trifluoromethyl)phenyl]ethyl}benzonitrile Not in list C16H10F3NO FC(F)(F)c1cccc(c1)C(=O)Cc2ccc(C#N)cc2 InChI=1/C16H10F3NO/c17-16(18,19)14-3-1-2-13(9-14)15(21)8-11-4-6-12(10-20)7-5-11/h1-7,9H,8H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) Other Not reported yes without Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is a metabolite of the substance 4-cyanobenzoic acid 210-606-9 4-cyanobenzoic acid Not in list C8H5NO2 C1=CC(=CC=C1C#N)C(=O)O InChI=1S/C8H5NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h1-4H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is a metabolite of the substance 4-cyanobenzoic acid 210-606-9 4-cyanobenzoic acid Not in list C8H5NO2 C1=CC(=CC=C1C#N)C(=O)O InChI=1S/C8H5NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h1-4H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is a metabolite of the substance 4-cyanobenzoic acid 210-606-9 4-cyanobenzoic acid Not in list C8H5NO2 C1=CC(=CC=C1C#N)C(=O)O InChI=1S/C8H5NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h1-4H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is a metabolite of the substance 4-cyanobenzoic acid 210-606-9 4-cyanobenzoic acid Not in list C8H5NO2 C1=CC(=CC=C1C#N)C(=O)O InChI=1S/C8H5NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h1-4H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is a metabolite of the substance 4-cyanobenzoic acid 210-606-9 4-cyanobenzoic acid Not in list C8H5NO2 C1=CC(=CC=C1C#N)C(=O)O InChI=1S/C8H5NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h1-4H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is a metabolite of the substance 4-cyanobenzoic acid 210-606-9 4-cyanobenzoic acid Not in list C8H5NO2 C1=CC(=CC=C1C#N)C(=O)O InChI=1S/C8H5NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h1-4H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is a metabolite of the substance 4-cyanobenzoic acid 210-606-9 4-cyanobenzoic acid Not in list C8H5NO2 C1=CC(=CC=C1C#N)C(=O)O InChI=1S/C8H5NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h1-4H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is a metabolite of the substance 4-cyanobenzoic acid 210-606-9 4-cyanobenzoic acid Not in list C8H5NO2 C1=CC(=CC=C1C#N)C(=O)O InChI=1S/C8H5NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h1-4H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is a metabolite of the substance 4-cyanobenzoic acid 210-606-9 4-cyanobenzoic acid Not in list C8H5NO2 C1=CC(=CC=C1C#N)C(=O)O InChI=1S/C8H5NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h1-4H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is a metabolite of the substance 4-cyanobenzoic acid 210-606-9 4-cyanobenzoic acid Not in list C8H5NO2 C1=CC(=CC=C1C#N)C(=O)O InChI=1S/C8H5NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h1-4H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is a metabolite of the substance 4-cyanobenzoic acid 210-606-9 4-cyanobenzoic acid Not in list C8H5NO2 C1=CC(=CC=C1C#N)C(=O)O InChI=1S/C8H5NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h1-4H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is a metabolite of the substance 4-cyanobenzoic acid 210-606-9 4-cyanobenzoic acid Not in list C8H5NO2 C1=CC(=CC=C1C#N)C(=O)O InChI=1S/C8H5NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h1-4H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is a metabolite of the substance 4-cyanobenzoic acid 210-606-9 4-cyanobenzoic acid Not in list C8H5NO2 C1=CC(=CC=C1C#N)C(=O)O InChI=1S/C8H5NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h1-4H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 5 Male oral: gavage 24.0000000000 h yes not applicable Negative indirect evidence-systemic toxicity RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Metaflumizone 604-167-6 139968-49-3 single chemical entity Component is a metabolite of the substance 4-cyanobenzoic acid 210-606-9 4-cyanobenzoic acid Not in list C8H5NO2 C1=CC(=CC=C1C#N)C(=O)O InChI=1S/C8H5NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h1-4H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 5 Male oral: gavage 48.0000000000 h yes not applicable Negative indirect evidence-systemic toxicity RMS: The United Kingdom Metaflumizone 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone. 03Oct2013 2013 doi:10.2903/j.efsa.2013.3373
+Pyroxsulam 422556-08-9 single chemical entity Component is identical to the substance Pyroxsulam 422556-08-9 N-(5,7-dimethoxy-[1,2,4]triazolo[1,5-alpha]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide Pyroxsulam C14H13F3N6O5S COC1=CC(=NC2=NC(=NN12)NS(=O)(=O)C3=C(C=CN=C3OC)C(F)(F)F)OC InChI=1S/C14H13F3N6O5S/c1-26-8-6-9(27-2)23-13(19-8)20-12(21-23)22-29(24,25)10-7(14(15,16)17)4-5-18-11(10)28-3/h4-6H,1-3H3,(H,21,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The United Kingdom Pyroxsulam 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam. 30Apr2013 2013 doi:10.2903/j.efsa.2013.3182
+Pyroxsulam 422556-08-9 single chemical entity Component is identical to the substance Pyroxsulam 422556-08-9 N-(5,7-dimethoxy-[1,2,4]triazolo[1,5-alpha]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide Pyroxsulam C14H13F3N6O5S COC1=CC(=NC2=NC(=NN12)NS(=O)(=O)C3=C(C=CN=C3OC)C(F)(F)F)OC InChI=1S/C14H13F3N6O5S/c1-26-8-6-9(27-2)23-13(19-8)20-12(21-23)22-29(24,25)10-7(14(15,16)17)4-5-18-11(10)28-3/h4-6H,1-3H3,(H,21,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The United Kingdom Pyroxsulam 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam. 30Apr2013 2013 doi:10.2903/j.efsa.2013.3182
+Pyroxsulam 422556-08-9 single chemical entity Component is identical to the substance Pyroxsulam 422556-08-9 N-(5,7-dimethoxy-[1,2,4]triazolo[1,5-alpha]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide Pyroxsulam C14H13F3N6O5S COC1=CC(=NC2=NC(=NN12)NS(=O)(=O)C3=C(C=CN=C3OC)C(F)(F)F)OC InChI=1S/C14H13F3N6O5S/c1-26-8-6-9(27-2)23-13(19-8)20-12(21-23)22-29(24,25)10-7(14(15,16)17)4-5-18-11(10)28-3/h4-6H,1-3H3,(H,21,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The United Kingdom Pyroxsulam 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam. 30Apr2013 2013 doi:10.2903/j.efsa.2013.3182
+Pyroxsulam 422556-08-9 single chemical entity Component is identical to the substance Pyroxsulam 422556-08-9 N-(5,7-dimethoxy-[1,2,4]triazolo[1,5-alpha]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide Pyroxsulam C14H13F3N6O5S COC1=CC(=NC2=NC(=NN12)NS(=O)(=O)C3=C(C=CN=C3OC)C(F)(F)F)OC InChI=1S/C14H13F3N6O5S/c1-26-8-6-9(27-2)23-13(19-8)20-12(21-23)22-29(24,25)10-7(14(15,16)17)4-5-18-11(10)28-3/h4-6H,1-3H3,(H,21,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The United Kingdom Pyroxsulam 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam. 30Apr2013 2013 doi:10.2903/j.efsa.2013.3182
+Pyroxsulam 422556-08-9 single chemical entity Component is identical to the substance Pyroxsulam 422556-08-9 N-(5,7-dimethoxy-[1,2,4]triazolo[1,5-alpha]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide Pyroxsulam C14H13F3N6O5S COC1=CC(=NC2=NC(=NN12)NS(=O)(=O)C3=C(C=CN=C3OC)C(F)(F)F)OC InChI=1S/C14H13F3N6O5S/c1-26-8-6-9(27-2)23-13(19-8)20-12(21-23)22-29(24,25)10-7(14(15,16)17)4-5-18-11(10)28-3/h4-6H,1-3H3,(H,21,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: The United Kingdom Pyroxsulam 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam. 30Apr2013 2013 doi:10.2903/j.efsa.2013.3182
+Pyroxsulam 422556-08-9 single chemical entity Component is identical to the substance Pyroxsulam 422556-08-9 N-(5,7-dimethoxy-[1,2,4]triazolo[1,5-alpha]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide Pyroxsulam C14H13F3N6O5S COC1=CC(=NC2=NC(=NN12)NS(=O)(=O)C3=C(C=CN=C3OC)C(F)(F)F)OC InChI=1S/C14H13F3N6O5S/c1-26-8-6-9(27-2)23-13(19-8)20-12(21-23)22-29(24,25)10-7(14(15,16)17)4-5-18-11(10)28-3/h4-6H,1-3H3,(H,21,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: The United Kingdom Pyroxsulam 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam. 30Apr2013 2013 doi:10.2903/j.efsa.2013.3182
+Pyroxsulam 422556-08-9 single chemical entity Component is identical to the substance Pyroxsulam 422556-08-9 N-(5,7-dimethoxy-[1,2,4]triazolo[1,5-alpha]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide Pyroxsulam C14H13F3N6O5S COC1=CC(=NC2=NC(=NN12)NS(=O)(=O)C3=C(C=CN=C3OC)C(F)(F)F)OC InChI=1S/C14H13F3N6O5S/c1-26-8-6-9(27-2)23-13(19-8)20-12(21-23)22-29(24,25)10-7(14(15,16)17)4-5-18-11(10)28-3/h4-6H,1-3H3,(H,21,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The United Kingdom Pyroxsulam 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam. 30Apr2013 2013 doi:10.2903/j.efsa.2013.3182
+Pyroxsulam 422556-08-9 single chemical entity Component is identical to the substance Pyroxsulam 422556-08-9 N-(5,7-dimethoxy-[1,2,4]triazolo[1,5-alpha]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide Pyroxsulam C14H13F3N6O5S COC1=CC(=NC2=NC(=NN12)NS(=O)(=O)C3=C(C=CN=C3OC)C(F)(F)F)OC InChI=1S/C14H13F3N6O5S/c1-26-8-6-9(27-2)23-13(19-8)20-12(21-23)22-29(24,25)10-7(14(15,16)17)4-5-18-11(10)28-3/h4-6H,1-3H3,(H,21,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The United Kingdom Pyroxsulam 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam. 30Apr2013 2013 doi:10.2903/j.efsa.2013.3182
+Pyroxsulam 422556-08-9 single chemical entity Component is identical to the substance Pyroxsulam 422556-08-9 N-(5,7-dimethoxy-[1,2,4]triazolo[1,5-alpha]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide Pyroxsulam C14H13F3N6O5S COC1=CC(=NC2=NC(=NN12)NS(=O)(=O)C3=C(C=CN=C3OC)C(F)(F)F)OC InChI=1S/C14H13F3N6O5S/c1-26-8-6-9(27-2)23-13(19-8)20-12(21-23)22-29(24,25)10-7(14(15,16)17)4-5-18-11(10)28-3/h4-6H,1-3H3,(H,21,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The United Kingdom Pyroxsulam 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam. 30Apr2013 2013 doi:10.2903/j.efsa.2013.3182
+Pyroxsulam 422556-08-9 single chemical entity Component is identical to the substance Pyroxsulam 422556-08-9 N-(5,7-dimethoxy-[1,2,4]triazolo[1,5-alpha]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide Pyroxsulam C14H13F3N6O5S COC1=CC(=NC2=NC(=NN12)NS(=O)(=O)C3=C(C=CN=C3OC)C(F)(F)F)OC InChI=1S/C14H13F3N6O5S/c1-26-8-6-9(27-2)23-13(19-8)20-12(21-23)22-29(24,25)10-7(14(15,16)17)4-5-18-11(10)28-3/h4-6H,1-3H3,(H,21,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The United Kingdom Pyroxsulam 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam. 30Apr2013 2013 doi:10.2903/j.efsa.2013.3182
+Pyroxsulam 422556-08-9 single chemical entity Component is identical to the substance Pyroxsulam 422556-08-9 N-(5,7-dimethoxy-[1,2,4]triazolo[1,5-alpha]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide Pyroxsulam C14H13F3N6O5S COC1=CC(=NC2=NC(=NN12)NS(=O)(=O)C3=C(C=CN=C3OC)C(F)(F)F)OC InChI=1S/C14H13F3N6O5S/c1-26-8-6-9(27-2)23-13(19-8)20-12(21-23)22-29(24,25)10-7(14(15,16)17)4-5-18-11(10)28-3/h4-6H,1-3H3,(H,21,22) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Rat (as animal) lymphocytes Not reported yes without Negative RMS: The United Kingdom Pyroxsulam 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam. 30Apr2013 2013 doi:10.2903/j.efsa.2013.3182
+Pyroxsulam 422556-08-9 single chemical entity Component is identical to the substance Pyroxsulam 422556-08-9 N-(5,7-dimethoxy-[1,2,4]triazolo[1,5-alpha]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide Pyroxsulam C14H13F3N6O5S COC1=CC(=NC2=NC(=NN12)NS(=O)(=O)C3=C(C=CN=C3OC)C(F)(F)F)OC InChI=1S/C14H13F3N6O5S/c1-26-8-6-9(27-2)23-13(19-8)20-12(21-23)22-29(24,25)10-7(14(15,16)17)4-5-18-11(10)28-3/h4-6H,1-3H3,(H,21,22) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Rat (as animal) lymphocytes Not reported yes with Negative RMS: The United Kingdom Pyroxsulam 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam. 30Apr2013 2013 doi:10.2903/j.efsa.2013.3182
+Pyroxsulam 422556-08-9 single chemical entity Component is identical to the substance Pyroxsulam 422556-08-9 N-(5,7-dimethoxy-[1,2,4]triazolo[1,5-alpha]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide Pyroxsulam C14H13F3N6O5S COC1=CC(=NC2=NC(=NN12)NS(=O)(=O)C3=C(C=CN=C3OC)C(F)(F)F)OC InChI=1S/C14H13F3N6O5S/c1-26-8-6-9(27-2)23-13(19-8)20-12(21-23)22-29(24,25)10-7(14(15,16)17)4-5-18-11(10)28-3/h4-6H,1-3H3,(H,21,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: The United Kingdom Pyroxsulam 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam. 30Apr2013 2013 doi:10.2903/j.efsa.2013.3182
+Pyroxsulam 422556-08-9 single chemical entity Component is identical to the substance Pyroxsulam 422556-08-9 N-(5,7-dimethoxy-[1,2,4]triazolo[1,5-alpha]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide Pyroxsulam C14H13F3N6O5S COC1=CC(=NC2=NC(=NN12)NS(=O)(=O)C3=C(C=CN=C3OC)C(F)(F)F)OC InChI=1S/C14H13F3N6O5S/c1-26-8-6-9(27-2)23-13(19-8)20-12(21-23)22-29(24,25)10-7(14(15,16)17)4-5-18-11(10)28-3/h4-6H,1-3H3,(H,21,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: The United Kingdom Pyroxsulam 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam. 30Apr2013 2013 doi:10.2903/j.efsa.2013.3182
+Pyroxsulam 422556-08-9 single chemical entity Component is identical to the substance Pyroxsulam 422556-08-9 N-(5,7-dimethoxy-[1,2,4]triazolo[1,5-alpha]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide Pyroxsulam C14H13F3N6O5S COC1=CC(=NC2=NC(=NN12)NS(=O)(=O)C3=C(C=CN=C3OC)C(F)(F)F)OC InChI=1S/C14H13F3N6O5S/c1-26-8-6-9(27-2)23-13(19-8)20-12(21-23)22-29(24,25)10-7(14(15,16)17)4-5-18-11(10)28-3/h4-6H,1-3H3,(H,21,22) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 6 Male oral: gavage 24.0000000000 h yes not applicable Negative no evidence RMS: The United Kingdom Pyroxsulam 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam. 30Apr2013 2013 doi:10.2903/j.efsa.2013.3182
+Pyroxsulam 422556-08-9 single chemical entity Component is identical to the substance Pyroxsulam 422556-08-9 N-(5,7-dimethoxy-[1,2,4]triazolo[1,5-alpha]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide Pyroxsulam C14H13F3N6O5S COC1=CC(=NC2=NC(=NN12)NS(=O)(=O)C3=C(C=CN=C3OC)C(F)(F)F)OC InChI=1S/C14H13F3N6O5S/c1-26-8-6-9(27-2)23-13(19-8)20-12(21-23)22-29(24,25)10-7(14(15,16)17)4-5-18-11(10)28-3/h4-6H,1-3H3,(H,21,22) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo Equivalent or similar to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) Yes Acceptable House mouse (as animal) CD-1 6 Male oral: gavage 4.0000000000 h yes not applicable Negative RMS: The United Kingdom Pyroxsulam 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam. 30Apr2013 2013 doi:10.2903/j.efsa.2013.3182
+Pyroxsulam 422556-08-9 single chemical entity Component is identical to the substance Pyroxsulam 422556-08-9 N-(5,7-dimethoxy-[1,2,4]triazolo[1,5-alpha]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide Pyroxsulam C14H13F3N6O5S COC1=CC(=NC2=NC(=NN12)NS(=O)(=O)C3=C(C=CN=C3OC)C(F)(F)F)OC InChI=1S/C14H13F3N6O5S/c1-26-8-6-9(27-2)23-13(19-8)20-12(21-23)22-29(24,25)10-7(14(15,16)17)4-5-18-11(10)28-3/h4-6H,1-3H3,(H,21,22) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo Equivalent or similar to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) Yes Acceptable House mouse (as animal) CD-1 6 Male oral: gavage 14.0000000000 h yes not applicable Negative RMS: The United Kingdom Pyroxsulam 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam. 30Apr2013 2013 doi:10.2903/j.efsa.2013.3182
+Pyroxsulam 422556-08-9 single chemical entity Component is a metabolite of the substance N-(6-chloro-7-hydroxy-5-methoxy [1,2,4] triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl) pyridine -3-sulfonamide N-(6-chloro-7-hydroxy-5-methoxy[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide N-(6-chloro-7-hydroxy-5-methoxy [1,2,4] triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl) pyridine -3-sulfonamide C13H10ClF3N6O5S FC(F)(F)c1ccnc(OC)c1S(=O)(=O)Nc2nc3nc(OC)c(Cl)c(O)n3n2 InChI=1S/C13H10ClF3N6O5S/c1-27-8-6(14)10(24)23-12(19-8)20-11(21-23)22-29(25,26)7-5(13(15,16)17)3-4-18-9(7)28-2/h3-4,24H,1-2H3,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes without Negative RMS: The United Kingdom Pyroxsulam 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam. 30Apr2013 2013 doi:10.2903/j.efsa.2013.3182
+Pyroxsulam 422556-08-9 single chemical entity Component is a metabolite of the substance N-(6-chloro-7-hydroxy-5-methoxy [1,2,4] triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl) pyridine -3-sulfonamide N-(6-chloro-7-hydroxy-5-methoxy[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide N-(6-chloro-7-hydroxy-5-methoxy [1,2,4] triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl) pyridine -3-sulfonamide C13H10ClF3N6O5S FC(F)(F)c1ccnc(OC)c1S(=O)(=O)Nc2nc3nc(OC)c(Cl)c(O)n3n2 InChI=1S/C13H10ClF3N6O5S/c1-27-8-6(14)10(24)23-12(19-8)20-11(21-23)22-29(25,26)7-5(13(15,16)17)3-4-18-9(7)28-2/h3-4,24H,1-2H3,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes with Negative RMS: The United Kingdom Pyroxsulam 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam. 30Apr2013 2013 doi:10.2903/j.efsa.2013.3182
+Pyroxsulam 422556-08-9 single chemical entity Component is a metabolite of the substance N-(6-chloro-7-hydroxy-5-methoxy [1,2,4] triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl) pyridine -3-sulfonamide N-(6-chloro-7-hydroxy-5-methoxy[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide N-(6-chloro-7-hydroxy-5-methoxy [1,2,4] triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl) pyridine -3-sulfonamide C13H10ClF3N6O5S FC(F)(F)c1ccnc(OC)c1S(=O)(=O)Nc2nc3nc(OC)c(Cl)c(O)n3n2 InChI=1S/C13H10ClF3N6O5S/c1-27-8-6(14)10(24)23-12(19-8)20-11(21-23)22-29(25,26)7-5(13(15,16)17)3-4-18-9(7)28-2/h3-4,24H,1-2H3,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The United Kingdom Pyroxsulam 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam. 30Apr2013 2013 doi:10.2903/j.efsa.2013.3182
+Pyroxsulam 422556-08-9 single chemical entity Component is a metabolite of the substance N-(6-chloro-7-hydroxy-5-methoxy [1,2,4] triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl) pyridine -3-sulfonamide N-(6-chloro-7-hydroxy-5-methoxy[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide N-(6-chloro-7-hydroxy-5-methoxy [1,2,4] triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl) pyridine -3-sulfonamide C13H10ClF3N6O5S FC(F)(F)c1ccnc(OC)c1S(=O)(=O)Nc2nc3nc(OC)c(Cl)c(O)n3n2 InChI=1S/C13H10ClF3N6O5S/c1-27-8-6(14)10(24)23-12(19-8)20-11(21-23)22-29(25,26)7-5(13(15,16)17)3-4-18-9(7)28-2/h3-4,24H,1-2H3,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The United Kingdom Pyroxsulam 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam. 30Apr2013 2013 doi:10.2903/j.efsa.2013.3182
+Pyroxsulam 422556-08-9 single chemical entity Component is a metabolite of the substance N-(6-chloro-7-hydroxy-5-methoxy [1,2,4] triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl) pyridine -3-sulfonamide N-(6-chloro-7-hydroxy-5-methoxy[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide N-(6-chloro-7-hydroxy-5-methoxy [1,2,4] triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl) pyridine -3-sulfonamide C13H10ClF3N6O5S FC(F)(F)c1ccnc(OC)c1S(=O)(=O)Nc2nc3nc(OC)c(Cl)c(O)n3n2 InChI=1S/C13H10ClF3N6O5S/c1-27-8-6(14)10(24)23-12(19-8)20-11(21-23)22-29(25,26)7-5(13(15,16)17)3-4-18-9(7)28-2/h3-4,24H,1-2H3,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The United Kingdom Pyroxsulam 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam. 30Apr2013 2013 doi:10.2903/j.efsa.2013.3182
+Pyroxsulam 422556-08-9 single chemical entity Component is a metabolite of the substance N-(6-chloro-7-hydroxy-5-methoxy [1,2,4] triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl) pyridine -3-sulfonamide N-(6-chloro-7-hydroxy-5-methoxy[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide N-(6-chloro-7-hydroxy-5-methoxy [1,2,4] triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl) pyridine -3-sulfonamide C13H10ClF3N6O5S FC(F)(F)c1ccnc(OC)c1S(=O)(=O)Nc2nc3nc(OC)c(Cl)c(O)n3n2 InChI=1S/C13H10ClF3N6O5S/c1-27-8-6(14)10(24)23-12(19-8)20-11(21-23)22-29(25,26)7-5(13(15,16)17)3-4-18-9(7)28-2/h3-4,24H,1-2H3,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The United Kingdom Pyroxsulam 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam. 30Apr2013 2013 doi:10.2903/j.efsa.2013.3182
+Pyroxsulam 422556-08-9 single chemical entity Component is a metabolite of the substance N-(6-chloro-7-hydroxy-5-methoxy [1,2,4] triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl) pyridine -3-sulfonamide N-(6-chloro-7-hydroxy-5-methoxy[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide N-(6-chloro-7-hydroxy-5-methoxy [1,2,4] triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl) pyridine -3-sulfonamide C13H10ClF3N6O5S FC(F)(F)c1ccnc(OC)c1S(=O)(=O)Nc2nc3nc(OC)c(Cl)c(O)n3n2 InChI=1S/C13H10ClF3N6O5S/c1-27-8-6(14)10(24)23-12(19-8)20-11(21-23)22-29(25,26)7-5(13(15,16)17)3-4-18-9(7)28-2/h3-4,24H,1-2H3,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The United Kingdom Pyroxsulam 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam. 30Apr2013 2013 doi:10.2903/j.efsa.2013.3182
+Pyroxsulam 422556-08-9 single chemical entity Component is a metabolite of the substance N-(6-chloro-7-hydroxy-5-methoxy [1,2,4] triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl) pyridine -3-sulfonamide N-(6-chloro-7-hydroxy-5-methoxy[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide N-(6-chloro-7-hydroxy-5-methoxy [1,2,4] triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl) pyridine -3-sulfonamide C13H10ClF3N6O5S FC(F)(F)c1ccnc(OC)c1S(=O)(=O)Nc2nc3nc(OC)c(Cl)c(O)n3n2 InChI=1S/C13H10ClF3N6O5S/c1-27-8-6(14)10(24)23-12(19-8)20-11(21-23)22-29(25,26)7-5(13(15,16)17)3-4-18-9(7)28-2/h3-4,24H,1-2H3,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The United Kingdom Pyroxsulam 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam. 30Apr2013 2013 doi:10.2903/j.efsa.2013.3182
+Pyroxsulam 422556-08-9 single chemical entity Component is a metabolite of the substance N-(6-chloro-7-hydroxy-5-methoxy [1,2,4] triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl) pyridine -3-sulfonamide N-(6-chloro-7-hydroxy-5-methoxy[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide N-(6-chloro-7-hydroxy-5-methoxy [1,2,4] triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl) pyridine -3-sulfonamide C13H10ClF3N6O5S FC(F)(F)c1ccnc(OC)c1S(=O)(=O)Nc2nc3nc(OC)c(Cl)c(O)n3n2 InChI=1S/C13H10ClF3N6O5S/c1-27-8-6(14)10(24)23-12(19-8)20-11(21-23)22-29(25,26)7-5(13(15,16)17)3-4-18-9(7)28-2/h3-4,24H,1-2H3,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The United Kingdom Pyroxsulam 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam. 30Apr2013 2013 doi:10.2903/j.efsa.2013.3182
+Pyroxsulam 422556-08-9 single chemical entity Component is a metabolite of the substance N-(6-chloro-7-hydroxy-5-methoxy [1,2,4] triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl) pyridine -3-sulfonamide N-(6-chloro-7-hydroxy-5-methoxy[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide N-(6-chloro-7-hydroxy-5-methoxy [1,2,4] triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl) pyridine -3-sulfonamide C13H10ClF3N6O5S FC(F)(F)c1ccnc(OC)c1S(=O)(=O)Nc2nc3nc(OC)c(Cl)c(O)n3n2 InChI=1S/C13H10ClF3N6O5S/c1-27-8-6(14)10(24)23-12(19-8)20-11(21-23)22-29(25,26)7-5(13(15,16)17)3-4-18-9(7)28-2/h3-4,24H,1-2H3,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The United Kingdom Pyroxsulam 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam. 30Apr2013 2013 doi:10.2903/j.efsa.2013.3182
+Pyroxsulam 422556-08-9 single chemical entity Component is a metabolite of the substance 2-Methoxy-4-(trifluoromethyl)-3-pyridinesulfonic acid 2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonic acid Not in list C7H6F3NO4S COc1nccc(c1S(=O)(=O)O)C(F)(F)F InChI=1S/C7H6F3NO4S/c1-15-6-5(16(12,13)14)4(2-3-11-6)7(8,9)10/h2-3H,1H3,(H,12,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The United Kingdom Pyroxsulam 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam. 30Apr2013 2013 doi:10.2903/j.efsa.2013.3182
+Pyroxsulam 422556-08-9 single chemical entity Component is a metabolite of the substance 2-Methoxy-4-(trifluoromethyl)-3-pyridinesulfonic acid 2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonic acid Not in list C7H6F3NO4S COc1nccc(c1S(=O)(=O)O)C(F)(F)F InChI=1S/C7H6F3NO4S/c1-15-6-5(16(12,13)14)4(2-3-11-6)7(8,9)10/h2-3H,1H3,(H,12,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The United Kingdom Pyroxsulam 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam. 30Apr2013 2013 doi:10.2903/j.efsa.2013.3182
+Pyroxsulam 422556-08-9 single chemical entity Component is a metabolite of the substance 2-Methoxy-4-(trifluoromethyl)-3-pyridinesulfonic acid 2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonic acid Not in list C7H6F3NO4S COc1nccc(c1S(=O)(=O)O)C(F)(F)F InChI=1S/C7H6F3NO4S/c1-15-6-5(16(12,13)14)4(2-3-11-6)7(8,9)10/h2-3H,1H3,(H,12,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: The United Kingdom Pyroxsulam 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam. 30Apr2013 2013 doi:10.2903/j.efsa.2013.3182
+Pyroxsulam 422556-08-9 single chemical entity Component is a metabolite of the substance 2-Methoxy-4-(trifluoromethyl)-3-pyridinesulfonic acid 2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonic acid Not in list C7H6F3NO4S COc1nccc(c1S(=O)(=O)O)C(F)(F)F InChI=1S/C7H6F3NO4S/c1-15-6-5(16(12,13)14)4(2-3-11-6)7(8,9)10/h2-3H,1H3,(H,12,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: The United Kingdom Pyroxsulam 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam. 30Apr2013 2013 doi:10.2903/j.efsa.2013.3182
+Pyroxsulam 422556-08-9 single chemical entity Component is a metabolite of the substance 2-Methoxy-4-(trifluoromethyl)-3-pyridinesulfonic acid 2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonic acid Not in list C7H6F3NO4S COc1nccc(c1S(=O)(=O)O)C(F)(F)F InChI=1S/C7H6F3NO4S/c1-15-6-5(16(12,13)14)4(2-3-11-6)7(8,9)10/h2-3H,1H3,(H,12,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The United Kingdom Pyroxsulam 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam. 30Apr2013 2013 doi:10.2903/j.efsa.2013.3182
+Pyroxsulam 422556-08-9 single chemical entity Component is a metabolite of the substance 2-Methoxy-4-(trifluoromethyl)-3-pyridinesulfonic acid 2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonic acid Not in list C7H6F3NO4S COc1nccc(c1S(=O)(=O)O)C(F)(F)F InChI=1S/C7H6F3NO4S/c1-15-6-5(16(12,13)14)4(2-3-11-6)7(8,9)10/h2-3H,1H3,(H,12,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The United Kingdom Pyroxsulam 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam. 30Apr2013 2013 doi:10.2903/j.efsa.2013.3182
+Pyroxsulam 422556-08-9 single chemical entity Component is a metabolite of the substance 2-Methoxy-4-(trifluoromethyl)-3-pyridinesulfonic acid 2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonic acid Not in list C7H6F3NO4S COc1nccc(c1S(=O)(=O)O)C(F)(F)F InChI=1S/C7H6F3NO4S/c1-15-6-5(16(12,13)14)4(2-3-11-6)7(8,9)10/h2-3H,1H3,(H,12,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The United Kingdom Pyroxsulam 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam. 30Apr2013 2013 doi:10.2903/j.efsa.2013.3182
+Pyroxsulam 422556-08-9 single chemical entity Component is a metabolite of the substance 2-Methoxy-4-(trifluoromethyl)-3-pyridinesulfonic acid 2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonic acid Not in list C7H6F3NO4S COc1nccc(c1S(=O)(=O)O)C(F)(F)F InChI=1S/C7H6F3NO4S/c1-15-6-5(16(12,13)14)4(2-3-11-6)7(8,9)10/h2-3H,1H3,(H,12,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The United Kingdom Pyroxsulam 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam. 30Apr2013 2013 doi:10.2903/j.efsa.2013.3182
+Pyroxsulam 422556-08-9 single chemical entity Component is a metabolite of the substance 2-Methoxy-4-(trifluoromethyl)-3-pyridinesulfonic acid 2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonic acid Not in list C7H6F3NO4S COc1nccc(c1S(=O)(=O)O)C(F)(F)F InChI=1S/C7H6F3NO4S/c1-15-6-5(16(12,13)14)4(2-3-11-6)7(8,9)10/h2-3H,1H3,(H,12,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The United Kingdom Pyroxsulam 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam. 30Apr2013 2013 doi:10.2903/j.efsa.2013.3182
+Pyroxsulam 422556-08-9 single chemical entity Component is a metabolite of the substance 2-Methoxy-4-(trifluoromethyl)-3-pyridinesulfonic acid 2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonic acid Not in list C7H6F3NO4S COc1nccc(c1S(=O)(=O)O)C(F)(F)F InChI=1S/C7H6F3NO4S/c1-15-6-5(16(12,13)14)4(2-3-11-6)7(8,9)10/h2-3H,1H3,(H,12,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The United Kingdom Pyroxsulam 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam. 30Apr2013 2013 doi:10.2903/j.efsa.2013.3182
+Pyroxsulam 422556-08-9 single chemical entity Component is a metabolite of the substance 2-Methoxy-4-(trifluoromethyl)-3-pyridinesulfonic acid 2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonic acid Not in list C7H6F3NO4S COc1nccc(c1S(=O)(=O)O)C(F)(F)F InChI=1S/C7H6F3NO4S/c1-15-6-5(16(12,13)14)4(2-3-11-6)7(8,9)10/h2-3H,1H3,(H,12,13,14) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Rat (as animal) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Pyroxsulam 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam. 30Apr2013 2013 doi:10.2903/j.efsa.2013.3182
+Pyroxsulam 422556-08-9 single chemical entity Component is a metabolite of the substance 2-Methoxy-4-(trifluoromethyl)-3-pyridinesulfonic acid 2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonic acid Not in list C7H6F3NO4S COc1nccc(c1S(=O)(=O)O)C(F)(F)F InChI=1S/C7H6F3NO4S/c1-15-6-5(16(12,13)14)4(2-3-11-6)7(8,9)10/h2-3H,1H3,(H,12,13,14) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Rat (as animal) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Pyroxsulam 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam. 30Apr2013 2013 doi:10.2903/j.efsa.2013.3182
+Pyroxsulam 422556-08-9 single chemical entity Component is a metabolite of the substance 2-Methoxy-4-(trifluoromethyl)-3-pyridinesulfonic acid 2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonic acid Not in list C7H6F3NO4S COc1nccc(c1S(=O)(=O)O)C(F)(F)F InChI=1S/C7H6F3NO4S/c1-15-6-5(16(12,13)14)4(2-3-11-6)7(8,9)10/h2-3H,1H3,(H,12,13,14) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: The United Kingdom Pyroxsulam 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam. 30Apr2013 2013 doi:10.2903/j.efsa.2013.3182
+Pyroxsulam 422556-08-9 single chemical entity Component is a metabolite of the substance 2-Methoxy-4-(trifluoromethyl)-3-pyridinesulfonic acid 2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonic acid Not in list C7H6F3NO4S COc1nccc(c1S(=O)(=O)O)C(F)(F)F InChI=1S/C7H6F3NO4S/c1-15-6-5(16(12,13)14)4(2-3-11-6)7(8,9)10/h2-3H,1H3,(H,12,13,14) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: The United Kingdom Pyroxsulam 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam. 30Apr2013 2013 doi:10.2903/j.efsa.2013.3182
+Pyroxsulam 422556-08-9 single chemical entity Component is a metabolite of the substance 2-Methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide 2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide 2-Methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide C7H7F3N2O3S COc1nccc(c1S(N)(=O)=O)C(F)(F)F InChI=1S/C7H7F3N2O3S/c1-15-6-5(16(11,13)14)4(2-3-12-6)7(8,9)10/h2-3H,1H3,(H2,11,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The United Kingdom Pyroxsulam 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam. 30Apr2013 2013 doi:10.2903/j.efsa.2013.3182
+Pyroxsulam 422556-08-9 single chemical entity Component is a metabolite of the substance 2-Methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide 2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide 2-Methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide C7H7F3N2O3S COc1nccc(c1S(N)(=O)=O)C(F)(F)F InChI=1S/C7H7F3N2O3S/c1-15-6-5(16(11,13)14)4(2-3-12-6)7(8,9)10/h2-3H,1H3,(H2,11,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: The United Kingdom Pyroxsulam 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam. 30Apr2013 2013 doi:10.2903/j.efsa.2013.3182
+Pyroxsulam 422556-08-9 single chemical entity Component is a metabolite of the substance 2-Methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide 2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide 2-Methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide C7H7F3N2O3S COc1nccc(c1S(N)(=O)=O)C(F)(F)F InChI=1S/C7H7F3N2O3S/c1-15-6-5(16(11,13)14)4(2-3-12-6)7(8,9)10/h2-3H,1H3,(H2,11,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: The United Kingdom Pyroxsulam 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam. 30Apr2013 2013 doi:10.2903/j.efsa.2013.3182
+Pyroxsulam 422556-08-9 single chemical entity Component is a metabolite of the substance 2-Methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide 2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide 2-Methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide C7H7F3N2O3S COc1nccc(c1S(N)(=O)=O)C(F)(F)F InChI=1S/C7H7F3N2O3S/c1-15-6-5(16(11,13)14)4(2-3-12-6)7(8,9)10/h2-3H,1H3,(H2,11,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The United Kingdom Pyroxsulam 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam. 30Apr2013 2013 doi:10.2903/j.efsa.2013.3182
+Pyroxsulam 422556-08-9 single chemical entity Component is a metabolite of the substance 2-Methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide 2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide 2-Methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide C7H7F3N2O3S COc1nccc(c1S(N)(=O)=O)C(F)(F)F InChI=1S/C7H7F3N2O3S/c1-15-6-5(16(11,13)14)4(2-3-12-6)7(8,9)10/h2-3H,1H3,(H2,11,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The United Kingdom Pyroxsulam 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam. 30Apr2013 2013 doi:10.2903/j.efsa.2013.3182
+Pyroxsulam 422556-08-9 single chemical entity Component is a metabolite of the substance 2-Methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide 2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide 2-Methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide C7H7F3N2O3S COc1nccc(c1S(N)(=O)=O)C(F)(F)F InChI=1S/C7H7F3N2O3S/c1-15-6-5(16(11,13)14)4(2-3-12-6)7(8,9)10/h2-3H,1H3,(H2,11,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The United Kingdom Pyroxsulam 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam. 30Apr2013 2013 doi:10.2903/j.efsa.2013.3182
+Pyroxsulam 422556-08-9 single chemical entity Component is a metabolite of the substance 2-Methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide 2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide 2-Methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide C7H7F3N2O3S COc1nccc(c1S(N)(=O)=O)C(F)(F)F InChI=1S/C7H7F3N2O3S/c1-15-6-5(16(11,13)14)4(2-3-12-6)7(8,9)10/h2-3H,1H3,(H2,11,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The United Kingdom Pyroxsulam 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam. 30Apr2013 2013 doi:10.2903/j.efsa.2013.3182
+Pyroxsulam 422556-08-9 single chemical entity Component is a metabolite of the substance 2-Methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide 2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide 2-Methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide C7H7F3N2O3S COc1nccc(c1S(N)(=O)=O)C(F)(F)F InChI=1S/C7H7F3N2O3S/c1-15-6-5(16(11,13)14)4(2-3-12-6)7(8,9)10/h2-3H,1H3,(H2,11,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The United Kingdom Pyroxsulam 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam. 30Apr2013 2013 doi:10.2903/j.efsa.2013.3182
+Pyroxsulam 422556-08-9 single chemical entity Component is a metabolite of the substance 2-Methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide 2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide 2-Methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide C7H7F3N2O3S COc1nccc(c1S(N)(=O)=O)C(F)(F)F InChI=1S/C7H7F3N2O3S/c1-15-6-5(16(11,13)14)4(2-3-12-6)7(8,9)10/h2-3H,1H3,(H2,11,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The United Kingdom Pyroxsulam 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam. 30Apr2013 2013 doi:10.2903/j.efsa.2013.3182
+Pyroxsulam 422556-08-9 single chemical entity Component is a metabolite of the substance 2-Methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide 2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide 2-Methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide C7H7F3N2O3S COc1nccc(c1S(N)(=O)=O)C(F)(F)F InChI=1S/C7H7F3N2O3S/c1-15-6-5(16(11,13)14)4(2-3-12-6)7(8,9)10/h2-3H,1H3,(H2,11,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The United Kingdom Pyroxsulam 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam. 30Apr2013 2013 doi:10.2903/j.efsa.2013.3182
+Pyroxsulam 422556-08-9 single chemical entity Component is a metabolite of the substance 2-Methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide 2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide 2-Methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide C7H7F3N2O3S COc1nccc(c1S(N)(=O)=O)C(F)(F)F InChI=1S/C7H7F3N2O3S/c1-15-6-5(16(11,13)14)4(2-3-12-6)7(8,9)10/h2-3H,1H3,(H2,11,13,14) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Rat (as animal) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Pyroxsulam 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam. 30Apr2013 2013 doi:10.2903/j.efsa.2013.3182
+Pyroxsulam 422556-08-9 single chemical entity Component is a metabolite of the substance 2-Methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide 2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide 2-Methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide C7H7F3N2O3S COc1nccc(c1S(N)(=O)=O)C(F)(F)F InChI=1S/C7H7F3N2O3S/c1-15-6-5(16(11,13)14)4(2-3-12-6)7(8,9)10/h2-3H,1H3,(H2,11,13,14) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Rat (as animal) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Pyroxsulam 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam. 30Apr2013 2013 doi:10.2903/j.efsa.2013.3182
+Pyroxsulam 422556-08-9 single chemical entity Component is a metabolite of the substance 2-Methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide 2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide 2-Methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide C7H7F3N2O3S COc1nccc(c1S(N)(=O)=O)C(F)(F)F InChI=1S/C7H7F3N2O3S/c1-15-6-5(16(11,13)14)4(2-3-12-6)7(8,9)10/h2-3H,1H3,(H2,11,13,14) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: The United Kingdom Pyroxsulam 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam. 30Apr2013 2013 doi:10.2903/j.efsa.2013.3182
+Pyroxsulam 422556-08-9 single chemical entity Component is a metabolite of the substance 2-Methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide 2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide 2-Methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide C7H7F3N2O3S COc1nccc(c1S(N)(=O)=O)C(F)(F)F InChI=1S/C7H7F3N2O3S/c1-15-6-5(16(11,13)14)4(2-3-12-6)7(8,9)10/h2-3H,1H3,(H2,11,13,14) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: The United Kingdom Pyroxsulam 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam. 30Apr2013 2013 doi:10.2903/j.efsa.2013.3182
+Prothioconazole 178928-70-6 single chemical entity Component is identical to the substance Prothioconazole 178928-70-6 2-[2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1H-1,2, 4-triazole-3-thione Prothioconazole C14H15Cl2N3OS C1CC1(C(CC2=CC=CC=C2Cl)(CN3C(=S)N=CN3)O)Cl InChI=1S/C14H15Cl2N3OS/c15-11-4-2-1-3-10(11)7-14(20,13(16)5-6-13)8-19-12(21)17-9-18-19/h1-4,9,20H,5-8H2,(H,17,18,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is identical to the substance Prothioconazole 178928-70-6 2-[2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1H-1,2, 4-triazole-3-thione Prothioconazole C14H15Cl2N3OS C1CC1(C(CC2=CC=CC=C2Cl)(CN3C(=S)N=CN3)O)Cl InChI=1S/C14H15Cl2N3OS/c15-11-4-2-1-3-10(11)7-14(20,13(16)5-6-13)8-19-12(21)17-9-18-19/h1-4,9,20H,5-8H2,(H,17,18,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is identical to the substance Prothioconazole 178928-70-6 2-[2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1H-1,2, 4-triazole-3-thione Prothioconazole C14H15Cl2N3OS C1CC1(C(CC2=CC=CC=C2Cl)(CN3C(=S)N=CN3)O)Cl InChI=1S/C14H15Cl2N3OS/c15-11-4-2-1-3-10(11)7-14(20,13(16)5-6-13)8-19-12(21)17-9-18-19/h1-4,9,20H,5-8H2,(H,17,18,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported no data with Negative RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is identical to the substance Prothioconazole 178928-70-6 2-[2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1H-1,2, 4-triazole-3-thione Prothioconazole C14H15Cl2N3OS C1CC1(C(CC2=CC=CC=C2Cl)(CN3C(=S)N=CN3)O)Cl InChI=1S/C14H15Cl2N3OS/c15-11-4-2-1-3-10(11)7-14(20,13(16)5-6-13)8-19-12(21)17-9-18-19/h1-4,9,20H,5-8H2,(H,17,18,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is identical to the substance Prothioconazole 178928-70-6 2-[2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1H-1,2, 4-triazole-3-thione Prothioconazole C14H15Cl2N3OS C1CC1(C(CC2=CC=CC=C2Cl)(CN3C(=S)N=CN3)O)Cl InChI=1S/C14H15Cl2N3OS/c15-11-4-2-1-3-10(11)7-14(20,13(16)5-6-13)8-19-12(21)17-9-18-19/h1-4,9,20H,5-8H2,(H,17,18,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is identical to the substance Prothioconazole 178928-70-6 2-[2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1H-1,2, 4-triazole-3-thione Prothioconazole C14H15Cl2N3OS C1CC1(C(CC2=CC=CC=C2Cl)(CN3C(=S)N=CN3)O)Cl InChI=1S/C14H15Cl2N3OS/c15-11-4-2-1-3-10(11)7-14(20,13(16)5-6-13)8-19-12(21)17-9-18-19/h1-4,9,20H,5-8H2,(H,17,18,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is identical to the substance Prothioconazole 178928-70-6 2-[2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1H-1,2, 4-triazole-3-thione Prothioconazole C14H15Cl2N3OS C1CC1(C(CC2=CC=CC=C2Cl)(CN3C(=S)N=CN3)O)Cl InChI=1S/C14H15Cl2N3OS/c15-11-4-2-1-3-10(11)7-14(20,13(16)5-6-13)8-19-12(21)17-9-18-19/h1-4,9,20H,5-8H2,(H,17,18,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is identical to the substance Prothioconazole 178928-70-6 2-[2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1H-1,2, 4-triazole-3-thione Prothioconazole C14H15Cl2N3OS C1CC1(C(CC2=CC=CC=C2Cl)(CN3C(=S)N=CN3)O)Cl InChI=1S/C14H15Cl2N3OS/c15-11-4-2-1-3-10(11)7-14(20,13(16)5-6-13)8-19-12(21)17-9-18-19/h1-4,9,20H,5-8H2,(H,17,18,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is identical to the substance Prothioconazole 178928-70-6 2-[2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1H-1,2, 4-triazole-3-thione Prothioconazole C14H15Cl2N3OS C1CC1(C(CC2=CC=CC=C2Cl)(CN3C(=S)N=CN3)O)Cl InChI=1S/C14H15Cl2N3OS/c15-11-4-2-1-3-10(11)7-14(20,13(16)5-6-13)8-19-12(21)17-9-18-19/h1-4,9,20H,5-8H2,(H,17,18,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported no data without Negative RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is identical to the substance Prothioconazole 178928-70-6 2-[2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1H-1,2, 4-triazole-3-thione Prothioconazole C14H15Cl2N3OS C1CC1(C(CC2=CC=CC=C2Cl)(CN3C(=S)N=CN3)O)Cl InChI=1S/C14H15Cl2N3OS/c15-11-4-2-1-3-10(11)7-14(20,13(16)5-6-13)8-19-12(21)17-9-18-19/h1-4,9,20H,5-8H2,(H,17,18,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is identical to the substance Prothioconazole 178928-70-6 2-[2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1H-1,2, 4-triazole-3-thione Prothioconazole C14H15Cl2N3OS C1CC1(C(CC2=CC=CC=C2Cl)(CN3C(=S)N=CN3)O)Cl InChI=1S/C14H15Cl2N3OS/c15-11-4-2-1-3-10(11)7-14(20,13(16)5-6-13)8-19-12(21)17-9-18-19/h1-4,9,20H,5-8H2,(H,17,18,21) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Positive RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is identical to the substance Prothioconazole 178928-70-6 2-[2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1H-1,2, 4-triazole-3-thione Prothioconazole C14H15Cl2N3OS C1CC1(C(CC2=CC=CC=C2Cl)(CN3C(=S)N=CN3)O)Cl InChI=1S/C14H15Cl2N3OS/c15-11-4-2-1-3-10(11)7-14(20,13(16)5-6-13)8-19-12(21)17-9-18-19/h1-4,9,20H,5-8H2,(H,17,18,21) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Positive RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is identical to the substance Prothioconazole 178928-70-6 2-[2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1H-1,2, 4-triazole-3-thione Prothioconazole C14H15Cl2N3OS C1CC1(C(CC2=CC=CC=C2Cl)(CN3C(=S)N=CN3)O)Cl InChI=1S/C14H15Cl2N3OS/c15-11-4-2-1-3-10(11)7-14(20,13(16)5-6-13)8-19-12(21)17-9-18-19/h1-4,9,20H,5-8H2,(H,17,18,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is identical to the substance Prothioconazole 178928-70-6 2-[2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1H-1,2, 4-triazole-3-thione Prothioconazole C14H15Cl2N3OS C1CC1(C(CC2=CC=CC=C2Cl)(CN3C(=S)N=CN3)O)Cl InChI=1S/C14H15Cl2N3OS/c15-11-4-2-1-3-10(11)7-14(20,13(16)5-6-13)8-19-12(21)17-9-18-19/h1-4,9,20H,5-8H2,(H,17,18,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is identical to the substance Prothioconazole 178928-70-6 2-[2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1H-1,2, 4-triazole-3-thione Prothioconazole C14H15Cl2N3OS C1CC1(C(CC2=CC=CC=C2Cl)(CN3C(=S)N=CN3)O)Cl InChI=1S/C14H15Cl2N3OS/c15-11-4-2-1-3-10(11)7-14(20,13(16)5-6-13)8-19-12(21)17-9-18-19/h1-4,9,20H,5-8H2,(H,17,18,21) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Ambiguous RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is identical to the substance Prothioconazole 178928-70-6 2-[2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1H-1,2, 4-triazole-3-thione Prothioconazole C14H15Cl2N3OS C1CC1(C(CC2=CC=CC=C2Cl)(CN3C(=S)N=CN3)O)Cl InChI=1S/C14H15Cl2N3OS/c15-11-4-2-1-3-10(11)7-14(20,13(16)5-6-13)8-19-12(21)17-9-18-19/h1-4,9,20H,5-8H2,(H,17,18,21) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Wistar 4 Male oral: gavage 4.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is identical to the substance Prothioconazole 178928-70-6 2-[2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1H-1,2, 4-triazole-3-thione Prothioconazole C14H15Cl2N3OS C1CC1(C(CC2=CC=CC=C2Cl)(CN3C(=S)N=CN3)O)Cl InChI=1S/C14H15Cl2N3OS/c15-11-4-2-1-3-10(11)7-14(20,13(16)5-6-13)8-19-12(21)17-9-18-19/h1-4,9,20H,5-8H2,(H,17,18,21) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Wistar 4 Male oral: gavage 16.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is identical to the substance Prothioconazole 178928-70-6 2-[2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1H-1,2, 4-triazole-3-thione Prothioconazole C14H15Cl2N3OS C1CC1(C(CC2=CC=CC=C2Cl)(CN3C(=S)N=CN3)O)Cl InChI=1S/C14H15Cl2N3OS/c15-11-4-2-1-3-10(11)7-14(20,13(16)5-6-13)8-19-12(21)17-9-18-19/h1-4,9,20H,5-8H2,(H,17,18,21) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 10 Male/Female intraperitoneal 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is identical to the substance Prothioconazole 178928-70-6 2-[2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1H-1,2, 4-triazole-3-thione Prothioconazole C14H15Cl2N3OS C1CC1(C(CC2=CC=CC=C2Cl)(CN3C(=S)N=CN3)O)Cl InChI=1S/C14H15Cl2N3OS/c15-11-4-2-1-3-10(11)7-14(20,13(16)5-6-13)8-19-12(21)17-9-18-19/h1-4,9,20H,5-8H2,(H,17,18,21) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 10 Male/Female intraperitoneal 16.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is identical to the substance Prothioconazole 178928-70-6 2-[2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1H-1,2, 4-triazole-3-thione Prothioconazole C14H15Cl2N3OS C1CC1(C(CC2=CC=CC=C2Cl)(CN3C(=S)N=CN3)O)Cl InChI=1S/C14H15Cl2N3OS/c15-11-4-2-1-3-10(11)7-14(20,13(16)5-6-13)8-19-12(21)17-9-18-19/h1-4,9,20H,5-8H2,(H,17,18,21) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 10 Male/Female intraperitoneal 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is identical to the substance Prothioconazole 178928-70-6 2-[2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1H-1,2, 4-triazole-3-thione Prothioconazole C14H15Cl2N3OS C1CC1(C(CC2=CC=CC=C2Cl)(CN3C(=S)N=CN3)O)Cl InChI=1S/C14H15Cl2N3OS/c15-11-4-2-1-3-10(11)7-14(20,13(16)5-6-13)8-19-12(21)17-9-18-19/h1-4,9,20H,5-8H2,(H,17,18,21) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI Male intraperitoneal 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is a metabolite of the substance 1-(2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl)-1Hpyrazole-5-sulfonic acid 1-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1H-pyrazole-5-sulfonic acid Not in list C15H16Cl2N2O4S OC(Cn1nccc1S(=O)(=O)O)(Cc2ccccc2Cl)C3(Cl)CC3 InChI=1S/C15H16Cl2N2O4S/c16-12-4-2-1-3-11(12)9-15(20,14(17)6-7-14)10-19-13(5-8-18-19)24(21,22)23/h1-5,8,20H,6-7,9-10H2,(H,21,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is a metabolite of the substance 1-(2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl)-1Hpyrazole-5-sulfonic acid 1-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1H-pyrazole-5-sulfonic acid Not in list C15H16Cl2N2O4S OC(Cn1nccc1S(=O)(=O)O)(Cc2ccccc2Cl)C3(Cl)CC3 InChI=1S/C15H16Cl2N2O4S/c16-12-4-2-1-3-11(12)9-15(20,14(17)6-7-14)10-19-13(5-8-18-19)24(21,22)23/h1-5,8,20H,6-7,9-10H2,(H,21,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is a metabolite of the substance 1-(2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl)-1Hpyrazole-5-sulfonic acid 1-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1H-pyrazole-5-sulfonic acid Not in list C15H16Cl2N2O4S OC(Cn1nccc1S(=O)(=O)O)(Cc2ccccc2Cl)C3(Cl)CC3 InChI=1S/C15H16Cl2N2O4S/c16-12-4-2-1-3-11(12)9-15(20,14(17)6-7-14)10-19-13(5-8-18-19)24(21,22)23/h1-5,8,20H,6-7,9-10H2,(H,21,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is a metabolite of the substance 1-(2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl)-1Hpyrazole-5-sulfonic acid 1-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1H-pyrazole-5-sulfonic acid Not in list C15H16Cl2N2O4S OC(Cn1nccc1S(=O)(=O)O)(Cc2ccccc2Cl)C3(Cl)CC3 InChI=1S/C15H16Cl2N2O4S/c16-12-4-2-1-3-11(12)9-15(20,14(17)6-7-14)10-19-13(5-8-18-19)24(21,22)23/h1-5,8,20H,6-7,9-10H2,(H,21,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is a metabolite of the substance 1-(2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl)-1Hpyrazole-5-sulfonic acid 1-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1H-pyrazole-5-sulfonic acid Not in list C15H16Cl2N2O4S OC(Cn1nccc1S(=O)(=O)O)(Cc2ccccc2Cl)C3(Cl)CC3 InChI=1S/C15H16Cl2N2O4S/c16-12-4-2-1-3-11(12)9-15(20,14(17)6-7-14)10-19-13(5-8-18-19)24(21,22)23/h1-5,8,20H,6-7,9-10H2,(H,21,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is a metabolite of the substance 1-(2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl)-1Hpyrazole-5-sulfonic acid 1-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1H-pyrazole-5-sulfonic acid Not in list C15H16Cl2N2O4S OC(Cn1nccc1S(=O)(=O)O)(Cc2ccccc2Cl)C3(Cl)CC3 InChI=1S/C15H16Cl2N2O4S/c16-12-4-2-1-3-11(12)9-15(20,14(17)6-7-14)10-19-13(5-8-18-19)24(21,22)23/h1-5,8,20H,6-7,9-10H2,(H,21,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is a metabolite of the substance 1-(2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl)-1Hpyrazole-5-sulfonic acid 1-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1H-pyrazole-5-sulfonic acid Not in list C15H16Cl2N2O4S OC(Cn1nccc1S(=O)(=O)O)(Cc2ccccc2Cl)C3(Cl)CC3 InChI=1S/C15H16Cl2N2O4S/c16-12-4-2-1-3-11(12)9-15(20,14(17)6-7-14)10-19-13(5-8-18-19)24(21,22)23/h1-5,8,20H,6-7,9-10H2,(H,21,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is a metabolite of the substance 1-(2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl)-1Hpyrazole-5-sulfonic acid 1-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1H-pyrazole-5-sulfonic acid Not in list C15H16Cl2N2O4S OC(Cn1nccc1S(=O)(=O)O)(Cc2ccccc2Cl)C3(Cl)CC3 InChI=1S/C15H16Cl2N2O4S/c16-12-4-2-1-3-11(12)9-15(20,14(17)6-7-14)10-19-13(5-8-18-19)24(21,22)23/h1-5,8,20H,6-7,9-10H2,(H,21,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is a metabolite of the substance 1-(2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl)-1Hpyrazole-5-sulfonic acid 1-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1H-pyrazole-5-sulfonic acid Not in list C15H16Cl2N2O4S OC(Cn1nccc1S(=O)(=O)O)(Cc2ccccc2Cl)C3(Cl)CC3 InChI=1S/C15H16Cl2N2O4S/c16-12-4-2-1-3-11(12)9-15(20,14(17)6-7-14)10-19-13(5-8-18-19)24(21,22)23/h1-5,8,20H,6-7,9-10H2,(H,21,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is a metabolite of the substance 1-(2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl)-1Hpyrazole-5-sulfonic acid 1-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1H-pyrazole-5-sulfonic acid Not in list C15H16Cl2N2O4S OC(Cn1nccc1S(=O)(=O)O)(Cc2ccccc2Cl)C3(Cl)CC3 InChI=1S/C15H16Cl2N2O4S/c16-12-4-2-1-3-11(12)9-15(20,14(17)6-7-14)10-19-13(5-8-18-19)24(21,22)23/h1-5,8,20H,6-7,9-10H2,(H,21,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is a metabolite of the substance 1-(2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl)-1H-1,2,4-triazol-5(4H)-one 2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-2,4-dihydro-3H-1,2,4-triazol-3-one Not in list C14H15Cl2N3O2 O=C3NC=NN3CC(O)(Cc1ccccc1Cl)C2(Cl)CC2 InChI=1S/C14H15Cl2N3O2/c15-11-4-2-1-3-10(11)7-14(21,13(16)5-6-13)8-19-12(20)17-9-18-19/h1-4,9,21H,5-8H2,(H,17,18,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is a metabolite of the substance 1-(2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl)-1H-1,2,4-triazol-5(4H)-one 2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-2,4-dihydro-3H-1,2,4-triazol-3-one Not in list C14H15Cl2N3O2 O=C3NC=NN3CC(O)(Cc1ccccc1Cl)C2(Cl)CC2 InChI=1S/C14H15Cl2N3O2/c15-11-4-2-1-3-10(11)7-14(21,13(16)5-6-13)8-19-12(20)17-9-18-19/h1-4,9,21H,5-8H2,(H,17,18,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is a metabolite of the substance 1-(2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl)-1H-1,2,4-triazol-5(4H)-one 2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-2,4-dihydro-3H-1,2,4-triazol-3-one Not in list C14H15Cl2N3O2 O=C3NC=NN3CC(O)(Cc1ccccc1Cl)C2(Cl)CC2 InChI=1S/C14H15Cl2N3O2/c15-11-4-2-1-3-10(11)7-14(21,13(16)5-6-13)8-19-12(20)17-9-18-19/h1-4,9,21H,5-8H2,(H,17,18,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is a metabolite of the substance 1-(2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl)-1H-1,2,4-triazol-5(4H)-one 2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-2,4-dihydro-3H-1,2,4-triazol-3-one Not in list C14H15Cl2N3O2 O=C3NC=NN3CC(O)(Cc1ccccc1Cl)C2(Cl)CC2 InChI=1S/C14H15Cl2N3O2/c15-11-4-2-1-3-10(11)7-14(21,13(16)5-6-13)8-19-12(20)17-9-18-19/h1-4,9,21H,5-8H2,(H,17,18,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is a metabolite of the substance 1-(2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl)-1H-1,2,4-triazol-5(4H)-one 2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-2,4-dihydro-3H-1,2,4-triazol-3-one Not in list C14H15Cl2N3O2 O=C3NC=NN3CC(O)(Cc1ccccc1Cl)C2(Cl)CC2 InChI=1S/C14H15Cl2N3O2/c15-11-4-2-1-3-10(11)7-14(21,13(16)5-6-13)8-19-12(20)17-9-18-19/h1-4,9,21H,5-8H2,(H,17,18,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is a metabolite of the substance 1-(2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl)-1H-1,2,4-triazol-5(4H)-one 2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-2,4-dihydro-3H-1,2,4-triazol-3-one Not in list C14H15Cl2N3O2 O=C3NC=NN3CC(O)(Cc1ccccc1Cl)C2(Cl)CC2 InChI=1S/C14H15Cl2N3O2/c15-11-4-2-1-3-10(11)7-14(21,13(16)5-6-13)8-19-12(20)17-9-18-19/h1-4,9,21H,5-8H2,(H,17,18,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is a metabolite of the substance 1-(2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl)-1H-1,2,4-triazol-5(4H)-one 2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-2,4-dihydro-3H-1,2,4-triazol-3-one Not in list C14H15Cl2N3O2 O=C3NC=NN3CC(O)(Cc1ccccc1Cl)C2(Cl)CC2 InChI=1S/C14H15Cl2N3O2/c15-11-4-2-1-3-10(11)7-14(21,13(16)5-6-13)8-19-12(20)17-9-18-19/h1-4,9,21H,5-8H2,(H,17,18,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is a metabolite of the substance 1-(2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl)-1H-1,2,4-triazol-5(4H)-one 2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-2,4-dihydro-3H-1,2,4-triazol-3-one Not in list C14H15Cl2N3O2 O=C3NC=NN3CC(O)(Cc1ccccc1Cl)C2(Cl)CC2 InChI=1S/C14H15Cl2N3O2/c15-11-4-2-1-3-10(11)7-14(21,13(16)5-6-13)8-19-12(20)17-9-18-19/h1-4,9,21H,5-8H2,(H,17,18,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is a metabolite of the substance 1-(2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl)-1H-1,2,4-triazol-5(4H)-one 2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-2,4-dihydro-3H-1,2,4-triazol-3-one Not in list C14H15Cl2N3O2 O=C3NC=NN3CC(O)(Cc1ccccc1Cl)C2(Cl)CC2 InChI=1S/C14H15Cl2N3O2/c15-11-4-2-1-3-10(11)7-14(21,13(16)5-6-13)8-19-12(20)17-9-18-19/h1-4,9,21H,5-8H2,(H,17,18,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is a metabolite of the substance 1-(2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl)-1H-1,2,4-triazol-5(4H)-one 2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-2,4-dihydro-3H-1,2,4-triazol-3-one Not in list C14H15Cl2N3O2 O=C3NC=NN3CC(O)(Cc1ccccc1Cl)C2(Cl)CC2 InChI=1S/C14H15Cl2N3O2/c15-11-4-2-1-3-10(11)7-14(21,13(16)5-6-13)8-19-12(20)17-9-18-19/h1-4,9,21H,5-8H2,(H,17,18,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is a metabolite of the substance 2-(1-Chlorocyclopropyl)-1-(2-chlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propane-1,2-diol 2-(1-chlorocyclopropyl)-1-(2-chlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propane-1,2-diol Not in list C14H15Cl2N3O2 OC(Cn1cncn1)(C(O)c2ccccc2Cl)C3(Cl)CC3 InChI=1/C14H15Cl2N3O2/c15-11-4-2-1-3-10(11)12(20)14(21,13(16)5-6-13)7-19-9-17-8-18-19/h1-4,8-9,12,20-21H,5-7H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is a metabolite of the substance 2-(1-Chlorocyclopropyl)-1-(2-chlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propane-1,2-diol 2-(1-chlorocyclopropyl)-1-(2-chlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propane-1,2-diol Not in list C14H15Cl2N3O2 OC(Cn1cncn1)(C(O)c2ccccc2Cl)C3(Cl)CC3 InChI=1/C14H15Cl2N3O2/c15-11-4-2-1-3-10(11)12(20)14(21,13(16)5-6-13)7-19-9-17-8-18-19/h1-4,8-9,12,20-21H,5-7H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is a metabolite of the substance 2-(1-Chlorocyclopropyl)-1-(2-chlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propane-1,2-diol 2-(1-chlorocyclopropyl)-1-(2-chlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propane-1,2-diol Not in list C14H15Cl2N3O2 OC(Cn1cncn1)(C(O)c2ccccc2Cl)C3(Cl)CC3 InChI=1/C14H15Cl2N3O2/c15-11-4-2-1-3-10(11)12(20)14(21,13(16)5-6-13)7-19-9-17-8-18-19/h1-4,8-9,12,20-21H,5-7H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is a metabolite of the substance 2-(1-Chlorocyclopropyl)-1-(2-chlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propane-1,2-diol 2-(1-chlorocyclopropyl)-1-(2-chlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propane-1,2-diol Not in list C14H15Cl2N3O2 OC(Cn1cncn1)(C(O)c2ccccc2Cl)C3(Cl)CC3 InChI=1/C14H15Cl2N3O2/c15-11-4-2-1-3-10(11)12(20)14(21,13(16)5-6-13)7-19-9-17-8-18-19/h1-4,8-9,12,20-21H,5-7H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is a metabolite of the substance 2-(1-Chlorocyclopropyl)-1-(2-chlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propane-1,2-diol 2-(1-chlorocyclopropyl)-1-(2-chlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propane-1,2-diol Not in list C14H15Cl2N3O2 OC(Cn1cncn1)(C(O)c2ccccc2Cl)C3(Cl)CC3 InChI=1/C14H15Cl2N3O2/c15-11-4-2-1-3-10(11)12(20)14(21,13(16)5-6-13)7-19-9-17-8-18-19/h1-4,8-9,12,20-21H,5-7H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is a metabolite of the substance 2-(1-Chlorocyclopropyl)-1-(2-chlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propane-1,2-diol 2-(1-chlorocyclopropyl)-1-(2-chlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propane-1,2-diol Not in list C14H15Cl2N3O2 OC(Cn1cncn1)(C(O)c2ccccc2Cl)C3(Cl)CC3 InChI=1/C14H15Cl2N3O2/c15-11-4-2-1-3-10(11)12(20)14(21,13(16)5-6-13)7-19-9-17-8-18-19/h1-4,8-9,12,20-21H,5-7H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is a metabolite of the substance 2-(1-Chlorocyclopropyl)-1-(2-chlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propane-1,2-diol 2-(1-chlorocyclopropyl)-1-(2-chlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propane-1,2-diol Not in list C14H15Cl2N3O2 OC(Cn1cncn1)(C(O)c2ccccc2Cl)C3(Cl)CC3 InChI=1/C14H15Cl2N3O2/c15-11-4-2-1-3-10(11)12(20)14(21,13(16)5-6-13)7-19-9-17-8-18-19/h1-4,8-9,12,20-21H,5-7H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is a metabolite of the substance 2-(1-Chlorocyclopropyl)-1-(2-chlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propane-1,2-diol 2-(1-chlorocyclopropyl)-1-(2-chlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propane-1,2-diol Not in list C14H15Cl2N3O2 OC(Cn1cncn1)(C(O)c2ccccc2Cl)C3(Cl)CC3 InChI=1/C14H15Cl2N3O2/c15-11-4-2-1-3-10(11)12(20)14(21,13(16)5-6-13)7-19-9-17-8-18-19/h1-4,8-9,12,20-21H,5-7H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is a metabolite of the substance 2-(1-Chlorocyclopropyl)-1-(2-chlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propane-1,2-diol 2-(1-chlorocyclopropyl)-1-(2-chlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propane-1,2-diol Not in list C14H15Cl2N3O2 OC(Cn1cncn1)(C(O)c2ccccc2Cl)C3(Cl)CC3 InChI=1/C14H15Cl2N3O2/c15-11-4-2-1-3-10(11)12(20)14(21,13(16)5-6-13)7-19-9-17-8-18-19/h1-4,8-9,12,20-21H,5-7H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is a metabolite of the substance 2-(1-Chlorocyclopropyl)-1-(2-chlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propane-1,2-diol 2-(1-chlorocyclopropyl)-1-(2-chlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propane-1,2-diol Not in list C14H15Cl2N3O2 OC(Cn1cncn1)(C(O)c2ccccc2Cl)C3(Cl)CC3 InChI=1/C14H15Cl2N3O2/c15-11-4-2-1-3-10(11)12(20)14(21,13(16)5-6-13)7-19-9-17-8-18-19/h1-4,8-9,12,20-21H,5-7H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is a metabolite of the substance 2-(1-Chlorocyclopropyl)-1-(2-chlorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl acetate 2-(1-chlorocyclopropyl)-1-(2-chlorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl acetate Not in list C16H17Cl2N3O3 OC(Cn1cncn1)(C(OC(C)=O)c2ccccc2Cl)C3(Cl)CC3 InChI=1S/C16H17Cl2N3O3/c1-11(22)24-14(12-4-2-3-5-13(12)17)16(23,15(18)6-7-15)8-21-10-19-9-20-21/h2-5,9-10,14,23H,6-8H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is a metabolite of the substance 2-(1-Chlorocyclopropyl)-1-(2-chlorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl acetate 2-(1-chlorocyclopropyl)-1-(2-chlorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl acetate Not in list C16H17Cl2N3O3 OC(Cn1cncn1)(C(OC(C)=O)c2ccccc2Cl)C3(Cl)CC3 InChI=1S/C16H17Cl2N3O3/c1-11(22)24-14(12-4-2-3-5-13(12)17)16(23,15(18)6-7-15)8-21-10-19-9-20-21/h2-5,9-10,14,23H,6-8H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is a metabolite of the substance 2-(1-Chlorocyclopropyl)-1-(2-chlorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl acetate 2-(1-chlorocyclopropyl)-1-(2-chlorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl acetate Not in list C16H17Cl2N3O3 OC(Cn1cncn1)(C(OC(C)=O)c2ccccc2Cl)C3(Cl)CC3 InChI=1S/C16H17Cl2N3O3/c1-11(22)24-14(12-4-2-3-5-13(12)17)16(23,15(18)6-7-15)8-21-10-19-9-20-21/h2-5,9-10,14,23H,6-8H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is a metabolite of the substance 2-(1-Chlorocyclopropyl)-1-(2-chlorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl acetate 2-(1-chlorocyclopropyl)-1-(2-chlorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl acetate Not in list C16H17Cl2N3O3 OC(Cn1cncn1)(C(OC(C)=O)c2ccccc2Cl)C3(Cl)CC3 InChI=1S/C16H17Cl2N3O3/c1-11(22)24-14(12-4-2-3-5-13(12)17)16(23,15(18)6-7-15)8-21-10-19-9-20-21/h2-5,9-10,14,23H,6-8H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is a metabolite of the substance 2-(1-Chlorocyclopropyl)-1-(2-chlorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl acetate 2-(1-chlorocyclopropyl)-1-(2-chlorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl acetate Not in list C16H17Cl2N3O3 OC(Cn1cncn1)(C(OC(C)=O)c2ccccc2Cl)C3(Cl)CC3 InChI=1S/C16H17Cl2N3O3/c1-11(22)24-14(12-4-2-3-5-13(12)17)16(23,15(18)6-7-15)8-21-10-19-9-20-21/h2-5,9-10,14,23H,6-8H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is a metabolite of the substance 2-(1-Chlorocyclopropyl)-1-(2-chlorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl acetate 2-(1-chlorocyclopropyl)-1-(2-chlorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl acetate Not in list C16H17Cl2N3O3 OC(Cn1cncn1)(C(OC(C)=O)c2ccccc2Cl)C3(Cl)CC3 InChI=1S/C16H17Cl2N3O3/c1-11(22)24-14(12-4-2-3-5-13(12)17)16(23,15(18)6-7-15)8-21-10-19-9-20-21/h2-5,9-10,14,23H,6-8H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is a metabolite of the substance 2-(1-Chlorocyclopropyl)-1-(2-chlorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl acetate 2-(1-chlorocyclopropyl)-1-(2-chlorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl acetate Not in list C16H17Cl2N3O3 OC(Cn1cncn1)(C(OC(C)=O)c2ccccc2Cl)C3(Cl)CC3 InChI=1S/C16H17Cl2N3O3/c1-11(22)24-14(12-4-2-3-5-13(12)17)16(23,15(18)6-7-15)8-21-10-19-9-20-21/h2-5,9-10,14,23H,6-8H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is a metabolite of the substance 2-(1-Chlorocyclopropyl)-1-(2-chlorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl acetate 2-(1-chlorocyclopropyl)-1-(2-chlorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl acetate Not in list C16H17Cl2N3O3 OC(Cn1cncn1)(C(OC(C)=O)c2ccccc2Cl)C3(Cl)CC3 InChI=1S/C16H17Cl2N3O3/c1-11(22)24-14(12-4-2-3-5-13(12)17)16(23,15(18)6-7-15)8-21-10-19-9-20-21/h2-5,9-10,14,23H,6-8H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is a metabolite of the substance 2-(1-Chlorocyclopropyl)-1-(2-chlorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl acetate 2-(1-chlorocyclopropyl)-1-(2-chlorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl acetate Not in list C16H17Cl2N3O3 OC(Cn1cncn1)(C(OC(C)=O)c2ccccc2Cl)C3(Cl)CC3 InChI=1S/C16H17Cl2N3O3/c1-11(22)24-14(12-4-2-3-5-13(12)17)16(23,15(18)6-7-15)8-21-10-19-9-20-21/h2-5,9-10,14,23H,6-8H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is a metabolite of the substance 2-(1-Chlorocyclopropyl)-1-(2-chlorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl acetate 2-(1-chlorocyclopropyl)-1-(2-chlorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl acetate Not in list C16H17Cl2N3O3 OC(Cn1cncn1)(C(OC(C)=O)c2ccccc2Cl)C3(Cl)CC3 InChI=1S/C16H17Cl2N3O3/c1-11(22)24-14(12-4-2-3-5-13(12)17)16(23,15(18)6-7-15)8-21-10-19-9-20-21/h2-5,9-10,14,23H,6-8H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is a metabolite of the substance 2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)propane-1,2-diol 2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)propane-1,2-diol Not in list C12H14Cl2O2 OCC(O)(Cc1ccccc1Cl)C2(Cl)CC2 InChI=1S/C12H14Cl2O2/c13-10-4-2-1-3-9(10)7-12(16,8-15)11(14)5-6-11/h1-4,15-16H,5-8H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is a metabolite of the substance 2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)propane-1,2-diol 2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)propane-1,2-diol Not in list C12H14Cl2O2 OCC(O)(Cc1ccccc1Cl)C2(Cl)CC2 InChI=1S/C12H14Cl2O2/c13-10-4-2-1-3-9(10)7-12(16,8-15)11(14)5-6-11/h1-4,15-16H,5-8H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is a metabolite of the substance 2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)propane-1,2-diol 2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)propane-1,2-diol Not in list C12H14Cl2O2 OCC(O)(Cc1ccccc1Cl)C2(Cl)CC2 InChI=1S/C12H14Cl2O2/c13-10-4-2-1-3-9(10)7-12(16,8-15)11(14)5-6-11/h1-4,15-16H,5-8H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is a metabolite of the substance 2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)propane-1,2-diol 2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)propane-1,2-diol Not in list C12H14Cl2O2 OCC(O)(Cc1ccccc1Cl)C2(Cl)CC2 InChI=1S/C12H14Cl2O2/c13-10-4-2-1-3-9(10)7-12(16,8-15)11(14)5-6-11/h1-4,15-16H,5-8H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is a metabolite of the substance 2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)propane-1,2-diol 2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)propane-1,2-diol Not in list C12H14Cl2O2 OCC(O)(Cc1ccccc1Cl)C2(Cl)CC2 InChI=1S/C12H14Cl2O2/c13-10-4-2-1-3-9(10)7-12(16,8-15)11(14)5-6-11/h1-4,15-16H,5-8H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is a metabolite of the substance 2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)propane-1,2-diol 2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)propane-1,2-diol Not in list C12H14Cl2O2 OCC(O)(Cc1ccccc1Cl)C2(Cl)CC2 InChI=1S/C12H14Cl2O2/c13-10-4-2-1-3-9(10)7-12(16,8-15)11(14)5-6-11/h1-4,15-16H,5-8H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is a metabolite of the substance 2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)propane-1,2-diol 2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)propane-1,2-diol Not in list C12H14Cl2O2 OCC(O)(Cc1ccccc1Cl)C2(Cl)CC2 InChI=1S/C12H14Cl2O2/c13-10-4-2-1-3-9(10)7-12(16,8-15)11(14)5-6-11/h1-4,15-16H,5-8H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is a metabolite of the substance 2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)propane-1,2-diol 2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)propane-1,2-diol Not in list C12H14Cl2O2 OCC(O)(Cc1ccccc1Cl)C2(Cl)CC2 InChI=1S/C12H14Cl2O2/c13-10-4-2-1-3-9(10)7-12(16,8-15)11(14)5-6-11/h1-4,15-16H,5-8H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is a metabolite of the substance 2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)propane-1,2-diol 2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)propane-1,2-diol Not in list C12H14Cl2O2 OCC(O)(Cc1ccccc1Cl)C2(Cl)CC2 InChI=1S/C12H14Cl2O2/c13-10-4-2-1-3-9(10)7-12(16,8-15)11(14)5-6-11/h1-4,15-16H,5-8H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Prothioconazole 178928-70-6 single chemical entity Component is a metabolite of the substance 2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)propane-1,2-diol 2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)propane-1,2-diol Not in list C12H14Cl2O2 OCC(O)(Cc1ccccc1Cl)C2(Cl)CC2 InChI=1S/C12H14Cl2O2/c13-10-4-2-1-3-9(10)7-12(16,8-15)11(14)5-6-11/h1-4,15-16H,5-8H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Prothioconazole (JAU 6476) 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole 01Aug2007 2007 doi:10.2903/j.efsa.2007.106r
+Penoxsulam 219714-96-2 single chemical entity Component is identical to the substance Penoxsulam (DE 638) 219714-96-2 2-(2,2-difluoroethoxy)-N-(5,8-dimethoxy-[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide Penoxsulam C16H14F5N5O5S COC1=CN=C(N2C1=NC(=N2)NS(=O)(=O)C3=C(C=CC=C3OCC(F)F)C(F)(F)F)OC InChI=1S/C16H14F5N5O5S/c1-29-10-6-22-15(30-2)26-13(10)23-14(24-26)25-32(27,28)12-8(16(19,20)21)4-3-5-9(12)31-7-11(17)18/h3-6,11H,7H2,1-2H3,(H,24,25) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Italy Penoxsulam (DE-638) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance penoxsulam 22Sep2009 2009 doi:10.2903/j.efsa.2009.343r
+Penoxsulam 219714-96-2 single chemical entity Component is identical to the substance Penoxsulam (DE 638) 219714-96-2 2-(2,2-difluoroethoxy)-N-(5,8-dimethoxy-[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide Penoxsulam C16H14F5N5O5S COC1=CN=C(N2C1=NC(=N2)NS(=O)(=O)C3=C(C=CC=C3OCC(F)F)C(F)(F)F)OC InChI=1S/C16H14F5N5O5S/c1-29-10-6-22-15(30-2)26-13(10)23-14(24-26)25-32(27,28)12-8(16(19,20)21)4-3-5-9(12)31-7-11(17)18/h3-6,11H,7H2,1-2H3,(H,24,25) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Italy Penoxsulam (DE-638) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance penoxsulam 22Sep2009 2009 doi:10.2903/j.efsa.2009.343r
+Penoxsulam 219714-96-2 single chemical entity Component is identical to the substance Penoxsulam (DE 638) 219714-96-2 2-(2,2-difluoroethoxy)-N-(5,8-dimethoxy-[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide Penoxsulam C16H14F5N5O5S COC1=CN=C(N2C1=NC(=N2)NS(=O)(=O)C3=C(C=CC=C3OCC(F)F)C(F)(F)F)OC InChI=1S/C16H14F5N5O5S/c1-29-10-6-22-15(30-2)26-13(10)23-14(24-26)25-32(27,28)12-8(16(19,20)21)4-3-5-9(12)31-7-11(17)18/h3-6,11H,7H2,1-2H3,(H,24,25) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Italy Penoxsulam (DE-638) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance penoxsulam 22Sep2009 2009 doi:10.2903/j.efsa.2009.343r
+Penoxsulam 219714-96-2 single chemical entity Component is identical to the substance Penoxsulam (DE 638) 219714-96-2 2-(2,2-difluoroethoxy)-N-(5,8-dimethoxy-[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide Penoxsulam C16H14F5N5O5S COC1=CN=C(N2C1=NC(=N2)NS(=O)(=O)C3=C(C=CC=C3OCC(F)F)C(F)(F)F)OC InChI=1S/C16H14F5N5O5S/c1-29-10-6-22-15(30-2)26-13(10)23-14(24-26)25-32(27,28)12-8(16(19,20)21)4-3-5-9(12)31-7-11(17)18/h3-6,11H,7H2,1-2H3,(H,24,25) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Italy Penoxsulam (DE-638) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance penoxsulam 22Sep2009 2009 doi:10.2903/j.efsa.2009.343r
+Penoxsulam 219714-96-2 single chemical entity Component is identical to the substance Penoxsulam (DE 638) 219714-96-2 2-(2,2-difluoroethoxy)-N-(5,8-dimethoxy-[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide Penoxsulam C16H14F5N5O5S COC1=CN=C(N2C1=NC(=N2)NS(=O)(=O)C3=C(C=CC=C3OCC(F)F)C(F)(F)F)OC InChI=1S/C16H14F5N5O5S/c1-29-10-6-22-15(30-2)26-13(10)23-14(24-26)25-32(27,28)12-8(16(19,20)21)4-3-5-9(12)31-7-11(17)18/h3-6,11H,7H2,1-2H3,(H,24,25) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Italy Penoxsulam (DE-638) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance penoxsulam 22Sep2009 2009 doi:10.2903/j.efsa.2009.343r
+Penoxsulam 219714-96-2 single chemical entity Component is identical to the substance Penoxsulam (DE 638) 219714-96-2 2-(2,2-difluoroethoxy)-N-(5,8-dimethoxy-[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide Penoxsulam C16H14F5N5O5S COC1=CN=C(N2C1=NC(=N2)NS(=O)(=O)C3=C(C=CC=C3OCC(F)F)C(F)(F)F)OC InChI=1S/C16H14F5N5O5S/c1-29-10-6-22-15(30-2)26-13(10)23-14(24-26)25-32(27,28)12-8(16(19,20)21)4-3-5-9(12)31-7-11(17)18/h3-6,11H,7H2,1-2H3,(H,24,25) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Italy Penoxsulam (DE-638) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance penoxsulam 22Sep2009 2009 doi:10.2903/j.efsa.2009.343r
+Penoxsulam 219714-96-2 single chemical entity Component is identical to the substance Penoxsulam (DE 638) 219714-96-2 2-(2,2-difluoroethoxy)-N-(5,8-dimethoxy-[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide Penoxsulam C16H14F5N5O5S COC1=CN=C(N2C1=NC(=N2)NS(=O)(=O)C3=C(C=CC=C3OCC(F)F)C(F)(F)F)OC InChI=1S/C16H14F5N5O5S/c1-29-10-6-22-15(30-2)26-13(10)23-14(24-26)25-32(27,28)12-8(16(19,20)21)4-3-5-9(12)31-7-11(17)18/h3-6,11H,7H2,1-2H3,(H,24,25) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Italy Penoxsulam (DE-638) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance penoxsulam 22Sep2009 2009 doi:10.2903/j.efsa.2009.343r
+Penoxsulam 219714-96-2 single chemical entity Component is identical to the substance Penoxsulam (DE 638) 219714-96-2 2-(2,2-difluoroethoxy)-N-(5,8-dimethoxy-[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide Penoxsulam C16H14F5N5O5S COC1=CN=C(N2C1=NC(=N2)NS(=O)(=O)C3=C(C=CC=C3OCC(F)F)C(F)(F)F)OC InChI=1S/C16H14F5N5O5S/c1-29-10-6-22-15(30-2)26-13(10)23-14(24-26)25-32(27,28)12-8(16(19,20)21)4-3-5-9(12)31-7-11(17)18/h3-6,11H,7H2,1-2H3,(H,24,25) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Italy Penoxsulam (DE-638) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance penoxsulam 22Sep2009 2009 doi:10.2903/j.efsa.2009.343r
+Penoxsulam 219714-96-2 single chemical entity Component is identical to the substance Penoxsulam (DE 638) 219714-96-2 2-(2,2-difluoroethoxy)-N-(5,8-dimethoxy-[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide Penoxsulam C16H14F5N5O5S COC1=CN=C(N2C1=NC(=N2)NS(=O)(=O)C3=C(C=CC=C3OCC(F)F)C(F)(F)F)OC InChI=1S/C16H14F5N5O5S/c1-29-10-6-22-15(30-2)26-13(10)23-14(24-26)25-32(27,28)12-8(16(19,20)21)4-3-5-9(12)31-7-11(17)18/h3-6,11H,7H2,1-2H3,(H,24,25) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Italy Penoxsulam (DE-638) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance penoxsulam 22Sep2009 2009 doi:10.2903/j.efsa.2009.343r
+Penoxsulam 219714-96-2 single chemical entity Component is identical to the substance Penoxsulam (DE 638) 219714-96-2 2-(2,2-difluoroethoxy)-N-(5,8-dimethoxy-[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide Penoxsulam C16H14F5N5O5S COC1=CN=C(N2C1=NC(=N2)NS(=O)(=O)C3=C(C=CC=C3OCC(F)F)C(F)(F)F)OC InChI=1S/C16H14F5N5O5S/c1-29-10-6-22-15(30-2)26-13(10)23-14(24-26)25-32(27,28)12-8(16(19,20)21)4-3-5-9(12)31-7-11(17)18/h3-6,11H,7H2,1-2H3,(H,24,25) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Italy Penoxsulam (DE-638) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance penoxsulam 22Sep2009 2009 doi:10.2903/j.efsa.2009.343r
+Penoxsulam 219714-96-2 single chemical entity Component is identical to the substance Penoxsulam (DE 638) 219714-96-2 2-(2,2-difluoroethoxy)-N-(5,8-dimethoxy-[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide Penoxsulam C16H14F5N5O5S COC1=CN=C(N2C1=NC(=N2)NS(=O)(=O)C3=C(C=CC=C3OCC(F)F)C(F)(F)F)OC InChI=1S/C16H14F5N5O5S/c1-29-10-6-22-15(30-2)26-13(10)23-14(24-26)25-32(27,28)12-8(16(19,20)21)4-3-5-9(12)31-7-11(17)18/h3-6,11H,7H2,1-2H3,(H,24,25) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Rat (as animal) lymphocytes Not reported yes without Negative RMS: Italy Penoxsulam (DE-638) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance penoxsulam 22Sep2009 2009 doi:10.2903/j.efsa.2009.343r
+Penoxsulam 219714-96-2 single chemical entity Component is identical to the substance Penoxsulam (DE 638) 219714-96-2 2-(2,2-difluoroethoxy)-N-(5,8-dimethoxy-[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide Penoxsulam C16H14F5N5O5S COC1=CN=C(N2C1=NC(=N2)NS(=O)(=O)C3=C(C=CC=C3OCC(F)F)C(F)(F)F)OC InChI=1S/C16H14F5N5O5S/c1-29-10-6-22-15(30-2)26-13(10)23-14(24-26)25-32(27,28)12-8(16(19,20)21)4-3-5-9(12)31-7-11(17)18/h3-6,11H,7H2,1-2H3,(H,24,25) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Rat (as animal) lymphocytes Not reported yes with Negative RMS: Italy Penoxsulam (DE-638) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance penoxsulam 22Sep2009 2009 doi:10.2903/j.efsa.2009.343r
+Penoxsulam 219714-96-2 single chemical entity Component is identical to the substance Penoxsulam (DE 638) 219714-96-2 2-(2,2-difluoroethoxy)-N-(5,8-dimethoxy-[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide Penoxsulam C16H14F5N5O5S COC1=CN=C(N2C1=NC(=N2)NS(=O)(=O)C3=C(C=CC=C3OCC(F)F)C(F)(F)F)OC InChI=1S/C16H14F5N5O5S/c1-29-10-6-22-15(30-2)26-13(10)23-14(24-26)25-32(27,28)12-8(16(19,20)21)4-3-5-9(12)31-7-11(17)18/h3-6,11H,7H2,1-2H3,(H,24,25) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Italy Penoxsulam (DE-638) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance penoxsulam 22Sep2009 2009 doi:10.2903/j.efsa.2009.343r
+Penoxsulam 219714-96-2 single chemical entity Component is identical to the substance Penoxsulam (DE 638) 219714-96-2 2-(2,2-difluoroethoxy)-N-(5,8-dimethoxy-[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide Penoxsulam C16H14F5N5O5S COC1=CN=C(N2C1=NC(=N2)NS(=O)(=O)C3=C(C=CC=C3OCC(F)F)C(F)(F)F)OC InChI=1S/C16H14F5N5O5S/c1-29-10-6-22-15(30-2)26-13(10)23-14(24-26)25-32(27,28)12-8(16(19,20)21)4-3-5-9(12)31-7-11(17)18/h3-6,11H,7H2,1-2H3,(H,24,25) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Italy Penoxsulam (DE-638) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance penoxsulam 22Sep2009 2009 doi:10.2903/j.efsa.2009.343r
+Penoxsulam 219714-96-2 single chemical entity Component is identical to the substance Penoxsulam (DE 638) 219714-96-2 2-(2,2-difluoroethoxy)-N-(5,8-dimethoxy-[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide Penoxsulam C16H14F5N5O5S COC1=CN=C(N2C1=NC(=N2)NS(=O)(=O)C3=C(C=CC=C3OCC(F)F)C(F)(F)F)OC InChI=1S/C16H14F5N5O5S/c1-29-10-6-22-15(30-2)26-13(10)23-14(24-26)25-32(27,28)12-8(16(19,20)21)4-3-5-9(12)31-7-11(17)18/h3-6,11H,7H2,1-2H3,(H,24,25) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 5 Male oral: gavage 24.0000000000 h yes not applicable Negative no evidence RMS: Italy Penoxsulam (DE-638) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance penoxsulam 22Sep2009 2009 doi:10.2903/j.efsa.2009.343r
+Penoxsulam 219714-96-2 single chemical entity Component is a metabolite of the substance 2-(2,2-Difluoroethoxy)-N-(5-hydroxy-8-methoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide 2-(2,2-difluoroethoxy)-N-(5-hydroxy-8-methoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide Not in list C15H12F5N5O5S FC(F)(F)c1cccc(OCC(F)F)c1S(=O)(=O)Nc2nc3c(cnc(O)n3n2)OC InChI=1S/C15H12F5N5O5S/c1-29-9-5-21-14(26)25-12(9)22-13(23-25)24-31(27,28)11-7(15(18,19)20)3-2-4-8(11)30-6-10(16)17/h2-5,10H,6H2,1H3,(H,21,26)(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Italy Penoxsulam (Final Addendum to the DAR) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance penoxsulam 22Sep2009 2009 doi:10.2903/j.efsa.2009.343r
+Penoxsulam 219714-96-2 single chemical entity Component is a metabolite of the substance 2-(2,2-Difluoroethoxy)-N-(5-hydroxy-8-methoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide 2-(2,2-difluoroethoxy)-N-(5-hydroxy-8-methoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide Not in list C15H12F5N5O5S FC(F)(F)c1cccc(OCC(F)F)c1S(=O)(=O)Nc2nc3c(cnc(O)n3n2)OC InChI=1S/C15H12F5N5O5S/c1-29-9-5-21-14(26)25-12(9)22-13(23-25)24-31(27,28)11-7(15(18,19)20)3-2-4-8(11)30-6-10(16)17/h2-5,10H,6H2,1H3,(H,21,26)(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Italy Penoxsulam (Final Addendum to the DAR) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance penoxsulam 22Sep2009 2009 doi:10.2903/j.efsa.2009.343r
+Penoxsulam 219714-96-2 single chemical entity Component is a metabolite of the substance 2-(2,2-Difluoroethoxy)-N-(5-hydroxy-8-methoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide 2-(2,2-difluoroethoxy)-N-(5-hydroxy-8-methoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide Not in list C15H12F5N5O5S FC(F)(F)c1cccc(OCC(F)F)c1S(=O)(=O)Nc2nc3c(cnc(O)n3n2)OC InChI=1S/C15H12F5N5O5S/c1-29-9-5-21-14(26)25-12(9)22-13(23-25)24-31(27,28)11-7(15(18,19)20)3-2-4-8(11)30-6-10(16)17/h2-5,10H,6H2,1H3,(H,21,26)(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Italy Penoxsulam (Final Addendum to the DAR) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance penoxsulam 22Sep2009 2009 doi:10.2903/j.efsa.2009.343r
+Penoxsulam 219714-96-2 single chemical entity Component is a metabolite of the substance 2-(2,2-Difluoroethoxy)-N-(5-hydroxy-8-methoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide 2-(2,2-difluoroethoxy)-N-(5-hydroxy-8-methoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide Not in list C15H12F5N5O5S FC(F)(F)c1cccc(OCC(F)F)c1S(=O)(=O)Nc2nc3c(cnc(O)n3n2)OC InChI=1S/C15H12F5N5O5S/c1-29-9-5-21-14(26)25-12(9)22-13(23-25)24-31(27,28)11-7(15(18,19)20)3-2-4-8(11)30-6-10(16)17/h2-5,10H,6H2,1H3,(H,21,26)(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Italy Penoxsulam (Final Addendum to the DAR) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance penoxsulam 22Sep2009 2009 doi:10.2903/j.efsa.2009.343r
+Penoxsulam 219714-96-2 single chemical entity Component is a metabolite of the substance 2-(2,2-Difluoroethoxy)-N-(5-hydroxy-8-methoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide 2-(2,2-difluoroethoxy)-N-(5-hydroxy-8-methoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide Not in list C15H12F5N5O5S FC(F)(F)c1cccc(OCC(F)F)c1S(=O)(=O)Nc2nc3c(cnc(O)n3n2)OC InChI=1S/C15H12F5N5O5S/c1-29-9-5-21-14(26)25-12(9)22-13(23-25)24-31(27,28)11-7(15(18,19)20)3-2-4-8(11)30-6-10(16)17/h2-5,10H,6H2,1H3,(H,21,26)(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Italy Penoxsulam (Final Addendum to the DAR) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance penoxsulam 22Sep2009 2009 doi:10.2903/j.efsa.2009.343r
+Penoxsulam 219714-96-2 single chemical entity Component is a metabolite of the substance 2-(2,2-Difluoroethoxy)-N-(5-hydroxy-8-methoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide 2-(2,2-difluoroethoxy)-N-(5-hydroxy-8-methoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide Not in list C15H12F5N5O5S FC(F)(F)c1cccc(OCC(F)F)c1S(=O)(=O)Nc2nc3c(cnc(O)n3n2)OC InChI=1S/C15H12F5N5O5S/c1-29-9-5-21-14(26)25-12(9)22-13(23-25)24-31(27,28)11-7(15(18,19)20)3-2-4-8(11)30-6-10(16)17/h2-5,10H,6H2,1H3,(H,21,26)(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Italy Penoxsulam (Final Addendum to the DAR) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance penoxsulam 22Sep2009 2009 doi:10.2903/j.efsa.2009.343r
+Penoxsulam 219714-96-2 single chemical entity Component is a metabolite of the substance 2-(2,2-Difluoroethoxy)-N-(5-hydroxy-8-methoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide 2-(2,2-difluoroethoxy)-N-(5-hydroxy-8-methoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide Not in list C15H12F5N5O5S FC(F)(F)c1cccc(OCC(F)F)c1S(=O)(=O)Nc2nc3c(cnc(O)n3n2)OC InChI=1S/C15H12F5N5O5S/c1-29-9-5-21-14(26)25-12(9)22-13(23-25)24-31(27,28)11-7(15(18,19)20)3-2-4-8(11)30-6-10(16)17/h2-5,10H,6H2,1H3,(H,21,26)(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Italy Penoxsulam (Final Addendum to the DAR) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance penoxsulam 22Sep2009 2009 doi:10.2903/j.efsa.2009.343r
+Penoxsulam 219714-96-2 single chemical entity Component is a metabolite of the substance 2-(2,2-Difluoroethoxy)-N-(5-hydroxy-8-methoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide 2-(2,2-difluoroethoxy)-N-(5-hydroxy-8-methoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide Not in list C15H12F5N5O5S FC(F)(F)c1cccc(OCC(F)F)c1S(=O)(=O)Nc2nc3c(cnc(O)n3n2)OC InChI=1S/C15H12F5N5O5S/c1-29-9-5-21-14(26)25-12(9)22-13(23-25)24-31(27,28)11-7(15(18,19)20)3-2-4-8(11)30-6-10(16)17/h2-5,10H,6H2,1H3,(H,21,26)(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Italy Penoxsulam (Final Addendum to the DAR) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance penoxsulam 22Sep2009 2009 doi:10.2903/j.efsa.2009.343r
+Penoxsulam 219714-96-2 single chemical entity Component is a metabolite of the substance 2-(2,2-Difluoroethoxy)-N-(5-hydroxy-8-methoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide 2-(2,2-difluoroethoxy)-N-(5-hydroxy-8-methoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide Not in list C15H12F5N5O5S FC(F)(F)c1cccc(OCC(F)F)c1S(=O)(=O)Nc2nc3c(cnc(O)n3n2)OC InChI=1S/C15H12F5N5O5S/c1-29-9-5-21-14(26)25-12(9)22-13(23-25)24-31(27,28)11-7(15(18,19)20)3-2-4-8(11)30-6-10(16)17/h2-5,10H,6H2,1H3,(H,21,26)(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Italy Penoxsulam (Final Addendum to the DAR) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance penoxsulam 22Sep2009 2009 doi:10.2903/j.efsa.2009.343r
+Penoxsulam 219714-96-2 single chemical entity Component is a metabolite of the substance 2-(2,2-Difluoroethoxy)-N-(5-hydroxy-8-methoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide 2-(2,2-difluoroethoxy)-N-(5-hydroxy-8-methoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide Not in list C15H12F5N5O5S FC(F)(F)c1cccc(OCC(F)F)c1S(=O)(=O)Nc2nc3c(cnc(O)n3n2)OC InChI=1S/C15H12F5N5O5S/c1-29-9-5-21-14(26)25-12(9)22-13(23-25)24-31(27,28)11-7(15(18,19)20)3-2-4-8(11)30-6-10(16)17/h2-5,10H,6H2,1H3,(H,21,26)(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Italy Penoxsulam (Final Addendum to the DAR) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance penoxsulam 22Sep2009 2009 doi:10.2903/j.efsa.2009.343r
+Penoxsulam 219714-96-2 single chemical entity Component is a metabolite of the substance 2-(2,2-Difluoroethoxy)-N-(5-hydroxy-8-methoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide 2-(2,2-difluoroethoxy)-N-(5-hydroxy-8-methoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide Not in list C15H12F5N5O5S FC(F)(F)c1cccc(OCC(F)F)c1S(=O)(=O)Nc2nc3c(cnc(O)n3n2)OC InChI=1S/C15H12F5N5O5S/c1-29-9-5-21-14(26)25-12(9)22-13(23-25)24-31(27,28)11-7(15(18,19)20)3-2-4-8(11)30-6-10(16)17/h2-5,10H,6H2,1H3,(H,21,26)(H,23,24) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Italy Penoxsulam (Final Addendum to the DAR) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance penoxsulam 22Sep2009 2009 doi:10.2903/j.efsa.2009.343r
+Penoxsulam 219714-96-2 single chemical entity Component is a metabolite of the substance 2-(2,2-Difluoroethoxy)-N-(5-hydroxy-8-methoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide 2-(2,2-difluoroethoxy)-N-(5-hydroxy-8-methoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide Not in list C15H12F5N5O5S FC(F)(F)c1cccc(OCC(F)F)c1S(=O)(=O)Nc2nc3c(cnc(O)n3n2)OC InChI=1S/C15H12F5N5O5S/c1-29-9-5-21-14(26)25-12(9)22-13(23-25)24-31(27,28)11-7(15(18,19)20)3-2-4-8(11)30-6-10(16)17/h2-5,10H,6H2,1H3,(H,21,26)(H,23,24) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Italy Penoxsulam (Final Addendum to the DAR) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance penoxsulam 22Sep2009 2009 doi:10.2903/j.efsa.2009.343r
+Penoxsulam 219714-96-2 single chemical entity Component is a metabolite of the substance 2-(2,2-Difluoroethoxy)-N-(5-hydroxy-8-methoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide 2-(2,2-difluoroethoxy)-N-(5-hydroxy-8-methoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide Not in list C15H12F5N5O5S FC(F)(F)c1cccc(OCC(F)F)c1S(=O)(=O)Nc2nc3c(cnc(O)n3n2)OC InChI=1S/C15H12F5N5O5S/c1-29-9-5-21-14(26)25-12(9)22-13(23-25)24-31(27,28)11-7(15(18,19)20)3-2-4-8(11)30-6-10(16)17/h2-5,10H,6H2,1H3,(H,21,26)(H,23,24) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Rat (as animal) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Italy Penoxsulam (Final Addendum to the DAR) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance penoxsulam 22Sep2009 2009 doi:10.2903/j.efsa.2009.343r
+Penoxsulam 219714-96-2 single chemical entity Component is a metabolite of the substance 2-(2,2-Difluoroethoxy)-N-(5-hydroxy-8-methoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide 2-(2,2-difluoroethoxy)-N-(5-hydroxy-8-methoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide Not in list C15H12F5N5O5S FC(F)(F)c1cccc(OCC(F)F)c1S(=O)(=O)Nc2nc3c(cnc(O)n3n2)OC InChI=1S/C15H12F5N5O5S/c1-29-9-5-21-14(26)25-12(9)22-13(23-25)24-31(27,28)11-7(15(18,19)20)3-2-4-8(11)30-6-10(16)17/h2-5,10H,6H2,1H3,(H,21,26)(H,23,24) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Rat (as animal) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Italy Penoxsulam (Final Addendum to the DAR) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance penoxsulam 22Sep2009 2009 doi:10.2903/j.efsa.2009.343r
+Penoxsulam 219714-96-2 single chemical entity Component is a metabolite of the substance 3-({[2-(2,2-Difluoroethoxy)-6-(trifluoromethyl)phenyl]sulfonyl}amino)-1H-1,2,4-triazole-5-carboxylic acid 3-({[2-(2,2-difluoroethoxy)-6-(trifluoromethyl)phenyl]sulfonyl}amino)-1H-1,2,4-triazole-5-carboxylic acid Not in list C11H9F5N4O5S OC(=O)c1nnc(NS(=O)(=O)c2c(OCC(F)F)cccc2C(F)(F)F)[nH]1 InChI=1S/C12H9F5N4O5S/c13-7(14)4-26-6-3-1-2-5(12(15,16)17)8(6)27(24,25)21-11-18-9(10(22)23)19-20-11/h1-3,7H,4H2,(H,22,23)(H2,18,19,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Italy Penoxsulam (Final Addendum to the DAR) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance penoxsulam 22Sep2009 2009 doi:10.2903/j.efsa.2009.343r
+Penoxsulam 219714-96-2 single chemical entity Component is a metabolite of the substance 3-({[2-(2,2-Difluoroethoxy)-6-(trifluoromethyl)phenyl]sulfonyl}amino)-1H-1,2,4-triazole-5-carboxylic acid 3-({[2-(2,2-difluoroethoxy)-6-(trifluoromethyl)phenyl]sulfonyl}amino)-1H-1,2,4-triazole-5-carboxylic acid Not in list C11H9F5N4O5S OC(=O)c1nnc(NS(=O)(=O)c2c(OCC(F)F)cccc2C(F)(F)F)[nH]1 InChI=1S/C12H9F5N4O5S/c13-7(14)4-26-6-3-1-2-5(12(15,16)17)8(6)27(24,25)21-11-18-9(10(22)23)19-20-11/h1-3,7H,4H2,(H,22,23)(H2,18,19,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Italy Penoxsulam (Final Addendum to the DAR) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance penoxsulam 22Sep2009 2009 doi:10.2903/j.efsa.2009.343r
+Penoxsulam 219714-96-2 single chemical entity Component is a metabolite of the substance 3-({[2-(2,2-Difluoroethoxy)-6-(trifluoromethyl)phenyl]sulfonyl}amino)-1H-1,2,4-triazole-5-carboxylic acid 3-({[2-(2,2-difluoroethoxy)-6-(trifluoromethyl)phenyl]sulfonyl}amino)-1H-1,2,4-triazole-5-carboxylic acid Not in list C11H9F5N4O5S OC(=O)c1nnc(NS(=O)(=O)c2c(OCC(F)F)cccc2C(F)(F)F)[nH]1 InChI=1S/C12H9F5N4O5S/c13-7(14)4-26-6-3-1-2-5(12(15,16)17)8(6)27(24,25)21-11-18-9(10(22)23)19-20-11/h1-3,7H,4H2,(H,22,23)(H2,18,19,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Italy Penoxsulam (Final Addendum to the DAR) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance penoxsulam 22Sep2009 2009 doi:10.2903/j.efsa.2009.343r
+Penoxsulam 219714-96-2 single chemical entity Component is a metabolite of the substance 3-({[2-(2,2-Difluoroethoxy)-6-(trifluoromethyl)phenyl]sulfonyl}amino)-1H-1,2,4-triazole-5-carboxylic acid 3-({[2-(2,2-difluoroethoxy)-6-(trifluoromethyl)phenyl]sulfonyl}amino)-1H-1,2,4-triazole-5-carboxylic acid Not in list C11H9F5N4O5S OC(=O)c1nnc(NS(=O)(=O)c2c(OCC(F)F)cccc2C(F)(F)F)[nH]1 InChI=1S/C12H9F5N4O5S/c13-7(14)4-26-6-3-1-2-5(12(15,16)17)8(6)27(24,25)21-11-18-9(10(22)23)19-20-11/h1-3,7H,4H2,(H,22,23)(H2,18,19,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Italy Penoxsulam (Final Addendum to the DAR) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance penoxsulam 22Sep2009 2009 doi:10.2903/j.efsa.2009.343r
+Penoxsulam 219714-96-2 single chemical entity Component is a metabolite of the substance 3-({[2-(2,2-Difluoroethoxy)-6-(trifluoromethyl)phenyl]sulfonyl}amino)-1H-1,2,4-triazole-5-carboxylic acid 3-({[2-(2,2-difluoroethoxy)-6-(trifluoromethyl)phenyl]sulfonyl}amino)-1H-1,2,4-triazole-5-carboxylic acid Not in list C11H9F5N4O5S OC(=O)c1nnc(NS(=O)(=O)c2c(OCC(F)F)cccc2C(F)(F)F)[nH]1 InChI=1S/C12H9F5N4O5S/c13-7(14)4-26-6-3-1-2-5(12(15,16)17)8(6)27(24,25)21-11-18-9(10(22)23)19-20-11/h1-3,7H,4H2,(H,22,23)(H2,18,19,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Italy Penoxsulam (Final Addendum to the DAR) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance penoxsulam 22Sep2009 2009 doi:10.2903/j.efsa.2009.343r
+Penoxsulam 219714-96-2 single chemical entity Component is a metabolite of the substance 3-({[2-(2,2-Difluoroethoxy)-6-(trifluoromethyl)phenyl]sulfonyl}amino)-1H-1,2,4-triazole-5-carboxylic acid 3-({[2-(2,2-difluoroethoxy)-6-(trifluoromethyl)phenyl]sulfonyl}amino)-1H-1,2,4-triazole-5-carboxylic acid Not in list C11H9F5N4O5S OC(=O)c1nnc(NS(=O)(=O)c2c(OCC(F)F)cccc2C(F)(F)F)[nH]1 InChI=1S/C12H9F5N4O5S/c13-7(14)4-26-6-3-1-2-5(12(15,16)17)8(6)27(24,25)21-11-18-9(10(22)23)19-20-11/h1-3,7H,4H2,(H,22,23)(H2,18,19,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Italy Penoxsulam (Final Addendum to the DAR) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance penoxsulam 22Sep2009 2009 doi:10.2903/j.efsa.2009.343r
+Penoxsulam 219714-96-2 single chemical entity Component is a metabolite of the substance 3-({[2-(2,2-Difluoroethoxy)-6-(trifluoromethyl)phenyl]sulfonyl}amino)-1H-1,2,4-triazole-5-carboxylic acid 3-({[2-(2,2-difluoroethoxy)-6-(trifluoromethyl)phenyl]sulfonyl}amino)-1H-1,2,4-triazole-5-carboxylic acid Not in list C11H9F5N4O5S OC(=O)c1nnc(NS(=O)(=O)c2c(OCC(F)F)cccc2C(F)(F)F)[nH]1 InChI=1S/C12H9F5N4O5S/c13-7(14)4-26-6-3-1-2-5(12(15,16)17)8(6)27(24,25)21-11-18-9(10(22)23)19-20-11/h1-3,7H,4H2,(H,22,23)(H2,18,19,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Italy Penoxsulam (Final Addendum to the DAR) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance penoxsulam 22Sep2009 2009 doi:10.2903/j.efsa.2009.343r
+Penoxsulam 219714-96-2 single chemical entity Component is a metabolite of the substance 3-({[2-(2,2-Difluoroethoxy)-6-(trifluoromethyl)phenyl]sulfonyl}amino)-1H-1,2,4-triazole-5-carboxylic acid 3-({[2-(2,2-difluoroethoxy)-6-(trifluoromethyl)phenyl]sulfonyl}amino)-1H-1,2,4-triazole-5-carboxylic acid Not in list C11H9F5N4O5S OC(=O)c1nnc(NS(=O)(=O)c2c(OCC(F)F)cccc2C(F)(F)F)[nH]1 InChI=1S/C12H9F5N4O5S/c13-7(14)4-26-6-3-1-2-5(12(15,16)17)8(6)27(24,25)21-11-18-9(10(22)23)19-20-11/h1-3,7H,4H2,(H,22,23)(H2,18,19,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Italy Penoxsulam (Final Addendum to the DAR) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance penoxsulam 22Sep2009 2009 doi:10.2903/j.efsa.2009.343r
+Penoxsulam 219714-96-2 single chemical entity Component is a metabolite of the substance 3-({[2-(2,2-Difluoroethoxy)-6-(trifluoromethyl)phenyl]sulfonyl}amino)-1H-1,2,4-triazole-5-carboxylic acid 3-({[2-(2,2-difluoroethoxy)-6-(trifluoromethyl)phenyl]sulfonyl}amino)-1H-1,2,4-triazole-5-carboxylic acid Not in list C11H9F5N4O5S OC(=O)c1nnc(NS(=O)(=O)c2c(OCC(F)F)cccc2C(F)(F)F)[nH]1 InChI=1S/C12H9F5N4O5S/c13-7(14)4-26-6-3-1-2-5(12(15,16)17)8(6)27(24,25)21-11-18-9(10(22)23)19-20-11/h1-3,7H,4H2,(H,22,23)(H2,18,19,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Italy Penoxsulam (Final Addendum to the DAR) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance penoxsulam 22Sep2009 2009 doi:10.2903/j.efsa.2009.343r
+Penoxsulam 219714-96-2 single chemical entity Component is a metabolite of the substance 3-({[2-(2,2-Difluoroethoxy)-6-(trifluoromethyl)phenyl]sulfonyl}amino)-1H-1,2,4-triazole-5-carboxylic acid 3-({[2-(2,2-difluoroethoxy)-6-(trifluoromethyl)phenyl]sulfonyl}amino)-1H-1,2,4-triazole-5-carboxylic acid Not in list C11H9F5N4O5S OC(=O)c1nnc(NS(=O)(=O)c2c(OCC(F)F)cccc2C(F)(F)F)[nH]1 InChI=1S/C12H9F5N4O5S/c13-7(14)4-26-6-3-1-2-5(12(15,16)17)8(6)27(24,25)21-11-18-9(10(22)23)19-20-11/h1-3,7H,4H2,(H,22,23)(H2,18,19,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Italy Penoxsulam (Final Addendum to the DAR) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance penoxsulam 22Sep2009 2009 doi:10.2903/j.efsa.2009.343r
+Penoxsulam 219714-96-2 single chemical entity Component is a metabolite of the substance 3-({[2-(2,2-Difluoroethoxy)-6-(trifluoromethyl)phenyl]sulfonyl}amino)-1H-1,2,4-triazole-5-carboxylic acid 3-({[2-(2,2-difluoroethoxy)-6-(trifluoromethyl)phenyl]sulfonyl}amino)-1H-1,2,4-triazole-5-carboxylic acid Not in list C11H9F5N4O5S OC(=O)c1nnc(NS(=O)(=O)c2c(OCC(F)F)cccc2C(F)(F)F)[nH]1 InChI=1S/C12H9F5N4O5S/c13-7(14)4-26-6-3-1-2-5(12(15,16)17)8(6)27(24,25)21-11-18-9(10(22)23)19-20-11/h1-3,7H,4H2,(H,22,23)(H2,18,19,20,21) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Italy Penoxsulam (Final Addendum to the DAR) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance penoxsulam 22Sep2009 2009 doi:10.2903/j.efsa.2009.343r
+Penoxsulam 219714-96-2 single chemical entity Component is a metabolite of the substance 3-({[2-(2,2-Difluoroethoxy)-6-(trifluoromethyl)phenyl]sulfonyl}amino)-1H-1,2,4-triazole-5-carboxylic acid 3-({[2-(2,2-difluoroethoxy)-6-(trifluoromethyl)phenyl]sulfonyl}amino)-1H-1,2,4-triazole-5-carboxylic acid Not in list C11H9F5N4O5S OC(=O)c1nnc(NS(=O)(=O)c2c(OCC(F)F)cccc2C(F)(F)F)[nH]1 InChI=1S/C12H9F5N4O5S/c13-7(14)4-26-6-3-1-2-5(12(15,16)17)8(6)27(24,25)21-11-18-9(10(22)23)19-20-11/h1-3,7H,4H2,(H,22,23)(H2,18,19,20,21) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Italy Penoxsulam (Final Addendum to the DAR) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance penoxsulam 22Sep2009 2009 doi:10.2903/j.efsa.2009.343r
+Penoxsulam 219714-96-2 single chemical entity Component is a metabolite of the substance 3-({[2-(2,2-Difluoroethoxy)-6-(trifluoromethyl)phenyl]sulfonyl}amino)-1H-1,2,4-triazole-5-carboxylic acid 3-({[2-(2,2-difluoroethoxy)-6-(trifluoromethyl)phenyl]sulfonyl}amino)-1H-1,2,4-triazole-5-carboxylic acid Not in list C11H9F5N4O5S OC(=O)c1nnc(NS(=O)(=O)c2c(OCC(F)F)cccc2C(F)(F)F)[nH]1 InChI=1S/C12H9F5N4O5S/c13-7(14)4-26-6-3-1-2-5(12(15,16)17)8(6)27(24,25)21-11-18-9(10(22)23)19-20-11/h1-3,7H,4H2,(H,22,23)(H2,18,19,20,21) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Rat (as animal) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Italy Penoxsulam (Final Addendum to the DAR) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance penoxsulam 22Sep2009 2009 doi:10.2903/j.efsa.2009.343r
+Penoxsulam 219714-96-2 single chemical entity Component is a metabolite of the substance 3-({[2-(2,2-Difluoroethoxy)-6-(trifluoromethyl)phenyl]sulfonyl}amino)-1H-1,2,4-triazole-5-carboxylic acid 3-({[2-(2,2-difluoroethoxy)-6-(trifluoromethyl)phenyl]sulfonyl}amino)-1H-1,2,4-triazole-5-carboxylic acid Not in list C11H9F5N4O5S OC(=O)c1nnc(NS(=O)(=O)c2c(OCC(F)F)cccc2C(F)(F)F)[nH]1 InChI=1S/C12H9F5N4O5S/c13-7(14)4-26-6-3-1-2-5(12(15,16)17)8(6)27(24,25)21-11-18-9(10(22)23)19-20-11/h1-3,7H,4H2,(H,22,23)(H2,18,19,20,21) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Rat (as animal) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Italy Penoxsulam (Final Addendum to the DAR) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance penoxsulam 22Sep2009 2009 doi:10.2903/j.efsa.2009.343r
+Penoxsulam 219714-96-2 single chemical entity Component is a metabolite of the substance 2-(2,2-Difluoroethoxy)-N-(1H-1,2,4-triazol-3-yl)-6-(trifluoromethyl)benzenesulfonamide 2-(2,2-difluoroethoxy)-N-(1H-1,2,4-triazol-3-yl)-6-(trifluoromethyl)benzenesulfonamide Not in list C11H9F5N4O3S O=S(=O)(Nc1ncnn1)c2c(cccc2OCC(F)F)C(F)(F)F InChI=1/C11H9F5N4O3S/c12-8(13)4-23-7-3-1-2-6(11(14,15)16)9(7)24(21,22)20-10-17-5-18-19-10/h1-3,5,8H,4H2,(H2,17,18,19,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Italy Penoxsulam (Final Addendum to the DAR) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance penoxsulam 22Sep2009 2009 doi:10.2903/j.efsa.2009.343r
+Penoxsulam 219714-96-2 single chemical entity Component is a metabolite of the substance 2-(2,2-Difluoroethoxy)-N-(1H-1,2,4-triazol-3-yl)-6-(trifluoromethyl)benzenesulfonamide 2-(2,2-difluoroethoxy)-N-(1H-1,2,4-triazol-3-yl)-6-(trifluoromethyl)benzenesulfonamide Not in list C11H9F5N4O3S O=S(=O)(Nc1ncnn1)c2c(cccc2OCC(F)F)C(F)(F)F InChI=1/C11H9F5N4O3S/c12-8(13)4-23-7-3-1-2-6(11(14,15)16)9(7)24(21,22)20-10-17-5-18-19-10/h1-3,5,8H,4H2,(H2,17,18,19,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Italy Penoxsulam (Final Addendum to the DAR) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance penoxsulam 22Sep2009 2009 doi:10.2903/j.efsa.2009.343r
+Penoxsulam 219714-96-2 single chemical entity Component is a metabolite of the substance 2-(2,2-Difluoroethoxy)-N-(1H-1,2,4-triazol-3-yl)-6-(trifluoromethyl)benzenesulfonamide 2-(2,2-difluoroethoxy)-N-(1H-1,2,4-triazol-3-yl)-6-(trifluoromethyl)benzenesulfonamide Not in list C11H9F5N4O3S O=S(=O)(Nc1ncnn1)c2c(cccc2OCC(F)F)C(F)(F)F InChI=1/C11H9F5N4O3S/c12-8(13)4-23-7-3-1-2-6(11(14,15)16)9(7)24(21,22)20-10-17-5-18-19-10/h1-3,5,8H,4H2,(H2,17,18,19,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Italy Penoxsulam (Final Addendum to the DAR) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance penoxsulam 22Sep2009 2009 doi:10.2903/j.efsa.2009.343r
+Penoxsulam 219714-96-2 single chemical entity Component is a metabolite of the substance 2-(2,2-Difluoroethoxy)-N-(1H-1,2,4-triazol-3-yl)-6-(trifluoromethyl)benzenesulfonamide 2-(2,2-difluoroethoxy)-N-(1H-1,2,4-triazol-3-yl)-6-(trifluoromethyl)benzenesulfonamide Not in list C11H9F5N4O3S O=S(=O)(Nc1ncnn1)c2c(cccc2OCC(F)F)C(F)(F)F InChI=1/C11H9F5N4O3S/c12-8(13)4-23-7-3-1-2-6(11(14,15)16)9(7)24(21,22)20-10-17-5-18-19-10/h1-3,5,8H,4H2,(H2,17,18,19,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Italy Penoxsulam (Final Addendum to the DAR) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance penoxsulam 22Sep2009 2009 doi:10.2903/j.efsa.2009.343r
+Penoxsulam 219714-96-2 single chemical entity Component is a metabolite of the substance 2-(2,2-Difluoroethoxy)-N-(1H-1,2,4-triazol-3-yl)-6-(trifluoromethyl)benzenesulfonamide 2-(2,2-difluoroethoxy)-N-(1H-1,2,4-triazol-3-yl)-6-(trifluoromethyl)benzenesulfonamide Not in list C11H9F5N4O3S O=S(=O)(Nc1ncnn1)c2c(cccc2OCC(F)F)C(F)(F)F InChI=1/C11H9F5N4O3S/c12-8(13)4-23-7-3-1-2-6(11(14,15)16)9(7)24(21,22)20-10-17-5-18-19-10/h1-3,5,8H,4H2,(H2,17,18,19,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Italy Penoxsulam (Final Addendum to the DAR) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance penoxsulam 22Sep2009 2009 doi:10.2903/j.efsa.2009.343r
+Penoxsulam 219714-96-2 single chemical entity Component is a metabolite of the substance 2-(2,2-Difluoroethoxy)-N-(1H-1,2,4-triazol-3-yl)-6-(trifluoromethyl)benzenesulfonamide 2-(2,2-difluoroethoxy)-N-(1H-1,2,4-triazol-3-yl)-6-(trifluoromethyl)benzenesulfonamide Not in list C11H9F5N4O3S O=S(=O)(Nc1ncnn1)c2c(cccc2OCC(F)F)C(F)(F)F InChI=1/C11H9F5N4O3S/c12-8(13)4-23-7-3-1-2-6(11(14,15)16)9(7)24(21,22)20-10-17-5-18-19-10/h1-3,5,8H,4H2,(H2,17,18,19,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Italy Penoxsulam (Final Addendum to the DAR) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance penoxsulam 22Sep2009 2009 doi:10.2903/j.efsa.2009.343r
+Penoxsulam 219714-96-2 single chemical entity Component is a metabolite of the substance 2-(2,2-Difluoroethoxy)-N-(1H-1,2,4-triazol-3-yl)-6-(trifluoromethyl)benzenesulfonamide 2-(2,2-difluoroethoxy)-N-(1H-1,2,4-triazol-3-yl)-6-(trifluoromethyl)benzenesulfonamide Not in list C11H9F5N4O3S O=S(=O)(Nc1ncnn1)c2c(cccc2OCC(F)F)C(F)(F)F InChI=1/C11H9F5N4O3S/c12-8(13)4-23-7-3-1-2-6(11(14,15)16)9(7)24(21,22)20-10-17-5-18-19-10/h1-3,5,8H,4H2,(H2,17,18,19,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Italy Penoxsulam (Final Addendum to the DAR) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance penoxsulam 22Sep2009 2009 doi:10.2903/j.efsa.2009.343r
+Penoxsulam 219714-96-2 single chemical entity Component is a metabolite of the substance 2-(2,2-Difluoroethoxy)-N-(1H-1,2,4-triazol-3-yl)-6-(trifluoromethyl)benzenesulfonamide 2-(2,2-difluoroethoxy)-N-(1H-1,2,4-triazol-3-yl)-6-(trifluoromethyl)benzenesulfonamide Not in list C11H9F5N4O3S O=S(=O)(Nc1ncnn1)c2c(cccc2OCC(F)F)C(F)(F)F InChI=1/C11H9F5N4O3S/c12-8(13)4-23-7-3-1-2-6(11(14,15)16)9(7)24(21,22)20-10-17-5-18-19-10/h1-3,5,8H,4H2,(H2,17,18,19,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Italy Penoxsulam (Final Addendum to the DAR) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance penoxsulam 22Sep2009 2009 doi:10.2903/j.efsa.2009.343r
+Penoxsulam 219714-96-2 single chemical entity Component is a metabolite of the substance 2-(2,2-Difluoroethoxy)-N-(1H-1,2,4-triazol-3-yl)-6-(trifluoromethyl)benzenesulfonamide 2-(2,2-difluoroethoxy)-N-(1H-1,2,4-triazol-3-yl)-6-(trifluoromethyl)benzenesulfonamide Not in list C11H9F5N4O3S O=S(=O)(Nc1ncnn1)c2c(cccc2OCC(F)F)C(F)(F)F InChI=1/C11H9F5N4O3S/c12-8(13)4-23-7-3-1-2-6(11(14,15)16)9(7)24(21,22)20-10-17-5-18-19-10/h1-3,5,8H,4H2,(H2,17,18,19,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Italy Penoxsulam (Final Addendum to the DAR) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance penoxsulam 22Sep2009 2009 doi:10.2903/j.efsa.2009.343r
+Penoxsulam 219714-96-2 single chemical entity Component is a metabolite of the substance 2-(2,2-Difluoroethoxy)-N-(1H-1,2,4-triazol-3-yl)-6-(trifluoromethyl)benzenesulfonamide 2-(2,2-difluoroethoxy)-N-(1H-1,2,4-triazol-3-yl)-6-(trifluoromethyl)benzenesulfonamide Not in list C11H9F5N4O3S O=S(=O)(Nc1ncnn1)c2c(cccc2OCC(F)F)C(F)(F)F InChI=1/C11H9F5N4O3S/c12-8(13)4-23-7-3-1-2-6(11(14,15)16)9(7)24(21,22)20-10-17-5-18-19-10/h1-3,5,8H,4H2,(H2,17,18,19,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Italy Penoxsulam (Final Addendum to the DAR) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance penoxsulam 22Sep2009 2009 doi:10.2903/j.efsa.2009.343r
+Penoxsulam 219714-96-2 single chemical entity Component is a metabolite of the substance 2-(2,2-Difluoroethoxy)-N-(1H-1,2,4-triazol-3-yl)-6-(trifluoromethyl)benzenesulfonamide 2-(2,2-difluoroethoxy)-N-(1H-1,2,4-triazol-3-yl)-6-(trifluoromethyl)benzenesulfonamide Not in list C11H9F5N4O3S O=S(=O)(Nc1ncnn1)c2c(cccc2OCC(F)F)C(F)(F)F InChI=1/C11H9F5N4O3S/c12-8(13)4-23-7-3-1-2-6(11(14,15)16)9(7)24(21,22)20-10-17-5-18-19-10/h1-3,5,8H,4H2,(H2,17,18,19,20) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Italy Penoxsulam (Final Addendum to the DAR) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance penoxsulam 22Sep2009 2009 doi:10.2903/j.efsa.2009.343r
+Penoxsulam 219714-96-2 single chemical entity Component is a metabolite of the substance 2-(2,2-Difluoroethoxy)-N-(1H-1,2,4-triazol-3-yl)-6-(trifluoromethyl)benzenesulfonamide 2-(2,2-difluoroethoxy)-N-(1H-1,2,4-triazol-3-yl)-6-(trifluoromethyl)benzenesulfonamide Not in list C11H9F5N4O3S O=S(=O)(Nc1ncnn1)c2c(cccc2OCC(F)F)C(F)(F)F InChI=1/C11H9F5N4O3S/c12-8(13)4-23-7-3-1-2-6(11(14,15)16)9(7)24(21,22)20-10-17-5-18-19-10/h1-3,5,8H,4H2,(H2,17,18,19,20) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Italy Penoxsulam (Final Addendum to the DAR) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance penoxsulam 22Sep2009 2009 doi:10.2903/j.efsa.2009.343r
+Penoxsulam 219714-96-2 single chemical entity Component is a metabolite of the substance 2-(2,2-Difluoroethoxy)-N-(1H-1,2,4-triazol-3-yl)-6-(trifluoromethyl)benzenesulfonamide 2-(2,2-difluoroethoxy)-N-(1H-1,2,4-triazol-3-yl)-6-(trifluoromethyl)benzenesulfonamide Not in list C11H9F5N4O3S O=S(=O)(Nc1ncnn1)c2c(cccc2OCC(F)F)C(F)(F)F InChI=1/C11H9F5N4O3S/c12-8(13)4-23-7-3-1-2-6(11(14,15)16)9(7)24(21,22)20-10-17-5-18-19-10/h1-3,5,8H,4H2,(H2,17,18,19,20) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Rat (as animal) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Italy Penoxsulam (Final Addendum to the DAR) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance penoxsulam 22Sep2009 2009 doi:10.2903/j.efsa.2009.343r
+Penoxsulam 219714-96-2 single chemical entity Component is a metabolite of the substance 2-(2,2-Difluoroethoxy)-N-(1H-1,2,4-triazol-3-yl)-6-(trifluoromethyl)benzenesulfonamide 2-(2,2-difluoroethoxy)-N-(1H-1,2,4-triazol-3-yl)-6-(trifluoromethyl)benzenesulfonamide Not in list C11H9F5N4O3S O=S(=O)(Nc1ncnn1)c2c(cccc2OCC(F)F)C(F)(F)F InChI=1/C11H9F5N4O3S/c12-8(13)4-23-7-3-1-2-6(11(14,15)16)9(7)24(21,22)20-10-17-5-18-19-10/h1-3,5,8H,4H2,(H2,17,18,19,20) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Rat (as animal) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Italy Penoxsulam (Final Addendum to the DAR) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance penoxsulam 22Sep2009 2009 doi:10.2903/j.efsa.2009.343r
+Pyridate 259-686-7 55512-33-9 single chemical entity Component is identical to the substance Pyridate 259-686-7 55512-33-9 O-6-chloro-3-phenylpyridazin-4-yl S-octyl thiocarbonate Pyridate C19H23CIN2O2S CCCCCCCCSC(=O)OC1=CC(=NN=C1C2=CC=CC=C2)Cl InChI=1S/C19H23ClN2O2S/c1-2-3-4-5-6-10-13-25-19(23)24-16-14-17(20)21-22-18(16)15-11-8-7-9-12-15/h7-9,11-12,14H,2-6,10,13H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Austria - CoRMS: Latvia Pyridate (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate 08Aug2014 2014 doi:10.2903/j.efsa.2014.3801
+Pyridate 259-686-7 55512-33-9 single chemical entity Component is identical to the substance Pyridate 259-686-7 55512-33-9 O-6-chloro-3-phenylpyridazin-4-yl S-octyl thiocarbonate Pyridate C19H23CIN2O2S CCCCCCCCSC(=O)OC1=CC(=NN=C1C2=CC=CC=C2)Cl InChI=1S/C19H23ClN2O2S/c1-2-3-4-5-6-10-13-25-19(23)24-16-14-17(20)21-22-18(16)15-11-8-7-9-12-15/h7-9,11-12,14H,2-6,10,13H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Austria - CoRMS: Latvia Pyridate (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate 08Aug2014 2014 doi:10.2903/j.efsa.2014.3801
+Pyridate 259-686-7 55512-33-9 single chemical entity Component is identical to the substance Pyridate 259-686-7 55512-33-9 O-6-chloro-3-phenylpyridazin-4-yl S-octyl thiocarbonate Pyridate C19H23CIN2O2S CCCCCCCCSC(=O)OC1=CC(=NN=C1C2=CC=CC=C2)Cl InChI=1S/C19H23ClN2O2S/c1-2-3-4-5-6-10-13-25-19(23)24-16-14-17(20)21-22-18(16)15-11-8-7-9-12-15/h7-9,11-12,14H,2-6,10,13H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: Austria - CoRMS: Latvia Pyridate (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate 08Aug2014 2014 doi:10.2903/j.efsa.2014.3801
+Pyridate 259-686-7 55512-33-9 single chemical entity Component is identical to the substance Pyridate 259-686-7 55512-33-9 O-6-chloro-3-phenylpyridazin-4-yl S-octyl thiocarbonate Pyridate C19H23CIN2O2S CCCCCCCCSC(=O)OC1=CC(=NN=C1C2=CC=CC=C2)Cl InChI=1S/C19H23ClN2O2S/c1-2-3-4-5-6-10-13-25-19(23)24-16-14-17(20)21-22-18(16)15-11-8-7-9-12-15/h7-9,11-12,14H,2-6,10,13H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Austria - CoRMS: Latvia Pyridate (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate 08Aug2014 2014 doi:10.2903/j.efsa.2014.3801
+Pyridate 259-686-7 55512-33-9 single chemical entity Component is identical to the substance Pyridate 259-686-7 55512-33-9 O-6-chloro-3-phenylpyridazin-4-yl S-octyl thiocarbonate Pyridate C19H23CIN2O2S CCCCCCCCSC(=O)OC1=CC(=NN=C1C2=CC=CC=C2)Cl InChI=1S/C19H23ClN2O2S/c1-2-3-4-5-6-10-13-25-19(23)24-16-14-17(20)21-22-18(16)15-11-8-7-9-12-15/h7-9,11-12,14H,2-6,10,13H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: Austria - CoRMS: Latvia Pyridate (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate 08Aug2014 2014 doi:10.2903/j.efsa.2014.3801
+Pyridate 259-686-7 55512-33-9 single chemical entity Component is identical to the substance Pyridate 259-686-7 55512-33-9 O-6-chloro-3-phenylpyridazin-4-yl S-octyl thiocarbonate Pyridate C19H23CIN2O2S CCCCCCCCSC(=O)OC1=CC(=NN=C1C2=CC=CC=C2)Cl InChI=1S/C19H23ClN2O2S/c1-2-3-4-5-6-10-13-25-19(23)24-16-14-17(20)21-22-18(16)15-11-8-7-9-12-15/h7-9,11-12,14H,2-6,10,13H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Austria - CoRMS: Latvia Pyridate (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate 08Aug2014 2014 doi:10.2903/j.efsa.2014.3801
+Pyridate 259-686-7 55512-33-9 single chemical entity Component is identical to the substance Pyridate 259-686-7 55512-33-9 O-6-chloro-3-phenylpyridazin-4-yl S-octyl thiocarbonate Pyridate C19H23CIN2O2S CCCCCCCCSC(=O)OC1=CC(=NN=C1C2=CC=CC=C2)Cl InChI=1S/C19H23ClN2O2S/c1-2-3-4-5-6-10-13-25-19(23)24-16-14-17(20)21-22-18(16)15-11-8-7-9-12-15/h7-9,11-12,14H,2-6,10,13H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Austria - CoRMS: Latvia Pyridate (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate 08Aug2014 2014 doi:10.2903/j.efsa.2014.3801
+Pyridate 259-686-7 55512-33-9 single chemical entity Component is identical to the substance Pyridate 259-686-7 55512-33-9 O-6-chloro-3-phenylpyridazin-4-yl S-octyl thiocarbonate Pyridate C19H23CIN2O2S CCCCCCCCSC(=O)OC1=CC(=NN=C1C2=CC=CC=C2)Cl InChI=1S/C19H23ClN2O2S/c1-2-3-4-5-6-10-13-25-19(23)24-16-14-17(20)21-22-18(16)15-11-8-7-9-12-15/h7-9,11-12,14H,2-6,10,13H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Austria - CoRMS: Latvia Pyridate (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate 08Aug2014 2014 doi:10.2903/j.efsa.2014.3801
+Pyridate 259-686-7 55512-33-9 single chemical entity Component is identical to the substance Pyridate 259-686-7 55512-33-9 O-6-chloro-3-phenylpyridazin-4-yl S-octyl thiocarbonate Pyridate C19H23CIN2O2S CCCCCCCCSC(=O)OC1=CC(=NN=C1C2=CC=CC=C2)Cl InChI=1S/C19H23ClN2O2S/c1-2-3-4-5-6-10-13-25-19(23)24-16-14-17(20)21-22-18(16)15-11-8-7-9-12-15/h7-9,11-12,14H,2-6,10,13H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Austria - CoRMS: Latvia Pyridate (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate 08Aug2014 2014 doi:10.2903/j.efsa.2014.3801
+Pyridate 259-686-7 55512-33-9 single chemical entity Component is identical to the substance Pyridate 259-686-7 55512-33-9 O-6-chloro-3-phenylpyridazin-4-yl S-octyl thiocarbonate Pyridate C19H23CIN2O2S CCCCCCCCSC(=O)OC1=CC(=NN=C1C2=CC=CC=C2)Cl InChI=1S/C19H23ClN2O2S/c1-2-3-4-5-6-10-13-25-19(23)24-16-14-17(20)21-22-18(16)15-11-8-7-9-12-15/h7-9,11-12,14H,2-6,10,13H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Austria - CoRMS: Latvia Pyridate (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate 08Aug2014 2014 doi:10.2903/j.efsa.2014.3801
+Pyridate 259-686-7 55512-33-9 single chemical entity Component is identical to the substance Pyridate 259-686-7 55512-33-9 O-6-chloro-3-phenylpyridazin-4-yl S-octyl thiocarbonate Pyridate C19H23CIN2O2S CCCCCCCCSC(=O)OC1=CC(=NN=C1C2=CC=CC=C2)Cl InChI=1S/C19H23ClN2O2S/c1-2-3-4-5-6-10-13-25-19(23)24-16-14-17(20)21-22-18(16)15-11-8-7-9-12-15/h7-9,11-12,14H,2-6,10,13H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: Austria - CoRMS: Latvia Pyridate (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate 08Aug2014 2014 doi:10.2903/j.efsa.2014.3801
+Pyridate 259-686-7 55512-33-9 single chemical entity Component is identical to the substance Pyridate 259-686-7 55512-33-9 O-6-chloro-3-phenylpyridazin-4-yl S-octyl thiocarbonate Pyridate C19H23CIN2O2S CCCCCCCCSC(=O)OC1=CC(=NN=C1C2=CC=CC=C2)Cl InChI=1S/C19H23ClN2O2S/c1-2-3-4-5-6-10-13-25-19(23)24-16-14-17(20)21-22-18(16)15-11-8-7-9-12-15/h7-9,11-12,14H,2-6,10,13H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: Austria - CoRMS: Latvia Pyridate (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate 08Aug2014 2014 doi:10.2903/j.efsa.2014.3801
+Pyridate 259-686-7 55512-33-9 single chemical entity Component is identical to the substance Pyridate 259-686-7 55512-33-9 O-6-chloro-3-phenylpyridazin-4-yl S-octyl thiocarbonate Pyridate C19H23CIN2O2S CCCCCCCCSC(=O)OC1=CC(=NN=C1C2=CC=CC=C2)Cl InChI=1S/C19H23ClN2O2S/c1-2-3-4-5-6-10-13-25-19(23)24-16-14-17(20)21-22-18(16)15-11-8-7-9-12-15/h7-9,11-12,14H,2-6,10,13H2,1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported no data without Negative RMS: Austria - CoRMS: Latvia Pyridate (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate 08Aug2014 2014 doi:10.2903/j.efsa.2014.3801
+Pyridate 259-686-7 55512-33-9 single chemical entity Component is identical to the substance Pyridate 259-686-7 55512-33-9 O-6-chloro-3-phenylpyridazin-4-yl S-octyl thiocarbonate Pyridate C19H23CIN2O2S CCCCCCCCSC(=O)OC1=CC(=NN=C1C2=CC=CC=C2)Cl InChI=1S/C19H23ClN2O2S/c1-2-3-4-5-6-10-13-25-19(23)24-16-14-17(20)21-22-18(16)15-11-8-7-9-12-15/h7-9,11-12,14H,2-6,10,13H2,1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported no data with Negative RMS: Austria - CoRMS: Latvia Pyridate (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate 08Aug2014 2014 doi:10.2903/j.efsa.2014.3801
+Pyridate 259-686-7 55512-33-9 single chemical entity Component is identical to the substance Pyridate 259-686-7 55512-33-9 O-6-chloro-3-phenylpyridazin-4-yl S-octyl thiocarbonate Pyridate C19H23CIN2O2S CCCCCCCCSC(=O)OC1=CC(=NN=C1C2=CC=CC=C2)Cl InChI=1S/C19H23ClN2O2S/c1-2-3-4-5-6-10-13-25-19(23)24-16-14-17(20)21-22-18(16)15-11-8-7-9-12-15/h7-9,11-12,14H,2-6,10,13H2,1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported no data without Negative RMS: Austria - CoRMS: Latvia Pyridate (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate 08Aug2014 2014 doi:10.2903/j.efsa.2014.3801
+Pyridate 259-686-7 55512-33-9 single chemical entity Component is identical to the substance Pyridate 259-686-7 55512-33-9 O-6-chloro-3-phenylpyridazin-4-yl S-octyl thiocarbonate Pyridate C19H23CIN2O2S CCCCCCCCSC(=O)OC1=CC(=NN=C1C2=CC=CC=C2)Cl InChI=1S/C19H23ClN2O2S/c1-2-3-4-5-6-10-13-25-19(23)24-16-14-17(20)21-22-18(16)15-11-8-7-9-12-15/h7-9,11-12,14H,2-6,10,13H2,1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported no data with Negative RMS: Austria - CoRMS: Latvia Pyridate (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate 08Aug2014 2014 doi:10.2903/j.efsa.2014.3801
+Pyridate 259-686-7 55512-33-9 single chemical entity Component is identical to the substance Pyridate 259-686-7 55512-33-9 O-6-chloro-3-phenylpyridazin-4-yl S-octyl thiocarbonate Pyridate C19H23CIN2O2S CCCCCCCCSC(=O)OC1=CC(=NN=C1C2=CC=CC=C2)Cl InChI=1S/C19H23ClN2O2S/c1-2-3-4-5-6-10-13-25-19(23)24-16-14-17(20)21-22-18(16)15-11-8-7-9-12-15/h7-9,11-12,14H,2-6,10,13H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Austria - CoRMS: Latvia Pyridate (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate 08Aug2014 2014 doi:10.2903/j.efsa.2014.3801
+Pyridate 259-686-7 55512-33-9 single chemical entity Component is identical to the substance Pyridate 259-686-7 55512-33-9 O-6-chloro-3-phenylpyridazin-4-yl S-octyl thiocarbonate Pyridate C19H23CIN2O2S CCCCCCCCSC(=O)OC1=CC(=NN=C1C2=CC=CC=C2)Cl InChI=1S/C19H23ClN2O2S/c1-2-3-4-5-6-10-13-25-19(23)24-16-14-17(20)21-22-18(16)15-11-8-7-9-12-15/h7-9,11-12,14H,2-6,10,13H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Austria - CoRMS: Latvia Pyridate (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate 08Aug2014 2014 doi:10.2903/j.efsa.2014.3801
+Pyridate 259-686-7 55512-33-9 single chemical entity Component is identical to the substance Pyridate 259-686-7 55512-33-9 O-6-chloro-3-phenylpyridazin-4-yl S-octyl thiocarbonate Pyridate C19H23CIN2O2S CCCCCCCCSC(=O)OC1=CC(=NN=C1C2=CC=CC=C2)Cl InChI=1S/C19H23ClN2O2S/c1-2-3-4-5-6-10-13-25-19(23)24-16-14-17(20)21-22-18(16)15-11-8-7-9-12-15/h7-9,11-12,14H,2-6,10,13H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Austria - CoRMS: Latvia Pyridate (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate 08Aug2014 2014 doi:10.2903/j.efsa.2014.3801
+Pyridate 259-686-7 55512-33-9 single chemical entity Component is identical to the substance Pyridate 259-686-7 55512-33-9 O-6-chloro-3-phenylpyridazin-4-yl S-octyl thiocarbonate Pyridate C19H23CIN2O2S CCCCCCCCSC(=O)OC1=CC(=NN=C1C2=CC=CC=C2)Cl InChI=1S/C19H23ClN2O2S/c1-2-3-4-5-6-10-13-25-19(23)24-16-14-17(20)21-22-18(16)15-11-8-7-9-12-15/h7-9,11-12,14H,2-6,10,13H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Austria - CoRMS: Latvia Pyridate (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate 08Aug2014 2014 doi:10.2903/j.efsa.2014.3801
+Pyridate 259-686-7 55512-33-9 single chemical entity Component is identical to the substance Pyridate 259-686-7 55512-33-9 O-6-chloro-3-phenylpyridazin-4-yl S-octyl thiocarbonate Pyridate C19H23CIN2O2S CCCCCCCCSC(=O)OC1=CC(=NN=C1C2=CC=CC=C2)Cl InChI=1S/C19H23ClN2O2S/c1-2-3-4-5-6-10-13-25-19(23)24-16-14-17(20)21-22-18(16)15-11-8-7-9-12-15/h7-9,11-12,14H,2-6,10,13H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Austria - CoRMS: Latvia Pyridate (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate 08Aug2014 2014 doi:10.2903/j.efsa.2014.3801
+Pyridate 259-686-7 55512-33-9 single chemical entity Component is identical to the substance Pyridate 259-686-7 55512-33-9 O-6-chloro-3-phenylpyridazin-4-yl S-octyl thiocarbonate Pyridate C19H23CIN2O2S CCCCCCCCSC(=O)OC1=CC(=NN=C1C2=CC=CC=C2)Cl InChI=1S/C19H23ClN2O2S/c1-2-3-4-5-6-10-13-25-19(23)24-16-14-17(20)21-22-18(16)15-11-8-7-9-12-15/h7-9,11-12,14H,2-6,10,13H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Austria - CoRMS: Latvia Pyridate (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate 08Aug2014 2014 doi:10.2903/j.efsa.2014.3801
+Pyridate 259-686-7 55512-33-9 single chemical entity Component is identical to the substance Pyridate 259-686-7 55512-33-9 O-6-chloro-3-phenylpyridazin-4-yl S-octyl thiocarbonate Pyridate C19H23CIN2O2S CCCCCCCCSC(=O)OC1=CC(=NN=C1C2=CC=CC=C2)Cl InChI=1S/C19H23ClN2O2S/c1-2-3-4-5-6-10-13-25-19(23)24-16-14-17(20)21-22-18(16)15-11-8-7-9-12-15/h7-9,11-12,14H,2-6,10,13H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Austria - CoRMS: Latvia Pyridate (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate 08Aug2014 2014 doi:10.2903/j.efsa.2014.3801
+Pyridate 259-686-7 55512-33-9 single chemical entity Component is identical to the substance Pyridate 259-686-7 55512-33-9 O-6-chloro-3-phenylpyridazin-4-yl S-octyl thiocarbonate Pyridate C19H23CIN2O2S CCCCCCCCSC(=O)OC1=CC(=NN=C1C2=CC=CC=C2)Cl InChI=1S/C19H23ClN2O2S/c1-2-3-4-5-6-10-13-25-19(23)24-16-14-17(20)21-22-18(16)15-11-8-7-9-12-15/h7-9,11-12,14H,2-6,10,13H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Austria - CoRMS: Latvia Pyridate (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate 08Aug2014 2014 doi:10.2903/j.efsa.2014.3801
+Pyridate 259-686-7 55512-33-9 single chemical entity Component is identical to the substance Pyridate 259-686-7 55512-33-9 O-6-chloro-3-phenylpyridazin-4-yl S-octyl thiocarbonate Pyridate C19H23CIN2O2S CCCCCCCCSC(=O)OC1=CC(=NN=C1C2=CC=CC=C2)Cl InChI=1S/C19H23ClN2O2S/c1-2-3-4-5-6-10-13-25-19(23)24-16-14-17(20)21-22-18(16)15-11-8-7-9-12-15/h7-9,11-12,14H,2-6,10,13H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Austria - CoRMS: Latvia Pyridate (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate 08Aug2014 2014 doi:10.2903/j.efsa.2014.3801
+Pyridate 259-686-7 55512-33-9 single chemical entity Component is identical to the substance Pyridate 259-686-7 55512-33-9 O-6-chloro-3-phenylpyridazin-4-yl S-octyl thiocarbonate Pyridate C19H23CIN2O2S CCCCCCCCSC(=O)OC1=CC(=NN=C1C2=CC=CC=C2)Cl InChI=1S/C19H23ClN2O2S/c1-2-3-4-5-6-10-13-25-19(23)24-16-14-17(20)21-22-18(16)15-11-8-7-9-12-15/h7-9,11-12,14H,2-6,10,13H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Austria - CoRMS: Latvia Pyridate (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate 08Aug2014 2014 doi:10.2903/j.efsa.2014.3801
+Pyridate 259-686-7 55512-33-9 single chemical entity Component is identical to the substance Pyridate 259-686-7 55512-33-9 O-6-chloro-3-phenylpyridazin-4-yl S-octyl thiocarbonate Pyridate C19H23CIN2O2S CCCCCCCCSC(=O)OC1=CC(=NN=C1C2=CC=CC=C2)Cl InChI=1S/C19H23ClN2O2S/c1-2-3-4-5-6-10-13-25-19(23)24-16-14-17(20)21-22-18(16)15-11-8-7-9-12-15/h7-9,11-12,14H,2-6,10,13H2,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported no data without Negative RMS: Austria - CoRMS: Latvia Pyridate (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate 08Aug2014 2014 doi:10.2903/j.efsa.2014.3801
+Pyridate 259-686-7 55512-33-9 single chemical entity Component is identical to the substance Pyridate 259-686-7 55512-33-9 O-6-chloro-3-phenylpyridazin-4-yl S-octyl thiocarbonate Pyridate C19H23CIN2O2S CCCCCCCCSC(=O)OC1=CC(=NN=C1C2=CC=CC=C2)Cl InChI=1S/C19H23ClN2O2S/c1-2-3-4-5-6-10-13-25-19(23)24-16-14-17(20)21-22-18(16)15-11-8-7-9-12-15/h7-9,11-12,14H,2-6,10,13H2,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported no data with Negative RMS: Austria - CoRMS: Latvia Pyridate (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate 08Aug2014 2014 doi:10.2903/j.efsa.2014.3801
+Pyridate 259-686-7 55512-33-9 single chemical entity Component is identical to the substance Pyridate 259-686-7 55512-33-9 O-6-chloro-3-phenylpyridazin-4-yl S-octyl thiocarbonate Pyridate C19H23CIN2O2S CCCCCCCCSC(=O)OC1=CC(=NN=C1C2=CC=CC=C2)Cl InChI=1S/C19H23ClN2O2S/c1-2-3-4-5-6-10-13-25-19(23)24-16-14-17(20)21-22-18(16)15-11-8-7-9-12-15/h7-9,11-12,14H,2-6,10,13H2,1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported no data without Negative RMS: Austria - CoRMS: Latvia Pyridate (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate 08Aug2014 2014 doi:10.2903/j.efsa.2014.3801
+Pyridate 259-686-7 55512-33-9 single chemical entity Component is identical to the substance Pyridate 259-686-7 55512-33-9 O-6-chloro-3-phenylpyridazin-4-yl S-octyl thiocarbonate Pyridate C19H23CIN2O2S CCCCCCCCSC(=O)OC1=CC(=NN=C1C2=CC=CC=C2)Cl InChI=1S/C19H23ClN2O2S/c1-2-3-4-5-6-10-13-25-19(23)24-16-14-17(20)21-22-18(16)15-11-8-7-9-12-15/h7-9,11-12,14H,2-6,10,13H2,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Swiss No data Not reported no data not applicable Negative no evidence RMS: Austria - CoRMS: Latvia Pyridate (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate 08Aug2014 2014 doi:10.2903/j.efsa.2014.3801
+Pyridate 259-686-7 55512-33-9 single chemical entity Component is identical to the substance Pyridate 259-686-7 55512-33-9 O-6-chloro-3-phenylpyridazin-4-yl S-octyl thiocarbonate Pyridate C19H23CIN2O2S CCCCCCCCSC(=O)OC1=CC(=NN=C1C2=CC=CC=C2)Cl InChI=1S/C19H23ClN2O2S/c1-2-3-4-5-6-10-13-25-19(23)24-16-14-17(20)21-22-18(16)15-11-8-7-9-12-15/h7-9,11-12,14H,2-6,10,13H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mouse spot test in vivo Equivalent or similar to OECD Guideline 484 (Genetic Toxicology: Mouse Spot Test) Yes Acceptable House mouse (as animal) C57BL Male/Female oral: unspecified no data not applicable Negative RMS: Austria - CoRMS: Latvia Pyridate (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate 08Aug2014 2014 doi:10.2903/j.efsa.2014.3801
+Pyridate 259-686-7 55512-33-9 single chemical entity Component is identical to the substance Pyridate 259-686-7 55512-33-9 O-6-chloro-3-phenylpyridazin-4-yl S-octyl thiocarbonate Pyridate C19H23CIN2O2S CCCCCCCCSC(=O)OC1=CC(=NN=C1C2=CC=CC=C2)Cl InChI=1S/C19H23ClN2O2S/c1-2-3-4-5-6-10-13-25-19(23)24-16-14-17(20)21-22-18(16)15-11-8-7-9-12-15/h7-9,11-12,14H,2-6,10,13H2,1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo Equivalent or similar to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No data Acceptable Rat (as animal) Fischer344 No data oral: unspecified no data not applicable Negative RMS: Austria - CoRMS: Latvia Pyridate (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate 08Aug2014 2014 doi:10.2903/j.efsa.2014.3801
+Pyridate 259-686-7 55512-33-9 single chemical entity Component is a metabolite of the substance Pyridafol 254-752-1 40020-01-7 6-chloro-3-phenylpyridazin-4-ol CL 9673 (6-chloro-4-hydroxy-3-phenylpyridazin) C10H7ClN2O C1=CC=C(C=C1)C2=NN=C(C=C2O)Cl InChI=1S/C10H7ClN2O/c11-9-6-8(14)10(13-12-9)7-4-2-1-3-5-7/h1-6H,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: Austria - CoRMS: Latvia Pyridate (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate 08Aug2014 2014 doi:10.2903/j.efsa.2014.3801
+Pyridate 259-686-7 55512-33-9 single chemical entity Component is a metabolite of the substance Pyridafol 254-752-1 40020-01-7 6-chloro-3-phenylpyridazin-4-ol CL 9673 (6-chloro-4-hydroxy-3-phenylpyridazin) C10H7ClN2O C1=CC=C(C=C1)C2=NN=C(C=C2O)Cl InChI=1S/C10H7ClN2O/c11-9-6-8(14)10(13-12-9)7-4-2-1-3-5-7/h1-6H,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Austria - CoRMS: Latvia Pyridate (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate 08Aug2014 2014 doi:10.2903/j.efsa.2014.3801
+Pyridate 259-686-7 55512-33-9 single chemical entity Component is a metabolite of the substance Pyridafol 254-752-1 40020-01-7 6-chloro-3-phenylpyridazin-4-ol CL 9673 (6-chloro-4-hydroxy-3-phenylpyridazin) C10H7ClN2O C1=CC=C(C=C1)C2=NN=C(C=C2O)Cl InChI=1S/C10H7ClN2O/c11-9-6-8(14)10(13-12-9)7-4-2-1-3-5-7/h1-6H,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Austria - CoRMS: Latvia Pyridate (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate 08Aug2014 2014 doi:10.2903/j.efsa.2014.3801
+Pyridate 259-686-7 55512-33-9 single chemical entity Component is a metabolite of the substance Pyridafol 254-752-1 40020-01-7 6-chloro-3-phenylpyridazin-4-ol CL 9673 (6-chloro-4-hydroxy-3-phenylpyridazin) C10H7ClN2O C1=CC=C(C=C1)C2=NN=C(C=C2O)Cl InChI=1S/C10H7ClN2O/c11-9-6-8(14)10(13-12-9)7-4-2-1-3-5-7/h1-6H,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Austria - CoRMS: Latvia Pyridate (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate 08Aug2014 2014 doi:10.2903/j.efsa.2014.3801
+Pyridate 259-686-7 55512-33-9 single chemical entity Component is a metabolite of the substance Pyridafol 254-752-1 40020-01-7 6-chloro-3-phenylpyridazin-4-ol CL 9673 (6-chloro-4-hydroxy-3-phenylpyridazin) C10H7ClN2O C1=CC=C(C=C1)C2=NN=C(C=C2O)Cl InChI=1S/C10H7ClN2O/c11-9-6-8(14)10(13-12-9)7-4-2-1-3-5-7/h1-6H,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Austria - CoRMS: Latvia Pyridate (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate 08Aug2014 2014 doi:10.2903/j.efsa.2014.3801
+Pyridate 259-686-7 55512-33-9 single chemical entity Component is a metabolite of the substance Pyridafol 254-752-1 40020-01-7 6-chloro-3-phenylpyridazin-4-ol CL 9673 (6-chloro-4-hydroxy-3-phenylpyridazin) C10H7ClN2O C1=CC=C(C=C1)C2=NN=C(C=C2O)Cl InChI=1S/C10H7ClN2O/c11-9-6-8(14)10(13-12-9)7-4-2-1-3-5-7/h1-6H,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Austria - CoRMS: Latvia Pyridate (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate 08Aug2014 2014 doi:10.2903/j.efsa.2014.3801
+Pyridate 259-686-7 55512-33-9 single chemical entity Component is a metabolite of the substance Pyridafol 254-752-1 40020-01-7 6-chloro-3-phenylpyridazin-4-ol CL 9673 (6-chloro-4-hydroxy-3-phenylpyridazin) C10H7ClN2O C1=CC=C(C=C1)C2=NN=C(C=C2O)Cl InChI=1S/C10H7ClN2O/c11-9-6-8(14)10(13-12-9)7-4-2-1-3-5-7/h1-6H,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Austria - CoRMS: Latvia Pyridate (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate 08Aug2014 2014 doi:10.2903/j.efsa.2014.3801
+Pyridate 259-686-7 55512-33-9 single chemical entity Component is a metabolite of the substance Pyridafol 254-752-1 40020-01-7 6-chloro-3-phenylpyridazin-4-ol CL 9673 (6-chloro-4-hydroxy-3-phenylpyridazin) C10H7ClN2O C1=CC=C(C=C1)C2=NN=C(C=C2O)Cl InChI=1S/C10H7ClN2O/c11-9-6-8(14)10(13-12-9)7-4-2-1-3-5-7/h1-6H,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: Austria - CoRMS: Latvia Pyridate (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate 08Aug2014 2014 doi:10.2903/j.efsa.2014.3801
+Pyridate 259-686-7 55512-33-9 single chemical entity Component is a metabolite of the substance Pyridafol 254-752-1 40020-01-7 6-chloro-3-phenylpyridazin-4-ol CL 9673 (6-chloro-4-hydroxy-3-phenylpyridazin) C10H7ClN2O C1=CC=C(C=C1)C2=NN=C(C=C2O)Cl InChI=1S/C10H7ClN2O/c11-9-6-8(14)10(13-12-9)7-4-2-1-3-5-7/h1-6H,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Austria - CoRMS: Latvia Pyridate (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate 08Aug2014 2014 doi:10.2903/j.efsa.2014.3801
+Pyridate 259-686-7 55512-33-9 single chemical entity Component is a metabolite of the substance Pyridafol 254-752-1 40020-01-7 6-chloro-3-phenylpyridazin-4-ol CL 9673 (6-chloro-4-hydroxy-3-phenylpyridazin) C10H7ClN2O C1=CC=C(C=C1)C2=NN=C(C=C2O)Cl InChI=1S/C10H7ClN2O/c11-9-6-8(14)10(13-12-9)7-4-2-1-3-5-7/h1-6H,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Austria - CoRMS: Latvia Pyridate (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate 08Aug2014 2014 doi:10.2903/j.efsa.2014.3801
+Pyridate 259-686-7 55512-33-9 single chemical entity Component is a metabolite of the substance Pyridafol 254-752-1 40020-01-7 6-chloro-3-phenylpyridazin-4-ol CL 9673 (6-chloro-4-hydroxy-3-phenylpyridazin) C10H7ClN2O C1=CC=C(C=C1)C2=NN=C(C=C2O)Cl InChI=1S/C10H7ClN2O/c11-9-6-8(14)10(13-12-9)7-4-2-1-3-5-7/h1-6H,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: Austria - CoRMS: Latvia Pyridate (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate 08Aug2014 2014 doi:10.2903/j.efsa.2014.3801
+Pyridate 259-686-7 55512-33-9 single chemical entity Component is a metabolite of the substance Pyridafol 254-752-1 40020-01-7 6-chloro-3-phenylpyridazin-4-ol CL 9673 (6-chloro-4-hydroxy-3-phenylpyridazin) C10H7ClN2O C1=CC=C(C=C1)C2=NN=C(C=C2O)Cl InChI=1S/C10H7ClN2O/c11-9-6-8(14)10(13-12-9)7-4-2-1-3-5-7/h1-6H,(H,12,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: Austria - CoRMS: Latvia Pyridate (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate 08Aug2014 2014 doi:10.2903/j.efsa.2014.3801
+Pyridate 259-686-7 55512-33-9 single chemical entity Component is a metabolite of the substance 6-chloro-4-methoxy-3-phenylpyridazine 40020-02-8 6-chloro-4-methoxy-3-phenylpyridazine Not in list C11H9ClN2O COC1=CC(=NN=C1C2=CC=CC=C2)Cl InChI=1S/C11H9ClN2O/c1-15-9-7-10(12)13-14-11(9)8-5-3-2-4-6-8/h2-7H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Austria - CoRMS: Latvia Pyridate (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate 08Aug2014 2014 doi:10.2903/j.efsa.2014.3801
+Pyridate 259-686-7 55512-33-9 single chemical entity Component is a metabolite of the substance 6-chloro-4-methoxy-3-phenylpyridazine 40020-02-8 6-chloro-4-methoxy-3-phenylpyridazine Not in list C11H9ClN2O COC1=CC(=NN=C1C2=CC=CC=C2)Cl InChI=1S/C11H9ClN2O/c1-15-9-7-10(12)13-14-11(9)8-5-3-2-4-6-8/h2-7H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Austria - CoRMS: Latvia Pyridate (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate 08Aug2014 2014 doi:10.2903/j.efsa.2014.3801
+Pyridate 259-686-7 55512-33-9 single chemical entity Component is a metabolite of the substance 6-chloro-4-methoxy-3-phenylpyridazine 40020-02-8 6-chloro-4-methoxy-3-phenylpyridazine Not in list C11H9ClN2O COC1=CC(=NN=C1C2=CC=CC=C2)Cl InChI=1S/C11H9ClN2O/c1-15-9-7-10(12)13-14-11(9)8-5-3-2-4-6-8/h2-7H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Austria - CoRMS: Latvia Pyridate (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate 08Aug2014 2014 doi:10.2903/j.efsa.2014.3801
+Pyridate 259-686-7 55512-33-9 single chemical entity Component is a metabolite of the substance 6-chloro-4-methoxy-3-phenylpyridazine 40020-02-8 6-chloro-4-methoxy-3-phenylpyridazine Not in list C11H9ClN2O COC1=CC(=NN=C1C2=CC=CC=C2)Cl InChI=1S/C11H9ClN2O/c1-15-9-7-10(12)13-14-11(9)8-5-3-2-4-6-8/h2-7H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Austria - CoRMS: Latvia Pyridate (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate 08Aug2014 2014 doi:10.2903/j.efsa.2014.3801
+Pyridate 259-686-7 55512-33-9 single chemical entity Component is a metabolite of the substance 6-chloro-4-methoxy-3-phenylpyridazine 40020-02-8 6-chloro-4-methoxy-3-phenylpyridazine Not in list C11H9ClN2O COC1=CC(=NN=C1C2=CC=CC=C2)Cl InChI=1S/C11H9ClN2O/c1-15-9-7-10(12)13-14-11(9)8-5-3-2-4-6-8/h2-7H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Austria - CoRMS: Latvia Pyridate (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate 08Aug2014 2014 doi:10.2903/j.efsa.2014.3801
+Pyridate 259-686-7 55512-33-9 single chemical entity Component is a metabolite of the substance 6-chloro-4-methoxy-3-phenylpyridazine 40020-02-8 6-chloro-4-methoxy-3-phenylpyridazine Not in list C11H9ClN2O COC1=CC(=NN=C1C2=CC=CC=C2)Cl InChI=1S/C11H9ClN2O/c1-15-9-7-10(12)13-14-11(9)8-5-3-2-4-6-8/h2-7H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Austria - CoRMS: Latvia Pyridate (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate 08Aug2014 2014 doi:10.2903/j.efsa.2014.3801
+Pyridate 259-686-7 55512-33-9 single chemical entity Component is a metabolite of the substance 6-chloro-4-methoxy-3-phenylpyridazine 40020-02-8 6-chloro-4-methoxy-3-phenylpyridazine Not in list C11H9ClN2O COC1=CC(=NN=C1C2=CC=CC=C2)Cl InChI=1S/C11H9ClN2O/c1-15-9-7-10(12)13-14-11(9)8-5-3-2-4-6-8/h2-7H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Austria - CoRMS: Latvia Pyridate (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate 08Aug2014 2014 doi:10.2903/j.efsa.2014.3801
+Pyridate 259-686-7 55512-33-9 single chemical entity Component is a metabolite of the substance 6-chloro-4-methoxy-3-phenylpyridazine 40020-02-8 6-chloro-4-methoxy-3-phenylpyridazine Not in list C11H9ClN2O COC1=CC(=NN=C1C2=CC=CC=C2)Cl InChI=1S/C11H9ClN2O/c1-15-9-7-10(12)13-14-11(9)8-5-3-2-4-6-8/h2-7H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Austria - CoRMS: Latvia Pyridate (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate 08Aug2014 2014 doi:10.2903/j.efsa.2014.3801
+Pyridate 259-686-7 55512-33-9 single chemical entity Component is a metabolite of the substance 6-chloro-4-methoxy-3-phenylpyridazine 40020-02-8 6-chloro-4-methoxy-3-phenylpyridazine Not in list C11H9ClN2O COC1=CC(=NN=C1C2=CC=CC=C2)Cl InChI=1S/C11H9ClN2O/c1-15-9-7-10(12)13-14-11(9)8-5-3-2-4-6-8/h2-7H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Austria - CoRMS: Latvia Pyridate (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate 08Aug2014 2014 doi:10.2903/j.efsa.2014.3801
+Pyridate 259-686-7 55512-33-9 single chemical entity Component is a metabolite of the substance 6-chloro-4-methoxy-3-phenylpyridazine 40020-02-8 6-chloro-4-methoxy-3-phenylpyridazine Not in list C11H9ClN2O COC1=CC(=NN=C1C2=CC=CC=C2)Cl InChI=1S/C11H9ClN2O/c1-15-9-7-10(12)13-14-11(9)8-5-3-2-4-6-8/h2-7H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Austria - CoRMS: Latvia Pyridate (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate 08Aug2014 2014 doi:10.2903/j.efsa.2014.3801
+Prosulfuron 94125-34-5 single chemical entity Component is identical to the substance Prosulfuron 94125-34-5 1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea Prosulfuron C15H16F3N5O4S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is identical to the substance Prosulfuron 94125-34-5 1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea Prosulfuron C15H16F3N5O4S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is identical to the substance Prosulfuron 94125-34-5 1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea Prosulfuron C15H16F3N5O4S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is identical to the substance Prosulfuron 94125-34-5 1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea Prosulfuron C15H16F3N5O4S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is identical to the substance Prosulfuron 94125-34-5 1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea Prosulfuron C15H16F3N5O4S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is identical to the substance Prosulfuron 94125-34-5 1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea Prosulfuron C15H16F3N5O4S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is identical to the substance Prosulfuron 94125-34-5 1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea Prosulfuron C15H16F3N5O4S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is identical to the substance Prosulfuron 94125-34-5 1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea Prosulfuron C15H16F3N5O4S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is identical to the substance Prosulfuron 94125-34-5 1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea Prosulfuron C15H16F3N5O4S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is identical to the substance Prosulfuron 94125-34-5 1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea Prosulfuron C15H16F3N5O4S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is identical to the substance Prosulfuron 94125-34-5 1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea Prosulfuron C15H16F3N5O4S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is identical to the substance Prosulfuron 94125-34-5 1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea Prosulfuron C15H16F3N5O4S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is identical to the substance Prosulfuron 94125-34-5 1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea Prosulfuron C15H16F3N5O4S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is identical to the substance Prosulfuron 94125-34-5 1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea Prosulfuron C15H16F3N5O4S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is identical to the substance Prosulfuron 94125-34-5 1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea Prosulfuron C15H16F3N5O4S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is identical to the substance Prosulfuron 94125-34-5 1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea Prosulfuron C15H16F3N5O4S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is identical to the substance Prosulfuron 94125-34-5 1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea Prosulfuron C15H16F3N5O4S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is identical to the substance Prosulfuron 94125-34-5 1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea Prosulfuron C15H16F3N5O4S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is identical to the substance Prosulfuron 94125-34-5 1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea Prosulfuron C15H16F3N5O4S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is identical to the substance Prosulfuron 94125-34-5 1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea Prosulfuron C15H16F3N5O4S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is identical to the substance Prosulfuron 94125-34-5 1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea Prosulfuron C15H16F3N5O4S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is identical to the substance Prosulfuron 94125-34-5 1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea Prosulfuron C15H16F3N5O4S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is identical to the substance Prosulfuron 94125-34-5 1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea Prosulfuron C15H16F3N5O4S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is identical to the substance Prosulfuron 94125-34-5 1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea Prosulfuron C15H16F3N5O4S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is identical to the substance Prosulfuron 94125-34-5 1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea Prosulfuron C15H16F3N5O4S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is identical to the substance Prosulfuron 94125-34-5 1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea Prosulfuron C15H16F3N5O4S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is identical to the substance Prosulfuron 94125-34-5 1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea Prosulfuron C15H16F3N5O4S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is identical to the substance Prosulfuron 94125-34-5 1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea Prosulfuron C15H16F3N5O4S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is identical to the substance Prosulfuron 94125-34-5 1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea Prosulfuron C15H16F3N5O4S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is identical to the substance Prosulfuron 94125-34-5 1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea Prosulfuron C15H16F3N5O4S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is identical to the substance Prosulfuron 94125-34-5 1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea Prosulfuron C15H16F3N5O4S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is identical to the substance Prosulfuron 94125-34-5 1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea Prosulfuron C15H16F3N5O4S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is identical to the substance Prosulfuron 94125-34-5 1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea Prosulfuron C15H16F3N5O4S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is identical to the substance Prosulfuron 94125-34-5 1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea Prosulfuron C15H16F3N5O4S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is identical to the substance Prosulfuron 94125-34-5 1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea Prosulfuron C15H16F3N5O4S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data without Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is identical to the substance Prosulfuron 94125-34-5 1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea Prosulfuron C15H16F3N5O4S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data with Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is identical to the substance Prosulfuron 94125-34-5 1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea Prosulfuron C15H16F3N5O4S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported no data without Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is identical to the substance Prosulfuron 94125-34-5 1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea Prosulfuron C15H16F3N5O4S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported no data with Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is identical to the substance Prosulfuron 94125-34-5 1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea Prosulfuron C15H16F3N5O4S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported no data without Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is identical to the substance Prosulfuron 94125-34-5 1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea Prosulfuron C15H16F3N5O4S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Not reported No data Not reported no data not applicable Negative no evidence RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is a metabolite of the substance N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide Not in list C11H13F3N4O3S O=S(=O)(NC(=O)NC(=N)N)c1ccccc1CCC(F)(F)F InChI=1S/C11H13F3N4O3S/c12-11(13,14)6-5-7-3-1-2-4-8(7)22(20,21)18-10(19)17-9(15)16/h1-4H,5-6H2,(H5,15,16,17,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is a metabolite of the substance N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide Not in list C11H13F3N4O3S O=S(=O)(NC(=O)NC(=N)N)c1ccccc1CCC(F)(F)F InChI=1S/C11H13F3N4O3S/c12-11(13,14)6-5-7-3-1-2-4-8(7)22(20,21)18-10(19)17-9(15)16/h1-4H,5-6H2,(H5,15,16,17,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is a metabolite of the substance N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide Not in list C11H13F3N4O3S O=S(=O)(NC(=O)NC(=N)N)c1ccccc1CCC(F)(F)F InChI=1S/C11H13F3N4O3S/c12-11(13,14)6-5-7-3-1-2-4-8(7)22(20,21)18-10(19)17-9(15)16/h1-4H,5-6H2,(H5,15,16,17,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is a metabolite of the substance N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide Not in list C11H13F3N4O3S O=S(=O)(NC(=O)NC(=N)N)c1ccccc1CCC(F)(F)F InChI=1S/C11H13F3N4O3S/c12-11(13,14)6-5-7-3-1-2-4-8(7)22(20,21)18-10(19)17-9(15)16/h1-4H,5-6H2,(H5,15,16,17,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is a metabolite of the substance N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide Not in list C11H13F3N4O3S O=S(=O)(NC(=O)NC(=N)N)c1ccccc1CCC(F)(F)F InChI=1S/C11H13F3N4O3S/c12-11(13,14)6-5-7-3-1-2-4-8(7)22(20,21)18-10(19)17-9(15)16/h1-4H,5-6H2,(H5,15,16,17,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is a metabolite of the substance N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide Not in list C11H13F3N4O3S O=S(=O)(NC(=O)NC(=N)N)c1ccccc1CCC(F)(F)F InChI=1S/C11H13F3N4O3S/c12-11(13,14)6-5-7-3-1-2-4-8(7)22(20,21)18-10(19)17-9(15)16/h1-4H,5-6H2,(H5,15,16,17,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is a metabolite of the substance N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide Not in list C11H13F3N4O3S O=S(=O)(NC(=O)NC(=N)N)c1ccccc1CCC(F)(F)F InChI=1S/C11H13F3N4O3S/c12-11(13,14)6-5-7-3-1-2-4-8(7)22(20,21)18-10(19)17-9(15)16/h1-4H,5-6H2,(H5,15,16,17,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is a metabolite of the substance N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide Not in list C11H13F3N4O3S O=S(=O)(NC(=O)NC(=N)N)c1ccccc1CCC(F)(F)F InChI=1S/C11H13F3N4O3S/c12-11(13,14)6-5-7-3-1-2-4-8(7)22(20,21)18-10(19)17-9(15)16/h1-4H,5-6H2,(H5,15,16,17,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is a metabolite of the substance N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide Not in list C11H13F3N4O3S O=S(=O)(NC(=O)NC(=N)N)c1ccccc1CCC(F)(F)F InChI=1S/C11H13F3N4O3S/c12-11(13,14)6-5-7-3-1-2-4-8(7)22(20,21)18-10(19)17-9(15)16/h1-4H,5-6H2,(H5,15,16,17,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is a metabolite of the substance N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide Not in list C11H13F3N4O3S O=S(=O)(NC(=O)NC(=N)N)c1ccccc1CCC(F)(F)F InChI=1S/C11H13F3N4O3S/c12-11(13,14)6-5-7-3-1-2-4-8(7)22(20,21)18-10(19)17-9(15)16/h1-4H,5-6H2,(H5,15,16,17,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is a metabolite of the substance N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide Not in list C11H13F3N4O3S O=S(=O)(NC(=O)NC(=N)N)c1ccccc1CCC(F)(F)F InChI=1S/C11H13F3N4O3S/c12-11(13,14)6-5-7-3-1-2-4-8(7)22(20,21)18-10(19)17-9(15)16/h1-4H,5-6H2,(H5,15,16,17,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is a metabolite of the substance N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide Not in list C11H13F3N4O3S O=S(=O)(NC(=O)NC(=N)N)c1ccccc1CCC(F)(F)F InChI=1S/C11H13F3N4O3S/c12-11(13,14)6-5-7-3-1-2-4-8(7)22(20,21)18-10(19)17-9(15)16/h1-4H,5-6H2,(H5,15,16,17,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is a metabolite of the substance N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide Not in list C11H13F3N4O3S O=S(=O)(NC(=O)NC(=N)N)c1ccccc1CCC(F)(F)F InChI=1S/C11H13F3N4O3S/c12-11(13,14)6-5-7-3-1-2-4-8(7)22(20,21)18-10(19)17-9(15)16/h1-4H,5-6H2,(H5,15,16,17,18,19) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative large colonies RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is a metabolite of the substance N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide Not in list C11H13F3N4O3S O=S(=O)(NC(=O)NC(=N)N)c1ccccc1CCC(F)(F)F InChI=1S/C11H13F3N4O3S/c12-11(13,14)6-5-7-3-1-2-4-8(7)22(20,21)18-10(19)17-9(15)16/h1-4H,5-6H2,(H5,15,16,17,18,19) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative small colonies RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is a metabolite of the substance N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide Not in list C11H13F3N4O3S O=S(=O)(NC(=O)NC(=N)N)c1ccccc1CCC(F)(F)F InChI=1S/C11H13F3N4O3S/c12-11(13,14)6-5-7-3-1-2-4-8(7)22(20,21)18-10(19)17-9(15)16/h1-4H,5-6H2,(H5,15,16,17,18,19) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative small colonies RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is a metabolite of the substance N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide Not in list C11H13F3N4O3S O=S(=O)(NC(=O)NC(=N)N)c1ccccc1CCC(F)(F)F InChI=1S/C11H13F3N4O3S/c12-11(13,14)6-5-7-3-1-2-4-8(7)22(20,21)18-10(19)17-9(15)16/h1-4H,5-6H2,(H5,15,16,17,18,19) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative large colonies RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is a metabolite of the substance N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide Not in list C11H13F3N4O3S O=S(=O)(NC(=O)NC(=N)N)c1ccccc1CCC(F)(F)F InChI=1S/C11H13F3N4O3S/c12-11(13,14)6-5-7-3-1-2-4-8(7)22(20,21)18-10(19)17-9(15)16/h1-4H,5-6H2,(H5,15,16,17,18,19) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is a metabolite of the substance N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide Not in list C11H13F3N4O3S O=S(=O)(NC(=O)NC(=N)N)c1ccccc1CCC(F)(F)F InChI=1S/C11H13F3N4O3S/c12-11(13,14)6-5-7-3-1-2-4-8(7)22(20,21)18-10(19)17-9(15)16/h1-4H,5-6H2,(H5,15,16,17,18,19) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is a metabolite of the substance 2-(3,3,3-trifluoropropyl)benzenesulfonamide 2-(3,3,3-trifluoropropyl)benzenesulfonamide Not in list C9H10F3NO2S C1=CC=C(C(=C1)CCC(F)(F)F)S(=O)(=O)N InChI=1S/C9H10F3NO2S/c10-9(11,12)6-5-7-3-1-2-4-8(7)16(13,14)15/h1-4H,5-6H2,(H2,13,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is a metabolite of the substance 2-(3,3,3-trifluoropropyl)benzenesulfonamide 2-(3,3,3-trifluoropropyl)benzenesulfonamide Not in list C9H10F3NO2S C1=CC=C(C(=C1)CCC(F)(F)F)S(=O)(=O)N InChI=1S/C9H10F3NO2S/c10-9(11,12)6-5-7-3-1-2-4-8(7)16(13,14)15/h1-4H,5-6H2,(H2,13,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is a metabolite of the substance 2-(3,3,3-trifluoropropyl)benzenesulfonamide 2-(3,3,3-trifluoropropyl)benzenesulfonamide Not in list C9H10F3NO2S C1=CC=C(C(=C1)CCC(F)(F)F)S(=O)(=O)N InChI=1S/C9H10F3NO2S/c10-9(11,12)6-5-7-3-1-2-4-8(7)16(13,14)15/h1-4H,5-6H2,(H2,13,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is a metabolite of the substance 2-(3,3,3-trifluoropropyl)benzenesulfonamide 2-(3,3,3-trifluoropropyl)benzenesulfonamide Not in list C9H10F3NO2S C1=CC=C(C(=C1)CCC(F)(F)F)S(=O)(=O)N InChI=1S/C9H10F3NO2S/c10-9(11,12)6-5-7-3-1-2-4-8(7)16(13,14)15/h1-4H,5-6H2,(H2,13,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is a metabolite of the substance 2-(3,3,3-trifluoropropyl)benzenesulfonamide 2-(3,3,3-trifluoropropyl)benzenesulfonamide Not in list C9H10F3NO2S C1=CC=C(C(=C1)CCC(F)(F)F)S(=O)(=O)N InChI=1S/C9H10F3NO2S/c10-9(11,12)6-5-7-3-1-2-4-8(7)16(13,14)15/h1-4H,5-6H2,(H2,13,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is a metabolite of the substance 2-(3,3,3-trifluoropropyl)benzenesulfonamide 2-(3,3,3-trifluoropropyl)benzenesulfonamide Not in list C9H10F3NO2S C1=CC=C(C(=C1)CCC(F)(F)F)S(=O)(=O)N InChI=1S/C9H10F3NO2S/c10-9(11,12)6-5-7-3-1-2-4-8(7)16(13,14)15/h1-4H,5-6H2,(H2,13,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is a metabolite of the substance 2-(3,3,3-trifluoropropyl)benzenesulfonamide 2-(3,3,3-trifluoropropyl)benzenesulfonamide Not in list C9H10F3NO2S C1=CC=C(C(=C1)CCC(F)(F)F)S(=O)(=O)N InChI=1S/C9H10F3NO2S/c10-9(11,12)6-5-7-3-1-2-4-8(7)16(13,14)15/h1-4H,5-6H2,(H2,13,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is a metabolite of the substance 2-(3,3,3-trifluoropropyl)benzenesulfonamide 2-(3,3,3-trifluoropropyl)benzenesulfonamide Not in list C9H10F3NO2S C1=CC=C(C(=C1)CCC(F)(F)F)S(=O)(=O)N InChI=1S/C9H10F3NO2S/c10-9(11,12)6-5-7-3-1-2-4-8(7)16(13,14)15/h1-4H,5-6H2,(H2,13,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is a metabolite of the substance 2-(3,3,3-trifluoropropyl)benzenesulfonamide 2-(3,3,3-trifluoropropyl)benzenesulfonamide Not in list C9H10F3NO2S C1=CC=C(C(=C1)CCC(F)(F)F)S(=O)(=O)N InChI=1S/C9H10F3NO2S/c10-9(11,12)6-5-7-3-1-2-4-8(7)16(13,14)15/h1-4H,5-6H2,(H2,13,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is a metabolite of the substance 2-(3,3,3-trifluoropropyl)benzenesulfonamide 2-(3,3,3-trifluoropropyl)benzenesulfonamide Not in list C9H10F3NO2S C1=CC=C(C(=C1)CCC(F)(F)F)S(=O)(=O)N InChI=1S/C9H10F3NO2S/c10-9(11,12)6-5-7-3-1-2-4-8(7)16(13,14)15/h1-4H,5-6H2,(H2,13,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is a metabolite of the substance 2-(3,3,3-trifluoropropyl)benzenesulfonamide 2-(3,3,3-trifluoropropyl)benzenesulfonamide Not in list C9H10F3NO2S C1=CC=C(C(=C1)CCC(F)(F)F)S(=O)(=O)N InChI=1S/C9H10F3NO2S/c10-9(11,12)6-5-7-3-1-2-4-8(7)16(13,14)15/h1-4H,5-6H2,(H2,13,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative small colonies RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is a metabolite of the substance 2-(3,3,3-trifluoropropyl)benzenesulfonamide 2-(3,3,3-trifluoropropyl)benzenesulfonamide Not in list C9H10F3NO2S C1=CC=C(C(=C1)CCC(F)(F)F)S(=O)(=O)N InChI=1S/C9H10F3NO2S/c10-9(11,12)6-5-7-3-1-2-4-8(7)16(13,14)15/h1-4H,5-6H2,(H2,13,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Positive small colonies RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is a metabolite of the substance 2-(3,3,3-trifluoropropyl)benzenesulfonamide 2-(3,3,3-trifluoropropyl)benzenesulfonamide Not in list C9H10F3NO2S C1=CC=C(C(=C1)CCC(F)(F)F)S(=O)(=O)N InChI=1S/C9H10F3NO2S/c10-9(11,12)6-5-7-3-1-2-4-8(7)16(13,14)15/h1-4H,5-6H2,(H2,13,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative large colonies RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is a metabolite of the substance 2-(3,3,3-trifluoropropyl)benzenesulfonamide 2-(3,3,3-trifluoropropyl)benzenesulfonamide Not in list C9H10F3NO2S C1=CC=C(C(=C1)CCC(F)(F)F)S(=O)(=O)N InChI=1S/C9H10F3NO2S/c10-9(11,12)6-5-7-3-1-2-4-8(7)16(13,14)15/h1-4H,5-6H2,(H2,13,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative large colonies RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is a metabolite of the substance 2-(3,3,3-trifluoropropyl)benzenesulfonamide 2-(3,3,3-trifluoropropyl)benzenesulfonamide Not in list C9H10F3NO2S C1=CC=C(C(=C1)CCC(F)(F)F)S(=O)(=O)N InChI=1S/C9H10F3NO2S/c10-9(11,12)6-5-7-3-1-2-4-8(7)16(13,14)15/h1-4H,5-6H2,(H2,13,14,15) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Positive RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is a metabolite of the substance 2-(3,3,3-trifluoropropyl)benzenesulfonamide 2-(3,3,3-trifluoropropyl)benzenesulfonamide Not in list C9H10F3NO2S C1=CC=C(C(=C1)CCC(F)(F)F)S(=O)(=O)N InChI=1S/C9H10F3NO2S/c10-9(11,12)6-5-7-3-1-2-4-8(7)16(13,14)15/h1-4H,5-6H2,(H2,13,14,15) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is a metabolite of the substance 2-(3,3,3-trifluoropropyl)benzenesulfonamide 2-(3,3,3-trifluoropropyl)benzenesulfonamide Not in list C9H10F3NO2S C1=CC=C(C(=C1)CCC(F)(F)F)S(=O)(=O)N InChI=1S/C9H10F3NO2S/c10-9(11,12)6-5-7-3-1-2-4-8(7)16(13,14)15/h1-4H,5-6H2,(H2,13,14,15) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Alpk:APf SD Rat 10 Male oral: unspecified 16.0000000000 h yes, concurrent vehicle not applicable Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is a metabolite of the substance 2-(3,3,3-trifluoropropyl)benzenesulfonamide 2-(3,3,3-trifluoropropyl)benzenesulfonamide Not in list C9H10F3NO2S C1=CC=C(C(=C1)CCC(F)(F)F)S(=O)(=O)N InChI=1S/C9H10F3NO2S/c10-9(11,12)6-5-7-3-1-2-4-8(7)16(13,14)15/h1-4H,5-6H2,(H2,13,14,15) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Alpk:APf SD Rat 10 Male oral: unspecified 2.0000000000 h yes, concurrent vehicle not applicable Negative RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is a metabolite of the substance 2-(3,3,3-trifluoropropyl)benzenesulfonamide 2-(3,3,3-trifluoropropyl)benzenesulfonamide Not in list C9H10F3NO2S C1=CC=C(C(=C1)CCC(F)(F)F)S(=O)(=O)N InChI=1S/C9H10F3NO2S/c10-9(11,12)6-5-7-3-1-2-4-8(7)16(13,14)15/h1-4H,5-6H2,(H2,13,14,15) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 5 Male oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Prosulfuron 94125-34-5 single chemical entity Component is a metabolite of the substance 2-(3,3,3-trifluoropropyl)benzenesulfonamide 2-(3,3,3-trifluoropropyl)benzenesulfonamide Not in list C9H10F3NO2S C1=CC=C(C(=C1)CCC(F)(F)F)S(=O)(=O)N InChI=1S/C9H10F3NO2S/c10-9(11,12)6-5-7-3-1-2-4-8(7)16(13,14)15/h1-4H,5-6H2,(H2,13,14,15) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 5 Male oral: unspecified 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: France - CoRMS: Slovakia Prosulfuron 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron 02Sep2014 2014 doi:10.2903/j.efsa.2014.3815
+Pyridalyl 179101-81-6 single chemical entity Component is identical to the substance Pyridalyl 179101-81-6 2,6-dichloro-4-(3,3-dichloroallyloxy)phenyl 3-[5-(trifluoromethyl)-2-pyridyloxy]propyl ether Pyridalyl C18H14Cl4F3NO3 C1=CC(=NC(=C1)OCCCOC2=C(C=C(C=C2Cl)OCC=C(Cl)Cl)Cl)C(F)(F)F InChI=1S/C18H14Cl4F3NO3/c19-12-9-11(27-8-5-15(21)22)10-13(20)17(12)29-7-2-6-28-16-4-1-3-14(26-16)18(23,24)25/h1,3-5,9-10H,2,6-8H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: The Netherlands Pyridalyl (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3240
+Pyridalyl 179101-81-6 single chemical entity Component is identical to the substance Pyridalyl 179101-81-6 2,6-dichloro-4-(3,3-dichloroallyloxy)phenyl 3-[5-(trifluoromethyl)-2-pyridyloxy]propyl ether Pyridalyl C18H14Cl4F3NO3 C1=CC(=NC(=C1)OCCCOC2=C(C=C(C=C2Cl)OCC=C(Cl)Cl)Cl)C(F)(F)F InChI=1S/C18H14Cl4F3NO3/c19-12-9-11(27-8-5-15(21)22)10-13(20)17(12)29-7-2-6-28-16-4-1-3-14(26-16)18(23,24)25/h1,3-5,9-10H,2,6-8H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: The Netherlands Pyridalyl (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3240
+Pyridalyl 179101-81-6 single chemical entity Component is identical to the substance Pyridalyl 179101-81-6 2,6-dichloro-4-(3,3-dichloroallyloxy)phenyl 3-[5-(trifluoromethyl)-2-pyridyloxy]propyl ether Pyridalyl C18H14Cl4F3NO3 C1=CC(=NC(=C1)OCCCOC2=C(C=C(C=C2Cl)OCC=C(Cl)Cl)Cl)C(F)(F)F InChI=1S/C18H14Cl4F3NO3/c19-12-9-11(27-8-5-15(21)22)10-13(20)17(12)29-7-2-6-28-16-4-1-3-14(26-16)18(23,24)25/h1,3-5,9-10H,2,6-8H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: The Netherlands Pyridalyl (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3240
+Pyridalyl 179101-81-6 single chemical entity Component is identical to the substance Pyridalyl 179101-81-6 2,6-dichloro-4-(3,3-dichloroallyloxy)phenyl 3-[5-(trifluoromethyl)-2-pyridyloxy]propyl ether Pyridalyl C18H14Cl4F3NO3 C1=CC(=NC(=C1)OCCCOC2=C(C=C(C=C2Cl)OCC=C(Cl)Cl)Cl)C(F)(F)F InChI=1S/C18H14Cl4F3NO3/c19-12-9-11(27-8-5-15(21)22)10-13(20)17(12)29-7-2-6-28-16-4-1-3-14(26-16)18(23,24)25/h1,3-5,9-10H,2,6-8H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: The Netherlands Pyridalyl (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3240
+Pyridalyl 179101-81-6 single chemical entity Component is identical to the substance Pyridalyl 179101-81-6 2,6-dichloro-4-(3,3-dichloroallyloxy)phenyl 3-[5-(trifluoromethyl)-2-pyridyloxy]propyl ether Pyridalyl C18H14Cl4F3NO3 C1=CC(=NC(=C1)OCCCOC2=C(C=C(C=C2Cl)OCC=C(Cl)Cl)Cl)C(F)(F)F InChI=1S/C18H14Cl4F3NO3/c19-12-9-11(27-8-5-15(21)22)10-13(20)17(12)29-7-2-6-28-16-4-1-3-14(26-16)18(23,24)25/h1,3-5,9-10H,2,6-8H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: The Netherlands Pyridalyl (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3240
+Pyridalyl 179101-81-6 single chemical entity Component is identical to the substance Pyridalyl 179101-81-6 2,6-dichloro-4-(3,3-dichloroallyloxy)phenyl 3-[5-(trifluoromethyl)-2-pyridyloxy]propyl ether Pyridalyl C18H14Cl4F3NO3 C1=CC(=NC(=C1)OCCCOC2=C(C=C(C=C2Cl)OCC=C(Cl)Cl)Cl)C(F)(F)F InChI=1S/C18H14Cl4F3NO3/c19-12-9-11(27-8-5-15(21)22)10-13(20)17(12)29-7-2-6-28-16-4-1-3-14(26-16)18(23,24)25/h1,3-5,9-10H,2,6-8H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: The Netherlands Pyridalyl (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3240
+Pyridalyl 179101-81-6 single chemical entity Component is identical to the substance Pyridalyl 179101-81-6 2,6-dichloro-4-(3,3-dichloroallyloxy)phenyl 3-[5-(trifluoromethyl)-2-pyridyloxy]propyl ether Pyridalyl C18H14Cl4F3NO3 C1=CC(=NC(=C1)OCCCOC2=C(C=C(C=C2Cl)OCC=C(Cl)Cl)Cl)C(F)(F)F InChI=1S/C18H14Cl4F3NO3/c19-12-9-11(27-8-5-15(21)22)10-13(20)17(12)29-7-2-6-28-16-4-1-3-14(26-16)18(23,24)25/h1,3-5,9-10H,2,6-8H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: The Netherlands Pyridalyl (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3240
+Pyridalyl 179101-81-6 single chemical entity Component is identical to the substance Pyridalyl 179101-81-6 2,6-dichloro-4-(3,3-dichloroallyloxy)phenyl 3-[5-(trifluoromethyl)-2-pyridyloxy]propyl ether Pyridalyl C18H14Cl4F3NO3 C1=CC(=NC(=C1)OCCCOC2=C(C=C(C=C2Cl)OCC=C(Cl)Cl)Cl)C(F)(F)F InChI=1S/C18H14Cl4F3NO3/c19-12-9-11(27-8-5-15(21)22)10-13(20)17(12)29-7-2-6-28-16-4-1-3-14(26-16)18(23,24)25/h1,3-5,9-10H,2,6-8H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: The Netherlands Pyridalyl (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3240
+Pyridalyl 179101-81-6 single chemical entity Component is identical to the substance Pyridalyl 179101-81-6 2,6-dichloro-4-(3,3-dichloroallyloxy)phenyl 3-[5-(trifluoromethyl)-2-pyridyloxy]propyl ether Pyridalyl C18H14Cl4F3NO3 C1=CC(=NC(=C1)OCCCOC2=C(C=C(C=C2Cl)OCC=C(Cl)Cl)Cl)C(F)(F)F InChI=1S/C18H14Cl4F3NO3/c19-12-9-11(27-8-5-15(21)22)10-13(20)17(12)29-7-2-6-28-16-4-1-3-14(26-16)18(23,24)25/h1,3-5,9-10H,2,6-8H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: The Netherlands Pyridalyl (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3240
+Pyridalyl 179101-81-6 single chemical entity Component is identical to the substance Pyridalyl 179101-81-6 2,6-dichloro-4-(3,3-dichloroallyloxy)phenyl 3-[5-(trifluoromethyl)-2-pyridyloxy]propyl ether Pyridalyl C18H14Cl4F3NO3 C1=CC(=NC(=C1)OCCCOC2=C(C=C(C=C2Cl)OCC=C(Cl)Cl)Cl)C(F)(F)F InChI=1S/C18H14Cl4F3NO3/c19-12-9-11(27-8-5-15(21)22)10-13(20)17(12)29-7-2-6-28-16-4-1-3-14(26-16)18(23,24)25/h1,3-5,9-10H,2,6-8H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: The Netherlands Pyridalyl (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3240
+Pyridalyl 179101-81-6 single chemical entity Component is identical to the substance Pyridalyl 179101-81-6 2,6-dichloro-4-(3,3-dichloroallyloxy)phenyl 3-[5-(trifluoromethyl)-2-pyridyloxy]propyl ether Pyridalyl C18H14Cl4F3NO3 C1=CC(=NC(=C1)OCCCOC2=C(C=C(C=C2Cl)OCC=C(Cl)Cl)Cl)C(F)(F)F InChI=1S/C18H14Cl4F3NO3/c19-12-9-11(27-8-5-15(21)22)10-13(20)17(12)29-7-2-6-28-16-4-1-3-14(26-16)18(23,24)25/h1,3-5,9-10H,2,6-8H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data with Negative no information RMS: The Netherlands Pyridalyl (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3240
+Pyridalyl 179101-81-6 single chemical entity Component is identical to the substance Pyridalyl 179101-81-6 2,6-dichloro-4-(3,3-dichloroallyloxy)phenyl 3-[5-(trifluoromethyl)-2-pyridyloxy]propyl ether Pyridalyl C18H14Cl4F3NO3 C1=CC(=NC(=C1)OCCCOC2=C(C=C(C=C2Cl)OCC=C(Cl)Cl)Cl)C(F)(F)F InChI=1S/C18H14Cl4F3NO3/c19-12-9-11(27-8-5-15(21)22)10-13(20)17(12)29-7-2-6-28-16-4-1-3-14(26-16)18(23,24)25/h1,3-5,9-10H,2,6-8H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data without Negative no information RMS: The Netherlands Pyridalyl (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3240
+Pyridalyl 179101-81-6 single chemical entity Component is identical to the substance Pyridalyl 179101-81-6 2,6-dichloro-4-(3,3-dichloroallyloxy)phenyl 3-[5-(trifluoromethyl)-2-pyridyloxy]propyl ether Pyridalyl C18H14Cl4F3NO3 C1=CC(=NC(=C1)OCCCOC2=C(C=C(C=C2Cl)OCC=C(Cl)Cl)Cl)C(F)(F)F InChI=1S/C18H14Cl4F3NO3/c19-12-9-11(27-8-5-15(21)22)10-13(20)17(12)29-7-2-6-28-16-4-1-3-14(26-16)18(23,24)25/h1,3-5,9-10H,2,6-8H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported no data without Negative RMS: The Netherlands Pyridalyl (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3240
+Pyridalyl 179101-81-6 single chemical entity Component is identical to the substance Pyridalyl 179101-81-6 2,6-dichloro-4-(3,3-dichloroallyloxy)phenyl 3-[5-(trifluoromethyl)-2-pyridyloxy]propyl ether Pyridalyl C18H14Cl4F3NO3 C1=CC(=NC(=C1)OCCCOC2=C(C=C(C=C2Cl)OCC=C(Cl)Cl)Cl)C(F)(F)F InChI=1S/C18H14Cl4F3NO3/c19-12-9-11(27-8-5-15(21)22)10-13(20)17(12)29-7-2-6-28-16-4-1-3-14(26-16)18(23,24)25/h1,3-5,9-10H,2,6-8H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported no data with Negative RMS: The Netherlands Pyridalyl (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3240
+Pyridalyl 179101-81-6 single chemical entity Component is identical to the substance Pyridalyl 179101-81-6 2,6-dichloro-4-(3,3-dichloroallyloxy)phenyl 3-[5-(trifluoromethyl)-2-pyridyloxy]propyl ether Pyridalyl C18H14Cl4F3NO3 C1=CC(=NC(=C1)OCCCOC2=C(C=C(C=C2Cl)OCC=C(Cl)Cl)Cl)C(F)(F)F InChI=1S/C18H14Cl4F3NO3/c19-12-9-11(27-8-5-15(21)22)10-13(20)17(12)29-7-2-6-28-16-4-1-3-14(26-16)18(23,24)25/h1,3-5,9-10H,2,6-8H2 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data without Negative RMS: The Netherlands Pyridalyl (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3240
+Pyridalyl 179101-81-6 single chemical entity Component is identical to the substance Pyridalyl 179101-81-6 2,6-dichloro-4-(3,3-dichloroallyloxy)phenyl 3-[5-(trifluoromethyl)-2-pyridyloxy]propyl ether Pyridalyl C18H14Cl4F3NO3 C1=CC(=NC(=C1)OCCCOC2=C(C=C(C=C2Cl)OCC=C(Cl)Cl)Cl)C(F)(F)F InChI=1S/C18H14Cl4F3NO3/c19-12-9-11(27-8-5-15(21)22)10-13(20)17(12)29-7-2-6-28-16-4-1-3-14(26-16)18(23,24)25/h1,3-5,9-10H,2,6-8H2 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data with Positive RMS: The Netherlands Pyridalyl (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3240
+Pyridalyl 179101-81-6 single chemical entity Component is identical to the substance Pyridalyl 179101-81-6 2,6-dichloro-4-(3,3-dichloroallyloxy)phenyl 3-[5-(trifluoromethyl)-2-pyridyloxy]propyl ether Pyridalyl C18H14Cl4F3NO3 C1=CC(=NC(=C1)OCCCOC2=C(C=C(C=C2Cl)OCC=C(Cl)Cl)Cl)C(F)(F)F InChI=1S/C18H14Cl4F3NO3/c19-12-9-11(27-8-5-15(21)22)10-13(20)17(12)29-7-2-6-28-16-4-1-3-14(26-16)18(23,24)25/h1,3-5,9-10H,2,6-8H2 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 5 Male oral: unspecified 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The Netherlands Pyridalyl (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3240
+Pyridalyl 179101-81-6 single chemical entity Component is identical to the substance Pyridalyl 179101-81-6 2,6-dichloro-4-(3,3-dichloroallyloxy)phenyl 3-[5-(trifluoromethyl)-2-pyridyloxy]propyl ether Pyridalyl C18H14Cl4F3NO3 C1=CC(=NC(=C1)OCCCOC2=C(C=C(C=C2Cl)OCC=C(Cl)Cl)Cl)C(F)(F)F InChI=1S/C18H14Cl4F3NO3/c19-12-9-11(27-8-5-15(21)22)10-13(20)17(12)29-7-2-6-28-16-4-1-3-14(26-16)18(23,24)25/h1,3-5,9-10H,2,6-8H2 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 5 Male oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The Netherlands Pyridalyl (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3240
+Pyridalyl 179101-81-6 single chemical entity Component is identical to the substance Pyridalyl 179101-81-6 2,6-dichloro-4-(3,3-dichloroallyloxy)phenyl 3-[5-(trifluoromethyl)-2-pyridyloxy]propyl ether Pyridalyl C18H14Cl4F3NO3 C1=CC(=NC(=C1)OCCCOC2=C(C=C(C=C2Cl)OCC=C(Cl)Cl)Cl)C(F)(F)F InChI=1S/C18H14Cl4F3NO3/c19-12-9-11(27-8-5-15(21)22)10-13(20)17(12)29-7-2-6-28-16-4-1-3-14(26-16)18(23,24)25/h1,3-5,9-10H,2,6-8H2 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Sprague-Dawley 4 Male Not reported 16.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The Netherlands Pyridalyl (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3240
+Pyridalyl 179101-81-6 single chemical entity Component is identical to the substance Pyridalyl 179101-81-6 2,6-dichloro-4-(3,3-dichloroallyloxy)phenyl 3-[5-(trifluoromethyl)-2-pyridyloxy]propyl ether Pyridalyl C18H14Cl4F3NO3 C1=CC(=NC(=C1)OCCCOC2=C(C=C(C=C2Cl)OCC=C(Cl)Cl)Cl)C(F)(F)F InChI=1S/C18H14Cl4F3NO3/c19-12-9-11(27-8-5-15(21)22)10-13(20)17(12)29-7-2-6-28-16-4-1-3-14(26-16)18(23,24)25/h1,3-5,9-10H,2,6-8H2 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Sprague-Dawley 4 Male Not reported 4.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The Netherlands Pyridalyl (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3240
+Pyridalyl 179101-81-6 single chemical entity Component is a metabolite of the substance 5-(Trifluoromethyl)-2(1H)-pyridinone 33252-63-0 5-(Trifluoromethyl)-1H-pyridin-2-one Not in list C6H4F3NO C1=CC(=O)NC=C1C(F)(F)F InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: The Netherlands Pyridalyl (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3240
+Pyridalyl 179101-81-6 single chemical entity Component is a metabolite of the substance 5-(Trifluoromethyl)-2(1H)-pyridinone 33252-63-0 5-(Trifluoromethyl)-1H-pyridin-2-one Not in list C6H4F3NO C1=CC(=O)NC=C1C(F)(F)F InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Positive RMS: The Netherlands Pyridalyl (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3240
+Pyridalyl 179101-81-6 single chemical entity Component is a metabolite of the substance 5-(Trifluoromethyl)-2(1H)-pyridinone 33252-63-0 5-(Trifluoromethyl)-1H-pyridin-2-one Not in list C6H4F3NO C1=CC(=O)NC=C1C(F)(F)F InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: The Netherlands Pyridalyl (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3240
+Pyridalyl 179101-81-6 single chemical entity Component is a metabolite of the substance 5-(Trifluoromethyl)-2(1H)-pyridinone 33252-63-0 5-(Trifluoromethyl)-1H-pyridin-2-one Not in list C6H4F3NO C1=CC(=O)NC=C1C(F)(F)F InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: The Netherlands Pyridalyl (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3240
+Pyridalyl 179101-81-6 single chemical entity Component is a metabolite of the substance 5-(Trifluoromethyl)-2(1H)-pyridinone 33252-63-0 5-(Trifluoromethyl)-1H-pyridin-2-one Not in list C6H4F3NO C1=CC(=O)NC=C1C(F)(F)F InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: The Netherlands Pyridalyl (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3240
+Pyridalyl 179101-81-6 single chemical entity Component is a metabolite of the substance 5-(Trifluoromethyl)-2(1H)-pyridinone 33252-63-0 5-(Trifluoromethyl)-1H-pyridin-2-one Not in list C6H4F3NO C1=CC(=O)NC=C1C(F)(F)F InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: The Netherlands Pyridalyl (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3240
+Pyridalyl 179101-81-6 single chemical entity Component is a metabolite of the substance 5-(Trifluoromethyl)-2(1H)-pyridinone 33252-63-0 5-(Trifluoromethyl)-1H-pyridin-2-one Not in list C6H4F3NO C1=CC(=O)NC=C1C(F)(F)F InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: The Netherlands Pyridalyl (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3240
+Pyridalyl 179101-81-6 single chemical entity Component is a metabolite of the substance 5-(Trifluoromethyl)-2(1H)-pyridinone 33252-63-0 5-(Trifluoromethyl)-1H-pyridin-2-one Not in list C6H4F3NO C1=CC(=O)NC=C1C(F)(F)F InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Positive RMS: The Netherlands Pyridalyl (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3240
+Pyridalyl 179101-81-6 single chemical entity Component is a metabolite of the substance 5-(Trifluoromethyl)-2(1H)-pyridinone 33252-63-0 5-(Trifluoromethyl)-1H-pyridin-2-one Not in list C6H4F3NO C1=CC(=O)NC=C1C(F)(F)F InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Positive RMS: The Netherlands Pyridalyl (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3240
+Pyridalyl 179101-81-6 single chemical entity Component is a metabolite of the substance 5-(Trifluoromethyl)-2(1H)-pyridinone 33252-63-0 5-(Trifluoromethyl)-1H-pyridin-2-one Not in list C6H4F3NO C1=CC(=O)NC=C1C(F)(F)F InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Positive RMS: The Netherlands Pyridalyl (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3240
+Pyridalyl 179101-81-6 single chemical entity Component is a metabolite of the substance 5-(Trifluoromethyl)-2(1H)-pyridinone 33252-63-0 5-(Trifluoromethyl)-1H-pyridin-2-one Not in list C6H4F3NO C1=CC(=O)NC=C1C(F)(F)F InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data with Negative RMS: The Netherlands Pyridalyl (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3240
+Pyridalyl 179101-81-6 single chemical entity Component is a metabolite of the substance 5-(Trifluoromethyl)-2(1H)-pyridinone 33252-63-0 5-(Trifluoromethyl)-1H-pyridin-2-one Not in list C6H4F3NO C1=CC(=O)NC=C1C(F)(F)F InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data without Negative RMS: The Netherlands Pyridalyl (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3240
+Pyridalyl 179101-81-6 single chemical entity Component is a metabolite of the substance 5-(Trifluoromethyl)-2(1H)-pyridinone 33252-63-0 5-(Trifluoromethyl)-1H-pyridin-2-one Not in list C6H4F3NO C1=CC(=O)NC=C1C(F)(F)F InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data with Negative RMS: The Netherlands Pyridalyl (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3240
+Pyridalyl 179101-81-6 single chemical entity Component is a metabolite of the substance 5-(Trifluoromethyl)-2(1H)-pyridinone 33252-63-0 5-(Trifluoromethyl)-1H-pyridin-2-one Not in list C6H4F3NO C1=CC(=O)NC=C1C(F)(F)F InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data without Negative RMS: The Netherlands Pyridalyl (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3240
+Pyridalyl 179101-81-6 single chemical entity Component is a metabolite of the substance 5-(Trifluoromethyl)-2(1H)-pyridinone 33252-63-0 5-(Trifluoromethyl)-1H-pyridin-2-one Not in list C6H4F3NO C1=CC(=O)NC=C1C(F)(F)F InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Crj:CD(SD) 4 Male Not reported 2.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The Netherlands Pyridalyl (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3240
+Pyridalyl 179101-81-6 single chemical entity Component is a metabolite of the substance 5-(Trifluoromethyl)-2(1H)-pyridinone 33252-63-0 5-(Trifluoromethyl)-1H-pyridin-2-one Not in list C6H4F3NO C1=CC(=O)NC=C1C(F)(F)F InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Crj:CD(SD) 4 Male Not reported 16.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The Netherlands Pyridalyl (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3240
+Pyridalyl 179101-81-6 single chemical entity Component is a metabolite of the substance 3-hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one 3-hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one Not in list C6H4F3NO2 OC1=CC(=CNC1=O)C(F)(F)F InChI=1S/C6H4F3NO2/c7-6(8,9)3-1-4(11)5(12)10-2-3/h1-2,11H,(H,10,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Positive RMS: The Netherlands Pyridalyl (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3240
+Pyridalyl 179101-81-6 single chemical entity Component is a metabolite of the substance 3-hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one 3-hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one Not in list C6H4F3NO2 OC1=CC(=CNC1=O)C(F)(F)F InChI=1S/C6H4F3NO2/c7-6(8,9)3-1-4(11)5(12)10-2-3/h1-2,11H,(H,10,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: The Netherlands Pyridalyl (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3240
+Pyridalyl 179101-81-6 single chemical entity Component is a metabolite of the substance 3-hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one 3-hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one Not in list C6H4F3NO2 OC1=CC(=CNC1=O)C(F)(F)F InChI=1S/C6H4F3NO2/c7-6(8,9)3-1-4(11)5(12)10-2-3/h1-2,11H,(H,10,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Positive RMS: The Netherlands Pyridalyl (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3240
+Pyridalyl 179101-81-6 single chemical entity Component is a metabolite of the substance 3-hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one 3-hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one Not in list C6H4F3NO2 OC1=CC(=CNC1=O)C(F)(F)F InChI=1S/C6H4F3NO2/c7-6(8,9)3-1-4(11)5(12)10-2-3/h1-2,11H,(H,10,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: The Netherlands Pyridalyl (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3240
+Pyridalyl 179101-81-6 single chemical entity Component is a metabolite of the substance 3-hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one 3-hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one Not in list C6H4F3NO2 OC1=CC(=CNC1=O)C(F)(F)F InChI=1S/C6H4F3NO2/c7-6(8,9)3-1-4(11)5(12)10-2-3/h1-2,11H,(H,10,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: The Netherlands Pyridalyl (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3240
+Pyridalyl 179101-81-6 single chemical entity Component is a metabolite of the substance 3-hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one 3-hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one Not in list C6H4F3NO2 OC1=CC(=CNC1=O)C(F)(F)F InChI=1S/C6H4F3NO2/c7-6(8,9)3-1-4(11)5(12)10-2-3/h1-2,11H,(H,10,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Positive RMS: The Netherlands Pyridalyl (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3240
+Pyridalyl 179101-81-6 single chemical entity Component is a metabolite of the substance 3-hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one 3-hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one Not in list C6H4F3NO2 OC1=CC(=CNC1=O)C(F)(F)F InChI=1S/C6H4F3NO2/c7-6(8,9)3-1-4(11)5(12)10-2-3/h1-2,11H,(H,10,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Positive RMS: The Netherlands Pyridalyl (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3240
+Pyridalyl 179101-81-6 single chemical entity Component is a metabolite of the substance 3-hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one 3-hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one Not in list C6H4F3NO2 OC1=CC(=CNC1=O)C(F)(F)F InChI=1S/C6H4F3NO2/c7-6(8,9)3-1-4(11)5(12)10-2-3/h1-2,11H,(H,10,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: The Netherlands Pyridalyl (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3240
+Pyridalyl 179101-81-6 single chemical entity Component is a metabolite of the substance 3-hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one 3-hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one Not in list C6H4F3NO2 OC1=CC(=CNC1=O)C(F)(F)F InChI=1S/C6H4F3NO2/c7-6(8,9)3-1-4(11)5(12)10-2-3/h1-2,11H,(H,10,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: The Netherlands Pyridalyl (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3240
+Pyridalyl 179101-81-6 single chemical entity Component is a metabolite of the substance 3-hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one 3-hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one Not in list C6H4F3NO2 OC1=CC(=CNC1=O)C(F)(F)F InChI=1S/C6H4F3NO2/c7-6(8,9)3-1-4(11)5(12)10-2-3/h1-2,11H,(H,10,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Positive RMS: The Netherlands Pyridalyl (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3240
+Pyridalyl 179101-81-6 single chemical entity Component is a metabolite of the substance 3-hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one 3-hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one Not in list C6H4F3NO2 OC1=CC(=CNC1=O)C(F)(F)F InChI=1S/C6H4F3NO2/c7-6(8,9)3-1-4(11)5(12)10-2-3/h1-2,11H,(H,10,12) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data without Negative RMS: The Netherlands Pyridalyl (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3240
+Pyridalyl 179101-81-6 single chemical entity Component is a metabolite of the substance 3-hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one 3-hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one Not in list C6H4F3NO2 OC1=CC(=CNC1=O)C(F)(F)F InChI=1S/C6H4F3NO2/c7-6(8,9)3-1-4(11)5(12)10-2-3/h1-2,11H,(H,10,12) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data with Negative RMS: The Netherlands Pyridalyl (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3240
+Pyridalyl 179101-81-6 single chemical entity Component is a metabolite of the substance 3-hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one 3-hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one Not in list C6H4F3NO2 OC1=CC(=CNC1=O)C(F)(F)F InChI=1S/C6H4F3NO2/c7-6(8,9)3-1-4(11)5(12)10-2-3/h1-2,11H,(H,10,12) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data without Positive RMS: The Netherlands Pyridalyl (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3240
+Pyridalyl 179101-81-6 single chemical entity Component is a metabolite of the substance 3-hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one 3-hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one Not in list C6H4F3NO2 OC1=CC(=CNC1=O)C(F)(F)F InChI=1S/C6H4F3NO2/c7-6(8,9)3-1-4(11)5(12)10-2-3/h1-2,11H,(H,10,12) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data with Negative RMS: The Netherlands Pyridalyl (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3240
+Pyridalyl 179101-81-6 single chemical entity Component is a metabolite of the substance 3-hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one 3-hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one Not in list C6H4F3NO2 OC1=CC(=CNC1=O)C(F)(F)F InChI=1S/C6H4F3NO2/c7-6(8,9)3-1-4(11)5(12)10-2-3/h1-2,11H,(H,10,12) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 5 Male oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The Netherlands Pyridalyl (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3240
+Pyridalyl 179101-81-6 single chemical entity Component is a metabolite of the substance 3-hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one 3-hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one Not in list C6H4F3NO2 OC1=CC(=CNC1=O)C(F)(F)F InChI=1S/C6H4F3NO2/c7-6(8,9)3-1-4(11)5(12)10-2-3/h1-2,11H,(H,10,12) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 5 Male oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The Netherlands Pyridalyl (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3240
+Oryzalin 242-777-0 19044-88-3 single chemical entity Component is identical to the substance Oryzalin 242-777-0 19044-88-3 4-(dipropylamino)-3,5-dinitrobenzenesulfonamide Oryzalin C12H18N4O6S [O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Oryzalin (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin. 03Sep2010 2010 doi:10.2903/j.efsa.2010.1707
+Oryzalin 242-777-0 19044-88-3 single chemical entity Component is identical to the substance Oryzalin 242-777-0 19044-88-3 4-(dipropylamino)-3,5-dinitrobenzenesulfonamide Oryzalin C12H18N4O6S [O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Oryzalin (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin. 03Sep2010 2010 doi:10.2903/j.efsa.2010.1707
+Oryzalin 242-777-0 19044-88-3 single chemical entity Component is identical to the substance Oryzalin 242-777-0 19044-88-3 4-(dipropylamino)-3,5-dinitrobenzenesulfonamide Oryzalin C12H18N4O6S [O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Oryzalin (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin. 03Sep2010 2010 doi:10.2903/j.efsa.2010.1707
+Oryzalin 242-777-0 19044-88-3 single chemical entity Component is identical to the substance Oryzalin 242-777-0 19044-88-3 4-(dipropylamino)-3,5-dinitrobenzenesulfonamide Oryzalin C12H18N4O6S [O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: France Oryzalin (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin. 03Sep2010 2010 doi:10.2903/j.efsa.2010.1707
+Oryzalin 242-777-0 19044-88-3 single chemical entity Component is identical to the substance Oryzalin 242-777-0 19044-88-3 4-(dipropylamino)-3,5-dinitrobenzenesulfonamide Oryzalin C12H18N4O6S [O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Oryzalin (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin. 03Sep2010 2010 doi:10.2903/j.efsa.2010.1707
+Oryzalin 242-777-0 19044-88-3 single chemical entity Component is identical to the substance Oryzalin 242-777-0 19044-88-3 4-(dipropylamino)-3,5-dinitrobenzenesulfonamide Oryzalin C12H18N4O6S [O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Oryzalin (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin. 03Sep2010 2010 doi:10.2903/j.efsa.2010.1707
+Oryzalin 242-777-0 19044-88-3 single chemical entity Component is identical to the substance Oryzalin 242-777-0 19044-88-3 4-(dipropylamino)-3,5-dinitrobenzenesulfonamide Oryzalin C12H18N4O6S [O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: France Oryzalin (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin. 03Sep2010 2010 doi:10.2903/j.efsa.2010.1707
+Oryzalin 242-777-0 19044-88-3 single chemical entity Component is identical to the substance Oryzalin 242-777-0 19044-88-3 4-(dipropylamino)-3,5-dinitrobenzenesulfonamide Oryzalin C12H18N4O6S [O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Oryzalin (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin. 03Sep2010 2010 doi:10.2903/j.efsa.2010.1707
+Oryzalin 242-777-0 19044-88-3 single chemical entity Component is identical to the substance Oryzalin 242-777-0 19044-88-3 4-(dipropylamino)-3,5-dinitrobenzenesulfonamide Oryzalin C12H18N4O6S [O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Oryzalin (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin. 03Sep2010 2010 doi:10.2903/j.efsa.2010.1707
+Oryzalin 242-777-0 19044-88-3 single chemical entity Component is identical to the substance Oryzalin 242-777-0 19044-88-3 4-(dipropylamino)-3,5-dinitrobenzenesulfonamide Oryzalin C12H18N4O6S [O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Oryzalin (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin. 03Sep2010 2010 doi:10.2903/j.efsa.2010.1707
+Oryzalin 242-777-0 19044-88-3 single chemical entity Component is identical to the substance Oryzalin 242-777-0 19044-88-3 4-(dipropylamino)-3,5-dinitrobenzenesulfonamide Oryzalin C12H18N4O6S [O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Oryzalin (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin. 03Sep2010 2010 doi:10.2903/j.efsa.2010.1707
+Oryzalin 242-777-0 19044-88-3 single chemical entity Component is identical to the substance Oryzalin 242-777-0 19044-88-3 4-(dipropylamino)-3,5-dinitrobenzenesulfonamide Oryzalin C12H18N4O6S [O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Oryzalin (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin. 03Sep2010 2010 doi:10.2903/j.efsa.2010.1707
+Oryzalin 242-777-0 19044-88-3 single chemical entity Component is identical to the substance Oryzalin 242-777-0 19044-88-3 4-(dipropylamino)-3,5-dinitrobenzenesulfonamide Oryzalin C12H18N4O6S [O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Oryzalin (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin. 03Sep2010 2010 doi:10.2903/j.efsa.2010.1707
+Oryzalin 242-777-0 19044-88-3 single chemical entity Component is identical to the substance Oryzalin 242-777-0 19044-88-3 4-(dipropylamino)-3,5-dinitrobenzenesulfonamide Oryzalin C12H18N4O6S [O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Oryzalin (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin. 03Sep2010 2010 doi:10.2903/j.efsa.2010.1707
+Oryzalin 242-777-0 19044-88-3 single chemical entity Component is identical to the substance Oryzalin 242-777-0 19044-88-3 4-(dipropylamino)-3,5-dinitrobenzenesulfonamide Oryzalin C12H18N4O6S [O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: France Oryzalin (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin. 03Sep2010 2010 doi:10.2903/j.efsa.2010.1707
+Oryzalin 242-777-0 19044-88-3 single chemical entity Component is identical to the substance Oryzalin 242-777-0 19044-88-3 4-(dipropylamino)-3,5-dinitrobenzenesulfonamide Oryzalin C12H18N4O6S [O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Oryzalin (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin. 03Sep2010 2010 doi:10.2903/j.efsa.2010.1707
+Oryzalin 242-777-0 19044-88-3 single chemical entity Component is identical to the substance Oryzalin 242-777-0 19044-88-3 4-(dipropylamino)-3,5-dinitrobenzenesulfonamide Oryzalin C12H18N4O6S [O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Oryzalin (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin. 03Sep2010 2010 doi:10.2903/j.efsa.2010.1707
+Oryzalin 242-777-0 19044-88-3 single chemical entity Component is identical to the substance Oryzalin 242-777-0 19044-88-3 4-(dipropylamino)-3,5-dinitrobenzenesulfonamide Oryzalin C12H18N4O6S [O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: France Oryzalin (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin. 03Sep2010 2010 doi:10.2903/j.efsa.2010.1707
+Oryzalin 242-777-0 19044-88-3 single chemical entity Component is identical to the substance Oryzalin 242-777-0 19044-88-3 4-(dipropylamino)-3,5-dinitrobenzenesulfonamide Oryzalin C12H18N4O6S [O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Oryzalin (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin. 03Sep2010 2010 doi:10.2903/j.efsa.2010.1707
+Oryzalin 242-777-0 19044-88-3 single chemical entity Component is identical to the substance Oryzalin 242-777-0 19044-88-3 4-(dipropylamino)-3,5-dinitrobenzenesulfonamide Oryzalin C12H18N4O6S [O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Oryzalin (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin. 03Sep2010 2010 doi:10.2903/j.efsa.2010.1707
+Oryzalin 242-777-0 19044-88-3 single chemical entity Component is identical to the substance Oryzalin 242-777-0 19044-88-3 4-(dipropylamino)-3,5-dinitrobenzenesulfonamide Oryzalin C12H18N4O6S [O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: France Oryzalin (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin. 03Sep2010 2010 doi:10.2903/j.efsa.2010.1707
+Oryzalin 242-777-0 19044-88-3 single chemical entity Component is identical to the substance Oryzalin 242-777-0 19044-88-3 4-(dipropylamino)-3,5-dinitrobenzenesulfonamide Oryzalin C12H18N4O6S [O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: France Oryzalin (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin. 03Sep2010 2010 doi:10.2903/j.efsa.2010.1707
+Oryzalin 242-777-0 19044-88-3 single chemical entity Component is identical to the substance Oryzalin 242-777-0 19044-88-3 4-(dipropylamino)-3,5-dinitrobenzenesulfonamide Oryzalin C12H18N4O6S [O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22) organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vivo No guideline available Not reported Not applicable Acceptable Hamster (as animal) Chinese 15 Female intraperitoneal 2.0000000000 h yes, concurrent vehicle not applicable Positive RMS: France Oryzalin (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin. 03Sep2010 2010 doi:10.2903/j.efsa.2010.1707
+Oryzalin 242-777-0 19044-88-3 single chemical entity Component is identical to the substance Oryzalin 242-777-0 19044-88-3 4-(dipropylamino)-3,5-dinitrobenzenesulfonamide Oryzalin C12H18N4O6S [O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 72.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: France Oryzalin (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin. 03Sep2010 2010 doi:10.2903/j.efsa.2010.1707
+Oryzalin 242-777-0 19044-88-3 single chemical entity Component is identical to the substance Oryzalin 242-777-0 19044-88-3 4-(dipropylamino)-3,5-dinitrobenzenesulfonamide Oryzalin C12H18N4O6S [O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: France Oryzalin (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin. 03Sep2010 2010 doi:10.2903/j.efsa.2010.1707
+Oryzalin 242-777-0 19044-88-3 single chemical entity Component is identical to the substance Oryzalin 242-777-0 19044-88-3 4-(dipropylamino)-3,5-dinitrobenzenesulfonamide Oryzalin C12H18N4O6S [O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: France Oryzalin (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin. 03Sep2010 2010 doi:10.2903/j.efsa.2010.1707
+Oryzalin 242-777-0 19044-88-3 single chemical entity Component is identical to the substance Oryzalin 242-777-0 19044-88-3 4-(dipropylamino)-3,5-dinitrobenzenesulfonamide Oryzalin C12H18N4O6S [O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22) organic compound Other Other chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) Yes Acceptable Rat (as animal) Wistar 10 Male oral: gavage yes, concurrent vehicle not applicable Negative RMS: France Oryzalin (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin. 03Sep2010 2010 doi:10.2903/j.efsa.2010.1707
+Oryzalin 242-777-0 19044-88-3 single chemical entity Component is identical to the substance Oryzalin 242-777-0 19044-88-3 4-(dipropylamino)-3,5-dinitrobenzenesulfonamide Oryzalin C12H18N4O6S [O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22) organic compound Other Other chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) Yes Acceptable Rat (as animal) Wistar 15 Male oral: gavage 5.0000000000 D yes, concurrent vehicle not applicable Negative RMS: France Oryzalin (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin. 03Sep2010 2010 doi:10.2903/j.efsa.2010.1707
+Oryzalin 242-777-0 19044-88-3 single chemical entity Component is identical to the substance Oryzalin 242-777-0 19044-88-3 4-(dipropylamino)-3,5-dinitrobenzenesulfonamide Oryzalin C12H18N4O6S [O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Oryzalin (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin. 03Sep2010 2010 doi:10.2903/j.efsa.2010.1707
+Oryzalin 242-777-0 19044-88-3 single chemical entity Component is identical to the substance Oryzalin 242-777-0 19044-88-3 4-(dipropylamino)-3,5-dinitrobenzenesulfonamide Oryzalin C12H18N4O6S [O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Oryzalin (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin. 03Sep2010 2010 doi:10.2903/j.efsa.2010.1707
+Oryzalin 242-777-0 19044-88-3 single chemical entity Component is identical to the substance Oryzalin 242-777-0 19044-88-3 4-(dipropylamino)-3,5-dinitrobenzenesulfonamide Oryzalin C12H18N4O6S [O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: France Oryzalin (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin. 03Sep2010 2010 doi:10.2903/j.efsa.2010.1707
+Oryzalin 242-777-0 19044-88-3 single chemical entity Component is identical to the substance Oryzalin 242-777-0 19044-88-3 4-(dipropylamino)-3,5-dinitrobenzenesulfonamide Oryzalin C12H18N4O6S [O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Oryzalin (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin. 03Sep2010 2010 doi:10.2903/j.efsa.2010.1707
+Oryzalin 242-777-0 19044-88-3 single chemical entity Component is identical to the substance Oryzalin 242-777-0 19044-88-3 4-(dipropylamino)-3,5-dinitrobenzenesulfonamide Oryzalin C12H18N4O6S [O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Oryzalin (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin. 03Sep2010 2010 doi:10.2903/j.efsa.2010.1707
+Oryzalin 242-777-0 19044-88-3 single chemical entity Component is identical to the substance Oryzalin 242-777-0 19044-88-3 4-(dipropylamino)-3,5-dinitrobenzenesulfonamide Oryzalin C12H18N4O6S [O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Oryzalin (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin. 03Sep2010 2010 doi:10.2903/j.efsa.2010.1707
+Oryzalin 242-777-0 19044-88-3 single chemical entity Component is identical to the substance Oryzalin 242-777-0 19044-88-3 4-(dipropylamino)-3,5-dinitrobenzenesulfonamide Oryzalin C12H18N4O6S [O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Oryzalin (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin. 03Sep2010 2010 doi:10.2903/j.efsa.2010.1707
+Oryzalin 242-777-0 19044-88-3 single chemical entity Component is identical to the substance Oryzalin 242-777-0 19044-88-3 4-(dipropylamino)-3,5-dinitrobenzenesulfonamide Oryzalin C12H18N4O6S [O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Oryzalin (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin. 03Sep2010 2010 doi:10.2903/j.efsa.2010.1707
+Oryzalin 242-777-0 19044-88-3 single chemical entity Component is identical to the substance Oryzalin 242-777-0 19044-88-3 4-(dipropylamino)-3,5-dinitrobenzenesulfonamide Oryzalin C12H18N4O6S [O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: France Oryzalin (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin. 03Sep2010 2010 doi:10.2903/j.efsa.2010.1707
+Oryzalin 242-777-0 19044-88-3 single chemical entity Component is identical to the substance Oryzalin 242-777-0 19044-88-3 4-(dipropylamino)-3,5-dinitrobenzenesulfonamide Oryzalin C12H18N4O6S [O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Oryzalin (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin. 03Sep2010 2010 doi:10.2903/j.efsa.2010.1707
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Positive RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Positive RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Positive RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Positive RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Positive RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Positive RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Positive RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Positive RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Positive RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Positive RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Positive RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Positive RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is identical to the substance Lambda-cyhalothrin 415-130-7 91465-08-6 [Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate Lambda-Cyhalothrin C23H19ClF3NO3 C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1 organic representative isomer ChemIDPlus Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is identical to the substance Lambda-cyhalothrin 415-130-7 91465-08-6 [Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate Lambda-Cyhalothrin C23H19ClF3NO3 C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1 organic representative isomer ChemIDPlus Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is identical to the substance Lambda-cyhalothrin 415-130-7 91465-08-6 [Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate Lambda-Cyhalothrin C23H19ClF3NO3 C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1 organic representative isomer ChemIDPlus Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is identical to the substance Lambda-cyhalothrin 415-130-7 91465-08-6 [Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate Lambda-Cyhalothrin C23H19ClF3NO3 C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1 organic representative isomer ChemIDPlus Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is identical to the substance Lambda-cyhalothrin 415-130-7 91465-08-6 [Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate Lambda-Cyhalothrin C23H19ClF3NO3 C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1 organic representative isomer ChemIDPlus Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is identical to the substance Lambda-cyhalothrin 415-130-7 91465-08-6 [Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate Lambda-Cyhalothrin C23H19ClF3NO3 C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1 organic representative isomer ChemIDPlus Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is identical to the substance Lambda-cyhalothrin 415-130-7 91465-08-6 [Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate Lambda-Cyhalothrin C23H19ClF3NO3 C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1 organic representative isomer ChemIDPlus Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is identical to the substance Lambda-cyhalothrin 415-130-7 91465-08-6 [Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate Lambda-Cyhalothrin C23H19ClF3NO3 C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1 organic representative isomer ChemIDPlus Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is identical to the substance Lambda-cyhalothrin 415-130-7 91465-08-6 [Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate Lambda-Cyhalothrin C23H19ClF3NO3 C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1 organic representative isomer ChemIDPlus Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is identical to the substance Lambda-cyhalothrin 415-130-7 91465-08-6 [Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate Lambda-Cyhalothrin C23H19ClF3NO3 C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1 organic representative isomer ChemIDPlus Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is identical to the substance Lambda-cyhalothrin 415-130-7 91465-08-6 [Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate Lambda-Cyhalothrin C23H19ClF3NO3 C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1 organic representative isomer ChemIDPlus Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is identical to the substance Lambda-cyhalothrin 415-130-7 91465-08-6 [Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate Lambda-Cyhalothrin C23H19ClF3NO3 C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1 organic representative isomer ChemIDPlus Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is identical to the substance Lambda-cyhalothrin 415-130-7 91465-08-6 [Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate Lambda-Cyhalothrin C23H19ClF3NO3 C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1 organic representative isomer ChemIDPlus Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is identical to the substance Lambda-cyhalothrin 415-130-7 91465-08-6 [Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate Lambda-Cyhalothrin C23H19ClF3NO3 C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1 organic representative isomer ChemIDPlus Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is identical to the substance Lambda-cyhalothrin 415-130-7 91465-08-6 [Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate Lambda-Cyhalothrin C23H19ClF3NO3 C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1 organic representative isomer ChemIDPlus Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is identical to the substance Lambda-cyhalothrin 415-130-7 91465-08-6 [Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate Lambda-Cyhalothrin C23H19ClF3NO3 C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1 organic representative isomer ChemIDPlus Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is identical to the substance Lambda-cyhalothrin 415-130-7 91465-08-6 [Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate Lambda-Cyhalothrin C23H19ClF3NO3 C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1 organic representative isomer ChemIDPlus Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is identical to the substance Lambda-cyhalothrin 415-130-7 91465-08-6 [Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate Lambda-Cyhalothrin C23H19ClF3NO3 C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1 organic representative isomer ChemIDPlus Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is identical to the substance Lambda-cyhalothrin 415-130-7 91465-08-6 [Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate Lambda-Cyhalothrin C23H19ClF3NO3 C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1 organic representative isomer ChemIDPlus Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is identical to the substance Lambda-cyhalothrin 415-130-7 91465-08-6 [Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate Lambda-Cyhalothrin C23H19ClF3NO3 C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1 organic representative isomer ChemIDPlus Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is identical to the substance Lambda-cyhalothrin 415-130-7 91465-08-6 [Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate Lambda-Cyhalothrin C23H19ClF3NO3 C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1 organic representative isomer ChemIDPlus Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is identical to the substance Lambda-cyhalothrin 415-130-7 91465-08-6 [Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate Lambda-Cyhalothrin C23H19ClF3NO3 C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1 organic representative isomer ChemIDPlus Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is identical to the substance Lambda-cyhalothrin 415-130-7 91465-08-6 [Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate Lambda-Cyhalothrin C23H19ClF3NO3 C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1 organic representative isomer ChemIDPlus Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is identical to the substance Lambda-cyhalothrin 415-130-7 91465-08-6 [Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate Lambda-Cyhalothrin C23H19ClF3NO3 C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1 organic representative isomer ChemIDPlus Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is identical to the substance Lambda-cyhalothrin 415-130-7 91465-08-6 [Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate Lambda-Cyhalothrin C23H19ClF3NO3 C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1 organic representative isomer ChemIDPlus Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is identical to the substance Lambda-cyhalothrin 415-130-7 91465-08-6 [Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate Lambda-Cyhalothrin C23H19ClF3NO3 C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1 organic representative isomer ChemIDPlus Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is identical to the substance Lambda-cyhalothrin 415-130-7 91465-08-6 [Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate Lambda-Cyhalothrin C23H19ClF3NO3 C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1 organic representative isomer ChemIDPlus Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is identical to the substance Lambda-cyhalothrin 415-130-7 91465-08-6 [Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate Lambda-Cyhalothrin C23H19ClF3NO3 C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1 organic representative isomer ChemIDPlus Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is identical to the substance Lambda-cyhalothrin 415-130-7 91465-08-6 [Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate Lambda-Cyhalothrin C23H19ClF3NO3 C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1 organic representative isomer ChemIDPlus Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is identical to the substance Lambda-cyhalothrin 415-130-7 91465-08-6 [Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate Lambda-Cyhalothrin C23H19ClF3NO3 C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1 organic representative isomer ChemIDPlus Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is identical to the substance Lambda-cyhalothrin 415-130-7 91465-08-6 [Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate Lambda-Cyhalothrin C23H19ClF3NO3 C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1 organic representative isomer ChemIDPlus Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is identical to the substance Lambda-cyhalothrin 415-130-7 91465-08-6 [Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate Lambda-Cyhalothrin C23H19ClF3NO3 C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1 organic representative isomer ChemIDPlus Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is identical to the substance Lambda-cyhalothrin 415-130-7 91465-08-6 [Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate Lambda-Cyhalothrin C23H19ClF3NO3 C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1 organic representative isomer ChemIDPlus Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is identical to the substance Lambda-cyhalothrin 415-130-7 91465-08-6 [Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate Lambda-Cyhalothrin C23H19ClF3NO3 C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1 organic representative isomer ChemIDPlus Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is identical to the substance Lambda-cyhalothrin 415-130-7 91465-08-6 [Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate Lambda-Cyhalothrin C23H19ClF3NO3 C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1 organic representative isomer ChemIDPlus Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes without Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is identical to the substance Lambda-cyhalothrin 415-130-7 91465-08-6 [Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate Lambda-Cyhalothrin C23H19ClF3NO3 C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1 organic representative isomer ChemIDPlus Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes with Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is identical to the substance Lambda-cyhalothrin 415-130-7 91465-08-6 [Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate Lambda-Cyhalothrin C23H19ClF3NO3 C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1 organic representative isomer ChemIDPlus Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is identical to the substance Lambda-cyhalothrin 415-130-7 91465-08-6 [Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate Lambda-Cyhalothrin C23H19ClF3NO3 C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1 organic representative isomer ChemIDPlus Other DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vitro No guideline available Not reported Not applicable Acceptable House mouse (as animal) RAW 264.7 Not reported no data no data Positive RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is identical to the substance Lambda-cyhalothrin 415-130-7 91465-08-6 [Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate Lambda-Cyhalothrin C23H19ClF3NO3 C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1 organic representative isomer ChemIDPlus Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) C57BL 30 Male/Female intraperitoneal 72.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is identical to the substance Lambda-cyhalothrin 415-130-7 91465-08-6 [Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate Lambda-Cyhalothrin C23H19ClF3NO3 C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1 organic representative isomer ChemIDPlus Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) C57BL 30 Male/Female intraperitoneal 24.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is identical to the substance Lambda-cyhalothrin 415-130-7 91465-08-6 [Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate Lambda-Cyhalothrin C23H19ClF3NO3 C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1 organic representative isomer ChemIDPlus Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) C57BL 30 Male/Female intraperitoneal 48.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid (1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid Not in list C9H10ClF3O2 Cl\C(=C/[C@H]1[C@@H](C(=O)O)C1(C)C)C(F)(F)F InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid (1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid Not in list C9H10ClF3O2 Cl\C(=C/[C@H]1[C@@H](C(=O)O)C1(C)C)C(F)(F)F InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid (1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid Not in list C9H10ClF3O2 Cl\C(=C/[C@H]1[C@@H](C(=O)O)C1(C)C)C(F)(F)F InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid (1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid Not in list C9H10ClF3O2 Cl\C(=C/[C@@H]1[C@H](C(=O)O)C1(C)C)C(F)(F)F InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid (1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid Not in list C9H10ClF3O2 Cl\C(=C/[C@H]1[C@@H](C(=O)O)C1(C)C)C(F)(F)F InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid (1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid Not in list C9H10ClF3O2 Cl\C(=C/[C@@H]1[C@H](C(=O)O)C1(C)C)C(F)(F)F InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid (1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid Not in list C9H10ClF3O2 Cl\C(=C/[C@@H]1[C@H](C(=O)O)C1(C)C)C(F)(F)F InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid (1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid Not in list C9H10ClF3O2 Cl\C(=C/[C@H]1[C@@H](C(=O)O)C1(C)C)C(F)(F)F InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid (1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid Not in list C9H10ClF3O2 Cl\C(=C/[C@@H]1[C@H](C(=O)O)C1(C)C)C(F)(F)F InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid (1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid Not in list C9H10ClF3O2 Cl\C(=C/[C@@H]1[C@H](C(=O)O)C1(C)C)C(F)(F)F InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid (1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid Not in list C9H10ClF3O2 Cl\C(=C/[C@H]1[C@@H](C(=O)O)C1(C)C)C(F)(F)F InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid (1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid Not in list C9H10ClF3O2 Cl\C(=C/[C@@H]1[C@H](C(=O)O)C1(C)C)C(F)(F)F InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid (1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid Not in list C9H10ClF3O2 Cl\C(=C/[C@H]1[C@@H](C(=O)O)C1(C)C)C(F)(F)F InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid (1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid Not in list C9H10ClF3O2 Cl\C(=C/[C@@H]1[C@H](C(=O)O)C1(C)C)C(F)(F)F InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid (1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid Not in list C9H10ClF3O2 Cl\C(=C/[C@@H]1[C@H](C(=O)O)C1(C)C)C(F)(F)F InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid (1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid Not in list C9H10ClF3O2 Cl\C(=C/[C@H]1[C@@H](C(=O)O)C1(C)C)C(F)(F)F InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid (1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid Not in list C9H10ClF3O2 Cl\C(=C/[C@@H]1[C@H](C(=O)O)C1(C)C)C(F)(F)F InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid (1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid Not in list C9H10ClF3O2 Cl\C(=C/[C@@H]1[C@H](C(=O)O)C1(C)C)C(F)(F)F InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid (1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid Not in list C9H10ClF3O2 Cl\C(=C/[C@H]1[C@@H](C(=O)O)C1(C)C)C(F)(F)F InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid (1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid Not in list C9H10ClF3O2 Cl\C(=C/[C@H]1[C@@H](C(=O)O)C1(C)C)C(F)(F)F InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid (1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid Not in list C9H10ClF3O2 Cl\C(=C/[C@H]1[C@@H](C(=O)O)C1(C)C)C(F)(F)F InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid (1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid Not in list C9H10ClF3O2 Cl\C(=C/[C@@H]1[C@H](C(=O)O)C1(C)C)C(F)(F)F InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid (1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid Not in list C9H10ClF3O2 Cl\C(=C/[C@@H]1[C@H](C(=O)O)C1(C)C)C(F)(F)F InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid (1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid Not in list C9H10ClF3O2 Cl\C(=C/[C@H]1[C@@H](C(=O)O)C1(C)C)C(F)(F)F InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid (1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid Not in list C9H10ClF3O2 Cl\C(=C/[C@@H]1[C@H](C(=O)O)C1(C)C)C(F)(F)F InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid (1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid Not in list C9H10ClF3O2 Cl\C(=C/[C@@H]1[C@H](C(=O)O)C1(C)C)C(F)(F)F InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid (1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid Not in list C9H10ClF3O2 Cl\C(=C/[C@H]1[C@@H](C(=O)O)C1(C)C)C(F)(F)F InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid (1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid Not in list C9H10ClF3O2 Cl\C(=C/[C@H]1[C@@H](C(=O)O)C1(C)C)C(F)(F)F InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid (1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid Not in list C9H10ClF3O2 Cl\C(=C/[C@@H]1[C@H](C(=O)O)C1(C)C)C(F)(F)F InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid (1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid Not in list C9H10ClF3O2 Cl\C(=C/[C@H]1[C@@H](C(=O)O)C1(C)C)C(F)(F)F InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid (1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid Not in list C9H10ClF3O2 Cl\C(=C/[C@@H]1[C@H](C(=O)O)C1(C)C)C(F)(F)F InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid (1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid Not in list C9H10ClF3O2 Cl\C(=C/[C@H]1[C@@H](C(=O)O)C1(C)C)C(F)(F)F InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid (1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid Not in list C9H10ClF3O2 Cl\C(=C/[C@@H]1[C@H](C(=O)O)C1(C)C)C(F)(F)F InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid (1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid Not in list C9H10ClF3O2 Cl\C(=C/[C@@H]1[C@H](C(=O)O)C1(C)C)C(F)(F)F InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid (1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid Not in list C9H10ClF3O2 Cl\C(=C/[C@H]1[C@@H](C(=O)O)C1(C)C)C(F)(F)F InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid (1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid Not in list C9H10ClF3O2 Cl\C(=C/[C@@H]1[C@H](C(=O)O)C1(C)C)C(F)(F)F InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid (1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid Not in list C9H10ClF3O2 Cl\C(=C/[C@H]1[C@@H](C(=O)O)C1(C)C)C(F)(F)F InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid (1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid Not in list C9H10ClF3O2 Cl\C(=C/[C@H]1[C@@H](C(=O)O)C1(C)C)C(F)(F)F InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid (1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid Not in list C9H10ClF3O2 Cl\C(=C/[C@@H]1[C@H](C(=O)O)C1(C)C)C(F)(F)F InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid (1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid Not in list C9H10ClF3O2 Cl\C(=C/[C@H]1[C@@H](C(=O)O)C1(C)C)C(F)(F)F InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid (1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid Not in list C9H10ClF3O2 Cl\C(=C/[C@@H]1[C@H](C(=O)O)C1(C)C)C(F)(F)F InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m1/s1 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid (1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid Not in list C9H10ClF3O2 Cl\C(=C/[C@H]1[C@@H](C(=O)O)C1(C)C)C(F)(F)F InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m0/s1 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid (1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid Not in list C9H10ClF3O2 Cl\C(=C/[C@@H]1[C@H](C(=O)O)C1(C)C)C(F)(F)F InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m1/s1 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid (1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid Not in list C9H10ClF3O2 Cl\C(=C/[C@H]1[C@@H](C(=O)O)C1(C)C)C(F)(F)F InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m0/s1 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid (1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid Not in list C9H10ClF3O2 Cl\C(=C/[C@@H]1[C@H](C(=O)O)C1(C)C)C(F)(F)F InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m1/s1 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes without Positive RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid (1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid Not in list C9H10ClF3O2 Cl\C(=C/[C@@H]1[C@H](C(=O)O)C1(C)C)C(F)(F)F InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m1/s1 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes with Positive RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid (1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid Not in list C9H10ClF3O2 Cl\C(=C/[C@H]1[C@@H](C(=O)O)C1(C)C)C(F)(F)F InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m0/s1 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes without Positive RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid (1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid Not in list C9H10ClF3O2 Cl\C(=C/[C@H]1[C@@H](C(=O)O)C1(C)C)C(F)(F)F InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m0/s1 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes with Positive RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (1RS,3RS)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylate 2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropane-1-carboxylate Not in list C23H21ClF3NO4 Cl\C(=C/C3C(C(=O)OC(c2cccc(Oc1ccccc1)c2)C(N)=O)C3(C)C)C(F)(F)F InChI=1S/C23H21ClF3NO4/c1-22(2)16(12-17(24)23(25,26)27)18(22)21(30)32-19(20(28)29)13-7-6-10-15(11-13)31-14-8-4-3-5-9-14/h3-12,16,18-19H,1-2H3,(H2,28,29)/b17-12- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (1RS,3RS)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylate 2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropane-1-carboxylate Not in list C23H21ClF3NO4 Cl\C(=C/C3C(C(=O)OC(c2cccc(Oc1ccccc1)c2)C(N)=O)C3(C)C)C(F)(F)F InChI=1S/C23H21ClF3NO4/c1-22(2)16(12-17(24)23(25,26)27)18(22)21(30)32-19(20(28)29)13-7-6-10-15(11-13)31-14-8-4-3-5-9-14/h3-12,16,18-19H,1-2H3,(H2,28,29)/b17-12- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (1RS,3RS)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylate 2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropane-1-carboxylate Not in list C23H21ClF3NO4 Cl\C(=C/C3C(C(=O)OC(c2cccc(Oc1ccccc1)c2)C(N)=O)C3(C)C)C(F)(F)F InChI=1S/C23H21ClF3NO4/c1-22(2)16(12-17(24)23(25,26)27)18(22)21(30)32-19(20(28)29)13-7-6-10-15(11-13)31-14-8-4-3-5-9-14/h3-12,16,18-19H,1-2H3,(H2,28,29)/b17-12- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (1RS,3RS)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylate 2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropane-1-carboxylate Not in list C23H21ClF3NO4 Cl\C(=C/C3C(C(=O)OC(c2cccc(Oc1ccccc1)c2)C(N)=O)C3(C)C)C(F)(F)F InChI=1S/C23H21ClF3NO4/c1-22(2)16(12-17(24)23(25,26)27)18(22)21(30)32-19(20(28)29)13-7-6-10-15(11-13)31-14-8-4-3-5-9-14/h3-12,16,18-19H,1-2H3,(H2,28,29)/b17-12- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (1RS,3RS)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylate 2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropane-1-carboxylate Not in list C23H21ClF3NO4 Cl\C(=C/C3C(C(=O)OC(c2cccc(Oc1ccccc1)c2)C(N)=O)C3(C)C)C(F)(F)F InChI=1S/C23H21ClF3NO4/c1-22(2)16(12-17(24)23(25,26)27)18(22)21(30)32-19(20(28)29)13-7-6-10-15(11-13)31-14-8-4-3-5-9-14/h3-12,16,18-19H,1-2H3,(H2,28,29)/b17-12- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (1RS,3RS)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylate 2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropane-1-carboxylate Not in list C23H21ClF3NO4 Cl\C(=C/C3C(C(=O)OC(c2cccc(Oc1ccccc1)c2)C(N)=O)C3(C)C)C(F)(F)F InChI=1S/C23H21ClF3NO4/c1-22(2)16(12-17(24)23(25,26)27)18(22)21(30)32-19(20(28)29)13-7-6-10-15(11-13)31-14-8-4-3-5-9-14/h3-12,16,18-19H,1-2H3,(H2,28,29)/b17-12- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (1RS,3RS)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylate 2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropane-1-carboxylate Not in list C23H21ClF3NO4 Cl\C(=C/C3C(C(=O)OC(c2cccc(Oc1ccccc1)c2)C(N)=O)C3(C)C)C(F)(F)F InChI=1S/C23H21ClF3NO4/c1-22(2)16(12-17(24)23(25,26)27)18(22)21(30)32-19(20(28)29)13-7-6-10-15(11-13)31-14-8-4-3-5-9-14/h3-12,16,18-19H,1-2H3,(H2,28,29)/b17-12- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (1RS,3RS)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylate 2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropane-1-carboxylate Not in list C23H21ClF3NO4 Cl\C(=C/C3C(C(=O)OC(c2cccc(Oc1ccccc1)c2)C(N)=O)C3(C)C)C(F)(F)F InChI=1S/C23H21ClF3NO4/c1-22(2)16(12-17(24)23(25,26)27)18(22)21(30)32-19(20(28)29)13-7-6-10-15(11-13)31-14-8-4-3-5-9-14/h3-12,16,18-19H,1-2H3,(H2,28,29)/b17-12- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (1RS,3RS)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylate 2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropane-1-carboxylate Not in list C23H21ClF3NO4 Cl\C(=C/C3C(C(=O)OC(c2cccc(Oc1ccccc1)c2)C(N)=O)C3(C)C)C(F)(F)F InChI=1S/C23H21ClF3NO4/c1-22(2)16(12-17(24)23(25,26)27)18(22)21(30)32-19(20(28)29)13-7-6-10-15(11-13)31-14-8-4-3-5-9-14/h3-12,16,18-19H,1-2H3,(H2,28,29)/b17-12- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (1RS,3RS)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylate 2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropane-1-carboxylate Not in list C23H21ClF3NO4 Cl\C(=C/C3C(C(=O)OC(c2cccc(Oc1ccccc1)c2)C(N)=O)C3(C)C)C(F)(F)F InChI=1S/C23H21ClF3NO4/c1-22(2)16(12-17(24)23(25,26)27)18(22)21(30)32-19(20(28)29)13-7-6-10-15(11-13)31-14-8-4-3-5-9-14/h3-12,16,18-19H,1-2H3,(H2,28,29)/b17-12- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (1RS,3RS)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylate 2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropane-1-carboxylate Not in list C23H21ClF3NO4 Cl\C(=C/C3C(C(=O)OC(c2cccc(Oc1ccccc1)c2)C(N)=O)C3(C)C)C(F)(F)F InChI=1S/C23H21ClF3NO4/c1-22(2)16(12-17(24)23(25,26)27)18(22)21(30)32-19(20(28)29)13-7-6-10-15(11-13)31-14-8-4-3-5-9-14/h3-12,16,18-19H,1-2H3,(H2,28,29)/b17-12- organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative no information RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (1RS,3RS)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylate 2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropane-1-carboxylate Not in list C23H21ClF3NO4 Cl\C(=C/C3C(C(=O)OC(c2cccc(Oc1ccccc1)c2)C(N)=O)C3(C)C)C(F)(F)F InChI=1S/C23H21ClF3NO4/c1-22(2)16(12-17(24)23(25,26)27)18(22)21(30)32-19(20(28)29)13-7-6-10-15(11-13)31-14-8-4-3-5-9-14/h3-12,16,18-19H,1-2H3,(H2,28,29)/b17-12- organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Negative no information RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (1RS,3RS)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylate 2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropane-1-carboxylate Not in list C23H21ClF3NO4 Cl\C(=C/C3C(C(=O)OC(c2cccc(Oc1ccccc1)c2)C(N)=O)C3(C)C)C(F)(F)F InChI=1S/C23H21ClF3NO4/c1-22(2)16(12-17(24)23(25,26)27)18(22)21(30)32-19(20(28)29)13-7-6-10-15(11-13)31-14-8-4-3-5-9-14/h3-12,16,18-19H,1-2H3,(H2,28,29)/b17-12- organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes with Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (1RS,3RS)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylate 2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropane-1-carboxylate Not in list C23H21ClF3NO4 Cl\C(=C/C3C(C(=O)OC(c2cccc(Oc1ccccc1)c2)C(N)=O)C3(C)C)C(F)(F)F InChI=1S/C23H21ClF3NO4/c1-22(2)16(12-17(24)23(25,26)27)18(22)21(30)32-19(20(28)29)13-7-6-10-15(11-13)31-14-8-4-3-5-9-14/h3-12,16,18-19H,1-2H3,(H2,28,29)/b17-12- organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes without Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (2RS)-hydroxy(3-phenoxyphenyl)acetonitrile hydroxy(3-phenoxyphenyl)acetonitrile Not in list C14H11NO2 N#CC(O)c2cc(Oc1ccccc1)ccc2 InChI=1S/C14H11NO2/c15-10-14(16)11-5-4-8-13(9-11)17-12-6-2-1-3-7-12/h1-9,14,16H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (2RS)-hydroxy(3-phenoxyphenyl)acetonitrile hydroxy(3-phenoxyphenyl)acetonitrile Not in list C14H11NO2 N#CC(O)c2cc(Oc1ccccc1)ccc2 InChI=1S/C14H11NO2/c15-10-14(16)11-5-4-8-13(9-11)17-12-6-2-1-3-7-12/h1-9,14,16H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (2RS)-hydroxy(3-phenoxyphenyl)acetonitrile hydroxy(3-phenoxyphenyl)acetonitrile Not in list C14H11NO2 N#CC(O)c2cc(Oc1ccccc1)ccc2 InChI=1S/C14H11NO2/c15-10-14(16)11-5-4-8-13(9-11)17-12-6-2-1-3-7-12/h1-9,14,16H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (2RS)-hydroxy(3-phenoxyphenyl)acetonitrile hydroxy(3-phenoxyphenyl)acetonitrile Not in list C14H11NO2 N#CC(O)c2cc(Oc1ccccc1)ccc2 InChI=1S/C14H11NO2/c15-10-14(16)11-5-4-8-13(9-11)17-12-6-2-1-3-7-12/h1-9,14,16H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (2RS)-hydroxy(3-phenoxyphenyl)acetonitrile hydroxy(3-phenoxyphenyl)acetonitrile Not in list C14H11NO2 N#CC(O)c2cc(Oc1ccccc1)ccc2 InChI=1S/C14H11NO2/c15-10-14(16)11-5-4-8-13(9-11)17-12-6-2-1-3-7-12/h1-9,14,16H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (2RS)-hydroxy(3-phenoxyphenyl)acetonitrile hydroxy(3-phenoxyphenyl)acetonitrile Not in list C14H11NO2 N#CC(O)c2cc(Oc1ccccc1)ccc2 InChI=1S/C14H11NO2/c15-10-14(16)11-5-4-8-13(9-11)17-12-6-2-1-3-7-12/h1-9,14,16H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (2RS)-hydroxy(3-phenoxyphenyl)acetonitrile hydroxy(3-phenoxyphenyl)acetonitrile Not in list C14H11NO2 N#CC(O)c2cc(Oc1ccccc1)ccc2 InChI=1S/C14H11NO2/c15-10-14(16)11-5-4-8-13(9-11)17-12-6-2-1-3-7-12/h1-9,14,16H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (2RS)-hydroxy(3-phenoxyphenyl)acetonitrile hydroxy(3-phenoxyphenyl)acetonitrile Not in list C14H11NO2 N#CC(O)c2cc(Oc1ccccc1)ccc2 InChI=1S/C14H11NO2/c15-10-14(16)11-5-4-8-13(9-11)17-12-6-2-1-3-7-12/h1-9,14,16H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (2RS)-hydroxy(3-phenoxyphenyl)acetonitrile hydroxy(3-phenoxyphenyl)acetonitrile Not in list C14H11NO2 N#CC(O)c2cc(Oc1ccccc1)ccc2 InChI=1S/C14H11NO2/c15-10-14(16)11-5-4-8-13(9-11)17-12-6-2-1-3-7-12/h1-9,14,16H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (2RS)-hydroxy(3-phenoxyphenyl)acetonitrile hydroxy(3-phenoxyphenyl)acetonitrile Not in list C14H11NO2 N#CC(O)c2cc(Oc1ccccc1)ccc2 InChI=1S/C14H11NO2/c15-10-14(16)11-5-4-8-13(9-11)17-12-6-2-1-3-7-12/h1-9,14,16H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (2RS)-hydroxy(3-phenoxyphenyl)acetonitrile hydroxy(3-phenoxyphenyl)acetonitrile Not in list C14H11NO2 N#CC(O)c2cc(Oc1ccccc1)ccc2 InChI=1S/C14H11NO2/c15-10-14(16)11-5-4-8-13(9-11)17-12-6-2-1-3-7-12/h1-9,14,16H organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (2RS)-hydroxy(3-phenoxyphenyl)acetonitrile hydroxy(3-phenoxyphenyl)acetonitrile Not in list C14H11NO2 N#CC(O)c2cc(Oc1ccccc1)ccc2 InChI=1S/C14H11NO2/c15-10-14(16)11-5-4-8-13(9-11)17-12-6-2-1-3-7-12/h1-9,14,16H organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (2RS)-hydroxy(3-phenoxyphenyl)acetonitrile hydroxy(3-phenoxyphenyl)acetonitrile Not in list C14H11NO2 N#CC(O)c2cc(Oc1ccccc1)ccc2 InChI=1S/C14H11NO2/c15-10-14(16)11-5-4-8-13(9-11)17-12-6-2-1-3-7-12/h1-9,14,16H organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (2RS)-hydroxy(3-phenoxyphenyl)acetonitrile hydroxy(3-phenoxyphenyl)acetonitrile Not in list C14H11NO2 N#CC(O)c2cc(Oc1ccccc1)ccc2 InChI=1S/C14H11NO2/c15-10-14(16)11-5-4-8-13(9-11)17-12-6-2-1-3-7-12/h1-9,14,16H organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (3-phenoxyphenyl)methanol 237-525-1 13826-35-2 (3-phenoxyphenyl)methanol Not in list C13H12O2 C1=CC=C(C=C1)OC2=CC=CC(=C2)CO InChI=1S/C13H12O2/c14-10-11-5-4-8-13(9-11)15-12-6-2-1-3-7-12/h1-9,14H,10H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (3-phenoxyphenyl)methanol 237-525-1 13826-35-2 (3-phenoxyphenyl)methanol Not in list C13H12O2 C1=CC=C(C=C1)OC2=CC=CC(=C2)CO InChI=1S/C13H12O2/c14-10-11-5-4-8-13(9-11)15-12-6-2-1-3-7-12/h1-9,14H,10H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (3-phenoxyphenyl)methanol 237-525-1 13826-35-2 (3-phenoxyphenyl)methanol Not in list C13H12O2 C1=CC=C(C=C1)OC2=CC=CC(=C2)CO InChI=1S/C13H12O2/c14-10-11-5-4-8-13(9-11)15-12-6-2-1-3-7-12/h1-9,14H,10H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (3-phenoxyphenyl)methanol 237-525-1 13826-35-2 (3-phenoxyphenyl)methanol Not in list C13H12O2 C1=CC=C(C=C1)OC2=CC=CC(=C2)CO InChI=1S/C13H12O2/c14-10-11-5-4-8-13(9-11)15-12-6-2-1-3-7-12/h1-9,14H,10H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (3-phenoxyphenyl)methanol 237-525-1 13826-35-2 (3-phenoxyphenyl)methanol Not in list C13H12O2 C1=CC=C(C=C1)OC2=CC=CC(=C2)CO InChI=1S/C13H12O2/c14-10-11-5-4-8-13(9-11)15-12-6-2-1-3-7-12/h1-9,14H,10H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (3-phenoxyphenyl)methanol 237-525-1 13826-35-2 (3-phenoxyphenyl)methanol Not in list C13H12O2 C1=CC=C(C=C1)OC2=CC=CC(=C2)CO InChI=1S/C13H12O2/c14-10-11-5-4-8-13(9-11)15-12-6-2-1-3-7-12/h1-9,14H,10H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (3-phenoxyphenyl)methanol 237-525-1 13826-35-2 (3-phenoxyphenyl)methanol Not in list C13H12O2 C1=CC=C(C=C1)OC2=CC=CC(=C2)CO InChI=1S/C13H12O2/c14-10-11-5-4-8-13(9-11)15-12-6-2-1-3-7-12/h1-9,14H,10H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (3-phenoxyphenyl)methanol 237-525-1 13826-35-2 (3-phenoxyphenyl)methanol Not in list C13H12O2 C1=CC=C(C=C1)OC2=CC=CC(=C2)CO InChI=1S/C13H12O2/c14-10-11-5-4-8-13(9-11)15-12-6-2-1-3-7-12/h1-9,14H,10H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (3-phenoxyphenyl)methanol 237-525-1 13826-35-2 (3-phenoxyphenyl)methanol Not in list C13H12O2 C1=CC=C(C=C1)OC2=CC=CC(=C2)CO InChI=1S/C13H12O2/c14-10-11-5-4-8-13(9-11)15-12-6-2-1-3-7-12/h1-9,14H,10H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (3-phenoxyphenyl)methanol 237-525-1 13826-35-2 (3-phenoxyphenyl)methanol Not in list C13H12O2 C1=CC=C(C=C1)OC2=CC=CC(=C2)CO InChI=1S/C13H12O2/c14-10-11-5-4-8-13(9-11)15-12-6-2-1-3-7-12/h1-9,14H,10H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (3-phenoxyphenyl)methanol 237-525-1 13826-35-2 (3-phenoxyphenyl)methanol Not in list C13H12O2 C1=CC=C(C=C1)OC2=CC=CC(=C2)CO InChI=1S/C13H12O2/c14-10-11-5-4-8-13(9-11)15-12-6-2-1-3-7-12/h1-9,14H,10H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (3-phenoxyphenyl)methanol 237-525-1 13826-35-2 (3-phenoxyphenyl)methanol Not in list C13H12O2 C1=CC=C(C=C1)OC2=CC=CC(=C2)CO InChI=1S/C13H12O2/c14-10-11-5-4-8-13(9-11)15-12-6-2-1-3-7-12/h1-9,14H,10H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (3-phenoxyphenyl)methanol 237-525-1 13826-35-2 (3-phenoxyphenyl)methanol Not in list C13H12O2 C1=CC=C(C=C1)OC2=CC=CC(=C2)CO InChI=1S/C13H12O2/c14-10-11-5-4-8-13(9-11)15-12-6-2-1-3-7-12/h1-9,14H,10H2 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (3-phenoxyphenyl)methanol 237-525-1 13826-35-2 (3-phenoxyphenyl)methanol Not in list C13H12O2 C1=CC=C(C=C1)OC2=CC=CC(=C2)CO InChI=1S/C13H12O2/c14-10-11-5-4-8-13(9-11)15-12-6-2-1-3-7-12/h1-9,14H,10H2 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance hydroxy(3-phenoxyphenyl)acetic acid hydroxy(3-phenoxyphenyl)acetic acid Not in list C14H12O4 O=C(O)C(O)c2cc(Oc1ccccc1)ccc2 InChI=1S/C14H12O4/c15-13(14(16)17)10-5-4-8-12(9-10)18-11-6-2-1-3-7-11/h1-9,13,15H,(H,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance hydroxy(3-phenoxyphenyl)acetic acid hydroxy(3-phenoxyphenyl)acetic acid Not in list C14H12O4 O=C(O)C(O)c2cc(Oc1ccccc1)ccc2 InChI=1S/C14H12O4/c15-13(14(16)17)10-5-4-8-12(9-10)18-11-6-2-1-3-7-11/h1-9,13,15H,(H,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance hydroxy(3-phenoxyphenyl)acetic acid hydroxy(3-phenoxyphenyl)acetic acid Not in list C14H12O4 O=C(O)C(O)c2cc(Oc1ccccc1)ccc2 InChI=1S/C14H12O4/c15-13(14(16)17)10-5-4-8-12(9-10)18-11-6-2-1-3-7-11/h1-9,13,15H,(H,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance hydroxy(3-phenoxyphenyl)acetic acid hydroxy(3-phenoxyphenyl)acetic acid Not in list C14H12O4 O=C(O)C(O)c2cc(Oc1ccccc1)ccc2 InChI=1S/C14H12O4/c15-13(14(16)17)10-5-4-8-12(9-10)18-11-6-2-1-3-7-11/h1-9,13,15H,(H,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance hydroxy(3-phenoxyphenyl)acetic acid hydroxy(3-phenoxyphenyl)acetic acid Not in list C14H12O4 O=C(O)C(O)c2cc(Oc1ccccc1)ccc2 InChI=1S/C14H12O4/c15-13(14(16)17)10-5-4-8-12(9-10)18-11-6-2-1-3-7-11/h1-9,13,15H,(H,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance hydroxy(3-phenoxyphenyl)acetic acid hydroxy(3-phenoxyphenyl)acetic acid Not in list C14H12O4 O=C(O)C(O)c2cc(Oc1ccccc1)ccc2 InChI=1S/C14H12O4/c15-13(14(16)17)10-5-4-8-12(9-10)18-11-6-2-1-3-7-11/h1-9,13,15H,(H,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance hydroxy(3-phenoxyphenyl)acetic acid hydroxy(3-phenoxyphenyl)acetic acid Not in list C14H12O4 O=C(O)C(O)c2cc(Oc1ccccc1)ccc2 InChI=1S/C14H12O4/c15-13(14(16)17)10-5-4-8-12(9-10)18-11-6-2-1-3-7-11/h1-9,13,15H,(H,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance hydroxy(3-phenoxyphenyl)acetic acid hydroxy(3-phenoxyphenyl)acetic acid Not in list C14H12O4 O=C(O)C(O)c2cc(Oc1ccccc1)ccc2 InChI=1S/C14H12O4/c15-13(14(16)17)10-5-4-8-12(9-10)18-11-6-2-1-3-7-11/h1-9,13,15H,(H,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance hydroxy(3-phenoxyphenyl)acetic acid hydroxy(3-phenoxyphenyl)acetic acid Not in list C14H12O4 O=C(O)C(O)c2cc(Oc1ccccc1)ccc2 InChI=1S/C14H12O4/c15-13(14(16)17)10-5-4-8-12(9-10)18-11-6-2-1-3-7-11/h1-9,13,15H,(H,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance hydroxy(3-phenoxyphenyl)acetic acid hydroxy(3-phenoxyphenyl)acetic acid Not in list C14H12O4 O=C(O)C(O)c2cc(Oc1ccccc1)ccc2 InChI=1S/C14H12O4/c15-13(14(16)17)10-5-4-8-12(9-10)18-11-6-2-1-3-7-11/h1-9,13,15H,(H,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance hydroxy(3-phenoxyphenyl)acetic acid hydroxy(3-phenoxyphenyl)acetic acid Not in list C14H12O4 O=C(O)C(O)c2cc(Oc1ccccc1)ccc2 InChI=1S/C14H12O4/c15-13(14(16)17)10-5-4-8-12(9-10)18-11-6-2-1-3-7-11/h1-9,13,15H,(H,16,17) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance hydroxy(3-phenoxyphenyl)acetic acid hydroxy(3-phenoxyphenyl)acetic acid Not in list C14H12O4 O=C(O)C(O)c2cc(Oc1ccccc1)ccc2 InChI=1S/C14H12O4/c15-13(14(16)17)10-5-4-8-12(9-10)18-11-6-2-1-3-7-11/h1-9,13,15H,(H,16,17) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance hydroxy(3-phenoxyphenyl)acetic acid hydroxy(3-phenoxyphenyl)acetic acid Not in list C14H12O4 O=C(O)C(O)c2cc(Oc1ccccc1)ccc2 InChI=1S/C14H12O4/c15-13(14(16)17)10-5-4-8-12(9-10)18-11-6-2-1-3-7-11/h1-9,13,15H,(H,16,17) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance hydroxy(3-phenoxyphenyl)acetic acid hydroxy(3-phenoxyphenyl)acetic acid Not in list C14H12O4 O=C(O)C(O)c2cc(Oc1ccccc1)ccc2 InChI=1S/C14H12O4/c15-13(14(16)17)10-5-4-8-12(9-10)18-11-6-2-1-3-7-11/h1-9,13,15H,(H,16,17) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid (1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid Not in list C9H10ClF3O2 Cl\C(=C/[C@H]1[C@@H](C(=O)O)C1(C)C)C(F)(F)F InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m0/s1 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female intraperitoneal 44.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid (1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid Not in list C9H10ClF3O2 Cl\C(=C/[C@@H]1[C@H](C(=O)O)C1(C)C)C(F)(F)F InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m1/s1 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female intraperitoneal 44.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid (1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid Not in list C9H10ClF3O2 Cl\C(=C/[C@@H]1[C@H](C(=O)O)C1(C)C)C(F)(F)F InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m1/s1 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female intraperitoneal 68.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Lambda-cyhalothrin 415-130-7 91465-08-6 single chemical entity Component is a metabolite of the substance (1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid (1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid Not in list C9H10ClF3O2 Cl\C(=C/[C@H]1[C@@H](C(=O)O)C1(C)C)C(F)(F)F InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m0/s1 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female intraperitoneal 68.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Sweden - CoRMS: Spain Lambda-Cyhalothrin 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin 13May2014 2014 doi:10.2903/j.efsa.2014.3677
+Pymetrozine 123312-89-0 single chemical entity Component is identical to the substance Pymetrozine 123312-89-0 6-methyl-4-[(E)-pyridin-3-ylmethylideneamino]-2,5-dihydro-1,2,4-triazin-3-one Pymetrozine C10H11N5O CC1=NNC(=O)N(C1)N=CC2=CN=CC=C2 InChI=1S/C10H11N5O/c1-8-7-15(10(16)14-13-8)12-6-9-3-2-4-11-5-9/h2-6H,7H2,1H3,(H,14,16)/b12-6+ organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is identical to the substance Pymetrozine 123312-89-0 6-methyl-4-[(E)-pyridin-3-ylmethylideneamino]-2,5-dihydro-1,2,4-triazin-3-one Pymetrozine C10H11N5O CC1=NNC(=O)N(C1)N=CC2=CN=CC=C2 InChI=1S/C10H11N5O/c1-8-7-15(10(16)14-13-8)12-6-9-3-2-4-11-5-9/h2-6H,7H2,1H3,(H,14,16)/b12-6+ organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is identical to the substance Pymetrozine 123312-89-0 6-methyl-4-[(E)-pyridin-3-ylmethylideneamino]-2,5-dihydro-1,2,4-triazin-3-one Pymetrozine C10H11N5O CC1=NNC(=O)N(C1)N=CC2=CN=CC=C2 InChI=1S/C10H11N5O/c1-8-7-15(10(16)14-13-8)12-6-9-3-2-4-11-5-9/h2-6H,7H2,1H3,(H,14,16)/b12-6+ organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is identical to the substance Pymetrozine 123312-89-0 6-methyl-4-[(E)-pyridin-3-ylmethylideneamino]-2,5-dihydro-1,2,4-triazin-3-one Pymetrozine C10H11N5O CC1=NNC(=O)N(C1)N=CC2=CN=CC=C2 InChI=1S/C10H11N5O/c1-8-7-15(10(16)14-13-8)12-6-9-3-2-4-11-5-9/h2-6H,7H2,1H3,(H,14,16)/b12-6+ organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is identical to the substance Pymetrozine 123312-89-0 6-methyl-4-[(E)-pyridin-3-ylmethylideneamino]-2,5-dihydro-1,2,4-triazin-3-one Pymetrozine C10H11N5O CC1=NNC(=O)N(C1)N=CC2=CN=CC=C2 InChI=1S/C10H11N5O/c1-8-7-15(10(16)14-13-8)12-6-9-3-2-4-11-5-9/h2-6H,7H2,1H3,(H,14,16)/b12-6+ organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is identical to the substance Pymetrozine 123312-89-0 6-methyl-4-[(E)-pyridin-3-ylmethylideneamino]-2,5-dihydro-1,2,4-triazin-3-one Pymetrozine C10H11N5O CC1=NNC(=O)N(C1)N=CC2=CN=CC=C2 InChI=1S/C10H11N5O/c1-8-7-15(10(16)14-13-8)12-6-9-3-2-4-11-5-9/h2-6H,7H2,1H3,(H,14,16)/b12-6+ organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is identical to the substance Pymetrozine 123312-89-0 6-methyl-4-[(E)-pyridin-3-ylmethylideneamino]-2,5-dihydro-1,2,4-triazin-3-one Pymetrozine C10H11N5O CC1=NNC(=O)N(C1)N=CC2=CN=CC=C2 InChI=1S/C10H11N5O/c1-8-7-15(10(16)14-13-8)12-6-9-3-2-4-11-5-9/h2-6H,7H2,1H3,(H,14,16)/b12-6+ organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is identical to the substance Pymetrozine 123312-89-0 6-methyl-4-[(E)-pyridin-3-ylmethylideneamino]-2,5-dihydro-1,2,4-triazin-3-one Pymetrozine C10H11N5O CC1=NNC(=O)N(C1)N=CC2=CN=CC=C2 InChI=1S/C10H11N5O/c1-8-7-15(10(16)14-13-8)12-6-9-3-2-4-11-5-9/h2-6H,7H2,1H3,(H,14,16)/b12-6+ organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is identical to the substance Pymetrozine 123312-89-0 6-methyl-4-[(E)-pyridin-3-ylmethylideneamino]-2,5-dihydro-1,2,4-triazin-3-one Pymetrozine C10H11N5O CC1=NNC(=O)N(C1)N=CC2=CN=CC=C2 InChI=1S/C10H11N5O/c1-8-7-15(10(16)14-13-8)12-6-9-3-2-4-11-5-9/h2-6H,7H2,1H3,(H,14,16)/b12-6+ organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is identical to the substance Pymetrozine 123312-89-0 6-methyl-4-[(E)-pyridin-3-ylmethylideneamino]-2,5-dihydro-1,2,4-triazin-3-one Pymetrozine C10H11N5O CC1=NNC(=O)N(C1)N=CC2=CN=CC=C2 InChI=1S/C10H11N5O/c1-8-7-15(10(16)14-13-8)12-6-9-3-2-4-11-5-9/h2-6H,7H2,1H3,(H,14,16)/b12-6+ organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is identical to the substance Pymetrozine 123312-89-0 6-methyl-4-[(E)-pyridin-3-ylmethylideneamino]-2,5-dihydro-1,2,4-triazin-3-one Pymetrozine C10H11N5O CC1=NNC(=O)N(C1)N=CC2=CN=CC=C2 InChI=1S/C10H11N5O/c1-8-7-15(10(16)14-13-8)12-6-9-3-2-4-11-5-9/h2-6H,7H2,1H3,(H,14,16)/b12-6+ organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is identical to the substance Pymetrozine 123312-89-0 6-methyl-4-[(E)-pyridin-3-ylmethylideneamino]-2,5-dihydro-1,2,4-triazin-3-one Pymetrozine C10H11N5O CC1=NNC(=O)N(C1)N=CC2=CN=CC=C2 InChI=1S/C10H11N5O/c1-8-7-15(10(16)14-13-8)12-6-9-3-2-4-11-5-9/h2-6H,7H2,1H3,(H,14,16)/b12-6+ organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is identical to the substance Pymetrozine 123312-89-0 6-methyl-4-[(E)-pyridin-3-ylmethylideneamino]-2,5-dihydro-1,2,4-triazin-3-one Pymetrozine C10H11N5O CC1=NNC(=O)N(C1)N=CC2=CN=CC=C2 InChI=1S/C10H11N5O/c1-8-7-15(10(16)14-13-8)12-6-9-3-2-4-11-5-9/h2-6H,7H2,1H3,(H,14,16)/b12-6+ organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is identical to the substance Pymetrozine 123312-89-0 6-methyl-4-[(E)-pyridin-3-ylmethylideneamino]-2,5-dihydro-1,2,4-triazin-3-one Pymetrozine C10H11N5O CC1=NNC(=O)N(C1)N=CC2=CN=CC=C2 InChI=1S/C10H11N5O/c1-8-7-15(10(16)14-13-8)12-6-9-3-2-4-11-5-9/h2-6H,7H2,1H3,(H,14,16)/b12-6+ organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is identical to the substance Pymetrozine 123312-89-0 6-methyl-4-[(E)-pyridin-3-ylmethylideneamino]-2,5-dihydro-1,2,4-triazin-3-one Pymetrozine C10H11N5O CC1=NNC(=O)N(C1)N=CC2=CN=CC=C2 InChI=1S/C10H11N5O/c1-8-7-15(10(16)14-13-8)12-6-9-3-2-4-11-5-9/h2-6H,7H2,1H3,(H,14,16)/b12-6+ organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is identical to the substance Pymetrozine 123312-89-0 6-methyl-4-[(E)-pyridin-3-ylmethylideneamino]-2,5-dihydro-1,2,4-triazin-3-one Pymetrozine C10H11N5O CC1=NNC(=O)N(C1)N=CC2=CN=CC=C2 InChI=1S/C10H11N5O/c1-8-7-15(10(16)14-13-8)12-6-9-3-2-4-11-5-9/h2-6H,7H2,1H3,(H,14,16)/b12-6+ organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Tif:MAGf(SPF) 16 Male/Female oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is identical to the substance Pymetrozine 123312-89-0 6-methyl-4-[(E)-pyridin-3-ylmethylideneamino]-2,5-dihydro-1,2,4-triazin-3-one Pymetrozine C10H11N5O CC1=NNC(=O)N(C1)N=CC2=CN=CC=C2 InChI=1S/C10H11N5O/c1-8-7-15(10(16)14-13-8)12-6-9-3-2-4-11-5-9/h2-6H,7H2,1H3,(H,14,16)/b12-6+ organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Tif:MAGf(SPF) 16 Male/Female oral: unspecified 16.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is identical to the substance Pymetrozine 123312-89-0 6-methyl-4-[(E)-pyridin-3-ylmethylideneamino]-2,5-dihydro-1,2,4-triazin-3-one Pymetrozine C10H11N5O CC1=NNC(=O)N(C1)N=CC2=CN=CC=C2 InChI=1S/C10H11N5O/c1-8-7-15(10(16)14-13-8)12-6-9-3-2-4-11-5-9/h2-6H,7H2,1H3,(H,14,16)/b12-6+ organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Tif:MAGf(SPF) 16 Male/Female oral: unspecified 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is identical to the substance Pymetrozine 123312-89-0 6-methyl-4-[(E)-pyridin-3-ylmethylideneamino]-2,5-dihydro-1,2,4-triazin-3-one Pymetrozine C10H11N5O CC1=NNC(=O)N(C1)N=CC2=CN=CC=C2 InChI=1S/C10H11N5O/c1-8-7-15(10(16)14-13-8)12-6-9-3-2-4-11-5-9/h2-6H,7H2,1H3,(H,14,16)/b12-6+ organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Tif:MAGf(SPF) 16 Male/Female oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is identical to the substance Pymetrozine 123312-89-0 6-methyl-4-[(E)-pyridin-3-ylmethylideneamino]-2,5-dihydro-1,2,4-triazin-3-one Pymetrozine C10H11N5O CC1=NNC(=O)N(C1)N=CC2=CN=CC=C2 InChI=1S/C10H11N5O/c1-8-7-15(10(16)14-13-8)12-6-9-3-2-4-11-5-9/h2-6H,7H2,1H3,(H,14,16)/b12-6+ organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Tif:MAGf(SPF) 10 Male/Female oral: unspecified 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is identical to the substance Pymetrozine 123312-89-0 6-methyl-4-[(E)-pyridin-3-ylmethylideneamino]-2,5-dihydro-1,2,4-triazin-3-one Pymetrozine C10H11N5O CC1=NNC(=O)N(C1)N=CC2=CN=CC=C2 InChI=1S/C10H11N5O/c1-8-7-15(10(16)14-13-8)12-6-9-3-2-4-11-5-9/h2-6H,7H2,1H3,(H,14,16)/b12-6+ organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Tif:MAGf(SPF) 10 Male/Female oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is identical to the substance Pymetrozine 123312-89-0 6-methyl-4-[(E)-pyridin-3-ylmethylideneamino]-2,5-dihydro-1,2,4-triazin-3-one Pymetrozine C10H11N5O CC1=NNC(=O)N(C1)N=CC2=CN=CC=C2 InChI=1S/C10H11N5O/c1-8-7-15(10(16)14-13-8)12-6-9-3-2-4-11-5-9/h2-6H,7H2,1H3,(H,14,16)/b12-6+ organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable House mouse (as animal) B6C3F1 3 Male oral: unspecified 16.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is identical to the substance Pymetrozine 123312-89-0 6-methyl-4-[(E)-pyridin-3-ylmethylideneamino]-2,5-dihydro-1,2,4-triazin-3-one Pymetrozine C10H11N5O CC1=NNC(=O)N(C1)N=CC2=CN=CC=C2 InChI=1S/C10H11N5O/c1-8-7-15(10(16)14-13-8)12-6-9-3-2-4-11-5-9/h2-6H,7H2,1H3,(H,14,16)/b12-6+ organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable House mouse (as animal) B6C3F1 3 Male oral: unspecified 2.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is a metabolite of the substance 4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one 4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one Not in list C4H8N4O O=C1NN=C(C)CN1N InChI=1S/C4H8N4O/c1-3-2-8(5)4(9)7-6-3/h2,5H2,1H3,(H,7,9) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is a metabolite of the substance 4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one 4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one Not in list C4H8N4O O=C1NN=C(C)CN1N InChI=1S/C4H8N4O/c1-3-2-8(5)4(9)7-6-3/h2,5H2,1H3,(H,7,9) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Positive RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is a metabolite of the substance 4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one 4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one Not in list C4H8N4O O=C1NN=C(C)CN1N InChI=1S/C4H8N4O/c1-3-2-8(5)4(9)7-6-3/h2,5H2,1H3,(H,7,9) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Positive RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is a metabolite of the substance 4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one 4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one Not in list C4H8N4O O=C1NN=C(C)CN1N InChI=1S/C4H8N4O/c1-3-2-8(5)4(9)7-6-3/h2,5H2,1H3,(H,7,9) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes without Negative RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is a metabolite of the substance 4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one 4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one Not in list C4H8N4O O=C1NN=C(C)CN1N InChI=1S/C4H8N4O/c1-3-2-8(5)4(9)7-6-3/h2,5H2,1H3,(H,7,9) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes with Negative RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is a metabolite of the substance 4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one 4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one Not in list C4H8N4O O=C1NN=C(C)CN1N InChI=1S/C4H8N4O/c1-3-2-8(5)4(9)7-6-3/h2,5H2,1H3,(H,7,9) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is a metabolite of the substance 4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one 4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one Not in list C4H8N4O O=C1NN=C(C)CN1N InChI=1S/C4H8N4O/c1-3-2-8(5)4(9)7-6-3/h2,5H2,1H3,(H,7,9) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is a metabolite of the substance 4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one 4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one Not in list C4H8N4O O=C1NN=C(C)CN1N InChI=1S/C4H8N4O/c1-3-2-8(5)4(9)7-6-3/h2,5H2,1H3,(H,7,9) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is a metabolite of the substance 4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one 4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one Not in list C4H8N4O O=C1NN=C(C)CN1N InChI=1S/C4H8N4O/c1-3-2-8(5)4(9)7-6-3/h2,5H2,1H3,(H,7,9) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is a metabolite of the substance 4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one 4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one Not in list C4H8N4O O=C1NN=C(C)CN1N InChI=1S/C4H8N4O/c1-3-2-8(5)4(9)7-6-3/h2,5H2,1H3,(H,7,9) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Positive RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is a metabolite of the substance 4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one 4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one Not in list C4H8N4O O=C1NN=C(C)CN1N InChI=1S/C4H8N4O/c1-3-2-8(5)4(9)7-6-3/h2,5H2,1H3,(H,7,9) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Positive RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is a metabolite of the substance 4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one 4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one Not in list C4H8N4O O=C1NN=C(C)CN1N InChI=1S/C4H8N4O/c1-3-2-8(5)4(9)7-6-3/h2,5H2,1H3,(H,7,9) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is a metabolite of the substance 4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one 4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one Not in list C4H8N4O O=C1NN=C(C)CN1N InChI=1S/C4H8N4O/c1-3-2-8(5)4(9)7-6-3/h2,5H2,1H3,(H,7,9) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is a metabolite of the substance 4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one 4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one Not in list C4H8N4O O=C1NN=C(C)CN1N InChI=1S/C4H8N4O/c1-3-2-8(5)4(9)7-6-3/h2,5H2,1H3,(H,7,9) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is a metabolite of the substance 4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one 4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one Not in list C4H8N4O O=C1NN=C(C)CN1N InChI=1S/C4H8N4O/c1-3-2-8(5)4(9)7-6-3/h2,5H2,1H3,(H,7,9) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is a metabolite of the substance 4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one 4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one Not in list C4H8N4O O=C1NN=C(C)CN1N InChI=1S/C4H8N4O/c1-3-2-8(5)4(9)7-6-3/h2,5H2,1H3,(H,7,9) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is a metabolite of the substance 4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one 4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one Not in list C4H8N4O O=C1NN=C(C)CN1N InChI=1S/C4H8N4O/c1-3-2-8(5)4(9)7-6-3/h2,5H2,1H3,(H,7,9) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is a metabolite of the substance 4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one 4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one Not in list C4H8N4O O=C1NN=C(C)CN1N InChI=1S/C4H8N4O/c1-3-2-8(5)4(9)7-6-3/h2,5H2,1H3,(H,7,9) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is a metabolite of the substance 4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one 4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one Not in list C4H8N4O O=C1NN=C(C)CN1N InChI=1S/C4H8N4O/c1-3-2-8(5)4(9)7-6-3/h2,5H2,1H3,(H,7,9) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is a metabolite of the substance 4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one 4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one Not in list C4H8N4O O=C1NN=C(C)CN1N InChI=1S/C4H8N4O/c1-3-2-8(5)4(9)7-6-3/h2,5H2,1H3,(H,7,9) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is a metabolite of the substance 4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one 4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one Not in list C4H8N4O O=C1NN=C(C)CN1N InChI=1S/C4H8N4O/c1-3-2-8(5)4(9)7-6-3/h2,5H2,1H3,(H,7,9) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is a metabolite of the substance 4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one 4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one Not in list C4H8N4O O=C1NN=C(C)CN1N InChI=1S/C4H8N4O/c1-3-2-8(5)4(9)7-6-3/h2,5H2,1H3,(H,7,9) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is a metabolite of the substance 4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one 4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one Not in list C4H8N4O O=C1NN=C(C)CN1N InChI=1S/C4H8N4O/c1-3-2-8(5)4(9)7-6-3/h2,5H2,1H3,(H,7,9) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is a metabolite of the substance 4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one 4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one Not in list C4H8N4O O=C1NN=C(C)CN1N InChI=1S/C4H8N4O/c1-3-2-8(5)4(9)7-6-3/h2,5H2,1H3,(H,7,9) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is a metabolite of the substance nicotinaldehyde 207-900-4 pyridine-3-carbaldehyde Not in list C6H5NO C1=CC(=CN=C1)C=O InChI=1S/C6H5NO/c8-5-6-2-1-3-7-4-6/h1-5H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is a metabolite of the substance nicotinaldehyde 207-900-4 pyridine-3-carbaldehyde Not in list C6H5NO C1=CC(=CN=C1)C=O InChI=1S/C6H5NO/c8-5-6-2-1-3-7-4-6/h1-5H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is a metabolite of the substance nicotinaldehyde 207-900-4 pyridine-3-carbaldehyde Not in list C6H5NO C1=CC(=CN=C1)C=O InChI=1S/C6H5NO/c8-5-6-2-1-3-7-4-6/h1-5H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is a metabolite of the substance nicotinaldehyde 207-900-4 pyridine-3-carbaldehyde Not in list C6H5NO C1=CC(=CN=C1)C=O InChI=1S/C6H5NO/c8-5-6-2-1-3-7-4-6/h1-5H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is a metabolite of the substance nicotinaldehyde 207-900-4 pyridine-3-carbaldehyde Not in list C6H5NO C1=CC(=CN=C1)C=O InChI=1S/C6H5NO/c8-5-6-2-1-3-7-4-6/h1-5H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is a metabolite of the substance nicotinaldehyde 207-900-4 pyridine-3-carbaldehyde Not in list C6H5NO C1=CC(=CN=C1)C=O InChI=1S/C6H5NO/c8-5-6-2-1-3-7-4-6/h1-5H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is a metabolite of the substance nicotinaldehyde 207-900-4 pyridine-3-carbaldehyde Not in list C6H5NO C1=CC(=CN=C1)C=O InChI=1S/C6H5NO/c8-5-6-2-1-3-7-4-6/h1-5H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is a metabolite of the substance nicotinaldehyde 207-900-4 pyridine-3-carbaldehyde Not in list C6H5NO C1=CC(=CN=C1)C=O InChI=1S/C6H5NO/c8-5-6-2-1-3-7-4-6/h1-5H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is a metabolite of the substance nicotinaldehyde 207-900-4 pyridine-3-carbaldehyde Not in list C6H5NO C1=CC(=CN=C1)C=O InChI=1S/C6H5NO/c8-5-6-2-1-3-7-4-6/h1-5H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is a metabolite of the substance nicotinaldehyde 207-900-4 pyridine-3-carbaldehyde Not in list C6H5NO C1=CC(=CN=C1)C=O InChI=1S/C6H5NO/c8-5-6-2-1-3-7-4-6/h1-5H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is a metabolite of the substance nicotinaldehyde 207-900-4 pyridine-3-carbaldehyde Not in list C6H5NO C1=CC(=CN=C1)C=O InChI=1S/C6H5NO/c8-5-6-2-1-3-7-4-6/h1-5H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Positive RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is a metabolite of the substance nicotinaldehyde 207-900-4 pyridine-3-carbaldehyde Not in list C6H5NO C1=CC(=CN=C1)C=O InChI=1S/C6H5NO/c8-5-6-2-1-3-7-4-6/h1-5H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Positive RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is a metabolite of the substance nicotinaldehyde 207-900-4 pyridine-3-carbaldehyde Not in list C6H5NO C1=CC(=CN=C1)C=O InChI=1S/C6H5NO/c8-5-6-2-1-3-7-4-6/h1-5H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Positive RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is a metabolite of the substance nicotinaldehyde 207-900-4 pyridine-3-carbaldehyde Not in list C6H5NO C1=CC(=CN=C1)C=O InChI=1S/C6H5NO/c8-5-6-2-1-3-7-4-6/h1-5H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Positive RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is a metabolite of the substance nicotinaldehyde 207-900-4 pyridine-3-carbaldehyde Not in list C6H5NO C1=CC(=CN=C1)C=O InChI=1S/C6H5NO/c8-5-6-2-1-3-7-4-6/h1-5H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo Equivalent or similar to OECD Guideline 489 Yes Acceptable House mouse (as animal) B6C3F1 4 Male oral: unspecified 16.0000000000 h yes, concurrent vehicle not applicable Positive RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is a metabolite of the substance nicotinaldehyde 207-900-4 pyridine-3-carbaldehyde Not in list C6H5NO C1=CC(=CN=C1)C=O InChI=1S/C6H5NO/c8-5-6-2-1-3-7-4-6/h1-5H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo Equivalent or similar to OECD Guideline 489 Yes Acceptable House mouse (as animal) B6C3F1 4 Male oral: unspecified 2.0000000000 h yes, concurrent vehicle not applicable Positive RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is a metabolite of the substance nicotinaldehyde 207-900-4 pyridine-3-carbaldehyde Not in list C6H5NO C1=CC(=CN=C1)C=O InChI=1S/C6H5NO/c8-5-6-2-1-3-7-4-6/h1-5H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable House mouse (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is a metabolite of the substance nicotinaldehyde 207-900-4 pyridine-3-carbaldehyde Not in list C6H5NO C1=CC(=CN=C1)C=O InChI=1S/C6H5NO/c8-5-6-2-1-3-7-4-6/h1-5H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vitro No guideline available Not reported Not applicable Acceptable House mouse (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is a metabolite of the substance nicotinaldehyde 207-900-4 pyridine-3-carbaldehyde Not in list C6H5NO C1=CC(=CN=C1)C=O InChI=1S/C6H5NO/c8-5-6-2-1-3-7-4-6/h1-5H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) B6C3F1 5 Male oral: unspecified 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Pymetrozine 123312-89-0 single chemical entity Component is a metabolite of the substance nicotinaldehyde 207-900-4 pyridine-3-carbaldehyde Not in list C6H5NO C1=CC(=CN=C1)C=O InChI=1S/C6H5NO/c8-5-6-2-1-3-7-4-6/h1-5H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) B6C3F1 5 Male oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Germany - CoRMS: Belgium Pymetrozine (Final Addendum to the DAR) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine 09Sep2014 2014 doi:10.2903/j.efsa.2014.3817
+Propaquizafop 111479-05-1 single chemical entity Component is identical to the substance Propaquizafop 111479-05-1 2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate Propaquizafop C22H22ClN3O5 C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2 InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Italy Propaquizafop 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P) 17Mar2009 2009 doi:10.2903/j.efsa.2009.204r
+Propaquizafop 111479-05-1 single chemical entity Component is identical to the substance Propaquizafop 111479-05-1 2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate Propaquizafop C22H22ClN3O5 C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2 InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes with Negative RMS: Italy Propaquizafop 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P) 17Mar2009 2009 doi:10.2903/j.efsa.2009.204r
+Propaquizafop 111479-05-1 single chemical entity Component is identical to the substance Propaquizafop 111479-05-1 2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate Propaquizafop C22H22ClN3O5 C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2 InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes with Negative RMS: Italy Propaquizafop 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P) 17Mar2009 2009 doi:10.2903/j.efsa.2009.204r
+Propaquizafop 111479-05-1 single chemical entity Component is identical to the substance Propaquizafop 111479-05-1 2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate Propaquizafop C22H22ClN3O5 C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2 InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes without Negative RMS: Italy Propaquizafop 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P) 17Mar2009 2009 doi:10.2903/j.efsa.2009.204r
+Propaquizafop 111479-05-1 single chemical entity Component is identical to the substance Propaquizafop 111479-05-1 2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate Propaquizafop C22H22ClN3O5 C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2 InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: Italy Propaquizafop 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P) 17Mar2009 2009 doi:10.2903/j.efsa.2009.204r
+Propaquizafop 111479-05-1 single chemical entity Component is identical to the substance Propaquizafop 111479-05-1 2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate Propaquizafop C22H22ClN3O5 C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2 InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Italy Propaquizafop 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P) 17Mar2009 2009 doi:10.2903/j.efsa.2009.204r
+Propaquizafop 111479-05-1 single chemical entity Component is identical to the substance Propaquizafop 111479-05-1 2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate Propaquizafop C22H22ClN3O5 C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2 InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Italy Propaquizafop 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P) 17Mar2009 2009 doi:10.2903/j.efsa.2009.204r
+Propaquizafop 111479-05-1 single chemical entity Component is identical to the substance Propaquizafop 111479-05-1 2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate Propaquizafop C22H22ClN3O5 C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2 InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Italy Propaquizafop 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P) 17Mar2009 2009 doi:10.2903/j.efsa.2009.204r
+Propaquizafop 111479-05-1 single chemical entity Component is identical to the substance Propaquizafop 111479-05-1 2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate Propaquizafop C22H22ClN3O5 C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2 InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Italy Propaquizafop 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P) 17Mar2009 2009 doi:10.2903/j.efsa.2009.204r
+Propaquizafop 111479-05-1 single chemical entity Component is identical to the substance Propaquizafop 111479-05-1 2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate Propaquizafop C22H22ClN3O5 C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2 InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Italy Propaquizafop 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P) 17Mar2009 2009 doi:10.2903/j.efsa.2009.204r
+Propaquizafop 111479-05-1 single chemical entity Component is identical to the substance Propaquizafop 111479-05-1 2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate Propaquizafop C22H22ClN3O5 C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2 InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Italy Propaquizafop 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P) 17Mar2009 2009 doi:10.2903/j.efsa.2009.204r
+Propaquizafop 111479-05-1 single chemical entity Component is identical to the substance Propaquizafop 111479-05-1 2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate Propaquizafop C22H22ClN3O5 C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2 InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Italy Propaquizafop 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P) 17Mar2009 2009 doi:10.2903/j.efsa.2009.204r
+Propaquizafop 111479-05-1 single chemical entity Component is identical to the substance Propaquizafop 111479-05-1 2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate Propaquizafop C22H22ClN3O5 C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2 InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: Italy Propaquizafop 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P) 17Mar2009 2009 doi:10.2903/j.efsa.2009.204r
+Propaquizafop 111479-05-1 single chemical entity Component is identical to the substance Propaquizafop 111479-05-1 2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate Propaquizafop C22H22ClN3O5 C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2 InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes without Negative RMS: Italy Propaquizafop 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P) 17Mar2009 2009 doi:10.2903/j.efsa.2009.204r
+Propaquizafop 111479-05-1 single chemical entity Component is identical to the substance Propaquizafop 111479-05-1 2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate Propaquizafop C22H22ClN3O5 C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2 InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: Italy Propaquizafop 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P) 17Mar2009 2009 doi:10.2903/j.efsa.2009.204r
+Propaquizafop 111479-05-1 single chemical entity Component is identical to the substance Propaquizafop 111479-05-1 2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate Propaquizafop C22H22ClN3O5 C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2 InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: Italy Propaquizafop 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P) 17Mar2009 2009 doi:10.2903/j.efsa.2009.204r
+Propaquizafop 111479-05-1 single chemical entity Component is identical to the substance Propaquizafop 111479-05-1 2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate Propaquizafop C22H22ClN3O5 C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2 InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Italy Propaquizafop 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P) 17Mar2009 2009 doi:10.2903/j.efsa.2009.204r
+Propaquizafop 111479-05-1 single chemical entity Component is identical to the substance Propaquizafop 111479-05-1 2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate Propaquizafop C22H22ClN3O5 C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2 InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Italy Propaquizafop 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P) 17Mar2009 2009 doi:10.2903/j.efsa.2009.204r
+Propaquizafop 111479-05-1 single chemical entity Component is identical to the substance Propaquizafop 111479-05-1 2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate Propaquizafop C22H22ClN3O5 C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2 InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Italy Propaquizafop 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P) 17Mar2009 2009 doi:10.2903/j.efsa.2009.204r
+Propaquizafop 111479-05-1 single chemical entity Component is identical to the substance Propaquizafop 111479-05-1 2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate Propaquizafop C22H22ClN3O5 C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2 InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Italy Propaquizafop 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P) 17Mar2009 2009 doi:10.2903/j.efsa.2009.204r
+Propaquizafop 111479-05-1 single chemical entity Component is identical to the substance Propaquizafop 111479-05-1 2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate Propaquizafop C22H22ClN3O5 C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2 InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes without Negative RMS: Italy Propaquizafop 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P) 17Mar2009 2009 doi:10.2903/j.efsa.2009.204r
+Propaquizafop 111479-05-1 single chemical entity Component is identical to the substance Propaquizafop 111479-05-1 2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate Propaquizafop C22H22ClN3O5 C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2 InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes with Negative RMS: Italy Propaquizafop 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P) 17Mar2009 2009 doi:10.2903/j.efsa.2009.204r
+Propaquizafop 111479-05-1 single chemical entity Component is identical to the substance Propaquizafop 111479-05-1 2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate Propaquizafop C22H22ClN3O5 C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2 InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Italy Propaquizafop 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P) 17Mar2009 2009 doi:10.2903/j.efsa.2009.204r
+Propaquizafop 111479-05-1 single chemical entity Component is identical to the substance Propaquizafop 111479-05-1 2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate Propaquizafop C22H22ClN3O5 C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2 InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Italy Propaquizafop 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P) 17Mar2009 2009 doi:10.2903/j.efsa.2009.204r
+Propaquizafop 111479-05-1 single chemical entity Component is identical to the substance Propaquizafop 111479-05-1 2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate Propaquizafop C22H22ClN3O5 C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2 InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Italy Propaquizafop 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P) 17Mar2009 2009 doi:10.2903/j.efsa.2009.204r
+Propaquizafop 111479-05-1 single chemical entity Component is identical to the substance Propaquizafop 111479-05-1 2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate Propaquizafop C22H22ClN3O5 C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2 InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Italy Propaquizafop 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P) 17Mar2009 2009 doi:10.2903/j.efsa.2009.204r
+Propaquizafop 111479-05-1 single chemical entity Component is identical to the substance Propaquizafop 111479-05-1 2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate Propaquizafop C22H22ClN3O5 C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2 InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes without Negative RMS: Italy Propaquizafop 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P) 17Mar2009 2009 doi:10.2903/j.efsa.2009.204r
+Propaquizafop 111479-05-1 single chemical entity Component is identical to the substance Propaquizafop 111479-05-1 2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate Propaquizafop C22H22ClN3O5 C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2 InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes with Negative RMS: Italy Propaquizafop 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P) 17Mar2009 2009 doi:10.2903/j.efsa.2009.204r
+Propaquizafop 111479-05-1 single chemical entity Component is identical to the substance Propaquizafop 111479-05-1 2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate Propaquizafop C22H22ClN3O5 C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2 InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: Italy Propaquizafop 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P) 17Mar2009 2009 doi:10.2903/j.efsa.2009.204r
+Propaquizafop 111479-05-1 single chemical entity Component is identical to the substance Propaquizafop 111479-05-1 2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate Propaquizafop C22H22ClN3O5 C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2 InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Negative RMS: Italy Propaquizafop 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P) 17Mar2009 2009 doi:10.2903/j.efsa.2009.204r
+Propaquizafop 111479-05-1 single chemical entity Component is identical to the substance Propaquizafop 111479-05-1 2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate Propaquizafop C22H22ClN3O5 C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2 InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1 organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No data Acceptable Rat (as animal) hepatocytes Not reported yes without Negative RMS: Italy Propaquizafop 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P) 17Mar2009 2009 doi:10.2903/j.efsa.2009.204r
+Propaquizafop 111479-05-1 single chemical entity Component is identical to the substance Propaquizafop 111479-05-1 2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate Propaquizafop C22H22ClN3O5 C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2 InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No data Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Positive RMS: Italy Propaquizafop 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P) 17Mar2009 2009 doi:10.2903/j.efsa.2009.204r
+Propaquizafop 111479-05-1 single chemical entity Component is identical to the substance Propaquizafop 111479-05-1 2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate Propaquizafop C22H22ClN3O5 C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2 InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No data Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Italy Propaquizafop 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P) 17Mar2009 2009 doi:10.2903/j.efsa.2009.204r
+Propaquizafop 111479-05-1 single chemical entity Component is identical to the substance Propaquizafop 111479-05-1 2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate Propaquizafop C22H22ClN3O5 C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2 InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No data Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Italy Propaquizafop 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P) 17Mar2009 2009 doi:10.2903/j.efsa.2009.204r
+Propaquizafop 111479-05-1 single chemical entity Component is identical to the substance Propaquizafop 111479-05-1 2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate Propaquizafop C22H22ClN3O5 C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2 InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No data Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Italy Propaquizafop 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P) 17Mar2009 2009 doi:10.2903/j.efsa.2009.204r
+Propaquizafop 111479-05-1 single chemical entity Component is identical to the substance Propaquizafop 111479-05-1 2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate Propaquizafop C22H22ClN3O5 C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2 InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1 organic compound Other Other genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro Equivalent or similar to OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay) No data Acceptable Saccharomyces cerevisiae (as organism) D7 Not reported yes without Negative RMS: Italy Propaquizafop 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P) 17Mar2009 2009 doi:10.2903/j.efsa.2009.204r
+Propaquizafop 111479-05-1 single chemical entity Component is identical to the substance Propaquizafop 111479-05-1 2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate Propaquizafop C22H22ClN3O5 C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2 InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1 organic compound Other Other genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro Equivalent or similar to OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay) No data Acceptable Saccharomyces cerevisiae (as organism) D7 Not reported yes with Negative RMS: Italy Propaquizafop 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P) 17Mar2009 2009 doi:10.2903/j.efsa.2009.204r
+Propaquizafop 111479-05-1 single chemical entity Component is identical to the substance Propaquizafop 111479-05-1 2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate Propaquizafop C22H22ClN3O5 C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2 InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Not reported 12 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Positive indirect evidence-systemic toxicity RMS: Italy Propaquizafop 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P) 17Mar2009 2009 doi:10.2903/j.efsa.2009.204r
+Propaquizafop 111479-05-1 single chemical entity Component is identical to the substance Propaquizafop 111479-05-1 2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate Propaquizafop C22H22ClN3O5 C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2 InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Positive indirect evidence-systemic toxicity RMS: Italy Propaquizafop 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P) 17Mar2009 2009 doi:10.2903/j.efsa.2009.204r
+Propaquizafop 111479-05-1 single chemical entity Component is identical to the substance Propaquizafop 111479-05-1 2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate Propaquizafop C22H22ClN3O5 C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2 InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Positive indirect evidence-systemic toxicity RMS: Italy Propaquizafop 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P) 17Mar2009 2009 doi:10.2903/j.efsa.2009.204r
+Propaquizafop 111479-05-1 single chemical entity Component is identical to the substance Propaquizafop 111479-05-1 2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate Propaquizafop C22H22ClN3O5 C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2 InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 72.0000000000 h yes, concurrent vehicle not applicable Positive indirect evidence-systemic toxicity RMS: Italy Propaquizafop 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P) 17Mar2009 2009 doi:10.2903/j.efsa.2009.204r
+Propaquizafop 111479-05-1 single chemical entity Component is identical to the substance Propaquizafop 111479-05-1 2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate Propaquizafop C22H22ClN3O5 C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2 InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Not reported 12 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Italy Propaquizafop 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P) 17Mar2009 2009 doi:10.2903/j.efsa.2009.204r
+Propaquizafop 111479-05-1 single chemical entity Component is identical to the substance Propaquizafop 111479-05-1 2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate Propaquizafop C22H22ClN3O5 C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2 InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Not reported 12 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Positive no evidence RMS: Italy Propaquizafop 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P) 17Mar2009 2009 doi:10.2903/j.efsa.2009.204r
+Propaquizafop 111479-05-1 single chemical entity Component is identical to the substance Propaquizafop 111479-05-1 2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate Propaquizafop C22H22ClN3O5 C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2 InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Not reported 10 Male/Female oral: unspecified 72.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity$indirect evidence-systemic toxicity RMS: Italy Propaquizafop 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P) 17Mar2009 2009 doi:10.2903/j.efsa.2009.204r
+Propaquizafop 111479-05-1 single chemical entity Component is identical to the substance Propaquizafop 111479-05-1 2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate Propaquizafop C22H22ClN3O5 C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2 InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Not reported 10 Male/Female oral: unspecified 48.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity$indirect evidence-systemic toxicity RMS: Italy Propaquizafop 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P) 17Mar2009 2009 doi:10.2903/j.efsa.2009.204r
+Propaquizafop 111479-05-1 single chemical entity Component is identical to the substance Propaquizafop 111479-05-1 2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate Propaquizafop C22H22ClN3O5 C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2 InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Not reported 10 Male/Female oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity$indirect evidence-systemic toxicity RMS: Italy Propaquizafop 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P) 17Mar2009 2009 doi:10.2903/j.efsa.2009.204r
+Propaquizafop 111479-05-1 single chemical entity Component is identical to the substance Propaquizafop 111479-05-1 2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate Propaquizafop C22H22ClN3O5 C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2 InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Not reported 10 Male/Female oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Positive no evidence RMS: Italy Propaquizafop 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P) 17Mar2009 2009 doi:10.2903/j.efsa.2009.204r
+Propaquizafop 111479-05-1 single chemical entity Component is identical to the substance Propaquizafop 111479-05-1 2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate Propaquizafop C22H22ClN3O5 C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2 InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable Hamster (as animal) Chinese 5 Male oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Positive direct evidence-cytotoxicity RMS: Italy Propaquizafop 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P) 17Mar2009 2009 doi:10.2903/j.efsa.2009.204r
+Propaquizafop 111479-05-1 single chemical entity Component is identical to the substance Propaquizafop 111479-05-1 2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate Propaquizafop C22H22ClN3O5 C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2 InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable Hamster (as animal) Chinese 5 Male oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Italy Propaquizafop 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P) 17Mar2009 2009 doi:10.2903/j.efsa.2009.204r
+Propaquizafop 111479-05-1 single chemical entity Component is identical to the substance Propaquizafop 111479-05-1 2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate Propaquizafop C22H22ClN3O5 C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2 InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1 organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Hamster (as animal) Chinese 12 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Positive RMS: Italy Propaquizafop 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P) 17Mar2009 2009 doi:10.2903/j.efsa.2009.204r
+Propaquizafop 111479-05-1 single chemical entity Component is identical to the substance Propaquizafop 111479-05-1 2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate Propaquizafop C22H22ClN3O5 C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2 InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1 organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Hamster (as animal) Chinese 12 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Italy Propaquizafop 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P) 17Mar2009 2009 doi:10.2903/j.efsa.2009.204r
+Propaquizafop 111479-05-1 single chemical entity Component is identical to the substance Propaquizafop 111479-05-1 2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate Propaquizafop C22H22ClN3O5 C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2 InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1 organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Hamster (as animal) Chinese 12 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Italy Propaquizafop 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P) 17Mar2009 2009 doi:10.2903/j.efsa.2009.204r
+Propaquizafop 111479-05-1 single chemical entity Component is identical to the substance Propaquizafop 111479-05-1 2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate Propaquizafop C22H22ClN3O5 C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2 InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1 organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Hamster (as animal) Chinese 12 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Italy Propaquizafop 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P) 17Mar2009 2009 doi:10.2903/j.efsa.2009.204r
+Propaquizafop 111479-05-1 single chemical entity Component is identical to the substance Propaquizafop 111479-05-1 2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate Propaquizafop C22H22ClN3O5 C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2 InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1 organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Hamster (as animal) Chinese 12 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Positive RMS: Italy Propaquizafop 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P) 17Mar2009 2009 doi:10.2903/j.efsa.2009.204r
+Propaquizafop 111479-05-1 single chemical entity Component is identical to the substance Propaquizafop 111479-05-1 2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate Propaquizafop C22H22ClN3O5 C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2 InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1 organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Hamster (as animal) Chinese 12 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Italy Propaquizafop 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P) 17Mar2009 2009 doi:10.2903/j.efsa.2009.204r
+Propaquizafop 111479-05-1 single chemical entity Component is identical to the substance Propaquizafop 111479-05-1 2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate Propaquizafop C22H22ClN3O5 C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2 InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1 organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Hamster (as animal) Chinese 12 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Ambiguous RMS: Italy Propaquizafop 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P) 17Mar2009 2009 doi:10.2903/j.efsa.2009.204r
+Propaquizafop 111479-05-1 single chemical entity Component is identical to the substance Propaquizafop 111479-05-1 2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate Propaquizafop C22H22ClN3O5 C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2 InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1 organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Hamster (as animal) Chinese 12 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Italy Propaquizafop 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P) 17Mar2009 2009 doi:10.2903/j.efsa.2009.204r
+Propaquizafop 111479-05-1 single chemical entity Component is identical to the substance Propaquizafop 111479-05-1 2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate Propaquizafop C22H22ClN3O5 C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2 InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1 organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Hamster (as animal) Chinese 12 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Italy Propaquizafop 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P) 17Mar2009 2009 doi:10.2903/j.efsa.2009.204r
+Propaquizafop 111479-05-1 single chemical entity Component is identical to the substance Propaquizafop 111479-05-1 2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate Propaquizafop C22H22ClN3O5 C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2 InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1 organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Hamster (as animal) Chinese 12 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Positive RMS: Italy Propaquizafop 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P) 17Mar2009 2009 doi:10.2903/j.efsa.2009.204r
+Propamocarb hydrochloride 247-125-9 25606-41-1 single chemical entity Component is identical to the substance Propamocarb hydrochloride 247-125-9 25606-41-1 Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride N-desmethyl propamocarb C9H21ClN2O2 CCCOC(=O)NCCC[NH+](C)C.[Cl-] InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Ireland Propamocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb 05Jul2006 2006 doi:10.2903/j.efsa.2006.78r
+Propamocarb hydrochloride 247-125-9 25606-41-1 single chemical entity Component is identical to the substance Propamocarb hydrochloride 247-125-9 25606-41-1 Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride N-desmethyl propamocarb C9H21ClN2O2 CCCOC(=O)NCCC[NH+](C)C.[Cl-] InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Ireland Propamocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb 05Jul2006 2006 doi:10.2903/j.efsa.2006.78r
+Propamocarb hydrochloride 247-125-9 25606-41-1 single chemical entity Component is identical to the substance Propamocarb hydrochloride 247-125-9 25606-41-1 Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride N-desmethyl propamocarb C9H21ClN2O2 CCCOC(=O)NCCC[NH+](C)C.[Cl-] InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Ireland Propamocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb 05Jul2006 2006 doi:10.2903/j.efsa.2006.78r
+Propamocarb hydrochloride 247-125-9 25606-41-1 single chemical entity Component is identical to the substance Propamocarb hydrochloride 247-125-9 25606-41-1 Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride N-desmethyl propamocarb C9H21ClN2O2 CCCOC(=O)NCCC[NH+](C)C.[Cl-] InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Ireland Propamocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb 05Jul2006 2006 doi:10.2903/j.efsa.2006.78r
+Propamocarb hydrochloride 247-125-9 25606-41-1 single chemical entity Component is identical to the substance Propamocarb hydrochloride 247-125-9 25606-41-1 Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride N-desmethyl propamocarb C9H21ClN2O2 CCCOC(=O)NCCC[NH+](C)C.[Cl-] InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: Ireland Propamocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb 05Jul2006 2006 doi:10.2903/j.efsa.2006.78r
+Propamocarb hydrochloride 247-125-9 25606-41-1 single chemical entity Component is identical to the substance Propamocarb hydrochloride 247-125-9 25606-41-1 Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride N-desmethyl propamocarb C9H21ClN2O2 CCCOC(=O)NCCC[NH+](C)C.[Cl-] InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: Ireland Propamocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb 05Jul2006 2006 doi:10.2903/j.efsa.2006.78r
+Propamocarb hydrochloride 247-125-9 25606-41-1 single chemical entity Component is identical to the substance Propamocarb hydrochloride 247-125-9 25606-41-1 Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride N-desmethyl propamocarb C9H21ClN2O2 CCCOC(=O)NCCC[NH+](C)C.[Cl-] InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Ireland Propamocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb 05Jul2006 2006 doi:10.2903/j.efsa.2006.78r
+Propamocarb hydrochloride 247-125-9 25606-41-1 single chemical entity Component is identical to the substance Propamocarb hydrochloride 247-125-9 25606-41-1 Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride N-desmethyl propamocarb C9H21ClN2O2 CCCOC(=O)NCCC[NH+](C)C.[Cl-] InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: Ireland Propamocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb 05Jul2006 2006 doi:10.2903/j.efsa.2006.78r
+Propamocarb hydrochloride 247-125-9 25606-41-1 single chemical entity Component is identical to the substance Propamocarb hydrochloride 247-125-9 25606-41-1 Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride N-desmethyl propamocarb C9H21ClN2O2 CCCOC(=O)NCCC[NH+](C)C.[Cl-] InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: Ireland Propamocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb 05Jul2006 2006 doi:10.2903/j.efsa.2006.78r
+Propamocarb hydrochloride 247-125-9 25606-41-1 single chemical entity Component is identical to the substance Propamocarb hydrochloride 247-125-9 25606-41-1 Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride N-desmethyl propamocarb C9H21ClN2O2 CCCOC(=O)NCCC[NH+](C)C.[Cl-] InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Ireland Propamocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb 05Jul2006 2006 doi:10.2903/j.efsa.2006.78r
+Propamocarb hydrochloride 247-125-9 25606-41-1 single chemical entity Component is identical to the substance Propamocarb hydrochloride 247-125-9 25606-41-1 Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride N-desmethyl propamocarb C9H21ClN2O2 CCCOC(=O)NCCC[NH+](C)C.[Cl-] InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Ireland Propamocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb 05Jul2006 2006 doi:10.2903/j.efsa.2006.78r
+Propamocarb hydrochloride 247-125-9 25606-41-1 single chemical entity Component is identical to the substance Propamocarb hydrochloride 247-125-9 25606-41-1 Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride N-desmethyl propamocarb C9H21ClN2O2 CCCOC(=O)NCCC[NH+](C)C.[Cl-] InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Ireland Propamocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb 05Jul2006 2006 doi:10.2903/j.efsa.2006.78r
+Propamocarb hydrochloride 247-125-9 25606-41-1 single chemical entity Component is identical to the substance Propamocarb hydrochloride 247-125-9 25606-41-1 Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride N-desmethyl propamocarb C9H21ClN2O2 CCCOC(=O)NCCC[NH+](C)C.[Cl-] InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Ireland Propamocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb 05Jul2006 2006 doi:10.2903/j.efsa.2006.78r
+Propamocarb hydrochloride 247-125-9 25606-41-1 single chemical entity Component is identical to the substance Propamocarb hydrochloride 247-125-9 25606-41-1 Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride N-desmethyl propamocarb C9H21ClN2O2 CCCOC(=O)NCCC[NH+](C)C.[Cl-] InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Ireland Propamocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb 05Jul2006 2006 doi:10.2903/j.efsa.2006.78r
+Propamocarb hydrochloride 247-125-9 25606-41-1 single chemical entity Component is identical to the substance Propamocarb hydrochloride 247-125-9 25606-41-1 Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride N-desmethyl propamocarb C9H21ClN2O2 CCCOC(=O)NCCC[NH+](C)C.[Cl-] InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Ireland Propamocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb 05Jul2006 2006 doi:10.2903/j.efsa.2006.78r
+Propamocarb hydrochloride 247-125-9 25606-41-1 single chemical entity Component is identical to the substance Propamocarb hydrochloride 247-125-9 25606-41-1 Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride N-desmethyl propamocarb C9H21ClN2O2 CCCOC(=O)NCCC[NH+](C)C.[Cl-] InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Ireland Propamocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb 05Jul2006 2006 doi:10.2903/j.efsa.2006.78r
+Propamocarb hydrochloride 247-125-9 25606-41-1 single chemical entity Component is identical to the substance Propamocarb hydrochloride 247-125-9 25606-41-1 Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride N-desmethyl propamocarb C9H21ClN2O2 CCCOC(=O)NCCC[NH+](C)C.[Cl-] InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Ireland Propamocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb 05Jul2006 2006 doi:10.2903/j.efsa.2006.78r
+Propamocarb hydrochloride 247-125-9 25606-41-1 single chemical entity Component is identical to the substance Propamocarb hydrochloride 247-125-9 25606-41-1 Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride N-desmethyl propamocarb C9H21ClN2O2 CCCOC(=O)NCCC[NH+](C)C.[Cl-] InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: Ireland Propamocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb 05Jul2006 2006 doi:10.2903/j.efsa.2006.78r
+Propamocarb hydrochloride 247-125-9 25606-41-1 single chemical entity Component is identical to the substance Propamocarb hydrochloride 247-125-9 25606-41-1 Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride N-desmethyl propamocarb C9H21ClN2O2 CCCOC(=O)NCCC[NH+](C)C.[Cl-] InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Ireland Propamocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb 05Jul2006 2006 doi:10.2903/j.efsa.2006.78r
+Propamocarb hydrochloride 247-125-9 25606-41-1 single chemical entity Component is identical to the substance Propamocarb hydrochloride 247-125-9 25606-41-1 Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride N-desmethyl propamocarb C9H21ClN2O2 CCCOC(=O)NCCC[NH+](C)C.[Cl-] InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: Ireland Propamocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb 05Jul2006 2006 doi:10.2903/j.efsa.2006.78r
+Propamocarb hydrochloride 247-125-9 25606-41-1 single chemical entity Component is identical to the substance Propamocarb hydrochloride 247-125-9 25606-41-1 Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride N-desmethyl propamocarb C9H21ClN2O2 CCCOC(=O)NCCC[NH+](C)C.[Cl-] InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Ireland Propamocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb 05Jul2006 2006 doi:10.2903/j.efsa.2006.78r
+Propamocarb hydrochloride 247-125-9 25606-41-1 single chemical entity Component is identical to the substance Propamocarb hydrochloride 247-125-9 25606-41-1 Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride N-desmethyl propamocarb C9H21ClN2O2 CCCOC(=O)NCCC[NH+](C)C.[Cl-] InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Ireland Propamocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb 05Jul2006 2006 doi:10.2903/j.efsa.2006.78r
+Propamocarb hydrochloride 247-125-9 25606-41-1 single chemical entity Component is identical to the substance Propamocarb hydrochloride 247-125-9 25606-41-1 Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride N-desmethyl propamocarb C9H21ClN2O2 CCCOC(=O)NCCC[NH+](C)C.[Cl-] InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Ireland Propamocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb 05Jul2006 2006 doi:10.2903/j.efsa.2006.78r
+Propamocarb hydrochloride 247-125-9 25606-41-1 single chemical entity Component is identical to the substance Propamocarb hydrochloride 247-125-9 25606-41-1 Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride N-desmethyl propamocarb C9H21ClN2O2 CCCOC(=O)NCCC[NH+](C)C.[Cl-] InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Ireland Propamocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb 05Jul2006 2006 doi:10.2903/j.efsa.2006.78r
+Propamocarb hydrochloride 247-125-9 25606-41-1 single chemical entity Component is identical to the substance Propamocarb hydrochloride 247-125-9 25606-41-1 Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride N-desmethyl propamocarb C9H21ClN2O2 CCCOC(=O)NCCC[NH+](C)C.[Cl-] InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Ireland Propamocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb 05Jul2006 2006 doi:10.2903/j.efsa.2006.78r
+Propamocarb hydrochloride 247-125-9 25606-41-1 single chemical entity Component is identical to the substance Propamocarb hydrochloride 247-125-9 25606-41-1 Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride N-desmethyl propamocarb C9H21ClN2O2 CCCOC(=O)NCCC[NH+](C)C.[Cl-] InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Ireland Propamocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb 05Jul2006 2006 doi:10.2903/j.efsa.2006.78r
+Propamocarb hydrochloride 247-125-9 25606-41-1 single chemical entity Component is identical to the substance Propamocarb hydrochloride 247-125-9 25606-41-1 Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride N-desmethyl propamocarb C9H21ClN2O2 CCCOC(=O)NCCC[NH+](C)C.[Cl-] InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Ireland Propamocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb 05Jul2006 2006 doi:10.2903/j.efsa.2006.78r
+Propamocarb hydrochloride 247-125-9 25606-41-1 single chemical entity Component is identical to the substance Propamocarb hydrochloride 247-125-9 25606-41-1 Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride N-desmethyl propamocarb C9H21ClN2O2 CCCOC(=O)NCCC[NH+](C)C.[Cl-] InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Ireland Propamocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb 05Jul2006 2006 doi:10.2903/j.efsa.2006.78r
+Propamocarb hydrochloride 247-125-9 25606-41-1 single chemical entity Component is identical to the substance Propamocarb hydrochloride 247-125-9 25606-41-1 Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride N-desmethyl propamocarb C9H21ClN2O2 CCCOC(=O)NCCC[NH+](C)C.[Cl-] InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: Ireland Propamocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb 05Jul2006 2006 doi:10.2903/j.efsa.2006.78r
+Propamocarb hydrochloride 247-125-9 25606-41-1 single chemical entity Component is identical to the substance Propamocarb hydrochloride 247-125-9 25606-41-1 Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride N-desmethyl propamocarb C9H21ClN2O2 CCCOC(=O)NCCC[NH+](C)C.[Cl-] InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: Ireland Propamocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb 05Jul2006 2006 doi:10.2903/j.efsa.2006.78r
+Propamocarb hydrochloride 247-125-9 25606-41-1 single chemical entity Component is identical to the substance Propamocarb hydrochloride 247-125-9 25606-41-1 Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride N-desmethyl propamocarb C9H21ClN2O2 CCCOC(=O)NCCC[NH+](C)C.[Cl-] InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: Ireland Propamocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb 05Jul2006 2006 doi:10.2903/j.efsa.2006.78r
+Propamocarb hydrochloride 247-125-9 25606-41-1 single chemical entity Component is identical to the substance Propamocarb hydrochloride 247-125-9 25606-41-1 Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride N-desmethyl propamocarb C9H21ClN2O2 CCCOC(=O)NCCC[NH+](C)C.[Cl-] InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Ireland Propamocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb 05Jul2006 2006 doi:10.2903/j.efsa.2006.78r
+Propamocarb hydrochloride 247-125-9 25606-41-1 single chemical entity Component is identical to the substance Propamocarb hydrochloride 247-125-9 25606-41-1 Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride N-desmethyl propamocarb C9H21ClN2O2 CCCOC(=O)NCCC[NH+](C)C.[Cl-] InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: Ireland Propamocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb 05Jul2006 2006 doi:10.2903/j.efsa.2006.78r
+Propamocarb hydrochloride 247-125-9 25606-41-1 single chemical entity Component is identical to the substance Propamocarb hydrochloride 247-125-9 25606-41-1 Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride N-desmethyl propamocarb C9H21ClN2O2 CCCOC(=O)NCCC[NH+](C)C.[Cl-] InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Ireland Propamocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb 05Jul2006 2006 doi:10.2903/j.efsa.2006.78r
+Propamocarb hydrochloride 247-125-9 25606-41-1 single chemical entity Component is identical to the substance Propamocarb hydrochloride 247-125-9 25606-41-1 Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride N-desmethyl propamocarb C9H21ClN2O2 CCCOC(=O)NCCC[NH+](C)C.[Cl-] InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: Ireland Propamocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb 05Jul2006 2006 doi:10.2903/j.efsa.2006.78r
+Propamocarb hydrochloride 247-125-9 25606-41-1 single chemical entity Component is identical to the substance Propamocarb hydrochloride 247-125-9 25606-41-1 Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride N-desmethyl propamocarb C9H21ClN2O2 CCCOC(=O)NCCC[NH+](C)C.[Cl-] InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: Ireland Propamocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb 05Jul2006 2006 doi:10.2903/j.efsa.2006.78r
+Propamocarb hydrochloride 247-125-9 25606-41-1 single chemical entity Component is identical to the substance Propamocarb hydrochloride 247-125-9 25606-41-1 Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride N-desmethyl propamocarb C9H21ClN2O2 CCCOC(=O)NCCC[NH+](C)C.[Cl-] InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes without Negative RMS: Ireland Propamocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb 05Jul2006 2006 doi:10.2903/j.efsa.2006.78r
+Propamocarb hydrochloride 247-125-9 25606-41-1 single chemical entity Component is identical to the substance Propamocarb hydrochloride 247-125-9 25606-41-1 Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride N-desmethyl propamocarb C9H21ClN2O2 CCCOC(=O)NCCC[NH+](C)C.[Cl-] InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes with Negative RMS: Ireland Propamocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb 05Jul2006 2006 doi:10.2903/j.efsa.2006.78r
+Propamocarb hydrochloride 247-125-9 25606-41-1 single chemical entity Component is identical to the substance Propamocarb hydrochloride 247-125-9 25606-41-1 Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride N-desmethyl propamocarb C9H21ClN2O2 CCCOC(=O)NCCC[NH+](C)C.[Cl-] InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes without Negative RMS: Ireland Propamocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb 05Jul2006 2006 doi:10.2903/j.efsa.2006.78r
+Propamocarb hydrochloride 247-125-9 25606-41-1 single chemical entity Component is identical to the substance Propamocarb hydrochloride 247-125-9 25606-41-1 Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride N-desmethyl propamocarb C9H21ClN2O2 CCCOC(=O)NCCC[NH+](C)C.[Cl-] InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes with Negative RMS: Ireland Propamocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb 05Jul2006 2006 doi:10.2903/j.efsa.2006.78r
+Propamocarb hydrochloride 247-125-9 25606-41-1 single chemical entity Component is identical to the substance Propamocarb hydrochloride 247-125-9 25606-41-1 Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride N-desmethyl propamocarb C9H21ClN2O2 CCCOC(=O)NCCC[NH+](C)C.[Cl-] InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative no information RMS: Ireland Propamocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb 05Jul2006 2006 doi:10.2903/j.efsa.2006.78r
+Propamocarb hydrochloride 247-125-9 25606-41-1 single chemical entity Component is identical to the substance Propamocarb hydrochloride 247-125-9 25606-41-1 Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride N-desmethyl propamocarb C9H21ClN2O2 CCCOC(=O)NCCC[NH+](C)C.[Cl-] InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Negative no information RMS: Ireland Propamocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb 05Jul2006 2006 doi:10.2903/j.efsa.2006.78r
+Propamocarb hydrochloride 247-125-9 25606-41-1 single chemical entity Component is identical to the substance Propamocarb hydrochloride 247-125-9 25606-41-1 Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride N-desmethyl propamocarb C9H21ClN2O2 CCCOC(=O)NCCC[NH+](C)C.[Cl-] InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Negative no information RMS: Ireland Propamocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb 05Jul2006 2006 doi:10.2903/j.efsa.2006.78r
+Propamocarb hydrochloride 247-125-9 25606-41-1 single chemical entity Component is identical to the substance Propamocarb hydrochloride 247-125-9 25606-41-1 Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride N-desmethyl propamocarb C9H21ClN2O2 CCCOC(=O)NCCC[NH+](C)C.[Cl-] InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative no information RMS: Ireland Propamocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb 05Jul2006 2006 doi:10.2903/j.efsa.2006.78r
+Propamocarb hydrochloride 247-125-9 25606-41-1 single chemical entity Component is identical to the substance Propamocarb hydrochloride 247-125-9 25606-41-1 Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride N-desmethyl propamocarb C9H21ClN2O2 CCCOC(=O)NCCC[NH+](C)C.[Cl-] InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 36.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity RMS: Ireland Propamocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb 05Jul2006 2006 doi:10.2903/j.efsa.2006.78r
+Propamocarb hydrochloride 247-125-9 25606-41-1 single chemical entity Component is identical to the substance Propamocarb hydrochloride 247-125-9 25606-41-1 Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride N-desmethyl propamocarb C9H21ClN2O2 CCCOC(=O)NCCC[NH+](C)C.[Cl-] InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity RMS: Ireland Propamocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb 05Jul2006 2006 doi:10.2903/j.efsa.2006.78r
+Propamocarb hydrochloride 247-125-9 25606-41-1 single chemical entity Component is identical to the substance Propamocarb hydrochloride 247-125-9 25606-41-1 Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride N-desmethyl propamocarb C9H21ClN2O2 CCCOC(=O)NCCC[NH+](C)C.[Cl-] InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 12.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity RMS: Ireland Propamocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb 05Jul2006 2006 doi:10.2903/j.efsa.2006.78r
+Propamocarb hydrochloride 247-125-9 25606-41-1 single chemical entity Component is identical to the substance Propamocarb hydrochloride 247-125-9 25606-41-1 Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride N-desmethyl propamocarb C9H21ClN2O2 CCCOC(=O)NCCC[NH+](C)C.[Cl-] InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CFLP 10 Male/Female oral: gavage 6.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity RMS: Ireland Propamocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb 05Jul2006 2006 doi:10.2903/j.efsa.2006.78r
+Propamocarb hydrochloride 247-125-9 25606-41-1 single chemical entity Component is identical to the substance Propamocarb hydrochloride 247-125-9 25606-41-1 Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride N-desmethyl propamocarb C9H21ClN2O2 CCCOC(=O)NCCC[NH+](C)C.[Cl-] InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity RMS: Ireland Propamocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb 05Jul2006 2006 doi:10.2903/j.efsa.2006.78r
+Propamocarb hydrochloride 247-125-9 25606-41-1 single chemical entity Component is identical to the substance Propamocarb hydrochloride 247-125-9 25606-41-1 Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride N-desmethyl propamocarb C9H21ClN2O2 CCCOC(=O)NCCC[NH+](C)C.[Cl-] InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 6 Male/Female intraperitoneal 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Ireland Propamocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb 05Jul2006 2006 doi:10.2903/j.efsa.2006.78r
+Propamocarb hydrochloride 247-125-9 25606-41-1 single chemical entity Component is identical to the substance Propamocarb hydrochloride 247-125-9 25606-41-1 Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride N-desmethyl propamocarb C9H21ClN2O2 CCCOC(=O)NCCC[NH+](C)C.[Cl-] InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 6 Male/Female intraperitoneal 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Ireland Propamocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb 05Jul2006 2006 doi:10.2903/j.efsa.2006.78r
+Propamocarb hydrochloride 247-125-9 25606-41-1 single chemical entity Component is identical to the substance Propamocarb hydrochloride 247-125-9 25606-41-1 Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride N-desmethyl propamocarb C9H21ClN2O2 CCCOC(=O)NCCC[NH+](C)C.[Cl-] InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) No data Acceptable House mouse (as animal) ICR 25 Male oral: drinking water 8.0000000000 week yes not applicable Negative RMS: Ireland Propamocarb 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb 05Jul2006 2006 doi:10.2903/j.efsa.2006.78r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is identical to the substance Metribuzin 244-209-7 21087-64-9 4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one Metribuzin C8H14N4OS CC(C)(C)C1=NN=C(N(C1=O)N)SC InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes without Negative RMS: Germany Metribuzin 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is identical to the substance Metribuzin 244-209-7 21087-64-9 4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one Metribuzin C8H14N4OS CC(C)(C)C1=NN=C(N(C1=O)N)SC InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes without Negative RMS: Germany Metribuzin 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is identical to the substance Metribuzin 244-209-7 21087-64-9 4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one Metribuzin C8H14N4OS CC(C)(C)C1=NN=C(N(C1=O)N)SC InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Germany Metribuzin 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is identical to the substance Metribuzin 244-209-7 21087-64-9 4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one Metribuzin C8H14N4OS CC(C)(C)C1=NN=C(N(C1=O)N)SC InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes with Negative RMS: Germany Metribuzin 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is identical to the substance Metribuzin 244-209-7 21087-64-9 4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one Metribuzin C8H14N4OS CC(C)(C)C1=NN=C(N(C1=O)N)SC InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Germany Metribuzin 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is identical to the substance Metribuzin 244-209-7 21087-64-9 4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one Metribuzin C8H14N4OS CC(C)(C)C1=NN=C(N(C1=O)N)SC InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Germany Metribuzin 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is identical to the substance Metribuzin 244-209-7 21087-64-9 4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one Metribuzin C8H14N4OS CC(C)(C)C1=NN=C(N(C1=O)N)SC InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Germany Metribuzin 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is identical to the substance Metribuzin 244-209-7 21087-64-9 4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one Metribuzin C8H14N4OS CC(C)(C)C1=NN=C(N(C1=O)N)SC InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Germany Metribuzin 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is identical to the substance Metribuzin 244-209-7 21087-64-9 4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one Metribuzin C8H14N4OS CC(C)(C)C1=NN=C(N(C1=O)N)SC InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Germany Metribuzin 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is identical to the substance Metribuzin 244-209-7 21087-64-9 4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one Metribuzin C8H14N4OS CC(C)(C)C1=NN=C(N(C1=O)N)SC InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Germany Metribuzin 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is identical to the substance Metribuzin 244-209-7 21087-64-9 4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one Metribuzin C8H14N4OS CC(C)(C)C1=NN=C(N(C1=O)N)SC InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Germany Metribuzin 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is identical to the substance Metribuzin 244-209-7 21087-64-9 4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one Metribuzin C8H14N4OS CC(C)(C)C1=NN=C(N(C1=O)N)SC InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes with Negative RMS: Germany Metribuzin 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is identical to the substance Metribuzin 244-209-7 21087-64-9 4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one Metribuzin C8H14N4OS CC(C)(C)C1=NN=C(N(C1=O)N)SC InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: Germany Metribuzin 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is identical to the substance Metribuzin 244-209-7 21087-64-9 4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one Metribuzin C8H14N4OS CC(C)(C)C1=NN=C(N(C1=O)N)SC InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: Germany Metribuzin 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is identical to the substance Metribuzin 244-209-7 21087-64-9 4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one Metribuzin C8H14N4OS CC(C)(C)C1=NN=C(N(C1=O)N)SC InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Germany Metribuzin 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is identical to the substance Metribuzin 244-209-7 21087-64-9 4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one Metribuzin C8H14N4OS CC(C)(C)C1=NN=C(N(C1=O)N)SC InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Germany Metribuzin 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is identical to the substance Metribuzin 244-209-7 21087-64-9 4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one Metribuzin C8H14N4OS CC(C)(C)C1=NN=C(N(C1=O)N)SC InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Germany Metribuzin 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is identical to the substance Metribuzin 244-209-7 21087-64-9 4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one Metribuzin C8H14N4OS CC(C)(C)C1=NN=C(N(C1=O)N)SC InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Germany Metribuzin 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is identical to the substance Metribuzin 244-209-7 21087-64-9 4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one Metribuzin C8H14N4OS CC(C)(C)C1=NN=C(N(C1=O)N)SC InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes without Negative RMS: Germany Metribuzin 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is identical to the substance Metribuzin 244-209-7 21087-64-9 4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one Metribuzin C8H14N4OS CC(C)(C)C1=NN=C(N(C1=O)N)SC InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes with Negative RMS: Germany Metribuzin 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is identical to the substance Metribuzin 244-209-7 21087-64-9 4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one Metribuzin C8H14N4OS CC(C)(C)C1=NN=C(N(C1=O)N)SC InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: Germany Metribuzin 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is identical to the substance Metribuzin 244-209-7 21087-64-9 4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one Metribuzin C8H14N4OS CC(C)(C)C1=NN=C(N(C1=O)N)SC InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: Germany Metribuzin 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is identical to the substance Metribuzin 244-209-7 21087-64-9 4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one Metribuzin C8H14N4OS CC(C)(C)C1=NN=C(N(C1=O)N)SC InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Germany Metribuzin 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is identical to the substance Metribuzin 244-209-7 21087-64-9 4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one Metribuzin C8H14N4OS CC(C)(C)C1=NN=C(N(C1=O)N)SC InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes without Negative RMS: Germany Metribuzin 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is identical to the substance Metribuzin 244-209-7 21087-64-9 4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one Metribuzin C8H14N4OS CC(C)(C)C1=NN=C(N(C1=O)N)SC InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Germany Metribuzin 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is identical to the substance Metribuzin 244-209-7 21087-64-9 4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one Metribuzin C8H14N4OS CC(C)(C)C1=NN=C(N(C1=O)N)SC InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Germany Metribuzin 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is identical to the substance Metribuzin 244-209-7 21087-64-9 4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one Metribuzin C8H14N4OS CC(C)(C)C1=NN=C(N(C1=O)N)SC InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Germany Metribuzin 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is identical to the substance Metribuzin 244-209-7 21087-64-9 4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one Metribuzin C8H14N4OS CC(C)(C)C1=NN=C(N(C1=O)N)SC InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes with Negative RMS: Germany Metribuzin 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is identical to the substance Metribuzin 244-209-7 21087-64-9 4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one Metribuzin C8H14N4OS CC(C)(C)C1=NN=C(N(C1=O)N)SC InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany Metribuzin 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is identical to the substance Metribuzin 244-209-7 21087-64-9 4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one Metribuzin C8H14N4OS CC(C)(C)C1=NN=C(N(C1=O)N)SC InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany Metribuzin 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is identical to the substance Metribuzin 244-209-7 21087-64-9 4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one Metribuzin C8H14N4OS CC(C)(C)C1=NN=C(N(C1=O)N)SC InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany Metribuzin 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is identical to the substance Metribuzin 244-209-7 21087-64-9 4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one Metribuzin C8H14N4OS CC(C)(C)C1=NN=C(N(C1=O)N)SC InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany Metribuzin 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is identical to the substance Metribuzin 244-209-7 21087-64-9 4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one Metribuzin C8H14N4OS CC(C)(C)C1=NN=C(N(C1=O)N)SC InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany Metribuzin 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is identical to the substance Metribuzin 244-209-7 21087-64-9 4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one Metribuzin C8H14N4OS CC(C)(C)C1=NN=C(N(C1=O)N)SC InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany Metribuzin 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is identical to the substance Metribuzin 244-209-7 21087-64-9 4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one Metribuzin C8H14N4OS CC(C)(C)C1=NN=C(N(C1=O)N)SC InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany Metribuzin 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is identical to the substance Metribuzin 244-209-7 21087-64-9 4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one Metribuzin C8H14N4OS CC(C)(C)C1=NN=C(N(C1=O)N)SC InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Germany Metribuzin 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is identical to the substance Metribuzin 244-209-7 21087-64-9 4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one Metribuzin C8H14N4OS CC(C)(C)C1=NN=C(N(C1=O)N)SC InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany Metribuzin 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is identical to the substance Metribuzin 244-209-7 21087-64-9 4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one Metribuzin C8H14N4OS CC(C)(C)C1=NN=C(N(C1=O)N)SC InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Germany Metribuzin 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is identical to the substance Metribuzin 244-209-7 21087-64-9 4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one Metribuzin C8H14N4OS CC(C)(C)C1=NN=C(N(C1=O)N)SC InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro According to OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay) No Acceptable Saccharomyces cerevisiae (as organism) D7 Not reported yes without Negative RMS: Germany Metribuzin 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is identical to the substance Metribuzin 244-209-7 21087-64-9 4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one Metribuzin C8H14N4OS CC(C)(C)C1=NN=C(N(C1=O)N)SC InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro According to OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay) No Acceptable Saccharomyces cerevisiae (as organism) D7 Not reported yes with Negative RMS: Germany Metribuzin 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is identical to the substance Metribuzin 244-209-7 21087-64-9 4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one Metribuzin C8H14N4OS CC(C)(C)C1=NN=C(N(C1=O)N)SC InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: Germany Metribuzin 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is identical to the substance Metribuzin 244-209-7 21087-64-9 4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one Metribuzin C8H14N4OS CC(C)(C)C1=NN=C(N(C1=O)N)SC InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: Germany Metribuzin 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is identical to the substance Metribuzin 244-209-7 21087-64-9 4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one Metribuzin C8H14N4OS CC(C)(C)C1=NN=C(N(C1=O)N)SC InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Germany Metribuzin 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is identical to the substance Metribuzin 244-209-7 21087-64-9 4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one Metribuzin C8H14N4OS CC(C)(C)C1=NN=C(N(C1=O)N)SC InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Positive RMS: Germany Metribuzin 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is identical to the substance Metribuzin 244-209-7 21087-64-9 4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one Metribuzin C8H14N4OS CC(C)(C)C1=NN=C(N(C1=O)N)SC InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Germany Metribuzin 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is identical to the substance Metribuzin 244-209-7 21087-64-9 4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one Metribuzin C8H14N4OS CC(C)(C)C1=NN=C(N(C1=O)N)SC InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Positive RMS: Germany Metribuzin 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is identical to the substance Metribuzin 244-209-7 21087-64-9 4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one Metribuzin C8H14N4OS CC(C)(C)C1=NN=C(N(C1=O)N)SC InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Germany Metribuzin 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is identical to the substance Metribuzin 244-209-7 21087-64-9 4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one Metribuzin C8H14N4OS CC(C)(C)C1=NN=C(N(C1=O)N)SC InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable House mouse (as animal) NMRI No data oral: gavage no data not applicable Negative no evidence RMS: Germany Metribuzin 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is identical to the substance Metribuzin 244-209-7 21087-64-9 4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one Metribuzin C8H14N4OS CC(C)(C)C1=NN=C(N(C1=O)N)SC InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable House mouse (as animal) Swiss 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Germany Metribuzin 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is identical to the substance Metribuzin 244-209-7 21087-64-9 4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one Metribuzin C8H14N4OS CC(C)(C)C1=NN=C(N(C1=O)N)SC InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Swiss 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity RMS: Germany Metribuzin 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is identical to the substance Metribuzin 244-209-7 21087-64-9 4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one Metribuzin C8H14N4OS CC(C)(C)C1=NN=C(N(C1=O)N)SC InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration mammalian germ cell cytogenetic assay in vivo Equivalent or similar to OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test) No data Acceptable Hamster (as animal) Chinese Male oral: unspecified no data not applicable Negative RMS: Germany Metribuzin 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is identical to the substance Metribuzin 244-209-7 21087-64-9 4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one Metribuzin C8H14N4OS CC(C)(C)C1=NN=C(N(C1=O)N)SC InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) Yes Acceptable House mouse (as animal) NMRI Female oral: gavage yes not applicable Negative RMS: Germany Metribuzin 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is identical to the substance Metribuzin 244-209-7 21087-64-9 4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one Metribuzin C8H14N4OS CC(C)(C)C1=NN=C(N(C1=O)N)SC InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) Yes Acceptable House mouse (as animal) NMRI Female oral: gavage yes not applicable Negative RMS: Germany Metribuzin 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is identical to the substance Metribuzin 244-209-7 21087-64-9 4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one Metribuzin C8H14N4OS CC(C)(C)C1=NN=C(N(C1=O)N)SC InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) No data Acceptable House mouse (as animal) NMRI Male oral: gavage yes not applicable Negative RMS: Germany Metribuzin 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is a metabolite of the substance desaminodiketo-metribuzin 6-tert-butyl-2H-1,2,4-triazine-3,5-dione Not in list C7H11N3O2 CC(C)(C)C1=NNC(=O)NC1=O InChI=1S/C7H11N3O2/c1-7(2,3)4-5(11)8-6(12)10-9-4/h1-3H3,(H2,8,10,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Germany Metribuzin (Addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is a metabolite of the substance desaminodiketo-metribuzin 6-tert-butyl-2H-1,2,4-triazine-3,5-dione Not in list C7H11N3O2 CC(C)(C)C1=NNC(=O)NC1=O InChI=1S/C7H11N3O2/c1-7(2,3)4-5(11)8-6(12)10-9-4/h1-3H3,(H2,8,10,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Germany Metribuzin (Addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is a metabolite of the substance desaminodiketo-metribuzin 6-tert-butyl-2H-1,2,4-triazine-3,5-dione Not in list C7H11N3O2 CC(C)(C)C1=NNC(=O)NC1=O InChI=1S/C7H11N3O2/c1-7(2,3)4-5(11)8-6(12)10-9-4/h1-3H3,(H2,8,10,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Germany Metribuzin (Addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is a metabolite of the substance desaminodiketo-metribuzin 6-tert-butyl-2H-1,2,4-triazine-3,5-dione Not in list C7H11N3O2 CC(C)(C)C1=NNC(=O)NC1=O InChI=1S/C7H11N3O2/c1-7(2,3)4-5(11)8-6(12)10-9-4/h1-3H3,(H2,8,10,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Germany Metribuzin (Addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is a metabolite of the substance desaminodiketo-metribuzin 6-tert-butyl-2H-1,2,4-triazine-3,5-dione Not in list C7H11N3O2 CC(C)(C)C1=NNC(=O)NC1=O InChI=1S/C7H11N3O2/c1-7(2,3)4-5(11)8-6(12)10-9-4/h1-3H3,(H2,8,10,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Germany Metribuzin (Addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is a metabolite of the substance desaminodiketo-metribuzin 6-tert-butyl-2H-1,2,4-triazine-3,5-dione Not in list C7H11N3O2 CC(C)(C)C1=NNC(=O)NC1=O InChI=1S/C7H11N3O2/c1-7(2,3)4-5(11)8-6(12)10-9-4/h1-3H3,(H2,8,10,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes without Negative RMS: Germany Metribuzin (Addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is a metabolite of the substance desaminodiketo-metribuzin 6-tert-butyl-2H-1,2,4-triazine-3,5-dione Not in list C7H11N3O2 CC(C)(C)C1=NNC(=O)NC1=O InChI=1S/C7H11N3O2/c1-7(2,3)4-5(11)8-6(12)10-9-4/h1-3H3,(H2,8,10,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes with Negative RMS: Germany Metribuzin (Addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is a metabolite of the substance desaminodiketo-metribuzin 6-tert-butyl-2H-1,2,4-triazine-3,5-dione Not in list C7H11N3O2 CC(C)(C)C1=NNC(=O)NC1=O InChI=1S/C7H11N3O2/c1-7(2,3)4-5(11)8-6(12)10-9-4/h1-3H3,(H2,8,10,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Germany Metribuzin (Addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is a metabolite of the substance desaminodiketo-metribuzin 6-tert-butyl-2H-1,2,4-triazine-3,5-dione Not in list C7H11N3O2 CC(C)(C)C1=NNC(=O)NC1=O InChI=1S/C7H11N3O2/c1-7(2,3)4-5(11)8-6(12)10-9-4/h1-3H3,(H2,8,10,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Germany Metribuzin (Addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is a metabolite of the substance desaminodiketo-metribuzin 6-tert-butyl-2H-1,2,4-triazine-3,5-dione Not in list C7H11N3O2 CC(C)(C)C1=NNC(=O)NC1=O InChI=1S/C7H11N3O2/c1-7(2,3)4-5(11)8-6(12)10-9-4/h1-3H3,(H2,8,10,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Germany Metribuzin (Addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is a metabolite of the substance desaminodiketo-metribuzin 6-tert-butyl-2H-1,2,4-triazine-3,5-dione Not in list C7H11N3O2 CC(C)(C)C1=NNC(=O)NC1=O InChI=1S/C7H11N3O2/c1-7(2,3)4-5(11)8-6(12)10-9-4/h1-3H3,(H2,8,10,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Negative no information RMS: Germany Metribuzin (Addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is a metabolite of the substance desaminodiketo-metribuzin 6-tert-butyl-2H-1,2,4-triazine-3,5-dione Not in list C7H11N3O2 CC(C)(C)C1=NNC(=O)NC1=O InChI=1S/C7H11N3O2/c1-7(2,3)4-5(11)8-6(12)10-9-4/h1-3H3,(H2,8,10,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative no information RMS: Germany Metribuzin (Addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is a metabolite of the substance desaminodiketo-metribuzin 6-tert-butyl-2H-1,2,4-triazine-3,5-dione Not in list C7H11N3O2 CC(C)(C)C1=NNC(=O)NC1=O InChI=1S/C7H11N3O2/c1-7(2,3)4-5(11)8-6(12)10-9-4/h1-3H3,(H2,8,10,11,12) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes without Negative RMS: Germany Metribuzin (Addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Metribuzin 244-209-7 21087-64-9 single chemical entity Component is a metabolite of the substance desaminodiketo-metribuzin 6-tert-butyl-2H-1,2,4-triazine-3,5-dione Not in list C7H11N3O2 CC(C)(C)C1=NNC(=O)NC1=O InChI=1S/C7H11N3O2/c1-7(2,3)4-5(11)8-6(12)10-9-4/h1-3H3,(H2,8,10,11,12) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes with Negative RMS: Germany Metribuzin (Addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin 18Sep2006 2006 doi:10.2903/j.efsa.2006.88r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Myclobutanil 88671-89-0 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Myclobutanil 88671-89-0 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 102 Not reported no data with Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 102 Not reported no data without Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Myclobutanil 88671-89-0 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 102 Not reported no data without Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 102 Not reported no data with Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 102 Not reported no data without Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 102 Not reported no data with Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 102 Not reported no data without Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 102 Not reported no data with Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 102 Not reported no data with Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 102 Not reported no data without Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 102 Not reported no data without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 102 Not reported no data with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 102 Not reported no data with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 102 Not reported no data without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data without Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data with Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data with Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data without Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Myclobutanil 88671-89-0 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data with Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data without Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data without Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data with Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair in vitro mammalian cell transformation assay in vitro No guideline available Not reported Not applicable Acceptable Hamster (as animal) fibroblast Not reported no data with Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair in vitro mammalian cell transformation assay in vitro No guideline available Not reported Not applicable Acceptable Hamster (as animal) fibroblast Not reported no data without Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair in vitro mammalian cell transformation assay in vitro No guideline available Not reported Not applicable Acceptable Hamster (as animal) fibroblast Not reported no data with Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair in vitro mammalian cell transformation assay in vitro No guideline available Not reported Not applicable Acceptable Hamster (as animal) fibroblast Not reported no data without Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair in vitro mammalian cell transformation assay in vitro No guideline available Not reported Not applicable Acceptable Hamster (as animal) fibroblast Not reported no data without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair in vitro mammalian cell transformation assay in vitro No guideline available Not reported Not applicable Acceptable Hamster (as animal) fibroblast Not reported no data with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair in vitro mammalian cell transformation assay in vitro No guideline available Not reported Not applicable Acceptable Hamster (as animal) fibroblast Not reported no data with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair in vitro mammalian cell transformation assay in vitro No guideline available Not reported Not applicable Acceptable Hamster (as animal) fibroblast Not reported no data without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair in vitro mammalian cell transformation assay in vitro No guideline available Not reported Not applicable Acceptable House mouse (as animal) fibroblast Not reported no data with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair in vitro mammalian cell transformation assay in vitro No guideline available Not reported Not applicable Acceptable House mouse (as animal) fibroblast Not reported no data without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair in vitro mammalian cell transformation assay in vitro No guideline available Not reported Not applicable Acceptable House mouse (as animal) fibroblast Not reported no data with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair in vitro mammalian cell transformation assay in vitro No guideline available Not reported Not applicable Acceptable House mouse (as animal) fibroblast Not reported no data without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair in vitro mammalian cell transformation assay in vitro No guideline available Not reported Not applicable Acceptable House mouse (as animal) fibroblast Not reported no data without Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair in vitro mammalian cell transformation assay in vitro No guideline available Not reported Not applicable Acceptable House mouse (as animal) fibroblast Not reported no data with Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair in vitro mammalian cell transformation assay in vitro No guideline available Not reported Not applicable Acceptable House mouse (as animal) fibroblast Not reported no data without Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair in vitro mammalian cell transformation assay in vitro No guideline available Not reported Not applicable Acceptable House mouse (as animal) fibroblast Not reported no data with Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair in vitro mammalian cell transformation assay in vitro No guideline available Not reported Not applicable Acceptable House mouse (as animal) fibroblast Not reported no data with Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair in vitro mammalian cell transformation assay in vitro No guideline available Not reported Not applicable Acceptable House mouse (as animal) fibroblast Not reported no data without Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair in vitro mammalian cell transformation assay in vitro No guideline available Not reported Not applicable Acceptable House mouse (as animal) fibroblast Not reported no data without Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair in vitro mammalian cell transformation assay in vitro No guideline available Not reported Not applicable Acceptable House mouse (as animal) fibroblast Not reported no data with Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable House mouse (as animal) CF-1 5 Male oral: unspecified 48.0000000000 h no data not applicable Negative no evidence RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable House mouse (as animal) CF-1 5 Male oral: unspecified 72.0000000000 h no data not applicable Negative no evidence RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable House mouse (as animal) CF-1 5 Male intraperitoneal 24.0000000000 h no data not applicable Negative no evidence RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Myclobutanil 88671-89-0 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable House mouse (as animal) CF-1 5 Male oral: unspecified 48.0000000000 h no data not applicable Negative no evidence RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable House mouse (as animal) CF-1 5 Male intraperitoneal 24.0000000000 h no data not applicable Negative no evidence RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable House mouse (as animal) CF-1 5 Male oral: unspecified 72.0000000000 h no data not applicable Negative no evidence RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable House mouse (as animal) CF-1 5 Male oral: unspecified 72.0000000000 h no data not applicable Negative no evidence RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable House mouse (as animal) CF-1 5 Male oral: unspecified 48.0000000000 h no data not applicable Negative no evidence RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable House mouse (as animal) CF-1 5 Male intraperitoneal 24.0000000000 h no data not applicable Negative no evidence RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable House mouse (as animal) CF-1 5 Male oral: unspecified 48.0000000000 h no data not applicable Negative no evidence RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable House mouse (as animal) CF-1 5 Male oral: unspecified 72.0000000000 h no data not applicable Negative no evidence RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable House mouse (as animal) CF-1 5 Male intraperitoneal 24.0000000000 h no data not applicable Negative no evidence RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable House mouse (as animal) CF-1 5 Male intraperitoneal 24.0000000000 h no data not applicable Negative no evidence RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable House mouse (as animal) CF-1 5 Male oral: unspecified 72.0000000000 h no data not applicable Negative no evidence RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable House mouse (as animal) CF-1 5 Male oral: unspecified 48.0000000000 h no data not applicable Negative no evidence RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable House mouse (as animal) CF-1 5 Male intraperitoneal 24.0000000000 h no data not applicable Negative no evidence RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable House mouse (as animal) CF-1 5 Male oral: unspecified 72.0000000000 h no data not applicable Negative no evidence RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable House mouse (as animal) CF-1 5 Male oral: unspecified 48.0000000000 h no data not applicable Negative no evidence RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 72.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Ambiguous no evidence RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Ambiguous no evidence RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 72.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 72.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Ambiguous no evidence RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 72.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Ambiguous no evidence RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Myclobutanil 88671-89-0 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 72.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Ambiguous no evidence RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 72.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Ambiguous no evidence RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable Hamster (as animal) Chinese 16 Male/Female oral: unspecified 24.0000000000 h no data not applicable Negative no evidence RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable Hamster (as animal) Chinese 16 Male/Female oral: unspecified 16.0000000000 h no data not applicable Negative no evidence RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable Hamster (as animal) Chinese 16 Male/Female oral: unspecified 48.0000000000 h no data not applicable Negative no evidence RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Myclobutanil 88671-89-0 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable Hamster (as animal) Chinese 16 Male/Female oral: unspecified 48.0000000000 h no data not applicable Negative no evidence RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable Hamster (as animal) Chinese 16 Male/Female oral: unspecified 16.0000000000 h no data not applicable Negative no evidence RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable Hamster (as animal) Chinese 16 Male/Female oral: unspecified 24.0000000000 h no data not applicable Negative no evidence RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable Hamster (as animal) Chinese 16 Male/Female oral: unspecified 16.0000000000 h no data not applicable Negative no evidence RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable Hamster (as animal) Chinese 16 Male/Female oral: unspecified 24.0000000000 h no data not applicable Negative no evidence RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable Hamster (as animal) Chinese 16 Male/Female oral: unspecified 48.0000000000 h no data not applicable Negative no evidence RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable Hamster (as animal) Chinese 16 Male/Female oral: unspecified 48.0000000000 h no data not applicable Negative no evidence RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable Hamster (as animal) Chinese 16 Male/Female oral: unspecified 24.0000000000 h no data not applicable Negative no evidence RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable Hamster (as animal) Chinese 16 Male/Female oral: unspecified 16.0000000000 h no data not applicable Negative no evidence RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable Hamster (as animal) Chinese 16 Male/Female oral: unspecified 24.0000000000 h no data not applicable Negative no evidence RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable Hamster (as animal) Chinese 16 Male/Female oral: unspecified 16.0000000000 h no data not applicable Negative no evidence RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable Hamster (as animal) Chinese 16 Male/Female oral: unspecified 48.0000000000 h no data not applicable Negative no evidence RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable Hamster (as animal) Chinese 16 Male/Female oral: unspecified 48.0000000000 h no data not applicable Negative no evidence RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable Hamster (as animal) Chinese 16 Male/Female oral: unspecified 24.0000000000 h no data not applicable Negative no evidence RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable Hamster (as animal) Chinese 16 Male/Female oral: unspecified 16.0000000000 h no data not applicable Negative no evidence RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable Hamster (as animal) Chinese 16 Male/Female oral: unspecified 24.0000000000 h no data not applicable Negative no evidence RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable Hamster (as animal) Chinese 16 Male/Female oral: unspecified 48.0000000000 h no data not applicable Negative no evidence RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable Hamster (as animal) Chinese 16 Male/Female oral: unspecified 16.0000000000 h no data not applicable Negative no evidence RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) W3110 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) (k12)p3478 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) W3110 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) (k12)p3478 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) W3110 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) (k12)p3478 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) W3110 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) (k12)p3478 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) (k12)p3478 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) W3110 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) (k12)p3478 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) W3110 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) W3110 Not reported yes, concurrent vehicle without Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) (k12)p3478 Not reported yes, concurrent vehicle without Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) (k12)p3478 Not reported yes, concurrent vehicle with Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) W3110 Not reported yes, concurrent vehicle with Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No data Acceptable Hamster (as animal) hepatocytes Not reported no data without Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No data Acceptable Hamster (as animal) hepatocytes Not reported no data without Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Myclobutanil 88671-89-0 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No data Acceptable Hamster (as animal) hepatocytes Not reported no data without Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No data Acceptable Hamster (as animal) hepatocytes Not reported no data without Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No data Acceptable Hamster (as animal) hepatocytes Not reported no data without Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No data Acceptable Hamster (as animal) hepatocytes Not reported no data without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No data Acceptable Hamster (as animal) hepatocytes Not reported no data without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is identical to the substance Prochloraz 266-994-5 67747-09-5 N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide Prochloraz C15H16Cl3N3O2 O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2 InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) CM891 Not reported yes, concurrent vehicle with Negative RMS: Ireland Prochloraz 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is identical to the substance Prochloraz 266-994-5 67747-09-5 N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide Prochloraz C15H16Cl3N3O2 O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2 InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Ireland Prochloraz 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is identical to the substance Prochloraz 266-994-5 67747-09-5 N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide Prochloraz C15H16Cl3N3O2 O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2 InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Ireland Prochloraz 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is identical to the substance Prochloraz 266-994-5 67747-09-5 N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide Prochloraz C15H16Cl3N3O2 O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2 InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) CM891 Not reported yes, concurrent vehicle without Negative RMS: Ireland Prochloraz 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is identical to the substance Prochloraz 266-994-5 67747-09-5 N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide Prochloraz C15H16Cl3N3O2 O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2 InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Ireland Prochloraz 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is identical to the substance Prochloraz 266-994-5 67747-09-5 N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide Prochloraz C15H16Cl3N3O2 O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2 InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Ireland Prochloraz 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is identical to the substance Prochloraz 266-994-5 67747-09-5 N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide Prochloraz C15H16Cl3N3O2 O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2 InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Ireland Prochloraz 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is identical to the substance Prochloraz 266-994-5 67747-09-5 N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide Prochloraz C15H16Cl3N3O2 O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2 InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Ireland Prochloraz 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is identical to the substance Prochloraz 266-994-5 67747-09-5 N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide Prochloraz C15H16Cl3N3O2 O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2 InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Ireland Prochloraz 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is identical to the substance Prochloraz 266-994-5 67747-09-5 N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide Prochloraz C15H16Cl3N3O2 O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2 InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Ireland Prochloraz 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is the active ingredient of the mixture or formulation Prochloraz-Copper 156065-03-1 Dichlorotetrakids-[N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl] imidazole-1-carboxamide]copper(II) Not in list C60H64Cl14CuN12O8 organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Ireland Prochloraz 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is the active ingredient of the mixture or formulation Prochloraz-Copper 156065-03-1 Dichlorotetrakids-[N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl] imidazole-1-carboxamide]copper(II) Not in list C60H64Cl14CuN12O8 organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Ireland Prochloraz 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is the active ingredient of the mixture or formulation Prochloraz-Copper 156065-03-1 Dichlorotetrakids-[N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl] imidazole-1-carboxamide]copper(II) Not in list C60H64Cl14CuN12O8 organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Ireland Prochloraz 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is the active ingredient of the mixture or formulation Prochloraz-Copper 156065-03-1 Dichlorotetrakids-[N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl] imidazole-1-carboxamide]copper(II) Not in list C60H64Cl14CuN12O8 organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Ireland Prochloraz 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is the active ingredient of the mixture or formulation Prochloraz-Copper 156065-03-1 Dichlorotetrakids-[N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl] imidazole-1-carboxamide]copper(II) Not in list C60H64Cl14CuN12O8 organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Ireland Prochloraz 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is the active ingredient of the mixture or formulation Prochloraz-Copper 156065-03-1 Dichlorotetrakids-[N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl] imidazole-1-carboxamide]copper(II) Not in list C60H64Cl14CuN12O8 organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Ireland Prochloraz 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is the active ingredient of the mixture or formulation Prochloraz-Copper 156065-03-1 Dichlorotetrakids-[N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl] imidazole-1-carboxamide]copper(II) Not in list C60H64Cl14CuN12O8 organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Ireland Prochloraz 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is the active ingredient of the mixture or formulation Prochloraz-Copper 156065-03-1 Dichlorotetrakids-[N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl] imidazole-1-carboxamide]copper(II) Not in list C60H64Cl14CuN12O8 organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Ireland Prochloraz 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is the active ingredient of the mixture or formulation Prochloraz-Copper 156065-03-1 Dichlorotetrakids-[N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl] imidazole-1-carboxamide]copper(II) Not in list C60H64Cl14CuN12O8 organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) CM891 Not reported yes, concurrent vehicle with Negative RMS: Ireland Prochloraz 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is the active ingredient of the mixture or formulation Prochloraz-Copper 156065-03-1 Dichlorotetrakids-[N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl] imidazole-1-carboxamide]copper(II) Not in list C60H64Cl14CuN12O8 organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) CM891 Not reported yes, concurrent vehicle without Negative RMS: Ireland Prochloraz 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is identical to the substance Prochloraz 266-994-5 67747-09-5 N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide Prochloraz C15H16Cl3N3O2 O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2 InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative no information RMS: Ireland Prochloraz 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is identical to the substance Prochloraz 266-994-5 67747-09-5 N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide Prochloraz C15H16Cl3N3O2 O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2 InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Positive no information RMS: Ireland Prochloraz 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is identical to the substance Prochloraz 266-994-5 67747-09-5 N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide Prochloraz C15H16Cl3N3O2 O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2 InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative no information RMS: Ireland Prochloraz 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is identical to the substance Prochloraz 266-994-5 67747-09-5 N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide Prochloraz C15H16Cl3N3O2 O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2 InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Negative no information RMS: Ireland Prochloraz 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is identical to the substance Prochloraz 266-994-5 67747-09-5 N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide Prochloraz C15H16Cl3N3O2 O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2 InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported no data without Negative RMS: Ireland Prochloraz 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is identical to the substance Prochloraz 266-994-5 67747-09-5 N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide Prochloraz C15H16Cl3N3O2 O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2 InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported no data with Negative RMS: Ireland Prochloraz 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is identical to the substance Prochloraz 266-994-5 67747-09-5 N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide Prochloraz C15H16Cl3N3O2 O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2 InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3 organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro According to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Positive RMS: Ireland Prochloraz 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is identical to the substance Prochloraz 266-994-5 67747-09-5 N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide Prochloraz C15H16Cl3N3O2 O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2 InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3 organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro According to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Positive RMS: Ireland Prochloraz 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is identical to the substance Prochloraz 266-994-5 67747-09-5 N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide Prochloraz C15H16Cl3N3O2 O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2 InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3 organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Human (as organism) fibroblast Not reported yes, concurrent vehicle without Negative RMS: Ireland Prochloraz 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is identical to the substance Prochloraz 266-994-5 67747-09-5 N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide Prochloraz C15H16Cl3N3O2 O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2 InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3 organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Human (as organism) fibroblast Not reported yes, concurrent vehicle with Negative RMS: Ireland Prochloraz 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is identical to the substance Prochloraz 266-994-5 67747-09-5 N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide Prochloraz C15H16Cl3N3O2 O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2 InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 30 Male/Female oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity$indirect evidence-systemic toxicity RMS: Ireland Prochloraz 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is identical to the substance Prochloraz 266-994-5 67747-09-5 N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide Prochloraz C15H16Cl3N3O2 O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2 InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 30 Male/Female oral: unspecified 72.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity$indirect evidence-systemic toxicity RMS: Ireland Prochloraz 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is identical to the substance Prochloraz 266-994-5 67747-09-5 N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide Prochloraz C15H16Cl3N3O2 O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2 InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 30 Male/Female oral: unspecified 48.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity$indirect evidence-systemic toxicity RMS: Ireland Prochloraz 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is identical to the substance Prochloraz 266-994-5 67747-09-5 N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide Prochloraz C15H16Cl3N3O2 O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2 InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable Rat (as animal) Crj:CD(SD) 10 Male/Female intraperitoneal 6.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Ireland Prochloraz 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is identical to the substance Prochloraz 266-994-5 67747-09-5 N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide Prochloraz C15H16Cl3N3O2 O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2 InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3 organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Wistar 4 Male oral: gavage 4.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Ireland Prochloraz 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is identical to the substance Prochloraz 266-994-5 67747-09-5 N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide Prochloraz C15H16Cl3N3O2 O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2 InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3 organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Wistar 4 Male oral: gavage 14.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Ireland Prochloraz 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is identical to the substance Prochloraz 266-994-5 67747-09-5 N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide Prochloraz C15H16Cl3N3O2 O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2 InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3 organic compound Other Other chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) Yes Acceptable House mouse (as animal) CD-1 20 Male oral: feed 8.0000000000 week yes not applicable Negative RMS: Ireland Prochloraz 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is a metabolite of the substance 1-Propyl-1-[2-(2,4,6 trichlorophenoxy)ethyl]urea 1-Propyl-1-[2-(2,4,6-trichlorophenoxy)ethyl]urea Not in list C12H15Cl3N2O2 CCCN(CCOC1=C(C=C(C=C1Cl)Cl)Cl)C(=O)N InChI=1S/C12H15Cl3N2O2/c1-2-3-17(12(16)18)4-5-19-11-9(14)6-8(13)7-10(11)15/h6-7H,2-5H2,1H3,(H2,16,18) organometallic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Ireland Prochloraz 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is a metabolite of the substance 1-Propyl-1-[2-(2,4,6 trichlorophenoxy)ethyl]urea 1-Propyl-1-[2-(2,4,6-trichlorophenoxy)ethyl]urea Not in list C12H15Cl3N2O2 CCCN(CCOC1=C(C=C(C=C1Cl)Cl)Cl)C(=O)N InChI=1S/C12H15Cl3N2O2/c1-2-3-17(12(16)18)4-5-19-11-9(14)6-8(13)7-10(11)15/h6-7H,2-5H2,1H3,(H2,16,18) organometallic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Ireland Prochloraz 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is a metabolite of the substance 3-Formyl-1-propyl-1-[2-(2,4,6-trichlorophenoxy)ethyl]urea N-[propyl-[2-(2,4,6-trichlorophenoxy)ethyl]carbamoyl]formamide Not in list C13H15Cl3N2O3 CCCN(CCOC1=C(C=C(C=C1Cl)Cl)Cl)C(=O)NC=O InChI=1S/C13H15Cl3N2O3/c1-2-3-18(13(20)17-8-19)4-5-21-12-10(15)6-9(14)7-11(12)16/h6-8H,2-5H2,1H3,(H,17,19,20) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Ireland Prochloraz 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is a metabolite of the substance 3-Formyl-1-propyl-1-[2-(2,4,6-trichlorophenoxy)ethyl]urea N-[propyl-[2-(2,4,6-trichlorophenoxy)ethyl]carbamoyl]formamide Not in list C13H15Cl3N2O3 CCCN(CCOC1=C(C=C(C=C1Cl)Cl)Cl)C(=O)NC=O InChI=1S/C13H15Cl3N2O3/c1-2-3-18(13(20)17-8-19)4-5-21-12-10(15)6-9(14)7-11(12)16/h6-8H,2-5H2,1H3,(H,17,19,20) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Ireland Prochloraz 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is a metabolite of the substance 1-Propyl-1-[2-(2,4,6 trichlorophenoxy)ethyl]urea 1-Propyl-1-[2-(2,4,6-trichlorophenoxy)ethyl]urea Not in list C12H15Cl3N2O2 CCCN(CCOC1=C(C=C(C=C1Cl)Cl)Cl)C(=O)N InChI=1S/C12H15Cl3N2O2/c1-2-3-17(12(16)18)4-5-19-11-9(14)6-8(13)7-10(11)15/h6-7H,2-5H2,1H3,(H2,16,18) organometallic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Ireland Prochloraz 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is a metabolite of the substance 3-Formyl-1-propyl-1-[2-(2,4,6-trichlorophenoxy)ethyl]urea N-[propyl-[2-(2,4,6-trichlorophenoxy)ethyl]carbamoyl]formamide Not in list C13H15Cl3N2O3 CCCN(CCOC1=C(C=C(C=C1Cl)Cl)Cl)C(=O)NC=O InChI=1S/C13H15Cl3N2O3/c1-2-3-18(13(20)17-8-19)4-5-21-12-10(15)6-9(14)7-11(12)16/h6-8H,2-5H2,1H3,(H,17,19,20) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Ireland Prochloraz 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is a metabolite of the substance 1-Propyl-1-[2-(2,4,6 trichlorophenoxy)ethyl]urea 1-Propyl-1-[2-(2,4,6-trichlorophenoxy)ethyl]urea Not in list C12H15Cl3N2O2 CCCN(CCOC1=C(C=C(C=C1Cl)Cl)Cl)C(=O)N InChI=1S/C12H15Cl3N2O2/c1-2-3-17(12(16)18)4-5-19-11-9(14)6-8(13)7-10(11)15/h6-7H,2-5H2,1H3,(H2,16,18) organometallic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Ireland Prochloraz 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is a metabolite of the substance 3-Formyl-1-propyl-1-[2-(2,4,6-trichlorophenoxy)ethyl]urea N-[propyl-[2-(2,4,6-trichlorophenoxy)ethyl]carbamoyl]formamide Not in list C13H15Cl3N2O3 CCCN(CCOC1=C(C=C(C=C1Cl)Cl)Cl)C(=O)NC=O InChI=1S/C13H15Cl3N2O3/c1-2-3-18(13(20)17-8-19)4-5-21-12-10(15)6-9(14)7-11(12)16/h6-8H,2-5H2,1H3,(H,17,19,20) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Ireland Prochloraz 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is a metabolite of the substance 3-Formyl-1-propyl-1-[2-(2,4,6-trichlorophenoxy)ethyl]urea N-[propyl-[2-(2,4,6-trichlorophenoxy)ethyl]carbamoyl]formamide Not in list C13H15Cl3N2O3 CCCN(CCOC1=C(C=C(C=C1Cl)Cl)Cl)C(=O)NC=O InChI=1S/C13H15Cl3N2O3/c1-2-3-18(13(20)17-8-19)4-5-21-12-10(15)6-9(14)7-11(12)16/h6-8H,2-5H2,1H3,(H,17,19,20) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Ireland Prochloraz 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is a metabolite of the substance 1-Propyl-1-[2-(2,4,6 trichlorophenoxy)ethyl]urea 1-Propyl-1-[2-(2,4,6-trichlorophenoxy)ethyl]urea Not in list C12H15Cl3N2O2 CCCN(CCOC1=C(C=C(C=C1Cl)Cl)Cl)C(=O)N InChI=1S/C12H15Cl3N2O2/c1-2-3-17(12(16)18)4-5-19-11-9(14)6-8(13)7-10(11)15/h6-7H,2-5H2,1H3,(H2,16,18) organometallic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Ireland Prochloraz 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is a metabolite of the substance 3-Formyl-1-propyl-1-[2-(2,4,6-trichlorophenoxy)ethyl]urea N-[propyl-[2-(2,4,6-trichlorophenoxy)ethyl]carbamoyl]formamide Not in list C13H15Cl3N2O3 CCCN(CCOC1=C(C=C(C=C1Cl)Cl)Cl)C(=O)NC=O InChI=1S/C13H15Cl3N2O3/c1-2-3-18(13(20)17-8-19)4-5-21-12-10(15)6-9(14)7-11(12)16/h6-8H,2-5H2,1H3,(H,17,19,20) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Ireland Prochloraz 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is a metabolite of the substance 3-Formyl-1-propyl-1-[2-(2,4,6-trichlorophenoxy)ethyl]urea N-[propyl-[2-(2,4,6-trichlorophenoxy)ethyl]carbamoyl]formamide Not in list C13H15Cl3N2O3 CCCN(CCOC1=C(C=C(C=C1Cl)Cl)Cl)C(=O)NC=O InChI=1S/C13H15Cl3N2O3/c1-2-3-18(13(20)17-8-19)4-5-21-12-10(15)6-9(14)7-11(12)16/h6-8H,2-5H2,1H3,(H,17,19,20) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Ireland Prochloraz 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is a metabolite of the substance 1-Propyl-1-[2-(2,4,6 trichlorophenoxy)ethyl]urea 1-Propyl-1-[2-(2,4,6-trichlorophenoxy)ethyl]urea Not in list C12H15Cl3N2O2 CCCN(CCOC1=C(C=C(C=C1Cl)Cl)Cl)C(=O)N InChI=1S/C12H15Cl3N2O2/c1-2-3-17(12(16)18)4-5-19-11-9(14)6-8(13)7-10(11)15/h6-7H,2-5H2,1H3,(H2,16,18) organometallic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Ireland Prochloraz 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is a metabolite of the substance 1-Propyl-1-[2-(2,4,6 trichlorophenoxy)ethyl]urea 1-Propyl-1-[2-(2,4,6-trichlorophenoxy)ethyl]urea Not in list C12H15Cl3N2O2 CCCN(CCOC1=C(C=C(C=C1Cl)Cl)Cl)C(=O)N InChI=1S/C12H15Cl3N2O2/c1-2-3-17(12(16)18)4-5-19-11-9(14)6-8(13)7-10(11)15/h6-7H,2-5H2,1H3,(H2,16,18) organometallic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Ireland Prochloraz 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is a metabolite of the substance 3-Formyl-1-propyl-1-[2-(2,4,6-trichlorophenoxy)ethyl]urea N-[propyl-[2-(2,4,6-trichlorophenoxy)ethyl]carbamoyl]formamide Not in list C13H15Cl3N2O3 CCCN(CCOC1=C(C=C(C=C1Cl)Cl)Cl)C(=O)NC=O InChI=1S/C13H15Cl3N2O3/c1-2-3-18(13(20)17-8-19)4-5-21-12-10(15)6-9(14)7-11(12)16/h6-8H,2-5H2,1H3,(H,17,19,20) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Ireland Prochloraz 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is a metabolite of the substance 3-Formyl-1-propyl-1-[2-(2,4,6-trichlorophenoxy)ethyl]urea N-[propyl-[2-(2,4,6-trichlorophenoxy)ethyl]carbamoyl]formamide Not in list C13H15Cl3N2O3 CCCN(CCOC1=C(C=C(C=C1Cl)Cl)Cl)C(=O)NC=O InChI=1S/C13H15Cl3N2O3/c1-2-3-18(13(20)17-8-19)4-5-21-12-10(15)6-9(14)7-11(12)16/h6-8H,2-5H2,1H3,(H,17,19,20) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Ireland Prochloraz 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is a metabolite of the substance 3-Formyl-1-propyl-1-[2-(2,4,6-trichlorophenoxy)ethyl]urea N-[propyl-[2-(2,4,6-trichlorophenoxy)ethyl]carbamoyl]formamide Not in list C13H15Cl3N2O3 CCCN(CCOC1=C(C=C(C=C1Cl)Cl)Cl)C(=O)NC=O InChI=1S/C13H15Cl3N2O3/c1-2-3-18(13(20)17-8-19)4-5-21-12-10(15)6-9(14)7-11(12)16/h6-8H,2-5H2,1H3,(H,17,19,20) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Ireland Prochloraz 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is a metabolite of the substance 1-Propyl-1-[2-(2,4,6 trichlorophenoxy)ethyl]urea 1-Propyl-1-[2-(2,4,6-trichlorophenoxy)ethyl]urea Not in list C12H15Cl3N2O2 CCCN(CCOC1=C(C=C(C=C1Cl)Cl)Cl)C(=O)N InChI=1S/C12H15Cl3N2O2/c1-2-3-17(12(16)18)4-5-19-11-9(14)6-8(13)7-10(11)15/h6-7H,2-5H2,1H3,(H2,16,18) organometallic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Ireland Prochloraz 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is a metabolite of the substance 1-Propyl-1-[2-(2,4,6 trichlorophenoxy)ethyl]urea 1-Propyl-1-[2-(2,4,6-trichlorophenoxy)ethyl]urea Not in list C12H15Cl3N2O2 CCCN(CCOC1=C(C=C(C=C1Cl)Cl)Cl)C(=O)N InChI=1S/C12H15Cl3N2O2/c1-2-3-17(12(16)18)4-5-19-11-9(14)6-8(13)7-10(11)15/h6-7H,2-5H2,1H3,(H2,16,18) organometallic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Ireland Prochloraz 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is a metabolite of the substance 1-Propyl-1-[2-(2,4,6 trichlorophenoxy)ethyl]urea 1-Propyl-1-[2-(2,4,6-trichlorophenoxy)ethyl]urea Not in list C12H15Cl3N2O2 CCCN(CCOC1=C(C=C(C=C1Cl)Cl)Cl)C(=O)N InChI=1S/C12H15Cl3N2O2/c1-2-3-17(12(16)18)4-5-19-11-9(14)6-8(13)7-10(11)15/h6-7H,2-5H2,1H3,(H2,16,18) organometallic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Ireland Prochloraz 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is identical to the substance Prochloraz 266-994-5 67747-09-5 N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide Prochloraz C15H16Cl3N3O2 O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2 InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Ireland Prochloraz (Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is identical to the substance Prochloraz 266-994-5 67747-09-5 N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide Prochloraz C15H16Cl3N3O2 O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2 InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Ireland Prochloraz (Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is identical to the substance Prochloraz 266-994-5 67747-09-5 N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide Prochloraz C15H16Cl3N3O2 O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2 InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Ireland Prochloraz (Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is identical to the substance Prochloraz 266-994-5 67747-09-5 N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide Prochloraz C15H16Cl3N3O2 O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2 InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Ireland Prochloraz (Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is identical to the substance Prochloraz 266-994-5 67747-09-5 N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide Prochloraz C15H16Cl3N3O2 O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2 InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: Ireland Prochloraz (Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is identical to the substance Prochloraz 266-994-5 67747-09-5 N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide Prochloraz C15H16Cl3N3O2 O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2 InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Ireland Prochloraz (Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is identical to the substance Prochloraz 266-994-5 67747-09-5 N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide Prochloraz C15H16Cl3N3O2 O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2 InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Ireland Prochloraz (Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is identical to the substance Prochloraz 266-994-5 67747-09-5 N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide Prochloraz C15H16Cl3N3O2 O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2 InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: Ireland Prochloraz (Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is identical to the substance Prochloraz 266-994-5 67747-09-5 N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide Prochloraz C15H16Cl3N3O2 O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2 InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Ireland Prochloraz (Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is identical to the substance Prochloraz 266-994-5 67747-09-5 N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide Prochloraz C15H16Cl3N3O2 O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2 InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Ireland Prochloraz (Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is identical to the substance Prochloraz 266-994-5 67747-09-5 N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide Prochloraz C15H16Cl3N3O2 O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2 InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Ireland Prochloraz (Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is identical to the substance Prochloraz 266-994-5 67747-09-5 N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide Prochloraz C15H16Cl3N3O2 O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2 InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Ireland Prochloraz (Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is identical to the substance Prochloraz 266-994-5 67747-09-5 N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide Prochloraz C15H16Cl3N3O2 O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2 InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Ireland Prochloraz (Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is identical to the substance Prochloraz 266-994-5 67747-09-5 N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide Prochloraz C15H16Cl3N3O2 O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2 InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Ireland Prochloraz (Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is identical to the substance Prochloraz 266-994-5 67747-09-5 N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide Prochloraz C15H16Cl3N3O2 O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2 InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Ireland Prochloraz (Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is identical to the substance Prochloraz 266-994-5 67747-09-5 N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide Prochloraz C15H16Cl3N3O2 O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2 InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Ireland Prochloraz (Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is identical to the substance Prochloraz 266-994-5 67747-09-5 N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide Prochloraz C15H16Cl3N3O2 O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2 InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Ireland Prochloraz (Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is identical to the substance Prochloraz 266-994-5 67747-09-5 N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide Prochloraz C15H16Cl3N3O2 O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2 InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Ireland Prochloraz (Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is identical to the substance Prochloraz 266-994-5 67747-09-5 N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide Prochloraz C15H16Cl3N3O2 O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2 InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported no data with Negative RMS: Ireland Prochloraz (Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is identical to the substance Prochloraz 266-994-5 67747-09-5 N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide Prochloraz C15H16Cl3N3O2 O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2 InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Ireland Prochloraz (Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is identical to the substance Prochloraz 266-994-5 67747-09-5 N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide Prochloraz C15H16Cl3N3O2 O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2 InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported no data without Negative RMS: Ireland Prochloraz (Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is identical to the substance Prochloraz 266-994-5 67747-09-5 N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide Prochloraz C15H16Cl3N3O2 O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2 InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Ireland Prochloraz (Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is identical to the substance Prochloraz 266-994-5 67747-09-5 N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide Prochloraz C15H16Cl3N3O2 O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2 InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No data Acceptable Human (as organism) lymphocytes Not reported no data without Negative RMS: Ireland Prochloraz (Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is identical to the substance Prochloraz 266-994-5 67747-09-5 N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide Prochloraz C15H16Cl3N3O2 O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2 InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No data Acceptable Human (as organism) lymphocytes Not reported no data with Positive RMS: Ireland Prochloraz (Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is identical to the substance Prochloraz 266-994-5 67747-09-5 N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide Prochloraz C15H16Cl3N3O2 O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2 InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3 organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo Equivalent or similar to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No data Acceptable Rat (as animal) Crj:CD(SD) Male oral: unspecified no data not applicable Negative RMS: Ireland Prochloraz (Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Prochloraz 266-994-5 67747-09-5 single chemical entity Component is identical to the substance Prochloraz 266-994-5 67747-09-5 N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide Prochloraz C15H16Cl3N3O2 O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2 InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable House mouse (as animal) CD-1 Male/Female oral: unspecified no data not applicable Negative no evidence RMS: Ireland Prochloraz (Addendum) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz 22Jul2011 2011 doi:10.2903/j.efsa.2011.2323
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is identical to the substance Pirimicarb 245-430-1 23103-98-2 [2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate Pirimicarb C11H18N4O2 CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is identical to the substance Pirimicarb 245-430-1 23103-98-2 [2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate Pirimicarb C11H18N4O2 CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is identical to the substance Pirimicarb 245-430-1 23103-98-2 [2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate Pirimicarb C11H18N4O2 CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is identical to the substance Pirimicarb 245-430-1 23103-98-2 [2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate Pirimicarb C11H18N4O2 CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is identical to the substance Pirimicarb 245-430-1 23103-98-2 [2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate Pirimicarb C11H18N4O2 CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is identical to the substance Pirimicarb 245-430-1 23103-98-2 [2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate Pirimicarb C11H18N4O2 CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is identical to the substance Pirimicarb 245-430-1 23103-98-2 [2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate Pirimicarb C11H18N4O2 CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes with Negative RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is identical to the substance Pirimicarb 245-430-1 23103-98-2 [2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate Pirimicarb C11H18N4O2 CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is identical to the substance Pirimicarb 245-430-1 23103-98-2 [2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate Pirimicarb C11H18N4O2 CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is identical to the substance Pirimicarb 245-430-1 23103-98-2 [2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate Pirimicarb C11H18N4O2 CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is identical to the substance Pirimicarb 245-430-1 23103-98-2 [2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate Pirimicarb C11H18N4O2 CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes without Negative RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is identical to the substance Pirimicarb 245-430-1 23103-98-2 [2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate Pirimicarb C11H18N4O2 CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is identical to the substance Pirimicarb 245-430-1 23103-98-2 [2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate Pirimicarb C11H18N4O2 CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is identical to the substance Pirimicarb 245-430-1 23103-98-2 [2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate Pirimicarb C11H18N4O2 CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is identical to the substance Pirimicarb 245-430-1 23103-98-2 [2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate Pirimicarb C11H18N4O2 CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is identical to the substance Pirimicarb 245-430-1 23103-98-2 [2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate Pirimicarb C11H18N4O2 CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is identical to the substance Pirimicarb 245-430-1 23103-98-2 [2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate Pirimicarb C11H18N4O2 CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is identical to the substance Pirimicarb 245-430-1 23103-98-2 [2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate Pirimicarb C11H18N4O2 CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is identical to the substance Pirimicarb 245-430-1 23103-98-2 [2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate Pirimicarb C11H18N4O2 CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is identical to the substance Pirimicarb 245-430-1 23103-98-2 [2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate Pirimicarb C11H18N4O2 CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is identical to the substance Pirimicarb 245-430-1 23103-98-2 [2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate Pirimicarb C11H18N4O2 CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is identical to the substance Pirimicarb 245-430-1 23103-98-2 [2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate Pirimicarb C11H18N4O2 CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is identical to the substance Pirimicarb 245-430-1 23103-98-2 [2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate Pirimicarb C11H18N4O2 CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative small colonies RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is identical to the substance Pirimicarb 245-430-1 23103-98-2 [2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate Pirimicarb C11H18N4O2 CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Positive large colonies RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is identical to the substance Pirimicarb 245-430-1 23103-98-2 [2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate Pirimicarb C11H18N4O2 CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative large colonies RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is identical to the substance Pirimicarb 245-430-1 23103-98-2 [2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate Pirimicarb C11H18N4O2 CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Positive small colonies RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is identical to the substance Pirimicarb 245-430-1 23103-98-2 [2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate Pirimicarb C11H18N4O2 CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No data Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is identical to the substance Pirimicarb 245-430-1 23103-98-2 [2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate Pirimicarb C11H18N4O2 CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No data Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is identical to the substance Pirimicarb 245-430-1 23103-98-2 [2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate Pirimicarb C11H18N4O2 CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable House mouse (as animal) C57BL 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is identical to the substance Pirimicarb 245-430-1 23103-98-2 [2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate Pirimicarb C11H18N4O2 CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable House mouse (as animal) C57BL 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is identical to the substance Pirimicarb 245-430-1 23103-98-2 [2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate Pirimicarb C11H18N4O2 CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable House mouse (as animal) C57BL 10 Male/Female oral: gavage 72.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is identical to the substance Pirimicarb 245-430-1 23103-98-2 [2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate Pirimicarb C11H18N4O2 CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo Equivalent or similar to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No data Acceptable Rat (as animal) Alpk:APf SD Rat 10 Male oral: unspecified 4.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is identical to the substance Pirimicarb 245-430-1 23103-98-2 [2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate Pirimicarb C11H18N4O2 CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo Equivalent or similar to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No data Acceptable Rat (as animal) Alpk:APf SD Rat 10 Male oral: unspecified 16.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is identical to the substance Pirimicarb 245-430-1 23103-98-2 [2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate Pirimicarb C11H18N4O2 CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) Yes Acceptable House mouse (as animal) CD-1 15 Male oral: gavage 5.0000000000 D yes not applicable Negative RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is a metabolite of the substance 5,6-dimethyl-2-(methylamino)pyrimidin-4-ol 5,6-dimethyl-2-(methylamino)pyrimidin-4-ol Not in list C7H11N3O Cc1nc(NC)nc(O)c1C InChI=1S/C7H11N3O/c1-4-5(2)9-7(8-3)10-6(4)11/h1-3H3,(H2,8,9,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is a metabolite of the substance 5,6-dimethyl-2-(methylamino)pyrimidin-4-ol 5,6-dimethyl-2-(methylamino)pyrimidin-4-ol Not in list C7H11N3O Cc1nc(NC)nc(O)c1C InChI=1S/C7H11N3O/c1-4-5(2)9-7(8-3)10-6(4)11/h1-3H3,(H2,8,9,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is a metabolite of the substance 5,6-dimethyl-2-(methylamino)pyrimidin-4-ol 5,6-dimethyl-2-(methylamino)pyrimidin-4-ol Not in list C7H11N3O Cc1nc(NC)nc(O)c1C InChI=1S/C7H11N3O/c1-4-5(2)9-7(8-3)10-6(4)11/h1-3H3,(H2,8,9,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes without Negative RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is a metabolite of the substance 5,6-dimethyl-2-(methylamino)pyrimidin-4-ol 5,6-dimethyl-2-(methylamino)pyrimidin-4-ol Not in list C7H11N3O Cc1nc(NC)nc(O)c1C InChI=1S/C7H11N3O/c1-4-5(2)9-7(8-3)10-6(4)11/h1-3H3,(H2,8,9,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is a metabolite of the substance 5,6-dimethyl-2-(methylamino)pyrimidin-4-ol 5,6-dimethyl-2-(methylamino)pyrimidin-4-ol Not in list C7H11N3O Cc1nc(NC)nc(O)c1C InChI=1S/C7H11N3O/c1-4-5(2)9-7(8-3)10-6(4)11/h1-3H3,(H2,8,9,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is a metabolite of the substance 5,6-dimethyl-2-(methylamino)pyrimidin-4-ol 5,6-dimethyl-2-(methylamino)pyrimidin-4-ol Not in list C7H11N3O Cc1nc(NC)nc(O)c1C InChI=1S/C7H11N3O/c1-4-5(2)9-7(8-3)10-6(4)11/h1-3H3,(H2,8,9,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is a metabolite of the substance 5,6-dimethyl-2-(methylamino)pyrimidin-4-ol 5,6-dimethyl-2-(methylamino)pyrimidin-4-ol Not in list C7H11N3O Cc1nc(NC)nc(O)c1C InChI=1S/C7H11N3O/c1-4-5(2)9-7(8-3)10-6(4)11/h1-3H3,(H2,8,9,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is a metabolite of the substance 5,6-dimethyl-2-(methylamino)pyrimidin-4-ol 5,6-dimethyl-2-(methylamino)pyrimidin-4-ol Not in list C7H11N3O Cc1nc(NC)nc(O)c1C InChI=1S/C7H11N3O/c1-4-5(2)9-7(8-3)10-6(4)11/h1-3H3,(H2,8,9,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is a metabolite of the substance 5,6-dimethyl-2-(methylamino)pyrimidin-4-ol 5,6-dimethyl-2-(methylamino)pyrimidin-4-ol Not in list C7H11N3O Cc1nc(NC)nc(O)c1C InChI=1S/C7H11N3O/c1-4-5(2)9-7(8-3)10-6(4)11/h1-3H3,(H2,8,9,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes with Negative RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is a metabolite of the substance 5,6-dimethyl-2-(methylamino)pyrimidin-4-ol 5,6-dimethyl-2-(methylamino)pyrimidin-4-ol Not in list C7H11N3O Cc1nc(NC)nc(O)c1C InChI=1S/C7H11N3O/c1-4-5(2)9-7(8-3)10-6(4)11/h1-3H3,(H2,8,9,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is a metabolite of the substance 5,6-dimethyl-2-(methylamino)pyrimidin-4-ol 5,6-dimethyl-2-(methylamino)pyrimidin-4-ol Not in list C7H11N3O Cc1nc(NC)nc(O)c1C InChI=1S/C7H11N3O/c1-4-5(2)9-7(8-3)10-6(4)11/h1-3H3,(H2,8,9,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is a metabolite of the substance 5,6-dimethyl-2-(methylamino)pyrimidin-4-ol 5,6-dimethyl-2-(methylamino)pyrimidin-4-ol Not in list C7H11N3O Cc1nc(NC)nc(O)c1C InChI=1S/C7H11N3O/c1-4-5(2)9-7(8-3)10-6(4)11/h1-3H3,(H2,8,9,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is a metabolite of the substance 5,6-dimethyl-2-(methylamino)pyrimidin-4-ol 5,6-dimethyl-2-(methylamino)pyrimidin-4-ol Not in list C7H11N3O Cc1nc(NC)nc(O)c1C InChI=1S/C7H11N3O/c1-4-5(2)9-7(8-3)10-6(4)11/h1-3H3,(H2,8,9,10,11) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Positive large colonies RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is a metabolite of the substance 5,6-dimethyl-2-(methylamino)pyrimidin-4-ol 5,6-dimethyl-2-(methylamino)pyrimidin-4-ol Not in list C7H11N3O Cc1nc(NC)nc(O)c1C InChI=1S/C7H11N3O/c1-4-5(2)9-7(8-3)10-6(4)11/h1-3H3,(H2,8,9,10,11) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative small colonies RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is a metabolite of the substance 5,6-dimethyl-2-(methylamino)pyrimidin-4-ol 5,6-dimethyl-2-(methylamino)pyrimidin-4-ol Not in list C7H11N3O Cc1nc(NC)nc(O)c1C InChI=1S/C7H11N3O/c1-4-5(2)9-7(8-3)10-6(4)11/h1-3H3,(H2,8,9,10,11) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative large colonies RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is a metabolite of the substance 5,6-dimethyl-2-(methylamino)pyrimidin-4-ol 5,6-dimethyl-2-(methylamino)pyrimidin-4-ol Not in list C7H11N3O Cc1nc(NC)nc(O)c1C InChI=1S/C7H11N3O/c1-4-5(2)9-7(8-3)10-6(4)11/h1-3H3,(H2,8,9,10,11) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Positive small colonies RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is a metabolite of the substance 5,6-dimethyl-2-(methylamino)pyrimidin-4-ol 5,6-dimethyl-2-(methylamino)pyrimidin-4-ol Not in list C7H11N3O Cc1nc(NC)nc(O)c1C InChI=1S/C7H11N3O/c1-4-5(2)9-7(8-3)10-6(4)11/h1-3H3,(H2,8,9,10,11) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes without Negative RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is a metabolite of the substance 5,6-dimethyl-2-(methylamino)pyrimidin-4-ol 5,6-dimethyl-2-(methylamino)pyrimidin-4-ol Not in list C7H11N3O Cc1nc(NC)nc(O)c1C InChI=1S/C7H11N3O/c1-4-5(2)9-7(8-3)10-6(4)11/h1-3H3,(H2,8,9,10,11) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes with Negative RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is a metabolite of the substance 2-dimethylamino-5,6-dimethylpyrimidin-4-ol 2-(dimethylamino)-5,6-dimethylpyrimidin-4-ol Not in list C8H13N3O Cc1nc(nc(O)c1C)N(C)C InChI=1S/C8H13N3O/c1-5-6(2)9-8(11(3)4)10-7(5)12/h1-4H3,(H,9,10,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes with Negative RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is a metabolite of the substance 2-dimethylamino-5,6-dimethylpyrimidin-4-ol 2-(dimethylamino)-5,6-dimethylpyrimidin-4-ol Not in list C8H13N3O Cc1nc(nc(O)c1C)N(C)C InChI=1S/C8H13N3O/c1-5-6(2)9-8(11(3)4)10-7(5)12/h1-4H3,(H,9,10,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes without Negative RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is a metabolite of the substance 2-dimethylamino-5,6-dimethylpyrimidin-4-ol 2-(dimethylamino)-5,6-dimethylpyrimidin-4-ol Not in list C8H13N3O Cc1nc(nc(O)c1C)N(C)C InChI=1S/C8H13N3O/c1-5-6(2)9-8(11(3)4)10-7(5)12/h1-4H3,(H,9,10,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is a metabolite of the substance 2-dimethylamino-5,6-dimethylpyrimidin-4-ol 2-(dimethylamino)-5,6-dimethylpyrimidin-4-ol Not in list C8H13N3O Cc1nc(nc(O)c1C)N(C)C InChI=1S/C8H13N3O/c1-5-6(2)9-8(11(3)4)10-7(5)12/h1-4H3,(H,9,10,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is a metabolite of the substance 2-dimethylamino-5,6-dimethylpyrimidin-4-ol 2-(dimethylamino)-5,6-dimethylpyrimidin-4-ol Not in list C8H13N3O Cc1nc(nc(O)c1C)N(C)C InChI=1S/C8H13N3O/c1-5-6(2)9-8(11(3)4)10-7(5)12/h1-4H3,(H,9,10,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is a metabolite of the substance 2-dimethylamino-5,6-dimethylpyrimidin-4-ol 2-(dimethylamino)-5,6-dimethylpyrimidin-4-ol Not in list C8H13N3O Cc1nc(nc(O)c1C)N(C)C InChI=1S/C8H13N3O/c1-5-6(2)9-8(11(3)4)10-7(5)12/h1-4H3,(H,9,10,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is a metabolite of the substance 2-dimethylamino-5,6-dimethylpyrimidin-4-ol 2-(dimethylamino)-5,6-dimethylpyrimidin-4-ol Not in list C8H13N3O Cc1nc(nc(O)c1C)N(C)C InChI=1S/C8H13N3O/c1-5-6(2)9-8(11(3)4)10-7(5)12/h1-4H3,(H,9,10,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is a metabolite of the substance 2-dimethylamino-5,6-dimethylpyrimidin-4-ol 2-(dimethylamino)-5,6-dimethylpyrimidin-4-ol Not in list C8H13N3O Cc1nc(nc(O)c1C)N(C)C InChI=1S/C8H13N3O/c1-5-6(2)9-8(11(3)4)10-7(5)12/h1-4H3,(H,9,10,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is a metabolite of the substance 2-dimethylamino-5,6-dimethylpyrimidin-4-ol 2-(dimethylamino)-5,6-dimethylpyrimidin-4-ol Not in list C8H13N3O Cc1nc(nc(O)c1C)N(C)C InChI=1S/C8H13N3O/c1-5-6(2)9-8(11(3)4)10-7(5)12/h1-4H3,(H,9,10,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is a metabolite of the substance 2-dimethylamino-5,6-dimethylpyrimidin-4-ol 2-(dimethylamino)-5,6-dimethylpyrimidin-4-ol Not in list C8H13N3O Cc1nc(nc(O)c1C)N(C)C InChI=1S/C8H13N3O/c1-5-6(2)9-8(11(3)4)10-7(5)12/h1-4H3,(H,9,10,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is a metabolite of the substance 2-dimethylamino-5,6-dimethylpyrimidin-4-ol 2-(dimethylamino)-5,6-dimethylpyrimidin-4-ol Not in list C8H13N3O Cc1nc(nc(O)c1C)N(C)C InChI=1S/C8H13N3O/c1-5-6(2)9-8(11(3)4)10-7(5)12/h1-4H3,(H,9,10,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is a metabolite of the substance 2-dimethylamino-5,6-dimethylpyrimidin-4-ol 2-(dimethylamino)-5,6-dimethylpyrimidin-4-ol Not in list C8H13N3O Cc1nc(nc(O)c1C)N(C)C InChI=1S/C8H13N3O/c1-5-6(2)9-8(11(3)4)10-7(5)12/h1-4H3,(H,9,10,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is a metabolite of the substance 2-dimethylamino-5,6-dimethylpyrimidin-4-ol 2-(dimethylamino)-5,6-dimethylpyrimidin-4-ol Not in list C8H13N3O Cc1nc(nc(O)c1C)N(C)C InChI=1S/C8H13N3O/c1-5-6(2)9-8(11(3)4)10-7(5)12/h1-4H3,(H,9,10,12) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Positive small colonies RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is a metabolite of the substance 2-dimethylamino-5,6-dimethylpyrimidin-4-ol 2-(dimethylamino)-5,6-dimethylpyrimidin-4-ol Not in list C8H13N3O Cc1nc(nc(O)c1C)N(C)C InChI=1S/C8H13N3O/c1-5-6(2)9-8(11(3)4)10-7(5)12/h1-4H3,(H,9,10,12) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Positive small colonies RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is a metabolite of the substance 2-dimethylamino-5,6-dimethylpyrimidin-4-ol 2-(dimethylamino)-5,6-dimethylpyrimidin-4-ol Not in list C8H13N3O Cc1nc(nc(O)c1C)N(C)C InChI=1S/C8H13N3O/c1-5-6(2)9-8(11(3)4)10-7(5)12/h1-4H3,(H,9,10,12) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Positive large colonies RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is a metabolite of the substance 2-dimethylamino-5,6-dimethylpyrimidin-4-ol 2-(dimethylamino)-5,6-dimethylpyrimidin-4-ol Not in list C8H13N3O Cc1nc(nc(O)c1C)N(C)C InChI=1S/C8H13N3O/c1-5-6(2)9-8(11(3)4)10-7(5)12/h1-4H3,(H,9,10,12) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Positive large colonies RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is a metabolite of the substance 2-dimethylamino-5,6-dimethylpyrimidin-4-ol 2-(dimethylamino)-5,6-dimethylpyrimidin-4-ol Not in list C8H13N3O Cc1nc(nc(O)c1C)N(C)C InChI=1S/C8H13N3O/c1-5-6(2)9-8(11(3)4)10-7(5)12/h1-4H3,(H,9,10,12) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Positive RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is a metabolite of the substance 2-dimethylamino-5,6-dimethylpyrimidin-4-ol 2-(dimethylamino)-5,6-dimethylpyrimidin-4-ol Not in list C8H13N3O Cc1nc(nc(O)c1C)N(C)C InChI=1S/C8H13N3O/c1-5-6(2)9-8(11(3)4)10-7(5)12/h1-4H3,(H,9,10,12) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Positive RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is a metabolite of the substance 2-dimethylamino-5,6-dimethylpyrimidin-4-ol 2-(dimethylamino)-5,6-dimethylpyrimidin-4-ol Not in list C8H13N3O Cc1nc(nc(O)c1C)N(C)C InChI=1S/C8H13N3O/c1-5-6(2)9-8(11(3)4)10-7(5)12/h1-4H3,(H,9,10,12) organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Alpk:APf SD Rat 6 Male/Female oral: gavage 16.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is a metabolite of the substance 2-dimethylamino-5,6-dimethylpyrimidin-4-ol 2-(dimethylamino)-5,6-dimethylpyrimidin-4-ol Not in list C8H13N3O Cc1nc(nc(O)c1C)N(C)C InChI=1S/C8H13N3O/c1-5-6(2)9-8(11(3)4)10-7(5)12/h1-4H3,(H,9,10,12) organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Alpk:APf SD Rat 6 Male/Female oral: gavage 2.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is a metabolite of the substance 2-dimethylamino-5,6-dimethylpyrimidin-4-ol 2-(dimethylamino)-5,6-dimethylpyrimidin-4-ol Not in list C8H13N3O Cc1nc(nc(O)c1C)N(C)C InChI=1S/C8H13N3O/c1-5-6(2)9-8(11(3)4)10-7(5)12/h1-4H3,(H,9,10,12) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 5 Male oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimicarb 245-430-1 23103-98-2 single chemical entity Component is a metabolite of the substance 2-dimethylamino-5,6-dimethylpyrimidin-4-ol 2-(dimethylamino)-5,6-dimethylpyrimidin-4-ol Not in list C8H13N3O Cc1nc(nc(O)c1C)N(C)C InChI=1S/C8H13N3O/c1-5-6(2)9-8(11(3)4)10-7(5)12/h1-4H3,(H,9,10,12) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 5 Male oral: unspecified 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The United Kingdom Pirimicarb 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb 31Aug2005 2005 doi:10.2903/j.efsa.2005.43r
+Pirimiphos-methyl 249-528-5 29232-93-7 single chemical entity Component is identical to the substance Pirimiphos-methyl 249-528-5 29232-93-7 O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate Pirimiphos-methyl C11H20N3O3PS CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1 InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Pirimiphos-methyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl 31Aug2005 2005 doi:10.2903/j.efsa.2005.44r
+Pirimiphos-methyl 249-528-5 29232-93-7 single chemical entity Component is identical to the substance Pirimiphos-methyl 249-528-5 29232-93-7 O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate Pirimiphos-methyl C11H20N3O3PS CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1 InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Pirimiphos-methyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl 31Aug2005 2005 doi:10.2903/j.efsa.2005.44r
+Pirimiphos-methyl 249-528-5 29232-93-7 single chemical entity Component is identical to the substance Pirimiphos-methyl 249-528-5 29232-93-7 O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate Pirimiphos-methyl C11H20N3O3PS CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1 InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Pirimiphos-methyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl 31Aug2005 2005 doi:10.2903/j.efsa.2005.44r
+Pirimiphos-methyl 249-528-5 29232-93-7 single chemical entity Component is identical to the substance Pirimiphos-methyl 249-528-5 29232-93-7 O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate Pirimiphos-methyl C11H20N3O3PS CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1 InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Pirimiphos-methyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl 31Aug2005 2005 doi:10.2903/j.efsa.2005.44r
+Pirimiphos-methyl 249-528-5 29232-93-7 single chemical entity Component is identical to the substance Pirimiphos-methyl 249-528-5 29232-93-7 O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate Pirimiphos-methyl C11H20N3O3PS CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1 InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Pirimiphos-methyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl 31Aug2005 2005 doi:10.2903/j.efsa.2005.44r
+Pirimiphos-methyl 249-528-5 29232-93-7 single chemical entity Component is identical to the substance Pirimiphos-methyl 249-528-5 29232-93-7 O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate Pirimiphos-methyl C11H20N3O3PS CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1 InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Pirimiphos-methyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl 31Aug2005 2005 doi:10.2903/j.efsa.2005.44r
+Pirimiphos-methyl 249-528-5 29232-93-7 single chemical entity Component is identical to the substance Pirimiphos-methyl 249-528-5 29232-93-7 O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate Pirimiphos-methyl C11H20N3O3PS CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1 InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Pirimiphos-methyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl 31Aug2005 2005 doi:10.2903/j.efsa.2005.44r
+Pirimiphos-methyl 249-528-5 29232-93-7 single chemical entity Component is identical to the substance Pirimiphos-methyl 249-528-5 29232-93-7 O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate Pirimiphos-methyl C11H20N3O3PS CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1 InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Pirimiphos-methyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl 31Aug2005 2005 doi:10.2903/j.efsa.2005.44r
+Pirimiphos-methyl 249-528-5 29232-93-7 single chemical entity Component is identical to the substance Pirimiphos-methyl 249-528-5 29232-93-7 O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate Pirimiphos-methyl C11H20N3O3PS CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1 InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Pirimiphos-methyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl 31Aug2005 2005 doi:10.2903/j.efsa.2005.44r
+Pirimiphos-methyl 249-528-5 29232-93-7 single chemical entity Component is identical to the substance Pirimiphos-methyl 249-528-5 29232-93-7 O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate Pirimiphos-methyl C11H20N3O3PS CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1 InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Pirimiphos-methyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl 31Aug2005 2005 doi:10.2903/j.efsa.2005.44r
+Pirimiphos-methyl 249-528-5 29232-93-7 single chemical entity Component is identical to the substance Pirimiphos-methyl 249-528-5 29232-93-7 O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate Pirimiphos-methyl C11H20N3O3PS CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1 InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative no information RMS: The United Kingdom Pirimiphos-methyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl 31Aug2005 2005 doi:10.2903/j.efsa.2005.44r
+Pirimiphos-methyl 249-528-5 29232-93-7 single chemical entity Component is identical to the substance Pirimiphos-methyl 249-528-5 29232-93-7 O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate Pirimiphos-methyl C11H20N3O3PS CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1 InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Negative no information RMS: The United Kingdom Pirimiphos-methyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl 31Aug2005 2005 doi:10.2903/j.efsa.2005.44r
+Pirimiphos-methyl 249-528-5 29232-93-7 single chemical entity Component is identical to the substance Pirimiphos-methyl 249-528-5 29232-93-7 O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate Pirimiphos-methyl C11H20N3O3PS CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1 InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes without Negative RMS: The United Kingdom Pirimiphos-methyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl 31Aug2005 2005 doi:10.2903/j.efsa.2005.44r
+Pirimiphos-methyl 249-528-5 29232-93-7 single chemical entity Component is identical to the substance Pirimiphos-methyl 249-528-5 29232-93-7 O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate Pirimiphos-methyl C11H20N3O3PS CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1 InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes with Negative RMS: The United Kingdom Pirimiphos-methyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl 31Aug2005 2005 doi:10.2903/j.efsa.2005.44r
+Pirimiphos-methyl 249-528-5 29232-93-7 single chemical entity Component is identical to the substance Pirimiphos-methyl 249-528-5 29232-93-7 O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate Pirimiphos-methyl C11H20N3O3PS CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1 InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3 organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro According to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No Acceptable Hamster (as animal) fibroblast Not reported yes with Ambiguous RMS: The United Kingdom Pirimiphos-methyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl 31Aug2005 2005 doi:10.2903/j.efsa.2005.44r
+Pirimiphos-methyl 249-528-5 29232-93-7 single chemical entity Component is identical to the substance Pirimiphos-methyl 249-528-5 29232-93-7 O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate Pirimiphos-methyl C11H20N3O3PS CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1 InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3 organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro According to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No Acceptable Hamster (as animal) fibroblast Not reported yes without Ambiguous RMS: The United Kingdom Pirimiphos-methyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl 31Aug2005 2005 doi:10.2903/j.efsa.2005.44r
+Pirimiphos-methyl 249-528-5 29232-93-7 single chemical entity Component is identical to the substance Pirimiphos-methyl 249-528-5 29232-93-7 O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate Pirimiphos-methyl C11H20N3O3PS CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1 InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3 organic compound Other Other DNA damage and/or repair in vitro mammalian cell transformation assay in vitro No guideline available Not reported Not applicable Acceptable Hamster (as animal) fibroblast Not reported yes with Positive RMS: The United Kingdom Pirimiphos-methyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl 31Aug2005 2005 doi:10.2903/j.efsa.2005.44r
+Pirimiphos-methyl 249-528-5 29232-93-7 single chemical entity Component is identical to the substance Pirimiphos-methyl 249-528-5 29232-93-7 O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate Pirimiphos-methyl C11H20N3O3PS CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1 InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3 organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Alpk:APf SD Rat 5 Male oral: gavage 16.0000000000 h no data not applicable Negative RMS: The United Kingdom Pirimiphos-methyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl 31Aug2005 2005 doi:10.2903/j.efsa.2005.44r
+Pirimiphos-methyl 249-528-5 29232-93-7 single chemical entity Component is identical to the substance Pirimiphos-methyl 249-528-5 29232-93-7 O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate Pirimiphos-methyl C11H20N3O3PS CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1 InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3 organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Alpk:APf SD Rat 5 Male oral: gavage 2.0000000000 h no data not applicable Negative RMS: The United Kingdom Pirimiphos-methyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl 31Aug2005 2005 doi:10.2903/j.efsa.2005.44r
+Pirimiphos-methyl 249-528-5 29232-93-7 single chemical entity Component is identical to the substance Pirimiphos-methyl 249-528-5 29232-93-7 O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate Pirimiphos-methyl C11H20N3O3PS CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1 InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3 organic compound Other Other chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) No data Acceptable House mouse (as animal) CD-1 15 Male oral: gavage 5.0000000000 D yes not applicable Negative RMS: The United Kingdom Pirimiphos-methyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl 31Aug2005 2005 doi:10.2903/j.efsa.2005.44r
+Pirimiphos-methyl 249-528-5 29232-93-7 single chemical entity Component is identical to the substance Pirimiphos-methyl 249-528-5 29232-93-7 O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate Pirimiphos-methyl C11H20N3O3PS CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1 InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: The United Kingdom Pirimiphos-methyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl 31Aug2005 2005 doi:10.2903/j.efsa.2005.44r
+Pirimiphos-methyl 249-528-5 29232-93-7 single chemical entity Component is identical to the substance Pirimiphos-methyl 249-528-5 29232-93-7 O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate Pirimiphos-methyl C11H20N3O3PS CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1 InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Positive RMS: The United Kingdom Pirimiphos-methyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl 31Aug2005 2005 doi:10.2903/j.efsa.2005.44r
+Pirimiphos-methyl 249-528-5 29232-93-7 single chemical entity Component is identical to the substance Pirimiphos-methyl 249-528-5 29232-93-7 O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate Pirimiphos-methyl C11H20N3O3PS CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1 InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The United Kingdom Pirimiphos-methyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl 31Aug2005 2005 doi:10.2903/j.efsa.2005.44r
+Pirimiphos-methyl 249-528-5 29232-93-7 single chemical entity Component is identical to the substance Pirimiphos-methyl 249-528-5 29232-93-7 O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate Pirimiphos-methyl C11H20N3O3PS CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1 InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: The United Kingdom Pirimiphos-methyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl 31Aug2005 2005 doi:10.2903/j.efsa.2005.44r
+Pirimiphos-methyl 249-528-5 29232-93-7 single chemical entity Component is identical to the substance Pirimiphos-methyl 249-528-5 29232-93-7 O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate Pirimiphos-methyl C11H20N3O3PS CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1 InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The United Kingdom Pirimiphos-methyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl 31Aug2005 2005 doi:10.2903/j.efsa.2005.44r
+Pirimiphos-methyl 249-528-5 29232-93-7 single chemical entity Component is identical to the substance Pirimiphos-methyl 249-528-5 29232-93-7 O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate Pirimiphos-methyl C11H20N3O3PS CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1 InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: The United Kingdom Pirimiphos-methyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl 31Aug2005 2005 doi:10.2903/j.efsa.2005.44r
+Pirimiphos-methyl 249-528-5 29232-93-7 single chemical entity Component is identical to the substance Pirimiphos-methyl 249-528-5 29232-93-7 O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate Pirimiphos-methyl C11H20N3O3PS CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1 InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The United Kingdom Pirimiphos-methyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl 31Aug2005 2005 doi:10.2903/j.efsa.2005.44r
+Pirimiphos-methyl 249-528-5 29232-93-7 single chemical entity Component is identical to the substance Pirimiphos-methyl 249-528-5 29232-93-7 O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate Pirimiphos-methyl C11H20N3O3PS CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1 InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The United Kingdom Pirimiphos-methyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl 31Aug2005 2005 doi:10.2903/j.efsa.2005.44r
+Pirimiphos-methyl 249-528-5 29232-93-7 single chemical entity Component is identical to the substance Pirimiphos-methyl 249-528-5 29232-93-7 O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate Pirimiphos-methyl C11H20N3O3PS CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1 InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The United Kingdom Pirimiphos-methyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl 31Aug2005 2005 doi:10.2903/j.efsa.2005.44r
+Pirimiphos-methyl 249-528-5 29232-93-7 single chemical entity Component is identical to the substance Pirimiphos-methyl 249-528-5 29232-93-7 O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate Pirimiphos-methyl C11H20N3O3PS CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1 InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The United Kingdom Pirimiphos-methyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl 31Aug2005 2005 doi:10.2903/j.efsa.2005.44r
+Pirimiphos-methyl 249-528-5 29232-93-7 single chemical entity Component is identical to the substance Pirimiphos-methyl 249-528-5 29232-93-7 O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate Pirimiphos-methyl C11H20N3O3PS CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1 InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Positive RMS: The United Kingdom Pirimiphos-methyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl 31Aug2005 2005 doi:10.2903/j.efsa.2005.44r
+Pirimiphos-methyl 249-528-5 29232-93-7 single chemical entity Component is identical to the substance Pirimiphos-methyl 249-528-5 29232-93-7 O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate Pirimiphos-methyl C11H20N3O3PS CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1 InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: The United Kingdom Pirimiphos-methyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl 31Aug2005 2005 doi:10.2903/j.efsa.2005.44r
+Pirimiphos-methyl 249-528-5 29232-93-7 single chemical entity Component is identical to the substance Pirimiphos-methyl 249-528-5 29232-93-7 O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate Pirimiphos-methyl C11H20N3O3PS CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1 InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) Other Not reported no data without Negative RMS: The United Kingdom Pirimiphos-methyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl 31Aug2005 2005 doi:10.2903/j.efsa.2005.44r
+Pirimiphos-methyl 249-528-5 29232-93-7 single chemical entity Component is identical to the substance Pirimiphos-methyl 249-528-5 29232-93-7 O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate Pirimiphos-methyl C11H20N3O3PS CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1 InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) Other Not reported no data without Negative RMS: The United Kingdom Pirimiphos-methyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl 31Aug2005 2005 doi:10.2903/j.efsa.2005.44r
+Pirimiphos-methyl 249-528-5 29232-93-7 single chemical entity Component is identical to the substance Pirimiphos-methyl 249-528-5 29232-93-7 O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate Pirimiphos-methyl C11H20N3O3PS CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1 InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA1532 Not reported no data without Negative RMS: The United Kingdom Pirimiphos-methyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl 31Aug2005 2005 doi:10.2903/j.efsa.2005.44r
+Pirimiphos-methyl 249-528-5 29232-93-7 single chemical entity Component is identical to the substance Pirimiphos-methyl 249-528-5 29232-93-7 O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate Pirimiphos-methyl C11H20N3O3PS CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1 InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) Other Not reported no data with Negative RMS: The United Kingdom Pirimiphos-methyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl 31Aug2005 2005 doi:10.2903/j.efsa.2005.44r
+Pirimiphos-methyl 249-528-5 29232-93-7 single chemical entity Component is identical to the substance Pirimiphos-methyl 249-528-5 29232-93-7 O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate Pirimiphos-methyl C11H20N3O3PS CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1 InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) Other Not reported no data without Positive RMS: The United Kingdom Pirimiphos-methyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl 31Aug2005 2005 doi:10.2903/j.efsa.2005.44r
+Pirimiphos-methyl 249-528-5 29232-93-7 single chemical entity Component is identical to the substance Pirimiphos-methyl 249-528-5 29232-93-7 O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate Pirimiphos-methyl C11H20N3O3PS CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1 InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) G46 Not reported no data without Positive RMS: The United Kingdom Pirimiphos-methyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl 31Aug2005 2005 doi:10.2903/j.efsa.2005.44r
+Pirimiphos-methyl 249-528-5 29232-93-7 single chemical entity Component is identical to the substance Pirimiphos-methyl 249-528-5 29232-93-7 O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate Pirimiphos-methyl C11H20N3O3PS CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1 InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) Other Not reported no data with Positive RMS: The United Kingdom Pirimiphos-methyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl 31Aug2005 2005 doi:10.2903/j.efsa.2005.44r
+Pirimiphos-methyl 249-528-5 29232-93-7 single chemical entity Component is identical to the substance Pirimiphos-methyl 249-528-5 29232-93-7 O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate Pirimiphos-methyl C11H20N3O3PS CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1 InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) G46 Not reported no data with Positive RMS: The United Kingdom Pirimiphos-methyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl 31Aug2005 2005 doi:10.2903/j.efsa.2005.44r
+Pirimiphos-methyl 249-528-5 29232-93-7 single chemical entity Component is identical to the substance Pirimiphos-methyl 249-528-5 29232-93-7 O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate Pirimiphos-methyl C11H20N3O3PS CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1 InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) TA1532 Not reported no data with Negative RMS: The United Kingdom Pirimiphos-methyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl 31Aug2005 2005 doi:10.2903/j.efsa.2005.44r
+Pirimiphos-methyl 249-528-5 29232-93-7 single chemical entity Component is identical to the substance Pirimiphos-methyl 249-528-5 29232-93-7 O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate Pirimiphos-methyl C11H20N3O3PS CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1 InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) Other Not reported no data with Negative RMS: The United Kingdom Pirimiphos-methyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl 31Aug2005 2005 doi:10.2903/j.efsa.2005.44r
+Pirimiphos-methyl 249-528-5 29232-93-7 single chemical entity Component is identical to the substance Pirimiphos-methyl 249-528-5 29232-93-7 O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate Pirimiphos-methyl C11H20N3O3PS CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1 InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable House mouse (as animal) Swiss Male oral: unspecified 6.0000000000 h yes not applicable Negative no evidence RMS: The United Kingdom Pirimiphos-methyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl 31Aug2005 2005 doi:10.2903/j.efsa.2005.44r
+Pirimiphos-methyl 249-528-5 29232-93-7 single chemical entity Component is identical to the substance Pirimiphos-methyl 249-528-5 29232-93-7 O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate Pirimiphos-methyl C11H20N3O3PS CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1 InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable House mouse (as animal) ICR 4 Female Not reported yes not applicable Negative no evidence RMS: The United Kingdom Pirimiphos-methyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl 31Aug2005 2005 doi:10.2903/j.efsa.2005.44r
+Isoxaflutole 604-222-4 141112-29-0 single chemical entity Component is identical to the substance Isoxaflutole 604-222-4 141112-29-0 (5-cyclopropyl-1,2-oxazol-4-yl)-[2-methylsulfonyl-4-(trifluoromethyl)phenyl]methanone Isoxaflutole C15H12F3NO4S CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)C2=C(ON=C2)C3CC3 InChI=1S/C15H12F3NO4S/c1-24(21,22)12-6-9(15(16,17)18)4-5-10(12)13(20)11-7-19-23-14(11)8-2-3-8/h4-8H,2-3H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Italy - CoRMS: Slovenia Isoxaflutole 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance isoxaflutole 24Feb2016 2016 doi:10.2903/j.efsa.2016.4416
+Isoxaflutole 604-222-4 141112-29-0 single chemical entity Component is identical to the substance Isoxaflutole 604-222-4 141112-29-0 (5-cyclopropyl-1,2-oxazol-4-yl)-[2-methylsulfonyl-4-(trifluoromethyl)phenyl]methanone Isoxaflutole C15H12F3NO4S CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)C2=C(ON=C2)C3CC3 InChI=1S/C15H12F3NO4S/c1-24(21,22)12-6-9(15(16,17)18)4-5-10(12)13(20)11-7-19-23-14(11)8-2-3-8/h4-8H,2-3H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: Italy - CoRMS: Slovenia Isoxaflutole 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance isoxaflutole 24Feb2016 2016 doi:10.2903/j.efsa.2016.4416
+Isoxaflutole 604-222-4 141112-29-0 single chemical entity Component is identical to the substance Isoxaflutole 604-222-4 141112-29-0 (5-cyclopropyl-1,2-oxazol-4-yl)-[2-methylsulfonyl-4-(trifluoromethyl)phenyl]methanone Isoxaflutole C15H12F3NO4S CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)C2=C(ON=C2)C3CC3 InChI=1S/C15H12F3NO4S/c1-24(21,22)12-6-9(15(16,17)18)4-5-10(12)13(20)11-7-19-23-14(11)8-2-3-8/h4-8H,2-3H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Italy - CoRMS: Slovenia Isoxaflutole 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance isoxaflutole 24Feb2016 2016 doi:10.2903/j.efsa.2016.4416
+Isoxaflutole 604-222-4 141112-29-0 single chemical entity Component is identical to the substance Isoxaflutole 604-222-4 141112-29-0 (5-cyclopropyl-1,2-oxazol-4-yl)-[2-methylsulfonyl-4-(trifluoromethyl)phenyl]methanone Isoxaflutole C15H12F3NO4S CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)C2=C(ON=C2)C3CC3 InChI=1S/C15H12F3NO4S/c1-24(21,22)12-6-9(15(16,17)18)4-5-10(12)13(20)11-7-19-23-14(11)8-2-3-8/h4-8H,2-3H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Italy - CoRMS: Slovenia Isoxaflutole 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance isoxaflutole 24Feb2016 2016 doi:10.2903/j.efsa.2016.4416
+Isoxaflutole 604-222-4 141112-29-0 single chemical entity Component is identical to the substance Isoxaflutole 604-222-4 141112-29-0 (5-cyclopropyl-1,2-oxazol-4-yl)-[2-methylsulfonyl-4-(trifluoromethyl)phenyl]methanone Isoxaflutole C15H12F3NO4S CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)C2=C(ON=C2)C3CC3 InChI=1S/C15H12F3NO4S/c1-24(21,22)12-6-9(15(16,17)18)4-5-10(12)13(20)11-7-19-23-14(11)8-2-3-8/h4-8H,2-3H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Italy - CoRMS: Slovenia Isoxaflutole 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance isoxaflutole 24Feb2016 2016 doi:10.2903/j.efsa.2016.4416
+Isoxaflutole 604-222-4 141112-29-0 single chemical entity Component is identical to the substance Isoxaflutole 604-222-4 141112-29-0 (5-cyclopropyl-1,2-oxazol-4-yl)-[2-methylsulfonyl-4-(trifluoromethyl)phenyl]methanone Isoxaflutole C15H12F3NO4S CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)C2=C(ON=C2)C3CC3 InChI=1S/C15H12F3NO4S/c1-24(21,22)12-6-9(15(16,17)18)4-5-10(12)13(20)11-7-19-23-14(11)8-2-3-8/h4-8H,2-3H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Italy - CoRMS: Slovenia Isoxaflutole 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance isoxaflutole 24Feb2016 2016 doi:10.2903/j.efsa.2016.4416
+Isoxaflutole 604-222-4 141112-29-0 single chemical entity Component is identical to the substance Isoxaflutole 604-222-4 141112-29-0 (5-cyclopropyl-1,2-oxazol-4-yl)-[2-methylsulfonyl-4-(trifluoromethyl)phenyl]methanone Isoxaflutole C15H12F3NO4S CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)C2=C(ON=C2)C3CC3 InChI=1S/C15H12F3NO4S/c1-24(21,22)12-6-9(15(16,17)18)4-5-10(12)13(20)11-7-19-23-14(11)8-2-3-8/h4-8H,2-3H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Italy - CoRMS: Slovenia Isoxaflutole 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance isoxaflutole 24Feb2016 2016 doi:10.2903/j.efsa.2016.4416
+Isoxaflutole 604-222-4 141112-29-0 single chemical entity Component is identical to the substance Isoxaflutole 604-222-4 141112-29-0 (5-cyclopropyl-1,2-oxazol-4-yl)-[2-methylsulfonyl-4-(trifluoromethyl)phenyl]methanone Isoxaflutole C15H12F3NO4S CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)C2=C(ON=C2)C3CC3 InChI=1S/C15H12F3NO4S/c1-24(21,22)12-6-9(15(16,17)18)4-5-10(12)13(20)11-7-19-23-14(11)8-2-3-8/h4-8H,2-3H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Italy - CoRMS: Slovenia Isoxaflutole 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance isoxaflutole 24Feb2016 2016 doi:10.2903/j.efsa.2016.4416
+Isoxaflutole 604-222-4 141112-29-0 single chemical entity Component is identical to the substance Isoxaflutole 604-222-4 141112-29-0 (5-cyclopropyl-1,2-oxazol-4-yl)-[2-methylsulfonyl-4-(trifluoromethyl)phenyl]methanone Isoxaflutole C15H12F3NO4S CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)C2=C(ON=C2)C3CC3 InChI=1S/C15H12F3NO4S/c1-24(21,22)12-6-9(15(16,17)18)4-5-10(12)13(20)11-7-19-23-14(11)8-2-3-8/h4-8H,2-3H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: Italy - CoRMS: Slovenia Isoxaflutole 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance isoxaflutole 24Feb2016 2016 doi:10.2903/j.efsa.2016.4416
+Isoxaflutole 604-222-4 141112-29-0 single chemical entity Component is identical to the substance Isoxaflutole 604-222-4 141112-29-0 (5-cyclopropyl-1,2-oxazol-4-yl)-[2-methylsulfonyl-4-(trifluoromethyl)phenyl]methanone Isoxaflutole C15H12F3NO4S CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)C2=C(ON=C2)C3CC3 InChI=1S/C15H12F3NO4S/c1-24(21,22)12-6-9(15(16,17)18)4-5-10(12)13(20)11-7-19-23-14(11)8-2-3-8/h4-8H,2-3H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Italy - CoRMS: Slovenia Isoxaflutole 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance isoxaflutole 24Feb2016 2016 doi:10.2903/j.efsa.2016.4416
+Isoxaflutole 604-222-4 141112-29-0 single chemical entity Component is identical to the substance Isoxaflutole 604-222-4 141112-29-0 (5-cyclopropyl-1,2-oxazol-4-yl)-[2-methylsulfonyl-4-(trifluoromethyl)phenyl]methanone Isoxaflutole C15H12F3NO4S CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)C2=C(ON=C2)C3CC3 InChI=1S/C15H12F3NO4S/c1-24(21,22)12-6-9(15(16,17)18)4-5-10(12)13(20)11-7-19-23-14(11)8-2-3-8/h4-8H,2-3H2,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes with Negative RMS: Italy - CoRMS: Slovenia Isoxaflutole 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance isoxaflutole 24Feb2016 2016 doi:10.2903/j.efsa.2016.4416
+Isoxaflutole 604-222-4 141112-29-0 single chemical entity Component is identical to the substance Isoxaflutole 604-222-4 141112-29-0 (5-cyclopropyl-1,2-oxazol-4-yl)-[2-methylsulfonyl-4-(trifluoromethyl)phenyl]methanone Isoxaflutole C15H12F3NO4S CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)C2=C(ON=C2)C3CC3 InChI=1S/C15H12F3NO4S/c1-24(21,22)12-6-9(15(16,17)18)4-5-10(12)13(20)11-7-19-23-14(11)8-2-3-8/h4-8H,2-3H2,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes without Negative RMS: Italy - CoRMS: Slovenia Isoxaflutole 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance isoxaflutole 24Feb2016 2016 doi:10.2903/j.efsa.2016.4416
+Isoxaflutole 604-222-4 141112-29-0 single chemical entity Component is identical to the substance Isoxaflutole 604-222-4 141112-29-0 (5-cyclopropyl-1,2-oxazol-4-yl)-[2-methylsulfonyl-4-(trifluoromethyl)phenyl]methanone Isoxaflutole C15H12F3NO4S CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)C2=C(ON=C2)C3CC3 InChI=1S/C15H12F3NO4S/c1-24(21,22)12-6-9(15(16,17)18)4-5-10(12)13(20)11-7-19-23-14(11)8-2-3-8/h4-8H,2-3H2,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes without Negative RMS: Italy - CoRMS: Slovenia Isoxaflutole 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance isoxaflutole 24Feb2016 2016 doi:10.2903/j.efsa.2016.4416
+Isoxaflutole 604-222-4 141112-29-0 single chemical entity Component is identical to the substance Isoxaflutole 604-222-4 141112-29-0 (5-cyclopropyl-1,2-oxazol-4-yl)-[2-methylsulfonyl-4-(trifluoromethyl)phenyl]methanone Isoxaflutole C15H12F3NO4S CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)C2=C(ON=C2)C3CC3 InChI=1S/C15H12F3NO4S/c1-24(21,22)12-6-9(15(16,17)18)4-5-10(12)13(20)11-7-19-23-14(11)8-2-3-8/h4-8H,2-3H2,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes with Negative RMS: Italy - CoRMS: Slovenia Isoxaflutole 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance isoxaflutole 24Feb2016 2016 doi:10.2903/j.efsa.2016.4416
+Isoxaflutole 604-222-4 141112-29-0 single chemical entity Component is identical to the substance Isoxaflutole 604-222-4 141112-29-0 (5-cyclopropyl-1,2-oxazol-4-yl)-[2-methylsulfonyl-4-(trifluoromethyl)phenyl]methanone Isoxaflutole C15H12F3NO4S CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)C2=C(ON=C2)C3CC3 InChI=1S/C15H12F3NO4S/c1-24(21,22)12-6-9(15(16,17)18)4-5-10(12)13(20)11-7-19-23-14(11)8-2-3-8/h4-8H,2-3H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Negative RMS: Italy - CoRMS: Slovenia Isoxaflutole 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance isoxaflutole 24Feb2016 2016 doi:10.2903/j.efsa.2016.4416
+Isoxaflutole 604-222-4 141112-29-0 single chemical entity Component is identical to the substance Isoxaflutole 604-222-4 141112-29-0 (5-cyclopropyl-1,2-oxazol-4-yl)-[2-methylsulfonyl-4-(trifluoromethyl)phenyl]methanone Isoxaflutole C15H12F3NO4S CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)C2=C(ON=C2)C3CC3 InChI=1S/C15H12F3NO4S/c1-24(21,22)12-6-9(15(16,17)18)4-5-10(12)13(20)11-7-19-23-14(11)8-2-3-8/h4-8H,2-3H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: Italy - CoRMS: Slovenia Isoxaflutole 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance isoxaflutole 24Feb2016 2016 doi:10.2903/j.efsa.2016.4416
+Isoxaflutole 604-222-4 141112-29-0 single chemical entity Component is identical to the substance Isoxaflutole 604-222-4 141112-29-0 (5-cyclopropyl-1,2-oxazol-4-yl)-[2-methylsulfonyl-4-(trifluoromethyl)phenyl]methanone Isoxaflutole C15H12F3NO4S CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)C2=C(ON=C2)C3CC3 InChI=1S/C15H12F3NO4S/c1-24(21,22)12-6-9(15(16,17)18)4-5-10(12)13(20)11-7-19-23-14(11)8-2-3-8/h4-8H,2-3H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Italy - CoRMS: Slovenia Isoxaflutole 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance isoxaflutole 24Feb2016 2016 doi:10.2903/j.efsa.2016.4416
+Isoxaflutole 604-222-4 141112-29-0 single chemical entity Component is identical to the substance Isoxaflutole 604-222-4 141112-29-0 (5-cyclopropyl-1,2-oxazol-4-yl)-[2-methylsulfonyl-4-(trifluoromethyl)phenyl]methanone Isoxaflutole C15H12F3NO4S CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)C2=C(ON=C2)C3CC3 InChI=1S/C15H12F3NO4S/c1-24(21,22)12-6-9(15(16,17)18)4-5-10(12)13(20)11-7-19-23-14(11)8-2-3-8/h4-8H,2-3H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Italy - CoRMS: Slovenia Isoxaflutole 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance isoxaflutole 24Feb2016 2016 doi:10.2903/j.efsa.2016.4416
+Isoxaflutole 604-222-4 141112-29-0 single chemical entity Component is identical to the substance Isoxaflutole 604-222-4 141112-29-0 (5-cyclopropyl-1,2-oxazol-4-yl)-[2-methylsulfonyl-4-(trifluoromethyl)phenyl]methanone Isoxaflutole C15H12F3NO4S CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)C2=C(ON=C2)C3CC3 InChI=1S/C15H12F3NO4S/c1-24(21,22)12-6-9(15(16,17)18)4-5-10(12)13(20)11-7-19-23-14(11)8-2-3-8/h4-8H,2-3H2,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 30 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Italy - CoRMS: Slovenia Isoxaflutole 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance isoxaflutole 24Feb2016 2016 doi:10.2903/j.efsa.2016.4416
+Isoxaflutole 604-222-4 141112-29-0 single chemical entity Component is identical to the substance Isoxaflutole 604-222-4 141112-29-0 (5-cyclopropyl-1,2-oxazol-4-yl)-[2-methylsulfonyl-4-(trifluoromethyl)phenyl]methanone Isoxaflutole C15H12F3NO4S CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)C2=C(ON=C2)C3CC3 InChI=1S/C15H12F3NO4S/c1-24(21,22)12-6-9(15(16,17)18)4-5-10(12)13(20)11-7-19-23-14(11)8-2-3-8/h4-8H,2-3H2,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 30 Male/Female oral: gavage 72.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Italy - CoRMS: Slovenia Isoxaflutole 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance isoxaflutole 24Feb2016 2016 doi:10.2903/j.efsa.2016.4416
+Isoxaflutole 604-222-4 141112-29-0 single chemical entity Component is identical to the substance Isoxaflutole 604-222-4 141112-29-0 (5-cyclopropyl-1,2-oxazol-4-yl)-[2-methylsulfonyl-4-(trifluoromethyl)phenyl]methanone Isoxaflutole C15H12F3NO4S CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)C2=C(ON=C2)C3CC3 InChI=1S/C15H12F3NO4S/c1-24(21,22)12-6-9(15(16,17)18)4-5-10(12)13(20)11-7-19-23-14(11)8-2-3-8/h4-8H,2-3H2,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 30 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Italy - CoRMS: Slovenia Isoxaflutole 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance isoxaflutole 24Feb2016 2016 doi:10.2903/j.efsa.2016.4416
+Isoxaflutole 604-222-4 141112-29-0 single chemical entity Component is identical to the substance Isoxaflutole 604-222-4 141112-29-0 (5-cyclopropyl-1,2-oxazol-4-yl)-[2-methylsulfonyl-4-(trifluoromethyl)phenyl]methanone Isoxaflutole C15H12F3NO4S CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)C2=C(ON=C2)C3CC3 InChI=1S/C15H12F3NO4S/c1-24(21,22)12-6-9(15(16,17)18)4-5-10(12)13(20)11-7-19-23-14(11)8-2-3-8/h4-8H,2-3H2,1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Sprague-Dawley 4 Male oral: unspecified 14.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Italy - CoRMS: Slovenia Isoxaflutole 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance isoxaflutole 24Feb2016 2016 doi:10.2903/j.efsa.2016.4416
+Isoxaflutole 604-222-4 141112-29-0 single chemical entity Component is identical to the substance Isoxaflutole 604-222-4 141112-29-0 (5-cyclopropyl-1,2-oxazol-4-yl)-[2-methylsulfonyl-4-(trifluoromethyl)phenyl]methanone Isoxaflutole C15H12F3NO4S CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)C2=C(ON=C2)C3CC3 InChI=1S/C15H12F3NO4S/c1-24(21,22)12-6-9(15(16,17)18)4-5-10(12)13(20)11-7-19-23-14(11)8-2-3-8/h4-8H,2-3H2,1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Sprague-Dawley 4 Male oral: unspecified 2.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Italy - CoRMS: Slovenia Isoxaflutole 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance isoxaflutole 24Feb2016 2016 doi:10.2903/j.efsa.2016.4416
+Isoxaflutole 604-222-4 141112-29-0 single chemical entity Component is a metabolite of the substance (2RS)-3-cyclopropyl-2-[2-(methylsulfonyl)-4-(trifluoromethyl)benzoyl]-3-oxopropanenitrile 3-cyclopropyl-2-[2-(methylsulfonyl)-4-(trifluoromethyl)benzoyl]-3-oxopropanenitrile Not in list C15H12F3NO4S O=C(C(C#N)C(=O)C1CC1)c2ccc(cc2S(C)(=O)=O)C(F)(F)F InChI=1S/C15H12F3NO4S/c1-24(22,23)12-6-9(15(16,17)18)4-5-10(12)14(21)11(7-19)13(20)8-2-3-8/h4-6,8,11H,2-3H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Italy - CoRMS: Slovenia Isoxaflutole 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance isoxaflutole 24Feb2016 2016 doi:10.2903/j.efsa.2016.4416
+Isoxaflutole 604-222-4 141112-29-0 single chemical entity Component is a metabolite of the substance (2RS)-3-cyclopropyl-2-[2-(methylsulfonyl)-4-(trifluoromethyl)benzoyl]-3-oxopropanenitrile 3-cyclopropyl-2-[2-(methylsulfonyl)-4-(trifluoromethyl)benzoyl]-3-oxopropanenitrile Not in list C15H12F3NO4S O=C(C(C#N)C(=O)C1CC1)c2ccc(cc2S(C)(=O)=O)C(F)(F)F InChI=1S/C15H12F3NO4S/c1-24(22,23)12-6-9(15(16,17)18)4-5-10(12)14(21)11(7-19)13(20)8-2-3-8/h4-6,8,11H,2-3H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Italy - CoRMS: Slovenia Isoxaflutole 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance isoxaflutole 24Feb2016 2016 doi:10.2903/j.efsa.2016.4416
+Isoxaflutole 604-222-4 141112-29-0 single chemical entity Component is a metabolite of the substance (2RS)-3-cyclopropyl-2-[2-(methylsulfonyl)-4-(trifluoromethyl)benzoyl]-3-oxopropanenitrile 3-cyclopropyl-2-[2-(methylsulfonyl)-4-(trifluoromethyl)benzoyl]-3-oxopropanenitrile Not in list C15H12F3NO4S O=C(C(C#N)C(=O)C1CC1)c2ccc(cc2S(C)(=O)=O)C(F)(F)F InChI=1S/C15H12F3NO4S/c1-24(22,23)12-6-9(15(16,17)18)4-5-10(12)14(21)11(7-19)13(20)8-2-3-8/h4-6,8,11H,2-3H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Italy - CoRMS: Slovenia Isoxaflutole 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance isoxaflutole 24Feb2016 2016 doi:10.2903/j.efsa.2016.4416
+Isoxaflutole 604-222-4 141112-29-0 single chemical entity Component is a metabolite of the substance (2RS)-3-cyclopropyl-2-[2-(methylsulfonyl)-4-(trifluoromethyl)benzoyl]-3-oxopropanenitrile 3-cyclopropyl-2-[2-(methylsulfonyl)-4-(trifluoromethyl)benzoyl]-3-oxopropanenitrile Not in list C15H12F3NO4S O=C(C(C#N)C(=O)C1CC1)c2ccc(cc2S(C)(=O)=O)C(F)(F)F InChI=1S/C15H12F3NO4S/c1-24(22,23)12-6-9(15(16,17)18)4-5-10(12)14(21)11(7-19)13(20)8-2-3-8/h4-6,8,11H,2-3H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Italy - CoRMS: Slovenia Isoxaflutole 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance isoxaflutole 24Feb2016 2016 doi:10.2903/j.efsa.2016.4416
+Isoxaflutole 604-222-4 141112-29-0 single chemical entity Component is a metabolite of the substance (2RS)-3-cyclopropyl-2-[2-(methylsulfonyl)-4-(trifluoromethyl)benzoyl]-3-oxopropanenitrile 3-cyclopropyl-2-[2-(methylsulfonyl)-4-(trifluoromethyl)benzoyl]-3-oxopropanenitrile Not in list C15H12F3NO4S O=C(C(C#N)C(=O)C1CC1)c2ccc(cc2S(C)(=O)=O)C(F)(F)F InChI=1S/C15H12F3NO4S/c1-24(22,23)12-6-9(15(16,17)18)4-5-10(12)14(21)11(7-19)13(20)8-2-3-8/h4-6,8,11H,2-3H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes without Negative RMS: Italy - CoRMS: Slovenia Isoxaflutole 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance isoxaflutole 24Feb2016 2016 doi:10.2903/j.efsa.2016.4416
+Isoxaflutole 604-222-4 141112-29-0 single chemical entity Component is a metabolite of the substance (2RS)-3-cyclopropyl-2-[2-(methylsulfonyl)-4-(trifluoromethyl)benzoyl]-3-oxopropanenitrile 3-cyclopropyl-2-[2-(methylsulfonyl)-4-(trifluoromethyl)benzoyl]-3-oxopropanenitrile Not in list C15H12F3NO4S O=C(C(C#N)C(=O)C1CC1)c2ccc(cc2S(C)(=O)=O)C(F)(F)F InChI=1S/C15H12F3NO4S/c1-24(22,23)12-6-9(15(16,17)18)4-5-10(12)14(21)11(7-19)13(20)8-2-3-8/h4-6,8,11H,2-3H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes with Negative RMS: Italy - CoRMS: Slovenia Isoxaflutole 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance isoxaflutole 24Feb2016 2016 doi:10.2903/j.efsa.2016.4416
+Isoxaflutole 604-222-4 141112-29-0 single chemical entity Component is a metabolite of the substance (2RS)-3-cyclopropyl-2-[2-(methylsulfonyl)-4-(trifluoromethyl)benzoyl]-3-oxopropanenitrile 3-cyclopropyl-2-[2-(methylsulfonyl)-4-(trifluoromethyl)benzoyl]-3-oxopropanenitrile Not in list C15H12F3NO4S O=C(C(C#N)C(=O)C1CC1)c2ccc(cc2S(C)(=O)=O)C(F)(F)F InChI=1S/C15H12F3NO4S/c1-24(22,23)12-6-9(15(16,17)18)4-5-10(12)14(21)11(7-19)13(20)8-2-3-8/h4-6,8,11H,2-3H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Italy - CoRMS: Slovenia Isoxaflutole 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance isoxaflutole 24Feb2016 2016 doi:10.2903/j.efsa.2016.4416
+Isoxaflutole 604-222-4 141112-29-0 single chemical entity Component is a metabolite of the substance (2RS)-3-cyclopropyl-2-[2-(methylsulfonyl)-4-(trifluoromethyl)benzoyl]-3-oxopropanenitrile 3-cyclopropyl-2-[2-(methylsulfonyl)-4-(trifluoromethyl)benzoyl]-3-oxopropanenitrile Not in list C15H12F3NO4S O=C(C(C#N)C(=O)C1CC1)c2ccc(cc2S(C)(=O)=O)C(F)(F)F InChI=1S/C15H12F3NO4S/c1-24(22,23)12-6-9(15(16,17)18)4-5-10(12)14(21)11(7-19)13(20)8-2-3-8/h4-6,8,11H,2-3H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Italy - CoRMS: Slovenia Isoxaflutole 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance isoxaflutole 24Feb2016 2016 doi:10.2903/j.efsa.2016.4416
+Isoxaflutole 604-222-4 141112-29-0 single chemical entity Component is a metabolite of the substance (2RS)-3-cyclopropyl-2-[2-(methylsulfonyl)-4-(trifluoromethyl)benzoyl]-3-oxopropanenitrile 3-cyclopropyl-2-[2-(methylsulfonyl)-4-(trifluoromethyl)benzoyl]-3-oxopropanenitrile Not in list C15H12F3NO4S O=C(C(C#N)C(=O)C1CC1)c2ccc(cc2S(C)(=O)=O)C(F)(F)F InChI=1S/C15H12F3NO4S/c1-24(22,23)12-6-9(15(16,17)18)4-5-10(12)14(21)11(7-19)13(20)8-2-3-8/h4-6,8,11H,2-3H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Italy - CoRMS: Slovenia Isoxaflutole 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance isoxaflutole 24Feb2016 2016 doi:10.2903/j.efsa.2016.4416
+Isoxaflutole 604-222-4 141112-29-0 single chemical entity Component is a metabolite of the substance (2RS)-3-cyclopropyl-2-[2-(methylsulfonyl)-4-(trifluoromethyl)benzoyl]-3-oxopropanenitrile 3-cyclopropyl-2-[2-(methylsulfonyl)-4-(trifluoromethyl)benzoyl]-3-oxopropanenitrile Not in list C15H12F3NO4S O=C(C(C#N)C(=O)C1CC1)c2ccc(cc2S(C)(=O)=O)C(F)(F)F InChI=1S/C15H12F3NO4S/c1-24(22,23)12-6-9(15(16,17)18)4-5-10(12)14(21)11(7-19)13(20)8-2-3-8/h4-6,8,11H,2-3H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Italy - CoRMS: Slovenia Isoxaflutole 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance isoxaflutole 24Feb2016 2016 doi:10.2903/j.efsa.2016.4416
+Isoxaflutole 604-222-4 141112-29-0 single chemical entity Component is a metabolite of the substance 2-mesyl-4-trifluoromethylbenzoic acid 142994-06-7 2-methylsulfonyl-4-(trifluoromethyl)benzoic acid Not in list C9H7F3O4S CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)O InChI=1S/C9H7F3O4S/c1-17(15,16)7-4-5(9(10,11)12)2-3-6(7)8(13)14/h2-4H,1H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Italy - CoRMS: Slovenia Isoxaflutole 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance isoxaflutole 24Feb2016 2016 doi:10.2903/j.efsa.2016.4416
+Isoxaflutole 604-222-4 141112-29-0 single chemical entity Component is a metabolite of the substance 2-mesyl-4-trifluoromethylbenzoic acid 142994-06-7 2-methylsulfonyl-4-(trifluoromethyl)benzoic acid Not in list C9H7F3O4S CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)O InChI=1S/C9H7F3O4S/c1-17(15,16)7-4-5(9(10,11)12)2-3-6(7)8(13)14/h2-4H,1H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Italy - CoRMS: Slovenia Isoxaflutole 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance isoxaflutole 24Feb2016 2016 doi:10.2903/j.efsa.2016.4416
+Isoxaflutole 604-222-4 141112-29-0 single chemical entity Component is a metabolite of the substance 2-mesyl-4-trifluoromethylbenzoic acid 142994-06-7 2-methylsulfonyl-4-(trifluoromethyl)benzoic acid Not in list C9H7F3O4S CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)O InChI=1S/C9H7F3O4S/c1-17(15,16)7-4-5(9(10,11)12)2-3-6(7)8(13)14/h2-4H,1H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Italy - CoRMS: Slovenia Isoxaflutole 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance isoxaflutole 24Feb2016 2016 doi:10.2903/j.efsa.2016.4416
+Isoxaflutole 604-222-4 141112-29-0 single chemical entity Component is a metabolite of the substance 2-mesyl-4-trifluoromethylbenzoic acid 142994-06-7 2-methylsulfonyl-4-(trifluoromethyl)benzoic acid Not in list C9H7F3O4S CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)O InChI=1S/C9H7F3O4S/c1-17(15,16)7-4-5(9(10,11)12)2-3-6(7)8(13)14/h2-4H,1H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Italy - CoRMS: Slovenia Isoxaflutole 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance isoxaflutole 24Feb2016 2016 doi:10.2903/j.efsa.2016.4416
+Isoxaflutole 604-222-4 141112-29-0 single chemical entity Component is a metabolite of the substance 2-mesyl-4-trifluoromethylbenzoic acid 142994-06-7 2-methylsulfonyl-4-(trifluoromethyl)benzoic acid Not in list C9H7F3O4S CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)O InChI=1S/C9H7F3O4S/c1-17(15,16)7-4-5(9(10,11)12)2-3-6(7)8(13)14/h2-4H,1H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Italy - CoRMS: Slovenia Isoxaflutole 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance isoxaflutole 24Feb2016 2016 doi:10.2903/j.efsa.2016.4416
+Isoxaflutole 604-222-4 141112-29-0 single chemical entity Component is a metabolite of the substance 2-mesyl-4-trifluoromethylbenzoic acid 142994-06-7 2-methylsulfonyl-4-(trifluoromethyl)benzoic acid Not in list C9H7F3O4S CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)O InChI=1S/C9H7F3O4S/c1-17(15,16)7-4-5(9(10,11)12)2-3-6(7)8(13)14/h2-4H,1H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Italy - CoRMS: Slovenia Isoxaflutole 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance isoxaflutole 24Feb2016 2016 doi:10.2903/j.efsa.2016.4416
+Isoxaflutole 604-222-4 141112-29-0 single chemical entity Component is a metabolite of the substance 2-mesyl-4-trifluoromethylbenzoic acid 142994-06-7 2-methylsulfonyl-4-(trifluoromethyl)benzoic acid Not in list C9H7F3O4S CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)O InChI=1S/C9H7F3O4S/c1-17(15,16)7-4-5(9(10,11)12)2-3-6(7)8(13)14/h2-4H,1H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Italy - CoRMS: Slovenia Isoxaflutole 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance isoxaflutole 24Feb2016 2016 doi:10.2903/j.efsa.2016.4416
+Isoxaflutole 604-222-4 141112-29-0 single chemical entity Component is a metabolite of the substance 2-mesyl-4-trifluoromethylbenzoic acid 142994-06-7 2-methylsulfonyl-4-(trifluoromethyl)benzoic acid Not in list C9H7F3O4S CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)O InChI=1S/C9H7F3O4S/c1-17(15,16)7-4-5(9(10,11)12)2-3-6(7)8(13)14/h2-4H,1H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Italy - CoRMS: Slovenia Isoxaflutole 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance isoxaflutole 24Feb2016 2016 doi:10.2903/j.efsa.2016.4416
+Isoxaflutole 604-222-4 141112-29-0 single chemical entity Component is a metabolite of the substance 2-mesyl-4-trifluoromethylbenzoic acid 142994-06-7 2-methylsulfonyl-4-(trifluoromethyl)benzoic acid Not in list C9H7F3O4S CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)O InChI=1S/C9H7F3O4S/c1-17(15,16)7-4-5(9(10,11)12)2-3-6(7)8(13)14/h2-4H,1H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No data Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Italy - CoRMS: Slovenia Isoxaflutole 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance isoxaflutole 24Feb2016 2016 doi:10.2903/j.efsa.2016.4416
+Isoxaflutole 604-222-4 141112-29-0 single chemical entity Component is a metabolite of the substance 2-mesyl-4-trifluoromethylbenzoic acid 142994-06-7 2-methylsulfonyl-4-(trifluoromethyl)benzoic acid Not in list C9H7F3O4S CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)O InChI=1S/C9H7F3O4S/c1-17(15,16)7-4-5(9(10,11)12)2-3-6(7)8(13)14/h2-4H,1H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No data Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Italy - CoRMS: Slovenia Isoxaflutole 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance isoxaflutole 24Feb2016 2016 doi:10.2903/j.efsa.2016.4416
+Isoxaflutole 604-222-4 141112-29-0 single chemical entity Component is a metabolite of the substance 2-mesyl-4-trifluoromethylbenzoic acid 142994-06-7 2-methylsulfonyl-4-(trifluoromethyl)benzoic acid Not in list C9H7F3O4S CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)O InChI=1S/C9H7F3O4S/c1-17(15,16)7-4-5(9(10,11)12)2-3-6(7)8(13)14/h2-4H,1H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No data Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Italy - CoRMS: Slovenia Isoxaflutole 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance isoxaflutole 24Feb2016 2016 doi:10.2903/j.efsa.2016.4416
+Isoxaflutole 604-222-4 141112-29-0 single chemical entity Component is a metabolite of the substance 2-mesyl-4-trifluoromethylbenzoic acid 142994-06-7 2-methylsulfonyl-4-(trifluoromethyl)benzoic acid Not in list C9H7F3O4S CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)O InChI=1S/C9H7F3O4S/c1-17(15,16)7-4-5(9(10,11)12)2-3-6(7)8(13)14/h2-4H,1H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No data Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Italy - CoRMS: Slovenia Isoxaflutole 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance isoxaflutole 24Feb2016 2016 doi:10.2903/j.efsa.2016.4416
+Isoxaflutole 604-222-4 141112-29-0 single chemical entity Component is a metabolite of the substance 2-mesyl-4-trifluoromethylbenzoic acid 142994-06-7 2-methylsulfonyl-4-(trifluoromethyl)benzoic acid Not in list C9H7F3O4S CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)O InChI=1S/C9H7F3O4S/c1-17(15,16)7-4-5(9(10,11)12)2-3-6(7)8(13)14/h2-4H,1H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable House mouse (as animal) CD-1 6 Male oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Italy - CoRMS: Slovenia Isoxaflutole 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance isoxaflutole 24Feb2016 2016 doi:10.2903/j.efsa.2016.4416
+Isoxaflutole 604-222-4 141112-29-0 single chemical entity Component is a metabolite of the substance 2-mesyl-4-trifluoromethylbenzoic acid 142994-06-7 2-methylsulfonyl-4-(trifluoromethyl)benzoic acid Not in list C9H7F3O4S CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)O InChI=1S/C9H7F3O4S/c1-17(15,16)7-4-5(9(10,11)12)2-3-6(7)8(13)14/h2-4H,1H3,(H,13,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable House mouse (as animal) CD-1 6 Male oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Italy - CoRMS: Slovenia Isoxaflutole 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance isoxaflutole 24Feb2016 2016 doi:10.2903/j.efsa.2016.4416
+Pinoxaden 243973-20-8 single chemical entity Component is identical to the substance Pinoxaden 243973-20-8 [8-(2,6-diethyl-4-methylphenyl)-7-oxo-1,2,4,5-tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepin-9-yl] 2,2-dimethylpropanoate Pinoxaden C23H32N2O4 CCC1=CC(=CC(=C1C2=C(N3CCOCCN3C2=O)OC(=O)C(C)(C)C)CC)C InChI=1S/C23H32N2O4/c1-7-16-13-15(3)14-17(8-2)18(16)19-20(26)24-9-11-28-12-10-25(24)21(19)29-22(27)23(4,5)6/h13-14H,7-12H2,1-6H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is identical to the substance Pinoxaden 243973-20-8 [8-(2,6-diethyl-4-methylphenyl)-7-oxo-1,2,4,5-tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepin-9-yl] 2,2-dimethylpropanoate Pinoxaden C23H32N2O4 CCC1=CC(=CC(=C1C2=C(N3CCOCCN3C2=O)OC(=O)C(C)(C)C)CC)C InChI=1S/C23H32N2O4/c1-7-16-13-15(3)14-17(8-2)18(16)19-20(26)24-9-11-28-12-10-25(24)21(19)29-22(27)23(4,5)6/h13-14H,7-12H2,1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is identical to the substance Pinoxaden 243973-20-8 [8-(2,6-diethyl-4-methylphenyl)-7-oxo-1,2,4,5-tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepin-9-yl] 2,2-dimethylpropanoate Pinoxaden C23H32N2O4 CCC1=CC(=CC(=C1C2=C(N3CCOCCN3C2=O)OC(=O)C(C)(C)C)CC)C InChI=1S/C23H32N2O4/c1-7-16-13-15(3)14-17(8-2)18(16)19-20(26)24-9-11-28-12-10-25(24)21(19)29-22(27)23(4,5)6/h13-14H,7-12H2,1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is identical to the substance Pinoxaden 243973-20-8 [8-(2,6-diethyl-4-methylphenyl)-7-oxo-1,2,4,5-tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepin-9-yl] 2,2-dimethylpropanoate Pinoxaden C23H32N2O4 CCC1=CC(=CC(=C1C2=C(N3CCOCCN3C2=O)OC(=O)C(C)(C)C)CC)C InChI=1S/C23H32N2O4/c1-7-16-13-15(3)14-17(8-2)18(16)19-20(26)24-9-11-28-12-10-25(24)21(19)29-22(27)23(4,5)6/h13-14H,7-12H2,1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is identical to the substance Pinoxaden 243973-20-8 [8-(2,6-diethyl-4-methylphenyl)-7-oxo-1,2,4,5-tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepin-9-yl] 2,2-dimethylpropanoate Pinoxaden C23H32N2O4 CCC1=CC(=CC(=C1C2=C(N3CCOCCN3C2=O)OC(=O)C(C)(C)C)CC)C InChI=1S/C23H32N2O4/c1-7-16-13-15(3)14-17(8-2)18(16)19-20(26)24-9-11-28-12-10-25(24)21(19)29-22(27)23(4,5)6/h13-14H,7-12H2,1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is identical to the substance Pinoxaden 243973-20-8 [8-(2,6-diethyl-4-methylphenyl)-7-oxo-1,2,4,5-tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepin-9-yl] 2,2-dimethylpropanoate Pinoxaden C23H32N2O4 CCC1=CC(=CC(=C1C2=C(N3CCOCCN3C2=O)OC(=O)C(C)(C)C)CC)C InChI=1S/C23H32N2O4/c1-7-16-13-15(3)14-17(8-2)18(16)19-20(26)24-9-11-28-12-10-25(24)21(19)29-22(27)23(4,5)6/h13-14H,7-12H2,1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is identical to the substance Pinoxaden 243973-20-8 [8-(2,6-diethyl-4-methylphenyl)-7-oxo-1,2,4,5-tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepin-9-yl] 2,2-dimethylpropanoate Pinoxaden C23H32N2O4 CCC1=CC(=CC(=C1C2=C(N3CCOCCN3C2=O)OC(=O)C(C)(C)C)CC)C InChI=1S/C23H32N2O4/c1-7-16-13-15(3)14-17(8-2)18(16)19-20(26)24-9-11-28-12-10-25(24)21(19)29-22(27)23(4,5)6/h13-14H,7-12H2,1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is identical to the substance Pinoxaden 243973-20-8 [8-(2,6-diethyl-4-methylphenyl)-7-oxo-1,2,4,5-tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepin-9-yl] 2,2-dimethylpropanoate Pinoxaden C23H32N2O4 CCC1=CC(=CC(=C1C2=C(N3CCOCCN3C2=O)OC(=O)C(C)(C)C)CC)C InChI=1S/C23H32N2O4/c1-7-16-13-15(3)14-17(8-2)18(16)19-20(26)24-9-11-28-12-10-25(24)21(19)29-22(27)23(4,5)6/h13-14H,7-12H2,1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is identical to the substance Pinoxaden 243973-20-8 [8-(2,6-diethyl-4-methylphenyl)-7-oxo-1,2,4,5-tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepin-9-yl] 2,2-dimethylpropanoate Pinoxaden C23H32N2O4 CCC1=CC(=CC(=C1C2=C(N3CCOCCN3C2=O)OC(=O)C(C)(C)C)CC)C InChI=1S/C23H32N2O4/c1-7-16-13-15(3)14-17(8-2)18(16)19-20(26)24-9-11-28-12-10-25(24)21(19)29-22(27)23(4,5)6/h13-14H,7-12H2,1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is identical to the substance Pinoxaden 243973-20-8 [8-(2,6-diethyl-4-methylphenyl)-7-oxo-1,2,4,5-tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepin-9-yl] 2,2-dimethylpropanoate Pinoxaden C23H32N2O4 CCC1=CC(=CC(=C1C2=C(N3CCOCCN3C2=O)OC(=O)C(C)(C)C)CC)C InChI=1S/C23H32N2O4/c1-7-16-13-15(3)14-17(8-2)18(16)19-20(26)24-9-11-28-12-10-25(24)21(19)29-22(27)23(4,5)6/h13-14H,7-12H2,1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is identical to the substance Pinoxaden 243973-20-8 [8-(2,6-diethyl-4-methylphenyl)-7-oxo-1,2,4,5-tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepin-9-yl] 2,2-dimethylpropanoate Pinoxaden C23H32N2O4 CCC1=CC(=CC(=C1C2=C(N3CCOCCN3C2=O)OC(=O)C(C)(C)C)CC)C InChI=1S/C23H32N2O4/c1-7-16-13-15(3)14-17(8-2)18(16)19-20(26)24-9-11-28-12-10-25(24)21(19)29-22(27)23(4,5)6/h13-14H,7-12H2,1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is identical to the substance Pinoxaden 243973-20-8 [8-(2,6-diethyl-4-methylphenyl)-7-oxo-1,2,4,5-tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepin-9-yl] 2,2-dimethylpropanoate Pinoxaden C23H32N2O4 CCC1=CC(=CC(=C1C2=C(N3CCOCCN3C2=O)OC(=O)C(C)(C)C)CC)C InChI=1S/C23H32N2O4/c1-7-16-13-15(3)14-17(8-2)18(16)19-20(26)24-9-11-28-12-10-25(24)21(19)29-22(27)23(4,5)6/h13-14H,7-12H2,1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is identical to the substance Pinoxaden 243973-20-8 [8-(2,6-diethyl-4-methylphenyl)-7-oxo-1,2,4,5-tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepin-9-yl] 2,2-dimethylpropanoate Pinoxaden C23H32N2O4 CCC1=CC(=CC(=C1C2=C(N3CCOCCN3C2=O)OC(=O)C(C)(C)C)CC)C InChI=1S/C23H32N2O4/c1-7-16-13-15(3)14-17(8-2)18(16)19-20(26)24-9-11-28-12-10-25(24)21(19)29-22(27)23(4,5)6/h13-14H,7-12H2,1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is identical to the substance Pinoxaden 243973-20-8 [8-(2,6-diethyl-4-methylphenyl)-7-oxo-1,2,4,5-tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepin-9-yl] 2,2-dimethylpropanoate Pinoxaden C23H32N2O4 CCC1=CC(=CC(=C1C2=C(N3CCOCCN3C2=O)OC(=O)C(C)(C)C)CC)C InChI=1S/C23H32N2O4/c1-7-16-13-15(3)14-17(8-2)18(16)19-20(26)24-9-11-28-12-10-25(24)21(19)29-22(27)23(4,5)6/h13-14H,7-12H2,1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative small colonies RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is identical to the substance Pinoxaden 243973-20-8 [8-(2,6-diethyl-4-methylphenyl)-7-oxo-1,2,4,5-tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepin-9-yl] 2,2-dimethylpropanoate Pinoxaden C23H32N2O4 CCC1=CC(=CC(=C1C2=C(N3CCOCCN3C2=O)OC(=O)C(C)(C)C)CC)C InChI=1S/C23H32N2O4/c1-7-16-13-15(3)14-17(8-2)18(16)19-20(26)24-9-11-28-12-10-25(24)21(19)29-22(27)23(4,5)6/h13-14H,7-12H2,1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Negative small colonies RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is identical to the substance Pinoxaden 243973-20-8 [8-(2,6-diethyl-4-methylphenyl)-7-oxo-1,2,4,5-tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepin-9-yl] 2,2-dimethylpropanoate Pinoxaden C23H32N2O4 CCC1=CC(=CC(=C1C2=C(N3CCOCCN3C2=O)OC(=O)C(C)(C)C)CC)C InChI=1S/C23H32N2O4/c1-7-16-13-15(3)14-17(8-2)18(16)19-20(26)24-9-11-28-12-10-25(24)21(19)29-22(27)23(4,5)6/h13-14H,7-12H2,1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative large colonies RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is identical to the substance Pinoxaden 243973-20-8 [8-(2,6-diethyl-4-methylphenyl)-7-oxo-1,2,4,5-tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepin-9-yl] 2,2-dimethylpropanoate Pinoxaden C23H32N2O4 CCC1=CC(=CC(=C1C2=C(N3CCOCCN3C2=O)OC(=O)C(C)(C)C)CC)C InChI=1S/C23H32N2O4/c1-7-16-13-15(3)14-17(8-2)18(16)19-20(26)24-9-11-28-12-10-25(24)21(19)29-22(27)23(4,5)6/h13-14H,7-12H2,1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Negative large colonies RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is identical to the substance Pinoxaden 243973-20-8 [8-(2,6-diethyl-4-methylphenyl)-7-oxo-1,2,4,5-tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepin-9-yl] 2,2-dimethylpropanoate Pinoxaden C23H32N2O4 CCC1=CC(=CC(=C1C2=C(N3CCOCCN3C2=O)OC(=O)C(C)(C)C)CC)C InChI=1S/C23H32N2O4/c1-7-16-13-15(3)14-17(8-2)18(16)19-20(26)24-9-11-28-12-10-25(24)21(19)29-22(27)23(4,5)6/h13-14H,7-12H2,1-6H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Positive RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is identical to the substance Pinoxaden 243973-20-8 [8-(2,6-diethyl-4-methylphenyl)-7-oxo-1,2,4,5-tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepin-9-yl] 2,2-dimethylpropanoate Pinoxaden C23H32N2O4 CCC1=CC(=CC(=C1C2=C(N3CCOCCN3C2=O)OC(=O)C(C)(C)C)CC)C InChI=1S/C23H32N2O4/c1-7-16-13-15(3)14-17(8-2)18(16)19-20(26)24-9-11-28-12-10-25(24)21(19)29-22(27)23(4,5)6/h13-14H,7-12H2,1-6H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Positive RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is identical to the substance Pinoxaden 243973-20-8 [8-(2,6-diethyl-4-methylphenyl)-7-oxo-1,2,4,5-tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepin-9-yl] 2,2-dimethylpropanoate Pinoxaden C23H32N2O4 CCC1=CC(=CC(=C1C2=C(N3CCOCCN3C2=O)OC(=O)C(C)(C)C)CC)C InChI=1S/C23H32N2O4/c1-7-16-13-15(3)14-17(8-2)18(16)19-20(26)24-9-11-28-12-10-25(24)21(19)29-22(27)23(4,5)6/h13-14H,7-12H2,1-6H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Positive RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is identical to the substance Pinoxaden 243973-20-8 [8-(2,6-diethyl-4-methylphenyl)-7-oxo-1,2,4,5-tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepin-9-yl] 2,2-dimethylpropanoate Pinoxaden C23H32N2O4 CCC1=CC(=CC(=C1C2=C(N3CCOCCN3C2=O)OC(=O)C(C)(C)C)CC)C InChI=1S/C23H32N2O4/c1-7-16-13-15(3)14-17(8-2)18(16)19-20(26)24-9-11-28-12-10-25(24)21(19)29-22(27)23(4,5)6/h13-14H,7-12H2,1-6H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Positive RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is identical to the substance Pinoxaden 243973-20-8 [8-(2,6-diethyl-4-methylphenyl)-7-oxo-1,2,4,5-tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepin-9-yl] 2,2-dimethylpropanoate Pinoxaden C23H32N2O4 CCC1=CC(=CC(=C1C2=C(N3CCOCCN3C2=O)OC(=O)C(C)(C)C)CC)C InChI=1S/C23H32N2O4/c1-7-16-13-15(3)14-17(8-2)18(16)19-20(26)24-9-11-28-12-10-25(24)21(19)29-22(27)23(4,5)6/h13-14H,7-12H2,1-6H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is identical to the substance Pinoxaden 243973-20-8 [8-(2,6-diethyl-4-methylphenyl)-7-oxo-1,2,4,5-tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepin-9-yl] 2,2-dimethylpropanoate Pinoxaden C23H32N2O4 CCC1=CC(=CC(=C1C2=C(N3CCOCCN3C2=O)OC(=O)C(C)(C)C)CC)C InChI=1S/C23H32N2O4/c1-7-16-13-15(3)14-17(8-2)18(16)19-20(26)24-9-11-28-12-10-25(24)21(19)29-22(27)23(4,5)6/h13-14H,7-12H2,1-6H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female oral: unspecified 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is identical to the substance Pinoxaden 243973-20-8 [8-(2,6-diethyl-4-methylphenyl)-7-oxo-1,2,4,5-tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepin-9-yl] 2,2-dimethylpropanoate Pinoxaden C23H32N2O4 CCC1=CC(=CC(=C1C2=C(N3CCOCCN3C2=O)OC(=O)C(C)(C)C)CC)C InChI=1S/C23H32N2O4/c1-7-16-13-15(3)14-17(8-2)18(16)19-20(26)24-9-11-28-12-10-25(24)21(19)29-22(27)23(4,5)6/h13-14H,7-12H2,1-6H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Alpk:APf SD Rat 3 Male Not reported 2.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is identical to the substance Pinoxaden 243973-20-8 [8-(2,6-diethyl-4-methylphenyl)-7-oxo-1,2,4,5-tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepin-9-yl] 2,2-dimethylpropanoate Pinoxaden C23H32N2O4 CCC1=CC(=CC(=C1C2=C(N3CCOCCN3C2=O)OC(=O)C(C)(C)C)CC)C InChI=1S/C23H32N2O4/c1-7-16-13-15(3)14-17(8-2)18(16)19-20(26)24-9-11-28-12-10-25(24)21(19)29-22(27)23(4,5)6/h13-14H,7-12H2,1-6H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Alpk:APf SD Rat 3 Male Not reported 16.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is a metabolite of the substance Pinoxaden metabolite (NOA 447204) 8-(2,6-diethyl-4-methyl-phenyl)-8-hydroxy -tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepine-7,9-dione Not in list C18H24N2O4 CCc1cc(C)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O InChI=1S/C18H24N2O4/c1-4-13-10-12(3)11-14(5-2)15(13)18(23)16(21)19-6-8-24-9-7-20(19)17(18)22/h10-11,23H,4-9H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is a metabolite of the substance Pinoxaden metabolite (NOA 447204) 8-(2,6-diethyl-4-methyl-phenyl)-8-hydroxy -tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepine-7,9-dione Not in list C18H24N2O4 CCc1cc(C)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O InChI=1S/C18H24N2O4/c1-4-13-10-12(3)11-14(5-2)15(13)18(23)16(21)19-6-8-24-9-7-20(19)17(18)22/h10-11,23H,4-9H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is a metabolite of the substance Pinoxaden metabolite (NOA 447204) 8-(2,6-diethyl-4-methyl-phenyl)-8-hydroxy -tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepine-7,9-dione Not in list C18H24N2O4 CCc1cc(C)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O InChI=1S/C18H24N2O4/c1-4-13-10-12(3)11-14(5-2)15(13)18(23)16(21)19-6-8-24-9-7-20(19)17(18)22/h10-11,23H,4-9H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is a metabolite of the substance Pinoxaden metabolite (NOA 447204) 8-(2,6-diethyl-4-methyl-phenyl)-8-hydroxy -tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepine-7,9-dione Not in list C18H24N2O4 CCc1cc(C)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O InChI=1S/C18H24N2O4/c1-4-13-10-12(3)11-14(5-2)15(13)18(23)16(21)19-6-8-24-9-7-20(19)17(18)22/h10-11,23H,4-9H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is a metabolite of the substance Pinoxaden metabolite (NOA 447204) 8-(2,6-diethyl-4-methyl-phenyl)-8-hydroxy -tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepine-7,9-dione Not in list C18H24N2O4 CCc1cc(C)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O InChI=1S/C18H24N2O4/c1-4-13-10-12(3)11-14(5-2)15(13)18(23)16(21)19-6-8-24-9-7-20(19)17(18)22/h10-11,23H,4-9H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is a metabolite of the substance Pinoxaden metabolite (NOA 447204) 8-(2,6-diethyl-4-methyl-phenyl)-8-hydroxy -tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepine-7,9-dione Not in list C18H24N2O4 CCc1cc(C)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O InChI=1S/C18H24N2O4/c1-4-13-10-12(3)11-14(5-2)15(13)18(23)16(21)19-6-8-24-9-7-20(19)17(18)22/h10-11,23H,4-9H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is a metabolite of the substance Pinoxaden metabolite (NOA 447204) 8-(2,6-diethyl-4-methyl-phenyl)-8-hydroxy -tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepine-7,9-dione Not in list C18H24N2O4 CCc1cc(C)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O InChI=1S/C18H24N2O4/c1-4-13-10-12(3)11-14(5-2)15(13)18(23)16(21)19-6-8-24-9-7-20(19)17(18)22/h10-11,23H,4-9H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is a metabolite of the substance Pinoxaden metabolite (NOA 447204) 8-(2,6-diethyl-4-methyl-phenyl)-8-hydroxy -tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepine-7,9-dione Not in list C18H24N2O4 CCc1cc(C)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O InChI=1S/C18H24N2O4/c1-4-13-10-12(3)11-14(5-2)15(13)18(23)16(21)19-6-8-24-9-7-20(19)17(18)22/h10-11,23H,4-9H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is a metabolite of the substance Pinoxaden metabolite (NOA 447204) 8-(2,6-diethyl-4-methyl-phenyl)-8-hydroxy -tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepine-7,9-dione Not in list C18H24N2O4 CCc1cc(C)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O InChI=1S/C18H24N2O4/c1-4-13-10-12(3)11-14(5-2)15(13)18(23)16(21)19-6-8-24-9-7-20(19)17(18)22/h10-11,23H,4-9H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is a metabolite of the substance Pinoxaden metabolite (NOA 447204) 8-(2,6-diethyl-4-methyl-phenyl)-8-hydroxy -tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepine-7,9-dione Not in list C18H24N2O4 CCc1cc(C)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O InChI=1S/C18H24N2O4/c1-4-13-10-12(3)11-14(5-2)15(13)18(23)16(21)19-6-8-24-9-7-20(19)17(18)22/h10-11,23H,4-9H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is a metabolite of the substance Pinoxaden metabolite (NOA 447204) 8-(2,6-diethyl-4-methyl-phenyl)-8-hydroxy -tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepine-7,9-dione Not in list C18H24N2O4 CCc1cc(C)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O InChI=1S/C18H24N2O4/c1-4-13-10-12(3)11-14(5-2)15(13)18(23)16(21)19-6-8-24-9-7-20(19)17(18)22/h10-11,23H,4-9H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes without Negative RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is a metabolite of the substance Pinoxaden metabolite (NOA 447204) 8-(2,6-diethyl-4-methyl-phenyl)-8-hydroxy -tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepine-7,9-dione Not in list C18H24N2O4 CCc1cc(C)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O InChI=1S/C18H24N2O4/c1-4-13-10-12(3)11-14(5-2)15(13)18(23)16(21)19-6-8-24-9-7-20(19)17(18)22/h10-11,23H,4-9H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes with Negative RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is a metabolite of the substance Pinoxaden metabolite (NOA 447204) 8-(2,6-diethyl-4-methyl-phenyl)-8-hydroxy -tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepine-7,9-dione Not in list C18H24N2O4 CCc1cc(C)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O InChI=1S/C18H24N2O4/c1-4-13-10-12(3)11-14(5-2)15(13)18(23)16(21)19-6-8-24-9-7-20(19)17(18)22/h10-11,23H,4-9H2,1-3H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Positive RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is a metabolite of the substance Pinoxaden metabolite (NOA 447204) 8-(2,6-diethyl-4-methyl-phenyl)-8-hydroxy -tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepine-7,9-dione Not in list C18H24N2O4 CCc1cc(C)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O InChI=1S/C18H24N2O4/c1-4-13-10-12(3)11-14(5-2)15(13)18(23)16(21)19-6-8-24-9-7-20(19)17(18)22/h10-11,23H,4-9H2,1-3H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Positive RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is a metabolite of the substance Pinoxaden metabolite (NOA 447204) 8-(2,6-diethyl-4-methyl-phenyl)-8-hydroxy -tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepine-7,9-dione Not in list C18H24N2O4 CCc1cc(C)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O InChI=1S/C18H24N2O4/c1-4-13-10-12(3)11-14(5-2)15(13)18(23)16(21)19-6-8-24-9-7-20(19)17(18)22/h10-11,23H,4-9H2,1-3H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative large colonies RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is a metabolite of the substance Pinoxaden metabolite (NOA 447204) 8-(2,6-diethyl-4-methyl-phenyl)-8-hydroxy -tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepine-7,9-dione Not in list C18H24N2O4 CCc1cc(C)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O InChI=1S/C18H24N2O4/c1-4-13-10-12(3)11-14(5-2)15(13)18(23)16(21)19-6-8-24-9-7-20(19)17(18)22/h10-11,23H,4-9H2,1-3H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative large colonies RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is a metabolite of the substance Pinoxaden metabolite (NOA 447204) 8-(2,6-diethyl-4-methyl-phenyl)-8-hydroxy -tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepine-7,9-dione Not in list C18H24N2O4 CCc1cc(C)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O InChI=1S/C18H24N2O4/c1-4-13-10-12(3)11-14(5-2)15(13)18(23)16(21)19-6-8-24-9-7-20(19)17(18)22/h10-11,23H,4-9H2,1-3H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative small colonies RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is a metabolite of the substance Pinoxaden metabolite (NOA 447204) 8-(2,6-diethyl-4-methyl-phenyl)-8-hydroxy -tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepine-7,9-dione Not in list C18H24N2O4 CCc1cc(C)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O InChI=1S/C18H24N2O4/c1-4-13-10-12(3)11-14(5-2)15(13)18(23)16(21)19-6-8-24-9-7-20(19)17(18)22/h10-11,23H,4-9H2,1-3H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative small colonies RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is a metabolite of the substance Pinoxaden metabolite (NOA 447204) 8-(2,6-diethyl-4-methyl-phenyl)-8-hydroxy -tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepine-7,9-dione Not in list C18H24N2O4 CCc1cc(C)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O InChI=1S/C18H24N2O4/c1-4-13-10-12(3)11-14(5-2)15(13)18(23)16(21)19-6-8-24-9-7-20(19)17(18)22/h10-11,23H,4-9H2,1-3H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 5 Male oral: unspecified 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is a metabolite of the substance Pinoxaden metabolite (NOA 447204) 8-(2,6-diethyl-4-methyl-phenyl)-8-hydroxy -tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepine-7,9-dione Not in list C18H24N2O4 CCc1cc(C)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O InChI=1S/C18H24N2O4/c1-4-13-10-12(3)11-14(5-2)15(13)18(23)16(21)19-6-8-24-9-7-20(19)17(18)22/h10-11,23H,4-9H2,1-3H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 5 Male oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is a metabolite of the substance Pinoxaden metabolite (NOA 447204) 8-(2,6-diethyl-4-methyl-phenyl)-8-hydroxy -tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepine-7,9-dione Not in list C18H24N2O4 CCc1cc(C)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O InChI=1S/C18H24N2O4/c1-4-13-10-12(3)11-14(5-2)15(13)18(23)16(21)19-6-8-24-9-7-20(19)17(18)22/h10-11,23H,4-9H2,1-3H3 organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Alpk:APf SD Rat 3 No data oral: unspecified 16.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is a metabolite of the substance Pinoxaden metabolite (NOA 447204) 8-(2,6-diethyl-4-methyl-phenyl)-8-hydroxy -tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepine-7,9-dione Not in list C18H24N2O4 CCc1cc(C)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O InChI=1S/C18H24N2O4/c1-4-13-10-12(3)11-14(5-2)15(13)18(23)16(21)19-6-8-24-9-7-20(19)17(18)22/h10-11,23H,4-9H2,1-3H3 organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Alpk:APf SD Rat 3 No data oral: unspecified 2.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is a metabolite of the substance Pinoxaden metabolite (SYN 502836) 3,5-diethyl-4-(9-hydroxy-7-oxo-1,2,4,5-tetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepin-8-yl)benzoic acid Not in list C18H22N2O5 O=C(O)c3cc(CC)c(C=2C(=O)N1CCOCCN1C=2O)c(CC)c3 InChI=1S/C18H22N2O5/c1-3-11-9-13(18(23)24)10-12(4-2)14(11)15-16(21)19-5-7-25-8-6-20(19)17(15)22/h9-10,21H,3-8H2,1-2H3,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is a metabolite of the substance Pinoxaden metabolite (SYN 502836) 3,5-diethyl-4-(9-hydroxy-7-oxo-1,2,4,5-tetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepin-8-yl)benzoic acid Not in list C18H22N2O5 O=C(O)c3cc(CC)c(C=2C(=O)N1CCOCCN1C=2O)c(CC)c3 InChI=1S/C18H22N2O5/c1-3-11-9-13(18(23)24)10-12(4-2)14(11)15-16(21)19-5-7-25-8-6-20(19)17(15)22/h9-10,21H,3-8H2,1-2H3,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is a metabolite of the substance Pinoxaden metabolite (SYN 502836) 3,5-diethyl-4-(9-hydroxy-7-oxo-1,2,4,5-tetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepin-8-yl)benzoic acid Not in list C18H22N2O5 O=C(O)c3cc(CC)c(C=2C(=O)N1CCOCCN1C=2O)c(CC)c3 InChI=1S/C18H22N2O5/c1-3-11-9-13(18(23)24)10-12(4-2)14(11)15-16(21)19-5-7-25-8-6-20(19)17(15)22/h9-10,21H,3-8H2,1-2H3,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is a metabolite of the substance Pinoxaden metabolite (SYN 502836) 3,5-diethyl-4-(9-hydroxy-7-oxo-1,2,4,5-tetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepin-8-yl)benzoic acid Not in list C18H22N2O5 O=C(O)c3cc(CC)c(C=2C(=O)N1CCOCCN1C=2O)c(CC)c3 InChI=1S/C18H22N2O5/c1-3-11-9-13(18(23)24)10-12(4-2)14(11)15-16(21)19-5-7-25-8-6-20(19)17(15)22/h9-10,21H,3-8H2,1-2H3,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is a metabolite of the substance Pinoxaden metabolite (SYN 502836) 3,5-diethyl-4-(9-hydroxy-7-oxo-1,2,4,5-tetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepin-8-yl)benzoic acid Not in list C18H22N2O5 O=C(O)c3cc(CC)c(C=2C(=O)N1CCOCCN1C=2O)c(CC)c3 InChI=1S/C18H22N2O5/c1-3-11-9-13(18(23)24)10-12(4-2)14(11)15-16(21)19-5-7-25-8-6-20(19)17(15)22/h9-10,21H,3-8H2,1-2H3,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is a metabolite of the substance Pinoxaden metabolite (SYN 502836) 3,5-diethyl-4-(9-hydroxy-7-oxo-1,2,4,5-tetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepin-8-yl)benzoic acid Not in list C18H22N2O5 O=C(O)c3cc(CC)c(C=2C(=O)N1CCOCCN1C=2O)c(CC)c3 InChI=1S/C18H22N2O5/c1-3-11-9-13(18(23)24)10-12(4-2)14(11)15-16(21)19-5-7-25-8-6-20(19)17(15)22/h9-10,21H,3-8H2,1-2H3,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is a metabolite of the substance Pinoxaden metabolite (SYN 502836) 3,5-diethyl-4-(9-hydroxy-7-oxo-1,2,4,5-tetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepin-8-yl)benzoic acid Not in list C18H22N2O5 O=C(O)c3cc(CC)c(C=2C(=O)N1CCOCCN1C=2O)c(CC)c3 InChI=1S/C18H22N2O5/c1-3-11-9-13(18(23)24)10-12(4-2)14(11)15-16(21)19-5-7-25-8-6-20(19)17(15)22/h9-10,21H,3-8H2,1-2H3,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is a metabolite of the substance Pinoxaden metabolite (SYN 502836) 3,5-diethyl-4-(9-hydroxy-7-oxo-1,2,4,5-tetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepin-8-yl)benzoic acid Not in list C18H22N2O5 O=C(O)c3cc(CC)c(C=2C(=O)N1CCOCCN1C=2O)c(CC)c3 InChI=1S/C18H22N2O5/c1-3-11-9-13(18(23)24)10-12(4-2)14(11)15-16(21)19-5-7-25-8-6-20(19)17(15)22/h9-10,21H,3-8H2,1-2H3,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is a metabolite of the substance Pinoxaden metabolite (SYN 502836) 3,5-diethyl-4-(9-hydroxy-7-oxo-1,2,4,5-tetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepin-8-yl)benzoic acid Not in list C18H22N2O5 O=C(O)c3cc(CC)c(C=2C(=O)N1CCOCCN1C=2O)c(CC)c3 InChI=1S/C18H22N2O5/c1-3-11-9-13(18(23)24)10-12(4-2)14(11)15-16(21)19-5-7-25-8-6-20(19)17(15)22/h9-10,21H,3-8H2,1-2H3,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is a metabolite of the substance Pinoxaden metabolite (SYN 502836) 3,5-diethyl-4-(9-hydroxy-7-oxo-1,2,4,5-tetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepin-8-yl)benzoic acid Not in list C18H22N2O5 O=C(O)c3cc(CC)c(C=2C(=O)N1CCOCCN1C=2O)c(CC)c3 InChI=1S/C18H22N2O5/c1-3-11-9-13(18(23)24)10-12(4-2)14(11)15-16(21)19-5-7-25-8-6-20(19)17(15)22/h9-10,21H,3-8H2,1-2H3,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is a metabolite of the substance Pinoxaden metabolite (SYN 502836) 3,5-diethyl-4-(9-hydroxy-7-oxo-1,2,4,5-tetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepin-8-yl)benzoic acid Not in list C18H22N2O5 O=C(O)c3cc(CC)c(C=2C(=O)N1CCOCCN1C=2O)c(CC)c3 InChI=1S/C18H22N2O5/c1-3-11-9-13(18(23)24)10-12(4-2)14(11)15-16(21)19-5-7-25-8-6-20(19)17(15)22/h9-10,21H,3-8H2,1-2H3,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is a metabolite of the substance Pinoxaden metabolite (SYN 502836) 3,5-diethyl-4-(9-hydroxy-7-oxo-1,2,4,5-tetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepin-8-yl)benzoic acid Not in list C18H22N2O5 O=C(O)c3cc(CC)c(C=2C(=O)N1CCOCCN1C=2O)c(CC)c3 InChI=1S/C18H22N2O5/c1-3-11-9-13(18(23)24)10-12(4-2)14(11)15-16(21)19-5-7-25-8-6-20(19)17(15)22/h9-10,21H,3-8H2,1-2H3,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is a metabolite of the substance Pinoxaden metabolite (SYN 502836) 3,5-diethyl-4-(9-hydroxy-7-oxo-1,2,4,5-tetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepin-8-yl)benzoic acid Not in list C18H22N2O5 O=C(O)c3cc(CC)c(C=2C(=O)N1CCOCCN1C=2O)c(CC)c3 InChI=1S/C18H22N2O5/c1-3-11-9-13(18(23)24)10-12(4-2)14(11)15-16(21)19-5-7-25-8-6-20(19)17(15)22/h9-10,21H,3-8H2,1-2H3,(H,23,24) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is a metabolite of the substance Pinoxaden metabolite (SYN 502836) 3,5-diethyl-4-(9-hydroxy-7-oxo-1,2,4,5-tetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepin-8-yl)benzoic acid Not in list C18H22N2O5 O=C(O)c3cc(CC)c(C=2C(=O)N1CCOCCN1C=2O)c(CC)c3 InChI=1S/C18H22N2O5/c1-3-11-9-13(18(23)24)10-12(4-2)14(11)15-16(21)19-5-7-25-8-6-20(19)17(15)22/h9-10,21H,3-8H2,1-2H3,(H,23,24) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is a metabolite of the substance Pinoxaden metabolite (SYN 502836) 3,5-diethyl-4-(9-hydroxy-7-oxo-1,2,4,5-tetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepin-8-yl)benzoic acid Not in list C18H22N2O5 O=C(O)c3cc(CC)c(C=2C(=O)N1CCOCCN1C=2O)c(CC)c3 InChI=1S/C18H22N2O5/c1-3-11-9-13(18(23)24)10-12(4-2)14(11)15-16(21)19-5-7-25-8-6-20(19)17(15)22/h9-10,21H,3-8H2,1-2H3,(H,23,24) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative large colonies RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is a metabolite of the substance Pinoxaden metabolite (SYN 502836) 3,5-diethyl-4-(9-hydroxy-7-oxo-1,2,4,5-tetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepin-8-yl)benzoic acid Not in list C18H22N2O5 O=C(O)c3cc(CC)c(C=2C(=O)N1CCOCCN1C=2O)c(CC)c3 InChI=1S/C18H22N2O5/c1-3-11-9-13(18(23)24)10-12(4-2)14(11)15-16(21)19-5-7-25-8-6-20(19)17(15)22/h9-10,21H,3-8H2,1-2H3,(H,23,24) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative large colonies RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is a metabolite of the substance Pinoxaden metabolite (SYN 502836) 3,5-diethyl-4-(9-hydroxy-7-oxo-1,2,4,5-tetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepin-8-yl)benzoic acid Not in list C18H22N2O5 O=C(O)c3cc(CC)c(C=2C(=O)N1CCOCCN1C=2O)c(CC)c3 InChI=1S/C18H22N2O5/c1-3-11-9-13(18(23)24)10-12(4-2)14(11)15-16(21)19-5-7-25-8-6-20(19)17(15)22/h9-10,21H,3-8H2,1-2H3,(H,23,24) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative small colonies RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is a metabolite of the substance Pinoxaden metabolite (SYN 502836) 3,5-diethyl-4-(9-hydroxy-7-oxo-1,2,4,5-tetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepin-8-yl)benzoic acid Not in list C18H22N2O5 O=C(O)c3cc(CC)c(C=2C(=O)N1CCOCCN1C=2O)c(CC)c3 InChI=1S/C18H22N2O5/c1-3-11-9-13(18(23)24)10-12(4-2)14(11)15-16(21)19-5-7-25-8-6-20(19)17(15)22/h9-10,21H,3-8H2,1-2H3,(H,23,24) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative small colonies RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is a metabolite of the substance Pinoxaden metabolite (SYN 505887) 8-[2,6-diethyl-4-(hydroxymethyl)phenyl]-8-hydroxytetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepine-7,9(8H)-dione Not in list C18H24N2O5 CCc1cc(CO)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O InChI=1S/C18H24N2O5/c1-3-13-9-12(11-21)10-14(4-2)15(13)18(24)16(22)19-5-7-25-8-6-20(19)17(18)23/h9-10,21,24H,3-8,11H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is a metabolite of the substance Pinoxaden metabolite (SYN 505887) 8-[2,6-diethyl-4-(hydroxymethyl)phenyl]-8-hydroxytetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepine-7,9(8H)-dione Not in list C18H24N2O5 CCc1cc(CO)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O InChI=1S/C18H24N2O5/c1-3-13-9-12(11-21)10-14(4-2)15(13)18(24)16(22)19-5-7-25-8-6-20(19)17(18)23/h9-10,21,24H,3-8,11H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported no data without Negative RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is a metabolite of the substance Pinoxaden metabolite (SYN 505887) 8-[2,6-diethyl-4-(hydroxymethyl)phenyl]-8-hydroxytetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepine-7,9(8H)-dione Not in list C18H24N2O5 CCc1cc(CO)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O InChI=1S/C18H24N2O5/c1-3-13-9-12(11-21)10-14(4-2)15(13)18(24)16(22)19-5-7-25-8-6-20(19)17(18)23/h9-10,21,24H,3-8,11H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is a metabolite of the substance Pinoxaden metabolite (SYN 505887) 8-[2,6-diethyl-4-(hydroxymethyl)phenyl]-8-hydroxytetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepine-7,9(8H)-dione Not in list C18H24N2O5 CCc1cc(CO)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O InChI=1S/C18H24N2O5/c1-3-13-9-12(11-21)10-14(4-2)15(13)18(24)16(22)19-5-7-25-8-6-20(19)17(18)23/h9-10,21,24H,3-8,11H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported no data with Negative RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is a metabolite of the substance Pinoxaden metabolite (SYN 505887) 8-[2,6-diethyl-4-(hydroxymethyl)phenyl]-8-hydroxytetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepine-7,9(8H)-dione Not in list C18H24N2O5 CCc1cc(CO)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O InChI=1S/C18H24N2O5/c1-3-13-9-12(11-21)10-14(4-2)15(13)18(24)16(22)19-5-7-25-8-6-20(19)17(18)23/h9-10,21,24H,3-8,11H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is a metabolite of the substance Pinoxaden metabolite (SYN 505887) 8-[2,6-diethyl-4-(hydroxymethyl)phenyl]-8-hydroxytetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepine-7,9(8H)-dione Not in list C18H24N2O5 CCc1cc(CO)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O InChI=1S/C18H24N2O5/c1-3-13-9-12(11-21)10-14(4-2)15(13)18(24)16(22)19-5-7-25-8-6-20(19)17(18)23/h9-10,21,24H,3-8,11H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is a metabolite of the substance Pinoxaden metabolite (SYN 505887) 8-[2,6-diethyl-4-(hydroxymethyl)phenyl]-8-hydroxytetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepine-7,9(8H)-dione Not in list C18H24N2O5 CCc1cc(CO)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O InChI=1S/C18H24N2O5/c1-3-13-9-12(11-21)10-14(4-2)15(13)18(24)16(22)19-5-7-25-8-6-20(19)17(18)23/h9-10,21,24H,3-8,11H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is a metabolite of the substance Pinoxaden metabolite (SYN 505887) 8-[2,6-diethyl-4-(hydroxymethyl)phenyl]-8-hydroxytetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepine-7,9(8H)-dione Not in list C18H24N2O5 CCc1cc(CO)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O InChI=1S/C18H24N2O5/c1-3-13-9-12(11-21)10-14(4-2)15(13)18(24)16(22)19-5-7-25-8-6-20(19)17(18)23/h9-10,21,24H,3-8,11H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is a metabolite of the substance Pinoxaden metabolite (SYN 505887) 8-[2,6-diethyl-4-(hydroxymethyl)phenyl]-8-hydroxytetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepine-7,9(8H)-dione Not in list C18H24N2O5 CCc1cc(CO)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O InChI=1S/C18H24N2O5/c1-3-13-9-12(11-21)10-14(4-2)15(13)18(24)16(22)19-5-7-25-8-6-20(19)17(18)23/h9-10,21,24H,3-8,11H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is a metabolite of the substance Pinoxaden metabolite (SYN 505887) 8-[2,6-diethyl-4-(hydroxymethyl)phenyl]-8-hydroxytetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepine-7,9(8H)-dione Not in list C18H24N2O5 CCc1cc(CO)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O InChI=1S/C18H24N2O5/c1-3-13-9-12(11-21)10-14(4-2)15(13)18(24)16(22)19-5-7-25-8-6-20(19)17(18)23/h9-10,21,24H,3-8,11H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is a metabolite of the substance Pinoxaden metabolite (SYN 505887) 8-[2,6-diethyl-4-(hydroxymethyl)phenyl]-8-hydroxytetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepine-7,9(8H)-dione Not in list C18H24N2O5 CCc1cc(CO)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O InChI=1S/C18H24N2O5/c1-3-13-9-12(11-21)10-14(4-2)15(13)18(24)16(22)19-5-7-25-8-6-20(19)17(18)23/h9-10,21,24H,3-8,11H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is a metabolite of the substance Pinoxaden metabolite (SYN 505887) 8-[2,6-diethyl-4-(hydroxymethyl)phenyl]-8-hydroxytetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepine-7,9(8H)-dione Not in list C18H24N2O5 CCc1cc(CO)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O InChI=1S/C18H24N2O5/c1-3-13-9-12(11-21)10-14(4-2)15(13)18(24)16(22)19-5-7-25-8-6-20(19)17(18)23/h9-10,21,24H,3-8,11H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is a metabolite of the substance Pinoxaden metabolite (SYN 505887) 8-[2,6-diethyl-4-(hydroxymethyl)phenyl]-8-hydroxytetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepine-7,9(8H)-dione Not in list C18H24N2O5 CCc1cc(CO)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O InChI=1S/C18H24N2O5/c1-3-13-9-12(11-21)10-14(4-2)15(13)18(24)16(22)19-5-7-25-8-6-20(19)17(18)23/h9-10,21,24H,3-8,11H2,1-2H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is a metabolite of the substance Pinoxaden metabolite (SYN 505887) 8-[2,6-diethyl-4-(hydroxymethyl)phenyl]-8-hydroxytetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepine-7,9(8H)-dione Not in list C18H24N2O5 CCc1cc(CO)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O InChI=1S/C18H24N2O5/c1-3-13-9-12(11-21)10-14(4-2)15(13)18(24)16(22)19-5-7-25-8-6-20(19)17(18)23/h9-10,21,24H,3-8,11H2,1-2H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is a metabolite of the substance Pinoxaden metabolite (SYN 505887) 8-[2,6-diethyl-4-(hydroxymethyl)phenyl]-8-hydroxytetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepine-7,9(8H)-dione Not in list C18H24N2O5 CCc1cc(CO)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O InChI=1S/C18H24N2O5/c1-3-13-9-12(11-21)10-14(4-2)15(13)18(24)16(22)19-5-7-25-8-6-20(19)17(18)23/h9-10,21,24H,3-8,11H2,1-2H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Positive large colonies RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is a metabolite of the substance Pinoxaden metabolite (SYN 505887) 8-[2,6-diethyl-4-(hydroxymethyl)phenyl]-8-hydroxytetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepine-7,9(8H)-dione Not in list C18H24N2O5 CCc1cc(CO)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O InChI=1S/C18H24N2O5/c1-3-13-9-12(11-21)10-14(4-2)15(13)18(24)16(22)19-5-7-25-8-6-20(19)17(18)23/h9-10,21,24H,3-8,11H2,1-2H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative large colonies RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is a metabolite of the substance Pinoxaden metabolite (SYN 505887) 8-[2,6-diethyl-4-(hydroxymethyl)phenyl]-8-hydroxytetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepine-7,9(8H)-dione Not in list C18H24N2O5 CCc1cc(CO)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O InChI=1S/C18H24N2O5/c1-3-13-9-12(11-21)10-14(4-2)15(13)18(24)16(22)19-5-7-25-8-6-20(19)17(18)23/h9-10,21,24H,3-8,11H2,1-2H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative small colonies RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is a metabolite of the substance Pinoxaden metabolite (SYN 505887) 8-[2,6-diethyl-4-(hydroxymethyl)phenyl]-8-hydroxytetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepine-7,9(8H)-dione Not in list C18H24N2O5 CCc1cc(CO)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O InChI=1S/C18H24N2O5/c1-3-13-9-12(11-21)10-14(4-2)15(13)18(24)16(22)19-5-7-25-8-6-20(19)17(18)23/h9-10,21,24H,3-8,11H2,1-2H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Positive small colonies RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is a metabolite of the substance Pinoxaden metabolite (SYN 505887) 8-[2,6-diethyl-4-(hydroxymethyl)phenyl]-8-hydroxytetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepine-7,9(8H)-dione Not in list C18H24N2O5 CCc1cc(CO)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O InChI=1S/C18H24N2O5/c1-3-13-9-12(11-21)10-14(4-2)15(13)18(24)16(22)19-5-7-25-8-6-20(19)17(18)23/h9-10,21,24H,3-8,11H2,1-2H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable Rat (as animal) Alpk:APf SD Rat 35 Male oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is a metabolite of the substance Pinoxaden metabolite (SYN 505887) 8-[2,6-diethyl-4-(hydroxymethyl)phenyl]-8-hydroxytetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepine-7,9(8H)-dione Not in list C18H24N2O5 CCc1cc(CO)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O InChI=1S/C18H24N2O5/c1-3-13-9-12(11-21)10-14(4-2)15(13)18(24)16(22)19-5-7-25-8-6-20(19)17(18)23/h9-10,21,24H,3-8,11H2,1-2H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable Rat (as animal) Alpk:APf SD Rat 35 Male oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is a metabolite of the substance Pinoxaden metabolite (SYN 505887) 8-[2,6-diethyl-4-(hydroxymethyl)phenyl]-8-hydroxytetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepine-7,9(8H)-dione Not in list C18H24N2O5 CCc1cc(CO)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O InChI=1S/C18H24N2O5/c1-3-13-9-12(11-21)10-14(4-2)15(13)18(24)16(22)19-5-7-25-8-6-20(19)17(18)23/h9-10,21,24H,3-8,11H2,1-2H3 organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Alpk:APf SD Rat 3 Male oral: unspecified 16.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pinoxaden 243973-20-8 single chemical entity Component is a metabolite of the substance Pinoxaden metabolite (SYN 505887) 8-[2,6-diethyl-4-(hydroxymethyl)phenyl]-8-hydroxytetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepine-7,9(8H)-dione Not in list C18H24N2O5 CCc1cc(CO)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O InChI=1S/C18H24N2O5/c1-3-13-9-12(11-21)10-14(4-2)15(13)18(24)16(22)19-5-7-25-8-6-20(19)17(18)23/h9-10,21,24H,3-8,11H2,1-2H3 organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Alpk:APf SD Rat 3 Male oral: unspecified 2.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Pinoxaden (NOA 407855) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden. 16Aug2013 2013 doi:10.2903/j.efsa.2013.3269
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is identical to the substance Pencycuron 266-096-3 66063-05-6 1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea Pencycuron C19H21ClN2O O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1 InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is identical to the substance Pencycuron 266-096-3 66063-05-6 1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea Pencycuron C19H21ClN2O O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1 InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is identical to the substance Pencycuron 266-096-3 66063-05-6 1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea Pencycuron C19H21ClN2O O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1 InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is identical to the substance Pencycuron 266-096-3 66063-05-6 1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea Pencycuron C19H21ClN2O O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1 InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23) organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes without Negative RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is identical to the substance Pencycuron 266-096-3 66063-05-6 1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea Pencycuron C19H21ClN2O O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1 InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is identical to the substance Pencycuron 266-096-3 66063-05-6 1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea Pencycuron C19H21ClN2O O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1 InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is identical to the substance Pencycuron 266-096-3 66063-05-6 1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea Pencycuron C19H21ClN2O O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1 InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is identical to the substance Pencycuron 266-096-3 66063-05-6 1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea Pencycuron C19H21ClN2O O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1 InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is identical to the substance Pencycuron 266-096-3 66063-05-6 1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea Pencycuron C19H21ClN2O O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1 InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23) organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes without Negative RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is identical to the substance Pencycuron 266-096-3 66063-05-6 1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea Pencycuron C19H21ClN2O O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1 InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is identical to the substance Pencycuron 266-096-3 66063-05-6 1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea Pencycuron C19H21ClN2O O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1 InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is identical to the substance Pencycuron 266-096-3 66063-05-6 1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea Pencycuron C19H21ClN2O O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1 InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is identical to the substance Pencycuron 266-096-3 66063-05-6 1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea Pencycuron C19H21ClN2O O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1 InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is identical to the substance Pencycuron 266-096-3 66063-05-6 1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea Pencycuron C19H21ClN2O O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1 InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23) organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes without Negative RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is identical to the substance Pencycuron 266-096-3 66063-05-6 1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea Pencycuron C19H21ClN2O O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1 InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is identical to the substance Pencycuron 266-096-3 66063-05-6 1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea Pencycuron C19H21ClN2O O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1 InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is identical to the substance Pencycuron 266-096-3 66063-05-6 1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea Pencycuron C19H21ClN2O O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1 InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is identical to the substance Pencycuron 266-096-3 66063-05-6 1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea Pencycuron C19H21ClN2O O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1 InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is identical to the substance Pencycuron 266-096-3 66063-05-6 1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea Pencycuron C19H21ClN2O O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1 InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is identical to the substance Pencycuron 266-096-3 66063-05-6 1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea Pencycuron C19H21ClN2O O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1 InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is identical to the substance Pencycuron 266-096-3 66063-05-6 1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea Pencycuron C19H21ClN2O O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1 InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is identical to the substance Pencycuron 266-096-3 66063-05-6 1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea Pencycuron C19H21ClN2O O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1 InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is identical to the substance Pencycuron 266-096-3 66063-05-6 1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea Pencycuron C19H21ClN2O O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1 InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is identical to the substance Pencycuron 266-096-3 66063-05-6 1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea Pencycuron C19H21ClN2O O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1 InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23) organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes without Negative RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is identical to the substance Pencycuron 266-096-3 66063-05-6 1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea Pencycuron C19H21ClN2O O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1 InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23) organic compound Other Other gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) DNA-polymerase-A-proficient Not reported yes with Negative RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is identical to the substance Pencycuron 266-096-3 66063-05-6 1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea Pencycuron C19H21ClN2O O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1 InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23) organic compound Other Other gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) DNA-polymerase-A-deficient Not reported yes with Negative RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is identical to the substance Pencycuron 266-096-3 66063-05-6 1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea Pencycuron C19H21ClN2O O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1 InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23) organic compound Other Other gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) DNA-polymerase-A-proficient Not reported yes without Negative RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is identical to the substance Pencycuron 266-096-3 66063-05-6 1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea Pencycuron C19H21ClN2O O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1 InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23) organic compound Other Other gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) DNA-polymerase-A-deficient Not reported yes without Negative RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is identical to the substance Pencycuron 266-096-3 66063-05-6 1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea Pencycuron C19H21ClN2O O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1 InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23) organic compound Other Other gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Saccharomyces cerevisiae (as organism) Strain S211c S. cerevisiae Not reported no data without Negative RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is identical to the substance Pencycuron 266-096-3 66063-05-6 1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea Pencycuron C19H21ClN2O O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1 InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23) organic compound Other Other gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Saccharomyces cerevisiae (as organism) S138 Not reported no data without Negative RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is identical to the substance Pencycuron 266-096-3 66063-05-6 1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea Pencycuron C19H21ClN2O O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1 InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23) organic compound Other Other genome mutation other in vitro No guideline available Not reported Yes Acceptable Saccharomyces cerevisiae (as organism) D7 Not reported no data with Negative RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is identical to the substance Pencycuron 266-096-3 66063-05-6 1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea Pencycuron C19H21ClN2O O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1 InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23) organic compound Other Other genome mutation other in vitro No guideline available Not reported Not applicable Acceptable Saccharomyces cerevisiae (as organism) D7 Not reported no data with Negative RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is identical to the substance Pencycuron 266-096-3 66063-05-6 1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea Pencycuron C19H21ClN2O O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1 InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23) organic compound Other Other genome mutation other in vitro No guideline available Not reported Not applicable Acceptable Saccharomyces cerevisiae (as organism) D7 Not reported no data without Negative RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is identical to the substance Pencycuron 266-096-3 66063-05-6 1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea Pencycuron C19H21ClN2O O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1 InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23) organic compound Other Other genome mutation other in vitro No guideline available Not reported Yes Acceptable Saccharomyces cerevisiae (as organism) D7 Not reported no data without Negative RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is identical to the substance Pencycuron 266-096-3 66063-05-6 1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea Pencycuron C19H21ClN2O O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1 InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23) organic compound Other Other genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro Equivalent or similar to OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay) Yes Acceptable Saccharomyces cerevisiae (as organism) D7 Not reported no data with Negative RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is identical to the substance Pencycuron 266-096-3 66063-05-6 1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea Pencycuron C19H21ClN2O O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1 InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23) organic compound Other Other genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro Equivalent or similar to OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay) Yes Acceptable Saccharomyces cerevisiae (as organism) D7 Not reported no data without Negative RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is identical to the substance Pencycuron 266-096-3 66063-05-6 1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea Pencycuron C19H21ClN2O O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1 InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes without Negative RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is identical to the substance Pencycuron 266-096-3 66063-05-6 1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea Pencycuron C19H21ClN2O O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1 InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes with Negative RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is identical to the substance Pencycuron 266-096-3 66063-05-6 1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea Pencycuron C19H21ClN2O O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1 InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data without Negative RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is identical to the substance Pencycuron 266-096-3 66063-05-6 1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea Pencycuron C19H21ClN2O O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1 InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data with Negative RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is identical to the substance Pencycuron 266-096-3 66063-05-6 1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea Pencycuron C19H21ClN2O O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1 InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23) organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro No guideline followed Not reported Not applicable Acceptable Rat (as animal) hepatocytes Not reported no data without Negative RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is identical to the substance Pencycuron 266-096-3 66063-05-6 1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea Pencycuron C19H21ClN2O O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1 InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported no data without Negative RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is identical to the substance Pencycuron 266-096-3 66063-05-6 1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea Pencycuron C19H21ClN2O O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1 InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported no data with Negative RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is identical to the substance Pencycuron 266-096-3 66063-05-6 1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea Pencycuron C19H21ClN2O O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1 InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female intraperitoneal 48.0000000000 h yes not applicable Negative direct evidence-cytotoxicity$indirect evidence-systemic toxicity RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is identical to the substance Pencycuron 266-096-3 66063-05-6 1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea Pencycuron C19H21ClN2O O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1 InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female intraperitoneal 24.0000000000 h yes not applicable Negative direct evidence-cytotoxicity$indirect evidence-systemic toxicity RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is identical to the substance Pencycuron 266-096-3 66063-05-6 1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea Pencycuron C19H21ClN2O O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1 InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female intraperitoneal 72.0000000000 h yes not applicable Negative direct evidence-cytotoxicity$indirect evidence-systemic toxicity RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is identical to the substance Pencycuron 266-096-3 66063-05-6 1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea Pencycuron C19H21ClN2O O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1 InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23) organic compound Other Other chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) Yes Acceptable House mouse (as animal) NMRI Male oral: unspecified yes not applicable Negative RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is identical to the substance Pencycuron 266-096-3 66063-05-6 1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea Pencycuron C19H21ClN2O O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1 InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23) organic compound Other Other chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) Yes Acceptable House mouse (as animal) NMRI Male oral: unspecified yes not applicable Negative RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is identical to the substance Pencycuron 266-096-3 66063-05-6 1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea Pencycuron C19H21ClN2O O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1 InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is identical to the substance Pencycuron 266-096-3 66063-05-6 1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea Pencycuron C19H21ClN2O O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1 InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is identical to the substance Pencycuron 266-096-3 66063-05-6 1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea Pencycuron C19H21ClN2O O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1 InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is identical to the substance Pencycuron 266-096-3 66063-05-6 1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea Pencycuron C19H21ClN2O O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1 InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is identical to the substance Pencycuron 266-096-3 66063-05-6 1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea Pencycuron C19H21ClN2O O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1 InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is identical to the substance Pencycuron 266-096-3 66063-05-6 1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea Pencycuron C19H21ClN2O O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1 InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is identical to the substance Pencycuron 266-096-3 66063-05-6 1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea Pencycuron C19H21ClN2O O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1 InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is identical to the substance Pencycuron 266-096-3 66063-05-6 1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea Pencycuron C19H21ClN2O O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1 InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is identical to the substance Pencycuron 266-096-3 66063-05-6 1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea Pencycuron C19H21ClN2O O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1 InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is identical to the substance Pencycuron 266-096-3 66063-05-6 1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea Pencycuron C19H21ClN2O O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1 InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is a metabolite of the substance N-(4-chlorobenzyl)cyclopentanamine N-(4-chlorobenzyl)cyclopentanamine Not in list C12H16ClN Clc1ccc(cc1)CNC2CCCC2 InChI=1S/C12H16ClN/c13-11-7-5-10(6-8-11)9-14-12-3-1-2-4-12/h5-8,12,14H,1-4,9H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is a metabolite of the substance N-(4-chlorobenzyl)cyclopentanamine N-(4-chlorobenzyl)cyclopentanamine Not in list C12H16ClN Clc1ccc(cc1)CNC2CCCC2 InChI=1S/C12H16ClN/c13-11-7-5-10(6-8-11)9-14-12-3-1-2-4-12/h5-8,12,14H,1-4,9H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is a metabolite of the substance N-(4-chlorobenzyl)cyclopentanamine N-(4-chlorobenzyl)cyclopentanamine Not in list C12H16ClN Clc1ccc(cc1)CNC2CCCC2 InChI=1S/C12H16ClN/c13-11-7-5-10(6-8-11)9-14-12-3-1-2-4-12/h5-8,12,14H,1-4,9H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is a metabolite of the substance N-(4-chlorobenzyl)cyclopentanamine N-(4-chlorobenzyl)cyclopentanamine Not in list C12H16ClN Clc1ccc(cc1)CNC2CCCC2 InChI=1S/C12H16ClN/c13-11-7-5-10(6-8-11)9-14-12-3-1-2-4-12/h5-8,12,14H,1-4,9H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is a metabolite of the substance N-(4-chlorobenzyl)cyclopentanamine N-(4-chlorobenzyl)cyclopentanamine Not in list C12H16ClN Clc1ccc(cc1)CNC2CCCC2 InChI=1S/C12H16ClN/c13-11-7-5-10(6-8-11)9-14-12-3-1-2-4-12/h5-8,12,14H,1-4,9H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is a metabolite of the substance N-(4-chlorobenzyl)cyclopentanamine N-(4-chlorobenzyl)cyclopentanamine Not in list C12H16ClN Clc1ccc(cc1)CNC2CCCC2 InChI=1S/C12H16ClN/c13-11-7-5-10(6-8-11)9-14-12-3-1-2-4-12/h5-8,12,14H,1-4,9H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is a metabolite of the substance N-(4-chlorobenzyl)cyclopentanamine N-(4-chlorobenzyl)cyclopentanamine Not in list C12H16ClN Clc1ccc(cc1)CNC2CCCC2 InChI=1S/C12H16ClN/c13-11-7-5-10(6-8-11)9-14-12-3-1-2-4-12/h5-8,12,14H,1-4,9H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is a metabolite of the substance N-(4-chlorobenzyl)cyclopentanamine N-(4-chlorobenzyl)cyclopentanamine Not in list C12H16ClN Clc1ccc(cc1)CNC2CCCC2 InChI=1S/C12H16ClN/c13-11-7-5-10(6-8-11)9-14-12-3-1-2-4-12/h5-8,12,14H,1-4,9H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is a metabolite of the substance N-(4-chlorobenzyl)cyclopentanamine N-(4-chlorobenzyl)cyclopentanamine Not in list C12H16ClN Clc1ccc(cc1)CNC2CCCC2 InChI=1S/C12H16ClN/c13-11-7-5-10(6-8-11)9-14-12-3-1-2-4-12/h5-8,12,14H,1-4,9H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Pencycuron 266-096-3 66063-05-6 single chemical entity Component is a metabolite of the substance N-(4-chlorobenzyl)cyclopentanamine N-(4-chlorobenzyl)cyclopentanamine Not in list C12H16ClN Clc1ccc(cc1)CNC2CCCC2 InChI=1S/C12H16ClN/c13-11-7-5-10(6-8-11)9-14-12-3-1-2-4-12/h5-8,12,14H,1-4,9H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Pencycuron (Final Addendum to the DAR) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron 04Oct2010 2010 doi:10.2903/j.efsa.2010.1828
+Phosalone 218-996-2 2310-17-0 single chemical entity Component is identical to the substance Phosalone 218-996-2 2310-17-0 S-[(6-chloro-2-oxo-1,3-benzoxazol-3(2H)-yl)methyl] O,O-diethyl dithiophosphate Phosalone C12H15ClNO4PS2 CCOP(=S)(OCC)SCN1C(=O)Oc2cc(Cl)ccc12 InChI=1/C12H15ClNO4PS2/c1-3-16-19(20,17-4-2)21-8-14-10-6-5-9(13)7-11(10)18-12(14)15/h5-7H,3-4,8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Austria Phosalone 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone 06Mar2006 2006 doi:10.2903/j.efsa.2006.60r
+Phosalone 218-996-2 2310-17-0 single chemical entity Component is identical to the substance Phosalone 218-996-2 2310-17-0 S-[(6-chloro-2-oxo-1,3-benzoxazol-3(2H)-yl)methyl] O,O-diethyl dithiophosphate Phosalone C12H15ClNO4PS2 CCOP(=S)(OCC)SCN1C(=O)Oc2cc(Cl)ccc12 InChI=1/C12H15ClNO4PS2/c1-3-16-19(20,17-4-2)21-8-14-10-6-5-9(13)7-11(10)18-12(14)15/h5-7H,3-4,8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Austria Phosalone 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone 06Mar2006 2006 doi:10.2903/j.efsa.2006.60r
+Phosalone 218-996-2 2310-17-0 single chemical entity Component is identical to the substance Phosalone 218-996-2 2310-17-0 S-[(6-chloro-2-oxo-1,3-benzoxazol-3(2H)-yl)methyl] O,O-diethyl dithiophosphate Phosalone C12H15ClNO4PS2 CCOP(=S)(OCC)SCN1C(=O)Oc2cc(Cl)ccc12 InChI=1/C12H15ClNO4PS2/c1-3-16-19(20,17-4-2)21-8-14-10-6-5-9(13)7-11(10)18-12(14)15/h5-7H,3-4,8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Austria Phosalone 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone 06Mar2006 2006 doi:10.2903/j.efsa.2006.60r
+Phosalone 218-996-2 2310-17-0 single chemical entity Component is identical to the substance Phosalone 218-996-2 2310-17-0 S-[(6-chloro-2-oxo-1,3-benzoxazol-3(2H)-yl)methyl] O,O-diethyl dithiophosphate Phosalone C12H15ClNO4PS2 CCOP(=S)(OCC)SCN1C(=O)Oc2cc(Cl)ccc12 InChI=1/C12H15ClNO4PS2/c1-3-16-19(20,17-4-2)21-8-14-10-6-5-9(13)7-11(10)18-12(14)15/h5-7H,3-4,8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Austria Phosalone 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone 06Mar2006 2006 doi:10.2903/j.efsa.2006.60r
+Phosalone 218-996-2 2310-17-0 single chemical entity Component is identical to the substance Phosalone 218-996-2 2310-17-0 S-[(6-chloro-2-oxo-1,3-benzoxazol-3(2H)-yl)methyl] O,O-diethyl dithiophosphate Phosalone C12H15ClNO4PS2 CCOP(=S)(OCC)SCN1C(=O)Oc2cc(Cl)ccc12 InChI=1/C12H15ClNO4PS2/c1-3-16-19(20,17-4-2)21-8-14-10-6-5-9(13)7-11(10)18-12(14)15/h5-7H,3-4,8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Austria Phosalone 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone 06Mar2006 2006 doi:10.2903/j.efsa.2006.60r
+Phosalone 218-996-2 2310-17-0 single chemical entity Component is identical to the substance Phosalone 218-996-2 2310-17-0 S-[(6-chloro-2-oxo-1,3-benzoxazol-3(2H)-yl)methyl] O,O-diethyl dithiophosphate Phosalone C12H15ClNO4PS2 CCOP(=S)(OCC)SCN1C(=O)Oc2cc(Cl)ccc12 InChI=1/C12H15ClNO4PS2/c1-3-16-19(20,17-4-2)21-8-14-10-6-5-9(13)7-11(10)18-12(14)15/h5-7H,3-4,8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Austria Phosalone 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone 06Mar2006 2006 doi:10.2903/j.efsa.2006.60r
+Phosalone 218-996-2 2310-17-0 single chemical entity Component is identical to the substance Phosalone 218-996-2 2310-17-0 S-[(6-chloro-2-oxo-1,3-benzoxazol-3(2H)-yl)methyl] O,O-diethyl dithiophosphate Phosalone C12H15ClNO4PS2 CCOP(=S)(OCC)SCN1C(=O)Oc2cc(Cl)ccc12 InChI=1/C12H15ClNO4PS2/c1-3-16-19(20,17-4-2)21-8-14-10-6-5-9(13)7-11(10)18-12(14)15/h5-7H,3-4,8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Austria Phosalone 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone 06Mar2006 2006 doi:10.2903/j.efsa.2006.60r
+Phosalone 218-996-2 2310-17-0 single chemical entity Component is identical to the substance Phosalone 218-996-2 2310-17-0 S-[(6-chloro-2-oxo-1,3-benzoxazol-3(2H)-yl)methyl] O,O-diethyl dithiophosphate Phosalone C12H15ClNO4PS2 CCOP(=S)(OCC)SCN1C(=O)Oc2cc(Cl)ccc12 InChI=1/C12H15ClNO4PS2/c1-3-16-19(20,17-4-2)21-8-14-10-6-5-9(13)7-11(10)18-12(14)15/h5-7H,3-4,8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Austria Phosalone 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone 06Mar2006 2006 doi:10.2903/j.efsa.2006.60r
+Phosalone 218-996-2 2310-17-0 single chemical entity Component is identical to the substance Phosalone 218-996-2 2310-17-0 S-[(6-chloro-2-oxo-1,3-benzoxazol-3(2H)-yl)methyl] O,O-diethyl dithiophosphate Phosalone C12H15ClNO4PS2 CCOP(=S)(OCC)SCN1C(=O)Oc2cc(Cl)ccc12 InChI=1/C12H15ClNO4PS2/c1-3-16-19(20,17-4-2)21-8-14-10-6-5-9(13)7-11(10)18-12(14)15/h5-7H,3-4,8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Austria Phosalone 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone 06Mar2006 2006 doi:10.2903/j.efsa.2006.60r
+Phosalone 218-996-2 2310-17-0 single chemical entity Component is identical to the substance Phosalone 218-996-2 2310-17-0 S-[(6-chloro-2-oxo-1,3-benzoxazol-3(2H)-yl)methyl] O,O-diethyl dithiophosphate Phosalone C12H15ClNO4PS2 CCOP(=S)(OCC)SCN1C(=O)Oc2cc(Cl)ccc12 InChI=1/C12H15ClNO4PS2/c1-3-16-19(20,17-4-2)21-8-14-10-6-5-9(13)7-11(10)18-12(14)15/h5-7H,3-4,8H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Austria Phosalone 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone 06Mar2006 2006 doi:10.2903/j.efsa.2006.60r
+Phosalone 218-996-2 2310-17-0 single chemical entity Component is identical to the substance Phosalone 218-996-2 2310-17-0 S-[(6-chloro-2-oxo-1,3-benzoxazol-3(2H)-yl)methyl] O,O-diethyl dithiophosphate Phosalone C12H15ClNO4PS2 CCOP(=S)(OCC)SCN1C(=O)Oc2cc(Cl)ccc12 InChI=1/C12H15ClNO4PS2/c1-3-16-19(20,17-4-2)21-8-14-10-6-5-9(13)7-11(10)18-12(14)15/h5-7H,3-4,8H2,1-2H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No data Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: Austria Phosalone 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone 06Mar2006 2006 doi:10.2903/j.efsa.2006.60r
+Phosalone 218-996-2 2310-17-0 single chemical entity Component is identical to the substance Phosalone 218-996-2 2310-17-0 S-[(6-chloro-2-oxo-1,3-benzoxazol-3(2H)-yl)methyl] O,O-diethyl dithiophosphate Phosalone C12H15ClNO4PS2 CCOP(=S)(OCC)SCN1C(=O)Oc2cc(Cl)ccc12 InChI=1/C12H15ClNO4PS2/c1-3-16-19(20,17-4-2)21-8-14-10-6-5-9(13)7-11(10)18-12(14)15/h5-7H,3-4,8H2,1-2H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No data Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: Austria Phosalone 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone 06Mar2006 2006 doi:10.2903/j.efsa.2006.60r
+Phosalone 218-996-2 2310-17-0 single chemical entity Component is identical to the substance Phosalone 218-996-2 2310-17-0 S-[(6-chloro-2-oxo-1,3-benzoxazol-3(2H)-yl)methyl] O,O-diethyl dithiophosphate Phosalone C12H15ClNO4PS2 CCOP(=S)(OCC)SCN1C(=O)Oc2cc(Cl)ccc12 InChI=1/C12H15ClNO4PS2/c1-3-16-19(20,17-4-2)21-8-14-10-6-5-9(13)7-11(10)18-12(14)15/h5-7H,3-4,8H2,1-2H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No data Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: Austria Phosalone 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone 06Mar2006 2006 doi:10.2903/j.efsa.2006.60r
+Phosalone 218-996-2 2310-17-0 single chemical entity Component is identical to the substance Phosalone 218-996-2 2310-17-0 S-[(6-chloro-2-oxo-1,3-benzoxazol-3(2H)-yl)methyl] O,O-diethyl dithiophosphate Phosalone C12H15ClNO4PS2 CCOP(=S)(OCC)SCN1C(=O)Oc2cc(Cl)ccc12 InChI=1/C12H15ClNO4PS2/c1-3-16-19(20,17-4-2)21-8-14-10-6-5-9(13)7-11(10)18-12(14)15/h5-7H,3-4,8H2,1-2H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No data Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: Austria Phosalone 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone 06Mar2006 2006 doi:10.2903/j.efsa.2006.60r
+Phosalone 218-996-2 2310-17-0 single chemical entity Component is identical to the substance Phosalone 218-996-2 2310-17-0 S-[(6-chloro-2-oxo-1,3-benzoxazol-3(2H)-yl)methyl] O,O-diethyl dithiophosphate Phosalone C12H15ClNO4PS2 CCOP(=S)(OCC)SCN1C(=O)Oc2cc(Cl)ccc12 InChI=1/C12H15ClNO4PS2/c1-3-16-19(20,17-4-2)21-8-14-10-6-5-9(13)7-11(10)18-12(14)15/h5-7H,3-4,8H2,1-2H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No data Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: Austria Phosalone 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone 06Mar2006 2006 doi:10.2903/j.efsa.2006.60r
+Phosalone 218-996-2 2310-17-0 single chemical entity Component is identical to the substance Phosalone 218-996-2 2310-17-0 S-[(6-chloro-2-oxo-1,3-benzoxazol-3(2H)-yl)methyl] O,O-diethyl dithiophosphate Phosalone C12H15ClNO4PS2 CCOP(=S)(OCC)SCN1C(=O)Oc2cc(Cl)ccc12 InChI=1/C12H15ClNO4PS2/c1-3-16-19(20,17-4-2)21-8-14-10-6-5-9(13)7-11(10)18-12(14)15/h5-7H,3-4,8H2,1-2H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No data Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: Austria Phosalone 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone 06Mar2006 2006 doi:10.2903/j.efsa.2006.60r
+Phosalone 218-996-2 2310-17-0 single chemical entity Component is identical to the substance Phosalone 218-996-2 2310-17-0 S-[(6-chloro-2-oxo-1,3-benzoxazol-3(2H)-yl)methyl] O,O-diethyl dithiophosphate Phosalone C12H15ClNO4PS2 CCOP(=S)(OCC)SCN1C(=O)Oc2cc(Cl)ccc12 InChI=1/C12H15ClNO4PS2/c1-3-16-19(20,17-4-2)21-8-14-10-6-5-9(13)7-11(10)18-12(14)15/h5-7H,3-4,8H2,1-2H3 organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Austria Phosalone 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone 06Mar2006 2006 doi:10.2903/j.efsa.2006.60r
+Phosalone 218-996-2 2310-17-0 single chemical entity Component is identical to the substance Phosalone 218-996-2 2310-17-0 S-[(6-chloro-2-oxo-1,3-benzoxazol-3(2H)-yl)methyl] O,O-diethyl dithiophosphate Phosalone C12H15ClNO4PS2 CCOP(=S)(OCC)SCN1C(=O)Oc2cc(Cl)ccc12 InChI=1/C12H15ClNO4PS2/c1-3-16-19(20,17-4-2)21-8-14-10-6-5-9(13)7-11(10)18-12(14)15/h5-7H,3-4,8H2,1-2H3 organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No data Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Positive RMS: Austria Phosalone 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone 06Mar2006 2006 doi:10.2903/j.efsa.2006.60r
+Phosalone 218-996-2 2310-17-0 single chemical entity Component is identical to the substance Phosalone 218-996-2 2310-17-0 S-[(6-chloro-2-oxo-1,3-benzoxazol-3(2H)-yl)methyl] O,O-diethyl dithiophosphate Phosalone C12H15ClNO4PS2 CCOP(=S)(OCC)SCN1C(=O)Oc2cc(Cl)ccc12 InChI=1/C12H15ClNO4PS2/c1-3-16-19(20,17-4-2)21-8-14-10-6-5-9(13)7-11(10)18-12(14)15/h5-7H,3-4,8H2,1-2H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 4 Male/Female oral: gavage 6.0000000000 h yes, concurrent vehicle not applicable Inconclusive direct evidence-cytotoxicity RMS: Austria Phosalone 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone 06Mar2006 2006 doi:10.2903/j.efsa.2006.60r
+Phosalone 218-996-2 2310-17-0 single chemical entity Component is identical to the substance Phosalone 218-996-2 2310-17-0 S-[(6-chloro-2-oxo-1,3-benzoxazol-3(2H)-yl)methyl] O,O-diethyl dithiophosphate Phosalone C12H15ClNO4PS2 CCOP(=S)(OCC)SCN1C(=O)Oc2cc(Cl)ccc12 InChI=1/C12H15ClNO4PS2/c1-3-16-19(20,17-4-2)21-8-14-10-6-5-9(13)7-11(10)18-12(14)15/h5-7H,3-4,8H2,1-2H3 organic compound Other Other chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) No data Acceptable House mouse (as animal) CD-1 10 Male oral: gavage yes, concurrent vehicle not applicable Negative RMS: Austria Phosalone 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone 06Mar2006 2006 doi:10.2903/j.efsa.2006.60r
+Phosalone 218-996-2 2310-17-0 single chemical entity Component is a metabolite of the substance 2-amino-7-chloro-3H-phenoxazin-3-one 2-amino-7-chloro-3H-phenoxazin-3-one Not in list C12H7ClN2O2 NC1=CC2=Nc3ccc(Cl)cc3OC2=CC1=O InChI=1S/C12H7ClN2O2/c13-6-1-2-8-11(3-6)17-12-5-10(16)7(14)4-9(12)15-8/h1-5H,14H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Positive RMS: Austria Phosalone 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone 06Mar2006 2006 doi:10.2903/j.efsa.2006.60r
+Phosalone 218-996-2 2310-17-0 single chemical entity Component is a metabolite of the substance 2-amino-7-chloro-3H-phenoxazin-3-one 2-amino-7-chloro-3H-phenoxazin-3-one Not in list C12H7ClN2O2 NC1=CC2=Nc3ccc(Cl)cc3OC2=CC1=O InChI=1S/C12H7ClN2O2/c13-6-1-2-8-11(3-6)17-12-5-10(16)7(14)4-9(12)15-8/h1-5H,14H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Austria Phosalone 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone 06Mar2006 2006 doi:10.2903/j.efsa.2006.60r
+Phosalone 218-996-2 2310-17-0 single chemical entity Component is a metabolite of the substance 2-amino-7-chloro-3H-phenoxazin-3-one 2-amino-7-chloro-3H-phenoxazin-3-one Not in list C12H7ClN2O2 NC1=CC2=Nc3ccc(Cl)cc3OC2=CC1=O InChI=1S/C12H7ClN2O2/c13-6-1-2-8-11(3-6)17-12-5-10(16)7(14)4-9(12)15-8/h1-5H,14H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Austria Phosalone 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone 06Mar2006 2006 doi:10.2903/j.efsa.2006.60r
+Phosalone 218-996-2 2310-17-0 single chemical entity Component is a metabolite of the substance 2-amino-7-chloro-3H-phenoxazin-3-one 2-amino-7-chloro-3H-phenoxazin-3-one Not in list C12H7ClN2O2 NC1=CC2=Nc3ccc(Cl)cc3OC2=CC1=O InChI=1S/C12H7ClN2O2/c13-6-1-2-8-11(3-6)17-12-5-10(16)7(14)4-9(12)15-8/h1-5H,14H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Positive RMS: Austria Phosalone 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone 06Mar2006 2006 doi:10.2903/j.efsa.2006.60r
+Phosalone 218-996-2 2310-17-0 single chemical entity Component is a metabolite of the substance 2-amino-7-chloro-3H-phenoxazin-3-one 2-amino-7-chloro-3H-phenoxazin-3-one Not in list C12H7ClN2O2 NC1=CC2=Nc3ccc(Cl)cc3OC2=CC1=O InChI=1S/C12H7ClN2O2/c13-6-1-2-8-11(3-6)17-12-5-10(16)7(14)4-9(12)15-8/h1-5H,14H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Austria Phosalone 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone 06Mar2006 2006 doi:10.2903/j.efsa.2006.60r
+Phosalone 218-996-2 2310-17-0 single chemical entity Component is a metabolite of the substance 2-amino-7-chloro-3H-phenoxazin-3-one 2-amino-7-chloro-3H-phenoxazin-3-one Not in list C12H7ClN2O2 NC1=CC2=Nc3ccc(Cl)cc3OC2=CC1=O InChI=1S/C12H7ClN2O2/c13-6-1-2-8-11(3-6)17-12-5-10(16)7(14)4-9(12)15-8/h1-5H,14H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Austria Phosalone 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone 06Mar2006 2006 doi:10.2903/j.efsa.2006.60r
+Phosalone 218-996-2 2310-17-0 single chemical entity Component is a metabolite of the substance 2-amino-7-chloro-3H-phenoxazin-3-one 2-amino-7-chloro-3H-phenoxazin-3-one Not in list C12H7ClN2O2 NC1=CC2=Nc3ccc(Cl)cc3OC2=CC1=O InChI=1S/C12H7ClN2O2/c13-6-1-2-8-11(3-6)17-12-5-10(16)7(14)4-9(12)15-8/h1-5H,14H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Austria Phosalone 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone 06Mar2006 2006 doi:10.2903/j.efsa.2006.60r
+Phosalone 218-996-2 2310-17-0 single chemical entity Component is a metabolite of the substance 2-amino-7-chloro-3H-phenoxazin-3-one 2-amino-7-chloro-3H-phenoxazin-3-one Not in list C12H7ClN2O2 NC1=CC2=Nc3ccc(Cl)cc3OC2=CC1=O InChI=1S/C12H7ClN2O2/c13-6-1-2-8-11(3-6)17-12-5-10(16)7(14)4-9(12)15-8/h1-5H,14H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Austria Phosalone 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone 06Mar2006 2006 doi:10.2903/j.efsa.2006.60r
+Phosalone 218-996-2 2310-17-0 single chemical entity Component is a metabolite of the substance 2-amino-7-chloro-3H-phenoxazin-3-one 2-amino-7-chloro-3H-phenoxazin-3-one Not in list C12H7ClN2O2 NC1=CC2=Nc3ccc(Cl)cc3OC2=CC1=O InChI=1S/C12H7ClN2O2/c13-6-1-2-8-11(3-6)17-12-5-10(16)7(14)4-9(12)15-8/h1-5H,14H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Austria Phosalone 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone 06Mar2006 2006 doi:10.2903/j.efsa.2006.60r
+Phosalone 218-996-2 2310-17-0 single chemical entity Component is a metabolite of the substance 2-amino-7-chloro-3H-phenoxazin-3-one 2-amino-7-chloro-3H-phenoxazin-3-one Not in list C12H7ClN2O2 NC1=CC2=Nc3ccc(Cl)cc3OC2=CC1=O InChI=1S/C12H7ClN2O2/c13-6-1-2-8-11(3-6)17-12-5-10(16)7(14)4-9(12)15-8/h1-5H,14H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Austria Phosalone 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone 06Mar2006 2006 doi:10.2903/j.efsa.2006.60r
+Phosalone 218-996-2 2310-17-0 single chemical entity Component is a metabolite of the substance 2-amino-7-chloro-3H-phenoxazin-3-one 2-amino-7-chloro-3H-phenoxazin-3-one Not in list C12H7ClN2O2 NC1=CC2=Nc3ccc(Cl)cc3OC2=CC1=O InChI=1S/C12H7ClN2O2/c13-6-1-2-8-11(3-6)17-12-5-10(16)7(14)4-9(12)15-8/h1-5H,14H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Austria Phosalone 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone 06Mar2006 2006 doi:10.2903/j.efsa.2006.60r
+Phosalone 218-996-2 2310-17-0 single chemical entity Component is a metabolite of the substance 2-amino-7-chloro-3H-phenoxazin-3-one 2-amino-7-chloro-3H-phenoxazin-3-one Not in list C12H7ClN2O2 NC1=CC2=Nc3ccc(Cl)cc3OC2=CC1=O InChI=1S/C12H7ClN2O2/c13-6-1-2-8-11(3-6)17-12-5-10(16)7(14)4-9(12)15-8/h1-5H,14H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Austria Phosalone 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone 06Mar2006 2006 doi:10.2903/j.efsa.2006.60r
+Phosalone 218-996-2 2310-17-0 single chemical entity Component is a metabolite of the substance 2-amino-7-chloro-3H-phenoxazin-3-one 2-amino-7-chloro-3H-phenoxazin-3-one Not in list C12H7ClN2O2 NC1=CC2=Nc3ccc(Cl)cc3OC2=CC1=O InChI=1S/C12H7ClN2O2/c13-6-1-2-8-11(3-6)17-12-5-10(16)7(14)4-9(12)15-8/h1-5H,14H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Austria Phosalone 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone 06Mar2006 2006 doi:10.2903/j.efsa.2006.60r
+Phosalone 218-996-2 2310-17-0 single chemical entity Component is a metabolite of the substance 2-amino-7-chloro-3H-phenoxazin-3-one 2-amino-7-chloro-3H-phenoxazin-3-one Not in list C12H7ClN2O2 NC1=CC2=Nc3ccc(Cl)cc3OC2=CC1=O InChI=1S/C12H7ClN2O2/c13-6-1-2-8-11(3-6)17-12-5-10(16)7(14)4-9(12)15-8/h1-5H,14H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Austria Phosalone 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone 06Mar2006 2006 doi:10.2903/j.efsa.2006.60r
+Phosalone 218-996-2 2310-17-0 single chemical entity Component is a metabolite of the substance 2-amino-7-chloro-3H-phenoxazin-3-one 2-amino-7-chloro-3H-phenoxazin-3-one Not in list C12H7ClN2O2 NC1=CC2=Nc3ccc(Cl)cc3OC2=CC1=O InChI=1S/C12H7ClN2O2/c13-6-1-2-8-11(3-6)17-12-5-10(16)7(14)4-9(12)15-8/h1-5H,14H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Austria Phosalone 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone 06Mar2006 2006 doi:10.2903/j.efsa.2006.60r
+Phosalone 218-996-2 2310-17-0 single chemical entity Component is a metabolite of the substance 2-amino-7-chloro-3H-phenoxazin-3-one 2-amino-7-chloro-3H-phenoxazin-3-one Not in list C12H7ClN2O2 NC1=CC2=Nc3ccc(Cl)cc3OC2=CC1=O InChI=1S/C12H7ClN2O2/c13-6-1-2-8-11(3-6)17-12-5-10(16)7(14)4-9(12)15-8/h1-5H,14H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Austria Phosalone 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone 06Mar2006 2006 doi:10.2903/j.efsa.2006.60r
+Phosalone 218-996-2 2310-17-0 single chemical entity Component is a metabolite of the substance 2-amino-7-chloro-3H-phenoxazin-3-one 2-amino-7-chloro-3H-phenoxazin-3-one Not in list C12H7ClN2O2 NC1=CC2=Nc3ccc(Cl)cc3OC2=CC1=O InChI=1S/C12H7ClN2O2/c13-6-1-2-8-11(3-6)17-12-5-10(16)7(14)4-9(12)15-8/h1-5H,14H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Austria Phosalone 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone 06Mar2006 2006 doi:10.2903/j.efsa.2006.60r
+Phosalone 218-996-2 2310-17-0 single chemical entity Component is a metabolite of the substance 2-amino-7-chloro-3H-phenoxazin-3-one 2-amino-7-chloro-3H-phenoxazin-3-one Not in list C12H7ClN2O2 NC1=CC2=Nc3ccc(Cl)cc3OC2=CC1=O InChI=1S/C12H7ClN2O2/c13-6-1-2-8-11(3-6)17-12-5-10(16)7(14)4-9(12)15-8/h1-5H,14H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Austria Phosalone 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone 06Mar2006 2006 doi:10.2903/j.efsa.2006.60r
+Phosalone 218-996-2 2310-17-0 single chemical entity Component is a metabolite of the substance 2-amino-7-chloro-3H-phenoxazin-3-one 2-amino-7-chloro-3H-phenoxazin-3-one Not in list C12H7ClN2O2 NC1=CC2=Nc3ccc(Cl)cc3OC2=CC1=O InChI=1S/C12H7ClN2O2/c13-6-1-2-8-11(3-6)17-12-5-10(16)7(14)4-9(12)15-8/h1-5H,14H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Positive RMS: Austria Phosalone 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone 06Mar2006 2006 doi:10.2903/j.efsa.2006.60r
+Phosalone 218-996-2 2310-17-0 single chemical entity Component is a metabolite of the substance 2-amino-7-chloro-3H-phenoxazin-3-one 2-amino-7-chloro-3H-phenoxazin-3-one Not in list C12H7ClN2O2 NC1=CC2=Nc3ccc(Cl)cc3OC2=CC1=O InChI=1S/C12H7ClN2O2/c13-6-1-2-8-11(3-6)17-12-5-10(16)7(14)4-9(12)15-8/h1-5H,14H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Austria Phosalone 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone 06Mar2006 2006 doi:10.2903/j.efsa.2006.60r
+Phosalone 218-996-2 2310-17-0 single chemical entity Component is a metabolite of the substance 2-amino-7-chloro-3H-phenoxazin-3-one 2-amino-7-chloro-3H-phenoxazin-3-one Not in list C12H7ClN2O2 NC1=CC2=Nc3ccc(Cl)cc3OC2=CC1=O InChI=1S/C12H7ClN2O2/c13-6-1-2-8-11(3-6)17-12-5-10(16)7(14)4-9(12)15-8/h1-5H,14H2 organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Wistar 4 Male oral: gavage 4.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Austria Phosalone 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone 06Mar2006 2006 doi:10.2903/j.efsa.2006.60r
+Phosalone 218-996-2 2310-17-0 single chemical entity Component is a metabolite of the substance 2-amino-7-chloro-3H-phenoxazin-3-one 2-amino-7-chloro-3H-phenoxazin-3-one Not in list C12H7ClN2O2 NC1=CC2=Nc3ccc(Cl)cc3OC2=CC1=O InChI=1S/C12H7ClN2O2/c13-6-1-2-8-11(3-6)17-12-5-10(16)7(14)4-9(12)15-8/h1-5H,14H2 organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Wistar 4 Male oral: gavage 14.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Austria Phosalone 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone 06Mar2006 2006 doi:10.2903/j.efsa.2006.60r
+Penflufen 494793-67-8 single chemical entity Component is identical to the substance Penflufen 494793-67-8 5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide Not in list C18H24FN3O O=C(Nc1ccccc1C(C)CC(C)C)c2c(F)n(C)nc2C InChI=1S/C18H24FN3O/c1-11(2)10-12(3)14-8-6-7-9-15(14)20-18(23)16-13(4)21-22(5)17(16)19/h6-9,11-12H,10H2,1-5H3,(H,20,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Penflufen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen 21Aug2012 2012 doi:10.2903/j.efsa.2012.2860
+Penflufen 494793-67-8 single chemical entity Component is identical to the substance Penflufen 494793-67-8 5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide Not in list C18H24FN3O O=C(Nc1ccccc1C(C)CC(C)C)c2c(F)n(C)nc2C InChI=1S/C18H24FN3O/c1-11(2)10-12(3)14-8-6-7-9-15(14)20-18(23)16-13(4)21-22(5)17(16)19/h6-9,11-12H,10H2,1-5H3,(H,20,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Penflufen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen 21Aug2012 2012 doi:10.2903/j.efsa.2012.2860
+Penflufen 494793-67-8 single chemical entity Component is identical to the substance Penflufen 494793-67-8 5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide Not in list C18H24FN3O O=C(Nc1ccccc1C(C)CC(C)C)c2c(F)n(C)nc2C InChI=1S/C18H24FN3O/c1-11(2)10-12(3)14-8-6-7-9-15(14)20-18(23)16-13(4)21-22(5)17(16)19/h6-9,11-12H,10H2,1-5H3,(H,20,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Penflufen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen 21Aug2012 2012 doi:10.2903/j.efsa.2012.2860
+Penflufen 494793-67-8 single chemical entity Component is identical to the substance Penflufen 494793-67-8 5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide Not in list C18H24FN3O O=C(Nc1ccccc1C(C)CC(C)C)c2c(F)n(C)nc2C InChI=1S/C18H24FN3O/c1-11(2)10-12(3)14-8-6-7-9-15(14)20-18(23)16-13(4)21-22(5)17(16)19/h6-9,11-12H,10H2,1-5H3,(H,20,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Penflufen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen 21Aug2012 2012 doi:10.2903/j.efsa.2012.2860
+Penflufen 494793-67-8 single chemical entity Component is identical to the substance Penflufen 494793-67-8 5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide Not in list C18H24FN3O O=C(Nc1ccccc1C(C)CC(C)C)c2c(F)n(C)nc2C InChI=1S/C18H24FN3O/c1-11(2)10-12(3)14-8-6-7-9-15(14)20-18(23)16-13(4)21-22(5)17(16)19/h6-9,11-12H,10H2,1-5H3,(H,20,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Penflufen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen 21Aug2012 2012 doi:10.2903/j.efsa.2012.2860
+Penflufen 494793-67-8 single chemical entity Component is identical to the substance Penflufen 494793-67-8 5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide Not in list C18H24FN3O O=C(Nc1ccccc1C(C)CC(C)C)c2c(F)n(C)nc2C InChI=1S/C18H24FN3O/c1-11(2)10-12(3)14-8-6-7-9-15(14)20-18(23)16-13(4)21-22(5)17(16)19/h6-9,11-12H,10H2,1-5H3,(H,20,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Penflufen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen 21Aug2012 2012 doi:10.2903/j.efsa.2012.2860
+Penflufen 494793-67-8 single chemical entity Component is identical to the substance Penflufen 494793-67-8 5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide Not in list C18H24FN3O O=C(Nc1ccccc1C(C)CC(C)C)c2c(F)n(C)nc2C InChI=1S/C18H24FN3O/c1-11(2)10-12(3)14-8-6-7-9-15(14)20-18(23)16-13(4)21-22(5)17(16)19/h6-9,11-12H,10H2,1-5H3,(H,20,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Penflufen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen 21Aug2012 2012 doi:10.2903/j.efsa.2012.2860
+Penflufen 494793-67-8 single chemical entity Component is identical to the substance Penflufen 494793-67-8 5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide Not in list C18H24FN3O O=C(Nc1ccccc1C(C)CC(C)C)c2c(F)n(C)nc2C InChI=1S/C18H24FN3O/c1-11(2)10-12(3)14-8-6-7-9-15(14)20-18(23)16-13(4)21-22(5)17(16)19/h6-9,11-12H,10H2,1-5H3,(H,20,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Penflufen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen 21Aug2012 2012 doi:10.2903/j.efsa.2012.2860
+Penflufen 494793-67-8 single chemical entity Component is identical to the substance Penflufen 494793-67-8 5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide Not in list C18H24FN3O O=C(Nc1ccccc1C(C)CC(C)C)c2c(F)n(C)nc2C InChI=1S/C18H24FN3O/c1-11(2)10-12(3)14-8-6-7-9-15(14)20-18(23)16-13(4)21-22(5)17(16)19/h6-9,11-12H,10H2,1-5H3,(H,20,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Penflufen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen 21Aug2012 2012 doi:10.2903/j.efsa.2012.2860
+Penflufen 494793-67-8 single chemical entity Component is identical to the substance Penflufen 494793-67-8 5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide Not in list C18H24FN3O O=C(Nc1ccccc1C(C)CC(C)C)c2c(F)n(C)nc2C InChI=1S/C18H24FN3O/c1-11(2)10-12(3)14-8-6-7-9-15(14)20-18(23)16-13(4)21-22(5)17(16)19/h6-9,11-12H,10H2,1-5H3,(H,20,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Penflufen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen 21Aug2012 2012 doi:10.2903/j.efsa.2012.2860
+Penflufen 494793-67-8 single chemical entity Component is identical to the substance Penflufen 494793-67-8 5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide Not in list C18H24FN3O O=C(Nc1ccccc1C(C)CC(C)C)c2c(F)n(C)nc2C InChI=1S/C18H24FN3O/c1-11(2)10-12(3)14-8-6-7-9-15(14)20-18(23)16-13(4)21-22(5)17(16)19/h6-9,11-12H,10H2,1-5H3,(H,20,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Penflufen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen 21Aug2012 2012 doi:10.2903/j.efsa.2012.2860
+Penflufen 494793-67-8 single chemical entity Component is identical to the substance Penflufen 494793-67-8 5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide Not in list C18H24FN3O O=C(Nc1ccccc1C(C)CC(C)C)c2c(F)n(C)nc2C InChI=1S/C18H24FN3O/c1-11(2)10-12(3)14-8-6-7-9-15(14)20-18(23)16-13(4)21-22(5)17(16)19/h6-9,11-12H,10H2,1-5H3,(H,20,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Penflufen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen 21Aug2012 2012 doi:10.2903/j.efsa.2012.2860
+Penflufen 494793-67-8 single chemical entity Component is identical to the substance Penflufen 494793-67-8 5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide Not in list C18H24FN3O O=C(Nc1ccccc1C(C)CC(C)C)c2c(F)n(C)nc2C InChI=1S/C18H24FN3O/c1-11(2)10-12(3)14-8-6-7-9-15(14)20-18(23)16-13(4)21-22(5)17(16)19/h6-9,11-12H,10H2,1-5H3,(H,20,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Penflufen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen 21Aug2012 2012 doi:10.2903/j.efsa.2012.2860
+Penflufen 494793-67-8 single chemical entity Component is identical to the substance Penflufen 494793-67-8 5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide Not in list C18H24FN3O O=C(Nc1ccccc1C(C)CC(C)C)c2c(F)n(C)nc2C InChI=1S/C18H24FN3O/c1-11(2)10-12(3)14-8-6-7-9-15(14)20-18(23)16-13(4)21-22(5)17(16)19/h6-9,11-12H,10H2,1-5H3,(H,20,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Penflufen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen 21Aug2012 2012 doi:10.2903/j.efsa.2012.2860
+Penflufen 494793-67-8 single chemical entity Component is identical to the substance Penflufen 494793-67-8 5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide Not in list C18H24FN3O O=C(Nc1ccccc1C(C)CC(C)C)c2c(F)n(C)nc2C InChI=1S/C18H24FN3O/c1-11(2)10-12(3)14-8-6-7-9-15(14)20-18(23)16-13(4)21-22(5)17(16)19/h6-9,11-12H,10H2,1-5H3,(H,20,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Penflufen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen 21Aug2012 2012 doi:10.2903/j.efsa.2012.2860
+Penflufen 494793-67-8 single chemical entity Component is identical to the substance Penflufen 494793-67-8 5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide Not in list C18H24FN3O O=C(Nc1ccccc1C(C)CC(C)C)c2c(F)n(C)nc2C InChI=1S/C18H24FN3O/c1-11(2)10-12(3)14-8-6-7-9-15(14)20-18(23)16-13(4)21-22(5)17(16)19/h6-9,11-12H,10H2,1-5H3,(H,20,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Penflufen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen 21Aug2012 2012 doi:10.2903/j.efsa.2012.2860
+Penflufen 494793-67-8 single chemical entity Component is identical to the substance Penflufen 494793-67-8 5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide Not in list C18H24FN3O O=C(Nc1ccccc1C(C)CC(C)C)c2c(F)n(C)nc2C InChI=1S/C18H24FN3O/c1-11(2)10-12(3)14-8-6-7-9-15(14)20-18(23)16-13(4)21-22(5)17(16)19/h6-9,11-12H,10H2,1-5H3,(H,20,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Penflufen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen 21Aug2012 2012 doi:10.2903/j.efsa.2012.2860
+Penflufen 494793-67-8 single chemical entity Component is identical to the substance Penflufen 494793-67-8 5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide Not in list C18H24FN3O O=C(Nc1ccccc1C(C)CC(C)C)c2c(F)n(C)nc2C InChI=1S/C18H24FN3O/c1-11(2)10-12(3)14-8-6-7-9-15(14)20-18(23)16-13(4)21-22(5)17(16)19/h6-9,11-12H,10H2,1-5H3,(H,20,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Penflufen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen 21Aug2012 2012 doi:10.2903/j.efsa.2012.2860
+Penflufen 494793-67-8 single chemical entity Component is identical to the substance Penflufen 494793-67-8 5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide Not in list C18H24FN3O O=C(Nc1ccccc1C(C)CC(C)C)c2c(F)n(C)nc2C InChI=1S/C18H24FN3O/c1-11(2)10-12(3)14-8-6-7-9-15(14)20-18(23)16-13(4)21-22(5)17(16)19/h6-9,11-12H,10H2,1-5H3,(H,20,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Penflufen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen 21Aug2012 2012 doi:10.2903/j.efsa.2012.2860
+Penflufen 494793-67-8 single chemical entity Component is identical to the substance Penflufen 494793-67-8 5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide Not in list C18H24FN3O O=C(Nc1ccccc1C(C)CC(C)C)c2c(F)n(C)nc2C InChI=1S/C18H24FN3O/c1-11(2)10-12(3)14-8-6-7-9-15(14)20-18(23)16-13(4)21-22(5)17(16)19/h6-9,11-12H,10H2,1-5H3,(H,20,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Penflufen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen 21Aug2012 2012 doi:10.2903/j.efsa.2012.2860
+Penflufen 494793-67-8 single chemical entity Component is identical to the substance Penflufen 494793-67-8 5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide Not in list C18H24FN3O O=C(Nc1ccccc1C(C)CC(C)C)c2c(F)n(C)nc2C InChI=1S/C18H24FN3O/c1-11(2)10-12(3)14-8-6-7-9-15(14)20-18(23)16-13(4)21-22(5)17(16)19/h6-9,11-12H,10H2,1-5H3,(H,20,23) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Penflufen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen 21Aug2012 2012 doi:10.2903/j.efsa.2012.2860
+Penflufen 494793-67-8 single chemical entity Component is identical to the substance Penflufen 494793-67-8 5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide Not in list C18H24FN3O O=C(Nc1ccccc1C(C)CC(C)C)c2c(F)n(C)nc2C InChI=1S/C18H24FN3O/c1-11(2)10-12(3)14-8-6-7-9-15(14)20-18(23)16-13(4)21-22(5)17(16)19/h6-9,11-12H,10H2,1-5H3,(H,20,23) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Penflufen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen 21Aug2012 2012 doi:10.2903/j.efsa.2012.2860
+Penflufen 494793-67-8 single chemical entity Component is identical to the substance Penflufen 494793-67-8 5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide Not in list C18H24FN3O O=C(Nc1ccccc1C(C)CC(C)C)c2c(F)n(C)nc2C InChI=1S/C18H24FN3O/c1-11(2)10-12(3)14-8-6-7-9-15(14)20-18(23)16-13(4)21-22(5)17(16)19/h6-9,11-12H,10H2,1-5H3,(H,20,23) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Penflufen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen 21Aug2012 2012 doi:10.2903/j.efsa.2012.2860
+Penflufen 494793-67-8 single chemical entity Component is identical to the substance Penflufen 494793-67-8 5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide Not in list C18H24FN3O O=C(Nc1ccccc1C(C)CC(C)C)c2c(F)n(C)nc2C InChI=1S/C18H24FN3O/c1-11(2)10-12(3)14-8-6-7-9-15(14)20-18(23)16-13(4)21-22(5)17(16)19/h6-9,11-12H,10H2,1-5H3,(H,20,23) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Penflufen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen 21Aug2012 2012 doi:10.2903/j.efsa.2012.2860
+Penflufen 494793-67-8 single chemical entity Component is identical to the substance Penflufen 494793-67-8 5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide Not in list C18H24FN3O O=C(Nc1ccccc1C(C)CC(C)C)c2c(F)n(C)nc2C InChI=1S/C18H24FN3O/c1-11(2)10-12(3)14-8-6-7-9-15(14)20-18(23)16-13(4)21-22(5)17(16)19/h6-9,11-12H,10H2,1-5H3,(H,20,23) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Negative RMS: The United Kingdom Penflufen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen 21Aug2012 2012 doi:10.2903/j.efsa.2012.2860
+Penflufen 494793-67-8 single chemical entity Component is identical to the substance Penflufen 494793-67-8 5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide Not in list C18H24FN3O O=C(Nc1ccccc1C(C)CC(C)C)c2c(F)n(C)nc2C InChI=1S/C18H24FN3O/c1-11(2)10-12(3)14-8-6-7-9-15(14)20-18(23)16-13(4)21-22(5)17(16)19/h6-9,11-12H,10H2,1-5H3,(H,20,23) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Negative RMS: The United Kingdom Penflufen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen 21Aug2012 2012 doi:10.2903/j.efsa.2012.2860
+Penflufen 494793-67-8 single chemical entity Component is identical to the substance Penflufen 494793-67-8 5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide Not in list C18H24FN3O O=C(Nc1ccccc1C(C)CC(C)C)c2c(F)n(C)nc2C InChI=1S/C18H24FN3O/c1-11(2)10-12(3)14-8-6-7-9-15(14)20-18(23)16-13(4)21-22(5)17(16)19/h6-9,11-12H,10H2,1-5H3,(H,20,23) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Penflufen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen 21Aug2012 2012 doi:10.2903/j.efsa.2012.2860
+Penflufen 494793-67-8 single chemical entity Component is identical to the substance Penflufen 494793-67-8 5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide Not in list C18H24FN3O O=C(Nc1ccccc1C(C)CC(C)C)c2c(F)n(C)nc2C InChI=1S/C18H24FN3O/c1-11(2)10-12(3)14-8-6-7-9-15(14)20-18(23)16-13(4)21-22(5)17(16)19/h6-9,11-12H,10H2,1-5H3,(H,20,23) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Penflufen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen 21Aug2012 2012 doi:10.2903/j.efsa.2012.2860
+Penflufen 494793-67-8 single chemical entity Component is identical to the substance Penflufen 494793-67-8 5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide Not in list C18H24FN3O O=C(Nc1ccccc1C(C)CC(C)C)c2c(F)n(C)nc2C InChI=1S/C18H24FN3O/c1-11(2)10-12(3)14-8-6-7-9-15(14)20-18(23)16-13(4)21-22(5)17(16)19/h6-9,11-12H,10H2,1-5H3,(H,20,23) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 5 Male intraperitoneal 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: The United Kingdom Penflufen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen 21Aug2012 2012 doi:10.2903/j.efsa.2012.2860
+Penflufen 494793-67-8 single chemical entity Component is a metabolite of the substance 5-fluoro-N-[2-(3-hydroxy-1,3-dimethylbutyl)phenyl]-1,3-dimethyl-1H-pyrazole-4-carboxamide 5-fluoro-N-[2-(4-hydroxy-4-methylpentan-2-yl)phenyl]-1,3-dimethyl-1H-pyrazole-4-carboxamide Not in list C18H24FN3O2 O=C(Nc1ccccc1C(C)CC(C)(C)O)c2c(F)n(C)nc2C InChI=1S/C18H24FN3O2/c1-11(10-18(3,4)24)13-8-6-7-9-14(13)20-17(23)15-12(2)21-22(5)16(15)19/h6-9,11,24H,10H2,1-5H3,(H,20,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Penflufen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen 21Aug2012 2012 doi:10.2903/j.efsa.2012.2860
+Penflufen 494793-67-8 single chemical entity Component is a metabolite of the substance 5-fluoro-N-[2-(3-hydroxy-1,3-dimethylbutyl)phenyl]-1,3-dimethyl-1H-pyrazole-4-carboxamide 5-fluoro-N-[2-(4-hydroxy-4-methylpentan-2-yl)phenyl]-1,3-dimethyl-1H-pyrazole-4-carboxamide Not in list C18H24FN3O2 O=C(Nc1ccccc1C(C)CC(C)(C)O)c2c(F)n(C)nc2C InChI=1S/C18H24FN3O2/c1-11(10-18(3,4)24)13-8-6-7-9-14(13)20-17(23)15-12(2)21-22(5)16(15)19/h6-9,11,24H,10H2,1-5H3,(H,20,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Penflufen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen 21Aug2012 2012 doi:10.2903/j.efsa.2012.2860
+Penflufen 494793-67-8 single chemical entity Component is a metabolite of the substance 5-fluoro-N-[2-(3-hydroxy-1,3-dimethylbutyl)phenyl]-1,3-dimethyl-1H-pyrazole-4-carboxamide 5-fluoro-N-[2-(4-hydroxy-4-methylpentan-2-yl)phenyl]-1,3-dimethyl-1H-pyrazole-4-carboxamide Not in list C18H24FN3O2 O=C(Nc1ccccc1C(C)CC(C)(C)O)c2c(F)n(C)nc2C InChI=1S/C18H24FN3O2/c1-11(10-18(3,4)24)13-8-6-7-9-14(13)20-17(23)15-12(2)21-22(5)16(15)19/h6-9,11,24H,10H2,1-5H3,(H,20,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Penflufen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen 21Aug2012 2012 doi:10.2903/j.efsa.2012.2860
+Penflufen 494793-67-8 single chemical entity Component is a metabolite of the substance 5-fluoro-N-[2-(3-hydroxy-1,3-dimethylbutyl)phenyl]-1,3-dimethyl-1H-pyrazole-4-carboxamide 5-fluoro-N-[2-(4-hydroxy-4-methylpentan-2-yl)phenyl]-1,3-dimethyl-1H-pyrazole-4-carboxamide Not in list C18H24FN3O2 O=C(Nc1ccccc1C(C)CC(C)(C)O)c2c(F)n(C)nc2C InChI=1S/C18H24FN3O2/c1-11(10-18(3,4)24)13-8-6-7-9-14(13)20-17(23)15-12(2)21-22(5)16(15)19/h6-9,11,24H,10H2,1-5H3,(H,20,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Penflufen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen 21Aug2012 2012 doi:10.2903/j.efsa.2012.2860
+Penflufen 494793-67-8 single chemical entity Component is a metabolite of the substance 5-fluoro-N-[2-(3-hydroxy-1,3-dimethylbutyl)phenyl]-1,3-dimethyl-1H-pyrazole-4-carboxamide 5-fluoro-N-[2-(4-hydroxy-4-methylpentan-2-yl)phenyl]-1,3-dimethyl-1H-pyrazole-4-carboxamide Not in list C18H24FN3O2 O=C(Nc1ccccc1C(C)CC(C)(C)O)c2c(F)n(C)nc2C InChI=1S/C18H24FN3O2/c1-11(10-18(3,4)24)13-8-6-7-9-14(13)20-17(23)15-12(2)21-22(5)16(15)19/h6-9,11,24H,10H2,1-5H3,(H,20,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Penflufen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen 21Aug2012 2012 doi:10.2903/j.efsa.2012.2860
+Penflufen 494793-67-8 single chemical entity Component is a metabolite of the substance 5-fluoro-N-[2-(3-hydroxy-1,3-dimethylbutyl)phenyl]-1,3-dimethyl-1H-pyrazole-4-carboxamide 5-fluoro-N-[2-(4-hydroxy-4-methylpentan-2-yl)phenyl]-1,3-dimethyl-1H-pyrazole-4-carboxamide Not in list C18H24FN3O2 O=C(Nc1ccccc1C(C)CC(C)(C)O)c2c(F)n(C)nc2C InChI=1S/C18H24FN3O2/c1-11(10-18(3,4)24)13-8-6-7-9-14(13)20-17(23)15-12(2)21-22(5)16(15)19/h6-9,11,24H,10H2,1-5H3,(H,20,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Penflufen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen 21Aug2012 2012 doi:10.2903/j.efsa.2012.2860
+Penflufen 494793-67-8 single chemical entity Component is a metabolite of the substance 5-fluoro-N-[2-(3-hydroxy-1,3-dimethylbutyl)phenyl]-1,3-dimethyl-1H-pyrazole-4-carboxamide 5-fluoro-N-[2-(4-hydroxy-4-methylpentan-2-yl)phenyl]-1,3-dimethyl-1H-pyrazole-4-carboxamide Not in list C18H24FN3O2 O=C(Nc1ccccc1C(C)CC(C)(C)O)c2c(F)n(C)nc2C InChI=1S/C18H24FN3O2/c1-11(10-18(3,4)24)13-8-6-7-9-14(13)20-17(23)15-12(2)21-22(5)16(15)19/h6-9,11,24H,10H2,1-5H3,(H,20,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Penflufen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen 21Aug2012 2012 doi:10.2903/j.efsa.2012.2860
+Penflufen 494793-67-8 single chemical entity Component is a metabolite of the substance 5-fluoro-N-[2-(3-hydroxy-1,3-dimethylbutyl)phenyl]-1,3-dimethyl-1H-pyrazole-4-carboxamide 5-fluoro-N-[2-(4-hydroxy-4-methylpentan-2-yl)phenyl]-1,3-dimethyl-1H-pyrazole-4-carboxamide Not in list C18H24FN3O2 O=C(Nc1ccccc1C(C)CC(C)(C)O)c2c(F)n(C)nc2C InChI=1S/C18H24FN3O2/c1-11(10-18(3,4)24)13-8-6-7-9-14(13)20-17(23)15-12(2)21-22(5)16(15)19/h6-9,11,24H,10H2,1-5H3,(H,20,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Penflufen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen 21Aug2012 2012 doi:10.2903/j.efsa.2012.2860
+Penflufen 494793-67-8 single chemical entity Component is a metabolite of the substance 5-fluoro-N-[2-(3-hydroxy-1,3-dimethylbutyl)phenyl]-1,3-dimethyl-1H-pyrazole-4-carboxamide 5-fluoro-N-[2-(4-hydroxy-4-methylpentan-2-yl)phenyl]-1,3-dimethyl-1H-pyrazole-4-carboxamide Not in list C18H24FN3O2 O=C(Nc1ccccc1C(C)CC(C)(C)O)c2c(F)n(C)nc2C InChI=1S/C18H24FN3O2/c1-11(10-18(3,4)24)13-8-6-7-9-14(13)20-17(23)15-12(2)21-22(5)16(15)19/h6-9,11,24H,10H2,1-5H3,(H,20,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Penflufen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen 21Aug2012 2012 doi:10.2903/j.efsa.2012.2860
+Penflufen 494793-67-8 single chemical entity Component is a metabolite of the substance 5-fluoro-N-[2-(3-hydroxy-1,3-dimethylbutyl)phenyl]-1,3-dimethyl-1H-pyrazole-4-carboxamide 5-fluoro-N-[2-(4-hydroxy-4-methylpentan-2-yl)phenyl]-1,3-dimethyl-1H-pyrazole-4-carboxamide Not in list C18H24FN3O2 O=C(Nc1ccccc1C(C)CC(C)(C)O)c2c(F)n(C)nc2C InChI=1S/C18H24FN3O2/c1-11(10-18(3,4)24)13-8-6-7-9-14(13)20-17(23)15-12(2)21-22(5)16(15)19/h6-9,11,24H,10H2,1-5H3,(H,20,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Penflufen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen 21Aug2012 2012 doi:10.2903/j.efsa.2012.2860
+Penflufen 494793-67-8 single chemical entity Component is a metabolite of the substance 5-fluoro-N-[2-(3-hydroxy-1,3-dimethylbutyl)phenyl]-1,3-dimethyl-1H-pyrazole-4-carboxamide 5-fluoro-N-[2-(4-hydroxy-4-methylpentan-2-yl)phenyl]-1,3-dimethyl-1H-pyrazole-4-carboxamide Not in list C18H24FN3O2 O=C(Nc1ccccc1C(C)CC(C)(C)O)c2c(F)n(C)nc2C InChI=1S/C18H24FN3O2/c1-11(10-18(3,4)24)13-8-6-7-9-14(13)20-17(23)15-12(2)21-22(5)16(15)19/h6-9,11,24H,10H2,1-5H3,(H,20,23) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Penflufen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen 21Aug2012 2012 doi:10.2903/j.efsa.2012.2860
+Penflufen 494793-67-8 single chemical entity Component is a metabolite of the substance 5-fluoro-N-[2-(3-hydroxy-1,3-dimethylbutyl)phenyl]-1,3-dimethyl-1H-pyrazole-4-carboxamide 5-fluoro-N-[2-(4-hydroxy-4-methylpentan-2-yl)phenyl]-1,3-dimethyl-1H-pyrazole-4-carboxamide Not in list C18H24FN3O2 O=C(Nc1ccccc1C(C)CC(C)(C)O)c2c(F)n(C)nc2C InChI=1S/C18H24FN3O2/c1-11(10-18(3,4)24)13-8-6-7-9-14(13)20-17(23)15-12(2)21-22(5)16(15)19/h6-9,11,24H,10H2,1-5H3,(H,20,23) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Penflufen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen 21Aug2012 2012 doi:10.2903/j.efsa.2012.2860
+Penflufen 494793-67-8 single chemical entity Component is a metabolite of the substance 5-fluoro-N-[2-(3-hydroxy-1,3-dimethylbutyl)phenyl]-1,3-dimethyl-1H-pyrazole-4-carboxamide 5-fluoro-N-[2-(4-hydroxy-4-methylpentan-2-yl)phenyl]-1,3-dimethyl-1H-pyrazole-4-carboxamide Not in list C18H24FN3O2 O=C(Nc1ccccc1C(C)CC(C)(C)O)c2c(F)n(C)nc2C InChI=1S/C18H24FN3O2/c1-11(10-18(3,4)24)13-8-6-7-9-14(13)20-17(23)15-12(2)21-22(5)16(15)19/h6-9,11,24H,10H2,1-5H3,(H,20,23) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: The United Kingdom Penflufen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen 21Aug2012 2012 doi:10.2903/j.efsa.2012.2860
+Penflufen 494793-67-8 single chemical entity Component is a metabolite of the substance 5-fluoro-N-[2-(3-hydroxy-1,3-dimethylbutyl)phenyl]-1,3-dimethyl-1H-pyrazole-4-carboxamide 5-fluoro-N-[2-(4-hydroxy-4-methylpentan-2-yl)phenyl]-1,3-dimethyl-1H-pyrazole-4-carboxamide Not in list C18H24FN3O2 O=C(Nc1ccccc1C(C)CC(C)(C)O)c2c(F)n(C)nc2C InChI=1S/C18H24FN3O2/c1-11(10-18(3,4)24)13-8-6-7-9-14(13)20-17(23)15-12(2)21-22(5)16(15)19/h6-9,11,24H,10H2,1-5H3,(H,20,23) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Negative RMS: The United Kingdom Penflufen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen 21Aug2012 2012 doi:10.2903/j.efsa.2012.2860
+Penflufen 494793-67-8 single chemical entity Component is a metabolite of the substance N-(2-acetylphenyl)-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide N-(2-acetylphenyl)-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide Not in list C14H14FN3O2 O=C(Nc1ccccc1C(C)=O)c2c(F)n(C)nc2C InChI=1S/C14H14FN3O2/c1-8-12(13(15)18(3)17-8)14(20)16-11-7-5-4-6-10(11)9(2)19/h4-7H,1-3H3,(H,16,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Penflufen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen 21Aug2012 2012 doi:10.2903/j.efsa.2012.2860
+Penflufen 494793-67-8 single chemical entity Component is a metabolite of the substance N-(2-acetylphenyl)-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide N-(2-acetylphenyl)-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide Not in list C14H14FN3O2 O=C(Nc1ccccc1C(C)=O)c2c(F)n(C)nc2C InChI=1S/C14H14FN3O2/c1-8-12(13(15)18(3)17-8)14(20)16-11-7-5-4-6-10(11)9(2)19/h4-7H,1-3H3,(H,16,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Penflufen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen 21Aug2012 2012 doi:10.2903/j.efsa.2012.2860
+Penflufen 494793-67-8 single chemical entity Component is a metabolite of the substance N-(2-acetylphenyl)-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide N-(2-acetylphenyl)-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide Not in list C14H14FN3O2 O=C(Nc1ccccc1C(C)=O)c2c(F)n(C)nc2C InChI=1S/C14H14FN3O2/c1-8-12(13(15)18(3)17-8)14(20)16-11-7-5-4-6-10(11)9(2)19/h4-7H,1-3H3,(H,16,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Penflufen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen 21Aug2012 2012 doi:10.2903/j.efsa.2012.2860
+Penflufen 494793-67-8 single chemical entity Component is a metabolite of the substance N-(2-acetylphenyl)-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide N-(2-acetylphenyl)-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide Not in list C14H14FN3O2 O=C(Nc1ccccc1C(C)=O)c2c(F)n(C)nc2C InChI=1S/C14H14FN3O2/c1-8-12(13(15)18(3)17-8)14(20)16-11-7-5-4-6-10(11)9(2)19/h4-7H,1-3H3,(H,16,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Penflufen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen 21Aug2012 2012 doi:10.2903/j.efsa.2012.2860
+Penflufen 494793-67-8 single chemical entity Component is a metabolite of the substance N-(2-acetylphenyl)-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide N-(2-acetylphenyl)-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide Not in list C14H14FN3O2 O=C(Nc1ccccc1C(C)=O)c2c(F)n(C)nc2C InChI=1S/C14H14FN3O2/c1-8-12(13(15)18(3)17-8)14(20)16-11-7-5-4-6-10(11)9(2)19/h4-7H,1-3H3,(H,16,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Penflufen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen 21Aug2012 2012 doi:10.2903/j.efsa.2012.2860
+Penflufen 494793-67-8 single chemical entity Component is a metabolite of the substance N-(2-acetylphenyl)-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide N-(2-acetylphenyl)-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide Not in list C14H14FN3O2 O=C(Nc1ccccc1C(C)=O)c2c(F)n(C)nc2C InChI=1S/C14H14FN3O2/c1-8-12(13(15)18(3)17-8)14(20)16-11-7-5-4-6-10(11)9(2)19/h4-7H,1-3H3,(H,16,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Penflufen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen 21Aug2012 2012 doi:10.2903/j.efsa.2012.2860
+Penflufen 494793-67-8 single chemical entity Component is a metabolite of the substance N-(2-acetylphenyl)-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide N-(2-acetylphenyl)-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide Not in list C14H14FN3O2 O=C(Nc1ccccc1C(C)=O)c2c(F)n(C)nc2C InChI=1S/C14H14FN3O2/c1-8-12(13(15)18(3)17-8)14(20)16-11-7-5-4-6-10(11)9(2)19/h4-7H,1-3H3,(H,16,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Penflufen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen 21Aug2012 2012 doi:10.2903/j.efsa.2012.2860
+Penflufen 494793-67-8 single chemical entity Component is a metabolite of the substance N-(2-acetylphenyl)-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide N-(2-acetylphenyl)-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide Not in list C14H14FN3O2 O=C(Nc1ccccc1C(C)=O)c2c(F)n(C)nc2C InChI=1S/C14H14FN3O2/c1-8-12(13(15)18(3)17-8)14(20)16-11-7-5-4-6-10(11)9(2)19/h4-7H,1-3H3,(H,16,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Penflufen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen 21Aug2012 2012 doi:10.2903/j.efsa.2012.2860
+Penflufen 494793-67-8 single chemical entity Component is a metabolite of the substance N-(2-acetylphenyl)-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide N-(2-acetylphenyl)-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide Not in list C14H14FN3O2 O=C(Nc1ccccc1C(C)=O)c2c(F)n(C)nc2C InChI=1S/C14H14FN3O2/c1-8-12(13(15)18(3)17-8)14(20)16-11-7-5-4-6-10(11)9(2)19/h4-7H,1-3H3,(H,16,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Penflufen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen 21Aug2012 2012 doi:10.2903/j.efsa.2012.2860
+Penflufen 494793-67-8 single chemical entity Component is a metabolite of the substance N-(2-acetylphenyl)-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide N-(2-acetylphenyl)-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide Not in list C14H14FN3O2 O=C(Nc1ccccc1C(C)=O)c2c(F)n(C)nc2C InChI=1S/C14H14FN3O2/c1-8-12(13(15)18(3)17-8)14(20)16-11-7-5-4-6-10(11)9(2)19/h4-7H,1-3H3,(H,16,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Penflufen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen 21Aug2012 2012 doi:10.2903/j.efsa.2012.2860
+Penflufen 494793-67-8 single chemical entity Component is a metabolite of the substance N-(2-acetylphenyl)-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide N-(2-acetylphenyl)-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide Not in list C14H14FN3O2 O=C(Nc1ccccc1C(C)=O)c2c(F)n(C)nc2C InChI=1S/C14H14FN3O2/c1-8-12(13(15)18(3)17-8)14(20)16-11-7-5-4-6-10(11)9(2)19/h4-7H,1-3H3,(H,16,20) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Penflufen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen 21Aug2012 2012 doi:10.2903/j.efsa.2012.2860
+Penflufen 494793-67-8 single chemical entity Component is a metabolite of the substance N-(2-acetylphenyl)-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide N-(2-acetylphenyl)-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide Not in list C14H14FN3O2 O=C(Nc1ccccc1C(C)=O)c2c(F)n(C)nc2C InChI=1S/C14H14FN3O2/c1-8-12(13(15)18(3)17-8)14(20)16-11-7-5-4-6-10(11)9(2)19/h4-7H,1-3H3,(H,16,20) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Penflufen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen 21Aug2012 2012 doi:10.2903/j.efsa.2012.2860
+Penflufen 494793-67-8 single chemical entity Component is a metabolite of the substance N-(2-acetylphenyl)-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide N-(2-acetylphenyl)-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide Not in list C14H14FN3O2 O=C(Nc1ccccc1C(C)=O)c2c(F)n(C)nc2C InChI=1S/C14H14FN3O2/c1-8-12(13(15)18(3)17-8)14(20)16-11-7-5-4-6-10(11)9(2)19/h4-7H,1-3H3,(H,16,20) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Penflufen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen 21Aug2012 2012 doi:10.2903/j.efsa.2012.2860
+Penflufen 494793-67-8 single chemical entity Component is a metabolite of the substance N-(2-acetylphenyl)-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide N-(2-acetylphenyl)-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide Not in list C14H14FN3O2 O=C(Nc1ccccc1C(C)=O)c2c(F)n(C)nc2C InChI=1S/C14H14FN3O2/c1-8-12(13(15)18(3)17-8)14(20)16-11-7-5-4-6-10(11)9(2)19/h4-7H,1-3H3,(H,16,20) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Penflufen 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen 21Aug2012 2012 doi:10.2903/j.efsa.2012.2860
+Oxyfluorfen 255-983-0 42874-03-3 single chemical entity Component is identical to the substance Oxyfluorfen 255-983-0 42874-03-3 2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene Oxyfluorfen C15H11ClF3NO4 Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Spain Oxyfluorfen 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen 23Nov2010 2010 doi:10.2903/j.efsa.2010.1906
+Oxyfluorfen 255-983-0 42874-03-3 single chemical entity Component is identical to the substance Oxyfluorfen 255-983-0 42874-03-3 2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene Oxyfluorfen C15H11ClF3NO4 Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Spain Oxyfluorfen 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen 23Nov2010 2010 doi:10.2903/j.efsa.2010.1906
+Oxyfluorfen 255-983-0 42874-03-3 single chemical entity Component is identical to the substance Oxyfluorfen 255-983-0 42874-03-3 2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene Oxyfluorfen C15H11ClF3NO4 Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Spain Oxyfluorfen 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen 23Nov2010 2010 doi:10.2903/j.efsa.2010.1906
+Oxyfluorfen 255-983-0 42874-03-3 single chemical entity Component is identical to the substance Oxyfluorfen 255-983-0 42874-03-3 2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene Oxyfluorfen C15H11ClF3NO4 Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Spain Oxyfluorfen 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen 23Nov2010 2010 doi:10.2903/j.efsa.2010.1906
+Oxyfluorfen 255-983-0 42874-03-3 single chemical entity Component is identical to the substance Oxyfluorfen 255-983-0 42874-03-3 2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene Oxyfluorfen C15H11ClF3NO4 Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Spain Oxyfluorfen 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen 23Nov2010 2010 doi:10.2903/j.efsa.2010.1906
+Oxyfluorfen 255-983-0 42874-03-3 single chemical entity Component is identical to the substance Oxyfluorfen 255-983-0 42874-03-3 2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene Oxyfluorfen C15H11ClF3NO4 Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Spain Oxyfluorfen 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen 23Nov2010 2010 doi:10.2903/j.efsa.2010.1906
+Oxyfluorfen 255-983-0 42874-03-3 single chemical entity Component is identical to the substance Oxyfluorfen 255-983-0 42874-03-3 2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene Oxyfluorfen C15H11ClF3NO4 Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Spain Oxyfluorfen 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen 23Nov2010 2010 doi:10.2903/j.efsa.2010.1906
+Oxyfluorfen 255-983-0 42874-03-3 single chemical entity Component is identical to the substance Oxyfluorfen 255-983-0 42874-03-3 2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene Oxyfluorfen C15H11ClF3NO4 Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Spain Oxyfluorfen 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen 23Nov2010 2010 doi:10.2903/j.efsa.2010.1906
+Oxyfluorfen 255-983-0 42874-03-3 single chemical entity Component is identical to the substance Oxyfluorfen 255-983-0 42874-03-3 2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene Oxyfluorfen C15H11ClF3NO4 Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Spain Oxyfluorfen 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen 23Nov2010 2010 doi:10.2903/j.efsa.2010.1906
+Oxyfluorfen 255-983-0 42874-03-3 single chemical entity Component is identical to the substance Oxyfluorfen 255-983-0 42874-03-3 2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene Oxyfluorfen C15H11ClF3NO4 Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Spain Oxyfluorfen 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen 23Nov2010 2010 doi:10.2903/j.efsa.2010.1906
+Oxyfluorfen 255-983-0 42874-03-3 single chemical entity Component is identical to the substance Oxyfluorfen 255-983-0 42874-03-3 2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene Oxyfluorfen C15H11ClF3NO4 Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Spain Oxyfluorfen 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen 23Nov2010 2010 doi:10.2903/j.efsa.2010.1906
+Oxyfluorfen 255-983-0 42874-03-3 single chemical entity Component is identical to the substance Oxyfluorfen 255-983-0 42874-03-3 2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene Oxyfluorfen C15H11ClF3NO4 Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Spain Oxyfluorfen 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen 23Nov2010 2010 doi:10.2903/j.efsa.2010.1906
+Oxyfluorfen 255-983-0 42874-03-3 single chemical entity Component is identical to the substance Oxyfluorfen 255-983-0 42874-03-3 2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene Oxyfluorfen C15H11ClF3NO4 Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Spain Oxyfluorfen 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen 23Nov2010 2010 doi:10.2903/j.efsa.2010.1906
+Oxyfluorfen 255-983-0 42874-03-3 single chemical entity Component is identical to the substance Oxyfluorfen 255-983-0 42874-03-3 2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene Oxyfluorfen C15H11ClF3NO4 Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Spain Oxyfluorfen 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen 23Nov2010 2010 doi:10.2903/j.efsa.2010.1906
+Oxyfluorfen 255-983-0 42874-03-3 single chemical entity Component is identical to the substance Oxyfluorfen 255-983-0 42874-03-3 2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene Oxyfluorfen C15H11ClF3NO4 Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Spain Oxyfluorfen 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen 23Nov2010 2010 doi:10.2903/j.efsa.2010.1906
+Oxyfluorfen 255-983-0 42874-03-3 single chemical entity Component is identical to the substance Oxyfluorfen 255-983-0 42874-03-3 2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene Oxyfluorfen C15H11ClF3NO4 Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Spain Oxyfluorfen 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen 23Nov2010 2010 doi:10.2903/j.efsa.2010.1906
+Oxyfluorfen 255-983-0 42874-03-3 single chemical entity Component is identical to the substance Oxyfluorfen 255-983-0 42874-03-3 2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene Oxyfluorfen C15H11ClF3NO4 Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Spain Oxyfluorfen 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen 23Nov2010 2010 doi:10.2903/j.efsa.2010.1906
+Oxyfluorfen 255-983-0 42874-03-3 single chemical entity Component is identical to the substance Oxyfluorfen 255-983-0 42874-03-3 2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene Oxyfluorfen C15H11ClF3NO4 Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Spain Oxyfluorfen 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen 23Nov2010 2010 doi:10.2903/j.efsa.2010.1906
+Oxyfluorfen 255-983-0 42874-03-3 single chemical entity Component is identical to the substance Oxyfluorfen 255-983-0 42874-03-3 2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene Oxyfluorfen C15H11ClF3NO4 Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Spain Oxyfluorfen 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen 23Nov2010 2010 doi:10.2903/j.efsa.2010.1906
+Oxyfluorfen 255-983-0 42874-03-3 single chemical entity Component is identical to the substance Oxyfluorfen 255-983-0 42874-03-3 2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene Oxyfluorfen C15H11ClF3NO4 Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Spain Oxyfluorfen 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen 23Nov2010 2010 doi:10.2903/j.efsa.2010.1906
+Oxyfluorfen 255-983-0 42874-03-3 single chemical entity Component is identical to the substance Oxyfluorfen 255-983-0 42874-03-3 2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene Oxyfluorfen C15H11ClF3NO4 Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Spain Oxyfluorfen 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen 23Nov2010 2010 doi:10.2903/j.efsa.2010.1906
+Oxyfluorfen 255-983-0 42874-03-3 single chemical entity Component is identical to the substance Oxyfluorfen 255-983-0 42874-03-3 2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene Oxyfluorfen C15H11ClF3NO4 Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Spain Oxyfluorfen 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen 23Nov2010 2010 doi:10.2903/j.efsa.2010.1906
+Oxyfluorfen 255-983-0 42874-03-3 single chemical entity Component is identical to the substance Oxyfluorfen 255-983-0 42874-03-3 2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene Oxyfluorfen C15H11ClF3NO4 Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Spain Oxyfluorfen 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen 23Nov2010 2010 doi:10.2903/j.efsa.2010.1906
+Oxyfluorfen 255-983-0 42874-03-3 single chemical entity Component is identical to the substance Oxyfluorfen 255-983-0 42874-03-3 2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene Oxyfluorfen C15H11ClF3NO4 Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Spain Oxyfluorfen 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen 23Nov2010 2010 doi:10.2903/j.efsa.2010.1906
+Oxyfluorfen 255-983-0 42874-03-3 single chemical entity Component is identical to the substance Oxyfluorfen 255-983-0 42874-03-3 2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene Oxyfluorfen C15H11ClF3NO4 Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Spain Oxyfluorfen 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen 23Nov2010 2010 doi:10.2903/j.efsa.2010.1906
+Oxyfluorfen 255-983-0 42874-03-3 single chemical entity Component is identical to the substance Oxyfluorfen 255-983-0 42874-03-3 2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene Oxyfluorfen C15H11ClF3NO4 Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Spain Oxyfluorfen 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen 23Nov2010 2010 doi:10.2903/j.efsa.2010.1906
+Oxyfluorfen 255-983-0 42874-03-3 single chemical entity Component is identical to the substance Oxyfluorfen 255-983-0 42874-03-3 2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene Oxyfluorfen C15H11ClF3NO4 Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Spain Oxyfluorfen 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen 23Nov2010 2010 doi:10.2903/j.efsa.2010.1906
+Oxyfluorfen 255-983-0 42874-03-3 single chemical entity Component is identical to the substance Oxyfluorfen 255-983-0 42874-03-3 2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene Oxyfluorfen C15H11ClF3NO4 Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Spain Oxyfluorfen 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen 23Nov2010 2010 doi:10.2903/j.efsa.2010.1906
+Oxyfluorfen 255-983-0 42874-03-3 single chemical entity Component is identical to the substance Oxyfluorfen 255-983-0 42874-03-3 2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene Oxyfluorfen C15H11ClF3NO4 Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Spain Oxyfluorfen 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen 23Nov2010 2010 doi:10.2903/j.efsa.2010.1906
+Oxyfluorfen 255-983-0 42874-03-3 single chemical entity Component is identical to the substance Oxyfluorfen 255-983-0 42874-03-3 2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene Oxyfluorfen C15H11ClF3NO4 Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Spain Oxyfluorfen 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen 23Nov2010 2010 doi:10.2903/j.efsa.2010.1906
+Oxyfluorfen 255-983-0 42874-03-3 single chemical entity Component is identical to the substance Oxyfluorfen 255-983-0 42874-03-3 2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene Oxyfluorfen C15H11ClF3NO4 Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Spain Oxyfluorfen 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen 23Nov2010 2010 doi:10.2903/j.efsa.2010.1906
+Oxyfluorfen 255-983-0 42874-03-3 single chemical entity Component is identical to the substance Oxyfluorfen 255-983-0 42874-03-3 2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene Oxyfluorfen C15H11ClF3NO4 Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Spain Oxyfluorfen 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen 23Nov2010 2010 doi:10.2903/j.efsa.2010.1906
+Oxyfluorfen 255-983-0 42874-03-3 single chemical entity Component is identical to the substance Oxyfluorfen 255-983-0 42874-03-3 2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene Oxyfluorfen C15H11ClF3NO4 Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Spain Oxyfluorfen 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen 23Nov2010 2010 doi:10.2903/j.efsa.2010.1906
+Oxyfluorfen 255-983-0 42874-03-3 single chemical entity Component is identical to the substance Oxyfluorfen 255-983-0 42874-03-3 2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene Oxyfluorfen C15H11ClF3NO4 Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Spain Oxyfluorfen 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen 23Nov2010 2010 doi:10.2903/j.efsa.2010.1906
+Oxyfluorfen 255-983-0 42874-03-3 single chemical entity Component is identical to the substance Oxyfluorfen 255-983-0 42874-03-3 2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene Oxyfluorfen C15H11ClF3NO4 Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Spain Oxyfluorfen 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen 23Nov2010 2010 doi:10.2903/j.efsa.2010.1906
+Oxyfluorfen 255-983-0 42874-03-3 single chemical entity Component is identical to the substance Oxyfluorfen 255-983-0 42874-03-3 2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene Oxyfluorfen C15H11ClF3NO4 Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Positive RMS: Spain Oxyfluorfen 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen 23Nov2010 2010 doi:10.2903/j.efsa.2010.1906
+Oxyfluorfen 255-983-0 42874-03-3 single chemical entity Component is identical to the substance Oxyfluorfen 255-983-0 42874-03-3 2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene Oxyfluorfen C15H11ClF3NO4 Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: Spain Oxyfluorfen 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen 23Nov2010 2010 doi:10.2903/j.efsa.2010.1906
+Oxyfluorfen 255-983-0 42874-03-3 single chemical entity Component is identical to the substance Oxyfluorfen 255-983-0 42874-03-3 2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene Oxyfluorfen C15H11ClF3NO4 Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: Spain Oxyfluorfen 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen 23Nov2010 2010 doi:10.2903/j.efsa.2010.1906
+Oxyfluorfen 255-983-0 42874-03-3 single chemical entity Component is identical to the substance Oxyfluorfen 255-983-0 42874-03-3 2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene Oxyfluorfen C15H11ClF3NO4 Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Negative no information RMS: Spain Oxyfluorfen 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen 23Nov2010 2010 doi:10.2903/j.efsa.2010.1906
+Oxyfluorfen 255-983-0 42874-03-3 single chemical entity Component is identical to the substance Oxyfluorfen 255-983-0 42874-03-3 2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene Oxyfluorfen C15H11ClF3NO4 Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative no information RMS: Spain Oxyfluorfen 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen 23Nov2010 2010 doi:10.2903/j.efsa.2010.1906
+Oxyfluorfen 255-983-0 42874-03-3 single chemical entity Component is identical to the substance Oxyfluorfen 255-983-0 42874-03-3 2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene Oxyfluorfen C15H11ClF3NO4 Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Spain Oxyfluorfen 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen 23Nov2010 2010 doi:10.2903/j.efsa.2010.1906
+Oxyfluorfen 255-983-0 42874-03-3 single chemical entity Component is identical to the substance Oxyfluorfen 255-983-0 42874-03-3 2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene Oxyfluorfen C15H11ClF3NO4 Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Spain Oxyfluorfen 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen 23Nov2010 2010 doi:10.2903/j.efsa.2010.1906
+Oxyfluorfen 255-983-0 42874-03-3 single chemical entity Component is identical to the substance Oxyfluorfen 255-983-0 42874-03-3 2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene Oxyfluorfen C15H11ClF3NO4 Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3 organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes, concurrent vehicle with Negative RMS: Spain Oxyfluorfen 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen 23Nov2010 2010 doi:10.2903/j.efsa.2010.1906
+Oxyfluorfen 255-983-0 42874-03-3 single chemical entity Component is identical to the substance Oxyfluorfen 255-983-0 42874-03-3 2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene Oxyfluorfen C15H11ClF3NO4 Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3 organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes, concurrent vehicle with Negative RMS: Spain Oxyfluorfen 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen 23Nov2010 2010 doi:10.2903/j.efsa.2010.1906
+Oxyfluorfen 255-983-0 42874-03-3 single chemical entity Component is identical to the substance Oxyfluorfen 255-983-0 42874-03-3 2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene Oxyfluorfen C15H11ClF3NO4 Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3 organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes, concurrent vehicle without Negative RMS: Spain Oxyfluorfen 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen 23Nov2010 2010 doi:10.2903/j.efsa.2010.1906
+Oxyfluorfen 255-983-0 42874-03-3 single chemical entity Component is identical to the substance Oxyfluorfen 255-983-0 42874-03-3 2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene Oxyfluorfen C15H11ClF3NO4 Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3 organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes, concurrent vehicle without Negative RMS: Spain Oxyfluorfen 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen 23Nov2010 2010 doi:10.2903/j.efsa.2010.1906
+Oxyfluorfen 255-983-0 42874-03-3 single chemical entity Component is identical to the substance Oxyfluorfen 255-983-0 42874-03-3 2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene Oxyfluorfen C15H11ClF3NO4 Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) CD-1 60 Male/Female oral: gavage 51.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Spain Oxyfluorfen 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen 23Nov2010 2010 doi:10.2903/j.efsa.2010.1906
+Oxyfluorfen 255-983-0 42874-03-3 single chemical entity Component is identical to the substance Oxyfluorfen 255-983-0 42874-03-3 2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene Oxyfluorfen C15H11ClF3NO4 Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) CD-1 60 Male/Female oral: gavage 27.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Spain Oxyfluorfen 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen 23Nov2010 2010 doi:10.2903/j.efsa.2010.1906
+Oxyfluorfen 255-983-0 42874-03-3 single chemical entity Component is identical to the substance Oxyfluorfen 255-983-0 42874-03-3 2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene Oxyfluorfen C15H11ClF3NO4 Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) CD-1 60 Male/Female oral: gavage 6.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Spain Oxyfluorfen 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen 23Nov2010 2010 doi:10.2903/j.efsa.2010.1906
+Oxyfluorfen 255-983-0 42874-03-3 single chemical entity Component is identical to the substance Oxyfluorfen 255-983-0 42874-03-3 2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene Oxyfluorfen C15H11ClF3NO4 Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 20 Male/Female intraperitoneal 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Spain Oxyfluorfen 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen 23Nov2010 2010 doi:10.2903/j.efsa.2010.1906
+Oxyfluorfen 255-983-0 42874-03-3 single chemical entity Component is identical to the substance Oxyfluorfen 255-983-0 42874-03-3 2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene Oxyfluorfen C15H11ClF3NO4 Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 20 Male/Female intraperitoneal 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Spain Oxyfluorfen 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen 23Nov2010 2010 doi:10.2903/j.efsa.2010.1906
+Oxyfluorfen 255-983-0 42874-03-3 single chemical entity Component is identical to the substance Oxyfluorfen 255-983-0 42874-03-3 2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene Oxyfluorfen C15H11ClF3NO4 Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3 organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo Equivalent or similar to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) Yes Acceptable Rat (as animal) Sprague-Dawley 10 Male oral: gavage 16.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Spain Oxyfluorfen 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen 23Nov2010 2010 doi:10.2903/j.efsa.2010.1906
+Oxyfluorfen 255-983-0 42874-03-3 single chemical entity Component is identical to the substance Oxyfluorfen 255-983-0 42874-03-3 2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene Oxyfluorfen C15H11ClF3NO4 Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3 organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo Equivalent or similar to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) Yes Acceptable Rat (as animal) Sprague-Dawley 10 Male oral: gavage 2.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Spain Oxyfluorfen 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen 23Nov2010 2010 doi:10.2903/j.efsa.2010.1906
+Paclobutrazol 76738-62-0 single chemical entity Component is identical to the substance Paclobutrazol 76738-62-0 1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pentan-3-ol Paclobutrazol C15H20ClN3O OC(C(C)(C)C)C(CC(C=C1)=CC=C1Cl)N2N=CN=C2 InChI=1S/C15H20ClN3O/c1-15(2,3)14(20)13(19-10-17-9-18-19)8-11-4-6-12(16)7-5-11/h4-7,9-10,13-14,20H,8H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: The United Kingdom Paclobutrazol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol 04Nov2010 2010 doi:10.2903/j.efsa.2010.1876
+Paclobutrazol 76738-62-0 single chemical entity Component is identical to the substance Paclobutrazol 76738-62-0 1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pentan-3-ol Paclobutrazol C15H20ClN3O OC(C(C)(C)C)C(CC(C=C1)=CC=C1Cl)N2N=CN=C2 InChI=1S/C15H20ClN3O/c1-15(2,3)14(20)13(19-10-17-9-18-19)8-11-4-6-12(16)7-5-11/h4-7,9-10,13-14,20H,8H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: The United Kingdom Paclobutrazol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol 04Nov2010 2010 doi:10.2903/j.efsa.2010.1876
+Paclobutrazol 76738-62-0 single chemical entity Component is identical to the substance Paclobutrazol 76738-62-0 1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pentan-3-ol Paclobutrazol C15H20ClN3O OC(C(C)(C)C)C(CC(C=C1)=CC=C1Cl)N2N=CN=C2 InChI=1S/C15H20ClN3O/c1-15(2,3)14(20)13(19-10-17-9-18-19)8-11-4-6-12(16)7-5-11/h4-7,9-10,13-14,20H,8H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: The United Kingdom Paclobutrazol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol 04Nov2010 2010 doi:10.2903/j.efsa.2010.1876
+Paclobutrazol 76738-62-0 single chemical entity Component is identical to the substance Paclobutrazol 76738-62-0 1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pentan-3-ol Paclobutrazol C15H20ClN3O OC(C(C)(C)C)C(CC(C=C1)=CC=C1Cl)N2N=CN=C2 InChI=1S/C15H20ClN3O/c1-15(2,3)14(20)13(19-10-17-9-18-19)8-11-4-6-12(16)7-5-11/h4-7,9-10,13-14,20H,8H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: The United Kingdom Paclobutrazol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol 04Nov2010 2010 doi:10.2903/j.efsa.2010.1876
+Paclobutrazol 76738-62-0 single chemical entity Component is identical to the substance Paclobutrazol 76738-62-0 1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pentan-3-ol Paclobutrazol C15H20ClN3O OC(C(C)(C)C)C(CC(C=C1)=CC=C1Cl)N2N=CN=C2 InChI=1S/C15H20ClN3O/c1-15(2,3)14(20)13(19-10-17-9-18-19)8-11-4-6-12(16)7-5-11/h4-7,9-10,13-14,20H,8H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: The United Kingdom Paclobutrazol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol 04Nov2010 2010 doi:10.2903/j.efsa.2010.1876
+Paclobutrazol 76738-62-0 single chemical entity Component is identical to the substance Paclobutrazol 76738-62-0 1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pentan-3-ol Paclobutrazol C15H20ClN3O OC(C(C)(C)C)C(CC(C=C1)=CC=C1Cl)N2N=CN=C2 InChI=1S/C15H20ClN3O/c1-15(2,3)14(20)13(19-10-17-9-18-19)8-11-4-6-12(16)7-5-11/h4-7,9-10,13-14,20H,8H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: The United Kingdom Paclobutrazol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol 04Nov2010 2010 doi:10.2903/j.efsa.2010.1876
+Paclobutrazol 76738-62-0 single chemical entity Component is identical to the substance Paclobutrazol 76738-62-0 1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pentan-3-ol Paclobutrazol C15H20ClN3O OC(C(C)(C)C)C(CC(C=C1)=CC=C1Cl)N2N=CN=C2 InChI=1S/C15H20ClN3O/c1-15(2,3)14(20)13(19-10-17-9-18-19)8-11-4-6-12(16)7-5-11/h4-7,9-10,13-14,20H,8H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: The United Kingdom Paclobutrazol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol 04Nov2010 2010 doi:10.2903/j.efsa.2010.1876
+Paclobutrazol 76738-62-0 single chemical entity Component is identical to the substance Paclobutrazol 76738-62-0 1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pentan-3-ol Paclobutrazol C15H20ClN3O OC(C(C)(C)C)C(CC(C=C1)=CC=C1Cl)N2N=CN=C2 InChI=1S/C15H20ClN3O/c1-15(2,3)14(20)13(19-10-17-9-18-19)8-11-4-6-12(16)7-5-11/h4-7,9-10,13-14,20H,8H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: The United Kingdom Paclobutrazol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol 04Nov2010 2010 doi:10.2903/j.efsa.2010.1876
+Paclobutrazol 76738-62-0 single chemical entity Component is identical to the substance Paclobutrazol 76738-62-0 1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pentan-3-ol Paclobutrazol C15H20ClN3O OC(C(C)(C)C)C(CC(C=C1)=CC=C1Cl)N2N=CN=C2 InChI=1S/C15H20ClN3O/c1-15(2,3)14(20)13(19-10-17-9-18-19)8-11-4-6-12(16)7-5-11/h4-7,9-10,13-14,20H,8H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: The United Kingdom Paclobutrazol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol 04Nov2010 2010 doi:10.2903/j.efsa.2010.1876
+Paclobutrazol 76738-62-0 single chemical entity Component is identical to the substance Paclobutrazol 76738-62-0 1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pentan-3-ol Paclobutrazol C15H20ClN3O OC(C(C)(C)C)C(CC(C=C1)=CC=C1Cl)N2N=CN=C2 InChI=1S/C15H20ClN3O/c1-15(2,3)14(20)13(19-10-17-9-18-19)8-11-4-6-12(16)7-5-11/h4-7,9-10,13-14,20H,8H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: The United Kingdom Paclobutrazol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol 04Nov2010 2010 doi:10.2903/j.efsa.2010.1876
+Paclobutrazol 76738-62-0 single chemical entity Component is identical to the substance Paclobutrazol 76738-62-0 1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pentan-3-ol Paclobutrazol C15H20ClN3O OC(C(C)(C)C)C(CC(C=C1)=CC=C1Cl)N2N=CN=C2 InChI=1S/C15H20ClN3O/c1-15(2,3)14(20)13(19-10-17-9-18-19)8-11-4-6-12(16)7-5-11/h4-7,9-10,13-14,20H,8H2,1-3H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: The United Kingdom Paclobutrazol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol 04Nov2010 2010 doi:10.2903/j.efsa.2010.1876
+Paclobutrazol 76738-62-0 single chemical entity Component is identical to the substance Paclobutrazol 76738-62-0 1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pentan-3-ol Paclobutrazol C15H20ClN3O OC(C(C)(C)C)C(CC(C=C1)=CC=C1Cl)N2N=CN=C2 InChI=1S/C15H20ClN3O/c1-15(2,3)14(20)13(19-10-17-9-18-19)8-11-4-6-12(16)7-5-11/h4-7,9-10,13-14,20H,8H2,1-3H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: The United Kingdom Paclobutrazol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol 04Nov2010 2010 doi:10.2903/j.efsa.2010.1876
+Paclobutrazol 76738-62-0 single chemical entity Component is identical to the substance Paclobutrazol 76738-62-0 1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pentan-3-ol Paclobutrazol C15H20ClN3O OC(C(C)(C)C)C(CC(C=C1)=CC=C1Cl)N2N=CN=C2 InChI=1S/C15H20ClN3O/c1-15(2,3)14(20)13(19-10-17-9-18-19)8-11-4-6-12(16)7-5-11/h4-7,9-10,13-14,20H,8H2,1-3H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Paclobutrazol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol 04Nov2010 2010 doi:10.2903/j.efsa.2010.1876
+Paclobutrazol 76738-62-0 single chemical entity Component is identical to the substance Paclobutrazol 76738-62-0 1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pentan-3-ol Paclobutrazol C15H20ClN3O OC(C(C)(C)C)C(CC(C=C1)=CC=C1Cl)N2N=CN=C2 InChI=1S/C15H20ClN3O/c1-15(2,3)14(20)13(19-10-17-9-18-19)8-11-4-6-12(16)7-5-11/h4-7,9-10,13-14,20H,8H2,1-3H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Paclobutrazol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol 04Nov2010 2010 doi:10.2903/j.efsa.2010.1876
+Paclobutrazol 76738-62-0 single chemical entity Component is identical to the substance Paclobutrazol 76738-62-0 1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pentan-3-ol Paclobutrazol C15H20ClN3O OC(C(C)(C)C)C(CC(C=C1)=CC=C1Cl)N2N=CN=C2 InChI=1S/C15H20ClN3O/c1-15(2,3)14(20)13(19-10-17-9-18-19)8-11-4-6-12(16)7-5-11/h4-7,9-10,13-14,20H,8H2,1-3H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Rat (as animal) Alderly Park Rat 16 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Paclobutrazol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol 04Nov2010 2010 doi:10.2903/j.efsa.2010.1876
+Paclobutrazol 76738-62-0 single chemical entity Component is identical to the substance Paclobutrazol 76738-62-0 1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pentan-3-ol Paclobutrazol C15H20ClN3O OC(C(C)(C)C)C(CC(C=C1)=CC=C1Cl)N2N=CN=C2 InChI=1S/C15H20ClN3O/c1-15(2,3)14(20)13(19-10-17-9-18-19)8-11-4-6-12(16)7-5-11/h4-7,9-10,13-14,20H,8H2,1-3H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Rat (as animal) Alderly Park Rat 16 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Paclobutrazol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol 04Nov2010 2010 doi:10.2903/j.efsa.2010.1876
+Paclobutrazol 76738-62-0 single chemical entity Component is identical to the substance Paclobutrazol 76738-62-0 1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pentan-3-ol Paclobutrazol C15H20ClN3O OC(C(C)(C)C)C(CC(C=C1)=CC=C1Cl)N2N=CN=C2 InChI=1S/C15H20ClN3O/c1-15(2,3)14(20)13(19-10-17-9-18-19)8-11-4-6-12(16)7-5-11/h4-7,9-10,13-14,20H,8H2,1-3H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Rat (as animal) Alderly Park Rat 16 Male/Female oral: gavage 12.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Paclobutrazol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol 04Nov2010 2010 doi:10.2903/j.efsa.2010.1876
+Paclobutrazol 76738-62-0 single chemical entity Component is identical to the substance Paclobutrazol 76738-62-0 1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pentan-3-ol Paclobutrazol C15H20ClN3O OC(C(C)(C)C)C(CC(C=C1)=CC=C1Cl)N2N=CN=C2 InChI=1S/C15H20ClN3O/c1-15(2,3)14(20)13(19-10-17-9-18-19)8-11-4-6-12(16)7-5-11/h4-7,9-10,13-14,20H,8H2,1-3H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Alderly Park Rat 6 Male oral: gavage 6.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Paclobutrazol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol 04Nov2010 2010 doi:10.2903/j.efsa.2010.1876
+Paclobutrazol 76738-62-0 single chemical entity Component is identical to the substance Paclobutrazol 76738-62-0 1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pentan-3-ol Paclobutrazol C15H20ClN3O OC(C(C)(C)C)C(CC(C=C1)=CC=C1Cl)N2N=CN=C2 InChI=1S/C15H20ClN3O/c1-15(2,3)14(20)13(19-10-17-9-18-19)8-11-4-6-12(16)7-5-11/h4-7,9-10,13-14,20H,8H2,1-3H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) C57BL 10 Male/Female intraperitoneal 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The United Kingdom Paclobutrazol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol 04Nov2010 2010 doi:10.2903/j.efsa.2010.1876
+Paclobutrazol 76738-62-0 single chemical entity Component is identical to the substance Paclobutrazol 76738-62-0 1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pentan-3-ol Paclobutrazol C15H20ClN3O OC(C(C)(C)C)C(CC(C=C1)=CC=C1Cl)N2N=CN=C2 InChI=1S/C15H20ClN3O/c1-15(2,3)14(20)13(19-10-17-9-18-19)8-11-4-6-12(16)7-5-11/h4-7,9-10,13-14,20H,8H2,1-3H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) C57BL 10 Male/Female intraperitoneal 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The United Kingdom Paclobutrazol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol 04Nov2010 2010 doi:10.2903/j.efsa.2010.1876
+Paclobutrazol 76738-62-0 single chemical entity Component is identical to the substance Paclobutrazol 76738-62-0 1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pentan-3-ol Paclobutrazol C15H20ClN3O OC(C(C)(C)C)C(CC(C=C1)=CC=C1Cl)N2N=CN=C2 InChI=1S/C15H20ClN3O/c1-15(2,3)14(20)13(19-10-17-9-18-19)8-11-4-6-12(16)7-5-11/h4-7,9-10,13-14,20H,8H2,1-3H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) C57BL 10 Male/Female intraperitoneal 72.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The United Kingdom Paclobutrazol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol 04Nov2010 2010 doi:10.2903/j.efsa.2010.1876
+Paclobutrazol 76738-62-0 single chemical entity Component is identical to the substance Paclobutrazol 76738-62-0 1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pentan-3-ol Paclobutrazol C15H20ClN3O OC(C(C)(C)C)C(CC(C=C1)=CC=C1Cl)N2N=CN=C2 InChI=1S/C15H20ClN3O/c1-15(2,3)14(20)13(19-10-17-9-18-19)8-11-4-6-12(16)7-5-11/h4-7,9-10,13-14,20H,8H2,1-3H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) C57BL 10 Male/Female oral: unspecified 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: The United Kingdom Paclobutrazol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol 04Nov2010 2010 doi:10.2903/j.efsa.2010.1876
+Paclobutrazol 76738-62-0 single chemical entity Component is identical to the substance Paclobutrazol 76738-62-0 1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pentan-3-ol Paclobutrazol C15H20ClN3O OC(C(C)(C)C)C(CC(C=C1)=CC=C1Cl)N2N=CN=C2 InChI=1S/C15H20ClN3O/c1-15(2,3)14(20)13(19-10-17-9-18-19)8-11-4-6-12(16)7-5-11/h4-7,9-10,13-14,20H,8H2,1-3H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) C57BL 10 Male/Female oral: unspecified 72.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: The United Kingdom Paclobutrazol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol 04Nov2010 2010 doi:10.2903/j.efsa.2010.1876
+Paclobutrazol 76738-62-0 single chemical entity Component is identical to the substance Paclobutrazol 76738-62-0 1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pentan-3-ol Paclobutrazol C15H20ClN3O OC(C(C)(C)C)C(CC(C=C1)=CC=C1Cl)N2N=CN=C2 InChI=1S/C15H20ClN3O/c1-15(2,3)14(20)13(19-10-17-9-18-19)8-11-4-6-12(16)7-5-11/h4-7,9-10,13-14,20H,8H2,1-3H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) C57BL 10 Male/Female oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: The United Kingdom Paclobutrazol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol 04Nov2010 2010 doi:10.2903/j.efsa.2010.1876
+Paclobutrazol 76738-62-0 single chemical entity Component is identical to the substance Paclobutrazol 76738-62-0 1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pentan-3-ol Paclobutrazol C15H20ClN3O OC(C(C)(C)C)C(CC(C=C1)=CC=C1Cl)N2N=CN=C2 InChI=1S/C15H20ClN3O/c1-15(2,3)14(20)13(19-10-17-9-18-19)8-11-4-6-12(16)7-5-11/h4-7,9-10,13-14,20H,8H2,1-3H3 organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Alderly Park Rat 5 Male oral: gavage 4.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Paclobutrazol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol 04Nov2010 2010 doi:10.2903/j.efsa.2010.1876
+Paclobutrazol 76738-62-0 single chemical entity Component is identical to the substance Paclobutrazol 76738-62-0 1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pentan-3-ol Paclobutrazol C15H20ClN3O OC(C(C)(C)C)C(CC(C=C1)=CC=C1Cl)N2N=CN=C2 InChI=1S/C15H20ClN3O/c1-15(2,3)14(20)13(19-10-17-9-18-19)8-11-4-6-12(16)7-5-11/h4-7,9-10,13-14,20H,8H2,1-3H3 organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Alderly Park Rat 5 Male oral: gavage 12.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Paclobutrazol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol 04Nov2010 2010 doi:10.2903/j.efsa.2010.1876
+Paclobutrazol 76738-62-0 single chemical entity Component is identical to the substance Paclobutrazol 76738-62-0 1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pentan-3-ol Paclobutrazol C15H20ClN3O OC(C(C)(C)C)C(CC(C=C1)=CC=C1Cl)N2N=CN=C2 InChI=1S/C15H20ClN3O/c1-15(2,3)14(20)13(19-10-17-9-18-19)8-11-4-6-12(16)7-5-11/h4-7,9-10,13-14,20H,8H2,1-3H3 organic compound Other Other chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) Yes Acceptable House mouse (as animal) CD-1 20 Male oral: gavage 5.0000000000 D yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Paclobutrazol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol 04Nov2010 2010 doi:10.2903/j.efsa.2010.1876
+Paclobutrazol 76738-62-0 single chemical entity Component is a metabolite of the substance Triazole lactic acid 2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole lactic acid C5H7N3O3 OC(Cn1cncn1)C(=O)O InChI=1S/C5H7N3O3/c9-4(5(10)11)1-8-3-6-2-7-8/h2-4,9H,1H2,(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative Rms: The United Kingdom Paclobutrazol (Additional Report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol 04Nov2010 2010 doi:10.2903/j.efsa.2010.1876
+Paclobutrazol 76738-62-0 single chemical entity Component is a metabolite of the substance Triazole lactic acid 2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole lactic acid C5H7N3O3 OC(Cn1cncn1)C(=O)O InChI=1S/C5H7N3O3/c9-4(5(10)11)1-8-3-6-2-7-8/h2-4,9H,1H2,(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative Rms: The United Kingdom Paclobutrazol (Additional Report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol 04Nov2010 2010 doi:10.2903/j.efsa.2010.1876
+Paclobutrazol 76738-62-0 single chemical entity Component is a metabolite of the substance Triazole lactic acid 2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole lactic acid C5H7N3O3 OC(Cn1cncn1)C(=O)O InChI=1S/C5H7N3O3/c9-4(5(10)11)1-8-3-6-2-7-8/h2-4,9H,1H2,(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative Rms: The United Kingdom Paclobutrazol (Additional Report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol 04Nov2010 2010 doi:10.2903/j.efsa.2010.1876
+Paclobutrazol 76738-62-0 single chemical entity Component is a metabolite of the substance Triazole lactic acid 2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole lactic acid C5H7N3O3 OC(Cn1cncn1)C(=O)O InChI=1S/C5H7N3O3/c9-4(5(10)11)1-8-3-6-2-7-8/h2-4,9H,1H2,(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative Rms: The United Kingdom Paclobutrazol (Additional Report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol 04Nov2010 2010 doi:10.2903/j.efsa.2010.1876
+Paclobutrazol 76738-62-0 single chemical entity Component is a metabolite of the substance Triazole lactic acid 2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole lactic acid C5H7N3O3 OC(Cn1cncn1)C(=O)O InChI=1S/C5H7N3O3/c9-4(5(10)11)1-8-3-6-2-7-8/h2-4,9H,1H2,(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle with Negative Rms: The United Kingdom Paclobutrazol (Additional Report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol 04Nov2010 2010 doi:10.2903/j.efsa.2010.1876
+Paclobutrazol 76738-62-0 single chemical entity Component is a metabolite of the substance Triazole lactic acid 2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole lactic acid C5H7N3O3 OC(Cn1cncn1)C(=O)O InChI=1S/C5H7N3O3/c9-4(5(10)11)1-8-3-6-2-7-8/h2-4,9H,1H2,(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle without Negative Rms: The United Kingdom Paclobutrazol (Additional Report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol 04Nov2010 2010 doi:10.2903/j.efsa.2010.1876
+Paclobutrazol 76738-62-0 single chemical entity Component is a metabolite of the substance Triazole lactic acid 2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole lactic acid C5H7N3O3 OC(Cn1cncn1)C(=O)O InChI=1S/C5H7N3O3/c9-4(5(10)11)1-8-3-6-2-7-8/h2-4,9H,1H2,(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative Rms: The United Kingdom Paclobutrazol (Additional Report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol 04Nov2010 2010 doi:10.2903/j.efsa.2010.1876
+Paclobutrazol 76738-62-0 single chemical entity Component is a metabolite of the substance Triazole lactic acid 2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole lactic acid C5H7N3O3 OC(Cn1cncn1)C(=O)O InChI=1S/C5H7N3O3/c9-4(5(10)11)1-8-3-6-2-7-8/h2-4,9H,1H2,(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative Rms: The United Kingdom Paclobutrazol (Additional Report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol 04Nov2010 2010 doi:10.2903/j.efsa.2010.1876
+Paclobutrazol 76738-62-0 single chemical entity Component is a metabolite of the substance Triazole lactic acid 2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole lactic acid C5H7N3O3 OC(Cn1cncn1)C(=O)O InChI=1S/C5H7N3O3/c9-4(5(10)11)1-8-3-6-2-7-8/h2-4,9H,1H2,(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative Rms: The United Kingdom Paclobutrazol (Additional Report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol 04Nov2010 2010 doi:10.2903/j.efsa.2010.1876
+Paclobutrazol 76738-62-0 single chemical entity Component is a metabolite of the substance Triazole lactic acid 2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole lactic acid C5H7N3O3 OC(Cn1cncn1)C(=O)O InChI=1S/C5H7N3O3/c9-4(5(10)11)1-8-3-6-2-7-8/h2-4,9H,1H2,(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative Rms: The United Kingdom Paclobutrazol (Additional Report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol 04Nov2010 2010 doi:10.2903/j.efsa.2010.1876
+Paclobutrazol 76738-62-0 single chemical entity Component is a metabolite of the substance Triazole lactic acid 2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole lactic acid C5H7N3O3 OC(Cn1cncn1)C(=O)O InChI=1S/C5H7N3O3/c9-4(5(10)11)1-8-3-6-2-7-8/h2-4,9H,1H2,(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative Rms: The United Kingdom Paclobutrazol (Additional Report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol 04Nov2010 2010 doi:10.2903/j.efsa.2010.1876
+Paclobutrazol 76738-62-0 single chemical entity Component is a metabolite of the substance Triazole lactic acid 2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole lactic acid C5H7N3O3 OC(Cn1cncn1)C(=O)O InChI=1S/C5H7N3O3/c9-4(5(10)11)1-8-3-6-2-7-8/h2-4,9H,1H2,(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative Rms: The United Kingdom Paclobutrazol (Additional Report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol 04Nov2010 2010 doi:10.2903/j.efsa.2010.1876
+Paclobutrazol 76738-62-0 single chemical entity Component is a metabolite of the substance Triazole lactic acid 2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole lactic acid C5H7N3O3 OC(Cn1cncn1)C(=O)O InChI=1S/C5H7N3O3/c9-4(5(10)11)1-8-3-6-2-7-8/h2-4,9H,1H2,(H,10,11) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported no data with Negative Rms: The United Kingdom Paclobutrazol (Additional Report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol 04Nov2010 2010 doi:10.2903/j.efsa.2010.1876
+Paclobutrazol 76738-62-0 single chemical entity Component is a metabolite of the substance Triazole lactic acid 2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole lactic acid C5H7N3O3 OC(Cn1cncn1)C(=O)O InChI=1S/C5H7N3O3/c9-4(5(10)11)1-8-3-6-2-7-8/h2-4,9H,1H2,(H,10,11) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported no data without Negative Rms: The United Kingdom Paclobutrazol (Additional Report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol 04Nov2010 2010 doi:10.2903/j.efsa.2010.1876
+Paclobutrazol 76738-62-0 single chemical entity Component is a metabolite of the substance Triazole lactic acid 2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole lactic acid C5H7N3O3 OC(Cn1cncn1)C(=O)O InChI=1S/C5H7N3O3/c9-4(5(10)11)1-8-3-6-2-7-8/h2-4,9H,1H2,(H,10,11) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Rat (as animal) lymphocytes Not reported no data with Negative Rms: The United Kingdom Paclobutrazol (Additional Report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol 04Nov2010 2010 doi:10.2903/j.efsa.2010.1876
+Paclobutrazol 76738-62-0 single chemical entity Component is a metabolite of the substance Triazole lactic acid 2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole lactic acid C5H7N3O3 OC(Cn1cncn1)C(=O)O InChI=1S/C5H7N3O3/c9-4(5(10)11)1-8-3-6-2-7-8/h2-4,9H,1H2,(H,10,11) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Rat (as animal) lymphocytes Not reported no data without Negative Rms: The United Kingdom Paclobutrazol (Additional Report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol 04Nov2010 2010 doi:10.2903/j.efsa.2010.1876
+Orthosulfamuron 213464-77-8 single chemical entity Component is identical to the substance Orthosulfamuron 213464-77-8 1-(4,6-dimethoxypyrimidin-2-yl)-3-[2-(dimethylcarbamoyl)phenylsulfamoyl]urea Orthosulfamuron C16H20N6O6S CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C16H20N6O6S/c1-22(2)14(23)10-7-5-6-8-11(10)20-29(25,26)21-16(24)19-15-17-12(27-3)9-13(18-15)28-4/h5-9,20H,1-4H3,(H2,17,18,19,21,24) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Italy Orthosulfamuron 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is identical to the substance Orthosulfamuron 213464-77-8 1-(4,6-dimethoxypyrimidin-2-yl)-3-[2-(dimethylcarbamoyl)phenylsulfamoyl]urea Orthosulfamuron C16H20N6O6S CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C16H20N6O6S/c1-22(2)14(23)10-7-5-6-8-11(10)20-29(25,26)21-16(24)19-15-17-12(27-3)9-13(18-15)28-4/h5-9,20H,1-4H3,(H2,17,18,19,21,24) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Italy Orthosulfamuron 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is identical to the substance Orthosulfamuron 213464-77-8 1-(4,6-dimethoxypyrimidin-2-yl)-3-[2-(dimethylcarbamoyl)phenylsulfamoyl]urea Orthosulfamuron C16H20N6O6S CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C16H20N6O6S/c1-22(2)14(23)10-7-5-6-8-11(10)20-29(25,26)21-16(24)19-15-17-12(27-3)9-13(18-15)28-4/h5-9,20H,1-4H3,(H2,17,18,19,21,24) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Italy Orthosulfamuron 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is identical to the substance Orthosulfamuron 213464-77-8 1-(4,6-dimethoxypyrimidin-2-yl)-3-[2-(dimethylcarbamoyl)phenylsulfamoyl]urea Orthosulfamuron C16H20N6O6S CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C16H20N6O6S/c1-22(2)14(23)10-7-5-6-8-11(10)20-29(25,26)21-16(24)19-15-17-12(27-3)9-13(18-15)28-4/h5-9,20H,1-4H3,(H2,17,18,19,21,24) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Italy Orthosulfamuron 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is identical to the substance Orthosulfamuron 213464-77-8 1-(4,6-dimethoxypyrimidin-2-yl)-3-[2-(dimethylcarbamoyl)phenylsulfamoyl]urea Orthosulfamuron C16H20N6O6S CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C16H20N6O6S/c1-22(2)14(23)10-7-5-6-8-11(10)20-29(25,26)21-16(24)19-15-17-12(27-3)9-13(18-15)28-4/h5-9,20H,1-4H3,(H2,17,18,19,21,24) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Italy Orthosulfamuron 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is identical to the substance Orthosulfamuron 213464-77-8 1-(4,6-dimethoxypyrimidin-2-yl)-3-[2-(dimethylcarbamoyl)phenylsulfamoyl]urea Orthosulfamuron C16H20N6O6S CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C16H20N6O6S/c1-22(2)14(23)10-7-5-6-8-11(10)20-29(25,26)21-16(24)19-15-17-12(27-3)9-13(18-15)28-4/h5-9,20H,1-4H3,(H2,17,18,19,21,24) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Italy Orthosulfamuron 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is identical to the substance Orthosulfamuron 213464-77-8 1-(4,6-dimethoxypyrimidin-2-yl)-3-[2-(dimethylcarbamoyl)phenylsulfamoyl]urea Orthosulfamuron C16H20N6O6S CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C16H20N6O6S/c1-22(2)14(23)10-7-5-6-8-11(10)20-29(25,26)21-16(24)19-15-17-12(27-3)9-13(18-15)28-4/h5-9,20H,1-4H3,(H2,17,18,19,21,24) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Italy Orthosulfamuron 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is identical to the substance Orthosulfamuron 213464-77-8 1-(4,6-dimethoxypyrimidin-2-yl)-3-[2-(dimethylcarbamoyl)phenylsulfamoyl]urea Orthosulfamuron C16H20N6O6S CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C16H20N6O6S/c1-22(2)14(23)10-7-5-6-8-11(10)20-29(25,26)21-16(24)19-15-17-12(27-3)9-13(18-15)28-4/h5-9,20H,1-4H3,(H2,17,18,19,21,24) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Italy Orthosulfamuron 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is identical to the substance Orthosulfamuron 213464-77-8 1-(4,6-dimethoxypyrimidin-2-yl)-3-[2-(dimethylcarbamoyl)phenylsulfamoyl]urea Orthosulfamuron C16H20N6O6S CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C16H20N6O6S/c1-22(2)14(23)10-7-5-6-8-11(10)20-29(25,26)21-16(24)19-15-17-12(27-3)9-13(18-15)28-4/h5-9,20H,1-4H3,(H2,17,18,19,21,24) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Italy Orthosulfamuron 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is identical to the substance Orthosulfamuron 213464-77-8 1-(4,6-dimethoxypyrimidin-2-yl)-3-[2-(dimethylcarbamoyl)phenylsulfamoyl]urea Orthosulfamuron C16H20N6O6S CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C16H20N6O6S/c1-22(2)14(23)10-7-5-6-8-11(10)20-29(25,26)21-16(24)19-15-17-12(27-3)9-13(18-15)28-4/h5-9,20H,1-4H3,(H2,17,18,19,21,24) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Italy Orthosulfamuron 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is identical to the substance Orthosulfamuron 213464-77-8 1-(4,6-dimethoxypyrimidin-2-yl)-3-[2-(dimethylcarbamoyl)phenylsulfamoyl]urea Orthosulfamuron C16H20N6O6S CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C16H20N6O6S/c1-22(2)14(23)10-7-5-6-8-11(10)20-29(25,26)21-16(24)19-15-17-12(27-3)9-13(18-15)28-4/h5-9,20H,1-4H3,(H2,17,18,19,21,24) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Italy Orthosulfamuron 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is identical to the substance Orthosulfamuron 213464-77-8 1-(4,6-dimethoxypyrimidin-2-yl)-3-[2-(dimethylcarbamoyl)phenylsulfamoyl]urea Orthosulfamuron C16H20N6O6S CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C16H20N6O6S/c1-22(2)14(23)10-7-5-6-8-11(10)20-29(25,26)21-16(24)19-15-17-12(27-3)9-13(18-15)28-4/h5-9,20H,1-4H3,(H2,17,18,19,21,24) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Italy Orthosulfamuron 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is identical to the substance Orthosulfamuron 213464-77-8 1-(4,6-dimethoxypyrimidin-2-yl)-3-[2-(dimethylcarbamoyl)phenylsulfamoyl]urea Orthosulfamuron C16H20N6O6S CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C16H20N6O6S/c1-22(2)14(23)10-7-5-6-8-11(10)20-29(25,26)21-16(24)19-15-17-12(27-3)9-13(18-15)28-4/h5-9,20H,1-4H3,(H2,17,18,19,21,24) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Italy Orthosulfamuron 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is identical to the substance Orthosulfamuron 213464-77-8 1-(4,6-dimethoxypyrimidin-2-yl)-3-[2-(dimethylcarbamoyl)phenylsulfamoyl]urea Orthosulfamuron C16H20N6O6S CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C16H20N6O6S/c1-22(2)14(23)10-7-5-6-8-11(10)20-29(25,26)21-16(24)19-15-17-12(27-3)9-13(18-15)28-4/h5-9,20H,1-4H3,(H2,17,18,19,21,24) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Italy Orthosulfamuron 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is identical to the substance Orthosulfamuron 213464-77-8 1-(4,6-dimethoxypyrimidin-2-yl)-3-[2-(dimethylcarbamoyl)phenylsulfamoyl]urea Orthosulfamuron C16H20N6O6S CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C16H20N6O6S/c1-22(2)14(23)10-7-5-6-8-11(10)20-29(25,26)21-16(24)19-15-17-12(27-3)9-13(18-15)28-4/h5-9,20H,1-4H3,(H2,17,18,19,21,24) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 24 Male/Female oral: unspecified 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Italy Orthosulfamuron 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is identical to the substance Orthosulfamuron 213464-77-8 1-(4,6-dimethoxypyrimidin-2-yl)-3-[2-(dimethylcarbamoyl)phenylsulfamoyl]urea Orthosulfamuron C16H20N6O6S CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C16H20N6O6S/c1-22(2)14(23)10-7-5-6-8-11(10)20-29(25,26)21-16(24)19-15-17-12(27-3)9-13(18-15)28-4/h5-9,20H,1-4H3,(H2,17,18,19,21,24) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 24 Male/Female oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Italy Orthosulfamuron 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is identical to the substance Orthosulfamuron 213464-77-8 1-(4,6-dimethoxypyrimidin-2-yl)-3-[2-(dimethylcarbamoyl)phenylsulfamoyl]urea Orthosulfamuron C16H20N6O6S CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C16H20N6O6S/c1-22(2)14(23)10-7-5-6-8-11(10)20-29(25,26)21-16(24)19-15-17-12(27-3)9-13(18-15)28-4/h5-9,20H,1-4H3,(H2,17,18,19,21,24) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration mammalian germ cell cytogenetic assay in vivo According to OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test) No Acceptable House mouse (as animal) NMRI 12 Male oral: unspecified 48.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Italy Orthosulfamuron 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is identical to the substance Orthosulfamuron 213464-77-8 1-(4,6-dimethoxypyrimidin-2-yl)-3-[2-(dimethylcarbamoyl)phenylsulfamoyl]urea Orthosulfamuron C16H20N6O6S CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C16H20N6O6S/c1-22(2)14(23)10-7-5-6-8-11(10)20-29(25,26)21-16(24)19-15-17-12(27-3)9-13(18-15)28-4/h5-9,20H,1-4H3,(H2,17,18,19,21,24) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration mammalian germ cell cytogenetic assay in vivo According to OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test) No Acceptable House mouse (as animal) NMRI 12 Male oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Italy Orthosulfamuron 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is a metabolite of the substance [2-(dimethylcarbamoyl)phenyl] sulfamic acid [2-(dimethylcarbamoyl)phenyl]sulfamic acid Not in list C9H12N2O4S CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)O InChI=1S/C9H12N2O4S/c1-11(2)9(12)7-5-3-4-6-8(7)10-16(13,14)15/h3-6,10H,1-2H3,(H,13,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Italy Orthosulfamuron 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is a metabolite of the substance [2-(dimethylcarbamoyl)phenyl] sulfamic acid [2-(dimethylcarbamoyl)phenyl]sulfamic acid Not in list C9H12N2O4S CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)O InChI=1S/C9H12N2O4S/c1-11(2)9(12)7-5-3-4-6-8(7)10-16(13,14)15/h3-6,10H,1-2H3,(H,13,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Italy Orthosulfamuron 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is a metabolite of the substance [2-(dimethylcarbamoyl)phenyl] sulfamic acid [2-(dimethylcarbamoyl)phenyl]sulfamic acid Not in list C9H12N2O4S CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)O InChI=1S/C9H12N2O4S/c1-11(2)9(12)7-5-3-4-6-8(7)10-16(13,14)15/h3-6,10H,1-2H3,(H,13,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Italy Orthosulfamuron 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is a metabolite of the substance [2-(dimethylcarbamoyl)phenyl] sulfamic acid [2-(dimethylcarbamoyl)phenyl]sulfamic acid Not in list C9H12N2O4S CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)O InChI=1S/C9H12N2O4S/c1-11(2)9(12)7-5-3-4-6-8(7)10-16(13,14)15/h3-6,10H,1-2H3,(H,13,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Italy Orthosulfamuron 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is a metabolite of the substance [2-(dimethylcarbamoyl)phenyl] sulfamic acid [2-(dimethylcarbamoyl)phenyl]sulfamic acid Not in list C9H12N2O4S CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)O InChI=1S/C9H12N2O4S/c1-11(2)9(12)7-5-3-4-6-8(7)10-16(13,14)15/h3-6,10H,1-2H3,(H,13,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Italy Orthosulfamuron 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is a metabolite of the substance [2-(dimethylcarbamoyl)phenyl] sulfamic acid [2-(dimethylcarbamoyl)phenyl]sulfamic acid Not in list C9H12N2O4S CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)O InChI=1S/C9H12N2O4S/c1-11(2)9(12)7-5-3-4-6-8(7)10-16(13,14)15/h3-6,10H,1-2H3,(H,13,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Italy Orthosulfamuron 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is a metabolite of the substance [2-(dimethylcarbamoyl)phenyl] sulfamic acid [2-(dimethylcarbamoyl)phenyl]sulfamic acid Not in list C9H12N2O4S CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)O InChI=1S/C9H12N2O4S/c1-11(2)9(12)7-5-3-4-6-8(7)10-16(13,14)15/h3-6,10H,1-2H3,(H,13,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Italy Orthosulfamuron 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is a metabolite of the substance [2-(dimethylcarbamoyl)phenyl] sulfamic acid [2-(dimethylcarbamoyl)phenyl]sulfamic acid Not in list C9H12N2O4S CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)O InChI=1S/C9H12N2O4S/c1-11(2)9(12)7-5-3-4-6-8(7)10-16(13,14)15/h3-6,10H,1-2H3,(H,13,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Italy Orthosulfamuron 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is a metabolite of the substance [2-(dimethylcarbamoyl)phenyl] sulfamic acid [2-(dimethylcarbamoyl)phenyl]sulfamic acid Not in list C9H12N2O4S CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)O InChI=1S/C9H12N2O4S/c1-11(2)9(12)7-5-3-4-6-8(7)10-16(13,14)15/h3-6,10H,1-2H3,(H,13,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Italy Orthosulfamuron 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is a metabolite of the substance [2-(dimethylcarbamoyl)phenyl] sulfamic acid [2-(dimethylcarbamoyl)phenyl]sulfamic acid Not in list C9H12N2O4S CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)O InChI=1S/C9H12N2O4S/c1-11(2)9(12)7-5-3-4-6-8(7)10-16(13,14)15/h3-6,10H,1-2H3,(H,13,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Italy Orthosulfamuron 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is a metabolite of the substance [2-(dimethylcarbamoyl)phenyl] sulfamic acid [2-(dimethylcarbamoyl)phenyl]sulfamic acid Not in list C9H12N2O4S CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)O InChI=1S/C9H12N2O4S/c1-11(2)9(12)7-5-3-4-6-8(7)10-16(13,14)15/h3-6,10H,1-2H3,(H,13,14,15) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Italy Orthosulfamuron 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is a metabolite of the substance [2-(dimethylcarbamoyl)phenyl] sulfamic acid [2-(dimethylcarbamoyl)phenyl]sulfamic acid Not in list C9H12N2O4S CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)O InChI=1S/C9H12N2O4S/c1-11(2)9(12)7-5-3-4-6-8(7)10-16(13,14)15/h3-6,10H,1-2H3,(H,13,14,15) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Italy Orthosulfamuron 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is a metabolite of the substance [2-(dimethylcarbamoyl)phenyl] sulfamic acid [2-(dimethylcarbamoyl)phenyl]sulfamic acid Not in list C9H12N2O4S CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)O InChI=1S/C9H12N2O4S/c1-11(2)9(12)7-5-3-4-6-8(7)10-16(13,14)15/h3-6,10H,1-2H3,(H,13,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Italy Orthosulfamuron 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is a metabolite of the substance [2-(dimethylcarbamoyl)phenyl] sulfamic acid [2-(dimethylcarbamoyl)phenyl]sulfamic acid Not in list C9H12N2O4S CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)O InChI=1S/C9H12N2O4S/c1-11(2)9(12)7-5-3-4-6-8(7)10-16(13,14)15/h3-6,10H,1-2H3,(H,13,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Italy Orthosulfamuron 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is a metabolite of the substance (4,6-dimethoxypyrimidin-2-yl)urea 1-(4,6-dimethoxypyrimidin-2-yl)urea Not in list C7H10N4O3 O=C(N)Nc1nc(cc(OC)n1)OC InChI=1S/C7H10N4O3/c1-13-4-3-5(14-2)10-7(9-4)11-6(8)12/h3H,1-2H3,(H3,8,9,10,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Italy Orthosulfamuron 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is a metabolite of the substance (4,6-dimethoxypyrimidin-2-yl)urea 1-(4,6-dimethoxypyrimidin-2-yl)urea Not in list C7H10N4O3 O=C(N)Nc1nc(cc(OC)n1)OC InChI=1S/C7H10N4O3/c1-13-4-3-5(14-2)10-7(9-4)11-6(8)12/h3H,1-2H3,(H3,8,9,10,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Italy Orthosulfamuron 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is a metabolite of the substance (4,6-dimethoxypyrimidin-2-yl)urea 1-(4,6-dimethoxypyrimidin-2-yl)urea Not in list C7H10N4O3 O=C(N)Nc1nc(cc(OC)n1)OC InChI=1S/C7H10N4O3/c1-13-4-3-5(14-2)10-7(9-4)11-6(8)12/h3H,1-2H3,(H3,8,9,10,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Italy Orthosulfamuron 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is a metabolite of the substance (4,6-dimethoxypyrimidin-2-yl)urea 1-(4,6-dimethoxypyrimidin-2-yl)urea Not in list C7H10N4O3 O=C(N)Nc1nc(cc(OC)n1)OC InChI=1S/C7H10N4O3/c1-13-4-3-5(14-2)10-7(9-4)11-6(8)12/h3H,1-2H3,(H3,8,9,10,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Italy Orthosulfamuron 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is a metabolite of the substance (4,6-dimethoxypyrimidin-2-yl)urea 1-(4,6-dimethoxypyrimidin-2-yl)urea Not in list C7H10N4O3 O=C(N)Nc1nc(cc(OC)n1)OC InChI=1S/C7H10N4O3/c1-13-4-3-5(14-2)10-7(9-4)11-6(8)12/h3H,1-2H3,(H3,8,9,10,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Italy Orthosulfamuron 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is a metabolite of the substance (4,6-dimethoxypyrimidin-2-yl)urea 1-(4,6-dimethoxypyrimidin-2-yl)urea Not in list C7H10N4O3 O=C(N)Nc1nc(cc(OC)n1)OC InChI=1S/C7H10N4O3/c1-13-4-3-5(14-2)10-7(9-4)11-6(8)12/h3H,1-2H3,(H3,8,9,10,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Italy Orthosulfamuron 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is a metabolite of the substance (4,6-dimethoxypyrimidin-2-yl)urea 1-(4,6-dimethoxypyrimidin-2-yl)urea Not in list C7H10N4O3 O=C(N)Nc1nc(cc(OC)n1)OC InChI=1S/C7H10N4O3/c1-13-4-3-5(14-2)10-7(9-4)11-6(8)12/h3H,1-2H3,(H3,8,9,10,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Italy Orthosulfamuron 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is a metabolite of the substance (4,6-dimethoxypyrimidin-2-yl)urea 1-(4,6-dimethoxypyrimidin-2-yl)urea Not in list C7H10N4O3 O=C(N)Nc1nc(cc(OC)n1)OC InChI=1S/C7H10N4O3/c1-13-4-3-5(14-2)10-7(9-4)11-6(8)12/h3H,1-2H3,(H3,8,9,10,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Italy Orthosulfamuron 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is a metabolite of the substance (4,6-dimethoxypyrimidin-2-yl)urea 1-(4,6-dimethoxypyrimidin-2-yl)urea Not in list C7H10N4O3 O=C(N)Nc1nc(cc(OC)n1)OC InChI=1S/C7H10N4O3/c1-13-4-3-5(14-2)10-7(9-4)11-6(8)12/h3H,1-2H3,(H3,8,9,10,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Italy Orthosulfamuron 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is a metabolite of the substance (4,6-dimethoxypyrimidin-2-yl)urea 1-(4,6-dimethoxypyrimidin-2-yl)urea Not in list C7H10N4O3 O=C(N)Nc1nc(cc(OC)n1)OC InChI=1S/C7H10N4O3/c1-13-4-3-5(14-2)10-7(9-4)11-6(8)12/h3H,1-2H3,(H3,8,9,10,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Italy Orthosulfamuron 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is a metabolite of the substance (4,6-dimethoxypyrimidin-2-yl)urea 1-(4,6-dimethoxypyrimidin-2-yl)urea Not in list C7H10N4O3 O=C(N)Nc1nc(cc(OC)n1)OC InChI=1S/C7H10N4O3/c1-13-4-3-5(14-2)10-7(9-4)11-6(8)12/h3H,1-2H3,(H3,8,9,10,11,12) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Italy Orthosulfamuron 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is a metabolite of the substance (4,6-dimethoxypyrimidin-2-yl)urea 1-(4,6-dimethoxypyrimidin-2-yl)urea Not in list C7H10N4O3 O=C(N)Nc1nc(cc(OC)n1)OC InChI=1S/C7H10N4O3/c1-13-4-3-5(14-2)10-7(9-4)11-6(8)12/h3H,1-2H3,(H3,8,9,10,11,12) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Italy Orthosulfamuron 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is a metabolite of the substance (4,6-dimethoxypyrimidin-2-yl)urea 1-(4,6-dimethoxypyrimidin-2-yl)urea Not in list C7H10N4O3 O=C(N)Nc1nc(cc(OC)n1)OC InChI=1S/C7H10N4O3/c1-13-4-3-5(14-2)10-7(9-4)11-6(8)12/h3H,1-2H3,(H3,8,9,10,11,12) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Italy Orthosulfamuron 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is a metabolite of the substance (4,6-dimethoxypyrimidin-2-yl)urea 1-(4,6-dimethoxypyrimidin-2-yl)urea Not in list C7H10N4O3 O=C(N)Nc1nc(cc(OC)n1)OC InChI=1S/C7H10N4O3/c1-13-4-3-5(14-2)10-7(9-4)11-6(8)12/h3H,1-2H3,(H3,8,9,10,11,12) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Italy Orthosulfamuron 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is a metabolite of the substance 1-(4-methoxy-6-hydroxypyrimidin-2-yl)-3-[2-(2-dimethylcarbamoyl)phenylsulfamoyl]urea 2-{[({[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]amino}oxy)sulfinyl]amino}-N,N-dimethylbenzamide Not in list C15H18N6O6S O=C(Nc1nc(O)cc(OC)n1)NOS(=O)Nc2ccccc2C(=O)N(C)C InChI=1S/C15H18N6O6S/c1-21(2)13(23)9-6-4-5-7-10(9)20-28(25)27-19-15(24)18-14-16-11(22)8-12(17-14)26-3/h4-8,20H,1-3H3,(H3,16,17,18,19,22,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Italy Orthosulfamuron 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is a metabolite of the substance 1-(4-methoxy-6-hydroxypyrimidin-2-yl)-3-[2-(2-dimethylcarbamoyl)phenylsulfamoyl]urea 2-{[({[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]amino}oxy)sulfinyl]amino}-N,N-dimethylbenzamide Not in list C15H18N6O6S O=C(Nc1nc(O)cc(OC)n1)NOS(=O)Nc2ccccc2C(=O)N(C)C InChI=1S/C15H18N6O6S/c1-21(2)13(23)9-6-4-5-7-10(9)20-28(25)27-19-15(24)18-14-16-11(22)8-12(17-14)26-3/h4-8,20H,1-3H3,(H3,16,17,18,19,22,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Italy Orthosulfamuron 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is a metabolite of the substance 1-(4-methoxy-6-hydroxypyrimidin-2-yl)-3-[2-(2-dimethylcarbamoyl)phenylsulfamoyl]urea 2-{[({[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]amino}oxy)sulfinyl]amino}-N,N-dimethylbenzamide Not in list C15H18N6O6S O=C(Nc1nc(O)cc(OC)n1)NOS(=O)Nc2ccccc2C(=O)N(C)C InChI=1S/C15H18N6O6S/c1-21(2)13(23)9-6-4-5-7-10(9)20-28(25)27-19-15(24)18-14-16-11(22)8-12(17-14)26-3/h4-8,20H,1-3H3,(H3,16,17,18,19,22,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Italy Orthosulfamuron 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is a metabolite of the substance 1-(4-methoxy-6-hydroxypyrimidin-2-yl)-3-[2-(2-dimethylcarbamoyl)phenylsulfamoyl]urea 2-{[({[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]amino}oxy)sulfinyl]amino}-N,N-dimethylbenzamide Not in list C15H18N6O6S O=C(Nc1nc(O)cc(OC)n1)NOS(=O)Nc2ccccc2C(=O)N(C)C InChI=1S/C15H18N6O6S/c1-21(2)13(23)9-6-4-5-7-10(9)20-28(25)27-19-15(24)18-14-16-11(22)8-12(17-14)26-3/h4-8,20H,1-3H3,(H3,16,17,18,19,22,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Italy Orthosulfamuron 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is a metabolite of the substance 1-(4-methoxy-6-hydroxypyrimidin-2-yl)-3-[2-(2-dimethylcarbamoyl)phenylsulfamoyl]urea 2-{[({[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]amino}oxy)sulfinyl]amino}-N,N-dimethylbenzamide Not in list C15H18N6O6S O=C(Nc1nc(O)cc(OC)n1)NOS(=O)Nc2ccccc2C(=O)N(C)C InChI=1S/C15H18N6O6S/c1-21(2)13(23)9-6-4-5-7-10(9)20-28(25)27-19-15(24)18-14-16-11(22)8-12(17-14)26-3/h4-8,20H,1-3H3,(H3,16,17,18,19,22,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Italy Orthosulfamuron 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is a metabolite of the substance 1-(4-methoxy-6-hydroxypyrimidin-2-yl)-3-[2-(2-dimethylcarbamoyl)phenylsulfamoyl]urea 2-{[({[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]amino}oxy)sulfinyl]amino}-N,N-dimethylbenzamide Not in list C15H18N6O6S O=C(Nc1nc(O)cc(OC)n1)NOS(=O)Nc2ccccc2C(=O)N(C)C InChI=1S/C15H18N6O6S/c1-21(2)13(23)9-6-4-5-7-10(9)20-28(25)27-19-15(24)18-14-16-11(22)8-12(17-14)26-3/h4-8,20H,1-3H3,(H3,16,17,18,19,22,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Italy Orthosulfamuron 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is a metabolite of the substance 1-(4-methoxy-6-hydroxypyrimidin-2-yl)-3-[2-(2-dimethylcarbamoyl)phenylsulfamoyl]urea 2-{[({[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]amino}oxy)sulfinyl]amino}-N,N-dimethylbenzamide Not in list C15H18N6O6S O=C(Nc1nc(O)cc(OC)n1)NOS(=O)Nc2ccccc2C(=O)N(C)C InChI=1S/C15H18N6O6S/c1-21(2)13(23)9-6-4-5-7-10(9)20-28(25)27-19-15(24)18-14-16-11(22)8-12(17-14)26-3/h4-8,20H,1-3H3,(H3,16,17,18,19,22,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Italy Orthosulfamuron 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is a metabolite of the substance 1-(4-methoxy-6-hydroxypyrimidin-2-yl)-3-[2-(2-dimethylcarbamoyl)phenylsulfamoyl]urea 2-{[({[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]amino}oxy)sulfinyl]amino}-N,N-dimethylbenzamide Not in list C15H18N6O6S O=C(Nc1nc(O)cc(OC)n1)NOS(=O)Nc2ccccc2C(=O)N(C)C InChI=1S/C15H18N6O6S/c1-21(2)13(23)9-6-4-5-7-10(9)20-28(25)27-19-15(24)18-14-16-11(22)8-12(17-14)26-3/h4-8,20H,1-3H3,(H3,16,17,18,19,22,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Italy Orthosulfamuron 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is a metabolite of the substance 1-(4-methoxy-6-hydroxypyrimidin-2-yl)-3-[2-(2-dimethylcarbamoyl)phenylsulfamoyl]urea 2-{[({[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]amino}oxy)sulfinyl]amino}-N,N-dimethylbenzamide Not in list C15H18N6O6S O=C(Nc1nc(O)cc(OC)n1)NOS(=O)Nc2ccccc2C(=O)N(C)C InChI=1S/C15H18N6O6S/c1-21(2)13(23)9-6-4-5-7-10(9)20-28(25)27-19-15(24)18-14-16-11(22)8-12(17-14)26-3/h4-8,20H,1-3H3,(H3,16,17,18,19,22,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Italy Orthosulfamuron 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is a metabolite of the substance 1-(4-methoxy-6-hydroxypyrimidin-2-yl)-3-[2-(2-dimethylcarbamoyl)phenylsulfamoyl]urea 2-{[({[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]amino}oxy)sulfinyl]amino}-N,N-dimethylbenzamide Not in list C15H18N6O6S O=C(Nc1nc(O)cc(OC)n1)NOS(=O)Nc2ccccc2C(=O)N(C)C InChI=1S/C15H18N6O6S/c1-21(2)13(23)9-6-4-5-7-10(9)20-28(25)27-19-15(24)18-14-16-11(22)8-12(17-14)26-3/h4-8,20H,1-3H3,(H3,16,17,18,19,22,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Italy Orthosulfamuron 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is a metabolite of the substance 1-(4-methoxy-6-hydroxypyrimidin-2-yl)-3-[2-(2-dimethylcarbamoyl)phenylsulfamoyl]urea 2-{[({[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]amino}oxy)sulfinyl]amino}-N,N-dimethylbenzamide Not in list C15H18N6O6S O=C(Nc1nc(O)cc(OC)n1)NOS(=O)Nc2ccccc2C(=O)N(C)C InChI=1S/C15H18N6O6S/c1-21(2)13(23)9-6-4-5-7-10(9)20-28(25)27-19-15(24)18-14-16-11(22)8-12(17-14)26-3/h4-8,20H,1-3H3,(H3,16,17,18,19,22,24) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Italy Orthosulfamuron 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is a metabolite of the substance 1-(4-methoxy-6-hydroxypyrimidin-2-yl)-3-[2-(2-dimethylcarbamoyl)phenylsulfamoyl]urea 2-{[({[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]amino}oxy)sulfinyl]amino}-N,N-dimethylbenzamide Not in list C15H18N6O6S O=C(Nc1nc(O)cc(OC)n1)NOS(=O)Nc2ccccc2C(=O)N(C)C InChI=1S/C15H18N6O6S/c1-21(2)13(23)9-6-4-5-7-10(9)20-28(25)27-19-15(24)18-14-16-11(22)8-12(17-14)26-3/h4-8,20H,1-3H3,(H3,16,17,18,19,22,24) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Italy Orthosulfamuron 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is a metabolite of the substance 1-(4-methoxy-6-hydroxypyrimidin-2-yl)-3-[2-(2-dimethylcarbamoyl)phenylsulfamoyl]urea 2-{[({[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]amino}oxy)sulfinyl]amino}-N,N-dimethylbenzamide Not in list C15H18N6O6S O=C(Nc1nc(O)cc(OC)n1)NOS(=O)Nc2ccccc2C(=O)N(C)C InChI=1S/C15H18N6O6S/c1-21(2)13(23)9-6-4-5-7-10(9)20-28(25)27-19-15(24)18-14-16-11(22)8-12(17-14)26-3/h4-8,20H,1-3H3,(H3,16,17,18,19,22,24) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Italy Orthosulfamuron 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is a metabolite of the substance 1-(4-methoxy-6-hydroxypyrimidin-2-yl)-3-[2-(2-dimethylcarbamoyl)phenylsulfamoyl]urea 2-{[({[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]amino}oxy)sulfinyl]amino}-N,N-dimethylbenzamide Not in list C15H18N6O6S O=C(Nc1nc(O)cc(OC)n1)NOS(=O)Nc2ccccc2C(=O)N(C)C InChI=1S/C15H18N6O6S/c1-21(2)13(23)9-6-4-5-7-10(9)20-28(25)27-19-15(24)18-14-16-11(22)8-12(17-14)26-3/h4-8,20H,1-3H3,(H3,16,17,18,19,22,24) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Italy Orthosulfamuron 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is a metabolite of the substance 1-(4-methoxy-6-hydroxypyrimidin-2-yl)-3-[2-(2-dimethylcarbamoyl)phenylsulfamoyl]urea 2-{[({[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]amino}oxy)sulfinyl]amino}-N,N-dimethylbenzamide Not in list C15H18N6O6S O=C(Nc1nc(O)cc(OC)n1)NOS(=O)Nc2ccccc2C(=O)N(C)C InChI=1S/C15H18N6O6S/c1-21(2)13(23)9-6-4-5-7-10(9)20-28(25)27-19-15(24)18-14-16-11(22)8-12(17-14)26-3/h4-8,20H,1-3H3,(H3,16,17,18,19,22,24) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female intraperitoneal 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Italy Orthosulfamuron 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is a metabolite of the substance 1-(4-methoxy-6-hydroxypyrimidin-2-yl)-3-[2-(2-dimethylcarbamoyl)phenylsulfamoyl]urea 2-{[({[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]amino}oxy)sulfinyl]amino}-N,N-dimethylbenzamide Not in list C15H18N6O6S O=C(Nc1nc(O)cc(OC)n1)NOS(=O)Nc2ccccc2C(=O)N(C)C InChI=1S/C15H18N6O6S/c1-21(2)13(23)9-6-4-5-7-10(9)20-28(25)27-19-15(24)18-14-16-11(22)8-12(17-14)26-3/h4-8,20H,1-3H3,(H3,16,17,18,19,22,24) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female intraperitoneal 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Italy Orthosulfamuron 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Phosmet 211-987-4 732-11-6 single chemical entity Component is identical to the substance Phosmet 211-987-4 732-11-6 S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate Phosmet C11H12NO4PS2 COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Spain Phosmet 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet 21Jun2006 2006 doi:10.2903/j.efsa.2006.75r
+Phosmet 211-987-4 732-11-6 single chemical entity Component is identical to the substance Phosmet 211-987-4 732-11-6 S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate Phosmet C11H12NO4PS2 COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Spain Phosmet 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet 21Jun2006 2006 doi:10.2903/j.efsa.2006.75r
+Phosmet 211-987-4 732-11-6 single chemical entity Component is identical to the substance Phosmet 211-987-4 732-11-6 S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate Phosmet C11H12NO4PS2 COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Spain Phosmet 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet 21Jun2006 2006 doi:10.2903/j.efsa.2006.75r
+Phosmet 211-987-4 732-11-6 single chemical entity Component is identical to the substance Phosmet 211-987-4 732-11-6 S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate Phosmet C11H12NO4PS2 COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Spain Phosmet 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet 21Jun2006 2006 doi:10.2903/j.efsa.2006.75r
+Phosmet 211-987-4 732-11-6 single chemical entity Component is identical to the substance Phosmet 211-987-4 732-11-6 S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate Phosmet C11H12NO4PS2 COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Positive RMS: Spain Phosmet 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet 21Jun2006 2006 doi:10.2903/j.efsa.2006.75r
+Phosmet 211-987-4 732-11-6 single chemical entity Component is identical to the substance Phosmet 211-987-4 732-11-6 S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate Phosmet C11H12NO4PS2 COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Spain Phosmet 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet 21Jun2006 2006 doi:10.2903/j.efsa.2006.75r
+Phosmet 211-987-4 732-11-6 single chemical entity Component is identical to the substance Phosmet 211-987-4 732-11-6 S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate Phosmet C11H12NO4PS2 COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Positive RMS: Spain Phosmet 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet 21Jun2006 2006 doi:10.2903/j.efsa.2006.75r
+Phosmet 211-987-4 732-11-6 single chemical entity Component is identical to the substance Phosmet 211-987-4 732-11-6 S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate Phosmet C11H12NO4PS2 COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Spain Phosmet 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet 21Jun2006 2006 doi:10.2903/j.efsa.2006.75r
+Phosmet 211-987-4 732-11-6 single chemical entity Component is identical to the substance Phosmet 211-987-4 732-11-6 S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate Phosmet C11H12NO4PS2 COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Spain Phosmet 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet 21Jun2006 2006 doi:10.2903/j.efsa.2006.75r
+Phosmet 211-987-4 732-11-6 single chemical entity Component is identical to the substance Phosmet 211-987-4 732-11-6 S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate Phosmet C11H12NO4PS2 COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Spain Phosmet 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet 21Jun2006 2006 doi:10.2903/j.efsa.2006.75r
+Phosmet 211-987-4 732-11-6 single chemical entity Component is identical to the substance Phosmet 211-987-4 732-11-6 S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate Phosmet C11H12NO4PS2 COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Spain Phosmet 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet 21Jun2006 2006 doi:10.2903/j.efsa.2006.75r
+Phosmet 211-987-4 732-11-6 single chemical entity Component is identical to the substance Phosmet 211-987-4 732-11-6 S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate Phosmet C11H12NO4PS2 COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Spain Phosmet 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet 21Jun2006 2006 doi:10.2903/j.efsa.2006.75r
+Phosmet 211-987-4 732-11-6 single chemical entity Component is identical to the substance Phosmet 211-987-4 732-11-6 S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate Phosmet C11H12NO4PS2 COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Spain Phosmet 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet 21Jun2006 2006 doi:10.2903/j.efsa.2006.75r
+Phosmet 211-987-4 732-11-6 single chemical entity Component is identical to the substance Phosmet 211-987-4 732-11-6 S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate Phosmet C11H12NO4PS2 COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Spain Phosmet 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet 21Jun2006 2006 doi:10.2903/j.efsa.2006.75r
+Phosmet 211-987-4 732-11-6 single chemical entity Component is identical to the substance Phosmet 211-987-4 732-11-6 S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate Phosmet C11H12NO4PS2 COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Spain Phosmet 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet 21Jun2006 2006 doi:10.2903/j.efsa.2006.75r
+Phosmet 211-987-4 732-11-6 single chemical entity Component is identical to the substance Phosmet 211-987-4 732-11-6 S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate Phosmet C11H12NO4PS2 COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Spain Phosmet 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet 21Jun2006 2006 doi:10.2903/j.efsa.2006.75r
+Phosmet 211-987-4 732-11-6 single chemical entity Component is identical to the substance Phosmet 211-987-4 732-11-6 S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate Phosmet C11H12NO4PS2 COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Spain Phosmet 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet 21Jun2006 2006 doi:10.2903/j.efsa.2006.75r
+Phosmet 211-987-4 732-11-6 single chemical entity Component is identical to the substance Phosmet 211-987-4 732-11-6 S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate Phosmet C11H12NO4PS2 COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Positive RMS: Spain Phosmet 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet 21Jun2006 2006 doi:10.2903/j.efsa.2006.75r
+Phosmet 211-987-4 732-11-6 single chemical entity Component is identical to the substance Phosmet 211-987-4 732-11-6 S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate Phosmet C11H12NO4PS2 COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Spain Phosmet 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet 21Jun2006 2006 doi:10.2903/j.efsa.2006.75r
+Phosmet 211-987-4 732-11-6 single chemical entity Component is identical to the substance Phosmet 211-987-4 732-11-6 S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate Phosmet C11H12NO4PS2 COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Positive RMS: Spain Phosmet 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet 21Jun2006 2006 doi:10.2903/j.efsa.2006.75r
+Phosmet 211-987-4 732-11-6 single chemical entity Component is identical to the substance Phosmet 211-987-4 732-11-6 S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate Phosmet C11H12NO4PS2 COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Spain Phosmet 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet 21Jun2006 2006 doi:10.2903/j.efsa.2006.75r
+Phosmet 211-987-4 732-11-6 single chemical entity Component is identical to the substance Phosmet 211-987-4 732-11-6 S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate Phosmet C11H12NO4PS2 COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Spain Phosmet 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet 21Jun2006 2006 doi:10.2903/j.efsa.2006.75r
+Phosmet 211-987-4 732-11-6 single chemical entity Component is identical to the substance Phosmet 211-987-4 732-11-6 S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate Phosmet C11H12NO4PS2 COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Spain Phosmet 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet 21Jun2006 2006 doi:10.2903/j.efsa.2006.75r
+Phosmet 211-987-4 732-11-6 single chemical entity Component is identical to the substance Phosmet 211-987-4 732-11-6 S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate Phosmet C11H12NO4PS2 COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle with Positive RMS: Spain Phosmet 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet 21Jun2006 2006 doi:10.2903/j.efsa.2006.75r
+Phosmet 211-987-4 732-11-6 single chemical entity Component is identical to the substance Phosmet 211-987-4 732-11-6 S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate Phosmet C11H12NO4PS2 COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Spain Phosmet 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet 21Jun2006 2006 doi:10.2903/j.efsa.2006.75r
+Phosmet 211-987-4 732-11-6 single chemical entity Component is identical to the substance Phosmet 211-987-4 732-11-6 S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate Phosmet C11H12NO4PS2 COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Positive RMS: Spain Phosmet 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet 21Jun2006 2006 doi:10.2903/j.efsa.2006.75r
+Phosmet 211-987-4 732-11-6 single chemical entity Component is identical to the substance Phosmet 211-987-4 732-11-6 S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate Phosmet C11H12NO4PS2 COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Spain Phosmet 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet 21Jun2006 2006 doi:10.2903/j.efsa.2006.75r
+Phosmet 211-987-4 732-11-6 single chemical entity Component is identical to the substance Phosmet 211-987-4 732-11-6 S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate Phosmet C11H12NO4PS2 COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Positive RMS: Spain Phosmet 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet 21Jun2006 2006 doi:10.2903/j.efsa.2006.75r
+Phosmet 211-987-4 732-11-6 single chemical entity Component is identical to the substance Phosmet 211-987-4 732-11-6 S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate Phosmet C11H12NO4PS2 COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle without Positive RMS: Spain Phosmet 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet 21Jun2006 2006 doi:10.2903/j.efsa.2006.75r
+Phosmet 211-987-4 732-11-6 single chemical entity Component is identical to the substance Phosmet 211-987-4 732-11-6 S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate Phosmet C11H12NO4PS2 COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Spain Phosmet 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet 21Jun2006 2006 doi:10.2903/j.efsa.2006.75r
+Phosmet 211-987-4 732-11-6 single chemical entity Component is identical to the substance Phosmet 211-987-4 732-11-6 S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate Phosmet C11H12NO4PS2 COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Positive no information RMS: Spain Phosmet 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet 21Jun2006 2006 doi:10.2903/j.efsa.2006.75r
+Phosmet 211-987-4 732-11-6 single chemical entity Component is identical to the substance Phosmet 211-987-4 732-11-6 S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate Phosmet C11H12NO4PS2 COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Negative no information RMS: Spain Phosmet 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet 21Jun2006 2006 doi:10.2903/j.efsa.2006.75r
+Phosmet 211-987-4 732-11-6 single chemical entity Component is identical to the substance Phosmet 211-987-4 732-11-6 S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate Phosmet C11H12NO4PS2 COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3 organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Positive no information RMS: Spain Phosmet 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet 21Jun2006 2006 doi:10.2903/j.efsa.2006.75r
+Phosmet 211-987-4 732-11-6 single chemical entity Component is identical to the substance Phosmet 211-987-4 732-11-6 S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate Phosmet C11H12NO4PS2 COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative RMS: Spain Phosmet 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet 21Jun2006 2006 doi:10.2903/j.efsa.2006.75r
+Phosmet 211-987-4 732-11-6 single chemical entity Component is identical to the substance Phosmet 211-987-4 732-11-6 S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate Phosmet C11H12NO4PS2 COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Negative RMS: Spain Phosmet 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet 21Jun2006 2006 doi:10.2903/j.efsa.2006.75r
+Phosmet 211-987-4 732-11-6 single chemical entity Component is identical to the substance Phosmet 211-987-4 732-11-6 S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate Phosmet C11H12NO4PS2 COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3 organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Positive no information RMS: Spain Phosmet 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet 21Jun2006 2006 doi:10.2903/j.efsa.2006.75r
+Phosmet 211-987-4 732-11-6 single chemical entity Component is identical to the substance Phosmet 211-987-4 732-11-6 S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate Phosmet C11H12NO4PS2 COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3 organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes no data Negative RMS: Spain Phosmet 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet 21Jun2006 2006 doi:10.2903/j.efsa.2006.75r
+Phosmet 211-987-4 732-11-6 single chemical entity Component is identical to the substance Phosmet 211-987-4 732-11-6 S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate Phosmet C11H12NO4PS2 COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3 organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes no data Negative RMS: Spain Phosmet 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet 21Jun2006 2006 doi:10.2903/j.efsa.2006.75r
+Phosmet 211-987-4 732-11-6 single chemical entity Component is identical to the substance Phosmet 211-987-4 732-11-6 S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate Phosmet C11H12NO4PS2 COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3 organic compound Other Other DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Human (as organism) fibroblast Not reported yes, concurrent vehicle with Negative RMS: Spain Phosmet 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet 21Jun2006 2006 doi:10.2903/j.efsa.2006.75r
+Phosmet 211-987-4 732-11-6 single chemical entity Component is identical to the substance Phosmet 211-987-4 732-11-6 S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate Phosmet C11H12NO4PS2 COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3 organic compound Other Other DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Human (as organism) fibroblast Not reported yes, concurrent vehicle without Negative RMS: Spain Phosmet 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet 21Jun2006 2006 doi:10.2903/j.efsa.2006.75r
+Phosmet 211-987-4 732-11-6 single chemical entity Component is identical to the substance Phosmet 211-987-4 732-11-6 S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate Phosmet C11H12NO4PS2 COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Spain Phosmet 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet 21Jun2006 2006 doi:10.2903/j.efsa.2006.75r
+Phosmet 211-987-4 732-11-6 single chemical entity Component is identical to the substance Phosmet 211-987-4 732-11-6 S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate Phosmet C11H12NO4PS2 COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Spain Phosmet 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet 21Jun2006 2006 doi:10.2903/j.efsa.2006.75r
+Phosmet 211-987-4 732-11-6 single chemical entity Component is identical to the substance Phosmet 211-987-4 732-11-6 S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate Phosmet C11H12NO4PS2 COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 72.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Spain Phosmet 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet 21Jun2006 2006 doi:10.2903/j.efsa.2006.75r
+Phosmet 211-987-4 732-11-6 single chemical entity Component is identical to the substance Phosmet 211-987-4 732-11-6 S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate Phosmet C11H12NO4PS2 COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Swiss 10 Male oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Spain Phosmet 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet 21Jun2006 2006 doi:10.2903/j.efsa.2006.75r
+Phosmet 211-987-4 732-11-6 single chemical entity Component is identical to the substance Phosmet 211-987-4 732-11-6 S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate Phosmet C11H12NO4PS2 COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3 organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo Equivalent or similar to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) Yes Acceptable Rat (as animal) Alpk:APf SD Rat 5 Male oral: gavage 2.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Spain Phosmet 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet 21Jun2006 2006 doi:10.2903/j.efsa.2006.75r
+Phosmet 211-987-4 732-11-6 single chemical entity Component is identical to the substance Phosmet 211-987-4 732-11-6 S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate Phosmet C11H12NO4PS2 COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3 organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo Equivalent or similar to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) Yes Acceptable Rat (as animal) Alpk:APf SD Rat 5 Male oral: gavage 16.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Spain Phosmet 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet 21Jun2006 2006 doi:10.2903/j.efsa.2006.75r
+Phosmet 211-987-4 732-11-6 single chemical entity Component is identical to the substance Phosmet 211-987-4 732-11-6 S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate Phosmet C11H12NO4PS2 COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3 organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Sprague-Dawley 4 Male oral: gavage 2.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Spain Phosmet 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet 21Jun2006 2006 doi:10.2903/j.efsa.2006.75r
+Phosmet 211-987-4 732-11-6 single chemical entity Component is identical to the substance Phosmet 211-987-4 732-11-6 S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate Phosmet C11H12NO4PS2 COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3 organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Sprague-Dawley 4 Male oral: gavage 14.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Spain Phosmet 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet 21Jun2006 2006 doi:10.2903/j.efsa.2006.75r
+Phosmet 211-987-4 732-11-6 single chemical entity Component is identical to the substance Phosmet 211-987-4 732-11-6 S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate Phosmet C11H12NO4PS2 COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3 organic compound Other Other DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) AB/Jena Halle House mouse 6 Male intraperitoneal 6.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Spain Phosmet 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet 21Jun2006 2006 doi:10.2903/j.efsa.2006.75r
+Phosmet 211-987-4 732-11-6 single chemical entity Component is identical to the substance Phosmet 211-987-4 732-11-6 S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate Phosmet C11H12NO4PS2 COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3 organic compound Other Other DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) AB/Jena Halle House mouse 6 Male intraperitoneal 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Spain Phosmet 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet 21Jun2006 2006 doi:10.2903/j.efsa.2006.75r
+Phosmet 211-987-4 732-11-6 single chemical entity Component is identical to the substance Phosmet 211-987-4 732-11-6 S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate Phosmet C11H12NO4PS2 COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3 organic compound Other Other DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) AB/Jena Halle House mouse 6 Male intraperitoneal 6.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Spain Phosmet 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet 21Jun2006 2006 doi:10.2903/j.efsa.2006.75r
+Phosmet 211-987-4 732-11-6 single chemical entity Component is identical to the substance Phosmet 211-987-4 732-11-6 S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate Phosmet C11H12NO4PS2 COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3 organic compound Other Other DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) AB/Jena Halle House mouse 6 Male intraperitoneal 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Spain Phosmet 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet 21Jun2006 2006 doi:10.2903/j.efsa.2006.75r
+Penthiopyrad 183675-82-3 single chemical entity Component is identical to the substance Penthiopyrad 183675-82-3 1-methyl-N-[2-(4-methylpentan-2-yl)thiophen-3-yl]-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide Penthiopyrad C16H20F3N3OS O=C(Nc1ccsc1C(C)CC(C)C)c2cn(C)nc2C(F)(F)F InChI=1S/C16H20F3N3OS/c1-9(2)7-10(3)13-12(5-6-24-13)20-15(23)11-8-22(4)21-14(11)16(17,18)19/h5-6,8-10H,7H2,1-4H3,(H,20,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) Not reported Not reported no data without Negative RMS: The United Kingdom Penthiopyrad 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad. 15Feb2013 2013 doi:10.2903/j.efsa.2013.3111
+Penthiopyrad 183675-82-3 single chemical entity Component is identical to the substance Penthiopyrad 183675-82-3 1-methyl-N-[2-(4-methylpentan-2-yl)thiophen-3-yl]-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide Penthiopyrad C16H20F3N3OS O=C(Nc1ccsc1C(C)CC(C)C)c2cn(C)nc2C(F)(F)F InChI=1S/C16H20F3N3OS/c1-9(2)7-10(3)13-12(5-6-24-13)20-15(23)11-8-22(4)21-14(11)16(17,18)19/h5-6,8-10H,7H2,1-4H3,(H,20,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) Not reported Not reported no data with Negative RMS: The United Kingdom Penthiopyrad 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad. 15Feb2013 2013 doi:10.2903/j.efsa.2013.3111
+Penthiopyrad 183675-82-3 single chemical entity Component is identical to the substance Penthiopyrad 183675-82-3 1-methyl-N-[2-(4-methylpentan-2-yl)thiophen-3-yl]-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide Penthiopyrad C16H20F3N3OS O=C(Nc1ccsc1C(C)CC(C)C)c2cn(C)nc2C(F)(F)F InChI=1S/C16H20F3N3OS/c1-9(2)7-10(3)13-12(5-6-24-13)20-15(23)11-8-22(4)21-14(11)16(17,18)19/h5-6,8-10H,7H2,1-4H3,(H,20,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) Not reported Not reported no data without Negative RMS: The United Kingdom Penthiopyrad 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad. 15Feb2013 2013 doi:10.2903/j.efsa.2013.3111
+Penthiopyrad 183675-82-3 single chemical entity Component is identical to the substance Penthiopyrad 183675-82-3 1-methyl-N-[2-(4-methylpentan-2-yl)thiophen-3-yl]-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide Penthiopyrad C16H20F3N3OS O=C(Nc1ccsc1C(C)CC(C)C)c2cn(C)nc2C(F)(F)F InChI=1S/C16H20F3N3OS/c1-9(2)7-10(3)13-12(5-6-24-13)20-15(23)11-8-22(4)21-14(11)16(17,18)19/h5-6,8-10H,7H2,1-4H3,(H,20,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) Not reported Not reported no data with Negative RMS: The United Kingdom Penthiopyrad 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad. 15Feb2013 2013 doi:10.2903/j.efsa.2013.3111
+Penthiopyrad 183675-82-3 single chemical entity Component is identical to the substance Penthiopyrad 183675-82-3 1-methyl-N-[2-(4-methylpentan-2-yl)thiophen-3-yl]-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide Penthiopyrad C16H20F3N3OS O=C(Nc1ccsc1C(C)CC(C)C)c2cn(C)nc2C(F)(F)F InChI=1S/C16H20F3N3OS/c1-9(2)7-10(3)13-12(5-6-24-13)20-15(23)11-8-22(4)21-14(11)16(17,18)19/h5-6,8-10H,7H2,1-4H3,(H,20,23) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data without Negative no information RMS: The United Kingdom Penthiopyrad 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad. 15Feb2013 2013 doi:10.2903/j.efsa.2013.3111
+Penthiopyrad 183675-82-3 single chemical entity Component is identical to the substance Penthiopyrad 183675-82-3 1-methyl-N-[2-(4-methylpentan-2-yl)thiophen-3-yl]-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide Penthiopyrad C16H20F3N3OS O=C(Nc1ccsc1C(C)CC(C)C)c2cn(C)nc2C(F)(F)F InChI=1S/C16H20F3N3OS/c1-9(2)7-10(3)13-12(5-6-24-13)20-15(23)11-8-22(4)21-14(11)16(17,18)19/h5-6,8-10H,7H2,1-4H3,(H,20,23) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data with Negative no information RMS: The United Kingdom Penthiopyrad 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad. 15Feb2013 2013 doi:10.2903/j.efsa.2013.3111
+Penthiopyrad 183675-82-3 single chemical entity Component is identical to the substance Penthiopyrad 183675-82-3 1-methyl-N-[2-(4-methylpentan-2-yl)thiophen-3-yl]-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide Penthiopyrad C16H20F3N3OS O=C(Nc1ccsc1C(C)CC(C)C)c2cn(C)nc2C(F)(F)F InChI=1S/C16H20F3N3OS/c1-9(2)7-10(3)13-12(5-6-24-13)20-15(23)11-8-22(4)21-14(11)16(17,18)19/h5-6,8-10H,7H2,1-4H3,(H,20,23) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data without Negative RMS: The United Kingdom Penthiopyrad 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad. 15Feb2013 2013 doi:10.2903/j.efsa.2013.3111
+Penthiopyrad 183675-82-3 single chemical entity Component is identical to the substance Penthiopyrad 183675-82-3 1-methyl-N-[2-(4-methylpentan-2-yl)thiophen-3-yl]-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide Penthiopyrad C16H20F3N3OS O=C(Nc1ccsc1C(C)CC(C)C)c2cn(C)nc2C(F)(F)F InChI=1S/C16H20F3N3OS/c1-9(2)7-10(3)13-12(5-6-24-13)20-15(23)11-8-22(4)21-14(11)16(17,18)19/h5-6,8-10H,7H2,1-4H3,(H,20,23) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data with Negative RMS: The United Kingdom Penthiopyrad 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad. 15Feb2013 2013 doi:10.2903/j.efsa.2013.3111
+Penthiopyrad 183675-82-3 single chemical entity Component is identical to the substance Penthiopyrad 183675-82-3 1-methyl-N-[2-(4-methylpentan-2-yl)thiophen-3-yl]-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide Penthiopyrad C16H20F3N3OS O=C(Nc1ccsc1C(C)CC(C)C)c2cn(C)nc2C(F)(F)F InChI=1S/C16H20F3N3OS/c1-9(2)7-10(3)13-12(5-6-24-13)20-15(23)11-8-22(4)21-14(11)16(17,18)19/h5-6,8-10H,7H2,1-4H3,(H,20,23) organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported no data without Negative RMS: The United Kingdom Penthiopyrad 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad. 15Feb2013 2013 doi:10.2903/j.efsa.2013.3111
+Penthiopyrad 183675-82-3 single chemical entity Component is identical to the substance Penthiopyrad 183675-82-3 1-methyl-N-[2-(4-methylpentan-2-yl)thiophen-3-yl]-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide Penthiopyrad C16H20F3N3OS O=C(Nc1ccsc1C(C)CC(C)C)c2cn(C)nc2C(F)(F)F InChI=1S/C16H20F3N3OS/c1-9(2)7-10(3)13-12(5-6-24-13)20-15(23)11-8-22(4)21-14(11)16(17,18)19/h5-6,8-10H,7H2,1-4H3,(H,20,23) organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported no data without Negative RMS: The United Kingdom Penthiopyrad 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad. 15Feb2013 2013 doi:10.2903/j.efsa.2013.3111
+Penthiopyrad 183675-82-3 single chemical entity Component is identical to the substance Penthiopyrad 183675-82-3 1-methyl-N-[2-(4-methylpentan-2-yl)thiophen-3-yl]-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide Penthiopyrad C16H20F3N3OS O=C(Nc1ccsc1C(C)CC(C)C)c2cn(C)nc2C(F)(F)F InChI=1S/C16H20F3N3OS/c1-9(2)7-10(3)13-12(5-6-24-13)20-15(23)11-8-22(4)21-14(11)16(17,18)19/h5-6,8-10H,7H2,1-4H3,(H,20,23) organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported no data with Negative RMS: The United Kingdom Penthiopyrad 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad. 15Feb2013 2013 doi:10.2903/j.efsa.2013.3111
+Penthiopyrad 183675-82-3 single chemical entity Component is identical to the substance Penthiopyrad 183675-82-3 1-methyl-N-[2-(4-methylpentan-2-yl)thiophen-3-yl]-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide Penthiopyrad C16H20F3N3OS O=C(Nc1ccsc1C(C)CC(C)C)c2cn(C)nc2C(F)(F)F InChI=1S/C16H20F3N3OS/c1-9(2)7-10(3)13-12(5-6-24-13)20-15(23)11-8-22(4)21-14(11)16(17,18)19/h5-6,8-10H,7H2,1-4H3,(H,20,23) organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported no data with Negative RMS: The United Kingdom Penthiopyrad 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad. 15Feb2013 2013 doi:10.2903/j.efsa.2013.3111
+Penthiopyrad 183675-82-3 single chemical entity Component is identical to the substance Penthiopyrad 183675-82-3 1-methyl-N-[2-(4-methylpentan-2-yl)thiophen-3-yl]-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide Penthiopyrad C16H20F3N3OS O=C(Nc1ccsc1C(C)CC(C)C)c2cn(C)nc2C(F)(F)F InChI=1S/C16H20F3N3OS/c1-9(2)7-10(3)13-12(5-6-24-13)20-15(23)11-8-22(4)21-14(11)16(17,18)19/h5-6,8-10H,7H2,1-4H3,(H,20,23) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Not reported No data Not reported yes not applicable Negative no evidence RMS: The United Kingdom Penthiopyrad 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad. 15Feb2013 2013 doi:10.2903/j.efsa.2013.3111
+Penthiopyrad 183675-82-3 single chemical entity Component is identical to the substance Penthiopyrad 183675-82-3 1-methyl-N-[2-(4-methylpentan-2-yl)thiophen-3-yl]-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide Penthiopyrad C16H20F3N3OS O=C(Nc1ccsc1C(C)CC(C)C)c2cn(C)nc2C(F)(F)F InChI=1S/C16H20F3N3OS/c1-9(2)7-10(3)13-12(5-6-24-13)20-15(23)11-8-22(4)21-14(11)16(17,18)19/h5-6,8-10H,7H2,1-4H3,(H,20,23) organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Not reported No data Not reported yes not applicable Negative RMS: The United Kingdom Penthiopyrad 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad. 15Feb2013 2013 doi:10.2903/j.efsa.2013.3111
+Penthiopyrad 183675-82-3 single chemical entity Component is a metabolite of the substance 3-Trifluoromethyl-1H-pyrazole-4-carboxylic acid 5-(Trifluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C5H3F3N2O2 C1=NNC(=C1C(=O)O)C(F)(F)F InChI=1S/C5H3F3N2O2/c6-5(7,8)3-2(4(11)12)1-9-10-3/h1H,(H,9,10)(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) Not reported Not reported no data without Negative RMS: The United Kingdom Penthiopyrad 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad. 15Feb2013 2013 doi:10.2903/j.efsa.2013.3111
+Penthiopyrad 183675-82-3 single chemical entity Component is a metabolite of the substance 3-Trifluoromethyl-1H-pyrazole-4-carboxylic acid 5-(Trifluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C5H3F3N2O2 C1=NNC(=C1C(=O)O)C(F)(F)F InChI=1S/C5H3F3N2O2/c6-5(7,8)3-2(4(11)12)1-9-10-3/h1H,(H,9,10)(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) Not reported Not reported no data with Negative RMS: The United Kingdom Penthiopyrad 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad. 15Feb2013 2013 doi:10.2903/j.efsa.2013.3111
+Penthiopyrad 183675-82-3 single chemical entity Component is a metabolite of the substance 3-Trifluoromethyl-1H-pyrazole-4-carboxylic acid 5-(Trifluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C5H3F3N2O2 C1=NNC(=C1C(=O)O)C(F)(F)F InChI=1S/C5H3F3N2O2/c6-5(7,8)3-2(4(11)12)1-9-10-3/h1H,(H,9,10)(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) Not reported Not reported no data without Negative RMS: The United Kingdom Penthiopyrad 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad. 15Feb2013 2013 doi:10.2903/j.efsa.2013.3111
+Penthiopyrad 183675-82-3 single chemical entity Component is a metabolite of the substance 3-Trifluoromethyl-1H-pyrazole-4-carboxylic acid 5-(Trifluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C5H3F3N2O2 C1=NNC(=C1C(=O)O)C(F)(F)F InChI=1S/C5H3F3N2O2/c6-5(7,8)3-2(4(11)12)1-9-10-3/h1H,(H,9,10)(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) Not reported Not reported no data with Negative RMS: The United Kingdom Penthiopyrad 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad. 15Feb2013 2013 doi:10.2903/j.efsa.2013.3111
+Penthiopyrad 183675-82-3 single chemical entity Component is a metabolite of the substance 3-Trifluoromethyl-1H-pyrazole-4-carboxylic acid 5-(Trifluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C5H3F3N2O2 C1=NNC(=C1C(=O)O)C(F)(F)F InChI=1S/C5H3F3N2O2/c6-5(7,8)3-2(4(11)12)1-9-10-3/h1H,(H,9,10)(H,11,12) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data with Negative RMS: The United Kingdom Penthiopyrad 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad. 15Feb2013 2013 doi:10.2903/j.efsa.2013.3111
+Penthiopyrad 183675-82-3 single chemical entity Component is a metabolite of the substance 3-Trifluoromethyl-1H-pyrazole-4-carboxylic acid 5-(Trifluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C5H3F3N2O2 C1=NNC(=C1C(=O)O)C(F)(F)F InChI=1S/C5H3F3N2O2/c6-5(7,8)3-2(4(11)12)1-9-10-3/h1H,(H,9,10)(H,11,12) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data without Negative RMS: The United Kingdom Penthiopyrad 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad. 15Feb2013 2013 doi:10.2903/j.efsa.2013.3111
+Penthiopyrad 183675-82-3 single chemical entity Component is a metabolite of the substance 3-Trifluoromethyl-1H-pyrazole-4-carboxylic acid 5-(Trifluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C5H3F3N2O2 C1=NNC(=C1C(=O)O)C(F)(F)F InChI=1S/C5H3F3N2O2/c6-5(7,8)3-2(4(11)12)1-9-10-3/h1H,(H,9,10)(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data without Negative no information RMS: The United Kingdom Penthiopyrad 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad. 15Feb2013 2013 doi:10.2903/j.efsa.2013.3111
+Penthiopyrad 183675-82-3 single chemical entity Component is a metabolite of the substance 3-Trifluoromethyl-1H-pyrazole-4-carboxylic acid 5-(Trifluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C5H3F3N2O2 C1=NNC(=C1C(=O)O)C(F)(F)F InChI=1S/C5H3F3N2O2/c6-5(7,8)3-2(4(11)12)1-9-10-3/h1H,(H,9,10)(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data with Negative no information RMS: The United Kingdom Penthiopyrad 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad. 15Feb2013 2013 doi:10.2903/j.efsa.2013.3111
+Penthiopyrad 183675-82-3 single chemical entity Component is a metabolite of the substance 1-Methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide 1-Methyl-3-(trifluoromethyl)pyrazole-4-carboxamide Not in list C6H6F3N3O CN1C=C(C(=N1)C(F)(F)F)C(=O)N InChI=1S/C6H6F3N3O/c1-12-2-3(5(10)13)4(11-12)6(7,8)9/h2H,1H3,(H2,10,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) Not reported Not reported no data with Negative RMS: The United Kingdom Penthiopyrad 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad. 15Feb2013 2013 doi:10.2903/j.efsa.2013.3111
+Penthiopyrad 183675-82-3 single chemical entity Component is a metabolite of the substance 1-Methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide 1-Methyl-3-(trifluoromethyl)pyrazole-4-carboxamide Not in list C6H6F3N3O CN1C=C(C(=N1)C(F)(F)F)C(=O)N InChI=1S/C6H6F3N3O/c1-12-2-3(5(10)13)4(11-12)6(7,8)9/h2H,1H3,(H2,10,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) Not reported Not reported no data without Negative RMS: The United Kingdom Penthiopyrad 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad. 15Feb2013 2013 doi:10.2903/j.efsa.2013.3111
+Penthiopyrad 183675-82-3 single chemical entity Component is a metabolite of the substance 1-Methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide 1-Methyl-3-(trifluoromethyl)pyrazole-4-carboxamide Not in list C6H6F3N3O CN1C=C(C(=N1)C(F)(F)F)C(=O)N InChI=1S/C6H6F3N3O/c1-12-2-3(5(10)13)4(11-12)6(7,8)9/h2H,1H3,(H2,10,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) Not reported Not reported no data with Negative RMS: The United Kingdom Penthiopyrad 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad. 15Feb2013 2013 doi:10.2903/j.efsa.2013.3111
+Penthiopyrad 183675-82-3 single chemical entity Component is a metabolite of the substance 1-Methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide 1-Methyl-3-(trifluoromethyl)pyrazole-4-carboxamide Not in list C6H6F3N3O CN1C=C(C(=N1)C(F)(F)F)C(=O)N InChI=1S/C6H6F3N3O/c1-12-2-3(5(10)13)4(11-12)6(7,8)9/h2H,1H3,(H2,10,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) Not reported Not reported no data without Negative RMS: The United Kingdom Penthiopyrad 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad. 15Feb2013 2013 doi:10.2903/j.efsa.2013.3111
+Penthiopyrad 183675-82-3 single chemical entity Component is a metabolite of the substance 1-Methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide 1-Methyl-3-(trifluoromethyl)pyrazole-4-carboxamide Not in list C6H6F3N3O CN1C=C(C(=N1)C(F)(F)F)C(=O)N InChI=1S/C6H6F3N3O/c1-12-2-3(5(10)13)4(11-12)6(7,8)9/h2H,1H3,(H2,10,13) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data without Positive RMS: The United Kingdom Penthiopyrad 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad. 15Feb2013 2013 doi:10.2903/j.efsa.2013.3111
+Penthiopyrad 183675-82-3 single chemical entity Component is a metabolite of the substance 1-Methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide 1-Methyl-3-(trifluoromethyl)pyrazole-4-carboxamide Not in list C6H6F3N3O CN1C=C(C(=N1)C(F)(F)F)C(=O)N InChI=1S/C6H6F3N3O/c1-12-2-3(5(10)13)4(11-12)6(7,8)9/h2H,1H3,(H2,10,13) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data with Negative RMS: The United Kingdom Penthiopyrad 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad. 15Feb2013 2013 doi:10.2903/j.efsa.2013.3111
+Penthiopyrad 183675-82-3 single chemical entity Component is a metabolite of the substance 1-Methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide 1-Methyl-3-(trifluoromethyl)pyrazole-4-carboxamide Not in list C6H6F3N3O CN1C=C(C(=N1)C(F)(F)F)C(=O)N InChI=1S/C6H6F3N3O/c1-12-2-3(5(10)13)4(11-12)6(7,8)9/h2H,1H3,(H2,10,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data without Positive no information RMS: The United Kingdom Penthiopyrad 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad. 15Feb2013 2013 doi:10.2903/j.efsa.2013.3111
+Penthiopyrad 183675-82-3 single chemical entity Component is a metabolite of the substance 1-Methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide 1-Methyl-3-(trifluoromethyl)pyrazole-4-carboxamide Not in list C6H6F3N3O CN1C=C(C(=N1)C(F)(F)F)C(=O)N InChI=1S/C6H6F3N3O/c1-12-2-3(5(10)13)4(11-12)6(7,8)9/h2H,1H3,(H2,10,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data with Negative no information RMS: The United Kingdom Penthiopyrad 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad. 15Feb2013 2013 doi:10.2903/j.efsa.2013.3111
+Penthiopyrad 183675-82-3 single chemical entity Component is a metabolite of the substance 1-Methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide 1-Methyl-3-(trifluoromethyl)pyrazole-4-carboxamide Not in list C6H6F3N3O CN1C=C(C(=N1)C(F)(F)F)C(=O)N InChI=1S/C6H6F3N3O/c1-12-2-3(5(10)13)4(11-12)6(7,8)9/h2H,1H3,(H2,10,13) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Not reported No data Not reported no data not applicable Negative no evidence RMS: The United Kingdom Penthiopyrad 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad. 15Feb2013 2013 doi:10.2903/j.efsa.2013.3111
+Penthiopyrad 183675-82-3 single chemical entity Component is a metabolite of the substance 1-Methyl-3-trifluoromethyl-1H-pyrazole-4-carboxylic acid 1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C6H5F3N2O2 FC(F)(F)c1nn(C)cc1C(=O)O InChI=1S/C6H5F3N2O2/c1-11-2-3(5(12)13)4(10-11)6(7,8)9/h2H,1H3,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) Not reported Not reported no data without Negative RMS: The United Kingdom Penthiopyrad 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad. 15Feb2013 2013 doi:10.2903/j.efsa.2013.3111
+Penthiopyrad 183675-82-3 single chemical entity Component is a metabolite of the substance 1-Methyl-3-trifluoromethyl-1H-pyrazole-4-carboxylic acid 1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C6H5F3N2O2 FC(F)(F)c1nn(C)cc1C(=O)O InChI=1S/C6H5F3N2O2/c1-11-2-3(5(12)13)4(10-11)6(7,8)9/h2H,1H3,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) Not reported Not reported no data with Negative RMS: The United Kingdom Penthiopyrad 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad. 15Feb2013 2013 doi:10.2903/j.efsa.2013.3111
+Penthiopyrad 183675-82-3 single chemical entity Component is a metabolite of the substance 1-Methyl-3-trifluoromethyl-1H-pyrazole-4-carboxylic acid 1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C6H5F3N2O2 FC(F)(F)c1nn(C)cc1C(=O)O InChI=1S/C6H5F3N2O2/c1-11-2-3(5(12)13)4(10-11)6(7,8)9/h2H,1H3,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) Not reported Not reported no data without Negative RMS: The United Kingdom Penthiopyrad 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad. 15Feb2013 2013 doi:10.2903/j.efsa.2013.3111
+Penthiopyrad 183675-82-3 single chemical entity Component is a metabolite of the substance 1-Methyl-3-trifluoromethyl-1H-pyrazole-4-carboxylic acid 1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C6H5F3N2O2 FC(F)(F)c1nn(C)cc1C(=O)O InChI=1S/C6H5F3N2O2/c1-11-2-3(5(12)13)4(10-11)6(7,8)9/h2H,1H3,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) Not reported Not reported no data with Negative RMS: The United Kingdom Penthiopyrad 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad. 15Feb2013 2013 doi:10.2903/j.efsa.2013.3111
+Penthiopyrad 183675-82-3 single chemical entity Component is a metabolite of the substance 1-Methyl-3-trifluoromethyl-1H-pyrazole-4-carboxylic acid 1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C6H5F3N2O2 FC(F)(F)c1nn(C)cc1C(=O)O InChI=1S/C6H5F3N2O2/c1-11-2-3(5(12)13)4(10-11)6(7,8)9/h2H,1H3,(H,12,13) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data with Negative RMS: The United Kingdom Penthiopyrad 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad. 15Feb2013 2013 doi:10.2903/j.efsa.2013.3111
+Penthiopyrad 183675-82-3 single chemical entity Component is a metabolite of the substance 1-Methyl-3-trifluoromethyl-1H-pyrazole-4-carboxylic acid 1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C6H5F3N2O2 FC(F)(F)c1nn(C)cc1C(=O)O InChI=1S/C6H5F3N2O2/c1-11-2-3(5(12)13)4(10-11)6(7,8)9/h2H,1H3,(H,12,13) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data without Negative RMS: The United Kingdom Penthiopyrad 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad. 15Feb2013 2013 doi:10.2903/j.efsa.2013.3111
+Penthiopyrad 183675-82-3 single chemical entity Component is a metabolite of the substance 1-Methyl-3-trifluoromethyl-1H-pyrazole-4-carboxylic acid 1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C6H5F3N2O2 FC(F)(F)c1nn(C)cc1C(=O)O InChI=1S/C6H5F3N2O2/c1-11-2-3(5(12)13)4(10-11)6(7,8)9/h2H,1H3,(H,12,13) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data without Negative no information RMS: The United Kingdom Penthiopyrad 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad. 15Feb2013 2013 doi:10.2903/j.efsa.2013.3111
+Penthiopyrad 183675-82-3 single chemical entity Component is a metabolite of the substance 1-Methyl-3-trifluoromethyl-1H-pyrazole-4-carboxylic acid 1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C6H5F3N2O2 FC(F)(F)c1nn(C)cc1C(=O)O InChI=1S/C6H5F3N2O2/c1-11-2-3(5(12)13)4(10-11)6(7,8)9/h2H,1H3,(H,12,13) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data with Negative no information RMS: The United Kingdom Penthiopyrad 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad. 15Feb2013 2013 doi:10.2903/j.efsa.2013.3111
+Penthiopyrad 183675-82-3 single chemical entity Component is a metabolite of the substance 1-Methyl-3-trifluoromethyl-1H-pyrazole-4-carboxylic acid 1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C6H5F3N2O2 FC(F)(F)c1nn(C)cc1C(=O)O InChI=1S/C6H5F3N2O2/c1-11-2-3(5(12)13)4(10-11)6(7,8)9/h2H,1H3,(H,12,13) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Not reported No data Not reported no data not applicable Negative RMS: The United Kingdom Penthiopyrad 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad. 15Feb2013 2013 doi:10.2903/j.efsa.2013.3111
+Penthiopyrad 183675-82-3 single chemical entity Component is a metabolite of the substance N-[2-(3-hydroxy-1,3-dimethylbutyl) thiophen-3-yl]-1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide N-[2-(4-hydroxy-4-methylpentan-2-yl)thiophen-3-yl]-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide Not in list C16H20F3N3O2S O=C(Nc1ccsc1C(C)CC(C)(C)O)c2cn(C)nc2C(F)(F)F InChI=1S/C16H20F3N3O2S/c1-9(7-15(2,3)24)12-11(5-6-25-12)20-14(23)10-8-22(4)21-13(10)16(17,18)19/h5-6,8-9,24H,7H2,1-4H3,(H,20,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) Not reported Not reported no data with Negative RMS: The United Kingdom Penthiopyrad 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad. 15Feb2013 2013 doi:10.2903/j.efsa.2013.3111
+Penthiopyrad 183675-82-3 single chemical entity Component is a metabolite of the substance N-[2-(3-hydroxy-1,3-dimethylbutyl) thiophen-3-yl]-1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide N-[2-(4-hydroxy-4-methylpentan-2-yl)thiophen-3-yl]-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide Not in list C16H20F3N3O2S O=C(Nc1ccsc1C(C)CC(C)(C)O)c2cn(C)nc2C(F)(F)F InChI=1S/C16H20F3N3O2S/c1-9(7-15(2,3)24)12-11(5-6-25-12)20-14(23)10-8-22(4)21-13(10)16(17,18)19/h5-6,8-9,24H,7H2,1-4H3,(H,20,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) Not reported Not reported no data with Negative RMS: The United Kingdom Penthiopyrad 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad. 15Feb2013 2013 doi:10.2903/j.efsa.2013.3111
+Penthiopyrad 183675-82-3 single chemical entity Component is a metabolite of the substance N-[2-(3-hydroxy-1,3-dimethylbutyl) thiophen-3-yl]-1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide N-[2-(4-hydroxy-4-methylpentan-2-yl)thiophen-3-yl]-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide Not in list C16H20F3N3O2S O=C(Nc1ccsc1C(C)CC(C)(C)O)c2cn(C)nc2C(F)(F)F InChI=1S/C16H20F3N3O2S/c1-9(7-15(2,3)24)12-11(5-6-25-12)20-14(23)10-8-22(4)21-13(10)16(17,18)19/h5-6,8-9,24H,7H2,1-4H3,(H,20,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) Not reported Not reported no data without Negative RMS: The United Kingdom Penthiopyrad 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad. 15Feb2013 2013 doi:10.2903/j.efsa.2013.3111
+Penthiopyrad 183675-82-3 single chemical entity Component is a metabolite of the substance N-[2-(3-hydroxy-1,3-dimethylbutyl) thiophen-3-yl]-1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide N-[2-(4-hydroxy-4-methylpentan-2-yl)thiophen-3-yl]-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide Not in list C16H20F3N3O2S O=C(Nc1ccsc1C(C)CC(C)(C)O)c2cn(C)nc2C(F)(F)F InChI=1S/C16H20F3N3O2S/c1-9(7-15(2,3)24)12-11(5-6-25-12)20-14(23)10-8-22(4)21-13(10)16(17,18)19/h5-6,8-9,24H,7H2,1-4H3,(H,20,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) Not reported Not reported no data without Negative RMS: The United Kingdom Penthiopyrad 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad. 15Feb2013 2013 doi:10.2903/j.efsa.2013.3111
+Penthiopyrad 183675-82-3 single chemical entity Component is a metabolite of the substance N-[2-(3-hydroxy-1,3-dimethylbutyl) thiophen-3-yl]-1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide N-[2-(4-hydroxy-4-methylpentan-2-yl)thiophen-3-yl]-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide Not in list C16H20F3N3O2S O=C(Nc1ccsc1C(C)CC(C)(C)O)c2cn(C)nc2C(F)(F)F InChI=1S/C16H20F3N3O2S/c1-9(7-15(2,3)24)12-11(5-6-25-12)20-14(23)10-8-22(4)21-13(10)16(17,18)19/h5-6,8-9,24H,7H2,1-4H3,(H,20,23) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data without Negative RMS: The United Kingdom Penthiopyrad 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad. 15Feb2013 2013 doi:10.2903/j.efsa.2013.3111
+Penthiopyrad 183675-82-3 single chemical entity Component is a metabolite of the substance N-[2-(3-hydroxy-1,3-dimethylbutyl) thiophen-3-yl]-1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide N-[2-(4-hydroxy-4-methylpentan-2-yl)thiophen-3-yl]-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide Not in list C16H20F3N3O2S O=C(Nc1ccsc1C(C)CC(C)(C)O)c2cn(C)nc2C(F)(F)F InChI=1S/C16H20F3N3O2S/c1-9(7-15(2,3)24)12-11(5-6-25-12)20-14(23)10-8-22(4)21-13(10)16(17,18)19/h5-6,8-9,24H,7H2,1-4H3,(H,20,23) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data with Negative RMS: The United Kingdom Penthiopyrad 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad. 15Feb2013 2013 doi:10.2903/j.efsa.2013.3111
+Penthiopyrad 183675-82-3 single chemical entity Component is a metabolite of the substance N-[2-(3-hydroxy-1,3-dimethylbutyl) thiophen-3-yl]-1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide N-[2-(4-hydroxy-4-methylpentan-2-yl)thiophen-3-yl]-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide Not in list C16H20F3N3O2S O=C(Nc1ccsc1C(C)CC(C)(C)O)c2cn(C)nc2C(F)(F)F InChI=1S/C16H20F3N3O2S/c1-9(7-15(2,3)24)12-11(5-6-25-12)20-14(23)10-8-22(4)21-13(10)16(17,18)19/h5-6,8-9,24H,7H2,1-4H3,(H,20,23) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no without Negative no information RMS: The United Kingdom Penthiopyrad 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad. 15Feb2013 2013 doi:10.2903/j.efsa.2013.3111
+Penthiopyrad 183675-82-3 single chemical entity Component is a metabolite of the substance N-[2-(3-hydroxy-1,3-dimethylbutyl) thiophen-3-yl]-1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide N-[2-(4-hydroxy-4-methylpentan-2-yl)thiophen-3-yl]-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide Not in list C16H20F3N3O2S O=C(Nc1ccsc1C(C)CC(C)(C)O)c2cn(C)nc2C(F)(F)F InChI=1S/C16H20F3N3O2S/c1-9(7-15(2,3)24)12-11(5-6-25-12)20-14(23)10-8-22(4)21-13(10)16(17,18)19/h5-6,8-9,24H,7H2,1-4H3,(H,20,23) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no with Negative no information RMS: The United Kingdom Penthiopyrad 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad. 15Feb2013 2013 doi:10.2903/j.efsa.2013.3111
+Penthiopyrad 183675-82-3 single chemical entity Component is a metabolite of the substance N-[5-hydroxy-5-(1,3-dimethylbutyl)-2-oxo-2,5-dihydrothiophen-4-yl]-1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide N-[2-hydroxy-2-(4-methylpentan-2-yl)-5-oxo-2,5-dihydrothiophen-3-yl]-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide Not in list C16H20F3N3O3S OC2(SC(=O)C=C2NC(=O)c1cn(C)nc1C(F)(F)F)C(C)CC(C)C InChI=1S/C16H20F3N3O3S/c1-8(2)5-9(3)15(25)11(6-12(23)26-15)20-14(24)10-7-22(4)21-13(10)16(17,18)19/h6-9,25H,5H2,1-4H3,(H,20,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) Not reported Not reported no data without Negative RMS: The United Kingdom Penthiopyrad 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad. 15Feb2013 2013 doi:10.2903/j.efsa.2013.3111
+Penthiopyrad 183675-82-3 single chemical entity Component is a metabolite of the substance N-[5-hydroxy-5-(1,3-dimethylbutyl)-2-oxo-2,5-dihydrothiophen-4-yl]-1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide N-[2-hydroxy-2-(4-methylpentan-2-yl)-5-oxo-2,5-dihydrothiophen-3-yl]-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide Not in list C16H20F3N3O3S OC2(SC(=O)C=C2NC(=O)c1cn(C)nc1C(F)(F)F)C(C)CC(C)C InChI=1S/C16H20F3N3O3S/c1-8(2)5-9(3)15(25)11(6-12(23)26-15)20-14(24)10-7-22(4)21-13(10)16(17,18)19/h6-9,25H,5H2,1-4H3,(H,20,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) Not reported Not reported no data with Negative RMS: The United Kingdom Penthiopyrad 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad. 15Feb2013 2013 doi:10.2903/j.efsa.2013.3111
+Penthiopyrad 183675-82-3 single chemical entity Component is a metabolite of the substance N-[5-hydroxy-5-(1,3-dimethylbutyl)-2-oxo-2,5-dihydrothiophen-4-yl]-1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide N-[2-hydroxy-2-(4-methylpentan-2-yl)-5-oxo-2,5-dihydrothiophen-3-yl]-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide Not in list C16H20F3N3O3S OC2(SC(=O)C=C2NC(=O)c1cn(C)nc1C(F)(F)F)C(C)CC(C)C InChI=1S/C16H20F3N3O3S/c1-8(2)5-9(3)15(25)11(6-12(23)26-15)20-14(24)10-7-22(4)21-13(10)16(17,18)19/h6-9,25H,5H2,1-4H3,(H,20,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) Not reported Not reported no data without Negative RMS: The United Kingdom Penthiopyrad 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad. 15Feb2013 2013 doi:10.2903/j.efsa.2013.3111
+Penthiopyrad 183675-82-3 single chemical entity Component is a metabolite of the substance N-[5-hydroxy-5-(1,3-dimethylbutyl)-2-oxo-2,5-dihydrothiophen-4-yl]-1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide N-[2-hydroxy-2-(4-methylpentan-2-yl)-5-oxo-2,5-dihydrothiophen-3-yl]-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide Not in list C16H20F3N3O3S OC2(SC(=O)C=C2NC(=O)c1cn(C)nc1C(F)(F)F)C(C)CC(C)C InChI=1S/C16H20F3N3O3S/c1-8(2)5-9(3)15(25)11(6-12(23)26-15)20-14(24)10-7-22(4)21-13(10)16(17,18)19/h6-9,25H,5H2,1-4H3,(H,20,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) Not reported Not reported no data with Negative RMS: The United Kingdom Penthiopyrad 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad. 15Feb2013 2013 doi:10.2903/j.efsa.2013.3111
+Penthiopyrad 183675-82-3 single chemical entity Component is a metabolite of the substance N-[5-hydroxy-5-(1,3-dimethylbutyl)-2-oxo-2,5-dihydrothiophen-4-yl]-1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide N-[2-hydroxy-2-(4-methylpentan-2-yl)-5-oxo-2,5-dihydrothiophen-3-yl]-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide Not in list C16H20F3N3O3S OC2(SC(=O)C=C2NC(=O)c1cn(C)nc1C(F)(F)F)C(C)CC(C)C InChI=1S/C16H20F3N3O3S/c1-8(2)5-9(3)15(25)11(6-12(23)26-15)20-14(24)10-7-22(4)21-13(10)16(17,18)19/h6-9,25H,5H2,1-4H3,(H,20,24) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data without Negative RMS: The United Kingdom Penthiopyrad 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad. 15Feb2013 2013 doi:10.2903/j.efsa.2013.3111
+Penthiopyrad 183675-82-3 single chemical entity Component is a metabolite of the substance N-[5-hydroxy-5-(1,3-dimethylbutyl)-2-oxo-2,5-dihydrothiophen-4-yl]-1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide N-[2-hydroxy-2-(4-methylpentan-2-yl)-5-oxo-2,5-dihydrothiophen-3-yl]-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide Not in list C16H20F3N3O3S OC2(SC(=O)C=C2NC(=O)c1cn(C)nc1C(F)(F)F)C(C)CC(C)C InChI=1S/C16H20F3N3O3S/c1-8(2)5-9(3)15(25)11(6-12(23)26-15)20-14(24)10-7-22(4)21-13(10)16(17,18)19/h6-9,25H,5H2,1-4H3,(H,20,24) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data with Negative RMS: The United Kingdom Penthiopyrad 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad. 15Feb2013 2013 doi:10.2903/j.efsa.2013.3111
+Penthiopyrad 183675-82-3 single chemical entity Component is a metabolite of the substance N-[5-hydroxy-5-(1,3-dimethylbutyl)-2-oxo-2,5-dihydrothiophen-4-yl]-1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide N-[2-hydroxy-2-(4-methylpentan-2-yl)-5-oxo-2,5-dihydrothiophen-3-yl]-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide Not in list C16H20F3N3O3S OC2(SC(=O)C=C2NC(=O)c1cn(C)nc1C(F)(F)F)C(C)CC(C)C InChI=1S/C16H20F3N3O3S/c1-8(2)5-9(3)15(25)11(6-12(23)26-15)20-14(24)10-7-22(4)21-13(10)16(17,18)19/h6-9,25H,5H2,1-4H3,(H,20,24) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data without Negative no information RMS: The United Kingdom Penthiopyrad 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad. 15Feb2013 2013 doi:10.2903/j.efsa.2013.3111
+Penthiopyrad 183675-82-3 single chemical entity Component is a metabolite of the substance N-[5-hydroxy-5-(1,3-dimethylbutyl)-2-oxo-2,5-dihydrothiophen-4-yl]-1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide N-[2-hydroxy-2-(4-methylpentan-2-yl)-5-oxo-2,5-dihydrothiophen-3-yl]-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide Not in list C16H20F3N3O3S OC2(SC(=O)C=C2NC(=O)c1cn(C)nc1C(F)(F)F)C(C)CC(C)C InChI=1S/C16H20F3N3O3S/c1-8(2)5-9(3)15(25)11(6-12(23)26-15)20-14(24)10-7-22(4)21-13(10)16(17,18)19/h6-9,25H,5H2,1-4H3,(H,20,24) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data with Negative no information RMS: The United Kingdom Penthiopyrad 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad. 15Feb2013 2013 doi:10.2903/j.efsa.2013.3111
+Penthiopyrad 183675-82-3 single chemical entity Component is a metabolite of the substance 1-Methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide 1-Methyl-3-(trifluoromethyl)pyrazole-4-carboxamide Not in list C6H6F3N3O CN1C=C(C(=N1)C(F)(F)F)C(=O)N InChI=1S/C6H6F3N3O/c1-12-2-3(5(10)13)4(11-12)6(7,8)9/h2H,1H3,(H2,10,13) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo According to OECD Guideline 489 No Acceptable Rat (as animal) Crj:CD(SD) 10 Male/Female oral: gavage 3.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Penthiopyrad (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad. 15Feb2013 2013 doi:10.2903/j.efsa.2013.3111
+Penthiopyrad 183675-82-3 single chemical entity Component is a metabolite of the substance 1-Methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide 1-Methyl-3-(trifluoromethyl)pyrazole-4-carboxamide Not in list C6H6F3N3O CN1C=C(C(=N1)C(F)(F)F)C(=O)N InChI=1S/C6H6F3N3O/c1-12-2-3(5(10)13)4(11-12)6(7,8)9/h2H,1H3,(H2,10,13) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo According to OECD Guideline 489 No Acceptable Rat (as animal) Crj:CD(SD) 10 Male/Female oral: gavage 3.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Penthiopyrad (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad. 15Feb2013 2013 doi:10.2903/j.efsa.2013.3111
+Potassium phosphonates mixture or formulation Component is identical to the substance Potassium phosphonates tripotassium;phosphite Not in list K3O3P [O-]P([O-])[O-].[K+].[K+].[K+] InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: France Potassium phosphite 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates 18Dec2012 2012 doi:10.2903/j.efsa.2012.2963
+Potassium phosphonates mixture or formulation Component is identical to the substance Potassium phosphonates tripotassium;phosphite Not in list K3O3P [O-]P([O-])[O-].[K+].[K+].[K+] InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: France Potassium phosphite 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates 18Dec2012 2012 doi:10.2903/j.efsa.2012.2963
+Potassium phosphonates mixture or formulation Component is identical to the substance Potassium phosphonates tripotassium;phosphite Not in list K3O3P [O-]P([O-])[O-].[K+].[K+].[K+] InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: France Potassium phosphite 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates 18Dec2012 2012 doi:10.2903/j.efsa.2012.2963
+Potassium phosphonates mixture or formulation Component is identical to the substance Potassium phosphonates tripotassium;phosphite Not in list K3O3P [O-]P([O-])[O-].[K+].[K+].[K+] InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: France Potassium phosphite 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates 18Dec2012 2012 doi:10.2903/j.efsa.2012.2963
+Fosetyl-aluminium 254-320-2 39148-24-8 single chemical entity Component is identical to the substance Fosetyl-aluminium 254-320-2 39148-24-8 Aluminum;ethoxy-oxido-oxophosphanium Fosetyl-aluminium C6H15AlO9P3+3 CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3] InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3 organometallic compound PubChem canonical SMILES PubChem InChI gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) DNA-polymerase-A-deficient Not reported yes without Negative RMS: France Fosetyl-Al 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl 18Jan2006 2006 doi:10.2903/j.efsa.2006.54r
+Potassium phosphonates mixture or formulation Component is identical to the substance Potassium phosphonates tripotassium;phosphite Not in list K3O3P [O-]P([O-])[O-].[K+].[K+].[K+] InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: France Potassium phosphite 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates 18Dec2012 2012 doi:10.2903/j.efsa.2012.2963
+Potassium phosphonates mixture or formulation Component is identical to the substance Potassium phosphonates tripotassium;phosphite Not in list K3O3P [O-]P([O-])[O-].[K+].[K+].[K+] InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) DNA-polymerase-A-proficient Not reported yes without Negative RMS: France Potassium phosphite 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates 18Dec2012 2012 doi:10.2903/j.efsa.2012.2963
+Potassium phosphonates mixture or formulation Component is identical to the substance Potassium phosphonates tripotassium;phosphite Not in list K3O3P [O-]P([O-])[O-].[K+].[K+].[K+] InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: France Potassium phosphite 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates 18Dec2012 2012 doi:10.2903/j.efsa.2012.2963
+Potassium phosphonates mixture or formulation Component is identical to the substance Potassium phosphonates tripotassium;phosphite Not in list K3O3P [O-]P([O-])[O-].[K+].[K+].[K+] InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Saccharomyces cerevisiae (as organism) D7 Not reported yes with Negative RMS: France Potassium phosphite 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates 18Dec2012 2012 doi:10.2903/j.efsa.2012.2963
+Potassium phosphonates mixture or formulation Component is identical to the substance Potassium phosphonates tripotassium;phosphite Not in list K3O3P [O-]P([O-])[O-].[K+].[K+].[K+] InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Saccharomyces cerevisiae (as organism) D7 Not reported yes without Negative RMS: France Potassium phosphite 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates 18Dec2012 2012 doi:10.2903/j.efsa.2012.2963
+Fosetyl-aluminium 254-320-2 39148-24-8 single chemical entity Component is identical to the substance Fosetyl-aluminium 254-320-2 39148-24-8 Aluminum;ethoxy-oxido-oxophosphanium Fosetyl-aluminium C6H15AlO9P3+3 CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3] InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3 organometallic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: France Fosetyl-Al 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl 18Jan2006 2006 doi:10.2903/j.efsa.2006.54r
+Potassium phosphonates mixture or formulation Component is identical to the substance Potassium phosphonates tripotassium;phosphite Not in list K3O3P [O-]P([O-])[O-].[K+].[K+].[K+] InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) DNA-polymerase-A-proficient Not reported yes with Negative RMS: France Potassium phosphite 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates 18Dec2012 2012 doi:10.2903/j.efsa.2012.2963
+Potassium phosphonates mixture or formulation Component is identical to the substance Potassium phosphonates tripotassium;phosphite Not in list K3O3P [O-]P([O-])[O-].[K+].[K+].[K+] InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) DNA-polymerase-A-deficient Not reported yes with Negative RMS: France Potassium phosphite 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates 18Dec2012 2012 doi:10.2903/j.efsa.2012.2963
+Potassium phosphonates mixture or formulation Component is identical to the substance Potassium phosphonates tripotassium;phosphite Not in list K3O3P [O-]P([O-])[O-].[K+].[K+].[K+] InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) K12 Not reported yes with Negative RMS: France Potassium phosphite 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates 18Dec2012 2012 doi:10.2903/j.efsa.2012.2963
+Fosetyl-aluminium 254-320-2 39148-24-8 single chemical entity Component is identical to the substance Fosetyl-aluminium 254-320-2 39148-24-8 Aluminum;ethoxy-oxido-oxophosphanium Fosetyl-aluminium C6H15AlO9P3+3 CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3] InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3 organometallic compound PubChem canonical SMILES PubChem InChI gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) DNA-polymerase-A-proficient Not reported yes without Negative RMS: France Fosetyl-Al 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl 18Jan2006 2006 doi:10.2903/j.efsa.2006.54r
+Potassium phosphonates mixture or formulation Component is identical to the substance Potassium phosphonates tripotassium;phosphite Not in list K3O3P [O-]P([O-])[O-].[K+].[K+].[K+] InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) K12 Not reported yes without Negative RMS: France Potassium phosphite 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates 18Dec2012 2012 doi:10.2903/j.efsa.2012.2963
+Fosetyl-aluminium 254-320-2 39148-24-8 single chemical entity Component is identical to the substance Fosetyl-aluminium 254-320-2 39148-24-8 Aluminum;ethoxy-oxido-oxophosphanium Fosetyl-aluminium C6H15AlO9P3+3 CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3] InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3 organometallic compound PubChem canonical SMILES PubChem InChI gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Saccharomyces cerevisiae (as organism) D7 Not reported yes with Negative RMS: France Fosetyl-Al 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl 18Jan2006 2006 doi:10.2903/j.efsa.2006.54r
+Fosetyl-aluminium 254-320-2 39148-24-8 single chemical entity Component is identical to the substance Fosetyl-aluminium 254-320-2 39148-24-8 Aluminum;ethoxy-oxido-oxophosphanium Fosetyl-aluminium C6H15AlO9P3+3 CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3] InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3 organometallic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: France Fosetyl-Al 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl 18Jan2006 2006 doi:10.2903/j.efsa.2006.54r
+Potassium phosphonates mixture or formulation Component is identical to the substance Potassium phosphonates tripotassium;phosphite Not in list K3O3P [O-]P([O-])[O-].[K+].[K+].[K+] InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: France Potassium phosphite 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates 18Dec2012 2012 doi:10.2903/j.efsa.2012.2963
+Potassium phosphonates mixture or formulation Component is identical to the substance Potassium phosphonates tripotassium;phosphite Not in list K3O3P [O-]P([O-])[O-].[K+].[K+].[K+] InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: France Potassium phosphite 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates 18Dec2012 2012 doi:10.2903/j.efsa.2012.2963
+Fosetyl-aluminium 254-320-2 39148-24-8 single chemical entity Component is identical to the substance Fosetyl-aluminium 254-320-2 39148-24-8 Aluminum;ethoxy-oxido-oxophosphanium Fosetyl-aluminium C6H15AlO9P3+3 CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3] InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3 organometallic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) K12 Not reported yes without Negative RMS: France Fosetyl-Al 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl 18Jan2006 2006 doi:10.2903/j.efsa.2006.54r
+Fosetyl-aluminium 254-320-2 39148-24-8 single chemical entity Component is identical to the substance Fosetyl-aluminium 254-320-2 39148-24-8 Aluminum;ethoxy-oxido-oxophosphanium Fosetyl-aluminium C6H15AlO9P3+3 CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3] InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3 organometallic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: France Fosetyl-Al 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl 18Jan2006 2006 doi:10.2903/j.efsa.2006.54r
+Fosetyl-aluminium 254-320-2 39148-24-8 single chemical entity Component is identical to the substance Fosetyl-aluminium 254-320-2 39148-24-8 Aluminum;ethoxy-oxido-oxophosphanium Fosetyl-aluminium C6H15AlO9P3+3 CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3] InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3 organometallic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: France Fosetyl-Al 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl 18Jan2006 2006 doi:10.2903/j.efsa.2006.54r
+Fosetyl-aluminium 254-320-2 39148-24-8 single chemical entity Component is identical to the substance Fosetyl-aluminium 254-320-2 39148-24-8 Aluminum;ethoxy-oxido-oxophosphanium Fosetyl-aluminium C6H15AlO9P3+3 CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3] InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3 organometallic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: France Fosetyl-Al 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl 18Jan2006 2006 doi:10.2903/j.efsa.2006.54r
+Fosetyl-aluminium 254-320-2 39148-24-8 single chemical entity Component is identical to the substance Fosetyl-aluminium 254-320-2 39148-24-8 Aluminum;ethoxy-oxido-oxophosphanium Fosetyl-aluminium C6H15AlO9P3+3 CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3] InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3 organometallic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) K12 Not reported yes with Negative RMS: France Fosetyl-Al 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl 18Jan2006 2006 doi:10.2903/j.efsa.2006.54r
+Fosetyl-aluminium 254-320-2 39148-24-8 single chemical entity Component is identical to the substance Fosetyl-aluminium 254-320-2 39148-24-8 Aluminum;ethoxy-oxido-oxophosphanium Fosetyl-aluminium C6H15AlO9P3+3 CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3] InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3 organometallic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: France Fosetyl-Al 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl 18Jan2006 2006 doi:10.2903/j.efsa.2006.54r
+Fosetyl-aluminium 254-320-2 39148-24-8 single chemical entity Component is identical to the substance Fosetyl-aluminium 254-320-2 39148-24-8 Aluminum;ethoxy-oxido-oxophosphanium Fosetyl-aluminium C6H15AlO9P3+3 CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3] InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3 organometallic compound PubChem canonical SMILES PubChem InChI gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) DNA-polymerase-A-deficient Not reported yes with Negative RMS: France Fosetyl-Al 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl 18Jan2006 2006 doi:10.2903/j.efsa.2006.54r
+Fosetyl-aluminium 254-320-2 39148-24-8 single chemical entity Component is identical to the substance Fosetyl-aluminium 254-320-2 39148-24-8 Aluminum;ethoxy-oxido-oxophosphanium Fosetyl-aluminium C6H15AlO9P3+3 CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3] InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3 organometallic compound PubChem canonical SMILES PubChem InChI gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Saccharomyces cerevisiae (as organism) D7 Not reported yes without Negative RMS: France Fosetyl-Al 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl 18Jan2006 2006 doi:10.2903/j.efsa.2006.54r
+Fosetyl-aluminium 254-320-2 39148-24-8 single chemical entity Component is identical to the substance Fosetyl-aluminium 254-320-2 39148-24-8 Aluminum;ethoxy-oxido-oxophosphanium Fosetyl-aluminium C6H15AlO9P3+3 CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3] InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3 organometallic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: France Fosetyl-Al 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl 18Jan2006 2006 doi:10.2903/j.efsa.2006.54r
+Fosetyl-aluminium 254-320-2 39148-24-8 single chemical entity Component is identical to the substance Fosetyl-aluminium 254-320-2 39148-24-8 Aluminum;ethoxy-oxido-oxophosphanium Fosetyl-aluminium C6H15AlO9P3+3 CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3] InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3 organometallic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: France Fosetyl-Al 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl 18Jan2006 2006 doi:10.2903/j.efsa.2006.54r
+Fosetyl-aluminium 254-320-2 39148-24-8 single chemical entity Component is identical to the substance Fosetyl-aluminium 254-320-2 39148-24-8 Aluminum;ethoxy-oxido-oxophosphanium Fosetyl-aluminium C6H15AlO9P3+3 CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3] InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3 organometallic compound PubChem canonical SMILES PubChem InChI gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) DNA-polymerase-A-proficient Not reported yes with Negative RMS: France Fosetyl-Al 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl 18Jan2006 2006 doi:10.2903/j.efsa.2006.54r
+Fosetyl-aluminium 254-320-2 39148-24-8 single chemical entity Component is identical to the substance Fosetyl-aluminium 254-320-2 39148-24-8 Aluminum;ethoxy-oxido-oxophosphanium Fosetyl-aluminium C6H15AlO9P3+3 CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3] InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3 organometallic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: France Fosetyl-Al 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl 18Jan2006 2006 doi:10.2903/j.efsa.2006.54r
+Fosetyl-aluminium 254-320-2 39148-24-8 single chemical entity Component is identical to the substance Fosetyl-aluminium 254-320-2 39148-24-8 Aluminum;ethoxy-oxido-oxophosphanium Fosetyl-aluminium C6H15AlO9P3+3 CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3] InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3 organometallic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: France Fosetyl-Al 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl 18Jan2006 2006 doi:10.2903/j.efsa.2006.54r
+Potassium phosphonates mixture or formulation Component is identical to the substance Potassium phosphonates tripotassium;phosphite Not in list K3O3P [O-]P([O-])[O-].[K+].[K+].[K+] InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: France Potassium phosphite 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates 18Dec2012 2012 doi:10.2903/j.efsa.2012.2963
+Potassium phosphonates mixture or formulation Component is identical to the substance Potassium phosphonates tripotassium;phosphite Not in list K3O3P [O-]P([O-])[O-].[K+].[K+].[K+] InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) DNA-polymerase-A-deficient Not reported yes without Negative RMS: France Potassium phosphite 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates 18Dec2012 2012 doi:10.2903/j.efsa.2012.2963
+Potassium phosphonates mixture or formulation Component is identical to the substance Potassium phosphonates tripotassium;phosphite Not in list K3O3P [O-]P([O-])[O-].[K+].[K+].[K+] InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: France Potassium phosphite 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates 18Dec2012 2012 doi:10.2903/j.efsa.2012.2963
+Fosetyl-aluminium 254-320-2 39148-24-8 single chemical entity Component is identical to the substance Fosetyl-aluminium 254-320-2 39148-24-8 Aluminum;ethoxy-oxido-oxophosphanium Fosetyl-aluminium C6H15AlO9P3+3 CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3] InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3 organometallic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: France Fosetyl-Al 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl 18Jan2006 2006 doi:10.2903/j.efsa.2006.54r
+Fosetyl-aluminium 254-320-2 39148-24-8 single chemical entity Component is identical to the substance Fosetyl-aluminium 254-320-2 39148-24-8 Aluminum;ethoxy-oxido-oxophosphanium Fosetyl-aluminium C6H15AlO9P3+3 CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3] InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3 organometallic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: France Fosetyl-Al 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl 18Jan2006 2006 doi:10.2903/j.efsa.2006.54r
+Fosetyl-aluminium 254-320-2 39148-24-8 single chemical entity Component is identical to the substance Fosetyl-aluminium 254-320-2 39148-24-8 Aluminum;ethoxy-oxido-oxophosphanium Fosetyl-aluminium C6H15AlO9P3+3 CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3] InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3 organometallic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: France Fosetyl-Al 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl 18Jan2006 2006 doi:10.2903/j.efsa.2006.54r
+Fosetyl-aluminium 254-320-2 39148-24-8 single chemical entity Component is identical to the substance Fosetyl-aluminium 254-320-2 39148-24-8 Aluminum;ethoxy-oxido-oxophosphanium Fosetyl-aluminium C6H15AlO9P3+3 CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3] InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3 organometallic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: France Fosetyl-Al 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl 18Jan2006 2006 doi:10.2903/j.efsa.2006.54r
+Fosetyl-aluminium 254-320-2 39148-24-8 single chemical entity Component is identical to the substance Fosetyl-aluminium 254-320-2 39148-24-8 Aluminum;ethoxy-oxido-oxophosphanium Fosetyl-aluminium C6H15AlO9P3+3 CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3] InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3 organometallic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: France Fosetyl-Al 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl 18Jan2006 2006 doi:10.2903/j.efsa.2006.54r
+Fosetyl-aluminium 254-320-2 39148-24-8 single chemical entity Component is identical to the substance Fosetyl-aluminium 254-320-2 39148-24-8 Aluminum;ethoxy-oxido-oxophosphanium Fosetyl-aluminium C6H15AlO9P3+3 CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3] InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3 organometallic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: France Fosetyl-Al 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl 18Jan2006 2006 doi:10.2903/j.efsa.2006.54r
+Fosetyl-aluminium 254-320-2 39148-24-8 single chemical entity Component is identical to the substance Fosetyl-aluminium 254-320-2 39148-24-8 Aluminum;ethoxy-oxido-oxophosphanium Fosetyl-aluminium C6H15AlO9P3+3 CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3] InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3 organometallic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: France Fosetyl-Al 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl 18Jan2006 2006 doi:10.2903/j.efsa.2006.54r
+Fosetyl-aluminium 254-320-2 39148-24-8 single chemical entity Component is identical to the substance Fosetyl-aluminium 254-320-2 39148-24-8 Aluminum;ethoxy-oxido-oxophosphanium Fosetyl-aluminium C6H15AlO9P3+3 CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3] InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3 organometallic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: France Fosetyl-Al 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl 18Jan2006 2006 doi:10.2903/j.efsa.2006.54r
+Fosetyl-aluminium 254-320-2 39148-24-8 single chemical entity Component is identical to the substance Fosetyl-aluminium 254-320-2 39148-24-8 Aluminum;ethoxy-oxido-oxophosphanium Fosetyl-aluminium C6H15AlO9P3+3 CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3] InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3 organometallic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: France Fosetyl-Al 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl 18Jan2006 2006 doi:10.2903/j.efsa.2006.54r
+Fosetyl-aluminium 254-320-2 39148-24-8 single chemical entity Component is identical to the substance Fosetyl-aluminium 254-320-2 39148-24-8 Aluminum;ethoxy-oxido-oxophosphanium Fosetyl-aluminium C6H15AlO9P3+3 CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3] InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3 organometallic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: France Fosetyl-Al 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl 18Jan2006 2006 doi:10.2903/j.efsa.2006.54r
+Fosetyl-aluminium 254-320-2 39148-24-8 single chemical entity Component is identical to the substance Fosetyl-aluminium 254-320-2 39148-24-8 Aluminum;ethoxy-oxido-oxophosphanium Fosetyl-aluminium C6H15AlO9P3+3 CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3] InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3 organometallic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: France Fosetyl-Al 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl 18Jan2006 2006 doi:10.2903/j.efsa.2006.54r
+Fosetyl-aluminium 254-320-2 39148-24-8 single chemical entity Component is identical to the substance Fosetyl-aluminium 254-320-2 39148-24-8 Aluminum;ethoxy-oxido-oxophosphanium Fosetyl-aluminium C6H15AlO9P3+3 CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3] InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3 organometallic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: France Fosetyl-Al 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl 18Jan2006 2006 doi:10.2903/j.efsa.2006.54r
+Fosetyl-aluminium 254-320-2 39148-24-8 single chemical entity Component is identical to the substance Fosetyl-aluminium 254-320-2 39148-24-8 Aluminum;ethoxy-oxido-oxophosphanium Fosetyl-aluminium C6H15AlO9P3+3 CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3] InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3 organometallic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: France Fosetyl-Al 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl 18Jan2006 2006 doi:10.2903/j.efsa.2006.54r
+Fosetyl-aluminium 254-320-2 39148-24-8 single chemical entity Component is identical to the substance Fosetyl-aluminium 254-320-2 39148-24-8 Aluminum;ethoxy-oxido-oxophosphanium Fosetyl-aluminium C6H15AlO9P3+3 CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3] InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3 organometallic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: France Fosetyl-Al 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl 18Jan2006 2006 doi:10.2903/j.efsa.2006.54r
+Fosetyl-aluminium 254-320-2 39148-24-8 single chemical entity Component is identical to the substance Fosetyl-aluminium 254-320-2 39148-24-8 Aluminum;ethoxy-oxido-oxophosphanium Fosetyl-aluminium C6H15AlO9P3+3 CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3] InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3 organometallic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Swiss 10 Male oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: France Fosetyl-Al 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl 18Jan2006 2006 doi:10.2903/j.efsa.2006.54r
+Fosetyl-aluminium 254-320-2 39148-24-8 single chemical entity Component is a metabolite of the substance Phosphorous acid 233-663-1 10294-56-1 Phosphorous acid Not in list H3O3P OP(O)O InChI=1S/H3O3P/c1-4(2)3/h1-3H inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Swiss 5 Male oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: France Fosetyl-Al 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl 18Jan2006 2006 doi:10.2903/j.efsa.2006.54r
+Potassium phosphonates mixture or formulation Component is identical to the substance Potassium phosphonates tripotassium;phosphite Not in list K3O3P [O-]P([O-])[O-].[K+].[K+].[K+] InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Swiss 10 Male oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: France Potassium phosphite 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates 18Dec2012 2012 doi:10.2903/j.efsa.2012.2963
+Fosetyl-aluminium 254-320-2 39148-24-8 single chemical entity Component is identical to the substance Fosetyl-aluminium 254-320-2 39148-24-8 Aluminum;ethoxy-oxido-oxophosphanium Fosetyl-aluminium C6H15AlO9P3+3 CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3] InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3 organometallic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes not applicable Negative indirect evidence-systemic toxicity RMS: France Fosetyl-Al 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl 18Jan2006 2006 doi:10.2903/j.efsa.2006.54r
+Fosetyl-aluminium 254-320-2 39148-24-8 single chemical entity Component is identical to the substance Fosetyl-aluminium 254-320-2 39148-24-8 Aluminum;ethoxy-oxido-oxophosphanium Fosetyl-aluminium C6H15AlO9P3+3 CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3] InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3 organometallic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 48.0000000000 h yes not applicable Negative indirect evidence-systemic toxicity RMS: France Fosetyl-Al 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl 18Jan2006 2006 doi:10.2903/j.efsa.2006.54r
+Fosetyl-aluminium 254-320-2 39148-24-8 single chemical entity Component is identical to the substance Fosetyl-aluminium 254-320-2 39148-24-8 Aluminum;ethoxy-oxido-oxophosphanium Fosetyl-aluminium C6H15AlO9P3+3 CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3] InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3 organometallic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 72.0000000000 h yes not applicable Negative indirect evidence-systemic toxicity RMS: France Fosetyl-Al 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl 18Jan2006 2006 doi:10.2903/j.efsa.2006.54r
+Fosetyl-aluminium 254-320-2 39148-24-8 single chemical entity Component is identical to the substance Fosetyl-aluminium 254-320-2 39148-24-8 Aluminum;ethoxy-oxido-oxophosphanium Fosetyl-aluminium C6H15AlO9P3+3 CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3] InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3 organometallic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable House mouse (as animal) CD-1 Male oral: unspecified no data not applicable Negative no evidence RMS: France Fosetyl-Al 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl 18Jan2006 2006 doi:10.2903/j.efsa.2006.54r
+Potassium phosphonates mixture or formulation Component is identical to the substance Potassium phosphonates tripotassium;phosphite Not in list K3O3P [O-]P([O-])[O-].[K+].[K+].[K+] InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable House mouse (as animal) CD-1 Male oral: unspecified no data not applicable Negative no evidence RMS: France Potassium phosphite 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates 18Dec2012 2012 doi:10.2903/j.efsa.2012.2963
+Potassium phosphonates mixture or formulation Component is identical to the substance Potassium phosphonates tripotassium;phosphite Not in list K3O3P [O-]P([O-])[O-].[K+].[K+].[K+] InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) K12 Not reported no data without Negative RMS: France Potassium phosphite 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates 18Dec2012 2012 doi:10.2903/j.efsa.2012.2963
+Potassium phosphonates mixture or formulation Component is identical to the substance Potassium phosphonates tripotassium;phosphite Not in list K3O3P [O-]P([O-])[O-].[K+].[K+].[K+] InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) K12 Not reported no data with Negative RMS: France Potassium phosphite 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates 18Dec2012 2012 doi:10.2903/j.efsa.2012.2963
+Fosetyl-aluminium 254-320-2 39148-24-8 single chemical entity Component is a metabolite of the substance Phosphorous acid 233-663-1 10294-56-1 Phosphorous acid Not in list H3O3P OP(O)O InChI=1S/H3O3P/c1-4(2)3/h1-3H inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) K12 Not reported no data with Negative RMS: France Fosetyl-Al 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl 18Jan2006 2006 doi:10.2903/j.efsa.2006.54r
+Fosetyl-aluminium 254-320-2 39148-24-8 single chemical entity Component is a metabolite of the substance Phosphorous acid 233-663-1 10294-56-1 Phosphorous acid Not in list H3O3P OP(O)O InChI=1S/H3O3P/c1-4(2)3/h1-3H inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) K12 Not reported no data without Negative RMS: France Fosetyl-Al 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl 18Jan2006 2006 doi:10.2903/j.efsa.2006.54r
+Fosetyl-aluminium 254-320-2 39148-24-8 single chemical entity Component is a metabolite of the substance Phosphorous acid 233-663-1 10294-56-1 Phosphorous acid Not in list H3O3P OP(O)O InChI=1S/H3O3P/c1-4(2)3/h1-3H inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: France Fosetyl-Al 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl 18Jan2006 2006 doi:10.2903/j.efsa.2006.54r
+Fosetyl-aluminium 254-320-2 39148-24-8 single chemical entity Component is a metabolite of the substance Phosphorous acid 233-663-1 10294-56-1 Phosphorous acid Not in list H3O3P OP(O)O InChI=1S/H3O3P/c1-4(2)3/h1-3H inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: France Fosetyl-Al 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl 18Jan2006 2006 doi:10.2903/j.efsa.2006.54r
+Fosetyl-aluminium 254-320-2 39148-24-8 single chemical entity Component is a metabolite of the substance Phosphorous acid 233-663-1 10294-56-1 Phosphorous acid Not in list H3O3P OP(O)O InChI=1S/H3O3P/c1-4(2)3/h1-3H inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: France Fosetyl-Al 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl 18Jan2006 2006 doi:10.2903/j.efsa.2006.54r
+Fosetyl-aluminium 254-320-2 39148-24-8 single chemical entity Component is a metabolite of the substance Phosphorous acid 233-663-1 10294-56-1 Phosphorous acid Not in list H3O3P OP(O)O InChI=1S/H3O3P/c1-4(2)3/h1-3H inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: France Fosetyl-Al 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl 18Jan2006 2006 doi:10.2903/j.efsa.2006.54r
+Fosetyl-aluminium 254-320-2 39148-24-8 single chemical entity Component is a metabolite of the substance Phosphorous acid 233-663-1 10294-56-1 Phosphorous acid Not in list H3O3P OP(O)O InChI=1S/H3O3P/c1-4(2)3/h1-3H inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: France Fosetyl-Al 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl 18Jan2006 2006 doi:10.2903/j.efsa.2006.54r
+Fosetyl-aluminium 254-320-2 39148-24-8 single chemical entity Component is a metabolite of the substance Phosphorous acid 233-663-1 10294-56-1 Phosphorous acid Not in list H3O3P OP(O)O InChI=1S/H3O3P/c1-4(2)3/h1-3H inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: France Fosetyl-Al 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl 18Jan2006 2006 doi:10.2903/j.efsa.2006.54r
+Fosetyl-aluminium 254-320-2 39148-24-8 single chemical entity Component is a metabolite of the substance Phosphorous acid 233-663-1 10294-56-1 Phosphorous acid Not in list H3O3P OP(O)O InChI=1S/H3O3P/c1-4(2)3/h1-3H inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: France Fosetyl-Al 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl 18Jan2006 2006 doi:10.2903/j.efsa.2006.54r
+Fosetyl-aluminium 254-320-2 39148-24-8 single chemical entity Component is a metabolite of the substance Phosphorous acid 233-663-1 10294-56-1 Phosphorous acid Not in list H3O3P OP(O)O InChI=1S/H3O3P/c1-4(2)3/h1-3H inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: France Fosetyl-Al 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl 18Jan2006 2006 doi:10.2903/j.efsa.2006.54r
+Fosetyl-aluminium 254-320-2 39148-24-8 single chemical entity Component is a metabolite of the substance Phosphorous acid 233-663-1 10294-56-1 Phosphorous acid Not in list H3O3P OP(O)O InChI=1S/H3O3P/c1-4(2)3/h1-3H inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: France Fosetyl-Al 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl 18Jan2006 2006 doi:10.2903/j.efsa.2006.54r
+Fosetyl-aluminium 254-320-2 39148-24-8 single chemical entity Component is a metabolite of the substance Phosphorous acid 233-663-1 10294-56-1 Phosphorous acid Not in list H3O3P OP(O)O InChI=1S/H3O3P/c1-4(2)3/h1-3H inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: France Fosetyl-Al 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl 18Jan2006 2006 doi:10.2903/j.efsa.2006.54r
+Fosetyl-aluminium 254-320-2 39148-24-8 single chemical entity Component is a metabolite of the substance Phosphorous acid 233-663-1 10294-56-1 Phosphorous acid Not in list H3O3P OP(O)O InChI=1S/H3O3P/c1-4(2)3/h1-3H inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: France Fosetyl-Al 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl 18Jan2006 2006 doi:10.2903/j.efsa.2006.54r
+Fosetyl-aluminium 254-320-2 39148-24-8 single chemical entity Component is a metabolite of the substance Phosphorous acid 233-663-1 10294-56-1 Phosphorous acid Not in list H3O3P OP(O)O InChI=1S/H3O3P/c1-4(2)3/h1-3H inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: France Fosetyl-Al 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl 18Jan2006 2006 doi:10.2903/j.efsa.2006.54r
+Fosetyl-aluminium 254-320-2 39148-24-8 single chemical entity Component is a metabolite of the substance Phosphorous acid 233-663-1 10294-56-1 Phosphorous acid Not in list H3O3P OP(O)O InChI=1S/H3O3P/c1-4(2)3/h1-3H inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: France Fosetyl-Al 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl 18Jan2006 2006 doi:10.2903/j.efsa.2006.54r
+Fosetyl-aluminium 254-320-2 39148-24-8 single chemical entity Component is a metabolite of the substance Phosphorous acid 233-663-1 10294-56-1 Phosphorous acid Not in list H3O3P OP(O)O InChI=1S/H3O3P/c1-4(2)3/h1-3H inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: France Fosetyl-Al 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl 18Jan2006 2006 doi:10.2903/j.efsa.2006.54r
+Fosetyl-aluminium 254-320-2 39148-24-8 single chemical entity Component is a metabolite of the substance Phosphorous acid 233-663-1 10294-56-1 Phosphorous acid Not in list H3O3P OP(O)O InChI=1S/H3O3P/c1-4(2)3/h1-3H inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: France Fosetyl-Al 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl 18Jan2006 2006 doi:10.2903/j.efsa.2006.54r
+Fosetyl-aluminium 254-320-2 39148-24-8 single chemical entity Component is a metabolite of the substance Phosphorous acid 233-663-1 10294-56-1 Phosphorous acid Not in list H3O3P OP(O)O InChI=1S/H3O3P/c1-4(2)3/h1-3H inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: France Fosetyl-Al 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl 18Jan2006 2006 doi:10.2903/j.efsa.2006.54r
+Fosetyl-aluminium 254-320-2 39148-24-8 single chemical entity Component is a metabolite of the substance Phosphorous acid 233-663-1 10294-56-1 Phosphorous acid Not in list H3O3P OP(O)O InChI=1S/H3O3P/c1-4(2)3/h1-3H inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: France Fosetyl-Al 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl 18Jan2006 2006 doi:10.2903/j.efsa.2006.54r
+Fosetyl-aluminium 254-320-2 39148-24-8 single chemical entity Component is a metabolite of the substance Phosphorous acid 233-663-1 10294-56-1 Phosphorous acid Not in list H3O3P OP(O)O InChI=1S/H3O3P/c1-4(2)3/h1-3H inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: France Fosetyl-Al 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl 18Jan2006 2006 doi:10.2903/j.efsa.2006.54r
+Potassium phosphonates mixture or formulation Component is identical to the substance Potassium phosphonates tripotassium;phosphite Not in list K3O3P [O-]P([O-])[O-].[K+].[K+].[K+] InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Potassium phosphite 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates 18Dec2012 2012 doi:10.2903/j.efsa.2012.2963
+Potassium phosphonates mixture or formulation Component is identical to the substance Potassium phosphonates tripotassium;phosphite Not in list K3O3P [O-]P([O-])[O-].[K+].[K+].[K+] InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: France Potassium phosphite 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates 18Dec2012 2012 doi:10.2903/j.efsa.2012.2963
+Potassium phosphonates mixture or formulation Component is identical to the substance Potassium phosphonates tripotassium;phosphite Not in list K3O3P [O-]P([O-])[O-].[K+].[K+].[K+] InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: France Potassium phosphite 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates 18Dec2012 2012 doi:10.2903/j.efsa.2012.2963
+Potassium phosphonates mixture or formulation Component is identical to the substance Potassium phosphonates tripotassium;phosphite Not in list K3O3P [O-]P([O-])[O-].[K+].[K+].[K+] InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Potassium phosphite 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates 18Dec2012 2012 doi:10.2903/j.efsa.2012.2963
+Potassium phosphonates mixture or formulation Component is identical to the substance Potassium phosphonates tripotassium;phosphite Not in list K3O3P [O-]P([O-])[O-].[K+].[K+].[K+] InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Potassium phosphite 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates 18Dec2012 2012 doi:10.2903/j.efsa.2012.2963
+Potassium phosphonates mixture or formulation Component is identical to the substance Potassium phosphonates tripotassium;phosphite Not in list K3O3P [O-]P([O-])[O-].[K+].[K+].[K+] InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Potassium phosphite 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates 18Dec2012 2012 doi:10.2903/j.efsa.2012.2963
+Potassium phosphonates mixture or formulation Component is identical to the substance Potassium phosphonates tripotassium;phosphite Not in list K3O3P [O-]P([O-])[O-].[K+].[K+].[K+] InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Potassium phosphite 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates 18Dec2012 2012 doi:10.2903/j.efsa.2012.2963
+Potassium phosphonates mixture or formulation Component is identical to the substance Potassium phosphonates tripotassium;phosphite Not in list K3O3P [O-]P([O-])[O-].[K+].[K+].[K+] InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Potassium phosphite 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates 18Dec2012 2012 doi:10.2903/j.efsa.2012.2963
+Potassium phosphonates mixture or formulation Component is identical to the substance Potassium phosphonates tripotassium;phosphite Not in list K3O3P [O-]P([O-])[O-].[K+].[K+].[K+] InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Potassium phosphite 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates 18Dec2012 2012 doi:10.2903/j.efsa.2012.2963
+Potassium phosphonates mixture or formulation Component is identical to the substance Potassium phosphonates tripotassium;phosphite Not in list K3O3P [O-]P([O-])[O-].[K+].[K+].[K+] InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Potassium phosphite 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates 18Dec2012 2012 doi:10.2903/j.efsa.2012.2963
+Potassium phosphonates mixture or formulation Component is identical to the substance Potassium phosphonates tripotassium;phosphite Not in list K3O3P [O-]P([O-])[O-].[K+].[K+].[K+] InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) ICR 5 Male intraveneous 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: France Potassium phosphite (Addendum 1) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates 18Dec2012 2012 doi:10.2903/j.efsa.2012.2963
+Potassium phosphonates mixture or formulation Component is identical to the substance Potassium phosphonates tripotassium;phosphite Not in list K3O3P [O-]P([O-])[O-].[K+].[K+].[K+] InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) ICR 5 Male intraveneous 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: France Potassium phosphite (Addendum 1) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates 18Dec2012 2012 doi:10.2903/j.efsa.2012.2963
+Oxydemeton-methyl 206-110-7 301-12-2 single chemical entity Component is identical to the substance Oxydemeton-methyl 206-110-7 301-12-2 1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane Oxydemeton-methyl C6H15O4PS2 CCS(=O)CCSP(=O)(OC)OC InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Oxydemeton-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl 28Jul2006 2006 doi:10.2903/j.efsa.2006.86r
+Oxydemeton-methyl 206-110-7 301-12-2 single chemical entity Component is identical to the substance Oxydemeton-methyl 206-110-7 301-12-2 1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane Oxydemeton-methyl C6H15O4PS2 CCS(=O)CCSP(=O)(OC)OC InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Positive RMS: France Oxydemeton-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl 28Jul2006 2006 doi:10.2903/j.efsa.2006.86r
+Oxydemeton-methyl 206-110-7 301-12-2 single chemical entity Component is identical to the substance Oxydemeton-methyl 206-110-7 301-12-2 1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane Oxydemeton-methyl C6H15O4PS2 CCS(=O)CCSP(=O)(OC)OC InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Positive RMS: France Oxydemeton-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl 28Jul2006 2006 doi:10.2903/j.efsa.2006.86r
+Oxydemeton-methyl 206-110-7 301-12-2 single chemical entity Component is identical to the substance Oxydemeton-methyl 206-110-7 301-12-2 1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane Oxydemeton-methyl C6H15O4PS2 CCS(=O)CCSP(=O)(OC)OC InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Positive RMS: France Oxydemeton-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl 28Jul2006 2006 doi:10.2903/j.efsa.2006.86r
+Oxydemeton-methyl 206-110-7 301-12-2 single chemical entity Component is identical to the substance Oxydemeton-methyl 206-110-7 301-12-2 1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane Oxydemeton-methyl C6H15O4PS2 CCS(=O)CCSP(=O)(OC)OC InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Oxydemeton-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl 28Jul2006 2006 doi:10.2903/j.efsa.2006.86r
+Oxydemeton-methyl 206-110-7 301-12-2 single chemical entity Component is identical to the substance Oxydemeton-methyl 206-110-7 301-12-2 1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane Oxydemeton-methyl C6H15O4PS2 CCS(=O)CCSP(=O)(OC)OC InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Oxydemeton-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl 28Jul2006 2006 doi:10.2903/j.efsa.2006.86r
+Oxydemeton-methyl 206-110-7 301-12-2 single chemical entity Component is identical to the substance Oxydemeton-methyl 206-110-7 301-12-2 1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane Oxydemeton-methyl C6H15O4PS2 CCS(=O)CCSP(=O)(OC)OC InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Positive RMS: France Oxydemeton-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl 28Jul2006 2006 doi:10.2903/j.efsa.2006.86r
+Oxydemeton-methyl 206-110-7 301-12-2 single chemical entity Component is identical to the substance Oxydemeton-methyl 206-110-7 301-12-2 1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane Oxydemeton-methyl C6H15O4PS2 CCS(=O)CCSP(=O)(OC)OC InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Oxydemeton-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl 28Jul2006 2006 doi:10.2903/j.efsa.2006.86r
+Oxydemeton-methyl 206-110-7 301-12-2 single chemical entity Component is identical to the substance Oxydemeton-methyl 206-110-7 301-12-2 1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane Oxydemeton-methyl C6H15O4PS2 CCS(=O)CCSP(=O)(OC)OC InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation yeast cytogenetic assay in vitro Equivalent or similar to OECD Guideline 480 (Genetic Toxicology: Saccharomyces cerevisiae, Gene Mutation Assay) No data Acceptable Saccharomyces cerevisiae (as organism) S138 Not reported yes, concurrent vehicle without Negative RMS: France Oxydemeton-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl 28Jul2006 2006 doi:10.2903/j.efsa.2006.86r
+Oxydemeton-methyl 206-110-7 301-12-2 single chemical entity Component is identical to the substance Oxydemeton-methyl 206-110-7 301-12-2 1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane Oxydemeton-methyl C6H15O4PS2 CCS(=O)CCSP(=O)(OC)OC InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation yeast cytogenetic assay in vitro Equivalent or similar to OECD Guideline 480 (Genetic Toxicology: Saccharomyces cerevisiae, Gene Mutation Assay) No data Acceptable Saccharomyces cerevisiae (as organism) S138 Not reported yes, concurrent vehicle with Negative RMS: France Oxydemeton-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl 28Jul2006 2006 doi:10.2903/j.efsa.2006.86r
+Oxydemeton-methyl 206-110-7 301-12-2 single chemical entity Component is identical to the substance Oxydemeton-methyl 206-110-7 301-12-2 1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane Oxydemeton-methyl C6H15O4PS2 CCS(=O)CCSP(=O)(OC)OC InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes, concurrent vehicle without Negative RMS: France Oxydemeton-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl 28Jul2006 2006 doi:10.2903/j.efsa.2006.86r
+Oxydemeton-methyl 206-110-7 301-12-2 single chemical entity Component is identical to the substance Oxydemeton-methyl 206-110-7 301-12-2 1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane Oxydemeton-methyl C6H15O4PS2 CCS(=O)CCSP(=O)(OC)OC InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation yeast cytogenetic assay in vitro Equivalent or similar to OECD Guideline 480 (Genetic Toxicology: Saccharomyces cerevisiae, Gene Mutation Assay) No data Acceptable Saccharomyces cerevisiae (as organism) S211α Not reported yes, concurrent vehicle without Negative RMS: France Oxydemeton-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl 28Jul2006 2006 doi:10.2903/j.efsa.2006.86r
+Oxydemeton-methyl 206-110-7 301-12-2 single chemical entity Component is identical to the substance Oxydemeton-methyl 206-110-7 301-12-2 1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane Oxydemeton-methyl C6H15O4PS2 CCS(=O)CCSP(=O)(OC)OC InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes, concurrent vehicle without Negative RMS: France Oxydemeton-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl 28Jul2006 2006 doi:10.2903/j.efsa.2006.86r
+Oxydemeton-methyl 206-110-7 301-12-2 single chemical entity Component is identical to the substance Oxydemeton-methyl 206-110-7 301-12-2 1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane Oxydemeton-methyl C6H15O4PS2 CCS(=O)CCSP(=O)(OC)OC InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes, concurrent vehicle with Negative RMS: France Oxydemeton-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl 28Jul2006 2006 doi:10.2903/j.efsa.2006.86r
+Oxydemeton-methyl 206-110-7 301-12-2 single chemical entity Component is identical to the substance Oxydemeton-methyl 206-110-7 301-12-2 1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane Oxydemeton-methyl C6H15O4PS2 CCS(=O)CCSP(=O)(OC)OC InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes, concurrent vehicle with Negative RMS: France Oxydemeton-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl 28Jul2006 2006 doi:10.2903/j.efsa.2006.86r
+Oxydemeton-methyl 206-110-7 301-12-2 single chemical entity Component is identical to the substance Oxydemeton-methyl 206-110-7 301-12-2 1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane Oxydemeton-methyl C6H15O4PS2 CCS(=O)CCSP(=O)(OC)OC InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation yeast cytogenetic assay in vitro Equivalent or similar to OECD Guideline 480 (Genetic Toxicology: Saccharomyces cerevisiae, Gene Mutation Assay) No data Acceptable Saccharomyces cerevisiae (as organism) S211α Not reported yes, concurrent vehicle with Negative RMS: France Oxydemeton-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl 28Jul2006 2006 doi:10.2903/j.efsa.2006.86r
+Oxydemeton-methyl 206-110-7 301-12-2 single chemical entity Component is identical to the substance Oxydemeton-methyl 206-110-7 301-12-2 1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane Oxydemeton-methyl C6H15O4PS2 CCS(=O)CCSP(=O)(OC)OC InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vitro No guideline available Not reported Not applicable Acceptable Rat (as animal) Testis cell Not reported yes without Positive RMS: France Oxydemeton-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl 28Jul2006 2006 doi:10.2903/j.efsa.2006.86r
+Oxydemeton-methyl 206-110-7 301-12-2 single chemical entity Component is identical to the substance Oxydemeton-methyl 206-110-7 301-12-2 1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane Oxydemeton-methyl C6H15O4PS2 CCS(=O)CCSP(=O)(OC)OC InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vitro No guideline available Not reported Not applicable Acceptable Hamster (as animal) CHO Not reported yes with Positive RMS: France Oxydemeton-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl 28Jul2006 2006 doi:10.2903/j.efsa.2006.86r
+Oxydemeton-methyl 206-110-7 301-12-2 single chemical entity Component is identical to the substance Oxydemeton-methyl 206-110-7 301-12-2 1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane Oxydemeton-methyl C6H15O4PS2 CCS(=O)CCSP(=O)(OC)OC InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vitro No guideline available Not reported Not applicable Acceptable Hamster (as animal) CHO Not reported yes without Positive RMS: France Oxydemeton-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl 28Jul2006 2006 doi:10.2903/j.efsa.2006.86r
+Oxydemeton-methyl 206-110-7 301-12-2 single chemical entity Component is identical to the substance Oxydemeton-methyl 206-110-7 301-12-2 1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane Oxydemeton-methyl C6H15O4PS2 CCS(=O)CCSP(=O)(OC)OC InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No data Acceptable Hamster (as animal) CHO Not reported yes without Positive RMS: France Oxydemeton-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl 28Jul2006 2006 doi:10.2903/j.efsa.2006.86r
+Oxydemeton-methyl 206-110-7 301-12-2 single chemical entity Component is identical to the substance Oxydemeton-methyl 206-110-7 301-12-2 1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane Oxydemeton-methyl C6H15O4PS2 CCS(=O)CCSP(=O)(OC)OC InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No data Acceptable Hamster (as animal) CHO Not reported yes with Positive RMS: France Oxydemeton-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl 28Jul2006 2006 doi:10.2903/j.efsa.2006.86r
+Oxydemeton-methyl 206-110-7 301-12-2 single chemical entity Component is identical to the substance Oxydemeton-methyl 206-110-7 301-12-2 1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane Oxydemeton-methyl C6H15O4PS2 CCS(=O)CCSP(=O)(OC)OC InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes with Positive RMS: France Oxydemeton-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl 28Jul2006 2006 doi:10.2903/j.efsa.2006.86r
+Oxydemeton-methyl 206-110-7 301-12-2 single chemical entity Component is identical to the substance Oxydemeton-methyl 206-110-7 301-12-2 1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane Oxydemeton-methyl C6H15O4PS2 CCS(=O)CCSP(=O)(OC)OC InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes without Positive RMS: France Oxydemeton-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl 28Jul2006 2006 doi:10.2903/j.efsa.2006.86r
+Oxydemeton-methyl 206-110-7 301-12-2 single chemical entity Component is identical to the substance Oxydemeton-methyl 206-110-7 301-12-2 1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane Oxydemeton-methyl C6H15O4PS2 CCS(=O)CCSP(=O)(OC)OC InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Positive no information RMS: France Oxydemeton-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl 28Jul2006 2006 doi:10.2903/j.efsa.2006.86r
+Oxydemeton-methyl 206-110-7 301-12-2 single chemical entity Component is identical to the substance Oxydemeton-methyl 206-110-7 301-12-2 1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane Oxydemeton-methyl C6H15O4PS2 CCS(=O)CCSP(=O)(OC)OC InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Positive no information RMS: France Oxydemeton-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl 28Jul2006 2006 doi:10.2903/j.efsa.2006.86r
+Oxydemeton-methyl 206-110-7 301-12-2 single chemical entity Component is identical to the substance Oxydemeton-methyl 206-110-7 301-12-2 1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane Oxydemeton-methyl C6H15O4PS2 CCS(=O)CCSP(=O)(OC)OC InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Rat (as animal) hepatocytes Not reported yes without Inconclusive RMS: France Oxydemeton-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl 28Jul2006 2006 doi:10.2903/j.efsa.2006.86r
+Oxydemeton-methyl 206-110-7 301-12-2 single chemical entity Component is identical to the substance Oxydemeton-methyl 206-110-7 301-12-2 1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane Oxydemeton-methyl C6H15O4PS2 CCS(=O)CCSP(=O)(OC)OC InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No data Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: France Oxydemeton-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl 28Jul2006 2006 doi:10.2903/j.efsa.2006.86r
+Oxydemeton-methyl 206-110-7 301-12-2 single chemical entity Component is identical to the substance Oxydemeton-methyl 206-110-7 301-12-2 1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane Oxydemeton-methyl C6H15O4PS2 CCS(=O)CCSP(=O)(OC)OC InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Positive RMS: France Oxydemeton-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl 28Jul2006 2006 doi:10.2903/j.efsa.2006.86r
+Oxydemeton-methyl 206-110-7 301-12-2 single chemical entity Component is identical to the substance Oxydemeton-methyl 206-110-7 301-12-2 1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane Oxydemeton-methyl C6H15O4PS2 CCS(=O)CCSP(=O)(OC)OC InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Positive RMS: France Oxydemeton-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl 28Jul2006 2006 doi:10.2903/j.efsa.2006.86r
+Oxydemeton-methyl 206-110-7 301-12-2 single chemical entity Component is identical to the substance Oxydemeton-methyl 206-110-7 301-12-2 1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane Oxydemeton-methyl C6H15O4PS2 CCS(=O)CCSP(=O)(OC)OC InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vivo No guideline available Not reported Not applicable Acceptable Hamster (as animal) Chinese 10 Male/Female intraperitoneal 24.0000000000 h yes not applicable Negative RMS: France Oxydemeton-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl 28Jul2006 2006 doi:10.2903/j.efsa.2006.86r
+Oxydemeton-methyl 206-110-7 301-12-2 single chemical entity Component is identical to the substance Oxydemeton-methyl 206-110-7 301-12-2 1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane Oxydemeton-methyl C6H15O4PS2 CCS(=O)CCSP(=O)(OC)OC InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No data Acceptable Hamster (as animal) Chinese 10 Male/Female oral: unspecified 24.0000000000 h yes not applicable Negative RMS: France Oxydemeton-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl 28Jul2006 2006 doi:10.2903/j.efsa.2006.86r
+Oxydemeton-methyl 206-110-7 301-12-2 single chemical entity Component is identical to the substance Oxydemeton-methyl 206-110-7 301-12-2 1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane Oxydemeton-methyl C6H15O4PS2 CCS(=O)CCSP(=O)(OC)OC InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No data Acceptable Hamster (as animal) Chinese 10 Male/Female oral: unspecified 48.0000000000 h yes not applicable Negative RMS: France Oxydemeton-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl 28Jul2006 2006 doi:10.2903/j.efsa.2006.86r
+Oxydemeton-methyl 206-110-7 301-12-2 single chemical entity Component is identical to the substance Oxydemeton-methyl 206-110-7 301-12-2 1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane Oxydemeton-methyl C6H15O4PS2 CCS(=O)CCSP(=O)(OC)OC InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No data Acceptable Hamster (as animal) Chinese 10 Male/Female oral: unspecified 6.0000000000 h yes not applicable Negative RMS: France Oxydemeton-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl 28Jul2006 2006 doi:10.2903/j.efsa.2006.86r
+Oxydemeton-methyl 206-110-7 301-12-2 single chemical entity Component is identical to the substance Oxydemeton-methyl 206-110-7 301-12-2 1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane Oxydemeton-methyl C6H15O4PS2 CCS(=O)CCSP(=O)(OC)OC InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Not reported 10 Male/Female oral: unspecified 6.0000000000 h yes not applicable Negative no evidence RMS: France Oxydemeton-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl 28Jul2006 2006 doi:10.2903/j.efsa.2006.86r
+Oxydemeton-methyl 206-110-7 301-12-2 single chemical entity Component is identical to the substance Oxydemeton-methyl 206-110-7 301-12-2 1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane Oxydemeton-methyl C6H15O4PS2 CCS(=O)CCSP(=O)(OC)OC InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Not reported 10 Male/Female intraperitoneal 6.0000000000 h yes not applicable Negative no evidence RMS: France Oxydemeton-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl 28Jul2006 2006 doi:10.2903/j.efsa.2006.86r
+Oxydemeton-methyl 206-110-7 301-12-2 single chemical entity Component is identical to the substance Oxydemeton-methyl 206-110-7 301-12-2 1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane Oxydemeton-methyl C6H15O4PS2 CCS(=O)CCSP(=O)(OC)OC InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mouse spot test in vivo Equivalent or similar to OECD Guideline 484 (Genetic Toxicology: Mouse Spot Test) No data Acceptable House mouse (as animal) C57BL Male/Female oral: unspecified yes not applicable Positive RMS: France Oxydemeton-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl 28Jul2006 2006 doi:10.2903/j.efsa.2006.86r
+Oxydemeton-methyl 206-110-7 301-12-2 single chemical entity Component is identical to the substance Oxydemeton-methyl 206-110-7 301-12-2 1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane Oxydemeton-methyl C6H15O4PS2 CCS(=O)CCSP(=O)(OC)OC InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) No data Acceptable House mouse (as animal) Not reported Male oral: unspecified no data not applicable Negative RMS: France Oxydemeton-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl 28Jul2006 2006 doi:10.2903/j.efsa.2006.86r
+Oxydemeton-methyl 206-110-7 301-12-2 single chemical entity Component is identical to the substance Oxydemeton-methyl 206-110-7 301-12-2 1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane Oxydemeton-methyl C6H15O4PS2 CCS(=O)CCSP(=O)(OC)OC InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) No data Acceptable House mouse (as animal) CD-1 20 Male intraperitoneal yes, concurrent vehicle not applicable Negative RMS: France Oxydemeton-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl 28Jul2006 2006 doi:10.2903/j.efsa.2006.86r
+Oxydemeton-methyl 206-110-7 301-12-2 single chemical entity Component is identical to the substance Oxydemeton-methyl 206-110-7 301-12-2 1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane Oxydemeton-methyl C6H15O4PS2 CCS(=O)CCSP(=O)(OC)OC InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) No data Acceptable House mouse (as animal) CD-1 20 Male intraperitoneal yes, concurrent vehicle not applicable Negative RMS: France Oxydemeton-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl 28Jul2006 2006 doi:10.2903/j.efsa.2006.86r
+Oxydemeton-methyl 206-110-7 301-12-2 single chemical entity Component is identical to the substance Oxydemeton-methyl 206-110-7 301-12-2 1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane Oxydemeton-methyl C6H15O4PS2 CCS(=O)CCSP(=O)(OC)OC InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo Equivalent or similar to OECD Guideline 489 No data Acceptable Rat (as animal) Sprague-Dawley 4 Male oral: gavage 4.0000000000 h yes not applicable Negative RMS: France Oxydemeton-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl 28Jul2006 2006 doi:10.2903/j.efsa.2006.86r
+Oxydemeton-methyl 206-110-7 301-12-2 single chemical entity Component is identical to the substance Oxydemeton-methyl 206-110-7 301-12-2 1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane Oxydemeton-methyl C6H15O4PS2 CCS(=O)CCSP(=O)(OC)OC InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 7 Male oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: France Oxydemeton-methyl (Final Addendum to the DAR) 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl 28Jul2006 2006 doi:10.2903/j.efsa.2006.86r
+Myclobutanil 88671-89-0 single chemical entity Component is identical to the substance Myclobutanil 88671-89-0 2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile Myclobutanil C15H17ClN4 Clc1ccc(cc1)C(CCCC)(Cn2cncn2)C#N InChI=1S/C15H17ClN4/c1-2-3-8-15(9-17,10-20-12-18-11-19-20)13-4-6-14(16)7-5-13/h4-7,11-12H,2-3,8,10H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is identical to the substance Myclobutanil 88671-89-0 2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile Myclobutanil C15H17ClN4 Clc1ccc(cc1)C(CCCC)(Cn2cncn2)C#N InChI=1S/C15H17ClN4/c1-2-3-8-15(9-17,10-20-12-18-11-19-20)13-4-6-14(16)7-5-13/h4-7,11-12H,2-3,8,10H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is identical to the substance Myclobutanil 88671-89-0 2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile Myclobutanil C15H17ClN4 Clc1ccc(cc1)C(CCCC)(Cn2cncn2)C#N InChI=1S/C15H17ClN4/c1-2-3-8-15(9-17,10-20-12-18-11-19-20)13-4-6-14(16)7-5-13/h4-7,11-12H,2-3,8,10H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is identical to the substance Myclobutanil 88671-89-0 2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile Myclobutanil C15H17ClN4 Clc1ccc(cc1)C(CCCC)(Cn2cncn2)C#N InChI=1S/C15H17ClN4/c1-2-3-8-15(9-17,10-20-12-18-11-19-20)13-4-6-14(16)7-5-13/h4-7,11-12H,2-3,8,10H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is identical to the substance Myclobutanil 88671-89-0 2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile Myclobutanil C15H17ClN4 Clc1ccc(cc1)C(CCCC)(Cn2cncn2)C#N InChI=1S/C15H17ClN4/c1-2-3-8-15(9-17,10-20-12-18-11-19-20)13-4-6-14(16)7-5-13/h4-7,11-12H,2-3,8,10H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is identical to the substance Myclobutanil 88671-89-0 2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile Myclobutanil C15H17ClN4 Clc1ccc(cc1)C(CCCC)(Cn2cncn2)C#N InChI=1S/C15H17ClN4/c1-2-3-8-15(9-17,10-20-12-18-11-19-20)13-4-6-14(16)7-5-13/h4-7,11-12H,2-3,8,10H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is identical to the substance Myclobutanil 88671-89-0 2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile Myclobutanil C15H17ClN4 Clc1ccc(cc1)C(CCCC)(Cn2cncn2)C#N InChI=1S/C15H17ClN4/c1-2-3-8-15(9-17,10-20-12-18-11-19-20)13-4-6-14(16)7-5-13/h4-7,11-12H,2-3,8,10H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is identical to the substance Myclobutanil 88671-89-0 2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile Myclobutanil C15H17ClN4 Clc1ccc(cc1)C(CCCC)(Cn2cncn2)C#N InChI=1S/C15H17ClN4/c1-2-3-8-15(9-17,10-20-12-18-11-19-20)13-4-6-14(16)7-5-13/h4-7,11-12H,2-3,8,10H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is identical to the substance Myclobutanil 88671-89-0 2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile Myclobutanil C15H17ClN4 Clc1ccc(cc1)C(CCCC)(Cn2cncn2)C#N InChI=1S/C15H17ClN4/c1-2-3-8-15(9-17,10-20-12-18-11-19-20)13-4-6-14(16)7-5-13/h4-7,11-12H,2-3,8,10H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is identical to the substance Myclobutanil 88671-89-0 2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile Myclobutanil C15H17ClN4 Clc1ccc(cc1)C(CCCC)(Cn2cncn2)C#N InChI=1S/C15H17ClN4/c1-2-3-8-15(9-17,10-20-12-18-11-19-20)13-4-6-14(16)7-5-13/h4-7,11-12H,2-3,8,10H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is identical to the substance Myclobutanil 88671-89-0 2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile Myclobutanil C15H17ClN4 Clc1ccc(cc1)C(CCCC)(Cn2cncn2)C#N InChI=1S/C15H17ClN4/c1-2-3-8-15(9-17,10-20-12-18-11-19-20)13-4-6-14(16)7-5-13/h4-7,11-12H,2-3,8,10H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is identical to the substance Myclobutanil 88671-89-0 2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile Myclobutanil C15H17ClN4 Clc1ccc(cc1)C(CCCC)(Cn2cncn2)C#N InChI=1S/C15H17ClN4/c1-2-3-8-15(9-17,10-20-12-18-11-19-20)13-4-6-14(16)7-5-13/h4-7,11-12H,2-3,8,10H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is identical to the substance Myclobutanil 88671-89-0 2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile Myclobutanil C15H17ClN4 Clc1ccc(cc1)C(CCCC)(Cn2cncn2)C#N InChI=1S/C15H17ClN4/c1-2-3-8-15(9-17,10-20-12-18-11-19-20)13-4-6-14(16)7-5-13/h4-7,11-12H,2-3,8,10H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is identical to the substance Myclobutanil 88671-89-0 2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile Myclobutanil C15H17ClN4 Clc1ccc(cc1)C(CCCC)(Cn2cncn2)C#N InChI=1S/C15H17ClN4/c1-2-3-8-15(9-17,10-20-12-18-11-19-20)13-4-6-14(16)7-5-13/h4-7,11-12H,2-3,8,10H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is identical to the substance Myclobutanil 88671-89-0 2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile Myclobutanil C15H17ClN4 Clc1ccc(cc1)C(CCCC)(Cn2cncn2)C#N InChI=1S/C15H17ClN4/c1-2-3-8-15(9-17,10-20-12-18-11-19-20)13-4-6-14(16)7-5-13/h4-7,11-12H,2-3,8,10H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is identical to the substance Myclobutanil 88671-89-0 2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile Myclobutanil C15H17ClN4 Clc1ccc(cc1)C(CCCC)(Cn2cncn2)C#N InChI=1S/C15H17ClN4/c1-2-3-8-15(9-17,10-20-12-18-11-19-20)13-4-6-14(16)7-5-13/h4-7,11-12H,2-3,8,10H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is identical to the substance Myclobutanil 88671-89-0 2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile Myclobutanil C15H17ClN4 Clc1ccc(cc1)C(CCCC)(Cn2cncn2)C#N InChI=1S/C15H17ClN4/c1-2-3-8-15(9-17,10-20-12-18-11-19-20)13-4-6-14(16)7-5-13/h4-7,11-12H,2-3,8,10H2,1H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is identical to the substance Myclobutanil 88671-89-0 2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile Myclobutanil C15H17ClN4 Clc1ccc(cc1)C(CCCC)(Cn2cncn2)C#N InChI=1S/C15H17ClN4/c1-2-3-8-15(9-17,10-20-12-18-11-19-20)13-4-6-14(16)7-5-13/h4-7,11-12H,2-3,8,10H2,1H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is identical to the substance Myclobutanil 88671-89-0 2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile Myclobutanil C15H17ClN4 Clc1ccc(cc1)C(CCCC)(Cn2cncn2)C#N InChI=1S/C15H17ClN4/c1-2-3-8-15(9-17,10-20-12-18-11-19-20)13-4-6-14(16)7-5-13/h4-7,11-12H,2-3,8,10H2,1H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is identical to the substance Myclobutanil 88671-89-0 2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile Myclobutanil C15H17ClN4 Clc1ccc(cc1)C(CCCC)(Cn2cncn2)C#N InChI=1S/C15H17ClN4/c1-2-3-8-15(9-17,10-20-12-18-11-19-20)13-4-6-14(16)7-5-13/h4-7,11-12H,2-3,8,10H2,1H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is identical to the substance Myclobutanil 88671-89-0 2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile Myclobutanil C15H17ClN4 Clc1ccc(cc1)C(CCCC)(Cn2cncn2)C#N InChI=1S/C15H17ClN4/c1-2-3-8-15(9-17,10-20-12-18-11-19-20)13-4-6-14(16)7-5-13/h4-7,11-12H,2-3,8,10H2,1H3 organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is identical to the substance Myclobutanil 88671-89-0 2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile Myclobutanil C15H17ClN4 Clc1ccc(cc1)C(CCCC)(Cn2cncn2)C#N InChI=1S/C15H17ClN4/c1-2-3-8-15(9-17,10-20-12-18-11-19-20)13-4-6-14(16)7-5-13/h4-7,11-12H,2-3,8,10H2,1H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) CD-1 10 Male oral: gavage 6.0000000000 h no data not applicable Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is identical to the substance Myclobutanil 88671-89-0 2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile Myclobutanil C15H17ClN4 Clc1ccc(cc1)C(CCCC)(Cn2cncn2)C#N InChI=1S/C15H17ClN4/c1-2-3-8-15(9-17,10-20-12-18-11-19-20)13-4-6-14(16)7-5-13/h4-7,11-12H,2-3,8,10H2,1H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) CD-1 30 Male oral: gavage 48.0000000000 h no data not applicable Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is identical to the substance Myclobutanil 88671-89-0 2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile Myclobutanil C15H17ClN4 Clc1ccc(cc1)C(CCCC)(Cn2cncn2)C#N InChI=1S/C15H17ClN4/c1-2-3-8-15(9-17,10-20-12-18-11-19-20)13-4-6-14(16)7-5-13/h4-7,11-12H,2-3,8,10H2,1H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) CD-1 30 Male oral: gavage 24.0000000000 h no data not applicable Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is identical to the substance Myclobutanil 88671-89-0 2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile Myclobutanil C15H17ClN4 Clc1ccc(cc1)C(CCCC)(Cn2cncn2)C#N InChI=1S/C15H17ClN4/c1-2-3-8-15(9-17,10-20-12-18-11-19-20)13-4-6-14(16)7-5-13/h4-7,11-12H,2-3,8,10H2,1H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) CD-1 30 Male oral: gavage 6.0000000000 h no data not applicable Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is identical to the substance Myclobutanil 88671-89-0 2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile Myclobutanil C15H17ClN4 Clc1ccc(cc1)C(CCCC)(Cn2cncn2)C#N InChI=1S/C15H17ClN4/c1-2-3-8-15(9-17,10-20-12-18-11-19-20)13-4-6-14(16)7-5-13/h4-7,11-12H,2-3,8,10H2,1H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) CD-1 42 Male/Female oral: gavage 51.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is identical to the substance Myclobutanil 88671-89-0 2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile Myclobutanil C15H17ClN4 Clc1ccc(cc1)C(CCCC)(Cn2cncn2)C#N InChI=1S/C15H17ClN4/c1-2-3-8-15(9-17,10-20-12-18-11-19-20)13-4-6-14(16)7-5-13/h4-7,11-12H,2-3,8,10H2,1H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) CD-1 42 Male/Female oral: gavage 27.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is identical to the substance Myclobutanil 88671-89-0 2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile Myclobutanil C15H17ClN4 Clc1ccc(cc1)C(CCCC)(Cn2cncn2)C#N InChI=1S/C15H17ClN4/c1-2-3-8-15(9-17,10-20-12-18-11-19-20)13-4-6-14(16)7-5-13/h4-7,11-12H,2-3,8,10H2,1H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) CD-1 42 Male/Female oral: gavage 6.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is identical to the substance Myclobutanil 88671-89-0 2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile Myclobutanil C15H17ClN4 Clc1ccc(cc1)C(CCCC)(Cn2cncn2)C#N InChI=1S/C15H17ClN4/c1-2-3-8-15(9-17,10-20-12-18-11-19-20)13-4-6-14(16)7-5-13/h4-7,11-12H,2-3,8,10H2,1H3 organic compound Other Other chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) Yes Acceptable Rat (as animal) 25 Male oral: gavage yes not applicable Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Tetraconazole 407-760-6 112281-77-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Italy Tetraconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole 16Oct2008 2008 doi:10.2903/j.efsa.2008.152r
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Difenoconazole 601-613-1 119446-68-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Sweden Difenoconazole 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole 07Jan2011 2011 doi:10.2903/j.efsa.2011.1967
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Bitertanol 259-513-5 55179-31-2 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: The United Kingdom Bitertanol 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol 25Oct2010 2010 doi:10.2903/j.efsa.2010.1850
+Myclobutanil 88671-89-0 single chemical entity Component is a metabolite of the substance (3RS)-3-(4-chlorophenyl)-3-cyano-4-(1H-1,2,4-triazol-1-yl)butanoic acid 3-(4-chlorophenyl)-3-cyano-4-(1H-1,2,4-triazol-1-yl)butanoic acid Not in list C13H11ClN4O2 Clc1ccc(cc1)C(CC(=O)O)(Cn2cncn2)C#N InChI=1S/C13H11ClN4O2/c14-11-3-1-10(2-4-11)13(6-15,5-12(19)20)7-18-9-16-8-17-18/h1-4,8-9H,5,7H2,(H,19,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is a metabolite of the substance (3RS)-3-(4-chlorophenyl)-3-cyano-4-(1H-1,2,4-triazol-1-yl)butanoic acid 3-(4-chlorophenyl)-3-cyano-4-(1H-1,2,4-triazol-1-yl)butanoic acid Not in list C13H11ClN4O2 Clc1ccc(cc1)C(CC(=O)O)(Cn2cncn2)C#N InChI=1S/C13H11ClN4O2/c14-11-3-1-10(2-4-11)13(6-15,5-12(19)20)7-18-9-16-8-17-18/h1-4,8-9H,5,7H2,(H,19,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is a metabolite of the substance (3RS)-3-(4-chlorophenyl)-3-cyano-4-(1H-1,2,4-triazol-1-yl)butanoic acid 3-(4-chlorophenyl)-3-cyano-4-(1H-1,2,4-triazol-1-yl)butanoic acid Not in list C13H11ClN4O2 Clc1ccc(cc1)C(CC(=O)O)(Cn2cncn2)C#N InChI=1S/C13H11ClN4O2/c14-11-3-1-10(2-4-11)13(6-15,5-12(19)20)7-18-9-16-8-17-18/h1-4,8-9H,5,7H2,(H,19,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is a metabolite of the substance (3RS)-3-(4-chlorophenyl)-3-cyano-4-(1H-1,2,4-triazol-1-yl)butanoic acid 3-(4-chlorophenyl)-3-cyano-4-(1H-1,2,4-triazol-1-yl)butanoic acid Not in list C13H11ClN4O2 Clc1ccc(cc1)C(CC(=O)O)(Cn2cncn2)C#N InChI=1S/C13H11ClN4O2/c14-11-3-1-10(2-4-11)13(6-15,5-12(19)20)7-18-9-16-8-17-18/h1-4,8-9H,5,7H2,(H,19,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is a metabolite of the substance (3RS)-3-(4-chlorophenyl)-3-cyano-4-(1H-1,2,4-triazol-1-yl)butanoic acid 3-(4-chlorophenyl)-3-cyano-4-(1H-1,2,4-triazol-1-yl)butanoic acid Not in list C13H11ClN4O2 Clc1ccc(cc1)C(CC(=O)O)(Cn2cncn2)C#N InChI=1S/C13H11ClN4O2/c14-11-3-1-10(2-4-11)13(6-15,5-12(19)20)7-18-9-16-8-17-18/h1-4,8-9H,5,7H2,(H,19,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is a metabolite of the substance (3RS)-3-(4-chlorophenyl)-3-cyano-4-(1H-1,2,4-triazol-1-yl)butanoic acid 3-(4-chlorophenyl)-3-cyano-4-(1H-1,2,4-triazol-1-yl)butanoic acid Not in list C13H11ClN4O2 Clc1ccc(cc1)C(CC(=O)O)(Cn2cncn2)C#N InChI=1S/C13H11ClN4O2/c14-11-3-1-10(2-4-11)13(6-15,5-12(19)20)7-18-9-16-8-17-18/h1-4,8-9H,5,7H2,(H,19,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is a metabolite of the substance (3RS)-3-(4-chlorophenyl)-3-cyano-4-(1H-1,2,4-triazol-1-yl)butanoic acid 3-(4-chlorophenyl)-3-cyano-4-(1H-1,2,4-triazol-1-yl)butanoic acid Not in list C13H11ClN4O2 Clc1ccc(cc1)C(CC(=O)O)(Cn2cncn2)C#N InChI=1S/C13H11ClN4O2/c14-11-3-1-10(2-4-11)13(6-15,5-12(19)20)7-18-9-16-8-17-18/h1-4,8-9H,5,7H2,(H,19,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is a metabolite of the substance (3RS)-3-(4-chlorophenyl)-3-cyano-4-(1H-1,2,4-triazol-1-yl)butanoic acid 3-(4-chlorophenyl)-3-cyano-4-(1H-1,2,4-triazol-1-yl)butanoic acid Not in list C13H11ClN4O2 Clc1ccc(cc1)C(CC(=O)O)(Cn2cncn2)C#N InChI=1S/C13H11ClN4O2/c14-11-3-1-10(2-4-11)13(6-15,5-12(19)20)7-18-9-16-8-17-18/h1-4,8-9H,5,7H2,(H,19,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is a metabolite of the substance (3RS)-3-(4-chlorophenyl)-3-cyano-4-(1H-1,2,4-triazol-1-yl)butanoic acid 3-(4-chlorophenyl)-3-cyano-4-(1H-1,2,4-triazol-1-yl)butanoic acid Not in list C13H11ClN4O2 Clc1ccc(cc1)C(CC(=O)O)(Cn2cncn2)C#N InChI=1S/C13H11ClN4O2/c14-11-3-1-10(2-4-11)13(6-15,5-12(19)20)7-18-9-16-8-17-18/h1-4,8-9H,5,7H2,(H,19,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is a metabolite of the substance (3RS)-3-(4-chlorophenyl)-3-cyano-4-(1H-1,2,4-triazol-1-yl)butanoic acid 3-(4-chlorophenyl)-3-cyano-4-(1H-1,2,4-triazol-1-yl)butanoic acid Not in list C13H11ClN4O2 Clc1ccc(cc1)C(CC(=O)O)(Cn2cncn2)C#N InChI=1S/C13H11ClN4O2/c14-11-3-1-10(2-4-11)13(6-15,5-12(19)20)7-18-9-16-8-17-18/h1-4,8-9H,5,7H2,(H,19,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is a metabolite of the substance (3RS)-3-(4-chlorophenyl)-3-cyano-4-(1H-1,2,4-triazol-1-yl)butanoic acid 3-(4-chlorophenyl)-3-cyano-4-(1H-1,2,4-triazol-1-yl)butanoic acid Not in list C13H11ClN4O2 Clc1ccc(cc1)C(CC(=O)O)(Cn2cncn2)C#N InChI=1S/C13H11ClN4O2/c14-11-3-1-10(2-4-11)13(6-15,5-12(19)20)7-18-9-16-8-17-18/h1-4,8-9H,5,7H2,(H,19,20) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is a metabolite of the substance (3RS)-3-(4-chlorophenyl)-3-cyano-4-(1H-1,2,4-triazol-1-yl)butanoic acid 3-(4-chlorophenyl)-3-cyano-4-(1H-1,2,4-triazol-1-yl)butanoic acid Not in list C13H11ClN4O2 Clc1ccc(cc1)C(CC(=O)O)(Cn2cncn2)C#N InChI=1S/C13H11ClN4O2/c14-11-3-1-10(2-4-11)13(6-15,5-12(19)20)7-18-9-16-8-17-18/h1-4,8-9H,5,7H2,(H,19,20) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is a metabolite of the substance (3RS)-3-(4-chlorophenyl)-3-cyano-4-(1H-1,2,4-triazol-1-yl)butanoic acid 3-(4-chlorophenyl)-3-cyano-4-(1H-1,2,4-triazol-1-yl)butanoic acid Not in list C13H11ClN4O2 Clc1ccc(cc1)C(CC(=O)O)(Cn2cncn2)C#N InChI=1S/C13H11ClN4O2/c14-11-3-1-10(2-4-11)13(6-15,5-12(19)20)7-18-9-16-8-17-18/h1-4,8-9H,5,7H2,(H,19,20) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Rat (as animal) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is a metabolite of the substance (3RS)-3-(4-chlorophenyl)-3-cyano-4-(1H-1,2,4-triazol-1-yl)butanoic acid 3-(4-chlorophenyl)-3-cyano-4-(1H-1,2,4-triazol-1-yl)butanoic acid Not in list C13H11ClN4O2 Clc1ccc(cc1)C(CC(=O)O)(Cn2cncn2)C#N InChI=1S/C13H11ClN4O2/c14-11-3-1-10(2-4-11)13(6-15,5-12(19)20)7-18-9-16-8-17-18/h1-4,8-9H,5,7H2,(H,19,20) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Rat (as animal) lymphocytes Not reported yes, concurrent vehicle without Ambiguous RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Myclobutanil 88671-89-0 single chemical entity Component is a metabolite of the substance (3RS)-3-(4-chlorophenyl)-3-cyano-4-(1H-1,2,4-triazol-1-yl)butanoic acid 3-(4-chlorophenyl)-3-cyano-4-(1H-1,2,4-triazol-1-yl)butanoic acid Not in list C13H11ClN4O2 Clc1ccc(cc1)C(CC(=O)O)(Cn2cncn2)C#N InChI=1S/C13H11ClN4O2/c14-11-3-1-10(2-4-11)13(6-15,5-12(19)20)7-18-9-16-8-17-18/h1-4,8-9H,5,7H2,(H,19,20) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 6 Male oral: gavage 48.0000000000 h yes, historical not applicable Negative no evidence RMS: Belgium Myclobutanil (Revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1 29Oct2010 2010 doi:10.2903/j.efsa.2010.1682
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is identical to the substance Metazachlor 266-583-0 67129-08-2 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Metazachlor C14H16ClN3O O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is identical to the substance Metazachlor 266-583-0 67129-08-2 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Metazachlor C14H16ClN3O O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is identical to the substance Metazachlor 266-583-0 67129-08-2 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Metazachlor C14H16ClN3O O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is identical to the substance Metazachlor 266-583-0 67129-08-2 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Metazachlor C14H16ClN3O O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is identical to the substance Metazachlor 266-583-0 67129-08-2 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Metazachlor C14H16ClN3O O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is identical to the substance Metazachlor 266-583-0 67129-08-2 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Metazachlor C14H16ClN3O O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is identical to the substance Metazachlor 266-583-0 67129-08-2 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Metazachlor C14H16ClN3O O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is identical to the substance Metazachlor 266-583-0 67129-08-2 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Metazachlor C14H16ClN3O O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is identical to the substance Metazachlor 266-583-0 67129-08-2 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Metazachlor C14H16ClN3O O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is identical to the substance Metazachlor 266-583-0 67129-08-2 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Metazachlor C14H16ClN3O O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is identical to the substance Metazachlor 266-583-0 67129-08-2 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Metazachlor C14H16ClN3O O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is identical to the substance Metazachlor 266-583-0 67129-08-2 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Metazachlor C14H16ClN3O O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is identical to the substance Metazachlor 266-583-0 67129-08-2 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Metazachlor C14H16ClN3O O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is identical to the substance Metazachlor 266-583-0 67129-08-2 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Metazachlor C14H16ClN3O O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is identical to the substance Metazachlor 266-583-0 67129-08-2 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Metazachlor C14H16ClN3O O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is identical to the substance Metazachlor 266-583-0 67129-08-2 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Metazachlor C14H16ClN3O O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is identical to the substance Metazachlor 266-583-0 67129-08-2 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Metazachlor C14H16ClN3O O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is identical to the substance Metazachlor 266-583-0 67129-08-2 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Metazachlor C14H16ClN3O O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is identical to the substance Metazachlor 266-583-0 67129-08-2 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Metazachlor C14H16ClN3O O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is identical to the substance Metazachlor 266-583-0 67129-08-2 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Metazachlor C14H16ClN3O O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is identical to the substance Metazachlor 266-583-0 67129-08-2 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Metazachlor C14H16ClN3O O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is identical to the substance Metazachlor 266-583-0 67129-08-2 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Metazachlor C14H16ClN3O O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is identical to the substance Metazachlor 266-583-0 67129-08-2 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Metazachlor C14H16ClN3O O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is identical to the substance Metazachlor 266-583-0 67129-08-2 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Metazachlor C14H16ClN3O O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is identical to the substance Metazachlor 266-583-0 67129-08-2 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Metazachlor C14H16ClN3O O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is identical to the substance Metazachlor 266-583-0 67129-08-2 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Metazachlor C14H16ClN3O O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is identical to the substance Metazachlor 266-583-0 67129-08-2 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Metazachlor C14H16ClN3O O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is identical to the substance Metazachlor 266-583-0 67129-08-2 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Metazachlor C14H16ClN3O O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is identical to the substance Metazachlor 266-583-0 67129-08-2 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Metazachlor C14H16ClN3O O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is identical to the substance Metazachlor 266-583-0 67129-08-2 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Metazachlor C14H16ClN3O O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is identical to the substance Metazachlor 266-583-0 67129-08-2 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Metazachlor C14H16ClN3O O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No data Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is identical to the substance Metazachlor 266-583-0 67129-08-2 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Metazachlor C14H16ClN3O O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No data Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is identical to the substance Metazachlor 266-583-0 67129-08-2 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Metazachlor C14H16ClN3O O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Ambiguous small colonies RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is identical to the substance Metazachlor 266-583-0 67129-08-2 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Metazachlor C14H16ClN3O O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Ambiguous large colonies RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is identical to the substance Metazachlor 266-583-0 67129-08-2 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Metazachlor C14H16ClN3O O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Ambiguous large colonies RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is identical to the substance Metazachlor 266-583-0 67129-08-2 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Metazachlor C14H16ClN3O O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Ambiguous small colonies RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is identical to the substance Metazachlor 266-583-0 67129-08-2 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Metazachlor C14H16ClN3O O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent no treatment with Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is identical to the substance Metazachlor 266-583-0 67129-08-2 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Metazachlor C14H16ClN3O O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent no treatment without Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is identical to the substance Metazachlor 266-583-0 67129-08-2 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Metazachlor C14H16ClN3O O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 5 Male intraperitoneal 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is identical to the substance Metazachlor 266-583-0 67129-08-2 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Metazachlor C14H16ClN3O O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 5 Male intraperitoneal 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is identical to the substance Metazachlor 266-583-0 67129-08-2 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Metazachlor C14H16ClN3O O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Swiss 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is identical to the substance Metazachlor 266-583-0 67129-08-2 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Metazachlor C14H16ClN3O O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) Swiss 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Ambiguous RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is identical to the substance Metazachlor 266-583-0 67129-08-2 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Metazachlor C14H16ClN3O O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3 organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vivo No guideline available Not reported Not applicable Acceptable Hamster (as animal) Chinese 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is identical to the substance Metazachlor 266-583-0 67129-08-2 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Metazachlor C14H16ClN3O O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3 organic compound Other Other chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) No data Acceptable House mouse (as animal) CD-1 6 Male oral: gavage 5.0000000000 D yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)oxalamide N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)ethanediamide Not in list C14H16N4O2 O=C(N(Cn1cccn1)c2c(C)cccc2C)C(N)=O InChI=1S/C14H16N4O2/c1-10-5-3-6-11(2)12(10)18(14(20)13(15)19)9-17-8-4-7-16-17/h3-8H,9H2,1-2H3,(H2,15,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)oxalamide N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)ethanediamide Not in list C14H16N4O2 O=C(N(Cn1cccn1)c2c(C)cccc2C)C(N)=O InChI=1S/C14H16N4O2/c1-10-5-3-6-11(2)12(10)18(14(20)13(15)19)9-17-8-4-7-16-17/h3-8H,9H2,1-2H3,(H2,15,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)oxalamide N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)ethanediamide Not in list C14H16N4O2 O=C(N(Cn1cccn1)c2c(C)cccc2C)C(N)=O InChI=1S/C14H16N4O2/c1-10-5-3-6-11(2)12(10)18(14(20)13(15)19)9-17-8-4-7-16-17/h3-8H,9H2,1-2H3,(H2,15,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)oxalamide N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)ethanediamide Not in list C14H16N4O2 O=C(N(Cn1cccn1)c2c(C)cccc2C)C(N)=O InChI=1S/C14H16N4O2/c1-10-5-3-6-11(2)12(10)18(14(20)13(15)19)9-17-8-4-7-16-17/h3-8H,9H2,1-2H3,(H2,15,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)oxalamide N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)ethanediamide Not in list C14H16N4O2 O=C(N(Cn1cccn1)c2c(C)cccc2C)C(N)=O InChI=1S/C14H16N4O2/c1-10-5-3-6-11(2)12(10)18(14(20)13(15)19)9-17-8-4-7-16-17/h3-8H,9H2,1-2H3,(H2,15,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)oxalamide N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)ethanediamide Not in list C14H16N4O2 O=C(N(Cn1cccn1)c2c(C)cccc2C)C(N)=O InChI=1S/C14H16N4O2/c1-10-5-3-6-11(2)12(10)18(14(20)13(15)19)9-17-8-4-7-16-17/h3-8H,9H2,1-2H3,(H2,15,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)oxalamide N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)ethanediamide Not in list C14H16N4O2 O=C(N(Cn1cccn1)c2c(C)cccc2C)C(N)=O InChI=1S/C14H16N4O2/c1-10-5-3-6-11(2)12(10)18(14(20)13(15)19)9-17-8-4-7-16-17/h3-8H,9H2,1-2H3,(H2,15,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)oxalamide N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)ethanediamide Not in list C14H16N4O2 O=C(N(Cn1cccn1)c2c(C)cccc2C)C(N)=O InChI=1S/C14H16N4O2/c1-10-5-3-6-11(2)12(10)18(14(20)13(15)19)9-17-8-4-7-16-17/h3-8H,9H2,1-2H3,(H2,15,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)oxalamide N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)ethanediamide Not in list C14H16N4O2 O=C(N(Cn1cccn1)c2c(C)cccc2C)C(N)=O InChI=1S/C14H16N4O2/c1-10-5-3-6-11(2)12(10)18(14(20)13(15)19)9-17-8-4-7-16-17/h3-8H,9H2,1-2H3,(H2,15,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)oxalamide N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)ethanediamide Not in list C14H16N4O2 O=C(N(Cn1cccn1)c2c(C)cccc2C)C(N)=O InChI=1S/C14H16N4O2/c1-10-5-3-6-11(2)12(10)18(14(20)13(15)19)9-17-8-4-7-16-17/h3-8H,9H2,1-2H3,(H2,15,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)oxalamide N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)ethanediamide Not in list C14H16N4O2 O=C(N(Cn1cccn1)c2c(C)cccc2C)C(N)=O InChI=1S/C14H16N4O2/c1-10-5-3-6-11(2)12(10)18(14(20)13(15)19)9-17-8-4-7-16-17/h3-8H,9H2,1-2H3,(H2,15,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)oxalamide N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)ethanediamide Not in list C14H16N4O2 O=C(N(Cn1cccn1)c2c(C)cccc2C)C(N)=O InChI=1S/C14H16N4O2/c1-10-5-3-6-11(2)12(10)18(14(20)13(15)19)9-17-8-4-7-16-17/h3-8H,9H2,1-2H3,(H2,15,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)oxalamide N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)ethanediamide Not in list C14H16N4O2 O=C(N(Cn1cccn1)c2c(C)cccc2C)C(N)=O InChI=1S/C14H16N4O2/c1-10-5-3-6-11(2)12(10)18(14(20)13(15)19)9-17-8-4-7-16-17/h3-8H,9H2,1-2H3,(H2,15,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)oxalamide N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)ethanediamide Not in list C14H16N4O2 O=C(N(Cn1cccn1)c2c(C)cccc2C)C(N)=O InChI=1S/C14H16N4O2/c1-10-5-3-6-11(2)12(10)18(14(20)13(15)19)9-17-8-4-7-16-17/h3-8H,9H2,1-2H3,(H2,15,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)oxalamide N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)ethanediamide Not in list C14H16N4O2 O=C(N(Cn1cccn1)c2c(C)cccc2C)C(N)=O InChI=1S/C14H16N4O2/c1-10-5-3-6-11(2)12(10)18(14(20)13(15)19)9-17-8-4-7-16-17/h3-8H,9H2,1-2H3,(H2,15,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)oxalamide N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)ethanediamide Not in list C14H16N4O2 O=C(N(Cn1cccn1)c2c(C)cccc2C)C(N)=O InChI=1S/C14H16N4O2/c1-10-5-3-6-11(2)12(10)18(14(20)13(15)19)9-17-8-4-7-16-17/h3-8H,9H2,1-2H3,(H2,15,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)oxalamide N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)ethanediamide Not in list C14H16N4O2 O=C(N(Cn1cccn1)c2c(C)cccc2C)C(N)=O InChI=1S/C14H16N4O2/c1-10-5-3-6-11(2)12(10)18(14(20)13(15)19)9-17-8-4-7-16-17/h3-8H,9H2,1-2H3,(H2,15,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)oxalamide N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)ethanediamide Not in list C14H16N4O2 O=C(N(Cn1cccn1)c2c(C)cccc2C)C(N)=O InChI=1S/C14H16N4O2/c1-10-5-3-6-11(2)12(10)18(14(20)13(15)19)9-17-8-4-7-16-17/h3-8H,9H2,1-2H3,(H2,15,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)oxalamide N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)ethanediamide Not in list C14H16N4O2 O=C(N(Cn1cccn1)c2c(C)cccc2C)C(N)=O InChI=1S/C14H16N4O2/c1-10-5-3-6-11(2)12(10)18(14(20)13(15)19)9-17-8-4-7-16-17/h3-8H,9H2,1-2H3,(H2,15,19) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)oxalamide N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)ethanediamide Not in list C14H16N4O2 O=C(N(Cn1cccn1)c2c(C)cccc2C)C(N)=O InChI=1S/C14H16N4O2/c1-10-5-3-6-11(2)12(10)18(14(20)13(15)19)9-17-8-4-7-16-17/h3-8H,9H2,1-2H3,(H2,15,19) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)oxalamide N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)ethanediamide Not in list C14H16N4O2 O=C(N(Cn1cccn1)c2c(C)cccc2C)C(N)=O InChI=1S/C14H16N4O2/c1-10-5-3-6-11(2)12(10)18(14(20)13(15)19)9-17-8-4-7-16-17/h3-8H,9H2,1-2H3,(H2,15,19) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)oxalamide N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)ethanediamide Not in list C14H16N4O2 O=C(N(Cn1cccn1)c2c(C)cccc2C)C(N)=O InChI=1S/C14H16N4O2/c1-10-5-3-6-11(2)12(10)18(14(20)13(15)19)9-17-8-4-7-16-17/h3-8H,9H2,1-2H3,(H2,15,19) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)oxalamide N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)ethanediamide Not in list C14H16N4O2 O=C(N(Cn1cccn1)c2c(C)cccc2C)C(N)=O InChI=1S/C14H16N4O2/c1-10-5-3-6-11(2)12(10)18(14(20)13(15)19)9-17-8-4-7-16-17/h3-8H,9H2,1-2H3,(H2,15,19) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)oxalamide N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)ethanediamide Not in list C14H16N4O2 O=C(N(Cn1cccn1)c2c(C)cccc2C)C(N)=O InChI=1S/C14H16N4O2/c1-10-5-3-6-11(2)12(10)18(14(20)13(15)19)9-17-8-4-7-16-17/h3-8H,9H2,1-2H3,(H2,15,19) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)oxalamide N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)ethanediamide Not in list C14H16N4O2 O=C(N(Cn1cccn1)c2c(C)cccc2C)C(N)=O InChI=1S/C14H16N4O2/c1-10-5-3-6-11(2)12(10)18(14(20)13(15)19)9-17-8-4-7-16-17/h3-8H,9H2,1-2H3,(H2,15,19) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 72.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfonic acid 2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethanesulfonic acid Not in list C14H17N3O4S O=C(CS(=O)(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H17N3O4S/c1-11-5-3-6-12(2)14(11)17(10-16-8-4-7-15-16)13(18)9-22(19,20)21/h3-8H,9-10H2,1-2H3,(H,19,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes with Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfonic acid 2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethanesulfonic acid Not in list C14H17N3O4S O=C(CS(=O)(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H17N3O4S/c1-11-5-3-6-12(2)14(11)17(10-16-8-4-7-15-16)13(18)9-22(19,20)21/h3-8H,9-10H2,1-2H3,(H,19,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes without Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfonic acid 2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethanesulfonic acid Not in list C14H17N3O4S O=C(CS(=O)(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H17N3O4S/c1-11-5-3-6-12(2)14(11)17(10-16-8-4-7-15-16)13(18)9-22(19,20)21/h3-8H,9-10H2,1-2H3,(H,19,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfonic acid 2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethanesulfonic acid Not in list C14H17N3O4S O=C(CS(=O)(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H17N3O4S/c1-11-5-3-6-12(2)14(11)17(10-16-8-4-7-15-16)13(18)9-22(19,20)21/h3-8H,9-10H2,1-2H3,(H,19,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfonic acid 2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethanesulfonic acid Not in list C14H17N3O4S O=C(CS(=O)(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H17N3O4S/c1-11-5-3-6-12(2)14(11)17(10-16-8-4-7-15-16)13(18)9-22(19,20)21/h3-8H,9-10H2,1-2H3,(H,19,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfonic acid 2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethanesulfonic acid Not in list C14H17N3O4S O=C(CS(=O)(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H17N3O4S/c1-11-5-3-6-12(2)14(11)17(10-16-8-4-7-15-16)13(18)9-22(19,20)21/h3-8H,9-10H2,1-2H3,(H,19,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfonic acid 2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethanesulfonic acid Not in list C14H17N3O4S O=C(CS(=O)(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H17N3O4S/c1-11-5-3-6-12(2)14(11)17(10-16-8-4-7-15-16)13(18)9-22(19,20)21/h3-8H,9-10H2,1-2H3,(H,19,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfonic acid 2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethanesulfonic acid Not in list C14H17N3O4S O=C(CS(=O)(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H17N3O4S/c1-11-5-3-6-12(2)14(11)17(10-16-8-4-7-15-16)13(18)9-22(19,20)21/h3-8H,9-10H2,1-2H3,(H,19,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfonic acid 2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethanesulfonic acid Not in list C14H17N3O4S O=C(CS(=O)(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H17N3O4S/c1-11-5-3-6-12(2)14(11)17(10-16-8-4-7-15-16)13(18)9-22(19,20)21/h3-8H,9-10H2,1-2H3,(H,19,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfonic acid 2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethanesulfonic acid Not in list C14H17N3O4S O=C(CS(=O)(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H17N3O4S/c1-11-5-3-6-12(2)14(11)17(10-16-8-4-7-15-16)13(18)9-22(19,20)21/h3-8H,9-10H2,1-2H3,(H,19,20,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfonic acid 2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethanesulfonic acid Not in list C14H17N3O4S O=C(CS(=O)(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H17N3O4S/c1-11-5-3-6-12(2)14(11)17(10-16-8-4-7-15-16)13(18)9-22(19,20)21/h3-8H,9-10H2,1-2H3,(H,19,20,21) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfonic acid 2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethanesulfonic acid Not in list C14H17N3O4S O=C(CS(=O)(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H17N3O4S/c1-11-5-3-6-12(2)14(11)17(10-16-8-4-7-15-16)13(18)9-22(19,20)21/h3-8H,9-10H2,1-2H3,(H,19,20,21) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfonic acid 2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethanesulfonic acid Not in list C14H17N3O4S O=C(CS(=O)(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H17N3O4S/c1-11-5-3-6-12(2)14(11)17(10-16-8-4-7-15-16)13(18)9-22(19,20)21/h3-8H,9-10H2,1-2H3,(H,19,20,21) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfonic acid 2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethanesulfonic acid Not in list C14H17N3O4S O=C(CS(=O)(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H17N3O4S/c1-11-5-3-6-12(2)14(11)17(10-16-8-4-7-15-16)13(18)9-22(19,20)21/h3-8H,9-10H2,1-2H3,(H,19,20,21) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance sodium N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfonate sodium 2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethanesulfonate Not in list C14H16N3NaO4S O=C(CS(=O)(=O)O[Na])N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H17N3O4S.Na/c1-11-5-3-6-12(2)14(11)17(10-16-8-4-7-15-16)13(18)9-22(19,20)21;/h3-8H,9-10H2,1-2H3,(H,19,20,21);/q;+1/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance sodium N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfonate sodium 2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethanesulfonate Not in list C14H16N3NaO4S O=C(CS(=O)(=O)O[Na])N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H17N3O4S.Na/c1-11-5-3-6-12(2)14(11)17(10-16-8-4-7-15-16)13(18)9-22(19,20)21;/h3-8H,9-10H2,1-2H3,(H,19,20,21);/q;+1/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance sodium N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfonate sodium 2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethanesulfonate Not in list C14H16N3NaO4S O=C(CS(=O)(=O)O[Na])N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H17N3O4S.Na/c1-11-5-3-6-12(2)14(11)17(10-16-8-4-7-15-16)13(18)9-22(19,20)21;/h3-8H,9-10H2,1-2H3,(H,19,20,21);/q;+1/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance sodium N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfonate sodium 2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethanesulfonate Not in list C14H16N3NaO4S O=C(CS(=O)(=O)O[Na])N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H17N3O4S.Na/c1-11-5-3-6-12(2)14(11)17(10-16-8-4-7-15-16)13(18)9-22(19,20)21;/h3-8H,9-10H2,1-2H3,(H,19,20,21);/q;+1/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance sodium N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfonate sodium 2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethanesulfonate Not in list C14H16N3NaO4S O=C(CS(=O)(=O)O[Na])N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H17N3O4S.Na/c1-11-5-3-6-12(2)14(11)17(10-16-8-4-7-15-16)13(18)9-22(19,20)21;/h3-8H,9-10H2,1-2H3,(H,19,20,21);/q;+1/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance sodium N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfonate sodium 2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethanesulfonate Not in list C14H16N3NaO4S O=C(CS(=O)(=O)O[Na])N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H17N3O4S.Na/c1-11-5-3-6-12(2)14(11)17(10-16-8-4-7-15-16)13(18)9-22(19,20)21;/h3-8H,9-10H2,1-2H3,(H,19,20,21);/q;+1/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance sodium N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfonate sodium 2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethanesulfonate Not in list C14H16N3NaO4S O=C(CS(=O)(=O)O[Na])N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H17N3O4S.Na/c1-11-5-3-6-12(2)14(11)17(10-16-8-4-7-15-16)13(18)9-22(19,20)21;/h3-8H,9-10H2,1-2H3,(H,19,20,21);/q;+1/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance sodium N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfonate sodium 2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethanesulfonate Not in list C14H16N3NaO4S O=C(CS(=O)(=O)O[Na])N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H17N3O4S.Na/c1-11-5-3-6-12(2)14(11)17(10-16-8-4-7-15-16)13(18)9-22(19,20)21;/h3-8H,9-10H2,1-2H3,(H,19,20,21);/q;+1/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance sodium N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfonate sodium 2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethanesulfonate Not in list C14H16N3NaO4S O=C(CS(=O)(=O)O[Na])N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H17N3O4S.Na/c1-11-5-3-6-12(2)14(11)17(10-16-8-4-7-15-16)13(18)9-22(19,20)21;/h3-8H,9-10H2,1-2H3,(H,19,20,21);/q;+1/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance sodium N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfonate sodium 2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethanesulfonate Not in list C14H16N3NaO4S O=C(CS(=O)(=O)O[Na])N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H17N3O4S.Na/c1-11-5-3-6-12(2)14(11)17(10-16-8-4-7-15-16)13(18)9-22(19,20)21;/h3-8H,9-10H2,1-2H3,(H,19,20,21);/q;+1/p-1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance sodium N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfonate sodium 2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethanesulfonate Not in list C14H16N3NaO4S O=C(CS(=O)(=O)O[Na])N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H17N3O4S.Na/c1-11-5-3-6-12(2)14(11)17(10-16-8-4-7-15-16)13(18)9-22(19,20)21;/h3-8H,9-10H2,1-2H3,(H,19,20,21);/q;+1/p-1 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance sodium N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfonate sodium 2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethanesulfonate Not in list C14H16N3NaO4S O=C(CS(=O)(=O)O[Na])N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H17N3O4S.Na/c1-11-5-3-6-12(2)14(11)17(10-16-8-4-7-15-16)13(18)9-22(19,20)21;/h3-8H,9-10H2,1-2H3,(H,19,20,21);/q;+1/p-1 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance sodium N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfonate sodium 2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethanesulfonate Not in list C14H16N3NaO4S O=C(CS(=O)(=O)O[Na])N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H17N3O4S.Na/c1-11-5-3-6-12(2)14(11)17(10-16-8-4-7-15-16)13(18)9-22(19,20)21;/h3-8H,9-10H2,1-2H3,(H,19,20,21);/q;+1/p-1 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 5 Male intraperitoneal 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl acetic acid ({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)acetic acid Not in list C16H19N3O4S O=C(CS(=O)CC(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C16H19N3O4S/c1-12-5-3-6-13(2)16(12)19(11-18-8-4-7-17-18)14(20)9-24(23)10-15(21)22/h3-8H,9-11H2,1-2H3,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl acetic acid ({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)acetic acid Not in list C16H19N3O4S O=C(CS(=O)CC(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C16H19N3O4S/c1-12-5-3-6-13(2)16(12)19(11-18-8-4-7-17-18)14(20)9-24(23)10-15(21)22/h3-8H,9-11H2,1-2H3,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl acetic acid ({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)acetic acid Not in list C16H19N3O4S O=C(CS(=O)CC(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C16H19N3O4S/c1-12-5-3-6-13(2)16(12)19(11-18-8-4-7-17-18)14(20)9-24(23)10-15(21)22/h3-8H,9-11H2,1-2H3,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl acetic acid ({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)acetic acid Not in list C16H19N3O4S O=C(CS(=O)CC(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C16H19N3O4S/c1-12-5-3-6-13(2)16(12)19(11-18-8-4-7-17-18)14(20)9-24(23)10-15(21)22/h3-8H,9-11H2,1-2H3,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl acetic acid ({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)acetic acid Not in list C16H19N3O4S O=C(CS(=O)CC(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C16H19N3O4S/c1-12-5-3-6-13(2)16(12)19(11-18-8-4-7-17-18)14(20)9-24(23)10-15(21)22/h3-8H,9-11H2,1-2H3,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl acetic acid ({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)acetic acid Not in list C16H19N3O4S O=C(CS(=O)CC(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C16H19N3O4S/c1-12-5-3-6-13(2)16(12)19(11-18-8-4-7-17-18)14(20)9-24(23)10-15(21)22/h3-8H,9-11H2,1-2H3,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl acetic acid ({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)acetic acid Not in list C16H19N3O4S O=C(CS(=O)CC(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C16H19N3O4S/c1-12-5-3-6-13(2)16(12)19(11-18-8-4-7-17-18)14(20)9-24(23)10-15(21)22/h3-8H,9-11H2,1-2H3,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl acetic acid ({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)acetic acid Not in list C16H19N3O4S O=C(CS(=O)CC(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C16H19N3O4S/c1-12-5-3-6-13(2)16(12)19(11-18-8-4-7-17-18)14(20)9-24(23)10-15(21)22/h3-8H,9-11H2,1-2H3,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl acetic acid ({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)acetic acid Not in list C16H19N3O4S O=C(CS(=O)CC(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C16H19N3O4S/c1-12-5-3-6-13(2)16(12)19(11-18-8-4-7-17-18)14(20)9-24(23)10-15(21)22/h3-8H,9-11H2,1-2H3,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl acetic acid ({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)acetic acid Not in list C16H19N3O4S O=C(CS(=O)CC(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C16H19N3O4S/c1-12-5-3-6-13(2)16(12)19(11-18-8-4-7-17-18)14(20)9-24(23)10-15(21)22/h3-8H,9-11H2,1-2H3,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl acetic acid ({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)acetic acid Not in list C16H19N3O4S O=C(CS(=O)CC(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C16H19N3O4S/c1-12-5-3-6-13(2)16(12)19(11-18-8-4-7-17-18)14(20)9-24(23)10-15(21)22/h3-8H,9-11H2,1-2H3,(H,21,22) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl acetic acid ({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)acetic acid Not in list C16H19N3O4S O=C(CS(=O)CC(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C16H19N3O4S/c1-12-5-3-6-13(2)16(12)19(11-18-8-4-7-17-18)14(20)9-24(23)10-15(21)22/h3-8H,9-11H2,1-2H3,(H,21,22) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl acetic acid ({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)acetic acid Not in list C16H19N3O4S O=C(CS(=O)CC(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C16H19N3O4S/c1-12-5-3-6-13(2)16(12)19(11-18-8-4-7-17-18)14(20)9-24(23)10-15(21)22/h3-8H,9-11H2,1-2H3,(H,21,22) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl acetic acid ({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)acetic acid Not in list C16H19N3O4S O=C(CS(=O)CC(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C16H19N3O4S/c1-12-5-3-6-13(2)16(12)19(11-18-8-4-7-17-18)14(20)9-24(23)10-15(21)22/h3-8H,9-11H2,1-2H3,(H,21,22) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance methyl N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfoxide N-(2,6-dimethylphenyl)-2-(methylsulfinyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Not in list C15H19N3O2S O=C(CS(C)=O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C15H19N3O2S/c1-12-6-4-7-13(2)15(12)18(14(19)10-21(3)20)11-17-9-5-8-16-17/h4-9H,10-11H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance methyl N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfoxide N-(2,6-dimethylphenyl)-2-(methylsulfinyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Not in list C15H19N3O2S O=C(CS(C)=O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C15H19N3O2S/c1-12-6-4-7-13(2)15(12)18(14(19)10-21(3)20)11-17-9-5-8-16-17/h4-9H,10-11H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance methyl N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfoxide N-(2,6-dimethylphenyl)-2-(methylsulfinyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Not in list C15H19N3O2S O=C(CS(C)=O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C15H19N3O2S/c1-12-6-4-7-13(2)15(12)18(14(19)10-21(3)20)11-17-9-5-8-16-17/h4-9H,10-11H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance methyl N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfoxide N-(2,6-dimethylphenyl)-2-(methylsulfinyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Not in list C15H19N3O2S O=C(CS(C)=O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C15H19N3O2S/c1-12-6-4-7-13(2)15(12)18(14(19)10-21(3)20)11-17-9-5-8-16-17/h4-9H,10-11H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance methyl N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfoxide N-(2,6-dimethylphenyl)-2-(methylsulfinyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Not in list C15H19N3O2S O=C(CS(C)=O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C15H19N3O2S/c1-12-6-4-7-13(2)15(12)18(14(19)10-21(3)20)11-17-9-5-8-16-17/h4-9H,10-11H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance methyl N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfoxide N-(2,6-dimethylphenyl)-2-(methylsulfinyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Not in list C15H19N3O2S O=C(CS(C)=O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C15H19N3O2S/c1-12-6-4-7-13(2)15(12)18(14(19)10-21(3)20)11-17-9-5-8-16-17/h4-9H,10-11H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance methyl N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfoxide N-(2,6-dimethylphenyl)-2-(methylsulfinyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Not in list C15H19N3O2S O=C(CS(C)=O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C15H19N3O2S/c1-12-6-4-7-13(2)15(12)18(14(19)10-21(3)20)11-17-9-5-8-16-17/h4-9H,10-11H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance methyl N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfoxide N-(2,6-dimethylphenyl)-2-(methylsulfinyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Not in list C15H19N3O2S O=C(CS(C)=O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C15H19N3O2S/c1-12-6-4-7-13(2)15(12)18(14(19)10-21(3)20)11-17-9-5-8-16-17/h4-9H,10-11H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance methyl N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfoxide N-(2,6-dimethylphenyl)-2-(methylsulfinyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Not in list C15H19N3O2S O=C(CS(C)=O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C15H19N3O2S/c1-12-6-4-7-13(2)15(12)18(14(19)10-21(3)20)11-17-9-5-8-16-17/h4-9H,10-11H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance methyl N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfoxide N-(2,6-dimethylphenyl)-2-(methylsulfinyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Not in list C15H19N3O2S O=C(CS(C)=O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C15H19N3O2S/c1-12-6-4-7-13(2)15(12)18(14(19)10-21(3)20)11-17-9-5-8-16-17/h4-9H,10-11H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-[(2-hydroxycarbonyl-6-methyl)phenyl]-N-(1H-pyrazol-1-ylmethyl)oxalamide 2-[(carboxycarbonyl)(1H-pyrazol-1-ylmethyl)amino]-3-methylbenzoic acid Not in list C14H13N3O5 O=C(N(Cn1cccn1)c2c(C)cccc2C(=O)O)C(=O)O InChI=1S/C14H13N3O5/c1-9-4-2-5-10(13(19)20)11(9)17(12(18)14(21)22)8-16-7-3-6-15-16/h2-7H,8H2,1H3,(H,19,20)(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-[(2-hydroxycarbonyl-6-methyl)phenyl]-N-(1H-pyrazol-1-ylmethyl)oxalamide 2-[(carboxycarbonyl)(1H-pyrazol-1-ylmethyl)amino]-3-methylbenzoic acid Not in list C14H13N3O5 O=C(N(Cn1cccn1)c2c(C)cccc2C(=O)O)C(=O)O InChI=1S/C14H13N3O5/c1-9-4-2-5-10(13(19)20)11(9)17(12(18)14(21)22)8-16-7-3-6-15-16/h2-7H,8H2,1H3,(H,19,20)(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-[(2-hydroxycarbonyl-6-methyl)phenyl]-N-(1H-pyrazol-1-ylmethyl)oxalamide 2-[(carboxycarbonyl)(1H-pyrazol-1-ylmethyl)amino]-3-methylbenzoic acid Not in list C14H13N3O5 O=C(N(Cn1cccn1)c2c(C)cccc2C(=O)O)C(=O)O InChI=1S/C14H13N3O5/c1-9-4-2-5-10(13(19)20)11(9)17(12(18)14(21)22)8-16-7-3-6-15-16/h2-7H,8H2,1H3,(H,19,20)(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-[(2-hydroxycarbonyl-6-methyl)phenyl]-N-(1H-pyrazol-1-ylmethyl)oxalamide 2-[(carboxycarbonyl)(1H-pyrazol-1-ylmethyl)amino]-3-methylbenzoic acid Not in list C14H13N3O5 O=C(N(Cn1cccn1)c2c(C)cccc2C(=O)O)C(=O)O InChI=1S/C14H13N3O5/c1-9-4-2-5-10(13(19)20)11(9)17(12(18)14(21)22)8-16-7-3-6-15-16/h2-7H,8H2,1H3,(H,19,20)(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-[(2-hydroxycarbonyl-6-methyl)phenyl]-N-(1H-pyrazol-1-ylmethyl)oxalamide 2-[(carboxycarbonyl)(1H-pyrazol-1-ylmethyl)amino]-3-methylbenzoic acid Not in list C14H13N3O5 O=C(N(Cn1cccn1)c2c(C)cccc2C(=O)O)C(=O)O InChI=1S/C14H13N3O5/c1-9-4-2-5-10(13(19)20)11(9)17(12(18)14(21)22)8-16-7-3-6-15-16/h2-7H,8H2,1H3,(H,19,20)(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-[(2-hydroxycarbonyl-6-methyl)phenyl]-N-(1H-pyrazol-1-ylmethyl)oxalamide 2-[(carboxycarbonyl)(1H-pyrazol-1-ylmethyl)amino]-3-methylbenzoic acid Not in list C14H13N3O5 O=C(N(Cn1cccn1)c2c(C)cccc2C(=O)O)C(=O)O InChI=1S/C14H13N3O5/c1-9-4-2-5-10(13(19)20)11(9)17(12(18)14(21)22)8-16-7-3-6-15-16/h2-7H,8H2,1H3,(H,19,20)(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-[(2-hydroxycarbonyl-6-methyl)phenyl]-N-(1H-pyrazol-1-ylmethyl)oxalamide 2-[(carboxycarbonyl)(1H-pyrazol-1-ylmethyl)amino]-3-methylbenzoic acid Not in list C14H13N3O5 O=C(N(Cn1cccn1)c2c(C)cccc2C(=O)O)C(=O)O InChI=1S/C14H13N3O5/c1-9-4-2-5-10(13(19)20)11(9)17(12(18)14(21)22)8-16-7-3-6-15-16/h2-7H,8H2,1H3,(H,19,20)(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-[(2-hydroxycarbonyl-6-methyl)phenyl]-N-(1H-pyrazol-1-ylmethyl)oxalamide 2-[(carboxycarbonyl)(1H-pyrazol-1-ylmethyl)amino]-3-methylbenzoic acid Not in list C14H13N3O5 O=C(N(Cn1cccn1)c2c(C)cccc2C(=O)O)C(=O)O InChI=1S/C14H13N3O5/c1-9-4-2-5-10(13(19)20)11(9)17(12(18)14(21)22)8-16-7-3-6-15-16/h2-7H,8H2,1H3,(H,19,20)(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-[(2-hydroxycarbonyl-6-methyl)phenyl]-N-(1H-pyrazol-1-ylmethyl)oxalamide 2-[(carboxycarbonyl)(1H-pyrazol-1-ylmethyl)amino]-3-methylbenzoic acid Not in list C14H13N3O5 O=C(N(Cn1cccn1)c2c(C)cccc2C(=O)O)C(=O)O InChI=1S/C14H13N3O5/c1-9-4-2-5-10(13(19)20)11(9)17(12(18)14(21)22)8-16-7-3-6-15-16/h2-7H,8H2,1H3,(H,19,20)(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-[(2-hydroxycarbonyl-6-methyl)phenyl]-N-(1H-pyrazol-1-ylmethyl)oxalamide 2-[(carboxycarbonyl)(1H-pyrazol-1-ylmethyl)amino]-3-methylbenzoic acid Not in list C14H13N3O5 O=C(N(Cn1cccn1)c2c(C)cccc2C(=O)O)C(=O)O InChI=1S/C14H13N3O5/c1-9-4-2-5-10(13(19)20)11(9)17(12(18)14(21)22)8-16-7-3-6-15-16/h2-7H,8H2,1H3,(H,19,20)(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance 3-[N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl]-2-hydroxypropanoic acid 3-({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)-2-hydroxypropanoic acid Not in list C17H21N3O5S O=C(CS(=O)CC(O)C(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C17H21N3O5S/c1-12-5-3-6-13(2)16(12)20(11-19-8-4-7-18-19)15(22)10-26(25)9-14(21)17(23)24/h3-8,14,21H,9-11H2,1-2H3,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance 3-[N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl]-2-hydroxypropanoic acid 3-({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)-2-hydroxypropanoic acid Not in list C17H21N3O5S O=C(CS(=O)CC(O)C(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C17H21N3O5S/c1-12-5-3-6-13(2)16(12)20(11-19-8-4-7-18-19)15(22)10-26(25)9-14(21)17(23)24/h3-8,14,21H,9-11H2,1-2H3,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance 3-[N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl]-2-hydroxypropanoic acid 3-({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)-2-hydroxypropanoic acid Not in list C17H21N3O5S O=C(CS(=O)CC(O)C(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C17H21N3O5S/c1-12-5-3-6-13(2)16(12)20(11-19-8-4-7-18-19)15(22)10-26(25)9-14(21)17(23)24/h3-8,14,21H,9-11H2,1-2H3,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance 3-[N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl]-2-hydroxypropanoic acid 3-({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)-2-hydroxypropanoic acid Not in list C17H21N3O5S O=C(CS(=O)CC(O)C(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C17H21N3O5S/c1-12-5-3-6-13(2)16(12)20(11-19-8-4-7-18-19)15(22)10-26(25)9-14(21)17(23)24/h3-8,14,21H,9-11H2,1-2H3,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance 3-[N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl]-2-hydroxypropanoic acid 3-({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)-2-hydroxypropanoic acid Not in list C17H21N3O5S O=C(CS(=O)CC(O)C(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C17H21N3O5S/c1-12-5-3-6-13(2)16(12)20(11-19-8-4-7-18-19)15(22)10-26(25)9-14(21)17(23)24/h3-8,14,21H,9-11H2,1-2H3,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance 3-[N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl]-2-hydroxypropanoic acid 3-({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)-2-hydroxypropanoic acid Not in list C17H21N3O5S O=C(CS(=O)CC(O)C(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C17H21N3O5S/c1-12-5-3-6-13(2)16(12)20(11-19-8-4-7-18-19)15(22)10-26(25)9-14(21)17(23)24/h3-8,14,21H,9-11H2,1-2H3,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance 3-[N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl]-2-hydroxypropanoic acid 3-({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)-2-hydroxypropanoic acid Not in list C17H21N3O5S O=C(CS(=O)CC(O)C(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C17H21N3O5S/c1-12-5-3-6-13(2)16(12)20(11-19-8-4-7-18-19)15(22)10-26(25)9-14(21)17(23)24/h3-8,14,21H,9-11H2,1-2H3,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance 3-[N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl]-2-hydroxypropanoic acid 3-({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)-2-hydroxypropanoic acid Not in list C17H21N3O5S O=C(CS(=O)CC(O)C(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C17H21N3O5S/c1-12-5-3-6-13(2)16(12)20(11-19-8-4-7-18-19)15(22)10-26(25)9-14(21)17(23)24/h3-8,14,21H,9-11H2,1-2H3,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance 3-[N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl]-2-hydroxypropanoic acid 3-({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)-2-hydroxypropanoic acid Not in list C17H21N3O5S O=C(CS(=O)CC(O)C(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C17H21N3O5S/c1-12-5-3-6-13(2)16(12)20(11-19-8-4-7-18-19)15(22)10-26(25)9-14(21)17(23)24/h3-8,14,21H,9-11H2,1-2H3,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance 3-[N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl]-2-hydroxypropanoic acid 3-({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)-2-hydroxypropanoic acid Not in list C17H21N3O5S O=C(CS(=O)CC(O)C(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C17H21N3O5S/c1-12-5-3-6-13(2)16(12)20(11-19-8-4-7-18-19)15(22)10-26(25)9-14(21)17(23)24/h3-8,14,21H,9-11H2,1-2H3,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance 3-[N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl]-2-hydroxypropanoic acid 3-({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)-2-hydroxypropanoic acid Not in list C17H21N3O5S O=C(CS(=O)CC(O)C(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C17H21N3O5S/c1-12-5-3-6-13(2)16(12)20(11-19-8-4-7-18-19)15(22)10-26(25)9-14(21)17(23)24/h3-8,14,21H,9-11H2,1-2H3,(H,23,24) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance 3-[N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl]-2-hydroxypropanoic acid 3-({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)-2-hydroxypropanoic acid Not in list C17H21N3O5S O=C(CS(=O)CC(O)C(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C17H21N3O5S/c1-12-5-3-6-13(2)16(12)20(11-19-8-4-7-18-19)15(22)10-26(25)9-14(21)17(23)24/h3-8,14,21H,9-11H2,1-2H3,(H,23,24) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance 3-[N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl]-2-hydroxypropanoic acid 3-({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)-2-hydroxypropanoic acid Not in list C17H21N3O5S O=C(CS(=O)CC(O)C(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C17H21N3O5S/c1-12-5-3-6-13(2)16(12)20(11-19-8-4-7-18-19)15(22)10-26(25)9-14(21)17(23)24/h3-8,14,21H,9-11H2,1-2H3,(H,23,24) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance 3-[N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl]-2-hydroxypropanoic acid 3-({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)-2-hydroxypropanoic acid Not in list C17H21N3O5S O=C(CS(=O)CC(O)C(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C17H21N3O5S/c1-12-5-3-6-13(2)16(12)20(11-19-8-4-7-18-19)15(22)10-26(25)9-14(21)17(23)24/h3-8,14,21H,9-11H2,1-2H3,(H,23,24) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is identical to the substance Metazachlor 266-583-0 67129-08-2 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Metazachlor C14H16ClN3O O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is identical to the substance Metazachlor 266-583-0 67129-08-2 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Metazachlor C14H16ClN3O O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is identical to the substance Metazachlor 266-583-0 67129-08-2 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Metazachlor C14H16ClN3O O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is identical to the substance Metazachlor 266-583-0 67129-08-2 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Metazachlor C14H16ClN3O O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is identical to the substance Metazachlor 266-583-0 67129-08-2 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Metazachlor C14H16ClN3O O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is identical to the substance Metazachlor 266-583-0 67129-08-2 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Metazachlor C14H16ClN3O O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is identical to the substance Metazachlor 266-583-0 67129-08-2 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Metazachlor C14H16ClN3O O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is identical to the substance Metazachlor 266-583-0 67129-08-2 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Metazachlor C14H16ClN3O O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is identical to the substance Metazachlor 266-583-0 67129-08-2 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Metazachlor C14H16ClN3O O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is identical to the substance Metazachlor 266-583-0 67129-08-2 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Metazachlor C14H16ClN3O O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is identical to the substance Metazachlor 266-583-0 67129-08-2 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Metazachlor C14H16ClN3O O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is identical to the substance Metazachlor 266-583-0 67129-08-2 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Metazachlor C14H16ClN3O O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is identical to the substance Metazachlor 266-583-0 67129-08-2 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Metazachlor C14H16ClN3O O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is identical to the substance Metazachlor 266-583-0 67129-08-2 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Metazachlor C14H16ClN3O O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is identical to the substance Metazachlor 266-583-0 67129-08-2 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Metazachlor C14H16ClN3O O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is identical to the substance Metazachlor 266-583-0 67129-08-2 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Metazachlor C14H16ClN3O O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is identical to the substance Metazachlor 266-583-0 67129-08-2 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Metazachlor C14H16ClN3O O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is identical to the substance Metazachlor 266-583-0 67129-08-2 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Metazachlor C14H16ClN3O O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is identical to the substance Metazachlor 266-583-0 67129-08-2 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Metazachlor C14H16ClN3O O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is identical to the substance Metazachlor 266-583-0 67129-08-2 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Metazachlor C14H16ClN3O O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl acetic acid ({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)acetic acid Not in list C16H19N3O4S O=C(CS(=O)CC(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C16H19N3O4S/c1-12-5-3-6-13(2)16(12)19(11-18-8-4-7-17-18)14(20)9-24(23)10-15(21)22/h3-8H,9-11H2,1-2H3,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl acetic acid ({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)acetic acid Not in list C16H19N3O4S O=C(CS(=O)CC(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C16H19N3O4S/c1-12-5-3-6-13(2)16(12)19(11-18-8-4-7-17-18)14(20)9-24(23)10-15(21)22/h3-8H,9-11H2,1-2H3,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl acetic acid ({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)acetic acid Not in list C16H19N3O4S O=C(CS(=O)CC(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C16H19N3O4S/c1-12-5-3-6-13(2)16(12)19(11-18-8-4-7-17-18)14(20)9-24(23)10-15(21)22/h3-8H,9-11H2,1-2H3,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl acetic acid ({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)acetic acid Not in list C16H19N3O4S O=C(CS(=O)CC(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C16H19N3O4S/c1-12-5-3-6-13(2)16(12)19(11-18-8-4-7-17-18)14(20)9-24(23)10-15(21)22/h3-8H,9-11H2,1-2H3,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl acetic acid ({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)acetic acid Not in list C16H19N3O4S O=C(CS(=O)CC(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C16H19N3O4S/c1-12-5-3-6-13(2)16(12)19(11-18-8-4-7-17-18)14(20)9-24(23)10-15(21)22/h3-8H,9-11H2,1-2H3,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl acetic acid ({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)acetic acid Not in list C16H19N3O4S O=C(CS(=O)CC(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C16H19N3O4S/c1-12-5-3-6-13(2)16(12)19(11-18-8-4-7-17-18)14(20)9-24(23)10-15(21)22/h3-8H,9-11H2,1-2H3,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl acetic acid ({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)acetic acid Not in list C16H19N3O4S O=C(CS(=O)CC(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C16H19N3O4S/c1-12-5-3-6-13(2)16(12)19(11-18-8-4-7-17-18)14(20)9-24(23)10-15(21)22/h3-8H,9-11H2,1-2H3,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl acetic acid ({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)acetic acid Not in list C16H19N3O4S O=C(CS(=O)CC(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C16H19N3O4S/c1-12-5-3-6-13(2)16(12)19(11-18-8-4-7-17-18)14(20)9-24(23)10-15(21)22/h3-8H,9-11H2,1-2H3,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl acetic acid ({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)acetic acid Not in list C16H19N3O4S O=C(CS(=O)CC(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C16H19N3O4S/c1-12-5-3-6-13(2)16(12)19(11-18-8-4-7-17-18)14(20)9-24(23)10-15(21)22/h3-8H,9-11H2,1-2H3,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl acetic acid ({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)acetic acid Not in list C16H19N3O4S O=C(CS(=O)CC(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C16H19N3O4S/c1-12-5-3-6-13(2)16(12)19(11-18-8-4-7-17-18)14(20)9-24(23)10-15(21)22/h3-8H,9-11H2,1-2H3,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl acetic acid ({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)acetic acid Not in list C16H19N3O4S O=C(CS(=O)CC(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C16H19N3O4S/c1-12-5-3-6-13(2)16(12)19(11-18-8-4-7-17-18)14(20)9-24(23)10-15(21)22/h3-8H,9-11H2,1-2H3,(H,21,22) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative large colonies RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl acetic acid ({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)acetic acid Not in list C16H19N3O4S O=C(CS(=O)CC(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C16H19N3O4S/c1-12-5-3-6-13(2)16(12)19(11-18-8-4-7-17-18)14(20)9-24(23)10-15(21)22/h3-8H,9-11H2,1-2H3,(H,21,22) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative small colonies RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl acetic acid ({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)acetic acid Not in list C16H19N3O4S O=C(CS(=O)CC(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C16H19N3O4S/c1-12-5-3-6-13(2)16(12)19(11-18-8-4-7-17-18)14(20)9-24(23)10-15(21)22/h3-8H,9-11H2,1-2H3,(H,21,22) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative small colonies RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl acetic acid ({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)acetic acid Not in list C16H19N3O4S O=C(CS(=O)CC(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C16H19N3O4S/c1-12-5-3-6-13(2)16(12)19(11-18-8-4-7-17-18)14(20)9-24(23)10-15(21)22/h3-8H,9-11H2,1-2H3,(H,21,22) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative large colonies RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl acetic acid ({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)acetic acid Not in list C16H19N3O4S O=C(CS(=O)CC(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C16H19N3O4S/c1-12-5-3-6-13(2)16(12)19(11-18-8-4-7-17-18)14(20)9-24(23)10-15(21)22/h3-8H,9-11H2,1-2H3,(H,21,22) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl acetic acid ({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)acetic acid Not in list C16H19N3O4S O=C(CS(=O)CC(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C16H19N3O4S/c1-12-5-3-6-13(2)16(12)19(11-18-8-4-7-17-18)14(20)9-24(23)10-15(21)22/h3-8H,9-11H2,1-2H3,(H,21,22) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance methyl N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfoxide N-(2,6-dimethylphenyl)-2-(methylsulfinyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Not in list C15H19N3O2S O=C(CS(C)=O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C15H19N3O2S/c1-12-6-4-7-13(2)15(12)18(14(19)10-21(3)20)11-17-9-5-8-16-17/h4-9H,10-11H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance methyl N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfoxide N-(2,6-dimethylphenyl)-2-(methylsulfinyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Not in list C15H19N3O2S O=C(CS(C)=O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C15H19N3O2S/c1-12-6-4-7-13(2)15(12)18(14(19)10-21(3)20)11-17-9-5-8-16-17/h4-9H,10-11H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance methyl N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfoxide N-(2,6-dimethylphenyl)-2-(methylsulfinyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Not in list C15H19N3O2S O=C(CS(C)=O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C15H19N3O2S/c1-12-6-4-7-13(2)15(12)18(14(19)10-21(3)20)11-17-9-5-8-16-17/h4-9H,10-11H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance methyl N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfoxide N-(2,6-dimethylphenyl)-2-(methylsulfinyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Not in list C15H19N3O2S O=C(CS(C)=O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C15H19N3O2S/c1-12-6-4-7-13(2)15(12)18(14(19)10-21(3)20)11-17-9-5-8-16-17/h4-9H,10-11H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance methyl N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfoxide N-(2,6-dimethylphenyl)-2-(methylsulfinyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Not in list C15H19N3O2S O=C(CS(C)=O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C15H19N3O2S/c1-12-6-4-7-13(2)15(12)18(14(19)10-21(3)20)11-17-9-5-8-16-17/h4-9H,10-11H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance methyl N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfoxide N-(2,6-dimethylphenyl)-2-(methylsulfinyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Not in list C15H19N3O2S O=C(CS(C)=O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C15H19N3O2S/c1-12-6-4-7-13(2)15(12)18(14(19)10-21(3)20)11-17-9-5-8-16-17/h4-9H,10-11H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance methyl N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfoxide N-(2,6-dimethylphenyl)-2-(methylsulfinyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Not in list C15H19N3O2S O=C(CS(C)=O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C15H19N3O2S/c1-12-6-4-7-13(2)15(12)18(14(19)10-21(3)20)11-17-9-5-8-16-17/h4-9H,10-11H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance methyl N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfoxide N-(2,6-dimethylphenyl)-2-(methylsulfinyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Not in list C15H19N3O2S O=C(CS(C)=O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C15H19N3O2S/c1-12-6-4-7-13(2)15(12)18(14(19)10-21(3)20)11-17-9-5-8-16-17/h4-9H,10-11H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance methyl N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfoxide N-(2,6-dimethylphenyl)-2-(methylsulfinyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Not in list C15H19N3O2S O=C(CS(C)=O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C15H19N3O2S/c1-12-6-4-7-13(2)15(12)18(14(19)10-21(3)20)11-17-9-5-8-16-17/h4-9H,10-11H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance methyl N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfoxide N-(2,6-dimethylphenyl)-2-(methylsulfinyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Not in list C15H19N3O2S O=C(CS(C)=O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C15H19N3O2S/c1-12-6-4-7-13(2)15(12)18(14(19)10-21(3)20)11-17-9-5-8-16-17/h4-9H,10-11H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance methyl N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfoxide N-(2,6-dimethylphenyl)-2-(methylsulfinyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Not in list C15H19N3O2S O=C(CS(C)=O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C15H19N3O2S/c1-12-6-4-7-13(2)15(12)18(14(19)10-21(3)20)11-17-9-5-8-16-17/h4-9H,10-11H2,1-3H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative small colonies RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance methyl N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfoxide N-(2,6-dimethylphenyl)-2-(methylsulfinyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Not in list C15H19N3O2S O=C(CS(C)=O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C15H19N3O2S/c1-12-6-4-7-13(2)15(12)18(14(19)10-21(3)20)11-17-9-5-8-16-17/h4-9H,10-11H2,1-3H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative large colonies RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance methyl N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfoxide N-(2,6-dimethylphenyl)-2-(methylsulfinyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Not in list C15H19N3O2S O=C(CS(C)=O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C15H19N3O2S/c1-12-6-4-7-13(2)15(12)18(14(19)10-21(3)20)11-17-9-5-8-16-17/h4-9H,10-11H2,1-3H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative small colonies RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance methyl N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfoxide N-(2,6-dimethylphenyl)-2-(methylsulfinyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Not in list C15H19N3O2S O=C(CS(C)=O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C15H19N3O2S/c1-12-6-4-7-13(2)15(12)18(14(19)10-21(3)20)11-17-9-5-8-16-17/h4-9H,10-11H2,1-3H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative large colonies RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance methyl N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfoxide N-(2,6-dimethylphenyl)-2-(methylsulfinyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Not in list C15H19N3O2S O=C(CS(C)=O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C15H19N3O2S/c1-12-6-4-7-13(2)15(12)18(14(19)10-21(3)20)11-17-9-5-8-16-17/h4-9H,10-11H2,1-3H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent no treatment without Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance methyl N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfoxide N-(2,6-dimethylphenyl)-2-(methylsulfinyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Not in list C15H19N3O2S O=C(CS(C)=O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C15H19N3O2S/c1-12-6-4-7-13(2)15(12)18(14(19)10-21(3)20)11-17-9-5-8-16-17/h4-9H,10-11H2,1-3H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent no treatment with Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance methyl N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfoxide N-(2,6-dimethylphenyl)-2-(methylsulfinyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Not in list C15H19N3O2S O=C(CS(C)=O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C15H19N3O2S/c1-12-6-4-7-13(2)15(12)18(14(19)10-21(3)20)11-17-9-5-8-16-17/h4-9H,10-11H2,1-3H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance methyl N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfoxide N-(2,6-dimethylphenyl)-2-(methylsulfinyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Not in list C15H19N3O2S O=C(CS(C)=O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C15H19N3O2S/c1-12-6-4-7-13(2)15(12)18(14(19)10-21(3)20)11-17-9-5-8-16-17/h4-9H,10-11H2,1-3H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance methyl N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfoxide N-(2,6-dimethylphenyl)-2-(methylsulfinyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Not in list C15H19N3O2S O=C(CS(C)=O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C15H19N3O2S/c1-12-6-4-7-13(2)15(12)18(14(19)10-21(3)20)11-17-9-5-8-16-17/h4-9H,10-11H2,1-3H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance methyl N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfoxide N-(2,6-dimethylphenyl)-2-(methylsulfinyl)-N-(1H-pyrazol-1-ylmethyl)acetamide Not in list C15H19N3O2S O=C(CS(C)=O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C15H19N3O2S/c1-12-6-4-7-13(2)15(12)18(14(19)10-21(3)20)11-17-9-5-8-16-17/h4-9H,10-11H2,1-3H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-[(2-hydroxycarbonyl-6-methyl)phenyl]-N-(1H-pyrazol-1-ylmethyl)oxalamide 2-[(carboxycarbonyl)(1H-pyrazol-1-ylmethyl)amino]-3-methylbenzoic acid Not in list C14H13N3O5 O=C(N(Cn1cccn1)c2c(C)cccc2C(=O)O)C(=O)O InChI=1S/C14H13N3O5/c1-9-4-2-5-10(13(19)20)11(9)17(12(18)14(21)22)8-16-7-3-6-15-16/h2-7H,8H2,1H3,(H,19,20)(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-[(2-hydroxycarbonyl-6-methyl)phenyl]-N-(1H-pyrazol-1-ylmethyl)oxalamide 2-[(carboxycarbonyl)(1H-pyrazol-1-ylmethyl)amino]-3-methylbenzoic acid Not in list C14H13N3O5 O=C(N(Cn1cccn1)c2c(C)cccc2C(=O)O)C(=O)O InChI=1S/C14H13N3O5/c1-9-4-2-5-10(13(19)20)11(9)17(12(18)14(21)22)8-16-7-3-6-15-16/h2-7H,8H2,1H3,(H,19,20)(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-[(2-hydroxycarbonyl-6-methyl)phenyl]-N-(1H-pyrazol-1-ylmethyl)oxalamide 2-[(carboxycarbonyl)(1H-pyrazol-1-ylmethyl)amino]-3-methylbenzoic acid Not in list C14H13N3O5 O=C(N(Cn1cccn1)c2c(C)cccc2C(=O)O)C(=O)O InChI=1S/C14H13N3O5/c1-9-4-2-5-10(13(19)20)11(9)17(12(18)14(21)22)8-16-7-3-6-15-16/h2-7H,8H2,1H3,(H,19,20)(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-[(2-hydroxycarbonyl-6-methyl)phenyl]-N-(1H-pyrazol-1-ylmethyl)oxalamide 2-[(carboxycarbonyl)(1H-pyrazol-1-ylmethyl)amino]-3-methylbenzoic acid Not in list C14H13N3O5 O=C(N(Cn1cccn1)c2c(C)cccc2C(=O)O)C(=O)O InChI=1S/C14H13N3O5/c1-9-4-2-5-10(13(19)20)11(9)17(12(18)14(21)22)8-16-7-3-6-15-16/h2-7H,8H2,1H3,(H,19,20)(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-[(2-hydroxycarbonyl-6-methyl)phenyl]-N-(1H-pyrazol-1-ylmethyl)oxalamide 2-[(carboxycarbonyl)(1H-pyrazol-1-ylmethyl)amino]-3-methylbenzoic acid Not in list C14H13N3O5 O=C(N(Cn1cccn1)c2c(C)cccc2C(=O)O)C(=O)O InChI=1S/C14H13N3O5/c1-9-4-2-5-10(13(19)20)11(9)17(12(18)14(21)22)8-16-7-3-6-15-16/h2-7H,8H2,1H3,(H,19,20)(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-[(2-hydroxycarbonyl-6-methyl)phenyl]-N-(1H-pyrazol-1-ylmethyl)oxalamide 2-[(carboxycarbonyl)(1H-pyrazol-1-ylmethyl)amino]-3-methylbenzoic acid Not in list C14H13N3O5 O=C(N(Cn1cccn1)c2c(C)cccc2C(=O)O)C(=O)O InChI=1S/C14H13N3O5/c1-9-4-2-5-10(13(19)20)11(9)17(12(18)14(21)22)8-16-7-3-6-15-16/h2-7H,8H2,1H3,(H,19,20)(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-[(2-hydroxycarbonyl-6-methyl)phenyl]-N-(1H-pyrazol-1-ylmethyl)oxalamide 2-[(carboxycarbonyl)(1H-pyrazol-1-ylmethyl)amino]-3-methylbenzoic acid Not in list C14H13N3O5 O=C(N(Cn1cccn1)c2c(C)cccc2C(=O)O)C(=O)O InChI=1S/C14H13N3O5/c1-9-4-2-5-10(13(19)20)11(9)17(12(18)14(21)22)8-16-7-3-6-15-16/h2-7H,8H2,1H3,(H,19,20)(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-[(2-hydroxycarbonyl-6-methyl)phenyl]-N-(1H-pyrazol-1-ylmethyl)oxalamide 2-[(carboxycarbonyl)(1H-pyrazol-1-ylmethyl)amino]-3-methylbenzoic acid Not in list C14H13N3O5 O=C(N(Cn1cccn1)c2c(C)cccc2C(=O)O)C(=O)O InChI=1S/C14H13N3O5/c1-9-4-2-5-10(13(19)20)11(9)17(12(18)14(21)22)8-16-7-3-6-15-16/h2-7H,8H2,1H3,(H,19,20)(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-[(2-hydroxycarbonyl-6-methyl)phenyl]-N-(1H-pyrazol-1-ylmethyl)oxalamide 2-[(carboxycarbonyl)(1H-pyrazol-1-ylmethyl)amino]-3-methylbenzoic acid Not in list C14H13N3O5 O=C(N(Cn1cccn1)c2c(C)cccc2C(=O)O)C(=O)O InChI=1S/C14H13N3O5/c1-9-4-2-5-10(13(19)20)11(9)17(12(18)14(21)22)8-16-7-3-6-15-16/h2-7H,8H2,1H3,(H,19,20)(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-[(2-hydroxycarbonyl-6-methyl)phenyl]-N-(1H-pyrazol-1-ylmethyl)oxalamide 2-[(carboxycarbonyl)(1H-pyrazol-1-ylmethyl)amino]-3-methylbenzoic acid Not in list C14H13N3O5 O=C(N(Cn1cccn1)c2c(C)cccc2C(=O)O)C(=O)O InChI=1S/C14H13N3O5/c1-9-4-2-5-10(13(19)20)11(9)17(12(18)14(21)22)8-16-7-3-6-15-16/h2-7H,8H2,1H3,(H,19,20)(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-[(2-hydroxycarbonyl-6-methyl)phenyl]-N-(1H-pyrazol-1-ylmethyl)oxalamide 2-[(carboxycarbonyl)(1H-pyrazol-1-ylmethyl)amino]-3-methylbenzoic acid Not in list C14H13N3O5 O=C(N(Cn1cccn1)c2c(C)cccc2C(=O)O)C(=O)O InChI=1S/C14H13N3O5/c1-9-4-2-5-10(13(19)20)11(9)17(12(18)14(21)22)8-16-7-3-6-15-16/h2-7H,8H2,1H3,(H,19,20)(H,21,22) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative small colonies RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-[(2-hydroxycarbonyl-6-methyl)phenyl]-N-(1H-pyrazol-1-ylmethyl)oxalamide 2-[(carboxycarbonyl)(1H-pyrazol-1-ylmethyl)amino]-3-methylbenzoic acid Not in list C14H13N3O5 O=C(N(Cn1cccn1)c2c(C)cccc2C(=O)O)C(=O)O InChI=1S/C14H13N3O5/c1-9-4-2-5-10(13(19)20)11(9)17(12(18)14(21)22)8-16-7-3-6-15-16/h2-7H,8H2,1H3,(H,19,20)(H,21,22) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative large colonies RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-[(2-hydroxycarbonyl-6-methyl)phenyl]-N-(1H-pyrazol-1-ylmethyl)oxalamide 2-[(carboxycarbonyl)(1H-pyrazol-1-ylmethyl)amino]-3-methylbenzoic acid Not in list C14H13N3O5 O=C(N(Cn1cccn1)c2c(C)cccc2C(=O)O)C(=O)O InChI=1S/C14H13N3O5/c1-9-4-2-5-10(13(19)20)11(9)17(12(18)14(21)22)8-16-7-3-6-15-16/h2-7H,8H2,1H3,(H,19,20)(H,21,22) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative small colonies RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-[(2-hydroxycarbonyl-6-methyl)phenyl]-N-(1H-pyrazol-1-ylmethyl)oxalamide 2-[(carboxycarbonyl)(1H-pyrazol-1-ylmethyl)amino]-3-methylbenzoic acid Not in list C14H13N3O5 O=C(N(Cn1cccn1)c2c(C)cccc2C(=O)O)C(=O)O InChI=1S/C14H13N3O5/c1-9-4-2-5-10(13(19)20)11(9)17(12(18)14(21)22)8-16-7-3-6-15-16/h2-7H,8H2,1H3,(H,19,20)(H,21,22) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative large colonies RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-[(2-hydroxycarbonyl-6-methyl)phenyl]-N-(1H-pyrazol-1-ylmethyl)oxalamide 2-[(carboxycarbonyl)(1H-pyrazol-1-ylmethyl)amino]-3-methylbenzoic acid Not in list C14H13N3O5 O=C(N(Cn1cccn1)c2c(C)cccc2C(=O)O)C(=O)O InChI=1S/C14H13N3O5/c1-9-4-2-5-10(13(19)20)11(9)17(12(18)14(21)22)8-16-7-3-6-15-16/h2-7H,8H2,1H3,(H,19,20)(H,21,22) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-[(2-hydroxycarbonyl-6-methyl)phenyl]-N-(1H-pyrazol-1-ylmethyl)oxalamide 2-[(carboxycarbonyl)(1H-pyrazol-1-ylmethyl)amino]-3-methylbenzoic acid Not in list C14H13N3O5 O=C(N(Cn1cccn1)c2c(C)cccc2C(=O)O)C(=O)O InChI=1S/C14H13N3O5/c1-9-4-2-5-10(13(19)20)11(9)17(12(18)14(21)22)8-16-7-3-6-15-16/h2-7H,8H2,1H3,(H,19,20)(H,21,22) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-[(2-hydroxycarbonyl-6-methyl)phenyl]-N-(1H-pyrazol-1-ylmethyl)oxalamide 2-[(carboxycarbonyl)(1H-pyrazol-1-ylmethyl)amino]-3-methylbenzoic acid Not in list C14H13N3O5 O=C(N(Cn1cccn1)c2c(C)cccc2C(=O)O)C(=O)O InChI=1S/C14H13N3O5/c1-9-4-2-5-10(13(19)20)11(9)17(12(18)14(21)22)8-16-7-3-6-15-16/h2-7H,8H2,1H3,(H,19,20)(H,21,22) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-[(2-hydroxycarbonyl-6-methyl)phenyl]-N-(1H-pyrazol-1-ylmethyl)oxalamide 2-[(carboxycarbonyl)(1H-pyrazol-1-ylmethyl)amino]-3-methylbenzoic acid Not in list C14H13N3O5 O=C(N(Cn1cccn1)c2c(C)cccc2C(=O)O)C(=O)O InChI=1S/C14H13N3O5/c1-9-4-2-5-10(13(19)20)11(9)17(12(18)14(21)22)8-16-7-3-6-15-16/h2-7H,8H2,1H3,(H,19,20)(H,21,22) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-[(2-hydroxycarbonyl-6-methyl)phenyl]-N-(1H-pyrazol-1-ylmethyl)oxalamide 2-[(carboxycarbonyl)(1H-pyrazol-1-ylmethyl)amino]-3-methylbenzoic acid Not in list C14H13N3O5 O=C(N(Cn1cccn1)c2c(C)cccc2C(=O)O)C(=O)O InChI=1S/C14H13N3O5/c1-9-4-2-5-10(13(19)20)11(9)17(12(18)14(21)22)8-16-7-3-6-15-16/h2-7H,8H2,1H3,(H,19,20)(H,21,22) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance N-[(2-hydroxycarbonyl-6-methyl)phenyl]-N-(1H-pyrazol-1-ylmethyl)oxalamide 2-[(carboxycarbonyl)(1H-pyrazol-1-ylmethyl)amino]-3-methylbenzoic acid Not in list C14H13N3O5 O=C(N(Cn1cccn1)c2c(C)cccc2C(=O)O)C(=O)O InChI=1S/C14H13N3O5/c1-9-4-2-5-10(13(19)20)11(9)17(12(18)14(21)22)8-16-7-3-6-15-16/h2-7H,8H2,1H3,(H,19,20)(H,21,22) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance 3-[N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl]-2-hydroxypropanoic acid 3-({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)-2-hydroxypropanoic acid Not in list C17H21N3O5S O=C(CS(=O)CC(O)C(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C17H21N3O5S/c1-12-5-3-6-13(2)16(12)20(11-19-8-4-7-18-19)15(22)10-26(25)9-14(21)17(23)24/h3-8,14,21H,9-11H2,1-2H3,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance 3-[N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl]-2-hydroxypropanoic acid 3-({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)-2-hydroxypropanoic acid Not in list C17H21N3O5S O=C(CS(=O)CC(O)C(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C17H21N3O5S/c1-12-5-3-6-13(2)16(12)20(11-19-8-4-7-18-19)15(22)10-26(25)9-14(21)17(23)24/h3-8,14,21H,9-11H2,1-2H3,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance 3-[N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl]-2-hydroxypropanoic acid 3-({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)-2-hydroxypropanoic acid Not in list C17H21N3O5S O=C(CS(=O)CC(O)C(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C17H21N3O5S/c1-12-5-3-6-13(2)16(12)20(11-19-8-4-7-18-19)15(22)10-26(25)9-14(21)17(23)24/h3-8,14,21H,9-11H2,1-2H3,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance 3-[N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl]-2-hydroxypropanoic acid 3-({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)-2-hydroxypropanoic acid Not in list C17H21N3O5S O=C(CS(=O)CC(O)C(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C17H21N3O5S/c1-12-5-3-6-13(2)16(12)20(11-19-8-4-7-18-19)15(22)10-26(25)9-14(21)17(23)24/h3-8,14,21H,9-11H2,1-2H3,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance 3-[N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl]-2-hydroxypropanoic acid 3-({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)-2-hydroxypropanoic acid Not in list C17H21N3O5S O=C(CS(=O)CC(O)C(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C17H21N3O5S/c1-12-5-3-6-13(2)16(12)20(11-19-8-4-7-18-19)15(22)10-26(25)9-14(21)17(23)24/h3-8,14,21H,9-11H2,1-2H3,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance 3-[N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl]-2-hydroxypropanoic acid 3-({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)-2-hydroxypropanoic acid Not in list C17H21N3O5S O=C(CS(=O)CC(O)C(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C17H21N3O5S/c1-12-5-3-6-13(2)16(12)20(11-19-8-4-7-18-19)15(22)10-26(25)9-14(21)17(23)24/h3-8,14,21H,9-11H2,1-2H3,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance 3-[N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl]-2-hydroxypropanoic acid 3-({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)-2-hydroxypropanoic acid Not in list C17H21N3O5S O=C(CS(=O)CC(O)C(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C17H21N3O5S/c1-12-5-3-6-13(2)16(12)20(11-19-8-4-7-18-19)15(22)10-26(25)9-14(21)17(23)24/h3-8,14,21H,9-11H2,1-2H3,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance 3-[N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl]-2-hydroxypropanoic acid 3-({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)-2-hydroxypropanoic acid Not in list C17H21N3O5S O=C(CS(=O)CC(O)C(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C17H21N3O5S/c1-12-5-3-6-13(2)16(12)20(11-19-8-4-7-18-19)15(22)10-26(25)9-14(21)17(23)24/h3-8,14,21H,9-11H2,1-2H3,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance 3-[N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl]-2-hydroxypropanoic acid 3-({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)-2-hydroxypropanoic acid Not in list C17H21N3O5S O=C(CS(=O)CC(O)C(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C17H21N3O5S/c1-12-5-3-6-13(2)16(12)20(11-19-8-4-7-18-19)15(22)10-26(25)9-14(21)17(23)24/h3-8,14,21H,9-11H2,1-2H3,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance 3-[N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl]-2-hydroxypropanoic acid 3-({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)-2-hydroxypropanoic acid Not in list C17H21N3O5S O=C(CS(=O)CC(O)C(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C17H21N3O5S/c1-12-5-3-6-13(2)16(12)20(11-19-8-4-7-18-19)15(22)10-26(25)9-14(21)17(23)24/h3-8,14,21H,9-11H2,1-2H3,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance 3-[N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl]-2-hydroxypropanoic acid 3-({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)-2-hydroxypropanoic acid Not in list C17H21N3O5S O=C(CS(=O)CC(O)C(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C17H21N3O5S/c1-12-5-3-6-13(2)16(12)20(11-19-8-4-7-18-19)15(22)10-26(25)9-14(21)17(23)24/h3-8,14,21H,9-11H2,1-2H3,(H,23,24) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative small colonies RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance 3-[N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl]-2-hydroxypropanoic acid 3-({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)-2-hydroxypropanoic acid Not in list C17H21N3O5S O=C(CS(=O)CC(O)C(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C17H21N3O5S/c1-12-5-3-6-13(2)16(12)20(11-19-8-4-7-18-19)15(22)10-26(25)9-14(21)17(23)24/h3-8,14,21H,9-11H2,1-2H3,(H,23,24) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative small colonies RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance 3-[N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl]-2-hydroxypropanoic acid 3-({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)-2-hydroxypropanoic acid Not in list C17H21N3O5S O=C(CS(=O)CC(O)C(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C17H21N3O5S/c1-12-5-3-6-13(2)16(12)20(11-19-8-4-7-18-19)15(22)10-26(25)9-14(21)17(23)24/h3-8,14,21H,9-11H2,1-2H3,(H,23,24) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative large colonies RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance 3-[N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl]-2-hydroxypropanoic acid 3-({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)-2-hydroxypropanoic acid Not in list C17H21N3O5S O=C(CS(=O)CC(O)C(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C17H21N3O5S/c1-12-5-3-6-13(2)16(12)20(11-19-8-4-7-18-19)15(22)10-26(25)9-14(21)17(23)24/h3-8,14,21H,9-11H2,1-2H3,(H,23,24) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative large colonies RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance 3-[N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl]-2-hydroxypropanoic acid 3-({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)-2-hydroxypropanoic acid Not in list C17H21N3O5S O=C(CS(=O)CC(O)C(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C17H21N3O5S/c1-12-5-3-6-13(2)16(12)20(11-19-8-4-7-18-19)15(22)10-26(25)9-14(21)17(23)24/h3-8,14,21H,9-11H2,1-2H3,(H,23,24) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Metazachlor 266-583-0 67129-08-2 single chemical entity Component is a metabolite of the substance 3-[N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl]-2-hydroxypropanoic acid 3-({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)-2-hydroxypropanoic acid Not in list C17H21N3O5S O=C(CS(=O)CC(O)C(=O)O)N(Cn1cccn1)c2c(C)cccc2C InChI=1S/C17H21N3O5S/c1-12-5-3-6-13(2)16(12)20(11-19-8-4-7-18-19)15(22)10-26(25)9-14(21)17(23)24/h3-8,14,21H,9-11H2,1-2H3,(H,23,24) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Metazachlor (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor 29Jul2008 2008 doi:10.2903/j.efsa.2008.145r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is identical to the substance Penconazole 266-275-6 66246-88-6 1-[2-(2,4-dichlorophenyl)pentyl]-1H-1,2,4-triazole Penconazole C13H15Cl2N3 ClC2=C(C=CC(Cl)=C2)C(CCC)CN1N=CN=C1 InChI=1S/C13H15Cl2N3/c1-2-3-10(7-18-9-16-8-17-18)12-5-4-11(14)6-13(12)15/h4-6,8-10H,2-3,7H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is identical to the substance Penconazole 266-275-6 66246-88-6 1-[2-(2,4-dichlorophenyl)pentyl]-1H-1,2,4-triazole Penconazole C13H15Cl2N3 ClC2=C(C=CC(Cl)=C2)C(CCC)CN1N=CN=C1 InChI=1S/C13H15Cl2N3/c1-2-3-10(7-18-9-16-8-17-18)12-5-4-11(14)6-13(12)15/h4-6,8-10H,2-3,7H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is identical to the substance Penconazole 266-275-6 66246-88-6 1-[2-(2,4-dichlorophenyl)pentyl]-1H-1,2,4-triazole Penconazole C13H15Cl2N3 ClC2=C(C=CC(Cl)=C2)C(CCC)CN1N=CN=C1 InChI=1S/C13H15Cl2N3/c1-2-3-10(7-18-9-16-8-17-18)12-5-4-11(14)6-13(12)15/h4-6,8-10H,2-3,7H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is identical to the substance Penconazole 266-275-6 66246-88-6 1-[2-(2,4-dichlorophenyl)pentyl]-1H-1,2,4-triazole Penconazole C13H15Cl2N3 ClC2=C(C=CC(Cl)=C2)C(CCC)CN1N=CN=C1 InChI=1S/C13H15Cl2N3/c1-2-3-10(7-18-9-16-8-17-18)12-5-4-11(14)6-13(12)15/h4-6,8-10H,2-3,7H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is identical to the substance Penconazole 266-275-6 66246-88-6 1-[2-(2,4-dichlorophenyl)pentyl]-1H-1,2,4-triazole Penconazole C13H15Cl2N3 ClC2=C(C=CC(Cl)=C2)C(CCC)CN1N=CN=C1 InChI=1S/C13H15Cl2N3/c1-2-3-10(7-18-9-16-8-17-18)12-5-4-11(14)6-13(12)15/h4-6,8-10H,2-3,7H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is identical to the substance Penconazole 266-275-6 66246-88-6 1-[2-(2,4-dichlorophenyl)pentyl]-1H-1,2,4-triazole Penconazole C13H15Cl2N3 ClC2=C(C=CC(Cl)=C2)C(CCC)CN1N=CN=C1 InChI=1S/C13H15Cl2N3/c1-2-3-10(7-18-9-16-8-17-18)12-5-4-11(14)6-13(12)15/h4-6,8-10H,2-3,7H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is identical to the substance Penconazole 266-275-6 66246-88-6 1-[2-(2,4-dichlorophenyl)pentyl]-1H-1,2,4-triazole Penconazole C13H15Cl2N3 ClC2=C(C=CC(Cl)=C2)C(CCC)CN1N=CN=C1 InChI=1S/C13H15Cl2N3/c1-2-3-10(7-18-9-16-8-17-18)12-5-4-11(14)6-13(12)15/h4-6,8-10H,2-3,7H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is identical to the substance Penconazole 266-275-6 66246-88-6 1-[2-(2,4-dichlorophenyl)pentyl]-1H-1,2,4-triazole Penconazole C13H15Cl2N3 ClC2=C(C=CC(Cl)=C2)C(CCC)CN1N=CN=C1 InChI=1S/C13H15Cl2N3/c1-2-3-10(7-18-9-16-8-17-18)12-5-4-11(14)6-13(12)15/h4-6,8-10H,2-3,7H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is identical to the substance Penconazole 266-275-6 66246-88-6 1-[2-(2,4-dichlorophenyl)pentyl]-1H-1,2,4-triazole Penconazole C13H15Cl2N3 ClC2=C(C=CC(Cl)=C2)C(CCC)CN1N=CN=C1 InChI=1S/C13H15Cl2N3/c1-2-3-10(7-18-9-16-8-17-18)12-5-4-11(14)6-13(12)15/h4-6,8-10H,2-3,7H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is identical to the substance Penconazole 266-275-6 66246-88-6 1-[2-(2,4-dichlorophenyl)pentyl]-1H-1,2,4-triazole Penconazole C13H15Cl2N3 ClC2=C(C=CC(Cl)=C2)C(CCC)CN1N=CN=C1 InChI=1S/C13H15Cl2N3/c1-2-3-10(7-18-9-16-8-17-18)12-5-4-11(14)6-13(12)15/h4-6,8-10H,2-3,7H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is identical to the substance Penconazole 266-275-6 66246-88-6 1-[2-(2,4-dichlorophenyl)pentyl]-1H-1,2,4-triazole Penconazole C13H15Cl2N3 ClC2=C(C=CC(Cl)=C2)C(CCC)CN1N=CN=C1 InChI=1S/C13H15Cl2N3/c1-2-3-10(7-18-9-16-8-17-18)12-5-4-11(14)6-13(12)15/h4-6,8-10H,2-3,7H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is identical to the substance Penconazole 266-275-6 66246-88-6 1-[2-(2,4-dichlorophenyl)pentyl]-1H-1,2,4-triazole Penconazole C13H15Cl2N3 ClC2=C(C=CC(Cl)=C2)C(CCC)CN1N=CN=C1 InChI=1S/C13H15Cl2N3/c1-2-3-10(7-18-9-16-8-17-18)12-5-4-11(14)6-13(12)15/h4-6,8-10H,2-3,7H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is identical to the substance Penconazole 266-275-6 66246-88-6 1-[2-(2,4-dichlorophenyl)pentyl]-1H-1,2,4-triazole Penconazole C13H15Cl2N3 ClC2=C(C=CC(Cl)=C2)C(CCC)CN1N=CN=C1 InChI=1S/C13H15Cl2N3/c1-2-3-10(7-18-9-16-8-17-18)12-5-4-11(14)6-13(12)15/h4-6,8-10H,2-3,7H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is identical to the substance Penconazole 266-275-6 66246-88-6 1-[2-(2,4-dichlorophenyl)pentyl]-1H-1,2,4-triazole Penconazole C13H15Cl2N3 ClC2=C(C=CC(Cl)=C2)C(CCC)CN1N=CN=C1 InChI=1S/C13H15Cl2N3/c1-2-3-10(7-18-9-16-8-17-18)12-5-4-11(14)6-13(12)15/h4-6,8-10H,2-3,7H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is identical to the substance Penconazole 266-275-6 66246-88-6 1-[2-(2,4-dichlorophenyl)pentyl]-1H-1,2,4-triazole Penconazole C13H15Cl2N3 ClC2=C(C=CC(Cl)=C2)C(CCC)CN1N=CN=C1 InChI=1S/C13H15Cl2N3/c1-2-3-10(7-18-9-16-8-17-18)12-5-4-11(14)6-13(12)15/h4-6,8-10H,2-3,7H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is identical to the substance Penconazole 266-275-6 66246-88-6 1-[2-(2,4-dichlorophenyl)pentyl]-1H-1,2,4-triazole Penconazole C13H15Cl2N3 ClC2=C(C=CC(Cl)=C2)C(CCC)CN1N=CN=C1 InChI=1S/C13H15Cl2N3/c1-2-3-10(7-18-9-16-8-17-18)12-5-4-11(14)6-13(12)15/h4-6,8-10H,2-3,7H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is identical to the substance Penconazole 266-275-6 66246-88-6 1-[2-(2,4-dichlorophenyl)pentyl]-1H-1,2,4-triazole Penconazole C13H15Cl2N3 ClC2=C(C=CC(Cl)=C2)C(CCC)CN1N=CN=C1 InChI=1S/C13H15Cl2N3/c1-2-3-10(7-18-9-16-8-17-18)12-5-4-11(14)6-13(12)15/h4-6,8-10H,2-3,7H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is identical to the substance Penconazole 266-275-6 66246-88-6 1-[2-(2,4-dichlorophenyl)pentyl]-1H-1,2,4-triazole Penconazole C13H15Cl2N3 ClC2=C(C=CC(Cl)=C2)C(CCC)CN1N=CN=C1 InChI=1S/C13H15Cl2N3/c1-2-3-10(7-18-9-16-8-17-18)12-5-4-11(14)6-13(12)15/h4-6,8-10H,2-3,7H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is identical to the substance Penconazole 266-275-6 66246-88-6 1-[2-(2,4-dichlorophenyl)pentyl]-1H-1,2,4-triazole Penconazole C13H15Cl2N3 ClC2=C(C=CC(Cl)=C2)C(CCC)CN1N=CN=C1 InChI=1S/C13H15Cl2N3/c1-2-3-10(7-18-9-16-8-17-18)12-5-4-11(14)6-13(12)15/h4-6,8-10H,2-3,7H2,1H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is identical to the substance Penconazole 266-275-6 66246-88-6 1-[2-(2,4-dichlorophenyl)pentyl]-1H-1,2,4-triazole Penconazole C13H15Cl2N3 ClC2=C(C=CC(Cl)=C2)C(CCC)CN1N=CN=C1 InChI=1S/C13H15Cl2N3/c1-2-3-10(7-18-9-16-8-17-18)12-5-4-11(14)6-13(12)15/h4-6,8-10H,2-3,7H2,1H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is identical to the substance Penconazole 266-275-6 66246-88-6 1-[2-(2,4-dichlorophenyl)pentyl]-1H-1,2,4-triazole Penconazole C13H15Cl2N3 ClC2=C(C=CC(Cl)=C2)C(CCC)CN1N=CN=C1 InChI=1S/C13H15Cl2N3/c1-2-3-10(7-18-9-16-8-17-18)12-5-4-11(14)6-13(12)15/h4-6,8-10H,2-3,7H2,1H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is identical to the substance Penconazole 266-275-6 66246-88-6 1-[2-(2,4-dichlorophenyl)pentyl]-1H-1,2,4-triazole Penconazole C13H15Cl2N3 ClC2=C(C=CC(Cl)=C2)C(CCC)CN1N=CN=C1 InChI=1S/C13H15Cl2N3/c1-2-3-10(7-18-9-16-8-17-18)12-5-4-11(14)6-13(12)15/h4-6,8-10H,2-3,7H2,1H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is identical to the substance Penconazole 266-275-6 66246-88-6 1-[2-(2,4-dichlorophenyl)pentyl]-1H-1,2,4-triazole Penconazole C13H15Cl2N3 ClC2=C(C=CC(Cl)=C2)C(CCC)CN1N=CN=C1 InChI=1S/C13H15Cl2N3/c1-2-3-10(7-18-9-16-8-17-18)12-5-4-11(14)6-13(12)15/h4-6,8-10H,2-3,7H2,1H3 organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle with Negative RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is identical to the substance Penconazole 266-275-6 66246-88-6 1-[2-(2,4-dichlorophenyl)pentyl]-1H-1,2,4-triazole Penconazole C13H15Cl2N3 ClC2=C(C=CC(Cl)=C2)C(CCC)CN1N=CN=C1 InChI=1S/C13H15Cl2N3/c1-2-3-10(7-18-9-16-8-17-18)12-5-4-11(14)6-13(12)15/h4-6,8-10H,2-3,7H2,1H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Penconazole 266-275-6 66246-88-6 single chemical entity Component is identical to the substance Penconazole 266-275-6 66246-88-6 1-[2-(2,4-dichlorophenyl)pentyl]-1H-1,2,4-triazole Penconazole C13H15Cl2N3 ClC2=C(C=CC(Cl)=C2)C(CCC)CN1N=CN=C1 InChI=1S/C13H15Cl2N3/c1-2-3-10(7-18-9-16-8-17-18)12-5-4-11(14)6-13(12)15/h4-6,8-10H,2-3,7H2,1H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Germany Penconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole 30Oct2008 2008 doi:10.2903/j.efsa.2008.175r
+Metconazole 125116-23-6 single chemical entity Component is identical to the substance Metconazole 125116-23-6 5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol Metconazole (sum of isomers) C17H22ClN3O CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium Metconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole. 22Feb2006 2006 doi:10.2903/j.efsa.2006.64r
+Metconazole 125116-23-6 single chemical entity Component is identical to the substance Metconazole 125116-23-6 5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol Metconazole (sum of isomers) C17H22ClN3O CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Belgium Metconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole. 22Feb2006 2006 doi:10.2903/j.efsa.2006.64r
+Metconazole 125116-23-6 single chemical entity Component is identical to the substance Metconazole 125116-23-6 5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol Metconazole (sum of isomers) C17H22ClN3O CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Belgium Metconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole. 22Feb2006 2006 doi:10.2903/j.efsa.2006.64r
+Metconazole 125116-23-6 single chemical entity Component is identical to the substance Metconazole 125116-23-6 5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol Metconazole (sum of isomers) C17H22ClN3O CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium Metconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole. 22Feb2006 2006 doi:10.2903/j.efsa.2006.64r
+Metconazole 125116-23-6 single chemical entity Component is identical to the substance Metconazole 125116-23-6 5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol Metconazole (sum of isomers) C17H22ClN3O CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium Metconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole. 22Feb2006 2006 doi:10.2903/j.efsa.2006.64r
+Metconazole 125116-23-6 single chemical entity Component is identical to the substance Metconazole 125116-23-6 5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol Metconazole (sum of isomers) C17H22ClN3O CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium Metconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole. 22Feb2006 2006 doi:10.2903/j.efsa.2006.64r
+Metconazole 125116-23-6 single chemical entity Component is identical to the substance Metconazole 125116-23-6 5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol Metconazole (sum of isomers) C17H22ClN3O CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium Metconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole. 22Feb2006 2006 doi:10.2903/j.efsa.2006.64r
+Metconazole 125116-23-6 single chemical entity Component is identical to the substance Metconazole 125116-23-6 5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol Metconazole (sum of isomers) C17H22ClN3O CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium Metconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole. 22Feb2006 2006 doi:10.2903/j.efsa.2006.64r
+Metconazole 125116-23-6 single chemical entity Component is identical to the substance Metconazole 125116-23-6 5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol Metconazole (sum of isomers) C17H22ClN3O CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium Metconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole. 22Feb2006 2006 doi:10.2903/j.efsa.2006.64r
+Metconazole 125116-23-6 single chemical entity Component is identical to the substance Metconazole 125116-23-6 5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol Metconazole (sum of isomers) C17H22ClN3O CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium Metconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole. 22Feb2006 2006 doi:10.2903/j.efsa.2006.64r
+Metconazole 125116-23-6 single chemical entity Component is identical to the substance Metconazole 125116-23-6 5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol Metconazole (sum of isomers) C17H22ClN3O CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Belgium Metconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole. 22Feb2006 2006 doi:10.2903/j.efsa.2006.64r
+Metconazole 125116-23-6 single chemical entity Component is identical to the substance Metconazole 125116-23-6 5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol Metconazole (sum of isomers) C17H22ClN3O CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Belgium Metconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole. 22Feb2006 2006 doi:10.2903/j.efsa.2006.64r
+Metconazole 125116-23-6 single chemical entity Component is identical to the substance Metconazole 125116-23-6 5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol Metconazole (sum of isomers) C17H22ClN3O CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium Metconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole. 22Feb2006 2006 doi:10.2903/j.efsa.2006.64r
+Metconazole 125116-23-6 single chemical entity Component is identical to the substance Metconazole 125116-23-6 5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol Metconazole (sum of isomers) C17H22ClN3O CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium Metconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole. 22Feb2006 2006 doi:10.2903/j.efsa.2006.64r
+Metconazole 125116-23-6 single chemical entity Component is identical to the substance Metconazole 125116-23-6 5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol Metconazole (sum of isomers) C17H22ClN3O CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium Metconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole. 22Feb2006 2006 doi:10.2903/j.efsa.2006.64r
+Metconazole 125116-23-6 single chemical entity Component is identical to the substance Metconazole 125116-23-6 5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol Metconazole (sum of isomers) C17H22ClN3O CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Belgium Metconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole. 22Feb2006 2006 doi:10.2903/j.efsa.2006.64r
+Metconazole 125116-23-6 single chemical entity Component is identical to the substance Metconazole 125116-23-6 5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol Metconazole (sum of isomers) C17H22ClN3O CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Belgium Metconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole. 22Feb2006 2006 doi:10.2903/j.efsa.2006.64r
+Metconazole 125116-23-6 single chemical entity Component is identical to the substance Metconazole 125116-23-6 5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol Metconazole (sum of isomers) C17H22ClN3O CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium Metconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole. 22Feb2006 2006 doi:10.2903/j.efsa.2006.64r
+Metconazole 125116-23-6 single chemical entity Component is identical to the substance Metconazole 125116-23-6 5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol Metconazole (sum of isomers) C17H22ClN3O CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium Metconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole. 22Feb2006 2006 doi:10.2903/j.efsa.2006.64r
+Metconazole 125116-23-6 single chemical entity Component is identical to the substance Metconazole 125116-23-6 5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol Metconazole (sum of isomers) C17H22ClN3O CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Belgium Metconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole. 22Feb2006 2006 doi:10.2903/j.efsa.2006.64r
+Metconazole 125116-23-6 single chemical entity Component is identical to the substance Metconazole 125116-23-6 5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol Metconazole (sum of isomers) C17H22ClN3O CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Belgium Metconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole. 22Feb2006 2006 doi:10.2903/j.efsa.2006.64r
+Metconazole 125116-23-6 single chemical entity Component is identical to the substance Metconazole 125116-23-6 5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol Metconazole (sum of isomers) C17H22ClN3O CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium Metconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole. 22Feb2006 2006 doi:10.2903/j.efsa.2006.64r
+Metconazole 125116-23-6 single chemical entity Component is identical to the substance Metconazole 125116-23-6 5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol Metconazole (sum of isomers) C17H22ClN3O CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium Metconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole. 22Feb2006 2006 doi:10.2903/j.efsa.2006.64r
+Metconazole 125116-23-6 single chemical entity Component is identical to the substance Metconazole 125116-23-6 5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol Metconazole (sum of isomers) C17H22ClN3O CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium Metconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole. 22Feb2006 2006 doi:10.2903/j.efsa.2006.64r
+Metconazole 125116-23-6 single chemical entity Component is identical to the substance Metconazole 125116-23-6 5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol Metconazole (sum of isomers) C17H22ClN3O CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Belgium Metconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole. 22Feb2006 2006 doi:10.2903/j.efsa.2006.64r
+Metconazole 125116-23-6 single chemical entity Component is identical to the substance Metconazole 125116-23-6 5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol Metconazole (sum of isomers) C17H22ClN3O CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Belgium Metconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole. 22Feb2006 2006 doi:10.2903/j.efsa.2006.64r
+Metconazole 125116-23-6 single chemical entity Component is identical to the substance Metconazole 125116-23-6 5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol Metconazole (sum of isomers) C17H22ClN3O CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Belgium Metconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole. 22Feb2006 2006 doi:10.2903/j.efsa.2006.64r
+Metconazole 125116-23-6 single chemical entity Component is identical to the substance Metconazole 125116-23-6 5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol Metconazole (sum of isomers) C17H22ClN3O CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Positive RMS: Belgium Metconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole. 22Feb2006 2006 doi:10.2903/j.efsa.2006.64r
+Metconazole 125116-23-6 single chemical entity Component is identical to the substance Metconazole 125116-23-6 5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol Metconazole (sum of isomers) C17H22ClN3O CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Belgium Metconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole. 22Feb2006 2006 doi:10.2903/j.efsa.2006.64r
+Metconazole 125116-23-6 single chemical entity Component is identical to the substance Metconazole 125116-23-6 5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol Metconazole (sum of isomers) C17H22ClN3O CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Belgium Metconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole. 22Feb2006 2006 doi:10.2903/j.efsa.2006.64r
+Metconazole 125116-23-6 single chemical entity Component is identical to the substance Metconazole 125116-23-6 5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol Metconazole (sum of isomers) C17H22ClN3O CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 48.0000000000 h yes not applicable Negative direct evidence-cytotoxicity RMS: Belgium Metconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole. 22Feb2006 2006 doi:10.2903/j.efsa.2006.64r
+Metconazole 125116-23-6 single chemical entity Component is identical to the substance Metconazole 125116-23-6 5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol Metconazole (sum of isomers) C17H22ClN3O CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 72.0000000000 h yes not applicable Negative direct evidence-cytotoxicity RMS: Belgium Metconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole. 22Feb2006 2006 doi:10.2903/j.efsa.2006.64r
+Metconazole 125116-23-6 single chemical entity Component is identical to the substance Metconazole 125116-23-6 5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol Metconazole (sum of isomers) C17H22ClN3O CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes not applicable Negative direct evidence-cytotoxicity RMS: Belgium Metconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole. 22Feb2006 2006 doi:10.2903/j.efsa.2006.64r
+Metconazole 125116-23-6 single chemical entity Component is identical to the substance Metconazole 125116-23-6 5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol Metconazole (sum of isomers) C17H22ClN3O CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 48.0000000000 h yes not applicable Negative direct evidence-cytotoxicity RMS: Belgium Metconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole. 22Feb2006 2006 doi:10.2903/j.efsa.2006.64r
+Metconazole 125116-23-6 single chemical entity Component is identical to the substance Metconazole 125116-23-6 5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol Metconazole (sum of isomers) C17H22ClN3O CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes not applicable Negative direct evidence-cytotoxicity RMS: Belgium Metconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole. 22Feb2006 2006 doi:10.2903/j.efsa.2006.64r
+Metconazole 125116-23-6 single chemical entity Component is identical to the substance Metconazole 125116-23-6 5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol Metconazole (sum of isomers) C17H22ClN3O CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Sprague-Dawley 3 Male oral: gavage 6.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Belgium Metconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole. 22Feb2006 2006 doi:10.2903/j.efsa.2006.64r
+Metconazole 125116-23-6 single chemical entity Component is identical to the substance Metconazole 125116-23-6 5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol Metconazole (sum of isomers) C17H22ClN3O CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Sprague-Dawley 3 Male oral: gavage 14.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Belgium Metconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole. 22Feb2006 2006 doi:10.2903/j.efsa.2006.64r
+Metconazole 125116-23-6 single chemical entity Component is identical to the substance Metconazole 125116-23-6 5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol Metconazole (sum of isomers) C17H22ClN3O CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Wistar 6 Male oral: gavage 13.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Belgium Metconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole. 22Feb2006 2006 doi:10.2903/j.efsa.2006.64r
+Metconazole 125116-23-6 single chemical entity Component is identical to the substance Metconazole 125116-23-6 5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol Metconazole (sum of isomers) C17H22ClN3O CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Wistar 6 Male oral: gavage 3.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Belgium Metconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole. 22Feb2006 2006 doi:10.2903/j.efsa.2006.64r
+Metconazole 125116-23-6 single chemical entity Component is identical to the substance Metconazole 125116-23-6 5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol Metconazole (sum of isomers) C17H22ClN3O CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes without Negative RMS: Belgium Metconazole (Addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole. 22Feb2006 2006 doi:10.2903/j.efsa.2006.64r
+Metconazole 125116-23-6 single chemical entity Component is identical to the substance Metconazole 125116-23-6 5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol Metconazole (sum of isomers) C17H22ClN3O CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes with Negative RMS: Belgium Metconazole (Addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole. 22Feb2006 2006 doi:10.2903/j.efsa.2006.64r
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Positive RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Positive RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Positive RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Positive RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Positive RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Positive RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Positive RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Positive RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 Not reported no data with Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 Not reported no data without Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 Not reported no data with Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Positive RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Positive RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Positive RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 Not reported no data without Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Positive RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 Not reported no data with Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Positive RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Positive RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Positive RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 Not reported no data without Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes with Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes without Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes with Ambiguous RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes without Ambiguous RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Negative no information RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative no information RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is a metabolite of the substance 4-methylsulfonyl-2-nitro benzoic acid 4-(methylsulfonyl)-2-nitrobenzoic acid Not in list C8H7NO6S O=S(C)(=O)c1cc(c(cc1)C(=O)O)N(=O)=O InChI=1S/C8H7NO6S/c1-16(14,15)5-2-3-6(8(10)11)7(4-5)9(12)13/h2-4H,1H3,(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is a metabolite of the substance 4-methylsulfonyl-2-nitro benzoic acid 4-(methylsulfonyl)-2-nitrobenzoic acid Not in list C8H7NO6S O=S(C)(=O)c1cc(c(cc1)C(=O)O)N(=O)=O InChI=1S/C8H7NO6S/c1-16(14,15)5-2-3-6(8(10)11)7(4-5)9(12)13/h2-4H,1H3,(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is a metabolite of the substance 4-methylsulfonyl-2-nitro benzoic acid 4-(methylsulfonyl)-2-nitrobenzoic acid Not in list C8H7NO6S O=S(C)(=O)c1cc(c(cc1)C(=O)O)N(=O)=O InChI=1S/C8H7NO6S/c1-16(14,15)5-2-3-6(8(10)11)7(4-5)9(12)13/h2-4H,1H3,(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is a metabolite of the substance 4-methylsulfonyl-2-nitro benzoic acid 4-(methylsulfonyl)-2-nitrobenzoic acid Not in list C8H7NO6S O=S(C)(=O)c1cc(c(cc1)C(=O)O)N(=O)=O InChI=1S/C8H7NO6S/c1-16(14,15)5-2-3-6(8(10)11)7(4-5)9(12)13/h2-4H,1H3,(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes without Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is a metabolite of the substance 4-methylsulfonyl-2-nitro benzoic acid 4-(methylsulfonyl)-2-nitrobenzoic acid Not in list C8H7NO6S O=S(C)(=O)c1cc(c(cc1)C(=O)O)N(=O)=O InChI=1S/C8H7NO6S/c1-16(14,15)5-2-3-6(8(10)11)7(4-5)9(12)13/h2-4H,1H3,(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is a metabolite of the substance 4-methylsulfonyl-2-nitro benzoic acid 4-(methylsulfonyl)-2-nitrobenzoic acid Not in list C8H7NO6S O=S(C)(=O)c1cc(c(cc1)C(=O)O)N(=O)=O InChI=1S/C8H7NO6S/c1-16(14,15)5-2-3-6(8(10)11)7(4-5)9(12)13/h2-4H,1H3,(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is a metabolite of the substance 4-methylsulfonyl-2-nitro benzoic acid 4-(methylsulfonyl)-2-nitrobenzoic acid Not in list C8H7NO6S O=S(C)(=O)c1cc(c(cc1)C(=O)O)N(=O)=O InChI=1S/C8H7NO6S/c1-16(14,15)5-2-3-6(8(10)11)7(4-5)9(12)13/h2-4H,1H3,(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is a metabolite of the substance 4-methylsulfonyl-2-nitro benzoic acid 4-(methylsulfonyl)-2-nitrobenzoic acid Not in list C8H7NO6S O=S(C)(=O)c1cc(c(cc1)C(=O)O)N(=O)=O InChI=1S/C8H7NO6S/c1-16(14,15)5-2-3-6(8(10)11)7(4-5)9(12)13/h2-4H,1H3,(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is a metabolite of the substance 4-methylsulfonyl-2-nitro benzoic acid 4-(methylsulfonyl)-2-nitrobenzoic acid Not in list C8H7NO6S O=S(C)(=O)c1cc(c(cc1)C(=O)O)N(=O)=O InChI=1S/C8H7NO6S/c1-16(14,15)5-2-3-6(8(10)11)7(4-5)9(12)13/h2-4H,1H3,(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is a metabolite of the substance 4-methylsulfonyl-2-nitro benzoic acid 4-(methylsulfonyl)-2-nitrobenzoic acid Not in list C8H7NO6S O=S(C)(=O)c1cc(c(cc1)C(=O)O)N(=O)=O InChI=1S/C8H7NO6S/c1-16(14,15)5-2-3-6(8(10)11)7(4-5)9(12)13/h2-4H,1H3,(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is a metabolite of the substance 4-methylsulfonyl-2-nitro benzoic acid 4-(methylsulfonyl)-2-nitrobenzoic acid Not in list C8H7NO6S O=S(C)(=O)c1cc(c(cc1)C(=O)O)N(=O)=O InChI=1S/C8H7NO6S/c1-16(14,15)5-2-3-6(8(10)11)7(4-5)9(12)13/h2-4H,1H3,(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is a metabolite of the substance 4-methylsulfonyl-2-nitro benzoic acid 4-(methylsulfonyl)-2-nitrobenzoic acid Not in list C8H7NO6S O=S(C)(=O)c1cc(c(cc1)C(=O)O)N(=O)=O InChI=1S/C8H7NO6S/c1-16(14,15)5-2-3-6(8(10)11)7(4-5)9(12)13/h2-4H,1H3,(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes with Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is a metabolite of the substance 2-amino-4-methylsulfonyl benzoic acid 2-amino-4-(methylsulfonyl)benzoic acid Not in list C8H9NO4S O=S(C)(=O)c1cc(N)c(cc1)C(=O)O InChI=1S/C8H9NO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,9H2,1H3,(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes with Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is a metabolite of the substance 2-amino-4-methylsulfonyl benzoic acid 2-amino-4-(methylsulfonyl)benzoic acid Not in list C8H9NO4S O=S(C)(=O)c1cc(N)c(cc1)C(=O)O InChI=1S/C8H9NO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,9H2,1H3,(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is a metabolite of the substance 2-amino-4-methylsulfonyl benzoic acid 2-amino-4-(methylsulfonyl)benzoic acid Not in list C8H9NO4S O=S(C)(=O)c1cc(N)c(cc1)C(=O)O InChI=1S/C8H9NO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,9H2,1H3,(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is a metabolite of the substance 2-amino-4-methylsulfonyl benzoic acid 2-amino-4-(methylsulfonyl)benzoic acid Not in list C8H9NO4S O=S(C)(=O)c1cc(N)c(cc1)C(=O)O InChI=1S/C8H9NO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,9H2,1H3,(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is a metabolite of the substance 2-amino-4-methylsulfonyl benzoic acid 2-amino-4-(methylsulfonyl)benzoic acid Not in list C8H9NO4S O=S(C)(=O)c1cc(N)c(cc1)C(=O)O InChI=1S/C8H9NO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,9H2,1H3,(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is a metabolite of the substance 2-amino-4-methylsulfonyl benzoic acid 2-amino-4-(methylsulfonyl)benzoic acid Not in list C8H9NO4S O=S(C)(=O)c1cc(N)c(cc1)C(=O)O InChI=1S/C8H9NO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,9H2,1H3,(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is a metabolite of the substance 2-amino-4-methylsulfonyl benzoic acid 2-amino-4-(methylsulfonyl)benzoic acid Not in list C8H9NO4S O=S(C)(=O)c1cc(N)c(cc1)C(=O)O InChI=1S/C8H9NO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,9H2,1H3,(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is a metabolite of the substance 2-amino-4-methylsulfonyl benzoic acid 2-amino-4-(methylsulfonyl)benzoic acid Not in list C8H9NO4S O=S(C)(=O)c1cc(N)c(cc1)C(=O)O InChI=1S/C8H9NO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,9H2,1H3,(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is a metabolite of the substance 2-amino-4-methylsulfonyl benzoic acid 2-amino-4-(methylsulfonyl)benzoic acid Not in list C8H9NO4S O=S(C)(=O)c1cc(N)c(cc1)C(=O)O InChI=1S/C8H9NO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,9H2,1H3,(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is a metabolite of the substance 2-amino-4-methylsulfonyl benzoic acid 2-amino-4-(methylsulfonyl)benzoic acid Not in list C8H9NO4S O=S(C)(=O)c1cc(N)c(cc1)C(=O)O InChI=1S/C8H9NO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,9H2,1H3,(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is a metabolite of the substance 2-amino-4-methylsulfonyl benzoic acid 2-amino-4-(methylsulfonyl)benzoic acid Not in list C8H9NO4S O=S(C)(=O)c1cc(N)c(cc1)C(=O)O InChI=1S/C8H9NO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,9H2,1H3,(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is a metabolite of the substance 2-amino-4-methylsulfonyl benzoic acid 2-amino-4-(methylsulfonyl)benzoic acid Not in list C8H9NO4S O=S(C)(=O)c1cc(N)c(cc1)C(=O)O InChI=1S/C8H9NO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,9H2,1H3,(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes without Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is a metabolite of the substance 4-methylsulfonyl-2-nitro benzoic acid 4-(methylsulfonyl)-2-nitrobenzoic acid Not in list C8H7NO6S O=S(C)(=O)c1cc(c(cc1)C(=O)O)N(=O)=O InChI=1S/C8H7NO6S/c1-16(14,15)5-2-3-6(8(10)11)7(4-5)9(12)13/h2-4H,1H3,(H,10,11) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes without Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is a metabolite of the substance 4-methylsulfonyl-2-nitro benzoic acid 4-(methylsulfonyl)-2-nitrobenzoic acid Not in list C8H7NO6S O=S(C)(=O)c1cc(c(cc1)C(=O)O)N(=O)=O InChI=1S/C8H7NO6S/c1-16(14,15)5-2-3-6(8(10)11)7(4-5)9(12)13/h2-4H,1H3,(H,10,11) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes with Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is a metabolite of the substance 4-methylsulfonyl-2-nitro benzoic acid 4-(methylsulfonyl)-2-nitrobenzoic acid Not in list C8H7NO6S O=S(C)(=O)c1cc(c(cc1)C(=O)O)N(=O)=O InChI=1S/C8H7NO6S/c1-16(14,15)5-2-3-6(8(10)11)7(4-5)9(12)13/h2-4H,1H3,(H,10,11) organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo Equivalent or similar to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) Yes Acceptable Rat (as animal) Alpk:APf SD Rat 5 Male oral: gavage 16.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is a metabolite of the substance 4-methylsulfonyl-2-nitro benzoic acid 4-(methylsulfonyl)-2-nitrobenzoic acid Not in list C8H7NO6S O=S(C)(=O)c1cc(c(cc1)C(=O)O)N(=O)=O InChI=1S/C8H7NO6S/c1-16(14,15)5-2-3-6(8(10)11)7(4-5)9(12)13/h2-4H,1H3,(H,10,11) organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo Equivalent or similar to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) Yes Acceptable Rat (as animal) Alpk:APf SD Rat 5 Male oral: gavage 6.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is a metabolite of the substance 4-methylsulfonyl-2-nitro benzoic acid 4-(methylsulfonyl)-2-nitrobenzoic acid Not in list C8H7NO6S O=S(C)(=O)c1cc(c(cc1)C(=O)O)N(=O)=O InChI=1S/C8H7NO6S/c1-16(14,15)5-2-3-6(8(10)11)7(4-5)9(12)13/h2-4H,1H3,(H,10,11) organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo Equivalent or similar to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) Yes Acceptable Rat (as animal) Alpk:APf SD Rat 5 Male oral: gavage 2.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is a metabolite of the substance 4-methylsulfonyl-2-nitro benzoic acid 4-(methylsulfonyl)-2-nitrobenzoic acid Not in list C8H7NO6S O=S(C)(=O)c1cc(c(cc1)C(=O)O)N(=O)=O InChI=1S/C8H7NO6S/c1-16(14,15)5-2-3-6(8(10)11)7(4-5)9(12)13/h2-4H,1H3,(H,10,11) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable Rat (as animal) Alpk:APf SD Rat 10 Male oral: gavage 48.0000000000 h yes not applicable Negative no evidence RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is a metabolite of the substance 4-methylsulfonyl-2-nitro benzoic acid 4-(methylsulfonyl)-2-nitrobenzoic acid Not in list C8H7NO6S O=S(C)(=O)c1cc(c(cc1)C(=O)O)N(=O)=O InChI=1S/C8H7NO6S/c1-16(14,15)5-2-3-6(8(10)11)7(4-5)9(12)13/h2-4H,1H3,(H,10,11) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable Rat (as animal) Alpk:APf SD Rat 10 Male oral: gavage 28.0000000000 h yes not applicable Negative no evidence RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is a metabolite of the substance 2-amino-4-methylsulfonyl benzoic acid 2-amino-4-(methylsulfonyl)benzoic acid Not in list C8H9NO4S O=S(C)(=O)c1cc(N)c(cc1)C(=O)O InChI=1S/C8H9NO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,9H2,1H3,(H,10,11) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes without Positive RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is a metabolite of the substance 2-amino-4-methylsulfonyl benzoic acid 2-amino-4-(methylsulfonyl)benzoic acid Not in list C8H9NO4S O=S(C)(=O)c1cc(N)c(cc1)C(=O)O InChI=1S/C8H9NO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,9H2,1H3,(H,10,11) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes with Positive RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is identical to the substance Metam-sodium 205-293-0 137-42-8 Sodium;N-methylcarbamodithioate Not in list C2H4NNaS2 CNC(=S)[S-].[Na+] InChI=1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is identical to the substance Metam-sodium 205-293-0 137-42-8 Sodium;N-methylcarbamodithioate Not in list C2H4NNaS2 CNC(=S)[S-].[Na+] InChI=1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA92 Not reported yes, concurrent vehicle with Negative RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is identical to the substance Metam-sodium 205-293-0 137-42-8 Sodium;N-methylcarbamodithioate Not in list C2H4NNaS2 CNC(=S)[S-].[Na+] InChI=1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is identical to the substance Metam-sodium 205-293-0 137-42-8 Sodium;N-methylcarbamodithioate Not in list C2H4NNaS2 CNC(=S)[S-].[Na+] InChI=1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is identical to the substance Metam-sodium 205-293-0 137-42-8 Sodium;N-methylcarbamodithioate Not in list C2H4NNaS2 CNC(=S)[S-].[Na+] InChI=1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is identical to the substance Metam-sodium 205-293-0 137-42-8 Sodium;N-methylcarbamodithioate Not in list C2H4NNaS2 CNC(=S)[S-].[Na+] InChI=1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA92 Not reported yes, concurrent vehicle without Negative RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is identical to the substance Metam-sodium 205-293-0 137-42-8 Sodium;N-methylcarbamodithioate Not in list C2H4NNaS2 CNC(=S)[S-].[Na+] InChI=1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is identical to the substance Metam-sodium 205-293-0 137-42-8 Sodium;N-methylcarbamodithioate Not in list C2H4NNaS2 CNC(=S)[S-].[Na+] InChI=1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is identical to the substance Metam-sodium 205-293-0 137-42-8 Sodium;N-methylcarbamodithioate Not in list C2H4NNaS2 CNC(=S)[S-].[Na+] InChI=1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is identical to the substance Metam-sodium 205-293-0 137-42-8 Sodium;N-methylcarbamodithioate Not in list C2H4NNaS2 CNC(=S)[S-].[Na+] InChI=1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is identical to the substance Metam-sodium 205-293-0 137-42-8 Sodium;N-methylcarbamodithioate Not in list C2H4NNaS2 CNC(=S)[S-].[Na+] InChI=1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is identical to the substance Metam-sodium 205-293-0 137-42-8 Sodium;N-methylcarbamodithioate Not in list C2H4NNaS2 CNC(=S)[S-].[Na+] InChI=1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is identical to the substance Metam-sodium 205-293-0 137-42-8 Sodium;N-methylcarbamodithioate Not in list C2H4NNaS2 CNC(=S)[S-].[Na+] InChI=1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes without Ambiguous RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is identical to the substance Metam-sodium 205-293-0 137-42-8 Sodium;N-methylcarbamodithioate Not in list C2H4NNaS2 CNC(=S)[S-].[Na+] InChI=1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes with Ambiguous RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is identical to the substance Metam-sodium 205-293-0 137-42-8 Sodium;N-methylcarbamodithioate Not in list C2H4NNaS2 CNC(=S)[S-].[Na+] InChI=1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes without Negative RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is identical to the substance Metam-sodium 205-293-0 137-42-8 Sodium;N-methylcarbamodithioate Not in list C2H4NNaS2 CNC(=S)[S-].[Na+] InChI=1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes with Negative RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is identical to the substance Metam-sodium 205-293-0 137-42-8 Sodium;N-methylcarbamodithioate Not in list C2H4NNaS2 CNC(=S)[S-].[Na+] InChI=1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Ambiguous RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is identical to the substance Metam-sodium 205-293-0 137-42-8 Sodium;N-methylcarbamodithioate Not in list C2H4NNaS2 CNC(=S)[S-].[Na+] InChI=1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Ambiguous RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is identical to the substance Metam-sodium 205-293-0 137-42-8 Sodium;N-methylcarbamodithioate Not in list C2H4NNaS2 CNC(=S)[S-].[Na+] InChI=1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is identical to the substance Metam-sodium 205-293-0 137-42-8 Sodium;N-methylcarbamodithioate Not in list C2H4NNaS2 CNC(=S)[S-].[Na+] InChI=1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes, concurrent no treatment with Negative RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is identical to the substance Metam-sodium 205-293-0 137-42-8 Sodium;N-methylcarbamodithioate Not in list C2H4NNaS2 CNC(=S)[S-].[Na+] InChI=1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes, concurrent no treatment with Negative RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is identical to the substance Metam-sodium 205-293-0 137-42-8 Sodium;N-methylcarbamodithioate Not in list C2H4NNaS2 CNC(=S)[S-].[Na+] InChI=1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes, concurrent no treatment without Negative RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is identical to the substance Metam-sodium 205-293-0 137-42-8 Sodium;N-methylcarbamodithioate Not in list C2H4NNaS2 CNC(=S)[S-].[Na+] InChI=1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes, concurrent no treatment without Negative RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is identical to the substance Metam-sodium 205-293-0 137-42-8 Sodium;N-methylcarbamodithioate Not in list C2H4NNaS2 CNC(=S)[S-].[Na+] InChI=1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female oral: unspecified 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is identical to the substance Metam-sodium 205-293-0 137-42-8 Sodium;N-methylcarbamodithioate Not in list C2H4NNaS2 CNC(=S)[S-].[Na+] InChI=1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is identical to the substance Metam-sodium 205-293-0 137-42-8 Sodium;N-methylcarbamodithioate Not in list C2H4NNaS2 CNC(=S)[S-].[Na+] InChI=1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Hamster (as animal) Chinese 10 Male/Female oral: unspecified 6.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is identical to the substance Metam-sodium 205-293-0 137-42-8 Sodium;N-methylcarbamodithioate Not in list C2H4NNaS2 CNC(=S)[S-].[Na+] InChI=1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Hamster (as animal) Chinese 10 Male/Female oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is identical to the substance Metam-sodium 205-293-0 137-42-8 Sodium;N-methylcarbamodithioate Not in list C2H4NNaS2 CNC(=S)[S-].[Na+] InChI=1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Hamster (as animal) Chinese 10 Male/Female oral: unspecified 48.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes with Negative RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes without Negative RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes without Negative RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes with Negative RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes without Negative RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes with Negative RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 30 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity$indirect evidence-systemic toxicity RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 30 Male/Female oral: gavage 72.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity$indirect evidence-systemic toxicity RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 30 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity$indirect evidence-systemic toxicity RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation other in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) Not reported 3 Male oral: gavage no data not applicable Positive RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) Not reported no data with Positive RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian cell micronucleus test in vitro Equivalent or similar to OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test) No data Acceptable Human (as organism) Hep G2 human cell line Not reported no data no data Positive RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is identical to the substance Metam-sodium 205-293-0 137-42-8 Sodium;N-methylcarbamodithioate Not in list C2H4NNaS2 CNC(=S)[S-].[Na+] InChI=1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Positive RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is identical to the substance Metam-sodium 205-293-0 137-42-8 Sodium;N-methylcarbamodithioate Not in list C2H4NNaS2 CNC(=S)[S-].[Na+] InChI=1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Positive RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) Not reported no data without Positive RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is identical to the substance Metam-sodium 205-293-0 137-42-8 Sodium;N-methylcarbamodithioate Not in list C2H4NNaS2 CNC(=S)[S-].[Na+] InChI=1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Positive RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vitro No guideline available Not reported Not applicable Acceptable Human (as organism) Hep G2 human cell line Not reported yes no data Positive RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) Not reported no data without Positive RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is identical to the substance Metam-sodium 205-293-0 137-42-8 Sodium;N-methylcarbamodithioate Not in list C2H4NNaS2 CNC(=S)[S-].[Na+] InChI=1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Positive RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is a metabolite of the substance Methyl isothiocyanate 209-132-5 556-61-6 Methylimino(sulfanylidene)methane Methyl-Isothiocyanate C2H3NS CN=C=S InChI=1S/C2H3NS/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) Not reported no data with Positive RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is a metabolite of the substance Methyl isocyanate 210-866-3 624-83-9 methylimino(oxo)methane Not in list C2H3NO CN=C=O InChI=1S/C2H3NO/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) No data Acceptable Rat (as animal) Wistar Male inhalation: unspecified 8.0000000000 min no data not applicable Negative RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is a metabolite of the substance Methyl isocyanate 210-866-3 624-83-9 methylimino(oxo)methane Not in list C2H3NO CN=C=O InChI=1S/C2H3NO/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro No guideline followed Not reported Not applicable Acceptable House mouse (as animal) Not reported no no data Positive RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is a metabolite of the substance Methyl isocyanate 210-866-3 624-83-9 methylimino(oxo)methane Not in list C2H3NO CN=C=O InChI=1S/C2H3NO/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is a metabolite of the substance Methyl isocyanate 210-866-3 624-83-9 methylimino(oxo)methane Not in list C2H3NO CN=C=O InChI=1S/C2H3NO/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is a metabolite of the substance Methyl isocyanate 210-866-3 624-83-9 methylimino(oxo)methane Not in list C2H3NO CN=C=O InChI=1S/C2H3NO/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is a metabolite of the substance Methyl isocyanate 210-866-3 624-83-9 methylimino(oxo)methane Not in list C2H3NO CN=C=O InChI=1S/C2H3NO/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle with Negative RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is a metabolite of the substance Methyl isocyanate 210-866-3 624-83-9 methylimino(oxo)methane Not in list C2H3NO CN=C=O InChI=1S/C2H3NO/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No data Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Positive RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is a metabolite of the substance Methyl isocyanate 210-866-3 624-83-9 methylimino(oxo)methane Not in list C2H3NO CN=C=O InChI=1S/C2H3NO/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) B6C3F1 Male inhalation: unspecified 2.0000000000 h yes not applicable Negative RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is a metabolite of the substance Methyl isocyanate 210-866-3 624-83-9 methylimino(oxo)methane Not in list C2H3NO CN=C=O InChI=1S/C2H3NO/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle without Negative RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is a metabolite of the substance Methyl isocyanate 210-866-3 624-83-9 methylimino(oxo)methane Not in list C2H3NO CN=C=O InChI=1S/C2H3NO/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI genome mutation Drosophila SLRL test in vivo Equivalent or similar to OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster) No data Acceptable Drosophila melanogaster (as animal) Not reported Male inhalation: aerosol yes, concurrent vehicle not applicable Negative RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is a metabolite of the substance Methyl isocyanate 210-866-3 624-83-9 methylimino(oxo)methane Not in list C2H3NO CN=C=O InChI=1S/C2H3NO/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable House mouse (as animal) B6C3F1 Male inhalation: unspecified 2.0000000000 h yes not applicable Negative RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is a metabolite of the substance Methyl isocyanate 210-866-3 624-83-9 methylimino(oxo)methane Not in list C2H3NO CN=C=O InChI=1S/C2H3NO/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No data Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Positive no information RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is a metabolite of the substance Methyl isocyanate 210-866-3 624-83-9 methylimino(oxo)methane Not in list C2H3NO CN=C=O InChI=1S/C2H3NO/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No data Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Positive RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is a metabolite of the substance Methyl isocyanate 210-866-3 624-83-9 methylimino(oxo)methane Not in list C2H3NO CN=C=O InChI=1S/C2H3NO/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro No guideline followed Not reported Not applicable Acceptable House mouse (as animal) lymphocytes Not reported no no data Negative RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is a metabolite of the substance Methyl isocyanate 210-866-3 624-83-9 methylimino(oxo)methane Not in list C2H3NO CN=C=O InChI=1S/C2H3NO/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is a metabolite of the substance Methyl isocyanate 210-866-3 624-83-9 methylimino(oxo)methane Not in list C2H3NO CN=C=O InChI=1S/C2H3NO/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is a metabolite of the substance Methyl isocyanate 210-866-3 624-83-9 methylimino(oxo)methane Not in list C2H3NO CN=C=O InChI=1S/C2H3NO/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) B6C3F1 Male/Female inhalation: unspecified 4.0000000000 D yes not applicable Positive RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is a metabolite of the substance Methyl isocyanate 210-866-3 624-83-9 methylimino(oxo)methane Not in list C2H3NO CN=C=O InChI=1S/C2H3NO/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No data Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Positive RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is a metabolite of the substance Methyl isocyanate 210-866-3 624-83-9 methylimino(oxo)methane Not in list C2H3NO CN=C=O InChI=1S/C2H3NO/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is a metabolite of the substance Methyl isocyanate 210-866-3 624-83-9 methylimino(oxo)methane Not in list C2H3NO CN=C=O InChI=1S/C2H3NO/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No data Acceptable House mouse (as animal) B6C3F1 Male inhalation: unspecified 2.0000000000 h yes not applicable Negative RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is a metabolite of the substance Methyl isocyanate 210-866-3 624-83-9 methylimino(oxo)methane Not in list C2H3NO CN=C=O InChI=1S/C2H3NO/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI genome mutation Drosophila SLRL test in vivo Equivalent or similar to OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster) No data Acceptable Drosophila melanogaster (as animal) Not reported Male oral: feed yes, concurrent vehicle not applicable Negative RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is a metabolite of the substance Methyl isocyanate 210-866-3 624-83-9 methylimino(oxo)methane Not in list C2H3NO CN=C=O InChI=1S/C2H3NO/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No data Acceptable House mouse (as animal) B6C3F1 Male/Female inhalation: unspecified 4.0000000000 D yes not applicable Positive RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is a metabolite of the substance Methyl isocyanate 210-866-3 624-83-9 methylimino(oxo)methane Not in list C2H3NO CN=C=O InChI=1S/C2H3NO/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is a metabolite of the substance Methyl isocyanate 210-866-3 624-83-9 methylimino(oxo)methane Not in list C2H3NO CN=C=O InChI=1S/C2H3NO/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI genome mutation Drosophila SLRL test in vivo Equivalent or similar to OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster) No data Acceptable Drosophila melanogaster (as animal) Not reported Male other yes, concurrent vehicle not applicable Negative RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is a metabolite of the substance Methyl isocyanate 210-866-3 624-83-9 methylimino(oxo)methane Not in list C2H3NO CN=C=O InChI=1S/C2H3NO/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is a metabolite of the substance Methyl isocyanate 210-866-3 624-83-9 methylimino(oxo)methane Not in list C2H3NO CN=C=O InChI=1S/C2H3NO/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable House mouse (as animal) B6C3F1 Male/Female inhalation: unspecified 4.0000000000 D yes not applicable Positive RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Metam-sodium 205-293-0 137-42-8 single chemical entity Component is a metabolite of the substance Methyl isocyanate 210-866-3 624-83-9 methylimino(oxo)methane Not in list C2H3NO CN=C=O InChI=1S/C2H3NO/c1-3-2-4/h1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No data Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Positive RMS: Belgium Metam-sodium (Updated DAR Re-submission) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metam 12Sep2011 2011 doi:10.2903/j.efsa.2011.2334
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is identical to the substance Napropamide 239-333-3 15299-99-7 N,N-diethyl-2-(1-naphthyloxy)propanamide Napropamide C17H21NO2 CCN(CC)C(=O)C(C)Oc2cccc1ccccc12 InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Denmark Napropamide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is identical to the substance Napropamide 239-333-3 15299-99-7 N,N-diethyl-2-(1-naphthyloxy)propanamide Napropamide C17H21NO2 CCN(CC)C(=O)C(C)Oc2cccc1ccccc12 InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Denmark Napropamide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is identical to the substance Napropamide 239-333-3 15299-99-7 N,N-diethyl-2-(1-naphthyloxy)propanamide Napropamide C17H21NO2 CCN(CC)C(=O)C(C)Oc2cccc1ccccc12 InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Denmark Napropamide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is identical to the substance Napropamide 239-333-3 15299-99-7 N,N-diethyl-2-(1-naphthyloxy)propanamide Napropamide C17H21NO2 CCN(CC)C(=O)C(C)Oc2cccc1ccccc12 InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Denmark Napropamide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is identical to the substance Napropamide 239-333-3 15299-99-7 N,N-diethyl-2-(1-naphthyloxy)propanamide Napropamide C17H21NO2 CCN(CC)C(=O)C(C)Oc2cccc1ccccc12 InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3 organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes, concurrent vehicle no data Negative RMS: Denmark Napropamide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is identical to the substance Napropamide 239-333-3 15299-99-7 N,N-diethyl-2-(1-naphthyloxy)propanamide Napropamide C17H21NO2 CCN(CC)C(=O)C(C)Oc2cccc1ccccc12 InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Denmark Napropamide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is identical to the substance Napropamide 239-333-3 15299-99-7 N,N-diethyl-2-(1-naphthyloxy)propanamide Napropamide C17H21NO2 CCN(CC)C(=O)C(C)Oc2cccc1ccccc12 InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Denmark Napropamide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is identical to the substance Napropamide 239-333-3 15299-99-7 N,N-diethyl-2-(1-naphthyloxy)propanamide Napropamide C17H21NO2 CCN(CC)C(=O)C(C)Oc2cccc1ccccc12 InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3 organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes, concurrent vehicle no data Negative RMS: Denmark Napropamide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is identical to the substance Napropamide 239-333-3 15299-99-7 N,N-diethyl-2-(1-naphthyloxy)propanamide Napropamide C17H21NO2 CCN(CC)C(=O)C(C)Oc2cccc1ccccc12 InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3 organic compound Other Other gene mutation other in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) ICR 6 Male oral: gavage 27.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Denmark Napropamide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is identical to the substance Napropamide 239-333-3 15299-99-7 N,N-diethyl-2-(1-naphthyloxy)propanamide Napropamide C17H21NO2 CCN(CC)C(=O)C(C)Oc2cccc1ccccc12 InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Denmark Napropamide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is identical to the substance Napropamide 239-333-3 15299-99-7 N,N-diethyl-2-(1-naphthyloxy)propanamide Napropamide C17H21NO2 CCN(CC)C(=O)C(C)Oc2cccc1ccccc12 InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Denmark Napropamide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is identical to the substance Napropamide 239-333-3 15299-99-7 N,N-diethyl-2-(1-naphthyloxy)propanamide Napropamide C17H21NO2 CCN(CC)C(=O)C(C)Oc2cccc1ccccc12 InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Denmark Napropamide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is identical to the substance Napropamide 239-333-3 15299-99-7 N,N-diethyl-2-(1-naphthyloxy)propanamide Napropamide C17H21NO2 CCN(CC)C(=O)C(C)Oc2cccc1ccccc12 InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Denmark Napropamide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is identical to the substance Napropamide 239-333-3 15299-99-7 N,N-diethyl-2-(1-naphthyloxy)propanamide Napropamide C17H21NO2 CCN(CC)C(=O)C(C)Oc2cccc1ccccc12 InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Denmark Napropamide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is identical to the substance Napropamide 239-333-3 15299-99-7 N,N-diethyl-2-(1-naphthyloxy)propanamide Napropamide C17H21NO2 CCN(CC)C(=O)C(C)Oc2cccc1ccccc12 InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Denmark Napropamide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is identical to the substance Napropamide 239-333-3 15299-99-7 N,N-diethyl-2-(1-naphthyloxy)propanamide Napropamide C17H21NO2 CCN(CC)C(=O)C(C)Oc2cccc1ccccc12 InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Denmark Napropamide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is identical to the substance Napropamide 239-333-3 15299-99-7 N,N-diethyl-2-(1-naphthyloxy)propanamide Napropamide C17H21NO2 CCN(CC)C(=O)C(C)Oc2cccc1ccccc12 InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Denmark Napropamide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is identical to the substance Napropamide 239-333-3 15299-99-7 N,N-diethyl-2-(1-naphthyloxy)propanamide Napropamide C17H21NO2 CCN(CC)C(=O)C(C)Oc2cccc1ccccc12 InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Denmark Napropamide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is identical to the substance Napropamide 239-333-3 15299-99-7 N,N-diethyl-2-(1-naphthyloxy)propanamide Napropamide C17H21NO2 CCN(CC)C(=O)C(C)Oc2cccc1ccccc12 InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Denmark Napropamide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is identical to the substance Napropamide 239-333-3 15299-99-7 N,N-diethyl-2-(1-naphthyloxy)propanamide Napropamide C17H21NO2 CCN(CC)C(=O)C(C)Oc2cccc1ccccc12 InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Denmark Napropamide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is identical to the substance Napropamide 239-333-3 15299-99-7 N,N-diethyl-2-(1-naphthyloxy)propanamide Napropamide C17H21NO2 CCN(CC)C(=O)C(C)Oc2cccc1ccccc12 InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Denmark Napropamide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is identical to the substance Napropamide 239-333-3 15299-99-7 N,N-diethyl-2-(1-naphthyloxy)propanamide Napropamide C17H21NO2 CCN(CC)C(=O)C(C)Oc2cccc1ccccc12 InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Denmark Napropamide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is identical to the substance Napropamide 239-333-3 15299-99-7 N,N-diethyl-2-(1-naphthyloxy)propanamide Napropamide C17H21NO2 CCN(CC)C(=O)C(C)Oc2cccc1ccccc12 InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Denmark Napropamide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is identical to the substance Napropamide 239-333-3 15299-99-7 N,N-diethyl-2-(1-naphthyloxy)propanamide Napropamide C17H21NO2 CCN(CC)C(=O)C(C)Oc2cccc1ccccc12 InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Positive no information RMS: Denmark Napropamide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is identical to the substance Napropamide 239-333-3 15299-99-7 N,N-diethyl-2-(1-naphthyloxy)propanamide Napropamide C17H21NO2 CCN(CC)C(=O)C(C)Oc2cccc1ccccc12 InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Positive no information RMS: Denmark Napropamide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is identical to the substance Napropamide 239-333-3 15299-99-7 N,N-diethyl-2-(1-naphthyloxy)propanamide Napropamide C17H21NO2 CCN(CC)C(=O)C(C)Oc2cccc1ccccc12 InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Denmark Napropamide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is identical to the substance Napropamide 239-333-3 15299-99-7 N,N-diethyl-2-(1-naphthyloxy)propanamide Napropamide C17H21NO2 CCN(CC)C(=O)C(C)Oc2cccc1ccccc12 InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Denmark Napropamide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is identical to the substance Napropamide 239-333-3 15299-99-7 N,N-diethyl-2-(1-naphthyloxy)propanamide Napropamide C17H21NO2 CCN(CC)C(=O)C(C)Oc2cccc1ccccc12 InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Positive RMS: Denmark Napropamide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is identical to the substance Napropamide 239-333-3 15299-99-7 N,N-diethyl-2-(1-naphthyloxy)propanamide Napropamide C17H21NO2 CCN(CC)C(=O)C(C)Oc2cccc1ccccc12 InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: Denmark Napropamide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is identical to the substance Napropamide 239-333-3 15299-99-7 N,N-diethyl-2-(1-naphthyloxy)propanamide Napropamide C17H21NO2 CCN(CC)C(=O)C(C)Oc2cccc1ccccc12 InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative RMS: Denmark Napropamide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is identical to the substance Napropamide 239-333-3 15299-99-7 N,N-diethyl-2-(1-naphthyloxy)propanamide Napropamide C17H21NO2 CCN(CC)C(=O)C(C)Oc2cccc1ccccc12 InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative RMS: Denmark Napropamide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is identical to the substance Napropamide 239-333-3 15299-99-7 N,N-diethyl-2-(1-naphthyloxy)propanamide Napropamide C17H21NO2 CCN(CC)C(=O)C(C)Oc2cccc1ccccc12 InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3 organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Human (as organism) HeLa cells Not reported yes, concurrent vehicle with Negative RMS: Denmark Napropamide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is identical to the substance Napropamide 239-333-3 15299-99-7 N,N-diethyl-2-(1-naphthyloxy)propanamide Napropamide C17H21NO2 CCN(CC)C(=O)C(C)Oc2cccc1ccccc12 InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3 organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Human (as organism) HeLa cells Not reported yes, concurrent vehicle without Negative RMS: Denmark Napropamide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is identical to the substance Napropamide 239-333-3 15299-99-7 N,N-diethyl-2-(1-naphthyloxy)propanamide Napropamide C17H21NO2 CCN(CC)C(=O)C(C)Oc2cccc1ccccc12 InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3 organic compound Other Other DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Human (as organism) fibroblast Not reported no data without Negative RMS: Denmark Napropamide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is identical to the substance Napropamide 239-333-3 15299-99-7 N,N-diethyl-2-(1-naphthyloxy)propanamide Napropamide C17H21NO2 CCN(CC)C(=O)C(C)Oc2cccc1ccccc12 InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3 organic compound Other Other DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Human (as organism) fibroblast Not reported no data without Negative RMS: Denmark Napropamide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is identical to the substance Napropamide 239-333-3 15299-99-7 N,N-diethyl-2-(1-naphthyloxy)propanamide Napropamide C17H21NO2 CCN(CC)C(=O)C(C)Oc2cccc1ccccc12 InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3 organic compound Other Other DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Human (as organism) fibroblast Not reported yes, concurrent vehicle with Positive RMS: Denmark Napropamide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is identical to the substance Napropamide 239-333-3 15299-99-7 N,N-diethyl-2-(1-naphthyloxy)propanamide Napropamide C17H21NO2 CCN(CC)C(=O)C(C)Oc2cccc1ccccc12 InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3 organic compound Other Other DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Human (as organism) fibroblast Not reported yes, concurrent vehicle without Negative RMS: Denmark Napropamide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is identical to the substance Napropamide 239-333-3 15299-99-7 N,N-diethyl-2-(1-naphthyloxy)propanamide Napropamide C17H21NO2 CCN(CC)C(=O)C(C)Oc2cccc1ccccc12 InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Denmark Napropamide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is identical to the substance Napropamide 239-333-3 15299-99-7 N,N-diethyl-2-(1-naphthyloxy)propanamide Napropamide C17H21NO2 CCN(CC)C(=O)C(C)Oc2cccc1ccccc12 InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 72.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Denmark Napropamide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is identical to the substance Napropamide 239-333-3 15299-99-7 N,N-diethyl-2-(1-naphthyloxy)propanamide Napropamide C17H21NO2 CCN(CC)C(=O)C(C)Oc2cccc1ccccc12 InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Denmark Napropamide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is identical to the substance Napropamide 239-333-3 15299-99-7 N,N-diethyl-2-(1-naphthyloxy)propanamide Napropamide C17H21NO2 CCN(CC)C(=O)C(C)Oc2cccc1ccccc12 InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 5 Female oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Denmark Napropamide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is identical to the substance Napropamide 239-333-3 15299-99-7 N,N-diethyl-2-(1-naphthyloxy)propanamide Napropamide C17H21NO2 CCN(CC)C(=O)C(C)Oc2cccc1ccccc12 InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3 organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Alderly Park Rat 5 Male oral: gavage 12.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Denmark Napropamide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is identical to the substance Napropamide 239-333-3 15299-99-7 N,N-diethyl-2-(1-naphthyloxy)propanamide Napropamide C17H21NO2 CCN(CC)C(=O)C(C)Oc2cccc1ccccc12 InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3 organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Alderly Park Rat 5 Male oral: gavage 4.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Denmark Napropamide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance 2-(naphthalen-1-yloxy)propanoic acid 2-naphthalen-1-yloxypropanoic acid Not in list C13H12O3 CC(C(=O)O)OC1=CC=CC2=CC=CC=C21 InChI=1S/C13H12O3/c1-9(13(14)15)16-12-8-4-6-10-5-2-3-7-11(10)12/h2-9H,1H3,(H,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Denmark Napropamide (Addendum 2) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance 2-(naphthalen-1-yloxy)propanoic acid 2-naphthalen-1-yloxypropanoic acid Not in list C13H12O3 CC(C(=O)O)OC1=CC=CC2=CC=CC=C21 InChI=1S/C13H12O3/c1-9(13(14)15)16-12-8-4-6-10-5-2-3-7-11(10)12/h2-9H,1H3,(H,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Denmark Napropamide (Addendum 2) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance 2-(naphthalen-1-yloxy)propanoic acid 2-naphthalen-1-yloxypropanoic acid Not in list C13H12O3 CC(C(=O)O)OC1=CC=CC2=CC=CC=C21 InChI=1S/C13H12O3/c1-9(13(14)15)16-12-8-4-6-10-5-2-3-7-11(10)12/h2-9H,1H3,(H,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Denmark Napropamide (Addendum 2) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance 2-(naphthalen-1-yloxy)propanoic acid 2-naphthalen-1-yloxypropanoic acid Not in list C13H12O3 CC(C(=O)O)OC1=CC=CC2=CC=CC=C21 InChI=1S/C13H12O3/c1-9(13(14)15)16-12-8-4-6-10-5-2-3-7-11(10)12/h2-9H,1H3,(H,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Denmark Napropamide (Addendum 2) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance 2-(naphthalen-1-yloxy)propanoic acid 2-naphthalen-1-yloxypropanoic acid Not in list C13H12O3 CC(C(=O)O)OC1=CC=CC2=CC=CC=C21 InChI=1S/C13H12O3/c1-9(13(14)15)16-12-8-4-6-10-5-2-3-7-11(10)12/h2-9H,1H3,(H,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Denmark Napropamide (Addendum 2) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance 2-(naphthalen-1-yloxy)propanoic acid 2-naphthalen-1-yloxypropanoic acid Not in list C13H12O3 CC(C(=O)O)OC1=CC=CC2=CC=CC=C21 InChI=1S/C13H12O3/c1-9(13(14)15)16-12-8-4-6-10-5-2-3-7-11(10)12/h2-9H,1H3,(H,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Denmark Napropamide (Addendum 2) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance 2-(naphthalen-1-yloxy)propanoic acid 2-naphthalen-1-yloxypropanoic acid Not in list C13H12O3 CC(C(=O)O)OC1=CC=CC2=CC=CC=C21 InChI=1S/C13H12O3/c1-9(13(14)15)16-12-8-4-6-10-5-2-3-7-11(10)12/h2-9H,1H3,(H,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Denmark Napropamide (Addendum 2) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance 2-(naphthalen-1-yloxy)propanoic acid 2-naphthalen-1-yloxypropanoic acid Not in list C13H12O3 CC(C(=O)O)OC1=CC=CC2=CC=CC=C21 InChI=1S/C13H12O3/c1-9(13(14)15)16-12-8-4-6-10-5-2-3-7-11(10)12/h2-9H,1H3,(H,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Denmark Napropamide (Addendum 2) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance 2-(naphthalen-1-yloxy)propanoic acid 2-naphthalen-1-yloxypropanoic acid Not in list C13H12O3 CC(C(=O)O)OC1=CC=CC2=CC=CC=C21 InChI=1S/C13H12O3/c1-9(13(14)15)16-12-8-4-6-10-5-2-3-7-11(10)12/h2-9H,1H3,(H,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Denmark Napropamide (Addendum 2) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance 2-(naphthalen-1-yloxy)propanoic acid 2-naphthalen-1-yloxypropanoic acid Not in list C13H12O3 CC(C(=O)O)OC1=CC=CC2=CC=CC=C21 InChI=1S/C13H12O3/c1-9(13(14)15)16-12-8-4-6-10-5-2-3-7-11(10)12/h2-9H,1H3,(H,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Denmark Napropamide (Addendum 2) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance 2-(naphthalen-1-yloxy)propanoic acid 2-naphthalen-1-yloxypropanoic acid Not in list C13H12O3 CC(C(=O)O)OC1=CC=CC2=CC=CC=C21 InChI=1S/C13H12O3/c1-9(13(14)15)16-12-8-4-6-10-5-2-3-7-11(10)12/h2-9H,1H3,(H,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Denmark Napropamide (Addendum 2) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance 2-(naphthalen-1-yloxy)propanoic acid 2-naphthalen-1-yloxypropanoic acid Not in list C13H12O3 CC(C(=O)O)OC1=CC=CC2=CC=CC=C21 InChI=1S/C13H12O3/c1-9(13(14)15)16-12-8-4-6-10-5-2-3-7-11(10)12/h2-9H,1H3,(H,14,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Denmark Napropamide (Addendum 2) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance 2-(naphthalen-1-yloxy)propanoic acid 2-naphthalen-1-yloxypropanoic acid Not in list C13H12O3 CC(C(=O)O)OC1=CC=CC2=CC=CC=C21 InChI=1S/C13H12O3/c1-9(13(14)15)16-12-8-4-6-10-5-2-3-7-11(10)12/h2-9H,1H3,(H,14,15) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Positive RMS: Denmark Napropamide (Addendum 2) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance 2-(naphthalen-1-yloxy)propanoic acid 2-naphthalen-1-yloxypropanoic acid Not in list C13H12O3 CC(C(=O)O)OC1=CC=CC2=CC=CC=C21 InChI=1S/C13H12O3/c1-9(13(14)15)16-12-8-4-6-10-5-2-3-7-11(10)12/h2-9H,1H3,(H,14,15) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Denmark Napropamide (Addendum 2) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance 2-(naphthalen-1-yloxy)propanoic acid 2-naphthalen-1-yloxypropanoic acid Not in list C13H12O3 CC(C(=O)O)OC1=CC=CC2=CC=CC=C21 InChI=1S/C13H12O3/c1-9(13(14)15)16-12-8-4-6-10-5-2-3-7-11(10)12/h2-9H,1H3,(H,14,15) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 7 Male oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Denmark Napropamide (Addendum 2) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance 2-(naphthalen-1-yloxy)propanoic acid 2-naphthalen-1-yloxypropanoic acid Not in list C13H12O3 CC(C(=O)O)OC1=CC=CC2=CC=CC=C21 InChI=1S/C13H12O3/c1-9(13(14)15)16-12-8-4-6-10-5-2-3-7-11(10)12/h2-9H,1H3,(H,14,15) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 7 Male oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Denmark Napropamide (Addendum 2) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance Phthalic acid 201-873-2 88-99-3 phthalic acid Not in list C8H6O4 C1=CC=C(C(=C1)C(=O)O)C(=O)O InChI=1S/C8H6O4/c9-7(10)5-3-1-2-4-6(5)8(11)12/h1-4H,(H,9,10)(H,11,12) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) No data Acceptable House mouse (as animal) Swiss 20 Male intraperitoneal 5.0000000000 D yes, concurrent vehicle not applicable Positive RMS: Denmark Napropamide (Addendum 1) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance 2-hydroxynaphthalene-1,4-dione 201-496-3 83-72-7 4-hydroxynaphthalene-1,2-dione Not in list C10H6O3 C1=CC=C2C(=C1)C(=CC(=O)C2=O)O InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Denmark Napropamide (Addendum 1) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance 2-hydroxynaphthalene-1,4-dione 201-496-3 83-72-7 4-hydroxynaphthalene-1,2-dione Not in list C10H6O3 C1=CC=C2C(=C1)C(=CC(=O)C2=O)O InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Denmark Napropamide (Addendum 1) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance 2-hydroxynaphthalene-1,4-dione 201-496-3 83-72-7 4-hydroxynaphthalene-1,2-dione Not in list C10H6O3 C1=CC=C2C(=C1)C(=CC(=O)C2=O)O InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 72.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Denmark Napropamide (Addendum 1) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Orange oil single chemical entity Component is part of a group assessment d-limonene 227-813-5 5989-27-5 (4R)-1-methyl-4-(1-methylethenyl)cyclohexene Not in list C10H16 CC(=C)[C@@H]1CCC(=CC1)C InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1 organic compound DSSTox DSSTox gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil single chemical entity Component is part of a group assessment d-limonene 227-813-5 5989-27-5 (4R)-1-methyl-4-(1-methylethenyl)cyclohexene Not in list C10H16 CC(=C)[C@@H]1CCC(=CC1)C InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1 organic compound DSSTox DSSTox gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil single chemical entity Component is part of a group assessment d-limonene 227-813-5 5989-27-5 (4R)-1-methyl-4-(1-methylethenyl)cyclohexene Not in list C10H16 CC(=C)[C@@H]1CCC(=CC1)C InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1 organic compound DSSTox DSSTox gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil single chemical entity Component is part of a group assessment d-limonene 227-813-5 5989-27-5 (4R)-1-methyl-4-(1-methylethenyl)cyclohexene Not in list C10H16 CC(=C)[C@@H]1CCC(=CC1)C InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1 organic compound DSSTox DSSTox gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil single chemical entity Component is part of a group assessment d-limonene 227-813-5 5989-27-5 (4R)-1-methyl-4-(1-methylethenyl)cyclohexene Not in list C10H16 CC(=C)[C@@H]1CCC(=CC1)C InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1 organic compound DSSTox DSSTox gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil single chemical entity Component is part of a group assessment d-limonene 227-813-5 5989-27-5 (4R)-1-methyl-4-(1-methylethenyl)cyclohexene Not in list C10H16 CC(=C)[C@@H]1CCC(=CC1)C InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1 organic compound DSSTox DSSTox gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil single chemical entity Component is part of a group assessment d-limonene 227-813-5 5989-27-5 (4R)-1-methyl-4-(1-methylethenyl)cyclohexene Not in list C10H16 CC(=C)[C@@H]1CCC(=CC1)C InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1 organic compound DSSTox DSSTox gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil single chemical entity Component is part of a group assessment d-limonene 227-813-5 5989-27-5 (4R)-1-methyl-4-(1-methylethenyl)cyclohexene Not in list C10H16 CC(=C)[C@@H]1CCC(=CC1)C InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1 organic compound DSSTox DSSTox gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil single chemical entity Component is part of a group assessment d-limonene 227-813-5 5989-27-5 (4R)-1-methyl-4-(1-methylethenyl)cyclohexene Not in list C10H16 CC(=C)[C@@H]1CCC(=CC1)C InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1 organic compound DSSTox DSSTox gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil single chemical entity Component is part of a group assessment d-limonene 227-813-5 5989-27-5 (4R)-1-methyl-4-(1-methylethenyl)cyclohexene Not in list C10H16 CC(=C)[C@@H]1CCC(=CC1)C InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1 organic compound DSSTox DSSTox gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil single chemical entity Component is part of a group assessment d-limonene 227-813-5 5989-27-5 (4R)-1-methyl-4-(1-methylethenyl)cyclohexene Not in list C10H16 CC(=C)[C@@H]1CCC(=CC1)C InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1 organic compound DSSTox DSSTox gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil single chemical entity Component is part of a group assessment d-limonene 227-813-5 5989-27-5 (4R)-1-methyl-4-(1-methylethenyl)cyclohexene Not in list C10H16 CC(=C)[C@@H]1CCC(=CC1)C InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1 organic compound DSSTox DSSTox gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil single chemical entity Component is part of a group assessment d-limonene 227-813-5 5989-27-5 (4R)-1-methyl-4-(1-methylethenyl)cyclohexene Not in list C10H16 CC(=C)[C@@H]1CCC(=CC1)C InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1 organic compound DSSTox DSSTox gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil single chemical entity Component is part of a group assessment d-limonene 227-813-5 5989-27-5 (4R)-1-methyl-4-(1-methylethenyl)cyclohexene Not in list C10H16 CC(=C)[C@@H]1CCC(=CC1)C InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1 organic compound DSSTox DSSTox gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil single chemical entity Component is part of a group assessment d-limonene 227-813-5 5989-27-5 (4R)-1-methyl-4-(1-methylethenyl)cyclohexene Not in list C10H16 CC(=C)[C@@H]1CCC(=CC1)C InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1 organic compound DSSTox DSSTox gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil single chemical entity Component is part of a group assessment d-limonene 227-813-5 5989-27-5 (4R)-1-methyl-4-(1-methylethenyl)cyclohexene Not in list C10H16 CC(=C)[C@@H]1CCC(=CC1)C InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1 organic compound DSSTox DSSTox gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil single chemical entity Component is part of a group assessment d-limonene 227-813-5 5989-27-5 (4R)-1-methyl-4-(1-methylethenyl)cyclohexene Not in list C10H16 CC(=C)[C@@H]1CCC(=CC1)C InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1 organic compound DSSTox DSSTox gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil single chemical entity Component is part of a group assessment d-limonene 227-813-5 5989-27-5 (4R)-1-methyl-4-(1-methylethenyl)cyclohexene Not in list C10H16 CC(=C)[C@@H]1CCC(=CC1)C InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1 organic compound DSSTox DSSTox gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil single chemical entity Component is part of a group assessment d-limonene 227-813-5 5989-27-5 (4R)-1-methyl-4-(1-methylethenyl)cyclohexene Not in list C10H16 CC(=C)[C@@H]1CCC(=CC1)C InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1 organic compound DSSTox DSSTox gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil single chemical entity Component is part of a group assessment d-limonene 227-813-5 5989-27-5 (4R)-1-methyl-4-(1-methylethenyl)cyclohexene Not in list C10H16 CC(=C)[C@@H]1CCC(=CC1)C InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1 organic compound DSSTox DSSTox gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil single chemical entity Component is part of a group assessment d-limonene 227-813-5 5989-27-5 (4R)-1-methyl-4-(1-methylethenyl)cyclohexene Not in list C10H16 CC(=C)[C@@H]1CCC(=CC1)C InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1 organic compound DSSTox DSSTox gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil single chemical entity Component is part of a group assessment d-limonene 227-813-5 5989-27-5 (4R)-1-methyl-4-(1-methylethenyl)cyclohexene Not in list C10H16 CC(=C)[C@@H]1CCC(=CC1)C InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1 organic compound DSSTox DSSTox gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil single chemical entity Component is part of a group assessment d-limonene 227-813-5 5989-27-5 (4R)-1-methyl-4-(1-methylethenyl)cyclohexene Not in list C10H16 CC(=C)[C@@H]1CCC(=CC1)C InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1 organic compound DSSTox DSSTox gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil single chemical entity Component is part of a group assessment d-limonene 227-813-5 5989-27-5 (4R)-1-methyl-4-(1-methylethenyl)cyclohexene Not in list C10H16 CC(=C)[C@@H]1CCC(=CC1)C InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1 organic compound DSSTox DSSTox gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil single chemical entity Component is part of a group assessment d-limonene 227-813-5 5989-27-5 (4R)-1-methyl-4-(1-methylethenyl)cyclohexene Not in list C10H16 CC(=C)[C@@H]1CCC(=CC1)C InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1 organic compound DSSTox DSSTox gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil single chemical entity Component is part of a group assessment d-limonene 227-813-5 5989-27-5 (4R)-1-methyl-4-(1-methylethenyl)cyclohexene Not in list C10H16 CC(=C)[C@@H]1CCC(=CC1)C InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1 organic compound DSSTox DSSTox gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil single chemical entity Component is part of a group assessment d-limonene 227-813-5 5989-27-5 (4R)-1-methyl-4-(1-methylethenyl)cyclohexene Not in list C10H16 CC(=C)[C@@H]1CCC(=CC1)C InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1 organic compound DSSTox DSSTox gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil single chemical entity Component is part of a group assessment d-limonene 227-813-5 5989-27-5 (4R)-1-methyl-4-(1-methylethenyl)cyclohexene Not in list C10H16 CC(=C)[C@@H]1CCC(=CC1)C InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1 organic compound DSSTox DSSTox gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil single chemical entity Component is part of a group assessment d-limonene 227-813-5 5989-27-5 (4R)-1-methyl-4-(1-methylethenyl)cyclohexene Not in list C10H16 CC(=C)[C@@H]1CCC(=CC1)C InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1 organic compound DSSTox DSSTox gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil single chemical entity Component is part of a group assessment d-limonene 227-813-5 5989-27-5 (4R)-1-methyl-4-(1-methylethenyl)cyclohexene Not in list C10H16 CC(=C)[C@@H]1CCC(=CC1)C InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1 organic compound DSSTox DSSTox gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil single chemical entity Component is part of a group assessment d-limonene 227-813-5 5989-27-5 (4R)-1-methyl-4-(1-methylethenyl)cyclohexene Not in list C10H16 CC(=C)[C@@H]1CCC(=CC1)C InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1 organic compound DSSTox DSSTox gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil single chemical entity Component is part of a group assessment d-limonene 227-813-5 5989-27-5 (4R)-1-methyl-4-(1-methylethenyl)cyclohexene Not in list C10H16 CC(=C)[C@@H]1CCC(=CC1)C InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1 organic compound DSSTox DSSTox gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil single chemical entity Component is part of a group assessment d-limonene 227-813-5 5989-27-5 (4R)-1-methyl-4-(1-methylethenyl)cyclohexene Not in list C10H16 CC(=C)[C@@H]1CCC(=CC1)C InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1 organic compound DSSTox DSSTox gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil single chemical entity Component is part of a group assessment d-limonene 227-813-5 5989-27-5 (4R)-1-methyl-4-(1-methylethenyl)cyclohexene Not in list C10H16 CC(=C)[C@@H]1CCC(=CC1)C InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1 organic compound DSSTox DSSTox gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil single chemical entity Component is part of a group assessment d-limonene 227-813-5 5989-27-5 (4R)-1-methyl-4-(1-methylethenyl)cyclohexene Not in list C10H16 CC(=C)[C@@H]1CCC(=CC1)C InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1 organic compound DSSTox DSSTox gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil single chemical entity Component is part of a group assessment d-limonene 227-813-5 5989-27-5 (4R)-1-methyl-4-(1-methylethenyl)cyclohexene Not in list C10H16 CC(=C)[C@@H]1CCC(=CC1)C InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1 organic compound DSSTox DSSTox gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil single chemical entity Component is part of a group assessment d-limonene 227-813-5 5989-27-5 (4R)-1-methyl-4-(1-methylethenyl)cyclohexene Not in list C10H16 CC(=C)[C@@H]1CCC(=CC1)C InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1 organic compound DSSTox DSSTox gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil single chemical entity Component is part of a group assessment d-limonene 227-813-5 5989-27-5 (4R)-1-methyl-4-(1-methylethenyl)cyclohexene Not in list C10H16 CC(=C)[C@@H]1CCC(=CC1)C InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1 organic compound DSSTox DSSTox gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil complex product: derived from botanical sources Component is identical to the substance Orange oil Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil complex product: derived from botanical sources Component is identical to the substance Orange oil Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil complex product: derived from botanical sources Component is identical to the substance Orange oil Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil complex product: derived from botanical sources Component is identical to the substance Orange oil Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil complex product: derived from botanical sources Component is identical to the substance Orange oil Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported no data without Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil complex product: derived from botanical sources Component is identical to the substance Orange oil Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported no data with Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil complex product: derived from botanical sources Component is identical to the substance Orange oil Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil complex product: derived from botanical sources Component is identical to the substance Orange oil Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil complex product: derived from botanical sources Component is identical to the substance Orange oil Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil complex product: derived from botanical sources Component is identical to the substance Orange oil Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil single chemical entity Component is part of a group assessment d-limonene 227-813-5 5989-27-5 (4R)-1-methyl-4-(1-methylethenyl)cyclohexene Not in list C10H16 CC(=C)[C@@H]1CCC(=CC1)C InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1 organic compound DSSTox DSSTox gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil single chemical entity Component is part of a group assessment d-limonene 227-813-5 5989-27-5 (4R)-1-methyl-4-(1-methylethenyl)cyclohexene Not in list C10H16 CC(=C)[C@@H]1CCC(=CC1)C InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1 organic compound DSSTox DSSTox gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil single chemical entity Component is part of a group assessment d-limonene 227-813-5 5989-27-5 (4R)-1-methyl-4-(1-methylethenyl)cyclohexene Not in list C10H16 CC(=C)[C@@H]1CCC(=CC1)C InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1 organic compound DSSTox DSSTox DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil single chemical entity Component is part of a group assessment d-limonene 227-813-5 5989-27-5 (4R)-1-methyl-4-(1-methylethenyl)cyclohexene Not in list C10H16 CC(=C)[C@@H]1CCC(=CC1)C InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1 organic compound DSSTox DSSTox DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil single chemical entity Component is part of a group assessment d-limonene 227-813-5 5989-27-5 (4R)-1-methyl-4-(1-methylethenyl)cyclohexene Not in list C10H16 CC(=C)[C@@H]1CCC(=CC1)C InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1 organic compound DSSTox DSSTox chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil single chemical entity Component is part of a group assessment d-limonene 227-813-5 5989-27-5 (4R)-1-methyl-4-(1-methylethenyl)cyclohexene Not in list C10H16 CC(=C)[C@@H]1CCC(=CC1)C InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1 organic compound DSSTox DSSTox chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil single chemical entity Component is part of a group assessment d-limonene 227-813-5 5989-27-5 (4R)-1-methyl-4-(1-methylethenyl)cyclohexene Not in list C10H16 CC(=C)[C@@H]1CCC(=CC1)C InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1 organic compound DSSTox DSSTox gene mutation mouse spot test in vivo According to OECD Guideline 484 (Genetic Toxicology: Mouse Spot Test) No Acceptable House mouse (as animal) C57BL Male/Female intraperitoneal yes not applicable Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil single chemical entity Component is part of a group assessment d-limonene 227-813-5 5989-27-5 (4R)-1-methyl-4-(1-methylethenyl)cyclohexene Not in list C10H16 CC(=C)[C@@H]1CCC(=CC1)C InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1 organic compound DSSTox DSSTox DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo Equivalent or similar to OECD Guideline 489 No data Acceptable Rat (as animal) Sprague-Dawley 4 Male oral: gavage 6.0000000000 h yes not applicable Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil single chemical entity Component is part of a group assessment d-limonene 227-813-5 5989-27-5 (4R)-1-methyl-4-(1-methylethenyl)cyclohexene Not in list C10H16 CC(=C)[C@@H]1CCC(=CC1)C InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1 organic compound DSSTox DSSTox DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo Equivalent or similar to OECD Guideline 489 No data Acceptable Rat (as animal) Sprague-Dawley 4 Male oral: gavage 26.0000000000 h yes not applicable Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil single chemical entity Component is part of a group assessment d-limonene 227-813-5 5989-27-5 (4R)-1-methyl-4-(1-methylethenyl)cyclohexene Not in list C10H16 CC(=C)[C@@H]1CCC(=CC1)C InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1 organic compound DSSTox DSSTox gene mutation other in vivo No guideline available Not reported Not applicable Acceptable Rat (as animal) 10 Male oral: feed 10.0000000000 D yes not applicable Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil single chemical entity Component is part of a group assessment d-limonene 227-813-5 5989-27-5 (4R)-1-methyl-4-(1-methylethenyl)cyclohexene Not in list C10H16 CC(=C)[C@@H]1CCC(=CC1)C InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1 organic compound DSSTox DSSTox gene mutation other in vivo No guideline available Not reported Not applicable Acceptable Rat (as animal) 10 Male oral: feed 10.0000000000 D yes not applicable Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil complex product: derived from botanical sources Component is identical to the substance Orange oil Not in list organic no structure DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported no data no data Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil complex product: derived from botanical sources Component is identical to the substance Orange oil Not in list organic no structure DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported no data no data Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil single chemical entity Component is part of a group assessment d-limonene 227-813-5 5989-27-5 (4R)-1-methyl-4-(1-methylethenyl)cyclohexene Not in list C10H16 CC(=C)[C@@H]1CCC(=CC1)C InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1 organic compound DSSTox DSSTox DNA damage and/or repair in vitro mammalian cell transformation assay in vitro No guideline available Not reported Not applicable Acceptable Hamster (as animal) embryo cells Not reported no data no data Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil single chemical entity Component is part of a group assessment Linalool 201-134-4 78-70-6 3,7-dimethylocta-1,6-dien-3-ol linalool C10H18O CC(=CCCC(C)(C=C)O)C InChI=1S/C10H18O/c1-5-10(4,11)8-6-7-9(2)3/h5,7,11H,1,6,8H2,2-4H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No data Acceptable Hamster (as animal) CHO Not reported no data no data Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil single chemical entity Component is part of a group assessment β-myrcene 204-622-5 123-35-3 7-methyl-3-methylideneocta-1,6-diene myrcene C10H16 CC(=CCCC(=C)C=C)C InChI=1S/C10H16/c1-5-10(4)8-6-7-9(2)3/h5,7H,1,4,6,8H2,2-3H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No data Acceptable Hamster (as animal) CHO Not reported no data no data Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil single chemical entity Component is part of a group assessment β-myrcene 204-622-5 123-35-3 7-methyl-3-methylideneocta-1,6-diene myrcene C10H16 CC(=CCCC(=C)C=C)C InChI=1S/C10H16/c1-5-10(4)8-6-7-9(2)3/h5,7H,1,4,6,8H2,2-3H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No data Acceptable Human (as organism) lymphocytes Not reported no data without Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil single chemical entity Component is part of a group assessment β-myrcene 204-622-5 123-35-3 7-methyl-3-methylideneocta-1,6-diene myrcene C10H16 CC(=CCCC(=C)C=C)C InChI=1S/C10H16/c1-5-10(4)8-6-7-9(2)3/h5,7H,1,4,6,8H2,2-3H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No data Acceptable Human (as organism) lymphocytes Not reported no data with Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil single chemical entity Component is part of a group assessment β-myrcene 204-622-5 123-35-3 7-methyl-3-methylideneocta-1,6-diene myrcene C10H16 CC(=CCCC(=C)C=C)C InChI=1S/C10H16/c1-5-10(4)8-6-7-9(2)3/h5,7H,1,4,6,8H2,2-3H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Wistar 8 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Orange oil single chemical entity Component is part of a group assessment β-myrcene 204-622-5 123-35-3 7-methyl-3-methylideneocta-1,6-diene myrcene C10H16 CC(=CCCC(=C)C=C)C InChI=1S/C10H16/c1-5-10(4)8-6-7-9(2)3/h5,7H,1,4,6,8H2,2-3H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Wistar 8 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: France Orange oil 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil 11Feb2013 2013 doi:10.2903/j.efsa.2013.3090
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance 2-hydroxynaphthalene-1,4-dione 201-496-3 83-72-7 4-hydroxynaphthalene-1,2-dione Not in list C10H6O3 C1=CC=C2C(=C1)C(=CC(=O)C2=O)O InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Negative no information RMS: Denmark Napropamide (Addendum 1) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance 2-hydroxynaphthalene-1,4-dione 201-496-3 83-72-7 4-hydroxynaphthalene-1,2-dione Not in list C10H6O3 C1=CC=C2C(=C1)C(=CC(=O)C2=O)O InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: Denmark Napropamide (Addendum 1) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance 2-hydroxynaphthalene-1,4-dione 201-496-3 83-72-7 4-hydroxynaphthalene-1,2-dione Not in list C10H6O3 C1=CC=C2C(=C1)C(=CC(=O)C2=O)O InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable House mouse (as animal) CD-1 No data intraperitoneal 72.0000000000 h yes not applicable Negative direct evidence-cytotoxicity RMS: Denmark Napropamide (Addendum 1) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance 2-hydroxynaphthalene-1,4-dione 201-496-3 83-72-7 4-hydroxynaphthalene-1,2-dione Not in list C10H6O3 C1=CC=C2C(=C1)C(=CC(=O)C2=O)O InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Swiss 10 Male/Female oral: gavage 24.0000000000 h yes not applicable Negative no evidence RMS: Denmark Napropamide (Addendum 1) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance 2-hydroxynaphthalene-1,4-dione 201-496-3 83-72-7 4-hydroxynaphthalene-1,2-dione Not in list C10H6O3 C1=CC=C2C(=C1)C(=CC(=O)C2=O)O InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No data Acceptable Rat (as animal) Sprague-Dawley 6 Male/Female oral: unspecified 28.0000000000 D yes, concurrent vehicle not applicable Negative RMS: Denmark Napropamide (Addendum 1) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance 2-hydroxynaphthalene-1,4-dione 201-496-3 83-72-7 4-hydroxynaphthalene-1,2-dione Not in list C10H6O3 C1=CC=C2C(=C1)C(=CC(=O)C2=O)O InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Denmark Napropamide (Addendum 1) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance 2-hydroxynaphthalene-1,4-dione 201-496-3 83-72-7 4-hydroxynaphthalene-1,2-dione Not in list C10H6O3 C1=CC=C2C(=C1)C(=CC(=O)C2=O)O InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Negative RMS: Denmark Napropamide (Addendum 1) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance 2-hydroxynaphthalene-1,4-dione 201-496-3 83-72-7 4-hydroxynaphthalene-1,2-dione Not in list C10H6O3 C1=CC=C2C(=C1)C(=CC(=O)C2=O)O InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No data Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: Denmark Napropamide (Addendum 1) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance 2-hydroxynaphthalene-1,4-dione 201-496-3 83-72-7 4-hydroxynaphthalene-1,2-dione Not in list C10H6O3 C1=CC=C2C(=C1)C(=CC(=O)C2=O)O InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Denmark Napropamide (Addendum 1) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance 2-hydroxynaphthalene-1,4-dione 201-496-3 83-72-7 4-hydroxynaphthalene-1,2-dione Not in list C10H6O3 C1=CC=C2C(=C1)C(=CC(=O)C2=O)O InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Denmark Napropamide (Addendum 1) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance 2-hydroxynaphthalene-1,4-dione 201-496-3 83-72-7 4-hydroxynaphthalene-1,2-dione Not in list C10H6O3 C1=CC=C2C(=C1)C(=CC(=O)C2=O)O InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Swiss 10 Male oral: gavage 72.0000000000 h yes not applicable Negative no evidence RMS: Denmark Napropamide (Addendum 1) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance 2-hydroxynaphthalene-1,4-dione 201-496-3 83-72-7 4-hydroxynaphthalene-1,2-dione Not in list C10H6O3 C1=CC=C2C(=C1)C(=CC(=O)C2=O)O InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Denmark Napropamide (Addendum 1) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance 2-hydroxynaphthalene-1,4-dione 201-496-3 83-72-7 4-hydroxynaphthalene-1,2-dione Not in list C10H6O3 C1=CC=C2C(=C1)C(=CC(=O)C2=O)O InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: Denmark Napropamide (Addendum 1) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance 2-hydroxynaphthalene-1,4-dione 201-496-3 83-72-7 4-hydroxynaphthalene-1,2-dione Not in list C10H6O3 C1=CC=C2C(=C1)C(=CC(=O)C2=O)O InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Swiss 10 Male/Female oral: gavage 48.0000000000 h yes not applicable Negative no evidence RMS: Denmark Napropamide (Addendum 1) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance 2-hydroxynaphthalene-1,4-dione 201-496-3 83-72-7 4-hydroxynaphthalene-1,2-dione Not in list C10H6O3 C1=CC=C2C(=C1)C(=CC(=O)C2=O)O InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Hamster (as animal) Chinese 10 Male/Female oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Denmark Napropamide (Addendum 1) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance 2-hydroxynaphthalene-1,4-dione 201-496-3 83-72-7 4-hydroxynaphthalene-1,2-dione Not in list C10H6O3 C1=CC=C2C(=C1)C(=CC(=O)C2=O)O InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Hamster (as animal) Chinese 10 Male/Female oral: unspecified 48.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Denmark Napropamide (Addendum 1) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance 2-hydroxynaphthalene-1,4-dione 201-496-3 83-72-7 4-hydroxynaphthalene-1,2-dione Not in list C10H6O3 C1=CC=C2C(=C1)C(=CC(=O)C2=O)O InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Denmark Napropamide (Addendum 1) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance 2-hydroxynaphthalene-1,4-dione 201-496-3 83-72-7 4-hydroxynaphthalene-1,2-dione Not in list C10H6O3 C1=CC=C2C(=C1)C(=CC(=O)C2=O)O InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Not reported 5 Male oral: unspecified 2.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Denmark Napropamide (Addendum 1) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance 2-hydroxynaphthalene-1,4-dione 201-496-3 83-72-7 4-hydroxynaphthalene-1,2-dione Not in list C10H6O3 C1=CC=C2C(=C1)C(=CC(=O)C2=O)O InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable House mouse (as animal) CD-1 No data intraperitoneal 24.0000000000 h yes not applicable Negative direct evidence-cytotoxicity RMS: Denmark Napropamide (Addendum 1) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance 2-hydroxynaphthalene-1,4-dione 201-496-3 83-72-7 4-hydroxynaphthalene-1,2-dione Not in list C10H6O3 C1=CC=C2C(=C1)C(=CC(=O)C2=O)O InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 72.0000000000 h yes not applicable Positive direct evidence-cytotoxicity RMS: Denmark Napropamide (Addendum 1) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance 2-hydroxynaphthalene-1,4-dione 201-496-3 83-72-7 4-hydroxynaphthalene-1,2-dione Not in list C10H6O3 C1=CC=C2C(=C1)C(=CC(=O)C2=O)O InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) Swiss Male/Female oral: unspecified 48.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Denmark Napropamide (Addendum 1) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance 2-hydroxynaphthalene-1,4-dione 201-496-3 83-72-7 4-hydroxynaphthalene-1,2-dione Not in list C10H6O3 C1=CC=C2C(=C1)C(=CC(=O)C2=O)O InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 72.0000000000 h yes not applicable Positive no evidence RMS: Denmark Napropamide (Addendum 1) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance 2-hydroxynaphthalene-1,4-dione 201-496-3 83-72-7 4-hydroxynaphthalene-1,2-dione Not in list C10H6O3 C1=CC=C2C(=C1)C(=CC(=O)C2=O)O InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Hamster (as animal) Chinese 10 Male/Female oral: unspecified 6.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Denmark Napropamide (Addendum 1) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance 2-hydroxynaphthalene-1,4-dione 201-496-3 83-72-7 4-hydroxynaphthalene-1,2-dione Not in list C10H6O3 C1=CC=C2C(=C1)C(=CC(=O)C2=O)O InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Positive no information RMS: Denmark Napropamide (Addendum 1) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance 2-hydroxynaphthalene-1,4-dione 201-496-3 83-72-7 4-hydroxynaphthalene-1,2-dione Not in list C10H6O3 C1=CC=C2C(=C1)C(=CC(=O)C2=O)O InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair in vitro mammalian cell transformation assay in vitro No guideline available Not reported Not applicable Acceptable Hamster (as animal) embryo cells Not reported yes with Negative RMS: Denmark Napropamide (Addendum 1) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance 2-hydroxynaphthalene-1,4-dione 201-496-3 83-72-7 4-hydroxynaphthalene-1,2-dione Not in list C10H6O3 C1=CC=C2C(=C1)C(=CC(=O)C2=O)O InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: Denmark Napropamide (Addendum 1) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance 2-hydroxynaphthalene-1,4-dione 201-496-3 83-72-7 4-hydroxynaphthalene-1,2-dione Not in list C10H6O3 C1=CC=C2C(=C1)C(=CC(=O)C2=O)O InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 24.0000000000 h yes not applicable Negative direct evidence-cytotoxicity RMS: Denmark Napropamide (Addendum 1) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance 2-hydroxynaphthalene-1,4-dione 201-496-3 83-72-7 4-hydroxynaphthalene-1,2-dione Not in list C10H6O3 C1=CC=C2C(=C1)C(=CC(=O)C2=O)O InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 48.0000000000 h yes not applicable Negative direct evidence-cytotoxicity RMS: Denmark Napropamide (Addendum 1) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance 2-hydroxynaphthalene-1,4-dione 201-496-3 83-72-7 4-hydroxynaphthalene-1,2-dione Not in list C10H6O3 C1=CC=C2C(=C1)C(=CC(=O)C2=O)O InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No data Acceptable Hamster (as animal) CHO Not reported yes with Positive RMS: Denmark Napropamide (Addendum 1) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance 2-hydroxynaphthalene-1,4-dione 201-496-3 83-72-7 4-hydroxynaphthalene-1,2-dione Not in list C10H6O3 C1=CC=C2C(=C1)C(=CC(=O)C2=O)O InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Denmark Napropamide (Addendum 1) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance 2-hydroxynaphthalene-1,4-dione 201-496-3 83-72-7 4-hydroxynaphthalene-1,2-dione Not in list C10H6O3 C1=CC=C2C(=C1)C(=CC(=O)C2=O)O InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) Swiss Male/Female oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Denmark Napropamide (Addendum 1) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance 2-hydroxynaphthalene-1,4-dione 201-496-3 83-72-7 4-hydroxynaphthalene-1,2-dione Not in list C10H6O3 C1=CC=C2C(=C1)C(=CC(=O)C2=O)O InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable House mouse (as animal) CD-1 No data intraperitoneal 48.0000000000 h yes not applicable Negative direct evidence-cytotoxicity RMS: Denmark Napropamide (Addendum 1) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance 2-hydroxynaphthalene-1,4-dione 201-496-3 83-72-7 4-hydroxynaphthalene-1,2-dione Not in list C10H6O3 C1=CC=C2C(=C1)C(=CC(=O)C2=O)O InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Denmark Napropamide (Addendum 1) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance 2-hydroxynaphthalene-1,4-dione 201-496-3 83-72-7 4-hydroxynaphthalene-1,2-dione Not in list C10H6O3 C1=CC=C2C(=C1)C(=CC(=O)C2=O)O InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Not reported 5 Male oral: unspecified 16.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Denmark Napropamide (Addendum 1) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance 2-hydroxynaphthalene-1,4-dione 201-496-3 83-72-7 4-hydroxynaphthalene-1,2-dione Not in list C10H6O3 C1=CC=C2C(=C1)C(=CC(=O)C2=O)O InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair in vitro mammalian cell transformation assay in vitro No guideline available Not reported Not applicable Acceptable Hamster (as animal) embryo cells Not reported yes with Negative RMS: Denmark Napropamide (Addendum 1) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance 2-hydroxynaphthalene-1,4-dione 201-496-3 83-72-7 4-hydroxynaphthalene-1,2-dione Not in list C10H6O3 C1=CC=C2C(=C1)C(=CC(=O)C2=O)O InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Denmark Napropamide (Addendum 1) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) Not reported Not reported no data no data Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) Not reported Not reported no data no data Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Escherichia coli (as organism) Not reported Not reported no data without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Escherichia coli (as organism) Not reported Not reported no data with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro No guideline followed Not reported Not applicable Acceptable Saccharomyces cerevisiae (as organism) Not reported no data no data Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro No guideline followed Not reported Not applicable Acceptable Saccharomyces cerevisiae (as organism) D7 Not reported no data no data Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro No guideline followed Not reported Not applicable Acceptable Saccharomyces cerevisiae (as organism) D7 Not reported no data without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro No guideline followed Not reported Not applicable Acceptable Saccharomyces cerevisiae (as organism) D7 Not reported no data with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro Equivalent or similar to OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay) No data Acceptable Saccharomyces cerevisiae (as organism) D4 Not reported yes, concurrent vehicle without Positive RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro Equivalent or similar to OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay) No data Acceptable Saccharomyces cerevisiae (as organism) D4 Not reported yes, concurrent vehicle with Positive RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Schizosaccharomyces pombe (as organism) Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Schizosaccharomyces pombe (as organism) Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro No guideline followed Not reported Not applicable Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative no information RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No data Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No data Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro No guideline followed Not reported Not applicable Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro No guideline followed Not reported Not applicable Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported no data without Positive RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro No guideline followed Not reported Not applicable Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair in vitro mammalian cell transformation assay in vitro No guideline available Not reported Not applicable Acceptable Hamster (as animal) fibroblast Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair in vitro mammalian cell transformation assay in vitro No guideline available Not reported Not applicable Acceptable Hamster (as animal) fibroblast Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation other in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) Not reported Male oral: gavage no data not applicable Positive RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation other in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) Not reported No data oral: gavage no data not applicable Positive RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation other in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) Swiss 18 Male oral: gavage 3.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation other in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) Swiss 18 Male oral: gavage 2.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation other in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) 4 No data oral: unspecified 3.0000000000 D yes not applicable Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable Hamster (as animal) Chinese 12 Male/Female oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable House mouse (as animal) Balb/c Male oral: gavage 32.0000000000 h no data not applicable Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable House mouse (as animal) Balb/c Male oral: gavage 24.0000000000 h no data not applicable Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable House mouse (as animal) Balb/c Male oral: gavage 18.0000000000 h no data not applicable Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo No guideline followed Not reported Not applicable Acceptable House mouse (as animal) Not reported Male Not reported no data not applicable Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo No guideline followed Not reported Not applicable Acceptable Hamster (as animal) Chinese No data Not reported no data not applicable Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No data Acceptable House mouse (as animal) Balb/c No data oral: gavage 18.0000000000 h yes not applicable Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No data Acceptable House mouse (as animal) Balb/c No data oral: gavage 24.0000000000 h yes not applicable Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No data Acceptable House mouse (as animal) Balb/c No data oral: gavage 30.0000000000 h yes not applicable Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable Rat (as animal) Sprague-Dawley 2 Male oral: unspecified 24.0000000000 h yes not applicable Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Sprague-Dawley 4 Male oral: gavage 16.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Sprague-Dawley 4 Male oral: gavage 4.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration dominant lethal assay in vivo No guideline followed Not reported Not applicable Acceptable House mouse (as animal) Tif:MAGf(SPF) 20 Male oral: unspecified yes, concurrent vehicle not applicable Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration dominant lethal assay in vivo No guideline followed Not reported Not applicable Acceptable House mouse (as animal) Not reported Male Not reported no data not applicable Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration dominant lethal assay in vivo According to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) No Acceptable House mouse (as animal) Balb/c Male oral: gavage yes, concurrent vehicle not applicable Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration mammalian germ cell cytogenetic assay in vivo No guideline followed Not reported Not applicable Acceptable House mouse (as animal) NMRI 15 Male oral: gavage 5.0000000000 D yes, concurrent vehicle not applicable Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration mammalian germ cell cytogenetic assay in vivo No guideline followed Not reported Not applicable Acceptable House mouse (as animal) Not reported 15 Male oral: unspecified 3.0000000000 D yes, concurrent vehicle not applicable Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No data Acceptable House mouse (as animal) Not reported No data oral: unspecified 30.0000000000 D no data not applicable Positive RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No data Acceptable House mouse (as animal) Not reported No data oral: unspecified 24.0000000000 h no data not applicable Positive RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian cell micronucleus test in vitro Equivalent or similar to OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test) No data Acceptable Human (as organism) lymphocytes Not reported no data no data Positive RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No data Acceptable Human (as organism) lymphocytes Not reported no data no data Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance 1-(4-isopropylphenyl)-3-methylurea 1-methyl-3-(4-propan-2-ylphenyl)urea Not in list C11H16N2O O=C(Nc1ccc(cc1)C(C)C)NC InChI=1S/C11H16N2O/c1-8(2)9-4-6-10(7-5-9)13-11(14)12-3/h4-8H,1-3H3,(H2,12,13,14) organic compound Other PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance 1-(4-isopropylphenyl)-3-methylurea 1-methyl-3-(4-propan-2-ylphenyl)urea Not in list C11H16N2O O=C(Nc1ccc(cc1)C(C)C)NC InChI=1S/C11H16N2O/c1-8(2)9-4-6-10(7-5-9)13-11(14)12-3/h4-8H,1-3H3,(H2,12,13,14) organic compound Other PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance 1-(4-isopropylphenyl)-3-methylurea 1-methyl-3-(4-propan-2-ylphenyl)urea Not in list C11H16N2O O=C(Nc1ccc(cc1)C(C)C)NC InChI=1S/C11H16N2O/c1-8(2)9-4-6-10(7-5-9)13-11(14)12-3/h4-8H,1-3H3,(H2,12,13,14) organic compound Other PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance 1-(4-isopropylphenyl)-3-methylurea 1-methyl-3-(4-propan-2-ylphenyl)urea Not in list C11H16N2O O=C(Nc1ccc(cc1)C(C)C)NC InChI=1S/C11H16N2O/c1-8(2)9-4-6-10(7-5-9)13-11(14)12-3/h4-8H,1-3H3,(H2,12,13,14) organic compound Other PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance 1-(4-isopropylphenyl)-3-methylurea 1-methyl-3-(4-propan-2-ylphenyl)urea Not in list C11H16N2O O=C(Nc1ccc(cc1)C(C)C)NC InChI=1S/C11H16N2O/c1-8(2)9-4-6-10(7-5-9)13-11(14)12-3/h4-8H,1-3H3,(H2,12,13,14) organic compound Other PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) CM891 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance 1-(4-isopropylphenyl)-3-methylurea 1-methyl-3-(4-propan-2-ylphenyl)urea Not in list C11H16N2O O=C(Nc1ccc(cc1)C(C)C)NC InChI=1S/C11H16N2O/c1-8(2)9-4-6-10(7-5-9)13-11(14)12-3/h4-8H,1-3H3,(H2,12,13,14) organic compound Other PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance 1-(4-isopropylphenyl)-3-methylurea 1-methyl-3-(4-propan-2-ylphenyl)urea Not in list C11H16N2O O=C(Nc1ccc(cc1)C(C)C)NC InChI=1S/C11H16N2O/c1-8(2)9-4-6-10(7-5-9)13-11(14)12-3/h4-8H,1-3H3,(H2,12,13,14) organic compound Other PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance 1-(4-isopropylphenyl)-3-methylurea 1-methyl-3-(4-propan-2-ylphenyl)urea Not in list C11H16N2O O=C(Nc1ccc(cc1)C(C)C)NC InChI=1S/C11H16N2O/c1-8(2)9-4-6-10(7-5-9)13-11(14)12-3/h4-8H,1-3H3,(H2,12,13,14) organic compound Other PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) CM891 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance 1-(4-isopropylphenyl)-3-methylurea 1-methyl-3-(4-propan-2-ylphenyl)urea Not in list C11H16N2O O=C(Nc1ccc(cc1)C(C)C)NC InChI=1S/C11H16N2O/c1-8(2)9-4-6-10(7-5-9)13-11(14)12-3/h4-8H,1-3H3,(H2,12,13,14) organic compound Other PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance 1-(4-isopropylphenyl)-3-methylurea 1-methyl-3-(4-propan-2-ylphenyl)urea Not in list C11H16N2O O=C(Nc1ccc(cc1)C(C)C)NC InChI=1S/C11H16N2O/c1-8(2)9-4-6-10(7-5-9)13-11(14)12-3/h4-8H,1-3H3,(H2,12,13,14) organic compound Other PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is identical to the substance Metsulfuron-methyl 616-063-8 74223-64-6 methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate Metsulfuron-methyl C14H15N5O6S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is identical to the substance Metsulfuron-methyl 616-063-8 74223-64-6 methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate Metsulfuron-methyl C14H15N5O6S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is identical to the substance Metsulfuron-methyl 616-063-8 74223-64-6 methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate Metsulfuron-methyl C14H15N5O6S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is identical to the substance Metsulfuron-methyl 616-063-8 74223-64-6 methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate Metsulfuron-methyl C14H15N5O6S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is identical to the substance Metsulfuron-methyl 616-063-8 74223-64-6 methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate Metsulfuron-methyl C14H15N5O6S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is identical to the substance Metsulfuron-methyl 616-063-8 74223-64-6 methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate Metsulfuron-methyl C14H15N5O6S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is identical to the substance Metsulfuron-methyl 616-063-8 74223-64-6 methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate Metsulfuron-methyl C14H15N5O6S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is identical to the substance Metsulfuron-methyl 616-063-8 74223-64-6 methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate Metsulfuron-methyl C14H15N5O6S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is identical to the substance Metsulfuron-methyl 616-063-8 74223-64-6 methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate Metsulfuron-methyl C14H15N5O6S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is identical to the substance Metsulfuron-methyl 616-063-8 74223-64-6 methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate Metsulfuron-methyl C14H15N5O6S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is identical to the substance Metsulfuron-methyl 616-063-8 74223-64-6 methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate Metsulfuron-methyl C14H15N5O6S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is identical to the substance Metsulfuron-methyl 616-063-8 74223-64-6 methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate Metsulfuron-methyl C14H15N5O6S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is identical to the substance Metsulfuron-methyl 616-063-8 74223-64-6 methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate Metsulfuron-methyl C14H15N5O6S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is identical to the substance Metsulfuron-methyl 616-063-8 74223-64-6 methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate Metsulfuron-methyl C14H15N5O6S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is identical to the substance Metsulfuron-methyl 616-063-8 74223-64-6 methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate Metsulfuron-methyl C14H15N5O6S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is identical to the substance Metsulfuron-methyl 616-063-8 74223-64-6 methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate Metsulfuron-methyl C14H15N5O6S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is identical to the substance Metsulfuron-methyl 616-063-8 74223-64-6 methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate Metsulfuron-methyl C14H15N5O6S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is identical to the substance Metsulfuron-methyl 616-063-8 74223-64-6 methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate Metsulfuron-methyl C14H15N5O6S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is identical to the substance Metsulfuron-methyl 616-063-8 74223-64-6 methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate Metsulfuron-methyl C14H15N5O6S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is identical to the substance Metsulfuron-methyl 616-063-8 74223-64-6 methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate Metsulfuron-methyl C14H15N5O6S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is identical to the substance Metsulfuron-methyl 616-063-8 74223-64-6 methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate Metsulfuron-methyl C14H15N5O6S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is identical to the substance Metsulfuron-methyl 616-063-8 74223-64-6 methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate Metsulfuron-methyl C14H15N5O6S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is identical to the substance Metsulfuron-methyl 616-063-8 74223-64-6 methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate Metsulfuron-methyl C14H15N5O6S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is identical to the substance Metsulfuron-methyl 616-063-8 74223-64-6 methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate Metsulfuron-methyl C14H15N5O6S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is identical to the substance Metsulfuron-methyl 616-063-8 74223-64-6 methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate Metsulfuron-methyl C14H15N5O6S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is identical to the substance Metsulfuron-methyl 616-063-8 74223-64-6 methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate Metsulfuron-methyl C14H15N5O6S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is identical to the substance Metsulfuron-methyl 616-063-8 74223-64-6 methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate Metsulfuron-methyl C14H15N5O6S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is identical to the substance Metsulfuron-methyl 616-063-8 74223-64-6 methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate Metsulfuron-methyl C14H15N5O6S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is identical to the substance Metsulfuron-methyl 616-063-8 74223-64-6 methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate Metsulfuron-methyl C14H15N5O6S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is identical to the substance Metsulfuron-methyl 616-063-8 74223-64-6 methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate Metsulfuron-methyl C14H15N5O6S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is identical to the substance Metsulfuron-methyl 616-063-8 74223-64-6 methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate Metsulfuron-methyl C14H15N5O6S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Positive RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is identical to the substance Metsulfuron-methyl 616-063-8 74223-64-6 methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate Metsulfuron-methyl C14H15N5O6S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Positive RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is identical to the substance Metsulfuron-methyl 616-063-8 74223-64-6 methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate Metsulfuron-methyl C14H15N5O6S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is identical to the substance Metsulfuron-methyl 616-063-8 74223-64-6 methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate Metsulfuron-methyl C14H15N5O6S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is identical to the substance Metsulfuron-methyl 616-063-8 74223-64-6 methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate Metsulfuron-methyl C14H15N5O6S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported no data without Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is identical to the substance Metsulfuron-methyl 616-063-8 74223-64-6 methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate Metsulfuron-methyl C14H15N5O6S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported no data with Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is identical to the substance Metsulfuron-methyl 616-063-8 74223-64-6 methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate Metsulfuron-methyl C14H15N5O6S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Rat (as animal) hepatocytes Not reported no data without Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is identical to the substance Metsulfuron-methyl 616-063-8 74223-64-6 methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate Metsulfuron-methyl C14H15N5O6S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes without Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is identical to the substance Metsulfuron-methyl 616-063-8 74223-64-6 methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate Metsulfuron-methyl C14H15N5O6S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable Rat (as animal) Not reported 10 Male/Female oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is identical to the substance Metsulfuron-methyl 616-063-8 74223-64-6 methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate Metsulfuron-methyl C14H15N5O6S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable Rat (as animal) Not reported 10 Male/Female oral: unspecified 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is identical to the substance Metsulfuron-methyl 616-063-8 74223-64-6 methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate Metsulfuron-methyl C14H15N5O6S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable Rat (as animal) Not reported 10 Male/Female oral: unspecified 72.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is identical to the substance Metsulfuron-methyl 616-063-8 74223-64-6 methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate Metsulfuron-methyl C14H15N5O6S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Sprague-Dawley 40 Male/Female oral: unspecified 48.0000000000 h no data not applicable Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is identical to the substance Metsulfuron-methyl 616-063-8 74223-64-6 methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate Metsulfuron-methyl C14H15N5O6S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Sprague-Dawley 40 Male/Female oral: unspecified 24.0000000000 h no data not applicable Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is identical to the substance Metsulfuron-methyl 616-063-8 74223-64-6 methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate Metsulfuron-methyl C14H15N5O6S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Sprague-Dawley 40 Male/Female oral: unspecified 12.0000000000 h no data not applicable Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is identical to the substance Metsulfuron-methyl 616-063-8 74223-64-6 methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate Metsulfuron-methyl C14H15N5O6S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Sprague-Dawley 40 Male/Female oral: unspecified 6.0000000000 h no data not applicable Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is identical to the substance Metsulfuron-methyl 616-063-8 74223-64-6 methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate Metsulfuron-methyl C14H15N5O6S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Swiss 6 Male oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Inconclusive RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Inconclusive no information RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No data Acceptable Hamster (as animal) Chinese 48 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No data Acceptable Hamster (as animal) Chinese 48 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is a metabolite of the substance 4-methoxy-6-methyl-1,3,5-triazine-2-amine 216-790-7 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine Not in list C5H8N4O CC1=NC(=NC(=N1)OC)N InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No data Acceptable Hamster (as animal) Chinese 48 Male/Female oral: gavage 16.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is a metabolite of the substance methyl 2-(carbamoylsulfamoyl)benzoate methyl 2-(carbamoylsulfamoyl)benzoate Not in list C9H10N2O5S O=S(=O)(NC(N)=O)c1ccccc1C(=O)OC InChI=1S/C9H10N2O5S/c1-16-8(12)6-4-2-3-5-7(6)17(14,15)11-9(10)13/h2-5H,1H3,(H3,10,11,13) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is a metabolite of the substance methyl 2-(carbamoylsulfamoyl)benzoate methyl 2-(carbamoylsulfamoyl)benzoate Not in list C9H10N2O5S O=S(=O)(NC(N)=O)c1ccccc1C(=O)OC InChI=1S/C9H10N2O5S/c1-16-8(12)6-4-2-3-5-7(6)17(14,15)11-9(10)13/h2-5H,1H3,(H3,10,11,13) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is a metabolite of the substance methyl 2-(carbamoylsulfamoyl)benzoate methyl 2-(carbamoylsulfamoyl)benzoate Not in list C9H10N2O5S O=S(=O)(NC(N)=O)c1ccccc1C(=O)OC InChI=1S/C9H10N2O5S/c1-16-8(12)6-4-2-3-5-7(6)17(14,15)11-9(10)13/h2-5H,1H3,(H3,10,11,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is a metabolite of the substance methyl 2-(carbamoylsulfamoyl)benzoate methyl 2-(carbamoylsulfamoyl)benzoate Not in list C9H10N2O5S O=S(=O)(NC(N)=O)c1ccccc1C(=O)OC InChI=1S/C9H10N2O5S/c1-16-8(12)6-4-2-3-5-7(6)17(14,15)11-9(10)13/h2-5H,1H3,(H3,10,11,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is a metabolite of the substance methyl 2-(carbamoylsulfamoyl)benzoate methyl 2-(carbamoylsulfamoyl)benzoate Not in list C9H10N2O5S O=S(=O)(NC(N)=O)c1ccccc1C(=O)OC InChI=1S/C9H10N2O5S/c1-16-8(12)6-4-2-3-5-7(6)17(14,15)11-9(10)13/h2-5H,1H3,(H3,10,11,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is a metabolite of the substance methyl 2-(carbamoylsulfamoyl)benzoate methyl 2-(carbamoylsulfamoyl)benzoate Not in list C9H10N2O5S O=S(=O)(NC(N)=O)c1ccccc1C(=O)OC InChI=1S/C9H10N2O5S/c1-16-8(12)6-4-2-3-5-7(6)17(14,15)11-9(10)13/h2-5H,1H3,(H3,10,11,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is a metabolite of the substance methyl 2-(carbamoylsulfamoyl)benzoate methyl 2-(carbamoylsulfamoyl)benzoate Not in list C9H10N2O5S O=S(=O)(NC(N)=O)c1ccccc1C(=O)OC InChI=1S/C9H10N2O5S/c1-16-8(12)6-4-2-3-5-7(6)17(14,15)11-9(10)13/h2-5H,1H3,(H3,10,11,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is a metabolite of the substance methyl 2-(carbamoylsulfamoyl)benzoate methyl 2-(carbamoylsulfamoyl)benzoate Not in list C9H10N2O5S O=S(=O)(NC(N)=O)c1ccccc1C(=O)OC InChI=1S/C9H10N2O5S/c1-16-8(12)6-4-2-3-5-7(6)17(14,15)11-9(10)13/h2-5H,1H3,(H3,10,11,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is a metabolite of the substance methyl 2-(carbamoylsulfamoyl)benzoate methyl 2-(carbamoylsulfamoyl)benzoate Not in list C9H10N2O5S O=S(=O)(NC(N)=O)c1ccccc1C(=O)OC InChI=1S/C9H10N2O5S/c1-16-8(12)6-4-2-3-5-7(6)17(14,15)11-9(10)13/h2-5H,1H3,(H3,10,11,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is a metabolite of the substance methyl 2-(carbamoylsulfamoyl)benzoate methyl 2-(carbamoylsulfamoyl)benzoate Not in list C9H10N2O5S O=S(=O)(NC(N)=O)c1ccccc1C(=O)OC InChI=1S/C9H10N2O5S/c1-16-8(12)6-4-2-3-5-7(6)17(14,15)11-9(10)13/h2-5H,1H3,(H3,10,11,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is a metabolite of the substance methyl 2-(carbamoylsulfamoyl)benzoate methyl 2-(carbamoylsulfamoyl)benzoate Not in list C9H10N2O5S O=S(=O)(NC(N)=O)c1ccccc1C(=O)OC InChI=1S/C9H10N2O5S/c1-16-8(12)6-4-2-3-5-7(6)17(14,15)11-9(10)13/h2-5H,1H3,(H3,10,11,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is a metabolite of the substance methyl 2-(carbamoylsulfamoyl)benzoate methyl 2-(carbamoylsulfamoyl)benzoate Not in list C9H10N2O5S O=S(=O)(NC(N)=O)c1ccccc1C(=O)OC InChI=1S/C9H10N2O5S/c1-16-8(12)6-4-2-3-5-7(6)17(14,15)11-9(10)13/h2-5H,1H3,(H3,10,11,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is a metabolite of the substance methyl 2-(carbamoylsulfamoyl)benzoate methyl 2-(carbamoylsulfamoyl)benzoate Not in list C9H10N2O5S O=S(=O)(NC(N)=O)c1ccccc1C(=O)OC InChI=1S/C9H10N2O5S/c1-16-8(12)6-4-2-3-5-7(6)17(14,15)11-9(10)13/h2-5H,1H3,(H3,10,11,13) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Positive RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is a metabolite of the substance methyl 2-(carbamoylsulfamoyl)benzoate methyl 2-(carbamoylsulfamoyl)benzoate Not in list C9H10N2O5S O=S(=O)(NC(N)=O)c1ccccc1C(=O)OC InChI=1S/C9H10N2O5S/c1-16-8(12)6-4-2-3-5-7(6)17(14,15)11-9(10)13/h2-5H,1H3,(H3,10,11,13) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Positive RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is a metabolite of the substance methyl 2-(carbamoylsulfamoyl)benzoate methyl 2-(carbamoylsulfamoyl)benzoate Not in list C9H10N2O5S O=S(=O)(NC(N)=O)c1ccccc1C(=O)OC InChI=1S/C9H10N2O5S/c1-16-8(12)6-4-2-3-5-7(6)17(14,15)11-9(10)13/h2-5H,1H3,(H3,10,11,13) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is a metabolite of the substance methyl 2-(carbamoylsulfamoyl)benzoate methyl 2-(carbamoylsulfamoyl)benzoate Not in list C9H10N2O5S O=S(=O)(NC(N)=O)c1ccccc1C(=O)OC InChI=1S/C9H10N2O5S/c1-16-8(12)6-4-2-3-5-7(6)17(14,15)11-9(10)13/h2-5H,1H3,(H3,10,11,13) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is a metabolite of the substance methyl 2-sulfamoylbenzoate methyl 2-sulfamoylbenzoate Not in list C8H9NO4S COC(=O)C1=CC=CC=C1S(=O)(=O)N InChI=1S/C8H9NO4S/c1-13-8(10)6-4-2-3-5-7(6)14(9,11)12/h2-5H,1H3,(H2,9,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is a metabolite of the substance methyl 2-sulfamoylbenzoate methyl 2-sulfamoylbenzoate Not in list C8H9NO4S COC(=O)C1=CC=CC=C1S(=O)(=O)N InChI=1S/C8H9NO4S/c1-13-8(10)6-4-2-3-5-7(6)14(9,11)12/h2-5H,1H3,(H2,9,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is a metabolite of the substance methyl 2-sulfamoylbenzoate methyl 2-sulfamoylbenzoate Not in list C8H9NO4S COC(=O)C1=CC=CC=C1S(=O)(=O)N InChI=1S/C8H9NO4S/c1-13-8(10)6-4-2-3-5-7(6)14(9,11)12/h2-5H,1H3,(H2,9,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is a metabolite of the substance methyl 2-sulfamoylbenzoate methyl 2-sulfamoylbenzoate Not in list C8H9NO4S COC(=O)C1=CC=CC=C1S(=O)(=O)N InChI=1S/C8H9NO4S/c1-13-8(10)6-4-2-3-5-7(6)14(9,11)12/h2-5H,1H3,(H2,9,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is a metabolite of the substance methyl 2-sulfamoylbenzoate methyl 2-sulfamoylbenzoate Not in list C8H9NO4S COC(=O)C1=CC=CC=C1S(=O)(=O)N InChI=1S/C8H9NO4S/c1-13-8(10)6-4-2-3-5-7(6)14(9,11)12/h2-5H,1H3,(H2,9,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is a metabolite of the substance methyl 2-sulfamoylbenzoate methyl 2-sulfamoylbenzoate Not in list C8H9NO4S COC(=O)C1=CC=CC=C1S(=O)(=O)N InChI=1S/C8H9NO4S/c1-13-8(10)6-4-2-3-5-7(6)14(9,11)12/h2-5H,1H3,(H2,9,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is a metabolite of the substance methyl 2-sulfamoylbenzoate methyl 2-sulfamoylbenzoate Not in list C8H9NO4S COC(=O)C1=CC=CC=C1S(=O)(=O)N InChI=1S/C8H9NO4S/c1-13-8(10)6-4-2-3-5-7(6)14(9,11)12/h2-5H,1H3,(H2,9,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is a metabolite of the substance methyl 2-sulfamoylbenzoate methyl 2-sulfamoylbenzoate Not in list C8H9NO4S COC(=O)C1=CC=CC=C1S(=O)(=O)N InChI=1S/C8H9NO4S/c1-13-8(10)6-4-2-3-5-7(6)14(9,11)12/h2-5H,1H3,(H2,9,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Nicosulfuron 111991-09-4 single chemical entity Component is identical to the substance Nicosulfuron 111991-09-4 2-[(4,6-Dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-N,N-dimethylpyridine-3-carboxamide Nicosulfuron C15H18N6O6S CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C15H18N6O6S/c1-21(2)13(22)9-6-5-7-16-12(9)28(24,25)20-15(23)19-14-17-10(26-3)8-11(18-14)27-4/h5-8H,1-4H3,(H2,17,18,19,20,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is identical to the substance Nicosulfuron 111991-09-4 2-[(4,6-Dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-N,N-dimethylpyridine-3-carboxamide Nicosulfuron C15H18N6O6S CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C15H18N6O6S/c1-21(2)13(22)9-6-5-7-16-12(9)28(24,25)20-15(23)19-14-17-10(26-3)8-11(18-14)27-4/h5-8H,1-4H3,(H2,17,18,19,20,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is identical to the substance Nicosulfuron 111991-09-4 2-[(4,6-Dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-N,N-dimethylpyridine-3-carboxamide Nicosulfuron C15H18N6O6S CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C15H18N6O6S/c1-21(2)13(22)9-6-5-7-16-12(9)28(24,25)20-15(23)19-14-17-10(26-3)8-11(18-14)27-4/h5-8H,1-4H3,(H2,17,18,19,20,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is identical to the substance Nicosulfuron 111991-09-4 2-[(4,6-Dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-N,N-dimethylpyridine-3-carboxamide Nicosulfuron C15H18N6O6S CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C15H18N6O6S/c1-21(2)13(22)9-6-5-7-16-12(9)28(24,25)20-15(23)19-14-17-10(26-3)8-11(18-14)27-4/h5-8H,1-4H3,(H2,17,18,19,20,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is identical to the substance Nicosulfuron 111991-09-4 2-[(4,6-Dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-N,N-dimethylpyridine-3-carboxamide Nicosulfuron C15H18N6O6S CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C15H18N6O6S/c1-21(2)13(22)9-6-5-7-16-12(9)28(24,25)20-15(23)19-14-17-10(26-3)8-11(18-14)27-4/h5-8H,1-4H3,(H2,17,18,19,20,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is identical to the substance Nicosulfuron 111991-09-4 2-[(4,6-Dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-N,N-dimethylpyridine-3-carboxamide Nicosulfuron C15H18N6O6S CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C15H18N6O6S/c1-21(2)13(22)9-6-5-7-16-12(9)28(24,25)20-15(23)19-14-17-10(26-3)8-11(18-14)27-4/h5-8H,1-4H3,(H2,17,18,19,20,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is identical to the substance Nicosulfuron 111991-09-4 2-[(4,6-Dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-N,N-dimethylpyridine-3-carboxamide Nicosulfuron C15H18N6O6S CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C15H18N6O6S/c1-21(2)13(22)9-6-5-7-16-12(9)28(24,25)20-15(23)19-14-17-10(26-3)8-11(18-14)27-4/h5-8H,1-4H3,(H2,17,18,19,20,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is identical to the substance Nicosulfuron 111991-09-4 2-[(4,6-Dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-N,N-dimethylpyridine-3-carboxamide Nicosulfuron C15H18N6O6S CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C15H18N6O6S/c1-21(2)13(22)9-6-5-7-16-12(9)28(24,25)20-15(23)19-14-17-10(26-3)8-11(18-14)27-4/h5-8H,1-4H3,(H2,17,18,19,20,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is identical to the substance Nicosulfuron 111991-09-4 2-[(4,6-Dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-N,N-dimethylpyridine-3-carboxamide Nicosulfuron C15H18N6O6S CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C15H18N6O6S/c1-21(2)13(22)9-6-5-7-16-12(9)28(24,25)20-15(23)19-14-17-10(26-3)8-11(18-14)27-4/h5-8H,1-4H3,(H2,17,18,19,20,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is identical to the substance Nicosulfuron 111991-09-4 2-[(4,6-Dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-N,N-dimethylpyridine-3-carboxamide Nicosulfuron C15H18N6O6S CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C15H18N6O6S/c1-21(2)13(22)9-6-5-7-16-12(9)28(24,25)20-15(23)19-14-17-10(26-3)8-11(18-14)27-4/h5-8H,1-4H3,(H2,17,18,19,20,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is identical to the substance Nicosulfuron 111991-09-4 2-[(4,6-Dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-N,N-dimethylpyridine-3-carboxamide Nicosulfuron C15H18N6O6S CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C15H18N6O6S/c1-21(2)13(22)9-6-5-7-16-12(9)28(24,25)20-15(23)19-14-17-10(26-3)8-11(18-14)27-4/h5-8H,1-4H3,(H2,17,18,19,20,23) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is identical to the substance Nicosulfuron 111991-09-4 2-[(4,6-Dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-N,N-dimethylpyridine-3-carboxamide Nicosulfuron C15H18N6O6S CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C15H18N6O6S/c1-21(2)13(22)9-6-5-7-16-12(9)28(24,25)20-15(23)19-14-17-10(26-3)8-11(18-14)27-4/h5-8H,1-4H3,(H2,17,18,19,20,23) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is identical to the substance Nicosulfuron 111991-09-4 2-[(4,6-Dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-N,N-dimethylpyridine-3-carboxamide Nicosulfuron C15H18N6O6S CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C15H18N6O6S/c1-21(2)13(22)9-6-5-7-16-12(9)28(24,25)20-15(23)19-14-17-10(26-3)8-11(18-14)27-4/h5-8H,1-4H3,(H2,17,18,19,20,23) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is identical to the substance Nicosulfuron 111991-09-4 2-[(4,6-Dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-N,N-dimethylpyridine-3-carboxamide Nicosulfuron C15H18N6O6S CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C15H18N6O6S/c1-21(2)13(22)9-6-5-7-16-12(9)28(24,25)20-15(23)19-14-17-10(26-3)8-11(18-14)27-4/h5-8H,1-4H3,(H2,17,18,19,20,23) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is identical to the substance Nicosulfuron 111991-09-4 2-[(4,6-Dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-N,N-dimethylpyridine-3-carboxamide Nicosulfuron C15H18N6O6S CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C15H18N6O6S/c1-21(2)13(22)9-6-5-7-16-12(9)28(24,25)20-15(23)19-14-17-10(26-3)8-11(18-14)27-4/h5-8H,1-4H3,(H2,17,18,19,20,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is identical to the substance Nicosulfuron 111991-09-4 2-[(4,6-Dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-N,N-dimethylpyridine-3-carboxamide Nicosulfuron C15H18N6O6S CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C15H18N6O6S/c1-21(2)13(22)9-6-5-7-16-12(9)28(24,25)20-15(23)19-14-17-10(26-3)8-11(18-14)27-4/h5-8H,1-4H3,(H2,17,18,19,20,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is identical to the substance Nicosulfuron 111991-09-4 2-[(4,6-Dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-N,N-dimethylpyridine-3-carboxamide Nicosulfuron C15H18N6O6S CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C15H18N6O6S/c1-21(2)13(22)9-6-5-7-16-12(9)28(24,25)20-15(23)19-14-17-10(26-3)8-11(18-14)27-4/h5-8H,1-4H3,(H2,17,18,19,20,23) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is identical to the substance Nicosulfuron 111991-09-4 2-[(4,6-Dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-N,N-dimethylpyridine-3-carboxamide Nicosulfuron C15H18N6O6S CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C15H18N6O6S/c1-21(2)13(22)9-6-5-7-16-12(9)28(24,25)20-15(23)19-14-17-10(26-3)8-11(18-14)27-4/h5-8H,1-4H3,(H2,17,18,19,20,23) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is identical to the substance Nicosulfuron 111991-09-4 2-[(4,6-Dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-N,N-dimethylpyridine-3-carboxamide Nicosulfuron C15H18N6O6S CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C15H18N6O6S/c1-21(2)13(22)9-6-5-7-16-12(9)28(24,25)20-15(23)19-14-17-10(26-3)8-11(18-14)27-4/h5-8H,1-4H3,(H2,17,18,19,20,23) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) BDF1 mouse 12 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is identical to the substance Nicosulfuron 111991-09-4 2-[(4,6-Dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-N,N-dimethylpyridine-3-carboxamide Nicosulfuron C15H18N6O6S CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C15H18N6O6S/c1-21(2)13(22)9-6-5-7-16-12(9)28(24,25)20-15(23)19-14-17-10(26-3)8-11(18-14)27-4/h5-8H,1-4H3,(H2,17,18,19,20,23) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) BDF1 mouse 12 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is identical to the substance Nicosulfuron 111991-09-4 2-[(4,6-Dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-N,N-dimethylpyridine-3-carboxamide Nicosulfuron C15H18N6O6S CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C15H18N6O6S/c1-21(2)13(22)9-6-5-7-16-12(9)28(24,25)20-15(23)19-14-17-10(26-3)8-11(18-14)27-4/h5-8H,1-4H3,(H2,17,18,19,20,23) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) BDF1 mouse 12 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is identical to the substance Nicosulfuron 111991-09-4 2-[(4,6-Dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-N,N-dimethylpyridine-3-carboxamide Nicosulfuron C15H18N6O6S CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C15H18N6O6S/c1-21(2)13(22)9-6-5-7-16-12(9)28(24,25)20-15(23)19-14-17-10(26-3)8-11(18-14)27-4/h5-8H,1-4H3,(H2,17,18,19,20,23) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) BDF1 mouse 12 Male/Female oral: gavage 72.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is identical to the substance Nicosulfuron 111991-09-4 2-[(4,6-Dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-N,N-dimethylpyridine-3-carboxamide Nicosulfuron C15H18N6O6S CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C15H18N6O6S/c1-21(2)13(22)9-6-5-7-16-12(9)28(24,25)20-15(23)19-14-17-10(26-3)8-11(18-14)27-4/h5-8H,1-4H3,(H2,17,18,19,20,23) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Crj:CD(SD) 4 Male oral: gavage 2.0000000000 h yes not applicable Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is identical to the substance Nicosulfuron 111991-09-4 2-[(4,6-Dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-N,N-dimethylpyridine-3-carboxamide Nicosulfuron C15H18N6O6S CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C15H18N6O6S/c1-21(2)13(22)9-6-5-7-16-12(9)28(24,25)20-15(23)19-14-17-10(26-3)8-11(18-14)27-4/h5-8H,1-4H3,(H2,17,18,19,20,23) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Crj:CD(SD) 4 Male oral: gavage 16.0000000000 h yes not applicable Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide Not in list C8H11N3O3S CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)N InChI=1S/C8H11N3O3S/c1-11(2)8(12)6-4-3-5-10-7(6)15(9,13)14/h3-5H,1-2H3,(H2,9,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide Not in list C8H11N3O3S CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)N InChI=1S/C8H11N3O3S/c1-11(2)8(12)6-4-3-5-10-7(6)15(9,13)14/h3-5H,1-2H3,(H2,9,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide Not in list C8H11N3O3S CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)N InChI=1S/C8H11N3O3S/c1-11(2)8(12)6-4-3-5-10-7(6)15(9,13)14/h3-5H,1-2H3,(H2,9,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide Not in list C8H11N3O3S CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)N InChI=1S/C8H11N3O3S/c1-11(2)8(12)6-4-3-5-10-7(6)15(9,13)14/h3-5H,1-2H3,(H2,9,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide Not in list C8H11N3O3S CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)N InChI=1S/C8H11N3O3S/c1-11(2)8(12)6-4-3-5-10-7(6)15(9,13)14/h3-5H,1-2H3,(H2,9,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide Not in list C8H11N3O3S CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)N InChI=1S/C8H11N3O3S/c1-11(2)8(12)6-4-3-5-10-7(6)15(9,13)14/h3-5H,1-2H3,(H2,9,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide Not in list C8H11N3O3S CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)N InChI=1S/C8H11N3O3S/c1-11(2)8(12)6-4-3-5-10-7(6)15(9,13)14/h3-5H,1-2H3,(H2,9,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide Not in list C8H11N3O3S CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)N InChI=1S/C8H11N3O3S/c1-11(2)8(12)6-4-3-5-10-7(6)15(9,13)14/h3-5H,1-2H3,(H2,9,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide Not in list C8H11N3O3S CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)N InChI=1S/C8H11N3O3S/c1-11(2)8(12)6-4-3-5-10-7(6)15(9,13)14/h3-5H,1-2H3,(H2,9,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide Not in list C8H11N3O3S CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)N InChI=1S/C8H11N3O3S/c1-11(2)8(12)6-4-3-5-10-7(6)15(9,13)14/h3-5H,1-2H3,(H2,9,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide Not in list C8H11N3O3S CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)N InChI=1S/C8H11N3O3S/c1-11(2)8(12)6-4-3-5-10-7(6)15(9,13)14/h3-5H,1-2H3,(H2,9,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide Not in list C8H11N3O3S CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)N InChI=1S/C8H11N3O3S/c1-11(2)8(12)6-4-3-5-10-7(6)15(9,13)14/h3-5H,1-2H3,(H2,9,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide Not in list C8H11N3O3S CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)N InChI=1S/C8H11N3O3S/c1-11(2)8(12)6-4-3-5-10-7(6)15(9,13)14/h3-5H,1-2H3,(H2,9,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide Not in list C8H11N3O3S CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)N InChI=1S/C8H11N3O3S/c1-11(2)8(12)6-4-3-5-10-7(6)15(9,13)14/h3-5H,1-2H3,(H2,9,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide Not in list C8H11N3O3S CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)N InChI=1S/C8H11N3O3S/c1-11(2)8(12)6-4-3-5-10-7(6)15(9,13)14/h3-5H,1-2H3,(H2,9,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide Not in list C8H11N3O3S CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)N InChI=1S/C8H11N3O3S/c1-11(2)8(12)6-4-3-5-10-7(6)15(9,13)14/h3-5H,1-2H3,(H2,9,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide Not in list C8H11N3O3S CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)N InChI=1S/C8H11N3O3S/c1-11(2)8(12)6-4-3-5-10-7(6)15(9,13)14/h3-5H,1-2H3,(H2,9,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide Not in list C8H11N3O3S CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)N InChI=1S/C8H11N3O3S/c1-11(2)8(12)6-4-3-5-10-7(6)15(9,13)14/h3-5H,1-2H3,(H2,9,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide Not in list C8H11N3O3S CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)N InChI=1S/C8H11N3O3S/c1-11(2)8(12)6-4-3-5-10-7(6)15(9,13)14/h3-5H,1-2H3,(H2,9,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative large colonies RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide Not in list C8H11N3O3S CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)N InChI=1S/C8H11N3O3S/c1-11(2)8(12)6-4-3-5-10-7(6)15(9,13)14/h3-5H,1-2H3,(H2,9,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative small colonies RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide Not in list C8H11N3O3S CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)N InChI=1S/C8H11N3O3S/c1-11(2)8(12)6-4-3-5-10-7(6)15(9,13)14/h3-5H,1-2H3,(H2,9,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative small colonies RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide Not in list C8H11N3O3S CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)N InChI=1S/C8H11N3O3S/c1-11(2)8(12)6-4-3-5-10-7(6)15(9,13)14/h3-5H,1-2H3,(H2,9,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative large colonies RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide Not in list C8H11N3O3S CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)N InChI=1S/C8H11N3O3S/c1-11(2)8(12)6-4-3-5-10-7(6)15(9,13)14/h3-5H,1-2H3,(H2,9,13,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Positive RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide Not in list C8H11N3O3S CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)N InChI=1S/C8H11N3O3S/c1-11(2)8(12)6-4-3-5-10-7(6)15(9,13)14/h3-5H,1-2H3,(H2,9,13,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Positive RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide Not in list C8H11N3O3S CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)N InChI=1S/C8H11N3O3S/c1-11(2)8(12)6-4-3-5-10-7(6)15(9,13)14/h3-5H,1-2H3,(H2,9,13,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female intraperitoneal 24.0000000000 h yes not applicable Negative indirect evidence-systemic toxicity RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide Not in list C8H11N3O3S CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)N InChI=1S/C8H11N3O3S/c1-11(2)8(12)6-4-3-5-10-7(6)15(9,13)14/h3-5H,1-2H3,(H2,9,13,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female intraperitoneal 72.0000000000 h yes not applicable Negative indirect evidence-systemic toxicity RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide Not in list C8H11N3O3S CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)N InChI=1S/C8H11N3O3S/c1-11(2)8(12)6-4-3-5-10-7(6)15(9,13)14/h3-5H,1-2H3,(H2,9,13,14) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female intraperitoneal 48.0000000000 h yes not applicable Negative indirect evidence-systemic toxicity RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance 2-Amino-4,6-dimethoxypyrimidine 252-969-6 36315-01-2 4,6-Dimethoxypyrimidin-2-amine Not in list C6H9N3O2 COC1=CC(=NC(=N1)N)OC InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance 2-Amino-4,6-dimethoxypyrimidine 252-969-6 36315-01-2 4,6-Dimethoxypyrimidin-2-amine Not in list C6H9N3O2 COC1=CC(=NC(=N1)N)OC InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance 2-Amino-4,6-dimethoxypyrimidine 252-969-6 36315-01-2 4,6-Dimethoxypyrimidin-2-amine Not in list C6H9N3O2 COC1=CC(=NC(=N1)N)OC InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance 2-Amino-4,6-dimethoxypyrimidine 252-969-6 36315-01-2 4,6-Dimethoxypyrimidin-2-amine Not in list C6H9N3O2 COC1=CC(=NC(=N1)N)OC InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance 2-Amino-4,6-dimethoxypyrimidine 252-969-6 36315-01-2 4,6-Dimethoxypyrimidin-2-amine Not in list C6H9N3O2 COC1=CC(=NC(=N1)N)OC InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance 2-Amino-4,6-dimethoxypyrimidine 252-969-6 36315-01-2 4,6-Dimethoxypyrimidin-2-amine Not in list C6H9N3O2 COC1=CC(=NC(=N1)N)OC InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance 2-Amino-4,6-dimethoxypyrimidine 252-969-6 36315-01-2 4,6-Dimethoxypyrimidin-2-amine Not in list C6H9N3O2 COC1=CC(=NC(=N1)N)OC InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance 2-Amino-4,6-dimethoxypyrimidine 252-969-6 36315-01-2 4,6-Dimethoxypyrimidin-2-amine Not in list C6H9N3O2 COC1=CC(=NC(=N1)N)OC InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance 2-Amino-4,6-dimethoxypyrimidine 252-969-6 36315-01-2 4,6-Dimethoxypyrimidin-2-amine Not in list C6H9N3O2 COC1=CC(=NC(=N1)N)OC InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance 2-Amino-4,6-dimethoxypyrimidine 252-969-6 36315-01-2 4,6-Dimethoxypyrimidin-2-amine Not in list C6H9N3O2 COC1=CC(=NC(=N1)N)OC InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance 2-[(Carbamimidoylcarbamoyl)sulfamoyl]-N,Ndimethylpyridine-3-carboxamide 2-[(carbamimidoylcarbamoyl)sulfamoyl]-N,N-dimethylpyridine-3-carboxamide Not in list C10H14N6O4S O=S(=O)(NC(=O)NC(=N)N)c1ncccc1C(=O)N(C)C InChI=1S/C10H14N6O4S/c1-16(2)8(17)6-4-3-5-13-7(6)21(19,20)15-10(18)14-9(11)12/h3-5H,1-2H3,(H5,11,12,14,15,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance 2-[(Carbamimidoylcarbamoyl)sulfamoyl]-N,Ndimethylpyridine-3-carboxamide 2-[(carbamimidoylcarbamoyl)sulfamoyl]-N,N-dimethylpyridine-3-carboxamide Not in list C10H14N6O4S O=S(=O)(NC(=O)NC(=N)N)c1ncccc1C(=O)N(C)C InChI=1S/C10H14N6O4S/c1-16(2)8(17)6-4-3-5-13-7(6)21(19,20)15-10(18)14-9(11)12/h3-5H,1-2H3,(H5,11,12,14,15,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance 2-[(Carbamimidoylcarbamoyl)sulfamoyl]-N,Ndimethylpyridine-3-carboxamide 2-[(carbamimidoylcarbamoyl)sulfamoyl]-N,N-dimethylpyridine-3-carboxamide Not in list C10H14N6O4S O=S(=O)(NC(=O)NC(=N)N)c1ncccc1C(=O)N(C)C InChI=1S/C10H14N6O4S/c1-16(2)8(17)6-4-3-5-13-7(6)21(19,20)15-10(18)14-9(11)12/h3-5H,1-2H3,(H5,11,12,14,15,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance 2-[(Carbamimidoylcarbamoyl)sulfamoyl]-N,Ndimethylpyridine-3-carboxamide 2-[(carbamimidoylcarbamoyl)sulfamoyl]-N,N-dimethylpyridine-3-carboxamide Not in list C10H14N6O4S O=S(=O)(NC(=O)NC(=N)N)c1ncccc1C(=O)N(C)C InChI=1S/C10H14N6O4S/c1-16(2)8(17)6-4-3-5-13-7(6)21(19,20)15-10(18)14-9(11)12/h3-5H,1-2H3,(H5,11,12,14,15,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance 2-[(Carbamimidoylcarbamoyl)sulfamoyl]-N,Ndimethylpyridine-3-carboxamide 2-[(carbamimidoylcarbamoyl)sulfamoyl]-N,N-dimethylpyridine-3-carboxamide Not in list C10H14N6O4S O=S(=O)(NC(=O)NC(=N)N)c1ncccc1C(=O)N(C)C InChI=1S/C10H14N6O4S/c1-16(2)8(17)6-4-3-5-13-7(6)21(19,20)15-10(18)14-9(11)12/h3-5H,1-2H3,(H5,11,12,14,15,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance 2-[(Carbamimidoylcarbamoyl)sulfamoyl]-N,Ndimethylpyridine-3-carboxamide 2-[(carbamimidoylcarbamoyl)sulfamoyl]-N,N-dimethylpyridine-3-carboxamide Not in list C10H14N6O4S O=S(=O)(NC(=O)NC(=N)N)c1ncccc1C(=O)N(C)C InChI=1S/C10H14N6O4S/c1-16(2)8(17)6-4-3-5-13-7(6)21(19,20)15-10(18)14-9(11)12/h3-5H,1-2H3,(H5,11,12,14,15,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance 2-[(Carbamimidoylcarbamoyl)sulfamoyl]-N,Ndimethylpyridine-3-carboxamide 2-[(carbamimidoylcarbamoyl)sulfamoyl]-N,N-dimethylpyridine-3-carboxamide Not in list C10H14N6O4S O=S(=O)(NC(=O)NC(=N)N)c1ncccc1C(=O)N(C)C InChI=1S/C10H14N6O4S/c1-16(2)8(17)6-4-3-5-13-7(6)21(19,20)15-10(18)14-9(11)12/h3-5H,1-2H3,(H5,11,12,14,15,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance 2-[(Carbamimidoylcarbamoyl)sulfamoyl]-N,Ndimethylpyridine-3-carboxamide 2-[(carbamimidoylcarbamoyl)sulfamoyl]-N,N-dimethylpyridine-3-carboxamide Not in list C10H14N6O4S O=S(=O)(NC(=O)NC(=N)N)c1ncccc1C(=O)N(C)C InChI=1S/C10H14N6O4S/c1-16(2)8(17)6-4-3-5-13-7(6)21(19,20)15-10(18)14-9(11)12/h3-5H,1-2H3,(H5,11,12,14,15,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance 2-[(Carbamimidoylcarbamoyl)sulfamoyl]-N,Ndimethylpyridine-3-carboxamide 2-[(carbamimidoylcarbamoyl)sulfamoyl]-N,N-dimethylpyridine-3-carboxamide Not in list C10H14N6O4S O=S(=O)(NC(=O)NC(=N)N)c1ncccc1C(=O)N(C)C InChI=1S/C10H14N6O4S/c1-16(2)8(17)6-4-3-5-13-7(6)21(19,20)15-10(18)14-9(11)12/h3-5H,1-2H3,(H5,11,12,14,15,18) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative small colonies RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance 2-[(Carbamimidoylcarbamoyl)sulfamoyl]-N,Ndimethylpyridine-3-carboxamide 2-[(carbamimidoylcarbamoyl)sulfamoyl]-N,N-dimethylpyridine-3-carboxamide Not in list C10H14N6O4S O=S(=O)(NC(=O)NC(=N)N)c1ncccc1C(=O)N(C)C InChI=1S/C10H14N6O4S/c1-16(2)8(17)6-4-3-5-13-7(6)21(19,20)15-10(18)14-9(11)12/h3-5H,1-2H3,(H5,11,12,14,15,18) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative large colonies RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance 2-[(Carbamimidoylcarbamoyl)sulfamoyl]-N,Ndimethylpyridine-3-carboxamide 2-[(carbamimidoylcarbamoyl)sulfamoyl]-N,N-dimethylpyridine-3-carboxamide Not in list C10H14N6O4S O=S(=O)(NC(=O)NC(=N)N)c1ncccc1C(=O)N(C)C InChI=1S/C10H14N6O4S/c1-16(2)8(17)6-4-3-5-13-7(6)21(19,20)15-10(18)14-9(11)12/h3-5H,1-2H3,(H5,11,12,14,15,18) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative small colonies RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance 2-[(Carbamimidoylcarbamoyl)sulfamoyl]-N,Ndimethylpyridine-3-carboxamide 2-[(carbamimidoylcarbamoyl)sulfamoyl]-N,N-dimethylpyridine-3-carboxamide Not in list C10H14N6O4S O=S(=O)(NC(=O)NC(=N)N)c1ncccc1C(=O)N(C)C InChI=1S/C10H14N6O4S/c1-16(2)8(17)6-4-3-5-13-7(6)21(19,20)15-10(18)14-9(11)12/h3-5H,1-2H3,(H5,11,12,14,15,18) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative large colonies RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance 2-[(Carbamimidoylcarbamoyl)sulfamoyl]-N,Ndimethylpyridine-3-carboxamide 2-[(carbamimidoylcarbamoyl)sulfamoyl]-N,N-dimethylpyridine-3-carboxamide Not in list C10H14N6O4S O=S(=O)(NC(=O)NC(=N)N)c1ncccc1C(=O)N(C)C InChI=1S/C10H14N6O4S/c1-16(2)8(17)6-4-3-5-13-7(6)21(19,20)15-10(18)14-9(11)12/h3-5H,1-2H3,(H5,11,12,14,15,18) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance 2-[(Carbamimidoylcarbamoyl)sulfamoyl]-N,Ndimethylpyridine-3-carboxamide 2-[(carbamimidoylcarbamoyl)sulfamoyl]-N,N-dimethylpyridine-3-carboxamide Not in list C10H14N6O4S O=S(=O)(NC(=O)NC(=N)N)c1ncccc1C(=O)N(C)C InChI=1S/C10H14N6O4S/c1-16(2)8(17)6-4-3-5-13-7(6)21(19,20)15-10(18)14-9(11)12/h3-5H,1-2H3,(H5,11,12,14,15,18) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance 2-[(Carbamoylcarbamoyl)sulfamoyl]-N,Ndimethylpyridine-3-carboxamide 2-[(carbamoylcarbamoyl)sulfamoyl]-N,N-dimethylpyridine-3-carboxamide Not in list C10H13N5O5S O=S(=O)(NC(=O)NC(N)=O)c1ncccc1C(=O)N(C)C InChI=1S/C10H13N5O5S/c1-15(2)8(16)6-4-3-5-12-7(6)21(19,20)14-10(18)13-9(11)17/h3-5H,1-2H3,(H4,11,13,14,17,18) metal compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance 2-[(Carbamoylcarbamoyl)sulfamoyl]-N,Ndimethylpyridine-3-carboxamide 2-[(carbamoylcarbamoyl)sulfamoyl]-N,N-dimethylpyridine-3-carboxamide Not in list C10H13N5O5S O=S(=O)(NC(=O)NC(N)=O)c1ncccc1C(=O)N(C)C InChI=1S/C10H13N5O5S/c1-15(2)8(16)6-4-3-5-12-7(6)21(19,20)14-10(18)13-9(11)17/h3-5H,1-2H3,(H4,11,13,14,17,18) metal compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance 2-[(Carbamoylcarbamoyl)sulfamoyl]-N,Ndimethylpyridine-3-carboxamide 2-[(carbamoylcarbamoyl)sulfamoyl]-N,N-dimethylpyridine-3-carboxamide Not in list C10H13N5O5S O=S(=O)(NC(=O)NC(N)=O)c1ncccc1C(=O)N(C)C InChI=1S/C10H13N5O5S/c1-15(2)8(16)6-4-3-5-12-7(6)21(19,20)14-10(18)13-9(11)17/h3-5H,1-2H3,(H4,11,13,14,17,18) metal compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance 2-[(Carbamoylcarbamoyl)sulfamoyl]-N,Ndimethylpyridine-3-carboxamide 2-[(carbamoylcarbamoyl)sulfamoyl]-N,N-dimethylpyridine-3-carboxamide Not in list C10H13N5O5S O=S(=O)(NC(=O)NC(N)=O)c1ncccc1C(=O)N(C)C InChI=1S/C10H13N5O5S/c1-15(2)8(16)6-4-3-5-12-7(6)21(19,20)14-10(18)13-9(11)17/h3-5H,1-2H3,(H4,11,13,14,17,18) metal compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance 2-[(Carbamoylcarbamoyl)sulfamoyl]-N,Ndimethylpyridine-3-carboxamide 2-[(carbamoylcarbamoyl)sulfamoyl]-N,N-dimethylpyridine-3-carboxamide Not in list C10H13N5O5S O=S(=O)(NC(=O)NC(N)=O)c1ncccc1C(=O)N(C)C InChI=1S/C10H13N5O5S/c1-15(2)8(16)6-4-3-5-12-7(6)21(19,20)14-10(18)13-9(11)17/h3-5H,1-2H3,(H4,11,13,14,17,18) metal compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance 2-[(Carbamoylcarbamoyl)sulfamoyl]-N,Ndimethylpyridine-3-carboxamide 2-[(carbamoylcarbamoyl)sulfamoyl]-N,N-dimethylpyridine-3-carboxamide Not in list C10H13N5O5S O=S(=O)(NC(=O)NC(N)=O)c1ncccc1C(=O)N(C)C InChI=1S/C10H13N5O5S/c1-15(2)8(16)6-4-3-5-12-7(6)21(19,20)14-10(18)13-9(11)17/h3-5H,1-2H3,(H4,11,13,14,17,18) metal compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance 2-[(Carbamoylcarbamoyl)sulfamoyl]-N,Ndimethylpyridine-3-carboxamide 2-[(carbamoylcarbamoyl)sulfamoyl]-N,N-dimethylpyridine-3-carboxamide Not in list C10H13N5O5S O=S(=O)(NC(=O)NC(N)=O)c1ncccc1C(=O)N(C)C InChI=1S/C10H13N5O5S/c1-15(2)8(16)6-4-3-5-12-7(6)21(19,20)14-10(18)13-9(11)17/h3-5H,1-2H3,(H4,11,13,14,17,18) metal compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance 2-[(Carbamoylcarbamoyl)sulfamoyl]-N,Ndimethylpyridine-3-carboxamide 2-[(carbamoylcarbamoyl)sulfamoyl]-N,N-dimethylpyridine-3-carboxamide Not in list C10H13N5O5S O=S(=O)(NC(=O)NC(N)=O)c1ncccc1C(=O)N(C)C InChI=1S/C10H13N5O5S/c1-15(2)8(16)6-4-3-5-12-7(6)21(19,20)14-10(18)13-9(11)17/h3-5H,1-2H3,(H4,11,13,14,17,18) metal compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance 2-[(Carbamoylcarbamoyl)sulfamoyl]-N,Ndimethylpyridine-3-carboxamide 2-[(carbamoylcarbamoyl)sulfamoyl]-N,N-dimethylpyridine-3-carboxamide Not in list C10H13N5O5S O=S(=O)(NC(=O)NC(N)=O)c1ncccc1C(=O)N(C)C InChI=1S/C10H13N5O5S/c1-15(2)8(16)6-4-3-5-12-7(6)21(19,20)14-10(18)13-9(11)17/h3-5H,1-2H3,(H4,11,13,14,17,18) metal compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative small colonies RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance 2-[(Carbamoylcarbamoyl)sulfamoyl]-N,Ndimethylpyridine-3-carboxamide 2-[(carbamoylcarbamoyl)sulfamoyl]-N,N-dimethylpyridine-3-carboxamide Not in list C10H13N5O5S O=S(=O)(NC(=O)NC(N)=O)c1ncccc1C(=O)N(C)C InChI=1S/C10H13N5O5S/c1-15(2)8(16)6-4-3-5-12-7(6)21(19,20)14-10(18)13-9(11)17/h3-5H,1-2H3,(H4,11,13,14,17,18) metal compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative large colonies RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance 2-[(Carbamoylcarbamoyl)sulfamoyl]-N,Ndimethylpyridine-3-carboxamide 2-[(carbamoylcarbamoyl)sulfamoyl]-N,N-dimethylpyridine-3-carboxamide Not in list C10H13N5O5S O=S(=O)(NC(=O)NC(N)=O)c1ncccc1C(=O)N(C)C InChI=1S/C10H13N5O5S/c1-15(2)8(16)6-4-3-5-12-7(6)21(19,20)14-10(18)13-9(11)17/h3-5H,1-2H3,(H4,11,13,14,17,18) metal compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Negative small colonies RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance 2-[(Carbamoylcarbamoyl)sulfamoyl]-N,Ndimethylpyridine-3-carboxamide 2-[(carbamoylcarbamoyl)sulfamoyl]-N,N-dimethylpyridine-3-carboxamide Not in list C10H13N5O5S O=S(=O)(NC(=O)NC(N)=O)c1ncccc1C(=O)N(C)C InChI=1S/C10H13N5O5S/c1-15(2)8(16)6-4-3-5-12-7(6)21(19,20)14-10(18)13-9(11)17/h3-5H,1-2H3,(H4,11,13,14,17,18) metal compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Negative large colonies RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance 2-[(Carbamoylcarbamoyl)sulfamoyl]-N,Ndimethylpyridine-3-carboxamide 2-[(carbamoylcarbamoyl)sulfamoyl]-N,N-dimethylpyridine-3-carboxamide Not in list C10H13N5O5S O=S(=O)(NC(=O)NC(N)=O)c1ncccc1C(=O)N(C)C InChI=1S/C10H13N5O5S/c1-15(2)8(16)6-4-3-5-12-7(6)21(19,20)14-10(18)13-9(11)17/h3-5H,1-2H3,(H4,11,13,14,17,18) metal compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance 2-[(Carbamoylcarbamoyl)sulfamoyl]-N,Ndimethylpyridine-3-carboxamide 2-[(carbamoylcarbamoyl)sulfamoyl]-N,N-dimethylpyridine-3-carboxamide Not in list C10H13N5O5S O=S(=O)(NC(=O)NC(N)=O)c1ncccc1C(=O)N(C)C InChI=1S/C10H13N5O5S/c1-15(2)8(16)6-4-3-5-12-7(6)21(19,20)14-10(18)13-9(11)17/h3-5H,1-2H3,(H4,11,13,14,17,18) metal compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance N-methyl-2-sulfamoylpyridine-3-carboxamide N-methyl-2-sulfamoylpyridine-3-carboxamide Not in list C7H9N3O3S CNC(=O)C1=C(N=CC=C1)S(=O)(=O)N InChI=1S/C7H9N3O3S/c1-9-6(11)5-3-2-4-10-7(5)14(8,12)13/h2-4H,1H3,(H,9,11)(H2,8,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance N-methyl-2-sulfamoylpyridine-3-carboxamide N-methyl-2-sulfamoylpyridine-3-carboxamide Not in list C7H9N3O3S CNC(=O)C1=C(N=CC=C1)S(=O)(=O)N InChI=1S/C7H9N3O3S/c1-9-6(11)5-3-2-4-10-7(5)14(8,12)13/h2-4H,1H3,(H,9,11)(H2,8,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance N-methyl-2-sulfamoylpyridine-3-carboxamide N-methyl-2-sulfamoylpyridine-3-carboxamide Not in list C7H9N3O3S CNC(=O)C1=C(N=CC=C1)S(=O)(=O)N InChI=1S/C7H9N3O3S/c1-9-6(11)5-3-2-4-10-7(5)14(8,12)13/h2-4H,1H3,(H,9,11)(H2,8,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance N-methyl-2-sulfamoylpyridine-3-carboxamide N-methyl-2-sulfamoylpyridine-3-carboxamide Not in list C7H9N3O3S CNC(=O)C1=C(N=CC=C1)S(=O)(=O)N InChI=1S/C7H9N3O3S/c1-9-6(11)5-3-2-4-10-7(5)14(8,12)13/h2-4H,1H3,(H,9,11)(H2,8,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance N-methyl-2-sulfamoylpyridine-3-carboxamide N-methyl-2-sulfamoylpyridine-3-carboxamide Not in list C7H9N3O3S CNC(=O)C1=C(N=CC=C1)S(=O)(=O)N InChI=1S/C7H9N3O3S/c1-9-6(11)5-3-2-4-10-7(5)14(8,12)13/h2-4H,1H3,(H,9,11)(H2,8,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance N-methyl-2-sulfamoylpyridine-3-carboxamide N-methyl-2-sulfamoylpyridine-3-carboxamide Not in list C7H9N3O3S CNC(=O)C1=C(N=CC=C1)S(=O)(=O)N InChI=1S/C7H9N3O3S/c1-9-6(11)5-3-2-4-10-7(5)14(8,12)13/h2-4H,1H3,(H,9,11)(H2,8,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance N-methyl-2-sulfamoylpyridine-3-carboxamide N-methyl-2-sulfamoylpyridine-3-carboxamide Not in list C7H9N3O3S CNC(=O)C1=C(N=CC=C1)S(=O)(=O)N InChI=1S/C7H9N3O3S/c1-9-6(11)5-3-2-4-10-7(5)14(8,12)13/h2-4H,1H3,(H,9,11)(H2,8,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance N-methyl-2-sulfamoylpyridine-3-carboxamide N-methyl-2-sulfamoylpyridine-3-carboxamide Not in list C7H9N3O3S CNC(=O)C1=C(N=CC=C1)S(=O)(=O)N InChI=1S/C7H9N3O3S/c1-9-6(11)5-3-2-4-10-7(5)14(8,12)13/h2-4H,1H3,(H,9,11)(H2,8,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance N-methyl-2-sulfamoylpyridine-3-carboxamide N-methyl-2-sulfamoylpyridine-3-carboxamide Not in list C7H9N3O3S CNC(=O)C1=C(N=CC=C1)S(=O)(=O)N InChI=1S/C7H9N3O3S/c1-9-6(11)5-3-2-4-10-7(5)14(8,12)13/h2-4H,1H3,(H,9,11)(H2,8,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Negative large colonies RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance N-methyl-2-sulfamoylpyridine-3-carboxamide N-methyl-2-sulfamoylpyridine-3-carboxamide Not in list C7H9N3O3S CNC(=O)C1=C(N=CC=C1)S(=O)(=O)N InChI=1S/C7H9N3O3S/c1-9-6(11)5-3-2-4-10-7(5)14(8,12)13/h2-4H,1H3,(H,9,11)(H2,8,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative small colonies RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance N-methyl-2-sulfamoylpyridine-3-carboxamide N-methyl-2-sulfamoylpyridine-3-carboxamide Not in list C7H9N3O3S CNC(=O)C1=C(N=CC=C1)S(=O)(=O)N InChI=1S/C7H9N3O3S/c1-9-6(11)5-3-2-4-10-7(5)14(8,12)13/h2-4H,1H3,(H,9,11)(H2,8,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Negative small colonies RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance N-methyl-2-sulfamoylpyridine-3-carboxamide N-methyl-2-sulfamoylpyridine-3-carboxamide Not in list C7H9N3O3S CNC(=O)C1=C(N=CC=C1)S(=O)(=O)N InChI=1S/C7H9N3O3S/c1-9-6(11)5-3-2-4-10-7(5)14(8,12)13/h2-4H,1H3,(H,9,11)(H2,8,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative large colonies RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance N-methyl-2-sulfamoylpyridine-3-carboxamide N-methyl-2-sulfamoylpyridine-3-carboxamide Not in list C7H9N3O3S CNC(=O)C1=C(N=CC=C1)S(=O)(=O)N InChI=1S/C7H9N3O3S/c1-9-6(11)5-3-2-4-10-7(5)14(8,12)13/h2-4H,1H3,(H,9,11)(H2,8,12,13) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance N-methyl-2-sulfamoylpyridine-3-carboxamide N-methyl-2-sulfamoylpyridine-3-carboxamide Not in list C7H9N3O3S CNC(=O)C1=C(N=CC=C1)S(=O)(=O)N InChI=1S/C7H9N3O3S/c1-9-6(11)5-3-2-4-10-7(5)14(8,12)13/h2-4H,1H3,(H,9,11)(H2,8,12,13) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 mixture or formulation Component is part of a group assessment Nicosulfuron leachate (lysimeter product) Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 mixture or formulation Component is part of a group assessment Nicosulfuron leachate (lysimeter product) Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 mixture or formulation Component is part of a group assessment Nicosulfuron leachate (lysimeter product) Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 mixture or formulation Component is part of a group assessment Nicosulfuron leachate (lysimeter product) Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 mixture or formulation Component is part of a group assessment Nicosulfuron leachate (lysimeter product) Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 mixture or formulation Component is part of a group assessment Nicosulfuron leachate (lysimeter product) Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 mixture or formulation Component is part of a group assessment Nicosulfuron leachate (lysimeter product) Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 mixture or formulation Component is part of a group assessment Nicosulfuron leachate (lysimeter product) Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The United Kingdom Nicosulfuron 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance 2-{[(4-Hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,Ndimethylpyridine-3-carboxamide 2-{[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,N-dimethylpyridine-3-carboxamide Not in list C14H16N6O6S O=S(=O)(NC(=O)Nc1nc(O)cc(OC)n1)c2ncccc2C(=O)N(C)C InChI=1S/C14H16N6O6S/c1-20(2)12(22)8-5-4-6-15-11(8)27(24,25)19-14(23)18-13-16-9(21)7-10(17-13)26-3/h4-7H,1-3H3,(H3,16,17,18,19,21,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Nicosulfuron (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance 2-{[(4-Hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,Ndimethylpyridine-3-carboxamide 2-{[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,N-dimethylpyridine-3-carboxamide Not in list C14H16N6O6S O=S(=O)(NC(=O)Nc1nc(O)cc(OC)n1)c2ncccc2C(=O)N(C)C InChI=1S/C14H16N6O6S/c1-20(2)12(22)8-5-4-6-15-11(8)27(24,25)19-14(23)18-13-16-9(21)7-10(17-13)26-3/h4-7H,1-3H3,(H3,16,17,18,19,21,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Nicosulfuron (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance 2-{[(4-Hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,Ndimethylpyridine-3-carboxamide 2-{[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,N-dimethylpyridine-3-carboxamide Not in list C14H16N6O6S O=S(=O)(NC(=O)Nc1nc(O)cc(OC)n1)c2ncccc2C(=O)N(C)C InChI=1S/C14H16N6O6S/c1-20(2)12(22)8-5-4-6-15-11(8)27(24,25)19-14(23)18-13-16-9(21)7-10(17-13)26-3/h4-7H,1-3H3,(H3,16,17,18,19,21,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Nicosulfuron (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance 2-{[(4-Hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,Ndimethylpyridine-3-carboxamide 2-{[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,N-dimethylpyridine-3-carboxamide Not in list C14H16N6O6S O=S(=O)(NC(=O)Nc1nc(O)cc(OC)n1)c2ncccc2C(=O)N(C)C InChI=1S/C14H16N6O6S/c1-20(2)12(22)8-5-4-6-15-11(8)27(24,25)19-14(23)18-13-16-9(21)7-10(17-13)26-3/h4-7H,1-3H3,(H3,16,17,18,19,21,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Nicosulfuron (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance 2-{[(4-Hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,Ndimethylpyridine-3-carboxamide 2-{[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,N-dimethylpyridine-3-carboxamide Not in list C14H16N6O6S O=S(=O)(NC(=O)Nc1nc(O)cc(OC)n1)c2ncccc2C(=O)N(C)C InChI=1S/C14H16N6O6S/c1-20(2)12(22)8-5-4-6-15-11(8)27(24,25)19-14(23)18-13-16-9(21)7-10(17-13)26-3/h4-7H,1-3H3,(H3,16,17,18,19,21,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Nicosulfuron (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance 2-{[(4-Hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,Ndimethylpyridine-3-carboxamide 2-{[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,N-dimethylpyridine-3-carboxamide Not in list C14H16N6O6S O=S(=O)(NC(=O)Nc1nc(O)cc(OC)n1)c2ncccc2C(=O)N(C)C InChI=1S/C14H16N6O6S/c1-20(2)12(22)8-5-4-6-15-11(8)27(24,25)19-14(23)18-13-16-9(21)7-10(17-13)26-3/h4-7H,1-3H3,(H3,16,17,18,19,21,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Nicosulfuron (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance 2-{[(4-Hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,Ndimethylpyridine-3-carboxamide 2-{[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,N-dimethylpyridine-3-carboxamide Not in list C14H16N6O6S O=S(=O)(NC(=O)Nc1nc(O)cc(OC)n1)c2ncccc2C(=O)N(C)C InChI=1S/C14H16N6O6S/c1-20(2)12(22)8-5-4-6-15-11(8)27(24,25)19-14(23)18-13-16-9(21)7-10(17-13)26-3/h4-7H,1-3H3,(H3,16,17,18,19,21,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Nicosulfuron (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance 2-{[(4-Hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,Ndimethylpyridine-3-carboxamide 2-{[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,N-dimethylpyridine-3-carboxamide Not in list C14H16N6O6S O=S(=O)(NC(=O)Nc1nc(O)cc(OC)n1)c2ncccc2C(=O)N(C)C InChI=1S/C14H16N6O6S/c1-20(2)12(22)8-5-4-6-15-11(8)27(24,25)19-14(23)18-13-16-9(21)7-10(17-13)26-3/h4-7H,1-3H3,(H3,16,17,18,19,21,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Nicosulfuron (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance 2-{[(4-Hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,Ndimethylpyridine-3-carboxamide 2-{[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,N-dimethylpyridine-3-carboxamide Not in list C14H16N6O6S O=S(=O)(NC(=O)Nc1nc(O)cc(OC)n1)c2ncccc2C(=O)N(C)C InChI=1S/C14H16N6O6S/c1-20(2)12(22)8-5-4-6-15-11(8)27(24,25)19-14(23)18-13-16-9(21)7-10(17-13)26-3/h4-7H,1-3H3,(H3,16,17,18,19,21,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Nicosulfuron (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance 2-{[(4-Hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,Ndimethylpyridine-3-carboxamide 2-{[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,N-dimethylpyridine-3-carboxamide Not in list C14H16N6O6S O=S(=O)(NC(=O)Nc1nc(O)cc(OC)n1)c2ncccc2C(=O)N(C)C InChI=1S/C14H16N6O6S/c1-20(2)12(22)8-5-4-6-15-11(8)27(24,25)19-14(23)18-13-16-9(21)7-10(17-13)26-3/h4-7H,1-3H3,(H3,16,17,18,19,21,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Nicosulfuron (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance 2-{[(4-Hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,Ndimethylpyridine-3-carboxamide 2-{[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,N-dimethylpyridine-3-carboxamide Not in list C14H16N6O6S O=S(=O)(NC(=O)Nc1nc(O)cc(OC)n1)c2ncccc2C(=O)N(C)C InChI=1S/C14H16N6O6S/c1-20(2)12(22)8-5-4-6-15-11(8)27(24,25)19-14(23)18-13-16-9(21)7-10(17-13)26-3/h4-7H,1-3H3,(H3,16,17,18,19,21,23) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative large colonies RMS: The United Kingdom Nicosulfuron (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance 2-{[(4-Hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,Ndimethylpyridine-3-carboxamide 2-{[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,N-dimethylpyridine-3-carboxamide Not in list C14H16N6O6S O=S(=O)(NC(=O)Nc1nc(O)cc(OC)n1)c2ncccc2C(=O)N(C)C InChI=1S/C14H16N6O6S/c1-20(2)12(22)8-5-4-6-15-11(8)27(24,25)19-14(23)18-13-16-9(21)7-10(17-13)26-3/h4-7H,1-3H3,(H3,16,17,18,19,21,23) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative small colonies RMS: The United Kingdom Nicosulfuron (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance 2-{[(4-Hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,Ndimethylpyridine-3-carboxamide 2-{[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,N-dimethylpyridine-3-carboxamide Not in list C14H16N6O6S O=S(=O)(NC(=O)Nc1nc(O)cc(OC)n1)c2ncccc2C(=O)N(C)C InChI=1S/C14H16N6O6S/c1-20(2)12(22)8-5-4-6-15-11(8)27(24,25)19-14(23)18-13-16-9(21)7-10(17-13)26-3/h4-7H,1-3H3,(H3,16,17,18,19,21,23) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative small colonies RMS: The United Kingdom Nicosulfuron (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance 2-{[(4-Hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,Ndimethylpyridine-3-carboxamide 2-{[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,N-dimethylpyridine-3-carboxamide Not in list C14H16N6O6S O=S(=O)(NC(=O)Nc1nc(O)cc(OC)n1)c2ncccc2C(=O)N(C)C InChI=1S/C14H16N6O6S/c1-20(2)12(22)8-5-4-6-15-11(8)27(24,25)19-14(23)18-13-16-9(21)7-10(17-13)26-3/h4-7H,1-3H3,(H3,16,17,18,19,21,23) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative large colonies RMS: The United Kingdom Nicosulfuron (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance 2-{[(4-Hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,Ndimethylpyridine-3-carboxamide 2-{[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,N-dimethylpyridine-3-carboxamide Not in list C14H16N6O6S O=S(=O)(NC(=O)Nc1nc(O)cc(OC)n1)c2ncccc2C(=O)N(C)C InChI=1S/C14H16N6O6S/c1-20(2)12(22)8-5-4-6-15-11(8)27(24,25)19-14(23)18-13-16-9(21)7-10(17-13)26-3/h4-7H,1-3H3,(H3,16,17,18,19,21,23) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Nicosulfuron (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Nicosulfuron 111991-09-4 single chemical entity Component is a metabolite of the substance 2-{[(4-Hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,Ndimethylpyridine-3-carboxamide 2-{[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,N-dimethylpyridine-3-carboxamide Not in list C14H16N6O6S O=S(=O)(NC(=O)Nc1nc(O)cc(OC)n1)c2ncccc2C(=O)N(C)C InChI=1S/C14H16N6O6S/c1-20(2)12(22)8-5-4-6-15-11(8)27(24,25)19-14(23)18-13-16-9(21)7-10(17-13)26-3/h4-7H,1-3H3,(H3,16,17,18,19,21,23) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Nicosulfuron (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron 29Jan2008 2008 doi:10.2903/j.efsa.2008.120r
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is identical to the substance Metalaxyl-M 615-135-6 70630-17-0 methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate Metalaxyl-M C15H21NO4 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is identical to the substance Metalaxyl-M 615-135-6 70630-17-0 methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate Metalaxyl-M C15H21NO4 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is identical to the substance Metalaxyl-M 615-135-6 70630-17-0 methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate Metalaxyl-M C15H21NO4 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is identical to the substance Metalaxyl-M 615-135-6 70630-17-0 methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate Metalaxyl-M C15H21NO4 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is identical to the substance Metalaxyl-M 615-135-6 70630-17-0 methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate Metalaxyl-M C15H21NO4 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is identical to the substance Metalaxyl-M 615-135-6 70630-17-0 methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate Metalaxyl-M C15H21NO4 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is identical to the substance Metalaxyl-M 615-135-6 70630-17-0 methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate Metalaxyl-M C15H21NO4 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is identical to the substance Metalaxyl-M 615-135-6 70630-17-0 methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate Metalaxyl-M C15H21NO4 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is identical to the substance Metalaxyl-M 615-135-6 70630-17-0 methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate Metalaxyl-M C15H21NO4 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is identical to the substance Metalaxyl-M 615-135-6 70630-17-0 methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate Metalaxyl-M C15H21NO4 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is identical to the substance Metalaxyl-M 615-135-6 70630-17-0 methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate Metalaxyl-M C15H21NO4 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is identical to the substance Metalaxyl-M 615-135-6 70630-17-0 methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate Metalaxyl-M C15H21NO4 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is identical to the substance Metalaxyl-M 615-135-6 70630-17-0 methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate Metalaxyl-M C15H21NO4 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Ambiguous RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is identical to the substance Metalaxyl-M 615-135-6 70630-17-0 methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate Metalaxyl-M C15H21NO4 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is identical to the substance Metalaxyl-M 615-135-6 70630-17-0 methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate Metalaxyl-M C15H21NO4 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is identical to the substance Metalaxyl-M 615-135-6 70630-17-0 methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate Metalaxyl-M C15H21NO4 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is identical to the substance Metalaxyl-M 615-135-6 70630-17-0 methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate Metalaxyl-M C15H21NO4 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2-[((RS)-1-Carboxy-ethyl)-(2-methoxy-acetyl)-amino]-3-methyl-benzoic acid 2-[(1-carboxyethyl)(methoxyacetyl)amino]-3-methylbenzoic acid Not in list C14H17NO6 CC(N(C(=O)COC)c1c(C)cccc1C(=O)O)C(=O)O InChI=1S/C14H17NO6/c1-8-5-4-6-10(14(19)20)12(8)15(9(2)13(17)18)11(16)7-21-3/h4-6,9H,7H2,1-3H3,(H,17,18)(H,19,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2-[((RS)-1-Carboxy-ethyl)-(2-methoxy-acetyl)-amino]-3-methyl-benzoic acid 2-[(1-carboxyethyl)(methoxyacetyl)amino]-3-methylbenzoic acid Not in list C14H17NO6 CC(N(C(=O)COC)c1c(C)cccc1C(=O)O)C(=O)O InChI=1S/C14H17NO6/c1-8-5-4-6-10(14(19)20)12(8)15(9(2)13(17)18)11(16)7-21-3/h4-6,9H,7H2,1-3H3,(H,17,18)(H,19,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2-[((RS)-1-Carboxy-ethyl)-(2-methoxy-acetyl)-amino]-3-methyl-benzoic acid 2-[(1-carboxyethyl)(methoxyacetyl)amino]-3-methylbenzoic acid Not in list C14H17NO6 CC(N(C(=O)COC)c1c(C)cccc1C(=O)O)C(=O)O InChI=1S/C14H17NO6/c1-8-5-4-6-10(14(19)20)12(8)15(9(2)13(17)18)11(16)7-21-3/h4-6,9H,7H2,1-3H3,(H,17,18)(H,19,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2-[((RS)-1-Carboxy-ethyl)-(2-methoxy-acetyl)-amino]-3-methyl-benzoic acid 2-[(1-carboxyethyl)(methoxyacetyl)amino]-3-methylbenzoic acid Not in list C14H17NO6 CC(N(C(=O)COC)c1c(C)cccc1C(=O)O)C(=O)O InChI=1S/C14H17NO6/c1-8-5-4-6-10(14(19)20)12(8)15(9(2)13(17)18)11(16)7-21-3/h4-6,9H,7H2,1-3H3,(H,17,18)(H,19,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2-[((RS)-1-Carboxy-ethyl)-(2-methoxy-acetyl)-amino]-3-methyl-benzoic acid 2-[(1-carboxyethyl)(methoxyacetyl)amino]-3-methylbenzoic acid Not in list C14H17NO6 CC(N(C(=O)COC)c1c(C)cccc1C(=O)O)C(=O)O InChI=1S/C14H17NO6/c1-8-5-4-6-10(14(19)20)12(8)15(9(2)13(17)18)11(16)7-21-3/h4-6,9H,7H2,1-3H3,(H,17,18)(H,19,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2-[((RS)-1-Carboxy-ethyl)-(2-methoxy-acetyl)-amino]-3-methyl-benzoic acid 2-[(1-carboxyethyl)(methoxyacetyl)amino]-3-methylbenzoic acid Not in list C14H17NO6 CC(N(C(=O)COC)c1c(C)cccc1C(=O)O)C(=O)O InChI=1S/C14H17NO6/c1-8-5-4-6-10(14(19)20)12(8)15(9(2)13(17)18)11(16)7-21-3/h4-6,9H,7H2,1-3H3,(H,17,18)(H,19,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2-[((RS)-1-Carboxy-ethyl)-(2-methoxy-acetyl)-amino]-3-methyl-benzoic acid 2-[(1-carboxyethyl)(methoxyacetyl)amino]-3-methylbenzoic acid Not in list C14H17NO6 CC(N(C(=O)COC)c1c(C)cccc1C(=O)O)C(=O)O InChI=1S/C14H17NO6/c1-8-5-4-6-10(14(19)20)12(8)15(9(2)13(17)18)11(16)7-21-3/h4-6,9H,7H2,1-3H3,(H,17,18)(H,19,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2-[((RS)-1-Carboxy-ethyl)-(2-methoxy-acetyl)-amino]-3-methyl-benzoic acid 2-[(1-carboxyethyl)(methoxyacetyl)amino]-3-methylbenzoic acid Not in list C14H17NO6 CC(N(C(=O)COC)c1c(C)cccc1C(=O)O)C(=O)O InChI=1S/C14H17NO6/c1-8-5-4-6-10(14(19)20)12(8)15(9(2)13(17)18)11(16)7-21-3/h4-6,9H,7H2,1-3H3,(H,17,18)(H,19,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2-[((RS)-1-Carboxy-ethyl)-(2-methoxy-acetyl)-amino]-3-methyl-benzoic acid 2-[(1-carboxyethyl)(methoxyacetyl)amino]-3-methylbenzoic acid Not in list C14H17NO6 CC(N(C(=O)COC)c1c(C)cccc1C(=O)O)C(=O)O InChI=1S/C14H17NO6/c1-8-5-4-6-10(14(19)20)12(8)15(9(2)13(17)18)11(16)7-21-3/h4-6,9H,7H2,1-3H3,(H,17,18)(H,19,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2-[((RS)-1-Carboxy-ethyl)-(2-methoxy-acetyl)-amino]-3-methyl-benzoic acid 2-[(1-carboxyethyl)(methoxyacetyl)amino]-3-methylbenzoic acid Not in list C14H17NO6 CC(N(C(=O)COC)c1c(C)cccc1C(=O)O)C(=O)O InChI=1S/C14H17NO6/c1-8-5-4-6-10(14(19)20)12(8)15(9(2)13(17)18)11(16)7-21-3/h4-6,9H,7H2,1-3H3,(H,17,18)(H,19,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2-[((RS)-1-Carboxy-ethyl)-(2-methoxy-acetyl)-amino]-3-methyl-benzoic acid 2-[(1-carboxyethyl)(methoxyacetyl)amino]-3-methylbenzoic acid Not in list C14H17NO6 CC(N(C(=O)COC)c1c(C)cccc1C(=O)O)C(=O)O InChI=1S/C14H17NO6/c1-8-5-4-6-10(14(19)20)12(8)15(9(2)13(17)18)11(16)7-21-3/h4-6,9H,7H2,1-3H3,(H,17,18)(H,19,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2-[((RS)-1-Carboxy-ethyl)-(2-methoxy-acetyl)-amino]-3-methyl-benzoic acid 2-[(1-carboxyethyl)(methoxyacetyl)amino]-3-methylbenzoic acid Not in list C14H17NO6 CC(N(C(=O)COC)c1c(C)cccc1C(=O)O)C(=O)O InChI=1S/C14H17NO6/c1-8-5-4-6-10(14(19)20)12(8)15(9(2)13(17)18)11(16)7-21-3/h4-6,9H,7H2,1-3H3,(H,17,18)(H,19,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2-[((RS)-1-Carboxy-ethyl)-(2-methoxy-acetyl)-amino]-3-methyl-benzoic acid 2-[(1-carboxyethyl)(methoxyacetyl)amino]-3-methylbenzoic acid Not in list C14H17NO6 CC(N(C(=O)COC)c1c(C)cccc1C(=O)O)C(=O)O InChI=1S/C14H17NO6/c1-8-5-4-6-10(14(19)20)12(8)15(9(2)13(17)18)11(16)7-21-3/h4-6,9H,7H2,1-3H3,(H,17,18)(H,19,20) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2-[((RS)-1-Carboxy-ethyl)-(2-methoxy-acetyl)-amino]-3-methyl-benzoic acid 2-[(1-carboxyethyl)(methoxyacetyl)amino]-3-methylbenzoic acid Not in list C14H17NO6 CC(N(C(=O)COC)c1c(C)cccc1C(=O)O)C(=O)O InChI=1S/C14H17NO6/c1-8-5-4-6-10(14(19)20)12(8)15(9(2)13(17)18)11(16)7-21-3/h4-6,9H,7H2,1-3H3,(H,17,18)(H,19,20) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2-[((RS)-1-Carboxy-ethyl)-(2-methoxy-acetyl)-amino]-3-methyl-benzoic acid 2-[(1-carboxyethyl)(methoxyacetyl)amino]-3-methylbenzoic acid Not in list C14H17NO6 CC(N(C(=O)COC)c1c(C)cccc1C(=O)O)C(=O)O InChI=1S/C14H17NO6/c1-8-5-4-6-10(14(19)20)12(8)15(9(2)13(17)18)11(16)7-21-3/h4-6,9H,7H2,1-3H3,(H,17,18)(H,19,20) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative large colonies RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2-[((RS)-1-Carboxy-ethyl)-(2-methoxy-acetyl)-amino]-3-methyl-benzoic acid 2-[(1-carboxyethyl)(methoxyacetyl)amino]-3-methylbenzoic acid Not in list C14H17NO6 CC(N(C(=O)COC)c1c(C)cccc1C(=O)O)C(=O)O InChI=1S/C14H17NO6/c1-8-5-4-6-10(14(19)20)12(8)15(9(2)13(17)18)11(16)7-21-3/h4-6,9H,7H2,1-3H3,(H,17,18)(H,19,20) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative large colonies RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2-[((RS)-1-Carboxy-ethyl)-(2-methoxy-acetyl)-amino]-3-methyl-benzoic acid 2-[(1-carboxyethyl)(methoxyacetyl)amino]-3-methylbenzoic acid Not in list C14H17NO6 CC(N(C(=O)COC)c1c(C)cccc1C(=O)O)C(=O)O InChI=1S/C14H17NO6/c1-8-5-4-6-10(14(19)20)12(8)15(9(2)13(17)18)11(16)7-21-3/h4-6,9H,7H2,1-3H3,(H,17,18)(H,19,20) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative small colonies RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2-[((RS)-1-Carboxy-ethyl)-(2-methoxy-acetyl)-amino]-3-methyl-benzoic acid 2-[(1-carboxyethyl)(methoxyacetyl)amino]-3-methylbenzoic acid Not in list C14H17NO6 CC(N(C(=O)COC)c1c(C)cccc1C(=O)O)C(=O)O InChI=1S/C14H17NO6/c1-8-5-4-6-10(14(19)20)12(8)15(9(2)13(17)18)11(16)7-21-3/h4-6,9H,7H2,1-3H3,(H,17,18)(H,19,20) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative small colonies RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2-[((RS)-1-Carboxy-ethyl)-(2-methoxy-acetyl)-amino]-3-methyl-benzoic acid 2-[(1-carboxyethyl)(methoxyacetyl)amino]-3-methylbenzoic acid Not in list C14H17NO6 CC(N(C(=O)COC)c1c(C)cccc1C(=O)O)C(=O)O InChI=1S/C14H17NO6/c1-8-5-4-6-10(14(19)20)12(8)15(9(2)13(17)18)11(16)7-21-3/h4-6,9H,7H2,1-3H3,(H,17,18)(H,19,20) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2-[((RS)-1-Carboxy-ethyl)-(2-methoxy-acetyl)-amino]-3-methyl-benzoic acid 2-[(1-carboxyethyl)(methoxyacetyl)amino]-3-methylbenzoic acid Not in list C14H17NO6 CC(N(C(=O)COC)c1c(C)cccc1C(=O)O)C(=O)O InChI=1S/C14H17NO6/c1-8-5-4-6-10(14(19)20)12(8)15(9(2)13(17)18)11(16)7-21-3/h4-6,9H,7H2,1-3H3,(H,17,18)(H,19,20) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance (RS)-2-[(2,6-Dimethyl-phenyl)-(2-methoxy-acetyl)-amino]-propionic acid 2-[(2,6-dimethylphenyl)(methoxyacetyl)amino]propanoic acid Not in list C14H19NO4 CC(N(C(=O)COC)c1c(C)cccc1C)C(=O)O InChI=1S/C14H19NO4/c1-9-6-5-7-10(2)13(9)15(11(3)14(17)18)12(16)8-19-4/h5-7,11H,8H2,1-4H3,(H,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance (RS)-2-[(2,6-Dimethyl-phenyl)-(2-methoxy-acetyl)-amino]-propionic acid 2-[(2,6-dimethylphenyl)(methoxyacetyl)amino]propanoic acid Not in list C14H19NO4 CC(N(C(=O)COC)c1c(C)cccc1C)C(=O)O InChI=1S/C14H19NO4/c1-9-6-5-7-10(2)13(9)15(11(3)14(17)18)12(16)8-19-4/h5-7,11H,8H2,1-4H3,(H,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance (RS)-2-[(2,6-Dimethyl-phenyl)-(2-methoxy-acetyl)-amino]-propionic acid 2-[(2,6-dimethylphenyl)(methoxyacetyl)amino]propanoic acid Not in list C14H19NO4 CC(N(C(=O)COC)c1c(C)cccc1C)C(=O)O InChI=1S/C14H19NO4/c1-9-6-5-7-10(2)13(9)15(11(3)14(17)18)12(16)8-19-4/h5-7,11H,8H2,1-4H3,(H,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance (RS)-2-[(2,6-Dimethyl-phenyl)-(2-methoxy-acetyl)-amino]-propionic acid 2-[(2,6-dimethylphenyl)(methoxyacetyl)amino]propanoic acid Not in list C14H19NO4 CC(N(C(=O)COC)c1c(C)cccc1C)C(=O)O InChI=1S/C14H19NO4/c1-9-6-5-7-10(2)13(9)15(11(3)14(17)18)12(16)8-19-4/h5-7,11H,8H2,1-4H3,(H,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance (RS)-2-[(2,6-Dimethyl-phenyl)-(2-methoxy-acetyl)-amino]-propionic acid 2-[(2,6-dimethylphenyl)(methoxyacetyl)amino]propanoic acid Not in list C14H19NO4 CC(N(C(=O)COC)c1c(C)cccc1C)C(=O)O InChI=1S/C14H19NO4/c1-9-6-5-7-10(2)13(9)15(11(3)14(17)18)12(16)8-19-4/h5-7,11H,8H2,1-4H3,(H,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance (RS)-2-[(2,6-Dimethyl-phenyl)-(2-methoxy-acetyl)-amino]-propionic acid 2-[(2,6-dimethylphenyl)(methoxyacetyl)amino]propanoic acid Not in list C14H19NO4 CC(N(C(=O)COC)c1c(C)cccc1C)C(=O)O InChI=1S/C14H19NO4/c1-9-6-5-7-10(2)13(9)15(11(3)14(17)18)12(16)8-19-4/h5-7,11H,8H2,1-4H3,(H,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance (RS)-2-[(2,6-Dimethyl-phenyl)-(2-methoxy-acetyl)-amino]-propionic acid 2-[(2,6-dimethylphenyl)(methoxyacetyl)amino]propanoic acid Not in list C14H19NO4 CC(N(C(=O)COC)c1c(C)cccc1C)C(=O)O InChI=1S/C14H19NO4/c1-9-6-5-7-10(2)13(9)15(11(3)14(17)18)12(16)8-19-4/h5-7,11H,8H2,1-4H3,(H,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance (RS)-2-[(2,6-Dimethyl-phenyl)-(2-methoxy-acetyl)-amino]-propionic acid 2-[(2,6-dimethylphenyl)(methoxyacetyl)amino]propanoic acid Not in list C14H19NO4 CC(N(C(=O)COC)c1c(C)cccc1C)C(=O)O InChI=1S/C14H19NO4/c1-9-6-5-7-10(2)13(9)15(11(3)14(17)18)12(16)8-19-4/h5-7,11H,8H2,1-4H3,(H,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance (RS)-2-[(2,6-Dimethyl-phenyl)-(2-methoxy-acetyl)-amino]-propionic acid 2-[(2,6-dimethylphenyl)(methoxyacetyl)amino]propanoic acid Not in list C14H19NO4 CC(N(C(=O)COC)c1c(C)cccc1C)C(=O)O InChI=1S/C14H19NO4/c1-9-6-5-7-10(2)13(9)15(11(3)14(17)18)12(16)8-19-4/h5-7,11H,8H2,1-4H3,(H,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance (RS)-2-[(2,6-Dimethyl-phenyl)-(2-methoxy-acetyl)-amino]-propionic acid 2-[(2,6-dimethylphenyl)(methoxyacetyl)amino]propanoic acid Not in list C14H19NO4 CC(N(C(=O)COC)c1c(C)cccc1C)C(=O)O InChI=1S/C14H19NO4/c1-9-6-5-7-10(2)13(9)15(11(3)14(17)18)12(16)8-19-4/h5-7,11H,8H2,1-4H3,(H,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance (RS)-2-[(2,6-Dimethyl-phenyl)-(2-methoxy-acetyl)-amino]-propionic acid 2-[(2,6-dimethylphenyl)(methoxyacetyl)amino]propanoic acid Not in list C14H19NO4 CC(N(C(=O)COC)c1c(C)cccc1C)C(=O)O InChI=1S/C14H19NO4/c1-9-6-5-7-10(2)13(9)15(11(3)14(17)18)12(16)8-19-4/h5-7,11H,8H2,1-4H3,(H,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance (RS)-2-[(2,6-Dimethyl-phenyl)-(2-methoxy-acetyl)-amino]-propionic acid 2-[(2,6-dimethylphenyl)(methoxyacetyl)amino]propanoic acid Not in list C14H19NO4 CC(N(C(=O)COC)c1c(C)cccc1C)C(=O)O InChI=1S/C14H19NO4/c1-9-6-5-7-10(2)13(9)15(11(3)14(17)18)12(16)8-19-4/h5-7,11H,8H2,1-4H3,(H,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance (RS)-2-[(2,6-Dimethyl-phenyl)-(2-methoxy-acetyl)-amino]-propionic acid 2-[(2,6-dimethylphenyl)(methoxyacetyl)amino]propanoic acid Not in list C14H19NO4 CC(N(C(=O)COC)c1c(C)cccc1C)C(=O)O InChI=1S/C14H19NO4/c1-9-6-5-7-10(2)13(9)15(11(3)14(17)18)12(16)8-19-4/h5-7,11H,8H2,1-4H3,(H,17,18) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance (RS)-2-[(2,6-Dimethyl-phenyl)-(2-methoxy-acetyl)-amino]-propionic acid 2-[(2,6-dimethylphenyl)(methoxyacetyl)amino]propanoic acid Not in list C14H19NO4 CC(N(C(=O)COC)c1c(C)cccc1C)C(=O)O InChI=1S/C14H19NO4/c1-9-6-5-7-10(2)13(9)15(11(3)14(17)18)12(16)8-19-4/h5-7,11H,8H2,1-4H3,(H,17,18) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance (RS)-2-[(2,6-Dimethyl-phenyl)-(2-methoxy-acetyl)-amino]-propionic acid 2-[(2,6-dimethylphenyl)(methoxyacetyl)amino]propanoic acid Not in list C14H19NO4 CC(N(C(=O)COC)c1c(C)cccc1C)C(=O)O InChI=1S/C14H19NO4/c1-9-6-5-7-10(2)13(9)15(11(3)14(17)18)12(16)8-19-4/h5-7,11H,8H2,1-4H3,(H,17,18) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative small colonies RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance (RS)-2-[(2,6-Dimethyl-phenyl)-(2-methoxy-acetyl)-amino]-propionic acid 2-[(2,6-dimethylphenyl)(methoxyacetyl)amino]propanoic acid Not in list C14H19NO4 CC(N(C(=O)COC)c1c(C)cccc1C)C(=O)O InChI=1S/C14H19NO4/c1-9-6-5-7-10(2)13(9)15(11(3)14(17)18)12(16)8-19-4/h5-7,11H,8H2,1-4H3,(H,17,18) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative large colonies RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance (RS)-2-[(2,6-Dimethyl-phenyl)-(2-methoxy-acetyl)-amino]-propionic acid 2-[(2,6-dimethylphenyl)(methoxyacetyl)amino]propanoic acid Not in list C14H19NO4 CC(N(C(=O)COC)c1c(C)cccc1C)C(=O)O InChI=1S/C14H19NO4/c1-9-6-5-7-10(2)13(9)15(11(3)14(17)18)12(16)8-19-4/h5-7,11H,8H2,1-4H3,(H,17,18) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative large colonies RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance (RS)-2-[(2,6-Dimethyl-phenyl)-(2-methoxy-acetyl)-amino]-propionic acid 2-[(2,6-dimethylphenyl)(methoxyacetyl)amino]propanoic acid Not in list C14H19NO4 CC(N(C(=O)COC)c1c(C)cccc1C)C(=O)O InChI=1S/C14H19NO4/c1-9-6-5-7-10(2)13(9)15(11(3)14(17)18)12(16)8-19-4/h5-7,11H,8H2,1-4H3,(H,17,18) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative small colonies RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance N-(2,6-Dimethyl-phenyl)-2-methoxy-acetamide N-(2,6-dimethylphenyl)-2-methoxyacetamide Not in list C11H15NO2 O=C(Nc1c(C)cccc1C)COC InChI=1S/C11H15NO2/c1-8-5-4-6-9(2)11(8)12-10(13)7-14-3/h4-6H,7H2,1-3H3,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance N-(2,6-Dimethyl-phenyl)-2-methoxy-acetamide N-(2,6-dimethylphenyl)-2-methoxyacetamide Not in list C11H15NO2 O=C(Nc1c(C)cccc1C)COC InChI=1S/C11H15NO2/c1-8-5-4-6-9(2)11(8)12-10(13)7-14-3/h4-6H,7H2,1-3H3,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance N-(2,6-Dimethyl-phenyl)-2-methoxy-acetamide N-(2,6-dimethylphenyl)-2-methoxyacetamide Not in list C11H15NO2 O=C(Nc1c(C)cccc1C)COC InChI=1S/C11H15NO2/c1-8-5-4-6-9(2)11(8)12-10(13)7-14-3/h4-6H,7H2,1-3H3,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance N-(2,6-Dimethyl-phenyl)-2-methoxy-acetamide N-(2,6-dimethylphenyl)-2-methoxyacetamide Not in list C11H15NO2 O=C(Nc1c(C)cccc1C)COC InChI=1S/C11H15NO2/c1-8-5-4-6-9(2)11(8)12-10(13)7-14-3/h4-6H,7H2,1-3H3,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance N-(2,6-Dimethyl-phenyl)-2-methoxy-acetamide N-(2,6-dimethylphenyl)-2-methoxyacetamide Not in list C11H15NO2 O=C(Nc1c(C)cccc1C)COC InChI=1S/C11H15NO2/c1-8-5-4-6-9(2)11(8)12-10(13)7-14-3/h4-6H,7H2,1-3H3,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance N-(2,6-Dimethyl-phenyl)-2-methoxy-acetamide N-(2,6-dimethylphenyl)-2-methoxyacetamide Not in list C11H15NO2 O=C(Nc1c(C)cccc1C)COC InChI=1S/C11H15NO2/c1-8-5-4-6-9(2)11(8)12-10(13)7-14-3/h4-6H,7H2,1-3H3,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance N-(2,6-Dimethyl-phenyl)-2-methoxy-acetamide N-(2,6-dimethylphenyl)-2-methoxyacetamide Not in list C11H15NO2 O=C(Nc1c(C)cccc1C)COC InChI=1S/C11H15NO2/c1-8-5-4-6-9(2)11(8)12-10(13)7-14-3/h4-6H,7H2,1-3H3,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance N-(2,6-Dimethyl-phenyl)-2-methoxy-acetamide N-(2,6-dimethylphenyl)-2-methoxyacetamide Not in list C11H15NO2 O=C(Nc1c(C)cccc1C)COC InChI=1S/C11H15NO2/c1-8-5-4-6-9(2)11(8)12-10(13)7-14-3/h4-6H,7H2,1-3H3,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance N-(2,6-Dimethyl-phenyl)-2-methoxy-acetamide N-(2,6-dimethylphenyl)-2-methoxyacetamide Not in list C11H15NO2 O=C(Nc1c(C)cccc1C)COC InChI=1S/C11H15NO2/c1-8-5-4-6-9(2)11(8)12-10(13)7-14-3/h4-6H,7H2,1-3H3,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance N-(2,6-Dimethyl-phenyl)-2-methoxy-acetamide N-(2,6-dimethylphenyl)-2-methoxyacetamide Not in list C11H15NO2 O=C(Nc1c(C)cccc1C)COC InChI=1S/C11H15NO2/c1-8-5-4-6-9(2)11(8)12-10(13)7-14-3/h4-6H,7H2,1-3H3,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance N-(2,6-Dimethyl-phenyl)-2-methoxy-acetamide N-(2,6-dimethylphenyl)-2-methoxyacetamide Not in list C11H15NO2 O=C(Nc1c(C)cccc1C)COC InChI=1S/C11H15NO2/c1-8-5-4-6-9(2)11(8)12-10(13)7-14-3/h4-6H,7H2,1-3H3,(H,12,13) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative large colonies RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance N-(2,6-Dimethyl-phenyl)-2-methoxy-acetamide N-(2,6-dimethylphenyl)-2-methoxyacetamide Not in list C11H15NO2 O=C(Nc1c(C)cccc1C)COC InChI=1S/C11H15NO2/c1-8-5-4-6-9(2)11(8)12-10(13)7-14-3/h4-6H,7H2,1-3H3,(H,12,13) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Negative large colonies RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance N-(2,6-Dimethyl-phenyl)-2-methoxy-acetamide N-(2,6-dimethylphenyl)-2-methoxyacetamide Not in list C11H15NO2 O=C(Nc1c(C)cccc1C)COC InChI=1S/C11H15NO2/c1-8-5-4-6-9(2)11(8)12-10(13)7-14-3/h4-6H,7H2,1-3H3,(H,12,13) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative small colonies RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance N-(2,6-Dimethyl-phenyl)-2-methoxy-acetamide N-(2,6-dimethylphenyl)-2-methoxyacetamide Not in list C11H15NO2 O=C(Nc1c(C)cccc1C)COC InChI=1S/C11H15NO2/c1-8-5-4-6-9(2)11(8)12-10(13)7-14-3/h4-6H,7H2,1-3H3,(H,12,13) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Negative small colonies RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance N-(2,6-Dimethyl-phenyl)-2-methoxy-acetamide N-(2,6-dimethylphenyl)-2-methoxyacetamide Not in list C11H15NO2 O=C(Nc1c(C)cccc1C)COC InChI=1S/C11H15NO2/c1-8-5-4-6-9(2)11(8)12-10(13)7-14-3/h4-6H,7H2,1-3H3,(H,12,13) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance N-(2,6-Dimethyl-phenyl)-2-methoxy-acetamide N-(2,6-dimethylphenyl)-2-methoxyacetamide Not in list C11H15NO2 O=C(Nc1c(C)cccc1C)COC InChI=1S/C11H15NO2/c1-8-5-4-6-9(2)11(8)12-10(13)7-14-3/h4-6H,7H2,1-3H3,(H,12,13) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is identical to the substance Terbuthylazine 227-637-9 5915-41-3 N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine Terbuthylazine C9H16ClN5 CCNc1nc(Cl)nc(NC(C)(C)C)n1 InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is identical to the substance Terbuthylazine 227-637-9 5915-41-3 N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine Terbuthylazine C9H16ClN5 CCNc1nc(Cl)nc(NC(C)(C)C)n1 InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is identical to the substance Terbuthylazine 227-637-9 5915-41-3 N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine Terbuthylazine C9H16ClN5 CCNc1nc(Cl)nc(NC(C)(C)C)n1 InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is identical to the substance Terbuthylazine 227-637-9 5915-41-3 N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine Terbuthylazine C9H16ClN5 CCNc1nc(Cl)nc(NC(C)(C)C)n1 InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is identical to the substance Terbuthylazine 227-637-9 5915-41-3 N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine Terbuthylazine C9H16ClN5 CCNc1nc(Cl)nc(NC(C)(C)C)n1 InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is identical to the substance Terbuthylazine 227-637-9 5915-41-3 N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine Terbuthylazine C9H16ClN5 CCNc1nc(Cl)nc(NC(C)(C)C)n1 InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is identical to the substance Terbuthylazine 227-637-9 5915-41-3 N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine Terbuthylazine C9H16ClN5 CCNc1nc(Cl)nc(NC(C)(C)C)n1 InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is identical to the substance Terbuthylazine 227-637-9 5915-41-3 N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine Terbuthylazine C9H16ClN5 CCNc1nc(Cl)nc(NC(C)(C)C)n1 InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is identical to the substance Terbuthylazine 227-637-9 5915-41-3 N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine Terbuthylazine C9H16ClN5 CCNc1nc(Cl)nc(NC(C)(C)C)n1 InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is identical to the substance Terbuthylazine 227-637-9 5915-41-3 N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine Terbuthylazine C9H16ClN5 CCNc1nc(Cl)nc(NC(C)(C)C)n1 InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is identical to the substance Terbuthylazine 227-637-9 5915-41-3 N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine Terbuthylazine C9H16ClN5 CCNc1nc(Cl)nc(NC(C)(C)C)n1 InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is identical to the substance Terbuthylazine 227-637-9 5915-41-3 N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine Terbuthylazine C9H16ClN5 CCNc1nc(Cl)nc(NC(C)(C)C)n1 InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is identical to the substance Terbuthylazine 227-637-9 5915-41-3 N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine Terbuthylazine C9H16ClN5 CCNc1nc(Cl)nc(NC(C)(C)C)n1 InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is identical to the substance Terbuthylazine 227-637-9 5915-41-3 N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine Terbuthylazine C9H16ClN5 CCNc1nc(Cl)nc(NC(C)(C)C)n1 InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is identical to the substance Terbuthylazine 227-637-9 5915-41-3 N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine Terbuthylazine C9H16ClN5 CCNc1nc(Cl)nc(NC(C)(C)C)n1 InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is identical to the substance Terbuthylazine 227-637-9 5915-41-3 N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine Terbuthylazine C9H16ClN5 CCNc1nc(Cl)nc(NC(C)(C)C)n1 InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is identical to the substance Terbuthylazine 227-637-9 5915-41-3 N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine Terbuthylazine C9H16ClN5 CCNc1nc(Cl)nc(NC(C)(C)C)n1 InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Tif:MAGf(SPF) 16 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is identical to the substance Terbuthylazine 227-637-9 5915-41-3 N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine Terbuthylazine C9H16ClN5 CCNc1nc(Cl)nc(NC(C)(C)C)n1 InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Tif:MAGf(SPF) 16 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is identical to the substance Terbuthylazine 227-637-9 5915-41-3 N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine Terbuthylazine C9H16ClN5 CCNc1nc(Cl)nc(NC(C)(C)C)n1 InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Tif:MAGf(SPF) 16 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is identical to the substance Terbuthylazine 227-637-9 5915-41-3 N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine Terbuthylazine C9H16ClN5 CCNc1nc(Cl)nc(NC(C)(C)C)n1 InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Tif:MAGf(SPF) 16 Male/Female oral: gavage 16.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Imazalil 252-615-0 35554-44-0 single chemical entity Component is identical to the substance Imazalil 252-615-0 35554-44-0 1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole Imazalil C14H14Cl2N2O C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: The Netherlands - CoRMS: Spain Imazalil 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil 19Mar2010 2010 doi:10.2903/j.efsa.2010.1526
+Imazalil 252-615-0 35554-44-0 single chemical entity Component is identical to the substance Imazalil 252-615-0 35554-44-0 1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole Imazalil C14H14Cl2N2O C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: The Netherlands - CoRMS: Spain Imazalil 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil 19Mar2010 2010 doi:10.2903/j.efsa.2010.1526
+Imazalil 252-615-0 35554-44-0 single chemical entity Component is identical to the substance Imazalil 252-615-0 35554-44-0 1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole Imazalil C14H14Cl2N2O C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The Netherlands - CoRMS: Spain Imazalil 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil 19Mar2010 2010 doi:10.2903/j.efsa.2010.1526
+Imazalil 252-615-0 35554-44-0 single chemical entity Component is identical to the substance Imazalil 252-615-0 35554-44-0 1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole Imazalil C14H14Cl2N2O C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The Netherlands - CoRMS: Spain Imazalil 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil 19Mar2010 2010 doi:10.2903/j.efsa.2010.1526
+Imazalil 252-615-0 35554-44-0 single chemical entity Component is identical to the substance Imazalil 252-615-0 35554-44-0 1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole Imazalil C14H14Cl2N2O C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The Netherlands - CoRMS: Spain Imazalil 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil 19Mar2010 2010 doi:10.2903/j.efsa.2010.1526
+Imazalil 252-615-0 35554-44-0 single chemical entity Component is identical to the substance Imazalil 252-615-0 35554-44-0 1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole Imazalil C14H14Cl2N2O C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The Netherlands - CoRMS: Spain Imazalil 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil 19Mar2010 2010 doi:10.2903/j.efsa.2010.1526
+Imazalil 252-615-0 35554-44-0 single chemical entity Component is identical to the substance Imazalil 252-615-0 35554-44-0 1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole Imazalil C14H14Cl2N2O C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The Netherlands - CoRMS: Spain Imazalil 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil 19Mar2010 2010 doi:10.2903/j.efsa.2010.1526
+Imazalil 252-615-0 35554-44-0 single chemical entity Component is identical to the substance Imazalil 252-615-0 35554-44-0 1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole Imazalil C14H14Cl2N2O C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The Netherlands - CoRMS: Spain Imazalil 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil 19Mar2010 2010 doi:10.2903/j.efsa.2010.1526
+Imazalil 252-615-0 35554-44-0 single chemical entity Component is identical to the substance Imazalil 252-615-0 35554-44-0 1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole Imazalil C14H14Cl2N2O C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The Netherlands - CoRMS: Spain Imazalil 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil 19Mar2010 2010 doi:10.2903/j.efsa.2010.1526
+Imazalil 252-615-0 35554-44-0 single chemical entity Component is identical to the substance Imazalil 252-615-0 35554-44-0 1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole Imazalil C14H14Cl2N2O C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The Netherlands - CoRMS: Spain Imazalil 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil 19Mar2010 2010 doi:10.2903/j.efsa.2010.1526
+Imazalil 252-615-0 35554-44-0 single chemical entity Component is identical to the substance Imazalil 252-615-0 35554-44-0 1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole Imazalil C14H14Cl2N2O C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable Rat (as animal) Not reported No data intraperitoneal no data not applicable Negative RMS: The Netherlands - CoRMS: Spain Imazalil 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil 19Mar2010 2010 doi:10.2903/j.efsa.2010.1526
+Imazalil 252-615-0 35554-44-0 single chemical entity Component is identical to the substance Imazalil 252-615-0 35554-44-0 1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole Imazalil C14H14Cl2N2O C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2 organic compound PubChem canonical SMILES PubChem InChI genome mutation Drosophila SLRL test in vivo Equivalent or similar to OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster) No data Acceptable Drosophila melanogaster (as animal) Not reported Male Not reported 3.0000000000 D no data not applicable Negative RMS: The Netherlands - CoRMS: Spain Imazalil 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil 19Mar2010 2010 doi:10.2903/j.efsa.2010.1526
+Imazalil 252-615-0 35554-44-0 single chemical entity Component is identical to the substance Imazalil 252-615-0 35554-44-0 1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole Imazalil C14H14Cl2N2O C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vitro No guideline available Not reported Not applicable Acceptable Human (as organism) lymphocytes Not reported yes no data Positive RMS: The Netherlands - CoRMS: Spain Imazalil 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil 19Mar2010 2010 doi:10.2903/j.efsa.2010.1526
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is identical to the substance Terbuthylazine 227-637-9 5915-41-3 N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine Terbuthylazine C9H16ClN5 CCNc1nc(Cl)nc(NC(C)(C)C)n1 InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is identical to the substance Terbuthylazine 227-637-9 5915-41-3 N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine Terbuthylazine C9H16ClN5 CCNc1nc(Cl)nc(NC(C)(C)C)n1 InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is identical to the substance Terbuthylazine 227-637-9 5915-41-3 N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine Terbuthylazine C9H16ClN5 CCNc1nc(Cl)nc(NC(C)(C)C)n1 InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is identical to the substance Terbuthylazine 227-637-9 5915-41-3 N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine Terbuthylazine C9H16ClN5 CCNc1nc(Cl)nc(NC(C)(C)C)n1 InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is identical to the substance Terbuthylazine 227-637-9 5915-41-3 N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine Terbuthylazine C9H16ClN5 CCNc1nc(Cl)nc(NC(C)(C)C)n1 InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is identical to the substance Terbuthylazine 227-637-9 5915-41-3 N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine Terbuthylazine C9H16ClN5 CCNc1nc(Cl)nc(NC(C)(C)C)n1 InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is identical to the substance Terbuthylazine 227-637-9 5915-41-3 N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine Terbuthylazine C9H16ClN5 CCNc1nc(Cl)nc(NC(C)(C)C)n1 InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is identical to the substance Terbuthylazine 227-637-9 5915-41-3 N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine Terbuthylazine C9H16ClN5 CCNc1nc(Cl)nc(NC(C)(C)C)n1 InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is identical to the substance Terbuthylazine 227-637-9 5915-41-3 N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine Terbuthylazine C9H16ClN5 CCNc1nc(Cl)nc(NC(C)(C)C)n1 InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is identical to the substance Terbuthylazine 227-637-9 5915-41-3 N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine Terbuthylazine C9H16ClN5 CCNc1nc(Cl)nc(NC(C)(C)C)n1 InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is identical to the substance Terbuthylazine 227-637-9 5915-41-3 N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine Terbuthylazine C9H16ClN5 CCNc1nc(Cl)nc(NC(C)(C)C)n1 InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is identical to the substance Terbuthylazine 227-637-9 5915-41-3 N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine Terbuthylazine C9H16ClN5 CCNc1nc(Cl)nc(NC(C)(C)C)n1 InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Positive RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is identical to the substance Terbuthylazine 227-637-9 5915-41-3 N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine Terbuthylazine C9H16ClN5 CCNc1nc(Cl)nc(NC(C)(C)C)n1 InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is identical to the substance Terbuthylazine 227-637-9 5915-41-3 N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine Terbuthylazine C9H16ClN5 CCNc1nc(Cl)nc(NC(C)(C)C)n1 InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is identical to the substance Terbuthylazine 227-637-9 5915-41-3 N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine Terbuthylazine C9H16ClN5 CCNc1nc(Cl)nc(NC(C)(C)C)n1 InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Swiss 10 Male/Female oral: gavage 72.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity$indirect evidence-systemic toxicity RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is identical to the substance Terbuthylazine 227-637-9 5915-41-3 N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine Terbuthylazine C9H16ClN5 CCNc1nc(Cl)nc(NC(C)(C)C)n1 InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Swiss 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity$indirect evidence-systemic toxicity RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is identical to the substance Terbuthylazine 227-637-9 5915-41-3 N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine Terbuthylazine C9H16ClN5 CCNc1nc(Cl)nc(NC(C)(C)C)n1 InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Swiss 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity$indirect evidence-systemic toxicity RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Desethyl-hydroxy-terbuthylazine 4-amino-6-(tert-butylamino)-1,3,5-triazin-2-ol Desethyl-hydroxy-terbuthylazine C7H13N5O Nc1nc(NC(C)(C)C)nc(O)n1 InChI=1S/C7H13N5O/c1-7(2,3)12-5-9-4(8)10-6(13)11-5/h1-3H3,(H4,8,9,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Desethyl-hydroxy-terbuthylazine 4-amino-6-(tert-butylamino)-1,3,5-triazin-2-ol Desethyl-hydroxy-terbuthylazine C7H13N5O Nc1nc(NC(C)(C)C)nc(O)n1 InChI=1S/C7H13N5O/c1-7(2,3)12-5-9-4(8)10-6(13)11-5/h1-3H3,(H4,8,9,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Desethyl-hydroxy-terbuthylazine 4-amino-6-(tert-butylamino)-1,3,5-triazin-2-ol Desethyl-hydroxy-terbuthylazine C7H13N5O Nc1nc(NC(C)(C)C)nc(O)n1 InChI=1S/C7H13N5O/c1-7(2,3)12-5-9-4(8)10-6(13)11-5/h1-3H3,(H4,8,9,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Desethyl-hydroxy-terbuthylazine 4-amino-6-(tert-butylamino)-1,3,5-triazin-2-ol Desethyl-hydroxy-terbuthylazine C7H13N5O Nc1nc(NC(C)(C)C)nc(O)n1 InChI=1S/C7H13N5O/c1-7(2,3)12-5-9-4(8)10-6(13)11-5/h1-3H3,(H4,8,9,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Desethyl-hydroxy-terbuthylazine 4-amino-6-(tert-butylamino)-1,3,5-triazin-2-ol Desethyl-hydroxy-terbuthylazine C7H13N5O Nc1nc(NC(C)(C)C)nc(O)n1 InChI=1S/C7H13N5O/c1-7(2,3)12-5-9-4(8)10-6(13)11-5/h1-3H3,(H4,8,9,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Desethyl-hydroxy-terbuthylazine 4-amino-6-(tert-butylamino)-1,3,5-triazin-2-ol Desethyl-hydroxy-terbuthylazine C7H13N5O Nc1nc(NC(C)(C)C)nc(O)n1 InChI=1S/C7H13N5O/c1-7(2,3)12-5-9-4(8)10-6(13)11-5/h1-3H3,(H4,8,9,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Desethyl-hydroxy-terbuthylazine 4-amino-6-(tert-butylamino)-1,3,5-triazin-2-ol Desethyl-hydroxy-terbuthylazine C7H13N5O Nc1nc(NC(C)(C)C)nc(O)n1 InChI=1S/C7H13N5O/c1-7(2,3)12-5-9-4(8)10-6(13)11-5/h1-3H3,(H4,8,9,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Desethyl-hydroxy-terbuthylazine 4-amino-6-(tert-butylamino)-1,3,5-triazin-2-ol Desethyl-hydroxy-terbuthylazine C7H13N5O Nc1nc(NC(C)(C)C)nc(O)n1 InChI=1S/C7H13N5O/c1-7(2,3)12-5-9-4(8)10-6(13)11-5/h1-3H3,(H4,8,9,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Desethyl-hydroxy-terbuthylazine 4-amino-6-(tert-butylamino)-1,3,5-triazin-2-ol Desethyl-hydroxy-terbuthylazine C7H13N5O Nc1nc(NC(C)(C)C)nc(O)n1 InChI=1S/C7H13N5O/c1-7(2,3)12-5-9-4(8)10-6(13)11-5/h1-3H3,(H4,8,9,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Desethyl-hydroxy-terbuthylazine 4-amino-6-(tert-butylamino)-1,3,5-triazin-2-ol Desethyl-hydroxy-terbuthylazine C7H13N5O Nc1nc(NC(C)(C)C)nc(O)n1 InChI=1S/C7H13N5O/c1-7(2,3)12-5-9-4(8)10-6(13)11-5/h1-3H3,(H4,8,9,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Desethyl-hydroxy-terbuthylazine 4-amino-6-(tert-butylamino)-1,3,5-triazin-2-ol Desethyl-hydroxy-terbuthylazine C7H13N5O Nc1nc(NC(C)(C)C)nc(O)n1 InChI=1S/C7H13N5O/c1-7(2,3)12-5-9-4(8)10-6(13)11-5/h1-3H3,(H4,8,9,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Desethyl-hydroxy-terbuthylazine 4-amino-6-(tert-butylamino)-1,3,5-triazin-2-ol Desethyl-hydroxy-terbuthylazine C7H13N5O Nc1nc(NC(C)(C)C)nc(O)n1 InChI=1S/C7H13N5O/c1-7(2,3)12-5-9-4(8)10-6(13)11-5/h1-3H3,(H4,8,9,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Desethyl-hydroxy-terbuthylazine 4-amino-6-(tert-butylamino)-1,3,5-triazin-2-ol Desethyl-hydroxy-terbuthylazine C7H13N5O Nc1nc(NC(C)(C)C)nc(O)n1 InChI=1S/C7H13N5O/c1-7(2,3)12-5-9-4(8)10-6(13)11-5/h1-3H3,(H4,8,9,10,11,12,13) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative large colonies RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Desethyl-hydroxy-terbuthylazine 4-amino-6-(tert-butylamino)-1,3,5-triazin-2-ol Desethyl-hydroxy-terbuthylazine C7H13N5O Nc1nc(NC(C)(C)C)nc(O)n1 InChI=1S/C7H13N5O/c1-7(2,3)12-5-9-4(8)10-6(13)11-5/h1-3H3,(H4,8,9,10,11,12,13) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative large colonies RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Desethyl-hydroxy-terbuthylazine 4-amino-6-(tert-butylamino)-1,3,5-triazin-2-ol Desethyl-hydroxy-terbuthylazine C7H13N5O Nc1nc(NC(C)(C)C)nc(O)n1 InChI=1S/C7H13N5O/c1-7(2,3)12-5-9-4(8)10-6(13)11-5/h1-3H3,(H4,8,9,10,11,12,13) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative small colonies RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Desethyl-hydroxy-terbuthylazine 4-amino-6-(tert-butylamino)-1,3,5-triazin-2-ol Desethyl-hydroxy-terbuthylazine C7H13N5O Nc1nc(NC(C)(C)C)nc(O)n1 InChI=1S/C7H13N5O/c1-7(2,3)12-5-9-4(8)10-6(13)11-5/h1-3H3,(H4,8,9,10,11,12,13) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative small colonies RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Desethyl-hydroxy-terbuthylazine 4-amino-6-(tert-butylamino)-1,3,5-triazin-2-ol Desethyl-hydroxy-terbuthylazine C7H13N5O Nc1nc(NC(C)(C)C)nc(O)n1 InChI=1S/C7H13N5O/c1-7(2,3)12-5-9-4(8)10-6(13)11-5/h1-3H3,(H4,8,9,10,11,12,13) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Desethyl-hydroxy-terbuthylazine 4-amino-6-(tert-butylamino)-1,3,5-triazin-2-ol Desethyl-hydroxy-terbuthylazine C7H13N5O Nc1nc(NC(C)(C)C)nc(O)n1 InChI=1S/C7H13N5O/c1-7(2,3)12-5-9-4(8)10-6(13)11-5/h1-3H3,(H4,8,9,10,11,12,13) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Hydroxy-terbuthylazine 4-(tert-butylamino)-6-(ethylamino)-1,3,5-triazin-2-ol Not in list C9H17N5O Oc1nc(NCC)nc(NC(C)(C)C)n1 InChI=1S/C9H17N5O/c1-5-10-6-11-7(13-8(15)12-6)14-9(2,3)4/h5H2,1-4H3,(H3,10,11,12,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Hydroxy-terbuthylazine 4-(tert-butylamino)-6-(ethylamino)-1,3,5-triazin-2-ol Not in list C9H17N5O Oc1nc(NCC)nc(NC(C)(C)C)n1 InChI=1S/C9H17N5O/c1-5-10-6-11-7(13-8(15)12-6)14-9(2,3)4/h5H2,1-4H3,(H3,10,11,12,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Hydroxy-terbuthylazine 4-(tert-butylamino)-6-(ethylamino)-1,3,5-triazin-2-ol Not in list C9H17N5O Oc1nc(NCC)nc(NC(C)(C)C)n1 InChI=1S/C9H17N5O/c1-5-10-6-11-7(13-8(15)12-6)14-9(2,3)4/h5H2,1-4H3,(H3,10,11,12,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Hydroxy-terbuthylazine 4-(tert-butylamino)-6-(ethylamino)-1,3,5-triazin-2-ol Not in list C9H17N5O Oc1nc(NCC)nc(NC(C)(C)C)n1 InChI=1S/C9H17N5O/c1-5-10-6-11-7(13-8(15)12-6)14-9(2,3)4/h5H2,1-4H3,(H3,10,11,12,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Hydroxy-terbuthylazine 4-(tert-butylamino)-6-(ethylamino)-1,3,5-triazin-2-ol Not in list C9H17N5O Oc1nc(NCC)nc(NC(C)(C)C)n1 InChI=1S/C9H17N5O/c1-5-10-6-11-7(13-8(15)12-6)14-9(2,3)4/h5H2,1-4H3,(H3,10,11,12,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Hydroxy-terbuthylazine 4-(tert-butylamino)-6-(ethylamino)-1,3,5-triazin-2-ol Not in list C9H17N5O Oc1nc(NCC)nc(NC(C)(C)C)n1 InChI=1S/C9H17N5O/c1-5-10-6-11-7(13-8(15)12-6)14-9(2,3)4/h5H2,1-4H3,(H3,10,11,12,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Hydroxy-terbuthylazine 4-(tert-butylamino)-6-(ethylamino)-1,3,5-triazin-2-ol Not in list C9H17N5O Oc1nc(NCC)nc(NC(C)(C)C)n1 InChI=1S/C9H17N5O/c1-5-10-6-11-7(13-8(15)12-6)14-9(2,3)4/h5H2,1-4H3,(H3,10,11,12,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Hydroxy-terbuthylazine 4-(tert-butylamino)-6-(ethylamino)-1,3,5-triazin-2-ol Not in list C9H17N5O Oc1nc(NCC)nc(NC(C)(C)C)n1 InChI=1S/C9H17N5O/c1-5-10-6-11-7(13-8(15)12-6)14-9(2,3)4/h5H2,1-4H3,(H3,10,11,12,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Hydroxy-terbuthylazine 4-(tert-butylamino)-6-(ethylamino)-1,3,5-triazin-2-ol Not in list C9H17N5O Oc1nc(NCC)nc(NC(C)(C)C)n1 InChI=1S/C9H17N5O/c1-5-10-6-11-7(13-8(15)12-6)14-9(2,3)4/h5H2,1-4H3,(H3,10,11,12,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Hydroxy-terbuthylazine 4-(tert-butylamino)-6-(ethylamino)-1,3,5-triazin-2-ol Not in list C9H17N5O Oc1nc(NCC)nc(NC(C)(C)C)n1 InChI=1S/C9H17N5O/c1-5-10-6-11-7(13-8(15)12-6)14-9(2,3)4/h5H2,1-4H3,(H3,10,11,12,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Hydroxy-terbuthylazine 4-(tert-butylamino)-6-(ethylamino)-1,3,5-triazin-2-ol Not in list C9H17N5O Oc1nc(NCC)nc(NC(C)(C)C)n1 InChI=1S/C9H17N5O/c1-5-10-6-11-7(13-8(15)12-6)14-9(2,3)4/h5H2,1-4H3,(H3,10,11,12,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Hydroxy-terbuthylazine 4-(tert-butylamino)-6-(ethylamino)-1,3,5-triazin-2-ol Not in list C9H17N5O Oc1nc(NCC)nc(NC(C)(C)C)n1 InChI=1S/C9H17N5O/c1-5-10-6-11-7(13-8(15)12-6)14-9(2,3)4/h5H2,1-4H3,(H3,10,11,12,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Hydroxy-terbuthylazine 4-(tert-butylamino)-6-(ethylamino)-1,3,5-triazin-2-ol Not in list C9H17N5O Oc1nc(NCC)nc(NC(C)(C)C)n1 InChI=1S/C9H17N5O/c1-5-10-6-11-7(13-8(15)12-6)14-9(2,3)4/h5H2,1-4H3,(H3,10,11,12,13,14,15) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative large colonies RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Hydroxy-terbuthylazine 4-(tert-butylamino)-6-(ethylamino)-1,3,5-triazin-2-ol Not in list C9H17N5O Oc1nc(NCC)nc(NC(C)(C)C)n1 InChI=1S/C9H17N5O/c1-5-10-6-11-7(13-8(15)12-6)14-9(2,3)4/h5H2,1-4H3,(H3,10,11,12,13,14,15) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative small colonies RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Hydroxy-terbuthylazine 4-(tert-butylamino)-6-(ethylamino)-1,3,5-triazin-2-ol Not in list C9H17N5O Oc1nc(NCC)nc(NC(C)(C)C)n1 InChI=1S/C9H17N5O/c1-5-10-6-11-7(13-8(15)12-6)14-9(2,3)4/h5H2,1-4H3,(H3,10,11,12,13,14,15) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative small colonies RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Hydroxy-terbuthylazine 4-(tert-butylamino)-6-(ethylamino)-1,3,5-triazin-2-ol Not in list C9H17N5O Oc1nc(NCC)nc(NC(C)(C)C)n1 InChI=1S/C9H17N5O/c1-5-10-6-11-7(13-8(15)12-6)14-9(2,3)4/h5H2,1-4H3,(H3,10,11,12,13,14,15) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative large colonies RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Hydroxy-terbuthylazine 4-(tert-butylamino)-6-(ethylamino)-1,3,5-triazin-2-ol Not in list C9H17N5O Oc1nc(NCC)nc(NC(C)(C)C)n1 InChI=1S/C9H17N5O/c1-5-10-6-11-7(13-8(15)12-6)14-9(2,3)4/h5H2,1-4H3,(H3,10,11,12,13,14,15) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Hydroxy-terbuthylazine 4-(tert-butylamino)-6-(ethylamino)-1,3,5-triazin-2-ol Not in list C9H17N5O Oc1nc(NCC)nc(NC(C)(C)C)n1 InChI=1S/C9H17N5O/c1-5-10-6-11-7(13-8(15)12-6)14-9(2,3)4/h5H2,1-4H3,(H3,10,11,12,13,14,15) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance 2-Chloro-4,6-diamino-s-triazin 222-260-6 3397-62-4 6-Chloro-1,3,5-triazine-2,4-diamine Atrazine, Desethyl-Desisopropyl- C3H4ClN5 C1(=NC(=NC(=N1)Cl)N)N InChI=1S/C3H4ClN5/c4-1-7-2(5)9-3(6)8-1/h(H4,5,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance 2-Chloro-4,6-diamino-s-triazin 222-260-6 3397-62-4 6-Chloro-1,3,5-triazine-2,4-diamine Atrazine, Desethyl-Desisopropyl- C3H4ClN5 C1(=NC(=NC(=N1)Cl)N)N InChI=1S/C3H4ClN5/c4-1-7-2(5)9-3(6)8-1/h(H4,5,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance 2-Chloro-4,6-diamino-s-triazin 222-260-6 3397-62-4 6-Chloro-1,3,5-triazine-2,4-diamine Atrazine, Desethyl-Desisopropyl- C3H4ClN5 C1(=NC(=NC(=N1)Cl)N)N InChI=1S/C3H4ClN5/c4-1-7-2(5)9-3(6)8-1/h(H4,5,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance 2-Chloro-4,6-diamino-s-triazin 222-260-6 3397-62-4 6-Chloro-1,3,5-triazine-2,4-diamine Atrazine, Desethyl-Desisopropyl- C3H4ClN5 C1(=NC(=NC(=N1)Cl)N)N InChI=1S/C3H4ClN5/c4-1-7-2(5)9-3(6)8-1/h(H4,5,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance 2-Chloro-4,6-diamino-s-triazin 222-260-6 3397-62-4 6-Chloro-1,3,5-triazine-2,4-diamine Atrazine, Desethyl-Desisopropyl- C3H4ClN5 C1(=NC(=NC(=N1)Cl)N)N InChI=1S/C3H4ClN5/c4-1-7-2(5)9-3(6)8-1/h(H4,5,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance 2-Chloro-4,6-diamino-s-triazin 222-260-6 3397-62-4 6-Chloro-1,3,5-triazine-2,4-diamine Atrazine, Desethyl-Desisopropyl- C3H4ClN5 C1(=NC(=NC(=N1)Cl)N)N InChI=1S/C3H4ClN5/c4-1-7-2(5)9-3(6)8-1/h(H4,5,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance 2-Chloro-4,6-diamino-s-triazin 222-260-6 3397-62-4 6-Chloro-1,3,5-triazine-2,4-diamine Atrazine, Desethyl-Desisopropyl- C3H4ClN5 C1(=NC(=NC(=N1)Cl)N)N InChI=1S/C3H4ClN5/c4-1-7-2(5)9-3(6)8-1/h(H4,5,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance 2-Chloro-4,6-diamino-s-triazin 222-260-6 3397-62-4 6-Chloro-1,3,5-triazine-2,4-diamine Atrazine, Desethyl-Desisopropyl- C3H4ClN5 C1(=NC(=NC(=N1)Cl)N)N InChI=1S/C3H4ClN5/c4-1-7-2(5)9-3(6)8-1/h(H4,5,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance 2-Chloro-4,6-diamino-s-triazin 222-260-6 3397-62-4 6-Chloro-1,3,5-triazine-2,4-diamine Atrazine, Desethyl-Desisopropyl- C3H4ClN5 C1(=NC(=NC(=N1)Cl)N)N InChI=1S/C3H4ClN5/c4-1-7-2(5)9-3(6)8-1/h(H4,5,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Tif:MAGf(SPF) 16 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance 2-Chloro-4,6-diamino-s-triazin 222-260-6 3397-62-4 6-Chloro-1,3,5-triazine-2,4-diamine Atrazine, Desethyl-Desisopropyl- C3H4ClN5 C1(=NC(=NC(=N1)Cl)N)N InChI=1S/C3H4ClN5/c4-1-7-2(5)9-3(6)8-1/h(H4,5,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Tif:MAGf(SPF) 16 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance 2-Chloro-4,6-diamino-s-triazin 222-260-6 3397-62-4 6-Chloro-1,3,5-triazine-2,4-diamine Atrazine, Desethyl-Desisopropyl- C3H4ClN5 C1(=NC(=NC(=N1)Cl)N)N InChI=1S/C3H4ClN5/c4-1-7-2(5)9-3(6)8-1/h(H4,5,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Tif:MAGf(SPF) Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance 2-Chloro-4,6-diamino-s-triazin 222-260-6 3397-62-4 6-Chloro-1,3,5-triazine-2,4-diamine Atrazine, Desethyl-Desisopropyl- C3H4ClN5 C1(=NC(=NC(=N1)Cl)N)N InChI=1S/C3H4ClN5/c4-1-7-2(5)9-3(6)8-1/h(H4,5,6,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Tif:MAGf(SPF) 16 Male/Female oral: gavage 16.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Desethyl-terbuthylazine 30125-63-4 2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine Terbuthylazine, Desethyl- C7H12ClN5 CC(C)(C)NC1=NC(=NC(=N1)N)Cl InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Desethyl-terbuthylazine 30125-63-4 2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine Terbuthylazine, Desethyl- C7H12ClN5 CC(C)(C)NC1=NC(=NC(=N1)N)Cl InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Desethyl-terbuthylazine 30125-63-4 2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine Terbuthylazine, Desethyl- C7H12ClN5 CC(C)(C)NC1=NC(=NC(=N1)N)Cl InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Desethyl-terbuthylazine 30125-63-4 2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine Terbuthylazine, Desethyl- C7H12ClN5 CC(C)(C)NC1=NC(=NC(=N1)N)Cl InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Desethyl-terbuthylazine 30125-63-4 2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine Terbuthylazine, Desethyl- C7H12ClN5 CC(C)(C)NC1=NC(=NC(=N1)N)Cl InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Desethyl-terbuthylazine 30125-63-4 2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine Terbuthylazine, Desethyl- C7H12ClN5 CC(C)(C)NC1=NC(=NC(=N1)N)Cl InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Desethyl-terbuthylazine 30125-63-4 2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine Terbuthylazine, Desethyl- C7H12ClN5 CC(C)(C)NC1=NC(=NC(=N1)N)Cl InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Desethyl-terbuthylazine 30125-63-4 2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine Terbuthylazine, Desethyl- C7H12ClN5 CC(C)(C)NC1=NC(=NC(=N1)N)Cl InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Desethyl-terbuthylazine 30125-63-4 2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine Terbuthylazine, Desethyl- C7H12ClN5 CC(C)(C)NC1=NC(=NC(=N1)N)Cl InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Desethyl-terbuthylazine 30125-63-4 2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine Terbuthylazine, Desethyl- C7H12ClN5 CC(C)(C)NC1=NC(=NC(=N1)N)Cl InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Desethyl-terbuthylazine 30125-63-4 2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine Terbuthylazine, Desethyl- C7H12ClN5 CC(C)(C)NC1=NC(=NC(=N1)N)Cl InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Desethyl-terbuthylazine 30125-63-4 2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine Terbuthylazine, Desethyl- C7H12ClN5 CC(C)(C)NC1=NC(=NC(=N1)N)Cl InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Desethyl-terbuthylazine 30125-63-4 2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine Terbuthylazine, Desethyl- C7H12ClN5 CC(C)(C)NC1=NC(=NC(=N1)N)Cl InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Desethyl-terbuthylazine 30125-63-4 2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine Terbuthylazine, Desethyl- C7H12ClN5 CC(C)(C)NC1=NC(=NC(=N1)N)Cl InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Terbuthylazine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is identical to the substance Terbuthylazine 227-637-9 5915-41-3 N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine Terbuthylazine C9H16ClN5 CCNc1nc(Cl)nc(NC(C)(C)C)n1 InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is identical to the substance Terbuthylazine 227-637-9 5915-41-3 N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine Terbuthylazine C9H16ClN5 CCNc1nc(Cl)nc(NC(C)(C)C)n1 InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is identical to the substance Terbuthylazine 227-637-9 5915-41-3 N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine Terbuthylazine C9H16ClN5 CCNc1nc(Cl)nc(NC(C)(C)C)n1 InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is identical to the substance Terbuthylazine 227-637-9 5915-41-3 N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine Terbuthylazine C9H16ClN5 CCNc1nc(Cl)nc(NC(C)(C)C)n1 InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is identical to the substance Terbuthylazine 227-637-9 5915-41-3 N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine Terbuthylazine C9H16ClN5 CCNc1nc(Cl)nc(NC(C)(C)C)n1 InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is identical to the substance Terbuthylazine 227-637-9 5915-41-3 N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine Terbuthylazine C9H16ClN5 CCNc1nc(Cl)nc(NC(C)(C)C)n1 InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is identical to the substance Terbuthylazine 227-637-9 5915-41-3 N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine Terbuthylazine C9H16ClN5 CCNc1nc(Cl)nc(NC(C)(C)C)n1 InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is identical to the substance Terbuthylazine 227-637-9 5915-41-3 N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine Terbuthylazine C9H16ClN5 CCNc1nc(Cl)nc(NC(C)(C)C)n1 InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is identical to the substance Terbuthylazine 227-637-9 5915-41-3 N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine Terbuthylazine C9H16ClN5 CCNc1nc(Cl)nc(NC(C)(C)C)n1 InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is identical to the substance Terbuthylazine 227-637-9 5915-41-3 N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine Terbuthylazine C9H16ClN5 CCNc1nc(Cl)nc(NC(C)(C)C)n1 InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Desethyl-terbuthylazine 30125-63-4 2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine Terbuthylazine, Desethyl- C7H12ClN5 CC(C)(C)NC1=NC(=NC(=N1)N)Cl InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Desethyl-terbuthylazine 30125-63-4 2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine Terbuthylazine, Desethyl- C7H12ClN5 CC(C)(C)NC1=NC(=NC(=N1)N)Cl InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Desethyl-terbuthylazine 30125-63-4 2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine Terbuthylazine, Desethyl- C7H12ClN5 CC(C)(C)NC1=NC(=NC(=N1)N)Cl InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Desethyl-terbuthylazine 30125-63-4 2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine Terbuthylazine, Desethyl- C7H12ClN5 CC(C)(C)NC1=NC(=NC(=N1)N)Cl InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Desethyl-terbuthylazine 30125-63-4 2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine Terbuthylazine, Desethyl- C7H12ClN5 CC(C)(C)NC1=NC(=NC(=N1)N)Cl InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Desethyl-terbuthylazine 30125-63-4 2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine Terbuthylazine, Desethyl- C7H12ClN5 CC(C)(C)NC1=NC(=NC(=N1)N)Cl InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Desethyl-terbuthylazine 30125-63-4 2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine Terbuthylazine, Desethyl- C7H12ClN5 CC(C)(C)NC1=NC(=NC(=N1)N)Cl InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Desethyl-terbuthylazine 30125-63-4 2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine Terbuthylazine, Desethyl- C7H12ClN5 CC(C)(C)NC1=NC(=NC(=N1)N)Cl InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Desethyl-terbuthylazine 30125-63-4 2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine Terbuthylazine, Desethyl- C7H12ClN5 CC(C)(C)NC1=NC(=NC(=N1)N)Cl InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Desethyl-terbuthylazine 30125-63-4 2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine Terbuthylazine, Desethyl- C7H12ClN5 CC(C)(C)NC1=NC(=NC(=N1)N)Cl InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Desethyl-terbuthylazine 30125-63-4 2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine Terbuthylazine, Desethyl- C7H12ClN5 CC(C)(C)NC1=NC(=NC(=N1)N)Cl InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Positive small colonies RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Desethyl-terbuthylazine 30125-63-4 2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine Terbuthylazine, Desethyl- C7H12ClN5 CC(C)(C)NC1=NC(=NC(=N1)N)Cl InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Positive small colonies RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Desethyl-terbuthylazine 30125-63-4 2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine Terbuthylazine, Desethyl- C7H12ClN5 CC(C)(C)NC1=NC(=NC(=N1)N)Cl InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Positive large colonies RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Desethyl-terbuthylazine 30125-63-4 2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine Terbuthylazine, Desethyl- C7H12ClN5 CC(C)(C)NC1=NC(=NC(=N1)N)Cl InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Positive large colonies RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Desethyl-terbuthylazine 30125-63-4 2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine Terbuthylazine, Desethyl- C7H12ClN5 CC(C)(C)NC1=NC(=NC(=N1)N)Cl InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable Rat (as animal) Alpk:APf SD Rat 10 Male oral: unspecified 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Desethyl-terbuthylazine 30125-63-4 2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine Terbuthylazine, Desethyl- C7H12ClN5 CC(C)(C)NC1=NC(=NC(=N1)N)Cl InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable Rat (as animal) Alpk:APf SD Rat 10 Male oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Desethyl-terbuthylazine 30125-63-4 2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine Terbuthylazine, Desethyl- C7H12ClN5 CC(C)(C)NC1=NC(=NC(=N1)N)Cl InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Alpk:APf SD Rat 6 Male Not reported 2.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance Desethyl-terbuthylazine 30125-63-4 2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine Terbuthylazine, Desethyl- C7H12ClN5 CC(C)(C)NC1=NC(=NC(=N1)N)Cl InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Alpk:APf SD Rat 6 Male Not reported 16.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance 2,6-dihydroxy-7,7-dimethyl-7,8-dihydroimidazo[1,2-a][1,3,5]triazin-4(6H)-one 2,6-dihydroxy-7,7-dimethyl-7,8-dihydroimidazo[1,2-a][1,3,5]triazin-4(6H)-one Not in list C7H10N4O3 O=C1N=C(O)N=C2NC(C)(C)C(O)N12 InChI=1S/C7H10N4O3/c1-7(2)3(12)11-4(10-7)8-5(13)9-6(11)14/h3,12H,1-2H3,(H2,8,9,10,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance 2,6-dihydroxy-7,7-dimethyl-7,8-dihydroimidazo[1,2-a][1,3,5]triazin-4(6H)-one 2,6-dihydroxy-7,7-dimethyl-7,8-dihydroimidazo[1,2-a][1,3,5]triazin-4(6H)-one Not in list C7H10N4O3 O=C1N=C(O)N=C2NC(C)(C)C(O)N12 InChI=1S/C7H10N4O3/c1-7(2)3(12)11-4(10-7)8-5(13)9-6(11)14/h3,12H,1-2H3,(H2,8,9,10,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance 2,6-dihydroxy-7,7-dimethyl-7,8-dihydroimidazo[1,2-a][1,3,5]triazin-4(6H)-one 2,6-dihydroxy-7,7-dimethyl-7,8-dihydroimidazo[1,2-a][1,3,5]triazin-4(6H)-one Not in list C7H10N4O3 O=C1N=C(O)N=C2NC(C)(C)C(O)N12 InChI=1S/C7H10N4O3/c1-7(2)3(12)11-4(10-7)8-5(13)9-6(11)14/h3,12H,1-2H3,(H2,8,9,10,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance 2,6-dihydroxy-7,7-dimethyl-7,8-dihydroimidazo[1,2-a][1,3,5]triazin-4(6H)-one 2,6-dihydroxy-7,7-dimethyl-7,8-dihydroimidazo[1,2-a][1,3,5]triazin-4(6H)-one Not in list C7H10N4O3 O=C1N=C(O)N=C2NC(C)(C)C(O)N12 InChI=1S/C7H10N4O3/c1-7(2)3(12)11-4(10-7)8-5(13)9-6(11)14/h3,12H,1-2H3,(H2,8,9,10,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance 2,6-dihydroxy-7,7-dimethyl-7,8-dihydroimidazo[1,2-a][1,3,5]triazin-4(6H)-one 2,6-dihydroxy-7,7-dimethyl-7,8-dihydroimidazo[1,2-a][1,3,5]triazin-4(6H)-one Not in list C7H10N4O3 O=C1N=C(O)N=C2NC(C)(C)C(O)N12 InChI=1S/C7H10N4O3/c1-7(2)3(12)11-4(10-7)8-5(13)9-6(11)14/h3,12H,1-2H3,(H2,8,9,10,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes without Negative RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance 2,6-dihydroxy-7,7-dimethyl-7,8-dihydroimidazo[1,2-a][1,3,5]triazin-4(6H)-one 2,6-dihydroxy-7,7-dimethyl-7,8-dihydroimidazo[1,2-a][1,3,5]triazin-4(6H)-one Not in list C7H10N4O3 O=C1N=C(O)N=C2NC(C)(C)C(O)N12 InChI=1S/C7H10N4O3/c1-7(2)3(12)11-4(10-7)8-5(13)9-6(11)14/h3,12H,1-2H3,(H2,8,9,10,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes with Negative RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance 2,6-dihydroxy-7,7-dimethyl-7,8-dihydroimidazo[1,2-a][1,3,5]triazin-4(6H)-one 2,6-dihydroxy-7,7-dimethyl-7,8-dihydroimidazo[1,2-a][1,3,5]triazin-4(6H)-one Not in list C7H10N4O3 O=C1N=C(O)N=C2NC(C)(C)C(O)N12 InChI=1S/C7H10N4O3/c1-7(2)3(12)11-4(10-7)8-5(13)9-6(11)14/h3,12H,1-2H3,(H2,8,9,10,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance 2,6-dihydroxy-7,7-dimethyl-7,8-dihydroimidazo[1,2-a][1,3,5]triazin-4(6H)-one 2,6-dihydroxy-7,7-dimethyl-7,8-dihydroimidazo[1,2-a][1,3,5]triazin-4(6H)-one Not in list C7H10N4O3 O=C1N=C(O)N=C2NC(C)(C)C(O)N12 InChI=1S/C7H10N4O3/c1-7(2)3(12)11-4(10-7)8-5(13)9-6(11)14/h3,12H,1-2H3,(H2,8,9,10,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes with Negative RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance 2,6-dihydroxy-7,7-dimethyl-7,8-dihydroimidazo[1,2-a][1,3,5]triazin-4(6H)-one 2,6-dihydroxy-7,7-dimethyl-7,8-dihydroimidazo[1,2-a][1,3,5]triazin-4(6H)-one Not in list C7H10N4O3 O=C1N=C(O)N=C2NC(C)(C)C(O)N12 InChI=1S/C7H10N4O3/c1-7(2)3(12)11-4(10-7)8-5(13)9-6(11)14/h3,12H,1-2H3,(H2,8,9,10,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes without Negative RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance 2,6-dihydroxy-7,7-dimethyl-7,8-dihydroimidazo[1,2-a][1,3,5]triazin-4(6H)-one 2,6-dihydroxy-7,7-dimethyl-7,8-dihydroimidazo[1,2-a][1,3,5]triazin-4(6H)-one Not in list C7H10N4O3 O=C1N=C(O)N=C2NC(C)(C)C(O)N12 InChI=1S/C7H10N4O3/c1-7(2)3(12)11-4(10-7)8-5(13)9-6(11)14/h3,12H,1-2H3,(H2,8,9,10,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance 2,6-dihydroxy-7,7-dimethyl-7,8-dihydroimidazo[1,2-a][1,3,5]triazin-4(6H)-one 2,6-dihydroxy-7,7-dimethyl-7,8-dihydroimidazo[1,2-a][1,3,5]triazin-4(6H)-one Not in list C7H10N4O3 O=C1N=C(O)N=C2NC(C)(C)C(O)N12 InChI=1S/C7H10N4O3/c1-7(2)3(12)11-4(10-7)8-5(13)9-6(11)14/h3,12H,1-2H3,(H2,8,9,10,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance 2,6-dihydroxy-7,7-dimethyl-7,8-dihydroimidazo[1,2-a][1,3,5]triazin-4(6H)-one 2,6-dihydroxy-7,7-dimethyl-7,8-dihydroimidazo[1,2-a][1,3,5]triazin-4(6H)-one Not in list C7H10N4O3 O=C1N=C(O)N=C2NC(C)(C)C(O)N12 InChI=1S/C7H10N4O3/c1-7(2)3(12)11-4(10-7)8-5(13)9-6(11)14/h3,12H,1-2H3,(H2,8,9,10,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance 2,6-dihydroxy-7,7-dimethyl-7,8-dihydroimidazo[1,2-a][1,3,5]triazin-4(6H)-one 2,6-dihydroxy-7,7-dimethyl-7,8-dihydroimidazo[1,2-a][1,3,5]triazin-4(6H)-one Not in list C7H10N4O3 O=C1N=C(O)N=C2NC(C)(C)C(O)N12 InChI=1S/C7H10N4O3/c1-7(2)3(12)11-4(10-7)8-5(13)9-6(11)14/h3,12H,1-2H3,(H2,8,9,10,13,14) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance 2,6-dihydroxy-7,7-dimethyl-7,8-dihydroimidazo[1,2-a][1,3,5]triazin-4(6H)-one 2,6-dihydroxy-7,7-dimethyl-7,8-dihydroimidazo[1,2-a][1,3,5]triazin-4(6H)-one Not in list C7H10N4O3 O=C1N=C(O)N=C2NC(C)(C)C(O)N12 InChI=1S/C7H10N4O3/c1-7(2)3(12)11-4(10-7)8-5(13)9-6(11)14/h3,12H,1-2H3,(H2,8,9,10,13,14) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance 6-(tert-butylamino)-1,3,5-triazine-2,4-diol 6-(tert-butylamino)-1,3,5-triazine-2,4-diol Not in list C7H12N4O2 Oc1nc(NC(C)(C)C)nc(O)n1 InChI=1S/C7H12N4O2/c1-7(2,3)11-4-8-5(12)10-6(13)9-4/h1-3H3,(H3,8,9,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes with Negative RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance 6-(tert-butylamino)-1,3,5-triazine-2,4-diol 6-(tert-butylamino)-1,3,5-triazine-2,4-diol Not in list C7H12N4O2 Oc1nc(NC(C)(C)C)nc(O)n1 InChI=1S/C7H12N4O2/c1-7(2,3)11-4-8-5(12)10-6(13)9-4/h1-3H3,(H3,8,9,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance 6-(tert-butylamino)-1,3,5-triazine-2,4-diol 6-(tert-butylamino)-1,3,5-triazine-2,4-diol Not in list C7H12N4O2 Oc1nc(NC(C)(C)C)nc(O)n1 InChI=1S/C7H12N4O2/c1-7(2,3)11-4-8-5(12)10-6(13)9-4/h1-3H3,(H3,8,9,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance 6-(tert-butylamino)-1,3,5-triazine-2,4-diol 6-(tert-butylamino)-1,3,5-triazine-2,4-diol Not in list C7H12N4O2 Oc1nc(NC(C)(C)C)nc(O)n1 InChI=1S/C7H12N4O2/c1-7(2,3)11-4-8-5(12)10-6(13)9-4/h1-3H3,(H3,8,9,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance 6-(tert-butylamino)-1,3,5-triazine-2,4-diol 6-(tert-butylamino)-1,3,5-triazine-2,4-diol Not in list C7H12N4O2 Oc1nc(NC(C)(C)C)nc(O)n1 InChI=1S/C7H12N4O2/c1-7(2,3)11-4-8-5(12)10-6(13)9-4/h1-3H3,(H3,8,9,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance 6-(tert-butylamino)-1,3,5-triazine-2,4-diol 6-(tert-butylamino)-1,3,5-triazine-2,4-diol Not in list C7H12N4O2 Oc1nc(NC(C)(C)C)nc(O)n1 InChI=1S/C7H12N4O2/c1-7(2,3)11-4-8-5(12)10-6(13)9-4/h1-3H3,(H3,8,9,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance 6-(tert-butylamino)-1,3,5-triazine-2,4-diol 6-(tert-butylamino)-1,3,5-triazine-2,4-diol Not in list C7H12N4O2 Oc1nc(NC(C)(C)C)nc(O)n1 InChI=1S/C7H12N4O2/c1-7(2,3)11-4-8-5(12)10-6(13)9-4/h1-3H3,(H3,8,9,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes with Negative RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance 6-(tert-butylamino)-1,3,5-triazine-2,4-diol 6-(tert-butylamino)-1,3,5-triazine-2,4-diol Not in list C7H12N4O2 Oc1nc(NC(C)(C)C)nc(O)n1 InChI=1S/C7H12N4O2/c1-7(2,3)11-4-8-5(12)10-6(13)9-4/h1-3H3,(H3,8,9,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes without Negative RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance 6-(tert-butylamino)-1,3,5-triazine-2,4-diol 6-(tert-butylamino)-1,3,5-triazine-2,4-diol Not in list C7H12N4O2 Oc1nc(NC(C)(C)C)nc(O)n1 InChI=1S/C7H12N4O2/c1-7(2,3)11-4-8-5(12)10-6(13)9-4/h1-3H3,(H3,8,9,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance 6-(tert-butylamino)-1,3,5-triazine-2,4-diol 6-(tert-butylamino)-1,3,5-triazine-2,4-diol Not in list C7H12N4O2 Oc1nc(NC(C)(C)C)nc(O)n1 InChI=1S/C7H12N4O2/c1-7(2,3)11-4-8-5(12)10-6(13)9-4/h1-3H3,(H3,8,9,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance 6-(tert-butylamino)-1,3,5-triazine-2,4-diol 6-(tert-butylamino)-1,3,5-triazine-2,4-diol Not in list C7H12N4O2 Oc1nc(NC(C)(C)C)nc(O)n1 InChI=1S/C7H12N4O2/c1-7(2,3)11-4-8-5(12)10-6(13)9-4/h1-3H3,(H3,8,9,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance 6-(tert-butylamino)-1,3,5-triazine-2,4-diol 6-(tert-butylamino)-1,3,5-triazine-2,4-diol Not in list C7H12N4O2 Oc1nc(NC(C)(C)C)nc(O)n1 InChI=1S/C7H12N4O2/c1-7(2,3)11-4-8-5(12)10-6(13)9-4/h1-3H3,(H3,8,9,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes without Negative RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance 4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one 4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one 4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one C8H14N4O2 O=C1N=C(NC(C)(C)C)N=C(O)N1C InChI=1S/C8H14N4O2/c1-8(2,3)11-5-9-6(13)12(4)7(14)10-5/h1-4H3,(H2,9,10,11,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance 4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one 4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one 4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one C8H14N4O2 O=C1N=C(NC(C)(C)C)N=C(O)N1C InChI=1S/C8H14N4O2/c1-8(2,3)11-5-9-6(13)12(4)7(14)10-5/h1-4H3,(H2,9,10,11,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes without Negative RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance 4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one 4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one 4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one C8H14N4O2 O=C1N=C(NC(C)(C)C)N=C(O)N1C InChI=1S/C8H14N4O2/c1-8(2,3)11-5-9-6(13)12(4)7(14)10-5/h1-4H3,(H2,9,10,11,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes with Negative RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance 4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one 4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one 4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one C8H14N4O2 O=C1N=C(NC(C)(C)C)N=C(O)N1C InChI=1S/C8H14N4O2/c1-8(2,3)11-5-9-6(13)12(4)7(14)10-5/h1-4H3,(H2,9,10,11,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes without Negative RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance 4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one 4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one 4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one C8H14N4O2 O=C1N=C(NC(C)(C)C)N=C(O)N1C InChI=1S/C8H14N4O2/c1-8(2,3)11-5-9-6(13)12(4)7(14)10-5/h1-4H3,(H2,9,10,11,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance 4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one 4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one 4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one C8H14N4O2 O=C1N=C(NC(C)(C)C)N=C(O)N1C InChI=1S/C8H14N4O2/c1-8(2,3)11-5-9-6(13)12(4)7(14)10-5/h1-4H3,(H2,9,10,11,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance 4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one 4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one 4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one C8H14N4O2 O=C1N=C(NC(C)(C)C)N=C(O)N1C InChI=1S/C8H14N4O2/c1-8(2,3)11-5-9-6(13)12(4)7(14)10-5/h1-4H3,(H2,9,10,11,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance 4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one 4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one 4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one C8H14N4O2 O=C1N=C(NC(C)(C)C)N=C(O)N1C InChI=1S/C8H14N4O2/c1-8(2,3)11-5-9-6(13)12(4)7(14)10-5/h1-4H3,(H2,9,10,11,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance 4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one 4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one 4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one C8H14N4O2 O=C1N=C(NC(C)(C)C)N=C(O)N1C InChI=1S/C8H14N4O2/c1-8(2,3)11-5-9-6(13)12(4)7(14)10-5/h1-4H3,(H2,9,10,11,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance 4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one 4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one 4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one C8H14N4O2 O=C1N=C(NC(C)(C)C)N=C(O)N1C InChI=1S/C8H14N4O2/c1-8(2,3)11-5-9-6(13)12(4)7(14)10-5/h1-4H3,(H2,9,10,11,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance 4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one 4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one 4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one C8H14N4O2 O=C1N=C(NC(C)(C)C)N=C(O)N1C InChI=1S/C8H14N4O2/c1-8(2,3)11-5-9-6(13)12(4)7(14)10-5/h1-4H3,(H2,9,10,11,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance 4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one 4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one 4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one C8H14N4O2 O=C1N=C(NC(C)(C)C)N=C(O)N1C InChI=1S/C8H14N4O2/c1-8(2,3)11-5-9-6(13)12(4)7(14)10-5/h1-4H3,(H2,9,10,11,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes with Negative RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance 4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one 4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one 4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one C8H14N4O2 O=C1N=C(NC(C)(C)C)N=C(O)N1C InChI=1S/C8H14N4O2/c1-8(2,3)11-5-9-6(13)12(4)7(14)10-5/h1-4H3,(H2,9,10,11,13,14) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Positive large colonies RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance 4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one 4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one 4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one C8H14N4O2 O=C1N=C(NC(C)(C)C)N=C(O)N1C InChI=1S/C8H14N4O2/c1-8(2,3)11-5-9-6(13)12(4)7(14)10-5/h1-4H3,(H2,9,10,11,13,14) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative large colonies RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance 4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one 4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one 4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one C8H14N4O2 O=C1N=C(NC(C)(C)C)N=C(O)N1C InChI=1S/C8H14N4O2/c1-8(2,3)11-5-9-6(13)12(4)7(14)10-5/h1-4H3,(H2,9,10,11,13,14) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Positive small colonies RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance 4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one 4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one 4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one C8H14N4O2 O=C1N=C(NC(C)(C)C)N=C(O)N1C InChI=1S/C8H14N4O2/c1-8(2,3)11-5-9-6(13)12(4)7(14)10-5/h1-4H3,(H2,9,10,11,13,14) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative small colonies RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance 4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one 4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one 4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one C8H14N4O2 O=C1N=C(NC(C)(C)C)N=C(O)N1C InChI=1S/C8H14N4O2/c1-8(2,3)11-5-9-6(13)12(4)7(14)10-5/h1-4H3,(H2,9,10,11,13,14) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance 4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one 4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one 4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one C8H14N4O2 O=C1N=C(NC(C)(C)C)N=C(O)N1C InChI=1S/C8H14N4O2/c1-8(2,3)11-5-9-6(13)12(4)7(14)10-5/h1-4H3,(H2,9,10,11,13,14) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance 4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one 4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one 4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one C8H14N4O2 O=C1N=C(NC(C)(C)C)N=C(O)N1C InChI=1S/C8H14N4O2/c1-8(2,3)11-5-9-6(13)12(4)7(14)10-5/h1-4H3,(H2,9,10,11,13,14) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 Male oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Terbuthylazine 227-637-9 5915-41-3 single chemical entity Component is a metabolite of the substance 4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one 4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one 4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one C8H14N4O2 O=C1N=C(NC(C)(C)C)N=C(O)N1C InChI=1S/C8H14N4O2/c1-8(2,3)11-5-9-6(13)12(4)7(14)10-5/h1-4H3,(H2,9,10,11,13,14) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 Male oral: unspecified 48.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Terbuthylazine (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine 10Jan2011 2011 doi:10.2903/j.efsa.2011.1969
+Lenacil 218-499-0 2164-08-1 single chemical entity Component is identical to the substance Lenacil 218-499-0 2164-08-1 3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione Lenacil C13H18N2O2 O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3 InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data no data Negative RMS: Belgium Lenacil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil 07Oct2009 2009 doi:10.2903/j.efsa.2009.1326
+Lenacil 218-499-0 2164-08-1 single chemical entity Component is identical to the substance Lenacil 218-499-0 2164-08-1 3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione Lenacil C13H18N2O2 O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3 InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported no data no data Negative RMS: Belgium Lenacil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil 07Oct2009 2009 doi:10.2903/j.efsa.2009.1326
+Lenacil 218-499-0 2164-08-1 single chemical entity Component is identical to the substance Lenacil 218-499-0 2164-08-1 3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione Lenacil C13H18N2O2 O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3 InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data no data Negative RMS: Belgium Lenacil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil 07Oct2009 2009 doi:10.2903/j.efsa.2009.1326
+Lenacil 218-499-0 2164-08-1 single chemical entity Component is identical to the substance Lenacil 218-499-0 2164-08-1 3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione Lenacil C13H18N2O2 O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3 InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 97 Not reported no data no data Negative RMS: Belgium Lenacil 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil 07Oct2009 2009 doi:10.2903/j.efsa.2009.1326
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other DNA damage and/or repair SOS/umu test in vitro No guideline available Not reported Not applicable Acceptable Salmonella typhimurium (as organism) Not reported no data no data Negative RMS: Finland Malathion (Addendum 1) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Finland Malathion (Addendum 1) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported no data without Negative RMS: Finland Malathion (Addendum 1) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported no data with Negative RMS: Finland Malathion (Addendum 1) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Finland Malathion (Addendum 1) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Finland Malathion (Addendum 1) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Finland Malathion (Addendum 1) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro No guideline followed Not reported Not applicable Acceptable Other Not reported no data no data Positive RMS: Finland Malathion (Addendum 1) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No data Acceptable Human (as organism) lymphocytes Not reported no data no data Positive RMS: Finland Malathion (Addendum 1) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is a metabolite of the substance Diethyl (2RS)-2-[(dimethoxyphosphoryl)sulfanyl]butanedioate 1634-78-2 Diethyl 2-dimethoxyphosphorylsulfanylbutanedioate Malaoxon C10H19O7PS CCOC(=O)CC(C(=O)OCC)SP(=O)(OC)OC InChI=1S/C10H19O7PS/c1-5-16-9(11)7-8(10(12)17-6-2)19-18(13,14-3)15-4/h8H,5-7H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vitro No guideline available Not reported Not applicable Acceptable Human (as organism) lymphocytes Not reported no data no data Positive RMS: Finland Malathion (Addendum 1) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is a metabolite of the substance Diethyl (2RS)-2-[(dimethoxyphosphoryl)sulfanyl]butanedioate 1634-78-2 Diethyl 2-dimethoxyphosphorylsulfanylbutanedioate Malaoxon C10H19O7PS CCOC(=O)CC(C(=O)OCC)SP(=O)(OC)OC InChI=1S/C10H19O7PS/c1-5-16-9(11)7-8(10(12)17-6-2)19-18(13,14-3)15-4/h8H,5-7H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vitro No guideline available Not reported Not applicable Acceptable Human (as organism) lymphocytes Not reported no data no data Positive RMS: Finland Malathion (Addendum 1) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) Swiss Male/Female intraperitoneal 24.0000000000 h yes not applicable Positive RMS: Finland Malathion (Addendum 1) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No data Acceptable House mouse (as animal) Swiss Male/Female intraperitoneal 48.0000000000 h yes, concurrent no treatment not applicable Positive RMS: Finland Malathion (Addendum 1) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No data Acceptable House mouse (as animal) Swiss Male/Female intraperitoneal 24.0000000000 h yes, concurrent no treatment not applicable Positive RMS: Finland Malathion (Addendum 1) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No data Acceptable House mouse (as animal) Not reported No data intraperitoneal no data not applicable Positive RMS: Finland Malathion (Addendum 1) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other chromosome aberration other in vitro No guideline available Not reported Not applicable Acceptable Saccharomyces cerevisiae (as organism) Not reported Not reported no data no data Negative RMS: Finland Malathion (Addendum 1) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is identical to the substance Malathion 204-497-7 121-75-5 diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate Malathion C10H19O6PS2 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3 organic compound Other Other other in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) No data Not reported no data not applicable Positive RMS: Finland Malathion (Addendum 1) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is a metabolite of the substance (2RS)- 2-[(dimethoxyphosphorothioyl)sulfanyl]-4-ethoxy-4-oxobutanoic acid 1190-29-0 2-Dimethoxyphosphinothioylsulfanyl-4-ethoxy-4-oxobutanoic acid Not in list C8H15O6PS2 CCOC(=O)CC(C(=O)O)SP(=S)(OC)OC InChI=1S/C8H15O6PS2/c1-4-14-7(9)5-6(8(10)11)17-15(16,12-2)13-3/h6H,4-5H2,1-3H3,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Finland Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is a metabolite of the substance (2RS)- 2-[(dimethoxyphosphorothioyl)sulfanyl]-4-ethoxy-4-oxobutanoic acid 1190-29-0 2-Dimethoxyphosphinothioylsulfanyl-4-ethoxy-4-oxobutanoic acid Not in list C8H15O6PS2 CCOC(=O)CC(C(=O)O)SP(=S)(OC)OC InChI=1S/C8H15O6PS2/c1-4-14-7(9)5-6(8(10)11)17-15(16,12-2)13-3/h6H,4-5H2,1-3H3,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Finland Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is a metabolite of the substance (2RS)- 2-[(dimethoxyphosphorothioyl)sulfanyl]-4-ethoxy-4-oxobutanoic acid 1190-29-0 2-Dimethoxyphosphinothioylsulfanyl-4-ethoxy-4-oxobutanoic acid Not in list C8H15O6PS2 CCOC(=O)CC(C(=O)O)SP(=S)(OC)OC InChI=1S/C8H15O6PS2/c1-4-14-7(9)5-6(8(10)11)17-15(16,12-2)13-3/h6H,4-5H2,1-3H3,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Finland Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is a metabolite of the substance (2RS)- 2-[(dimethoxyphosphorothioyl)sulfanyl]-4-ethoxy-4-oxobutanoic acid 1190-29-0 2-Dimethoxyphosphinothioylsulfanyl-4-ethoxy-4-oxobutanoic acid Not in list C8H15O6PS2 CCOC(=O)CC(C(=O)O)SP(=S)(OC)OC InChI=1S/C8H15O6PS2/c1-4-14-7(9)5-6(8(10)11)17-15(16,12-2)13-3/h6H,4-5H2,1-3H3,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Finland Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is a metabolite of the substance (2RS)- 2-[(dimethoxyphosphorothioyl)sulfanyl]-4-ethoxy-4-oxobutanoic acid 1190-29-0 2-Dimethoxyphosphinothioylsulfanyl-4-ethoxy-4-oxobutanoic acid Not in list C8H15O6PS2 CCOC(=O)CC(C(=O)O)SP(=S)(OC)OC InChI=1S/C8H15O6PS2/c1-4-14-7(9)5-6(8(10)11)17-15(16,12-2)13-3/h6H,4-5H2,1-3H3,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Finland Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is a metabolite of the substance (2RS)- 2-[(dimethoxyphosphorothioyl)sulfanyl]-4-ethoxy-4-oxobutanoic acid 1190-29-0 2-Dimethoxyphosphinothioylsulfanyl-4-ethoxy-4-oxobutanoic acid Not in list C8H15O6PS2 CCOC(=O)CC(C(=O)O)SP(=S)(OC)OC InChI=1S/C8H15O6PS2/c1-4-14-7(9)5-6(8(10)11)17-15(16,12-2)13-3/h6H,4-5H2,1-3H3,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Finland Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is a metabolite of the substance (2RS)- 2-[(dimethoxyphosphorothioyl)sulfanyl]-4-ethoxy-4-oxobutanoic acid 1190-29-0 2-Dimethoxyphosphinothioylsulfanyl-4-ethoxy-4-oxobutanoic acid Not in list C8H15O6PS2 CCOC(=O)CC(C(=O)O)SP(=S)(OC)OC InChI=1S/C8H15O6PS2/c1-4-14-7(9)5-6(8(10)11)17-15(16,12-2)13-3/h6H,4-5H2,1-3H3,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Finland Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is a metabolite of the substance (2RS)- 2-[(dimethoxyphosphorothioyl)sulfanyl]-4-ethoxy-4-oxobutanoic acid 1190-29-0 2-Dimethoxyphosphinothioylsulfanyl-4-ethoxy-4-oxobutanoic acid Not in list C8H15O6PS2 CCOC(=O)CC(C(=O)O)SP(=S)(OC)OC InChI=1S/C8H15O6PS2/c1-4-14-7(9)5-6(8(10)11)17-15(16,12-2)13-3/h6H,4-5H2,1-3H3,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Finland Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is a metabolite of the substance (2RS)- 2-[(dimethoxyphosphorothioyl)sulfanyl]-4-ethoxy-4-oxobutanoic acid 1190-29-0 2-Dimethoxyphosphinothioylsulfanyl-4-ethoxy-4-oxobutanoic acid Not in list C8H15O6PS2 CCOC(=O)CC(C(=O)O)SP(=S)(OC)OC InChI=1S/C8H15O6PS2/c1-4-14-7(9)5-6(8(10)11)17-15(16,12-2)13-3/h6H,4-5H2,1-3H3,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Finland Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is a metabolite of the substance (2RS)- 2-[(dimethoxyphosphorothioyl)sulfanyl]-4-ethoxy-4-oxobutanoic acid 1190-29-0 2-Dimethoxyphosphinothioylsulfanyl-4-ethoxy-4-oxobutanoic acid Not in list C8H15O6PS2 CCOC(=O)CC(C(=O)O)SP(=S)(OC)OC InChI=1S/C8H15O6PS2/c1-4-14-7(9)5-6(8(10)11)17-15(16,12-2)13-3/h6H,4-5H2,1-3H3,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Finland Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is a metabolite of the substance (2RS)- 2-[(dimethoxyphosphorothioyl)sulfanyl]butanedioic acid 2-dimethoxyphosphinothioylsulfanylbutanedioic acid Not in list C6H11O6PS2 COP(=S)(OC)SC(CC(=O)O)C(=O)O InChI=1S/C6H11O6PS2/c1-11-13(14,12-2)15-4(6(9)10)3-5(7)8/h4H,3H2,1-2H3,(H,7,8)(H,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Finland Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is a metabolite of the substance (2RS)- 2-[(dimethoxyphosphorothioyl)sulfanyl]butanedioic acid 2-dimethoxyphosphinothioylsulfanylbutanedioic acid Not in list C6H11O6PS2 COP(=S)(OC)SC(CC(=O)O)C(=O)O InChI=1S/C6H11O6PS2/c1-11-13(14,12-2)15-4(6(9)10)3-5(7)8/h4H,3H2,1-2H3,(H,7,8)(H,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Finland Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is a metabolite of the substance (2RS)- 2-[(dimethoxyphosphorothioyl)sulfanyl]butanedioic acid 2-dimethoxyphosphinothioylsulfanylbutanedioic acid Not in list C6H11O6PS2 COP(=S)(OC)SC(CC(=O)O)C(=O)O InChI=1S/C6H11O6PS2/c1-11-13(14,12-2)15-4(6(9)10)3-5(7)8/h4H,3H2,1-2H3,(H,7,8)(H,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Finland Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is a metabolite of the substance (2RS)- 2-[(dimethoxyphosphorothioyl)sulfanyl]butanedioic acid 2-dimethoxyphosphinothioylsulfanylbutanedioic acid Not in list C6H11O6PS2 COP(=S)(OC)SC(CC(=O)O)C(=O)O InChI=1S/C6H11O6PS2/c1-11-13(14,12-2)15-4(6(9)10)3-5(7)8/h4H,3H2,1-2H3,(H,7,8)(H,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Finland Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is a metabolite of the substance (2RS)- 2-[(dimethoxyphosphorothioyl)sulfanyl]butanedioic acid 2-dimethoxyphosphinothioylsulfanylbutanedioic acid Not in list C6H11O6PS2 COP(=S)(OC)SC(CC(=O)O)C(=O)O InChI=1S/C6H11O6PS2/c1-11-13(14,12-2)15-4(6(9)10)3-5(7)8/h4H,3H2,1-2H3,(H,7,8)(H,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Finland Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is a metabolite of the substance (2RS)- 2-[(dimethoxyphosphorothioyl)sulfanyl]butanedioic acid 2-dimethoxyphosphinothioylsulfanylbutanedioic acid Not in list C6H11O6PS2 COP(=S)(OC)SC(CC(=O)O)C(=O)O InChI=1S/C6H11O6PS2/c1-11-13(14,12-2)15-4(6(9)10)3-5(7)8/h4H,3H2,1-2H3,(H,7,8)(H,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Finland Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is a metabolite of the substance (2RS)- 2-[(dimethoxyphosphorothioyl)sulfanyl]butanedioic acid 2-dimethoxyphosphinothioylsulfanylbutanedioic acid Not in list C6H11O6PS2 COP(=S)(OC)SC(CC(=O)O)C(=O)O InChI=1S/C6H11O6PS2/c1-11-13(14,12-2)15-4(6(9)10)3-5(7)8/h4H,3H2,1-2H3,(H,7,8)(H,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Finland Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is a metabolite of the substance (2RS)- 2-[(dimethoxyphosphorothioyl)sulfanyl]butanedioic acid 2-dimethoxyphosphinothioylsulfanylbutanedioic acid Not in list C6H11O6PS2 COP(=S)(OC)SC(CC(=O)O)C(=O)O InChI=1S/C6H11O6PS2/c1-11-13(14,12-2)15-4(6(9)10)3-5(7)8/h4H,3H2,1-2H3,(H,7,8)(H,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Finland Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is a metabolite of the substance (2RS)- 2-[(dimethoxyphosphorothioyl)sulfanyl]butanedioic acid 2-dimethoxyphosphinothioylsulfanylbutanedioic acid Not in list C6H11O6PS2 COP(=S)(OC)SC(CC(=O)O)C(=O)O InChI=1S/C6H11O6PS2/c1-11-13(14,12-2)15-4(6(9)10)3-5(7)8/h4H,3H2,1-2H3,(H,7,8)(H,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Finland Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is a metabolite of the substance (2RS)- 2-[(dimethoxyphosphorothioyl)sulfanyl]butanedioic acid 2-dimethoxyphosphinothioylsulfanylbutanedioic acid Not in list C6H11O6PS2 COP(=S)(OC)SC(CC(=O)O)C(=O)O InChI=1S/C6H11O6PS2/c1-11-13(14,12-2)15-4(6(9)10)3-5(7)8/h4H,3H2,1-2H3,(H,7,8)(H,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Finland Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is a metabolite of the substance Diethyl (2RS)-2-{[hydroxy(methoxy)phosphorothioyl]sulfanyl}butanedioate diethyl 2-{[hydroxy(methoxy)phosphorothioyl]sulfanyl}butanedioate Not in list C9H17O6PS2 CCOC(=O)CC(SP(=S)(O)OC)C(=O)OCC InChI=1S/C9H17O6PS2/c1-4-14-8(10)6-7(9(11)15-5-2)18-16(12,17)13-3/h7H,4-6H2,1-3H3,(H,12,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Finland Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is a metabolite of the substance Diethyl (2RS)-2-{[hydroxy(methoxy)phosphorothioyl]sulfanyl}butanedioate diethyl 2-{[hydroxy(methoxy)phosphorothioyl]sulfanyl}butanedioate Not in list C9H17O6PS2 CCOC(=O)CC(SP(=S)(O)OC)C(=O)OCC InChI=1S/C9H17O6PS2/c1-4-14-8(10)6-7(9(11)15-5-2)18-16(12,17)13-3/h7H,4-6H2,1-3H3,(H,12,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Finland Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is a metabolite of the substance Diethyl (2RS)-2-{[hydroxy(methoxy)phosphorothioyl]sulfanyl}butanedioate diethyl 2-{[hydroxy(methoxy)phosphorothioyl]sulfanyl}butanedioate Not in list C9H17O6PS2 CCOC(=O)CC(SP(=S)(O)OC)C(=O)OCC InChI=1S/C9H17O6PS2/c1-4-14-8(10)6-7(9(11)15-5-2)18-16(12,17)13-3/h7H,4-6H2,1-3H3,(H,12,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Finland Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is a metabolite of the substance Diethyl (2RS)-2-{[hydroxy(methoxy)phosphorothioyl]sulfanyl}butanedioate diethyl 2-{[hydroxy(methoxy)phosphorothioyl]sulfanyl}butanedioate Not in list C9H17O6PS2 CCOC(=O)CC(SP(=S)(O)OC)C(=O)OCC InChI=1S/C9H17O6PS2/c1-4-14-8(10)6-7(9(11)15-5-2)18-16(12,17)13-3/h7H,4-6H2,1-3H3,(H,12,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Finland Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is a metabolite of the substance Diethyl (2RS)-2-{[hydroxy(methoxy)phosphorothioyl]sulfanyl}butanedioate diethyl 2-{[hydroxy(methoxy)phosphorothioyl]sulfanyl}butanedioate Not in list C9H17O6PS2 CCOC(=O)CC(SP(=S)(O)OC)C(=O)OCC InChI=1S/C9H17O6PS2/c1-4-14-8(10)6-7(9(11)15-5-2)18-16(12,17)13-3/h7H,4-6H2,1-3H3,(H,12,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Finland Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is a metabolite of the substance Diethyl (2RS)-2-{[hydroxy(methoxy)phosphorothioyl]sulfanyl}butanedioate diethyl 2-{[hydroxy(methoxy)phosphorothioyl]sulfanyl}butanedioate Not in list C9H17O6PS2 CCOC(=O)CC(SP(=S)(O)OC)C(=O)OCC InChI=1S/C9H17O6PS2/c1-4-14-8(10)6-7(9(11)15-5-2)18-16(12,17)13-3/h7H,4-6H2,1-3H3,(H,12,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Finland Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is a metabolite of the substance Diethyl (2RS)-2-{[hydroxy(methoxy)phosphorothioyl]sulfanyl}butanedioate diethyl 2-{[hydroxy(methoxy)phosphorothioyl]sulfanyl}butanedioate Not in list C9H17O6PS2 CCOC(=O)CC(SP(=S)(O)OC)C(=O)OCC InChI=1S/C9H17O6PS2/c1-4-14-8(10)6-7(9(11)15-5-2)18-16(12,17)13-3/h7H,4-6H2,1-3H3,(H,12,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Finland Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is a metabolite of the substance Diethyl (2RS)-2-{[hydroxy(methoxy)phosphorothioyl]sulfanyl}butanedioate diethyl 2-{[hydroxy(methoxy)phosphorothioyl]sulfanyl}butanedioate Not in list C9H17O6PS2 CCOC(=O)CC(SP(=S)(O)OC)C(=O)OCC InChI=1S/C9H17O6PS2/c1-4-14-8(10)6-7(9(11)15-5-2)18-16(12,17)13-3/h7H,4-6H2,1-3H3,(H,12,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Finland Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is a metabolite of the substance Diethyl (2RS)-2-{[hydroxy(methoxy)phosphorothioyl]sulfanyl}butanedioate diethyl 2-{[hydroxy(methoxy)phosphorothioyl]sulfanyl}butanedioate Not in list C9H17O6PS2 CCOC(=O)CC(SP(=S)(O)OC)C(=O)OCC InChI=1S/C9H17O6PS2/c1-4-14-8(10)6-7(9(11)15-5-2)18-16(12,17)13-3/h7H,4-6H2,1-3H3,(H,12,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Finland Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Malathion 204-497-7 121-75-5 single chemical entity Component is a metabolite of the substance Diethyl (2RS)-2-{[hydroxy(methoxy)phosphorothioyl]sulfanyl}butanedioate diethyl 2-{[hydroxy(methoxy)phosphorothioyl]sulfanyl}butanedioate Not in list C9H17O6PS2 CCOC(=O)CC(SP(=S)(O)OC)C(=O)OCC InChI=1S/C9H17O6PS2/c1-4-14-8(10)6-7(9(11)15-5-2)18-16(12,17)13-3/h7H,4-6H2,1-3H3,(H,12,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Finland Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment) 2009 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance malathion 28Jul2009 2009 doi:10.2903/j.efsa.2009.333r
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is identical to the substance Metalaxyl-M 615-135-6 70630-17-0 methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate Metalaxyl-M C15H21NO4 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No data Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Positive RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is identical to the substance Metalaxyl-M 615-135-6 70630-17-0 methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate Metalaxyl-M C15H21NO4 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No data Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Positive RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is identical to the substance Metalaxyl-M 615-135-6 70630-17-0 methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate Metalaxyl-M C15H21NO4 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian cell micronucleus test in vitro Equivalent or similar to OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test) No data Acceptable Human (as organism) lymphocytes Not reported yes without Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is identical to the substance Metalaxyl-M 615-135-6 70630-17-0 methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate Metalaxyl-M C15H21NO4 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No data Acceptable Human (as organism) lymphocytes Not reported yes without Ambiguous RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is identical to the substance Metalaxyl-M 615-135-6 70630-17-0 methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate Metalaxyl-M C15H21NO4 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable Rat (as animal) Wistar Male oral: unspecified 24.0000000000 h yes not applicable Negative no evidence RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2,6-dimethylaniline 201-758-7 87-62-7 2,6-dimethylaniline Not in list C8H11N CC1=C(C(=CC=C1)C)N InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2,6-dimethylaniline 201-758-7 87-62-7 2,6-dimethylaniline Not in list C8H11N CC1=C(C(=CC=C1)C)N InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2,6-dimethylaniline 201-758-7 87-62-7 2,6-dimethylaniline Not in list C8H11N CC1=C(C(=CC=C1)C)N InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2,6-dimethylaniline 201-758-7 87-62-7 2,6-dimethylaniline Not in list C8H11N CC1=C(C(=CC=C1)C)N InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2,6-dimethylaniline 201-758-7 87-62-7 2,6-dimethylaniline Not in list C8H11N CC1=C(C(=CC=C1)C)N InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2,6-dimethylaniline 201-758-7 87-62-7 2,6-dimethylaniline Not in list C8H11N CC1=C(C(=CC=C1)C)N InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2,6-dimethylaniline 201-758-7 87-62-7 2,6-dimethylaniline Not in list C8H11N CC1=C(C(=CC=C1)C)N InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2,6-dimethylaniline 201-758-7 87-62-7 2,6-dimethylaniline Not in list C8H11N CC1=C(C(=CC=C1)C)N InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2,6-dimethylaniline 201-758-7 87-62-7 2,6-dimethylaniline Not in list C8H11N CC1=C(C(=CC=C1)C)N InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2,6-dimethylaniline 201-758-7 87-62-7 2,6-dimethylaniline Not in list C8H11N CC1=C(C(=CC=C1)C)N InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2,6-dimethylaniline 201-758-7 87-62-7 2,6-dimethylaniline Not in list C8H11N CC1=C(C(=CC=C1)C)N InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2,6-dimethylaniline 201-758-7 87-62-7 2,6-dimethylaniline Not in list C8H11N CC1=C(C(=CC=C1)C)N InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2,6-dimethylaniline 201-758-7 87-62-7 2,6-dimethylaniline Not in list C8H11N CC1=C(C(=CC=C1)C)N InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2,6-dimethylaniline 201-758-7 87-62-7 2,6-dimethylaniline Not in list C8H11N CC1=C(C(=CC=C1)C)N InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2,6-dimethylaniline 201-758-7 87-62-7 2,6-dimethylaniline Not in list C8H11N CC1=C(C(=CC=C1)C)N InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2,6-dimethylaniline 201-758-7 87-62-7 2,6-dimethylaniline Not in list C8H11N CC1=C(C(=CC=C1)C)N InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2,6-dimethylaniline 201-758-7 87-62-7 2,6-dimethylaniline Not in list C8H11N CC1=C(C(=CC=C1)C)N InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2,6-dimethylaniline 201-758-7 87-62-7 2,6-dimethylaniline Not in list C8H11N CC1=C(C(=CC=C1)C)N InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2,6-dimethylaniline 201-758-7 87-62-7 2,6-dimethylaniline Not in list C8H11N CC1=C(C(=CC=C1)C)N InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2,6-dimethylaniline 201-758-7 87-62-7 2,6-dimethylaniline Not in list C8H11N CC1=C(C(=CC=C1)C)N InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No data Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data without Positive no information RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2,6-dimethylaniline 201-758-7 87-62-7 2,6-dimethylaniline Not in list C8H11N CC1=C(C(=CC=C1)C)N InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No data Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data with Positive no information RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2,6-dimethylaniline 201-758-7 87-62-7 2,6-dimethylaniline Not in list C8H11N CC1=C(C(=CC=C1)C)N InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No data Acceptable Hamster (as animal) CHO Not reported no data without Positive RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2,6-dimethylaniline 201-758-7 87-62-7 2,6-dimethylaniline Not in list C8H11N CC1=C(C(=CC=C1)C)N InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No data Acceptable Hamster (as animal) CHO Not reported no data with Positive RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2,6-dimethylaniline 201-758-7 87-62-7 2,6-dimethylaniline Not in list C8H11N CC1=C(C(=CC=C1)C)N InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No data Acceptable Hamster (as animal) CHO Not reported no data without Positive RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2,6-dimethylaniline 201-758-7 87-62-7 2,6-dimethylaniline Not in list C8H11N CC1=C(C(=CC=C1)C)N InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No data Acceptable Hamster (as animal) CHO Not reported no data with Positive RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2,6-dimethylaniline 201-758-7 87-62-7 2,6-dimethylaniline Not in list C8H11N CC1=C(C(=CC=C1)C)N InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable House mouse (as animal) Not reported No data oral: unspecified no data not applicable Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2,6-dimethylaniline 201-758-7 87-62-7 2,6-dimethylaniline Not in list C8H11N CC1=C(C(=CC=C1)C)N InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No data Acceptable House mouse (as animal) Not reported No data oral: unspecified no data not applicable Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2,6-dimethylaniline 201-758-7 87-62-7 2,6-dimethylaniline Not in list C8H11N CC1=C(C(=CC=C1)C)N InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable Rat (as animal) Not reported No data intraperitoneal no data not applicable Positive RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2,6-dimethylaniline 201-758-7 87-62-7 2,6-dimethylaniline Not in list C8H11N CC1=C(C(=CC=C1)C)N InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) Other Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2,6-dimethylaniline 201-758-7 87-62-7 2,6-dimethylaniline Not in list C8H11N CC1=C(C(=CC=C1)C)N InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) Other Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2,6-dimethylaniline 201-758-7 87-62-7 2,6-dimethylaniline Not in list C8H11N CC1=C(C(=CC=C1)C)N InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) Other Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2,6-dimethylaniline 201-758-7 87-62-7 2,6-dimethylaniline Not in list C8H11N CC1=C(C(=CC=C1)C)N InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) Other Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2,6-dimethylaniline 201-758-7 87-62-7 2,6-dimethylaniline Not in list C8H11N CC1=C(C(=CC=C1)C)N InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2,6-dimethylaniline 201-758-7 87-62-7 2,6-dimethylaniline Not in list C8H11N CC1=C(C(=CC=C1)C)N InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2,6-dimethylaniline 201-758-7 87-62-7 2,6-dimethylaniline Not in list C8H11N CC1=C(C(=CC=C1)C)N InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2,6-dimethylaniline 201-758-7 87-62-7 2,6-dimethylaniline Not in list C8H11N CC1=C(C(=CC=C1)C)N InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2,6-dimethylaniline 201-758-7 87-62-7 2,6-dimethylaniline Not in list C8H11N CC1=C(C(=CC=C1)C)N InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2,6-dimethylaniline 201-758-7 87-62-7 2,6-dimethylaniline Not in list C8H11N CC1=C(C(=CC=C1)C)N InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2,6-dimethylaniline 201-758-7 87-62-7 2,6-dimethylaniline Not in list C8H11N CC1=C(C(=CC=C1)C)N InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2,6-dimethylaniline 201-758-7 87-62-7 2,6-dimethylaniline Not in list C8H11N CC1=C(C(=CC=C1)C)N InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2,6-dimethylaniline 201-758-7 87-62-7 2,6-dimethylaniline Not in list C8H11N CC1=C(C(=CC=C1)C)N InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2,6-dimethylaniline 201-758-7 87-62-7 2,6-dimethylaniline Not in list C8H11N CC1=C(C(=CC=C1)C)N InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2,6-dimethylaniline 201-758-7 87-62-7 2,6-dimethylaniline Not in list C8H11N CC1=C(C(=CC=C1)C)N InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2,6-dimethylaniline 201-758-7 87-62-7 2,6-dimethylaniline Not in list C8H11N CC1=C(C(=CC=C1)C)N InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2,6-dimethylaniline 201-758-7 87-62-7 2,6-dimethylaniline Not in list C8H11N CC1=C(C(=CC=C1)C)N InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance 2,6-dimethylaniline 201-758-7 87-62-7 2,6-dimethylaniline Not in list C8H11N CC1=C(C(=CC=C1)C)N InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metobromuron 221-301-5 3060-89-7 single chemical entity Component is a metabolite of the substance 1-(4-bromophenyl)-3-methylurea 1-(4-bromophenyl)-3-methylurea Not in list C8H9BrN2O Brc1ccc(NC(=O)NC)cc1 InChI=1/C8H9BrN2O/c1-10-8(12)11-7-4-2-6(9)3-5-7/h2-5H,1H3,(H2,10,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Metobromuron 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron. 04Feb2014 2014 doi:10.2903/j.efsa.2014.3541
+Metobromuron 221-301-5 3060-89-7 single chemical entity Component is a metabolite of the substance 1-(4-bromophenyl)-3-methylurea 1-(4-bromophenyl)-3-methylurea Not in list C8H9BrN2O Brc1ccc(NC(=O)NC)cc1 InChI=1/C8H9BrN2O/c1-10-8(12)11-7-4-2-6(9)3-5-7/h2-5H,1H3,(H2,10,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Metobromuron 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron. 04Feb2014 2014 doi:10.2903/j.efsa.2014.3541
+Metobromuron 221-301-5 3060-89-7 single chemical entity Component is a metabolite of the substance 1-(4-bromophenyl)-3-methylurea 1-(4-bromophenyl)-3-methylurea Not in list C8H9BrN2O Brc1ccc(NC(=O)NC)cc1 InChI=1/C8H9BrN2O/c1-10-8(12)11-7-4-2-6(9)3-5-7/h2-5H,1H3,(H2,10,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Metobromuron 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron. 04Feb2014 2014 doi:10.2903/j.efsa.2014.3541
+Metobromuron 221-301-5 3060-89-7 single chemical entity Component is a metabolite of the substance 1-(4-bromophenyl)-3-methylurea 1-(4-bromophenyl)-3-methylurea Not in list C8H9BrN2O Brc1ccc(NC(=O)NC)cc1 InChI=1/C8H9BrN2O/c1-10-8(12)11-7-4-2-6(9)3-5-7/h2-5H,1H3,(H2,10,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Metobromuron 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron. 04Feb2014 2014 doi:10.2903/j.efsa.2014.3541
+Metobromuron 221-301-5 3060-89-7 single chemical entity Component is a metabolite of the substance 1-(4-bromophenyl)-3-methylurea 1-(4-bromophenyl)-3-methylurea Not in list C8H9BrN2O Brc1ccc(NC(=O)NC)cc1 InChI=1/C8H9BrN2O/c1-10-8(12)11-7-4-2-6(9)3-5-7/h2-5H,1H3,(H2,10,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: France Metobromuron 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron. 04Feb2014 2014 doi:10.2903/j.efsa.2014.3541
+Metobromuron 221-301-5 3060-89-7 single chemical entity Component is a metabolite of the substance 1-(4-bromophenyl)-3-methylurea 1-(4-bromophenyl)-3-methylurea Not in list C8H9BrN2O Brc1ccc(NC(=O)NC)cc1 InChI=1/C8H9BrN2O/c1-10-8(12)11-7-4-2-6(9)3-5-7/h2-5H,1H3,(H2,10,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Metobromuron 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron. 04Feb2014 2014 doi:10.2903/j.efsa.2014.3541
+Metobromuron 221-301-5 3060-89-7 single chemical entity Component is a metabolite of the substance 1-(4-bromophenyl)-3-methylurea 1-(4-bromophenyl)-3-methylurea Not in list C8H9BrN2O Brc1ccc(NC(=O)NC)cc1 InChI=1/C8H9BrN2O/c1-10-8(12)11-7-4-2-6(9)3-5-7/h2-5H,1H3,(H2,10,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Metobromuron 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron. 04Feb2014 2014 doi:10.2903/j.efsa.2014.3541
+Metobromuron 221-301-5 3060-89-7 single chemical entity Component is a metabolite of the substance 1-(4-bromophenyl)-3-methylurea 1-(4-bromophenyl)-3-methylurea Not in list C8H9BrN2O Brc1ccc(NC(=O)NC)cc1 InChI=1/C8H9BrN2O/c1-10-8(12)11-7-4-2-6(9)3-5-7/h2-5H,1H3,(H2,10,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Metobromuron 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron. 04Feb2014 2014 doi:10.2903/j.efsa.2014.3541
+Metobromuron 221-301-5 3060-89-7 single chemical entity Component is a metabolite of the substance 1-(4-bromophenyl)-3-methylurea 1-(4-bromophenyl)-3-methylurea Not in list C8H9BrN2O Brc1ccc(NC(=O)NC)cc1 InChI=1/C8H9BrN2O/c1-10-8(12)11-7-4-2-6(9)3-5-7/h2-5H,1H3,(H2,10,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Metobromuron 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron. 04Feb2014 2014 doi:10.2903/j.efsa.2014.3541
+Metobromuron 221-301-5 3060-89-7 single chemical entity Component is a metabolite of the substance 1-(4-bromophenyl)-3-methylurea 1-(4-bromophenyl)-3-methylurea Not in list C8H9BrN2O Brc1ccc(NC(=O)NC)cc1 InChI=1/C8H9BrN2O/c1-10-8(12)11-7-4-2-6(9)3-5-7/h2-5H,1H3,(H2,10,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: France Metobromuron 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron. 04Feb2014 2014 doi:10.2903/j.efsa.2014.3541
+Metobromuron 221-301-5 3060-89-7 single chemical entity Component is a metabolite of the substance 1-(4-bromophenyl)urea 1-(4-bromophenyl)urea Not in list C7H7BrN2O Brc1ccc(NC(N)=O)cc1 InChI=1/C7H7BrN2O/c8-5-1-3-6(4-2-5)10-7(9)11/h1-4H,(H3,9,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Metobromuron 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron. 04Feb2014 2014 doi:10.2903/j.efsa.2014.3541
+Metobromuron 221-301-5 3060-89-7 single chemical entity Component is a metabolite of the substance 1-(4-bromophenyl)urea 1-(4-bromophenyl)urea Not in list C7H7BrN2O Brc1ccc(NC(N)=O)cc1 InChI=1/C7H7BrN2O/c8-5-1-3-6(4-2-5)10-7(9)11/h1-4H,(H3,9,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Metobromuron 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron. 04Feb2014 2014 doi:10.2903/j.efsa.2014.3541
+Metobromuron 221-301-5 3060-89-7 single chemical entity Component is a metabolite of the substance 1-(4-bromophenyl)urea 1-(4-bromophenyl)urea Not in list C7H7BrN2O Brc1ccc(NC(N)=O)cc1 InChI=1/C7H7BrN2O/c8-5-1-3-6(4-2-5)10-7(9)11/h1-4H,(H3,9,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Metobromuron 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron. 04Feb2014 2014 doi:10.2903/j.efsa.2014.3541
+Metobromuron 221-301-5 3060-89-7 single chemical entity Component is a metabolite of the substance 1-(4-bromophenyl)urea 1-(4-bromophenyl)urea Not in list C7H7BrN2O Brc1ccc(NC(N)=O)cc1 InChI=1/C7H7BrN2O/c8-5-1-3-6(4-2-5)10-7(9)11/h1-4H,(H3,9,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Metobromuron 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron. 04Feb2014 2014 doi:10.2903/j.efsa.2014.3541
+Metobromuron 221-301-5 3060-89-7 single chemical entity Component is a metabolite of the substance 1-(4-bromophenyl)urea 1-(4-bromophenyl)urea Not in list C7H7BrN2O Brc1ccc(NC(N)=O)cc1 InChI=1/C7H7BrN2O/c8-5-1-3-6(4-2-5)10-7(9)11/h1-4H,(H3,9,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Metobromuron 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron. 04Feb2014 2014 doi:10.2903/j.efsa.2014.3541
+Metobromuron 221-301-5 3060-89-7 single chemical entity Component is a metabolite of the substance 1-(4-bromophenyl)urea 1-(4-bromophenyl)urea Not in list C7H7BrN2O Brc1ccc(NC(N)=O)cc1 InChI=1/C7H7BrN2O/c8-5-1-3-6(4-2-5)10-7(9)11/h1-4H,(H3,9,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: France Metobromuron 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron. 04Feb2014 2014 doi:10.2903/j.efsa.2014.3541
+Metobromuron 221-301-5 3060-89-7 single chemical entity Component is a metabolite of the substance 1-(4-bromophenyl)urea 1-(4-bromophenyl)urea Not in list C7H7BrN2O Brc1ccc(NC(N)=O)cc1 InChI=1/C7H7BrN2O/c8-5-1-3-6(4-2-5)10-7(9)11/h1-4H,(H3,9,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: France Metobromuron 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron. 04Feb2014 2014 doi:10.2903/j.efsa.2014.3541
+Metobromuron 221-301-5 3060-89-7 single chemical entity Component is a metabolite of the substance 1-(4-bromophenyl)urea 1-(4-bromophenyl)urea Not in list C7H7BrN2O Brc1ccc(NC(N)=O)cc1 InChI=1/C7H7BrN2O/c8-5-1-3-6(4-2-5)10-7(9)11/h1-4H,(H3,9,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Metobromuron 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron. 04Feb2014 2014 doi:10.2903/j.efsa.2014.3541
+Metobromuron 221-301-5 3060-89-7 single chemical entity Component is a metabolite of the substance 1-(4-bromophenyl)urea 1-(4-bromophenyl)urea Not in list C7H7BrN2O Brc1ccc(NC(N)=O)cc1 InChI=1/C7H7BrN2O/c8-5-1-3-6(4-2-5)10-7(9)11/h1-4H,(H3,9,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Metobromuron 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron. 04Feb2014 2014 doi:10.2903/j.efsa.2014.3541
+Metobromuron 221-301-5 3060-89-7 single chemical entity Component is a metabolite of the substance 1-(4-bromophenyl)urea 1-(4-bromophenyl)urea Not in list C7H7BrN2O Brc1ccc(NC(N)=O)cc1 InChI=1/C7H7BrN2O/c8-5-1-3-6(4-2-5)10-7(9)11/h1-4H,(H3,9,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Metobromuron 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron. 04Feb2014 2014 doi:10.2903/j.efsa.2014.3541
+Metobromuron 221-301-5 3060-89-7 single chemical entity Component is a metabolite of the substance 1-(4-bromophenyl)-3-methoxyurea 1-(4-bromophenyl)-3-methoxyurea Not in list C8H9BrN2O2 Brc1ccc(NC(=O)NOC)cc1 InChI=1/C8H9BrN2O2/c1-13-11-8(12)10-7-4-2-6(9)3-5-7/h2-5H,1H3,(H2,10,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Metobromuron 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron. 04Feb2014 2014 doi:10.2903/j.efsa.2014.3541
+Metobromuron 221-301-5 3060-89-7 single chemical entity Component is a metabolite of the substance 1-(4-bromophenyl)-3-methoxyurea 1-(4-bromophenyl)-3-methoxyurea Not in list C8H9BrN2O2 Brc1ccc(NC(=O)NOC)cc1 InChI=1/C8H9BrN2O2/c1-13-11-8(12)10-7-4-2-6(9)3-5-7/h2-5H,1H3,(H2,10,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Metobromuron 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron. 04Feb2014 2014 doi:10.2903/j.efsa.2014.3541
+Metobromuron 221-301-5 3060-89-7 single chemical entity Component is a metabolite of the substance 1-(4-bromophenyl)-3-methoxyurea 1-(4-bromophenyl)-3-methoxyurea Not in list C8H9BrN2O2 Brc1ccc(NC(=O)NOC)cc1 InChI=1/C8H9BrN2O2/c1-13-11-8(12)10-7-4-2-6(9)3-5-7/h2-5H,1H3,(H2,10,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Metobromuron 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron. 04Feb2014 2014 doi:10.2903/j.efsa.2014.3541
+Metobromuron 221-301-5 3060-89-7 single chemical entity Component is a metabolite of the substance 1-(4-bromophenyl)-3-methoxyurea 1-(4-bromophenyl)-3-methoxyurea Not in list C8H9BrN2O2 Brc1ccc(NC(=O)NOC)cc1 InChI=1/C8H9BrN2O2/c1-13-11-8(12)10-7-4-2-6(9)3-5-7/h2-5H,1H3,(H2,10,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Metobromuron 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron. 04Feb2014 2014 doi:10.2903/j.efsa.2014.3541
+Metobromuron 221-301-5 3060-89-7 single chemical entity Component is a metabolite of the substance 1-(4-bromophenyl)-3-methoxyurea 1-(4-bromophenyl)-3-methoxyurea Not in list C8H9BrN2O2 Brc1ccc(NC(=O)NOC)cc1 InChI=1/C8H9BrN2O2/c1-13-11-8(12)10-7-4-2-6(9)3-5-7/h2-5H,1H3,(H2,10,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: France Metobromuron 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron. 04Feb2014 2014 doi:10.2903/j.efsa.2014.3541
+Metobromuron 221-301-5 3060-89-7 single chemical entity Component is a metabolite of the substance 1-(4-bromophenyl)-3-methoxyurea 1-(4-bromophenyl)-3-methoxyurea Not in list C8H9BrN2O2 Brc1ccc(NC(=O)NOC)cc1 InChI=1/C8H9BrN2O2/c1-13-11-8(12)10-7-4-2-6(9)3-5-7/h2-5H,1H3,(H2,10,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Metobromuron 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron. 04Feb2014 2014 doi:10.2903/j.efsa.2014.3541
+Metobromuron 221-301-5 3060-89-7 single chemical entity Component is a metabolite of the substance 1-(4-bromophenyl)-3-methoxyurea 1-(4-bromophenyl)-3-methoxyurea Not in list C8H9BrN2O2 Brc1ccc(NC(=O)NOC)cc1 InChI=1/C8H9BrN2O2/c1-13-11-8(12)10-7-4-2-6(9)3-5-7/h2-5H,1H3,(H2,10,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Metobromuron 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron. 04Feb2014 2014 doi:10.2903/j.efsa.2014.3541
+Metobromuron 221-301-5 3060-89-7 single chemical entity Component is a metabolite of the substance 1-(4-bromophenyl)-3-methoxyurea 1-(4-bromophenyl)-3-methoxyurea Not in list C8H9BrN2O2 Brc1ccc(NC(=O)NOC)cc1 InChI=1/C8H9BrN2O2/c1-13-11-8(12)10-7-4-2-6(9)3-5-7/h2-5H,1H3,(H2,10,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: France Metobromuron 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron. 04Feb2014 2014 doi:10.2903/j.efsa.2014.3541
+Metobromuron 221-301-5 3060-89-7 single chemical entity Component is a metabolite of the substance 1-(4-bromophenyl)-3-methoxyurea 1-(4-bromophenyl)-3-methoxyurea Not in list C8H9BrN2O2 Brc1ccc(NC(=O)NOC)cc1 InChI=1/C8H9BrN2O2/c1-13-11-8(12)10-7-4-2-6(9)3-5-7/h2-5H,1H3,(H2,10,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Metobromuron 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron. 04Feb2014 2014 doi:10.2903/j.efsa.2014.3541
+Metobromuron 221-301-5 3060-89-7 single chemical entity Component is a metabolite of the substance 1-(4-bromophenyl)-3-methoxyurea 1-(4-bromophenyl)-3-methoxyurea Not in list C8H9BrN2O2 Brc1ccc(NC(=O)NOC)cc1 InChI=1/C8H9BrN2O2/c1-13-11-8(12)10-7-4-2-6(9)3-5-7/h2-5H,1H3,(H2,10,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Metobromuron 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron. 04Feb2014 2014 doi:10.2903/j.efsa.2014.3541
+Metsulfuron-methyl 616-063-8 74223-64-6 single chemical entity Component is identical to the substance Metsulfuron-methyl 616-063-8 74223-64-6 methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate Metsulfuron-methyl C14H15N5O6S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes without Negative RMS: Slovenia - CoRMS: Sweden Metsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl 29Jan2015 2015 doi:10.2903/j.efsa.2015.3936
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance naphthalen-1-ol 201-969-4 90-15-3 naphthalen-1-ol Naphthol, 1- C10H8O C1=CC=C2C(=C1)C=CC=C2O InChI=1S/C10H8O/c11-10-7-3-5-8-4-1-2-6-9(8)10/h1-7,11H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: Denmark Napropamide (Addendum 1) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance naphthalen-1-ol 201-969-4 90-15-3 naphthalen-1-ol Naphthol, 1- C10H8O C1=CC=C2C(=C1)C=CC=C2O InChI=1S/C10H8O/c11-10-7-3-5-8-4-1-2-6-9(8)10/h1-7,11H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Denmark Napropamide (Addendum 1) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance naphthalen-1-ol 201-969-4 90-15-3 naphthalen-1-ol Naphthol, 1- C10H8O C1=CC=C2C(=C1)C=CC=C2O InChI=1S/C10H8O/c11-10-7-3-5-8-4-1-2-6-9(8)10/h1-7,11H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Denmark Napropamide (Addendum 1) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance naphthalen-1-ol 201-969-4 90-15-3 naphthalen-1-ol Naphthol, 1- C10H8O C1=CC=C2C(=C1)C=CC=C2O InChI=1S/C10H8O/c11-10-7-3-5-8-4-1-2-6-9(8)10/h1-7,11H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Denmark Napropamide (Addendum 1) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance naphthalen-1-ol 201-969-4 90-15-3 naphthalen-1-ol Naphthol, 1- C10H8O C1=CC=C2C(=C1)C=CC=C2O InChI=1S/C10H8O/c11-10-7-3-5-8-4-1-2-6-9(8)10/h1-7,11H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Denmark Napropamide (Addendum 1) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance naphthalen-1-ol 201-969-4 90-15-3 naphthalen-1-ol Naphthol, 1- C10H8O C1=CC=C2C(=C1)C=CC=C2O InChI=1S/C10H8O/c11-10-7-3-5-8-4-1-2-6-9(8)10/h1-7,11H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Denmark Napropamide (Addendum 1) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance naphthalen-1-ol 201-969-4 90-15-3 naphthalen-1-ol Naphthol, 1- C10H8O C1=CC=C2C(=C1)C=CC=C2O InChI=1S/C10H8O/c11-10-7-3-5-8-4-1-2-6-9(8)10/h1-7,11H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Denmark Napropamide (Addendum 1) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance naphthalen-1-ol 201-969-4 90-15-3 naphthalen-1-ol Naphthol, 1- C10H8O C1=CC=C2C(=C1)C=CC=C2O InChI=1S/C10H8O/c11-10-7-3-5-8-4-1-2-6-9(8)10/h1-7,11H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Denmark Napropamide (Addendum 1) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance naphthalen-1-ol 201-969-4 90-15-3 naphthalen-1-ol Naphthol, 1- C10H8O C1=CC=C2C(=C1)C=CC=C2O InChI=1S/C10H8O/c11-10-7-3-5-8-4-1-2-6-9(8)10/h1-7,11H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Denmark Napropamide (Addendum 1) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Napropamide 239-333-3 15299-99-7 single chemical entity Component is a metabolite of the substance naphthalen-1-ol 201-969-4 90-15-3 naphthalen-1-ol Naphthol, 1- C10H8O C1=CC=C2C(=C1)C=CC=C2O InChI=1S/C10H8O/c11-10-7-3-5-8-4-1-2-6-9(8)10/h1-7,11H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: Denmark Napropamide (Addendum 1) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide 15Apr2010 2010 doi:10.2903/j.efsa.2010.1565
+Orthosulfamuron 213464-77-8 single chemical entity Component is identical to the substance Orthosulfamuron 213464-77-8 1-(4,6-dimethoxypyrimidin-2-yl)-3-[2-(dimethylcarbamoyl)phenylsulfamoyl]urea Orthosulfamuron C16H20N6O6S CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C16H20N6O6S/c1-22(2)14(23)10-7-5-6-8-11(10)20-29(25,26)21-16(24)19-15-17-12(27-3)9-13(18-15)28-4/h5-9,20H,1-4H3,(H2,17,18,19,21,24) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Italy Orthosulfamuron (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is identical to the substance Orthosulfamuron 213464-77-8 1-(4,6-dimethoxypyrimidin-2-yl)-3-[2-(dimethylcarbamoyl)phenylsulfamoyl]urea Orthosulfamuron C16H20N6O6S CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C16H20N6O6S/c1-22(2)14(23)10-7-5-6-8-11(10)20-29(25,26)21-16(24)19-15-17-12(27-3)9-13(18-15)28-4/h5-9,20H,1-4H3,(H2,17,18,19,21,24) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Italy Orthosulfamuron (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is identical to the substance Orthosulfamuron 213464-77-8 1-(4,6-dimethoxypyrimidin-2-yl)-3-[2-(dimethylcarbamoyl)phenylsulfamoyl]urea Orthosulfamuron C16H20N6O6S CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C16H20N6O6S/c1-22(2)14(23)10-7-5-6-8-11(10)20-29(25,26)21-16(24)19-15-17-12(27-3)9-13(18-15)28-4/h5-9,20H,1-4H3,(H2,17,18,19,21,24) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Italy Orthosulfamuron (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is identical to the substance Orthosulfamuron 213464-77-8 1-(4,6-dimethoxypyrimidin-2-yl)-3-[2-(dimethylcarbamoyl)phenylsulfamoyl]urea Orthosulfamuron C16H20N6O6S CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C16H20N6O6S/c1-22(2)14(23)10-7-5-6-8-11(10)20-29(25,26)21-16(24)19-15-17-12(27-3)9-13(18-15)28-4/h5-9,20H,1-4H3,(H2,17,18,19,21,24) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Italy Orthosulfamuron (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is identical to the substance Orthosulfamuron 213464-77-8 1-(4,6-dimethoxypyrimidin-2-yl)-3-[2-(dimethylcarbamoyl)phenylsulfamoyl]urea Orthosulfamuron C16H20N6O6S CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C16H20N6O6S/c1-22(2)14(23)10-7-5-6-8-11(10)20-29(25,26)21-16(24)19-15-17-12(27-3)9-13(18-15)28-4/h5-9,20H,1-4H3,(H2,17,18,19,21,24) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Italy Orthosulfamuron (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is identical to the substance Orthosulfamuron 213464-77-8 1-(4,6-dimethoxypyrimidin-2-yl)-3-[2-(dimethylcarbamoyl)phenylsulfamoyl]urea Orthosulfamuron C16H20N6O6S CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C16H20N6O6S/c1-22(2)14(23)10-7-5-6-8-11(10)20-29(25,26)21-16(24)19-15-17-12(27-3)9-13(18-15)28-4/h5-9,20H,1-4H3,(H2,17,18,19,21,24) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Italy Orthosulfamuron (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is identical to the substance Orthosulfamuron 213464-77-8 1-(4,6-dimethoxypyrimidin-2-yl)-3-[2-(dimethylcarbamoyl)phenylsulfamoyl]urea Orthosulfamuron C16H20N6O6S CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C16H20N6O6S/c1-22(2)14(23)10-7-5-6-8-11(10)20-29(25,26)21-16(24)19-15-17-12(27-3)9-13(18-15)28-4/h5-9,20H,1-4H3,(H2,17,18,19,21,24) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Italy Orthosulfamuron (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is identical to the substance Orthosulfamuron 213464-77-8 1-(4,6-dimethoxypyrimidin-2-yl)-3-[2-(dimethylcarbamoyl)phenylsulfamoyl]urea Orthosulfamuron C16H20N6O6S CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C16H20N6O6S/c1-22(2)14(23)10-7-5-6-8-11(10)20-29(25,26)21-16(24)19-15-17-12(27-3)9-13(18-15)28-4/h5-9,20H,1-4H3,(H2,17,18,19,21,24) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Italy Orthosulfamuron (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is identical to the substance Orthosulfamuron 213464-77-8 1-(4,6-dimethoxypyrimidin-2-yl)-3-[2-(dimethylcarbamoyl)phenylsulfamoyl]urea Orthosulfamuron C16H20N6O6S CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C16H20N6O6S/c1-22(2)14(23)10-7-5-6-8-11(10)20-29(25,26)21-16(24)19-15-17-12(27-3)9-13(18-15)28-4/h5-9,20H,1-4H3,(H2,17,18,19,21,24) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Italy Orthosulfamuron (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is identical to the substance Orthosulfamuron 213464-77-8 1-(4,6-dimethoxypyrimidin-2-yl)-3-[2-(dimethylcarbamoyl)phenylsulfamoyl]urea Orthosulfamuron C16H20N6O6S CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C16H20N6O6S/c1-22(2)14(23)10-7-5-6-8-11(10)20-29(25,26)21-16(24)19-15-17-12(27-3)9-13(18-15)28-4/h5-9,20H,1-4H3,(H2,17,18,19,21,24) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Italy Orthosulfamuron (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is a metabolite of the substance 1-(4-hydroxy-6-methoxypyrimidin-2-yl)urea 1-(4-hydroxy-6-methoxypyrimidin-2-yl)urea Not in list C6H8N4O3 O=C(N)Nc1nc(O)cc(OC)n1 InChI=1S/C6H8N4O3/c1-13-4-2-3(11)8-6(9-4)10-5(7)12/h2H,1H3,(H4,7,8,9,10,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Italy Orthosulfamuron (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is a metabolite of the substance 1-(4-hydroxy-6-methoxypyrimidin-2-yl)urea 1-(4-hydroxy-6-methoxypyrimidin-2-yl)urea Not in list C6H8N4O3 O=C(N)Nc1nc(O)cc(OC)n1 InChI=1S/C6H8N4O3/c1-13-4-2-3(11)8-6(9-4)10-5(7)12/h2H,1H3,(H4,7,8,9,10,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Italy Orthosulfamuron (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is a metabolite of the substance 1-(4-hydroxy-6-methoxypyrimidin-2-yl)urea 1-(4-hydroxy-6-methoxypyrimidin-2-yl)urea Not in list C6H8N4O3 O=C(N)Nc1nc(O)cc(OC)n1 InChI=1S/C6H8N4O3/c1-13-4-2-3(11)8-6(9-4)10-5(7)12/h2H,1H3,(H4,7,8,9,10,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Italy Orthosulfamuron (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is a metabolite of the substance 1-(4-hydroxy-6-methoxypyrimidin-2-yl)urea 1-(4-hydroxy-6-methoxypyrimidin-2-yl)urea Not in list C6H8N4O3 O=C(N)Nc1nc(O)cc(OC)n1 InChI=1S/C6H8N4O3/c1-13-4-2-3(11)8-6(9-4)10-5(7)12/h2H,1H3,(H4,7,8,9,10,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Italy Orthosulfamuron (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is a metabolite of the substance 1-(4-hydroxy-6-methoxypyrimidin-2-yl)urea 1-(4-hydroxy-6-methoxypyrimidin-2-yl)urea Not in list C6H8N4O3 O=C(N)Nc1nc(O)cc(OC)n1 InChI=1S/C6H8N4O3/c1-13-4-2-3(11)8-6(9-4)10-5(7)12/h2H,1H3,(H4,7,8,9,10,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Italy Orthosulfamuron (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is a metabolite of the substance 1-(4-hydroxy-6-methoxypyrimidin-2-yl)urea 1-(4-hydroxy-6-methoxypyrimidin-2-yl)urea Not in list C6H8N4O3 O=C(N)Nc1nc(O)cc(OC)n1 InChI=1S/C6H8N4O3/c1-13-4-2-3(11)8-6(9-4)10-5(7)12/h2H,1H3,(H4,7,8,9,10,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Italy Orthosulfamuron (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is a metabolite of the substance 1-(4-hydroxy-6-methoxypyrimidin-2-yl)urea 1-(4-hydroxy-6-methoxypyrimidin-2-yl)urea Not in list C6H8N4O3 O=C(N)Nc1nc(O)cc(OC)n1 InChI=1S/C6H8N4O3/c1-13-4-2-3(11)8-6(9-4)10-5(7)12/h2H,1H3,(H4,7,8,9,10,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Italy Orthosulfamuron (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is a metabolite of the substance 1-(4-hydroxy-6-methoxypyrimidin-2-yl)urea 1-(4-hydroxy-6-methoxypyrimidin-2-yl)urea Not in list C6H8N4O3 O=C(N)Nc1nc(O)cc(OC)n1 InChI=1S/C6H8N4O3/c1-13-4-2-3(11)8-6(9-4)10-5(7)12/h2H,1H3,(H4,7,8,9,10,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Italy Orthosulfamuron (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is a metabolite of the substance 1-(4-hydroxy-6-methoxypyrimidin-2-yl)urea 1-(4-hydroxy-6-methoxypyrimidin-2-yl)urea Not in list C6H8N4O3 O=C(N)Nc1nc(O)cc(OC)n1 InChI=1S/C6H8N4O3/c1-13-4-2-3(11)8-6(9-4)10-5(7)12/h2H,1H3,(H4,7,8,9,10,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Italy Orthosulfamuron (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is a metabolite of the substance 1-(4-hydroxy-6-methoxypyrimidin-2-yl)urea 1-(4-hydroxy-6-methoxypyrimidin-2-yl)urea Not in list C6H8N4O3 O=C(N)Nc1nc(O)cc(OC)n1 InChI=1S/C6H8N4O3/c1-13-4-2-3(11)8-6(9-4)10-5(7)12/h2H,1H3,(H4,7,8,9,10,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Italy Orthosulfamuron (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is a metabolite of the substance 1-(4-hydroxy-6-methoxypyrimidin-2-yl)urea 1-(4-hydroxy-6-methoxypyrimidin-2-yl)urea Not in list C6H8N4O3 O=C(N)Nc1nc(O)cc(OC)n1 InChI=1S/C6H8N4O3/c1-13-4-2-3(11)8-6(9-4)10-5(7)12/h2H,1H3,(H4,7,8,9,10,11,12) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Italy Orthosulfamuron (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is a metabolite of the substance 1-(4-hydroxy-6-methoxypyrimidin-2-yl)urea 1-(4-hydroxy-6-methoxypyrimidin-2-yl)urea Not in list C6H8N4O3 O=C(N)Nc1nc(O)cc(OC)n1 InChI=1S/C6H8N4O3/c1-13-4-2-3(11)8-6(9-4)10-5(7)12/h2H,1H3,(H4,7,8,9,10,11,12) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Italy Orthosulfamuron (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is a metabolite of the substance 1-(4-hydroxy-6-methoxypyrimidin-2-yl)urea 1-(4-hydroxy-6-methoxypyrimidin-2-yl)urea Not in list C6H8N4O3 O=C(N)Nc1nc(O)cc(OC)n1 InChI=1S/C6H8N4O3/c1-13-4-2-3(11)8-6(9-4)10-5(7)12/h2H,1H3,(H4,7,8,9,10,11,12) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Italy Orthosulfamuron (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Orthosulfamuron 213464-77-8 single chemical entity Component is a metabolite of the substance 1-(4-hydroxy-6-methoxypyrimidin-2-yl)urea 1-(4-hydroxy-6-methoxypyrimidin-2-yl)urea Not in list C6H8N4O3 O=C(N)Nc1nc(O)cc(OC)n1 InChI=1S/C6H8N4O3/c1-13-4-2-3(11)8-6(9-4)10-5(7)12/h2H,1H3,(H4,7,8,9,10,11,12) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Italy Orthosulfamuron (Final Addendum to the DAR) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron 13Mar2014 2014 doi:10.2903/j.efsa.2014.3353
+Pyroxsulam 422556-08-9 single chemical entity Component is identical to the substance Pyroxsulam 422556-08-9 N-(5,7-dimethoxy-[1,2,4]triazolo[1,5-alpha]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide Pyroxsulam C14H13F3N6O5S COC1=CC(=NC2=NC(=NN12)NS(=O)(=O)C3=C(C=CN=C3OC)C(F)(F)F)OC InChI=1S/C14H13F3N6O5S/c1-26-8-6-9(27-2)23-13(19-8)20-12(21-23)22-29(24,25)10-7(14(15,16)17)4-5-18-11(10)28-3/h4-6H,1-3H3,(H,21,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) Not reported Not reported no data without Negative RMS: The United Kingdom Pyroxsulam 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam. 30Apr2013 2013 doi:10.2903/j.efsa.2013.3182
+Pyroxsulam 422556-08-9 single chemical entity Component is identical to the substance Pyroxsulam 422556-08-9 N-(5,7-dimethoxy-[1,2,4]triazolo[1,5-alpha]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide Pyroxsulam C14H13F3N6O5S COC1=CC(=NC2=NC(=NN12)NS(=O)(=O)C3=C(C=CN=C3OC)C(F)(F)F)OC InChI=1S/C14H13F3N6O5S/c1-26-8-6-9(27-2)23-13(19-8)20-12(21-23)22-29(24,25)10-7(14(15,16)17)4-5-18-11(10)28-3/h4-6H,1-3H3,(H,21,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No data Acceptable Salmonella typhimurium (as organism) Not reported Not reported no data with Negative RMS: The United Kingdom Pyroxsulam 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam. 30Apr2013 2013 doi:10.2903/j.efsa.2013.3182
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) Swiss 3 No data intraperitoneal 48.0000000000 h yes, concurrent vehicle not applicable Positive RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) Swiss 3 No data intraperitoneal 6.0000000000 h yes, concurrent vehicle not applicable Positive RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) Swiss 3 No data intraperitoneal 24.0000000000 h yes, concurrent vehicle not applicable Positive RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is identical to the substance Isoproturon 251-835-4 34123-59-6 1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Isoproturon C12H18N2O CC(C)C1=CC=C(C=C1)NC(=O)N(C)C InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Swiss No data intraperitoneal 6.0000000000 h yes, concurrent vehicle not applicable Positive RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance 3-{4-[(2RS-1-hydroxypropan-2-yl]phenyl}-1,1-dimethylurea 3-[4-(1-hydroxypropan-2-yl)phenyl]-1,1-dimethylurea Not in list C12H18N2O2 O=C(Nc1ccc(cc1)C(C)CO)N(C)C InChI=1S/C12H18N2O2/c1-9(8-15)10-4-6-11(7-5-10)13-12(16)14(2)3/h4-7,9,15H,8H2,1-3H3,(H,13,16) organic compound Other PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance 3-{4-[(2RS-1-hydroxypropan-2-yl]phenyl}-1,1-dimethylurea 3-[4-(1-hydroxypropan-2-yl)phenyl]-1,1-dimethylurea Not in list C12H18N2O2 O=C(Nc1ccc(cc1)C(C)CO)N(C)C InChI=1S/C12H18N2O2/c1-9(8-15)10-4-6-11(7-5-10)13-12(16)14(2)3/h4-7,9,15H,8H2,1-3H3,(H,13,16) organic compound Other PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance 3-{4-[(2RS-1-hydroxypropan-2-yl]phenyl}-1,1-dimethylurea 3-[4-(1-hydroxypropan-2-yl)phenyl]-1,1-dimethylurea Not in list C12H18N2O2 O=C(Nc1ccc(cc1)C(C)CO)N(C)C InChI=1S/C12H18N2O2/c1-9(8-15)10-4-6-11(7-5-10)13-12(16)14(2)3/h4-7,9,15H,8H2,1-3H3,(H,13,16) organic compound Other PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance 3-{4-[(2RS-1-hydroxypropan-2-yl]phenyl}-1,1-dimethylurea 3-[4-(1-hydroxypropan-2-yl)phenyl]-1,1-dimethylurea Not in list C12H18N2O2 O=C(Nc1ccc(cc1)C(C)CO)N(C)C InChI=1S/C12H18N2O2/c1-9(8-15)10-4-6-11(7-5-10)13-12(16)14(2)3/h4-7,9,15H,8H2,1-3H3,(H,13,16) organic compound Other PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance 3-{4-[(2RS-1-hydroxypropan-2-yl]phenyl}-1,1-dimethylurea 3-[4-(1-hydroxypropan-2-yl)phenyl]-1,1-dimethylurea Not in list C12H18N2O2 O=C(Nc1ccc(cc1)C(C)CO)N(C)C InChI=1S/C12H18N2O2/c1-9(8-15)10-4-6-11(7-5-10)13-12(16)14(2)3/h4-7,9,15H,8H2,1-3H3,(H,13,16) organic compound Other PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance 3-{4-[(2RS-1-hydroxypropan-2-yl]phenyl}-1,1-dimethylurea 3-[4-(1-hydroxypropan-2-yl)phenyl]-1,1-dimethylurea Not in list C12H18N2O2 O=C(Nc1ccc(cc1)C(C)CO)N(C)C InChI=1S/C12H18N2O2/c1-9(8-15)10-4-6-11(7-5-10)13-12(16)14(2)3/h4-7,9,15H,8H2,1-3H3,(H,13,16) organic compound Other PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance 3-{4-[(2RS-1-hydroxypropan-2-yl]phenyl}-1,1-dimethylurea 3-[4-(1-hydroxypropan-2-yl)phenyl]-1,1-dimethylurea Not in list C12H18N2O2 O=C(Nc1ccc(cc1)C(C)CO)N(C)C InChI=1S/C12H18N2O2/c1-9(8-15)10-4-6-11(7-5-10)13-12(16)14(2)3/h4-7,9,15H,8H2,1-3H3,(H,13,16) organic compound Other PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance 3-{4-[(2RS-1-hydroxypropan-2-yl]phenyl}-1,1-dimethylurea 3-[4-(1-hydroxypropan-2-yl)phenyl]-1,1-dimethylurea Not in list C12H18N2O2 O=C(Nc1ccc(cc1)C(C)CO)N(C)C InChI=1S/C12H18N2O2/c1-9(8-15)10-4-6-11(7-5-10)13-12(16)14(2)3/h4-7,9,15H,8H2,1-3H3,(H,13,16) organic compound Other PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance 3-{4-[(2RS-1-hydroxypropan-2-yl]phenyl}-1,1-dimethylurea 3-[4-(1-hydroxypropan-2-yl)phenyl]-1,1-dimethylurea Not in list C12H18N2O2 O=C(Nc1ccc(cc1)C(C)CO)N(C)C InChI=1S/C12H18N2O2/c1-9(8-15)10-4-6-11(7-5-10)13-12(16)14(2)3/h4-7,9,15H,8H2,1-3H3,(H,13,16) organic compound Other PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance 3-{4-[(2RS-1-hydroxypropan-2-yl]phenyl}-1,1-dimethylurea 3-[4-(1-hydroxypropan-2-yl)phenyl]-1,1-dimethylurea Not in list C12H18N2O2 O=C(Nc1ccc(cc1)C(C)CO)N(C)C InChI=1S/C12H18N2O2/c1-9(8-15)10-4-6-11(7-5-10)13-12(16)14(2)3/h4-7,9,15H,8H2,1-3H3,(H,13,16) organic compound Other PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance 3-{4-[(2RS-1-hydroxypropan-2-yl]phenyl}-1,1-dimethylurea 3-[4-(1-hydroxypropan-2-yl)phenyl]-1,1-dimethylurea Not in list C12H18N2O2 O=C(Nc1ccc(cc1)C(C)CO)N(C)C InChI=1S/C12H18N2O2/c1-9(8-15)10-4-6-11(7-5-10)13-12(16)14(2)3/h4-7,9,15H,8H2,1-3H3,(H,13,16) organic compound Other PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance 3-{4-[(2RS-1-hydroxypropan-2-yl]phenyl}-1,1-dimethylurea 3-[4-(1-hydroxypropan-2-yl)phenyl]-1,1-dimethylurea Not in list C12H18N2O2 O=C(Nc1ccc(cc1)C(C)CO)N(C)C InChI=1S/C12H18N2O2/c1-9(8-15)10-4-6-11(7-5-10)13-12(16)14(2)3/h4-7,9,15H,8H2,1-3H3,(H,13,16) organic compound Other PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance 3-{4-[(2RS-1-hydroxypropan-2-yl]phenyl}-1,1-dimethylurea 3-[4-(1-hydroxypropan-2-yl)phenyl]-1,1-dimethylurea Not in list C12H18N2O2 O=C(Nc1ccc(cc1)C(C)CO)N(C)C InChI=1S/C12H18N2O2/c1-9(8-15)10-4-6-11(7-5-10)13-12(16)14(2)3/h4-7,9,15H,8H2,1-3H3,(H,13,16) organic compound Other PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance 3-{4-[(2RS-1-hydroxypropan-2-yl]phenyl}-1,1-dimethylurea 3-[4-(1-hydroxypropan-2-yl)phenyl]-1,1-dimethylurea Not in list C12H18N2O2 O=C(Nc1ccc(cc1)C(C)CO)N(C)C InChI=1S/C12H18N2O2/c1-9(8-15)10-4-6-11(7-5-10)13-12(16)14(2)3/h4-7,9,15H,8H2,1-3H3,(H,13,16) organic compound Other PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance 3-[4-(2-hydroxy-2-propanyl)phenyl]-1,1-dimethylurea 3-[4-(2-hydroxypropan-2-yl)phenyl]-1,1-dimethylurea Not in list C12H18N2O2 O=C(Nc1ccc(cc1)C(C)(C)O)N(C)C InChI=1S/C12H18N2O2/c1-12(2,16)9-5-7-10(8-6-9)13-11(15)14(3)4/h5-8,16H,1-4H3,(H,13,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance 3-[4-(2-hydroxy-2-propanyl)phenyl]-1,1-dimethylurea 3-[4-(2-hydroxypropan-2-yl)phenyl]-1,1-dimethylurea Not in list C12H18N2O2 O=C(Nc1ccc(cc1)C(C)(C)O)N(C)C InChI=1S/C12H18N2O2/c1-12(2,16)9-5-7-10(8-6-9)13-11(15)14(3)4/h5-8,16H,1-4H3,(H,13,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance 3-[4-(2-hydroxy-2-propanyl)phenyl]-1,1-dimethylurea 3-[4-(2-hydroxypropan-2-yl)phenyl]-1,1-dimethylurea Not in list C12H18N2O2 O=C(Nc1ccc(cc1)C(C)(C)O)N(C)C InChI=1S/C12H18N2O2/c1-12(2,16)9-5-7-10(8-6-9)13-11(15)14(3)4/h5-8,16H,1-4H3,(H,13,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance 3-[4-(2-hydroxy-2-propanyl)phenyl]-1,1-dimethylurea 3-[4-(2-hydroxypropan-2-yl)phenyl]-1,1-dimethylurea Not in list C12H18N2O2 O=C(Nc1ccc(cc1)C(C)(C)O)N(C)C InChI=1S/C12H18N2O2/c1-12(2,16)9-5-7-10(8-6-9)13-11(15)14(3)4/h5-8,16H,1-4H3,(H,13,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance 3-[4-(2-hydroxy-2-propanyl)phenyl]-1,1-dimethylurea 3-[4-(2-hydroxypropan-2-yl)phenyl]-1,1-dimethylurea Not in list C12H18N2O2 O=C(Nc1ccc(cc1)C(C)(C)O)N(C)C InChI=1S/C12H18N2O2/c1-12(2,16)9-5-7-10(8-6-9)13-11(15)14(3)4/h5-8,16H,1-4H3,(H,13,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance 3-[4-(2-hydroxy-2-propanyl)phenyl]-1,1-dimethylurea 3-[4-(2-hydroxypropan-2-yl)phenyl]-1,1-dimethylurea Not in list C12H18N2O2 O=C(Nc1ccc(cc1)C(C)(C)O)N(C)C InChI=1S/C12H18N2O2/c1-12(2,16)9-5-7-10(8-6-9)13-11(15)14(3)4/h5-8,16H,1-4H3,(H,13,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance 3-[4-(2-hydroxy-2-propanyl)phenyl]-1,1-dimethylurea 3-[4-(2-hydroxypropan-2-yl)phenyl]-1,1-dimethylurea Not in list C12H18N2O2 O=C(Nc1ccc(cc1)C(C)(C)O)N(C)C InChI=1S/C12H18N2O2/c1-12(2,16)9-5-7-10(8-6-9)13-11(15)14(3)4/h5-8,16H,1-4H3,(H,13,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance 3-[4-(2-hydroxy-2-propanyl)phenyl]-1,1-dimethylurea 3-[4-(2-hydroxypropan-2-yl)phenyl]-1,1-dimethylurea Not in list C12H18N2O2 O=C(Nc1ccc(cc1)C(C)(C)O)N(C)C InChI=1S/C12H18N2O2/c1-12(2,16)9-5-7-10(8-6-9)13-11(15)14(3)4/h5-8,16H,1-4H3,(H,13,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance 3-[4-(2-hydroxy-2-propanyl)phenyl]-1,1-dimethylurea 3-[4-(2-hydroxypropan-2-yl)phenyl]-1,1-dimethylurea Not in list C12H18N2O2 O=C(Nc1ccc(cc1)C(C)(C)O)N(C)C InChI=1S/C12H18N2O2/c1-12(2,16)9-5-7-10(8-6-9)13-11(15)14(3)4/h5-8,16H,1-4H3,(H,13,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance 3-[4-(2-hydroxy-2-propanyl)phenyl]-1,1-dimethylurea 3-[4-(2-hydroxypropan-2-yl)phenyl]-1,1-dimethylurea Not in list C12H18N2O2 O=C(Nc1ccc(cc1)C(C)(C)O)N(C)C InChI=1S/C12H18N2O2/c1-12(2,16)9-5-7-10(8-6-9)13-11(15)14(3)4/h5-8,16H,1-4H3,(H,13,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance 3-[4-(2-hydroxy-2-propanyl)phenyl]-1,1-dimethylurea 3-[4-(2-hydroxypropan-2-yl)phenyl]-1,1-dimethylurea Not in list C12H18N2O2 O=C(Nc1ccc(cc1)C(C)(C)O)N(C)C InChI=1S/C12H18N2O2/c1-12(2,16)9-5-7-10(8-6-9)13-11(15)14(3)4/h5-8,16H,1-4H3,(H,13,15) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance 3-[4-(2-hydroxy-2-propanyl)phenyl]-1,1-dimethylurea 3-[4-(2-hydroxypropan-2-yl)phenyl]-1,1-dimethylurea Not in list C12H18N2O2 O=C(Nc1ccc(cc1)C(C)(C)O)N(C)C InChI=1S/C12H18N2O2/c1-12(2,16)9-5-7-10(8-6-9)13-11(15)14(3)4/h5-8,16H,1-4H3,(H,13,15) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance 3-[4-(2-hydroxy-2-propanyl)phenyl]-1,1-dimethylurea 3-[4-(2-hydroxypropan-2-yl)phenyl]-1,1-dimethylurea Not in list C12H18N2O2 O=C(Nc1ccc(cc1)C(C)(C)O)N(C)C InChI=1S/C12H18N2O2/c1-12(2,16)9-5-7-10(8-6-9)13-11(15)14(3)4/h5-8,16H,1-4H3,(H,13,15) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance 3-[4-(2-hydroxy-2-propanyl)phenyl]-1,1-dimethylurea 3-[4-(2-hydroxypropan-2-yl)phenyl]-1,1-dimethylurea Not in list C12H18N2O2 O=C(Nc1ccc(cc1)C(C)(C)O)N(C)C InChI=1S/C12H18N2O2/c1-12(2,16)9-5-7-10(8-6-9)13-11(15)14(3)4/h5-8,16H,1-4H3,(H,13,15) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance 1-(4-isopropylphenyl)urea (4-propan-2-ylphenyl)urea Not in list C10H14N2O O=C(N)Nc1ccc(cc1)C(C)C InChI=1S/C10H14N2O/c1-7(2)8-3-5-9(6-4-8)12-10(11)13/h3-7H,1-2H3,(H3,11,12,13) organic compound Other PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance 1-(4-isopropylphenyl)urea (4-propan-2-ylphenyl)urea Not in list C10H14N2O O=C(N)Nc1ccc(cc1)C(C)C InChI=1S/C10H14N2O/c1-7(2)8-3-5-9(6-4-8)12-10(11)13/h3-7H,1-2H3,(H3,11,12,13) organic compound Other PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance 1-(4-isopropylphenyl)urea (4-propan-2-ylphenyl)urea Not in list C10H14N2O O=C(N)Nc1ccc(cc1)C(C)C InChI=1S/C10H14N2O/c1-7(2)8-3-5-9(6-4-8)12-10(11)13/h3-7H,1-2H3,(H3,11,12,13) organic compound Other PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance 1-(4-isopropylphenyl)urea (4-propan-2-ylphenyl)urea Not in list C10H14N2O O=C(N)Nc1ccc(cc1)C(C)C InChI=1S/C10H14N2O/c1-7(2)8-3-5-9(6-4-8)12-10(11)13/h3-7H,1-2H3,(H3,11,12,13) organic compound Other PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance 1-(4-isopropylphenyl)urea (4-propan-2-ylphenyl)urea Not in list C10H14N2O O=C(N)Nc1ccc(cc1)C(C)C InChI=1S/C10H14N2O/c1-7(2)8-3-5-9(6-4-8)12-10(11)13/h3-7H,1-2H3,(H3,11,12,13) organic compound Other PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance 1-(4-isopropylphenyl)urea (4-propan-2-ylphenyl)urea Not in list C10H14N2O O=C(N)Nc1ccc(cc1)C(C)C InChI=1S/C10H14N2O/c1-7(2)8-3-5-9(6-4-8)12-10(11)13/h3-7H,1-2H3,(H3,11,12,13) organic compound Other PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance 1-(4-isopropylphenyl)urea (4-propan-2-ylphenyl)urea Not in list C10H14N2O O=C(N)Nc1ccc(cc1)C(C)C InChI=1S/C10H14N2O/c1-7(2)8-3-5-9(6-4-8)12-10(11)13/h3-7H,1-2H3,(H3,11,12,13) organic compound Other PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance 1-(4-isopropylphenyl)urea (4-propan-2-ylphenyl)urea Not in list C10H14N2O O=C(N)Nc1ccc(cc1)C(C)C InChI=1S/C10H14N2O/c1-7(2)8-3-5-9(6-4-8)12-10(11)13/h3-7H,1-2H3,(H3,11,12,13) organic compound Other PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance 1-(4-isopropylphenyl)urea (4-propan-2-ylphenyl)urea Not in list C10H14N2O O=C(N)Nc1ccc(cc1)C(C)C InChI=1S/C10H14N2O/c1-7(2)8-3-5-9(6-4-8)12-10(11)13/h3-7H,1-2H3,(H3,11,12,13) organic compound Other PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance 1-(4-isopropylphenyl)urea (4-propan-2-ylphenyl)urea Not in list C10H14N2O O=C(N)Nc1ccc(cc1)C(C)C InChI=1S/C10H14N2O/c1-7(2)8-3-5-9(6-4-8)12-10(11)13/h3-7H,1-2H3,(H3,11,12,13) organic compound Other PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance 1-(4-isopropylphenyl)urea (4-propan-2-ylphenyl)urea Not in list C10H14N2O O=C(N)Nc1ccc(cc1)C(C)C InChI=1S/C10H14N2O/c1-7(2)8-3-5-9(6-4-8)12-10(11)13/h3-7H,1-2H3,(H3,11,12,13) organic compound Other PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance 1-(4-isopropylphenyl)urea (4-propan-2-ylphenyl)urea Not in list C10H14N2O O=C(N)Nc1ccc(cc1)C(C)C InChI=1S/C10H14N2O/c1-7(2)8-3-5-9(6-4-8)12-10(11)13/h3-7H,1-2H3,(H3,11,12,13) organic compound Other PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance 1-(4-isopropylphenyl)urea (4-propan-2-ylphenyl)urea Not in list C10H14N2O O=C(N)Nc1ccc(cc1)C(C)C InChI=1S/C10H14N2O/c1-7(2)8-3-5-9(6-4-8)12-10(11)13/h3-7H,1-2H3,(H3,11,12,13) organic compound Other PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance 1-(4-isopropylphenyl)urea (4-propan-2-ylphenyl)urea Not in list C10H14N2O O=C(N)Nc1ccc(cc1)C(C)C InChI=1S/C10H14N2O/c1-7(2)8-3-5-9(6-4-8)12-10(11)13/h3-7H,1-2H3,(H3,11,12,13) organic compound Other PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance (2RS)-2-{4-[(dimethylcarbamoyl)amino]phenyl}propanoic acid 2-{4-[(dimethylcarbamoyl)amino]phenyl}propanoic acid Not in list C12H16N2O3 O=C(Nc1ccc(cc1)C(C)C(=O)O)N(C)C InChI=1S/C12H16N2O3/c1-8(11(15)16)9-4-6-10(7-5-9)13-12(17)14(2)3/h4-8H,1-3H3,(H,13,17)(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance (2RS)-2-{4-[(dimethylcarbamoyl)amino]phenyl}propanoic acid 2-{4-[(dimethylcarbamoyl)amino]phenyl}propanoic acid Not in list C12H16N2O3 O=C(Nc1ccc(cc1)C(C)C(=O)O)N(C)C InChI=1S/C12H16N2O3/c1-8(11(15)16)9-4-6-10(7-5-9)13-12(17)14(2)3/h4-8H,1-3H3,(H,13,17)(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance (2RS)-2-{4-[(dimethylcarbamoyl)amino]phenyl}propanoic acid 2-{4-[(dimethylcarbamoyl)amino]phenyl}propanoic acid Not in list C12H16N2O3 O=C(Nc1ccc(cc1)C(C)C(=O)O)N(C)C InChI=1S/C12H16N2O3/c1-8(11(15)16)9-4-6-10(7-5-9)13-12(17)14(2)3/h4-8H,1-3H3,(H,13,17)(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance (2RS)-2-{4-[(dimethylcarbamoyl)amino]phenyl}propanoic acid 2-{4-[(dimethylcarbamoyl)amino]phenyl}propanoic acid Not in list C12H16N2O3 O=C(Nc1ccc(cc1)C(C)C(=O)O)N(C)C InChI=1S/C12H16N2O3/c1-8(11(15)16)9-4-6-10(7-5-9)13-12(17)14(2)3/h4-8H,1-3H3,(H,13,17)(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance (2RS)-2-{4-[(dimethylcarbamoyl)amino]phenyl}propanoic acid 2-{4-[(dimethylcarbamoyl)amino]phenyl}propanoic acid Not in list C12H16N2O3 O=C(Nc1ccc(cc1)C(C)C(=O)O)N(C)C InChI=1S/C12H16N2O3/c1-8(11(15)16)9-4-6-10(7-5-9)13-12(17)14(2)3/h4-8H,1-3H3,(H,13,17)(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance (2RS)-2-{4-[(dimethylcarbamoyl)amino]phenyl}propanoic acid 2-{4-[(dimethylcarbamoyl)amino]phenyl}propanoic acid Not in list C12H16N2O3 O=C(Nc1ccc(cc1)C(C)C(=O)O)N(C)C InChI=1S/C12H16N2O3/c1-8(11(15)16)9-4-6-10(7-5-9)13-12(17)14(2)3/h4-8H,1-3H3,(H,13,17)(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance (2RS)-2-{4-[(dimethylcarbamoyl)amino]phenyl}propanoic acid 2-{4-[(dimethylcarbamoyl)amino]phenyl}propanoic acid Not in list C12H16N2O3 O=C(Nc1ccc(cc1)C(C)C(=O)O)N(C)C InChI=1S/C12H16N2O3/c1-8(11(15)16)9-4-6-10(7-5-9)13-12(17)14(2)3/h4-8H,1-3H3,(H,13,17)(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance (2RS)-2-{4-[(dimethylcarbamoyl)amino]phenyl}propanoic acid 2-{4-[(dimethylcarbamoyl)amino]phenyl}propanoic acid Not in list C12H16N2O3 O=C(Nc1ccc(cc1)C(C)C(=O)O)N(C)C InChI=1S/C12H16N2O3/c1-8(11(15)16)9-4-6-10(7-5-9)13-12(17)14(2)3/h4-8H,1-3H3,(H,13,17)(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance (2RS)-2-{4-[(dimethylcarbamoyl)amino]phenyl}propanoic acid 2-{4-[(dimethylcarbamoyl)amino]phenyl}propanoic acid Not in list C12H16N2O3 O=C(Nc1ccc(cc1)C(C)C(=O)O)N(C)C InChI=1S/C12H16N2O3/c1-8(11(15)16)9-4-6-10(7-5-9)13-12(17)14(2)3/h4-8H,1-3H3,(H,13,17)(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance (2RS)-2-{4-[(dimethylcarbamoyl)amino]phenyl}propanoic acid 2-{4-[(dimethylcarbamoyl)amino]phenyl}propanoic acid Not in list C12H16N2O3 O=C(Nc1ccc(cc1)C(C)C(=O)O)N(C)C InChI=1S/C12H16N2O3/c1-8(11(15)16)9-4-6-10(7-5-9)13-12(17)14(2)3/h4-8H,1-3H3,(H,13,17)(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance (2RS)-2-{4-[(dimethylcarbamoyl)amino]phenyl}propanoic acid 2-{4-[(dimethylcarbamoyl)amino]phenyl}propanoic acid Not in list C12H16N2O3 O=C(Nc1ccc(cc1)C(C)C(=O)O)N(C)C InChI=1S/C12H16N2O3/c1-8(11(15)16)9-4-6-10(7-5-9)13-12(17)14(2)3/h4-8H,1-3H3,(H,13,17)(H,15,16) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance (2RS)-2-{4-[(dimethylcarbamoyl)amino]phenyl}propanoic acid 2-{4-[(dimethylcarbamoyl)amino]phenyl}propanoic acid Not in list C12H16N2O3 O=C(Nc1ccc(cc1)C(C)C(=O)O)N(C)C InChI=1S/C12H16N2O3/c1-8(11(15)16)9-4-6-10(7-5-9)13-12(17)14(2)3/h4-8H,1-3H3,(H,13,17)(H,15,16) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance (2RS)-2-{4-[(dimethylcarbamoyl)amino]phenyl}propanoic acid 2-{4-[(dimethylcarbamoyl)amino]phenyl}propanoic acid Not in list C12H16N2O3 O=C(Nc1ccc(cc1)C(C)C(=O)O)N(C)C InChI=1S/C12H16N2O3/c1-8(11(15)16)9-4-6-10(7-5-9)13-12(17)14(2)3/h4-8H,1-3H3,(H,13,17)(H,15,16) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Isoproturon 251-835-4 34123-59-6 single chemical entity Component is a metabolite of the substance (2RS)-2-{4-[(dimethylcarbamoyl)amino]phenyl}propanoic acid 2-{4-[(dimethylcarbamoyl)amino]phenyl}propanoic acid Not in list C12H16N2O3 O=C(Nc1ccc(cc1)C(C)C(=O)O)N(C)C InChI=1S/C12H16N2O3/c1-8(11(15)16)9-4-6-10(7-5-9)13-12(17)14(2)3/h4-8H,1-3H3,(H,13,17)(H,15,16) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Czech Republic Isoproturon (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon 20Aug2015 2015 doi:10.2903/j.efsa.2015.4206
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported no data with Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported no data without Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported no data without Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Mesotrione 600-533-4 104206-82-8 single chemical entity Component is identical to the substance Mesotrione 600-533-4 104206-82-8 2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione Mesotrione C14H13NO7S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported no data with Negative RMS: The United Kingdom - CoRMS: Belgium Mesotrione (ZA1296) 2015 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance mesotrione 07Mar2016 2016 doi:10.2903/j.efsa.2016.4419
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is identical to the substance Metalaxyl-M 615-135-6 70630-17-0 methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate Metalaxyl-M C15H21NO4 CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 5 Male intraperitoneal 24.0000000000 h yes not applicable Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance (R)-2-[(2,6-Dimethyl-phenyl)-(2-methoxy-acetyl)-amino]-propionic acid (2R)-2-[(2,6-dimethylphenyl)(methoxyacetyl)amino]propanoic acid Not in list C14H19NO4 C[C@@H](N(C(=O)COC)c1c(C)cccc1C)C(=O)O InChI=1S/C14H19NO4/c1-9-6-5-7-10(2)13(9)15(11(3)14(17)18)12(16)8-19-4/h5-7,11H,8H2,1-4H3,(H,17,18)/t11-/m1/s1 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Positive RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Metalaxyl-M 615-135-6 70630-17-0 single chemical entity Component is a metabolite of the substance (R)-2-[(2,6-Dimethyl-phenyl)-(2-methoxy-acetyl)-amino]-propionic acid (2R)-2-[(2,6-dimethylphenyl)(methoxyacetyl)amino]propanoic acid Not in list C14H19NO4 C[C@@H](N(C(=O)COC)c1c(C)cccc1C)C(=O)O InChI=1S/C14H19NO4/c1-9-6-5-7-10(2)13(9)15(11(3)14(17)18)12(16)8-19-4/h5-7,11H,8H2,1-4H3,(H,17,18)/t11-/m1/s1 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Belgium - CoRMS: Greece Metalaxyl-M 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M 03Mar2015 2015 doi:10.2903/j.efsa.2015.3999
+Ethephon 240-718-3 16672-87-0 single chemical entity Component is identical to the substance Ethephon 240-718-3 16672-87-0 (2-chloroethyl)phosphonic acid Ethephon C2H6ClO3P ClCCP(O)(=O)O InChI=1S/C2H6ClO3P/c3-1-2-7(4,5)6/h1-2H2,(H2,4,5,6) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Ethephon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethephon 15Jan2009 2009 doi:10.2903/j.efsa.2009.174r
+Ethephon 240-718-3 16672-87-0 single chemical entity Component is identical to the substance Ethephon 240-718-3 16672-87-0 (2-chloroethyl)phosphonic acid Ethephon C2H6ClO3P ClCCP(O)(=O)O InChI=1S/C2H6ClO3P/c3-1-2-7(4,5)6/h1-2H2,(H2,4,5,6) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Positive RMS: The Netherlands Ethephon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethephon 15Jan2009 2009 doi:10.2903/j.efsa.2009.174r
+Ethephon 240-718-3 16672-87-0 single chemical entity Component is identical to the substance Ethephon 240-718-3 16672-87-0 (2-chloroethyl)phosphonic acid Ethephon C2H6ClO3P ClCCP(O)(=O)O InChI=1S/C2H6ClO3P/c3-1-2-7(4,5)6/h1-2H2,(H2,4,5,6) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Ethephon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethephon 15Jan2009 2009 doi:10.2903/j.efsa.2009.174r
+Ethephon 240-718-3 16672-87-0 single chemical entity Component is identical to the substance Ethephon 240-718-3 16672-87-0 (2-chloroethyl)phosphonic acid Ethephon C2H6ClO3P ClCCP(O)(=O)O InChI=1S/C2H6ClO3P/c3-1-2-7(4,5)6/h1-2H2,(H2,4,5,6) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Ethephon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethephon 15Jan2009 2009 doi:10.2903/j.efsa.2009.174r
+Ethephon 240-718-3 16672-87-0 single chemical entity Component is identical to the substance Ethephon 240-718-3 16672-87-0 (2-chloroethyl)phosphonic acid Ethephon C2H6ClO3P ClCCP(O)(=O)O InChI=1S/C2H6ClO3P/c3-1-2-7(4,5)6/h1-2H2,(H2,4,5,6) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Ethephon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethephon 15Jan2009 2009 doi:10.2903/j.efsa.2009.174r
+Ethephon 240-718-3 16672-87-0 single chemical entity Component is identical to the substance Ethephon 240-718-3 16672-87-0 (2-chloroethyl)phosphonic acid Ethephon C2H6ClO3P ClCCP(O)(=O)O InChI=1S/C2H6ClO3P/c3-1-2-7(4,5)6/h1-2H2,(H2,4,5,6) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Ethephon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethephon 15Jan2009 2009 doi:10.2903/j.efsa.2009.174r
+Ethephon 240-718-3 16672-87-0 single chemical entity Component is identical to the substance Ethephon 240-718-3 16672-87-0 (2-chloroethyl)phosphonic acid Ethephon C2H6ClO3P ClCCP(O)(=O)O InChI=1S/C2H6ClO3P/c3-1-2-7(4,5)6/h1-2H2,(H2,4,5,6) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Positive RMS: The Netherlands Ethephon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethephon 15Jan2009 2009 doi:10.2903/j.efsa.2009.174r
+Ethephon 240-718-3 16672-87-0 single chemical entity Component is identical to the substance Ethephon 240-718-3 16672-87-0 (2-chloroethyl)phosphonic acid Ethephon C2H6ClO3P ClCCP(O)(=O)O InChI=1S/C2H6ClO3P/c3-1-2-7(4,5)6/h1-2H2,(H2,4,5,6) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Ethephon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethephon 15Jan2009 2009 doi:10.2903/j.efsa.2009.174r
+Ethephon 240-718-3 16672-87-0 single chemical entity Component is identical to the substance Ethephon 240-718-3 16672-87-0 (2-chloroethyl)phosphonic acid Ethephon C2H6ClO3P ClCCP(O)(=O)O InChI=1S/C2H6ClO3P/c3-1-2-7(4,5)6/h1-2H2,(H2,4,5,6) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Ethephon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethephon 15Jan2009 2009 doi:10.2903/j.efsa.2009.174r
+Ethephon 240-718-3 16672-87-0 single chemical entity Component is identical to the substance Ethephon 240-718-3 16672-87-0 (2-chloroethyl)phosphonic acid Ethephon C2H6ClO3P ClCCP(O)(=O)O InChI=1S/C2H6ClO3P/c3-1-2-7(4,5)6/h1-2H2,(H2,4,5,6) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Ethephon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethephon 15Jan2009 2009 doi:10.2903/j.efsa.2009.174r
+Ethephon 240-718-3 16672-87-0 single chemical entity Component is identical to the substance Ethephon 240-718-3 16672-87-0 (2-chloroethyl)phosphonic acid Ethephon C2H6ClO3P ClCCP(O)(=O)O InChI=1S/C2H6ClO3P/c3-1-2-7(4,5)6/h1-2H2,(H2,4,5,6) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: The Netherlands Ethephon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethephon 15Jan2009 2009 doi:10.2903/j.efsa.2009.174r
+Ethephon 240-718-3 16672-87-0 single chemical entity Component is identical to the substance Ethephon 240-718-3 16672-87-0 (2-chloroethyl)phosphonic acid Ethephon C2H6ClO3P ClCCP(O)(=O)O InChI=1S/C2H6ClO3P/c3-1-2-7(4,5)6/h1-2H2,(H2,4,5,6) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: The Netherlands Ethephon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethephon 15Jan2009 2009 doi:10.2903/j.efsa.2009.174r
+Ethephon 240-718-3 16672-87-0 single chemical entity Component is identical to the substance Ethephon 240-718-3 16672-87-0 (2-chloroethyl)phosphonic acid Ethephon C2H6ClO3P ClCCP(O)(=O)O InChI=1S/C2H6ClO3P/c3-1-2-7(4,5)6/h1-2H2,(H2,4,5,6) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: The Netherlands Ethephon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethephon 15Jan2009 2009 doi:10.2903/j.efsa.2009.174r
+Ethephon 240-718-3 16672-87-0 single chemical entity Component is identical to the substance Ethephon 240-718-3 16672-87-0 (2-chloroethyl)phosphonic acid Ethephon C2H6ClO3P ClCCP(O)(=O)O InChI=1S/C2H6ClO3P/c3-1-2-7(4,5)6/h1-2H2,(H2,4,5,6) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: The Netherlands Ethephon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethephon 15Jan2009 2009 doi:10.2903/j.efsa.2009.174r
+Ethephon 240-718-3 16672-87-0 single chemical entity Component is identical to the substance Ethephon 240-718-3 16672-87-0 (2-chloroethyl)phosphonic acid Ethephon C2H6ClO3P ClCCP(O)(=O)O InChI=1S/C2H6ClO3P/c3-1-2-7(4,5)6/h1-2H2,(H2,4,5,6) organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Rat (as animal) hepatocytes Not reported yes without Negative RMS: The Netherlands Ethephon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethephon 15Jan2009 2009 doi:10.2903/j.efsa.2009.174r
+Ethephon 240-718-3 16672-87-0 single chemical entity Component is identical to the substance Ethephon 240-718-3 16672-87-0 (2-chloroethyl)phosphonic acid Ethephon C2H6ClO3P ClCCP(O)(=O)O InChI=1S/C2H6ClO3P/c3-1-2-7(4,5)6/h1-2H2,(H2,4,5,6) organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Wistar 4 Male oral: unspecified 14.0000000000 h yes not applicable Negative RMS: The Netherlands Ethephon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethephon 15Jan2009 2009 doi:10.2903/j.efsa.2009.174r
+Ethephon 240-718-3 16672-87-0 single chemical entity Component is identical to the substance Ethephon 240-718-3 16672-87-0 (2-chloroethyl)phosphonic acid Ethephon C2H6ClO3P ClCCP(O)(=O)O InChI=1S/C2H6ClO3P/c3-1-2-7(4,5)6/h1-2H2,(H2,4,5,6) organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Wistar 4 Male oral: unspecified 4.0000000000 h yes not applicable Negative RMS: The Netherlands Ethephon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethephon 15Jan2009 2009 doi:10.2903/j.efsa.2009.174r
+Ethephon 240-718-3 16672-87-0 single chemical entity Component is a metabolite of the substance 2-hydroxyethylphosphonic acid 245-370-6 22987-21-9 2-hydroxyethylphosphonic acid 2-Hydroxyethylphosphonic acid C2H7O4P C(CP(=O)(O)O)O InChI=1S/C2H7O4P/c3-1-2-7(4,5)6/h3H,1-2H2,(H2,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The Netherlands Ethephon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethephon 15Jan2009 2009 doi:10.2903/j.efsa.2009.174r
+Ethephon 240-718-3 16672-87-0 single chemical entity Component is a metabolite of the substance 2-hydroxyethylphosphonic acid 245-370-6 22987-21-9 2-hydroxyethylphosphonic acid 2-Hydroxyethylphosphonic acid C2H7O4P C(CP(=O)(O)O)O InChI=1S/C2H7O4P/c3-1-2-7(4,5)6/h3H,1-2H2,(H2,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The Netherlands Ethephon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethephon 15Jan2009 2009 doi:10.2903/j.efsa.2009.174r
+Ethephon 240-718-3 16672-87-0 single chemical entity Component is a metabolite of the substance 2-hydroxyethylphosphonic acid 245-370-6 22987-21-9 2-hydroxyethylphosphonic acid 2-Hydroxyethylphosphonic acid C2H7O4P C(CP(=O)(O)O)O InChI=1S/C2H7O4P/c3-1-2-7(4,5)6/h3H,1-2H2,(H2,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The Netherlands Ethephon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethephon 15Jan2009 2009 doi:10.2903/j.efsa.2009.174r
+Ethephon 240-718-3 16672-87-0 single chemical entity Component is a metabolite of the substance 2-hydroxyethylphosphonic acid 245-370-6 22987-21-9 2-hydroxyethylphosphonic acid 2-Hydroxyethylphosphonic acid C2H7O4P C(CP(=O)(O)O)O InChI=1S/C2H7O4P/c3-1-2-7(4,5)6/h3H,1-2H2,(H2,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The Netherlands Ethephon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethephon 15Jan2009 2009 doi:10.2903/j.efsa.2009.174r
+Ethephon 240-718-3 16672-87-0 single chemical entity Component is a metabolite of the substance 2-hydroxyethylphosphonic acid 245-370-6 22987-21-9 2-hydroxyethylphosphonic acid 2-Hydroxyethylphosphonic acid C2H7O4P C(CP(=O)(O)O)O InChI=1S/C2H7O4P/c3-1-2-7(4,5)6/h3H,1-2H2,(H2,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes with Negative RMS: The Netherlands Ethephon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethephon 15Jan2009 2009 doi:10.2903/j.efsa.2009.174r
+Ethephon 240-718-3 16672-87-0 single chemical entity Component is a metabolite of the substance 2-hydroxyethylphosphonic acid 245-370-6 22987-21-9 2-hydroxyethylphosphonic acid 2-Hydroxyethylphosphonic acid C2H7O4P C(CP(=O)(O)O)O InChI=1S/C2H7O4P/c3-1-2-7(4,5)6/h3H,1-2H2,(H2,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The Netherlands Ethephon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethephon 15Jan2009 2009 doi:10.2903/j.efsa.2009.174r
+Ethephon 240-718-3 16672-87-0 single chemical entity Component is a metabolite of the substance 2-hydroxyethylphosphonic acid 245-370-6 22987-21-9 2-hydroxyethylphosphonic acid 2-Hydroxyethylphosphonic acid C2H7O4P C(CP(=O)(O)O)O InChI=1S/C2H7O4P/c3-1-2-7(4,5)6/h3H,1-2H2,(H2,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The Netherlands Ethephon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethephon 15Jan2009 2009 doi:10.2903/j.efsa.2009.174r
+Ethephon 240-718-3 16672-87-0 single chemical entity Component is a metabolite of the substance 2-hydroxyethylphosphonic acid 245-370-6 22987-21-9 2-hydroxyethylphosphonic acid 2-Hydroxyethylphosphonic acid C2H7O4P C(CP(=O)(O)O)O InChI=1S/C2H7O4P/c3-1-2-7(4,5)6/h3H,1-2H2,(H2,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes without Negative RMS: The Netherlands Ethephon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethephon 15Jan2009 2009 doi:10.2903/j.efsa.2009.174r
+Ethephon 240-718-3 16672-87-0 single chemical entity Component is a metabolite of the substance 2-hydroxyethylphosphonic acid 245-370-6 22987-21-9 2-hydroxyethylphosphonic acid 2-Hydroxyethylphosphonic acid C2H7O4P C(CP(=O)(O)O)O InChI=1S/C2H7O4P/c3-1-2-7(4,5)6/h3H,1-2H2,(H2,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The Netherlands Ethephon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethephon 15Jan2009 2009 doi:10.2903/j.efsa.2009.174r
+Ethephon 240-718-3 16672-87-0 single chemical entity Component is a metabolite of the substance 2-hydroxyethylphosphonic acid 245-370-6 22987-21-9 2-hydroxyethylphosphonic acid 2-Hydroxyethylphosphonic acid C2H7O4P C(CP(=O)(O)O)O InChI=1S/C2H7O4P/c3-1-2-7(4,5)6/h3H,1-2H2,(H2,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The Netherlands Ethephon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethephon 15Jan2009 2009 doi:10.2903/j.efsa.2009.174r
+Ethephon 240-718-3 16672-87-0 single chemical entity Component is a metabolite of the substance 2-hydroxyethylphosphonic acid 245-370-6 22987-21-9 2-hydroxyethylphosphonic acid 2-Hydroxyethylphosphonic acid C2H7O4P C(CP(=O)(O)O)O InChI=1S/C2H7O4P/c3-1-2-7(4,5)6/h3H,1-2H2,(H2,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Negative no information RMS: The Netherlands Ethephon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethephon 15Jan2009 2009 doi:10.2903/j.efsa.2009.174r
+Ethephon 240-718-3 16672-87-0 single chemical entity Component is a metabolite of the substance 2-hydroxyethylphosphonic acid 245-370-6 22987-21-9 2-hydroxyethylphosphonic acid 2-Hydroxyethylphosphonic acid C2H7O4P C(CP(=O)(O)O)O InChI=1S/C2H7O4P/c3-1-2-7(4,5)6/h3H,1-2H2,(H2,4,5,6) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative no information RMS: The Netherlands Ethephon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethephon 15Jan2009 2009 doi:10.2903/j.efsa.2009.174r
+Ethephon 240-718-3 16672-87-0 single chemical entity Component is a metabolite of the substance 2-hydroxyethylphosphonic acid 245-370-6 22987-21-9 2-hydroxyethylphosphonic acid 2-Hydroxyethylphosphonic acid C2H7O4P C(CP(=O)(O)O)O InChI=1S/C2H7O4P/c3-1-2-7(4,5)6/h3H,1-2H2,(H2,4,5,6) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported no data without Negative RMS: The Netherlands Ethephon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethephon 15Jan2009 2009 doi:10.2903/j.efsa.2009.174r
+Ethephon 240-718-3 16672-87-0 single chemical entity Component is a metabolite of the substance 2-hydroxyethylphosphonic acid 245-370-6 22987-21-9 2-hydroxyethylphosphonic acid 2-Hydroxyethylphosphonic acid C2H7O4P C(CP(=O)(O)O)O InChI=1S/C2H7O4P/c3-1-2-7(4,5)6/h3H,1-2H2,(H2,4,5,6) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported no data with Negative RMS: The Netherlands Ethephon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethephon 15Jan2009 2009 doi:10.2903/j.efsa.2009.174r
+S-abscisic acid 244-319-5 21293-29-8 single chemical entity Component is identical to the substance S-abscisic acid 244-319-5 21293-29-8 (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid Not in list C15H20O4 CC1=CC(=O)CC([C@]1(/C=C/C(=C\C(=O)O)/C)O)(C)C InChI=1S/C15H20O4/c1-10(7-13(17)18)5-6-15(19)11(2)8-12(16)9-14(15,3)4/h5-8,19H,9H2,1-4H3,(H,17,18)/b6-5+,10-7-/t15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands S-abscisic acid 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance S-abscisic acid. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3341
+S-abscisic acid 244-319-5 21293-29-8 single chemical entity Component is identical to the substance S-abscisic acid 244-319-5 21293-29-8 (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid Not in list C15H20O4 CC1=CC(=O)CC([C@]1(/C=C/C(=C\C(=O)O)/C)O)(C)C InChI=1S/C15H20O4/c1-10(7-13(17)18)5-6-15(19)11(2)8-12(16)9-14(15,3)4/h5-8,19H,9H2,1-4H3,(H,17,18)/b6-5+,10-7-/t15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands S-abscisic acid 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance S-abscisic acid. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3341
+S-abscisic acid 244-319-5 21293-29-8 single chemical entity Component is identical to the substance S-abscisic acid 244-319-5 21293-29-8 (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid Not in list C15H20O4 CC1=CC(=O)CC([C@]1(/C=C/C(=C\C(=O)O)/C)O)(C)C InChI=1S/C15H20O4/c1-10(7-13(17)18)5-6-15(19)11(2)8-12(16)9-14(15,3)4/h5-8,19H,9H2,1-4H3,(H,17,18)/b6-5+,10-7-/t15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands S-abscisic acid 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance S-abscisic acid. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3341
+S-abscisic acid 244-319-5 21293-29-8 single chemical entity Component is identical to the substance S-abscisic acid 244-319-5 21293-29-8 (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid Not in list C15H20O4 CC1=CC(=O)CC([C@]1(/C=C/C(=C\C(=O)O)/C)O)(C)C InChI=1S/C15H20O4/c1-10(7-13(17)18)5-6-15(19)11(2)8-12(16)9-14(15,3)4/h5-8,19H,9H2,1-4H3,(H,17,18)/b6-5+,10-7-/t15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands S-abscisic acid 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance S-abscisic acid. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3341
+S-abscisic acid 244-319-5 21293-29-8 single chemical entity Component is identical to the substance S-abscisic acid 244-319-5 21293-29-8 (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid Not in list C15H20O4 CC1=CC(=O)CC([C@]1(/C=C/C(=C\C(=O)O)/C)O)(C)C InChI=1S/C15H20O4/c1-10(7-13(17)18)5-6-15(19)11(2)8-12(16)9-14(15,3)4/h5-8,19H,9H2,1-4H3,(H,17,18)/b6-5+,10-7-/t15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands S-abscisic acid 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance S-abscisic acid. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3341
+S-abscisic acid 244-319-5 21293-29-8 single chemical entity Component is identical to the substance S-abscisic acid 244-319-5 21293-29-8 (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid Not in list C15H20O4 CC1=CC(=O)CC([C@]1(/C=C/C(=C\C(=O)O)/C)O)(C)C InChI=1S/C15H20O4/c1-10(7-13(17)18)5-6-15(19)11(2)8-12(16)9-14(15,3)4/h5-8,19H,9H2,1-4H3,(H,17,18)/b6-5+,10-7-/t15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands S-abscisic acid 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance S-abscisic acid. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3341
+S-abscisic acid 244-319-5 21293-29-8 single chemical entity Component is identical to the substance S-abscisic acid 244-319-5 21293-29-8 (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid Not in list C15H20O4 CC1=CC(=O)CC([C@]1(/C=C/C(=C\C(=O)O)/C)O)(C)C InChI=1S/C15H20O4/c1-10(7-13(17)18)5-6-15(19)11(2)8-12(16)9-14(15,3)4/h5-8,19H,9H2,1-4H3,(H,17,18)/b6-5+,10-7-/t15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands S-abscisic acid 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance S-abscisic acid. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3341
+S-abscisic acid 244-319-5 21293-29-8 single chemical entity Component is identical to the substance S-abscisic acid 244-319-5 21293-29-8 (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid Not in list C15H20O4 CC1=CC(=O)CC([C@]1(/C=C/C(=C\C(=O)O)/C)O)(C)C InChI=1S/C15H20O4/c1-10(7-13(17)18)5-6-15(19)11(2)8-12(16)9-14(15,3)4/h5-8,19H,9H2,1-4H3,(H,17,18)/b6-5+,10-7-/t15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands S-abscisic acid 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance S-abscisic acid. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3341
+S-abscisic acid 244-319-5 21293-29-8 single chemical entity Component is identical to the substance S-abscisic acid 244-319-5 21293-29-8 (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid Not in list C15H20O4 CC1=CC(=O)CC([C@]1(/C=C/C(=C\C(=O)O)/C)O)(C)C InChI=1S/C15H20O4/c1-10(7-13(17)18)5-6-15(19)11(2)8-12(16)9-14(15,3)4/h5-8,19H,9H2,1-4H3,(H,17,18)/b6-5+,10-7-/t15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands S-abscisic acid 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance S-abscisic acid. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3341
+S-abscisic acid 244-319-5 21293-29-8 single chemical entity Component is identical to the substance S-abscisic acid 244-319-5 21293-29-8 (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid Not in list C15H20O4 CC1=CC(=O)CC([C@]1(/C=C/C(=C\C(=O)O)/C)O)(C)C InChI=1S/C15H20O4/c1-10(7-13(17)18)5-6-15(19)11(2)8-12(16)9-14(15,3)4/h5-8,19H,9H2,1-4H3,(H,17,18)/b6-5+,10-7-/t15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands S-abscisic acid 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance S-abscisic acid. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3341
+S-abscisic acid 244-319-5 21293-29-8 single chemical entity Component is identical to the substance S-abscisic acid 244-319-5 21293-29-8 (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid Not in list C15H20O4 CC1=CC(=O)CC([C@]1(/C=C/C(=C\C(=O)O)/C)O)(C)C InChI=1S/C15H20O4/c1-10(7-13(17)18)5-6-15(19)11(2)8-12(16)9-14(15,3)4/h5-8,19H,9H2,1-4H3,(H,17,18)/b6-5+,10-7-/t15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: The Netherlands S-abscisic acid 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance S-abscisic acid. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3341
+S-abscisic acid 244-319-5 21293-29-8 single chemical entity Component is identical to the substance S-abscisic acid 244-319-5 21293-29-8 (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid Not in list C15H20O4 CC1=CC(=O)CC([C@]1(/C=C/C(=C\C(=O)O)/C)O)(C)C InChI=1S/C15H20O4/c1-10(7-13(17)18)5-6-15(19)11(2)8-12(16)9-14(15,3)4/h5-8,19H,9H2,1-4H3,(H,17,18)/b6-5+,10-7-/t15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: The Netherlands S-abscisic acid 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance S-abscisic acid. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3341
+S-abscisic acid 244-319-5 21293-29-8 single chemical entity Component is identical to the substance S-abscisic acid 244-319-5 21293-29-8 (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid Not in list C15H20O4 CC1=CC(=O)CC([C@]1(/C=C/C(=C\C(=O)O)/C)O)(C)C InChI=1S/C15H20O4/c1-10(7-13(17)18)5-6-15(19)11(2)8-12(16)9-14(15,3)4/h5-8,19H,9H2,1-4H3,(H,17,18)/b6-5+,10-7-/t15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: The Netherlands S-abscisic acid 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance S-abscisic acid. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3341
+S-abscisic acid 244-319-5 21293-29-8 single chemical entity Component is identical to the substance S-abscisic acid 244-319-5 21293-29-8 (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid Not in list C15H20O4 CC1=CC(=O)CC([C@]1(/C=C/C(=C\C(=O)O)/C)O)(C)C InChI=1S/C15H20O4/c1-10(7-13(17)18)5-6-15(19)11(2)8-12(16)9-14(15,3)4/h5-8,19H,9H2,1-4H3,(H,17,18)/b6-5+,10-7-/t15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: The Netherlands S-abscisic acid 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance S-abscisic acid. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3341
+S-abscisic acid 244-319-5 21293-29-8 single chemical entity Component is identical to the substance S-abscisic acid 244-319-5 21293-29-8 (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid Not in list C15H20O4 CC1=CC(=O)CC([C@]1(/C=C/C(=C\C(=O)O)/C)O)(C)C InChI=1S/C15H20O4/c1-10(7-13(17)18)5-6-15(19)11(2)8-12(16)9-14(15,3)4/h5-8,19H,9H2,1-4H3,(H,17,18)/b6-5+,10-7-/t15-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The Netherlands S-abscisic acid 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance S-abscisic acid. 29Aug2013 2013 doi:10.2903/j.efsa.2013.3341
+Sodium hypochlorite 231-668-3 7681-52-9 single chemical entity Component is identical to the substance Sodium hypochlorite 231-668-3 7681-52-9 Sodium;hypochlorite Not in list ClNaO [O-]Cl.[Na+] InChI=1S/ClO.Na/c1-2;/q-1;+1 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: The Netherlands Sodium hypochlorite 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sodium hypochlorite 02Jul2012 2012 doi:10.2903/j.efsa.2012.2796
+Sodium hypochlorite 231-668-3 7681-52-9 single chemical entity Component is identical to the substance Sodium hypochlorite 231-668-3 7681-52-9 Sodium;hypochlorite Not in list ClNaO [O-]Cl.[Na+] InChI=1S/ClO.Na/c1-2;/q-1;+1 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: The Netherlands Sodium hypochlorite 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sodium hypochlorite 02Jul2012 2012 doi:10.2903/j.efsa.2012.2796
+Sodium hypochlorite 231-668-3 7681-52-9 single chemical entity Component is identical to the substance Sodium hypochlorite 231-668-3 7681-52-9 Sodium;hypochlorite Not in list ClNaO [O-]Cl.[Na+] InChI=1S/ClO.Na/c1-2;/q-1;+1 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA1530 Not reported no data without Positive RMS: The Netherlands Sodium hypochlorite 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sodium hypochlorite 02Jul2012 2012 doi:10.2903/j.efsa.2012.2796
+Sodium hypochlorite 231-668-3 7681-52-9 single chemical entity Component is identical to the substance Sodium hypochlorite 231-668-3 7681-52-9 Sodium;hypochlorite Not in list ClNaO [O-]Cl.[Na+] InChI=1S/ClO.Na/c1-2;/q-1;+1 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported no data without Negative RMS: The Netherlands Sodium hypochlorite 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sodium hypochlorite 02Jul2012 2012 doi:10.2903/j.efsa.2012.2796
+Sodium hypochlorite 231-668-3 7681-52-9 single chemical entity Component is identical to the substance Sodium hypochlorite 231-668-3 7681-52-9 Sodium;hypochlorite Not in list ClNaO [O-]Cl.[Na+] InChI=1S/ClO.Na/c1-2;/q-1;+1 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported no data with Negative RMS: The Netherlands Sodium hypochlorite 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sodium hypochlorite 02Jul2012 2012 doi:10.2903/j.efsa.2012.2796
+Sodium hypochlorite 231-668-3 7681-52-9 single chemical entity Component is identical to the substance Sodium hypochlorite 231-668-3 7681-52-9 Sodium;hypochlorite Not in list ClNaO [O-]Cl.[Na+] InChI=1S/ClO.Na/c1-2;/q-1;+1 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: The Netherlands Sodium hypochlorite 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sodium hypochlorite 02Jul2012 2012 doi:10.2903/j.efsa.2012.2796
+Sodium hypochlorite 231-668-3 7681-52-9 single chemical entity Component is identical to the substance Sodium hypochlorite 231-668-3 7681-52-9 Sodium;hypochlorite Not in list ClNaO [O-]Cl.[Na+] InChI=1S/ClO.Na/c1-2;/q-1;+1 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: The Netherlands Sodium hypochlorite 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sodium hypochlorite 02Jul2012 2012 doi:10.2903/j.efsa.2012.2796
+Sodium hypochlorite 231-668-3 7681-52-9 single chemical entity Component is identical to the substance Sodium hypochlorite 231-668-3 7681-52-9 Sodium;hypochlorite Not in list ClNaO [O-]Cl.[Na+] InChI=1S/ClO.Na/c1-2;/q-1;+1 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 Male/Female oral: feed 5.0000000000 D no data not applicable Negative no evidence RMS: The Netherlands Sodium hypochlorite 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sodium hypochlorite 02Jul2012 2012 doi:10.2903/j.efsa.2012.2796
+Sodium hypochlorite 231-668-3 7681-52-9 single chemical entity Component is identical to the substance Sodium hypochlorite 231-668-3 7681-52-9 Sodium;hypochlorite Not in list ClNaO [O-]Cl.[Na+] InChI=1S/ClO.Na/c1-2;/q-1;+1 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Not reported No data intraperitoneal 24.0000000000 h no data not applicable Negative direct evidence-cytotoxicity$indirect evidence-systemic toxicity RMS: The Netherlands Sodium hypochlorite 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sodium hypochlorite 02Jul2012 2012 doi:10.2903/j.efsa.2012.2796
+Sodium hypochlorite 231-668-3 7681-52-9 single chemical entity Component is identical to the substance Sodium hypochlorite 231-668-3 7681-52-9 Sodium;hypochlorite Not in list ClNaO [O-]Cl.[Na+] InChI=1S/ClO.Na/c1-2;/q-1;+1 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: The Netherlands Sodium hypochlorite 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sodium hypochlorite 02Jul2012 2012 doi:10.2903/j.efsa.2012.2796
+Sodium hypochlorite 231-668-3 7681-52-9 single chemical entity Component is identical to the substance Sodium hypochlorite 231-668-3 7681-52-9 Sodium;hypochlorite Not in list ClNaO [O-]Cl.[Na+] InChI=1S/ClO.Na/c1-2;/q-1;+1 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA94 Not reported no data with Negative RMS: The Netherlands Sodium hypochlorite 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sodium hypochlorite 02Jul2012 2012 doi:10.2903/j.efsa.2012.2796
+Sodium hypochlorite 231-668-3 7681-52-9 single chemical entity Component is identical to the substance Sodium hypochlorite 231-668-3 7681-52-9 Sodium;hypochlorite Not in list ClNaO [O-]Cl.[Na+] InChI=1S/ClO.Na/c1-2;/q-1;+1 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA92 Not reported no data without Negative RMS: The Netherlands Sodium hypochlorite 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sodium hypochlorite 02Jul2012 2012 doi:10.2903/j.efsa.2012.2796
+Sodium hypochlorite 231-668-3 7681-52-9 single chemical entity Component is identical to the substance Sodium hypochlorite 231-668-3 7681-52-9 Sodium;hypochlorite Not in list ClNaO [O-]Cl.[Na+] InChI=1S/ClO.Na/c1-2;/q-1;+1 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: The Netherlands Sodium hypochlorite 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sodium hypochlorite 02Jul2012 2012 doi:10.2903/j.efsa.2012.2796
+Sodium hypochlorite 231-668-3 7681-52-9 single chemical entity Component is identical to the substance Sodium hypochlorite 231-668-3 7681-52-9 Sodium;hypochlorite Not in list ClNaO [O-]Cl.[Na+] InChI=1S/ClO.Na/c1-2;/q-1;+1 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: The Netherlands Sodium hypochlorite 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sodium hypochlorite 02Jul2012 2012 doi:10.2903/j.efsa.2012.2796
+Sodium hypochlorite 231-668-3 7681-52-9 single chemical entity Component is identical to the substance Sodium hypochlorite 231-668-3 7681-52-9 Sodium;hypochlorite Not in list ClNaO [O-]Cl.[Na+] InChI=1S/ClO.Na/c1-2;/q-1;+1 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: The Netherlands Sodium hypochlorite 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sodium hypochlorite 02Jul2012 2012 doi:10.2903/j.efsa.2012.2796
+Sodium hypochlorite 231-668-3 7681-52-9 single chemical entity Component is identical to the substance Sodium hypochlorite 231-668-3 7681-52-9 Sodium;hypochlorite Not in list ClNaO [O-]Cl.[Na+] InChI=1S/ClO.Na/c1-2;/q-1;+1 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA92 Not reported no data with Negative RMS: The Netherlands Sodium hypochlorite 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sodium hypochlorite 02Jul2012 2012 doi:10.2903/j.efsa.2012.2796
+Sodium hypochlorite 231-668-3 7681-52-9 single chemical entity Component is identical to the substance Sodium hypochlorite 231-668-3 7681-52-9 Sodium;hypochlorite Not in list ClNaO [O-]Cl.[Na+] InChI=1S/ClO.Na/c1-2;/q-1;+1 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: The Netherlands Sodium hypochlorite 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sodium hypochlorite 02Jul2012 2012 doi:10.2903/j.efsa.2012.2796
+Sodium hypochlorite 231-668-3 7681-52-9 single chemical entity Component is identical to the substance Sodium hypochlorite 231-668-3 7681-52-9 Sodium;hypochlorite Not in list ClNaO [O-]Cl.[Na+] InChI=1S/ClO.Na/c1-2;/q-1;+1 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Positive RMS: The Netherlands Sodium hypochlorite 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sodium hypochlorite 02Jul2012 2012 doi:10.2903/j.efsa.2012.2796
+Sodium hypochlorite 231-668-3 7681-52-9 single chemical entity Component is identical to the substance Sodium hypochlorite 231-668-3 7681-52-9 Sodium;hypochlorite Not in list ClNaO [O-]Cl.[Na+] InChI=1S/ClO.Na/c1-2;/q-1;+1 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: The Netherlands Sodium hypochlorite 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sodium hypochlorite 02Jul2012 2012 doi:10.2903/j.efsa.2012.2796
+Sodium hypochlorite 231-668-3 7681-52-9 single chemical entity Component is identical to the substance Sodium hypochlorite 231-668-3 7681-52-9 Sodium;hypochlorite Not in list ClNaO [O-]Cl.[Na+] InChI=1S/ClO.Na/c1-2;/q-1;+1 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: The Netherlands Sodium hypochlorite 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sodium hypochlorite 02Jul2012 2012 doi:10.2903/j.efsa.2012.2796
+Sodium hypochlorite 231-668-3 7681-52-9 single chemical entity Component is identical to the substance Sodium hypochlorite 231-668-3 7681-52-9 Sodium;hypochlorite Not in list ClNaO [O-]Cl.[Na+] InChI=1S/ClO.Na/c1-2;/q-1;+1 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA94 Not reported no data without Negative RMS: The Netherlands Sodium hypochlorite 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sodium hypochlorite 02Jul2012 2012 doi:10.2903/j.efsa.2012.2796
+Sodium hypochlorite 231-668-3 7681-52-9 single chemical entity Component is identical to the substance Sodium hypochlorite 231-668-3 7681-52-9 Sodium;hypochlorite Not in list ClNaO [O-]Cl.[Na+] InChI=1S/ClO.Na/c1-2;/q-1;+1 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) Not reported Not reported no data with Negative RMS: The Netherlands Sodium hypochlorite 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sodium hypochlorite 02Jul2012 2012 doi:10.2903/j.efsa.2012.2796
+Sodium hypochlorite 231-668-3 7681-52-9 single chemical entity Component is identical to the substance Sodium hypochlorite 231-668-3 7681-52-9 Sodium;hypochlorite Not in list ClNaO [O-]Cl.[Na+] InChI=1S/ClO.Na/c1-2;/q-1;+1 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) Not reported Not reported no data without Negative RMS: The Netherlands Sodium hypochlorite 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sodium hypochlorite 02Jul2012 2012 doi:10.2903/j.efsa.2012.2796
+Sodium hypochlorite 231-668-3 7681-52-9 single chemical entity Component is identical to the substance Sodium hypochlorite 231-668-3 7681-52-9 Sodium;hypochlorite Not in list ClNaO [O-]Cl.[Na+] InChI=1S/ClO.Na/c1-2;/q-1;+1 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) fibroblast Not reported no data no data Negative RMS: The Netherlands Sodium hypochlorite 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sodium hypochlorite 02Jul2012 2012 doi:10.2903/j.efsa.2012.2796
+Sulfuryl fluoride 220-281-5 2699-79-8 single chemical entity Component is identical to the substance Sulfuryl fluoride 220-281-5 2699-79-8 Sulfuryl difluoride Sulfuryl fluoride F2O2S O=S(=O)(F)F InChI=1S/F2O2S/c1-5(2,3)4 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The United Kingdom Sulfuryl Fluoride 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfuryl fluoride 14Jan2010 2010 doi:10.2903/j.efsa.2010.1441
+Sulfuryl fluoride 220-281-5 2699-79-8 single chemical entity Component is identical to the substance Sulfuryl fluoride 220-281-5 2699-79-8 Sulfuryl difluoride Sulfuryl fluoride F2O2S O=S(=O)(F)F InChI=1S/F2O2S/c1-5(2,3)4 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The United Kingdom Sulfuryl Fluoride 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfuryl fluoride 14Jan2010 2010 doi:10.2903/j.efsa.2010.1441
+Sulfuryl fluoride 220-281-5 2699-79-8 single chemical entity Component is identical to the substance Sulfuryl fluoride 220-281-5 2699-79-8 Sulfuryl difluoride Sulfuryl fluoride F2O2S O=S(=O)(F)F InChI=1S/F2O2S/c1-5(2,3)4 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The United Kingdom Sulfuryl Fluoride 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfuryl fluoride 14Jan2010 2010 doi:10.2903/j.efsa.2010.1441
+Sulfuryl fluoride 220-281-5 2699-79-8 single chemical entity Component is identical to the substance Sulfuryl fluoride 220-281-5 2699-79-8 Sulfuryl difluoride Sulfuryl fluoride F2O2S O=S(=O)(F)F InChI=1S/F2O2S/c1-5(2,3)4 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The United Kingdom Sulfuryl Fluoride 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfuryl fluoride 14Jan2010 2010 doi:10.2903/j.efsa.2010.1441
+Sulfuryl fluoride 220-281-5 2699-79-8 single chemical entity Component is identical to the substance Sulfuryl fluoride 220-281-5 2699-79-8 Sulfuryl difluoride Sulfuryl fluoride F2O2S O=S(=O)(F)F InChI=1S/F2O2S/c1-5(2,3)4 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The United Kingdom Sulfuryl Fluoride 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfuryl fluoride 14Jan2010 2010 doi:10.2903/j.efsa.2010.1441
+Sulfuryl fluoride 220-281-5 2699-79-8 single chemical entity Component is identical to the substance Sulfuryl fluoride 220-281-5 2699-79-8 Sulfuryl difluoride Sulfuryl fluoride F2O2S O=S(=O)(F)F InChI=1S/F2O2S/c1-5(2,3)4 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The United Kingdom Sulfuryl Fluoride 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfuryl fluoride 14Jan2010 2010 doi:10.2903/j.efsa.2010.1441
+Sulfuryl fluoride 220-281-5 2699-79-8 single chemical entity Component is identical to the substance Sulfuryl fluoride 220-281-5 2699-79-8 Sulfuryl difluoride Sulfuryl fluoride F2O2S O=S(=O)(F)F InChI=1S/F2O2S/c1-5(2,3)4 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The United Kingdom Sulfuryl Fluoride 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfuryl fluoride 14Jan2010 2010 doi:10.2903/j.efsa.2010.1441
+Sulfuryl fluoride 220-281-5 2699-79-8 single chemical entity Component is identical to the substance Sulfuryl fluoride 220-281-5 2699-79-8 Sulfuryl difluoride Sulfuryl fluoride F2O2S O=S(=O)(F)F InChI=1S/F2O2S/c1-5(2,3)4 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The United Kingdom Sulfuryl Fluoride 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfuryl fluoride 14Jan2010 2010 doi:10.2903/j.efsa.2010.1441
+Sulfuryl fluoride 220-281-5 2699-79-8 single chemical entity Component is identical to the substance Sulfuryl fluoride 220-281-5 2699-79-8 Sulfuryl difluoride Sulfuryl fluoride F2O2S O=S(=O)(F)F InChI=1S/F2O2S/c1-5(2,3)4 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: The United Kingdom Sulfuryl Fluoride 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfuryl fluoride 14Jan2010 2010 doi:10.2903/j.efsa.2010.1441
+Sulfuryl fluoride 220-281-5 2699-79-8 single chemical entity Component is identical to the substance Sulfuryl fluoride 220-281-5 2699-79-8 Sulfuryl difluoride Sulfuryl fluoride F2O2S O=S(=O)(F)F InChI=1S/F2O2S/c1-5(2,3)4 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: The United Kingdom Sulfuryl Fluoride 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfuryl fluoride 14Jan2010 2010 doi:10.2903/j.efsa.2010.1441
+Sulfuryl fluoride 220-281-5 2699-79-8 single chemical entity Component is identical to the substance Sulfuryl fluoride 220-281-5 2699-79-8 Sulfuryl difluoride Sulfuryl fluoride F2O2S O=S(=O)(F)F InChI=1S/F2O2S/c1-5(2,3)4 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Rat (as animal) lymphocytes Not reported yes with Positive RMS: The United Kingdom Sulfuryl Fluoride 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfuryl fluoride 14Jan2010 2010 doi:10.2903/j.efsa.2010.1441
+Sulfuryl fluoride 220-281-5 2699-79-8 single chemical entity Component is identical to the substance Sulfuryl fluoride 220-281-5 2699-79-8 Sulfuryl difluoride Sulfuryl fluoride F2O2S O=S(=O)(F)F InChI=1S/F2O2S/c1-5(2,3)4 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Rat (as animal) lymphocytes Not reported yes without Positive RMS: The United Kingdom Sulfuryl Fluoride 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfuryl fluoride 14Jan2010 2010 doi:10.2903/j.efsa.2010.1441
+Sulfuryl fluoride 220-281-5 2699-79-8 single chemical entity Component is identical to the substance Sulfuryl fluoride 220-281-5 2699-79-8 Sulfuryl difluoride Sulfuryl fluoride F2O2S O=S(=O)(F)F InChI=1S/F2O2S/c1-5(2,3)4 inorganic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes without Negative RMS: The United Kingdom Sulfuryl Fluoride 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfuryl fluoride 14Jan2010 2010 doi:10.2903/j.efsa.2010.1441
+Sulfuryl fluoride 220-281-5 2699-79-8 single chemical entity Component is identical to the substance Sulfuryl fluoride 220-281-5 2699-79-8 Sulfuryl difluoride Sulfuryl fluoride F2O2S O=S(=O)(F)F InChI=1S/F2O2S/c1-5(2,3)4 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Positive no information RMS: The United Kingdom Sulfuryl Fluoride 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfuryl fluoride 14Jan2010 2010 doi:10.2903/j.efsa.2010.1441
+Sulfuryl fluoride 220-281-5 2699-79-8 single chemical entity Component is identical to the substance Sulfuryl fluoride 220-281-5 2699-79-8 Sulfuryl difluoride Sulfuryl fluoride F2O2S O=S(=O)(F)F InChI=1S/F2O2S/c1-5(2,3)4 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Positive no information RMS: The United Kingdom Sulfuryl Fluoride 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfuryl fluoride 14Jan2010 2010 doi:10.2903/j.efsa.2010.1441
+Sulfuryl fluoride 220-281-5 2699-79-8 single chemical entity Component is identical to the substance Sulfuryl fluoride 220-281-5 2699-79-8 Sulfuryl difluoride Sulfuryl fluoride F2O2S O=S(=O)(F)F InChI=1S/F2O2S/c1-5(2,3)4 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female inhalation: unspecified 72.0000000000 h yes not applicable Negative no evidence RMS: The United Kingdom Sulfuryl Fluoride 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfuryl fluoride 14Jan2010 2010 doi:10.2903/j.efsa.2010.1441
+Sulfuryl fluoride 220-281-5 2699-79-8 single chemical entity Component is identical to the substance Sulfuryl fluoride 220-281-5 2699-79-8 Sulfuryl difluoride Sulfuryl fluoride F2O2S O=S(=O)(F)F InChI=1S/F2O2S/c1-5(2,3)4 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female inhalation: unspecified 48.0000000000 h yes not applicable Negative no evidence RMS: The United Kingdom Sulfuryl Fluoride 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfuryl fluoride 14Jan2010 2010 doi:10.2903/j.efsa.2010.1441
+Sulfuryl fluoride 220-281-5 2699-79-8 single chemical entity Component is identical to the substance Sulfuryl fluoride 220-281-5 2699-79-8 Sulfuryl difluoride Sulfuryl fluoride F2O2S O=S(=O)(F)F InChI=1S/F2O2S/c1-5(2,3)4 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female inhalation: unspecified 24.0000000000 h yes not applicable Negative no evidence RMS: The United Kingdom Sulfuryl Fluoride 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfuryl fluoride 14Jan2010 2010 doi:10.2903/j.efsa.2010.1441
+Sulcotrione 99105-77-8 single chemical entity Component is identical to the substance Sulcotrione 99105-77-8 2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione Sulcotrione C14H13ClO5S O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is identical to the substance Sulcotrione 99105-77-8 2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione Sulcotrione C14H13ClO5S O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is identical to the substance Sulcotrione 99105-77-8 2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione Sulcotrione C14H13ClO5S O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is identical to the substance Sulcotrione 99105-77-8 2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione Sulcotrione C14H13ClO5S O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is identical to the substance Sulcotrione 99105-77-8 2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione Sulcotrione C14H13ClO5S O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Positive RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is identical to the substance Sulcotrione 99105-77-8 2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione Sulcotrione C14H13ClO5S O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Positive RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is identical to the substance Sulcotrione 99105-77-8 2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione Sulcotrione C14H13ClO5S O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Positive RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is identical to the substance Sulcotrione 99105-77-8 2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione Sulcotrione C14H13ClO5S O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Positive RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is identical to the substance Sulcotrione 99105-77-8 2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione Sulcotrione C14H13ClO5S O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Ambiguous RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is identical to the substance Sulcotrione 99105-77-8 2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione Sulcotrione C14H13ClO5S O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Positive RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is identical to the substance Sulcotrione 99105-77-8 2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione Sulcotrione C14H13ClO5S O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Positive RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is identical to the substance Sulcotrione 99105-77-8 2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione Sulcotrione C14H13ClO5S O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle with Negative RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is identical to the substance Sulcotrione 99105-77-8 2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione Sulcotrione C14H13ClO5S O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle without Negative RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is identical to the substance Sulcotrione 99105-77-8 2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione Sulcotrione C14H13ClO5S O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is identical to the substance Sulcotrione 99105-77-8 2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione Sulcotrione C14H13ClO5S O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Positive RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is identical to the substance Sulcotrione 99105-77-8 2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione Sulcotrione C14H13ClO5S O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Positive RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is identical to the substance Sulcotrione 99105-77-8 2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione Sulcotrione C14H13ClO5S O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Positive RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is identical to the substance Sulcotrione 99105-77-8 2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione Sulcotrione C14H13ClO5S O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is identical to the substance Sulcotrione 99105-77-8 2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione Sulcotrione C14H13ClO5S O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is identical to the substance Sulcotrione 99105-77-8 2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione Sulcotrione C14H13ClO5S O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is identical to the substance Sulcotrione 99105-77-8 2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione Sulcotrione C14H13ClO5S O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is identical to the substance Sulcotrione 99105-77-8 2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione Sulcotrione C14H13ClO5S O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Positive RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is identical to the substance Sulcotrione 99105-77-8 2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione Sulcotrione C14H13ClO5S O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is identical to the substance Sulcotrione 99105-77-8 2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione Sulcotrione C14H13ClO5S O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is identical to the substance Sulcotrione 99105-77-8 2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione Sulcotrione C14H13ClO5S O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is identical to the substance Sulcotrione 99105-77-8 2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione Sulcotrione C14H13ClO5S O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is identical to the substance Sulcotrione 99105-77-8 2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione Sulcotrione C14H13ClO5S O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is identical to the substance Sulcotrione 99105-77-8 2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione Sulcotrione C14H13ClO5S O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is identical to the substance Sulcotrione 99105-77-8 2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione Sulcotrione C14H13ClO5S O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is identical to the substance Sulcotrione 99105-77-8 2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione Sulcotrione C14H13ClO5S O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is identical to the substance Sulcotrione 99105-77-8 2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione Sulcotrione C14H13ClO5S O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is identical to the substance Sulcotrione 99105-77-8 2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione Sulcotrione C14H13ClO5S O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is identical to the substance Sulcotrione 99105-77-8 2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione Sulcotrione C14H13ClO5S O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is identical to the substance Sulcotrione 99105-77-8 2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione Sulcotrione C14H13ClO5S O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is identical to the substance Sulcotrione 99105-77-8 2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione Sulcotrione C14H13ClO5S O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is identical to the substance Sulcotrione 99105-77-8 2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione Sulcotrione C14H13ClO5S O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is identical to the substance Sulcotrione 99105-77-8 2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione Sulcotrione C14H13ClO5S O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is identical to the substance Sulcotrione 99105-77-8 2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione Sulcotrione C14H13ClO5S O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is identical to the substance Sulcotrione 99105-77-8 2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione Sulcotrione C14H13ClO5S O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is identical to the substance Sulcotrione 99105-77-8 2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione Sulcotrione C14H13ClO5S O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Positive no information RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is identical to the substance Sulcotrione 99105-77-8 2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione Sulcotrione C14H13ClO5S O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is identical to the substance Sulcotrione 99105-77-8 2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione Sulcotrione C14H13ClO5S O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Positive RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is identical to the substance Sulcotrione 99105-77-8 2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione Sulcotrione C14H13ClO5S O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes with Negative RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is identical to the substance Sulcotrione 99105-77-8 2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione Sulcotrione C14H13ClO5S O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes without Negative RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is identical to the substance Sulcotrione 99105-77-8 2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione Sulcotrione C14H13ClO5S O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) C57BL 10 Male oral: gavage 24.0000000000 h yes not applicable Negative no evidence RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is identical to the substance Sulcotrione 99105-77-8 2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione Sulcotrione C14H13ClO5S O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) C57BL 10 Male oral: gavage 72.0000000000 h yes not applicable Positive direct evidence-cytotoxicity RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is identical to the substance Sulcotrione 99105-77-8 2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione Sulcotrione C14H13ClO5S O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) C57BL 10 Male oral: gavage 48.0000000000 h yes not applicable Positive no evidence RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is identical to the substance Sulcotrione 99105-77-8 2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione Sulcotrione C14H13ClO5S O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 48.0000000000 h yes not applicable Negative indirect evidence-systemic toxicity RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is identical to the substance Sulcotrione 99105-77-8 2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione Sulcotrione C14H13ClO5S O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes not applicable Negative indirect evidence-systemic toxicity RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is identical to the substance Sulcotrione 99105-77-8 2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione Sulcotrione C14H13ClO5S O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 72.0000000000 h yes not applicable Negative indirect evidence-systemic toxicity RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is identical to the substance Sulcotrione 99105-77-8 2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione Sulcotrione C14H13ClO5S O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 48.0000000000 h yes not applicable Negative no evidence RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is identical to the substance Sulcotrione 99105-77-8 2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione Sulcotrione C14H13ClO5S O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes not applicable Negative no evidence RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is identical to the substance Sulcotrione 99105-77-8 2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione Sulcotrione C14H13ClO5S O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 72.0000000000 h yes not applicable Negative no evidence RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is identical to the substance Sulcotrione 99105-77-8 2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione Sulcotrione C14H13ClO5S O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo Equivalent or similar to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) Yes Acceptable Rat (as animal) Sprague-Dawley 5 Male Not reported 12.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is identical to the substance Sulcotrione 99105-77-8 2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione Sulcotrione C14H13ClO5S O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo Equivalent or similar to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) Yes Acceptable Rat (as animal) Sprague-Dawley 5 Male Not reported 4.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is a metabolite of the substance 2-Chloro-4-(methylsulfonyl)-benzoic acid 406-520-8 53250-83-2 2-Chloro-4-methylsulfonylbenzoic acid Not in list C8H7ClO4S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)O)Cl InChI=1S/C8H7ClO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,1H3,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is a metabolite of the substance 2-Chloro-4-(methylsulfonyl)-benzoic acid 406-520-8 53250-83-2 2-Chloro-4-methylsulfonylbenzoic acid Not in list C8H7ClO4S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)O)Cl InChI=1S/C8H7ClO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,1H3,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is a metabolite of the substance 2-Chloro-4-(methylsulfonyl)-benzoic acid 406-520-8 53250-83-2 2-Chloro-4-methylsulfonylbenzoic acid Not in list C8H7ClO4S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)O)Cl InChI=1S/C8H7ClO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,1H3,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is a metabolite of the substance 2-Chloro-4-(methylsulfonyl)-benzoic acid 406-520-8 53250-83-2 2-Chloro-4-methylsulfonylbenzoic acid Not in list C8H7ClO4S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)O)Cl InChI=1S/C8H7ClO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,1H3,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is a metabolite of the substance 2-Chloro-4-(methylsulfonyl)-benzoic acid 406-520-8 53250-83-2 2-Chloro-4-methylsulfonylbenzoic acid Not in list C8H7ClO4S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)O)Cl InChI=1S/C8H7ClO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,1H3,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is a metabolite of the substance 2-Chloro-4-(methylsulfonyl)-benzoic acid 406-520-8 53250-83-2 2-Chloro-4-methylsulfonylbenzoic acid Not in list C8H7ClO4S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)O)Cl InChI=1S/C8H7ClO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,1H3,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is a metabolite of the substance 2-Chloro-4-(methylsulfonyl)-benzoic acid 406-520-8 53250-83-2 2-Chloro-4-methylsulfonylbenzoic acid Not in list C8H7ClO4S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)O)Cl InChI=1S/C8H7ClO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,1H3,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is a metabolite of the substance 2-Chloro-4-(methylsulfonyl)-benzoic acid 406-520-8 53250-83-2 2-Chloro-4-methylsulfonylbenzoic acid Not in list C8H7ClO4S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)O)Cl InChI=1S/C8H7ClO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,1H3,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is a metabolite of the substance 2-Chloro-4-(methylsulfonyl)-benzoic acid 406-520-8 53250-83-2 2-Chloro-4-methylsulfonylbenzoic acid Not in list C8H7ClO4S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)O)Cl InChI=1S/C8H7ClO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,1H3,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is a metabolite of the substance 2-Chloro-4-(methylsulfonyl)-benzoic acid 406-520-8 53250-83-2 2-Chloro-4-methylsulfonylbenzoic acid Not in list C8H7ClO4S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)O)Cl InChI=1S/C8H7ClO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,1H3,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is a metabolite of the substance 2-Chloro-4-(methylsulfonyl)-benzoic acid 406-520-8 53250-83-2 2-Chloro-4-methylsulfonylbenzoic acid Not in list C8H7ClO4S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)O)Cl InChI=1S/C8H7ClO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,1H3,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is a metabolite of the substance 2-Chloro-4-(methylsulfonyl)-benzoic acid 406-520-8 53250-83-2 2-Chloro-4-methylsulfonylbenzoic acid Not in list C8H7ClO4S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)O)Cl InChI=1S/C8H7ClO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,1H3,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is a metabolite of the substance 2-Chloro-4-(methylsulfonyl)-benzoic acid 406-520-8 53250-83-2 2-Chloro-4-methylsulfonylbenzoic acid Not in list C8H7ClO4S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)O)Cl InChI=1S/C8H7ClO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,1H3,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is a metabolite of the substance 2-Chloro-4-(methylsulfonyl)-benzoic acid 406-520-8 53250-83-2 2-Chloro-4-methylsulfonylbenzoic acid Not in list C8H7ClO4S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)O)Cl InChI=1S/C8H7ClO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,1H3,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 Not reported no data without Negative RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is a metabolite of the substance 2-Chloro-4-(methylsulfonyl)-benzoic acid 406-520-8 53250-83-2 2-Chloro-4-methylsulfonylbenzoic acid Not in list C8H7ClO4S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)O)Cl InChI=1S/C8H7ClO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,1H3,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is a metabolite of the substance 2-Chloro-4-(methylsulfonyl)-benzoic acid 406-520-8 53250-83-2 2-Chloro-4-methylsulfonylbenzoic acid Not in list C8H7ClO4S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)O)Cl InChI=1S/C8H7ClO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,1H3,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 Not reported no data with Negative RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is a metabolite of the substance 2-Chloro-4-(methylsulfonyl)-benzoic acid 406-520-8 53250-83-2 2-Chloro-4-methylsulfonylbenzoic acid Not in list C8H7ClO4S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)O)Cl InChI=1S/C8H7ClO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,1H3,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is a metabolite of the substance 2-Chloro-4-(methylsulfonyl)-benzoic acid 406-520-8 53250-83-2 2-Chloro-4-methylsulfonylbenzoic acid Not in list C8H7ClO4S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)O)Cl InChI=1S/C8H7ClO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,1H3,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is a metabolite of the substance 2-Chloro-4-(methylsulfonyl)-benzoic acid 406-520-8 53250-83-2 2-Chloro-4-methylsulfonylbenzoic acid Not in list C8H7ClO4S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)O)Cl InChI=1S/C8H7ClO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,1H3,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is a metabolite of the substance 2-Chloro-4-(methylsulfonyl)-benzoic acid 406-520-8 53250-83-2 2-Chloro-4-methylsulfonylbenzoic acid Not in list C8H7ClO4S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)O)Cl InChI=1S/C8H7ClO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,1H3,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is a metabolite of the substance 2-Chloro-4-(methylsulfonyl)-benzoic acid 406-520-8 53250-83-2 2-Chloro-4-methylsulfonylbenzoic acid Not in list C8H7ClO4S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)O)Cl InChI=1S/C8H7ClO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,1H3,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is a metabolite of the substance 2-Chloro-4-(methylsulfonyl)-benzoic acid 406-520-8 53250-83-2 2-Chloro-4-methylsulfonylbenzoic acid Not in list C8H7ClO4S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)O)Cl InChI=1S/C8H7ClO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,1H3,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is a metabolite of the substance 2-Chloro-4-(methylsulfonyl)-benzoic acid 406-520-8 53250-83-2 2-Chloro-4-methylsulfonylbenzoic acid Not in list C8H7ClO4S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)O)Cl InChI=1S/C8H7ClO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,1H3,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data with Negative no information RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is a metabolite of the substance 2-Chloro-4-(methylsulfonyl)-benzoic acid 406-520-8 53250-83-2 2-Chloro-4-methylsulfonylbenzoic acid Not in list C8H7ClO4S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)O)Cl InChI=1S/C8H7ClO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,1H3,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data without Negative no information RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is a metabolite of the substance 2-Chloro-4-(methylsulfonyl)-benzoic acid 406-520-8 53250-83-2 2-Chloro-4-methylsulfonylbenzoic acid Not in list C8H7ClO4S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)O)Cl InChI=1S/C8H7ClO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,1H3,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported no data without Negative RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulcotrione 99105-77-8 single chemical entity Component is a metabolite of the substance 2-Chloro-4-(methylsulfonyl)-benzoic acid 406-520-8 53250-83-2 2-Chloro-4-methylsulfonylbenzoic acid Not in list C8H7ClO4S CS(=O)(=O)C1=CC(=C(C=C1)C(=O)O)Cl InChI=1S/C8H7ClO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,1H3,(H,10,11) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported no data with Negative RMS: Germany Sulcotrione 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione 16Oct2008 2008 doi:10.2903/j.efsa.2008.150r
+Sulfosulfuron 141776-32-1 single chemical entity Component is identical to the substance Sulfosulfuron 141776-32-1 1-(4,6-dimethoxypyrimidin-2-yl)-3-(2-ethylsulfonylimidazo[1,2-a]pyridin-3-ylsulfonyl)urea Sulfosulfuron C16H18N6O7S2 CCS(=O)(=O)C1=C(N2C=CC=CC2=N1)S(=O)(=O)NC(=O)NC3=NC(=CC(=N3)OC)OC InChI=1S/C16H18N6O7S2/c1-4-30(24,25)13-14(22-8-6-5-7-10(22)17-13)31(26,27)21-16(23)20-15-18-11(28-2)9-12(19-15)29-3/h5-9H,4H2,1-3H3,(H2,18,19,20,21,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data no data Negative RMS: Sweden - CoRMS: Ireland Sulfosulfuron (Renewal Assessment Report) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron 14Jul2014 2014 doi:10.2903/j.efsa.2014.3764
+Sulfosulfuron 141776-32-1 single chemical entity Component is identical to the substance Sulfosulfuron 141776-32-1 1-(4,6-dimethoxypyrimidin-2-yl)-3-(2-ethylsulfonylimidazo[1,2-a]pyridin-3-ylsulfonyl)urea Sulfosulfuron C16H18N6O7S2 CCS(=O)(=O)C1=C(N2C=CC=CC2=N1)S(=O)(=O)NC(=O)NC3=NC(=CC(=N3)OC)OC InChI=1S/C16H18N6O7S2/c1-4-30(24,25)13-14(22-8-6-5-7-10(22)17-13)31(26,27)21-16(23)20-15-18-11(28-2)9-12(19-15)29-3/h5-9H,4H2,1-3H3,(H2,18,19,20,21,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data no data Negative RMS: Sweden - CoRMS: Ireland Sulfosulfuron (Renewal Assessment Report) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron 14Jul2014 2014 doi:10.2903/j.efsa.2014.3764
+Sulfosulfuron 141776-32-1 single chemical entity Component is identical to the substance Sulfosulfuron 141776-32-1 1-(4,6-dimethoxypyrimidin-2-yl)-3-(2-ethylsulfonylimidazo[1,2-a]pyridin-3-ylsulfonyl)urea Sulfosulfuron C16H18N6O7S2 CCS(=O)(=O)C1=C(N2C=CC=CC2=N1)S(=O)(=O)NC(=O)NC3=NC(=CC(=N3)OC)OC InChI=1S/C16H18N6O7S2/c1-4-30(24,25)13-14(22-8-6-5-7-10(22)17-13)31(26,27)21-16(23)20-15-18-11(28-2)9-12(19-15)29-3/h5-9H,4H2,1-3H3,(H2,18,19,20,21,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported no data no data Negative RMS: Sweden - CoRMS: Ireland Sulfosulfuron (Renewal Assessment Report) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron 14Jul2014 2014 doi:10.2903/j.efsa.2014.3764
+Sulfosulfuron 141776-32-1 single chemical entity Component is identical to the substance Sulfosulfuron 141776-32-1 1-(4,6-dimethoxypyrimidin-2-yl)-3-(2-ethylsulfonylimidazo[1,2-a]pyridin-3-ylsulfonyl)urea Sulfosulfuron C16H18N6O7S2 CCS(=O)(=O)C1=C(N2C=CC=CC2=N1)S(=O)(=O)NC(=O)NC3=NC(=CC(=N3)OC)OC InChI=1S/C16H18N6O7S2/c1-4-30(24,25)13-14(22-8-6-5-7-10(22)17-13)31(26,27)21-16(23)20-15-18-11(28-2)9-12(19-15)29-3/h5-9H,4H2,1-3H3,(H2,18,19,20,21,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data no data Negative RMS: Sweden - CoRMS: Ireland Sulfosulfuron (Renewal Assessment Report) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron 14Jul2014 2014 doi:10.2903/j.efsa.2014.3764
+Sulfosulfuron 141776-32-1 single chemical entity Component is identical to the substance Sulfosulfuron 141776-32-1 1-(4,6-dimethoxypyrimidin-2-yl)-3-(2-ethylsulfonylimidazo[1,2-a]pyridin-3-ylsulfonyl)urea Sulfosulfuron C16H18N6O7S2 CCS(=O)(=O)C1=C(N2C=CC=CC2=N1)S(=O)(=O)NC(=O)NC3=NC(=CC(=N3)OC)OC InChI=1S/C16H18N6O7S2/c1-4-30(24,25)13-14(22-8-6-5-7-10(22)17-13)31(26,27)21-16(23)20-15-18-11(28-2)9-12(19-15)29-3/h5-9H,4H2,1-3H3,(H2,18,19,20,21,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data no data Negative RMS: Sweden - CoRMS: Ireland Sulfosulfuron (Renewal Assessment Report) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron 14Jul2014 2014 doi:10.2903/j.efsa.2014.3764
+Sulfosulfuron 141776-32-1 single chemical entity Component is identical to the substance Sulfosulfuron 141776-32-1 1-(4,6-dimethoxypyrimidin-2-yl)-3-(2-ethylsulfonylimidazo[1,2-a]pyridin-3-ylsulfonyl)urea Sulfosulfuron C16H18N6O7S2 CCS(=O)(=O)C1=C(N2C=CC=CC2=N1)S(=O)(=O)NC(=O)NC3=NC(=CC(=N3)OC)OC InChI=1S/C16H18N6O7S2/c1-4-30(24,25)13-14(22-8-6-5-7-10(22)17-13)31(26,27)21-16(23)20-15-18-11(28-2)9-12(19-15)29-3/h5-9H,4H2,1-3H3,(H2,18,19,20,21,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported no data without Negative RMS: Sweden - CoRMS: Ireland Sulfosulfuron (Renewal Assessment Report) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron 14Jul2014 2014 doi:10.2903/j.efsa.2014.3764
+Sulfosulfuron 141776-32-1 single chemical entity Component is identical to the substance Sulfosulfuron 141776-32-1 1-(4,6-dimethoxypyrimidin-2-yl)-3-(2-ethylsulfonylimidazo[1,2-a]pyridin-3-ylsulfonyl)urea Sulfosulfuron C16H18N6O7S2 CCS(=O)(=O)C1=C(N2C=CC=CC2=N1)S(=O)(=O)NC(=O)NC3=NC(=CC(=N3)OC)OC InChI=1S/C16H18N6O7S2/c1-4-30(24,25)13-14(22-8-6-5-7-10(22)17-13)31(26,27)21-16(23)20-15-18-11(28-2)9-12(19-15)29-3/h5-9H,4H2,1-3H3,(H2,18,19,20,21,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported no data with Negative RMS: Sweden - CoRMS: Ireland Sulfosulfuron (Renewal Assessment Report) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron 14Jul2014 2014 doi:10.2903/j.efsa.2014.3764
+Sulfosulfuron 141776-32-1 single chemical entity Component is identical to the substance Sulfosulfuron 141776-32-1 1-(4,6-dimethoxypyrimidin-2-yl)-3-(2-ethylsulfonylimidazo[1,2-a]pyridin-3-ylsulfonyl)urea Sulfosulfuron C16H18N6O7S2 CCS(=O)(=O)C1=C(N2C=CC=CC2=N1)S(=O)(=O)NC(=O)NC3=NC(=CC(=N3)OC)OC InChI=1S/C16H18N6O7S2/c1-4-30(24,25)13-14(22-8-6-5-7-10(22)17-13)31(26,27)21-16(23)20-15-18-11(28-2)9-12(19-15)29-3/h5-9H,4H2,1-3H3,(H2,18,19,20,21,23) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported no data without Negative RMS: Sweden - CoRMS: Ireland Sulfosulfuron (Renewal Assessment Report) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron 14Jul2014 2014 doi:10.2903/j.efsa.2014.3764
+Sulfosulfuron 141776-32-1 single chemical entity Component is identical to the substance Sulfosulfuron 141776-32-1 1-(4,6-dimethoxypyrimidin-2-yl)-3-(2-ethylsulfonylimidazo[1,2-a]pyridin-3-ylsulfonyl)urea Sulfosulfuron C16H18N6O7S2 CCS(=O)(=O)C1=C(N2C=CC=CC2=N1)S(=O)(=O)NC(=O)NC3=NC(=CC(=N3)OC)OC InChI=1S/C16H18N6O7S2/c1-4-30(24,25)13-14(22-8-6-5-7-10(22)17-13)31(26,27)21-16(23)20-15-18-11(28-2)9-12(19-15)29-3/h5-9H,4H2,1-3H3,(H2,18,19,20,21,23) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported no data with Negative RMS: Sweden - CoRMS: Ireland Sulfosulfuron (Renewal Assessment Report) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron 14Jul2014 2014 doi:10.2903/j.efsa.2014.3764
+Sulfosulfuron 141776-32-1 single chemical entity Component is identical to the substance Sulfosulfuron 141776-32-1 1-(4,6-dimethoxypyrimidin-2-yl)-3-(2-ethylsulfonylimidazo[1,2-a]pyridin-3-ylsulfonyl)urea Sulfosulfuron C16H18N6O7S2 CCS(=O)(=O)C1=C(N2C=CC=CC2=N1)S(=O)(=O)NC(=O)NC3=NC(=CC(=N3)OC)OC InChI=1S/C16H18N6O7S2/c1-4-30(24,25)13-14(22-8-6-5-7-10(22)17-13)31(26,27)21-16(23)20-15-18-11(28-2)9-12(19-15)29-3/h5-9H,4H2,1-3H3,(H2,18,19,20,21,23) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data without Positive RMS: Sweden - CoRMS: Ireland Sulfosulfuron (Renewal Assessment Report) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron 14Jul2014 2014 doi:10.2903/j.efsa.2014.3764
+Sulfosulfuron 141776-32-1 single chemical entity Component is identical to the substance Sulfosulfuron 141776-32-1 1-(4,6-dimethoxypyrimidin-2-yl)-3-(2-ethylsulfonylimidazo[1,2-a]pyridin-3-ylsulfonyl)urea Sulfosulfuron C16H18N6O7S2 CCS(=O)(=O)C1=C(N2C=CC=CC2=N1)S(=O)(=O)NC(=O)NC3=NC(=CC(=N3)OC)OC InChI=1S/C16H18N6O7S2/c1-4-30(24,25)13-14(22-8-6-5-7-10(22)17-13)31(26,27)21-16(23)20-15-18-11(28-2)9-12(19-15)29-3/h5-9H,4H2,1-3H3,(H2,18,19,20,21,23) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data with Negative RMS: Sweden - CoRMS: Ireland Sulfosulfuron (Renewal Assessment Report) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron 14Jul2014 2014 doi:10.2903/j.efsa.2014.3764
+Sulfosulfuron 141776-32-1 single chemical entity Component is identical to the substance Sulfosulfuron 141776-32-1 1-(4,6-dimethoxypyrimidin-2-yl)-3-(2-ethylsulfonylimidazo[1,2-a]pyridin-3-ylsulfonyl)urea Sulfosulfuron C16H18N6O7S2 CCS(=O)(=O)C1=C(N2C=CC=CC2=N1)S(=O)(=O)NC(=O)NC3=NC(=CC(=N3)OC)OC InChI=1S/C16H18N6O7S2/c1-4-30(24,25)13-14(22-8-6-5-7-10(22)17-13)31(26,27)21-16(23)20-15-18-11(28-2)9-12(19-15)29-3/h5-9H,4H2,1-3H3,(H2,18,19,20,21,23) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 72.0000000000 h yes, historical not applicable Negative indirect-toxicokinetic investigations RMS: Sweden - CoRMS: Ireland Sulfosulfuron (Renewal Assessment Report) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron 14Jul2014 2014 doi:10.2903/j.efsa.2014.3764
+Sulfosulfuron 141776-32-1 single chemical entity Component is identical to the substance Sulfosulfuron 141776-32-1 1-(4,6-dimethoxypyrimidin-2-yl)-3-(2-ethylsulfonylimidazo[1,2-a]pyridin-3-ylsulfonyl)urea Sulfosulfuron C16H18N6O7S2 CCS(=O)(=O)C1=C(N2C=CC=CC2=N1)S(=O)(=O)NC(=O)NC3=NC(=CC(=N3)OC)OC InChI=1S/C16H18N6O7S2/c1-4-30(24,25)13-14(22-8-6-5-7-10(22)17-13)31(26,27)21-16(23)20-15-18-11(28-2)9-12(19-15)29-3/h5-9H,4H2,1-3H3,(H2,18,19,20,21,23) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 48.0000000000 h yes, historical not applicable Negative indirect-toxicokinetic investigations RMS: Sweden - CoRMS: Ireland Sulfosulfuron (Renewal Assessment Report) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron 14Jul2014 2014 doi:10.2903/j.efsa.2014.3764
+Sulfosulfuron 141776-32-1 single chemical entity Component is identical to the substance Sulfosulfuron 141776-32-1 1-(4,6-dimethoxypyrimidin-2-yl)-3-(2-ethylsulfonylimidazo[1,2-a]pyridin-3-ylsulfonyl)urea Sulfosulfuron C16H18N6O7S2 CCS(=O)(=O)C1=C(N2C=CC=CC2=N1)S(=O)(=O)NC(=O)NC3=NC(=CC(=N3)OC)OC InChI=1S/C16H18N6O7S2/c1-4-30(24,25)13-14(22-8-6-5-7-10(22)17-13)31(26,27)21-16(23)20-15-18-11(28-2)9-12(19-15)29-3/h5-9H,4H2,1-3H3,(H2,18,19,20,21,23) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes, historical not applicable Negative indirect-toxicokinetic investigations RMS: Sweden - CoRMS: Ireland Sulfosulfuron (Renewal Assessment Report) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron 14Jul2014 2014 doi:10.2903/j.efsa.2014.3764
+Sulfosulfuron 141776-32-1 single chemical entity Component is a metabolite of the substance N-(carbamimidoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide N-(carbamimidoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide Not in list C11H14N6O5S2 NC(=N)NC(=O)NS(=O)(=O)c1c(nc2ccccn12)S(=O)(=O)CC InChI=1/C11H14N6O5S2/c1-2-23(19,20)8-9(17-6-4-3-5-7(17)14-8)24(21,22)16-11(18)15-10(12)13/h3-6H,2H2,1H3,(H5,12,13,15,16,18) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Ireland Sulfosulfuron (Renewal Assessment Report) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron 14Jul2014 2014 doi:10.2903/j.efsa.2014.3764
+Sulfosulfuron 141776-32-1 single chemical entity Component is a metabolite of the substance N-(carbamimidoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide N-(carbamimidoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide Not in list C11H14N6O5S2 NC(=N)NC(=O)NS(=O)(=O)c1c(nc2ccccn12)S(=O)(=O)CC InChI=1/C11H14N6O5S2/c1-2-23(19,20)8-9(17-6-4-3-5-7(17)14-8)24(21,22)16-11(18)15-10(12)13/h3-6H,2H2,1H3,(H5,12,13,15,16,18) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Ireland Sulfosulfuron (Renewal Assessment Report) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron 14Jul2014 2014 doi:10.2903/j.efsa.2014.3764
+Sulfosulfuron 141776-32-1 single chemical entity Component is a metabolite of the substance N-(carbamimidoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide N-(carbamimidoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide Not in list C11H14N6O5S2 NC(=N)NC(=O)NS(=O)(=O)c1c(nc2ccccn12)S(=O)(=O)CC InChI=1/C11H14N6O5S2/c1-2-23(19,20)8-9(17-6-4-3-5-7(17)14-8)24(21,22)16-11(18)15-10(12)13/h3-6H,2H2,1H3,(H5,12,13,15,16,18) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Ireland Sulfosulfuron (Renewal Assessment Report) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron 14Jul2014 2014 doi:10.2903/j.efsa.2014.3764
+Sulfosulfuron 141776-32-1 single chemical entity Component is a metabolite of the substance N-(carbamimidoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide N-(carbamimidoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide Not in list C11H14N6O5S2 NC(=N)NC(=O)NS(=O)(=O)c1c(nc2ccccn12)S(=O)(=O)CC InChI=1/C11H14N6O5S2/c1-2-23(19,20)8-9(17-6-4-3-5-7(17)14-8)24(21,22)16-11(18)15-10(12)13/h3-6H,2H2,1H3,(H5,12,13,15,16,18) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Ireland Sulfosulfuron (Renewal Assessment Report) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron 14Jul2014 2014 doi:10.2903/j.efsa.2014.3764
+Sulfosulfuron 141776-32-1 single chemical entity Component is a metabolite of the substance N-(carbamimidoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide N-(carbamimidoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide Not in list C11H14N6O5S2 NC(=N)NC(=O)NS(=O)(=O)c1c(nc2ccccn12)S(=O)(=O)CC InChI=1/C11H14N6O5S2/c1-2-23(19,20)8-9(17-6-4-3-5-7(17)14-8)24(21,22)16-11(18)15-10(12)13/h3-6H,2H2,1H3,(H5,12,13,15,16,18) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Ireland Sulfosulfuron (Renewal Assessment Report) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron 14Jul2014 2014 doi:10.2903/j.efsa.2014.3764
+Sulfosulfuron 141776-32-1 single chemical entity Component is a metabolite of the substance N-(carbamimidoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide N-(carbamimidoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide Not in list C11H14N6O5S2 NC(=N)NC(=O)NS(=O)(=O)c1c(nc2ccccn12)S(=O)(=O)CC InChI=1/C11H14N6O5S2/c1-2-23(19,20)8-9(17-6-4-3-5-7(17)14-8)24(21,22)16-11(18)15-10(12)13/h3-6H,2H2,1H3,(H5,12,13,15,16,18) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Ireland Sulfosulfuron (Renewal Assessment Report) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron 14Jul2014 2014 doi:10.2903/j.efsa.2014.3764
+Sulfosulfuron 141776-32-1 single chemical entity Component is a metabolite of the substance N-(carbamimidoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide N-(carbamimidoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide Not in list C11H14N6O5S2 NC(=N)NC(=O)NS(=O)(=O)c1c(nc2ccccn12)S(=O)(=O)CC InChI=1/C11H14N6O5S2/c1-2-23(19,20)8-9(17-6-4-3-5-7(17)14-8)24(21,22)16-11(18)15-10(12)13/h3-6H,2H2,1H3,(H5,12,13,15,16,18) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Ireland Sulfosulfuron (Renewal Assessment Report) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron 14Jul2014 2014 doi:10.2903/j.efsa.2014.3764
+Sulfosulfuron 141776-32-1 single chemical entity Component is a metabolite of the substance N-(carbamimidoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide N-(carbamimidoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide Not in list C11H14N6O5S2 NC(=N)NC(=O)NS(=O)(=O)c1c(nc2ccccn12)S(=O)(=O)CC InChI=1/C11H14N6O5S2/c1-2-23(19,20)8-9(17-6-4-3-5-7(17)14-8)24(21,22)16-11(18)15-10(12)13/h3-6H,2H2,1H3,(H5,12,13,15,16,18) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Ireland Sulfosulfuron (Renewal Assessment Report) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron 14Jul2014 2014 doi:10.2903/j.efsa.2014.3764
+Sulfosulfuron 141776-32-1 single chemical entity Component is a metabolite of the substance N-(carbamimidoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide N-(carbamimidoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide Not in list C11H14N6O5S2 NC(=N)NC(=O)NS(=O)(=O)c1c(nc2ccccn12)S(=O)(=O)CC InChI=1/C11H14N6O5S2/c1-2-23(19,20)8-9(17-6-4-3-5-7(17)14-8)24(21,22)16-11(18)15-10(12)13/h3-6H,2H2,1H3,(H5,12,13,15,16,18) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Ireland Sulfosulfuron (Renewal Assessment Report) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron 14Jul2014 2014 doi:10.2903/j.efsa.2014.3764
+Sulfosulfuron 141776-32-1 single chemical entity Component is a metabolite of the substance N-(carbamimidoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide N-(carbamimidoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide Not in list C11H14N6O5S2 NC(=N)NC(=O)NS(=O)(=O)c1c(nc2ccccn12)S(=O)(=O)CC InChI=1/C11H14N6O5S2/c1-2-23(19,20)8-9(17-6-4-3-5-7(17)14-8)24(21,22)16-11(18)15-10(12)13/h3-6H,2H2,1H3,(H5,12,13,15,16,18) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Ireland Sulfosulfuron (Renewal Assessment Report) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron 14Jul2014 2014 doi:10.2903/j.efsa.2014.3764
+Sulfosulfuron 141776-32-1 single chemical entity Component is a metabolite of the substance N-(carbamimidoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide N-(carbamimidoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide Not in list C11H14N6O5S2 NC(=N)NC(=O)NS(=O)(=O)c1c(nc2ccccn12)S(=O)(=O)CC InChI=1/C11H14N6O5S2/c1-2-23(19,20)8-9(17-6-4-3-5-7(17)14-8)24(21,22)16-11(18)15-10(12)13/h3-6H,2H2,1H3,(H5,12,13,15,16,18) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Ireland Sulfosulfuron (Renewal Assessment Report) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron 14Jul2014 2014 doi:10.2903/j.efsa.2014.3764
+Sulfosulfuron 141776-32-1 single chemical entity Component is a metabolite of the substance N-(carbamimidoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide N-(carbamimidoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide Not in list C11H14N6O5S2 NC(=N)NC(=O)NS(=O)(=O)c1c(nc2ccccn12)S(=O)(=O)CC InChI=1/C11H14N6O5S2/c1-2-23(19,20)8-9(17-6-4-3-5-7(17)14-8)24(21,22)16-11(18)15-10(12)13/h3-6H,2H2,1H3,(H5,12,13,15,16,18) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Ireland Sulfosulfuron (Renewal Assessment Report) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron 14Jul2014 2014 doi:10.2903/j.efsa.2014.3764
+Sulfosulfuron 141776-32-1 single chemical entity Component is a metabolite of the substance N-(carbamimidoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide N-(carbamimidoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide Not in list C11H14N6O5S2 NC(=N)NC(=O)NS(=O)(=O)c1c(nc2ccccn12)S(=O)(=O)CC InChI=1/C11H14N6O5S2/c1-2-23(19,20)8-9(17-6-4-3-5-7(17)14-8)24(21,22)16-11(18)15-10(12)13/h3-6H,2H2,1H3,(H5,12,13,15,16,18) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Ireland Sulfosulfuron (Renewal Assessment Report) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron 14Jul2014 2014 doi:10.2903/j.efsa.2014.3764
+Sulfosulfuron 141776-32-1 single chemical entity Component is a metabolite of the substance N-(carbamimidoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide N-(carbamimidoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide Not in list C11H14N6O5S2 NC(=N)NC(=O)NS(=O)(=O)c1c(nc2ccccn12)S(=O)(=O)CC InChI=1/C11H14N6O5S2/c1-2-23(19,20)8-9(17-6-4-3-5-7(17)14-8)24(21,22)16-11(18)15-10(12)13/h3-6H,2H2,1H3,(H5,12,13,15,16,18) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Ireland Sulfosulfuron (Renewal Assessment Report) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron 14Jul2014 2014 doi:10.2903/j.efsa.2014.3764
+Sulfosulfuron 141776-32-1 single chemical entity Component is a metabolite of the substance N-(carbamoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide N-(carbamoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide Not in list C11H13N5O6S2 NC(=O)NC(=O)NS(=O)(=O)c1c(nc2ccccn12)S(=O)(=O)CC InChI=1/C11H13N5O6S2/c1-2-23(19,20)8-9(16-6-4-3-5-7(16)13-8)24(21,22)15-11(18)14-10(12)17/h3-6H,2H2,1H3,(H4,12,14,15,17,18) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Ireland Sulfosulfuron (Renewal Assessment Report) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron 14Jul2014 2014 doi:10.2903/j.efsa.2014.3764
+Sulfosulfuron 141776-32-1 single chemical entity Component is a metabolite of the substance N-(carbamoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide N-(carbamoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide Not in list C11H13N5O6S2 NC(=O)NC(=O)NS(=O)(=O)c1c(nc2ccccn12)S(=O)(=O)CC InChI=1/C11H13N5O6S2/c1-2-23(19,20)8-9(16-6-4-3-5-7(16)13-8)24(21,22)15-11(18)14-10(12)17/h3-6H,2H2,1H3,(H4,12,14,15,17,18) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Ireland Sulfosulfuron (Renewal Assessment Report) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron 14Jul2014 2014 doi:10.2903/j.efsa.2014.3764
+Sulfosulfuron 141776-32-1 single chemical entity Component is a metabolite of the substance N-(carbamoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide N-(carbamoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide Not in list C11H13N5O6S2 NC(=O)NC(=O)NS(=O)(=O)c1c(nc2ccccn12)S(=O)(=O)CC InChI=1/C11H13N5O6S2/c1-2-23(19,20)8-9(16-6-4-3-5-7(16)13-8)24(21,22)15-11(18)14-10(12)17/h3-6H,2H2,1H3,(H4,12,14,15,17,18) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Ireland Sulfosulfuron (Renewal Assessment Report) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron 14Jul2014 2014 doi:10.2903/j.efsa.2014.3764
+Sulfosulfuron 141776-32-1 single chemical entity Component is a metabolite of the substance N-(carbamoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide N-(carbamoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide Not in list C11H13N5O6S2 NC(=O)NC(=O)NS(=O)(=O)c1c(nc2ccccn12)S(=O)(=O)CC InChI=1/C11H13N5O6S2/c1-2-23(19,20)8-9(16-6-4-3-5-7(16)13-8)24(21,22)15-11(18)14-10(12)17/h3-6H,2H2,1H3,(H4,12,14,15,17,18) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Ireland Sulfosulfuron (Renewal Assessment Report) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron 14Jul2014 2014 doi:10.2903/j.efsa.2014.3764
+Sulfosulfuron 141776-32-1 single chemical entity Component is a metabolite of the substance N-(carbamoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide N-(carbamoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide Not in list C11H13N5O6S2 NC(=O)NC(=O)NS(=O)(=O)c1c(nc2ccccn12)S(=O)(=O)CC InChI=1/C11H13N5O6S2/c1-2-23(19,20)8-9(16-6-4-3-5-7(16)13-8)24(21,22)15-11(18)14-10(12)17/h3-6H,2H2,1H3,(H4,12,14,15,17,18) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Ireland Sulfosulfuron (Renewal Assessment Report) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron 14Jul2014 2014 doi:10.2903/j.efsa.2014.3764
+Sulfosulfuron 141776-32-1 single chemical entity Component is a metabolite of the substance N-(carbamoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide N-(carbamoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide Not in list C11H13N5O6S2 NC(=O)NC(=O)NS(=O)(=O)c1c(nc2ccccn12)S(=O)(=O)CC InChI=1/C11H13N5O6S2/c1-2-23(19,20)8-9(16-6-4-3-5-7(16)13-8)24(21,22)15-11(18)14-10(12)17/h3-6H,2H2,1H3,(H4,12,14,15,17,18) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Ireland Sulfosulfuron (Renewal Assessment Report) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron 14Jul2014 2014 doi:10.2903/j.efsa.2014.3764
+Sulfosulfuron 141776-32-1 single chemical entity Component is a metabolite of the substance N-(carbamoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide N-(carbamoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide Not in list C11H13N5O6S2 NC(=O)NC(=O)NS(=O)(=O)c1c(nc2ccccn12)S(=O)(=O)CC InChI=1/C11H13N5O6S2/c1-2-23(19,20)8-9(16-6-4-3-5-7(16)13-8)24(21,22)15-11(18)14-10(12)17/h3-6H,2H2,1H3,(H4,12,14,15,17,18) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Ireland Sulfosulfuron (Renewal Assessment Report) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron 14Jul2014 2014 doi:10.2903/j.efsa.2014.3764
+Sulfosulfuron 141776-32-1 single chemical entity Component is a metabolite of the substance N-(carbamoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide N-(carbamoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide Not in list C11H13N5O6S2 NC(=O)NC(=O)NS(=O)(=O)c1c(nc2ccccn12)S(=O)(=O)CC InChI=1/C11H13N5O6S2/c1-2-23(19,20)8-9(16-6-4-3-5-7(16)13-8)24(21,22)15-11(18)14-10(12)17/h3-6H,2H2,1H3,(H4,12,14,15,17,18) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Ireland Sulfosulfuron (Renewal Assessment Report) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron 14Jul2014 2014 doi:10.2903/j.efsa.2014.3764
+Sulfosulfuron 141776-32-1 single chemical entity Component is a metabolite of the substance N-(carbamoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide N-(carbamoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide Not in list C11H13N5O6S2 NC(=O)NC(=O)NS(=O)(=O)c1c(nc2ccccn12)S(=O)(=O)CC InChI=1/C11H13N5O6S2/c1-2-23(19,20)8-9(16-6-4-3-5-7(16)13-8)24(21,22)15-11(18)14-10(12)17/h3-6H,2H2,1H3,(H4,12,14,15,17,18) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Ireland Sulfosulfuron (Renewal Assessment Report) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron 14Jul2014 2014 doi:10.2903/j.efsa.2014.3764
+Sulfosulfuron 141776-32-1 single chemical entity Component is a metabolite of the substance N-(carbamoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide N-(carbamoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide Not in list C11H13N5O6S2 NC(=O)NC(=O)NS(=O)(=O)c1c(nc2ccccn12)S(=O)(=O)CC InChI=1/C11H13N5O6S2/c1-2-23(19,20)8-9(16-6-4-3-5-7(16)13-8)24(21,22)15-11(18)14-10(12)17/h3-6H,2H2,1H3,(H4,12,14,15,17,18) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Ireland Sulfosulfuron (Renewal Assessment Report) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron 14Jul2014 2014 doi:10.2903/j.efsa.2014.3764
+Sulfosulfuron 141776-32-1 single chemical entity Component is a metabolite of the substance N-(carbamoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide N-(carbamoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide Not in list C11H13N5O6S2 NC(=O)NC(=O)NS(=O)(=O)c1c(nc2ccccn12)S(=O)(=O)CC InChI=1/C11H13N5O6S2/c1-2-23(19,20)8-9(16-6-4-3-5-7(16)13-8)24(21,22)15-11(18)14-10(12)17/h3-6H,2H2,1H3,(H4,12,14,15,17,18) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Ireland Sulfosulfuron (Renewal Assessment Report) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron 14Jul2014 2014 doi:10.2903/j.efsa.2014.3764
+Sulfosulfuron 141776-32-1 single chemical entity Component is a metabolite of the substance N-(carbamoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide N-(carbamoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide Not in list C11H13N5O6S2 NC(=O)NC(=O)NS(=O)(=O)c1c(nc2ccccn12)S(=O)(=O)CC InChI=1/C11H13N5O6S2/c1-2-23(19,20)8-9(16-6-4-3-5-7(16)13-8)24(21,22)15-11(18)14-10(12)17/h3-6H,2H2,1H3,(H4,12,14,15,17,18) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Ireland Sulfosulfuron (Renewal Assessment Report) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron 14Jul2014 2014 doi:10.2903/j.efsa.2014.3764
+Sulfosulfuron 141776-32-1 single chemical entity Component is a metabolite of the substance N-(carbamoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide N-(carbamoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide Not in list C11H13N5O6S2 NC(=O)NC(=O)NS(=O)(=O)c1c(nc2ccccn12)S(=O)(=O)CC InChI=1/C11H13N5O6S2/c1-2-23(19,20)8-9(16-6-4-3-5-7(16)13-8)24(21,22)15-11(18)14-10(12)17/h3-6H,2H2,1H3,(H4,12,14,15,17,18) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Sweden - CoRMS: Ireland Sulfosulfuron (Renewal Assessment Report) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron 14Jul2014 2014 doi:10.2903/j.efsa.2014.3764
+Sulfosulfuron 141776-32-1 single chemical entity Component is a metabolite of the substance N-(carbamoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide N-(carbamoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide Not in list C11H13N5O6S2 NC(=O)NC(=O)NS(=O)(=O)c1c(nc2ccccn12)S(=O)(=O)CC InChI=1/C11H13N5O6S2/c1-2-23(19,20)8-9(16-6-4-3-5-7(16)13-8)24(21,22)15-11(18)14-10(12)17/h3-6H,2H2,1H3,(H4,12,14,15,17,18) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Sweden - CoRMS: Ireland Sulfosulfuron (Renewal Assessment Report) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron 14Jul2014 2014 doi:10.2903/j.efsa.2014.3764
+Tebuconazole 403-640-2 107534-96-3 single chemical entity Component is identical to the substance Tebuconazole 403-640-2 107534-96-3 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol Tebuconazole C16H22ClN3O OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1 InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3 organic compound Other Other gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) W3110 Not reported yes without Negative RMS: Denmark Tebuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole. 03Jan2014 2014 doi:10.2903/j.efsa.2014.3485
+Tebuconazole 403-640-2 107534-96-3 single chemical entity Component is identical to the substance Tebuconazole 403-640-2 107534-96-3 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol Tebuconazole C16H22ClN3O OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1 InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3 organic compound Other Other gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) (k12)p3478 Not reported yes with Negative RMS: Denmark Tebuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole. 03Jan2014 2014 doi:10.2903/j.efsa.2014.3485
+Tebuconazole 403-640-2 107534-96-3 single chemical entity Component is identical to the substance Tebuconazole 403-640-2 107534-96-3 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol Tebuconazole C16H22ClN3O OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1 InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3 organic compound Other Other gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) W3110 Not reported yes with Negative RMS: Denmark Tebuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole. 03Jan2014 2014 doi:10.2903/j.efsa.2014.3485
+Tebuconazole 403-640-2 107534-96-3 single chemical entity Component is identical to the substance Tebuconazole 403-640-2 107534-96-3 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol Tebuconazole C16H22ClN3O OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1 InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3 organic compound Other Other gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) (k12)p3478 Not reported yes without Negative RMS: Denmark Tebuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole. 03Jan2014 2014 doi:10.2903/j.efsa.2014.3485
+Tebuconazole 403-640-2 107534-96-3 single chemical entity Component is identical to the substance Tebuconazole 403-640-2 107534-96-3 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol Tebuconazole C16H22ClN3O OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1 InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Denmark Tebuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole. 03Jan2014 2014 doi:10.2903/j.efsa.2014.3485
+Tebuconazole 403-640-2 107534-96-3 single chemical entity Component is identical to the substance Tebuconazole 403-640-2 107534-96-3 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol Tebuconazole C16H22ClN3O OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1 InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Denmark Tebuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole. 03Jan2014 2014 doi:10.2903/j.efsa.2014.3485
+Tebuconazole 403-640-2 107534-96-3 single chemical entity Component is identical to the substance Tebuconazole 403-640-2 107534-96-3 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol Tebuconazole C16H22ClN3O OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1 InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Denmark Tebuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole. 03Jan2014 2014 doi:10.2903/j.efsa.2014.3485
+Tebuconazole 403-640-2 107534-96-3 single chemical entity Component is identical to the substance Tebuconazole 403-640-2 107534-96-3 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol Tebuconazole C16H22ClN3O OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1 InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Denmark Tebuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole. 03Jan2014 2014 doi:10.2903/j.efsa.2014.3485
+Tebuconazole 403-640-2 107534-96-3 single chemical entity Component is identical to the substance Tebuconazole 403-640-2 107534-96-3 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol Tebuconazole C16H22ClN3O OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1 InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Denmark Tebuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole. 03Jan2014 2014 doi:10.2903/j.efsa.2014.3485
+Tebuconazole 403-640-2 107534-96-3 single chemical entity Component is identical to the substance Tebuconazole 403-640-2 107534-96-3 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol Tebuconazole C16H22ClN3O OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1 InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Denmark Tebuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole. 03Jan2014 2014 doi:10.2903/j.efsa.2014.3485
+Tebuconazole 403-640-2 107534-96-3 single chemical entity Component is identical to the substance Tebuconazole 403-640-2 107534-96-3 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol Tebuconazole C16H22ClN3O OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1 InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Denmark Tebuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole. 03Jan2014 2014 doi:10.2903/j.efsa.2014.3485
+Tebuconazole 403-640-2 107534-96-3 single chemical entity Component is identical to the substance Tebuconazole 403-640-2 107534-96-3 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol Tebuconazole C16H22ClN3O OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1 InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Denmark Tebuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole. 03Jan2014 2014 doi:10.2903/j.efsa.2014.3485
+Tebuconazole 403-640-2 107534-96-3 single chemical entity Component is identical to the substance Tebuconazole 403-640-2 107534-96-3 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol Tebuconazole C16H22ClN3O OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1 InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Denmark Tebuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole. 03Jan2014 2014 doi:10.2903/j.efsa.2014.3485
+Tebuconazole 403-640-2 107534-96-3 single chemical entity Component is identical to the substance Tebuconazole 403-640-2 107534-96-3 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol Tebuconazole C16H22ClN3O OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1 InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Denmark Tebuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole. 03Jan2014 2014 doi:10.2903/j.efsa.2014.3485
+Tebuconazole 403-640-2 107534-96-3 single chemical entity Component is identical to the substance Tebuconazole 403-640-2 107534-96-3 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol Tebuconazole C16H22ClN3O OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1 InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Denmark Tebuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole. 03Jan2014 2014 doi:10.2903/j.efsa.2014.3485
+Tebuconazole 403-640-2 107534-96-3 single chemical entity Component is identical to the substance Tebuconazole 403-640-2 107534-96-3 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol Tebuconazole C16H22ClN3O OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1 InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Denmark Tebuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole. 03Jan2014 2014 doi:10.2903/j.efsa.2014.3485
+Tebuconazole 403-640-2 107534-96-3 single chemical entity Component is identical to the substance Tebuconazole 403-640-2 107534-96-3 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol Tebuconazole C16H22ClN3O OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1 InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Denmark Tebuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole. 03Jan2014 2014 doi:10.2903/j.efsa.2014.3485
+Tebuconazole 403-640-2 107534-96-3 single chemical entity Component is identical to the substance Tebuconazole 403-640-2 107534-96-3 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol Tebuconazole C16H22ClN3O OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1 InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Denmark Tebuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole. 03Jan2014 2014 doi:10.2903/j.efsa.2014.3485
+Tebuconazole 403-640-2 107534-96-3 single chemical entity Component is identical to the substance Tebuconazole 403-640-2 107534-96-3 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol Tebuconazole C16H22ClN3O OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1 InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Denmark Tebuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole. 03Jan2014 2014 doi:10.2903/j.efsa.2014.3485
+Tebuconazole 403-640-2 107534-96-3 single chemical entity Component is identical to the substance Tebuconazole 403-640-2 107534-96-3 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol Tebuconazole C16H22ClN3O OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1 InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Denmark Tebuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole. 03Jan2014 2014 doi:10.2903/j.efsa.2014.3485
+Tebuconazole 403-640-2 107534-96-3 single chemical entity Component is identical to the substance Tebuconazole 403-640-2 107534-96-3 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol Tebuconazole C16H22ClN3O OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1 InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Denmark Tebuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole. 03Jan2014 2014 doi:10.2903/j.efsa.2014.3485
+Tebuconazole 403-640-2 107534-96-3 single chemical entity Component is identical to the substance Tebuconazole 403-640-2 107534-96-3 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol Tebuconazole C16H22ClN3O OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1 InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Denmark Tebuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole. 03Jan2014 2014 doi:10.2903/j.efsa.2014.3485
+Tebuconazole 403-640-2 107534-96-3 single chemical entity Component is identical to the substance Tebuconazole 403-640-2 107534-96-3 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol Tebuconazole C16H22ClN3O OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1 InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Denmark Tebuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole. 03Jan2014 2014 doi:10.2903/j.efsa.2014.3485
+Tebuconazole 403-640-2 107534-96-3 single chemical entity Component is identical to the substance Tebuconazole 403-640-2 107534-96-3 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol Tebuconazole C16H22ClN3O OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1 InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Denmark Tebuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole. 03Jan2014 2014 doi:10.2903/j.efsa.2014.3485
+Tebuconazole 403-640-2 107534-96-3 single chemical entity Component is identical to the substance Tebuconazole 403-640-2 107534-96-3 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol Tebuconazole C16H22ClN3O OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1 InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Denmark Tebuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole. 03Jan2014 2014 doi:10.2903/j.efsa.2014.3485
+Tebuconazole 403-640-2 107534-96-3 single chemical entity Component is identical to the substance Tebuconazole 403-640-2 107534-96-3 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol Tebuconazole C16H22ClN3O OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1 InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Denmark Tebuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole. 03Jan2014 2014 doi:10.2903/j.efsa.2014.3485
+Tebuconazole 403-640-2 107534-96-3 single chemical entity Component is identical to the substance Tebuconazole 403-640-2 107534-96-3 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol Tebuconazole C16H22ClN3O OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1 InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Denmark Tebuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole. 03Jan2014 2014 doi:10.2903/j.efsa.2014.3485
+Tebuconazole 403-640-2 107534-96-3 single chemical entity Component is identical to the substance Tebuconazole 403-640-2 107534-96-3 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol Tebuconazole C16H22ClN3O OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1 InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Denmark Tebuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole. 03Jan2014 2014 doi:10.2903/j.efsa.2014.3485
+Tebuconazole 403-640-2 107534-96-3 single chemical entity Component is identical to the substance Tebuconazole 403-640-2 107534-96-3 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol Tebuconazole C16H22ClN3O OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1 InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Denmark Tebuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole. 03Jan2014 2014 doi:10.2903/j.efsa.2014.3485
+Tebuconazole 403-640-2 107534-96-3 single chemical entity Component is identical to the substance Tebuconazole 403-640-2 107534-96-3 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol Tebuconazole C16H22ClN3O OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1 InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Denmark Tebuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole. 03Jan2014 2014 doi:10.2903/j.efsa.2014.3485
+Tebuconazole 403-640-2 107534-96-3 single chemical entity Component is identical to the substance Tebuconazole 403-640-2 107534-96-3 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol Tebuconazole C16H22ClN3O OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1 InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Denmark Tebuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole. 03Jan2014 2014 doi:10.2903/j.efsa.2014.3485
+Tebuconazole 403-640-2 107534-96-3 single chemical entity Component is identical to the substance Tebuconazole 403-640-2 107534-96-3 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol Tebuconazole C16H22ClN3O OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1 InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Denmark Tebuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole. 03Jan2014 2014 doi:10.2903/j.efsa.2014.3485
+Tebuconazole 403-640-2 107534-96-3 single chemical entity Component is identical to the substance Tebuconazole 403-640-2 107534-96-3 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol Tebuconazole C16H22ClN3O OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1 InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported no data with Negative RMS: Denmark Tebuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole. 03Jan2014 2014 doi:10.2903/j.efsa.2014.3485
+Tebuconazole 403-640-2 107534-96-3 single chemical entity Component is identical to the substance Tebuconazole 403-640-2 107534-96-3 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol Tebuconazole C16H22ClN3O OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1 InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported no data without Negative RMS: Denmark Tebuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole. 03Jan2014 2014 doi:10.2903/j.efsa.2014.3485
+Tebuconazole 403-640-2 107534-96-3 single chemical entity Component is identical to the substance Tebuconazole 403-640-2 107534-96-3 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol Tebuconazole C16H22ClN3O OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1 InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: Denmark Tebuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole. 03Jan2014 2014 doi:10.2903/j.efsa.2014.3485
+Tebuconazole 403-640-2 107534-96-3 single chemical entity Component is identical to the substance Tebuconazole 403-640-2 107534-96-3 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol Tebuconazole C16H22ClN3O OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1 InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: Denmark Tebuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole. 03Jan2014 2014 doi:10.2903/j.efsa.2014.3485
+Tebuconazole 403-640-2 107534-96-3 single chemical entity Component is identical to the substance Tebuconazole 403-640-2 107534-96-3 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol Tebuconazole C16H22ClN3O OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1 InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3 organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) Yes Acceptable Hamster (as animal) CHO Not reported no data without Negative RMS: Denmark Tebuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole. 03Jan2014 2014 doi:10.2903/j.efsa.2014.3485
+Tebuconazole 403-640-2 107534-96-3 single chemical entity Component is identical to the substance Tebuconazole 403-640-2 107534-96-3 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol Tebuconazole C16H22ClN3O OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1 InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3 organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) Yes Acceptable Hamster (as animal) CHO Not reported no data with Negative RMS: Denmark Tebuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole. 03Jan2014 2014 doi:10.2903/j.efsa.2014.3485
+Tebuconazole 403-640-2 107534-96-3 single chemical entity Component is identical to the substance Tebuconazole 403-640-2 107534-96-3 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol Tebuconazole C16H22ClN3O OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1 InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3 organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported no data without Negative RMS: Denmark Tebuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole. 03Jan2014 2014 doi:10.2903/j.efsa.2014.3485
+Tebuconazole 403-640-2 107534-96-3 single chemical entity Component is identical to the substance Tebuconazole 403-640-2 107534-96-3 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol Tebuconazole C16H22ClN3O OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1 InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3 organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes without Negative RMS: Denmark Tebuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole. 03Jan2014 2014 doi:10.2903/j.efsa.2014.3485
+Tebuconazole 403-640-2 107534-96-3 single chemical entity Component is identical to the substance Tebuconazole 403-640-2 107534-96-3 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol Tebuconazole C16H22ClN3O OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1 InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3 organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes without Negative RMS: Denmark Tebuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole. 03Jan2014 2014 doi:10.2903/j.efsa.2014.3485
+Tebuconazole 403-640-2 107534-96-3 single chemical entity Component is identical to the substance Tebuconazole 403-640-2 107534-96-3 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol Tebuconazole C16H22ClN3O OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1 InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3 organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes with Negative RMS: Denmark Tebuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole. 03Jan2014 2014 doi:10.2903/j.efsa.2014.3485
+Tebuconazole 403-640-2 107534-96-3 single chemical entity Component is identical to the substance Tebuconazole 403-640-2 107534-96-3 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol Tebuconazole C16H22ClN3O OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1 InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3 organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes with Negative RMS: Denmark Tebuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole. 03Jan2014 2014 doi:10.2903/j.efsa.2014.3485
+Tebuconazole 403-640-2 107534-96-3 single chemical entity Component is identical to the substance Tebuconazole 403-640-2 107534-96-3 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol Tebuconazole C16H22ClN3O OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1 InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 24.0000000000 h yes not applicable Negative no evidence RMS: Denmark Tebuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole. 03Jan2014 2014 doi:10.2903/j.efsa.2014.3485
+Tebuconazole 403-640-2 107534-96-3 single chemical entity Component is identical to the substance Tebuconazole 403-640-2 107534-96-3 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol Tebuconazole C16H22ClN3O OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1 InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 48.0000000000 h yes not applicable Negative no evidence RMS: Denmark Tebuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole. 03Jan2014 2014 doi:10.2903/j.efsa.2014.3485
+Tebuconazole 403-640-2 107534-96-3 single chemical entity Component is identical to the substance Tebuconazole 403-640-2 107534-96-3 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol Tebuconazole C16H22ClN3O OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1 InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 72.0000000000 h yes not applicable Negative no evidence RMS: Denmark Tebuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole. 03Jan2014 2014 doi:10.2903/j.efsa.2014.3485
+Tebuconazole 403-640-2 107534-96-3 single chemical entity Component is identical to the substance Tebuconazole 403-640-2 107534-96-3 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol Tebuconazole C16H22ClN3O OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1 InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3 organic compound Other Other chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) Yes Acceptable House mouse (as animal) NMRI 50 Male oral: gavage yes not applicable Negative RMS: Denmark Tebuconazole 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole. 03Jan2014 2014 doi:10.2903/j.efsa.2014.3485
+Tebufenpyrad 119168-77-3 single chemical entity Component is identical to the substance Tebufenpyrad 119168-77-3 N-(4-tert-butylbenzyl)-4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide Tebufenpyrad C18H24ClN3O O=C(NCC2=CC=C(C(C)(C)C)C=C2)C1=C(Cl)C(CC)=NN1C InChI=1S/C18H24ClN3O/c1-6-14-15(19)16(22(5)21-14)17(23)20-11-12-7-9-13(10-8-12)18(2,3)4/h7-10H,6,11H2,1-5H3,(H,20,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany Tebufenpyrad 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad 30Mar2009 2009 doi:10.2903/j.efsa.2009.192r
+Tebufenpyrad 119168-77-3 single chemical entity Component is identical to the substance Tebufenpyrad 119168-77-3 N-(4-tert-butylbenzyl)-4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide Tebufenpyrad C18H24ClN3O O=C(NCC2=CC=C(C(C)(C)C)C=C2)C1=C(Cl)C(CC)=NN1C InChI=1S/C18H24ClN3O/c1-6-14-15(19)16(22(5)21-14)17(23)20-11-12-7-9-13(10-8-12)18(2,3)4/h7-10H,6,11H2,1-5H3,(H,20,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Germany Tebufenpyrad 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad 30Mar2009 2009 doi:10.2903/j.efsa.2009.192r
+Tebufenpyrad 119168-77-3 single chemical entity Component is identical to the substance Tebufenpyrad 119168-77-3 N-(4-tert-butylbenzyl)-4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide Tebufenpyrad C18H24ClN3O O=C(NCC2=CC=C(C(C)(C)C)C=C2)C1=C(Cl)C(CC)=NN1C InChI=1S/C18H24ClN3O/c1-6-14-15(19)16(22(5)21-14)17(23)20-11-12-7-9-13(10-8-12)18(2,3)4/h7-10H,6,11H2,1-5H3,(H,20,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Germany Tebufenpyrad 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad 30Mar2009 2009 doi:10.2903/j.efsa.2009.192r
+Tebufenpyrad 119168-77-3 single chemical entity Component is identical to the substance Tebufenpyrad 119168-77-3 N-(4-tert-butylbenzyl)-4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide Tebufenpyrad C18H24ClN3O O=C(NCC2=CC=C(C(C)(C)C)C=C2)C1=C(Cl)C(CC)=NN1C InChI=1S/C18H24ClN3O/c1-6-14-15(19)16(22(5)21-14)17(23)20-11-12-7-9-13(10-8-12)18(2,3)4/h7-10H,6,11H2,1-5H3,(H,20,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Germany Tebufenpyrad 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad 30Mar2009 2009 doi:10.2903/j.efsa.2009.192r
+Tebufenpyrad 119168-77-3 single chemical entity Component is identical to the substance Tebufenpyrad 119168-77-3 N-(4-tert-butylbenzyl)-4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide Tebufenpyrad C18H24ClN3O O=C(NCC2=CC=C(C(C)(C)C)C=C2)C1=C(Cl)C(CC)=NN1C InChI=1S/C18H24ClN3O/c1-6-14-15(19)16(22(5)21-14)17(23)20-11-12-7-9-13(10-8-12)18(2,3)4/h7-10H,6,11H2,1-5H3,(H,20,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany Tebufenpyrad 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad 30Mar2009 2009 doi:10.2903/j.efsa.2009.192r
+Tebufenpyrad 119168-77-3 single chemical entity Component is identical to the substance Tebufenpyrad 119168-77-3 N-(4-tert-butylbenzyl)-4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide Tebufenpyrad C18H24ClN3O O=C(NCC2=CC=C(C(C)(C)C)C=C2)C1=C(Cl)C(CC)=NN1C InChI=1S/C18H24ClN3O/c1-6-14-15(19)16(22(5)21-14)17(23)20-11-12-7-9-13(10-8-12)18(2,3)4/h7-10H,6,11H2,1-5H3,(H,20,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany Tebufenpyrad 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad 30Mar2009 2009 doi:10.2903/j.efsa.2009.192r
+Tebufenpyrad 119168-77-3 single chemical entity Component is identical to the substance Tebufenpyrad 119168-77-3 N-(4-tert-butylbenzyl)-4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide Tebufenpyrad C18H24ClN3O O=C(NCC2=CC=C(C(C)(C)C)C=C2)C1=C(Cl)C(CC)=NN1C InChI=1S/C18H24ClN3O/c1-6-14-15(19)16(22(5)21-14)17(23)20-11-12-7-9-13(10-8-12)18(2,3)4/h7-10H,6,11H2,1-5H3,(H,20,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany Tebufenpyrad 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad 30Mar2009 2009 doi:10.2903/j.efsa.2009.192r
+Tebufenpyrad 119168-77-3 single chemical entity Component is identical to the substance Tebufenpyrad 119168-77-3 N-(4-tert-butylbenzyl)-4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide Tebufenpyrad C18H24ClN3O O=C(NCC2=CC=C(C(C)(C)C)C=C2)C1=C(Cl)C(CC)=NN1C InChI=1S/C18H24ClN3O/c1-6-14-15(19)16(22(5)21-14)17(23)20-11-12-7-9-13(10-8-12)18(2,3)4/h7-10H,6,11H2,1-5H3,(H,20,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany Tebufenpyrad 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad 30Mar2009 2009 doi:10.2903/j.efsa.2009.192r
+Tebufenpyrad 119168-77-3 single chemical entity Component is identical to the substance Tebufenpyrad 119168-77-3 N-(4-tert-butylbenzyl)-4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide Tebufenpyrad C18H24ClN3O O=C(NCC2=CC=C(C(C)(C)C)C=C2)C1=C(Cl)C(CC)=NN1C InChI=1S/C18H24ClN3O/c1-6-14-15(19)16(22(5)21-14)17(23)20-11-12-7-9-13(10-8-12)18(2,3)4/h7-10H,6,11H2,1-5H3,(H,20,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Germany Tebufenpyrad 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad 30Mar2009 2009 doi:10.2903/j.efsa.2009.192r
+Tebufenpyrad 119168-77-3 single chemical entity Component is identical to the substance Tebufenpyrad 119168-77-3 N-(4-tert-butylbenzyl)-4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide Tebufenpyrad C18H24ClN3O O=C(NCC2=CC=C(C(C)(C)C)C=C2)C1=C(Cl)C(CC)=NN1C InChI=1S/C18H24ClN3O/c1-6-14-15(19)16(22(5)21-14)17(23)20-11-12-7-9-13(10-8-12)18(2,3)4/h7-10H,6,11H2,1-5H3,(H,20,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany Tebufenpyrad 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad 30Mar2009 2009 doi:10.2903/j.efsa.2009.192r
+Tebufenpyrad 119168-77-3 single chemical entity Component is identical to the substance Tebufenpyrad 119168-77-3 N-(4-tert-butylbenzyl)-4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide Tebufenpyrad C18H24ClN3O O=C(NCC2=CC=C(C(C)(C)C)C=C2)C1=C(Cl)C(CC)=NN1C InChI=1S/C18H24ClN3O/c1-6-14-15(19)16(22(5)21-14)17(23)20-11-12-7-9-13(10-8-12)18(2,3)4/h7-10H,6,11H2,1-5H3,(H,20,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany Tebufenpyrad 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad 30Mar2009 2009 doi:10.2903/j.efsa.2009.192r
+Tebufenpyrad 119168-77-3 single chemical entity Component is identical to the substance Tebufenpyrad 119168-77-3 N-(4-tert-butylbenzyl)-4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide Tebufenpyrad C18H24ClN3O O=C(NCC2=CC=C(C(C)(C)C)C=C2)C1=C(Cl)C(CC)=NN1C InChI=1S/C18H24ClN3O/c1-6-14-15(19)16(22(5)21-14)17(23)20-11-12-7-9-13(10-8-12)18(2,3)4/h7-10H,6,11H2,1-5H3,(H,20,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany Tebufenpyrad 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad 30Mar2009 2009 doi:10.2903/j.efsa.2009.192r
+Tebufenpyrad 119168-77-3 single chemical entity Component is identical to the substance Tebufenpyrad 119168-77-3 N-(4-tert-butylbenzyl)-4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide Tebufenpyrad C18H24ClN3O O=C(NCC2=CC=C(C(C)(C)C)C=C2)C1=C(Cl)C(CC)=NN1C InChI=1S/C18H24ClN3O/c1-6-14-15(19)16(22(5)21-14)17(23)20-11-12-7-9-13(10-8-12)18(2,3)4/h7-10H,6,11H2,1-5H3,(H,20,23) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: Germany Tebufenpyrad 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad 30Mar2009 2009 doi:10.2903/j.efsa.2009.192r
+Tebufenpyrad 119168-77-3 single chemical entity Component is identical to the substance Tebufenpyrad 119168-77-3 N-(4-tert-butylbenzyl)-4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide Tebufenpyrad C18H24ClN3O O=C(NCC2=CC=C(C(C)(C)C)C=C2)C1=C(Cl)C(CC)=NN1C InChI=1S/C18H24ClN3O/c1-6-14-15(19)16(22(5)21-14)17(23)20-11-12-7-9-13(10-8-12)18(2,3)4/h7-10H,6,11H2,1-5H3,(H,20,23) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: Germany Tebufenpyrad 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad 30Mar2009 2009 doi:10.2903/j.efsa.2009.192r
+Tebufenpyrad 119168-77-3 single chemical entity Component is identical to the substance Tebufenpyrad 119168-77-3 N-(4-tert-butylbenzyl)-4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide Tebufenpyrad C18H24ClN3O O=C(NCC2=CC=C(C(C)(C)C)C=C2)C1=C(Cl)C(CC)=NN1C InChI=1S/C18H24ClN3O/c1-6-14-15(19)16(22(5)21-14)17(23)20-11-12-7-9-13(10-8-12)18(2,3)4/h7-10H,6,11H2,1-5H3,(H,20,23) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Germany Tebufenpyrad 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad 30Mar2009 2009 doi:10.2903/j.efsa.2009.192r
+Tebufenpyrad 119168-77-3 single chemical entity Component is identical to the substance Tebufenpyrad 119168-77-3 N-(4-tert-butylbenzyl)-4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide Tebufenpyrad C18H24ClN3O O=C(NCC2=CC=C(C(C)(C)C)C=C2)C1=C(Cl)C(CC)=NN1C InChI=1S/C18H24ClN3O/c1-6-14-15(19)16(22(5)21-14)17(23)20-11-12-7-9-13(10-8-12)18(2,3)4/h7-10H,6,11H2,1-5H3,(H,20,23) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Ambiguous RMS: Germany Tebufenpyrad 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad 30Mar2009 2009 doi:10.2903/j.efsa.2009.192r
+Tebufenpyrad 119168-77-3 single chemical entity Component is identical to the substance Tebufenpyrad 119168-77-3 N-(4-tert-butylbenzyl)-4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide Tebufenpyrad C18H24ClN3O O=C(NCC2=CC=C(C(C)(C)C)C=C2)C1=C(Cl)C(CC)=NN1C InChI=1S/C18H24ClN3O/c1-6-14-15(19)16(22(5)21-14)17(23)20-11-12-7-9-13(10-8-12)18(2,3)4/h7-10H,6,11H2,1-5H3,(H,20,23) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) hepatocytes Not reported yes, concurrent vehicle with Ambiguous RMS: Germany Tebufenpyrad 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad 30Mar2009 2009 doi:10.2903/j.efsa.2009.192r
+Tebufenpyrad 119168-77-3 single chemical entity Component is identical to the substance Tebufenpyrad 119168-77-3 N-(4-tert-butylbenzyl)-4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide Tebufenpyrad C18H24ClN3O O=C(NCC2=CC=C(C(C)(C)C)C=C2)C1=C(Cl)C(CC)=NN1C InChI=1S/C18H24ClN3O/c1-6-14-15(19)16(22(5)21-14)17(23)20-11-12-7-9-13(10-8-12)18(2,3)4/h7-10H,6,11H2,1-5H3,(H,20,23) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) hepatocytes Not reported yes, concurrent vehicle without Positive RMS: Germany Tebufenpyrad 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad 30Mar2009 2009 doi:10.2903/j.efsa.2009.192r
+Tebufenpyrad 119168-77-3 single chemical entity Component is identical to the substance Tebufenpyrad 119168-77-3 N-(4-tert-butylbenzyl)-4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide Tebufenpyrad C18H24ClN3O O=C(NCC2=CC=C(C(C)(C)C)C=C2)C1=C(Cl)C(CC)=NN1C InChI=1S/C18H24ClN3O/c1-6-14-15(19)16(22(5)21-14)17(23)20-11-12-7-9-13(10-8-12)18(2,3)4/h7-10H,6,11H2,1-5H3,(H,20,23) organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Germany Tebufenpyrad 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad 30Mar2009 2009 doi:10.2903/j.efsa.2009.192r
+Tebufenpyrad 119168-77-3 single chemical entity Component is identical to the substance Tebufenpyrad 119168-77-3 N-(4-tert-butylbenzyl)-4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide Tebufenpyrad C18H24ClN3O O=C(NCC2=CC=C(C(C)(C)C)C=C2)C1=C(Cl)C(CC)=NN1C InChI=1S/C18H24ClN3O/c1-6-14-15(19)16(22(5)21-14)17(23)20-11-12-7-9-13(10-8-12)18(2,3)4/h7-10H,6,11H2,1-5H3,(H,20,23) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Not reported 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect-toxicokinetic investigations RMS: Germany Tebufenpyrad 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad 30Mar2009 2009 doi:10.2903/j.efsa.2009.192r
+Tebufenpyrad 119168-77-3 single chemical entity Component is identical to the substance Tebufenpyrad 119168-77-3 N-(4-tert-butylbenzyl)-4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide Tebufenpyrad C18H24ClN3O O=C(NCC2=CC=C(C(C)(C)C)C=C2)C1=C(Cl)C(CC)=NN1C InChI=1S/C18H24ClN3O/c1-6-14-15(19)16(22(5)21-14)17(23)20-11-12-7-9-13(10-8-12)18(2,3)4/h7-10H,6,11H2,1-5H3,(H,20,23) organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Sprague-Dawley 10 Male oral: gavage 3.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Germany Tebufenpyrad 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad 30Mar2009 2009 doi:10.2903/j.efsa.2009.192r
+Tebufenpyrad 119168-77-3 single chemical entity Component is identical to the substance Tebufenpyrad 119168-77-3 N-(4-tert-butylbenzyl)-4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide Tebufenpyrad C18H24ClN3O O=C(NCC2=CC=C(C(C)(C)C)C=C2)C1=C(Cl)C(CC)=NN1C InChI=1S/C18H24ClN3O/c1-6-14-15(19)16(22(5)21-14)17(23)20-11-12-7-9-13(10-8-12)18(2,3)4/h7-10H,6,11H2,1-5H3,(H,20,23) organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Sprague-Dawley 10 Male oral: gavage 16.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Germany Tebufenpyrad 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad 30Mar2009 2009 doi:10.2903/j.efsa.2009.192r
+Tebufenpyrad 119168-77-3 single chemical entity Component is a metabolite of the substance 2-(4-{[(4-chloro-3-ethyl-1-methyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)-2-methylpropanoic acid 2-(4-{[(4-chloro-3-ethyl-1-methyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)-2-methylpropanoic acid Not in list C17H20ClN3O3 Clc2c(CC)nn(C)c2C(=O)Nc1ccc(cc1)C(C)(C)C(O)=O InChI=1/C17H20ClN3O3/c1-5-12-13(18)14(21(4)20-12)15(22)19-11-8-6-10(7-9-11)17(2,3)16(23)24/h6-9H,5H2,1-4H3,(H,19,22)(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany Tebufenpyrad 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad 30Mar2009 2009 doi:10.2903/j.efsa.2009.192r
+Tebufenpyrad 119168-77-3 single chemical entity Component is a metabolite of the substance 2-(4-{[(4-chloro-3-ethyl-1-methyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)-2-methylpropanoic acid 2-(4-{[(4-chloro-3-ethyl-1-methyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)-2-methylpropanoic acid Not in list C17H20ClN3O3 Clc2c(CC)nn(C)c2C(=O)Nc1ccc(cc1)C(C)(C)C(O)=O InChI=1/C17H20ClN3O3/c1-5-12-13(18)14(21(4)20-12)15(22)19-11-8-6-10(7-9-11)17(2,3)16(23)24/h6-9H,5H2,1-4H3,(H,19,22)(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany Tebufenpyrad 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad 30Mar2009 2009 doi:10.2903/j.efsa.2009.192r
+Tebufenpyrad 119168-77-3 single chemical entity Component is a metabolite of the substance 2-(4-{[(4-chloro-3-ethyl-1-methyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)-2-methylpropanoic acid 2-(4-{[(4-chloro-3-ethyl-1-methyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)-2-methylpropanoic acid Not in list C17H20ClN3O3 Clc2c(CC)nn(C)c2C(=O)Nc1ccc(cc1)C(C)(C)C(O)=O InChI=1/C17H20ClN3O3/c1-5-12-13(18)14(21(4)20-12)15(22)19-11-8-6-10(7-9-11)17(2,3)16(23)24/h6-9H,5H2,1-4H3,(H,19,22)(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany Tebufenpyrad 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad 30Mar2009 2009 doi:10.2903/j.efsa.2009.192r
+Tebufenpyrad 119168-77-3 single chemical entity Component is a metabolite of the substance 2-(4-{[(4-chloro-3-ethyl-1-methyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)-2-methylpropanoic acid 2-(4-{[(4-chloro-3-ethyl-1-methyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)-2-methylpropanoic acid Not in list C17H20ClN3O3 Clc2c(CC)nn(C)c2C(=O)Nc1ccc(cc1)C(C)(C)C(O)=O InChI=1/C17H20ClN3O3/c1-5-12-13(18)14(21(4)20-12)15(22)19-11-8-6-10(7-9-11)17(2,3)16(23)24/h6-9H,5H2,1-4H3,(H,19,22)(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany Tebufenpyrad 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad 30Mar2009 2009 doi:10.2903/j.efsa.2009.192r
+Tebufenpyrad 119168-77-3 single chemical entity Component is a metabolite of the substance 2-(4-{[(4-chloro-3-ethyl-1-methyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)-2-methylpropanoic acid 2-(4-{[(4-chloro-3-ethyl-1-methyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)-2-methylpropanoic acid Not in list C17H20ClN3O3 Clc2c(CC)nn(C)c2C(=O)Nc1ccc(cc1)C(C)(C)C(O)=O InChI=1/C17H20ClN3O3/c1-5-12-13(18)14(21(4)20-12)15(22)19-11-8-6-10(7-9-11)17(2,3)16(23)24/h6-9H,5H2,1-4H3,(H,19,22)(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany Tebufenpyrad 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad 30Mar2009 2009 doi:10.2903/j.efsa.2009.192r
+Tebufenpyrad 119168-77-3 single chemical entity Component is a metabolite of the substance 2-(4-{[(4-chloro-3-ethyl-1-methyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)-2-methylpropanoic acid 2-(4-{[(4-chloro-3-ethyl-1-methyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)-2-methylpropanoic acid Not in list C17H20ClN3O3 Clc2c(CC)nn(C)c2C(=O)Nc1ccc(cc1)C(C)(C)C(O)=O InChI=1/C17H20ClN3O3/c1-5-12-13(18)14(21(4)20-12)15(22)19-11-8-6-10(7-9-11)17(2,3)16(23)24/h6-9H,5H2,1-4H3,(H,19,22)(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany Tebufenpyrad 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad 30Mar2009 2009 doi:10.2903/j.efsa.2009.192r
+Tebufenpyrad 119168-77-3 single chemical entity Component is a metabolite of the substance 2-(4-{[(4-chloro-3-ethyl-1-methyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)-2-methylpropanoic acid 2-(4-{[(4-chloro-3-ethyl-1-methyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)-2-methylpropanoic acid Not in list C17H20ClN3O3 Clc2c(CC)nn(C)c2C(=O)Nc1ccc(cc1)C(C)(C)C(O)=O InChI=1/C17H20ClN3O3/c1-5-12-13(18)14(21(4)20-12)15(22)19-11-8-6-10(7-9-11)17(2,3)16(23)24/h6-9H,5H2,1-4H3,(H,19,22)(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany Tebufenpyrad 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad 30Mar2009 2009 doi:10.2903/j.efsa.2009.192r
+Tebufenpyrad 119168-77-3 single chemical entity Component is a metabolite of the substance 2-(4-{[(4-chloro-3-ethyl-1-methyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)-2-methylpropanoic acid 2-(4-{[(4-chloro-3-ethyl-1-methyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)-2-methylpropanoic acid Not in list C17H20ClN3O3 Clc2c(CC)nn(C)c2C(=O)Nc1ccc(cc1)C(C)(C)C(O)=O InChI=1/C17H20ClN3O3/c1-5-12-13(18)14(21(4)20-12)15(22)19-11-8-6-10(7-9-11)17(2,3)16(23)24/h6-9H,5H2,1-4H3,(H,19,22)(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Germany Tebufenpyrad 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad 30Mar2009 2009 doi:10.2903/j.efsa.2009.192r
+Tebufenpyrad 119168-77-3 single chemical entity Component is a metabolite of the substance 2-(4-{[(4-chloro-3-ethyl-1-methyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)-2-methylpropanoic acid 2-(4-{[(4-chloro-3-ethyl-1-methyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)-2-methylpropanoic acid Not in list C17H20ClN3O3 Clc2c(CC)nn(C)c2C(=O)Nc1ccc(cc1)C(C)(C)C(O)=O InChI=1/C17H20ClN3O3/c1-5-12-13(18)14(21(4)20-12)15(22)19-11-8-6-10(7-9-11)17(2,3)16(23)24/h6-9H,5H2,1-4H3,(H,19,22)(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Germany Tebufenpyrad 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad 30Mar2009 2009 doi:10.2903/j.efsa.2009.192r
+Tebufenpyrad 119168-77-3 single chemical entity Component is a metabolite of the substance 2-(4-{[(4-chloro-3-ethyl-1-methyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)-2-methylpropanoic acid 2-(4-{[(4-chloro-3-ethyl-1-methyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)-2-methylpropanoic acid Not in list C17H20ClN3O3 Clc2c(CC)nn(C)c2C(=O)Nc1ccc(cc1)C(C)(C)C(O)=O InChI=1/C17H20ClN3O3/c1-5-12-13(18)14(21(4)20-12)15(22)19-11-8-6-10(7-9-11)17(2,3)16(23)24/h6-9H,5H2,1-4H3,(H,19,22)(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany Tebufenpyrad 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad 30Mar2009 2009 doi:10.2903/j.efsa.2009.192r
+Tebufenpyrad 119168-77-3 single chemical entity Component is a metabolite of the substance 2-(4-{[(4-chloro-3-ethyl-1-methyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)-2-methylpropanoic acid 2-(4-{[(4-chloro-3-ethyl-1-methyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)-2-methylpropanoic acid Not in list C17H20ClN3O3 Clc2c(CC)nn(C)c2C(=O)Nc1ccc(cc1)C(C)(C)C(O)=O InChI=1/C17H20ClN3O3/c1-5-12-13(18)14(21(4)20-12)15(22)19-11-8-6-10(7-9-11)17(2,3)16(23)24/h6-9H,5H2,1-4H3,(H,19,22)(H,23,24) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative large colonies RMS: Germany Tebufenpyrad 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad 30Mar2009 2009 doi:10.2903/j.efsa.2009.192r
+Tebufenpyrad 119168-77-3 single chemical entity Component is a metabolite of the substance 2-(4-{[(4-chloro-3-ethyl-1-methyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)-2-methylpropanoic acid 2-(4-{[(4-chloro-3-ethyl-1-methyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)-2-methylpropanoic acid Not in list C17H20ClN3O3 Clc2c(CC)nn(C)c2C(=O)Nc1ccc(cc1)C(C)(C)C(O)=O InChI=1/C17H20ClN3O3/c1-5-12-13(18)14(21(4)20-12)15(22)19-11-8-6-10(7-9-11)17(2,3)16(23)24/h6-9H,5H2,1-4H3,(H,19,22)(H,23,24) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative small colonies RMS: Germany Tebufenpyrad 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad 30Mar2009 2009 doi:10.2903/j.efsa.2009.192r
+Tebufenpyrad 119168-77-3 single chemical entity Component is a metabolite of the substance 2-(4-{[(4-chloro-3-ethyl-1-methyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)-2-methylpropanoic acid 2-(4-{[(4-chloro-3-ethyl-1-methyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)-2-methylpropanoic acid Not in list C17H20ClN3O3 Clc2c(CC)nn(C)c2C(=O)Nc1ccc(cc1)C(C)(C)C(O)=O InChI=1/C17H20ClN3O3/c1-5-12-13(18)14(21(4)20-12)15(22)19-11-8-6-10(7-9-11)17(2,3)16(23)24/h6-9H,5H2,1-4H3,(H,19,22)(H,23,24) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative small colonies RMS: Germany Tebufenpyrad 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad 30Mar2009 2009 doi:10.2903/j.efsa.2009.192r
+Tebufenpyrad 119168-77-3 single chemical entity Component is a metabolite of the substance 2-(4-{[(4-chloro-3-ethyl-1-methyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)-2-methylpropanoic acid 2-(4-{[(4-chloro-3-ethyl-1-methyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)-2-methylpropanoic acid Not in list C17H20ClN3O3 Clc2c(CC)nn(C)c2C(=O)Nc1ccc(cc1)C(C)(C)C(O)=O InChI=1/C17H20ClN3O3/c1-5-12-13(18)14(21(4)20-12)15(22)19-11-8-6-10(7-9-11)17(2,3)16(23)24/h6-9H,5H2,1-4H3,(H,19,22)(H,23,24) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative large colonies RMS: Germany Tebufenpyrad 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad 30Mar2009 2009 doi:10.2903/j.efsa.2009.192r
+Tebufenpyrad 119168-77-3 single chemical entity Component is a metabolite of the substance 2-(4-{[(4-chloro-3-ethyl-1-methyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)-2-methylpropanoic acid 2-(4-{[(4-chloro-3-ethyl-1-methyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)-2-methylpropanoic acid Not in list C17H20ClN3O3 Clc2c(CC)nn(C)c2C(=O)Nc1ccc(cc1)C(C)(C)C(O)=O InChI=1/C17H20ClN3O3/c1-5-12-13(18)14(21(4)20-12)15(22)19-11-8-6-10(7-9-11)17(2,3)16(23)24/h6-9H,5H2,1-4H3,(H,19,22)(H,23,24) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Germany Tebufenpyrad 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad 30Mar2009 2009 doi:10.2903/j.efsa.2009.192r
+Tebufenpyrad 119168-77-3 single chemical entity Component is a metabolite of the substance 2-(4-{[(4-chloro-3-ethyl-1-methyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)-2-methylpropanoic acid 2-(4-{[(4-chloro-3-ethyl-1-methyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)-2-methylpropanoic acid Not in list C17H20ClN3O3 Clc2c(CC)nn(C)c2C(=O)Nc1ccc(cc1)C(C)(C)C(O)=O InChI=1/C17H20ClN3O3/c1-5-12-13(18)14(21(4)20-12)15(22)19-11-8-6-10(7-9-11)17(2,3)16(23)24/h6-9H,5H2,1-4H3,(H,19,22)(H,23,24) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Germany Tebufenpyrad 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad 30Mar2009 2009 doi:10.2903/j.efsa.2009.192r
+Tebufenpyrad 119168-77-3 single chemical entity Component is a metabolite of the substance 4-chloro-3-ethyl-1-methyl-5-pyrazolecarboxamide 4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide Not in list C7H10ClN3O Clc1c(CC)nn(C)c1C(=O)N InChI=1/C7H10ClN3O/c1-3-4-5(8)6(7(9)12)11(2)10-4/h3H2,1-2H3,(H2,9,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany Tebufenpyrad 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad 30Mar2009 2009 doi:10.2903/j.efsa.2009.192r
+Tebufenpyrad 119168-77-3 single chemical entity Component is a metabolite of the substance 4-chloro-3-ethyl-1-methyl-5-pyrazolecarboxamide 4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide Not in list C7H10ClN3O Clc1c(CC)nn(C)c1C(=O)N InChI=1/C7H10ClN3O/c1-3-4-5(8)6(7(9)12)11(2)10-4/h3H2,1-2H3,(H2,9,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany Tebufenpyrad 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad 30Mar2009 2009 doi:10.2903/j.efsa.2009.192r
+Tebufenpyrad 119168-77-3 single chemical entity Component is a metabolite of the substance 4-chloro-3-ethyl-1-methyl-5-pyrazolecarboxamide 4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide Not in list C7H10ClN3O Clc1c(CC)nn(C)c1C(=O)N InChI=1/C7H10ClN3O/c1-3-4-5(8)6(7(9)12)11(2)10-4/h3H2,1-2H3,(H2,9,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Germany Tebufenpyrad 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad 30Mar2009 2009 doi:10.2903/j.efsa.2009.192r
+Tebufenpyrad 119168-77-3 single chemical entity Component is a metabolite of the substance 4-chloro-3-ethyl-1-methyl-5-pyrazolecarboxamide 4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide Not in list C7H10ClN3O Clc1c(CC)nn(C)c1C(=O)N InChI=1/C7H10ClN3O/c1-3-4-5(8)6(7(9)12)11(2)10-4/h3H2,1-2H3,(H2,9,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany Tebufenpyrad 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad 30Mar2009 2009 doi:10.2903/j.efsa.2009.192r
+Tebufenpyrad 119168-77-3 single chemical entity Component is a metabolite of the substance 4-chloro-3-ethyl-1-methyl-5-pyrazolecarboxamide 4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide Not in list C7H10ClN3O Clc1c(CC)nn(C)c1C(=O)N InChI=1/C7H10ClN3O/c1-3-4-5(8)6(7(9)12)11(2)10-4/h3H2,1-2H3,(H2,9,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Germany Tebufenpyrad 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad 30Mar2009 2009 doi:10.2903/j.efsa.2009.192r
+Tebufenpyrad 119168-77-3 single chemical entity Component is a metabolite of the substance 4-chloro-3-ethyl-1-methyl-5-pyrazolecarboxamide 4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide Not in list C7H10ClN3O Clc1c(CC)nn(C)c1C(=O)N InChI=1/C7H10ClN3O/c1-3-4-5(8)6(7(9)12)11(2)10-4/h3H2,1-2H3,(H2,9,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany Tebufenpyrad 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad 30Mar2009 2009 doi:10.2903/j.efsa.2009.192r
+Tebufenpyrad 119168-77-3 single chemical entity Component is a metabolite of the substance 4-chloro-3-ethyl-1-methyl-5-pyrazolecarboxamide 4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide Not in list C7H10ClN3O Clc1c(CC)nn(C)c1C(=O)N InChI=1/C7H10ClN3O/c1-3-4-5(8)6(7(9)12)11(2)10-4/h3H2,1-2H3,(H2,9,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany Tebufenpyrad 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad 30Mar2009 2009 doi:10.2903/j.efsa.2009.192r
+Tebufenpyrad 119168-77-3 single chemical entity Component is a metabolite of the substance 4-chloro-3-ethyl-1-methyl-5-pyrazolecarboxamide 4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide Not in list C7H10ClN3O Clc1c(CC)nn(C)c1C(=O)N InChI=1/C7H10ClN3O/c1-3-4-5(8)6(7(9)12)11(2)10-4/h3H2,1-2H3,(H2,9,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany Tebufenpyrad 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad 30Mar2009 2009 doi:10.2903/j.efsa.2009.192r
+Tebufenpyrad 119168-77-3 single chemical entity Component is a metabolite of the substance 4-chloro-3-ethyl-1-methyl-5-pyrazolecarboxamide 4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide Not in list C7H10ClN3O Clc1c(CC)nn(C)c1C(=O)N InChI=1/C7H10ClN3O/c1-3-4-5(8)6(7(9)12)11(2)10-4/h3H2,1-2H3,(H2,9,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany Tebufenpyrad 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad 30Mar2009 2009 doi:10.2903/j.efsa.2009.192r
+Tebufenpyrad 119168-77-3 single chemical entity Component is a metabolite of the substance 4-chloro-3-ethyl-1-methyl-5-pyrazolecarboxamide 4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide Not in list C7H10ClN3O Clc1c(CC)nn(C)c1C(=O)N InChI=1/C7H10ClN3O/c1-3-4-5(8)6(7(9)12)11(2)10-4/h3H2,1-2H3,(H2,9,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany Tebufenpyrad 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad 30Mar2009 2009 doi:10.2903/j.efsa.2009.192r
+Thiabendazole 205-725-8 148-79-8 single chemical entity Component is identical to the substance Thiabendazole 205-725-8 148-79-8 2-(thiazol-4-yl)benzimidazole Thiabendazole C10H7N3S C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3 InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Spain Thiabendazole (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole 04Nov2014 2014 doi:10.2903/j.efsa.2014.3880
+Thiabendazole 205-725-8 148-79-8 single chemical entity Component is identical to the substance Thiabendazole 205-725-8 148-79-8 2-(thiazol-4-yl)benzimidazole Thiabendazole C10H7N3S C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3 InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Spain Thiabendazole (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole 04Nov2014 2014 doi:10.2903/j.efsa.2014.3880
+Thiabendazole 205-725-8 148-79-8 single chemical entity Component is identical to the substance Thiabendazole 205-725-8 148-79-8 2-(thiazol-4-yl)benzimidazole Thiabendazole C10H7N3S C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3 InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Spain Thiabendazole (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole 04Nov2014 2014 doi:10.2903/j.efsa.2014.3880
+Thiabendazole 205-725-8 148-79-8 single chemical entity Component is identical to the substance Thiabendazole 205-725-8 148-79-8 2-(thiazol-4-yl)benzimidazole Thiabendazole C10H7N3S C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3 InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Spain Thiabendazole (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole 04Nov2014 2014 doi:10.2903/j.efsa.2014.3880
+Thiabendazole 205-725-8 148-79-8 single chemical entity Component is identical to the substance Thiabendazole 205-725-8 148-79-8 2-(thiazol-4-yl)benzimidazole Thiabendazole C10H7N3S C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3 InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Spain Thiabendazole (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole 04Nov2014 2014 doi:10.2903/j.efsa.2014.3880
+Thiabendazole 205-725-8 148-79-8 single chemical entity Component is identical to the substance Thiabendazole 205-725-8 148-79-8 2-(thiazol-4-yl)benzimidazole Thiabendazole C10H7N3S C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3 InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle without Negative RMS: Spain Thiabendazole (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole 04Nov2014 2014 doi:10.2903/j.efsa.2014.3880
+Thiabendazole 205-725-8 148-79-8 single chemical entity Component is identical to the substance Thiabendazole 205-725-8 148-79-8 2-(thiazol-4-yl)benzimidazole Thiabendazole C10H7N3S C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3 InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle with Negative RMS: Spain Thiabendazole (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole 04Nov2014 2014 doi:10.2903/j.efsa.2014.3880
+Thiabendazole 205-725-8 148-79-8 single chemical entity Component is identical to the substance Thiabendazole 205-725-8 148-79-8 2-(thiazol-4-yl)benzimidazole Thiabendazole C10H7N3S C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3 InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Spain Thiabendazole (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole 04Nov2014 2014 doi:10.2903/j.efsa.2014.3880
+Thiabendazole 205-725-8 148-79-8 single chemical entity Component is identical to the substance Thiabendazole 205-725-8 148-79-8 2-(thiazol-4-yl)benzimidazole Thiabendazole C10H7N3S C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3 InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Spain Thiabendazole (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole 04Nov2014 2014 doi:10.2903/j.efsa.2014.3880
+Thiabendazole 205-725-8 148-79-8 single chemical entity Component is identical to the substance Thiabendazole 205-725-8 148-79-8 2-(thiazol-4-yl)benzimidazole Thiabendazole C10H7N3S C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3 InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Spain Thiabendazole (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole 04Nov2014 2014 doi:10.2903/j.efsa.2014.3880
+Thiabendazole 205-725-8 148-79-8 single chemical entity Component is identical to the substance Thiabendazole 205-725-8 148-79-8 2-(thiazol-4-yl)benzimidazole Thiabendazole C10H7N3S C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3 InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Spain Thiabendazole (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole 04Nov2014 2014 doi:10.2903/j.efsa.2014.3880
+Thiabendazole 205-725-8 148-79-8 single chemical entity Component is identical to the substance Thiabendazole 205-725-8 148-79-8 2-(thiazol-4-yl)benzimidazole Thiabendazole C10H7N3S C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3 InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Spain Thiabendazole (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole 04Nov2014 2014 doi:10.2903/j.efsa.2014.3880
+Thiabendazole 205-725-8 148-79-8 single chemical entity Component is identical to the substance Thiabendazole 205-725-8 148-79-8 2-(thiazol-4-yl)benzimidazole Thiabendazole C10H7N3S C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3 InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Spain Thiabendazole (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole 04Nov2014 2014 doi:10.2903/j.efsa.2014.3880
+Thiabendazole 205-725-8 148-79-8 single chemical entity Component is identical to the substance Thiabendazole 205-725-8 148-79-8 2-(thiazol-4-yl)benzimidazole Thiabendazole C10H7N3S C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3 InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Spain Thiabendazole (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole 04Nov2014 2014 doi:10.2903/j.efsa.2014.3880
+Thiabendazole 205-725-8 148-79-8 single chemical entity Component is identical to the substance Thiabendazole 205-725-8 148-79-8 2-(thiazol-4-yl)benzimidazole Thiabendazole C10H7N3S C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3 InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Spain Thiabendazole (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole 04Nov2014 2014 doi:10.2903/j.efsa.2014.3880
+Thiabendazole 205-725-8 148-79-8 single chemical entity Component is identical to the substance Thiabendazole 205-725-8 148-79-8 2-(thiazol-4-yl)benzimidazole Thiabendazole C10H7N3S C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3 InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Spain Thiabendazole (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole 04Nov2014 2014 doi:10.2903/j.efsa.2014.3880
+Thiabendazole 205-725-8 148-79-8 single chemical entity Component is identical to the substance Thiabendazole 205-725-8 148-79-8 2-(thiazol-4-yl)benzimidazole Thiabendazole C10H7N3S C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3 InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity RMS: Spain Thiabendazole (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole 04Nov2014 2014 doi:10.2903/j.efsa.2014.3880
+Thiabendazole 205-725-8 148-79-8 single chemical entity Component is identical to the substance Thiabendazole 205-725-8 148-79-8 2-(thiazol-4-yl)benzimidazole Thiabendazole C10H7N3S C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3 InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity RMS: Spain Thiabendazole (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole 04Nov2014 2014 doi:10.2903/j.efsa.2014.3880
+Thiabendazole 205-725-8 148-79-8 single chemical entity Component is identical to the substance Thiabendazole 205-725-8 148-79-8 2-(thiazol-4-yl)benzimidazole Thiabendazole C10H7N3S C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3 InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 16.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity RMS: Spain Thiabendazole (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole 04Nov2014 2014 doi:10.2903/j.efsa.2014.3880
+Thiodicarb 261-848-7 59669-26-0 single chemical entity Component is identical to the substance Thiodicarb 261-848-7 59669-26-0 Methyl N-[methyl-[methyl-(1-methylsulfanylethylideneamino)oxycarbonylamino] sulfanylcarbamoyl]oxyethanimidothioate Thiodicarb C10H18N4O4S3 CC(=NOC(=O)N(C)SN(C)C(=O)ON=C(C)SC)SC InChI=1S/C10H18N4O4S3/c1-7(19-5)11-17-9(15)13(3)21-14(4)10(16)18-12-8(2)20-6/h1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Positive no information RMS: The United Kingdom Thiodicarb (Final addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance thiodicarb 30Jan2006 2006 doi:10.2903/j.efsa.2006.55r
+Thiodicarb 261-848-7 59669-26-0 single chemical entity Component is identical to the substance Thiodicarb 261-848-7 59669-26-0 Methyl N-[methyl-[methyl-(1-methylsulfanylethylideneamino)oxycarbonylamino] sulfanylcarbamoyl]oxyethanimidothioate Thiodicarb C10H18N4O4S3 CC(=NOC(=O)N(C)SN(C)C(=O)ON=C(C)SC)SC InChI=1S/C10H18N4O4S3/c1-7(19-5)11-17-9(15)13(3)21-14(4)10(16)18-12-8(2)20-6/h1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Positive no information RMS: The United Kingdom Thiodicarb (Final addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance thiodicarb 30Jan2006 2006 doi:10.2903/j.efsa.2006.55r
+Thiodicarb 261-848-7 59669-26-0 single chemical entity Component is identical to the substance Thiodicarb 261-848-7 59669-26-0 Methyl N-[methyl-[methyl-(1-methylsulfanylethylideneamino)oxycarbonylamino] sulfanylcarbamoyl]oxyethanimidothioate Thiodicarb C10H18N4O4S3 CC(=NOC(=O)N(C)SN(C)C(=O)ON=C(C)SC)SC InChI=1S/C10H18N4O4S3/c1-7(19-5)11-17-9(15)13(3)21-14(4)10(16)18-12-8(2)20-6/h1-6H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable House mouse (as animal) CD-1 3 Male oral: gavage 4.0000000000 h no data not applicable Negative RMS: The United Kingdom Thiodicarb (Final addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance thiodicarb 30Jan2006 2006 doi:10.2903/j.efsa.2006.55r
+Thiodicarb 261-848-7 59669-26-0 single chemical entity Component is identical to the substance Thiodicarb 261-848-7 59669-26-0 Methyl N-[methyl-[methyl-(1-methylsulfanylethylideneamino)oxycarbonylamino] sulfanylcarbamoyl]oxyethanimidothioate Thiodicarb C10H18N4O4S3 CC(=NOC(=O)N(C)SN(C)C(=O)ON=C(C)SC)SC InChI=1S/C10H18N4O4S3/c1-7(19-5)11-17-9(15)13(3)21-14(4)10(16)18-12-8(2)20-6/h1-6H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable House mouse (as animal) CD-1 3 Male oral: gavage 14.0000000000 h no data not applicable Negative RMS: The United Kingdom Thiodicarb (Final addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance thiodicarb 30Jan2006 2006 doi:10.2903/j.efsa.2006.55r
+Thiodicarb 261-848-7 59669-26-0 single chemical entity Component is identical to the substance Thiodicarb 261-848-7 59669-26-0 Methyl N-[methyl-[methyl-(1-methylsulfanylethylideneamino)oxycarbonylamino] sulfanylcarbamoyl]oxyethanimidothioate Thiodicarb C10H18N4O4S3 CC(=NOC(=O)N(C)SN(C)C(=O)ON=C(C)SC)SC InChI=1S/C10H18N4O4S3/c1-7(19-5)11-17-9(15)13(3)21-14(4)10(16)18-12-8(2)20-6/h1-6H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CF-1 8 Male/Female Not reported 24.0000000000 h yes not applicable Negative no evidence RMS: The United Kingdom Thiodicarb (Final addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance thiodicarb 30Jan2006 2006 doi:10.2903/j.efsa.2006.55r
+Thiodicarb 261-848-7 59669-26-0 single chemical entity Component is identical to the substance Thiodicarb 261-848-7 59669-26-0 Methyl N-[methyl-[methyl-(1-methylsulfanylethylideneamino)oxycarbonylamino] sulfanylcarbamoyl]oxyethanimidothioate Thiodicarb C10H18N4O4S3 CC(=NOC(=O)N(C)SN(C)C(=O)ON=C(C)SC)SC InChI=1S/C10H18N4O4S3/c1-7(19-5)11-17-9(15)13(3)21-14(4)10(16)18-12-8(2)20-6/h1-6H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) Yes Acceptable Rat (as animal) Fischer344 15 Male oral: feed 56.0000000000 D yes not applicable Negative RMS: The United Kingdom Thiodicarb (Final addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance thiodicarb 30Jan2006 2006 doi:10.2903/j.efsa.2006.55r
+Thymol 201-944-8 89-83-8 single chemical entity Component is identical to the substance Thymol 201-944-8 89-83-8 5-Methyl-2-propan-2-ylphenol Thymol C10H14O CC1=CC(=C(C=C1)C(C)C)O InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The United Kingdom Thymol 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thymol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2916
+Thymol 201-944-8 89-83-8 single chemical entity Component is identical to the substance Thymol 201-944-8 89-83-8 5-Methyl-2-propan-2-ylphenol Thymol C10H14O CC1=CC(=C(C=C1)C(C)C)O InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair SOS/umu test in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) PQ37 Not reported yes no data Positive RMS: The United Kingdom Thymol 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thymol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2916
+Thymol 201-944-8 89-83-8 single chemical entity Component is identical to the substance Thymol 201-944-8 89-83-8 5-Methyl-2-propan-2-ylphenol Thymol C10H14O CC1=CC(=C(C=C1)C(C)C)O InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) WP2 Not reported yes no data Positive RMS: The United Kingdom Thymol 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thymol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2916
+Thymol 201-944-8 89-83-8 single chemical entity Component is identical to the substance Thymol 201-944-8 89-83-8 5-Methyl-2-propan-2-ylphenol Thymol C10H14O CC1=CC(=C(C=C1)C(C)C)O InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The United Kingdom Thymol 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thymol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2916
+Thymol 201-944-8 89-83-8 single chemical entity Component is identical to the substance Thymol 201-944-8 89-83-8 5-Methyl-2-propan-2-ylphenol Thymol C10H14O CC1=CC(=C(C=C1)C(C)C)O InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The United Kingdom Thymol 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thymol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2916
+Thymol 201-944-8 89-83-8 single chemical entity Component is identical to the substance Thymol 201-944-8 89-83-8 5-Methyl-2-propan-2-ylphenol Thymol C10H14O CC1=CC(=C(C=C1)C(C)C)O InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The United Kingdom Thymol 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thymol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2916
+Thymol 201-944-8 89-83-8 single chemical entity Component is identical to the substance Thymol 201-944-8 89-83-8 5-Methyl-2-propan-2-ylphenol Thymol C10H14O CC1=CC(=C(C=C1)C(C)C)O InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thymol 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thymol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2916
+Thymol 201-944-8 89-83-8 single chemical entity Component is identical to the substance Thymol 201-944-8 89-83-8 5-Methyl-2-propan-2-ylphenol Thymol C10H14O CC1=CC(=C(C=C1)C(C)C)O InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thymol 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thymol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2916
+Thymol 201-944-8 89-83-8 single chemical entity Component is identical to the substance Thymol 201-944-8 89-83-8 5-Methyl-2-propan-2-ylphenol Thymol C10H14O CC1=CC(=C(C=C1)C(C)C)O InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thymol 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thymol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2916
+Thymol 201-944-8 89-83-8 single chemical entity Component is identical to the substance Thymol 201-944-8 89-83-8 5-Methyl-2-propan-2-ylphenol Thymol C10H14O CC1=CC(=C(C=C1)C(C)C)O InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thymol 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thymol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2916
+Thymol 201-944-8 89-83-8 single chemical entity Component is identical to the substance Thymol 201-944-8 89-83-8 5-Methyl-2-propan-2-ylphenol Thymol C10H14O CC1=CC(=C(C=C1)C(C)C)O InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thymol 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thymol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2916
+Thymol 201-944-8 89-83-8 single chemical entity Component is identical to the substance Thymol 201-944-8 89-83-8 5-Methyl-2-propan-2-ylphenol Thymol C10H14O CC1=CC(=C(C=C1)C(C)C)O InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thymol 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thymol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2916
+Thymol 201-944-8 89-83-8 single chemical entity Component is identical to the substance Thymol 201-944-8 89-83-8 5-Methyl-2-propan-2-ylphenol Thymol C10H14O CC1=CC(=C(C=C1)C(C)C)O InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The United Kingdom Thymol 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thymol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2916
+Thymol 201-944-8 89-83-8 single chemical entity Component is identical to the substance Thymol 201-944-8 89-83-8 5-Methyl-2-propan-2-ylphenol Thymol C10H14O CC1=CC(=C(C=C1)C(C)C)O InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The United Kingdom Thymol 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thymol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2916
+Thymol 201-944-8 89-83-8 single chemical entity Component is identical to the substance Thymol 201-944-8 89-83-8 5-Methyl-2-propan-2-ylphenol Thymol C10H14O CC1=CC(=C(C=C1)C(C)C)O InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The United Kingdom Thymol 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thymol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2916
+Thymol 201-944-8 89-83-8 single chemical entity Component is identical to the substance Thymol 201-944-8 89-83-8 5-Methyl-2-propan-2-ylphenol Thymol C10H14O CC1=CC(=C(C=C1)C(C)C)O InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The United Kingdom Thymol 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thymol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2916
+Thymol 201-944-8 89-83-8 single chemical entity Component is identical to the substance Thymol 201-944-8 89-83-8 5-Methyl-2-propan-2-ylphenol Thymol C10H14O CC1=CC(=C(C=C1)C(C)C)O InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The United Kingdom Thymol 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thymol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2916
+Thymol 201-944-8 89-83-8 single chemical entity Component is identical to the substance Thymol 201-944-8 89-83-8 5-Methyl-2-propan-2-ylphenol Thymol C10H14O CC1=CC(=C(C=C1)C(C)C)O InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The United Kingdom Thymol 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thymol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2916
+Thymol 201-944-8 89-83-8 single chemical entity Component is identical to the substance Thymol 201-944-8 89-83-8 5-Methyl-2-propan-2-ylphenol Thymol C10H14O CC1=CC(=C(C=C1)C(C)C)O InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The United Kingdom Thymol 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thymol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2916
+Thymol 201-944-8 89-83-8 single chemical entity Component is identical to the substance Thymol 201-944-8 89-83-8 5-Methyl-2-propan-2-ylphenol Thymol C10H14O CC1=CC(=C(C=C1)C(C)C)O InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The United Kingdom Thymol 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thymol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2916
+Thymol 201-944-8 89-83-8 single chemical entity Component is identical to the substance Thymol 201-944-8 89-83-8 5-Methyl-2-propan-2-ylphenol Thymol C10H14O CC1=CC(=C(C=C1)C(C)C)O InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The United Kingdom Thymol 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thymol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2916
+Thymol 201-944-8 89-83-8 single chemical entity Component is identical to the substance Thymol 201-944-8 89-83-8 5-Methyl-2-propan-2-ylphenol Thymol C10H14O CC1=CC(=C(C=C1)C(C)C)O InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The United Kingdom Thymol 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thymol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2916
+Thymol 201-944-8 89-83-8 single chemical entity Component is identical to the substance Thymol 201-944-8 89-83-8 5-Methyl-2-propan-2-ylphenol Thymol C10H14O CC1=CC(=C(C=C1)C(C)C)O InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: The United Kingdom Thymol 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thymol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2916
+Thymol 201-944-8 89-83-8 single chemical entity Component is identical to the substance Thymol 201-944-8 89-83-8 5-Methyl-2-propan-2-ylphenol Thymol C10H14O CC1=CC(=C(C=C1)C(C)C)O InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The United Kingdom Thymol 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thymol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2916
+Thymol 201-944-8 89-83-8 single chemical entity Component is identical to the substance Thymol 201-944-8 89-83-8 5-Methyl-2-propan-2-ylphenol Thymol C10H14O CC1=CC(=C(C=C1)C(C)C)O InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The United Kingdom Thymol 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thymol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2916
+Thymol 201-944-8 89-83-8 single chemical entity Component is identical to the substance Thymol 201-944-8 89-83-8 5-Methyl-2-propan-2-ylphenol Thymol C10H14O CC1=CC(=C(C=C1)C(C)C)O InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The United Kingdom Thymol 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thymol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2916
+Thymol 201-944-8 89-83-8 single chemical entity Component is identical to the substance Thymol 201-944-8 89-83-8 5-Methyl-2-propan-2-ylphenol Thymol C10H14O CC1=CC(=C(C=C1)C(C)C)O InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The United Kingdom Thymol 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thymol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2916
+Thymol 201-944-8 89-83-8 single chemical entity Component is identical to the substance Thymol 201-944-8 89-83-8 5-Methyl-2-propan-2-ylphenol Thymol C10H14O CC1=CC(=C(C=C1)C(C)C)O InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The United Kingdom Thymol 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thymol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2916
+Thymol 201-944-8 89-83-8 single chemical entity Component is identical to the substance Thymol 201-944-8 89-83-8 5-Methyl-2-propan-2-ylphenol Thymol C10H14O CC1=CC(=C(C=C1)C(C)C)O InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The United Kingdom Thymol 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thymol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2916
+Thymol 201-944-8 89-83-8 single chemical entity Component is identical to the substance Thymol 201-944-8 89-83-8 5-Methyl-2-propan-2-ylphenol Thymol C10H14O CC1=CC(=C(C=C1)C(C)C)O InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: The United Kingdom Thymol 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thymol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2916
+Thymol 201-944-8 89-83-8 single chemical entity Component is identical to the substance Thymol 201-944-8 89-83-8 5-Methyl-2-propan-2-ylphenol Thymol C10H14O CC1=CC(=C(C=C1)C(C)C)O InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) embryo cells Not reported yes without Negative RMS: The United Kingdom Thymol 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thymol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2916
+Thymol 201-944-8 89-83-8 single chemical entity Component is identical to the substance Thymol 201-944-8 89-83-8 5-Methyl-2-propan-2-ylphenol Thymol C10H14O CC1=CC(=C(C=C1)C(C)C)O InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) embryo cells Not reported yes with Positive RMS: The United Kingdom Thymol 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thymol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2916
+Thymol 201-944-8 89-83-8 single chemical entity Component is identical to the substance Thymol 201-944-8 89-83-8 5-Methyl-2-propan-2-ylphenol Thymol C10H14O CC1=CC(=C(C=C1)C(C)C)O InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Ambiguous RMS: The United Kingdom Thymol 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thymol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2916
+Thymol 201-944-8 89-83-8 single chemical entity Component is identical to the substance Thymol 201-944-8 89-83-8 5-Methyl-2-propan-2-ylphenol Thymol C10H14O CC1=CC(=C(C=C1)C(C)C)O InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Positive RMS: The United Kingdom Thymol 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thymol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2916
+Thymol 201-944-8 89-83-8 single chemical entity Component is identical to the substance Thymol 201-944-8 89-83-8 5-Methyl-2-propan-2-ylphenol Thymol C10H14O CC1=CC(=C(C=C1)C(C)C)O InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro According to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No Acceptable Human (as organism) lymphocytes Not reported yes without Positive RMS: The United Kingdom Thymol 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thymol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2916
+Thymol 201-944-8 89-83-8 single chemical entity Component is identical to the substance Thymol 201-944-8 89-83-8 5-Methyl-2-propan-2-ylphenol Thymol C10H14O CC1=CC(=C(C=C1)C(C)C)O InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: The United Kingdom Thymol 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thymol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2916
+Thymol 201-944-8 89-83-8 single chemical entity Component is identical to the substance Thymol 201-944-8 89-83-8 5-Methyl-2-propan-2-ylphenol Thymol C10H14O CC1=CC(=C(C=C1)C(C)C)O InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: The United Kingdom Thymol 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thymol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2916
+Thymol 201-944-8 89-83-8 single chemical entity Component is identical to the substance Thymol 201-944-8 89-83-8 5-Methyl-2-propan-2-ylphenol Thymol C10H14O CC1=CC(=C(C=C1)C(C)C)O InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) BDF1 mouse 10 Male/Female oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect-toxicokinetic investigations RMS: The United Kingdom Thymol 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thymol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2916
+Thymol 201-944-8 89-83-8 single chemical entity Component is identical to the substance Thymol 201-944-8 89-83-8 5-Methyl-2-propan-2-ylphenol Thymol C10H14O CC1=CC(=C(C=C1)C(C)C)O InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Sprague-Dawley 4 Male/Female intraperitoneal 24.0000000000 h yes, concurrent vehicle not applicable Positive RMS: The United Kingdom Thymol 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thymol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2916
+Thymol 201-944-8 89-83-8 single chemical entity Component is identical to the substance Thymol 201-944-8 89-83-8 5-Methyl-2-propan-2-ylphenol Thymol C10H14O CC1=CC(=C(C=C1)C(C)C)O InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Sprague-Dawley 4 Male/Female intraperitoneal 12.0000000000 h yes, concurrent vehicle not applicable Positive RMS: The United Kingdom Thymol 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thymol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2916
+Thymol 201-944-8 89-83-8 single chemical entity Component is identical to the substance Thymol 201-944-8 89-83-8 5-Methyl-2-propan-2-ylphenol Thymol C10H14O CC1=CC(=C(C=C1)C(C)C)O InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Sprague-Dawley 4 Male/Female intraperitoneal 6.0000000000 h yes, concurrent vehicle not applicable Positive RMS: The United Kingdom Thymol 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thymol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2916
+Thymol 201-944-8 89-83-8 single chemical entity Component is identical to the substance Thymol 201-944-8 89-83-8 5-Methyl-2-propan-2-ylphenol Thymol C10H14O CC1=CC(=C(C=C1)C(C)C)O InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Rat (as animal) Sprague-Dawley 12 Male/Female oral: gavage 42.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Thymol 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thymol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2916
+Thymol 201-944-8 89-83-8 single chemical entity Component is identical to the substance Thymol 201-944-8 89-83-8 5-Methyl-2-propan-2-ylphenol Thymol C10H14O CC1=CC(=C(C=C1)C(C)C)O InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Rat (as animal) Sprague-Dawley 12 Male/Female oral: gavage 16.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Thymol 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thymol 05Nov2012 2012 doi:10.2903/j.efsa.2012.2916
+Tolclofos-methyl 260-515-3 57018-04-9 single chemical entity Component is identical to the substance Tolclofos-methyl 260-515-3 57018-04-9 O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate Tolclofos-methyl C9H11Cl2O3PS S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Sweden Tolclofos-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl 18Aug2005 2005 doi:10.2903/j.efsa.2005.32ar
+Tolclofos-methyl 260-515-3 57018-04-9 single chemical entity Component is identical to the substance Tolclofos-methyl 260-515-3 57018-04-9 O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate Tolclofos-methyl C9H11Cl2O3PS S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Sweden Tolclofos-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl 18Aug2005 2005 doi:10.2903/j.efsa.2005.32ar
+Tolclofos-methyl 260-515-3 57018-04-9 single chemical entity Component is identical to the substance Tolclofos-methyl 260-515-3 57018-04-9 O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate Tolclofos-methyl C9H11Cl2O3PS S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Sweden Tolclofos-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl 18Aug2005 2005 doi:10.2903/j.efsa.2005.32ar
+Tolclofos-methyl 260-515-3 57018-04-9 single chemical entity Component is identical to the substance Tolclofos-methyl 260-515-3 57018-04-9 O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate Tolclofos-methyl C9H11Cl2O3PS S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Sweden Tolclofos-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl 18Aug2005 2005 doi:10.2903/j.efsa.2005.32ar
+Tolclofos-methyl 260-515-3 57018-04-9 single chemical entity Component is identical to the substance Tolclofos-methyl 260-515-3 57018-04-9 O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate Tolclofos-methyl C9H11Cl2O3PS S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3 organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes, concurrent vehicle no data Negative RMS: Sweden Tolclofos-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl 18Aug2005 2005 doi:10.2903/j.efsa.2005.32ar
+Tolclofos-methyl 260-515-3 57018-04-9 single chemical entity Component is identical to the substance Tolclofos-methyl 260-515-3 57018-04-9 O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate Tolclofos-methyl C9H11Cl2O3PS S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Sweden Tolclofos-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl 18Aug2005 2005 doi:10.2903/j.efsa.2005.32ar
+Tolclofos-methyl 260-515-3 57018-04-9 single chemical entity Component is identical to the substance Tolclofos-methyl 260-515-3 57018-04-9 O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate Tolclofos-methyl C9H11Cl2O3PS S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Sweden Tolclofos-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl 18Aug2005 2005 doi:10.2903/j.efsa.2005.32ar
+Tolclofos-methyl 260-515-3 57018-04-9 single chemical entity Component is identical to the substance Tolclofos-methyl 260-515-3 57018-04-9 O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate Tolclofos-methyl C9H11Cl2O3PS S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Sweden Tolclofos-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl 18Aug2005 2005 doi:10.2903/j.efsa.2005.32ar
+Tolclofos-methyl 260-515-3 57018-04-9 single chemical entity Component is identical to the substance Tolclofos-methyl 260-515-3 57018-04-9 O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate Tolclofos-methyl C9H11Cl2O3PS S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3 organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes, concurrent vehicle no data Negative RMS: Sweden Tolclofos-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl 18Aug2005 2005 doi:10.2903/j.efsa.2005.32ar
+Tolclofos-methyl 260-515-3 57018-04-9 single chemical entity Component is identical to the substance Tolclofos-methyl 260-515-3 57018-04-9 O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate Tolclofos-methyl C9H11Cl2O3PS S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Sweden Tolclofos-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl 18Aug2005 2005 doi:10.2903/j.efsa.2005.32ar
+Tolclofos-methyl 260-515-3 57018-04-9 single chemical entity Component is identical to the substance Tolclofos-methyl 260-515-3 57018-04-9 O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate Tolclofos-methyl C9H11Cl2O3PS S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Sweden Tolclofos-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl 18Aug2005 2005 doi:10.2903/j.efsa.2005.32ar
+Tolclofos-methyl 260-515-3 57018-04-9 single chemical entity Component is identical to the substance Tolclofos-methyl 260-515-3 57018-04-9 O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate Tolclofos-methyl C9H11Cl2O3PS S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Sweden Tolclofos-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl 18Aug2005 2005 doi:10.2903/j.efsa.2005.32ar
+Tolclofos-methyl 260-515-3 57018-04-9 single chemical entity Component is identical to the substance Tolclofos-methyl 260-515-3 57018-04-9 O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate Tolclofos-methyl C9H11Cl2O3PS S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Sweden Tolclofos-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl 18Aug2005 2005 doi:10.2903/j.efsa.2005.32ar
+Tolclofos-methyl 260-515-3 57018-04-9 single chemical entity Component is identical to the substance Tolclofos-methyl 260-515-3 57018-04-9 O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate Tolclofos-methyl C9H11Cl2O3PS S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Sweden Tolclofos-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl 18Aug2005 2005 doi:10.2903/j.efsa.2005.32ar
+Tolclofos-methyl 260-515-3 57018-04-9 single chemical entity Component is identical to the substance Tolclofos-methyl 260-515-3 57018-04-9 O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate Tolclofos-methyl C9H11Cl2O3PS S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3 organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes, concurrent vehicle no data Negative RMS: Sweden Tolclofos-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl 18Aug2005 2005 doi:10.2903/j.efsa.2005.32ar
+Tolclofos-methyl 260-515-3 57018-04-9 single chemical entity Component is identical to the substance Tolclofos-methyl 260-515-3 57018-04-9 O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate Tolclofos-methyl C9H11Cl2O3PS S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Sweden Tolclofos-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl 18Aug2005 2005 doi:10.2903/j.efsa.2005.32ar
+Tolclofos-methyl 260-515-3 57018-04-9 single chemical entity Component is identical to the substance Tolclofos-methyl 260-515-3 57018-04-9 O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate Tolclofos-methyl C9H11Cl2O3PS S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Sweden Tolclofos-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl 18Aug2005 2005 doi:10.2903/j.efsa.2005.32ar
+Tolclofos-methyl 260-515-3 57018-04-9 single chemical entity Component is identical to the substance Tolclofos-methyl 260-515-3 57018-04-9 O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate Tolclofos-methyl C9H11Cl2O3PS S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Sweden Tolclofos-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl 18Aug2005 2005 doi:10.2903/j.efsa.2005.32ar
+Tolclofos-methyl 260-515-3 57018-04-9 single chemical entity Component is identical to the substance Tolclofos-methyl 260-515-3 57018-04-9 O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate Tolclofos-methyl C9H11Cl2O3PS S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Sweden Tolclofos-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl 18Aug2005 2005 doi:10.2903/j.efsa.2005.32ar
+Tolclofos-methyl 260-515-3 57018-04-9 single chemical entity Component is identical to the substance Tolclofos-methyl 260-515-3 57018-04-9 O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate Tolclofos-methyl C9H11Cl2O3PS S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Sweden Tolclofos-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl 18Aug2005 2005 doi:10.2903/j.efsa.2005.32ar
+Tolclofos-methyl 260-515-3 57018-04-9 single chemical entity Component is identical to the substance Tolclofos-methyl 260-515-3 57018-04-9 O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate Tolclofos-methyl C9H11Cl2O3PS S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Sweden Tolclofos-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl 18Aug2005 2005 doi:10.2903/j.efsa.2005.32ar
+Tolclofos-methyl 260-515-3 57018-04-9 single chemical entity Component is identical to the substance Tolclofos-methyl 260-515-3 57018-04-9 O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate Tolclofos-methyl C9H11Cl2O3PS S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3 organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes, concurrent vehicle no data Negative RMS: Sweden Tolclofos-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl 18Aug2005 2005 doi:10.2903/j.efsa.2005.32ar
+Tolclofos-methyl 260-515-3 57018-04-9 single chemical entity Component is identical to the substance Tolclofos-methyl 260-515-3 57018-04-9 O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate Tolclofos-methyl C9H11Cl2O3PS S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Sweden Tolclofos-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl 18Aug2005 2005 doi:10.2903/j.efsa.2005.32ar
+Tolclofos-methyl 260-515-3 57018-04-9 single chemical entity Component is identical to the substance Tolclofos-methyl 260-515-3 57018-04-9 O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate Tolclofos-methyl C9H11Cl2O3PS S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Sweden Tolclofos-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl 18Aug2005 2005 doi:10.2903/j.efsa.2005.32ar
+Tolclofos-methyl 260-515-3 57018-04-9 single chemical entity Component is identical to the substance Tolclofos-methyl 260-515-3 57018-04-9 O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate Tolclofos-methyl C9H11Cl2O3PS S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Sweden Tolclofos-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl 18Aug2005 2005 doi:10.2903/j.efsa.2005.32ar
+Tolclofos-methyl 260-515-3 57018-04-9 single chemical entity Component is identical to the substance Tolclofos-methyl 260-515-3 57018-04-9 O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate Tolclofos-methyl C9H11Cl2O3PS S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Sweden Tolclofos-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl 18Aug2005 2005 doi:10.2903/j.efsa.2005.32ar
+Tolclofos-methyl 260-515-3 57018-04-9 single chemical entity Component is identical to the substance Tolclofos-methyl 260-515-3 57018-04-9 O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate Tolclofos-methyl C9H11Cl2O3PS S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: Sweden Tolclofos-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl 18Aug2005 2005 doi:10.2903/j.efsa.2005.32ar
+Tolclofos-methyl 260-515-3 57018-04-9 single chemical entity Component is identical to the substance Tolclofos-methyl 260-515-3 57018-04-9 O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate Tolclofos-methyl C9H11Cl2O3PS S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: Sweden Tolclofos-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl 18Aug2005 2005 doi:10.2903/j.efsa.2005.32ar
+Tolclofos-methyl 260-515-3 57018-04-9 single chemical entity Component is identical to the substance Tolclofos-methyl 260-515-3 57018-04-9 O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate Tolclofos-methyl C9H11Cl2O3PS S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3 organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Human (as organism) HeLa cells Not reported yes, concurrent vehicle without Negative RMS: Sweden Tolclofos-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl 18Aug2005 2005 doi:10.2903/j.efsa.2005.32ar
+Tolclofos-methyl 260-515-3 57018-04-9 single chemical entity Component is identical to the substance Tolclofos-methyl 260-515-3 57018-04-9 O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate Tolclofos-methyl C9H11Cl2O3PS S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: Sweden Tolclofos-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl 18Aug2005 2005 doi:10.2903/j.efsa.2005.32ar
+Tolclofos-methyl 260-515-3 57018-04-9 single chemical entity Component is identical to the substance Tolclofos-methyl 260-515-3 57018-04-9 O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate Tolclofos-methyl C9H11Cl2O3PS S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Negative RMS: Sweden Tolclofos-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl 18Aug2005 2005 doi:10.2903/j.efsa.2005.32ar
+Tolclofos-methyl 260-515-3 57018-04-9 single chemical entity Component is identical to the substance Tolclofos-methyl 260-515-3 57018-04-9 O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate Tolclofos-methyl C9H11Cl2O3PS S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3 organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Human (as organism) HeLa cells Not reported yes, concurrent vehicle with Negative RMS: Sweden Tolclofos-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl 18Aug2005 2005 doi:10.2903/j.efsa.2005.32ar
+Tolclofos-methyl 260-515-3 57018-04-9 single chemical entity Component is identical to the substance Tolclofos-methyl 260-515-3 57018-04-9 O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate Tolclofos-methyl C9H11Cl2O3PS S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3 organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Sweden Tolclofos-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl 18Aug2005 2005 doi:10.2903/j.efsa.2005.32ar
+Tolclofos-methyl 260-515-3 57018-04-9 single chemical entity Component is identical to the substance Tolclofos-methyl 260-515-3 57018-04-9 O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate Tolclofos-methyl C9H11Cl2O3PS S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) ICR 6 Male intraperitoneal 48.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Sweden Tolclofos-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl 18Aug2005 2005 doi:10.2903/j.efsa.2005.32ar
+Tolclofos-methyl 260-515-3 57018-04-9 single chemical entity Component is identical to the substance Tolclofos-methyl 260-515-3 57018-04-9 O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate Tolclofos-methyl C9H11Cl2O3PS S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) ICR 6 Male intraperitoneal 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Sweden Tolclofos-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl 18Aug2005 2005 doi:10.2903/j.efsa.2005.32ar
+Tolclofos-methyl 260-515-3 57018-04-9 single chemical entity Component is identical to the substance Tolclofos-methyl 260-515-3 57018-04-9 O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate Tolclofos-methyl C9H11Cl2O3PS S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) ICR 6 Male intraperitoneal 6.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Sweden Tolclofos-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl 18Aug2005 2005 doi:10.2903/j.efsa.2005.32ar
+Tolclofos-methyl 260-515-3 57018-04-9 single chemical entity Component is identical to the substance Tolclofos-methyl 260-515-3 57018-04-9 O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate Tolclofos-methyl C9H11Cl2O3PS S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3 organic compound Other Other chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) Yes Acceptable Rat (as animal) Sprague-Dawley 10 Male intraperitoneal 7.0000000000 week yes, historical not applicable Negative RMS: Sweden Tolclofos-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl 18Aug2005 2005 doi:10.2903/j.efsa.2005.32ar
+Topramezone 606-699-4 210631-68-8 single chemical entity Component is identical to the substance Topramezone 606-699-4 210631-68-8 4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one Topramezone (BAS 670H) C16H17N3O5S CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: France Topramezone (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone 03Feb2014 2014 doi:10.2903/j.efsa.2014.3540
+Topramezone 606-699-4 210631-68-8 single chemical entity Component is identical to the substance Topramezone 606-699-4 210631-68-8 4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one Topramezone (BAS 670H) C16H17N3O5S CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: France Topramezone (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone 03Feb2014 2014 doi:10.2903/j.efsa.2014.3540
+Topramezone 606-699-4 210631-68-8 single chemical entity Component is identical to the substance Topramezone 606-699-4 210631-68-8 4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one Topramezone (BAS 670H) C16H17N3O5S CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: France Topramezone (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone 03Feb2014 2014 doi:10.2903/j.efsa.2014.3540
+Topramezone 606-699-4 210631-68-8 single chemical entity Component is identical to the substance Topramezone 606-699-4 210631-68-8 4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one Topramezone (BAS 670H) C16H17N3O5S CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: France Topramezone (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone 03Feb2014 2014 doi:10.2903/j.efsa.2014.3540
+Topramezone 606-699-4 210631-68-8 single chemical entity Component is identical to the substance Topramezone 606-699-4 210631-68-8 4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one Topramezone (BAS 670H) C16H17N3O5S CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: France Topramezone (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone 03Feb2014 2014 doi:10.2903/j.efsa.2014.3540
+Topramezone 606-699-4 210631-68-8 single chemical entity Component is identical to the substance Topramezone 606-699-4 210631-68-8 4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one Topramezone (BAS 670H) C16H17N3O5S CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: France Topramezone (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone 03Feb2014 2014 doi:10.2903/j.efsa.2014.3540
+Topramezone 606-699-4 210631-68-8 single chemical entity Component is identical to the substance Topramezone 606-699-4 210631-68-8 4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one Topramezone (BAS 670H) C16H17N3O5S CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: France Topramezone (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone 03Feb2014 2014 doi:10.2903/j.efsa.2014.3540
+Topramezone 606-699-4 210631-68-8 single chemical entity Component is identical to the substance Topramezone 606-699-4 210631-68-8 4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one Topramezone (BAS 670H) C16H17N3O5S CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: France Topramezone (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone 03Feb2014 2014 doi:10.2903/j.efsa.2014.3540
+Topramezone 606-699-4 210631-68-8 single chemical entity Component is identical to the substance Topramezone 606-699-4 210631-68-8 4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one Topramezone (BAS 670H) C16H17N3O5S CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: France Topramezone (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone 03Feb2014 2014 doi:10.2903/j.efsa.2014.3540
+Topramezone 606-699-4 210631-68-8 single chemical entity Component is identical to the substance Topramezone 606-699-4 210631-68-8 4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one Topramezone (BAS 670H) C16H17N3O5S CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: France Topramezone (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone 03Feb2014 2014 doi:10.2903/j.efsa.2014.3540
+Topramezone 606-699-4 210631-68-8 single chemical entity Component is identical to the substance Topramezone 606-699-4 210631-68-8 4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one Topramezone (BAS 670H) C16H17N3O5S CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: France Topramezone (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone 03Feb2014 2014 doi:10.2903/j.efsa.2014.3540
+Topramezone 606-699-4 210631-68-8 single chemical entity Component is identical to the substance Topramezone 606-699-4 210631-68-8 4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one Topramezone (BAS 670H) C16H17N3O5S CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: France Topramezone (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone 03Feb2014 2014 doi:10.2903/j.efsa.2014.3540
+Topramezone 606-699-4 210631-68-8 single chemical entity Component is identical to the substance Topramezone 606-699-4 210631-68-8 4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one Topramezone (BAS 670H) C16H17N3O5S CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: France Topramezone (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone 03Feb2014 2014 doi:10.2903/j.efsa.2014.3540
+Topramezone 606-699-4 210631-68-8 single chemical entity Component is identical to the substance Topramezone 606-699-4 210631-68-8 4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one Topramezone (BAS 670H) C16H17N3O5S CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: France Topramezone (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone 03Feb2014 2014 doi:10.2903/j.efsa.2014.3540
+Topramezone 606-699-4 210631-68-8 single chemical entity Component is identical to the substance Topramezone 606-699-4 210631-68-8 4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one Topramezone (BAS 670H) C16H17N3O5S CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: France Topramezone (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone 03Feb2014 2014 doi:10.2903/j.efsa.2014.3540
+Topramezone 606-699-4 210631-68-8 single chemical entity Component is identical to the substance Topramezone 606-699-4 210631-68-8 4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one Topramezone (BAS 670H) C16H17N3O5S CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: France Topramezone (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone 03Feb2014 2014 doi:10.2903/j.efsa.2014.3540
+Topramezone 606-699-4 210631-68-8 single chemical entity Component is identical to the substance Topramezone 606-699-4 210631-68-8 4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one Topramezone (BAS 670H) C16H17N3O5S CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: France Topramezone (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone 03Feb2014 2014 doi:10.2903/j.efsa.2014.3540
+Topramezone 606-699-4 210631-68-8 single chemical entity Component is identical to the substance Topramezone 606-699-4 210631-68-8 4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one Topramezone (BAS 670H) C16H17N3O5S CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: France Topramezone (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone 03Feb2014 2014 doi:10.2903/j.efsa.2014.3540
+Topramezone 606-699-4 210631-68-8 single chemical entity Component is identical to the substance Topramezone 606-699-4 210631-68-8 4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one Topramezone (BAS 670H) C16H17N3O5S CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: France Topramezone (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone 03Feb2014 2014 doi:10.2903/j.efsa.2014.3540
+Topramezone 606-699-4 210631-68-8 single chemical entity Component is identical to the substance Topramezone 606-699-4 210631-68-8 4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one Topramezone (BAS 670H) C16H17N3O5S CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: France Topramezone (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone 03Feb2014 2014 doi:10.2903/j.efsa.2014.3540
+Topramezone 606-699-4 210631-68-8 single chemical entity Component is identical to the substance Topramezone 606-699-4 210631-68-8 4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one Topramezone (BAS 670H) C16H17N3O5S CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: France Topramezone (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone 03Feb2014 2014 doi:10.2903/j.efsa.2014.3540
+Topramezone 606-699-4 210631-68-8 single chemical entity Component is identical to the substance Topramezone 606-699-4 210631-68-8 4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one Topramezone (BAS 670H) C16H17N3O5S CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: France Topramezone (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone 03Feb2014 2014 doi:10.2903/j.efsa.2014.3540
+Topramezone 606-699-4 210631-68-8 single chemical entity Component is identical to the substance Topramezone 606-699-4 210631-68-8 4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one Topramezone (BAS 670H) C16H17N3O5S CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: France Topramezone (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone 03Feb2014 2014 doi:10.2903/j.efsa.2014.3540
+Topramezone 606-699-4 210631-68-8 single chemical entity Component is identical to the substance Topramezone 606-699-4 210631-68-8 4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one Topramezone (BAS 670H) C16H17N3O5S CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Positive RMS: France Topramezone (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone 03Feb2014 2014 doi:10.2903/j.efsa.2014.3540
+Topramezone 606-699-4 210631-68-8 single chemical entity Component is identical to the substance Topramezone 606-699-4 210631-68-8 4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one Topramezone (BAS 670H) C16H17N3O5S CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: France Topramezone (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone 03Feb2014 2014 doi:10.2903/j.efsa.2014.3540
+Topramezone 606-699-4 210631-68-8 single chemical entity Component is identical to the substance Topramezone 606-699-4 210631-68-8 4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one Topramezone (BAS 670H) C16H17N3O5S CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: France Topramezone (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone 03Feb2014 2014 doi:10.2903/j.efsa.2014.3540
+Topramezone 606-699-4 210631-68-8 single chemical entity Component is identical to the substance Topramezone 606-699-4 210631-68-8 4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one Topramezone (BAS 670H) C16H17N3O5S CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: France Topramezone (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone 03Feb2014 2014 doi:10.2903/j.efsa.2014.3540
+Topramezone 606-699-4 210631-68-8 single chemical entity Component is identical to the substance Topramezone 606-699-4 210631-68-8 4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one Topramezone (BAS 670H) C16H17N3O5S CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: France Topramezone (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone 03Feb2014 2014 doi:10.2903/j.efsa.2014.3540
+Topramezone 606-699-4 210631-68-8 single chemical entity Component is identical to the substance Topramezone 606-699-4 210631-68-8 4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one Topramezone (BAS 670H) C16H17N3O5S CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: France Topramezone (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone 03Feb2014 2014 doi:10.2903/j.efsa.2014.3540
+Topramezone 606-699-4 210631-68-8 single chemical entity Component is identical to the substance Topramezone 606-699-4 210631-68-8 4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one Topramezone (BAS 670H) C16H17N3O5S CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: France Topramezone (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone 03Feb2014 2014 doi:10.2903/j.efsa.2014.3540
+Topramezone 606-699-4 210631-68-8 single chemical entity Component is identical to the substance Topramezone 606-699-4 210631-68-8 4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one Topramezone (BAS 670H) C16H17N3O5S CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: France Topramezone (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone 03Feb2014 2014 doi:10.2903/j.efsa.2014.3540
+Topramezone 606-699-4 210631-68-8 single chemical entity Component is identical to the substance Topramezone 606-699-4 210631-68-8 4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one Topramezone (BAS 670H) C16H17N3O5S CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: France Topramezone (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone 03Feb2014 2014 doi:10.2903/j.efsa.2014.3540
+Topramezone 606-699-4 210631-68-8 single chemical entity Component is identical to the substance Topramezone 606-699-4 210631-68-8 4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one Topramezone (BAS 670H) C16H17N3O5S CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: France Topramezone (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone 03Feb2014 2014 doi:10.2903/j.efsa.2014.3540
+Topramezone 606-699-4 210631-68-8 single chemical entity Component is identical to the substance Topramezone 606-699-4 210631-68-8 4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one Topramezone (BAS 670H) C16H17N3O5S CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: France Topramezone (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone 03Feb2014 2014 doi:10.2903/j.efsa.2014.3540
+Topramezone 606-699-4 210631-68-8 single chemical entity Component is identical to the substance Topramezone 606-699-4 210631-68-8 4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one Topramezone (BAS 670H) C16H17N3O5S CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: France Topramezone (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone 03Feb2014 2014 doi:10.2903/j.efsa.2014.3540
+Topramezone 606-699-4 210631-68-8 single chemical entity Component is identical to the substance Topramezone 606-699-4 210631-68-8 4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one Topramezone (BAS 670H) C16H17N3O5S CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: France Topramezone (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone 03Feb2014 2014 doi:10.2903/j.efsa.2014.3540
+Topramezone 606-699-4 210631-68-8 single chemical entity Component is identical to the substance Topramezone 606-699-4 210631-68-8 4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one Topramezone (BAS 670H) C16H17N3O5S CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: France Topramezone (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone 03Feb2014 2014 doi:10.2903/j.efsa.2014.3540
+Topramezone 606-699-4 210631-68-8 single chemical entity Component is identical to the substance Topramezone 606-699-4 210631-68-8 4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one Topramezone (BAS 670H) C16H17N3O5S CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: France Topramezone (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone 03Feb2014 2014 doi:10.2903/j.efsa.2014.3540
+Topramezone 606-699-4 210631-68-8 single chemical entity Component is identical to the substance Topramezone 606-699-4 210631-68-8 4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one Topramezone (BAS 670H) C16H17N3O5S CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: France Topramezone (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone 03Feb2014 2014 doi:10.2903/j.efsa.2014.3540
+Topramezone 606-699-4 210631-68-8 single chemical entity Component is identical to the substance Topramezone 606-699-4 210631-68-8 4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one Topramezone (BAS 670H) C16H17N3O5S CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: France Topramezone (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone 03Feb2014 2014 doi:10.2903/j.efsa.2014.3540
+Topramezone 606-699-4 210631-68-8 single chemical entity Component is identical to the substance Topramezone 606-699-4 210631-68-8 4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one Topramezone (BAS 670H) C16H17N3O5S CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: France Topramezone (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone 03Feb2014 2014 doi:10.2903/j.efsa.2014.3540
+Topramezone 606-699-4 210631-68-8 single chemical entity Component is identical to the substance Topramezone 606-699-4 210631-68-8 4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one Topramezone (BAS 670H) C16H17N3O5S CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: France Topramezone (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone 03Feb2014 2014 doi:10.2903/j.efsa.2014.3540
+Topramezone 606-699-4 210631-68-8 single chemical entity Component is identical to the substance Topramezone 606-699-4 210631-68-8 4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one Topramezone (BAS 670H) C16H17N3O5S CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Positive RMS: France Topramezone (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone 03Feb2014 2014 doi:10.2903/j.efsa.2014.3540
+Topramezone 606-699-4 210631-68-8 single chemical entity Component is identical to the substance Topramezone 606-699-4 210631-68-8 4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one Topramezone (BAS 670H) C16H17N3O5S CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: France Topramezone (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone 03Feb2014 2014 doi:10.2903/j.efsa.2014.3540
+Topramezone 606-699-4 210631-68-8 single chemical entity Component is identical to the substance Topramezone 606-699-4 210631-68-8 4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one Topramezone (BAS 670H) C16H17N3O5S CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Positive RMS: France Topramezone (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone 03Feb2014 2014 doi:10.2903/j.efsa.2014.3540
+Topramezone 606-699-4 210631-68-8 single chemical entity Component is identical to the substance Topramezone 606-699-4 210631-68-8 4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one Topramezone (BAS 670H) C16H17N3O5S CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: France Topramezone (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone 03Feb2014 2014 doi:10.2903/j.efsa.2014.3540
+Topramezone 606-699-4 210631-68-8 single chemical entity Component is identical to the substance Topramezone 606-699-4 210631-68-8 4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one Topramezone (BAS 670H) C16H17N3O5S CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: France Topramezone (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone 03Feb2014 2014 doi:10.2903/j.efsa.2014.3540
+Topramezone 606-699-4 210631-68-8 single chemical entity Component is identical to the substance Topramezone 606-699-4 210631-68-8 4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one Topramezone (BAS 670H) C16H17N3O5S CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI Male intraperitoneal 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: France Topramezone (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone 03Feb2014 2014 doi:10.2903/j.efsa.2014.3540
+Topramezone 606-699-4 210631-68-8 single chemical entity Component is identical to the substance Topramezone 606-699-4 210631-68-8 4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one Topramezone (BAS 670H) C16H17N3O5S CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Wistar 3 Male oral: gavage 3.0000000000 h yes, concurrent vehicle not applicable Negative RMS: France Topramezone (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone 03Feb2014 2014 doi:10.2903/j.efsa.2014.3540
+Topramezone 606-699-4 210631-68-8 single chemical entity Component is identical to the substance Topramezone 606-699-4 210631-68-8 4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one Topramezone (BAS 670H) C16H17N3O5S CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Wistar 3 Male oral: gavage 14.0000000000 h yes, concurrent vehicle not applicable Negative RMS: France Topramezone (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone 03Feb2014 2014 doi:10.2903/j.efsa.2014.3540
+Topramezone 606-699-4 210631-68-8 single chemical entity Component is a metabolite of the substance 3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-(methylsulfonyl)benzoic acid 3-(4,5-dihydroisoxazol-3-yl)-2-methyl-4-(methylsulfonyl)benzoic acid Not in list C12H13NO5S CS(=O)(=O)c2ccc(c(C)c2C=1CCON=1)C(O)=O InChI=1/C12H13NO5S/c1-7-8(12(14)15)3-4-10(19(2,16)17)11(7)9-5-6-18-13-9/h3-4H,5-6H2,1-2H3,(H,14,15) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: France Topramezone (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone 03Feb2014 2014 doi:10.2903/j.efsa.2014.3540
+Topramezone 606-699-4 210631-68-8 single chemical entity Component is a metabolite of the substance 3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-(methylsulfonyl)benzoic acid 3-(4,5-dihydroisoxazol-3-yl)-2-methyl-4-(methylsulfonyl)benzoic acid Not in list C12H13NO5S CS(=O)(=O)c2ccc(c(C)c2C=1CCON=1)C(O)=O InChI=1/C12H13NO5S/c1-7-8(12(14)15)3-4-10(19(2,16)17)11(7)9-5-6-18-13-9/h3-4H,5-6H2,1-2H3,(H,14,15) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Negative RMS: France Topramezone (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone 03Feb2014 2014 doi:10.2903/j.efsa.2014.3540
+Topramezone 606-699-4 210631-68-8 single chemical entity Component is a metabolite of the substance 3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-(methylsulfonyl)benzoic acid 3-(4,5-dihydroisoxazol-3-yl)-2-methyl-4-(methylsulfonyl)benzoic acid Not in list C12H13NO5S CS(=O)(=O)c2ccc(c(C)c2C=1CCON=1)C(O)=O InChI=1/C12H13NO5S/c1-7-8(12(14)15)3-4-10(19(2,16)17)11(7)9-5-6-18-13-9/h3-4H,5-6H2,1-2H3,(H,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: France Topramezone (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone 03Feb2014 2014 doi:10.2903/j.efsa.2014.3540
+Topramezone 606-699-4 210631-68-8 single chemical entity Component is a metabolite of the substance 3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-(methylsulfonyl)benzoic acid 3-(4,5-dihydroisoxazol-3-yl)-2-methyl-4-(methylsulfonyl)benzoic acid Not in list C12H13NO5S CS(=O)(=O)c2ccc(c(C)c2C=1CCON=1)C(O)=O InChI=1/C12H13NO5S/c1-7-8(12(14)15)3-4-10(19(2,16)17)11(7)9-5-6-18-13-9/h3-4H,5-6H2,1-2H3,(H,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: France Topramezone (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone 03Feb2014 2014 doi:10.2903/j.efsa.2014.3540
+Topramezone 606-699-4 210631-68-8 single chemical entity Component is a metabolite of the substance 3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-(methylsulfonyl)benzoic acid 3-(4,5-dihydroisoxazol-3-yl)-2-methyl-4-(methylsulfonyl)benzoic acid Not in list C12H13NO5S CS(=O)(=O)c2ccc(c(C)c2C=1CCON=1)C(O)=O InChI=1/C12H13NO5S/c1-7-8(12(14)15)3-4-10(19(2,16)17)11(7)9-5-6-18-13-9/h3-4H,5-6H2,1-2H3,(H,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: France Topramezone (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone 03Feb2014 2014 doi:10.2903/j.efsa.2014.3540
+Topramezone 606-699-4 210631-68-8 single chemical entity Component is a metabolite of the substance 3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-(methylsulfonyl)benzoic acid 3-(4,5-dihydroisoxazol-3-yl)-2-methyl-4-(methylsulfonyl)benzoic acid Not in list C12H13NO5S CS(=O)(=O)c2ccc(c(C)c2C=1CCON=1)C(O)=O InChI=1/C12H13NO5S/c1-7-8(12(14)15)3-4-10(19(2,16)17)11(7)9-5-6-18-13-9/h3-4H,5-6H2,1-2H3,(H,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: France Topramezone (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone 03Feb2014 2014 doi:10.2903/j.efsa.2014.3540
+Topramezone 606-699-4 210631-68-8 single chemical entity Component is a metabolite of the substance 3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-(methylsulfonyl)benzoic acid 3-(4,5-dihydroisoxazol-3-yl)-2-methyl-4-(methylsulfonyl)benzoic acid Not in list C12H13NO5S CS(=O)(=O)c2ccc(c(C)c2C=1CCON=1)C(O)=O InChI=1/C12H13NO5S/c1-7-8(12(14)15)3-4-10(19(2,16)17)11(7)9-5-6-18-13-9/h3-4H,5-6H2,1-2H3,(H,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: France Topramezone (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone 03Feb2014 2014 doi:10.2903/j.efsa.2014.3540
+Topramezone 606-699-4 210631-68-8 single chemical entity Component is a metabolite of the substance 3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-(methylsulfonyl)benzoic acid 3-(4,5-dihydroisoxazol-3-yl)-2-methyl-4-(methylsulfonyl)benzoic acid Not in list C12H13NO5S CS(=O)(=O)c2ccc(c(C)c2C=1CCON=1)C(O)=O InChI=1/C12H13NO5S/c1-7-8(12(14)15)3-4-10(19(2,16)17)11(7)9-5-6-18-13-9/h3-4H,5-6H2,1-2H3,(H,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: France Topramezone (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone 03Feb2014 2014 doi:10.2903/j.efsa.2014.3540
+Topramezone 606-699-4 210631-68-8 single chemical entity Component is a metabolite of the substance 3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-(methylsulfonyl)benzoic acid 3-(4,5-dihydroisoxazol-3-yl)-2-methyl-4-(methylsulfonyl)benzoic acid Not in list C12H13NO5S CS(=O)(=O)c2ccc(c(C)c2C=1CCON=1)C(O)=O InChI=1/C12H13NO5S/c1-7-8(12(14)15)3-4-10(19(2,16)17)11(7)9-5-6-18-13-9/h3-4H,5-6H2,1-2H3,(H,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: France Topramezone (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone 03Feb2014 2014 doi:10.2903/j.efsa.2014.3540
+Topramezone 606-699-4 210631-68-8 single chemical entity Component is a metabolite of the substance 3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-(methylsulfonyl)benzoic acid 3-(4,5-dihydroisoxazol-3-yl)-2-methyl-4-(methylsulfonyl)benzoic acid Not in list C12H13NO5S CS(=O)(=O)c2ccc(c(C)c2C=1CCON=1)C(O)=O InChI=1/C12H13NO5S/c1-7-8(12(14)15)3-4-10(19(2,16)17)11(7)9-5-6-18-13-9/h3-4H,5-6H2,1-2H3,(H,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: France Topramezone (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone 03Feb2014 2014 doi:10.2903/j.efsa.2014.3540
+Topramezone 606-699-4 210631-68-8 single chemical entity Component is a metabolite of the substance 3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-(methylsulfonyl)benzoic acid 3-(4,5-dihydroisoxazol-3-yl)-2-methyl-4-(methylsulfonyl)benzoic acid Not in list C12H13NO5S CS(=O)(=O)c2ccc(c(C)c2C=1CCON=1)C(O)=O InChI=1/C12H13NO5S/c1-7-8(12(14)15)3-4-10(19(2,16)17)11(7)9-5-6-18-13-9/h3-4H,5-6H2,1-2H3,(H,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: France Topramezone (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone 03Feb2014 2014 doi:10.2903/j.efsa.2014.3540
+Topramezone 606-699-4 210631-68-8 single chemical entity Component is a metabolite of the substance 3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-(methylsulfonyl)benzoic acid 3-(4,5-dihydroisoxazol-3-yl)-2-methyl-4-(methylsulfonyl)benzoic acid Not in list C12H13NO5S CS(=O)(=O)c2ccc(c(C)c2C=1CCON=1)C(O)=O InChI=1/C12H13NO5S/c1-7-8(12(14)15)3-4-10(19(2,16)17)11(7)9-5-6-18-13-9/h3-4H,5-6H2,1-2H3,(H,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: France Topramezone (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone 03Feb2014 2014 doi:10.2903/j.efsa.2014.3540
+Topramezone 606-699-4 210631-68-8 single chemical entity Component is a metabolite of the substance 3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-(methylsulfonyl)benzoic acid 3-(4,5-dihydroisoxazol-3-yl)-2-methyl-4-(methylsulfonyl)benzoic acid Not in list C12H13NO5S CS(=O)(=O)c2ccc(c(C)c2C=1CCON=1)C(O)=O InChI=1/C12H13NO5S/c1-7-8(12(14)15)3-4-10(19(2,16)17)11(7)9-5-6-18-13-9/h3-4H,5-6H2,1-2H3,(H,14,15) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI Male intraperitoneal 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: France Topramezone (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone 03Feb2014 2014 doi:10.2903/j.efsa.2014.3540
+Topramezone 606-699-4 210631-68-8 single chemical entity Component is a metabolite of the substance 3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-(methylsulfonyl)benzoic acid 3-(4,5-dihydroisoxazol-3-yl)-2-methyl-4-(methylsulfonyl)benzoic acid Not in list C12H13NO5S CS(=O)(=O)c2ccc(c(C)c2C=1CCON=1)C(O)=O InChI=1/C12H13NO5S/c1-7-8(12(14)15)3-4-10(19(2,16)17)11(7)9-5-6-18-13-9/h3-4H,5-6H2,1-2H3,(H,14,15) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI Male intraperitoneal 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: France Topramezone (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone 03Feb2014 2014 doi:10.2903/j.efsa.2014.3540
+Triazoxide 276-668-4 72459-58-6 single chemical entity Component is identical to the substance Triazoxide 276-668-4 72459-58-6 7-chloro-3-(1H-imidazol-1-yl)-1,2,4-benzotriazine 1-oxide Triazoxide C10H6ClN5O Clc1ccc2nc(n[n+]([O-])c2c1)n3ccnc3 InChI=1S/C10H6ClN5O/c11-7-1-2-8-9(5-7)16(17)14-10(13-8)15-4-3-12-6-15/h1-6H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Triazoxide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triazoxide 01Mar2011 2011 doi:10.2903/j.efsa.2011.2018
+Triazoxide 276-668-4 72459-58-6 single chemical entity Component is identical to the substance Triazoxide 276-668-4 72459-58-6 7-chloro-3-(1H-imidazol-1-yl)-1,2,4-benzotriazine 1-oxide Triazoxide C10H6ClN5O Clc1ccc2nc(n[n+]([O-])c2c1)n3ccnc3 InChI=1S/C10H6ClN5O/c11-7-1-2-8-9(5-7)16(17)14-10(13-8)15-4-3-12-6-15/h1-6H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Triazoxide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triazoxide 01Mar2011 2011 doi:10.2903/j.efsa.2011.2018
+Triazoxide 276-668-4 72459-58-6 single chemical entity Component is identical to the substance Triazoxide 276-668-4 72459-58-6 7-chloro-3-(1H-imidazol-1-yl)-1,2,4-benzotriazine 1-oxide Triazoxide C10H6ClN5O Clc1ccc2nc(n[n+]([O-])c2c1)n3ccnc3 InChI=1S/C10H6ClN5O/c11-7-1-2-8-9(5-7)16(17)14-10(13-8)15-4-3-12-6-15/h1-6H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Triazoxide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triazoxide 01Mar2011 2011 doi:10.2903/j.efsa.2011.2018
+Triazoxide 276-668-4 72459-58-6 single chemical entity Component is identical to the substance Triazoxide 276-668-4 72459-58-6 7-chloro-3-(1H-imidazol-1-yl)-1,2,4-benzotriazine 1-oxide Triazoxide C10H6ClN5O Clc1ccc2nc(n[n+]([O-])c2c1)n3ccnc3 InChI=1S/C10H6ClN5O/c11-7-1-2-8-9(5-7)16(17)14-10(13-8)15-4-3-12-6-15/h1-6H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Triazoxide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triazoxide 01Mar2011 2011 doi:10.2903/j.efsa.2011.2018
+Triazoxide 276-668-4 72459-58-6 single chemical entity Component is identical to the substance Triazoxide 276-668-4 72459-58-6 7-chloro-3-(1H-imidazol-1-yl)-1,2,4-benzotriazine 1-oxide Triazoxide C10H6ClN5O Clc1ccc2nc(n[n+]([O-])c2c1)n3ccnc3 InChI=1S/C10H6ClN5O/c11-7-1-2-8-9(5-7)16(17)14-10(13-8)15-4-3-12-6-15/h1-6H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Triazoxide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triazoxide 01Mar2011 2011 doi:10.2903/j.efsa.2011.2018
+Triazoxide 276-668-4 72459-58-6 single chemical entity Component is identical to the substance Triazoxide 276-668-4 72459-58-6 7-chloro-3-(1H-imidazol-1-yl)-1,2,4-benzotriazine 1-oxide Triazoxide C10H6ClN5O Clc1ccc2nc(n[n+]([O-])c2c1)n3ccnc3 InChI=1S/C10H6ClN5O/c11-7-1-2-8-9(5-7)16(17)14-10(13-8)15-4-3-12-6-15/h1-6H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Triazoxide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triazoxide 01Mar2011 2011 doi:10.2903/j.efsa.2011.2018
+Triazoxide 276-668-4 72459-58-6 single chemical entity Component is identical to the substance Triazoxide 276-668-4 72459-58-6 7-chloro-3-(1H-imidazol-1-yl)-1,2,4-benzotriazine 1-oxide Triazoxide C10H6ClN5O Clc1ccc2nc(n[n+]([O-])c2c1)n3ccnc3 InChI=1S/C10H6ClN5O/c11-7-1-2-8-9(5-7)16(17)14-10(13-8)15-4-3-12-6-15/h1-6H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Triazoxide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triazoxide 01Mar2011 2011 doi:10.2903/j.efsa.2011.2018
+Triazoxide 276-668-4 72459-58-6 single chemical entity Component is identical to the substance Triazoxide 276-668-4 72459-58-6 7-chloro-3-(1H-imidazol-1-yl)-1,2,4-benzotriazine 1-oxide Triazoxide C10H6ClN5O Clc1ccc2nc(n[n+]([O-])c2c1)n3ccnc3 InChI=1S/C10H6ClN5O/c11-7-1-2-8-9(5-7)16(17)14-10(13-8)15-4-3-12-6-15/h1-6H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Triazoxide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triazoxide 01Mar2011 2011 doi:10.2903/j.efsa.2011.2018
+Triazoxide 276-668-4 72459-58-6 single chemical entity Component is identical to the substance Triazoxide 276-668-4 72459-58-6 7-chloro-3-(1H-imidazol-1-yl)-1,2,4-benzotriazine 1-oxide Triazoxide C10H6ClN5O Clc1ccc2nc(n[n+]([O-])c2c1)n3ccnc3 InChI=1S/C10H6ClN5O/c11-7-1-2-8-9(5-7)16(17)14-10(13-8)15-4-3-12-6-15/h1-6H organic compound Other Other gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) W3110 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Triazoxide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triazoxide 01Mar2011 2011 doi:10.2903/j.efsa.2011.2018
+Triazoxide 276-668-4 72459-58-6 single chemical entity Component is identical to the substance Triazoxide 276-668-4 72459-58-6 7-chloro-3-(1H-imidazol-1-yl)-1,2,4-benzotriazine 1-oxide Triazoxide C10H6ClN5O Clc1ccc2nc(n[n+]([O-])c2c1)n3ccnc3 InChI=1S/C10H6ClN5O/c11-7-1-2-8-9(5-7)16(17)14-10(13-8)15-4-3-12-6-15/h1-6H organic compound Other Other gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) W3110 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Triazoxide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triazoxide 01Mar2011 2011 doi:10.2903/j.efsa.2011.2018
+Triazoxide 276-668-4 72459-58-6 single chemical entity Component is identical to the substance Triazoxide 276-668-4 72459-58-6 7-chloro-3-(1H-imidazol-1-yl)-1,2,4-benzotriazine 1-oxide Triazoxide C10H6ClN5O Clc1ccc2nc(n[n+]([O-])c2c1)n3ccnc3 InChI=1S/C10H6ClN5O/c11-7-1-2-8-9(5-7)16(17)14-10(13-8)15-4-3-12-6-15/h1-6H organic compound Other Other gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) (k12)p3478 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Triazoxide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triazoxide 01Mar2011 2011 doi:10.2903/j.efsa.2011.2018
+Triazoxide 276-668-4 72459-58-6 single chemical entity Component is identical to the substance Triazoxide 276-668-4 72459-58-6 7-chloro-3-(1H-imidazol-1-yl)-1,2,4-benzotriazine 1-oxide Triazoxide C10H6ClN5O Clc1ccc2nc(n[n+]([O-])c2c1)n3ccnc3 InChI=1S/C10H6ClN5O/c11-7-1-2-8-9(5-7)16(17)14-10(13-8)15-4-3-12-6-15/h1-6H organic compound Other Other gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) (k12)p3478 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Triazoxide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triazoxide 01Mar2011 2011 doi:10.2903/j.efsa.2011.2018
+Triazoxide 276-668-4 72459-58-6 single chemical entity Component is identical to the substance Triazoxide 276-668-4 72459-58-6 7-chloro-3-(1H-imidazol-1-yl)-1,2,4-benzotriazine 1-oxide Triazoxide C10H6ClN5O Clc1ccc2nc(n[n+]([O-])c2c1)n3ccnc3 InChI=1S/C10H6ClN5O/c11-7-1-2-8-9(5-7)16(17)14-10(13-8)15-4-3-12-6-15/h1-6H organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Triazoxide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triazoxide 01Mar2011 2011 doi:10.2903/j.efsa.2011.2018
+Triazoxide 276-668-4 72459-58-6 single chemical entity Component is identical to the substance Triazoxide 276-668-4 72459-58-6 7-chloro-3-(1H-imidazol-1-yl)-1,2,4-benzotriazine 1-oxide Triazoxide C10H6ClN5O Clc1ccc2nc(n[n+]([O-])c2c1)n3ccnc3 InChI=1S/C10H6ClN5O/c11-7-1-2-8-9(5-7)16(17)14-10(13-8)15-4-3-12-6-15/h1-6H organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Triazoxide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triazoxide 01Mar2011 2011 doi:10.2903/j.efsa.2011.2018
+Triazoxide 276-668-4 72459-58-6 single chemical entity Component is identical to the substance Triazoxide 276-668-4 72459-58-6 7-chloro-3-(1H-imidazol-1-yl)-1,2,4-benzotriazine 1-oxide Triazoxide C10H6ClN5O Clc1ccc2nc(n[n+]([O-])c2c1)n3ccnc3 InChI=1S/C10H6ClN5O/c11-7-1-2-8-9(5-7)16(17)14-10(13-8)15-4-3-12-6-15/h1-6H organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Triazoxide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triazoxide 01Mar2011 2011 doi:10.2903/j.efsa.2011.2018
+Triazoxide 276-668-4 72459-58-6 single chemical entity Component is identical to the substance Triazoxide 276-668-4 72459-58-6 7-chloro-3-(1H-imidazol-1-yl)-1,2,4-benzotriazine 1-oxide Triazoxide C10H6ClN5O Clc1ccc2nc(n[n+]([O-])c2c1)n3ccnc3 InChI=1S/C10H6ClN5O/c11-7-1-2-8-9(5-7)16(17)14-10(13-8)15-4-3-12-6-15/h1-6H organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Positive RMS: The United Kingdom Triazoxide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triazoxide 01Mar2011 2011 doi:10.2903/j.efsa.2011.2018
+Triazoxide 276-668-4 72459-58-6 single chemical entity Component is identical to the substance Triazoxide 276-668-4 72459-58-6 7-chloro-3-(1H-imidazol-1-yl)-1,2,4-benzotriazine 1-oxide Triazoxide C10H6ClN5O Clc1ccc2nc(n[n+]([O-])c2c1)n3ccnc3 InChI=1S/C10H6ClN5O/c11-7-1-2-8-9(5-7)16(17)14-10(13-8)15-4-3-12-6-15/h1-6H organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Triazoxide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triazoxide 01Mar2011 2011 doi:10.2903/j.efsa.2011.2018
+Triazoxide 276-668-4 72459-58-6 single chemical entity Component is identical to the substance Triazoxide 276-668-4 72459-58-6 7-chloro-3-(1H-imidazol-1-yl)-1,2,4-benzotriazine 1-oxide Triazoxide C10H6ClN5O Clc1ccc2nc(n[n+]([O-])c2c1)n3ccnc3 InChI=1S/C10H6ClN5O/c11-7-1-2-8-9(5-7)16(17)14-10(13-8)15-4-3-12-6-15/h1-6H organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 10 Male/Female Not reported 6.0000000000 h yes not applicable Inconclusive direct evidence-cytotoxicity RMS: The United Kingdom Triazoxide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triazoxide 01Mar2011 2011 doi:10.2903/j.efsa.2011.2018
+Triazoxide 276-668-4 72459-58-6 single chemical entity Component is identical to the substance Triazoxide 276-668-4 72459-58-6 7-chloro-3-(1H-imidazol-1-yl)-1,2,4-benzotriazine 1-oxide Triazoxide C10H6ClN5O Clc1ccc2nc(n[n+]([O-])c2c1)n3ccnc3 InChI=1S/C10H6ClN5O/c11-7-1-2-8-9(5-7)16(17)14-10(13-8)15-4-3-12-6-15/h1-6H organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Hamster (as animal) Chinese 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Triazoxide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triazoxide 01Mar2011 2011 doi:10.2903/j.efsa.2011.2018
+Triazoxide 276-668-4 72459-58-6 single chemical entity Component is identical to the substance Triazoxide 276-668-4 72459-58-6 7-chloro-3-(1H-imidazol-1-yl)-1,2,4-benzotriazine 1-oxide Triazoxide C10H6ClN5O Clc1ccc2nc(n[n+]([O-])c2c1)n3ccnc3 InChI=1S/C10H6ClN5O/c11-7-1-2-8-9(5-7)16(17)14-10(13-8)15-4-3-12-6-15/h1-6H organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Hamster (as animal) Chinese 10 Male/Female oral: gavage 6.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Triazoxide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triazoxide 01Mar2011 2011 doi:10.2903/j.efsa.2011.2018
+Triazoxide 276-668-4 72459-58-6 single chemical entity Component is identical to the substance Triazoxide 276-668-4 72459-58-6 7-chloro-3-(1H-imidazol-1-yl)-1,2,4-benzotriazine 1-oxide Triazoxide C10H6ClN5O Clc1ccc2nc(n[n+]([O-])c2c1)n3ccnc3 InChI=1S/C10H6ClN5O/c11-7-1-2-8-9(5-7)16(17)14-10(13-8)15-4-3-12-6-15/h1-6H organic compound Other Other chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) Yes Acceptable House mouse (as animal) NMRI 50 Male oral: gavage 48.0000000000 D yes not applicable Negative RMS: The United Kingdom Triazoxide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triazoxide 01Mar2011 2011 doi:10.2903/j.efsa.2011.2018
+Triazoxide 276-668-4 72459-58-6 single chemical entity Component is identical to the substance Triazoxide 276-668-4 72459-58-6 7-chloro-3-(1H-imidazol-1-yl)-1,2,4-benzotriazine 1-oxide Triazoxide C10H6ClN5O Clc1ccc2nc(n[n+]([O-])c2c1)n3ccnc3 InChI=1S/C10H6ClN5O/c11-7-1-2-8-9(5-7)16(17)14-10(13-8)15-4-3-12-6-15/h1-6H organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) NMRI 10 Male/Female intraperitoneal 42.0000000000 h yes not applicable Negative RMS: The United Kingdom Triazoxide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triazoxide 01Mar2011 2011 doi:10.2903/j.efsa.2011.2018
+Triazoxide 276-668-4 72459-58-6 single chemical entity Component is identical to the substance Triazoxide 276-668-4 72459-58-6 7-chloro-3-(1H-imidazol-1-yl)-1,2,4-benzotriazine 1-oxide Triazoxide C10H6ClN5O Clc1ccc2nc(n[n+]([O-])c2c1)n3ccnc3 InChI=1S/C10H6ClN5O/c11-7-1-2-8-9(5-7)16(17)14-10(13-8)15-4-3-12-6-15/h1-6H organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) NMRI 10 Male/Female intraperitoneal 18.0000000000 h yes not applicable Negative RMS: The United Kingdom Triazoxide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triazoxide 01Mar2011 2011 doi:10.2903/j.efsa.2011.2018
+Triazoxide 276-668-4 72459-58-6 single chemical entity Component is identical to the substance Triazoxide 276-668-4 72459-58-6 7-chloro-3-(1H-imidazol-1-yl)-1,2,4-benzotriazine 1-oxide Triazoxide C10H6ClN5O Clc1ccc2nc(n[n+]([O-])c2c1)n3ccnc3 InChI=1S/C10H6ClN5O/c11-7-1-2-8-9(5-7)16(17)14-10(13-8)15-4-3-12-6-15/h1-6H organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) NMRI 10 Male/Female intraperitoneal 6.0000000000 h yes not applicable Negative RMS: The United Kingdom Triazoxide 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triazoxide 01Mar2011 2011 doi:10.2903/j.efsa.2011.2018
+Tribenuron-methyl 101200-48-0 single chemical entity Component is identical to the substance Tribenuron-methyl 101200-48-0 methyl2-[[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-methylcarbamoyl]sulfamoyl]benzoate Tribenuron-methyl C15-H17-N5-O6-S CC1=NC(=NC(=N1)OC)N(C)C(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C15H17N5O6S/c1-9-16-13(18-14(17-9)26-4)20(2)15(22)19-27(23,24)11-8-6-5-7-10(11)12(21)25-3/h5-8H,1-4H3,(H,19,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Sweden Tribenuron-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tribenuron 31Mar2005 2005 doi:10.2903/j.efsa.2005.15r
+Tribenuron-methyl 101200-48-0 single chemical entity Component is identical to the substance Tribenuron-methyl 101200-48-0 methyl2-[[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-methylcarbamoyl]sulfamoyl]benzoate Tribenuron-methyl C15-H17-N5-O6-S CC1=NC(=NC(=N1)OC)N(C)C(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C15H17N5O6S/c1-9-16-13(18-14(17-9)26-4)20(2)15(22)19-27(23,24)11-8-6-5-7-10(11)12(21)25-3/h5-8H,1-4H3,(H,19,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Sweden Tribenuron-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tribenuron 31Mar2005 2005 doi:10.2903/j.efsa.2005.15r
+Tribenuron-methyl 101200-48-0 single chemical entity Component is identical to the substance Tribenuron-methyl 101200-48-0 methyl2-[[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-methylcarbamoyl]sulfamoyl]benzoate Tribenuron-methyl C15-H17-N5-O6-S CC1=NC(=NC(=N1)OC)N(C)C(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C15H17N5O6S/c1-9-16-13(18-14(17-9)26-4)20(2)15(22)19-27(23,24)11-8-6-5-7-10(11)12(21)25-3/h5-8H,1-4H3,(H,19,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Sweden Tribenuron-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tribenuron 31Mar2005 2005 doi:10.2903/j.efsa.2005.15r
+Tribenuron-methyl 101200-48-0 single chemical entity Component is identical to the substance Tribenuron-methyl 101200-48-0 methyl2-[[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-methylcarbamoyl]sulfamoyl]benzoate Tribenuron-methyl C15-H17-N5-O6-S CC1=NC(=NC(=N1)OC)N(C)C(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C15H17N5O6S/c1-9-16-13(18-14(17-9)26-4)20(2)15(22)19-27(23,24)11-8-6-5-7-10(11)12(21)25-3/h5-8H,1-4H3,(H,19,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Sweden Tribenuron-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tribenuron 31Mar2005 2005 doi:10.2903/j.efsa.2005.15r
+Tribenuron-methyl 101200-48-0 single chemical entity Component is identical to the substance Tribenuron-methyl 101200-48-0 methyl2-[[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-methylcarbamoyl]sulfamoyl]benzoate Tribenuron-methyl C15-H17-N5-O6-S CC1=NC(=NC(=N1)OC)N(C)C(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C15H17N5O6S/c1-9-16-13(18-14(17-9)26-4)20(2)15(22)19-27(23,24)11-8-6-5-7-10(11)12(21)25-3/h5-8H,1-4H3,(H,19,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Sweden Tribenuron-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tribenuron 31Mar2005 2005 doi:10.2903/j.efsa.2005.15r
+Tribenuron-methyl 101200-48-0 single chemical entity Component is identical to the substance Tribenuron-methyl 101200-48-0 methyl2-[[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-methylcarbamoyl]sulfamoyl]benzoate Tribenuron-methyl C15-H17-N5-O6-S CC1=NC(=NC(=N1)OC)N(C)C(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C15H17N5O6S/c1-9-16-13(18-14(17-9)26-4)20(2)15(22)19-27(23,24)11-8-6-5-7-10(11)12(21)25-3/h5-8H,1-4H3,(H,19,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Sweden Tribenuron-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tribenuron 31Mar2005 2005 doi:10.2903/j.efsa.2005.15r
+Tribenuron-methyl 101200-48-0 single chemical entity Component is identical to the substance Tribenuron-methyl 101200-48-0 methyl2-[[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-methylcarbamoyl]sulfamoyl]benzoate Tribenuron-methyl C15-H17-N5-O6-S CC1=NC(=NC(=N1)OC)N(C)C(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C15H17N5O6S/c1-9-16-13(18-14(17-9)26-4)20(2)15(22)19-27(23,24)11-8-6-5-7-10(11)12(21)25-3/h5-8H,1-4H3,(H,19,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle without Negative RMS: Sweden Tribenuron-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tribenuron 31Mar2005 2005 doi:10.2903/j.efsa.2005.15r
+Tribenuron-methyl 101200-48-0 single chemical entity Component is identical to the substance Tribenuron-methyl 101200-48-0 methyl2-[[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-methylcarbamoyl]sulfamoyl]benzoate Tribenuron-methyl C15-H17-N5-O6-S CC1=NC(=NC(=N1)OC)N(C)C(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C15H17N5O6S/c1-9-16-13(18-14(17-9)26-4)20(2)15(22)19-27(23,24)11-8-6-5-7-10(11)12(21)25-3/h5-8H,1-4H3,(H,19,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle with Negative RMS: Sweden Tribenuron-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tribenuron 31Mar2005 2005 doi:10.2903/j.efsa.2005.15r
+Tribenuron-methyl 101200-48-0 single chemical entity Component is identical to the substance Tribenuron-methyl 101200-48-0 methyl2-[[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-methylcarbamoyl]sulfamoyl]benzoate Tribenuron-methyl C15-H17-N5-O6-S CC1=NC(=NC(=N1)OC)N(C)C(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C15H17N5O6S/c1-9-16-13(18-14(17-9)26-4)20(2)15(22)19-27(23,24)11-8-6-5-7-10(11)12(21)25-3/h5-8H,1-4H3,(H,19,22) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) hepatocytes Not reported yes, concurrent no treatment with Negative RMS: Sweden Tribenuron-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tribenuron 31Mar2005 2005 doi:10.2903/j.efsa.2005.15r
+Tribenuron-methyl 101200-48-0 single chemical entity Component is identical to the substance Tribenuron-methyl 101200-48-0 methyl2-[[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-methylcarbamoyl]sulfamoyl]benzoate Tribenuron-methyl C15-H17-N5-O6-S CC1=NC(=NC(=N1)OC)N(C)C(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C15H17N5O6S/c1-9-16-13(18-14(17-9)26-4)20(2)15(22)19-27(23,24)11-8-6-5-7-10(11)12(21)25-3/h5-8H,1-4H3,(H,19,22) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) hepatocytes Not reported yes, concurrent no treatment without Negative RMS: Sweden Tribenuron-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tribenuron 31Mar2005 2005 doi:10.2903/j.efsa.2005.15r
+Tribenuron-methyl 101200-48-0 single chemical entity Component is identical to the substance Tribenuron-methyl 101200-48-0 methyl2-[[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-methylcarbamoyl]sulfamoyl]benzoate Tribenuron-methyl C15-H17-N5-O6-S CC1=NC(=NC(=N1)OC)N(C)C(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C15H17N5O6S/c1-9-16-13(18-14(17-9)26-4)20(2)15(22)19-27(23,24)11-8-6-5-7-10(11)12(21)25-3/h5-8H,1-4H3,(H,19,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Sweden Tribenuron-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tribenuron 31Mar2005 2005 doi:10.2903/j.efsa.2005.15r
+Tribenuron-methyl 101200-48-0 single chemical entity Component is identical to the substance Tribenuron-methyl 101200-48-0 methyl2-[[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-methylcarbamoyl]sulfamoyl]benzoate Tribenuron-methyl C15-H17-N5-O6-S CC1=NC(=NC(=N1)OC)N(C)C(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C15H17N5O6S/c1-9-16-13(18-14(17-9)26-4)20(2)15(22)19-27(23,24)11-8-6-5-7-10(11)12(21)25-3/h5-8H,1-4H3,(H,19,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Sweden Tribenuron-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tribenuron 31Mar2005 2005 doi:10.2903/j.efsa.2005.15r
+Tribenuron-methyl 101200-48-0 single chemical entity Component is identical to the substance Tribenuron-methyl 101200-48-0 methyl2-[[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-methylcarbamoyl]sulfamoyl]benzoate Tribenuron-methyl C15-H17-N5-O6-S CC1=NC(=NC(=N1)OC)N(C)C(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C15H17N5O6S/c1-9-16-13(18-14(17-9)26-4)20(2)15(22)19-27(23,24)11-8-6-5-7-10(11)12(21)25-3/h5-8H,1-4H3,(H,19,22) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Rat (as animal) hepatocytes Not reported no data without Negative RMS: Sweden Tribenuron-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tribenuron 31Mar2005 2005 doi:10.2903/j.efsa.2005.15r
+Tribenuron-methyl 101200-48-0 single chemical entity Component is identical to the substance Tribenuron-methyl 101200-48-0 methyl2-[[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-methylcarbamoyl]sulfamoyl]benzoate Tribenuron-methyl C15-H17-N5-O6-S CC1=NC(=NC(=N1)OC)N(C)C(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C15H17N5O6S/c1-9-16-13(18-14(17-9)26-4)20(2)15(22)19-27(23,24)11-8-6-5-7-10(11)12(21)25-3/h5-8H,1-4H3,(H,19,22) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Sprague-Dawley 10 Male/Female oral: unspecified 6.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Sweden Tribenuron-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tribenuron 31Mar2005 2005 doi:10.2903/j.efsa.2005.15r
+Tribenuron-methyl 101200-48-0 single chemical entity Component is identical to the substance Tribenuron-methyl 101200-48-0 methyl2-[[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-methylcarbamoyl]sulfamoyl]benzoate Tribenuron-methyl C15-H17-N5-O6-S CC1=NC(=NC(=N1)OC)N(C)C(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C15H17N5O6S/c1-9-16-13(18-14(17-9)26-4)20(2)15(22)19-27(23,24)11-8-6-5-7-10(11)12(21)25-3/h5-8H,1-4H3,(H,19,22) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Sprague-Dawley 10 Male/Female oral: unspecified 48.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Sweden Tribenuron-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tribenuron 31Mar2005 2005 doi:10.2903/j.efsa.2005.15r
+Tribenuron-methyl 101200-48-0 single chemical entity Component is identical to the substance Tribenuron-methyl 101200-48-0 methyl2-[[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-methylcarbamoyl]sulfamoyl]benzoate Tribenuron-methyl C15-H17-N5-O6-S CC1=NC(=NC(=N1)OC)N(C)C(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C15H17N5O6S/c1-9-16-13(18-14(17-9)26-4)20(2)15(22)19-27(23,24)11-8-6-5-7-10(11)12(21)25-3/h5-8H,1-4H3,(H,19,22) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Sprague-Dawley 10 Male/Female oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Sweden Tribenuron-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tribenuron 31Mar2005 2005 doi:10.2903/j.efsa.2005.15r
+Tribenuron-methyl 101200-48-0 single chemical entity Component is identical to the substance Tribenuron-methyl 101200-48-0 methyl2-[[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-methylcarbamoyl]sulfamoyl]benzoate Tribenuron-methyl C15-H17-N5-O6-S CC1=NC(=NC(=N1)OC)N(C)C(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C15H17N5O6S/c1-9-16-13(18-14(17-9)26-4)20(2)15(22)19-27(23,24)11-8-6-5-7-10(11)12(21)25-3/h5-8H,1-4H3,(H,19,22) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 6 Male/Female Not reported 72.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Sweden Tribenuron-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tribenuron 31Mar2005 2005 doi:10.2903/j.efsa.2005.15r
+Tribenuron-methyl 101200-48-0 single chemical entity Component is identical to the substance Tribenuron-methyl 101200-48-0 methyl2-[[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-methylcarbamoyl]sulfamoyl]benzoate Tribenuron-methyl C15-H17-N5-O6-S CC1=NC(=NC(=N1)OC)N(C)C(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C15H17N5O6S/c1-9-16-13(18-14(17-9)26-4)20(2)15(22)19-27(23,24)11-8-6-5-7-10(11)12(21)25-3/h5-8H,1-4H3,(H,19,22) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 6 Male/Female Not reported 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Sweden Tribenuron-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tribenuron 31Mar2005 2005 doi:10.2903/j.efsa.2005.15r
+Tribenuron-methyl 101200-48-0 single chemical entity Component is identical to the substance Tribenuron-methyl 101200-48-0 methyl2-[[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-methylcarbamoyl]sulfamoyl]benzoate Tribenuron-methyl C15-H17-N5-O6-S CC1=NC(=NC(=N1)OC)N(C)C(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC InChI=1S/C15H17N5O6S/c1-9-16-13(18-14(17-9)26-4)20(2)15(22)19-27(23,24)11-8-6-5-7-10(11)12(21)25-3/h5-8H,1-4H3,(H,19,22) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 6 Male/Female Not reported 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Sweden Tribenuron-methyl 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tribenuron 31Mar2005 2005 doi:10.2903/j.efsa.2005.15r
+Trichlorfon 200-149-3 52-68-6 single chemical entity Component is identical to the substance Trichlorfon 200-149-3 52-68-6 2,2,2-Trichloro-1-dimethoxyphosphorylethanol Trichlorfon C4H8Cl3O4P COP(=O)(C(C(Cl)(Cl)Cl)O)OC InChI=1S/C4H8Cl3O4P/c1-10-12(9,11-2)3(8)4(5,6)7/h3,8H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Spain Trichlorfon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trichlorfon 15Jun2006 2006 doi:10.2903/j.efsa.2006.76r
+Trichlorfon 200-149-3 52-68-6 single chemical entity Component is identical to the substance Trichlorfon 200-149-3 52-68-6 2,2,2-Trichloro-1-dimethoxyphosphorylethanol Trichlorfon C4H8Cl3O4P COP(=O)(C(C(Cl)(Cl)Cl)O)OC InChI=1S/C4H8Cl3O4P/c1-10-12(9,11-2)3(8)4(5,6)7/h3,8H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Spain Trichlorfon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trichlorfon 15Jun2006 2006 doi:10.2903/j.efsa.2006.76r
+Trichlorfon 200-149-3 52-68-6 single chemical entity Component is identical to the substance Trichlorfon 200-149-3 52-68-6 2,2,2-Trichloro-1-dimethoxyphosphorylethanol Trichlorfon C4H8Cl3O4P COP(=O)(C(C(Cl)(Cl)Cl)O)OC InChI=1S/C4H8Cl3O4P/c1-10-12(9,11-2)3(8)4(5,6)7/h3,8H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes without Negative RMS: Spain Trichlorfon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trichlorfon 15Jun2006 2006 doi:10.2903/j.efsa.2006.76r
+Trichlorfon 200-149-3 52-68-6 single chemical entity Component is identical to the substance Trichlorfon 200-149-3 52-68-6 2,2,2-Trichloro-1-dimethoxyphosphorylethanol Trichlorfon C4H8Cl3O4P COP(=O)(C(C(Cl)(Cl)Cl)O)OC InChI=1S/C4H8Cl3O4P/c1-10-12(9,11-2)3(8)4(5,6)7/h3,8H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Spain Trichlorfon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trichlorfon 15Jun2006 2006 doi:10.2903/j.efsa.2006.76r
+Trichlorfon 200-149-3 52-68-6 single chemical entity Component is identical to the substance Trichlorfon 200-149-3 52-68-6 2,2,2-Trichloro-1-dimethoxyphosphorylethanol Trichlorfon C4H8Cl3O4P COP(=O)(C(C(Cl)(Cl)Cl)O)OC InChI=1S/C4H8Cl3O4P/c1-10-12(9,11-2)3(8)4(5,6)7/h3,8H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Spain Trichlorfon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trichlorfon 15Jun2006 2006 doi:10.2903/j.efsa.2006.76r
+Trichlorfon 200-149-3 52-68-6 single chemical entity Component is identical to the substance Trichlorfon 200-149-3 52-68-6 2,2,2-Trichloro-1-dimethoxyphosphorylethanol Trichlorfon C4H8Cl3O4P COP(=O)(C(C(Cl)(Cl)Cl)O)OC InChI=1S/C4H8Cl3O4P/c1-10-12(9,11-2)3(8)4(5,6)7/h3,8H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Spain Trichlorfon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trichlorfon 15Jun2006 2006 doi:10.2903/j.efsa.2006.76r
+Trichlorfon 200-149-3 52-68-6 single chemical entity Component is identical to the substance Trichlorfon 200-149-3 52-68-6 2,2,2-Trichloro-1-dimethoxyphosphorylethanol Trichlorfon C4H8Cl3O4P COP(=O)(C(C(Cl)(Cl)Cl)O)OC InChI=1S/C4H8Cl3O4P/c1-10-12(9,11-2)3(8)4(5,6)7/h3,8H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Spain Trichlorfon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trichlorfon 15Jun2006 2006 doi:10.2903/j.efsa.2006.76r
+Trichlorfon 200-149-3 52-68-6 single chemical entity Component is identical to the substance Trichlorfon 200-149-3 52-68-6 2,2,2-Trichloro-1-dimethoxyphosphorylethanol Trichlorfon C4H8Cl3O4P COP(=O)(C(C(Cl)(Cl)Cl)O)OC InChI=1S/C4H8Cl3O4P/c1-10-12(9,11-2)3(8)4(5,6)7/h3,8H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Spain Trichlorfon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trichlorfon 15Jun2006 2006 doi:10.2903/j.efsa.2006.76r
+Trichlorfon 200-149-3 52-68-6 single chemical entity Component is identical to the substance Trichlorfon 200-149-3 52-68-6 2,2,2-Trichloro-1-dimethoxyphosphorylethanol Trichlorfon C4H8Cl3O4P COP(=O)(C(C(Cl)(Cl)Cl)O)OC InChI=1S/C4H8Cl3O4P/c1-10-12(9,11-2)3(8)4(5,6)7/h3,8H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Spain Trichlorfon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trichlorfon 15Jun2006 2006 doi:10.2903/j.efsa.2006.76r
+Trichlorfon 200-149-3 52-68-6 single chemical entity Component is identical to the substance Trichlorfon 200-149-3 52-68-6 2,2,2-Trichloro-1-dimethoxyphosphorylethanol Trichlorfon C4H8Cl3O4P COP(=O)(C(C(Cl)(Cl)Cl)O)OC InChI=1S/C4H8Cl3O4P/c1-10-12(9,11-2)3(8)4(5,6)7/h3,8H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes with Negative RMS: Spain Trichlorfon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trichlorfon 15Jun2006 2006 doi:10.2903/j.efsa.2006.76r
+Trichlorfon 200-149-3 52-68-6 single chemical entity Component is identical to the substance Trichlorfon 200-149-3 52-68-6 2,2,2-Trichloro-1-dimethoxyphosphorylethanol Trichlorfon C4H8Cl3O4P COP(=O)(C(C(Cl)(Cl)Cl)O)OC InChI=1S/C4H8Cl3O4P/c1-10-12(9,11-2)3(8)4(5,6)7/h3,8H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Inconclusive RMS: Spain Trichlorfon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trichlorfon 15Jun2006 2006 doi:10.2903/j.efsa.2006.76r
+Trichlorfon 200-149-3 52-68-6 single chemical entity Component is identical to the substance Trichlorfon 200-149-3 52-68-6 2,2,2-Trichloro-1-dimethoxyphosphorylethanol Trichlorfon C4H8Cl3O4P COP(=O)(C(C(Cl)(Cl)Cl)O)OC InChI=1S/C4H8Cl3O4P/c1-10-12(9,11-2)3(8)4(5,6)7/h3,8H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Inconclusive RMS: Spain Trichlorfon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trichlorfon 15Jun2006 2006 doi:10.2903/j.efsa.2006.76r
+Trichlorfon 200-149-3 52-68-6 single chemical entity Component is identical to the substance Trichlorfon 200-149-3 52-68-6 2,2,2-Trichloro-1-dimethoxyphosphorylethanol Trichlorfon C4H8Cl3O4P COP(=O)(C(C(Cl)(Cl)Cl)O)OC InChI=1S/C4H8Cl3O4P/c1-10-12(9,11-2)3(8)4(5,6)7/h3,8H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Positive RMS: Spain Trichlorfon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trichlorfon 15Jun2006 2006 doi:10.2903/j.efsa.2006.76r
+Trichlorfon 200-149-3 52-68-6 single chemical entity Component is identical to the substance Trichlorfon 200-149-3 52-68-6 2,2,2-Trichloro-1-dimethoxyphosphorylethanol Trichlorfon C4H8Cl3O4P COP(=O)(C(C(Cl)(Cl)Cl)O)OC InChI=1S/C4H8Cl3O4P/c1-10-12(9,11-2)3(8)4(5,6)7/h3,8H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Positive RMS: Spain Trichlorfon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trichlorfon 15Jun2006 2006 doi:10.2903/j.efsa.2006.76r
+Trichlorfon 200-149-3 52-68-6 single chemical entity Component is identical to the substance Trichlorfon 200-149-3 52-68-6 2,2,2-Trichloro-1-dimethoxyphosphorylethanol Trichlorfon C4H8Cl3O4P COP(=O)(C(C(Cl)(Cl)Cl)O)OC InChI=1S/C4H8Cl3O4P/c1-10-12(9,11-2)3(8)4(5,6)7/h3,8H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Positive RMS: Spain Trichlorfon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trichlorfon 15Jun2006 2006 doi:10.2903/j.efsa.2006.76r
+Trichlorfon 200-149-3 52-68-6 single chemical entity Component is identical to the substance Trichlorfon 200-149-3 52-68-6 2,2,2-Trichloro-1-dimethoxyphosphorylethanol Trichlorfon C4H8Cl3O4P COP(=O)(C(C(Cl)(Cl)Cl)O)OC InChI=1S/C4H8Cl3O4P/c1-10-12(9,11-2)3(8)4(5,6)7/h3,8H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Positive RMS: Spain Trichlorfon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trichlorfon 15Jun2006 2006 doi:10.2903/j.efsa.2006.76r
+Trichlorfon 200-149-3 52-68-6 single chemical entity Component is identical to the substance Trichlorfon 200-149-3 52-68-6 2,2,2-Trichloro-1-dimethoxyphosphorylethanol Trichlorfon C4H8Cl3O4P COP(=O)(C(C(Cl)(Cl)Cl)O)OC InChI=1S/C4H8Cl3O4P/c1-10-12(9,11-2)3(8)4(5,6)7/h3,8H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) (k12)p3478 Not reported yes, concurrent vehicle with Negative RMS: Spain Trichlorfon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trichlorfon 15Jun2006 2006 doi:10.2903/j.efsa.2006.76r
+Trichlorfon 200-149-3 52-68-6 single chemical entity Component is identical to the substance Trichlorfon 200-149-3 52-68-6 2,2,2-Trichloro-1-dimethoxyphosphorylethanol Trichlorfon C4H8Cl3O4P COP(=O)(C(C(Cl)(Cl)Cl)O)OC InChI=1S/C4H8Cl3O4P/c1-10-12(9,11-2)3(8)4(5,6)7/h3,8H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) W3110 Not reported yes, concurrent vehicle with Negative RMS: Spain Trichlorfon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trichlorfon 15Jun2006 2006 doi:10.2903/j.efsa.2006.76r
+Trichlorfon 200-149-3 52-68-6 single chemical entity Component is identical to the substance Trichlorfon 200-149-3 52-68-6 2,2,2-Trichloro-1-dimethoxyphosphorylethanol Trichlorfon C4H8Cl3O4P COP(=O)(C(C(Cl)(Cl)Cl)O)OC InChI=1S/C4H8Cl3O4P/c1-10-12(9,11-2)3(8)4(5,6)7/h3,8H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) W3110 Not reported yes, concurrent vehicle without Negative RMS: Spain Trichlorfon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trichlorfon 15Jun2006 2006 doi:10.2903/j.efsa.2006.76r
+Trichlorfon 200-149-3 52-68-6 single chemical entity Component is identical to the substance Trichlorfon 200-149-3 52-68-6 2,2,2-Trichloro-1-dimethoxyphosphorylethanol Trichlorfon C4H8Cl3O4P COP(=O)(C(C(Cl)(Cl)Cl)O)OC InChI=1S/C4H8Cl3O4P/c1-10-12(9,11-2)3(8)4(5,6)7/h3,8H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) (k12)p3478 Not reported yes, concurrent vehicle without Negative RMS: Spain Trichlorfon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trichlorfon 15Jun2006 2006 doi:10.2903/j.efsa.2006.76r
+Trichlorfon 200-149-3 52-68-6 single chemical entity Component is identical to the substance Trichlorfon 200-149-3 52-68-6 2,2,2-Trichloro-1-dimethoxyphosphorylethanol Trichlorfon C4H8Cl3O4P COP(=O)(C(C(Cl)(Cl)Cl)O)OC InChI=1S/C4H8Cl3O4P/c1-10-12(9,11-2)3(8)4(5,6)7/h3,8H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 6.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Spain Trichlorfon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trichlorfon 15Jun2006 2006 doi:10.2903/j.efsa.2006.76r
+Trichlorfon 200-149-3 52-68-6 single chemical entity Component is identical to the substance Trichlorfon 200-149-3 52-68-6 2,2,2-Trichloro-1-dimethoxyphosphorylethanol Trichlorfon C4H8Cl3O4P COP(=O)(C(C(Cl)(Cl)Cl)O)OC InChI=1S/C4H8Cl3O4P/c1-10-12(9,11-2)3(8)4(5,6)7/h3,8H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) Yes Acceptable House mouse (as animal) NMRI 50 Male oral: gavage 48.0000000000 D yes not applicable Negative RMS: Spain Trichlorfon 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trichlorfon 15Jun2006 2006 doi:10.2903/j.efsa.2006.76r
+Triclopyr 259-597-3 55335-06-3 single chemical entity Component is identical to the substance Triclopyr 259-597-3 55335-06-3 [(3,5,6-trichloropyridin-2-yl)oxy]acetic acid Triclopyr C7H4Cl3NO3 O=C(O)COC1=C(Cl)C=C(Cl)C(Cl)=N1 InChI=1S/C7H4Cl3NO3/c8-3-1-4(9)7(11-6(3)10)14-2-5(12)13/h1H,2H2,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Ireland Triclopyr 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr 19Jan2006 2006 doi:10.2903/j.efsa.2006.56r
+Triclopyr 259-597-3 55335-06-3 single chemical entity Component is identical to the substance Triclopyr 259-597-3 55335-06-3 [(3,5,6-trichloropyridin-2-yl)oxy]acetic acid Triclopyr C7H4Cl3NO3 O=C(O)COC1=C(Cl)C=C(Cl)C(Cl)=N1 InChI=1S/C7H4Cl3NO3/c8-3-1-4(9)7(11-6(3)10)14-2-5(12)13/h1H,2H2,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Ireland Triclopyr 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr 19Jan2006 2006 doi:10.2903/j.efsa.2006.56r
+Triclopyr 259-597-3 55335-06-3 single chemical entity Component is identical to the substance Triclopyr 259-597-3 55335-06-3 [(3,5,6-trichloropyridin-2-yl)oxy]acetic acid Triclopyr C7H4Cl3NO3 O=C(O)COC1=C(Cl)C=C(Cl)C(Cl)=N1 InChI=1S/C7H4Cl3NO3/c8-3-1-4(9)7(11-6(3)10)14-2-5(12)13/h1H,2H2,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: Ireland Triclopyr 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr 19Jan2006 2006 doi:10.2903/j.efsa.2006.56r
+Triclopyr 259-597-3 55335-06-3 single chemical entity Component is identical to the substance Triclopyr 259-597-3 55335-06-3 [(3,5,6-trichloropyridin-2-yl)oxy]acetic acid Triclopyr C7H4Cl3NO3 O=C(O)COC1=C(Cl)C=C(Cl)C(Cl)=N1 InChI=1S/C7H4Cl3NO3/c8-3-1-4(9)7(11-6(3)10)14-2-5(12)13/h1H,2H2,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Ireland Triclopyr 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr 19Jan2006 2006 doi:10.2903/j.efsa.2006.56r
+Triclopyr 259-597-3 55335-06-3 single chemical entity Component is identical to the substance Triclopyr 259-597-3 55335-06-3 [(3,5,6-trichloropyridin-2-yl)oxy]acetic acid Triclopyr C7H4Cl3NO3 O=C(O)COC1=C(Cl)C=C(Cl)C(Cl)=N1 InChI=1S/C7H4Cl3NO3/c8-3-1-4(9)7(11-6(3)10)14-2-5(12)13/h1H,2H2,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Ireland Triclopyr 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr 19Jan2006 2006 doi:10.2903/j.efsa.2006.56r
+Triclopyr 259-597-3 55335-06-3 single chemical entity Component is identical to the substance Triclopyr 259-597-3 55335-06-3 [(3,5,6-trichloropyridin-2-yl)oxy]acetic acid Triclopyr C7H4Cl3NO3 O=C(O)COC1=C(Cl)C=C(Cl)C(Cl)=N1 InChI=1S/C7H4Cl3NO3/c8-3-1-4(9)7(11-6(3)10)14-2-5(12)13/h1H,2H2,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Ireland Triclopyr 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr 19Jan2006 2006 doi:10.2903/j.efsa.2006.56r
+Triclopyr 259-597-3 55335-06-3 single chemical entity Component is identical to the substance Triclopyr 259-597-3 55335-06-3 [(3,5,6-trichloropyridin-2-yl)oxy]acetic acid Triclopyr C7H4Cl3NO3 O=C(O)COC1=C(Cl)C=C(Cl)C(Cl)=N1 InChI=1S/C7H4Cl3NO3/c8-3-1-4(9)7(11-6(3)10)14-2-5(12)13/h1H,2H2,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Ireland Triclopyr 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr 19Jan2006 2006 doi:10.2903/j.efsa.2006.56r
+Triclopyr 259-597-3 55335-06-3 single chemical entity Component is identical to the substance Triclopyr 259-597-3 55335-06-3 [(3,5,6-trichloropyridin-2-yl)oxy]acetic acid Triclopyr C7H4Cl3NO3 O=C(O)COC1=C(Cl)C=C(Cl)C(Cl)=N1 InChI=1S/C7H4Cl3NO3/c8-3-1-4(9)7(11-6(3)10)14-2-5(12)13/h1H,2H2,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Ireland Triclopyr 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr 19Jan2006 2006 doi:10.2903/j.efsa.2006.56r
+Triclopyr 259-597-3 55335-06-3 single chemical entity Component is identical to the substance Triclopyr 259-597-3 55335-06-3 [(3,5,6-trichloropyridin-2-yl)oxy]acetic acid Triclopyr C7H4Cl3NO3 O=C(O)COC1=C(Cl)C=C(Cl)C(Cl)=N1 InChI=1S/C7H4Cl3NO3/c8-3-1-4(9)7(11-6(3)10)14-2-5(12)13/h1H,2H2,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: Ireland Triclopyr 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr 19Jan2006 2006 doi:10.2903/j.efsa.2006.56r
+Triclopyr 259-597-3 55335-06-3 single chemical entity Component is identical to the substance Triclopyr 259-597-3 55335-06-3 [(3,5,6-trichloropyridin-2-yl)oxy]acetic acid Triclopyr C7H4Cl3NO3 O=C(O)COC1=C(Cl)C=C(Cl)C(Cl)=N1 InChI=1S/C7H4Cl3NO3/c8-3-1-4(9)7(11-6(3)10)14-2-5(12)13/h1H,2H2,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Ireland Triclopyr 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr 19Jan2006 2006 doi:10.2903/j.efsa.2006.56r
+Triclopyr 259-597-3 55335-06-3 single chemical entity Component is part of a group assessment Triclopyr-butoxyethyl ester 265-024-8 64470-88-8 2-Butoxyethyl 2-(3,5,6-trichloropyridin-2-yl)oxyacetate Triclopyr-butoxyethyl ester C13H16Cl3NO4 CCCCOCCOC(=O)COC1=NC(=C(C=C1Cl)Cl)Cl InChI=1S/C13H16Cl3NO4/c1-2-3-4-19-5-6-20-11(18)8-21-13-10(15)7-9(14)12(16)17-13/h7H,2-6,8H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Ireland Triclopyr 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr 19Jan2006 2006 doi:10.2903/j.efsa.2006.56r
+Triclopyr 259-597-3 55335-06-3 single chemical entity Component is part of a group assessment Triclopyr-butoxyethyl ester 265-024-8 64470-88-8 2-Butoxyethyl 2-(3,5,6-trichloropyridin-2-yl)oxyacetate Triclopyr-butoxyethyl ester C13H16Cl3NO4 CCCCOCCOC(=O)COC1=NC(=C(C=C1Cl)Cl)Cl InChI=1S/C13H16Cl3NO4/c1-2-3-4-19-5-6-20-11(18)8-21-13-10(15)7-9(14)12(16)17-13/h7H,2-6,8H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Ireland Triclopyr 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr 19Jan2006 2006 doi:10.2903/j.efsa.2006.56r
+Triclopyr 259-597-3 55335-06-3 single chemical entity Component is part of a group assessment Triclopyr-butoxyethyl ester 265-024-8 64470-88-8 2-Butoxyethyl 2-(3,5,6-trichloropyridin-2-yl)oxyacetate Triclopyr-butoxyethyl ester C13H16Cl3NO4 CCCCOCCOC(=O)COC1=NC(=C(C=C1Cl)Cl)Cl InChI=1S/C13H16Cl3NO4/c1-2-3-4-19-5-6-20-11(18)8-21-13-10(15)7-9(14)12(16)17-13/h7H,2-6,8H2,1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes, concurrent vehicle no data Negative RMS: Ireland Triclopyr 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr 19Jan2006 2006 doi:10.2903/j.efsa.2006.56r
+Triclopyr 259-597-3 55335-06-3 single chemical entity Component is part of a group assessment Triclopyr-butoxyethyl ester 265-024-8 64470-88-8 2-Butoxyethyl 2-(3,5,6-trichloropyridin-2-yl)oxyacetate Triclopyr-butoxyethyl ester C13H16Cl3NO4 CCCCOCCOC(=O)COC1=NC(=C(C=C1Cl)Cl)Cl InChI=1S/C13H16Cl3NO4/c1-2-3-4-19-5-6-20-11(18)8-21-13-10(15)7-9(14)12(16)17-13/h7H,2-6,8H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Ireland Triclopyr 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr 19Jan2006 2006 doi:10.2903/j.efsa.2006.56r
+Triclopyr 259-597-3 55335-06-3 single chemical entity Component is part of a group assessment Triclopyr-butoxyethyl ester 265-024-8 64470-88-8 2-Butoxyethyl 2-(3,5,6-trichloropyridin-2-yl)oxyacetate Triclopyr-butoxyethyl ester C13H16Cl3NO4 CCCCOCCOC(=O)COC1=NC(=C(C=C1Cl)Cl)Cl InChI=1S/C13H16Cl3NO4/c1-2-3-4-19-5-6-20-11(18)8-21-13-10(15)7-9(14)12(16)17-13/h7H,2-6,8H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Ireland Triclopyr 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr 19Jan2006 2006 doi:10.2903/j.efsa.2006.56r
+Triclopyr 259-597-3 55335-06-3 single chemical entity Component is part of a group assessment Triclopyr-butoxyethyl ester 265-024-8 64470-88-8 2-Butoxyethyl 2-(3,5,6-trichloropyridin-2-yl)oxyacetate Triclopyr-butoxyethyl ester C13H16Cl3NO4 CCCCOCCOC(=O)COC1=NC(=C(C=C1Cl)Cl)Cl InChI=1S/C13H16Cl3NO4/c1-2-3-4-19-5-6-20-11(18)8-21-13-10(15)7-9(14)12(16)17-13/h7H,2-6,8H2,1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M17 Not reported yes, concurrent vehicle no data Negative RMS: Ireland Triclopyr 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr 19Jan2006 2006 doi:10.2903/j.efsa.2006.56r
+Triclopyr 259-597-3 55335-06-3 single chemical entity Component is part of a group assessment Triclopyr-butoxyethyl ester 265-024-8 64470-88-8 2-Butoxyethyl 2-(3,5,6-trichloropyridin-2-yl)oxyacetate Triclopyr-butoxyethyl ester C13H16Cl3NO4 CCCCOCCOC(=O)COC1=NC(=C(C=C1Cl)Cl)Cl InChI=1S/C13H16Cl3NO4/c1-2-3-4-19-5-6-20-11(18)8-21-13-10(15)7-9(14)12(16)17-13/h7H,2-6,8H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Ireland Triclopyr 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr 19Jan2006 2006 doi:10.2903/j.efsa.2006.56r
+Triclopyr 259-597-3 55335-06-3 single chemical entity Component is part of a group assessment Triclopyr-butoxyethyl ester 265-024-8 64470-88-8 2-Butoxyethyl 2-(3,5,6-trichloropyridin-2-yl)oxyacetate Triclopyr-butoxyethyl ester C13H16Cl3NO4 CCCCOCCOC(=O)COC1=NC(=C(C=C1Cl)Cl)Cl InChI=1S/C13H16Cl3NO4/c1-2-3-4-19-5-6-20-11(18)8-21-13-10(15)7-9(14)12(16)17-13/h7H,2-6,8H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Ireland Triclopyr 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr 19Jan2006 2006 doi:10.2903/j.efsa.2006.56r
+Triclopyr 259-597-3 55335-06-3 single chemical entity Component is part of a group assessment Triclopyr-butoxyethyl ester 265-024-8 64470-88-8 2-Butoxyethyl 2-(3,5,6-trichloropyridin-2-yl)oxyacetate Triclopyr-butoxyethyl ester C13H16Cl3NO4 CCCCOCCOC(=O)COC1=NC(=C(C=C1Cl)Cl)Cl InChI=1S/C13H16Cl3NO4/c1-2-3-4-19-5-6-20-11(18)8-21-13-10(15)7-9(14)12(16)17-13/h7H,2-6,8H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Ireland Triclopyr 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr 19Jan2006 2006 doi:10.2903/j.efsa.2006.56r
+Triclopyr 259-597-3 55335-06-3 single chemical entity Component is part of a group assessment Triclopyr-butoxyethyl ester 265-024-8 64470-88-8 2-Butoxyethyl 2-(3,5,6-trichloropyridin-2-yl)oxyacetate Triclopyr-butoxyethyl ester C13H16Cl3NO4 CCCCOCCOC(=O)COC1=NC(=C(C=C1Cl)Cl)Cl InChI=1S/C13H16Cl3NO4/c1-2-3-4-19-5-6-20-11(18)8-21-13-10(15)7-9(14)12(16)17-13/h7H,2-6,8H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Ireland Triclopyr 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr 19Jan2006 2006 doi:10.2903/j.efsa.2006.56r
+Triclopyr 259-597-3 55335-06-3 single chemical entity Component is part of a group assessment Triclopyr-butoxyethyl ester 265-024-8 64470-88-8 2-Butoxyethyl 2-(3,5,6-trichloropyridin-2-yl)oxyacetate Triclopyr-butoxyethyl ester C13H16Cl3NO4 CCCCOCCOC(=O)COC1=NC(=C(C=C1Cl)Cl)Cl InChI=1S/C13H16Cl3NO4/c1-2-3-4-19-5-6-20-11(18)8-21-13-10(15)7-9(14)12(16)17-13/h7H,2-6,8H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Ireland Triclopyr 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr 19Jan2006 2006 doi:10.2903/j.efsa.2006.56r
+Triclopyr 259-597-3 55335-06-3 single chemical entity Component is part of a group assessment Triclopyr-butoxyethyl ester 265-024-8 64470-88-8 2-Butoxyethyl 2-(3,5,6-trichloropyridin-2-yl)oxyacetate Triclopyr-butoxyethyl ester C13H16Cl3NO4 CCCCOCCOC(=O)COC1=NC(=C(C=C1Cl)Cl)Cl InChI=1S/C13H16Cl3NO4/c1-2-3-4-19-5-6-20-11(18)8-21-13-10(15)7-9(14)12(16)17-13/h7H,2-6,8H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Ireland Triclopyr 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr 19Jan2006 2006 doi:10.2903/j.efsa.2006.56r
+Triclopyr 259-597-3 55335-06-3 single chemical entity Component is part of a group assessment Triclopyr-butoxyethyl ester 265-024-8 64470-88-8 2-Butoxyethyl 2-(3,5,6-trichloropyridin-2-yl)oxyacetate Triclopyr-butoxyethyl ester C13H16Cl3NO4 CCCCOCCOC(=O)COC1=NC(=C(C=C1Cl)Cl)Cl InChI=1S/C13H16Cl3NO4/c1-2-3-4-19-5-6-20-11(18)8-21-13-10(15)7-9(14)12(16)17-13/h7H,2-6,8H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Ireland Triclopyr 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr 19Jan2006 2006 doi:10.2903/j.efsa.2006.56r
+Triclopyr 259-597-3 55335-06-3 single chemical entity Component is part of a group assessment Triclopyr-butoxyethyl ester 265-024-8 64470-88-8 2-Butoxyethyl 2-(3,5,6-trichloropyridin-2-yl)oxyacetate Triclopyr-butoxyethyl ester C13H16Cl3NO4 CCCCOCCOC(=O)COC1=NC(=C(C=C1Cl)Cl)Cl InChI=1S/C13H16Cl3NO4/c1-2-3-4-19-5-6-20-11(18)8-21-13-10(15)7-9(14)12(16)17-13/h7H,2-6,8H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Ireland Triclopyr 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr 19Jan2006 2006 doi:10.2903/j.efsa.2006.56r
+Triclopyr 259-597-3 55335-06-3 single chemical entity Component is part of a group assessment Triclopyr-butoxyethyl ester 265-024-8 64470-88-8 2-Butoxyethyl 2-(3,5,6-trichloropyridin-2-yl)oxyacetate Triclopyr-butoxyethyl ester C13H16Cl3NO4 CCCCOCCOC(=O)COC1=NC(=C(C=C1Cl)Cl)Cl InChI=1S/C13H16Cl3NO4/c1-2-3-4-19-5-6-20-11(18)8-21-13-10(15)7-9(14)12(16)17-13/h7H,2-6,8H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: Ireland Triclopyr 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr 19Jan2006 2006 doi:10.2903/j.efsa.2006.56r
+Triclopyr 259-597-3 55335-06-3 single chemical entity Component is part of a group assessment Triclopyr-butoxyethyl ester 265-024-8 64470-88-8 2-Butoxyethyl 2-(3,5,6-trichloropyridin-2-yl)oxyacetate Triclopyr-butoxyethyl ester C13H16Cl3NO4 CCCCOCCOC(=O)COC1=NC(=C(C=C1Cl)Cl)Cl InChI=1S/C13H16Cl3NO4/c1-2-3-4-19-5-6-20-11(18)8-21-13-10(15)7-9(14)12(16)17-13/h7H,2-6,8H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: Ireland Triclopyr 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr 19Jan2006 2006 doi:10.2903/j.efsa.2006.56r
+Triclopyr 259-597-3 55335-06-3 single chemical entity Component is identical to the substance Triclopyr 259-597-3 55335-06-3 [(3,5,6-trichloropyridin-2-yl)oxy]acetic acid Triclopyr C7H4Cl3NO3 O=C(O)COC1=C(Cl)C=C(Cl)C(Cl)=N1 InChI=1S/C7H4Cl3NO3/c8-3-1-4(9)7(11-6(3)10)14-2-5(12)13/h1H,2H2,(H,12,13) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Ireland Triclopyr 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr 19Jan2006 2006 doi:10.2903/j.efsa.2006.56r
+Triclopyr 259-597-3 55335-06-3 single chemical entity Component is identical to the substance Triclopyr 259-597-3 55335-06-3 [(3,5,6-trichloropyridin-2-yl)oxy]acetic acid Triclopyr C7H4Cl3NO3 O=C(O)COC1=C(Cl)C=C(Cl)C(Cl)=N1 InChI=1S/C7H4Cl3NO3/c8-3-1-4(9)7(11-6(3)10)14-2-5(12)13/h1H,2H2,(H,12,13) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Ireland Triclopyr 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr 19Jan2006 2006 doi:10.2903/j.efsa.2006.56r
+Triclopyr 259-597-3 55335-06-3 single chemical entity Component is identical to the substance Triclopyr 259-597-3 55335-06-3 [(3,5,6-trichloropyridin-2-yl)oxy]acetic acid Triclopyr C7H4Cl3NO3 O=C(O)COC1=C(Cl)C=C(Cl)C(Cl)=N1 InChI=1S/C7H4Cl3NO3/c8-3-1-4(9)7(11-6(3)10)14-2-5(12)13/h1H,2H2,(H,12,13) organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Ireland Triclopyr 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr 19Jan2006 2006 doi:10.2903/j.efsa.2006.56r
+Triclopyr 259-597-3 55335-06-3 single chemical entity Component is part of a group assessment Triclopyr-butoxyethyl ester 265-024-8 64470-88-8 2-Butoxyethyl 2-(3,5,6-trichloropyridin-2-yl)oxyacetate Triclopyr-butoxyethyl ester C13H16Cl3NO4 CCCCOCCOC(=O)COC1=NC(=C(C=C1Cl)Cl)Cl InChI=1S/C13H16Cl3NO4/c1-2-3-4-19-5-6-20-11(18)8-21-13-10(15)7-9(14)12(16)17-13/h7H,2-6,8H2,1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Ireland Triclopyr 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr 19Jan2006 2006 doi:10.2903/j.efsa.2006.56r
+Triclopyr 259-597-3 55335-06-3 single chemical entity Component is identical to the substance Triclopyr 259-597-3 55335-06-3 [(3,5,6-trichloropyridin-2-yl)oxy]acetic acid Triclopyr C7H4Cl3NO3 O=C(O)COC1=C(Cl)C=C(Cl)C(Cl)=N1 InChI=1S/C7H4Cl3NO3/c8-3-1-4(9)7(11-6(3)10)14-2-5(12)13/h1H,2H2,(H,12,13) organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Sprague-Dawley 5 Male oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Ireland Triclopyr 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr 19Jan2006 2006 doi:10.2903/j.efsa.2006.56r
+Triclopyr 259-597-3 55335-06-3 single chemical entity Component is identical to the substance Triclopyr 259-597-3 55335-06-3 [(3,5,6-trichloropyridin-2-yl)oxy]acetic acid Triclopyr C7H4Cl3NO3 O=C(O)COC1=C(Cl)C=C(Cl)C(Cl)=N1 InChI=1S/C7H4Cl3NO3/c8-3-1-4(9)7(11-6(3)10)14-2-5(12)13/h1H,2H2,(H,12,13) organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Sprague-Dawley 5 Male oral: unspecified 48.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Ireland Triclopyr 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr 19Jan2006 2006 doi:10.2903/j.efsa.2006.56r
+Triclopyr 259-597-3 55335-06-3 single chemical entity Component is identical to the substance Triclopyr 259-597-3 55335-06-3 [(3,5,6-trichloropyridin-2-yl)oxy]acetic acid Triclopyr C7H4Cl3NO3 O=C(O)COC1=C(Cl)C=C(Cl)C(Cl)=N1 InChI=1S/C7H4Cl3NO3/c8-3-1-4(9)7(11-6(3)10)14-2-5(12)13/h1H,2H2,(H,12,13) organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Sprague-Dawley 5 Male oral: unspecified 6.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Ireland Triclopyr 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr 19Jan2006 2006 doi:10.2903/j.efsa.2006.56r
+Triclopyr 259-597-3 55335-06-3 single chemical entity Component is identical to the substance Triclopyr 259-597-3 55335-06-3 [(3,5,6-trichloropyridin-2-yl)oxy]acetic acid Triclopyr C7H4Cl3NO3 O=C(O)COC1=C(Cl)C=C(Cl)C(Cl)=N1 InChI=1S/C7H4Cl3NO3/c8-3-1-4(9)7(11-6(3)10)14-2-5(12)13/h1H,2H2,(H,12,13) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) ICR 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Ireland Triclopyr 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr 19Jan2006 2006 doi:10.2903/j.efsa.2006.56r
+Triclopyr 259-597-3 55335-06-3 single chemical entity Component is identical to the substance Triclopyr 259-597-3 55335-06-3 [(3,5,6-trichloropyridin-2-yl)oxy]acetic acid Triclopyr C7H4Cl3NO3 O=C(O)COC1=C(Cl)C=C(Cl)C(Cl)=N1 InChI=1S/C7H4Cl3NO3/c8-3-1-4(9)7(11-6(3)10)14-2-5(12)13/h1H,2H2,(H,12,13) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) ICR 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Ireland Triclopyr 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr 19Jan2006 2006 doi:10.2903/j.efsa.2006.56r
+Triclopyr 259-597-3 55335-06-3 single chemical entity Component is part of a group assessment Triclopyr-butoxyethyl ester 265-024-8 64470-88-8 2-Butoxyethyl 2-(3,5,6-trichloropyridin-2-yl)oxyacetate Triclopyr-butoxyethyl ester C13H16Cl3NO4 CCCCOCCOC(=O)COC1=NC(=C(C=C1Cl)Cl)Cl InChI=1S/C13H16Cl3NO4/c1-2-3-4-19-5-6-20-11(18)8-21-13-10(15)7-9(14)12(16)17-13/h7H,2-6,8H2,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) ICR 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity RMS: Ireland Triclopyr 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr 19Jan2006 2006 doi:10.2903/j.efsa.2006.56r
+Triclopyr 259-597-3 55335-06-3 single chemical entity Component is part of a group assessment Triclopyr-butoxyethyl ester 265-024-8 64470-88-8 2-Butoxyethyl 2-(3,5,6-trichloropyridin-2-yl)oxyacetate Triclopyr-butoxyethyl ester C13H16Cl3NO4 CCCCOCCOC(=O)COC1=NC(=C(C=C1Cl)Cl)Cl InChI=1S/C13H16Cl3NO4/c1-2-3-4-19-5-6-20-11(18)8-21-13-10(15)7-9(14)12(16)17-13/h7H,2-6,8H2,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) ICR 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity RMS: Ireland Triclopyr 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr 19Jan2006 2006 doi:10.2903/j.efsa.2006.56r
+Triclopyr 259-597-3 55335-06-3 single chemical entity Component is part of a group assessment Triclopyr-butoxyethyl ester 265-024-8 64470-88-8 2-Butoxyethyl 2-(3,5,6-trichloropyridin-2-yl)oxyacetate Triclopyr-butoxyethyl ester C13H16Cl3NO4 CCCCOCCOC(=O)COC1=NC(=C(C=C1Cl)Cl)Cl InChI=1S/C13H16Cl3NO4/c1-2-3-4-19-5-6-20-11(18)8-21-13-10(15)7-9(14)12(16)17-13/h7H,2-6,8H2,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) ICR 10 Male/Female oral: gavage 72.0000000000 h yes, concurrent vehicle not applicable Negative direct evidence-cytotoxicity RMS: Ireland Triclopyr 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr 19Jan2006 2006 doi:10.2903/j.efsa.2006.56r
+Triclopyr 259-597-3 55335-06-3 single chemical entity Component is identical to the substance Triclopyr 259-597-3 55335-06-3 [(3,5,6-trichloropyridin-2-yl)oxy]acetic acid Triclopyr C7H4Cl3NO3 O=C(O)COC1=C(Cl)C=C(Cl)C(Cl)=N1 InChI=1S/C7H4Cl3NO3/c8-3-1-4(9)7(11-6(3)10)14-2-5(12)13/h1H,2H2,(H,12,13) organic compound Other Other chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) Yes Acceptable House mouse (as animal) CF-1 30 Male oral: feed 9.0000000000 week yes not applicable Negative RMS: Ireland Triclopyr 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr 19Jan2006 2006 doi:10.2903/j.efsa.2006.56r
+Triclopyr 259-597-3 55335-06-3 single chemical entity Component is a metabolite of the substance 3,5,6-Trichloro-2-pyridinol 229-405-2 6515-38-4 3,5,6-trichloro-1H-pyridin-2-one Not in list C5H2Cl3NO C1=C(C(=O)NC(=C1Cl)Cl)Cl InChI=1S/C5H2Cl3NO/c6-2-1-3(7)5(10)9-4(2)8/h1H,(H,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Ireland Triclopyr 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr 19Jan2006 2006 doi:10.2903/j.efsa.2006.56r
+Triclopyr 259-597-3 55335-06-3 single chemical entity Component is a metabolite of the substance 3,5,6-Trichloro-2-pyridinol 229-405-2 6515-38-4 3,5,6-trichloro-1H-pyridin-2-one Not in list C5H2Cl3NO C1=C(C(=O)NC(=C1Cl)Cl)Cl InChI=1S/C5H2Cl3NO/c6-2-1-3(7)5(10)9-4(2)8/h1H,(H,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Ireland Triclopyr 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr 19Jan2006 2006 doi:10.2903/j.efsa.2006.56r
+Triclopyr 259-597-3 55335-06-3 single chemical entity Component is a metabolite of the substance 3,5,6-Trichloro-2-pyridinol 229-405-2 6515-38-4 3,5,6-trichloro-1H-pyridin-2-one Not in list C5H2Cl3NO C1=C(C(=O)NC(=C1Cl)Cl)Cl InChI=1S/C5H2Cl3NO/c6-2-1-3(7)5(10)9-4(2)8/h1H,(H,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Ireland Triclopyr 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr 19Jan2006 2006 doi:10.2903/j.efsa.2006.56r
+Triclopyr 259-597-3 55335-06-3 single chemical entity Component is a metabolite of the substance 3,5,6-Trichloro-2-pyridinol 229-405-2 6515-38-4 3,5,6-trichloro-1H-pyridin-2-one Not in list C5H2Cl3NO C1=C(C(=O)NC(=C1Cl)Cl)Cl InChI=1S/C5H2Cl3NO/c6-2-1-3(7)5(10)9-4(2)8/h1H,(H,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Ireland Triclopyr 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr 19Jan2006 2006 doi:10.2903/j.efsa.2006.56r
+Triclopyr 259-597-3 55335-06-3 single chemical entity Component is a metabolite of the substance 3,5,6-Trichloro-2-pyridinol 229-405-2 6515-38-4 3,5,6-trichloro-1H-pyridin-2-one Not in list C5H2Cl3NO C1=C(C(=O)NC(=C1Cl)Cl)Cl InChI=1S/C5H2Cl3NO/c6-2-1-3(7)5(10)9-4(2)8/h1H,(H,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Ireland Triclopyr 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr 19Jan2006 2006 doi:10.2903/j.efsa.2006.56r
+Triclopyr 259-597-3 55335-06-3 single chemical entity Component is a metabolite of the substance 3,5,6-Trichloro-2-pyridinol 229-405-2 6515-38-4 3,5,6-trichloro-1H-pyridin-2-one Not in list C5H2Cl3NO C1=C(C(=O)NC(=C1Cl)Cl)Cl InChI=1S/C5H2Cl3NO/c6-2-1-3(7)5(10)9-4(2)8/h1H,(H,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Ireland Triclopyr 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr 19Jan2006 2006 doi:10.2903/j.efsa.2006.56r
+Triclopyr 259-597-3 55335-06-3 single chemical entity Component is a metabolite of the substance 3,5,6-Trichloro-2-pyridinol 229-405-2 6515-38-4 3,5,6-trichloro-1H-pyridin-2-one Not in list C5H2Cl3NO C1=C(C(=O)NC(=C1Cl)Cl)Cl InChI=1S/C5H2Cl3NO/c6-2-1-3(7)5(10)9-4(2)8/h1H,(H,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Ireland Triclopyr 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr 19Jan2006 2006 doi:10.2903/j.efsa.2006.56r
+Triclopyr 259-597-3 55335-06-3 single chemical entity Component is a metabolite of the substance 3,5,6-Trichloro-2-pyridinol 229-405-2 6515-38-4 3,5,6-trichloro-1H-pyridin-2-one Not in list C5H2Cl3NO C1=C(C(=O)NC(=C1Cl)Cl)Cl InChI=1S/C5H2Cl3NO/c6-2-1-3(7)5(10)9-4(2)8/h1H,(H,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Ireland Triclopyr 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr 19Jan2006 2006 doi:10.2903/j.efsa.2006.56r
+Triclopyr 259-597-3 55335-06-3 single chemical entity Component is a metabolite of the substance 3,5,6-Trichloro-2-pyridinol 229-405-2 6515-38-4 3,5,6-trichloro-1H-pyridin-2-one Not in list C5H2Cl3NO C1=C(C(=O)NC(=C1Cl)Cl)Cl InChI=1S/C5H2Cl3NO/c6-2-1-3(7)5(10)9-4(2)8/h1H,(H,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Ireland Triclopyr 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr 19Jan2006 2006 doi:10.2903/j.efsa.2006.56r
+Triclopyr 259-597-3 55335-06-3 single chemical entity Component is a metabolite of the substance 3,5,6-Trichloro-2-pyridinol 229-405-2 6515-38-4 3,5,6-trichloro-1H-pyridin-2-one Not in list C5H2Cl3NO C1=C(C(=O)NC(=C1Cl)Cl)Cl InChI=1S/C5H2Cl3NO/c6-2-1-3(7)5(10)9-4(2)8/h1H,(H,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Ireland Triclopyr 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr 19Jan2006 2006 doi:10.2903/j.efsa.2006.56r
+Triclopyr 259-597-3 55335-06-3 single chemical entity Component is a metabolite of the substance 3,5,6-Trichloro-2-pyridinol 229-405-2 6515-38-4 3,5,6-trichloro-1H-pyridin-2-one Not in list C5H2Cl3NO C1=C(C(=O)NC(=C1Cl)Cl)Cl InChI=1S/C5H2Cl3NO/c6-2-1-3(7)5(10)9-4(2)8/h1H,(H,9,10) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Ireland Triclopyr 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr 19Jan2006 2006 doi:10.2903/j.efsa.2006.56r
+Triclopyr 259-597-3 55335-06-3 single chemical entity Component is a metabolite of the substance 3,5,6-Trichloro-2-pyridinol 229-405-2 6515-38-4 3,5,6-trichloro-1H-pyridin-2-one Not in list C5H2Cl3NO C1=C(C(=O)NC(=C1Cl)Cl)Cl InChI=1S/C5H2Cl3NO/c6-2-1-3(7)5(10)9-4(2)8/h1H,(H,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Ireland Triclopyr 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr 19Jan2006 2006 doi:10.2903/j.efsa.2006.56r
+Triclopyr 259-597-3 55335-06-3 single chemical entity Component is a metabolite of the substance 3,5,6-Trichloro-2-pyridinol 229-405-2 6515-38-4 3,5,6-trichloro-1H-pyridin-2-one Not in list C5H2Cl3NO C1=C(C(=O)NC(=C1Cl)Cl)Cl InChI=1S/C5H2Cl3NO/c6-2-1-3(7)5(10)9-4(2)8/h1H,(H,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Ireland Triclopyr 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr 19Jan2006 2006 doi:10.2903/j.efsa.2006.56r
+Triclopyr 259-597-3 55335-06-3 single chemical entity Component is a metabolite of the substance 3,5,6-Trichloro-2-pyridinol 229-405-2 6515-38-4 3,5,6-trichloro-1H-pyridin-2-one Not in list C5H2Cl3NO C1=C(C(=O)NC(=C1Cl)Cl)Cl InChI=1S/C5H2Cl3NO/c6-2-1-3(7)5(10)9-4(2)8/h1H,(H,9,10) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) ICR 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Ireland Triclopyr 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr 19Jan2006 2006 doi:10.2903/j.efsa.2006.56r
+Triclopyr 259-597-3 55335-06-3 single chemical entity Component is a metabolite of the substance 3,5,6-Trichloro-2-pyridinol 229-405-2 6515-38-4 3,5,6-trichloro-1H-pyridin-2-one Not in list C5H2Cl3NO C1=C(C(=O)NC(=C1Cl)Cl)Cl InChI=1S/C5H2Cl3NO/c6-2-1-3(7)5(10)9-4(2)8/h1H,(H,9,10) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) ICR 10 Male/Female oral: gavage 72.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Ireland Triclopyr 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr 19Jan2006 2006 doi:10.2903/j.efsa.2006.56r
+Triclopyr 259-597-3 55335-06-3 single chemical entity Component is a metabolite of the substance 3,5,6-Trichloro-2-pyridinol 229-405-2 6515-38-4 3,5,6-trichloro-1H-pyridin-2-one Not in list C5H2Cl3NO C1=C(C(=O)NC(=C1Cl)Cl)Cl InChI=1S/C5H2Cl3NO/c6-2-1-3(7)5(10)9-4(2)8/h1H,(H,9,10) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) ICR 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Ireland Triclopyr 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr 19Jan2006 2006 doi:10.2903/j.efsa.2006.56r
+Triclopyr 259-597-3 55335-06-3 single chemical entity Component is a metabolite of the substance 3,5,6-Trichloro-2-pyridinol 229-405-2 6515-38-4 3,5,6-trichloro-1H-pyridin-2-one Not in list C5H2Cl3NO C1=C(C(=O)NC(=C1Cl)Cl)Cl InChI=1S/C5H2Cl3NO/c6-2-1-3(7)5(10)9-4(2)8/h1H,(H,9,10) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) ICR 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Ireland Triclopyr 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr 19Jan2006 2006 doi:10.2903/j.efsa.2006.56r
+Triclopyr 259-597-3 55335-06-3 single chemical entity Component is a metabolite of the substance 3,5,6-Trichloro-2-pyridinol 229-405-2 6515-38-4 3,5,6-trichloro-1H-pyridin-2-one Not in list C5H2Cl3NO C1=C(C(=O)NC(=C1Cl)Cl)Cl InChI=1S/C5H2Cl3NO/c6-2-1-3(7)5(10)9-4(2)8/h1H,(H,9,10) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) ICR 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Ireland Triclopyr 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr 19Jan2006 2006 doi:10.2903/j.efsa.2006.56r
+Triflumizole 99387-89-0 single chemical entity Component is identical to the substance Triflumizole 99387-89-0 N-[4-chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine Triflumizole C15H15ClF3N3O CCCOCC(=NC1=C(C=C(C=C1)Cl)C(F)(F)F)N2C=CN=C2 InChI=1S/C15H15ClF3N3O/c1-2-7-23-9-14(22-6-5-20-10-22)21-13-4-3-11(16)8-12(13)15(17,18)19/h3-6,8,10H,2,7,9H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Triflumizole 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumizole 14Dec2009 2009 doi:10.2903/j.efsa.2009.1415
+Triflumizole 99387-89-0 single chemical entity Component is identical to the substance Triflumizole 99387-89-0 N-[4-chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine Triflumizole C15H15ClF3N3O CCCOCC(=NC1=C(C=C(C=C1)Cl)C(F)(F)F)N2C=CN=C2 InChI=1S/C15H15ClF3N3O/c1-2-7-23-9-14(22-6-5-20-10-22)21-13-4-3-11(16)8-12(13)15(17,18)19/h3-6,8,10H,2,7,9H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Triflumizole 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumizole 14Dec2009 2009 doi:10.2903/j.efsa.2009.1415
+Triflumizole 99387-89-0 single chemical entity Component is identical to the substance Triflumizole 99387-89-0 N-[4-chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine Triflumizole C15H15ClF3N3O CCCOCC(=NC1=C(C=C(C=C1)Cl)C(F)(F)F)N2C=CN=C2 InChI=1S/C15H15ClF3N3O/c1-2-7-23-9-14(22-6-5-20-10-22)21-13-4-3-11(16)8-12(13)15(17,18)19/h3-6,8,10H,2,7,9H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Triflumizole 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumizole 14Dec2009 2009 doi:10.2903/j.efsa.2009.1415
+Triflumizole 99387-89-0 single chemical entity Component is identical to the substance Triflumizole 99387-89-0 N-[4-chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine Triflumizole C15H15ClF3N3O CCCOCC(=NC1=C(C=C(C=C1)Cl)C(F)(F)F)N2C=CN=C2 InChI=1S/C15H15ClF3N3O/c1-2-7-23-9-14(22-6-5-20-10-22)21-13-4-3-11(16)8-12(13)15(17,18)19/h3-6,8,10H,2,7,9H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Triflumizole 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumizole 14Dec2009 2009 doi:10.2903/j.efsa.2009.1415
+Triflumizole 99387-89-0 single chemical entity Component is identical to the substance Triflumizole 99387-89-0 N-[4-chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine Triflumizole C15H15ClF3N3O CCCOCC(=NC1=C(C=C(C=C1)Cl)C(F)(F)F)N2C=CN=C2 InChI=1S/C15H15ClF3N3O/c1-2-7-23-9-14(22-6-5-20-10-22)21-13-4-3-11(16)8-12(13)15(17,18)19/h3-6,8,10H,2,7,9H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Triflumizole 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumizole 14Dec2009 2009 doi:10.2903/j.efsa.2009.1415
+Triflumizole 99387-89-0 single chemical entity Component is identical to the substance Triflumizole 99387-89-0 N-[4-chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine Triflumizole C15H15ClF3N3O CCCOCC(=NC1=C(C=C(C=C1)Cl)C(F)(F)F)N2C=CN=C2 InChI=1S/C15H15ClF3N3O/c1-2-7-23-9-14(22-6-5-20-10-22)21-13-4-3-11(16)8-12(13)15(17,18)19/h3-6,8,10H,2,7,9H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Triflumizole 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumizole 14Dec2009 2009 doi:10.2903/j.efsa.2009.1415
+Triflumizole 99387-89-0 single chemical entity Component is identical to the substance Triflumizole 99387-89-0 N-[4-chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine Triflumizole C15H15ClF3N3O CCCOCC(=NC1=C(C=C(C=C1)Cl)C(F)(F)F)N2C=CN=C2 InChI=1S/C15H15ClF3N3O/c1-2-7-23-9-14(22-6-5-20-10-22)21-13-4-3-11(16)8-12(13)15(17,18)19/h3-6,8,10H,2,7,9H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Triflumizole 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumizole 14Dec2009 2009 doi:10.2903/j.efsa.2009.1415
+Triflumizole 99387-89-0 single chemical entity Component is identical to the substance Triflumizole 99387-89-0 N-[4-chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine Triflumizole C15H15ClF3N3O CCCOCC(=NC1=C(C=C(C=C1)Cl)C(F)(F)F)N2C=CN=C2 InChI=1S/C15H15ClF3N3O/c1-2-7-23-9-14(22-6-5-20-10-22)21-13-4-3-11(16)8-12(13)15(17,18)19/h3-6,8,10H,2,7,9H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Triflumizole 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumizole 14Dec2009 2009 doi:10.2903/j.efsa.2009.1415
+Triflumizole 99387-89-0 single chemical entity Component is identical to the substance Triflumizole 99387-89-0 N-[4-chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine Triflumizole C15H15ClF3N3O CCCOCC(=NC1=C(C=C(C=C1)Cl)C(F)(F)F)N2C=CN=C2 InChI=1S/C15H15ClF3N3O/c1-2-7-23-9-14(22-6-5-20-10-22)21-13-4-3-11(16)8-12(13)15(17,18)19/h3-6,8,10H,2,7,9H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Triflumizole 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumizole 14Dec2009 2009 doi:10.2903/j.efsa.2009.1415
+Triflumizole 99387-89-0 single chemical entity Component is identical to the substance Triflumizole 99387-89-0 N-[4-chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine Triflumizole C15H15ClF3N3O CCCOCC(=NC1=C(C=C(C=C1)Cl)C(F)(F)F)N2C=CN=C2 InChI=1S/C15H15ClF3N3O/c1-2-7-23-9-14(22-6-5-20-10-22)21-13-4-3-11(16)8-12(13)15(17,18)19/h3-6,8,10H,2,7,9H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Triflumizole 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumizole 14Dec2009 2009 doi:10.2903/j.efsa.2009.1415
+Triflumizole 99387-89-0 single chemical entity Component is identical to the substance Triflumizole 99387-89-0 N-[4-chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine Triflumizole C15H15ClF3N3O CCCOCC(=NC1=C(C=C(C=C1)Cl)C(F)(F)F)N2C=CN=C2 InChI=1S/C15H15ClF3N3O/c1-2-7-23-9-14(22-6-5-20-10-22)21-13-4-3-11(16)8-12(13)15(17,18)19/h3-6,8,10H,2,7,9H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Triflumizole 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumizole 14Dec2009 2009 doi:10.2903/j.efsa.2009.1415
+Triflumizole 99387-89-0 single chemical entity Component is identical to the substance Triflumizole 99387-89-0 N-[4-chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine Triflumizole C15H15ClF3N3O CCCOCC(=NC1=C(C=C(C=C1)Cl)C(F)(F)F)N2C=CN=C2 InChI=1S/C15H15ClF3N3O/c1-2-7-23-9-14(22-6-5-20-10-22)21-13-4-3-11(16)8-12(13)15(17,18)19/h3-6,8,10H,2,7,9H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Triflumizole 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumizole 14Dec2009 2009 doi:10.2903/j.efsa.2009.1415
+Triflumizole 99387-89-0 single chemical entity Component is identical to the substance Triflumizole 99387-89-0 N-[4-chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine Triflumizole C15H15ClF3N3O CCCOCC(=NC1=C(C=C(C=C1)Cl)C(F)(F)F)N2C=CN=C2 InChI=1S/C15H15ClF3N3O/c1-2-7-23-9-14(22-6-5-20-10-22)21-13-4-3-11(16)8-12(13)15(17,18)19/h3-6,8,10H,2,7,9H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Triflumizole 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumizole 14Dec2009 2009 doi:10.2903/j.efsa.2009.1415
+Triflumizole 99387-89-0 single chemical entity Component is identical to the substance Triflumizole 99387-89-0 N-[4-chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine Triflumizole C15H15ClF3N3O CCCOCC(=NC1=C(C=C(C=C1)Cl)C(F)(F)F)N2C=CN=C2 InChI=1S/C15H15ClF3N3O/c1-2-7-23-9-14(22-6-5-20-10-22)21-13-4-3-11(16)8-12(13)15(17,18)19/h3-6,8,10H,2,7,9H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Triflumizole 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumizole 14Dec2009 2009 doi:10.2903/j.efsa.2009.1415
+Triflumizole 99387-89-0 single chemical entity Component is identical to the substance Triflumizole 99387-89-0 N-[4-chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine Triflumizole C15H15ClF3N3O CCCOCC(=NC1=C(C=C(C=C1)Cl)C(F)(F)F)N2C=CN=C2 InChI=1S/C15H15ClF3N3O/c1-2-7-23-9-14(22-6-5-20-10-22)21-13-4-3-11(16)8-12(13)15(17,18)19/h3-6,8,10H,2,7,9H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Triflumizole 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumizole 14Dec2009 2009 doi:10.2903/j.efsa.2009.1415
+Triflumizole 99387-89-0 single chemical entity Component is identical to the substance Triflumizole 99387-89-0 N-[4-chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine Triflumizole C15H15ClF3N3O CCCOCC(=NC1=C(C=C(C=C1)Cl)C(F)(F)F)N2C=CN=C2 InChI=1S/C15H15ClF3N3O/c1-2-7-23-9-14(22-6-5-20-10-22)21-13-4-3-11(16)8-12(13)15(17,18)19/h3-6,8,10H,2,7,9H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Triflumizole 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumizole 14Dec2009 2009 doi:10.2903/j.efsa.2009.1415
+Triflumizole 99387-89-0 single chemical entity Component is identical to the substance Triflumizole 99387-89-0 N-[4-chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine Triflumizole C15H15ClF3N3O CCCOCC(=NC1=C(C=C(C=C1)Cl)C(F)(F)F)N2C=CN=C2 InChI=1S/C15H15ClF3N3O/c1-2-7-23-9-14(22-6-5-20-10-22)21-13-4-3-11(16)8-12(13)15(17,18)19/h3-6,8,10H,2,7,9H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Triflumizole 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumizole 14Dec2009 2009 doi:10.2903/j.efsa.2009.1415
+Triflumizole 99387-89-0 single chemical entity Component is identical to the substance Triflumizole 99387-89-0 N-[4-chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine Triflumizole C15H15ClF3N3O CCCOCC(=NC1=C(C=C(C=C1)Cl)C(F)(F)F)N2C=CN=C2 InChI=1S/C15H15ClF3N3O/c1-2-7-23-9-14(22-6-5-20-10-22)21-13-4-3-11(16)8-12(13)15(17,18)19/h3-6,8,10H,2,7,9H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Triflumizole 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumizole 14Dec2009 2009 doi:10.2903/j.efsa.2009.1415
+Triflumizole 99387-89-0 single chemical entity Component is identical to the substance Triflumizole 99387-89-0 N-[4-chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine Triflumizole C15H15ClF3N3O CCCOCC(=NC1=C(C=C(C=C1)Cl)C(F)(F)F)N2C=CN=C2 InChI=1S/C15H15ClF3N3O/c1-2-7-23-9-14(22-6-5-20-10-22)21-13-4-3-11(16)8-12(13)15(17,18)19/h3-6,8,10H,2,7,9H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Triflumizole 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumizole 14Dec2009 2009 doi:10.2903/j.efsa.2009.1415
+Triflumizole 99387-89-0 single chemical entity Component is identical to the substance Triflumizole 99387-89-0 N-[4-chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine Triflumizole C15H15ClF3N3O CCCOCC(=NC1=C(C=C(C=C1)Cl)C(F)(F)F)N2C=CN=C2 InChI=1S/C15H15ClF3N3O/c1-2-7-23-9-14(22-6-5-20-10-22)21-13-4-3-11(16)8-12(13)15(17,18)19/h3-6,8,10H,2,7,9H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Triflumizole 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumizole 14Dec2009 2009 doi:10.2903/j.efsa.2009.1415
+Triflumizole 99387-89-0 single chemical entity Component is identical to the substance Triflumizole 99387-89-0 N-[4-chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine Triflumizole C15H15ClF3N3O CCCOCC(=NC1=C(C=C(C=C1)Cl)C(F)(F)F)N2C=CN=C2 InChI=1S/C15H15ClF3N3O/c1-2-7-23-9-14(22-6-5-20-10-22)21-13-4-3-11(16)8-12(13)15(17,18)19/h3-6,8,10H,2,7,9H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Triflumizole 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumizole 14Dec2009 2009 doi:10.2903/j.efsa.2009.1415
+Triflumizole 99387-89-0 single chemical entity Component is identical to the substance Triflumizole 99387-89-0 N-[4-chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine Triflumizole C15H15ClF3N3O CCCOCC(=NC1=C(C=C(C=C1)Cl)C(F)(F)F)N2C=CN=C2 InChI=1S/C15H15ClF3N3O/c1-2-7-23-9-14(22-6-5-20-10-22)21-13-4-3-11(16)8-12(13)15(17,18)19/h3-6,8,10H,2,7,9H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Triflumizole 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumizole 14Dec2009 2009 doi:10.2903/j.efsa.2009.1415
+Triflumizole 99387-89-0 single chemical entity Component is identical to the substance Triflumizole 99387-89-0 N-[4-chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine Triflumizole C15H15ClF3N3O CCCOCC(=NC1=C(C=C(C=C1)Cl)C(F)(F)F)N2C=CN=C2 InChI=1S/C15H15ClF3N3O/c1-2-7-23-9-14(22-6-5-20-10-22)21-13-4-3-11(16)8-12(13)15(17,18)19/h3-6,8,10H,2,7,9H2,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Triflumizole 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumizole 14Dec2009 2009 doi:10.2903/j.efsa.2009.1415
+Triflumizole 99387-89-0 single chemical entity Component is identical to the substance Triflumizole 99387-89-0 N-[4-chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine Triflumizole C15H15ClF3N3O CCCOCC(=NC1=C(C=C(C=C1)Cl)C(F)(F)F)N2C=CN=C2 InChI=1S/C15H15ClF3N3O/c1-2-7-23-9-14(22-6-5-20-10-22)21-13-4-3-11(16)8-12(13)15(17,18)19/h3-6,8,10H,2,7,9H2,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Triflumizole 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumizole 14Dec2009 2009 doi:10.2903/j.efsa.2009.1415
+Triflumizole 99387-89-0 single chemical entity Component is identical to the substance Triflumizole 99387-89-0 N-[4-chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine Triflumizole C15H15ClF3N3O CCCOCC(=NC1=C(C=C(C=C1)Cl)C(F)(F)F)N2C=CN=C2 InChI=1S/C15H15ClF3N3O/c1-2-7-23-9-14(22-6-5-20-10-22)21-13-4-3-11(16)8-12(13)15(17,18)19/h3-6,8,10H,2,7,9H2,1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported no data without Negative RMS: The Netherlands Triflumizole 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumizole 14Dec2009 2009 doi:10.2903/j.efsa.2009.1415
+Triflumizole 99387-89-0 single chemical entity Component is identical to the substance Triflumizole 99387-89-0 N-[4-chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine Triflumizole C15H15ClF3N3O CCCOCC(=NC1=C(C=C(C=C1)Cl)C(F)(F)F)N2C=CN=C2 InChI=1S/C15H15ClF3N3O/c1-2-7-23-9-14(22-6-5-20-10-22)21-13-4-3-11(16)8-12(13)15(17,18)19/h3-6,8,10H,2,7,9H2,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 48.0000000000 h no data not applicable Negative indirect evidence-systemic toxicity RMS: The Netherlands Triflumizole 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumizole 14Dec2009 2009 doi:10.2903/j.efsa.2009.1415
+Triflumizole 99387-89-0 single chemical entity Component is identical to the substance Triflumizole 99387-89-0 N-[4-chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine Triflumizole C15H15ClF3N3O CCCOCC(=NC1=C(C=C(C=C1)Cl)C(F)(F)F)N2C=CN=C2 InChI=1S/C15H15ClF3N3O/c1-2-7-23-9-14(22-6-5-20-10-22)21-13-4-3-11(16)8-12(13)15(17,18)19/h3-6,8,10H,2,7,9H2,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h no data not applicable Negative indirect evidence-systemic toxicity RMS: The Netherlands Triflumizole 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumizole 14Dec2009 2009 doi:10.2903/j.efsa.2009.1415
+Triflumizole 99387-89-0 single chemical entity Component is identical to the substance Triflumizole 99387-89-0 N-[4-chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine Triflumizole C15H15ClF3N3O CCCOCC(=NC1=C(C=C(C=C1)Cl)C(F)(F)F)N2C=CN=C2 InChI=1S/C15H15ClF3N3O/c1-2-7-23-9-14(22-6-5-20-10-22)21-13-4-3-11(16)8-12(13)15(17,18)19/h3-6,8,10H,2,7,9H2,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Hamster (as animal) Chinese 10 Male/Female oral: unspecified 24.0000000000 h no data not applicable Negative RMS: The Netherlands Triflumizole 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumizole 14Dec2009 2009 doi:10.2903/j.efsa.2009.1415
+Triflumizole 99387-89-0 single chemical entity Component is identical to the substance Triflumizole 99387-89-0 N-[4-chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine Triflumizole C15H15ClF3N3O CCCOCC(=NC1=C(C=C(C=C1)Cl)C(F)(F)F)N2C=CN=C2 InChI=1S/C15H15ClF3N3O/c1-2-7-23-9-14(22-6-5-20-10-22)21-13-4-3-11(16)8-12(13)15(17,18)19/h3-6,8,10H,2,7,9H2,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Hamster (as animal) Chinese 10 Male/Female oral: unspecified 12.0000000000 h no data not applicable Negative RMS: The Netherlands Triflumizole 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumizole 14Dec2009 2009 doi:10.2903/j.efsa.2009.1415
+Triflumizole 99387-89-0 single chemical entity Component is identical to the substance Triflumizole 99387-89-0 N-[4-chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine Triflumizole C15H15ClF3N3O CCCOCC(=NC1=C(C=C(C=C1)Cl)C(F)(F)F)N2C=CN=C2 InChI=1S/C15H15ClF3N3O/c1-2-7-23-9-14(22-6-5-20-10-22)21-13-4-3-11(16)8-12(13)15(17,18)19/h3-6,8,10H,2,7,9H2,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Hamster (as animal) Chinese 10 Male/Female oral: unspecified 48.0000000000 h no data not applicable Negative RMS: The Netherlands Triflumizole 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumizole 14Dec2009 2009 doi:10.2903/j.efsa.2009.1415
+Zeta-cypermethrin 257-842-9 52315-07-8 single chemical entity Component is identical to the substance Zeta-Cypermethrin 257-842-9 52315-07-8 (S)-alpha-cyano-3-phenoxybenzyl (1RS,3RS;1RS,3SR)-3-(2,2-dichlorovinyl)-2,2 dimethylcyclopropanecarboxylate Zeta-Cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium Zeta-cypermethrin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Zeta-cypermethrin 257-842-9 52315-07-8 single chemical entity Component is identical to the substance Zeta-Cypermethrin 257-842-9 52315-07-8 (S)-alpha-cyano-3-phenoxybenzyl (1RS,3RS;1RS,3SR)-3-(2,2-dichlorovinyl)-2,2 dimethylcyclopropanecarboxylate Zeta-Cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Belgium Zeta-cypermethrin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Zeta-cypermethrin 257-842-9 52315-07-8 single chemical entity Component is identical to the substance Zeta-Cypermethrin 257-842-9 52315-07-8 (S)-alpha-cyano-3-phenoxybenzyl (1RS,3RS;1RS,3SR)-3-(2,2-dichlorovinyl)-2,2 dimethylcyclopropanecarboxylate Zeta-Cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Belgium Zeta-cypermethrin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Zeta-cypermethrin 257-842-9 52315-07-8 single chemical entity Component is identical to the substance Zeta-Cypermethrin 257-842-9 52315-07-8 (S)-alpha-cyano-3-phenoxybenzyl (1RS,3RS;1RS,3SR)-3-(2,2-dichlorovinyl)-2,2 dimethylcyclopropanecarboxylate Zeta-Cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium Zeta-cypermethrin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Zeta-cypermethrin 257-842-9 52315-07-8 single chemical entity Component is identical to the substance Zeta-Cypermethrin 257-842-9 52315-07-8 (S)-alpha-cyano-3-phenoxybenzyl (1RS,3RS;1RS,3SR)-3-(2,2-dichlorovinyl)-2,2 dimethylcyclopropanecarboxylate Zeta-Cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Positive RMS: Belgium Zeta-cypermethrin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Zeta-cypermethrin 257-842-9 52315-07-8 single chemical entity Component is identical to the substance Zeta-Cypermethrin 257-842-9 52315-07-8 (S)-alpha-cyano-3-phenoxybenzyl (1RS,3RS;1RS,3SR)-3-(2,2-dichlorovinyl)-2,2 dimethylcyclopropanecarboxylate Zeta-Cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium Zeta-cypermethrin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Zeta-cypermethrin 257-842-9 52315-07-8 single chemical entity Component is identical to the substance Zeta-Cypermethrin 257-842-9 52315-07-8 (S)-alpha-cyano-3-phenoxybenzyl (1RS,3RS;1RS,3SR)-3-(2,2-dichlorovinyl)-2,2 dimethylcyclopropanecarboxylate Zeta-Cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Belgium Zeta-cypermethrin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Zeta-cypermethrin 257-842-9 52315-07-8 single chemical entity Component is identical to the substance Zeta-Cypermethrin 257-842-9 52315-07-8 (S)-alpha-cyano-3-phenoxybenzyl (1RS,3RS;1RS,3SR)-3-(2,2-dichlorovinyl)-2,2 dimethylcyclopropanecarboxylate Zeta-Cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium Zeta-cypermethrin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Zeta-cypermethrin 257-842-9 52315-07-8 single chemical entity Component is identical to the substance Zeta-Cypermethrin 257-842-9 52315-07-8 (S)-alpha-cyano-3-phenoxybenzyl (1RS,3RS;1RS,3SR)-3-(2,2-dichlorovinyl)-2,2 dimethylcyclopropanecarboxylate Zeta-Cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Belgium Zeta-cypermethrin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Zeta-cypermethrin 257-842-9 52315-07-8 single chemical entity Component is identical to the substance Zeta-Cypermethrin 257-842-9 52315-07-8 (S)-alpha-cyano-3-phenoxybenzyl (1RS,3RS;1RS,3SR)-3-(2,2-dichlorovinyl)-2,2 dimethylcyclopropanecarboxylate Zeta-Cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium Zeta-cypermethrin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Zeta-cypermethrin 257-842-9 52315-07-8 single chemical entity Component is identical to the substance Zeta-Cypermethrin 257-842-9 52315-07-8 (S)-alpha-cyano-3-phenoxybenzyl (1RS,3RS;1RS,3SR)-3-(2,2-dichlorovinyl)-2,2 dimethylcyclopropanecarboxylate Zeta-Cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Belgium Zeta-cypermethrin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Zeta-cypermethrin 257-842-9 52315-07-8 single chemical entity Component is identical to the substance Zeta-Cypermethrin 257-842-9 52315-07-8 (S)-alpha-cyano-3-phenoxybenzyl (1RS,3RS;1RS,3SR)-3-(2,2-dichlorovinyl)-2,2 dimethylcyclopropanecarboxylate Zeta-Cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m1/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Belgium Zeta-cypermethrin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Zeta-cypermethrin 257-842-9 52315-07-8 single chemical entity Component is identical to the substance Zeta-Cypermethrin 257-842-9 52315-07-8 (S)-alpha-cyano-3-phenoxybenzyl (1RS,3RS;1RS,3SR)-3-(2,2-dichlorovinyl)-2,2 dimethylcyclopropanecarboxylate Zeta-Cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m1/s1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported no data with Negative RMS: Belgium Zeta-cypermethrin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Zeta-cypermethrin 257-842-9 52315-07-8 single chemical entity Component is identical to the substance Zeta-Cypermethrin 257-842-9 52315-07-8 (S)-alpha-cyano-3-phenoxybenzyl (1RS,3RS;1RS,3SR)-3-(2,2-dichlorovinyl)-2,2 dimethylcyclopropanecarboxylate Zeta-Cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m1/s1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported no data without Negative RMS: Belgium Zeta-cypermethrin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Zeta-cypermethrin 257-842-9 52315-07-8 single chemical entity Component is identical to the substance Zeta-Cypermethrin 257-842-9 52315-07-8 (S)-alpha-cyano-3-phenoxybenzyl (1RS,3RS;1RS,3SR)-3-(2,2-dichlorovinyl)-2,2 dimethylcyclopropanecarboxylate Zeta-Cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m1/s1 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Belgium Zeta-cypermethrin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Zeta-cypermethrin 257-842-9 52315-07-8 single chemical entity Component is identical to the substance Zeta-Cypermethrin 257-842-9 52315-07-8 (S)-alpha-cyano-3-phenoxybenzyl (1RS,3RS;1RS,3SR)-3-(2,2-dichlorovinyl)-2,2 dimethylcyclopropanecarboxylate Zeta-Cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m1/s1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Sprague-Dawley 4 Male/Female oral: gavage 6.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Belgium Zeta-cypermethrin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Zeta-cypermethrin 257-842-9 52315-07-8 single chemical entity Component is identical to the substance Zeta-Cypermethrin 257-842-9 52315-07-8 (S)-alpha-cyano-3-phenoxybenzyl (1RS,3RS;1RS,3SR)-3-(2,2-dichlorovinyl)-2,2 dimethylcyclopropanecarboxylate Zeta-Cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m1/s1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Sprague-Dawley 4 Male/Female oral: gavage 18.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Belgium Zeta-cypermethrin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Zeta-cypermethrin 257-842-9 52315-07-8 single chemical entity Component is identical to the substance Zeta-Cypermethrin 257-842-9 52315-07-8 (S)-alpha-cyano-3-phenoxybenzyl (1RS,3RS;1RS,3SR)-3-(2,2-dichlorovinyl)-2,2 dimethylcyclopropanecarboxylate Zeta-Cypermethrin C22H19Cl2NO3 CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m1/s1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Sprague-Dawley 4 Male/Female oral: gavage 30.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Belgium Zeta-cypermethrin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin. 15Jan2009 2009 doi:10.2903/j.efsa.2009.196r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is identical to the substance Trinexapac-ethyl 95266-40-3 Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate Trinexapac-Ethyl C13H16O5 CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1 InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is identical to the substance Trinexapac-ethyl 95266-40-3 Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate Trinexapac-Ethyl C13H16O5 CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1 InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is identical to the substance Trinexapac-ethyl 95266-40-3 Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate Trinexapac-Ethyl C13H16O5 CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1 InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is identical to the substance Trinexapac-ethyl 95266-40-3 Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate Trinexapac-Ethyl C13H16O5 CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1 InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is identical to the substance Trinexapac-ethyl 95266-40-3 Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate Trinexapac-Ethyl C13H16O5 CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1 InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is identical to the substance Trinexapac-ethyl 95266-40-3 Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate Trinexapac-Ethyl C13H16O5 CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1 InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is identical to the substance Trinexapac-ethyl 95266-40-3 Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate Trinexapac-Ethyl C13H16O5 CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1 InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is identical to the substance Trinexapac-ethyl 95266-40-3 Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate Trinexapac-Ethyl C13H16O5 CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1 InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is identical to the substance Trinexapac-ethyl 95266-40-3 Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate Trinexapac-Ethyl C13H16O5 CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1 InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is identical to the substance Trinexapac-ethyl 95266-40-3 Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate Trinexapac-Ethyl C13H16O5 CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1 InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is identical to the substance Trinexapac-ethyl 95266-40-3 Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate Trinexapac-Ethyl C13H16O5 CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1 InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported no data without Negative RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is identical to the substance Trinexapac-ethyl 95266-40-3 Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate Trinexapac-Ethyl C13H16O5 CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1 InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported no data with Negative RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is identical to the substance Trinexapac-ethyl 95266-40-3 Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate Trinexapac-Ethyl C13H16O5 CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1 InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is identical to the substance Trinexapac-ethyl 95266-40-3 Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate Trinexapac-Ethyl C13H16O5 CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1 InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is identical to the substance Trinexapac-ethyl 95266-40-3 Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate Trinexapac-Ethyl C13H16O5 CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1 InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is identical to the substance Trinexapac-ethyl 95266-40-3 Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate Trinexapac-Ethyl C13H16O5 CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1 InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is identical to the substance Trinexapac-ethyl 95266-40-3 Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate Trinexapac-Ethyl C13H16O5 CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1 InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is identical to the substance Trinexapac-ethyl 95266-40-3 Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate Trinexapac-Ethyl C13H16O5 CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1 InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is identical to the substance Trinexapac-ethyl 95266-40-3 Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate Trinexapac-Ethyl C13H16O5 CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1 InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is identical to the substance Trinexapac-ethyl 95266-40-3 Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate Trinexapac-Ethyl C13H16O5 CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1 InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is identical to the substance Trinexapac-ethyl 95266-40-3 Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate Trinexapac-Ethyl C13H16O5 CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1 InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data with Negative RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is identical to the substance Trinexapac-ethyl 95266-40-3 Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate Trinexapac-Ethyl C13H16O5 CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1 InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data without Negative RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is identical to the substance Trinexapac-ethyl 95266-40-3 Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate Trinexapac-Ethyl C13H16O5 CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1 InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data without Negative no information RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is identical to the substance Trinexapac-ethyl 95266-40-3 Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate Trinexapac-Ethyl C13H16O5 CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1 InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data with Negative no information RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is identical to the substance Trinexapac-ethyl 95266-40-3 Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate Trinexapac-Ethyl C13H16O5 CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1 InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported no data with Negative RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is identical to the substance Trinexapac-ethyl 95266-40-3 Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate Trinexapac-Ethyl C13H16O5 CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1 InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported no data without Negative RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is identical to the substance Trinexapac-ethyl 95266-40-3 Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate Trinexapac-Ethyl C13H16O5 CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1 InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported no data without Negative RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is identical to the substance Trinexapac-ethyl 95266-40-3 Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate Trinexapac-Ethyl C13H16O5 CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1 InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Human (as organism) fibroblast Not reported no data without Negative RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is identical to the substance Trinexapac-ethyl 95266-40-3 Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate Trinexapac-Ethyl C13H16O5 CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1 InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Tif:MAGf(SPF) 10 Male/Female oral: unspecified 48.0000000000 h yes not applicable Negative direct evidence-cytotoxicity RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is identical to the substance Trinexapac-ethyl 95266-40-3 Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate Trinexapac-Ethyl C13H16O5 CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1 InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Tif:MAGf(SPF) 10 Male/Female oral: unspecified 16.0000000000 h yes not applicable Negative direct evidence-cytotoxicity RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is identical to the substance Trinexapac-ethyl 95266-40-3 Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate Trinexapac-Ethyl C13H16O5 CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1 InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Tif:MAGf(SPF) 10 Male/Female oral: unspecified 24.0000000000 h yes not applicable Negative direct evidence-cytotoxicity RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is identical to the substance Trinexapac-ethyl 95266-40-3 Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate Trinexapac-Ethyl C13H16O5 CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1 InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Tif:MAGf(SPF) 10 Male/Female oral: unspecified 48.0000000000 h yes not applicable Negative no evidence RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is identical to the substance Trinexapac-ethyl 95266-40-3 Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate Trinexapac-Ethyl C13H16O5 CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1 InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Tif:MAGf(SPF) 10 Male/Female oral: unspecified 24.0000000000 h yes not applicable Negative no evidence RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is identical to the substance Trinexapac-ethyl 95266-40-3 Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate Trinexapac-Ethyl C13H16O5 CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1 InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Tif:MAGf(SPF) 10 Male/Female oral: unspecified 16.0000000000 h yes not applicable Negative no evidence RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is a metabolite of the substance Tricarballylic acid 202-733-3 99-14-9 1,2,3-propanetricarboxylic acid (tricarballylic acid) Not in list C6H8O6 C(C(CC(=O)O)C(=O)O)C(=O)O InChI=1S/C6H8O6/c7-4(8)1-3(6(11)12)2-5(9)10/h3H,1-2H2,(H,7,8)(H,9,10)(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is a metabolite of the substance Tricarballylic acid 202-733-3 99-14-9 1,2,3-propanetricarboxylic acid (tricarballylic acid) Not in list C6H8O6 C(C(CC(=O)O)C(=O)O)C(=O)O InChI=1S/C6H8O6/c7-4(8)1-3(6(11)12)2-5(9)10/h3H,1-2H2,(H,7,8)(H,9,10)(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is a metabolite of the substance Tricarballylic acid 202-733-3 99-14-9 1,2,3-propanetricarboxylic acid (tricarballylic acid) Not in list C6H8O6 C(C(CC(=O)O)C(=O)O)C(=O)O InChI=1S/C6H8O6/c7-4(8)1-3(6(11)12)2-5(9)10/h3H,1-2H2,(H,7,8)(H,9,10)(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is a metabolite of the substance Tricarballylic acid 202-733-3 99-14-9 1,2,3-propanetricarboxylic acid (tricarballylic acid) Not in list C6H8O6 C(C(CC(=O)O)C(=O)O)C(=O)O InChI=1S/C6H8O6/c7-4(8)1-3(6(11)12)2-5(9)10/h3H,1-2H2,(H,7,8)(H,9,10)(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is a metabolite of the substance Tricarballylic acid 202-733-3 99-14-9 1,2,3-propanetricarboxylic acid (tricarballylic acid) Not in list C6H8O6 C(C(CC(=O)O)C(=O)O)C(=O)O InChI=1S/C6H8O6/c7-4(8)1-3(6(11)12)2-5(9)10/h3H,1-2H2,(H,7,8)(H,9,10)(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is a metabolite of the substance Tricarballylic acid 202-733-3 99-14-9 1,2,3-propanetricarboxylic acid (tricarballylic acid) Not in list C6H8O6 C(C(CC(=O)O)C(=O)O)C(=O)O InChI=1S/C6H8O6/c7-4(8)1-3(6(11)12)2-5(9)10/h3H,1-2H2,(H,7,8)(H,9,10)(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported no data with Negative RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is a metabolite of the substance Tricarballylic acid 202-733-3 99-14-9 1,2,3-propanetricarboxylic acid (tricarballylic acid) Not in list C6H8O6 C(C(CC(=O)O)C(=O)O)C(=O)O InChI=1S/C6H8O6/c7-4(8)1-3(6(11)12)2-5(9)10/h3H,1-2H2,(H,7,8)(H,9,10)(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is a metabolite of the substance Tricarballylic acid 202-733-3 99-14-9 1,2,3-propanetricarboxylic acid (tricarballylic acid) Not in list C6H8O6 C(C(CC(=O)O)C(=O)O)C(=O)O InChI=1S/C6H8O6/c7-4(8)1-3(6(11)12)2-5(9)10/h3H,1-2H2,(H,7,8)(H,9,10)(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported no data without Negative RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is a metabolite of the substance Tricarballylic acid 202-733-3 99-14-9 1,2,3-propanetricarboxylic acid (tricarballylic acid) Not in list C6H8O6 C(C(CC(=O)O)C(=O)O)C(=O)O InChI=1S/C6H8O6/c7-4(8)1-3(6(11)12)2-5(9)10/h3H,1-2H2,(H,7,8)(H,9,10)(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is a metabolite of the substance Tricarballylic acid 202-733-3 99-14-9 1,2,3-propanetricarboxylic acid (tricarballylic acid) Not in list C6H8O6 C(C(CC(=O)O)C(=O)O)C(=O)O InChI=1S/C6H8O6/c7-4(8)1-3(6(11)12)2-5(9)10/h3H,1-2H2,(H,7,8)(H,9,10)(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is a metabolite of the substance Tricarballylic acid 202-733-3 99-14-9 1,2,3-propanetricarboxylic acid (tricarballylic acid) Not in list C6H8O6 C(C(CC(=O)O)C(=O)O)C(=O)O InChI=1S/C6H8O6/c7-4(8)1-3(6(11)12)2-5(9)10/h3H,1-2H2,(H,7,8)(H,9,10)(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is a metabolite of the substance Tricarballylic acid 202-733-3 99-14-9 1,2,3-propanetricarboxylic acid (tricarballylic acid) Not in list C6H8O6 C(C(CC(=O)O)C(=O)O)C(=O)O InChI=1S/C6H8O6/c7-4(8)1-3(6(11)12)2-5(9)10/h3H,1-2H2,(H,7,8)(H,9,10)(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is a metabolite of the substance Trinexapac-ethyl metabolite (CGA313458) (2-(4-cyclopropyl-2,4-dioxobutyl)-succinic acid) Trinexapac-ethyl metabolite (CGA313458) C11H14O6 O=C(CC(CC(O)=O)C(O)=O)\C=C(/O)C1CC1 InChI=1/C11H14O6/c12-8(5-9(13)6-1-2-6)3-7(11(16)17)4-10(14)15/h5-7,13H,1-4H2,(H,14,15)(H,16,17)/b9-5- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is a metabolite of the substance Trinexapac-ethyl metabolite (CGA313458) (2-(4-cyclopropyl-2,4-dioxobutyl)-succinic acid) Trinexapac-ethyl metabolite (CGA313458) C11H14O6 O=C(CC(CC(O)=O)C(O)=O)\C=C(/O)C1CC1 InChI=1/C11H14O6/c12-8(5-9(13)6-1-2-6)3-7(11(16)17)4-10(14)15/h5-7,13H,1-4H2,(H,14,15)(H,16,17)/b9-5- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is a metabolite of the substance Trinexapac-ethyl metabolite (CGA313458) (2-(4-cyclopropyl-2,4-dioxobutyl)-succinic acid) Trinexapac-ethyl metabolite (CGA313458) C11H14O6 O=C(CC(CC(O)=O)C(O)=O)\C=C(/O)C1CC1 InChI=1/C11H14O6/c12-8(5-9(13)6-1-2-6)3-7(11(16)17)4-10(14)15/h5-7,13H,1-4H2,(H,14,15)(H,16,17)/b9-5- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is a metabolite of the substance Trinexapac-ethyl metabolite (CGA313458) (2-(4-cyclopropyl-2,4-dioxobutyl)-succinic acid) Trinexapac-ethyl metabolite (CGA313458) C11H14O6 O=C(CC(CC(O)=O)C(O)=O)\C=C(/O)C1CC1 InChI=1/C11H14O6/c12-8(5-9(13)6-1-2-6)3-7(11(16)17)4-10(14)15/h5-7,13H,1-4H2,(H,14,15)(H,16,17)/b9-5- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported no data with Negative RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is a metabolite of the substance Trinexapac-ethyl metabolite (CGA313458) (2-(4-cyclopropyl-2,4-dioxobutyl)-succinic acid) Trinexapac-ethyl metabolite (CGA313458) C11H14O6 O=C(CC(CC(O)=O)C(O)=O)\C=C(/O)C1CC1 InChI=1/C11H14O6/c12-8(5-9(13)6-1-2-6)3-7(11(16)17)4-10(14)15/h5-7,13H,1-4H2,(H,14,15)(H,16,17)/b9-5- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is a metabolite of the substance Trinexapac-ethyl metabolite (CGA313458) (2-(4-cyclopropyl-2,4-dioxobutyl)-succinic acid) Trinexapac-ethyl metabolite (CGA313458) C11H14O6 O=C(CC(CC(O)=O)C(O)=O)\C=C(/O)C1CC1 InChI=1/C11H14O6/c12-8(5-9(13)6-1-2-6)3-7(11(16)17)4-10(14)15/h5-7,13H,1-4H2,(H,14,15)(H,16,17)/b9-5- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is a metabolite of the substance Trinexapac-ethyl metabolite (CGA313458) (2-(4-cyclopropyl-2,4-dioxobutyl)-succinic acid) Trinexapac-ethyl metabolite (CGA313458) C11H14O6 O=C(CC(CC(O)=O)C(O)=O)\C=C(/O)C1CC1 InChI=1/C11H14O6/c12-8(5-9(13)6-1-2-6)3-7(11(16)17)4-10(14)15/h5-7,13H,1-4H2,(H,14,15)(H,16,17)/b9-5- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is a metabolite of the substance Trinexapac-ethyl metabolite (CGA313458) (2-(4-cyclopropyl-2,4-dioxobutyl)-succinic acid) Trinexapac-ethyl metabolite (CGA313458) C11H14O6 O=C(CC(CC(O)=O)C(O)=O)\C=C(/O)C1CC1 InChI=1/C11H14O6/c12-8(5-9(13)6-1-2-6)3-7(11(16)17)4-10(14)15/h5-7,13H,1-4H2,(H,14,15)(H,16,17)/b9-5- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported no data without Negative RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is a metabolite of the substance Trinexapac-ethyl metabolite (CGA313458) (2-(4-cyclopropyl-2,4-dioxobutyl)-succinic acid) Trinexapac-ethyl metabolite (CGA313458) C11H14O6 O=C(CC(CC(O)=O)C(O)=O)\C=C(/O)C1CC1 InChI=1/C11H14O6/c12-8(5-9(13)6-1-2-6)3-7(11(16)17)4-10(14)15/h5-7,13H,1-4H2,(H,14,15)(H,16,17)/b9-5- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is a metabolite of the substance Trinexapac-ethyl metabolite (CGA313458) (2-(4-cyclopropyl-2,4-dioxobutyl)-succinic acid) Trinexapac-ethyl metabolite (CGA313458) C11H14O6 O=C(CC(CC(O)=O)C(O)=O)\C=C(/O)C1CC1 InChI=1/C11H14O6/c12-8(5-9(13)6-1-2-6)3-7(11(16)17)4-10(14)15/h5-7,13H,1-4H2,(H,14,15)(H,16,17)/b9-5- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is a metabolite of the substance Trinexapac-ethyl metabolite (CGA313458) (2-(4-cyclopropyl-2,4-dioxobutyl)-succinic acid) Trinexapac-ethyl metabolite (CGA313458) C11H14O6 O=C(CC(CC(O)=O)C(O)=O)\C=C(/O)C1CC1 InChI=1/C11H14O6/c12-8(5-9(13)6-1-2-6)3-7(11(16)17)4-10(14)15/h5-7,13H,1-4H2,(H,14,15)(H,16,17)/b9-5- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is a metabolite of the substance Trinexapac-ethyl metabolite (CGA313458) (2-(4-cyclopropyl-2,4-dioxobutyl)-succinic acid) Trinexapac-ethyl metabolite (CGA313458) C11H14O6 O=C(CC(CC(O)=O)C(O)=O)\C=C(/O)C1CC1 InChI=1/C11H14O6/c12-8(5-9(13)6-1-2-6)3-7(11(16)17)4-10(14)15/h5-7,13H,1-4H2,(H,14,15)(H,16,17)/b9-5- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is a metabolite of the substance Trinexapac-ethyl metabolite (CGA329773) 4-cyclopropanecarbonyl-3,5-dihydroxybenzoic acid oxo-butyl)-succinic acid Trinexapac-ethyl metabolite (CGA329773) C11H10O5 O=C(c1c(O)cc(cc1O)C(=O)O)C2CC2 InChI=1S/C11H10O5/c12-7-3-6(11(15)16)4-8(13)9(7)10(14)5-1-2-5/h3-5,12-13H,1-2H2,(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is a metabolite of the substance Trinexapac-ethyl metabolite (CGA329773) 4-cyclopropanecarbonyl-3,5-dihydroxybenzoic acid oxo-butyl)-succinic acid Trinexapac-ethyl metabolite (CGA329773) C11H10O5 O=C(c1c(O)cc(cc1O)C(=O)O)C2CC2 InChI=1S/C11H10O5/c12-7-3-6(11(15)16)4-8(13)9(7)10(14)5-1-2-5/h3-5,12-13H,1-2H2,(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported no data with Negative RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is a metabolite of the substance Trinexapac-ethyl metabolite (CGA329773) 4-cyclopropanecarbonyl-3,5-dihydroxybenzoic acid oxo-butyl)-succinic acid Trinexapac-ethyl metabolite (CGA329773) C11H10O5 O=C(c1c(O)cc(cc1O)C(=O)O)C2CC2 InChI=1S/C11H10O5/c12-7-3-6(11(15)16)4-8(13)9(7)10(14)5-1-2-5/h3-5,12-13H,1-2H2,(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is a metabolite of the substance Trinexapac-ethyl metabolite (CGA329773) 4-cyclopropanecarbonyl-3,5-dihydroxybenzoic acid oxo-butyl)-succinic acid Trinexapac-ethyl metabolite (CGA329773) C11H10O5 O=C(c1c(O)cc(cc1O)C(=O)O)C2CC2 InChI=1S/C11H10O5/c12-7-3-6(11(15)16)4-8(13)9(7)10(14)5-1-2-5/h3-5,12-13H,1-2H2,(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is a metabolite of the substance Trinexapac-ethyl metabolite (CGA329773) 4-cyclopropanecarbonyl-3,5-dihydroxybenzoic acid oxo-butyl)-succinic acid Trinexapac-ethyl metabolite (CGA329773) C11H10O5 O=C(c1c(O)cc(cc1O)C(=O)O)C2CC2 InChI=1S/C11H10O5/c12-7-3-6(11(15)16)4-8(13)9(7)10(14)5-1-2-5/h3-5,12-13H,1-2H2,(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is a metabolite of the substance Trinexapac-ethyl metabolite (CGA329773) 4-cyclopropanecarbonyl-3,5-dihydroxybenzoic acid oxo-butyl)-succinic acid Trinexapac-ethyl metabolite (CGA329773) C11H10O5 O=C(c1c(O)cc(cc1O)C(=O)O)C2CC2 InChI=1S/C11H10O5/c12-7-3-6(11(15)16)4-8(13)9(7)10(14)5-1-2-5/h3-5,12-13H,1-2H2,(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported no data without Negative RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is a metabolite of the substance Trinexapac-ethyl metabolite (CGA329773) 4-cyclopropanecarbonyl-3,5-dihydroxybenzoic acid oxo-butyl)-succinic acid Trinexapac-ethyl metabolite (CGA329773) C11H10O5 O=C(c1c(O)cc(cc1O)C(=O)O)C2CC2 InChI=1S/C11H10O5/c12-7-3-6(11(15)16)4-8(13)9(7)10(14)5-1-2-5/h3-5,12-13H,1-2H2,(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is a metabolite of the substance Trinexapac-ethyl metabolite (CGA329773) 4-cyclopropanecarbonyl-3,5-dihydroxybenzoic acid oxo-butyl)-succinic acid Trinexapac-ethyl metabolite (CGA329773) C11H10O5 O=C(c1c(O)cc(cc1O)C(=O)O)C2CC2 InChI=1S/C11H10O5/c12-7-3-6(11(15)16)4-8(13)9(7)10(14)5-1-2-5/h3-5,12-13H,1-2H2,(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is a metabolite of the substance Trinexapac-ethyl metabolite (CGA329773) 4-cyclopropanecarbonyl-3,5-dihydroxybenzoic acid oxo-butyl)-succinic acid Trinexapac-ethyl metabolite (CGA329773) C11H10O5 O=C(c1c(O)cc(cc1O)C(=O)O)C2CC2 InChI=1S/C11H10O5/c12-7-3-6(11(15)16)4-8(13)9(7)10(14)5-1-2-5/h3-5,12-13H,1-2H2,(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is a metabolite of the substance Trinexapac-ethyl metabolite (CGA329773) 4-cyclopropanecarbonyl-3,5-dihydroxybenzoic acid oxo-butyl)-succinic acid Trinexapac-ethyl metabolite (CGA329773) C11H10O5 O=C(c1c(O)cc(cc1O)C(=O)O)C2CC2 InChI=1S/C11H10O5/c12-7-3-6(11(15)16)4-8(13)9(7)10(14)5-1-2-5/h3-5,12-13H,1-2H2,(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is a metabolite of the substance Trinexapac-ethyl metabolite (CGA329773) 4-cyclopropanecarbonyl-3,5-dihydroxybenzoic acid oxo-butyl)-succinic acid Trinexapac-ethyl metabolite (CGA329773) C11H10O5 O=C(c1c(O)cc(cc1O)C(=O)O)C2CC2 InChI=1S/C11H10O5/c12-7-3-6(11(15)16)4-8(13)9(7)10(14)5-1-2-5/h3-5,12-13H,1-2H2,(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is a metabolite of the substance Trinexapac-ethyl metabolite (CGA329773) 4-cyclopropanecarbonyl-3,5-dihydroxybenzoic acid oxo-butyl)-succinic acid Trinexapac-ethyl metabolite (CGA329773) C11H10O5 O=C(c1c(O)cc(cc1O)C(=O)O)C2CC2 InChI=1S/C11H10O5/c12-7-3-6(11(15)16)4-8(13)9(7)10(14)5-1-2-5/h3-5,12-13H,1-2H2,(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is a metabolite of the substance Trinexapac-ethyl metabolite (CGA329773) 4-cyclopropanecarbonyl-3,5-dihydroxybenzoic acid oxo-butyl)-succinic acid Trinexapac-ethyl metabolite (CGA329773) C11H10O5 O=C(c1c(O)cc(cc1O)C(=O)O)C2CC2 InChI=1S/C11H10O5/c12-7-3-6(11(15)16)4-8(13)9(7)10(14)5-1-2-5/h3-5,12-13H,1-2H2,(H,15,16) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data with Negative RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Trinexapac-ethyl 95266-40-3 single chemical entity Component is a metabolite of the substance Trinexapac-ethyl metabolite (CGA329773) 4-cyclopropanecarbonyl-3,5-dihydroxybenzoic acid oxo-butyl)-succinic acid Trinexapac-ethyl metabolite (CGA329773) C11H10O5 O=C(c1c(O)cc(cc1O)C(=O)O)C2CC2 InChI=1S/C11H10O5/c12-7-3-6(11(15)16)4-8(13)9(7)10(14)5-1-2-5/h3-5,12-13H,1-2H2,(H,15,16) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data without Negative RMS: The Netherlands Trinexapac-ethyl 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac 10Jan2006 2006 doi:10.2903/j.efsa.2006.57r
+Triticonazole 131983-72-7 single chemical entity Component is identical to the substance Triticonazole 131983-72-7 5-(4-chlorobenzylidene)-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol Triticonazole C17H20ClN3O OC1(CN2N=CN=C2)C(C)(C)CCC1=CC3=CC=C(Cl)C=C3 InChI=1S/C17H20ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,9,11-12,22H,7-8,10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Austria Triticonazole 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole 18Aug2005 2005 doi:10.2903/j.efsa.2005.33ar
+Triticonazole 131983-72-7 single chemical entity Component is identical to the substance Triticonazole 131983-72-7 5-(4-chlorobenzylidene)-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol Triticonazole C17H20ClN3O OC1(CN2N=CN=C2)C(C)(C)CCC1=CC3=CC=C(Cl)C=C3 InChI=1S/C17H20ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,9,11-12,22H,7-8,10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Austria Triticonazole 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole 18Aug2005 2005 doi:10.2903/j.efsa.2005.33ar
+Triticonazole 131983-72-7 single chemical entity Component is identical to the substance Triticonazole 131983-72-7 5-(4-chlorobenzylidene)-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol Triticonazole C17H20ClN3O OC1(CN2N=CN=C2)C(C)(C)CCC1=CC3=CC=C(Cl)C=C3 InChI=1S/C17H20ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,9,11-12,22H,7-8,10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Austria Triticonazole 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole 18Aug2005 2005 doi:10.2903/j.efsa.2005.33ar
+Triticonazole 131983-72-7 single chemical entity Component is identical to the substance Triticonazole 131983-72-7 5-(4-chlorobenzylidene)-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol Triticonazole C17H20ClN3O OC1(CN2N=CN=C2)C(C)(C)CCC1=CC3=CC=C(Cl)C=C3 InChI=1S/C17H20ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,9,11-12,22H,7-8,10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Austria Triticonazole 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole 18Aug2005 2005 doi:10.2903/j.efsa.2005.33ar
+Triticonazole 131983-72-7 single chemical entity Component is identical to the substance Triticonazole 131983-72-7 5-(4-chlorobenzylidene)-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol Triticonazole C17H20ClN3O OC1(CN2N=CN=C2)C(C)(C)CCC1=CC3=CC=C(Cl)C=C3 InChI=1S/C17H20ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,9,11-12,22H,7-8,10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Austria Triticonazole 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole 18Aug2005 2005 doi:10.2903/j.efsa.2005.33ar
+Triticonazole 131983-72-7 single chemical entity Component is identical to the substance Triticonazole 131983-72-7 5-(4-chlorobenzylidene)-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol Triticonazole C17H20ClN3O OC1(CN2N=CN=C2)C(C)(C)CCC1=CC3=CC=C(Cl)C=C3 InChI=1S/C17H20ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,9,11-12,22H,7-8,10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Austria Triticonazole 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole 18Aug2005 2005 doi:10.2903/j.efsa.2005.33ar
+Triticonazole 131983-72-7 single chemical entity Component is identical to the substance Triticonazole 131983-72-7 5-(4-chlorobenzylidene)-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol Triticonazole C17H20ClN3O OC1(CN2N=CN=C2)C(C)(C)CCC1=CC3=CC=C(Cl)C=C3 InChI=1S/C17H20ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,9,11-12,22H,7-8,10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Austria Triticonazole 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole 18Aug2005 2005 doi:10.2903/j.efsa.2005.33ar
+Triticonazole 131983-72-7 single chemical entity Component is identical to the substance Triticonazole 131983-72-7 5-(4-chlorobenzylidene)-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol Triticonazole C17H20ClN3O OC1(CN2N=CN=C2)C(C)(C)CCC1=CC3=CC=C(Cl)C=C3 InChI=1S/C17H20ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,9,11-12,22H,7-8,10H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Austria Triticonazole 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole 18Aug2005 2005 doi:10.2903/j.efsa.2005.33ar
+Triticonazole 131983-72-7 single chemical entity Component is identical to the substance Triticonazole 131983-72-7 5-(4-chlorobenzylidene)-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol Triticonazole C17H20ClN3O OC1(CN2N=CN=C2)C(C)(C)CCC1=CC3=CC=C(Cl)C=C3 InChI=1S/C17H20ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,9,11-12,22H,7-8,10H2,1-2H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: Austria Triticonazole 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole 18Aug2005 2005 doi:10.2903/j.efsa.2005.33ar
+Triticonazole 131983-72-7 single chemical entity Component is identical to the substance Triticonazole 131983-72-7 5-(4-chlorobenzylidene)-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol Triticonazole C17H20ClN3O OC1(CN2N=CN=C2)C(C)(C)CCC1=CC3=CC=C(Cl)C=C3 InChI=1S/C17H20ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,9,11-12,22H,7-8,10H2,1-2H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: Austria Triticonazole 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole 18Aug2005 2005 doi:10.2903/j.efsa.2005.33ar
+Triticonazole 131983-72-7 single chemical entity Component is identical to the substance Triticonazole 131983-72-7 5-(4-chlorobenzylidene)-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol Triticonazole C17H20ClN3O OC1(CN2N=CN=C2)C(C)(C)CCC1=CC3=CC=C(Cl)C=C3 InChI=1S/C17H20ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,9,11-12,22H,7-8,10H2,1-2H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Austria Triticonazole 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole 18Aug2005 2005 doi:10.2903/j.efsa.2005.33ar
+Triticonazole 131983-72-7 single chemical entity Component is identical to the substance Triticonazole 131983-72-7 5-(4-chlorobenzylidene)-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol Triticonazole C17H20ClN3O OC1(CN2N=CN=C2)C(C)(C)CCC1=CC3=CC=C(Cl)C=C3 InChI=1S/C17H20ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,9,11-12,22H,7-8,10H2,1-2H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Austria Triticonazole 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole 18Aug2005 2005 doi:10.2903/j.efsa.2005.33ar
+Triticonazole 131983-72-7 single chemical entity Component is identical to the substance Triticonazole 131983-72-7 5-(4-chlorobenzylidene)-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol Triticonazole C17H20ClN3O OC1(CN2N=CN=C2)C(C)(C)CCC1=CC3=CC=C(Cl)C=C3 InChI=1S/C17H20ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,9,11-12,22H,7-8,10H2,1-2H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Austria Triticonazole 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole 18Aug2005 2005 doi:10.2903/j.efsa.2005.33ar
+Triticonazole 131983-72-7 single chemical entity Component is identical to the substance Triticonazole 131983-72-7 5-(4-chlorobenzylidene)-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol Triticonazole C17H20ClN3O OC1(CN2N=CN=C2)C(C)(C)CCC1=CC3=CC=C(Cl)C=C3 InChI=1S/C17H20ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,9,11-12,22H,7-8,10H2,1-2H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Austria Triticonazole 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole 18Aug2005 2005 doi:10.2903/j.efsa.2005.33ar
+Triticonazole 131983-72-7 single chemical entity Component is identical to the substance Triticonazole 131983-72-7 5-(4-chlorobenzylidene)-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol Triticonazole C17H20ClN3O OC1(CN2N=CN=C2)C(C)(C)CCC1=CC3=CC=C(Cl)C=C3 InChI=1S/C17H20ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,9,11-12,22H,7-8,10H2,1-2H3 organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Austria Triticonazole 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole 18Aug2005 2005 doi:10.2903/j.efsa.2005.33ar
+Triticonazole 131983-72-7 single chemical entity Component is identical to the substance Triticonazole 131983-72-7 5-(4-chlorobenzylidene)-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol Triticonazole C17H20ClN3O OC1(CN2N=CN=C2)C(C)(C)CCC1=CC3=CC=C(Cl)C=C3 InChI=1S/C17H20ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,9,11-12,22H,7-8,10H2,1-2H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Austria Triticonazole 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole 18Aug2005 2005 doi:10.2903/j.efsa.2005.33ar
+Triticonazole 131983-72-7 single chemical entity Component is identical to the substance Triticonazole 131983-72-7 5-(4-chlorobenzylidene)-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol Triticonazole C17H20ClN3O OC1(CN2N=CN=C2)C(C)(C)CCC1=CC3=CC=C(Cl)C=C3 InChI=1S/C17H20ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,9,11-12,22H,7-8,10H2,1-2H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Austria Triticonazole 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole 18Aug2005 2005 doi:10.2903/j.efsa.2005.33ar
+Triticonazole 131983-72-7 single chemical entity Component is identical to the substance Triticonazole 131983-72-7 5-(4-chlorobenzylidene)-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol Triticonazole C17H20ClN3O OC1(CN2N=CN=C2)C(C)(C)CCC1=CC3=CC=C(Cl)C=C3 InChI=1S/C17H20ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,9,11-12,22H,7-8,10H2,1-2H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 72.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Austria Triticonazole 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole 18Aug2005 2005 doi:10.2903/j.efsa.2005.33ar
+Triticonazole 131983-72-7 single chemical entity Component is a metabolite of the substance Triticonazole metabolite RPA406341 [(E)-2-(4-chlorobenzylidene)-5,5-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopen-tan-1,3-trans-diol] Not in list C18H22ClN3O2 O[C@H](Cn1cncn1)C3\C(=C\c2ccc(Cl)cc2)[C@H](O)C[C@]3(C)C InChI=1/C18H22ClN3O2/c1-18(2)8-15(23)14(7-12-3-5-13(19)6-4-12)17(18)16(24)9-22-11-20-10-21-22/h3-7,10-11,15-17,23-24H,8-9H2,1-2H3/b14-7+/t15-,16-,17?/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Austria Triticonazole 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole 18Aug2005 2005 doi:10.2903/j.efsa.2005.33ar
+Triticonazole 131983-72-7 single chemical entity Component is a metabolite of the substance Triticonazole metabolite RPA406341 [(E)-2-(4-chlorobenzylidene)-5,5-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopen-tan-1,3-trans-diol] Not in list C18H22ClN3O2 O[C@H](Cn1cncn1)C3\C(=C\c2ccc(Cl)cc2)[C@H](O)C[C@]3(C)C InChI=1/C18H22ClN3O2/c1-18(2)8-15(23)14(7-12-3-5-13(19)6-4-12)17(18)16(24)9-22-11-20-10-21-22/h3-7,10-11,15-17,23-24H,8-9H2,1-2H3/b14-7+/t15-,16-,17?/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Austria Triticonazole 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole 18Aug2005 2005 doi:10.2903/j.efsa.2005.33ar
+Triticonazole 131983-72-7 single chemical entity Component is a metabolite of the substance Triticonazole metabolite RPA406341 [(E)-2-(4-chlorobenzylidene)-5,5-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopen-tan-1,3-trans-diol] Not in list C18H22ClN3O2 O[C@H](Cn1cncn1)C3\C(=C\c2ccc(Cl)cc2)[C@H](O)C[C@]3(C)C InChI=1/C18H22ClN3O2/c1-18(2)8-15(23)14(7-12-3-5-13(19)6-4-12)17(18)16(24)9-22-11-20-10-21-22/h3-7,10-11,15-17,23-24H,8-9H2,1-2H3/b14-7+/t15-,16-,17?/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Austria Triticonazole 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole 18Aug2005 2005 doi:10.2903/j.efsa.2005.33ar
+Triticonazole 131983-72-7 single chemical entity Component is a metabolite of the substance Triticonazole metabolite RPA406341 [(E)-2-(4-chlorobenzylidene)-5,5-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopen-tan-1,3-trans-diol] Not in list C18H22ClN3O2 O[C@H](Cn1cncn1)C3\C(=C\c2ccc(Cl)cc2)[C@H](O)C[C@]3(C)C InChI=1/C18H22ClN3O2/c1-18(2)8-15(23)14(7-12-3-5-13(19)6-4-12)17(18)16(24)9-22-11-20-10-21-22/h3-7,10-11,15-17,23-24H,8-9H2,1-2H3/b14-7+/t15-,16-,17?/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Austria Triticonazole 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole 18Aug2005 2005 doi:10.2903/j.efsa.2005.33ar
+Triticonazole 131983-72-7 single chemical entity Component is a metabolite of the substance Triticonazole metabolite RPA406341 [(E)-2-(4-chlorobenzylidene)-5,5-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopen-tan-1,3-trans-diol] Not in list C18H22ClN3O2 O[C@H](Cn1cncn1)C3\C(=C\c2ccc(Cl)cc2)[C@H](O)C[C@]3(C)C InChI=1/C18H22ClN3O2/c1-18(2)8-15(23)14(7-12-3-5-13(19)6-4-12)17(18)16(24)9-22-11-20-10-21-22/h3-7,10-11,15-17,23-24H,8-9H2,1-2H3/b14-7+/t15-,16-,17?/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Austria Triticonazole 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole 18Aug2005 2005 doi:10.2903/j.efsa.2005.33ar
+Triticonazole 131983-72-7 single chemical entity Component is a metabolite of the substance Triticonazole metabolite RPA406341 [(E)-2-(4-chlorobenzylidene)-5,5-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopen-tan-1,3-trans-diol] Not in list C18H22ClN3O2 O[C@H](Cn1cncn1)C3\C(=C\c2ccc(Cl)cc2)[C@H](O)C[C@]3(C)C InChI=1/C18H22ClN3O2/c1-18(2)8-15(23)14(7-12-3-5-13(19)6-4-12)17(18)16(24)9-22-11-20-10-21-22/h3-7,10-11,15-17,23-24H,8-9H2,1-2H3/b14-7+/t15-,16-,17?/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Austria Triticonazole 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole 18Aug2005 2005 doi:10.2903/j.efsa.2005.33ar
+Triticonazole 131983-72-7 single chemical entity Component is a metabolite of the substance Triticonazole metabolite RPA406341 [(E)-2-(4-chlorobenzylidene)-5,5-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopen-tan-1,3-trans-diol] Not in list C18H22ClN3O2 O[C@H](Cn1cncn1)C3\C(=C\c2ccc(Cl)cc2)[C@H](O)C[C@]3(C)C InChI=1/C18H22ClN3O2/c1-18(2)8-15(23)14(7-12-3-5-13(19)6-4-12)17(18)16(24)9-22-11-20-10-21-22/h3-7,10-11,15-17,23-24H,8-9H2,1-2H3/b14-7+/t15-,16-,17?/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Austria Triticonazole 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole 18Aug2005 2005 doi:10.2903/j.efsa.2005.33ar
+Triticonazole 131983-72-7 single chemical entity Component is a metabolite of the substance Triticonazole metabolite RPA406341 [(E)-2-(4-chlorobenzylidene)-5,5-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopen-tan-1,3-trans-diol] Not in list C18H22ClN3O2 O[C@H](Cn1cncn1)C3\C(=C\c2ccc(Cl)cc2)[C@H](O)C[C@]3(C)C InChI=1/C18H22ClN3O2/c1-18(2)8-15(23)14(7-12-3-5-13(19)6-4-12)17(18)16(24)9-22-11-20-10-21-22/h3-7,10-11,15-17,23-24H,8-9H2,1-2H3/b14-7+/t15-,16-,17?/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Austria Triticonazole 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole 18Aug2005 2005 doi:10.2903/j.efsa.2005.33ar
+Triticonazole 131983-72-7 single chemical entity Component is a metabolite of the substance Triticonazole metabolite RPA406341 [(E)-2-(4-chlorobenzylidene)-5,5-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopen-tan-1,3-trans-diol] Not in list C18H22ClN3O2 O[C@H](Cn1cncn1)C3\C(=C\c2ccc(Cl)cc2)[C@H](O)C[C@]3(C)C InChI=1/C18H22ClN3O2/c1-18(2)8-15(23)14(7-12-3-5-13(19)6-4-12)17(18)16(24)9-22-11-20-10-21-22/h3-7,10-11,15-17,23-24H,8-9H2,1-2H3/b14-7+/t15-,16-,17?/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Austria Triticonazole 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole 18Aug2005 2005 doi:10.2903/j.efsa.2005.33ar
+Triticonazole 131983-72-7 single chemical entity Component is a metabolite of the substance Triticonazole metabolite RPA406341 [(E)-2-(4-chlorobenzylidene)-5,5-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopen-tan-1,3-trans-diol] Not in list C18H22ClN3O2 O[C@H](Cn1cncn1)C3\C(=C\c2ccc(Cl)cc2)[C@H](O)C[C@]3(C)C InChI=1/C18H22ClN3O2/c1-18(2)8-15(23)14(7-12-3-5-13(19)6-4-12)17(18)16(24)9-22-11-20-10-21-22/h3-7,10-11,15-17,23-24H,8-9H2,1-2H3/b14-7+/t15-,16-,17?/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Austria Triticonazole 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole 18Aug2005 2005 doi:10.2903/j.efsa.2005.33ar
+Triticonazole 131983-72-7 single chemical entity Component is a metabolite of the substance Triticonazole metabolite RPA406203 (5E)-5-[(4-chlorophenyl)methylidene]-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol Not in list C17H20ClN3O Clc1ccc(cc1)\C=C3/CCC(C)(C)C3(O)Cn2cncn2 InChI=1/C17H20ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,9,11-12,22H,7-8,10H2,1-2H3/b14-9+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Austria Triticonazole 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole 18Aug2005 2005 doi:10.2903/j.efsa.2005.33ar
+Triticonazole 131983-72-7 single chemical entity Component is a metabolite of the substance Triticonazole metabolite RPA406203 (5E)-5-[(4-chlorophenyl)methylidene]-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol Not in list C17H20ClN3O Clc1ccc(cc1)\C=C3/CCC(C)(C)C3(O)Cn2cncn2 InChI=1/C17H20ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,9,11-12,22H,7-8,10H2,1-2H3/b14-9+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Austria Triticonazole 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole 18Aug2005 2005 doi:10.2903/j.efsa.2005.33ar
+Triticonazole 131983-72-7 single chemical entity Component is a metabolite of the substance Triticonazole metabolite RPA406203 (5E)-5-[(4-chlorophenyl)methylidene]-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol Not in list C17H20ClN3O Clc1ccc(cc1)\C=C3/CCC(C)(C)C3(O)Cn2cncn2 InChI=1/C17H20ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,9,11-12,22H,7-8,10H2,1-2H3/b14-9+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Austria Triticonazole 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole 18Aug2005 2005 doi:10.2903/j.efsa.2005.33ar
+Triticonazole 131983-72-7 single chemical entity Component is a metabolite of the substance Triticonazole metabolite RPA406203 (5E)-5-[(4-chlorophenyl)methylidene]-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol Not in list C17H20ClN3O Clc1ccc(cc1)\C=C3/CCC(C)(C)C3(O)Cn2cncn2 InChI=1/C17H20ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,9,11-12,22H,7-8,10H2,1-2H3/b14-9+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Austria Triticonazole 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole 18Aug2005 2005 doi:10.2903/j.efsa.2005.33ar
+Triticonazole 131983-72-7 single chemical entity Component is a metabolite of the substance Triticonazole metabolite RPA406203 (5E)-5-[(4-chlorophenyl)methylidene]-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol Not in list C17H20ClN3O Clc1ccc(cc1)\C=C3/CCC(C)(C)C3(O)Cn2cncn2 InChI=1/C17H20ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,9,11-12,22H,7-8,10H2,1-2H3/b14-9+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Austria Triticonazole 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole 18Aug2005 2005 doi:10.2903/j.efsa.2005.33ar
+Triticonazole 131983-72-7 single chemical entity Component is a metabolite of the substance Triticonazole metabolite RPA406203 (5E)-5-[(4-chlorophenyl)methylidene]-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol Not in list C17H20ClN3O Clc1ccc(cc1)\C=C3/CCC(C)(C)C3(O)Cn2cncn2 InChI=1/C17H20ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,9,11-12,22H,7-8,10H2,1-2H3/b14-9+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Austria Triticonazole 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole 18Aug2005 2005 doi:10.2903/j.efsa.2005.33ar
+Triticonazole 131983-72-7 single chemical entity Component is a metabolite of the substance Triticonazole metabolite RPA406203 (5E)-5-[(4-chlorophenyl)methylidene]-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol Not in list C17H20ClN3O Clc1ccc(cc1)\C=C3/CCC(C)(C)C3(O)Cn2cncn2 InChI=1/C17H20ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,9,11-12,22H,7-8,10H2,1-2H3/b14-9+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Austria Triticonazole 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole 18Aug2005 2005 doi:10.2903/j.efsa.2005.33ar
+Triticonazole 131983-72-7 single chemical entity Component is a metabolite of the substance Triticonazole metabolite RPA406203 (5E)-5-[(4-chlorophenyl)methylidene]-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol Not in list C17H20ClN3O Clc1ccc(cc1)\C=C3/CCC(C)(C)C3(O)Cn2cncn2 InChI=1/C17H20ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,9,11-12,22H,7-8,10H2,1-2H3/b14-9+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Austria Triticonazole 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole 18Aug2005 2005 doi:10.2903/j.efsa.2005.33ar
+Triticonazole 131983-72-7 single chemical entity Component is a metabolite of the substance Triticonazole metabolite RPA406203 (5E)-5-[(4-chlorophenyl)methylidene]-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol Not in list C17H20ClN3O Clc1ccc(cc1)\C=C3/CCC(C)(C)C3(O)Cn2cncn2 InChI=1/C17H20ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,9,11-12,22H,7-8,10H2,1-2H3/b14-9+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Austria Triticonazole 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole 18Aug2005 2005 doi:10.2903/j.efsa.2005.33ar
+Triticonazole 131983-72-7 single chemical entity Component is a metabolite of the substance Triticonazole metabolite RPA406203 (5E)-5-[(4-chlorophenyl)methylidene]-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol Not in list C17H20ClN3O Clc1ccc(cc1)\C=C3/CCC(C)(C)C3(O)Cn2cncn2 InChI=1/C17H20ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,9,11-12,22H,7-8,10H2,1-2H3/b14-9+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Austria Triticonazole 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole 18Aug2005 2005 doi:10.2903/j.efsa.2005.33ar
+Valiphenal 283159-90-0 single chemical entity Component is identical to the substance Valiphenal 283159-90-0 Methyl 3-(4-chlorophenyl)-3-[[(2S)-3-methyl-2-(propan-2-yloxycarbonylamino) butanoyl]amino]propanoate Valifenalate C19H27ClN2O5 CC(C)[C@@H](C(=O)NC(CC(=O)OC)C1=CC=C(C=C1)Cl)NC(=O)OC(C)C InChI=1S/C19H27ClN2O5/c1-11(2)17(22-19(25)27-12(3)4)18(24)21-15(10-16(23)26-5)13-6-8-14(20)9-7-13/h6-9,11-12,15,17H,10H2,1-5H3,(H,21,24)(H,22,25)/t15?,17-/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Hungary Valifenalate (Formerly Valiphenal) (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate. 20Jun2013 2013 doi:10.2903/j.efsa.2013.3253
+Valiphenal 283159-90-0 single chemical entity Component is identical to the substance Valiphenal 283159-90-0 Methyl 3-(4-chlorophenyl)-3-[[(2S)-3-methyl-2-(propan-2-yloxycarbonylamino) butanoyl]amino]propanoate Valifenalate C19H27ClN2O5 CC(C)[C@@H](C(=O)NC(CC(=O)OC)C1=CC=C(C=C1)Cl)NC(=O)OC(C)C InChI=1S/C19H27ClN2O5/c1-11(2)17(22-19(25)27-12(3)4)18(24)21-15(10-16(23)26-5)13-6-8-14(20)9-7-13/h6-9,11-12,15,17H,10H2,1-5H3,(H,21,24)(H,22,25)/t15?,17-/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Hungary Valifenalate (Formerly Valiphenal) (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate. 20Jun2013 2013 doi:10.2903/j.efsa.2013.3253
+Valiphenal 283159-90-0 single chemical entity Component is identical to the substance Valiphenal 283159-90-0 Methyl 3-(4-chlorophenyl)-3-[[(2S)-3-methyl-2-(propan-2-yloxycarbonylamino) butanoyl]amino]propanoate Valifenalate C19H27ClN2O5 CC(C)[C@@H](C(=O)NC(CC(=O)OC)C1=CC=C(C=C1)Cl)NC(=O)OC(C)C InChI=1S/C19H27ClN2O5/c1-11(2)17(22-19(25)27-12(3)4)18(24)21-15(10-16(23)26-5)13-6-8-14(20)9-7-13/h6-9,11-12,15,17H,10H2,1-5H3,(H,21,24)(H,22,25)/t15?,17-/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Hungary Valifenalate (Formerly Valiphenal) (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate. 20Jun2013 2013 doi:10.2903/j.efsa.2013.3253
+Valiphenal 283159-90-0 single chemical entity Component is identical to the substance Valiphenal 283159-90-0 Methyl 3-(4-chlorophenyl)-3-[[(2S)-3-methyl-2-(propan-2-yloxycarbonylamino) butanoyl]amino]propanoate Valifenalate C19H27ClN2O5 CC(C)[C@@H](C(=O)NC(CC(=O)OC)C1=CC=C(C=C1)Cl)NC(=O)OC(C)C InChI=1S/C19H27ClN2O5/c1-11(2)17(22-19(25)27-12(3)4)18(24)21-15(10-16(23)26-5)13-6-8-14(20)9-7-13/h6-9,11-12,15,17H,10H2,1-5H3,(H,21,24)(H,22,25)/t15?,17-/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Hungary Valifenalate (Formerly Valiphenal) (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate. 20Jun2013 2013 doi:10.2903/j.efsa.2013.3253
+Valiphenal 283159-90-0 single chemical entity Component is identical to the substance Valiphenal 283159-90-0 Methyl 3-(4-chlorophenyl)-3-[[(2S)-3-methyl-2-(propan-2-yloxycarbonylamino) butanoyl]amino]propanoate Valifenalate C19H27ClN2O5 CC(C)[C@@H](C(=O)NC(CC(=O)OC)C1=CC=C(C=C1)Cl)NC(=O)OC(C)C InChI=1S/C19H27ClN2O5/c1-11(2)17(22-19(25)27-12(3)4)18(24)21-15(10-16(23)26-5)13-6-8-14(20)9-7-13/h6-9,11-12,15,17H,10H2,1-5H3,(H,21,24)(H,22,25)/t15?,17-/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Hungary Valifenalate (Formerly Valiphenal) (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate. 20Jun2013 2013 doi:10.2903/j.efsa.2013.3253
+Valiphenal 283159-90-0 single chemical entity Component is identical to the substance Valiphenal 283159-90-0 Methyl 3-(4-chlorophenyl)-3-[[(2S)-3-methyl-2-(propan-2-yloxycarbonylamino) butanoyl]amino]propanoate Valifenalate C19H27ClN2O5 CC(C)[C@@H](C(=O)NC(CC(=O)OC)C1=CC=C(C=C1)Cl)NC(=O)OC(C)C InChI=1S/C19H27ClN2O5/c1-11(2)17(22-19(25)27-12(3)4)18(24)21-15(10-16(23)26-5)13-6-8-14(20)9-7-13/h6-9,11-12,15,17H,10H2,1-5H3,(H,21,24)(H,22,25)/t15?,17-/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Hungary Valifenalate (Formerly Valiphenal) (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate. 20Jun2013 2013 doi:10.2903/j.efsa.2013.3253
+Valiphenal 283159-90-0 single chemical entity Component is identical to the substance Valiphenal 283159-90-0 Methyl 3-(4-chlorophenyl)-3-[[(2S)-3-methyl-2-(propan-2-yloxycarbonylamino) butanoyl]amino]propanoate Valifenalate C19H27ClN2O5 CC(C)[C@@H](C(=O)NC(CC(=O)OC)C1=CC=C(C=C1)Cl)NC(=O)OC(C)C InChI=1S/C19H27ClN2O5/c1-11(2)17(22-19(25)27-12(3)4)18(24)21-15(10-16(23)26-5)13-6-8-14(20)9-7-13/h6-9,11-12,15,17H,10H2,1-5H3,(H,21,24)(H,22,25)/t15?,17-/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Hungary Valifenalate (Formerly Valiphenal) (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate. 20Jun2013 2013 doi:10.2903/j.efsa.2013.3253
+Valiphenal 283159-90-0 single chemical entity Component is identical to the substance Valiphenal 283159-90-0 Methyl 3-(4-chlorophenyl)-3-[[(2S)-3-methyl-2-(propan-2-yloxycarbonylamino) butanoyl]amino]propanoate Valifenalate C19H27ClN2O5 CC(C)[C@@H](C(=O)NC(CC(=O)OC)C1=CC=C(C=C1)Cl)NC(=O)OC(C)C InChI=1S/C19H27ClN2O5/c1-11(2)17(22-19(25)27-12(3)4)18(24)21-15(10-16(23)26-5)13-6-8-14(20)9-7-13/h6-9,11-12,15,17H,10H2,1-5H3,(H,21,24)(H,22,25)/t15?,17-/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Hungary Valifenalate (Formerly Valiphenal) (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate. 20Jun2013 2013 doi:10.2903/j.efsa.2013.3253
+Valiphenal 283159-90-0 single chemical entity Component is identical to the substance Valiphenal 283159-90-0 Methyl 3-(4-chlorophenyl)-3-[[(2S)-3-methyl-2-(propan-2-yloxycarbonylamino) butanoyl]amino]propanoate Valifenalate C19H27ClN2O5 CC(C)[C@@H](C(=O)NC(CC(=O)OC)C1=CC=C(C=C1)Cl)NC(=O)OC(C)C InChI=1S/C19H27ClN2O5/c1-11(2)17(22-19(25)27-12(3)4)18(24)21-15(10-16(23)26-5)13-6-8-14(20)9-7-13/h6-9,11-12,15,17H,10H2,1-5H3,(H,21,24)(H,22,25)/t15?,17-/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Hungary Valifenalate (Formerly Valiphenal) (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate. 20Jun2013 2013 doi:10.2903/j.efsa.2013.3253
+Valiphenal 283159-90-0 single chemical entity Component is identical to the substance Valiphenal 283159-90-0 Methyl 3-(4-chlorophenyl)-3-[[(2S)-3-methyl-2-(propan-2-yloxycarbonylamino) butanoyl]amino]propanoate Valifenalate C19H27ClN2O5 CC(C)[C@@H](C(=O)NC(CC(=O)OC)C1=CC=C(C=C1)Cl)NC(=O)OC(C)C InChI=1S/C19H27ClN2O5/c1-11(2)17(22-19(25)27-12(3)4)18(24)21-15(10-16(23)26-5)13-6-8-14(20)9-7-13/h6-9,11-12,15,17H,10H2,1-5H3,(H,21,24)(H,22,25)/t15?,17-/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Hungary Valifenalate (Formerly Valiphenal) (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate. 20Jun2013 2013 doi:10.2903/j.efsa.2013.3253
+Valiphenal 283159-90-0 single chemical entity Component is identical to the substance Valiphenal 283159-90-0 Methyl 3-(4-chlorophenyl)-3-[[(2S)-3-methyl-2-(propan-2-yloxycarbonylamino) butanoyl]amino]propanoate Valifenalate C19H27ClN2O5 CC(C)[C@@H](C(=O)NC(CC(=O)OC)C1=CC=C(C=C1)Cl)NC(=O)OC(C)C InChI=1S/C19H27ClN2O5/c1-11(2)17(22-19(25)27-12(3)4)18(24)21-15(10-16(23)26-5)13-6-8-14(20)9-7-13/h6-9,11-12,15,17H,10H2,1-5H3,(H,21,24)(H,22,25)/t15?,17-/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: Hungary Valifenalate (Formerly Valiphenal) (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate. 20Jun2013 2013 doi:10.2903/j.efsa.2013.3253
+Valiphenal 283159-90-0 single chemical entity Component is identical to the substance Valiphenal 283159-90-0 Methyl 3-(4-chlorophenyl)-3-[[(2S)-3-methyl-2-(propan-2-yloxycarbonylamino) butanoyl]amino]propanoate Valifenalate C19H27ClN2O5 CC(C)[C@@H](C(=O)NC(CC(=O)OC)C1=CC=C(C=C1)Cl)NC(=O)OC(C)C InChI=1S/C19H27ClN2O5/c1-11(2)17(22-19(25)27-12(3)4)18(24)21-15(10-16(23)26-5)13-6-8-14(20)9-7-13/h6-9,11-12,15,17H,10H2,1-5H3,(H,21,24)(H,22,25)/t15?,17-/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: Hungary Valifenalate (Formerly Valiphenal) (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate. 20Jun2013 2013 doi:10.2903/j.efsa.2013.3253
+Valiphenal 283159-90-0 single chemical entity Component is identical to the substance Valiphenal 283159-90-0 Methyl 3-(4-chlorophenyl)-3-[[(2S)-3-methyl-2-(propan-2-yloxycarbonylamino) butanoyl]amino]propanoate Valifenalate C19H27ClN2O5 CC(C)[C@@H](C(=O)NC(CC(=O)OC)C1=CC=C(C=C1)Cl)NC(=O)OC(C)C InChI=1S/C19H27ClN2O5/c1-11(2)17(22-19(25)27-12(3)4)18(24)21-15(10-16(23)26-5)13-6-8-14(20)9-7-13/h6-9,11-12,15,17H,10H2,1-5H3,(H,21,24)(H,22,25)/t15?,17-/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Hungary Valifenalate (Formerly Valiphenal) (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate. 20Jun2013 2013 doi:10.2903/j.efsa.2013.3253
+Valiphenal 283159-90-0 single chemical entity Component is identical to the substance Valiphenal 283159-90-0 Methyl 3-(4-chlorophenyl)-3-[[(2S)-3-methyl-2-(propan-2-yloxycarbonylamino) butanoyl]amino]propanoate Valifenalate C19H27ClN2O5 CC(C)[C@@H](C(=O)NC(CC(=O)OC)C1=CC=C(C=C1)Cl)NC(=O)OC(C)C InChI=1S/C19H27ClN2O5/c1-11(2)17(22-19(25)27-12(3)4)18(24)21-15(10-16(23)26-5)13-6-8-14(20)9-7-13/h6-9,11-12,15,17H,10H2,1-5H3,(H,21,24)(H,22,25)/t15?,17-/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Hungary Valifenalate (Formerly Valiphenal) (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate. 20Jun2013 2013 doi:10.2903/j.efsa.2013.3253
+Valiphenal 283159-90-0 single chemical entity Component is identical to the substance Valiphenal 283159-90-0 Methyl 3-(4-chlorophenyl)-3-[[(2S)-3-methyl-2-(propan-2-yloxycarbonylamino) butanoyl]amino]propanoate Valifenalate C19H27ClN2O5 CC(C)[C@@H](C(=O)NC(CC(=O)OC)C1=CC=C(C=C1)Cl)NC(=O)OC(C)C InChI=1S/C19H27ClN2O5/c1-11(2)17(22-19(25)27-12(3)4)18(24)21-15(10-16(23)26-5)13-6-8-14(20)9-7-13/h6-9,11-12,15,17H,10H2,1-5H3,(H,21,24)(H,22,25)/t15?,17-/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 11 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Hungary Valifenalate (Formerly Valiphenal) (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate. 20Jun2013 2013 doi:10.2903/j.efsa.2013.3253
+Valiphenal 283159-90-0 single chemical entity Component is identical to the substance Valiphenal 283159-90-0 Methyl 3-(4-chlorophenyl)-3-[[(2S)-3-methyl-2-(propan-2-yloxycarbonylamino) butanoyl]amino]propanoate Valifenalate C19H27ClN2O5 CC(C)[C@@H](C(=O)NC(CC(=O)OC)C1=CC=C(C=C1)Cl)NC(=O)OC(C)C InChI=1S/C19H27ClN2O5/c1-11(2)17(22-19(25)27-12(3)4)18(24)21-15(10-16(23)26-5)13-6-8-14(20)9-7-13/h6-9,11-12,15,17H,10H2,1-5H3,(H,21,24)(H,22,25)/t15?,17-/m0/s1 organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 11 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Hungary Valifenalate (Formerly Valiphenal) (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate. 20Jun2013 2013 doi:10.2903/j.efsa.2013.3253
+Valiphenal 283159-90-0 single chemical entity Component is a metabolite of the substance (3RS)-3-(4-chlorophenyl)-3-{[N-(isopropoxycarbonyl)-L-valyl]amino}propanoic acid (3RS)-3-(4-chlorophenyl)-3-{[N-(isopropoxycarbonyl)-L-valyl]amino}propanoic acid Not in list C18H25ClN2O5 Clc1ccc(cc1)C(NC(=O)[C@@H](NC(=O)OC(C)C)C(C)C)CC(O)=O InChI=1/C18H25ClN2O5/c1-10(2)16(21-18(25)26-11(3)4)17(24)20-14(9-15(22)23)12-5-7-13(19)8-6-12/h5-8,10-11,14,16H,9H2,1-4H3,(H,20,24)(H,21,25)(H,22,23)/t14?,16-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Hungary Valifenalate (Formerly Valiphenal) (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate. 20Jun2013 2013 doi:10.2903/j.efsa.2013.3253
+Valiphenal 283159-90-0 single chemical entity Component is a metabolite of the substance (3RS)-3-(4-chlorophenyl)-3-{[N-(isopropoxycarbonyl)-L-valyl]amino}propanoic acid (3RS)-3-(4-chlorophenyl)-3-{[N-(isopropoxycarbonyl)-L-valyl]amino}propanoic acid Not in list C18H25ClN2O5 Clc1ccc(cc1)C(NC(=O)[C@@H](NC(=O)OC(C)C)C(C)C)CC(O)=O InChI=1/C18H25ClN2O5/c1-10(2)16(21-18(25)26-11(3)4)17(24)20-14(9-15(22)23)12-5-7-13(19)8-6-12/h5-8,10-11,14,16H,9H2,1-4H3,(H,20,24)(H,21,25)(H,22,23)/t14?,16-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Hungary Valifenalate (Formerly Valiphenal) (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate. 20Jun2013 2013 doi:10.2903/j.efsa.2013.3253
+Valiphenal 283159-90-0 single chemical entity Component is a metabolite of the substance (3RS)-3-(4-chlorophenyl)-3-{[N-(isopropoxycarbonyl)-L-valyl]amino}propanoic acid (3RS)-3-(4-chlorophenyl)-3-{[N-(isopropoxycarbonyl)-L-valyl]amino}propanoic acid Not in list C18H25ClN2O5 Clc1ccc(cc1)C(NC(=O)[C@@H](NC(=O)OC(C)C)C(C)C)CC(O)=O InChI=1/C18H25ClN2O5/c1-10(2)16(21-18(25)26-11(3)4)17(24)20-14(9-15(22)23)12-5-7-13(19)8-6-12/h5-8,10-11,14,16H,9H2,1-4H3,(H,20,24)(H,21,25)(H,22,23)/t14?,16-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Hungary Valifenalate (Formerly Valiphenal) (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate. 20Jun2013 2013 doi:10.2903/j.efsa.2013.3253
+Valiphenal 283159-90-0 single chemical entity Component is a metabolite of the substance (3RS)-3-(4-chlorophenyl)-3-{[N-(isopropoxycarbonyl)-L-valyl]amino}propanoic acid (3RS)-3-(4-chlorophenyl)-3-{[N-(isopropoxycarbonyl)-L-valyl]amino}propanoic acid Not in list C18H25ClN2O5 Clc1ccc(cc1)C(NC(=O)[C@@H](NC(=O)OC(C)C)C(C)C)CC(O)=O InChI=1/C18H25ClN2O5/c1-10(2)16(21-18(25)26-11(3)4)17(24)20-14(9-15(22)23)12-5-7-13(19)8-6-12/h5-8,10-11,14,16H,9H2,1-4H3,(H,20,24)(H,21,25)(H,22,23)/t14?,16-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Hungary Valifenalate (Formerly Valiphenal) (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate. 20Jun2013 2013 doi:10.2903/j.efsa.2013.3253
+Valiphenal 283159-90-0 single chemical entity Component is a metabolite of the substance (3RS)-3-(4-chlorophenyl)-3-{[N-(isopropoxycarbonyl)-L-valyl]amino}propanoic acid (3RS)-3-(4-chlorophenyl)-3-{[N-(isopropoxycarbonyl)-L-valyl]amino}propanoic acid Not in list C18H25ClN2O5 Clc1ccc(cc1)C(NC(=O)[C@@H](NC(=O)OC(C)C)C(C)C)CC(O)=O InChI=1/C18H25ClN2O5/c1-10(2)16(21-18(25)26-11(3)4)17(24)20-14(9-15(22)23)12-5-7-13(19)8-6-12/h5-8,10-11,14,16H,9H2,1-4H3,(H,20,24)(H,21,25)(H,22,23)/t14?,16-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Hungary Valifenalate (Formerly Valiphenal) (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate. 20Jun2013 2013 doi:10.2903/j.efsa.2013.3253
+Valiphenal 283159-90-0 single chemical entity Component is a metabolite of the substance (3RS)-3-(4-chlorophenyl)-3-{[N-(isopropoxycarbonyl)-L-valyl]amino}propanoic acid (3RS)-3-(4-chlorophenyl)-3-{[N-(isopropoxycarbonyl)-L-valyl]amino}propanoic acid Not in list C18H25ClN2O5 Clc1ccc(cc1)C(NC(=O)[C@@H](NC(=O)OC(C)C)C(C)C)CC(O)=O InChI=1/C18H25ClN2O5/c1-10(2)16(21-18(25)26-11(3)4)17(24)20-14(9-15(22)23)12-5-7-13(19)8-6-12/h5-8,10-11,14,16H,9H2,1-4H3,(H,20,24)(H,21,25)(H,22,23)/t14?,16-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Hungary Valifenalate (Formerly Valiphenal) (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate. 20Jun2013 2013 doi:10.2903/j.efsa.2013.3253
+Valiphenal 283159-90-0 single chemical entity Component is a metabolite of the substance (3RS)-3-(4-chlorophenyl)-3-{[N-(isopropoxycarbonyl)-L-valyl]amino}propanoic acid (3RS)-3-(4-chlorophenyl)-3-{[N-(isopropoxycarbonyl)-L-valyl]amino}propanoic acid Not in list C18H25ClN2O5 Clc1ccc(cc1)C(NC(=O)[C@@H](NC(=O)OC(C)C)C(C)C)CC(O)=O InChI=1/C18H25ClN2O5/c1-10(2)16(21-18(25)26-11(3)4)17(24)20-14(9-15(22)23)12-5-7-13(19)8-6-12/h5-8,10-11,14,16H,9H2,1-4H3,(H,20,24)(H,21,25)(H,22,23)/t14?,16-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Hungary Valifenalate (Formerly Valiphenal) (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate. 20Jun2013 2013 doi:10.2903/j.efsa.2013.3253
+Valiphenal 283159-90-0 single chemical entity Component is a metabolite of the substance (3RS)-3-(4-chlorophenyl)-3-{[N-(isopropoxycarbonyl)-L-valyl]amino}propanoic acid (3RS)-3-(4-chlorophenyl)-3-{[N-(isopropoxycarbonyl)-L-valyl]amino}propanoic acid Not in list C18H25ClN2O5 Clc1ccc(cc1)C(NC(=O)[C@@H](NC(=O)OC(C)C)C(C)C)CC(O)=O InChI=1/C18H25ClN2O5/c1-10(2)16(21-18(25)26-11(3)4)17(24)20-14(9-15(22)23)12-5-7-13(19)8-6-12/h5-8,10-11,14,16H,9H2,1-4H3,(H,20,24)(H,21,25)(H,22,23)/t14?,16-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Hungary Valifenalate (Formerly Valiphenal) (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate. 20Jun2013 2013 doi:10.2903/j.efsa.2013.3253
+Valiphenal 283159-90-0 single chemical entity Component is a metabolite of the substance (3RS)-3-(4-chlorophenyl)-3-{[N-(isopropoxycarbonyl)-L-valyl]amino}propanoic acid (3RS)-3-(4-chlorophenyl)-3-{[N-(isopropoxycarbonyl)-L-valyl]amino}propanoic acid Not in list C18H25ClN2O5 Clc1ccc(cc1)C(NC(=O)[C@@H](NC(=O)OC(C)C)C(C)C)CC(O)=O InChI=1/C18H25ClN2O5/c1-10(2)16(21-18(25)26-11(3)4)17(24)20-14(9-15(22)23)12-5-7-13(19)8-6-12/h5-8,10-11,14,16H,9H2,1-4H3,(H,20,24)(H,21,25)(H,22,23)/t14?,16-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Hungary Valifenalate (Formerly Valiphenal) (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate. 20Jun2013 2013 doi:10.2903/j.efsa.2013.3253
+Valiphenal 283159-90-0 single chemical entity Component is a metabolite of the substance (3RS)-3-(4-chlorophenyl)-3-{[N-(isopropoxycarbonyl)-L-valyl]amino}propanoic acid (3RS)-3-(4-chlorophenyl)-3-{[N-(isopropoxycarbonyl)-L-valyl]amino}propanoic acid Not in list C18H25ClN2O5 Clc1ccc(cc1)C(NC(=O)[C@@H](NC(=O)OC(C)C)C(C)C)CC(O)=O InChI=1/C18H25ClN2O5/c1-10(2)16(21-18(25)26-11(3)4)17(24)20-14(9-15(22)23)12-5-7-13(19)8-6-12/h5-8,10-11,14,16H,9H2,1-4H3,(H,20,24)(H,21,25)(H,22,23)/t14?,16-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Hungary Valifenalate (Formerly Valiphenal) (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate. 20Jun2013 2013 doi:10.2903/j.efsa.2013.3253
+Valiphenal 283159-90-0 single chemical entity Component is a metabolite of the substance (3RS)-3-(4-chlorophenyl)-3-{[N-(isopropoxycarbonyl)-L-valyl]amino}propanoic acid (3RS)-3-(4-chlorophenyl)-3-{[N-(isopropoxycarbonyl)-L-valyl]amino}propanoic acid Not in list C18H25ClN2O5 Clc1ccc(cc1)C(NC(=O)[C@@H](NC(=O)OC(C)C)C(C)C)CC(O)=O InChI=1/C18H25ClN2O5/c1-10(2)16(21-18(25)26-11(3)4)17(24)20-14(9-15(22)23)12-5-7-13(19)8-6-12/h5-8,10-11,14,16H,9H2,1-4H3,(H,20,24)(H,21,25)(H,22,23)/t14?,16-/m0/s1 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Hungary Valifenalate (Formerly Valiphenal) (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate. 20Jun2013 2013 doi:10.2903/j.efsa.2013.3253
+Valiphenal 283159-90-0 single chemical entity Component is a metabolite of the substance (3RS)-3-(4-chlorophenyl)-3-{[N-(isopropoxycarbonyl)-L-valyl]amino}propanoic acid (3RS)-3-(4-chlorophenyl)-3-{[N-(isopropoxycarbonyl)-L-valyl]amino}propanoic acid Not in list C18H25ClN2O5 Clc1ccc(cc1)C(NC(=O)[C@@H](NC(=O)OC(C)C)C(C)C)CC(O)=O InChI=1/C18H25ClN2O5/c1-10(2)16(21-18(25)26-11(3)4)17(24)20-14(9-15(22)23)12-5-7-13(19)8-6-12/h5-8,10-11,14,16H,9H2,1-4H3,(H,20,24)(H,21,25)(H,22,23)/t14?,16-/m0/s1 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Hungary Valifenalate (Formerly Valiphenal) (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate. 20Jun2013 2013 doi:10.2903/j.efsa.2013.3253
+Valiphenal 283159-90-0 single chemical entity Component is a metabolite of the substance (3RS)-3-(4-chlorophenyl)-3-{[N-(isopropoxycarbonyl)-L-valyl]amino}propanoic acid (3RS)-3-(4-chlorophenyl)-3-{[N-(isopropoxycarbonyl)-L-valyl]amino}propanoic acid Not in list C18H25ClN2O5 Clc1ccc(cc1)C(NC(=O)[C@@H](NC(=O)OC(C)C)C(C)C)CC(O)=O InChI=1/C18H25ClN2O5/c1-10(2)16(21-18(25)26-11(3)4)17(24)20-14(9-15(22)23)12-5-7-13(19)8-6-12/h5-8,10-11,14,16H,9H2,1-4H3,(H,20,24)(H,21,25)(H,22,23)/t14?,16-/m0/s1 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes without Positive RMS: Hungary Valifenalate (Formerly Valiphenal) (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate. 20Jun2013 2013 doi:10.2903/j.efsa.2013.3253
+Valiphenal 283159-90-0 single chemical entity Component is a metabolite of the substance (3RS)-3-(4-chlorophenyl)-3-{[N-(isopropoxycarbonyl)-L-valyl]amino}propanoic acid (3RS)-3-(4-chlorophenyl)-3-{[N-(isopropoxycarbonyl)-L-valyl]amino}propanoic acid Not in list C18H25ClN2O5 Clc1ccc(cc1)C(NC(=O)[C@@H](NC(=O)OC(C)C)C(C)C)CC(O)=O InChI=1/C18H25ClN2O5/c1-10(2)16(21-18(25)26-11(3)4)17(24)20-14(9-15(22)23)12-5-7-13(19)8-6-12/h5-8,10-11,14,16H,9H2,1-4H3,(H,20,24)(H,21,25)(H,22,23)/t14?,16-/m0/s1 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes with Negative RMS: Hungary Valifenalate (Formerly Valiphenal) (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate. 20Jun2013 2013 doi:10.2903/j.efsa.2013.3253
+Valiphenal 283159-90-0 single chemical entity Component is a metabolite of the substance 4-Chlorobenzoic acid 200-805-9 74-11-3 4-Chlorobenzoic acid Not in list C7H5ClO2 C1=CC(=CC=C1C(=O)O)Cl InChI=1S/C7H5ClO2/c8-6-3-1-5(2-4-6)7(9)10/h1-4H,(H,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative no information RMS: Hungary Valifenalate (Formerly Valiphenal) (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate. 20Jun2013 2013 doi:10.2903/j.efsa.2013.3253
+Valiphenal 283159-90-0 single chemical entity Component is a metabolite of the substance 4-Chlorobenzoic acid 200-805-9 74-11-3 4-Chlorobenzoic acid Not in list C7H5ClO2 C1=CC(=CC=C1C(=O)O)Cl InChI=1S/C7H5ClO2/c8-6-3-1-5(2-4-6)7(9)10/h1-4H,(H,9,10) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Negative no information RMS: Hungary Valifenalate (Formerly Valiphenal) (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate. 20Jun2013 2013 doi:10.2903/j.efsa.2013.3253
+Valiphenal 283159-90-0 single chemical entity Component is a metabolite of the substance 4-Chlorobenzoic acid 200-805-9 74-11-3 4-Chlorobenzoic acid Not in list C7H5ClO2 C1=CC(=CC=C1C(=O)O)Cl InChI=1S/C7H5ClO2/c8-6-3-1-5(2-4-6)7(9)10/h1-4H,(H,9,10) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes without Positive RMS: Hungary Valifenalate (Formerly Valiphenal) (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate. 20Jun2013 2013 doi:10.2903/j.efsa.2013.3253
+Valiphenal 283159-90-0 single chemical entity Component is a metabolite of the substance 4-Chlorobenzoic acid 200-805-9 74-11-3 4-Chlorobenzoic acid Not in list C7H5ClO2 C1=CC(=CC=C1C(=O)O)Cl InChI=1S/C7H5ClO2/c8-6-3-1-5(2-4-6)7(9)10/h1-4H,(H,9,10) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes with Negative RMS: Hungary Valifenalate (Formerly Valiphenal) (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate. 20Jun2013 2013 doi:10.2903/j.efsa.2013.3253
+Valiphenal 283159-90-0 single chemical entity Component is a metabolite of the substance (3RS)-3-(4-chlorophenyl)-3-{[N-(isopropoxycarbonyl)-L-valyl]amino}propanoic acid (3RS)-3-(4-chlorophenyl)-3-{[N-(isopropoxycarbonyl)-L-valyl]amino}propanoic acid Not in list C18H25ClN2O5 Clc1ccc(cc1)C(NC(=O)[C@@H](NC(=O)OC(C)C)C(C)C)CC(O)=O InChI=1/C18H25ClN2O5/c1-10(2)16(21-18(25)26-11(3)4)17(24)20-14(9-15(22)23)12-5-7-13(19)8-6-12/h5-8,10-11,14,16H,9H2,1-4H3,(H,20,24)(H,21,25)(H,22,23)/t14?,16-/m0/s1 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 48.0000000000 h yes not applicable Negative no evidence RMS: Hungary Valifenalate (Formerly Valiphenal) (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate. 20Jun2013 2013 doi:10.2903/j.efsa.2013.3253
+Valiphenal 283159-90-0 single chemical entity Component is a metabolite of the substance (3RS)-3-(4-chlorophenyl)-3-{[N-(isopropoxycarbonyl)-L-valyl]amino}propanoic acid (3RS)-3-(4-chlorophenyl)-3-{[N-(isopropoxycarbonyl)-L-valyl]amino}propanoic acid Not in list C18H25ClN2O5 Clc1ccc(cc1)C(NC(=O)[C@@H](NC(=O)OC(C)C)C(C)C)CC(O)=O InChI=1/C18H25ClN2O5/c1-10(2)16(21-18(25)26-11(3)4)17(24)20-14(9-15(22)23)12-5-7-13(19)8-6-12/h5-8,10-11,14,16H,9H2,1-4H3,(H,20,24)(H,21,25)(H,22,23)/t14?,16-/m0/s1 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 24.0000000000 h yes not applicable Negative no evidence RMS: Hungary Valifenalate (Formerly Valiphenal) (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate. 20Jun2013 2013 doi:10.2903/j.efsa.2013.3253
+Valiphenal 283159-90-0 single chemical entity Component is a metabolite of the substance 4-Chlorobenzoic acid 200-805-9 74-11-3 4-Chlorobenzoic acid Not in list C7H5ClO2 C1=CC(=CC=C1C(=O)O)Cl InChI=1S/C7H5ClO2/c8-6-3-1-5(2-4-6)7(9)10/h1-4H,(H,9,10) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 48.0000000000 h yes not applicable Negative no evidence RMS: Hungary Valifenalate (Formerly Valiphenal) (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate. 20Jun2013 2013 doi:10.2903/j.efsa.2013.3253
+Valiphenal 283159-90-0 single chemical entity Component is a metabolite of the substance 4-Chlorobenzoic acid 200-805-9 74-11-3 4-Chlorobenzoic acid Not in list C7H5ClO2 C1=CC(=CC=C1C(=O)O)Cl InChI=1S/C7H5ClO2/c8-6-3-1-5(2-4-6)7(9)10/h1-4H,(H,9,10) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 24.0000000000 h yes not applicable Negative no evidence RMS: Hungary Valifenalate (Formerly Valiphenal) (Final Addendum) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate. 20Jun2013 2013 doi:10.2903/j.efsa.2013.3253
+Trifluralin 216-428-8 1582-09-8 single chemical entity Component is identical to the substance Trifluralin 216-428-8 1582-09-8 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline Trifluralin C13H16F3N3O4 CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Greece Trifluralin 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance trifluralin 05Aug2009 2009 doi:10.2903/j.efsa.2009.327r
+Trifluralin 216-428-8 1582-09-8 single chemical entity Component is identical to the substance Trifluralin 216-428-8 1582-09-8 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline Trifluralin C13H16F3N3O4 CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Greece Trifluralin 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance trifluralin 05Aug2009 2009 doi:10.2903/j.efsa.2009.327r
+Trifluralin 216-428-8 1582-09-8 single chemical entity Component is identical to the substance Trifluralin 216-428-8 1582-09-8 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline Trifluralin C13H16F3N3O4 CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Greece Trifluralin 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance trifluralin 05Aug2009 2009 doi:10.2903/j.efsa.2009.327r
+Trifluralin 216-428-8 1582-09-8 single chemical entity Component is identical to the substance Trifluralin 216-428-8 1582-09-8 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline Trifluralin C13H16F3N3O4 CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Greece Trifluralin 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance trifluralin 05Aug2009 2009 doi:10.2903/j.efsa.2009.327r
+Trifluralin 216-428-8 1582-09-8 single chemical entity Component is identical to the substance Trifluralin 216-428-8 1582-09-8 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline Trifluralin C13H16F3N3O4 CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Greece Trifluralin 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance trifluralin 05Aug2009 2009 doi:10.2903/j.efsa.2009.327r
+Trifluralin 216-428-8 1582-09-8 single chemical entity Component is identical to the substance Trifluralin 216-428-8 1582-09-8 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline Trifluralin C13H16F3N3O4 CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Greece Trifluralin 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance trifluralin 05Aug2009 2009 doi:10.2903/j.efsa.2009.327r
+Trifluralin 216-428-8 1582-09-8 single chemical entity Component is identical to the substance Trifluralin 216-428-8 1582-09-8 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline Trifluralin C13H16F3N3O4 CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Greece Trifluralin 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance trifluralin 05Aug2009 2009 doi:10.2903/j.efsa.2009.327r
+Trifluralin 216-428-8 1582-09-8 single chemical entity Component is identical to the substance Trifluralin 216-428-8 1582-09-8 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline Trifluralin C13H16F3N3O4 CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Greece Trifluralin 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance trifluralin 05Aug2009 2009 doi:10.2903/j.efsa.2009.327r
+Trifluralin 216-428-8 1582-09-8 single chemical entity Component is identical to the substance Trifluralin 216-428-8 1582-09-8 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline Trifluralin C13H16F3N3O4 CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Greece Trifluralin 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance trifluralin 05Aug2009 2009 doi:10.2903/j.efsa.2009.327r
+Trifluralin 216-428-8 1582-09-8 single chemical entity Component is identical to the substance Trifluralin 216-428-8 1582-09-8 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline Trifluralin C13H16F3N3O4 CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Greece Trifluralin 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance trifluralin 05Aug2009 2009 doi:10.2903/j.efsa.2009.327r
+Trifluralin 216-428-8 1582-09-8 single chemical entity Component is identical to the substance Trifluralin 216-428-8 1582-09-8 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline Trifluralin C13H16F3N3O4 CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Greece Trifluralin 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance trifluralin 05Aug2009 2009 doi:10.2903/j.efsa.2009.327r
+Trifluralin 216-428-8 1582-09-8 single chemical entity Component is identical to the substance Trifluralin 216-428-8 1582-09-8 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline Trifluralin C13H16F3N3O4 CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Greece Trifluralin 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance trifluralin 05Aug2009 2009 doi:10.2903/j.efsa.2009.327r
+Trifluralin 216-428-8 1582-09-8 single chemical entity Component is identical to the substance Trifluralin 216-428-8 1582-09-8 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline Trifluralin C13H16F3N3O4 CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Greece Trifluralin 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance trifluralin 05Aug2009 2009 doi:10.2903/j.efsa.2009.327r
+Trifluralin 216-428-8 1582-09-8 single chemical entity Component is identical to the substance Trifluralin 216-428-8 1582-09-8 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline Trifluralin C13H16F3N3O4 CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Greece Trifluralin 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance trifluralin 05Aug2009 2009 doi:10.2903/j.efsa.2009.327r
+Trifluralin 216-428-8 1582-09-8 single chemical entity Component is identical to the substance Trifluralin 216-428-8 1582-09-8 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline Trifluralin C13H16F3N3O4 CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Greece Trifluralin 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance trifluralin 05Aug2009 2009 doi:10.2903/j.efsa.2009.327r
+Trifluralin 216-428-8 1582-09-8 single chemical entity Component is identical to the substance Trifluralin 216-428-8 1582-09-8 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline Trifluralin C13H16F3N3O4 CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Greece Trifluralin 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance trifluralin 05Aug2009 2009 doi:10.2903/j.efsa.2009.327r
+Trifluralin 216-428-8 1582-09-8 single chemical entity Component is identical to the substance Trifluralin 216-428-8 1582-09-8 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline Trifluralin C13H16F3N3O4 CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Greece Trifluralin 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance trifluralin 05Aug2009 2009 doi:10.2903/j.efsa.2009.327r
+Trifluralin 216-428-8 1582-09-8 single chemical entity Component is identical to the substance Trifluralin 216-428-8 1582-09-8 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline Trifluralin C13H16F3N3O4 CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Greece Trifluralin 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance trifluralin 05Aug2009 2009 doi:10.2903/j.efsa.2009.327r
+Trifluralin 216-428-8 1582-09-8 single chemical entity Component is identical to the substance Trifluralin 216-428-8 1582-09-8 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline Trifluralin C13H16F3N3O4 CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Greece Trifluralin 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance trifluralin 05Aug2009 2009 doi:10.2903/j.efsa.2009.327r
+Trifluralin 216-428-8 1582-09-8 single chemical entity Component is identical to the substance Trifluralin 216-428-8 1582-09-8 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline Trifluralin C13H16F3N3O4 CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Greece Trifluralin 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance trifluralin 05Aug2009 2009 doi:10.2903/j.efsa.2009.327r
+Trifluralin 216-428-8 1582-09-8 single chemical entity Component is identical to the substance Trifluralin 216-428-8 1582-09-8 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline Trifluralin C13H16F3N3O4 CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Greece Trifluralin 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance trifluralin 05Aug2009 2009 doi:10.2903/j.efsa.2009.327r
+Trifluralin 216-428-8 1582-09-8 single chemical entity Component is identical to the substance Trifluralin 216-428-8 1582-09-8 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline Trifluralin C13H16F3N3O4 CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Greece Trifluralin 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance trifluralin 05Aug2009 2009 doi:10.2903/j.efsa.2009.327r
+Trifluralin 216-428-8 1582-09-8 single chemical entity Component is identical to the substance Trifluralin 216-428-8 1582-09-8 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline Trifluralin C13H16F3N3O4 CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Greece Trifluralin 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance trifluralin 05Aug2009 2009 doi:10.2903/j.efsa.2009.327r
+Trifluralin 216-428-8 1582-09-8 single chemical entity Component is identical to the substance Trifluralin 216-428-8 1582-09-8 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline Trifluralin C13H16F3N3O4 CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Greece Trifluralin 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance trifluralin 05Aug2009 2009 doi:10.2903/j.efsa.2009.327r
+Trifluralin 216-428-8 1582-09-8 single chemical entity Component is identical to the substance Trifluralin 216-428-8 1582-09-8 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline Trifluralin C13H16F3N3O4 CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Greece Trifluralin 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance trifluralin 05Aug2009 2009 doi:10.2903/j.efsa.2009.327r
+Trifluralin 216-428-8 1582-09-8 single chemical entity Component is identical to the substance Trifluralin 216-428-8 1582-09-8 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline Trifluralin C13H16F3N3O4 CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Greece Trifluralin 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance trifluralin 05Aug2009 2009 doi:10.2903/j.efsa.2009.327r
+Trifluralin 216-428-8 1582-09-8 single chemical entity Component is identical to the substance Trifluralin 216-428-8 1582-09-8 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline Trifluralin C13H16F3N3O4 CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Greece Trifluralin 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance trifluralin 05Aug2009 2009 doi:10.2903/j.efsa.2009.327r
+Trifluralin 216-428-8 1582-09-8 single chemical entity Component is identical to the substance Trifluralin 216-428-8 1582-09-8 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline Trifluralin C13H16F3N3O4 CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Greece Trifluralin 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance trifluralin 05Aug2009 2009 doi:10.2903/j.efsa.2009.327r
+Trifluralin 216-428-8 1582-09-8 single chemical entity Component is identical to the substance Trifluralin 216-428-8 1582-09-8 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline Trifluralin C13H16F3N3O4 CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Greece Trifluralin 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance trifluralin 05Aug2009 2009 doi:10.2903/j.efsa.2009.327r
+Trifluralin 216-428-8 1582-09-8 single chemical entity Component is identical to the substance Trifluralin 216-428-8 1582-09-8 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline Trifluralin C13H16F3N3O4 CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Greece Trifluralin 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance trifluralin 05Aug2009 2009 doi:10.2903/j.efsa.2009.327r
+Trifluralin 216-428-8 1582-09-8 single chemical entity Component is identical to the substance Trifluralin 216-428-8 1582-09-8 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline Trifluralin C13H16F3N3O4 CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Greece Trifluralin 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance trifluralin 05Aug2009 2009 doi:10.2903/j.efsa.2009.327r
+Trifluralin 216-428-8 1582-09-8 single chemical entity Component is identical to the substance Trifluralin 216-428-8 1582-09-8 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline Trifluralin C13H16F3N3O4 CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Greece Trifluralin 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance trifluralin 05Aug2009 2009 doi:10.2903/j.efsa.2009.327r
+Trifluralin 216-428-8 1582-09-8 single chemical entity Component is identical to the substance Trifluralin 216-428-8 1582-09-8 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline Trifluralin C13H16F3N3O4 CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Greece Trifluralin 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance trifluralin 05Aug2009 2009 doi:10.2903/j.efsa.2009.327r
+Trifluralin 216-428-8 1582-09-8 single chemical entity Component is identical to the substance Trifluralin 216-428-8 1582-09-8 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline Trifluralin C13H16F3N3O4 CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Greece Trifluralin 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance trifluralin 05Aug2009 2009 doi:10.2903/j.efsa.2009.327r
+Trifluralin 216-428-8 1582-09-8 single chemical entity Component is identical to the substance Trifluralin 216-428-8 1582-09-8 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline Trifluralin C13H16F3N3O4 CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Greece Trifluralin 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance trifluralin 05Aug2009 2009 doi:10.2903/j.efsa.2009.327r
+Trifluralin 216-428-8 1582-09-8 single chemical entity Component is identical to the substance Trifluralin 216-428-8 1582-09-8 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline Trifluralin C13H16F3N3O4 CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Greece Trifluralin 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance trifluralin 05Aug2009 2009 doi:10.2903/j.efsa.2009.327r
+Trifluralin 216-428-8 1582-09-8 single chemical entity Component is identical to the substance Trifluralin 216-428-8 1582-09-8 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline Trifluralin C13H16F3N3O4 CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes without Negative RMS: Greece Trifluralin 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance trifluralin 05Aug2009 2009 doi:10.2903/j.efsa.2009.327r
+Trifluralin 216-428-8 1582-09-8 single chemical entity Component is identical to the substance Trifluralin 216-428-8 1582-09-8 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline Trifluralin C13H16F3N3O4 CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Greece Trifluralin 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance trifluralin 05Aug2009 2009 doi:10.2903/j.efsa.2009.327r
+Trifluralin 216-428-8 1582-09-8 single chemical entity Component is identical to the substance Trifluralin 216-428-8 1582-09-8 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline Trifluralin C13H16F3N3O4 CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Greece Trifluralin 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance trifluralin 05Aug2009 2009 doi:10.2903/j.efsa.2009.327r
+Trifluralin 216-428-8 1582-09-8 single chemical entity Component is identical to the substance Trifluralin 216-428-8 1582-09-8 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline Trifluralin C13H16F3N3O4 CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro According to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No Acceptable Human (as organism) lymphocytes Not reported yes without Positive RMS: Greece Trifluralin 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance trifluralin 05Aug2009 2009 doi:10.2903/j.efsa.2009.327r
+Trifluralin 216-428-8 1582-09-8 single chemical entity Component is identical to the substance Trifluralin 216-428-8 1582-09-8 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline Trifluralin C13H16F3N3O4 CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro According to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No Acceptable Human (as organism) lymphocytes Not reported yes with Positive RMS: Greece Trifluralin 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance trifluralin 05Aug2009 2009 doi:10.2903/j.efsa.2009.327r
+Trifluralin 216-428-8 1582-09-8 single chemical entity Component is identical to the substance Trifluralin 216-428-8 1582-09-8 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline Trifluralin C13H16F3N3O4 CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound Other Other DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vitro No guideline available Not reported Not applicable Acceptable Human (as organism) lymphocytes Not reported yes with Positive RMS: Greece Trifluralin 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance trifluralin 05Aug2009 2009 doi:10.2903/j.efsa.2009.327r
+Trifluralin 216-428-8 1582-09-8 single chemical entity Component is identical to the substance Trifluralin 216-428-8 1582-09-8 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline Trifluralin C13H16F3N3O4 CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound Other Other DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vitro No guideline required Not reported Not applicable Acceptable Human (as organism) lymphocytes Not reported yes without Positive RMS: Greece Trifluralin 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance trifluralin 05Aug2009 2009 doi:10.2903/j.efsa.2009.327r
+Trifluralin 216-428-8 1582-09-8 single chemical entity Component is identical to the substance Trifluralin 216-428-8 1582-09-8 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline Trifluralin C13H16F3N3O4 CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound Other Other chromosome aberration in vitro mammalian cell micronucleus test in vitro Equivalent or similar to OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes not applicable Positive RMS: Greece Trifluralin 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance trifluralin 05Aug2009 2009 doi:10.2903/j.efsa.2009.327r
+Trifluralin 216-428-8 1582-09-8 single chemical entity Component is identical to the substance Trifluralin 216-428-8 1582-09-8 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline Trifluralin C13H16F3N3O4 CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vivo No guideline available Not reported Not applicable Acceptable Hamster (as animal) Not reported 3 Female oral: gavage 2.0000000000 D yes not applicable Negative RMS: Greece Trifluralin 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance trifluralin 05Aug2009 2009 doi:10.2903/j.efsa.2009.327r
+Trifluralin 216-428-8 1582-09-8 single chemical entity Component is identical to the substance Trifluralin 216-428-8 1582-09-8 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline Trifluralin C13H16F3N3O4 CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound Other Other chromosome aberration mammalian germ cell cytogenetic assay in vivo Equivalent or similar to OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test) Yes Acceptable House mouse (as animal) ICR 5 Female oral: gavage 5.0000000000 D yes not applicable Negative RMS: Greece Trifluralin 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance trifluralin 05Aug2009 2009 doi:10.2903/j.efsa.2009.327r
+Trifluralin 216-428-8 1582-09-8 single chemical entity Component is identical to the substance Trifluralin 216-428-8 1582-09-8 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline Trifluralin C13H16F3N3O4 CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Sprague-Dawley 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Greece Trifluralin 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance trifluralin 05Aug2009 2009 doi:10.2903/j.efsa.2009.327r
+Trifluralin 216-428-8 1582-09-8 single chemical entity Component is identical to the substance Trifluralin 216-428-8 1582-09-8 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline Trifluralin C13H16F3N3O4 CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Sprague-Dawley 10 Male/Female oral: gavage 6.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Greece Trifluralin 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance trifluralin 05Aug2009 2009 doi:10.2903/j.efsa.2009.327r
+Trifluralin 216-428-8 1582-09-8 single chemical entity Component is identical to the substance Trifluralin 216-428-8 1582-09-8 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline Trifluralin C13H16F3N3O4 CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Sprague-Dawley 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Greece Trifluralin 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance trifluralin 05Aug2009 2009 doi:10.2903/j.efsa.2009.327r
+Trifluralin 216-428-8 1582-09-8 single chemical entity Component is identical to the substance Trifluralin 216-428-8 1582-09-8 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline Trifluralin C13H16F3N3O4 CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 4 Male/Female oral: gavage 48.0000000000 h yes not applicable Positive no evidence RMS: Greece Trifluralin 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance trifluralin 05Aug2009 2009 doi:10.2903/j.efsa.2009.327r
+Trifluralin 216-428-8 1582-09-8 single chemical entity Component is identical to the substance Trifluralin 216-428-8 1582-09-8 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline Trifluralin C13H16F3N3O4 CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound Other Other chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) Yes Acceptable Rat (as animal) Wistar 15 Male oral: gavage 5.0000000000 D yes not applicable Negative RMS: Greece Trifluralin 2003 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance trifluralin 05Aug2009 2009 doi:10.2903/j.efsa.2009.327r
+Sintofen (aka cintofen) 130561-48-7 single chemical entity Component is identical to the substance Sintofen (aka cintofen) 130561-48-7 1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid Sintofen (aka cintofen) C18H15ClN2O5 O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: France Sintofen (revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen 14Dec2010 2010 doi:10.2903/j.efsa.2010.1931
+Sintofen (aka cintofen) 130561-48-7 single chemical entity Component is identical to the substance Sintofen (aka cintofen) 130561-48-7 1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid Sintofen (aka cintofen) C18H15ClN2O5 O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Sintofen (revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen 14Dec2010 2010 doi:10.2903/j.efsa.2010.1931
+Sintofen (aka cintofen) 130561-48-7 single chemical entity Component is identical to the substance Sintofen (aka cintofen) 130561-48-7 1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid Sintofen (aka cintofen) C18H15ClN2O5 O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Sintofen (revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen 14Dec2010 2010 doi:10.2903/j.efsa.2010.1931
+Sintofen (aka cintofen) 130561-48-7 single chemical entity Component is identical to the substance Sintofen (aka cintofen) 130561-48-7 1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid Sintofen (aka cintofen) C18H15ClN2O5 O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Sintofen (revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen 14Dec2010 2010 doi:10.2903/j.efsa.2010.1931
+Sintofen (aka cintofen) 130561-48-7 single chemical entity Component is identical to the substance Sintofen (aka cintofen) 130561-48-7 1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid Sintofen (aka cintofen) C18H15ClN2O5 O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Sintofen (revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen 14Dec2010 2010 doi:10.2903/j.efsa.2010.1931
+Sintofen (aka cintofen) 130561-48-7 single chemical entity Component is identical to the substance Sintofen (aka cintofen) 130561-48-7 1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid Sintofen (aka cintofen) C18H15ClN2O5 O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: France Sintofen (revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen 14Dec2010 2010 doi:10.2903/j.efsa.2010.1931
+Sintofen (aka cintofen) 130561-48-7 single chemical entity Component is identical to the substance Sintofen (aka cintofen) 130561-48-7 1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid Sintofen (aka cintofen) C18H15ClN2O5 O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Sintofen (revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen 14Dec2010 2010 doi:10.2903/j.efsa.2010.1931
+Sintofen (aka cintofen) 130561-48-7 single chemical entity Component is identical to the substance Sintofen (aka cintofen) 130561-48-7 1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid Sintofen (aka cintofen) C18H15ClN2O5 O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Sintofen (revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen 14Dec2010 2010 doi:10.2903/j.efsa.2010.1931
+Sintofen (aka cintofen) 130561-48-7 single chemical entity Component is identical to the substance Sintofen (aka cintofen) 130561-48-7 1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid Sintofen (aka cintofen) C18H15ClN2O5 O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Sintofen (revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen 14Dec2010 2010 doi:10.2903/j.efsa.2010.1931
+Sintofen (aka cintofen) 130561-48-7 single chemical entity Component is identical to the substance Sintofen (aka cintofen) 130561-48-7 1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid Sintofen (aka cintofen) C18H15ClN2O5 O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Sintofen (revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen 14Dec2010 2010 doi:10.2903/j.efsa.2010.1931
+Sintofen (aka cintofen) 130561-48-7 single chemical entity Component is identical to the substance Sintofen (aka cintofen) 130561-48-7 1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid Sintofen (aka cintofen) C18H15ClN2O5 O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Sintofen (revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen 14Dec2010 2010 doi:10.2903/j.efsa.2010.1931
+Sintofen (aka cintofen) 130561-48-7 single chemical entity Component is identical to the substance Sintofen (aka cintofen) 130561-48-7 1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid Sintofen (aka cintofen) C18H15ClN2O5 O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: France Sintofen (revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen 14Dec2010 2010 doi:10.2903/j.efsa.2010.1931
+Sintofen (aka cintofen) 130561-48-7 single chemical entity Component is identical to the substance Sintofen (aka cintofen) 130561-48-7 1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid Sintofen (aka cintofen) C18H15ClN2O5 O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Sintofen (revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen 14Dec2010 2010 doi:10.2903/j.efsa.2010.1931
+Sintofen (aka cintofen) 130561-48-7 single chemical entity Component is identical to the substance Sintofen (aka cintofen) 130561-48-7 1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid Sintofen (aka cintofen) C18H15ClN2O5 O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Sintofen (revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen 14Dec2010 2010 doi:10.2903/j.efsa.2010.1931
+Sintofen (aka cintofen) 130561-48-7 single chemical entity Component is identical to the substance Sintofen (aka cintofen) 130561-48-7 1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid Sintofen (aka cintofen) C18H15ClN2O5 O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Sintofen (revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen 14Dec2010 2010 doi:10.2903/j.efsa.2010.1931
+Sintofen (aka cintofen) 130561-48-7 single chemical entity Component is identical to the substance Sintofen (aka cintofen) 130561-48-7 1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid Sintofen (aka cintofen) C18H15ClN2O5 O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Sintofen (revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen 14Dec2010 2010 doi:10.2903/j.efsa.2010.1931
+Sintofen (aka cintofen) 130561-48-7 single chemical entity Component is identical to the substance Sintofen (aka cintofen) 130561-48-7 1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid Sintofen (aka cintofen) C18H15ClN2O5 O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: France Sintofen (revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen 14Dec2010 2010 doi:10.2903/j.efsa.2010.1931
+Sintofen (aka cintofen) 130561-48-7 single chemical entity Component is identical to the substance Sintofen (aka cintofen) 130561-48-7 1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid Sintofen (aka cintofen) C18H15ClN2O5 O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Sintofen (revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen 14Dec2010 2010 doi:10.2903/j.efsa.2010.1931
+Sintofen (aka cintofen) 130561-48-7 single chemical entity Component is identical to the substance Sintofen (aka cintofen) 130561-48-7 1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid Sintofen (aka cintofen) C18H15ClN2O5 O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Sintofen (revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen 14Dec2010 2010 doi:10.2903/j.efsa.2010.1931
+Sintofen (aka cintofen) 130561-48-7 single chemical entity Component is identical to the substance Sintofen (aka cintofen) 130561-48-7 1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid Sintofen (aka cintofen) C18H15ClN2O5 O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Sintofen (revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen 14Dec2010 2010 doi:10.2903/j.efsa.2010.1931
+Sintofen (aka cintofen) 130561-48-7 single chemical entity Component is identical to the substance Sintofen (aka cintofen) 130561-48-7 1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid Sintofen (aka cintofen) C18H15ClN2O5 O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: France Sintofen (revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen 14Dec2010 2010 doi:10.2903/j.efsa.2010.1931
+Sintofen (aka cintofen) 130561-48-7 single chemical entity Component is identical to the substance Sintofen (aka cintofen) 130561-48-7 1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid Sintofen (aka cintofen) C18H15ClN2O5 O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: France Sintofen (revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen 14Dec2010 2010 doi:10.2903/j.efsa.2010.1931
+Sintofen (aka cintofen) 130561-48-7 single chemical entity Component is identical to the substance Sintofen (aka cintofen) 130561-48-7 1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid Sintofen (aka cintofen) C18H15ClN2O5 O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: France Sintofen (revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen 14Dec2010 2010 doi:10.2903/j.efsa.2010.1931
+Sintofen (aka cintofen) 130561-48-7 single chemical entity Component is identical to the substance Sintofen (aka cintofen) 130561-48-7 1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid Sintofen (aka cintofen) C18H15ClN2O5 O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: France Sintofen (revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen 14Dec2010 2010 doi:10.2903/j.efsa.2010.1931
+Sintofen (aka cintofen) 130561-48-7 single chemical entity Component is identical to the substance Sintofen (aka cintofen) 130561-48-7 1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid Sintofen (aka cintofen) C18H15ClN2O5 O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24) organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Human (as organism) HeLa cells Not reported yes, concurrent vehicle without Negative RMS: France Sintofen (revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen 14Dec2010 2010 doi:10.2903/j.efsa.2010.1931
+Sintofen (aka cintofen) 130561-48-7 single chemical entity Component is identical to the substance Sintofen (aka cintofen) 130561-48-7 1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid Sintofen (aka cintofen) C18H15ClN2O5 O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24) organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Human (as organism) HeLa cells Not reported yes, concurrent vehicle with Negative RMS: France Sintofen (revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen 14Dec2010 2010 doi:10.2903/j.efsa.2010.1931
+Sintofen (aka cintofen) 130561-48-7 single chemical entity Component is identical to the substance Sintofen (aka cintofen) 130561-48-7 1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid Sintofen (aka cintofen) C18H15ClN2O5 O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Swiss 30 Male/Female oral: gavage 72.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: France Sintofen (revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen 14Dec2010 2010 doi:10.2903/j.efsa.2010.1931
+Sintofen (aka cintofen) 130561-48-7 single chemical entity Component is identical to the substance Sintofen (aka cintofen) 130561-48-7 1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid Sintofen (aka cintofen) C18H15ClN2O5 O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Swiss 30 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: France Sintofen (revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen 14Dec2010 2010 doi:10.2903/j.efsa.2010.1931
+Sintofen (aka cintofen) 130561-48-7 single chemical entity Component is identical to the substance Sintofen (aka cintofen) 130561-48-7 1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid Sintofen (aka cintofen) C18H15ClN2O5 O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Swiss 30 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: France Sintofen (revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen 14Dec2010 2010 doi:10.2903/j.efsa.2010.1931
+Sintofen (aka cintofen) 130561-48-7 single chemical entity Component is a metabolite of the substance 1-(-4’-chlorophenyl)-1,4-dihydro-5-(2’’-hydroxy-ethoxy)-4-oxo-cinnoline-3-carboxylate 1-(4-chlorophenyl)-5-(2-hydroxyethoxy)-4-oxo-1,4-dihydrocinnoline-3-carboxylic acid Sintofen metabolite (SC 3095) C17H13ClN2O5 OC(=O)C/2=N/N(c1ccc(Cl)cc1)c3cccc(OCCO)c3C\2=O InChI=1/C17H13ClN2O5/c18-10-4-6-11(7-5-10)20-12-2-1-3-13(25-9-8-21)14(12)16(22)15(19-20)17(23)24/h1-7,21H,8-9H2,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: France Sintofen (revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen 14Dec2010 2010 doi:10.2903/j.efsa.2010.1931
+Sintofen (aka cintofen) 130561-48-7 single chemical entity Component is a metabolite of the substance 1-(-4’-chlorophenyl)-1,4-dihydro-5-(2’’-hydroxy-ethoxy)-4-oxo-cinnoline-3-carboxylate 1-(4-chlorophenyl)-5-(2-hydroxyethoxy)-4-oxo-1,4-dihydrocinnoline-3-carboxylic acid Sintofen metabolite (SC 3095) C17H13ClN2O5 OC(=O)C/2=N/N(c1ccc(Cl)cc1)c3cccc(OCCO)c3C\2=O InChI=1/C17H13ClN2O5/c18-10-4-6-11(7-5-10)20-12-2-1-3-13(25-9-8-21)14(12)16(22)15(19-20)17(23)24/h1-7,21H,8-9H2,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: France Sintofen (revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen 14Dec2010 2010 doi:10.2903/j.efsa.2010.1931
+Sintofen (aka cintofen) 130561-48-7 single chemical entity Component is a metabolite of the substance 1-(-4’-chlorophenyl)-1,4-dihydro-5-(2’’-hydroxy-ethoxy)-4-oxo-cinnoline-3-carboxylate 1-(4-chlorophenyl)-5-(2-hydroxyethoxy)-4-oxo-1,4-dihydrocinnoline-3-carboxylic acid Sintofen metabolite (SC 3095) C17H13ClN2O5 OC(=O)C/2=N/N(c1ccc(Cl)cc1)c3cccc(OCCO)c3C\2=O InChI=1/C17H13ClN2O5/c18-10-4-6-11(7-5-10)20-12-2-1-3-13(25-9-8-21)14(12)16(22)15(19-20)17(23)24/h1-7,21H,8-9H2,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Sintofen (revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen 14Dec2010 2010 doi:10.2903/j.efsa.2010.1931
+Sintofen (aka cintofen) 130561-48-7 single chemical entity Component is a metabolite of the substance 1-(-4’-chlorophenyl)-1,4-dihydro-5-(2’’-hydroxy-ethoxy)-4-oxo-cinnoline-3-carboxylate 1-(4-chlorophenyl)-5-(2-hydroxyethoxy)-4-oxo-1,4-dihydrocinnoline-3-carboxylic acid Sintofen metabolite (SC 3095) C17H13ClN2O5 OC(=O)C/2=N/N(c1ccc(Cl)cc1)c3cccc(OCCO)c3C\2=O InChI=1/C17H13ClN2O5/c18-10-4-6-11(7-5-10)20-12-2-1-3-13(25-9-8-21)14(12)16(22)15(19-20)17(23)24/h1-7,21H,8-9H2,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Sintofen (revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen 14Dec2010 2010 doi:10.2903/j.efsa.2010.1931
+Sintofen (aka cintofen) 130561-48-7 single chemical entity Component is a metabolite of the substance 1-(-4’-chlorophenyl)-1,4-dihydro-5-(2’’-hydroxy-ethoxy)-4-oxo-cinnoline-3-carboxylate 1-(4-chlorophenyl)-5-(2-hydroxyethoxy)-4-oxo-1,4-dihydrocinnoline-3-carboxylic acid Sintofen metabolite (SC 3095) C17H13ClN2O5 OC(=O)C/2=N/N(c1ccc(Cl)cc1)c3cccc(OCCO)c3C\2=O InChI=1/C17H13ClN2O5/c18-10-4-6-11(7-5-10)20-12-2-1-3-13(25-9-8-21)14(12)16(22)15(19-20)17(23)24/h1-7,21H,8-9H2,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Sintofen (revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen 14Dec2010 2010 doi:10.2903/j.efsa.2010.1931
+Sintofen (aka cintofen) 130561-48-7 single chemical entity Component is a metabolite of the substance 1-(-4’-chlorophenyl)-1,4-dihydro-5-(2’’-hydroxy-ethoxy)-4-oxo-cinnoline-3-carboxylate 1-(4-chlorophenyl)-5-(2-hydroxyethoxy)-4-oxo-1,4-dihydrocinnoline-3-carboxylic acid Sintofen metabolite (SC 3095) C17H13ClN2O5 OC(=O)C/2=N/N(c1ccc(Cl)cc1)c3cccc(OCCO)c3C\2=O InChI=1/C17H13ClN2O5/c18-10-4-6-11(7-5-10)20-12-2-1-3-13(25-9-8-21)14(12)16(22)15(19-20)17(23)24/h1-7,21H,8-9H2,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Sintofen (revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen 14Dec2010 2010 doi:10.2903/j.efsa.2010.1931
+Sintofen (aka cintofen) 130561-48-7 single chemical entity Component is a metabolite of the substance 1-(-4’-chlorophenyl)-1,4-dihydro-5-(2’’-hydroxy-ethoxy)-4-oxo-cinnoline-3-carboxylate 1-(4-chlorophenyl)-5-(2-hydroxyethoxy)-4-oxo-1,4-dihydrocinnoline-3-carboxylic acid Sintofen metabolite (SC 3095) C17H13ClN2O5 OC(=O)C/2=N/N(c1ccc(Cl)cc1)c3cccc(OCCO)c3C\2=O InChI=1/C17H13ClN2O5/c18-10-4-6-11(7-5-10)20-12-2-1-3-13(25-9-8-21)14(12)16(22)15(19-20)17(23)24/h1-7,21H,8-9H2,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Sintofen (revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen 14Dec2010 2010 doi:10.2903/j.efsa.2010.1931
+Sintofen (aka cintofen) 130561-48-7 single chemical entity Component is a metabolite of the substance 1-(-4’-chlorophenyl)-1,4-dihydro-5-(2’’-hydroxy-ethoxy)-4-oxo-cinnoline-3-carboxylate 1-(4-chlorophenyl)-5-(2-hydroxyethoxy)-4-oxo-1,4-dihydrocinnoline-3-carboxylic acid Sintofen metabolite (SC 3095) C17H13ClN2O5 OC(=O)C/2=N/N(c1ccc(Cl)cc1)c3cccc(OCCO)c3C\2=O InChI=1/C17H13ClN2O5/c18-10-4-6-11(7-5-10)20-12-2-1-3-13(25-9-8-21)14(12)16(22)15(19-20)17(23)24/h1-7,21H,8-9H2,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Sintofen (revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen 14Dec2010 2010 doi:10.2903/j.efsa.2010.1931
+Sintofen (aka cintofen) 130561-48-7 single chemical entity Component is a metabolite of the substance 1-(-4’-chlorophenyl)-1,4-dihydro-5-(2’’-hydroxy-ethoxy)-4-oxo-cinnoline-3-carboxylate 1-(4-chlorophenyl)-5-(2-hydroxyethoxy)-4-oxo-1,4-dihydrocinnoline-3-carboxylic acid Sintofen metabolite (SC 3095) C17H13ClN2O5 OC(=O)C/2=N/N(c1ccc(Cl)cc1)c3cccc(OCCO)c3C\2=O InChI=1/C17H13ClN2O5/c18-10-4-6-11(7-5-10)20-12-2-1-3-13(25-9-8-21)14(12)16(22)15(19-20)17(23)24/h1-7,21H,8-9H2,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Sintofen (revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen 14Dec2010 2010 doi:10.2903/j.efsa.2010.1931
+Sintofen (aka cintofen) 130561-48-7 single chemical entity Component is a metabolite of the substance 1-(-4’-chlorophenyl)-1,4-dihydro-5-(2’’-hydroxy-ethoxy)-4-oxo-cinnoline-3-carboxylate 1-(4-chlorophenyl)-5-(2-hydroxyethoxy)-4-oxo-1,4-dihydrocinnoline-3-carboxylic acid Sintofen metabolite (SC 3095) C17H13ClN2O5 OC(=O)C/2=N/N(c1ccc(Cl)cc1)c3cccc(OCCO)c3C\2=O InChI=1/C17H13ClN2O5/c18-10-4-6-11(7-5-10)20-12-2-1-3-13(25-9-8-21)14(12)16(22)15(19-20)17(23)24/h1-7,21H,8-9H2,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Sintofen (revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen 14Dec2010 2010 doi:10.2903/j.efsa.2010.1931
+Sintofen (aka cintofen) 130561-48-7 single chemical entity Component is a metabolite of the substance 1-(-4’-chlorophenyl)-1,4-dihydro-5-(2’’-hydroxy-ethoxy)-4-oxo-cinnoline-3-carboxylate 1-(4-chlorophenyl)-5-(2-hydroxyethoxy)-4-oxo-1,4-dihydrocinnoline-3-carboxylic acid Sintofen metabolite (SC 3095) C17H13ClN2O5 OC(=O)C/2=N/N(c1ccc(Cl)cc1)c3cccc(OCCO)c3C\2=O InChI=1/C17H13ClN2O5/c18-10-4-6-11(7-5-10)20-12-2-1-3-13(25-9-8-21)14(12)16(22)15(19-20)17(23)24/h1-7,21H,8-9H2,(H,23,24) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: France Sintofen (revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen 14Dec2010 2010 doi:10.2903/j.efsa.2010.1931
+Sintofen (aka cintofen) 130561-48-7 single chemical entity Component is a metabolite of the substance 1-(-4’-chlorophenyl)-1,4-dihydro-5-(2’’-hydroxy-ethoxy)-4-oxo-cinnoline-3-carboxylate 1-(4-chlorophenyl)-5-(2-hydroxyethoxy)-4-oxo-1,4-dihydrocinnoline-3-carboxylic acid Sintofen metabolite (SC 3095) C17H13ClN2O5 OC(=O)C/2=N/N(c1ccc(Cl)cc1)c3cccc(OCCO)c3C\2=O InChI=1/C17H13ClN2O5/c18-10-4-6-11(7-5-10)20-12-2-1-3-13(25-9-8-21)14(12)16(22)15(19-20)17(23)24/h1-7,21H,8-9H2,(H,23,24) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: France Sintofen (revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen 14Dec2010 2010 doi:10.2903/j.efsa.2010.1931
+Triasulfuron 617-298-9 82097-50-5 single chemical entity Component is identical to the substance Triasulfuron 617-298-9 82097-50-5 1-[2-(2-chloroethoxy)phenylsulfonyl]-3-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)urea Triasulfuron C14H16ClN5O5S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2OCCCl InChI=1S/C14H16ClN5O5S/c1-9-16-12(19-14(17-9)24-2)18-13(21)20-26(22,23)11-6-4-3-5-10(11)25-8-7-15/h3-6H,7-8H2,1-2H3,(H2,16,17,18,19,20,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Denmark Triasulfuron (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron 09Jan2015 2015 doi:10.2903/j.efsa.2015.3958
+Triasulfuron 617-298-9 82097-50-5 single chemical entity Component is identical to the substance Triasulfuron 617-298-9 82097-50-5 1-[2-(2-chloroethoxy)phenylsulfonyl]-3-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)urea Triasulfuron C14H16ClN5O5S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2OCCCl InChI=1S/C14H16ClN5O5S/c1-9-16-12(19-14(17-9)24-2)18-13(21)20-26(22,23)11-6-4-3-5-10(11)25-8-7-15/h3-6H,7-8H2,1-2H3,(H2,16,17,18,19,20,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Denmark Triasulfuron (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron 09Jan2015 2015 doi:10.2903/j.efsa.2015.3958
+Triasulfuron 617-298-9 82097-50-5 single chemical entity Component is identical to the substance Triasulfuron 617-298-9 82097-50-5 1-[2-(2-chloroethoxy)phenylsulfonyl]-3-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)urea Triasulfuron C14H16ClN5O5S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2OCCCl InChI=1S/C14H16ClN5O5S/c1-9-16-12(19-14(17-9)24-2)18-13(21)20-26(22,23)11-6-4-3-5-10(11)25-8-7-15/h3-6H,7-8H2,1-2H3,(H2,16,17,18,19,20,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Denmark Triasulfuron (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron 09Jan2015 2015 doi:10.2903/j.efsa.2015.3958
+Triasulfuron 617-298-9 82097-50-5 single chemical entity Component is identical to the substance Triasulfuron 617-298-9 82097-50-5 1-[2-(2-chloroethoxy)phenylsulfonyl]-3-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)urea Triasulfuron C14H16ClN5O5S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2OCCCl InChI=1S/C14H16ClN5O5S/c1-9-16-12(19-14(17-9)24-2)18-13(21)20-26(22,23)11-6-4-3-5-10(11)25-8-7-15/h3-6H,7-8H2,1-2H3,(H2,16,17,18,19,20,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Denmark Triasulfuron (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron 09Jan2015 2015 doi:10.2903/j.efsa.2015.3958
+Triasulfuron 617-298-9 82097-50-5 single chemical entity Component is identical to the substance Triasulfuron 617-298-9 82097-50-5 1-[2-(2-chloroethoxy)phenylsulfonyl]-3-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)urea Triasulfuron C14H16ClN5O5S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2OCCCl InChI=1S/C14H16ClN5O5S/c1-9-16-12(19-14(17-9)24-2)18-13(21)20-26(22,23)11-6-4-3-5-10(11)25-8-7-15/h3-6H,7-8H2,1-2H3,(H2,16,17,18,19,20,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Denmark Triasulfuron (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron 09Jan2015 2015 doi:10.2903/j.efsa.2015.3958
+Triasulfuron 617-298-9 82097-50-5 single chemical entity Component is identical to the substance Triasulfuron 617-298-9 82097-50-5 1-[2-(2-chloroethoxy)phenylsulfonyl]-3-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)urea Triasulfuron C14H16ClN5O5S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2OCCCl InChI=1S/C14H16ClN5O5S/c1-9-16-12(19-14(17-9)24-2)18-13(21)20-26(22,23)11-6-4-3-5-10(11)25-8-7-15/h3-6H,7-8H2,1-2H3,(H2,16,17,18,19,20,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Denmark Triasulfuron (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron 09Jan2015 2015 doi:10.2903/j.efsa.2015.3958
+Triasulfuron 617-298-9 82097-50-5 single chemical entity Component is identical to the substance Triasulfuron 617-298-9 82097-50-5 1-[2-(2-chloroethoxy)phenylsulfonyl]-3-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)urea Triasulfuron C14H16ClN5O5S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2OCCCl InChI=1S/C14H16ClN5O5S/c1-9-16-12(19-14(17-9)24-2)18-13(21)20-26(22,23)11-6-4-3-5-10(11)25-8-7-15/h3-6H,7-8H2,1-2H3,(H2,16,17,18,19,20,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Denmark Triasulfuron (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron 09Jan2015 2015 doi:10.2903/j.efsa.2015.3958
+Triasulfuron 617-298-9 82097-50-5 single chemical entity Component is identical to the substance Triasulfuron 617-298-9 82097-50-5 1-[2-(2-chloroethoxy)phenylsulfonyl]-3-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)urea Triasulfuron C14H16ClN5O5S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2OCCCl InChI=1S/C14H16ClN5O5S/c1-9-16-12(19-14(17-9)24-2)18-13(21)20-26(22,23)11-6-4-3-5-10(11)25-8-7-15/h3-6H,7-8H2,1-2H3,(H2,16,17,18,19,20,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Denmark Triasulfuron (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron 09Jan2015 2015 doi:10.2903/j.efsa.2015.3958
+Triasulfuron 617-298-9 82097-50-5 single chemical entity Component is identical to the substance Triasulfuron 617-298-9 82097-50-5 1-[2-(2-chloroethoxy)phenylsulfonyl]-3-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)urea Triasulfuron C14H16ClN5O5S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2OCCCl InChI=1S/C14H16ClN5O5S/c1-9-16-12(19-14(17-9)24-2)18-13(21)20-26(22,23)11-6-4-3-5-10(11)25-8-7-15/h3-6H,7-8H2,1-2H3,(H2,16,17,18,19,20,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Denmark Triasulfuron (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron 09Jan2015 2015 doi:10.2903/j.efsa.2015.3958
+Triasulfuron 617-298-9 82097-50-5 single chemical entity Component is identical to the substance Triasulfuron 617-298-9 82097-50-5 1-[2-(2-chloroethoxy)phenylsulfonyl]-3-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)urea Triasulfuron C14H16ClN5O5S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2OCCCl InChI=1S/C14H16ClN5O5S/c1-9-16-12(19-14(17-9)24-2)18-13(21)20-26(22,23)11-6-4-3-5-10(11)25-8-7-15/h3-6H,7-8H2,1-2H3,(H2,16,17,18,19,20,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Denmark Triasulfuron (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron 09Jan2015 2015 doi:10.2903/j.efsa.2015.3958
+Triasulfuron 617-298-9 82097-50-5 single chemical entity Component is identical to the substance Triasulfuron 617-298-9 82097-50-5 1-[2-(2-chloroethoxy)phenylsulfonyl]-3-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)urea Triasulfuron C14H16ClN5O5S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2OCCCl InChI=1S/C14H16ClN5O5S/c1-9-16-12(19-14(17-9)24-2)18-13(21)20-26(22,23)11-6-4-3-5-10(11)25-8-7-15/h3-6H,7-8H2,1-2H3,(H2,16,17,18,19,20,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Denmark Triasulfuron (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron 09Jan2015 2015 doi:10.2903/j.efsa.2015.3958
+Triasulfuron 617-298-9 82097-50-5 single chemical entity Component is identical to the substance Triasulfuron 617-298-9 82097-50-5 1-[2-(2-chloroethoxy)phenylsulfonyl]-3-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)urea Triasulfuron C14H16ClN5O5S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2OCCCl InChI=1S/C14H16ClN5O5S/c1-9-16-12(19-14(17-9)24-2)18-13(21)20-26(22,23)11-6-4-3-5-10(11)25-8-7-15/h3-6H,7-8H2,1-2H3,(H2,16,17,18,19,20,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Denmark Triasulfuron (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron 09Jan2015 2015 doi:10.2903/j.efsa.2015.3958
+Triasulfuron 617-298-9 82097-50-5 single chemical entity Component is identical to the substance Triasulfuron 617-298-9 82097-50-5 1-[2-(2-chloroethoxy)phenylsulfonyl]-3-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)urea Triasulfuron C14H16ClN5O5S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2OCCCl InChI=1S/C14H16ClN5O5S/c1-9-16-12(19-14(17-9)24-2)18-13(21)20-26(22,23)11-6-4-3-5-10(11)25-8-7-15/h3-6H,7-8H2,1-2H3,(H2,16,17,18,19,20,21) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes without Positive RMS: France - CoRMS: Denmark Triasulfuron (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron 09Jan2015 2015 doi:10.2903/j.efsa.2015.3958
+Triasulfuron 617-298-9 82097-50-5 single chemical entity Component is identical to the substance Triasulfuron 617-298-9 82097-50-5 1-[2-(2-chloroethoxy)phenylsulfonyl]-3-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)urea Triasulfuron C14H16ClN5O5S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2OCCCl InChI=1S/C14H16ClN5O5S/c1-9-16-12(19-14(17-9)24-2)18-13(21)20-26(22,23)11-6-4-3-5-10(11)25-8-7-15/h3-6H,7-8H2,1-2H3,(H2,16,17,18,19,20,21) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes with Negative RMS: France - CoRMS: Denmark Triasulfuron (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron 09Jan2015 2015 doi:10.2903/j.efsa.2015.3958
+Triasulfuron 617-298-9 82097-50-5 single chemical entity Component is identical to the substance Triasulfuron 617-298-9 82097-50-5 1-[2-(2-chloroethoxy)phenylsulfonyl]-3-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)urea Triasulfuron C14H16ClN5O5S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2OCCCl InChI=1S/C14H16ClN5O5S/c1-9-16-12(19-14(17-9)24-2)18-13(21)20-26(22,23)11-6-4-3-5-10(11)25-8-7-15/h3-6H,7-8H2,1-2H3,(H2,16,17,18,19,20,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: France - CoRMS: Denmark Triasulfuron (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron 09Jan2015 2015 doi:10.2903/j.efsa.2015.3958
+Triasulfuron 617-298-9 82097-50-5 single chemical entity Component is identical to the substance Triasulfuron 617-298-9 82097-50-5 1-[2-(2-chloroethoxy)phenylsulfonyl]-3-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)urea Triasulfuron C14H16ClN5O5S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2OCCCl InChI=1S/C14H16ClN5O5S/c1-9-16-12(19-14(17-9)24-2)18-13(21)20-26(22,23)11-6-4-3-5-10(11)25-8-7-15/h3-6H,7-8H2,1-2H3,(H2,16,17,18,19,20,21) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: France - CoRMS: Denmark Triasulfuron (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron 09Jan2015 2015 doi:10.2903/j.efsa.2015.3958
+Triasulfuron 617-298-9 82097-50-5 single chemical entity Component is identical to the substance Triasulfuron 617-298-9 82097-50-5 1-[2-(2-chloroethoxy)phenylsulfonyl]-3-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)urea Triasulfuron C14H16ClN5O5S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2OCCCl InChI=1S/C14H16ClN5O5S/c1-9-16-12(19-14(17-9)24-2)18-13(21)20-26(22,23)11-6-4-3-5-10(11)25-8-7-15/h3-6H,7-8H2,1-2H3,(H2,16,17,18,19,20,21) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 7 Male oral: unspecified 48.0000000000 h yes not applicable Negative no evidence RMS: France - CoRMS: Denmark Triasulfuron (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron 09Jan2015 2015 doi:10.2903/j.efsa.2015.3958
+Triasulfuron 617-298-9 82097-50-5 single chemical entity Component is identical to the substance Triasulfuron 617-298-9 82097-50-5 1-[2-(2-chloroethoxy)phenylsulfonyl]-3-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)urea Triasulfuron C14H16ClN5O5S CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2OCCCl InChI=1S/C14H16ClN5O5S/c1-9-16-12(19-14(17-9)24-2)18-13(21)20-26(22,23)11-6-4-3-5-10(11)25-8-7-15/h3-6H,7-8H2,1-2H3,(H2,16,17,18,19,20,21) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 7 Male oral: unspecified 24.0000000000 h yes not applicable Negative no evidence RMS: France - CoRMS: Denmark Triasulfuron (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron 09Jan2015 2015 doi:10.2903/j.efsa.2015.3958
+Triasulfuron 617-298-9 82097-50-5 single chemical entity Component is a metabolite of the substance [(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamic acid [(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamic acid Not in list C6H9N5O5S Cc1nc(NC(=O)NS(=O)(=O)O)nc(OC)n1 InChI=1/C6H9N5O5S/c1-3-7-4(10-6(8-3)16-2)9-5(12)11-17(13,14)15/h1-2H3,(H,13,14,15)(H2,7,8,9,10,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Denmark Triasulfuron (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron 09Jan2015 2015 doi:10.2903/j.efsa.2015.3958
+Triasulfuron 617-298-9 82097-50-5 single chemical entity Component is a metabolite of the substance [(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamic acid [(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamic acid Not in list C6H9N5O5S Cc1nc(NC(=O)NS(=O)(=O)O)nc(OC)n1 InChI=1/C6H9N5O5S/c1-3-7-4(10-6(8-3)16-2)9-5(12)11-17(13,14)15/h1-2H3,(H,13,14,15)(H2,7,8,9,10,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Denmark Triasulfuron (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron 09Jan2015 2015 doi:10.2903/j.efsa.2015.3958
+Triasulfuron 617-298-9 82097-50-5 single chemical entity Component is a metabolite of the substance [(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamic acid [(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamic acid Not in list C6H9N5O5S Cc1nc(NC(=O)NS(=O)(=O)O)nc(OC)n1 InChI=1/C6H9N5O5S/c1-3-7-4(10-6(8-3)16-2)9-5(12)11-17(13,14)15/h1-2H3,(H,13,14,15)(H2,7,8,9,10,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Denmark Triasulfuron (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron 09Jan2015 2015 doi:10.2903/j.efsa.2015.3958
+Triasulfuron 617-298-9 82097-50-5 single chemical entity Component is a metabolite of the substance [(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamic acid [(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamic acid Not in list C6H9N5O5S Cc1nc(NC(=O)NS(=O)(=O)O)nc(OC)n1 InChI=1/C6H9N5O5S/c1-3-7-4(10-6(8-3)16-2)9-5(12)11-17(13,14)15/h1-2H3,(H,13,14,15)(H2,7,8,9,10,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Denmark Triasulfuron (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron 09Jan2015 2015 doi:10.2903/j.efsa.2015.3958
+Triasulfuron 617-298-9 82097-50-5 single chemical entity Component is a metabolite of the substance [(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamic acid [(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamic acid Not in list C6H9N5O5S Cc1nc(NC(=O)NS(=O)(=O)O)nc(OC)n1 InChI=1/C6H9N5O5S/c1-3-7-4(10-6(8-3)16-2)9-5(12)11-17(13,14)15/h1-2H3,(H,13,14,15)(H2,7,8,9,10,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Denmark Triasulfuron (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron 09Jan2015 2015 doi:10.2903/j.efsa.2015.3958
+Triasulfuron 617-298-9 82097-50-5 single chemical entity Component is a metabolite of the substance [(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamic acid [(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamic acid Not in list C6H9N5O5S Cc1nc(NC(=O)NS(=O)(=O)O)nc(OC)n1 InChI=1/C6H9N5O5S/c1-3-7-4(10-6(8-3)16-2)9-5(12)11-17(13,14)15/h1-2H3,(H,13,14,15)(H2,7,8,9,10,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Denmark Triasulfuron (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron 09Jan2015 2015 doi:10.2903/j.efsa.2015.3958
+Triasulfuron 617-298-9 82097-50-5 single chemical entity Component is a metabolite of the substance [(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamic acid [(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamic acid Not in list C6H9N5O5S Cc1nc(NC(=O)NS(=O)(=O)O)nc(OC)n1 InChI=1/C6H9N5O5S/c1-3-7-4(10-6(8-3)16-2)9-5(12)11-17(13,14)15/h1-2H3,(H,13,14,15)(H2,7,8,9,10,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Denmark Triasulfuron (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron 09Jan2015 2015 doi:10.2903/j.efsa.2015.3958
+Triasulfuron 617-298-9 82097-50-5 single chemical entity Component is a metabolite of the substance [(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamic acid [(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamic acid Not in list C6H9N5O5S Cc1nc(NC(=O)NS(=O)(=O)O)nc(OC)n1 InChI=1/C6H9N5O5S/c1-3-7-4(10-6(8-3)16-2)9-5(12)11-17(13,14)15/h1-2H3,(H,13,14,15)(H2,7,8,9,10,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Denmark Triasulfuron (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron 09Jan2015 2015 doi:10.2903/j.efsa.2015.3958
+Triasulfuron 617-298-9 82097-50-5 single chemical entity Component is a metabolite of the substance [(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamic acid [(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamic acid Not in list C6H9N5O5S Cc1nc(NC(=O)NS(=O)(=O)O)nc(OC)n1 InChI=1/C6H9N5O5S/c1-3-7-4(10-6(8-3)16-2)9-5(12)11-17(13,14)15/h1-2H3,(H,13,14,15)(H2,7,8,9,10,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Denmark Triasulfuron (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron 09Jan2015 2015 doi:10.2903/j.efsa.2015.3958
+Triasulfuron 617-298-9 82097-50-5 single chemical entity Component is a metabolite of the substance [(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamic acid [(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamic acid Not in list C6H9N5O5S Cc1nc(NC(=O)NS(=O)(=O)O)nc(OC)n1 InChI=1/C6H9N5O5S/c1-3-7-4(10-6(8-3)16-2)9-5(12)11-17(13,14)15/h1-2H3,(H,13,14,15)(H2,7,8,9,10,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Denmark Triasulfuron (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron 09Jan2015 2015 doi:10.2903/j.efsa.2015.3958
+Triasulfuron 617-298-9 82097-50-5 single chemical entity Component is a metabolite of the substance [(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamic acid [(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamic acid Not in list C6H9N5O5S Cc1nc(NC(=O)NS(=O)(=O)O)nc(OC)n1 InChI=1/C6H9N5O5S/c1-3-7-4(10-6(8-3)16-2)9-5(12)11-17(13,14)15/h1-2H3,(H,13,14,15)(H2,7,8,9,10,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Denmark Triasulfuron (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron 09Jan2015 2015 doi:10.2903/j.efsa.2015.3958
+Triasulfuron 617-298-9 82097-50-5 single chemical entity Component is a metabolite of the substance [(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamic acid [(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamic acid Not in list C6H9N5O5S Cc1nc(NC(=O)NS(=O)(=O)O)nc(OC)n1 InChI=1/C6H9N5O5S/c1-3-7-4(10-6(8-3)16-2)9-5(12)11-17(13,14)15/h1-2H3,(H,13,14,15)(H2,7,8,9,10,11,12) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Denmark Triasulfuron (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron 09Jan2015 2015 doi:10.2903/j.efsa.2015.3958
+Triasulfuron 617-298-9 82097-50-5 single chemical entity Component is a metabolite of the substance [(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamic acid [(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamic acid Not in list C6H9N5O5S Cc1nc(NC(=O)NS(=O)(=O)O)nc(OC)n1 InChI=1/C6H9N5O5S/c1-3-7-4(10-6(8-3)16-2)9-5(12)11-17(13,14)15/h1-2H3,(H,13,14,15)(H2,7,8,9,10,11,12) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: France - CoRMS: Denmark Triasulfuron (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron 09Jan2015 2015 doi:10.2903/j.efsa.2015.3958
+Triasulfuron 617-298-9 82097-50-5 single chemical entity Component is a metabolite of the substance [(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamic acid [(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamic acid Not in list C6H9N5O5S Cc1nc(NC(=O)NS(=O)(=O)O)nc(OC)n1 InChI=1/C6H9N5O5S/c1-3-7-4(10-6(8-3)16-2)9-5(12)11-17(13,14)15/h1-2H3,(H,13,14,15)(H2,7,8,9,10,11,12) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: France - CoRMS: Denmark Triasulfuron (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron 09Jan2015 2015 doi:10.2903/j.efsa.2015.3958
+Triasulfuron 617-298-9 82097-50-5 single chemical entity Component is a metabolite of the substance [(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamic acid [(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamic acid Not in list C6H9N5O5S Cc1nc(NC(=O)NS(=O)(=O)O)nc(OC)n1 InChI=1/C6H9N5O5S/c1-3-7-4(10-6(8-3)16-2)9-5(12)11-17(13,14)15/h1-2H3,(H,13,14,15)(H2,7,8,9,10,11,12) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Denmark Triasulfuron (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron 09Jan2015 2015 doi:10.2903/j.efsa.2015.3958
+Triasulfuron 617-298-9 82097-50-5 single chemical entity Component is a metabolite of the substance [(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamic acid [(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamic acid Not in list C6H9N5O5S Cc1nc(NC(=O)NS(=O)(=O)O)nc(OC)n1 InChI=1/C6H9N5O5S/c1-3-7-4(10-6(8-3)16-2)9-5(12)11-17(13,14)15/h1-2H3,(H,13,14,15)(H2,7,8,9,10,11,12) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Denmark Triasulfuron (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron 09Jan2015 2015 doi:10.2903/j.efsa.2015.3958
+Tralkoxydim 87820-88-0 single chemical entity Component is identical to the substance Tralkoxydim 87820-88-0 2-[1-(Ethoxyamino)propylidene]-5-(2,4,6-trimethylphenyl)cyclohexane-1, 3-dione Tralkoxydim C20H27NO3 CCC(=C1C(=O)CC(CC1=O)C2=C(C=C(C=C2C)C)C)NOCC InChI=1S/C20H27NO3/c1-6-16(21-24-7-2)20-17(22)10-15(11-18(20)23)19-13(4)8-12(3)9-14(19)5/h8-9,15,21H,6-7,10-11H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Tralkoxydim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim 28Jul2008 2008 doi:10.2903/j.efsa.2008.139r
+Tralkoxydim 87820-88-0 single chemical entity Component is identical to the substance Tralkoxydim 87820-88-0 2-[1-(Ethoxyamino)propylidene]-5-(2,4,6-trimethylphenyl)cyclohexane-1, 3-dione Tralkoxydim C20H27NO3 CCC(=C1C(=O)CC(CC1=O)C2=C(C=C(C=C2C)C)C)NOCC InChI=1S/C20H27NO3/c1-6-16(21-24-7-2)20-17(22)10-15(11-18(20)23)19-13(4)8-12(3)9-14(19)5/h8-9,15,21H,6-7,10-11H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Tralkoxydim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim 28Jul2008 2008 doi:10.2903/j.efsa.2008.139r
+Tralkoxydim 87820-88-0 single chemical entity Component is identical to the substance Tralkoxydim 87820-88-0 2-[1-(Ethoxyamino)propylidene]-5-(2,4,6-trimethylphenyl)cyclohexane-1, 3-dione Tralkoxydim C20H27NO3 CCC(=C1C(=O)CC(CC1=O)C2=C(C=C(C=C2C)C)C)NOCC InChI=1S/C20H27NO3/c1-6-16(21-24-7-2)20-17(22)10-15(11-18(20)23)19-13(4)8-12(3)9-14(19)5/h8-9,15,21H,6-7,10-11H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Tralkoxydim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim 28Jul2008 2008 doi:10.2903/j.efsa.2008.139r
+Tralkoxydim 87820-88-0 single chemical entity Component is identical to the substance Tralkoxydim 87820-88-0 2-[1-(Ethoxyamino)propylidene]-5-(2,4,6-trimethylphenyl)cyclohexane-1, 3-dione Tralkoxydim C20H27NO3 CCC(=C1C(=O)CC(CC1=O)C2=C(C=C(C=C2C)C)C)NOCC InChI=1S/C20H27NO3/c1-6-16(21-24-7-2)20-17(22)10-15(11-18(20)23)19-13(4)8-12(3)9-14(19)5/h8-9,15,21H,6-7,10-11H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Tralkoxydim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim 28Jul2008 2008 doi:10.2903/j.efsa.2008.139r
+Tralkoxydim 87820-88-0 single chemical entity Component is identical to the substance Tralkoxydim 87820-88-0 2-[1-(Ethoxyamino)propylidene]-5-(2,4,6-trimethylphenyl)cyclohexane-1, 3-dione Tralkoxydim C20H27NO3 CCC(=C1C(=O)CC(CC1=O)C2=C(C=C(C=C2C)C)C)NOCC InChI=1S/C20H27NO3/c1-6-16(21-24-7-2)20-17(22)10-15(11-18(20)23)19-13(4)8-12(3)9-14(19)5/h8-9,15,21H,6-7,10-11H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Tralkoxydim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim 28Jul2008 2008 doi:10.2903/j.efsa.2008.139r
+Tralkoxydim 87820-88-0 single chemical entity Component is identical to the substance Tralkoxydim 87820-88-0 2-[1-(Ethoxyamino)propylidene]-5-(2,4,6-trimethylphenyl)cyclohexane-1, 3-dione Tralkoxydim C20H27NO3 CCC(=C1C(=O)CC(CC1=O)C2=C(C=C(C=C2C)C)C)NOCC InChI=1S/C20H27NO3/c1-6-16(21-24-7-2)20-17(22)10-15(11-18(20)23)19-13(4)8-12(3)9-14(19)5/h8-9,15,21H,6-7,10-11H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Tralkoxydim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim 28Jul2008 2008 doi:10.2903/j.efsa.2008.139r
+Tralkoxydim 87820-88-0 single chemical entity Component is identical to the substance Tralkoxydim 87820-88-0 2-[1-(Ethoxyamino)propylidene]-5-(2,4,6-trimethylphenyl)cyclohexane-1, 3-dione Tralkoxydim C20H27NO3 CCC(=C1C(=O)CC(CC1=O)C2=C(C=C(C=C2C)C)C)NOCC InChI=1S/C20H27NO3/c1-6-16(21-24-7-2)20-17(22)10-15(11-18(20)23)19-13(4)8-12(3)9-14(19)5/h8-9,15,21H,6-7,10-11H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Tralkoxydim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim 28Jul2008 2008 doi:10.2903/j.efsa.2008.139r
+Tralkoxydim 87820-88-0 single chemical entity Component is identical to the substance Tralkoxydim 87820-88-0 2-[1-(Ethoxyamino)propylidene]-5-(2,4,6-trimethylphenyl)cyclohexane-1, 3-dione Tralkoxydim C20H27NO3 CCC(=C1C(=O)CC(CC1=O)C2=C(C=C(C=C2C)C)C)NOCC InChI=1S/C20H27NO3/c1-6-16(21-24-7-2)20-17(22)10-15(11-18(20)23)19-13(4)8-12(3)9-14(19)5/h8-9,15,21H,6-7,10-11H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Tralkoxydim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim 28Jul2008 2008 doi:10.2903/j.efsa.2008.139r
+Tralkoxydim 87820-88-0 single chemical entity Component is identical to the substance Tralkoxydim 87820-88-0 2-[1-(Ethoxyamino)propylidene]-5-(2,4,6-trimethylphenyl)cyclohexane-1, 3-dione Tralkoxydim C20H27NO3 CCC(=C1C(=O)CC(CC1=O)C2=C(C=C(C=C2C)C)C)NOCC InChI=1S/C20H27NO3/c1-6-16(21-24-7-2)20-17(22)10-15(11-18(20)23)19-13(4)8-12(3)9-14(19)5/h8-9,15,21H,6-7,10-11H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Tralkoxydim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim 28Jul2008 2008 doi:10.2903/j.efsa.2008.139r
+Tralkoxydim 87820-88-0 single chemical entity Component is identical to the substance Tralkoxydim 87820-88-0 2-[1-(Ethoxyamino)propylidene]-5-(2,4,6-trimethylphenyl)cyclohexane-1, 3-dione Tralkoxydim C20H27NO3 CCC(=C1C(=O)CC(CC1=O)C2=C(C=C(C=C2C)C)C)NOCC InChI=1S/C20H27NO3/c1-6-16(21-24-7-2)20-17(22)10-15(11-18(20)23)19-13(4)8-12(3)9-14(19)5/h8-9,15,21H,6-7,10-11H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Tralkoxydim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim 28Jul2008 2008 doi:10.2903/j.efsa.2008.139r
+Tralkoxydim 87820-88-0 single chemical entity Component is identical to the substance Tralkoxydim 87820-88-0 2-[1-(Ethoxyamino)propylidene]-5-(2,4,6-trimethylphenyl)cyclohexane-1, 3-dione Tralkoxydim C20H27NO3 CCC(=C1C(=O)CC(CC1=O)C2=C(C=C(C=C2C)C)C)NOCC InChI=1S/C20H27NO3/c1-6-16(21-24-7-2)20-17(22)10-15(11-18(20)23)19-13(4)8-12(3)9-14(19)5/h8-9,15,21H,6-7,10-11H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Tralkoxydim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim 28Jul2008 2008 doi:10.2903/j.efsa.2008.139r
+Tralkoxydim 87820-88-0 single chemical entity Component is identical to the substance Tralkoxydim 87820-88-0 2-[1-(Ethoxyamino)propylidene]-5-(2,4,6-trimethylphenyl)cyclohexane-1, 3-dione Tralkoxydim C20H27NO3 CCC(=C1C(=O)CC(CC1=O)C2=C(C=C(C=C2C)C)C)NOCC InChI=1S/C20H27NO3/c1-6-16(21-24-7-2)20-17(22)10-15(11-18(20)23)19-13(4)8-12(3)9-14(19)5/h8-9,15,21H,6-7,10-11H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Tralkoxydim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim 28Jul2008 2008 doi:10.2903/j.efsa.2008.139r
+Tralkoxydim 87820-88-0 single chemical entity Component is identical to the substance Tralkoxydim 87820-88-0 2-[1-(Ethoxyamino)propylidene]-5-(2,4,6-trimethylphenyl)cyclohexane-1, 3-dione Tralkoxydim C20H27NO3 CCC(=C1C(=O)CC(CC1=O)C2=C(C=C(C=C2C)C)C)NOCC InChI=1S/C20H27NO3/c1-6-16(21-24-7-2)20-17(22)10-15(11-18(20)23)19-13(4)8-12(3)9-14(19)5/h8-9,15,21H,6-7,10-11H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative small colonies RMS: The United Kingdom Tralkoxydim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim 28Jul2008 2008 doi:10.2903/j.efsa.2008.139r
+Tralkoxydim 87820-88-0 single chemical entity Component is identical to the substance Tralkoxydim 87820-88-0 2-[1-(Ethoxyamino)propylidene]-5-(2,4,6-trimethylphenyl)cyclohexane-1, 3-dione Tralkoxydim C20H27NO3 CCC(=C1C(=O)CC(CC1=O)C2=C(C=C(C=C2C)C)C)NOCC InChI=1S/C20H27NO3/c1-6-16(21-24-7-2)20-17(22)10-15(11-18(20)23)19-13(4)8-12(3)9-14(19)5/h8-9,15,21H,6-7,10-11H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative small colonies RMS: The United Kingdom Tralkoxydim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim 28Jul2008 2008 doi:10.2903/j.efsa.2008.139r
+Tralkoxydim 87820-88-0 single chemical entity Component is identical to the substance Tralkoxydim 87820-88-0 2-[1-(Ethoxyamino)propylidene]-5-(2,4,6-trimethylphenyl)cyclohexane-1, 3-dione Tralkoxydim C20H27NO3 CCC(=C1C(=O)CC(CC1=O)C2=C(C=C(C=C2C)C)C)NOCC InChI=1S/C20H27NO3/c1-6-16(21-24-7-2)20-17(22)10-15(11-18(20)23)19-13(4)8-12(3)9-14(19)5/h8-9,15,21H,6-7,10-11H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes without Ambiguous RMS: The United Kingdom Tralkoxydim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim 28Jul2008 2008 doi:10.2903/j.efsa.2008.139r
+Tralkoxydim 87820-88-0 single chemical entity Component is identical to the substance Tralkoxydim 87820-88-0 2-[1-(Ethoxyamino)propylidene]-5-(2,4,6-trimethylphenyl)cyclohexane-1, 3-dione Tralkoxydim C20H27NO3 CCC(=C1C(=O)CC(CC1=O)C2=C(C=C(C=C2C)C)C)NOCC InChI=1S/C20H27NO3/c1-6-16(21-24-7-2)20-17(22)10-15(11-18(20)23)19-13(4)8-12(3)9-14(19)5/h8-9,15,21H,6-7,10-11H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes with Negative RMS: The United Kingdom Tralkoxydim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim 28Jul2008 2008 doi:10.2903/j.efsa.2008.139r
+Tralkoxydim 87820-88-0 single chemical entity Component is identical to the substance Tralkoxydim 87820-88-0 2-[1-(Ethoxyamino)propylidene]-5-(2,4,6-trimethylphenyl)cyclohexane-1, 3-dione Tralkoxydim C20H27NO3 CCC(=C1C(=O)CC(CC1=O)C2=C(C=C(C=C2C)C)C)NOCC InChI=1S/C20H27NO3/c1-6-16(21-24-7-2)20-17(22)10-15(11-18(20)23)19-13(4)8-12(3)9-14(19)5/h8-9,15,21H,6-7,10-11H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) C57BL 10 Male/Female intraperitoneal 24.0000000000 h yes, concurrent vehicle not applicable Ambiguous indirect evidence-systemic toxicity RMS: The United Kingdom Tralkoxydim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim 28Jul2008 2008 doi:10.2903/j.efsa.2008.139r
+Tralkoxydim 87820-88-0 single chemical entity Component is identical to the substance Tralkoxydim 87820-88-0 2-[1-(Ethoxyamino)propylidene]-5-(2,4,6-trimethylphenyl)cyclohexane-1, 3-dione Tralkoxydim C20H27NO3 CCC(=C1C(=O)CC(CC1=O)C2=C(C=C(C=C2C)C)C)NOCC InChI=1S/C20H27NO3/c1-6-16(21-24-7-2)20-17(22)10-15(11-18(20)23)19-13(4)8-12(3)9-14(19)5/h8-9,15,21H,6-7,10-11H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) C57BL 10 Male/Female intraperitoneal 72.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: The United Kingdom Tralkoxydim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim 28Jul2008 2008 doi:10.2903/j.efsa.2008.139r
+Tralkoxydim 87820-88-0 single chemical entity Component is identical to the substance Tralkoxydim 87820-88-0 2-[1-(Ethoxyamino)propylidene]-5-(2,4,6-trimethylphenyl)cyclohexane-1, 3-dione Tralkoxydim C20H27NO3 CCC(=C1C(=O)CC(CC1=O)C2=C(C=C(C=C2C)C)C)NOCC InChI=1S/C20H27NO3/c1-6-16(21-24-7-2)20-17(22)10-15(11-18(20)23)19-13(4)8-12(3)9-14(19)5/h8-9,15,21H,6-7,10-11H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) C57BL 10 Male/Female intraperitoneal 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: The United Kingdom Tralkoxydim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim 28Jul2008 2008 doi:10.2903/j.efsa.2008.139r
+Tralkoxydim 87820-88-0 single chemical entity Component is identical to the substance Tralkoxydim 87820-88-0 2-[1-(Ethoxyamino)propylidene]-5-(2,4,6-trimethylphenyl)cyclohexane-1, 3-dione Tralkoxydim C20H27NO3 CCC(=C1C(=O)CC(CC1=O)C2=C(C=C(C=C2C)C)C)NOCC InChI=1S/C20H27NO3/c1-6-16(21-24-7-2)20-17(22)10-15(11-18(20)23)19-13(4)8-12(3)9-14(19)5/h8-9,15,21H,6-7,10-11H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo Equivalent or similar to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) Yes Acceptable Rat (as animal) Sprague-Dawley 5 Male oral: gavage 12.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Tralkoxydim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim 28Jul2008 2008 doi:10.2903/j.efsa.2008.139r
+Tralkoxydim 87820-88-0 single chemical entity Component is identical to the substance Tralkoxydim 87820-88-0 2-[1-(Ethoxyamino)propylidene]-5-(2,4,6-trimethylphenyl)cyclohexane-1, 3-dione Tralkoxydim C20H27NO3 CCC(=C1C(=O)CC(CC1=O)C2=C(C=C(C=C2C)C)C)NOCC InChI=1S/C20H27NO3/c1-6-16(21-24-7-2)20-17(22)10-15(11-18(20)23)19-13(4)8-12(3)9-14(19)5/h8-9,15,21H,6-7,10-11H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo Equivalent or similar to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) Yes Acceptable Rat (as animal) Sprague-Dawley 5 Male oral: gavage 4.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Tralkoxydim 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim 28Jul2008 2008 doi:10.2903/j.efsa.2008.139r
+Tralkoxydim 87820-88-0 single chemical entity Component is identical to the substance Tralkoxydim 87820-88-0 2-[1-(Ethoxyamino)propylidene]-5-(2,4,6-trimethylphenyl)cyclohexane-1, 3-dione Tralkoxydim C20H27NO3 CCC(=C1C(=O)CC(CC1=O)C2=C(C=C(C=C2C)C)C)NOCC InChI=1S/C20H27NO3/c1-6-16(21-24-7-2)20-17(22)10-15(11-18(20)23)19-13(4)8-12(3)9-14(19)5/h8-9,15,21H,6-7,10-11H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 5 Male oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: The United Kingdom Tralkoxydim (Addendum 1) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim 28Jul2008 2008 doi:10.2903/j.efsa.2008.139r
+Tralkoxydim 87820-88-0 single chemical entity Component is identical to the substance Tralkoxydim 87820-88-0 2-[1-(Ethoxyamino)propylidene]-5-(2,4,6-trimethylphenyl)cyclohexane-1, 3-dione Tralkoxydim C20H27NO3 CCC(=C1C(=O)CC(CC1=O)C2=C(C=C(C=C2C)C)C)NOCC InChI=1S/C20H27NO3/c1-6-16(21-24-7-2)20-17(22)10-15(11-18(20)23)19-13(4)8-12(3)9-14(19)5/h8-9,15,21H,6-7,10-11H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 5 Male oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: The United Kingdom Tralkoxydim (Addendum 1) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim 28Jul2008 2008 doi:10.2903/j.efsa.2008.139r
+Rimsulfuron 122931-48-0 single chemical entity Component is identical to the substance Rimsulfuron 122931-48-0 N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-3-(ethylsulfonyl)pyridine-2-sulfonamide Rimsulfuron C14H17N5O7S2 O=S(C1=NC=CC=C1S(CC)(=O)=O)(NC(NC2=NC(OC)=CC(OC)=N2)=O)=O InChI=1S/C14H17N5O7S2/c1-4-27(21,22)9-6-5-7-15-12(9)28(23,24)19-14(20)18-13-16-10(25-2)8-11(17-13)26-3/h5-8H,4H2,1-3H3,(H2,16,17,18,19,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany Rimsulfuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron 31Aug2005 2005 doi:10.2903/j.efsa.2005.45r
+Rimsulfuron 122931-48-0 single chemical entity Component is identical to the substance Rimsulfuron 122931-48-0 N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-3-(ethylsulfonyl)pyridine-2-sulfonamide Rimsulfuron C14H17N5O7S2 O=S(C1=NC=CC=C1S(CC)(=O)=O)(NC(NC2=NC(OC)=CC(OC)=N2)=O)=O InChI=1S/C14H17N5O7S2/c1-4-27(21,22)9-6-5-7-15-12(9)28(23,24)19-14(20)18-13-16-10(25-2)8-11(17-13)26-3/h5-8H,4H2,1-3H3,(H2,16,17,18,19,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany Rimsulfuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron 31Aug2005 2005 doi:10.2903/j.efsa.2005.45r
+Rimsulfuron 122931-48-0 single chemical entity Component is identical to the substance Rimsulfuron 122931-48-0 N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-3-(ethylsulfonyl)pyridine-2-sulfonamide Rimsulfuron C14H17N5O7S2 O=S(C1=NC=CC=C1S(CC)(=O)=O)(NC(NC2=NC(OC)=CC(OC)=N2)=O)=O InChI=1S/C14H17N5O7S2/c1-4-27(21,22)9-6-5-7-15-12(9)28(23,24)19-14(20)18-13-16-10(25-2)8-11(17-13)26-3/h5-8H,4H2,1-3H3,(H2,16,17,18,19,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany Rimsulfuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron 31Aug2005 2005 doi:10.2903/j.efsa.2005.45r
+Rimsulfuron 122931-48-0 single chemical entity Component is identical to the substance Rimsulfuron 122931-48-0 N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-3-(ethylsulfonyl)pyridine-2-sulfonamide Rimsulfuron C14H17N5O7S2 O=S(C1=NC=CC=C1S(CC)(=O)=O)(NC(NC2=NC(OC)=CC(OC)=N2)=O)=O InChI=1S/C14H17N5O7S2/c1-4-27(21,22)9-6-5-7-15-12(9)28(23,24)19-14(20)18-13-16-10(25-2)8-11(17-13)26-3/h5-8H,4H2,1-3H3,(H2,16,17,18,19,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany Rimsulfuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron 31Aug2005 2005 doi:10.2903/j.efsa.2005.45r
+Rimsulfuron 122931-48-0 single chemical entity Component is identical to the substance Rimsulfuron 122931-48-0 N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-3-(ethylsulfonyl)pyridine-2-sulfonamide Rimsulfuron C14H17N5O7S2 O=S(C1=NC=CC=C1S(CC)(=O)=O)(NC(NC2=NC(OC)=CC(OC)=N2)=O)=O InChI=1S/C14H17N5O7S2/c1-4-27(21,22)9-6-5-7-15-12(9)28(23,24)19-14(20)18-13-16-10(25-2)8-11(17-13)26-3/h5-8H,4H2,1-3H3,(H2,16,17,18,19,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle without Negative RMS: Germany Rimsulfuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron 31Aug2005 2005 doi:10.2903/j.efsa.2005.45r
+Rimsulfuron 122931-48-0 single chemical entity Component is identical to the substance Rimsulfuron 122931-48-0 N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-3-(ethylsulfonyl)pyridine-2-sulfonamide Rimsulfuron C14H17N5O7S2 O=S(C1=NC=CC=C1S(CC)(=O)=O)(NC(NC2=NC(OC)=CC(OC)=N2)=O)=O InChI=1S/C14H17N5O7S2/c1-4-27(21,22)9-6-5-7-15-12(9)28(23,24)19-14(20)18-13-16-10(25-2)8-11(17-13)26-3/h5-8H,4H2,1-3H3,(H2,16,17,18,19,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle with Negative RMS: Germany Rimsulfuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron 31Aug2005 2005 doi:10.2903/j.efsa.2005.45r
+Rimsulfuron 122931-48-0 single chemical entity Component is identical to the substance Rimsulfuron 122931-48-0 N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-3-(ethylsulfonyl)pyridine-2-sulfonamide Rimsulfuron C14H17N5O7S2 O=S(C1=NC=CC=C1S(CC)(=O)=O)(NC(NC2=NC(OC)=CC(OC)=N2)=O)=O InChI=1S/C14H17N5O7S2/c1-4-27(21,22)9-6-5-7-15-12(9)28(23,24)19-14(20)18-13-16-10(25-2)8-11(17-13)26-3/h5-8H,4H2,1-3H3,(H2,16,17,18,19,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany Rimsulfuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron 31Aug2005 2005 doi:10.2903/j.efsa.2005.45r
+Rimsulfuron 122931-48-0 single chemical entity Component is identical to the substance Rimsulfuron 122931-48-0 N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-3-(ethylsulfonyl)pyridine-2-sulfonamide Rimsulfuron C14H17N5O7S2 O=S(C1=NC=CC=C1S(CC)(=O)=O)(NC(NC2=NC(OC)=CC(OC)=N2)=O)=O InChI=1S/C14H17N5O7S2/c1-4-27(21,22)9-6-5-7-15-12(9)28(23,24)19-14(20)18-13-16-10(25-2)8-11(17-13)26-3/h5-8H,4H2,1-3H3,(H2,16,17,18,19,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany Rimsulfuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron 31Aug2005 2005 doi:10.2903/j.efsa.2005.45r
+Rimsulfuron 122931-48-0 single chemical entity Component is identical to the substance Rimsulfuron 122931-48-0 N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-3-(ethylsulfonyl)pyridine-2-sulfonamide Rimsulfuron C14H17N5O7S2 O=S(C1=NC=CC=C1S(CC)(=O)=O)(NC(NC2=NC(OC)=CC(OC)=N2)=O)=O InChI=1S/C14H17N5O7S2/c1-4-27(21,22)9-6-5-7-15-12(9)28(23,24)19-14(20)18-13-16-10(25-2)8-11(17-13)26-3/h5-8H,4H2,1-3H3,(H2,16,17,18,19,20) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Germany Rimsulfuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron 31Aug2005 2005 doi:10.2903/j.efsa.2005.45r
+Rimsulfuron 122931-48-0 single chemical entity Component is identical to the substance Rimsulfuron 122931-48-0 N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-3-(ethylsulfonyl)pyridine-2-sulfonamide Rimsulfuron C14H17N5O7S2 O=S(C1=NC=CC=C1S(CC)(=O)=O)(NC(NC2=NC(OC)=CC(OC)=N2)=O)=O InChI=1S/C14H17N5O7S2/c1-4-27(21,22)9-6-5-7-15-12(9)28(23,24)19-14(20)18-13-16-10(25-2)8-11(17-13)26-3/h5-8H,4H2,1-3H3,(H2,16,17,18,19,20) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Germany Rimsulfuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron 31Aug2005 2005 doi:10.2903/j.efsa.2005.45r
+Rimsulfuron 122931-48-0 single chemical entity Component is identical to the substance Rimsulfuron 122931-48-0 N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-3-(ethylsulfonyl)pyridine-2-sulfonamide Rimsulfuron C14H17N5O7S2 O=S(C1=NC=CC=C1S(CC)(=O)=O)(NC(NC2=NC(OC)=CC(OC)=N2)=O)=O InChI=1S/C14H17N5O7S2/c1-4-27(21,22)9-6-5-7-15-12(9)28(23,24)19-14(20)18-13-16-10(25-2)8-11(17-13)26-3/h5-8H,4H2,1-3H3,(H2,16,17,18,19,20) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: Germany Rimsulfuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron 31Aug2005 2005 doi:10.2903/j.efsa.2005.45r
+Rimsulfuron 122931-48-0 single chemical entity Component is identical to the substance Rimsulfuron 122931-48-0 N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-3-(ethylsulfonyl)pyridine-2-sulfonamide Rimsulfuron C14H17N5O7S2 O=S(C1=NC=CC=C1S(CC)(=O)=O)(NC(NC2=NC(OC)=CC(OC)=N2)=O)=O InChI=1S/C14H17N5O7S2/c1-4-27(21,22)9-6-5-7-15-12(9)28(23,24)19-14(20)18-13-16-10(25-2)8-11(17-13)26-3/h5-8H,4H2,1-3H3,(H2,16,17,18,19,20) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: Germany Rimsulfuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron 31Aug2005 2005 doi:10.2903/j.efsa.2005.45r
+Rimsulfuron 122931-48-0 single chemical entity Component is identical to the substance Rimsulfuron 122931-48-0 N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-3-(ethylsulfonyl)pyridine-2-sulfonamide Rimsulfuron C14H17N5O7S2 O=S(C1=NC=CC=C1S(CC)(=O)=O)(NC(NC2=NC(OC)=CC(OC)=N2)=O)=O InChI=1S/C14H17N5O7S2/c1-4-27(21,22)9-6-5-7-15-12(9)28(23,24)19-14(20)18-13-16-10(25-2)8-11(17-13)26-3/h5-8H,4H2,1-3H3,(H2,16,17,18,19,20) organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Germany Rimsulfuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron 31Aug2005 2005 doi:10.2903/j.efsa.2005.45r
+Rimsulfuron 122931-48-0 single chemical entity Component is identical to the substance Rimsulfuron 122931-48-0 N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-3-(ethylsulfonyl)pyridine-2-sulfonamide Rimsulfuron C14H17N5O7S2 O=S(C1=NC=CC=C1S(CC)(=O)=O)(NC(NC2=NC(OC)=CC(OC)=N2)=O)=O InChI=1S/C14H17N5O7S2/c1-4-27(21,22)9-6-5-7-15-12(9)28(23,24)19-14(20)18-13-16-10(25-2)8-11(17-13)26-3/h5-8H,4H2,1-3H3,(H2,16,17,18,19,20) organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle with Negative RMS: Germany Rimsulfuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron 31Aug2005 2005 doi:10.2903/j.efsa.2005.45r
+Rimsulfuron 122931-48-0 single chemical entity Component is identical to the substance Rimsulfuron 122931-48-0 N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-3-(ethylsulfonyl)pyridine-2-sulfonamide Rimsulfuron C14H17N5O7S2 O=S(C1=NC=CC=C1S(CC)(=O)=O)(NC(NC2=NC(OC)=CC(OC)=N2)=O)=O InChI=1S/C14H17N5O7S2/c1-4-27(21,22)9-6-5-7-15-12(9)28(23,24)19-14(20)18-13-16-10(25-2)8-11(17-13)26-3/h5-8H,4H2,1-3H3,(H2,16,17,18,19,20) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Germany Rimsulfuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron 31Aug2005 2005 doi:10.2903/j.efsa.2005.45r
+Rimsulfuron 122931-48-0 single chemical entity Component is identical to the substance Rimsulfuron 122931-48-0 N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-3-(ethylsulfonyl)pyridine-2-sulfonamide Rimsulfuron C14H17N5O7S2 O=S(C1=NC=CC=C1S(CC)(=O)=O)(NC(NC2=NC(OC)=CC(OC)=N2)=O)=O InChI=1S/C14H17N5O7S2/c1-4-27(21,22)9-6-5-7-15-12(9)28(23,24)19-14(20)18-13-16-10(25-2)8-11(17-13)26-3/h5-8H,4H2,1-3H3,(H2,16,17,18,19,20) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Germany Rimsulfuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron 31Aug2005 2005 doi:10.2903/j.efsa.2005.45r
+Rimsulfuron 122931-48-0 single chemical entity Component is identical to the substance Rimsulfuron 122931-48-0 N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-3-(ethylsulfonyl)pyridine-2-sulfonamide Rimsulfuron C14H17N5O7S2 O=S(C1=NC=CC=C1S(CC)(=O)=O)(NC(NC2=NC(OC)=CC(OC)=N2)=O)=O InChI=1S/C14H17N5O7S2/c1-4-27(21,22)9-6-5-7-15-12(9)28(23,24)19-14(20)18-13-16-10(25-2)8-11(17-13)26-3/h5-8H,4H2,1-3H3,(H2,16,17,18,19,20) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 72.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Germany Rimsulfuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron 31Aug2005 2005 doi:10.2903/j.efsa.2005.45r
+Sodium silver thiosulfate single chemical entity Component is identical to the substance Sodium silver thiosulfate (in solution with a ratio of at least 1 to 8 silver to thiosulfate ions) Not in list inorganic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Silver thiosulphate 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sodium silver thiosulfate (in solution with a ratio of at least 1 to 8 silver to thiosulfate ions). 03Oct2013 2013 doi:10.2903/j.efsa.2013.3136
+Sodium silver thiosulfate single chemical entity Component is identical to the substance Sodium silver thiosulfate (in solution with a ratio of at least 1 to 8 silver to thiosulfate ions) Not in list inorganic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Silver thiosulphate 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sodium silver thiosulfate (in solution with a ratio of at least 1 to 8 silver to thiosulfate ions). 03Oct2013 2013 doi:10.2903/j.efsa.2013.3136
+Sodium silver thiosulfate single chemical entity Component is identical to the substance Sodium silver thiosulfate (in solution with a ratio of at least 1 to 8 silver to thiosulfate ions) Not in list inorganic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Silver thiosulphate 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sodium silver thiosulfate (in solution with a ratio of at least 1 to 8 silver to thiosulfate ions). 03Oct2013 2013 doi:10.2903/j.efsa.2013.3136
+Sodium silver thiosulfate single chemical entity Component is identical to the substance Sodium silver thiosulfate (in solution with a ratio of at least 1 to 8 silver to thiosulfate ions) Not in list inorganic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Silver thiosulphate 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sodium silver thiosulfate (in solution with a ratio of at least 1 to 8 silver to thiosulfate ions). 03Oct2013 2013 doi:10.2903/j.efsa.2013.3136
+Sodium silver thiosulfate single chemical entity Component is identical to the substance Sodium silver thiosulfate (in solution with a ratio of at least 1 to 8 silver to thiosulfate ions) Not in list inorganic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Silver thiosulphate 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sodium silver thiosulfate (in solution with a ratio of at least 1 to 8 silver to thiosulfate ions). 03Oct2013 2013 doi:10.2903/j.efsa.2013.3136
+Sodium silver thiosulfate single chemical entity Component is identical to the substance Sodium silver thiosulfate (in solution with a ratio of at least 1 to 8 silver to thiosulfate ions) Not in list inorganic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Silver thiosulphate 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sodium silver thiosulfate (in solution with a ratio of at least 1 to 8 silver to thiosulfate ions). 03Oct2013 2013 doi:10.2903/j.efsa.2013.3136
+Sodium silver thiosulfate single chemical entity Component is identical to the substance Sodium silver thiosulfate (in solution with a ratio of at least 1 to 8 silver to thiosulfate ions) Not in list inorganic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Silver thiosulphate 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sodium silver thiosulfate (in solution with a ratio of at least 1 to 8 silver to thiosulfate ions). 03Oct2013 2013 doi:10.2903/j.efsa.2013.3136
+Sodium silver thiosulfate single chemical entity Component is identical to the substance Sodium silver thiosulfate (in solution with a ratio of at least 1 to 8 silver to thiosulfate ions) Not in list inorganic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Silver thiosulphate 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sodium silver thiosulfate (in solution with a ratio of at least 1 to 8 silver to thiosulfate ions). 03Oct2013 2013 doi:10.2903/j.efsa.2013.3136
+Sodium silver thiosulfate single chemical entity Component is identical to the substance Sodium silver thiosulfate (in solution with a ratio of at least 1 to 8 silver to thiosulfate ions) Not in list inorganic no structure gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Positive small colonies RMS: The Netherlands Silver thiosulphate 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sodium silver thiosulfate (in solution with a ratio of at least 1 to 8 silver to thiosulfate ions). 03Oct2013 2013 doi:10.2903/j.efsa.2013.3136
+Sodium silver thiosulfate single chemical entity Component is identical to the substance Sodium silver thiosulfate (in solution with a ratio of at least 1 to 8 silver to thiosulfate ions) Not in list inorganic no structure gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Positive large colonies RMS: The Netherlands Silver thiosulphate 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sodium silver thiosulfate (in solution with a ratio of at least 1 to 8 silver to thiosulfate ions). 03Oct2013 2013 doi:10.2903/j.efsa.2013.3136
+Sodium silver thiosulfate single chemical entity Component is identical to the substance Sodium silver thiosulfate (in solution with a ratio of at least 1 to 8 silver to thiosulfate ions) Not in list inorganic no structure gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Positive small colonies RMS: The Netherlands Silver thiosulphate 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sodium silver thiosulfate (in solution with a ratio of at least 1 to 8 silver to thiosulfate ions). 03Oct2013 2013 doi:10.2903/j.efsa.2013.3136
+Sodium silver thiosulfate single chemical entity Component is identical to the substance Sodium silver thiosulfate (in solution with a ratio of at least 1 to 8 silver to thiosulfate ions) Not in list inorganic no structure gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Positive large colonies RMS: The Netherlands Silver thiosulphate 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sodium silver thiosulfate (in solution with a ratio of at least 1 to 8 silver to thiosulfate ions). 03Oct2013 2013 doi:10.2903/j.efsa.2013.3136
+Sodium silver thiosulfate single chemical entity Component is identical to the substance Sodium silver thiosulfate (in solution with a ratio of at least 1 to 8 silver to thiosulfate ions) Not in list inorganic no structure chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: The Netherlands Silver thiosulphate 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sodium silver thiosulfate (in solution with a ratio of at least 1 to 8 silver to thiosulfate ions). 03Oct2013 2013 doi:10.2903/j.efsa.2013.3136
+Sodium silver thiosulfate single chemical entity Component is identical to the substance Sodium silver thiosulfate (in solution with a ratio of at least 1 to 8 silver to thiosulfate ions) Not in list inorganic no structure chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: The Netherlands Silver thiosulphate 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sodium silver thiosulfate (in solution with a ratio of at least 1 to 8 silver to thiosulfate ions). 03Oct2013 2013 doi:10.2903/j.efsa.2013.3136
+Sodium silver thiosulfate single chemical entity Component is identical to the substance Sodium silver thiosulfate (in solution with a ratio of at least 1 to 8 silver to thiosulfate ions) Not in list inorganic no structure DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Wistar 6 Male oral: gavage 3.0000000000 month yes not applicable Negative RMS: The Netherlands Silver thiosulphate 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sodium silver thiosulfate (in solution with a ratio of at least 1 to 8 silver to thiosulfate ions). 03Oct2013 2013 doi:10.2903/j.efsa.2013.3136
+Rimsulfuron 122931-48-0 single chemical entity Component is a metabolite of the substance (3-(ethylsulfonyl)-2-pyridinesulfonamide 3-(ethylsulfonyl)pyridine-2-sulfonamide Not in list C7H10N2O4S2 O=S(N)(=O)c1ncccc1S(=O)(=O)CC InChI=1/C7H10N2O4S2/c1-2-14(10,11)6-4-3-5-9-7(6)15(8,12)13/h3-5H,2H2,1H3,(H2,8,12,13) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Germany Rimsulfuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron 31Aug2005 2005 doi:10.2903/j.efsa.2005.45r
+Rimsulfuron 122931-48-0 single chemical entity Component is a metabolite of the substance (3-(ethylsulfonyl)-2-pyridinesulfonamide 3-(ethylsulfonyl)pyridine-2-sulfonamide Not in list C7H10N2O4S2 O=S(N)(=O)c1ncccc1S(=O)(=O)CC InChI=1/C7H10N2O4S2/c1-2-14(10,11)6-4-3-5-9-7(6)15(8,12)13/h3-5H,2H2,1H3,(H2,8,12,13) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Germany Rimsulfuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron 31Aug2005 2005 doi:10.2903/j.efsa.2005.45r
+Rimsulfuron 122931-48-0 single chemical entity Component is a metabolite of the substance (3-(ethylsulfonyl)-2-pyridinesulfonamide 3-(ethylsulfonyl)pyridine-2-sulfonamide Not in list C7H10N2O4S2 O=S(N)(=O)c1ncccc1S(=O)(=O)CC InChI=1/C7H10N2O4S2/c1-2-14(10,11)6-4-3-5-9-7(6)15(8,12)13/h3-5H,2H2,1H3,(H2,8,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany Rimsulfuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron 31Aug2005 2005 doi:10.2903/j.efsa.2005.45r
+Rimsulfuron 122931-48-0 single chemical entity Component is a metabolite of the substance (3-(ethylsulfonyl)-2-pyridinesulfonamide 3-(ethylsulfonyl)pyridine-2-sulfonamide Not in list C7H10N2O4S2 O=S(N)(=O)c1ncccc1S(=O)(=O)CC InChI=1/C7H10N2O4S2/c1-2-14(10,11)6-4-3-5-9-7(6)15(8,12)13/h3-5H,2H2,1H3,(H2,8,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany Rimsulfuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron 31Aug2005 2005 doi:10.2903/j.efsa.2005.45r
+Rimsulfuron 122931-48-0 single chemical entity Component is a metabolite of the substance (3-(ethylsulfonyl)-2-pyridinesulfonamide 3-(ethylsulfonyl)pyridine-2-sulfonamide Not in list C7H10N2O4S2 O=S(N)(=O)c1ncccc1S(=O)(=O)CC InChI=1/C7H10N2O4S2/c1-2-14(10,11)6-4-3-5-9-7(6)15(8,12)13/h3-5H,2H2,1H3,(H2,8,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle without Negative RMS: Germany Rimsulfuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron 31Aug2005 2005 doi:10.2903/j.efsa.2005.45r
+Rimsulfuron 122931-48-0 single chemical entity Component is a metabolite of the substance (3-(ethylsulfonyl)-2-pyridinesulfonamide 3-(ethylsulfonyl)pyridine-2-sulfonamide Not in list C7H10N2O4S2 O=S(N)(=O)c1ncccc1S(=O)(=O)CC InChI=1/C7H10N2O4S2/c1-2-14(10,11)6-4-3-5-9-7(6)15(8,12)13/h3-5H,2H2,1H3,(H2,8,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany Rimsulfuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron 31Aug2005 2005 doi:10.2903/j.efsa.2005.45r
+Rimsulfuron 122931-48-0 single chemical entity Component is a metabolite of the substance (3-(ethylsulfonyl)-2-pyridinesulfonamide 3-(ethylsulfonyl)pyridine-2-sulfonamide Not in list C7H10N2O4S2 O=S(N)(=O)c1ncccc1S(=O)(=O)CC InChI=1/C7H10N2O4S2/c1-2-14(10,11)6-4-3-5-9-7(6)15(8,12)13/h3-5H,2H2,1H3,(H2,8,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle with Negative RMS: Germany Rimsulfuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron 31Aug2005 2005 doi:10.2903/j.efsa.2005.45r
+Rimsulfuron 122931-48-0 single chemical entity Component is a metabolite of the substance (3-(ethylsulfonyl)-2-pyridinesulfonamide 3-(ethylsulfonyl)pyridine-2-sulfonamide Not in list C7H10N2O4S2 O=S(N)(=O)c1ncccc1S(=O)(=O)CC InChI=1/C7H10N2O4S2/c1-2-14(10,11)6-4-3-5-9-7(6)15(8,12)13/h3-5H,2H2,1H3,(H2,8,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany Rimsulfuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron 31Aug2005 2005 doi:10.2903/j.efsa.2005.45r
+Rimsulfuron 122931-48-0 single chemical entity Component is a metabolite of the substance (3-(ethylsulfonyl)-2-pyridinesulfonamide 3-(ethylsulfonyl)pyridine-2-sulfonamide Not in list C7H10N2O4S2 O=S(N)(=O)c1ncccc1S(=O)(=O)CC InChI=1/C7H10N2O4S2/c1-2-14(10,11)6-4-3-5-9-7(6)15(8,12)13/h3-5H,2H2,1H3,(H2,8,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany Rimsulfuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron 31Aug2005 2005 doi:10.2903/j.efsa.2005.45r
+Rimsulfuron 122931-48-0 single chemical entity Component is a metabolite of the substance (3-(ethylsulfonyl)-2-pyridinesulfonamide 3-(ethylsulfonyl)pyridine-2-sulfonamide Not in list C7H10N2O4S2 O=S(N)(=O)c1ncccc1S(=O)(=O)CC InChI=1/C7H10N2O4S2/c1-2-14(10,11)6-4-3-5-9-7(6)15(8,12)13/h3-5H,2H2,1H3,(H2,8,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany Rimsulfuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron 31Aug2005 2005 doi:10.2903/j.efsa.2005.45r
+Rimsulfuron 122931-48-0 single chemical entity Component is a metabolite of the substance (N-(4,6-dimethoxy-2-pyrimidinyl)-N-((3-ethylsulfonyl)-2-pyridinyl)urea) 1-(4,6-dimethoxypyrimidin-2-yl)-1-[3-(ethylsulfonyl)pyridin-2-yl]urea Not in list C14H17N5O5S O=C(N)N(c1nc(cc(OC)n1)OC)c2ncccc2S(=O)(=O)CC InChI=1/C14H17N5O5S/c1-4-25(21,22)9-6-5-7-16-12(9)19(13(15)20)14-17-10(23-2)8-11(18-14)24-3/h5-8H,4H2,1-3H3,(H2,15,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle with Negative RMS: Germany Rimsulfuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron 31Aug2005 2005 doi:10.2903/j.efsa.2005.45r
+Rimsulfuron 122931-48-0 single chemical entity Component is a metabolite of the substance (N-(4,6-dimethoxy-2-pyrimidinyl)-N-((3-ethylsulfonyl)-2-pyridinyl)urea) 1-(4,6-dimethoxypyrimidin-2-yl)-1-[3-(ethylsulfonyl)pyridin-2-yl]urea Not in list C14H17N5O5S O=C(N)N(c1nc(cc(OC)n1)OC)c2ncccc2S(=O)(=O)CC InChI=1/C14H17N5O5S/c1-4-25(21,22)9-6-5-7-16-12(9)19(13(15)20)14-17-10(23-2)8-11(18-14)24-3/h5-8H,4H2,1-3H3,(H2,15,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany Rimsulfuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron 31Aug2005 2005 doi:10.2903/j.efsa.2005.45r
+Rimsulfuron 122931-48-0 single chemical entity Component is a metabolite of the substance (N-(4,6-dimethoxy-2-pyrimidinyl)-N-((3-ethylsulfonyl)-2-pyridinyl)urea) 1-(4,6-dimethoxypyrimidin-2-yl)-1-[3-(ethylsulfonyl)pyridin-2-yl]urea Not in list C14H17N5O5S O=C(N)N(c1nc(cc(OC)n1)OC)c2ncccc2S(=O)(=O)CC InChI=1/C14H17N5O5S/c1-4-25(21,22)9-6-5-7-16-12(9)19(13(15)20)14-17-10(23-2)8-11(18-14)24-3/h5-8H,4H2,1-3H3,(H2,15,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany Rimsulfuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron 31Aug2005 2005 doi:10.2903/j.efsa.2005.45r
+Rimsulfuron 122931-48-0 single chemical entity Component is a metabolite of the substance (N-(4,6-dimethoxy-2-pyrimidinyl)-N-((3-ethylsulfonyl)-2-pyridinyl)urea) 1-(4,6-dimethoxypyrimidin-2-yl)-1-[3-(ethylsulfonyl)pyridin-2-yl]urea Not in list C14H17N5O5S O=C(N)N(c1nc(cc(OC)n1)OC)c2ncccc2S(=O)(=O)CC InChI=1/C14H17N5O5S/c1-4-25(21,22)9-6-5-7-16-12(9)19(13(15)20)14-17-10(23-2)8-11(18-14)24-3/h5-8H,4H2,1-3H3,(H2,15,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle without Negative RMS: Germany Rimsulfuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron 31Aug2005 2005 doi:10.2903/j.efsa.2005.45r
+Rimsulfuron 122931-48-0 single chemical entity Component is a metabolite of the substance (N-(4,6-dimethoxy-2-pyrimidinyl)-N-((3-ethylsulfonyl)-2-pyridinyl)urea) 1-(4,6-dimethoxypyrimidin-2-yl)-1-[3-(ethylsulfonyl)pyridin-2-yl]urea Not in list C14H17N5O5S O=C(N)N(c1nc(cc(OC)n1)OC)c2ncccc2S(=O)(=O)CC InChI=1/C14H17N5O5S/c1-4-25(21,22)9-6-5-7-16-12(9)19(13(15)20)14-17-10(23-2)8-11(18-14)24-3/h5-8H,4H2,1-3H3,(H2,15,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany Rimsulfuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron 31Aug2005 2005 doi:10.2903/j.efsa.2005.45r
+Rimsulfuron 122931-48-0 single chemical entity Component is a metabolite of the substance (N-(4,6-dimethoxy-2-pyrimidinyl)-N-((3-ethylsulfonyl)-2-pyridinyl)urea) 1-(4,6-dimethoxypyrimidin-2-yl)-1-[3-(ethylsulfonyl)pyridin-2-yl]urea Not in list C14H17N5O5S O=C(N)N(c1nc(cc(OC)n1)OC)c2ncccc2S(=O)(=O)CC InChI=1/C14H17N5O5S/c1-4-25(21,22)9-6-5-7-16-12(9)19(13(15)20)14-17-10(23-2)8-11(18-14)24-3/h5-8H,4H2,1-3H3,(H2,15,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany Rimsulfuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron 31Aug2005 2005 doi:10.2903/j.efsa.2005.45r
+Rimsulfuron 122931-48-0 single chemical entity Component is a metabolite of the substance (N-(4,6-dimethoxy-2-pyrimidinyl)-N-((3-ethylsulfonyl)-2-pyridinyl)urea) 1-(4,6-dimethoxypyrimidin-2-yl)-1-[3-(ethylsulfonyl)pyridin-2-yl]urea Not in list C14H17N5O5S O=C(N)N(c1nc(cc(OC)n1)OC)c2ncccc2S(=O)(=O)CC InChI=1/C14H17N5O5S/c1-4-25(21,22)9-6-5-7-16-12(9)19(13(15)20)14-17-10(23-2)8-11(18-14)24-3/h5-8H,4H2,1-3H3,(H2,15,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany Rimsulfuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron 31Aug2005 2005 doi:10.2903/j.efsa.2005.45r
+Rimsulfuron 122931-48-0 single chemical entity Component is a metabolite of the substance (N-(4,6-dimethoxy-2-pyrimidinyl)-N-((3-ethylsulfonyl)-2-pyridinyl)urea) 1-(4,6-dimethoxypyrimidin-2-yl)-1-[3-(ethylsulfonyl)pyridin-2-yl]urea Not in list C14H17N5O5S O=C(N)N(c1nc(cc(OC)n1)OC)c2ncccc2S(=O)(=O)CC InChI=1/C14H17N5O5S/c1-4-25(21,22)9-6-5-7-16-12(9)19(13(15)20)14-17-10(23-2)8-11(18-14)24-3/h5-8H,4H2,1-3H3,(H2,15,20) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany Rimsulfuron 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron 31Aug2005 2005 doi:10.2903/j.efsa.2005.45r
+Rimsulfuron 122931-48-0 single chemical entity Component is a metabolite of the substance (N-(4,6-dimethoxy-2-pyrimidinyl)-N-((3-ethylsulfonyl)-2-pyridinyl)urea) 1-(4,6-dimethoxypyrimidin-2-yl)-1-[3-(ethylsulfonyl)pyridin-2-yl]urea Not in list C14H17N5O5S O=C(N)N(c1nc(cc(OC)n1)OC)c2ncccc2S(=O)(=O)CC InChI=1/C14H17N5O5S/c1-4-25(21,22)9-6-5-7-16-12(9)19(13(15)20)14-17-10(23-2)8-11(18-14)24-3/h5-8H,4H2,1-3H3,(H2,15,20) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Germany Rimsulfuron (Final addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron 31Aug2005 2005 doi:10.2903/j.efsa.2005.45r
+Rimsulfuron 122931-48-0 single chemical entity Component is a metabolite of the substance (N-(4,6-dimethoxy-2-pyrimidinyl)-N-((3-ethylsulfonyl)-2-pyridinyl)urea) 1-(4,6-dimethoxypyrimidin-2-yl)-1-[3-(ethylsulfonyl)pyridin-2-yl]urea Not in list C14H17N5O5S O=C(N)N(c1nc(cc(OC)n1)OC)c2ncccc2S(=O)(=O)CC InChI=1/C14H17N5O5S/c1-4-25(21,22)9-6-5-7-16-12(9)19(13(15)20)14-17-10(23-2)8-11(18-14)24-3/h5-8H,4H2,1-3H3,(H2,15,20) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Germany Rimsulfuron (Final addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron 31Aug2005 2005 doi:10.2903/j.efsa.2005.45r
+Rimsulfuron 122931-48-0 single chemical entity Component is a metabolite of the substance (N-(4,6-dimethoxy-2-pyrimidinyl)-N-((3-ethylsulfonyl)-2-pyridinyl)urea) 1-(4,6-dimethoxypyrimidin-2-yl)-1-[3-(ethylsulfonyl)pyridin-2-yl]urea Not in list C14H17N5O5S O=C(N)N(c1nc(cc(OC)n1)OC)c2ncccc2S(=O)(=O)CC InChI=1/C14H17N5O5S/c1-4-25(21,22)9-6-5-7-16-12(9)19(13(15)20)14-17-10(23-2)8-11(18-14)24-3/h5-8H,4H2,1-3H3,(H2,15,20) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Germany Rimsulfuron (Final addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron 31Aug2005 2005 doi:10.2903/j.efsa.2005.45r
+Rimsulfuron 122931-48-0 single chemical entity Component is a metabolite of the substance (N-(4,6-dimethoxy-2-pyrimidinyl)-N-((3-ethylsulfonyl)-2-pyridinyl)urea) 1-(4,6-dimethoxypyrimidin-2-yl)-1-[3-(ethylsulfonyl)pyridin-2-yl]urea Not in list C14H17N5O5S O=C(N)N(c1nc(cc(OC)n1)OC)c2ncccc2S(=O)(=O)CC InChI=1/C14H17N5O5S/c1-4-25(21,22)9-6-5-7-16-12(9)19(13(15)20)14-17-10(23-2)8-11(18-14)24-3/h5-8H,4H2,1-3H3,(H2,15,20) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Germany Rimsulfuron (Final addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron 31Aug2005 2005 doi:10.2903/j.efsa.2005.45r
+Spinetoram 935545-74-7 mixture or formulation Component is identical to the substance Spinetoram 935545-74-7 (3aR,5aR,9S,13S,14R,16aS,16bR)-13-{[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy}-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-a-L-mannopyranoside Spinetoram (XDE-175) C42H69NO10 CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@@H]3[C@H](C2CC(=O)O1)CC[C@H]4[C@H]3CC(C4)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OCC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C InChI=1S/C42H69NO10/c1-10-27-13-12-14-35(53-37-18-17-34(43(6)7)24(4)49-37)23(3)38(45)33-21-31-29(32(33)22-36(44)51-27)16-15-26-19-28(20-30(26)31)52-42-41(47-9)40(48-11-2)39(46-8)25(5)50-42/h21,23-32,34-35,37,39-42H,10-20,22H2,1-9H3/t23-,24-,25+,26-,27+,28?,29-,30-,31-,32?,34+,35+,37+,39+,40-,41-,42+/m1/s1 organic representative compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom XDE-175 (spinetoram) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram. 08May2013 2013 doi:10.2903/j.efsa.2013.3220
+Spinetoram 935545-74-7 mixture or formulation Component is identical to the substance Spinetoram 935545-74-7 (3aR,5aR,9S,13S,14R,16aS,16bR)-13-{[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy}-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-a-L-mannopyranoside Spinetoram (XDE-175) C42H69NO10 CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@@H]3[C@H](C2CC(=O)O1)CC[C@H]4[C@H]3CC(C4)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OCC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C InChI=1S/C42H69NO10/c1-10-27-13-12-14-35(53-37-18-17-34(43(6)7)24(4)49-37)23(3)38(45)33-21-31-29(32(33)22-36(44)51-27)16-15-26-19-28(20-30(26)31)52-42-41(47-9)40(48-11-2)39(46-8)25(5)50-42/h21,23-32,34-35,37,39-42H,10-20,22H2,1-9H3/t23-,24-,25+,26-,27+,28?,29-,30-,31-,32?,34+,35+,37+,39+,40-,41-,42+/m1/s1 organic representative compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom XDE-175 (spinetoram) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram. 08May2013 2013 doi:10.2903/j.efsa.2013.3220
+Spinetoram 935545-74-7 mixture or formulation Component is identical to the substance Spinetoram 935545-74-7 (3aR,5aR,9S,13S,14R,16aS,16bR)-13-{[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy}-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-a-L-mannopyranoside Spinetoram (XDE-175) C42H69NO10 CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@@H]3[C@H](C2CC(=O)O1)CC[C@H]4[C@H]3CC(C4)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OCC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C InChI=1S/C42H69NO10/c1-10-27-13-12-14-35(53-37-18-17-34(43(6)7)24(4)49-37)23(3)38(45)33-21-31-29(32(33)22-36(44)51-27)16-15-26-19-28(20-30(26)31)52-42-41(47-9)40(48-11-2)39(46-8)25(5)50-42/h21,23-32,34-35,37,39-42H,10-20,22H2,1-9H3/t23-,24-,25+,26-,27+,28?,29-,30-,31-,32?,34+,35+,37+,39+,40-,41-,42+/m1/s1 organic representative compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom XDE-175 (spinetoram) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram. 08May2013 2013 doi:10.2903/j.efsa.2013.3220
+Spinetoram 935545-74-7 mixture or formulation Component is identical to the substance Spinetoram 935545-74-7 (3aR,5aR,9S,13S,14R,16aS,16bR)-13-{[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy}-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-a-L-mannopyranoside Spinetoram (XDE-175) C42H69NO10 CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@@H]3[C@H](C2CC(=O)O1)CC[C@H]4[C@H]3CC(C4)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OCC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C InChI=1S/C42H69NO10/c1-10-27-13-12-14-35(53-37-18-17-34(43(6)7)24(4)49-37)23(3)38(45)33-21-31-29(32(33)22-36(44)51-27)16-15-26-19-28(20-30(26)31)52-42-41(47-9)40(48-11-2)39(46-8)25(5)50-42/h21,23-32,34-35,37,39-42H,10-20,22H2,1-9H3/t23-,24-,25+,26-,27+,28?,29-,30-,31-,32?,34+,35+,37+,39+,40-,41-,42+/m1/s1 organic representative compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom XDE-175 (spinetoram) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram. 08May2013 2013 doi:10.2903/j.efsa.2013.3220
+Spinetoram 935545-74-7 mixture or formulation Component is identical to the substance Spinetoram 935545-74-7 (3aR,5aR,9S,13S,14R,16aS,16bR)-13-{[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy}-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-a-L-mannopyranoside Spinetoram (XDE-175) C42H69NO10 CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@@H]3[C@H](C2CC(=O)O1)CC[C@H]4[C@H]3CC(C4)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OCC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C InChI=1S/C42H69NO10/c1-10-27-13-12-14-35(53-37-18-17-34(43(6)7)24(4)49-37)23(3)38(45)33-21-31-29(32(33)22-36(44)51-27)16-15-26-19-28(20-30(26)31)52-42-41(47-9)40(48-11-2)39(46-8)25(5)50-42/h21,23-32,34-35,37,39-42H,10-20,22H2,1-9H3/t23-,24-,25+,26-,27+,28?,29-,30-,31-,32?,34+,35+,37+,39+,40-,41-,42+/m1/s1 organic representative compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom XDE-175 (spinetoram) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram. 08May2013 2013 doi:10.2903/j.efsa.2013.3220
+Spinetoram 935545-74-7 mixture or formulation Component is identical to the substance Spinetoram 935545-74-7 (3aR,5aR,9S,13S,14R,16aS,16bR)-13-{[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy}-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-a-L-mannopyranoside Spinetoram (XDE-175) C42H69NO10 CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@@H]3[C@H](C2CC(=O)O1)CC[C@H]4[C@H]3CC(C4)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OCC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C InChI=1S/C42H69NO10/c1-10-27-13-12-14-35(53-37-18-17-34(43(6)7)24(4)49-37)23(3)38(45)33-21-31-29(32(33)22-36(44)51-27)16-15-26-19-28(20-30(26)31)52-42-41(47-9)40(48-11-2)39(46-8)25(5)50-42/h21,23-32,34-35,37,39-42H,10-20,22H2,1-9H3/t23-,24-,25+,26-,27+,28?,29-,30-,31-,32?,34+,35+,37+,39+,40-,41-,42+/m1/s1 organic representative compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom XDE-175 (spinetoram) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram. 08May2013 2013 doi:10.2903/j.efsa.2013.3220
+Spinetoram 935545-74-7 mixture or formulation Component is identical to the substance Spinetoram 935545-74-7 (3aR,5aR,9S,13S,14R,16aS,16bR)-13-{[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy}-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-a-L-mannopyranoside Spinetoram (XDE-175) C42H69NO10 CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@@H]3[C@H](C2CC(=O)O1)CC[C@H]4[C@H]3CC(C4)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OCC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C InChI=1S/C42H69NO10/c1-10-27-13-12-14-35(53-37-18-17-34(43(6)7)24(4)49-37)23(3)38(45)33-21-31-29(32(33)22-36(44)51-27)16-15-26-19-28(20-30(26)31)52-42-41(47-9)40(48-11-2)39(46-8)25(5)50-42/h21,23-32,34-35,37,39-42H,10-20,22H2,1-9H3/t23-,24-,25+,26-,27+,28?,29-,30-,31-,32?,34+,35+,37+,39+,40-,41-,42+/m1/s1 organic representative compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom XDE-175 (spinetoram) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram. 08May2013 2013 doi:10.2903/j.efsa.2013.3220
+Spinetoram 935545-74-7 mixture or formulation Component is identical to the substance Spinetoram 935545-74-7 (3aR,5aR,9S,13S,14R,16aS,16bR)-13-{[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy}-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-a-L-mannopyranoside Spinetoram (XDE-175) C42H69NO10 CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@@H]3[C@H](C2CC(=O)O1)CC[C@H]4[C@H]3CC(C4)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OCC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C InChI=1S/C42H69NO10/c1-10-27-13-12-14-35(53-37-18-17-34(43(6)7)24(4)49-37)23(3)38(45)33-21-31-29(32(33)22-36(44)51-27)16-15-26-19-28(20-30(26)31)52-42-41(47-9)40(48-11-2)39(46-8)25(5)50-42/h21,23-32,34-35,37,39-42H,10-20,22H2,1-9H3/t23-,24-,25+,26-,27+,28?,29-,30-,31-,32?,34+,35+,37+,39+,40-,41-,42+/m1/s1 organic representative compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom XDE-175 (spinetoram) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram. 08May2013 2013 doi:10.2903/j.efsa.2013.3220
+Spinetoram 935545-74-7 mixture or formulation Component is identical to the substance Spinetoram 935545-74-7 (3aR,5aR,9S,13S,14R,16aS,16bR)-13-{[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy}-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-a-L-mannopyranoside Spinetoram (XDE-175) C42H69NO10 CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@@H]3[C@H](C2CC(=O)O1)CC[C@H]4[C@H]3CC(C4)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OCC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C InChI=1S/C42H69NO10/c1-10-27-13-12-14-35(53-37-18-17-34(43(6)7)24(4)49-37)23(3)38(45)33-21-31-29(32(33)22-36(44)51-27)16-15-26-19-28(20-30(26)31)52-42-41(47-9)40(48-11-2)39(46-8)25(5)50-42/h21,23-32,34-35,37,39-42H,10-20,22H2,1-9H3/t23-,24-,25+,26-,27+,28?,29-,30-,31-,32?,34+,35+,37+,39+,40-,41-,42+/m1/s1 organic representative compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom XDE-175 (spinetoram) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram. 08May2013 2013 doi:10.2903/j.efsa.2013.3220
+Spinetoram 935545-74-7 mixture or formulation Component is identical to the substance Spinetoram 935545-74-7 (3aR,5aR,9S,13S,14R,16aS,16bR)-13-{[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy}-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-a-L-mannopyranoside Spinetoram (XDE-175) C42H69NO10 CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@@H]3[C@H](C2CC(=O)O1)CC[C@H]4[C@H]3CC(C4)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OCC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C InChI=1S/C42H69NO10/c1-10-27-13-12-14-35(53-37-18-17-34(43(6)7)24(4)49-37)23(3)38(45)33-21-31-29(32(33)22-36(44)51-27)16-15-26-19-28(20-30(26)31)52-42-41(47-9)40(48-11-2)39(46-8)25(5)50-42/h21,23-32,34-35,37,39-42H,10-20,22H2,1-9H3/t23-,24-,25+,26-,27+,28?,29-,30-,31-,32?,34+,35+,37+,39+,40-,41-,42+/m1/s1 organic representative compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom XDE-175 (spinetoram) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram. 08May2013 2013 doi:10.2903/j.efsa.2013.3220
+Spinetoram 935545-74-7 mixture or formulation Component is identical to the substance Spinetoram 935545-74-7 (3aR,5aR,9S,13S,14R,16aS,16bR)-13-{[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy}-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-a-L-mannopyranoside Spinetoram (XDE-175) C42H69NO10 CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@@H]3[C@H](C2CC(=O)O1)CC[C@H]4[C@H]3CC(C4)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OCC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C InChI=1S/C42H69NO10/c1-10-27-13-12-14-35(53-37-18-17-34(43(6)7)24(4)49-37)23(3)38(45)33-21-31-29(32(33)22-36(44)51-27)16-15-26-19-28(20-30(26)31)52-42-41(47-9)40(48-11-2)39(46-8)25(5)50-42/h21,23-32,34-35,37,39-42H,10-20,22H2,1-9H3/t23-,24-,25+,26-,27+,28?,29-,30-,31-,32?,34+,35+,37+,39+,40-,41-,42+/m1/s1 organic representative compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom XDE-175 (spinetoram) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram. 08May2013 2013 doi:10.2903/j.efsa.2013.3220
+Spinetoram 935545-74-7 mixture or formulation Component is identical to the substance Spinetoram 935545-74-7 (3aR,5aR,9S,13S,14R,16aS,16bR)-13-{[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy}-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-a-L-mannopyranoside Spinetoram (XDE-175) C42H69NO10 CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@@H]3[C@H](C2CC(=O)O1)CC[C@H]4[C@H]3CC(C4)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OCC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C InChI=1S/C42H69NO10/c1-10-27-13-12-14-35(53-37-18-17-34(43(6)7)24(4)49-37)23(3)38(45)33-21-31-29(32(33)22-36(44)51-27)16-15-26-19-28(20-30(26)31)52-42-41(47-9)40(48-11-2)39(46-8)25(5)50-42/h21,23-32,34-35,37,39-42H,10-20,22H2,1-9H3/t23-,24-,25+,26-,27+,28?,29-,30-,31-,32?,34+,35+,37+,39+,40-,41-,42+/m1/s1 organic representative compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom XDE-175 (spinetoram) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram. 08May2013 2013 doi:10.2903/j.efsa.2013.3220
+Spinetoram 935545-74-7 mixture or formulation Component is identical to the substance Spinetoram 935545-74-7 (3aR,5aR,9S,13S,14R,16aS,16bR)-13-{[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy}-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-a-L-mannopyranoside Spinetoram (XDE-175) C42H69NO10 CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@@H]3[C@H](C2CC(=O)O1)CC[C@H]4[C@H]3CC(C4)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OCC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C InChI=1S/C42H69NO10/c1-10-27-13-12-14-35(53-37-18-17-34(43(6)7)24(4)49-37)23(3)38(45)33-21-31-29(32(33)22-36(44)51-27)16-15-26-19-28(20-30(26)31)52-42-41(47-9)40(48-11-2)39(46-8)25(5)50-42/h21,23-32,34-35,37,39-42H,10-20,22H2,1-9H3/t23-,24-,25+,26-,27+,28?,29-,30-,31-,32?,34+,35+,37+,39+,40-,41-,42+/m1/s1 organic representative compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom XDE-175 (spinetoram) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram. 08May2013 2013 doi:10.2903/j.efsa.2013.3220
+Spinetoram 935545-74-7 mixture or formulation Component is identical to the substance Spinetoram 935545-74-7 (3aR,5aR,9S,13S,14R,16aS,16bR)-13-{[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy}-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-a-L-mannopyranoside Spinetoram (XDE-175) C42H69NO10 CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@@H]3[C@H](C2CC(=O)O1)CC[C@H]4[C@H]3CC(C4)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OCC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C InChI=1S/C42H69NO10/c1-10-27-13-12-14-35(53-37-18-17-34(43(6)7)24(4)49-37)23(3)38(45)33-21-31-29(32(33)22-36(44)51-27)16-15-26-19-28(20-30(26)31)52-42-41(47-9)40(48-11-2)39(46-8)25(5)50-42/h21,23-32,34-35,37,39-42H,10-20,22H2,1-9H3/t23-,24-,25+,26-,27+,28?,29-,30-,31-,32?,34+,35+,37+,39+,40-,41-,42+/m1/s1 organic representative compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom XDE-175 (spinetoram) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram. 08May2013 2013 doi:10.2903/j.efsa.2013.3220
+Spinetoram 935545-74-7 mixture or formulation Component is identical to the substance Spinetoram 935545-74-7 (3aR,5aR,9S,13S,14R,16aS,16bR)-13-{[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy}-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-a-L-mannopyranoside Spinetoram (XDE-175) C42H69NO10 CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@@H]3[C@H](C2CC(=O)O1)CC[C@H]4[C@H]3CC(C4)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OCC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C InChI=1S/C42H69NO10/c1-10-27-13-12-14-35(53-37-18-17-34(43(6)7)24(4)49-37)23(3)38(45)33-21-31-29(32(33)22-36(44)51-27)16-15-26-19-28(20-30(26)31)52-42-41(47-9)40(48-11-2)39(46-8)25(5)50-42/h21,23-32,34-35,37,39-42H,10-20,22H2,1-9H3/t23-,24-,25+,26-,27+,28?,29-,30-,31-,32?,34+,35+,37+,39+,40-,41-,42+/m1/s1 organic representative compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom XDE-175 (spinetoram) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram. 08May2013 2013 doi:10.2903/j.efsa.2013.3220
+Spinetoram 935545-74-7 mixture or formulation Component is identical to the substance Spinetoram 935545-74-7 (3aR,5aR,9S,13S,14R,16aS,16bR)-13-{[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy}-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-a-L-mannopyranoside Spinetoram (XDE-175) C42H69NO10 CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@@H]3[C@H](C2CC(=O)O1)CC[C@H]4[C@H]3CC(C4)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OCC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C InChI=1S/C42H69NO10/c1-10-27-13-12-14-35(53-37-18-17-34(43(6)7)24(4)49-37)23(3)38(45)33-21-31-29(32(33)22-36(44)51-27)16-15-26-19-28(20-30(26)31)52-42-41(47-9)40(48-11-2)39(46-8)25(5)50-42/h21,23-32,34-35,37,39-42H,10-20,22H2,1-9H3/t23-,24-,25+,26-,27+,28?,29-,30-,31-,32?,34+,35+,37+,39+,40-,41-,42+/m1/s1 organic representative compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom XDE-175 (spinetoram) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram. 08May2013 2013 doi:10.2903/j.efsa.2013.3220
+Spinetoram 935545-74-7 mixture or formulation Component is identical to the substance Spinetoram 935545-74-7 (3aR,5aR,9S,13S,14R,16aS,16bR)-13-{[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy}-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-a-L-mannopyranoside Spinetoram (XDE-175) C42H69NO10 CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@@H]3[C@H](C2CC(=O)O1)CC[C@H]4[C@H]3CC(C4)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OCC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C InChI=1S/C42H69NO10/c1-10-27-13-12-14-35(53-37-18-17-34(43(6)7)24(4)49-37)23(3)38(45)33-21-31-29(32(33)22-36(44)51-27)16-15-26-19-28(20-30(26)31)52-42-41(47-9)40(48-11-2)39(46-8)25(5)50-42/h21,23-32,34-35,37,39-42H,10-20,22H2,1-9H3/t23-,24-,25+,26-,27+,28?,29-,30-,31-,32?,34+,35+,37+,39+,40-,41-,42+/m1/s1 organic representative compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom XDE-175 (spinetoram) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram. 08May2013 2013 doi:10.2903/j.efsa.2013.3220
+Spinetoram 935545-74-7 mixture or formulation Component is identical to the substance Spinetoram 935545-74-7 (3aR,5aR,9S,13S,14R,16aS,16bR)-13-{[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy}-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-a-L-mannopyranoside Spinetoram (XDE-175) C42H69NO10 CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@@H]3[C@H](C2CC(=O)O1)CC[C@H]4[C@H]3CC(C4)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OCC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C InChI=1S/C42H69NO10/c1-10-27-13-12-14-35(53-37-18-17-34(43(6)7)24(4)49-37)23(3)38(45)33-21-31-29(32(33)22-36(44)51-27)16-15-26-19-28(20-30(26)31)52-42-41(47-9)40(48-11-2)39(46-8)25(5)50-42/h21,23-32,34-35,37,39-42H,10-20,22H2,1-9H3/t23-,24-,25+,26-,27+,28?,29-,30-,31-,32?,34+,35+,37+,39+,40-,41-,42+/m1/s1 organic representative compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom XDE-175 (spinetoram) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram. 08May2013 2013 doi:10.2903/j.efsa.2013.3220
+Spinetoram 935545-74-7 mixture or formulation Component is identical to the substance Spinetoram 935545-74-7 (3aR,5aR,9S,13S,14R,16aS,16bR)-13-{[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy}-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-a-L-mannopyranoside Spinetoram (XDE-175) C42H69NO10 CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@@H]3[C@H](C2CC(=O)O1)CC[C@H]4[C@H]3CC(C4)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OCC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C InChI=1S/C42H69NO10/c1-10-27-13-12-14-35(53-37-18-17-34(43(6)7)24(4)49-37)23(3)38(45)33-21-31-29(32(33)22-36(44)51-27)16-15-26-19-28(20-30(26)31)52-42-41(47-9)40(48-11-2)39(46-8)25(5)50-42/h21,23-32,34-35,37,39-42H,10-20,22H2,1-9H3/t23-,24-,25+,26-,27+,28?,29-,30-,31-,32?,34+,35+,37+,39+,40-,41-,42+/m1/s1 organic representative compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom XDE-175 (spinetoram) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram. 08May2013 2013 doi:10.2903/j.efsa.2013.3220
+Spinetoram 935545-74-7 mixture or formulation Component is identical to the substance Spinetoram 935545-74-7 (3aR,5aR,9S,13S,14R,16aS,16bR)-13-{[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy}-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-a-L-mannopyranoside Spinetoram (XDE-175) C42H69NO10 CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@@H]3[C@H](C2CC(=O)O1)CC[C@H]4[C@H]3CC(C4)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OCC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C InChI=1S/C42H69NO10/c1-10-27-13-12-14-35(53-37-18-17-34(43(6)7)24(4)49-37)23(3)38(45)33-21-31-29(32(33)22-36(44)51-27)16-15-26-19-28(20-30(26)31)52-42-41(47-9)40(48-11-2)39(46-8)25(5)50-42/h21,23-32,34-35,37,39-42H,10-20,22H2,1-9H3/t23-,24-,25+,26-,27+,28?,29-,30-,31-,32?,34+,35+,37+,39+,40-,41-,42+/m1/s1 organic representative compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom XDE-175 (spinetoram) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram. 08May2013 2013 doi:10.2903/j.efsa.2013.3220
+Spinetoram 935545-74-7 mixture or formulation Component is identical to the substance Spinetoram 935545-74-7 (3aR,5aR,9S,13S,14R,16aS,16bR)-13-{[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy}-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-a-L-mannopyranoside Spinetoram (XDE-175) C42H69NO10 CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@@H]3[C@H](C2CC(=O)O1)CC[C@H]4[C@H]3CC(C4)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OCC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C InChI=1S/C42H69NO10/c1-10-27-13-12-14-35(53-37-18-17-34(43(6)7)24(4)49-37)23(3)38(45)33-21-31-29(32(33)22-36(44)51-27)16-15-26-19-28(20-30(26)31)52-42-41(47-9)40(48-11-2)39(46-8)25(5)50-42/h21,23-32,34-35,37,39-42H,10-20,22H2,1-9H3/t23-,24-,25+,26-,27+,28?,29-,30-,31-,32?,34+,35+,37+,39+,40-,41-,42+/m1/s1 organic representative compound PubChem isomeric SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Rat (as animal) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom XDE-175 (spinetoram) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram. 08May2013 2013 doi:10.2903/j.efsa.2013.3220
+Spinetoram 935545-74-7 mixture or formulation Component is identical to the substance Spinetoram 935545-74-7 (3aR,5aR,9S,13S,14R,16aS,16bR)-13-{[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy}-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-a-L-mannopyranoside Spinetoram (XDE-175) C42H69NO10 CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@@H]3[C@H](C2CC(=O)O1)CC[C@H]4[C@H]3CC(C4)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OCC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C InChI=1S/C42H69NO10/c1-10-27-13-12-14-35(53-37-18-17-34(43(6)7)24(4)49-37)23(3)38(45)33-21-31-29(32(33)22-36(44)51-27)16-15-26-19-28(20-30(26)31)52-42-41(47-9)40(48-11-2)39(46-8)25(5)50-42/h21,23-32,34-35,37,39-42H,10-20,22H2,1-9H3/t23-,24-,25+,26-,27+,28?,29-,30-,31-,32?,34+,35+,37+,39+,40-,41-,42+/m1/s1 organic representative compound PubChem isomeric SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Rat (as animal) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom XDE-175 (spinetoram) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram. 08May2013 2013 doi:10.2903/j.efsa.2013.3220
+Spinetoram 935545-74-7 mixture or formulation Component is identical to the substance Spinetoram 935545-74-7 (3aR,5aR,9S,13S,14R,16aS,16bR)-13-{[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy}-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-a-L-mannopyranoside Spinetoram (XDE-175) C42H69NO10 CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@@H]3[C@H](C2CC(=O)O1)CC[C@H]4[C@H]3CC(C4)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OCC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C InChI=1S/C42H69NO10/c1-10-27-13-12-14-35(53-37-18-17-34(43(6)7)24(4)49-37)23(3)38(45)33-21-31-29(32(33)22-36(44)51-27)16-15-26-19-28(20-30(26)31)52-42-41(47-9)40(48-11-2)39(46-8)25(5)50-42/h21,23-32,34-35,37,39-42H,10-20,22H2,1-9H3/t23-,24-,25+,26-,27+,28?,29-,30-,31-,32?,34+,35+,37+,39+,40-,41-,42+/m1/s1 organic representative compound PubChem isomeric SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Rat (as animal) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom XDE-175 (spinetoram) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram. 08May2013 2013 doi:10.2903/j.efsa.2013.3220
+Spinetoram 935545-74-7 mixture or formulation Component is identical to the substance Spinetoram 935545-74-7 (3aR,5aR,9S,13S,14R,16aS,16bR)-13-{[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy}-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-a-L-mannopyranoside Spinetoram (XDE-175) C42H69NO10 CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@@H]3[C@H](C2CC(=O)O1)CC[C@H]4[C@H]3CC(C4)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OCC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C InChI=1S/C42H69NO10/c1-10-27-13-12-14-35(53-37-18-17-34(43(6)7)24(4)49-37)23(3)38(45)33-21-31-29(32(33)22-36(44)51-27)16-15-26-19-28(20-30(26)31)52-42-41(47-9)40(48-11-2)39(46-8)25(5)50-42/h21,23-32,34-35,37,39-42H,10-20,22H2,1-9H3/t23-,24-,25+,26-,27+,28?,29-,30-,31-,32?,34+,35+,37+,39+,40-,41-,42+/m1/s1 organic representative compound PubChem isomeric SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Rat (as animal) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom XDE-175 (spinetoram) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram. 08May2013 2013 doi:10.2903/j.efsa.2013.3220
+Spinetoram 935545-74-7 mixture or formulation Component is identical to the substance Spinetoram 935545-74-7 (3aR,5aR,9S,13S,14R,16aS,16bR)-13-{[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy}-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-a-L-mannopyranoside Spinetoram (XDE-175) C42H69NO10 CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@@H]3[C@H](C2CC(=O)O1)CC[C@H]4[C@H]3CC(C4)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OCC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C InChI=1S/C42H69NO10/c1-10-27-13-12-14-35(53-37-18-17-34(43(6)7)24(4)49-37)23(3)38(45)33-21-31-29(32(33)22-36(44)51-27)16-15-26-19-28(20-30(26)31)52-42-41(47-9)40(48-11-2)39(46-8)25(5)50-42/h21,23-32,34-35,37,39-42H,10-20,22H2,1-9H3/t23-,24-,25+,26-,27+,28?,29-,30-,31-,32?,34+,35+,37+,39+,40-,41-,42+/m1/s1 organic representative compound PubChem isomeric SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: The United Kingdom XDE-175 (spinetoram) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram. 08May2013 2013 doi:10.2903/j.efsa.2013.3220
+Spinetoram 935545-74-7 mixture or formulation Component is identical to the substance Spinetoram 935545-74-7 (3aR,5aR,9S,13S,14R,16aS,16bR)-13-{[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy}-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-a-L-mannopyranoside Spinetoram (XDE-175) C42H69NO10 CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@@H]3[C@H](C2CC(=O)O1)CC[C@H]4[C@H]3CC(C4)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OCC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C InChI=1S/C42H69NO10/c1-10-27-13-12-14-35(53-37-18-17-34(43(6)7)24(4)49-37)23(3)38(45)33-21-31-29(32(33)22-36(44)51-27)16-15-26-19-28(20-30(26)31)52-42-41(47-9)40(48-11-2)39(46-8)25(5)50-42/h21,23-32,34-35,37,39-42H,10-20,22H2,1-9H3/t23-,24-,25+,26-,27+,28?,29-,30-,31-,32?,34+,35+,37+,39+,40-,41-,42+/m1/s1 organic representative compound PubChem isomeric SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: The United Kingdom XDE-175 (spinetoram) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram. 08May2013 2013 doi:10.2903/j.efsa.2013.3220
+Spinetoram 935545-74-7 mixture or formulation Component is identical to the substance Spinetoram 935545-74-7 (3aR,5aR,9S,13S,14R,16aS,16bR)-13-{[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy}-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-a-L-mannopyranoside Spinetoram (XDE-175) C42H69NO10 CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@@H]3[C@H](C2CC(=O)O1)CC[C@H]4[C@H]3CC(C4)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OCC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C InChI=1S/C42H69NO10/c1-10-27-13-12-14-35(53-37-18-17-34(43(6)7)24(4)49-37)23(3)38(45)33-21-31-29(32(33)22-36(44)51-27)16-15-26-19-28(20-30(26)31)52-42-41(47-9)40(48-11-2)39(46-8)25(5)50-42/h21,23-32,34-35,37,39-42H,10-20,22H2,1-9H3/t23-,24-,25+,26-,27+,28?,29-,30-,31-,32?,34+,35+,37+,39+,40-,41-,42+/m1/s1 organic representative compound PubChem isomeric SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: The United Kingdom XDE-175 (spinetoram) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram. 08May2013 2013 doi:10.2903/j.efsa.2013.3220
+Spinetoram 935545-74-7 mixture or formulation Component is identical to the substance Spinetoram 935545-74-7 (3aR,5aR,9S,13S,14R,16aS,16bR)-13-{[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy}-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-a-L-mannopyranoside Spinetoram (XDE-175) C42H69NO10 CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@@H]3[C@H](C2CC(=O)O1)CC[C@H]4[C@H]3CC(C4)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OCC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C InChI=1S/C42H69NO10/c1-10-27-13-12-14-35(53-37-18-17-34(43(6)7)24(4)49-37)23(3)38(45)33-21-31-29(32(33)22-36(44)51-27)16-15-26-19-28(20-30(26)31)52-42-41(47-9)40(48-11-2)39(46-8)25(5)50-42/h21,23-32,34-35,37,39-42H,10-20,22H2,1-9H3/t23-,24-,25+,26-,27+,28?,29-,30-,31-,32?,34+,35+,37+,39+,40-,41-,42+/m1/s1 organic representative compound PubChem isomeric SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: The United Kingdom XDE-175 (spinetoram) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram. 08May2013 2013 doi:10.2903/j.efsa.2013.3220
+Spinetoram 935545-74-7 mixture or formulation Component is identical to the substance Spinetoram 935545-74-7 (3aR,5aR,9S,13S,14R,16aS,16bR)-13-{[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy}-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-a-L-mannopyranoside Spinetoram (XDE-175) C42H69NO10 CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@@H]3[C@H](C2CC(=O)O1)CC[C@H]4[C@H]3CC(C4)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OCC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C InChI=1S/C42H69NO10/c1-10-27-13-12-14-35(53-37-18-17-34(43(6)7)24(4)49-37)23(3)38(45)33-21-31-29(32(33)22-36(44)51-27)16-15-26-19-28(20-30(26)31)52-42-41(47-9)40(48-11-2)39(46-8)25(5)50-42/h21,23-32,34-35,37,39-42H,10-20,22H2,1-9H3/t23-,24-,25+,26-,27+,28?,29-,30-,31-,32?,34+,35+,37+,39+,40-,41-,42+/m1/s1 organic representative compound PubChem isomeric SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 6 Male oral: gavage 24.0000000000 h yes not applicable Negative no evidence RMS: The United Kingdom XDE-175 (spinetoram) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram. 08May2013 2013 doi:10.2903/j.efsa.2013.3220
+Spinetoram 935545-74-7 single chemical entity Component is a metabolite of the substance N-demethyl-175-J (2R,3aR,5aR,5bS,9S,13S,14R,16aS,16bR)-9-ethyl-14-methyl-13-{[(2S,5S,6R)-6-methyl-5-(methylamino)tetrahydro-2H-pyran-2-yl]oxy}-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-alpha-L-mannopyranoside N-demethyl-175-J C41H67NO10 CN[C@H]1CCC(O[C@@H]1C)O[C@H]6CCC[C@H](CC)OC(=O)C[C@@H]5C(=C/[C@@H]2[C@H]5CC[C@@H]3C[C@H](C[C@@H]23)O[C@@H]4O[C@@H](C)[C@H](OC)[C@@H](OCC)[C@H]4OC)\C(=O)[C@@H]6C InChI=1/C41H67NO10/c1-9-26-12-11-13-34(52-36-17-16-33(42-6)23(4)48-36)22(3)37(44)32-20-30-28(31(32)21-35(43)50-26)15-14-25-18-27(19-29(25)30)51-41-40(46-8)39(47-10-2)38(45-7)24(5)49-41/h20,22-31,33-34,36,38-42H,9-19,21H2,1-8H3/t22-,23-,24+,25-,26+,27-,28-,29-,30-,31+,33+,34+,36-,38+,39-,40-,41+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom XDE-175 (spinetoram) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram. 08May2013 2013 doi:10.2903/j.efsa.2013.3220
+Spinetoram 935545-74-7 single chemical entity Component is a metabolite of the substance N-demethyl-175-J (2R,3aR,5aR,5bS,9S,13S,14R,16aS,16bR)-9-ethyl-14-methyl-13-{[(2S,5S,6R)-6-methyl-5-(methylamino)tetrahydro-2H-pyran-2-yl]oxy}-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-alpha-L-mannopyranoside N-demethyl-175-J C41H67NO10 CN[C@H]1CCC(O[C@@H]1C)O[C@H]6CCC[C@H](CC)OC(=O)C[C@@H]5C(=C/[C@@H]2[C@H]5CC[C@@H]3C[C@H](C[C@@H]23)O[C@@H]4O[C@@H](C)[C@H](OC)[C@@H](OCC)[C@H]4OC)\C(=O)[C@@H]6C InChI=1/C41H67NO10/c1-9-26-12-11-13-34(52-36-17-16-33(42-6)23(4)48-36)22(3)37(44)32-20-30-28(31(32)21-35(43)50-26)15-14-25-18-27(19-29(25)30)51-41-40(46-8)39(47-10-2)38(45-7)24(5)49-41/h20,22-31,33-34,36,38-42H,9-19,21H2,1-8H3/t22-,23-,24+,25-,26+,27-,28-,29-,30-,31+,33+,34+,36-,38+,39-,40-,41+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom XDE-175 (spinetoram) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram. 08May2013 2013 doi:10.2903/j.efsa.2013.3220
+Spinetoram 935545-74-7 single chemical entity Component is a metabolite of the substance N-demethyl-175-J (2R,3aR,5aR,5bS,9S,13S,14R,16aS,16bR)-9-ethyl-14-methyl-13-{[(2S,5S,6R)-6-methyl-5-(methylamino)tetrahydro-2H-pyran-2-yl]oxy}-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-alpha-L-mannopyranoside N-demethyl-175-J C41H67NO10 CN[C@H]1CCC(O[C@@H]1C)O[C@H]6CCC[C@H](CC)OC(=O)C[C@@H]5C(=C/[C@@H]2[C@H]5CC[C@@H]3C[C@H](C[C@@H]23)O[C@@H]4O[C@@H](C)[C@H](OC)[C@@H](OCC)[C@H]4OC)\C(=O)[C@@H]6C InChI=1/C41H67NO10/c1-9-26-12-11-13-34(52-36-17-16-33(42-6)23(4)48-36)22(3)37(44)32-20-30-28(31(32)21-35(43)50-26)15-14-25-18-27(19-29(25)30)51-41-40(46-8)39(47-10-2)38(45-7)24(5)49-41/h20,22-31,33-34,36,38-42H,9-19,21H2,1-8H3/t22-,23-,24+,25-,26+,27-,28-,29-,30-,31+,33+,34+,36-,38+,39-,40-,41+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom XDE-175 (spinetoram) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram. 08May2013 2013 doi:10.2903/j.efsa.2013.3220
+Spinetoram 935545-74-7 single chemical entity Component is a metabolite of the substance N-demethyl-175-J (2R,3aR,5aR,5bS,9S,13S,14R,16aS,16bR)-9-ethyl-14-methyl-13-{[(2S,5S,6R)-6-methyl-5-(methylamino)tetrahydro-2H-pyran-2-yl]oxy}-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-alpha-L-mannopyranoside N-demethyl-175-J C41H67NO10 CN[C@H]1CCC(O[C@@H]1C)O[C@H]6CCC[C@H](CC)OC(=O)C[C@@H]5C(=C/[C@@H]2[C@H]5CC[C@@H]3C[C@H](C[C@@H]23)O[C@@H]4O[C@@H](C)[C@H](OC)[C@@H](OCC)[C@H]4OC)\C(=O)[C@@H]6C InChI=1/C41H67NO10/c1-9-26-12-11-13-34(52-36-17-16-33(42-6)23(4)48-36)22(3)37(44)32-20-30-28(31(32)21-35(43)50-26)15-14-25-18-27(19-29(25)30)51-41-40(46-8)39(47-10-2)38(45-7)24(5)49-41/h20,22-31,33-34,36,38-42H,9-19,21H2,1-8H3/t22-,23-,24+,25-,26+,27-,28-,29-,30-,31+,33+,34+,36-,38+,39-,40-,41+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom XDE-175 (spinetoram) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram. 08May2013 2013 doi:10.2903/j.efsa.2013.3220
+Spinetoram 935545-74-7 single chemical entity Component is a metabolite of the substance N-demethyl-175-J (2R,3aR,5aR,5bS,9S,13S,14R,16aS,16bR)-9-ethyl-14-methyl-13-{[(2S,5S,6R)-6-methyl-5-(methylamino)tetrahydro-2H-pyran-2-yl]oxy}-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-alpha-L-mannopyranoside N-demethyl-175-J C41H67NO10 CN[C@H]1CCC(O[C@@H]1C)O[C@H]6CCC[C@H](CC)OC(=O)C[C@@H]5C(=C/[C@@H]2[C@H]5CC[C@@H]3C[C@H](C[C@@H]23)O[C@@H]4O[C@@H](C)[C@H](OC)[C@@H](OCC)[C@H]4OC)\C(=O)[C@@H]6C InChI=1/C41H67NO10/c1-9-26-12-11-13-34(52-36-17-16-33(42-6)23(4)48-36)22(3)37(44)32-20-30-28(31(32)21-35(43)50-26)15-14-25-18-27(19-29(25)30)51-41-40(46-8)39(47-10-2)38(45-7)24(5)49-41/h20,22-31,33-34,36,38-42H,9-19,21H2,1-8H3/t22-,23-,24+,25-,26+,27-,28-,29-,30-,31+,33+,34+,36-,38+,39-,40-,41+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom XDE-175 (spinetoram) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram. 08May2013 2013 doi:10.2903/j.efsa.2013.3220
+Spinetoram 935545-74-7 single chemical entity Component is a metabolite of the substance N-demethyl-175-J (2R,3aR,5aR,5bS,9S,13S,14R,16aS,16bR)-9-ethyl-14-methyl-13-{[(2S,5S,6R)-6-methyl-5-(methylamino)tetrahydro-2H-pyran-2-yl]oxy}-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-alpha-L-mannopyranoside N-demethyl-175-J C41H67NO10 CN[C@H]1CCC(O[C@@H]1C)O[C@H]6CCC[C@H](CC)OC(=O)C[C@@H]5C(=C/[C@@H]2[C@H]5CC[C@@H]3C[C@H](C[C@@H]23)O[C@@H]4O[C@@H](C)[C@H](OC)[C@@H](OCC)[C@H]4OC)\C(=O)[C@@H]6C InChI=1/C41H67NO10/c1-9-26-12-11-13-34(52-36-17-16-33(42-6)23(4)48-36)22(3)37(44)32-20-30-28(31(32)21-35(43)50-26)15-14-25-18-27(19-29(25)30)51-41-40(46-8)39(47-10-2)38(45-7)24(5)49-41/h20,22-31,33-34,36,38-42H,9-19,21H2,1-8H3/t22-,23-,24+,25-,26+,27-,28-,29-,30-,31+,33+,34+,36-,38+,39-,40-,41+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom XDE-175 (spinetoram) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram. 08May2013 2013 doi:10.2903/j.efsa.2013.3220
+Spinetoram 935545-74-7 single chemical entity Component is a metabolite of the substance N-demethyl-175-J (2R,3aR,5aR,5bS,9S,13S,14R,16aS,16bR)-9-ethyl-14-methyl-13-{[(2S,5S,6R)-6-methyl-5-(methylamino)tetrahydro-2H-pyran-2-yl]oxy}-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-alpha-L-mannopyranoside N-demethyl-175-J C41H67NO10 CN[C@H]1CCC(O[C@@H]1C)O[C@H]6CCC[C@H](CC)OC(=O)C[C@@H]5C(=C/[C@@H]2[C@H]5CC[C@@H]3C[C@H](C[C@@H]23)O[C@@H]4O[C@@H](C)[C@H](OC)[C@@H](OCC)[C@H]4OC)\C(=O)[C@@H]6C InChI=1/C41H67NO10/c1-9-26-12-11-13-34(52-36-17-16-33(42-6)23(4)48-36)22(3)37(44)32-20-30-28(31(32)21-35(43)50-26)15-14-25-18-27(19-29(25)30)51-41-40(46-8)39(47-10-2)38(45-7)24(5)49-41/h20,22-31,33-34,36,38-42H,9-19,21H2,1-8H3/t22-,23-,24+,25-,26+,27-,28-,29-,30-,31+,33+,34+,36-,38+,39-,40-,41+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom XDE-175 (spinetoram) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram. 08May2013 2013 doi:10.2903/j.efsa.2013.3220
+Spinetoram 935545-74-7 single chemical entity Component is a metabolite of the substance N-demethyl-175-J (2R,3aR,5aR,5bS,9S,13S,14R,16aS,16bR)-9-ethyl-14-methyl-13-{[(2S,5S,6R)-6-methyl-5-(methylamino)tetrahydro-2H-pyran-2-yl]oxy}-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-alpha-L-mannopyranoside N-demethyl-175-J C41H67NO10 CN[C@H]1CCC(O[C@@H]1C)O[C@H]6CCC[C@H](CC)OC(=O)C[C@@H]5C(=C/[C@@H]2[C@H]5CC[C@@H]3C[C@H](C[C@@H]23)O[C@@H]4O[C@@H](C)[C@H](OC)[C@@H](OCC)[C@H]4OC)\C(=O)[C@@H]6C InChI=1/C41H67NO10/c1-9-26-12-11-13-34(52-36-17-16-33(42-6)23(4)48-36)22(3)37(44)32-20-30-28(31(32)21-35(43)50-26)15-14-25-18-27(19-29(25)30)51-41-40(46-8)39(47-10-2)38(45-7)24(5)49-41/h20,22-31,33-34,36,38-42H,9-19,21H2,1-8H3/t22-,23-,24+,25-,26+,27-,28-,29-,30-,31+,33+,34+,36-,38+,39-,40-,41+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom XDE-175 (spinetoram) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram. 08May2013 2013 doi:10.2903/j.efsa.2013.3220
+Spinetoram 935545-74-7 single chemical entity Component is a metabolite of the substance N-demethyl-175-J (2R,3aR,5aR,5bS,9S,13S,14R,16aS,16bR)-9-ethyl-14-methyl-13-{[(2S,5S,6R)-6-methyl-5-(methylamino)tetrahydro-2H-pyran-2-yl]oxy}-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-alpha-L-mannopyranoside N-demethyl-175-J C41H67NO10 CN[C@H]1CCC(O[C@@H]1C)O[C@H]6CCC[C@H](CC)OC(=O)C[C@@H]5C(=C/[C@@H]2[C@H]5CC[C@@H]3C[C@H](C[C@@H]23)O[C@@H]4O[C@@H](C)[C@H](OC)[C@@H](OCC)[C@H]4OC)\C(=O)[C@@H]6C InChI=1/C41H67NO10/c1-9-26-12-11-13-34(52-36-17-16-33(42-6)23(4)48-36)22(3)37(44)32-20-30-28(31(32)21-35(43)50-26)15-14-25-18-27(19-29(25)30)51-41-40(46-8)39(47-10-2)38(45-7)24(5)49-41/h20,22-31,33-34,36,38-42H,9-19,21H2,1-8H3/t22-,23-,24+,25-,26+,27-,28-,29-,30-,31+,33+,34+,36-,38+,39-,40-,41+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom XDE-175 (spinetoram) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram. 08May2013 2013 doi:10.2903/j.efsa.2013.3220
+Spinetoram 935545-74-7 single chemical entity Component is a metabolite of the substance N-demethyl-175-J (2R,3aR,5aR,5bS,9S,13S,14R,16aS,16bR)-9-ethyl-14-methyl-13-{[(2S,5S,6R)-6-methyl-5-(methylamino)tetrahydro-2H-pyran-2-yl]oxy}-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-alpha-L-mannopyranoside N-demethyl-175-J C41H67NO10 CN[C@H]1CCC(O[C@@H]1C)O[C@H]6CCC[C@H](CC)OC(=O)C[C@@H]5C(=C/[C@@H]2[C@H]5CC[C@@H]3C[C@H](C[C@@H]23)O[C@@H]4O[C@@H](C)[C@H](OC)[C@@H](OCC)[C@H]4OC)\C(=O)[C@@H]6C InChI=1/C41H67NO10/c1-9-26-12-11-13-34(52-36-17-16-33(42-6)23(4)48-36)22(3)37(44)32-20-30-28(31(32)21-35(43)50-26)15-14-25-18-27(19-29(25)30)51-41-40(46-8)39(47-10-2)38(45-7)24(5)49-41/h20,22-31,33-34,36,38-42H,9-19,21H2,1-8H3/t22-,23-,24+,25-,26+,27-,28-,29-,30-,31+,33+,34+,36-,38+,39-,40-,41+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom XDE-175 (spinetoram) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram. 08May2013 2013 doi:10.2903/j.efsa.2013.3220
+Spinetoram 935545-74-7 single chemical entity Component is a metabolite of the substance N-formyl-175-J N-[(2R,3S,6R)-6-({(2R,3aR,5aR,5bS,9S,14R,16aS,16bR)-2-[(6-deoxy-3-O-ethyl-2,4-di-O-methyl-L-mannopyranosyl)oxy]-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-13-yl}oxy)-2-methyloxan-3-yl]formamide Not in list C41H65NO11 O=CN[C@H]1CC[C@@H](O[C@@H]1C)OC2CCC[C@H](CC)OC(=O)C[C@@H]3C(=C[C@@H]4[C@H]3CC[C@@H]5C[C@H](C[C@H]54)OC6O[C@@H](C)[C@H](OC)[C@@H](OCC)[C@H]6OC)C(=O)[C@@H]2C InChI=1S/C41H65NO11/c1-8-26-11-10-12-34(53-36-16-15-33(42-21-43)23(4)49-36)22(3)37(45)32-19-30-28(31(32)20-35(44)51-26)14-13-25-17-27(18-29(25)30)52-41-40(47-7)39(48-9-2)38(46-6)24(5)50-41/h19,21-31,33-34,36,38-41H,8-18,20H2,1-7H3,(H,42,43)/t22-,23-,24+,25-,26+,27-,28-,29-,30-,31+,33+,34?,36+,38+,39-,40-,41?/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom XDE-175 (spinetoram) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram. 08May2013 2013 doi:10.2903/j.efsa.2013.3220
+Spinetoram 935545-74-7 single chemical entity Component is a metabolite of the substance N-formyl-175-J N-[(2R,3S,6R)-6-({(2R,3aR,5aR,5bS,9S,14R,16aS,16bR)-2-[(6-deoxy-3-O-ethyl-2,4-di-O-methyl-L-mannopyranosyl)oxy]-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-13-yl}oxy)-2-methyloxan-3-yl]formamide Not in list C41H65NO11 O=CN[C@H]1CC[C@@H](O[C@@H]1C)OC2CCC[C@H](CC)OC(=O)C[C@@H]3C(=C[C@@H]4[C@H]3CC[C@@H]5C[C@H](C[C@H]54)OC6O[C@@H](C)[C@H](OC)[C@@H](OCC)[C@H]6OC)C(=O)[C@@H]2C InChI=1S/C41H65NO11/c1-8-26-11-10-12-34(53-36-16-15-33(42-21-43)23(4)49-36)22(3)37(45)32-19-30-28(31(32)20-35(44)51-26)14-13-25-17-27(18-29(25)30)52-41-40(47-7)39(48-9-2)38(46-6)24(5)50-41/h19,21-31,33-34,36,38-41H,8-18,20H2,1-7H3,(H,42,43)/t22-,23-,24+,25-,26+,27-,28-,29-,30-,31+,33+,34?,36+,38+,39-,40-,41?/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom XDE-175 (spinetoram) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram. 08May2013 2013 doi:10.2903/j.efsa.2013.3220
+Spinetoram 935545-74-7 single chemical entity Component is a metabolite of the substance N-formyl-175-J N-[(2R,3S,6R)-6-({(2R,3aR,5aR,5bS,9S,14R,16aS,16bR)-2-[(6-deoxy-3-O-ethyl-2,4-di-O-methyl-L-mannopyranosyl)oxy]-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-13-yl}oxy)-2-methyloxan-3-yl]formamide Not in list C41H65NO11 O=CN[C@H]1CC[C@@H](O[C@@H]1C)OC2CCC[C@H](CC)OC(=O)C[C@@H]3C(=C[C@@H]4[C@H]3CC[C@@H]5C[C@H](C[C@H]54)OC6O[C@@H](C)[C@H](OC)[C@@H](OCC)[C@H]6OC)C(=O)[C@@H]2C InChI=1S/C41H65NO11/c1-8-26-11-10-12-34(53-36-16-15-33(42-21-43)23(4)49-36)22(3)37(45)32-19-30-28(31(32)20-35(44)51-26)14-13-25-17-27(18-29(25)30)52-41-40(47-7)39(48-9-2)38(46-6)24(5)50-41/h19,21-31,33-34,36,38-41H,8-18,20H2,1-7H3,(H,42,43)/t22-,23-,24+,25-,26+,27-,28-,29-,30-,31+,33+,34?,36+,38+,39-,40-,41?/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom XDE-175 (spinetoram) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram. 08May2013 2013 doi:10.2903/j.efsa.2013.3220
+Spinetoram 935545-74-7 single chemical entity Component is a metabolite of the substance N-formyl-175-J N-[(2R,3S,6R)-6-({(2R,3aR,5aR,5bS,9S,14R,16aS,16bR)-2-[(6-deoxy-3-O-ethyl-2,4-di-O-methyl-L-mannopyranosyl)oxy]-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-13-yl}oxy)-2-methyloxan-3-yl]formamide Not in list C41H65NO11 O=CN[C@H]1CC[C@@H](O[C@@H]1C)OC2CCC[C@H](CC)OC(=O)C[C@@H]3C(=C[C@@H]4[C@H]3CC[C@@H]5C[C@H](C[C@H]54)OC6O[C@@H](C)[C@H](OC)[C@@H](OCC)[C@H]6OC)C(=O)[C@@H]2C InChI=1S/C41H65NO11/c1-8-26-11-10-12-34(53-36-16-15-33(42-21-43)23(4)49-36)22(3)37(45)32-19-30-28(31(32)20-35(44)51-26)14-13-25-17-27(18-29(25)30)52-41-40(47-7)39(48-9-2)38(46-6)24(5)50-41/h19,21-31,33-34,36,38-41H,8-18,20H2,1-7H3,(H,42,43)/t22-,23-,24+,25-,26+,27-,28-,29-,30-,31+,33+,34?,36+,38+,39-,40-,41?/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom XDE-175 (spinetoram) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram. 08May2013 2013 doi:10.2903/j.efsa.2013.3220
+Spinetoram 935545-74-7 single chemical entity Component is a metabolite of the substance N-formyl-175-J N-[(2R,3S,6R)-6-({(2R,3aR,5aR,5bS,9S,14R,16aS,16bR)-2-[(6-deoxy-3-O-ethyl-2,4-di-O-methyl-L-mannopyranosyl)oxy]-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-13-yl}oxy)-2-methyloxan-3-yl]formamide Not in list C41H65NO11 O=CN[C@H]1CC[C@@H](O[C@@H]1C)OC2CCC[C@H](CC)OC(=O)C[C@@H]3C(=C[C@@H]4[C@H]3CC[C@@H]5C[C@H](C[C@H]54)OC6O[C@@H](C)[C@H](OC)[C@@H](OCC)[C@H]6OC)C(=O)[C@@H]2C InChI=1S/C41H65NO11/c1-8-26-11-10-12-34(53-36-16-15-33(42-21-43)23(4)49-36)22(3)37(45)32-19-30-28(31(32)20-35(44)51-26)14-13-25-17-27(18-29(25)30)52-41-40(47-7)39(48-9-2)38(46-6)24(5)50-41/h19,21-31,33-34,36,38-41H,8-18,20H2,1-7H3,(H,42,43)/t22-,23-,24+,25-,26+,27-,28-,29-,30-,31+,33+,34?,36+,38+,39-,40-,41?/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom XDE-175 (spinetoram) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram. 08May2013 2013 doi:10.2903/j.efsa.2013.3220
+Spinetoram 935545-74-7 single chemical entity Component is a metabolite of the substance N-formyl-175-J N-[(2R,3S,6R)-6-({(2R,3aR,5aR,5bS,9S,14R,16aS,16bR)-2-[(6-deoxy-3-O-ethyl-2,4-di-O-methyl-L-mannopyranosyl)oxy]-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-13-yl}oxy)-2-methyloxan-3-yl]formamide Not in list C41H65NO11 O=CN[C@H]1CC[C@@H](O[C@@H]1C)OC2CCC[C@H](CC)OC(=O)C[C@@H]3C(=C[C@@H]4[C@H]3CC[C@@H]5C[C@H](C[C@H]54)OC6O[C@@H](C)[C@H](OC)[C@@H](OCC)[C@H]6OC)C(=O)[C@@H]2C InChI=1S/C41H65NO11/c1-8-26-11-10-12-34(53-36-16-15-33(42-21-43)23(4)49-36)22(3)37(45)32-19-30-28(31(32)20-35(44)51-26)14-13-25-17-27(18-29(25)30)52-41-40(47-7)39(48-9-2)38(46-6)24(5)50-41/h19,21-31,33-34,36,38-41H,8-18,20H2,1-7H3,(H,42,43)/t22-,23-,24+,25-,26+,27-,28-,29-,30-,31+,33+,34?,36+,38+,39-,40-,41?/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom XDE-175 (spinetoram) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram. 08May2013 2013 doi:10.2903/j.efsa.2013.3220
+Spinetoram 935545-74-7 single chemical entity Component is a metabolite of the substance N-formyl-175-J N-[(2R,3S,6R)-6-({(2R,3aR,5aR,5bS,9S,14R,16aS,16bR)-2-[(6-deoxy-3-O-ethyl-2,4-di-O-methyl-L-mannopyranosyl)oxy]-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-13-yl}oxy)-2-methyloxan-3-yl]formamide Not in list C41H65NO11 O=CN[C@H]1CC[C@@H](O[C@@H]1C)OC2CCC[C@H](CC)OC(=O)C[C@@H]3C(=C[C@@H]4[C@H]3CC[C@@H]5C[C@H](C[C@H]54)OC6O[C@@H](C)[C@H](OC)[C@@H](OCC)[C@H]6OC)C(=O)[C@@H]2C InChI=1S/C41H65NO11/c1-8-26-11-10-12-34(53-36-16-15-33(42-21-43)23(4)49-36)22(3)37(45)32-19-30-28(31(32)20-35(44)51-26)14-13-25-17-27(18-29(25)30)52-41-40(47-7)39(48-9-2)38(46-6)24(5)50-41/h19,21-31,33-34,36,38-41H,8-18,20H2,1-7H3,(H,42,43)/t22-,23-,24+,25-,26+,27-,28-,29-,30-,31+,33+,34?,36+,38+,39-,40-,41?/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom XDE-175 (spinetoram) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram. 08May2013 2013 doi:10.2903/j.efsa.2013.3220
+Spinetoram 935545-74-7 single chemical entity Component is a metabolite of the substance N-formyl-175-J N-[(2R,3S,6R)-6-({(2R,3aR,5aR,5bS,9S,14R,16aS,16bR)-2-[(6-deoxy-3-O-ethyl-2,4-di-O-methyl-L-mannopyranosyl)oxy]-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-13-yl}oxy)-2-methyloxan-3-yl]formamide Not in list C41H65NO11 O=CN[C@H]1CC[C@@H](O[C@@H]1C)OC2CCC[C@H](CC)OC(=O)C[C@@H]3C(=C[C@@H]4[C@H]3CC[C@@H]5C[C@H](C[C@H]54)OC6O[C@@H](C)[C@H](OC)[C@@H](OCC)[C@H]6OC)C(=O)[C@@H]2C InChI=1S/C41H65NO11/c1-8-26-11-10-12-34(53-36-16-15-33(42-21-43)23(4)49-36)22(3)37(45)32-19-30-28(31(32)20-35(44)51-26)14-13-25-17-27(18-29(25)30)52-41-40(47-7)39(48-9-2)38(46-6)24(5)50-41/h19,21-31,33-34,36,38-41H,8-18,20H2,1-7H3,(H,42,43)/t22-,23-,24+,25-,26+,27-,28-,29-,30-,31+,33+,34?,36+,38+,39-,40-,41?/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom XDE-175 (spinetoram) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram. 08May2013 2013 doi:10.2903/j.efsa.2013.3220
+Spinetoram 935545-74-7 single chemical entity Component is a metabolite of the substance N-formyl-175-J N-[(2R,3S,6R)-6-({(2R,3aR,5aR,5bS,9S,14R,16aS,16bR)-2-[(6-deoxy-3-O-ethyl-2,4-di-O-methyl-L-mannopyranosyl)oxy]-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-13-yl}oxy)-2-methyloxan-3-yl]formamide Not in list C41H65NO11 O=CN[C@H]1CC[C@@H](O[C@@H]1C)OC2CCC[C@H](CC)OC(=O)C[C@@H]3C(=C[C@@H]4[C@H]3CC[C@@H]5C[C@H](C[C@H]54)OC6O[C@@H](C)[C@H](OC)[C@@H](OCC)[C@H]6OC)C(=O)[C@@H]2C InChI=1S/C41H65NO11/c1-8-26-11-10-12-34(53-36-16-15-33(42-21-43)23(4)49-36)22(3)37(45)32-19-30-28(31(32)20-35(44)51-26)14-13-25-17-27(18-29(25)30)52-41-40(47-7)39(48-9-2)38(46-6)24(5)50-41/h19,21-31,33-34,36,38-41H,8-18,20H2,1-7H3,(H,42,43)/t22-,23-,24+,25-,26+,27-,28-,29-,30-,31+,33+,34?,36+,38+,39-,40-,41?/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom XDE-175 (spinetoram) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram. 08May2013 2013 doi:10.2903/j.efsa.2013.3220
+Spinetoram 935545-74-7 single chemical entity Component is a metabolite of the substance N-formyl-175-J N-[(2R,3S,6R)-6-({(2R,3aR,5aR,5bS,9S,14R,16aS,16bR)-2-[(6-deoxy-3-O-ethyl-2,4-di-O-methyl-L-mannopyranosyl)oxy]-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-13-yl}oxy)-2-methyloxan-3-yl]formamide Not in list C41H65NO11 O=CN[C@H]1CC[C@@H](O[C@@H]1C)OC2CCC[C@H](CC)OC(=O)C[C@@H]3C(=C[C@@H]4[C@H]3CC[C@@H]5C[C@H](C[C@H]54)OC6O[C@@H](C)[C@H](OC)[C@@H](OCC)[C@H]6OC)C(=O)[C@@H]2C InChI=1S/C41H65NO11/c1-8-26-11-10-12-34(53-36-16-15-33(42-21-43)23(4)49-36)22(3)37(45)32-19-30-28(31(32)20-35(44)51-26)14-13-25-17-27(18-29(25)30)52-41-40(47-7)39(48-9-2)38(46-6)24(5)50-41/h19,21-31,33-34,36,38-41H,8-18,20H2,1-7H3,(H,42,43)/t22-,23-,24+,25-,26+,27-,28-,29-,30-,31+,33+,34?,36+,38+,39-,40-,41?/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom XDE-175 (spinetoram) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram. 08May2013 2013 doi:10.2903/j.efsa.2013.3220
+Spinetoram 935545-74-7 single chemical entity Component is a metabolite of the substance N-formyl-175-L N-[(2R,3S,6R)-6-({(2S,3aR,5aS,5bS,9S,14R,16aS,16bS)-2-[(6-deoxy-3-O-ethyl-2,4-di-O-methyl-L-mannopyranosyl)oxy]-9-ethyl-4,14-dimethyl-7,15-dioxo-2,3,3a,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-hexadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-13-yl}oxy)-2-methyloxan-3-yl]formamide Not in list C42H65NO11 O=CN[C@H]1CC[C@@H](O[C@@H]1C)OC2CCC[C@H](CC)OC(=O)C[C@@H]3C(=C[C@@H]4[C@H]3C=C(C)[C@@H]5C[C@H](C[C@H]54)OC6O[C@@H](C)[C@H](OC)[C@@H](OCC)[C@H]6OC)C(=O)[C@@H]2C InChI=1S/C42H65NO11/c1-9-26-12-11-13-35(54-37-15-14-34(43-21-44)24(5)50-37)23(4)38(46)33-19-31-29(32(33)20-36(45)52-26)16-22(3)28-17-27(18-30(28)31)53-42-41(48-8)40(49-10-2)39(47-7)25(6)51-42/h16,19,21,23-32,34-35,37,39-42H,9-15,17-18,20H2,1-8H3,(H,43,44)/t23-,24-,25+,26+,27-,28+,29-,30-,31-,32+,34+,35?,37+,39+,40-,41-,42?/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom XDE-175 (spinetoram) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram. 08May2013 2013 doi:10.2903/j.efsa.2013.3220
+Spinetoram 935545-74-7 single chemical entity Component is a metabolite of the substance N-formyl-175-L N-[(2R,3S,6R)-6-({(2S,3aR,5aS,5bS,9S,14R,16aS,16bS)-2-[(6-deoxy-3-O-ethyl-2,4-di-O-methyl-L-mannopyranosyl)oxy]-9-ethyl-4,14-dimethyl-7,15-dioxo-2,3,3a,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-hexadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-13-yl}oxy)-2-methyloxan-3-yl]formamide Not in list C42H65NO11 O=CN[C@H]1CC[C@@H](O[C@@H]1C)OC2CCC[C@H](CC)OC(=O)C[C@@H]3C(=C[C@@H]4[C@H]3C=C(C)[C@@H]5C[C@H](C[C@H]54)OC6O[C@@H](C)[C@H](OC)[C@@H](OCC)[C@H]6OC)C(=O)[C@@H]2C InChI=1S/C42H65NO11/c1-9-26-12-11-13-35(54-37-15-14-34(43-21-44)24(5)50-37)23(4)38(46)33-19-31-29(32(33)20-36(45)52-26)16-22(3)28-17-27(18-30(28)31)53-42-41(48-8)40(49-10-2)39(47-7)25(6)51-42/h16,19,21,23-32,34-35,37,39-42H,9-15,17-18,20H2,1-8H3,(H,43,44)/t23-,24-,25+,26+,27-,28+,29-,30-,31-,32+,34+,35?,37+,39+,40-,41-,42?/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom XDE-175 (spinetoram) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram. 08May2013 2013 doi:10.2903/j.efsa.2013.3220
+Spinetoram 935545-74-7 single chemical entity Component is a metabolite of the substance N-formyl-175-L N-[(2R,3S,6R)-6-({(2S,3aR,5aS,5bS,9S,14R,16aS,16bS)-2-[(6-deoxy-3-O-ethyl-2,4-di-O-methyl-L-mannopyranosyl)oxy]-9-ethyl-4,14-dimethyl-7,15-dioxo-2,3,3a,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-hexadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-13-yl}oxy)-2-methyloxan-3-yl]formamide Not in list C42H65NO11 O=CN[C@H]1CC[C@@H](O[C@@H]1C)OC2CCC[C@H](CC)OC(=O)C[C@@H]3C(=C[C@@H]4[C@H]3C=C(C)[C@@H]5C[C@H](C[C@H]54)OC6O[C@@H](C)[C@H](OC)[C@@H](OCC)[C@H]6OC)C(=O)[C@@H]2C InChI=1S/C42H65NO11/c1-9-26-12-11-13-35(54-37-15-14-34(43-21-44)24(5)50-37)23(4)38(46)33-19-31-29(32(33)20-36(45)52-26)16-22(3)28-17-27(18-30(28)31)53-42-41(48-8)40(49-10-2)39(47-7)25(6)51-42/h16,19,21,23-32,34-35,37,39-42H,9-15,17-18,20H2,1-8H3,(H,43,44)/t23-,24-,25+,26+,27-,28+,29-,30-,31-,32+,34+,35?,37+,39+,40-,41-,42?/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom XDE-175 (spinetoram) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram. 08May2013 2013 doi:10.2903/j.efsa.2013.3220
+Spinetoram 935545-74-7 single chemical entity Component is a metabolite of the substance N-formyl-175-L N-[(2R,3S,6R)-6-({(2S,3aR,5aS,5bS,9S,14R,16aS,16bS)-2-[(6-deoxy-3-O-ethyl-2,4-di-O-methyl-L-mannopyranosyl)oxy]-9-ethyl-4,14-dimethyl-7,15-dioxo-2,3,3a,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-hexadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-13-yl}oxy)-2-methyloxan-3-yl]formamide Not in list C42H65NO11 O=CN[C@H]1CC[C@@H](O[C@@H]1C)OC2CCC[C@H](CC)OC(=O)C[C@@H]3C(=C[C@@H]4[C@H]3C=C(C)[C@@H]5C[C@H](C[C@H]54)OC6O[C@@H](C)[C@H](OC)[C@@H](OCC)[C@H]6OC)C(=O)[C@@H]2C InChI=1S/C42H65NO11/c1-9-26-12-11-13-35(54-37-15-14-34(43-21-44)24(5)50-37)23(4)38(46)33-19-31-29(32(33)20-36(45)52-26)16-22(3)28-17-27(18-30(28)31)53-42-41(48-8)40(49-10-2)39(47-7)25(6)51-42/h16,19,21,23-32,34-35,37,39-42H,9-15,17-18,20H2,1-8H3,(H,43,44)/t23-,24-,25+,26+,27-,28+,29-,30-,31-,32+,34+,35?,37+,39+,40-,41-,42?/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom XDE-175 (spinetoram) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram. 08May2013 2013 doi:10.2903/j.efsa.2013.3220
+Spinetoram 935545-74-7 single chemical entity Component is a metabolite of the substance N-formyl-175-L N-[(2R,3S,6R)-6-({(2S,3aR,5aS,5bS,9S,14R,16aS,16bS)-2-[(6-deoxy-3-O-ethyl-2,4-di-O-methyl-L-mannopyranosyl)oxy]-9-ethyl-4,14-dimethyl-7,15-dioxo-2,3,3a,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-hexadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-13-yl}oxy)-2-methyloxan-3-yl]formamide Not in list C42H65NO11 O=CN[C@H]1CC[C@@H](O[C@@H]1C)OC2CCC[C@H](CC)OC(=O)C[C@@H]3C(=C[C@@H]4[C@H]3C=C(C)[C@@H]5C[C@H](C[C@H]54)OC6O[C@@H](C)[C@H](OC)[C@@H](OCC)[C@H]6OC)C(=O)[C@@H]2C InChI=1S/C42H65NO11/c1-9-26-12-11-13-35(54-37-15-14-34(43-21-44)24(5)50-37)23(4)38(46)33-19-31-29(32(33)20-36(45)52-26)16-22(3)28-17-27(18-30(28)31)53-42-41(48-8)40(49-10-2)39(47-7)25(6)51-42/h16,19,21,23-32,34-35,37,39-42H,9-15,17-18,20H2,1-8H3,(H,43,44)/t23-,24-,25+,26+,27-,28+,29-,30-,31-,32+,34+,35?,37+,39+,40-,41-,42?/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom XDE-175 (spinetoram) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram. 08May2013 2013 doi:10.2903/j.efsa.2013.3220
+Spinetoram 935545-74-7 single chemical entity Component is a metabolite of the substance N-formyl-175-L N-[(2R,3S,6R)-6-({(2S,3aR,5aS,5bS,9S,14R,16aS,16bS)-2-[(6-deoxy-3-O-ethyl-2,4-di-O-methyl-L-mannopyranosyl)oxy]-9-ethyl-4,14-dimethyl-7,15-dioxo-2,3,3a,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-hexadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-13-yl}oxy)-2-methyloxan-3-yl]formamide Not in list C42H65NO11 O=CN[C@H]1CC[C@@H](O[C@@H]1C)OC2CCC[C@H](CC)OC(=O)C[C@@H]3C(=C[C@@H]4[C@H]3C=C(C)[C@@H]5C[C@H](C[C@H]54)OC6O[C@@H](C)[C@H](OC)[C@@H](OCC)[C@H]6OC)C(=O)[C@@H]2C InChI=1S/C42H65NO11/c1-9-26-12-11-13-35(54-37-15-14-34(43-21-44)24(5)50-37)23(4)38(46)33-19-31-29(32(33)20-36(45)52-26)16-22(3)28-17-27(18-30(28)31)53-42-41(48-8)40(49-10-2)39(47-7)25(6)51-42/h16,19,21,23-32,34-35,37,39-42H,9-15,17-18,20H2,1-8H3,(H,43,44)/t23-,24-,25+,26+,27-,28+,29-,30-,31-,32+,34+,35?,37+,39+,40-,41-,42?/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom XDE-175 (spinetoram) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram. 08May2013 2013 doi:10.2903/j.efsa.2013.3220
+Spinetoram 935545-74-7 single chemical entity Component is a metabolite of the substance N-formyl-175-L N-[(2R,3S,6R)-6-({(2S,3aR,5aS,5bS,9S,14R,16aS,16bS)-2-[(6-deoxy-3-O-ethyl-2,4-di-O-methyl-L-mannopyranosyl)oxy]-9-ethyl-4,14-dimethyl-7,15-dioxo-2,3,3a,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-hexadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-13-yl}oxy)-2-methyloxan-3-yl]formamide Not in list C42H65NO11 O=CN[C@H]1CC[C@@H](O[C@@H]1C)OC2CCC[C@H](CC)OC(=O)C[C@@H]3C(=C[C@@H]4[C@H]3C=C(C)[C@@H]5C[C@H](C[C@H]54)OC6O[C@@H](C)[C@H](OC)[C@@H](OCC)[C@H]6OC)C(=O)[C@@H]2C InChI=1S/C42H65NO11/c1-9-26-12-11-13-35(54-37-15-14-34(43-21-44)24(5)50-37)23(4)38(46)33-19-31-29(32(33)20-36(45)52-26)16-22(3)28-17-27(18-30(28)31)53-42-41(48-8)40(49-10-2)39(47-7)25(6)51-42/h16,19,21,23-32,34-35,37,39-42H,9-15,17-18,20H2,1-8H3,(H,43,44)/t23-,24-,25+,26+,27-,28+,29-,30-,31-,32+,34+,35?,37+,39+,40-,41-,42?/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom XDE-175 (spinetoram) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram. 08May2013 2013 doi:10.2903/j.efsa.2013.3220
+Spinetoram 935545-74-7 single chemical entity Component is a metabolite of the substance N-formyl-175-L N-[(2R,3S,6R)-6-({(2S,3aR,5aS,5bS,9S,14R,16aS,16bS)-2-[(6-deoxy-3-O-ethyl-2,4-di-O-methyl-L-mannopyranosyl)oxy]-9-ethyl-4,14-dimethyl-7,15-dioxo-2,3,3a,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-hexadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-13-yl}oxy)-2-methyloxan-3-yl]formamide Not in list C42H65NO11 O=CN[C@H]1CC[C@@H](O[C@@H]1C)OC2CCC[C@H](CC)OC(=O)C[C@@H]3C(=C[C@@H]4[C@H]3C=C(C)[C@@H]5C[C@H](C[C@H]54)OC6O[C@@H](C)[C@H](OC)[C@@H](OCC)[C@H]6OC)C(=O)[C@@H]2C InChI=1S/C42H65NO11/c1-9-26-12-11-13-35(54-37-15-14-34(43-21-44)24(5)50-37)23(4)38(46)33-19-31-29(32(33)20-36(45)52-26)16-22(3)28-17-27(18-30(28)31)53-42-41(48-8)40(49-10-2)39(47-7)25(6)51-42/h16,19,21,23-32,34-35,37,39-42H,9-15,17-18,20H2,1-8H3,(H,43,44)/t23-,24-,25+,26+,27-,28+,29-,30-,31-,32+,34+,35?,37+,39+,40-,41-,42?/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom XDE-175 (spinetoram) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram. 08May2013 2013 doi:10.2903/j.efsa.2013.3220
+Spinetoram 935545-74-7 single chemical entity Component is a metabolite of the substance N-formyl-175-L N-[(2R,3S,6R)-6-({(2S,3aR,5aS,5bS,9S,14R,16aS,16bS)-2-[(6-deoxy-3-O-ethyl-2,4-di-O-methyl-L-mannopyranosyl)oxy]-9-ethyl-4,14-dimethyl-7,15-dioxo-2,3,3a,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-hexadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-13-yl}oxy)-2-methyloxan-3-yl]formamide Not in list C42H65NO11 O=CN[C@H]1CC[C@@H](O[C@@H]1C)OC2CCC[C@H](CC)OC(=O)C[C@@H]3C(=C[C@@H]4[C@H]3C=C(C)[C@@H]5C[C@H](C[C@H]54)OC6O[C@@H](C)[C@H](OC)[C@@H](OCC)[C@H]6OC)C(=O)[C@@H]2C InChI=1S/C42H65NO11/c1-9-26-12-11-13-35(54-37-15-14-34(43-21-44)24(5)50-37)23(4)38(46)33-19-31-29(32(33)20-36(45)52-26)16-22(3)28-17-27(18-30(28)31)53-42-41(48-8)40(49-10-2)39(47-7)25(6)51-42/h16,19,21,23-32,34-35,37,39-42H,9-15,17-18,20H2,1-8H3,(H,43,44)/t23-,24-,25+,26+,27-,28+,29-,30-,31-,32+,34+,35?,37+,39+,40-,41-,42?/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom XDE-175 (spinetoram) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram. 08May2013 2013 doi:10.2903/j.efsa.2013.3220
+Spinetoram 935545-74-7 single chemical entity Component is a metabolite of the substance N-formyl-175-L N-[(2R,3S,6R)-6-({(2S,3aR,5aS,5bS,9S,14R,16aS,16bS)-2-[(6-deoxy-3-O-ethyl-2,4-di-O-methyl-L-mannopyranosyl)oxy]-9-ethyl-4,14-dimethyl-7,15-dioxo-2,3,3a,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-hexadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-13-yl}oxy)-2-methyloxan-3-yl]formamide Not in list C42H65NO11 O=CN[C@H]1CC[C@@H](O[C@@H]1C)OC2CCC[C@H](CC)OC(=O)C[C@@H]3C(=C[C@@H]4[C@H]3C=C(C)[C@@H]5C[C@H](C[C@H]54)OC6O[C@@H](C)[C@H](OC)[C@@H](OCC)[C@H]6OC)C(=O)[C@@H]2C InChI=1S/C42H65NO11/c1-9-26-12-11-13-35(54-37-15-14-34(43-21-44)24(5)50-37)23(4)38(46)33-19-31-29(32(33)20-36(45)52-26)16-22(3)28-17-27(18-30(28)31)53-42-41(48-8)40(49-10-2)39(47-7)25(6)51-42/h16,19,21,23-32,34-35,37,39-42H,9-15,17-18,20H2,1-8H3,(H,43,44)/t23-,24-,25+,26+,27-,28+,29-,30-,31-,32+,34+,35?,37+,39+,40-,41-,42?/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom XDE-175 (spinetoram) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram. 08May2013 2013 doi:10.2903/j.efsa.2013.3220
+Quinoclamine 220-529-2 2797-51-5 single chemical entity Component is identical to the substance Quinoclamine 220-529-2 2797-51-5 2-amino-3-chloro-1,4-naphthoquinone Quinoclamine C10H6ClNO2 NC1=C(Cl)C(=O)c2ccccc2C1=O InChI=1/C10H6ClNO2/c11-7-8(12)10(14)6-4-2-1-3-5(6)9(7)13/h1-4H,12H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Sweden Quinoclamine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quinoclamine 12Dec2007 2007 doi:10.2903/j.efsa.2007.117r
+Quinoclamine 220-529-2 2797-51-5 single chemical entity Component is identical to the substance Quinoclamine 220-529-2 2797-51-5 2-amino-3-chloro-1,4-naphthoquinone Quinoclamine C10H6ClNO2 NC1=C(Cl)C(=O)c2ccccc2C1=O InChI=1/C10H6ClNO2/c11-7-8(12)10(14)6-4-2-1-3-5(6)9(7)13/h1-4H,12H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Sweden Quinoclamine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quinoclamine 12Dec2007 2007 doi:10.2903/j.efsa.2007.117r
+Quinoclamine 220-529-2 2797-51-5 single chemical entity Component is identical to the substance Quinoclamine 220-529-2 2797-51-5 2-amino-3-chloro-1,4-naphthoquinone Quinoclamine C10H6ClNO2 NC1=C(Cl)C(=O)c2ccccc2C1=O InChI=1/C10H6ClNO2/c11-7-8(12)10(14)6-4-2-1-3-5(6)9(7)13/h1-4H,12H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Sweden Quinoclamine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quinoclamine 12Dec2007 2007 doi:10.2903/j.efsa.2007.117r
+Quinoclamine 220-529-2 2797-51-5 single chemical entity Component is identical to the substance Quinoclamine 220-529-2 2797-51-5 2-amino-3-chloro-1,4-naphthoquinone Quinoclamine C10H6ClNO2 NC1=C(Cl)C(=O)c2ccccc2C1=O InChI=1/C10H6ClNO2/c11-7-8(12)10(14)6-4-2-1-3-5(6)9(7)13/h1-4H,12H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Sweden Quinoclamine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quinoclamine 12Dec2007 2007 doi:10.2903/j.efsa.2007.117r
+Quinoclamine 220-529-2 2797-51-5 single chemical entity Component is identical to the substance Quinoclamine 220-529-2 2797-51-5 2-amino-3-chloro-1,4-naphthoquinone Quinoclamine C10H6ClNO2 NC1=C(Cl)C(=O)c2ccccc2C1=O InChI=1/C10H6ClNO2/c11-7-8(12)10(14)6-4-2-1-3-5(6)9(7)13/h1-4H,12H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Sweden Quinoclamine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quinoclamine 12Dec2007 2007 doi:10.2903/j.efsa.2007.117r
+Quinoclamine 220-529-2 2797-51-5 single chemical entity Component is identical to the substance Quinoclamine 220-529-2 2797-51-5 2-amino-3-chloro-1,4-naphthoquinone Quinoclamine C10H6ClNO2 NC1=C(Cl)C(=O)c2ccccc2C1=O InChI=1/C10H6ClNO2/c11-7-8(12)10(14)6-4-2-1-3-5(6)9(7)13/h1-4H,12H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Sweden Quinoclamine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quinoclamine 12Dec2007 2007 doi:10.2903/j.efsa.2007.117r
+Quinoclamine 220-529-2 2797-51-5 single chemical entity Component is identical to the substance Quinoclamine 220-529-2 2797-51-5 2-amino-3-chloro-1,4-naphthoquinone Quinoclamine C10H6ClNO2 NC1=C(Cl)C(=O)c2ccccc2C1=O InChI=1/C10H6ClNO2/c11-7-8(12)10(14)6-4-2-1-3-5(6)9(7)13/h1-4H,12H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Sweden Quinoclamine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quinoclamine 12Dec2007 2007 doi:10.2903/j.efsa.2007.117r
+Quinoclamine 220-529-2 2797-51-5 single chemical entity Component is identical to the substance Quinoclamine 220-529-2 2797-51-5 2-amino-3-chloro-1,4-naphthoquinone Quinoclamine C10H6ClNO2 NC1=C(Cl)C(=O)c2ccccc2C1=O InChI=1/C10H6ClNO2/c11-7-8(12)10(14)6-4-2-1-3-5(6)9(7)13/h1-4H,12H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Sweden Quinoclamine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quinoclamine 12Dec2007 2007 doi:10.2903/j.efsa.2007.117r
+Quinoclamine 220-529-2 2797-51-5 single chemical entity Component is identical to the substance Quinoclamine 220-529-2 2797-51-5 2-amino-3-chloro-1,4-naphthoquinone Quinoclamine C10H6ClNO2 NC1=C(Cl)C(=O)c2ccccc2C1=O InChI=1/C10H6ClNO2/c11-7-8(12)10(14)6-4-2-1-3-5(6)9(7)13/h1-4H,12H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Sweden Quinoclamine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quinoclamine 12Dec2007 2007 doi:10.2903/j.efsa.2007.117r
+Quinoclamine 220-529-2 2797-51-5 single chemical entity Component is identical to the substance Quinoclamine 220-529-2 2797-51-5 2-amino-3-chloro-1,4-naphthoquinone Quinoclamine C10H6ClNO2 NC1=C(Cl)C(=O)c2ccccc2C1=O InChI=1/C10H6ClNO2/c11-7-8(12)10(14)6-4-2-1-3-5(6)9(7)13/h1-4H,12H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Sweden Quinoclamine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quinoclamine 12Dec2007 2007 doi:10.2903/j.efsa.2007.117r
+Quinoclamine 220-529-2 2797-51-5 single chemical entity Component is identical to the substance Quinoclamine 220-529-2 2797-51-5 2-amino-3-chloro-1,4-naphthoquinone Quinoclamine C10H6ClNO2 NC1=C(Cl)C(=O)c2ccccc2C1=O InChI=1/C10H6ClNO2/c11-7-8(12)10(14)6-4-2-1-3-5(6)9(7)13/h1-4H,12H2 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes without Negative RMS: Sweden Quinoclamine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quinoclamine 12Dec2007 2007 doi:10.2903/j.efsa.2007.117r
+Quinoclamine 220-529-2 2797-51-5 single chemical entity Component is identical to the substance Quinoclamine 220-529-2 2797-51-5 2-amino-3-chloro-1,4-naphthoquinone Quinoclamine C10H6ClNO2 NC1=C(Cl)C(=O)c2ccccc2C1=O InChI=1/C10H6ClNO2/c11-7-8(12)10(14)6-4-2-1-3-5(6)9(7)13/h1-4H,12H2 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes with Positive RMS: Sweden Quinoclamine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quinoclamine 12Dec2007 2007 doi:10.2903/j.efsa.2007.117r
+Quinoclamine 220-529-2 2797-51-5 single chemical entity Component is identical to the substance Quinoclamine 220-529-2 2797-51-5 2-amino-3-chloro-1,4-naphthoquinone Quinoclamine C10H6ClNO2 NC1=C(Cl)C(=O)c2ccccc2C1=O InChI=1/C10H6ClNO2/c11-7-8(12)10(14)6-4-2-1-3-5(6)9(7)13/h1-4H,12H2 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Sweden Quinoclamine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quinoclamine 12Dec2007 2007 doi:10.2903/j.efsa.2007.117r
+Quinoclamine 220-529-2 2797-51-5 single chemical entity Component is identical to the substance Quinoclamine 220-529-2 2797-51-5 2-amino-3-chloro-1,4-naphthoquinone Quinoclamine C10H6ClNO2 NC1=C(Cl)C(=O)c2ccccc2C1=O InChI=1/C10H6ClNO2/c11-7-8(12)10(14)6-4-2-1-3-5(6)9(7)13/h1-4H,12H2 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Sweden Quinoclamine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quinoclamine 12Dec2007 2007 doi:10.2903/j.efsa.2007.117r
+Quinoclamine 220-529-2 2797-51-5 single chemical entity Component is identical to the substance Quinoclamine 220-529-2 2797-51-5 2-amino-3-chloro-1,4-naphthoquinone Quinoclamine C10H6ClNO2 NC1=C(Cl)C(=O)c2ccccc2C1=O InChI=1/C10H6ClNO2/c11-7-8(12)10(14)6-4-2-1-3-5(6)9(7)13/h1-4H,12H2 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) SwissWebster 130 Male/Female intraperitoneal 24.0000000000 h no data not applicable Negative no evidence RMS: Sweden Quinoclamine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quinoclamine 12Dec2007 2007 doi:10.2903/j.efsa.2007.117r
+Quinoclamine 220-529-2 2797-51-5 single chemical entity Component is identical to the substance Quinoclamine 220-529-2 2797-51-5 2-amino-3-chloro-1,4-naphthoquinone Quinoclamine C10H6ClNO2 NC1=C(Cl)C(=O)c2ccccc2C1=O InChI=1/C10H6ClNO2/c11-7-8(12)10(14)6-4-2-1-3-5(6)9(7)13/h1-4H,12H2 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) SwissWebster 130 Male/Female intraperitoneal 48.0000000000 h no data not applicable Negative no evidence RMS: Sweden Quinoclamine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quinoclamine 12Dec2007 2007 doi:10.2903/j.efsa.2007.117r
+Quinoclamine 220-529-2 2797-51-5 single chemical entity Component is identical to the substance Quinoclamine 220-529-2 2797-51-5 2-amino-3-chloro-1,4-naphthoquinone Quinoclamine C10H6ClNO2 NC1=C(Cl)C(=O)c2ccccc2C1=O InChI=1/C10H6ClNO2/c11-7-8(12)10(14)6-4-2-1-3-5(6)9(7)13/h1-4H,12H2 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) SwissWebster 130 Male/Female intraperitoneal 72.0000000000 h no data not applicable Negative no evidence RMS: Sweden Quinoclamine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quinoclamine 12Dec2007 2007 doi:10.2903/j.efsa.2007.117r
+Quinoclamine 220-529-2 2797-51-5 single chemical entity Component is identical to the substance Quinoclamine 220-529-2 2797-51-5 2-amino-3-chloro-1,4-naphthoquinone Quinoclamine C10H6ClNO2 NC1=C(Cl)C(=O)c2ccccc2C1=O InChI=1/C10H6ClNO2/c11-7-8(12)10(14)6-4-2-1-3-5(6)9(7)13/h1-4H,12H2 organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Crj:CD(SD) 48 Male oral: gavage 2.0000000000 h yes not applicable Negative RMS: Sweden Quinoclamine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quinoclamine 12Dec2007 2007 doi:10.2903/j.efsa.2007.117r
+Quinoclamine 220-529-2 2797-51-5 single chemical entity Component is identical to the substance Quinoclamine 220-529-2 2797-51-5 2-amino-3-chloro-1,4-naphthoquinone Quinoclamine C10H6ClNO2 NC1=C(Cl)C(=O)c2ccccc2C1=O InChI=1/C10H6ClNO2/c11-7-8(12)10(14)6-4-2-1-3-5(6)9(7)13/h1-4H,12H2 organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Crj:CD(SD) 48 Male oral: gavage 12.0000000000 h yes not applicable Negative RMS: Sweden Quinoclamine 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quinoclamine 12Dec2007 2007 doi:10.2903/j.efsa.2007.117r
+Tri-allate 218-962-7 2303-17-5 single chemical entity Component is identical to the substance Tri-allate 218-962-7 2303-17-5 S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate Tri-allate C10H16Cl3NOS CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Positive RMS: The United Kingdom Tri-allate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate 16Jul2009 2009 doi:10.2903/j.efsa.2009.181r
+Tri-allate 218-962-7 2303-17-5 single chemical entity Component is identical to the substance Tri-allate 218-962-7 2303-17-5 S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate Tri-allate C10H16Cl3NOS CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Tri-allate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate 16Jul2009 2009 doi:10.2903/j.efsa.2009.181r
+Tri-allate 218-962-7 2303-17-5 single chemical entity Component is identical to the substance Tri-allate 218-962-7 2303-17-5 S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate Tri-allate C10H16Cl3NOS CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Positive RMS: The United Kingdom Tri-allate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate 16Jul2009 2009 doi:10.2903/j.efsa.2009.181r
+Tri-allate 218-962-7 2303-17-5 single chemical entity Component is identical to the substance Tri-allate 218-962-7 2303-17-5 S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate Tri-allate C10H16Cl3NOS CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3 organic compound Other Other gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Saccharomyces cerevisiae (as organism) D4 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Tri-allate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate 16Jul2009 2009 doi:10.2903/j.efsa.2009.181r
+Tri-allate 218-962-7 2303-17-5 single chemical entity Component is identical to the substance Tri-allate 218-962-7 2303-17-5 S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate Tri-allate C10H16Cl3NOS CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Positive RMS: The United Kingdom Tri-allate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate 16Jul2009 2009 doi:10.2903/j.efsa.2009.181r
+Tri-allate 218-962-7 2303-17-5 single chemical entity Component is identical to the substance Tri-allate 218-962-7 2303-17-5 S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate Tri-allate C10H16Cl3NOS CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Tri-allate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate 16Jul2009 2009 doi:10.2903/j.efsa.2009.181r
+Tri-allate 218-962-7 2303-17-5 single chemical entity Component is identical to the substance Tri-allate 218-962-7 2303-17-5 S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate Tri-allate C10H16Cl3NOS CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Positive RMS: The United Kingdom Tri-allate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate 16Jul2009 2009 doi:10.2903/j.efsa.2009.181r
+Tri-allate 218-962-7 2303-17-5 single chemical entity Component is identical to the substance Tri-allate 218-962-7 2303-17-5 S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate Tri-allate C10H16Cl3NOS CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Tri-allate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate 16Jul2009 2009 doi:10.2903/j.efsa.2009.181r
+Tri-allate 218-962-7 2303-17-5 single chemical entity Component is identical to the substance Tri-allate 218-962-7 2303-17-5 S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate Tri-allate C10H16Cl3NOS CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3 organic compound Other Other gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Saccharomyces cerevisiae (as organism) D4 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Tri-allate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate 16Jul2009 2009 doi:10.2903/j.efsa.2009.181r
+Tri-allate 218-962-7 2303-17-5 single chemical entity Component is identical to the substance Tri-allate 218-962-7 2303-17-5 S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate Tri-allate C10H16Cl3NOS CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Tri-allate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate 16Jul2009 2009 doi:10.2903/j.efsa.2009.181r
+Tri-allate 218-962-7 2303-17-5 single chemical entity Component is identical to the substance Tri-allate 218-962-7 2303-17-5 S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate Tri-allate C10H16Cl3NOS CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Tri-allate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate 16Jul2009 2009 doi:10.2903/j.efsa.2009.181r
+Tri-allate 218-962-7 2303-17-5 single chemical entity Component is identical to the substance Tri-allate 218-962-7 2303-17-5 S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate Tri-allate C10H16Cl3NOS CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Positive RMS: The United Kingdom Tri-allate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate 16Jul2009 2009 doi:10.2903/j.efsa.2009.181r
+Tri-allate 218-962-7 2303-17-5 single chemical entity Component is identical to the substance Tri-allate 218-962-7 2303-17-5 S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate Tri-allate C10H16Cl3NOS CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Positive RMS: The United Kingdom Tri-allate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate 16Jul2009 2009 doi:10.2903/j.efsa.2009.181r
+Tri-allate 218-962-7 2303-17-5 single chemical entity Component is identical to the substance Tri-allate 218-962-7 2303-17-5 S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate Tri-allate C10H16Cl3NOS CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Positive RMS: The United Kingdom Tri-allate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate 16Jul2009 2009 doi:10.2903/j.efsa.2009.181r
+Tri-allate 218-962-7 2303-17-5 single chemical entity Component is identical to the substance Tri-allate 218-962-7 2303-17-5 S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate Tri-allate C10H16Cl3NOS CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Positive RMS: The United Kingdom Tri-allate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate 16Jul2009 2009 doi:10.2903/j.efsa.2009.181r
+Tri-allate 218-962-7 2303-17-5 single chemical entity Component is identical to the substance Tri-allate 218-962-7 2303-17-5 S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate Tri-allate C10H16Cl3NOS CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Positive RMS: The United Kingdom Tri-allate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate 16Jul2009 2009 doi:10.2903/j.efsa.2009.181r
+Tri-allate 218-962-7 2303-17-5 single chemical entity Component is identical to the substance Tri-allate 218-962-7 2303-17-5 S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate Tri-allate C10H16Cl3NOS CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Positive RMS: The United Kingdom Tri-allate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate 16Jul2009 2009 doi:10.2903/j.efsa.2009.181r
+Tri-allate 218-962-7 2303-17-5 single chemical entity Component is identical to the substance Tri-allate 218-962-7 2303-17-5 S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate Tri-allate C10H16Cl3NOS CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Positive RMS: The United Kingdom Tri-allate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate 16Jul2009 2009 doi:10.2903/j.efsa.2009.181r
+Tri-allate 218-962-7 2303-17-5 single chemical entity Component is identical to the substance Tri-allate 218-962-7 2303-17-5 S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate Tri-allate C10H16Cl3NOS CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Tri-allate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate 16Jul2009 2009 doi:10.2903/j.efsa.2009.181r
+Tri-allate 218-962-7 2303-17-5 single chemical entity Component is identical to the substance Tri-allate 218-962-7 2303-17-5 S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate Tri-allate C10H16Cl3NOS CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Tri-allate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate 16Jul2009 2009 doi:10.2903/j.efsa.2009.181r
+Tri-allate 218-962-7 2303-17-5 single chemical entity Component is identical to the substance Tri-allate 218-962-7 2303-17-5 S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate Tri-allate C10H16Cl3NOS CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: The United Kingdom Tri-allate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate 16Jul2009 2009 doi:10.2903/j.efsa.2009.181r
+Tri-allate 218-962-7 2303-17-5 single chemical entity Component is identical to the substance Tri-allate 218-962-7 2303-17-5 S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate Tri-allate C10H16Cl3NOS CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: The United Kingdom Tri-allate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate 16Jul2009 2009 doi:10.2903/j.efsa.2009.181r
+Tri-allate 218-962-7 2303-17-5 single chemical entity Component is identical to the substance Tri-allate 218-962-7 2303-17-5 S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate Tri-allate C10H16Cl3NOS CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3 organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable House mouse (as animal) B6C3F1 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Tri-allate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate 16Jul2009 2009 doi:10.2903/j.efsa.2009.181r
+Tri-allate 218-962-7 2303-17-5 single chemical entity Component is identical to the substance Tri-allate 218-962-7 2303-17-5 S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate Tri-allate C10H16Cl3NOS CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3 organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Tri-allate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate 16Jul2009 2009 doi:10.2903/j.efsa.2009.181r
+Tri-allate 218-962-7 2303-17-5 single chemical entity Component is identical to the substance Tri-allate 218-962-7 2303-17-5 S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate Tri-allate C10H16Cl3NOS CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3 organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Hamster (as animal) CHO Not reported yes without Positive RMS: The United Kingdom Tri-allate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate 16Jul2009 2009 doi:10.2903/j.efsa.2009.181r
+Tri-allate 218-962-7 2303-17-5 single chemical entity Component is identical to the substance Tri-allate 218-962-7 2303-17-5 S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate Tri-allate C10H16Cl3NOS CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3 organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Hamster (as animal) CHO Not reported yes with Positive RMS: The United Kingdom Tri-allate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate 16Jul2009 2009 doi:10.2903/j.efsa.2009.181r
+Tri-allate 218-962-7 2303-17-5 single chemical entity Component is identical to the substance Tri-allate 218-962-7 2303-17-5 S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate Tri-allate C10H16Cl3NOS CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Crj:CD(SD) 6 Male oral: gavage 18.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Tri-allate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate 16Jul2009 2009 doi:10.2903/j.efsa.2009.181r
+Tri-allate 218-962-7 2303-17-5 single chemical entity Component is identical to the substance Tri-allate 218-962-7 2303-17-5 S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate Tri-allate C10H16Cl3NOS CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Crj:CD(SD) 6 Male oral: gavage 42.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Tri-allate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate 16Jul2009 2009 doi:10.2903/j.efsa.2009.181r
+Tri-allate 218-962-7 2303-17-5 single chemical entity Component is identical to the substance Tri-allate 218-962-7 2303-17-5 S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate Tri-allate C10H16Cl3NOS CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No data Acceptable Hamster (as animal) Syrian 44 Male/Female oral: feed 7.0000000000 week yes not applicable Negative RMS: The United Kingdom Tri-allate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate 16Jul2009 2009 doi:10.2903/j.efsa.2009.181r
+Tri-allate 218-962-7 2303-17-5 single chemical entity Component is identical to the substance Tri-allate 218-962-7 2303-17-5 S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate Tri-allate C10H16Cl3NOS CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No data Acceptable Hamster (as animal) Syrian 44 Male/Female oral: feed 14.0000000000 week yes not applicable Negative RMS: The United Kingdom Tri-allate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate 16Jul2009 2009 doi:10.2903/j.efsa.2009.181r
+Tri-allate 218-962-7 2303-17-5 single chemical entity Component is identical to the substance Tri-allate 218-962-7 2303-17-5 S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate Tri-allate C10H16Cl3NOS CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female oral: unspecified 72.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: The United Kingdom Tri-allate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate 16Jul2009 2009 doi:10.2903/j.efsa.2009.181r
+Tri-allate 218-962-7 2303-17-5 single chemical entity Component is identical to the substance Tri-allate 218-962-7 2303-17-5 S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate Tri-allate C10H16Cl3NOS CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female oral: unspecified 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: The United Kingdom Tri-allate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate 16Jul2009 2009 doi:10.2903/j.efsa.2009.181r
+Tri-allate 218-962-7 2303-17-5 single chemical entity Component is identical to the substance Tri-allate 218-962-7 2303-17-5 S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate Tri-allate C10H16Cl3NOS CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: The United Kingdom Tri-allate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate 16Jul2009 2009 doi:10.2903/j.efsa.2009.181r
+Tri-allate 218-962-7 2303-17-5 single chemical entity Component is identical to the substance Tri-allate 218-962-7 2303-17-5 S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate Tri-allate C10H16Cl3NOS CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3 organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo Equivalent or similar to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) Yes Acceptable House mouse (as animal) B6C3F1 6 Male oral: gavage 16.0000000000 h yes not applicable Negative RMS: The United Kingdom Tri-allate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate 16Jul2009 2009 doi:10.2903/j.efsa.2009.181r
+Tri-allate 218-962-7 2303-17-5 single chemical entity Component is identical to the substance Tri-allate 218-962-7 2303-17-5 S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate Tri-allate C10H16Cl3NOS CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3 organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo Equivalent or similar to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) Yes Acceptable House mouse (as animal) B6C3F1 6 Male oral: gavage 2.0000000000 h yes not applicable Negative RMS: The United Kingdom Tri-allate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate 16Jul2009 2009 doi:10.2903/j.efsa.2009.181r
+Tri-allate 218-962-7 2303-17-5 single chemical entity Component is a metabolite of the substance 2,3,3-trichloroprop-2-ene-sulfonic acid 2,3,3-trichloroprop-2-ene-1-sulfonic acid Not in list C3H3Cl3O3S C(C(=C(Cl)Cl)Cl)S(=O)(=O)O InChI=1S/C3H3Cl3O3S/c4-2(3(5)6)1-10(7,8)9/h1H2,(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes with Negative RMS: The United Kingdom Tri-allate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate 16Jul2009 2009 doi:10.2903/j.efsa.2009.181r
+Tri-allate 218-962-7 2303-17-5 single chemical entity Component is a metabolite of the substance 2,3,3-trichloroprop-2-ene-sulfonic acid 2,3,3-trichloroprop-2-ene-1-sulfonic acid Not in list C3H3Cl3O3S C(C(=C(Cl)Cl)Cl)S(=O)(=O)O InChI=1S/C3H3Cl3O3S/c4-2(3(5)6)1-10(7,8)9/h1H2,(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The United Kingdom Tri-allate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate 16Jul2009 2009 doi:10.2903/j.efsa.2009.181r
+Tri-allate 218-962-7 2303-17-5 single chemical entity Component is a metabolite of the substance 2,3,3-trichloroprop-2-ene-sulfonic acid 2,3,3-trichloroprop-2-ene-1-sulfonic acid Not in list C3H3Cl3O3S C(C(=C(Cl)Cl)Cl)S(=O)(=O)O InChI=1S/C3H3Cl3O3S/c4-2(3(5)6)1-10(7,8)9/h1H2,(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes without Negative RMS: The United Kingdom Tri-allate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate 16Jul2009 2009 doi:10.2903/j.efsa.2009.181r
+Tri-allate 218-962-7 2303-17-5 single chemical entity Component is a metabolite of the substance 2,3,3-trichloroprop-2-ene-sulfonic acid 2,3,3-trichloroprop-2-ene-1-sulfonic acid Not in list C3H3Cl3O3S C(C(=C(Cl)Cl)Cl)S(=O)(=O)O InChI=1S/C3H3Cl3O3S/c4-2(3(5)6)1-10(7,8)9/h1H2,(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The United Kingdom Tri-allate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate 16Jul2009 2009 doi:10.2903/j.efsa.2009.181r
+Tri-allate 218-962-7 2303-17-5 single chemical entity Component is a metabolite of the substance 2,3,3-trichloroprop-2-ene-sulfonic acid 2,3,3-trichloroprop-2-ene-1-sulfonic acid Not in list C3H3Cl3O3S C(C(=C(Cl)Cl)Cl)S(=O)(=O)O InChI=1S/C3H3Cl3O3S/c4-2(3(5)6)1-10(7,8)9/h1H2,(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The United Kingdom Tri-allate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate 16Jul2009 2009 doi:10.2903/j.efsa.2009.181r
+Tri-allate 218-962-7 2303-17-5 single chemical entity Component is a metabolite of the substance 2,3,3-trichloroprop-2-ene-sulfonic acid 2,3,3-trichloroprop-2-ene-1-sulfonic acid Not in list C3H3Cl3O3S C(C(=C(Cl)Cl)Cl)S(=O)(=O)O InChI=1S/C3H3Cl3O3S/c4-2(3(5)6)1-10(7,8)9/h1H2,(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The United Kingdom Tri-allate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate 16Jul2009 2009 doi:10.2903/j.efsa.2009.181r
+Tri-allate 218-962-7 2303-17-5 single chemical entity Component is a metabolite of the substance 2,3,3-trichloroprop-2-ene-sulfonic acid 2,3,3-trichloroprop-2-ene-1-sulfonic acid Not in list C3H3Cl3O3S C(C(=C(Cl)Cl)Cl)S(=O)(=O)O InChI=1S/C3H3Cl3O3S/c4-2(3(5)6)1-10(7,8)9/h1H2,(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The United Kingdom Tri-allate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate 16Jul2009 2009 doi:10.2903/j.efsa.2009.181r
+Tri-allate 218-962-7 2303-17-5 single chemical entity Component is a metabolite of the substance 2,3,3-trichloroprop-2-ene-sulfonic acid 2,3,3-trichloroprop-2-ene-1-sulfonic acid Not in list C3H3Cl3O3S C(C(=C(Cl)Cl)Cl)S(=O)(=O)O InChI=1S/C3H3Cl3O3S/c4-2(3(5)6)1-10(7,8)9/h1H2,(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The United Kingdom Tri-allate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate 16Jul2009 2009 doi:10.2903/j.efsa.2009.181r
+Tri-allate 218-962-7 2303-17-5 single chemical entity Component is a metabolite of the substance 2,3,3-trichloroprop-2-ene-sulfonic acid 2,3,3-trichloroprop-2-ene-1-sulfonic acid Not in list C3H3Cl3O3S C(C(=C(Cl)Cl)Cl)S(=O)(=O)O InChI=1S/C3H3Cl3O3S/c4-2(3(5)6)1-10(7,8)9/h1H2,(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The United Kingdom Tri-allate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate 16Jul2009 2009 doi:10.2903/j.efsa.2009.181r
+Tri-allate 218-962-7 2303-17-5 single chemical entity Component is a metabolite of the substance 2,3,3-trichloroprop-2-ene-sulfonic acid 2,3,3-trichloroprop-2-ene-1-sulfonic acid Not in list C3H3Cl3O3S C(C(=C(Cl)Cl)Cl)S(=O)(=O)O InChI=1S/C3H3Cl3O3S/c4-2(3(5)6)1-10(7,8)9/h1H2,(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The United Kingdom Tri-allate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate 16Jul2009 2009 doi:10.2903/j.efsa.2009.181r
+Tri-allate 218-962-7 2303-17-5 single chemical entity Component is a metabolite of the substance 2,3,3-trichloroprop-2-ene-sulfonic acid 2,3,3-trichloroprop-2-ene-1-sulfonic acid Not in list C3H3Cl3O3S C(C(=C(Cl)Cl)Cl)S(=O)(=O)O InChI=1S/C3H3Cl3O3S/c4-2(3(5)6)1-10(7,8)9/h1H2,(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: The United Kingdom Tri-allate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate 16Jul2009 2009 doi:10.2903/j.efsa.2009.181r
+Tri-allate 218-962-7 2303-17-5 single chemical entity Component is a metabolite of the substance 2,3,3-trichloroprop-2-ene-sulfonic acid 2,3,3-trichloroprop-2-ene-1-sulfonic acid Not in list C3H3Cl3O3S C(C(=C(Cl)Cl)Cl)S(=O)(=O)O InChI=1S/C3H3Cl3O3S/c4-2(3(5)6)1-10(7,8)9/h1H2,(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Negative RMS: The United Kingdom Tri-allate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate 16Jul2009 2009 doi:10.2903/j.efsa.2009.181r
+Tri-allate 218-962-7 2303-17-5 single chemical entity Component is a metabolite of the substance 2,3,3-trichloroprop-2-ene-sulfonic acid 2,3,3-trichloroprop-2-ene-1-sulfonic acid Not in list C3H3Cl3O3S C(C(=C(Cl)Cl)Cl)S(=O)(=O)O InChI=1S/C3H3Cl3O3S/c4-2(3(5)6)1-10(7,8)9/h1H2,(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Negative no information RMS: The United Kingdom Tri-allate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate 16Jul2009 2009 doi:10.2903/j.efsa.2009.181r
+Tri-allate 218-962-7 2303-17-5 single chemical entity Component is a metabolite of the substance 2,3,3-trichloroprop-2-ene-sulfonic acid 2,3,3-trichloroprop-2-ene-1-sulfonic acid Not in list C3H3Cl3O3S C(C(=C(Cl)Cl)Cl)S(=O)(=O)O InChI=1S/C3H3Cl3O3S/c4-2(3(5)6)1-10(7,8)9/h1H2,(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative no information RMS: The United Kingdom Tri-allate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate 16Jul2009 2009 doi:10.2903/j.efsa.2009.181r
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is identical to the substance Thiencarbazone-methyl 317815-83-1 methyl 4-[(4,5-dihydro-3-methoxy-4-methyl-5-oxo-1H-1,2,4-triazol-1-yl)carboxamidosulfonyl]-5-methylthiophene-3-carboxylate Thiencarbazone-methyl C12H14N4O7S2 CC1=C(C(=CS1)C(=O)OC)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C InChI=1S/C12H14N4O7S2/c1-6-8(7(5-24-6)9(17)22-3)25(20,21)14-10(18)16-12(19)15(2)11(13-16)23-4/h5H,1-4H3,(H,14,18) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is identical to the substance Thiencarbazone-methyl 317815-83-1 methyl 4-[(4,5-dihydro-3-methoxy-4-methyl-5-oxo-1H-1,2,4-triazol-1-yl)carboxamidosulfonyl]-5-methylthiophene-3-carboxylate Thiencarbazone-methyl C12H14N4O7S2 CC1=C(C(=CS1)C(=O)OC)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C InChI=1S/C12H14N4O7S2/c1-6-8(7(5-24-6)9(17)22-3)25(20,21)14-10(18)16-12(19)15(2)11(13-16)23-4/h5H,1-4H3,(H,14,18) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is identical to the substance Thiencarbazone-methyl 317815-83-1 methyl 4-[(4,5-dihydro-3-methoxy-4-methyl-5-oxo-1H-1,2,4-triazol-1-yl)carboxamidosulfonyl]-5-methylthiophene-3-carboxylate Thiencarbazone-methyl C12H14N4O7S2 CC1=C(C(=CS1)C(=O)OC)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C InChI=1S/C12H14N4O7S2/c1-6-8(7(5-24-6)9(17)22-3)25(20,21)14-10(18)16-12(19)15(2)11(13-16)23-4/h5H,1-4H3,(H,14,18) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is identical to the substance Thiencarbazone-methyl 317815-83-1 methyl 4-[(4,5-dihydro-3-methoxy-4-methyl-5-oxo-1H-1,2,4-triazol-1-yl)carboxamidosulfonyl]-5-methylthiophene-3-carboxylate Thiencarbazone-methyl C12H14N4O7S2 CC1=C(C(=CS1)C(=O)OC)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C InChI=1S/C12H14N4O7S2/c1-6-8(7(5-24-6)9(17)22-3)25(20,21)14-10(18)16-12(19)15(2)11(13-16)23-4/h5H,1-4H3,(H,14,18) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is identical to the substance Thiencarbazone-methyl 317815-83-1 methyl 4-[(4,5-dihydro-3-methoxy-4-methyl-5-oxo-1H-1,2,4-triazol-1-yl)carboxamidosulfonyl]-5-methylthiophene-3-carboxylate Thiencarbazone-methyl C12H14N4O7S2 CC1=C(C(=CS1)C(=O)OC)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C InChI=1S/C12H14N4O7S2/c1-6-8(7(5-24-6)9(17)22-3)25(20,21)14-10(18)16-12(19)15(2)11(13-16)23-4/h5H,1-4H3,(H,14,18) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is identical to the substance Thiencarbazone-methyl 317815-83-1 methyl 4-[(4,5-dihydro-3-methoxy-4-methyl-5-oxo-1H-1,2,4-triazol-1-yl)carboxamidosulfonyl]-5-methylthiophene-3-carboxylate Thiencarbazone-methyl C12H14N4O7S2 CC1=C(C(=CS1)C(=O)OC)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C InChI=1S/C12H14N4O7S2/c1-6-8(7(5-24-6)9(17)22-3)25(20,21)14-10(18)16-12(19)15(2)11(13-16)23-4/h5H,1-4H3,(H,14,18) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is identical to the substance Thiencarbazone-methyl 317815-83-1 methyl 4-[(4,5-dihydro-3-methoxy-4-methyl-5-oxo-1H-1,2,4-triazol-1-yl)carboxamidosulfonyl]-5-methylthiophene-3-carboxylate Thiencarbazone-methyl C12H14N4O7S2 CC1=C(C(=CS1)C(=O)OC)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C InChI=1S/C12H14N4O7S2/c1-6-8(7(5-24-6)9(17)22-3)25(20,21)14-10(18)16-12(19)15(2)11(13-16)23-4/h5H,1-4H3,(H,14,18) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is identical to the substance Thiencarbazone-methyl 317815-83-1 methyl 4-[(4,5-dihydro-3-methoxy-4-methyl-5-oxo-1H-1,2,4-triazol-1-yl)carboxamidosulfonyl]-5-methylthiophene-3-carboxylate Thiencarbazone-methyl C12H14N4O7S2 CC1=C(C(=CS1)C(=O)OC)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C InChI=1S/C12H14N4O7S2/c1-6-8(7(5-24-6)9(17)22-3)25(20,21)14-10(18)16-12(19)15(2)11(13-16)23-4/h5H,1-4H3,(H,14,18) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is identical to the substance Thiencarbazone-methyl 317815-83-1 methyl 4-[(4,5-dihydro-3-methoxy-4-methyl-5-oxo-1H-1,2,4-triazol-1-yl)carboxamidosulfonyl]-5-methylthiophene-3-carboxylate Thiencarbazone-methyl C12H14N4O7S2 CC1=C(C(=CS1)C(=O)OC)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C InChI=1S/C12H14N4O7S2/c1-6-8(7(5-24-6)9(17)22-3)25(20,21)14-10(18)16-12(19)15(2)11(13-16)23-4/h5H,1-4H3,(H,14,18) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is identical to the substance Thiencarbazone-methyl 317815-83-1 methyl 4-[(4,5-dihydro-3-methoxy-4-methyl-5-oxo-1H-1,2,4-triazol-1-yl)carboxamidosulfonyl]-5-methylthiophene-3-carboxylate Thiencarbazone-methyl C12H14N4O7S2 CC1=C(C(=CS1)C(=O)OC)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C InChI=1S/C12H14N4O7S2/c1-6-8(7(5-24-6)9(17)22-3)25(20,21)14-10(18)16-12(19)15(2)11(13-16)23-4/h5H,1-4H3,(H,14,18) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is identical to the substance Thiencarbazone-methyl 317815-83-1 methyl 4-[(4,5-dihydro-3-methoxy-4-methyl-5-oxo-1H-1,2,4-triazol-1-yl)carboxamidosulfonyl]-5-methylthiophene-3-carboxylate Thiencarbazone-methyl C12H14N4O7S2 CC1=C(C(=CS1)C(=O)OC)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C InChI=1S/C12H14N4O7S2/c1-6-8(7(5-24-6)9(17)22-3)25(20,21)14-10(18)16-12(19)15(2)11(13-16)23-4/h5H,1-4H3,(H,14,18) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is identical to the substance Thiencarbazone-methyl 317815-83-1 methyl 4-[(4,5-dihydro-3-methoxy-4-methyl-5-oxo-1H-1,2,4-triazol-1-yl)carboxamidosulfonyl]-5-methylthiophene-3-carboxylate Thiencarbazone-methyl C12H14N4O7S2 CC1=C(C(=CS1)C(=O)OC)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C InChI=1S/C12H14N4O7S2/c1-6-8(7(5-24-6)9(17)22-3)25(20,21)14-10(18)16-12(19)15(2)11(13-16)23-4/h5H,1-4H3,(H,14,18) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is identical to the substance Thiencarbazone-methyl 317815-83-1 methyl 4-[(4,5-dihydro-3-methoxy-4-methyl-5-oxo-1H-1,2,4-triazol-1-yl)carboxamidosulfonyl]-5-methylthiophene-3-carboxylate Thiencarbazone-methyl C12H14N4O7S2 CC1=C(C(=CS1)C(=O)OC)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C InChI=1S/C12H14N4O7S2/c1-6-8(7(5-24-6)9(17)22-3)25(20,21)14-10(18)16-12(19)15(2)11(13-16)23-4/h5H,1-4H3,(H,14,18) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is identical to the substance Thiencarbazone-methyl 317815-83-1 methyl 4-[(4,5-dihydro-3-methoxy-4-methyl-5-oxo-1H-1,2,4-triazol-1-yl)carboxamidosulfonyl]-5-methylthiophene-3-carboxylate Thiencarbazone-methyl C12H14N4O7S2 CC1=C(C(=CS1)C(=O)OC)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C InChI=1S/C12H14N4O7S2/c1-6-8(7(5-24-6)9(17)22-3)25(20,21)14-10(18)16-12(19)15(2)11(13-16)23-4/h5H,1-4H3,(H,14,18) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is identical to the substance Thiencarbazone-methyl 317815-83-1 methyl 4-[(4,5-dihydro-3-methoxy-4-methyl-5-oxo-1H-1,2,4-triazol-1-yl)carboxamidosulfonyl]-5-methylthiophene-3-carboxylate Thiencarbazone-methyl C12H14N4O7S2 CC1=C(C(=CS1)C(=O)OC)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C InChI=1S/C12H14N4O7S2/c1-6-8(7(5-24-6)9(17)22-3)25(20,21)14-10(18)16-12(19)15(2)11(13-16)23-4/h5H,1-4H3,(H,14,18) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is identical to the substance Thiencarbazone-methyl 317815-83-1 methyl 4-[(4,5-dihydro-3-methoxy-4-methyl-5-oxo-1H-1,2,4-triazol-1-yl)carboxamidosulfonyl]-5-methylthiophene-3-carboxylate Thiencarbazone-methyl C12H14N4O7S2 CC1=C(C(=CS1)C(=O)OC)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C InChI=1S/C12H14N4O7S2/c1-6-8(7(5-24-6)9(17)22-3)25(20,21)14-10(18)16-12(19)15(2)11(13-16)23-4/h5H,1-4H3,(H,14,18) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is identical to the substance Thiencarbazone-methyl 317815-83-1 methyl 4-[(4,5-dihydro-3-methoxy-4-methyl-5-oxo-1H-1,2,4-triazol-1-yl)carboxamidosulfonyl]-5-methylthiophene-3-carboxylate Thiencarbazone-methyl C12H14N4O7S2 CC1=C(C(=CS1)C(=O)OC)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C InChI=1S/C12H14N4O7S2/c1-6-8(7(5-24-6)9(17)22-3)25(20,21)14-10(18)16-12(19)15(2)11(13-16)23-4/h5H,1-4H3,(H,14,18) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is identical to the substance Thiencarbazone-methyl 317815-83-1 methyl 4-[(4,5-dihydro-3-methoxy-4-methyl-5-oxo-1H-1,2,4-triazol-1-yl)carboxamidosulfonyl]-5-methylthiophene-3-carboxylate Thiencarbazone-methyl C12H14N4O7S2 CC1=C(C(=CS1)C(=O)OC)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C InChI=1S/C12H14N4O7S2/c1-6-8(7(5-24-6)9(17)22-3)25(20,21)14-10(18)16-12(19)15(2)11(13-16)23-4/h5H,1-4H3,(H,14,18) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is identical to the substance Thiencarbazone-methyl 317815-83-1 methyl 4-[(4,5-dihydro-3-methoxy-4-methyl-5-oxo-1H-1,2,4-triazol-1-yl)carboxamidosulfonyl]-5-methylthiophene-3-carboxylate Thiencarbazone-methyl C12H14N4O7S2 CC1=C(C(=CS1)C(=O)OC)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C InChI=1S/C12H14N4O7S2/c1-6-8(7(5-24-6)9(17)22-3)25(20,21)14-10(18)16-12(19)15(2)11(13-16)23-4/h5H,1-4H3,(H,14,18) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is identical to the substance Thiencarbazone-methyl 317815-83-1 methyl 4-[(4,5-dihydro-3-methoxy-4-methyl-5-oxo-1H-1,2,4-triazol-1-yl)carboxamidosulfonyl]-5-methylthiophene-3-carboxylate Thiencarbazone-methyl C12H14N4O7S2 CC1=C(C(=CS1)C(=O)OC)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C InChI=1S/C12H14N4O7S2/c1-6-8(7(5-24-6)9(17)22-3)25(20,21)14-10(18)16-12(19)15(2)11(13-16)23-4/h5H,1-4H3,(H,14,18) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is a metabolite of the substance 3-sulfamoylthiophene-2,4-dicarboxylic acid 3-sulfamoylthiophene-2,4-dicarboxylic acid Not in list C6H5NO6S2 O=S(N)(=O)c1c(scc1C(=O)O)C(O)=O InChI=1/C6H5NO6S2/c7-15(12,13)4-2(5(8)9)1-14-3(4)6(10)11/h1H,(H,8,9)(H,10,11)(H2,7,12,13) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is a metabolite of the substance 3-sulfamoylthiophene-2,4-dicarboxylic acid 3-sulfamoylthiophene-2,4-dicarboxylic acid Not in list C6H5NO6S2 O=S(N)(=O)c1c(scc1C(=O)O)C(O)=O InChI=1/C6H5NO6S2/c7-15(12,13)4-2(5(8)9)1-14-3(4)6(10)11/h1H,(H,8,9)(H,10,11)(H2,7,12,13) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is identical to the substance Thiencarbazone-methyl 317815-83-1 methyl 4-[(4,5-dihydro-3-methoxy-4-methyl-5-oxo-1H-1,2,4-triazol-1-yl)carboxamidosulfonyl]-5-methylthiophene-3-carboxylate Thiencarbazone-methyl C12H14N4O7S2 CC1=C(C(=CS1)C(=O)OC)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C InChI=1S/C12H14N4O7S2/c1-6-8(7(5-24-6)9(17)22-3)25(20,21)14-10(18)16-12(19)15(2)11(13-16)23-4/h5H,1-4H3,(H,14,18) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is identical to the substance Thiencarbazone-methyl 317815-83-1 methyl 4-[(4,5-dihydro-3-methoxy-4-methyl-5-oxo-1H-1,2,4-triazol-1-yl)carboxamidosulfonyl]-5-methylthiophene-3-carboxylate Thiencarbazone-methyl C12H14N4O7S2 CC1=C(C(=CS1)C(=O)OC)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C InChI=1S/C12H14N4O7S2/c1-6-8(7(5-24-6)9(17)22-3)25(20,21)14-10(18)16-12(19)15(2)11(13-16)23-4/h5H,1-4H3,(H,14,18) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is identical to the substance Thiencarbazone-methyl 317815-83-1 methyl 4-[(4,5-dihydro-3-methoxy-4-methyl-5-oxo-1H-1,2,4-triazol-1-yl)carboxamidosulfonyl]-5-methylthiophene-3-carboxylate Thiencarbazone-methyl C12H14N4O7S2 CC1=C(C(=CS1)C(=O)OC)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C InChI=1S/C12H14N4O7S2/c1-6-8(7(5-24-6)9(17)22-3)25(20,21)14-10(18)16-12(19)15(2)11(13-16)23-4/h5H,1-4H3,(H,14,18) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is identical to the substance Thiencarbazone-methyl 317815-83-1 methyl 4-[(4,5-dihydro-3-methoxy-4-methyl-5-oxo-1H-1,2,4-triazol-1-yl)carboxamidosulfonyl]-5-methylthiophene-3-carboxylate Thiencarbazone-methyl C12H14N4O7S2 CC1=C(C(=CS1)C(=O)OC)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C InChI=1S/C12H14N4O7S2/c1-6-8(7(5-24-6)9(17)22-3)25(20,21)14-10(18)16-12(19)15(2)11(13-16)23-4/h5H,1-4H3,(H,14,18) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is a metabolite of the substance 3-sulfamoylthiophene-2,4-dicarboxylic acid 3-sulfamoylthiophene-2,4-dicarboxylic acid Not in list C6H5NO6S2 O=S(N)(=O)c1c(scc1C(=O)O)C(O)=O InChI=1/C6H5NO6S2/c7-15(12,13)4-2(5(8)9)1-14-3(4)6(10)11/h1H,(H,8,9)(H,10,11)(H2,7,12,13) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is a metabolite of the substance 3-sulfamoylthiophene-2,4-dicarboxylic acid 3-sulfamoylthiophene-2,4-dicarboxylic acid Not in list C6H5NO6S2 O=S(N)(=O)c1c(scc1C(=O)O)C(O)=O InChI=1/C6H5NO6S2/c7-15(12,13)4-2(5(8)9)1-14-3(4)6(10)11/h1H,(H,8,9)(H,10,11)(H2,7,12,13) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is a metabolite of the substance 3-sulfamoylthiophene-2,4-dicarboxylic acid 3-sulfamoylthiophene-2,4-dicarboxylic acid Not in list C6H5NO6S2 O=S(N)(=O)c1c(scc1C(=O)O)C(O)=O InChI=1/C6H5NO6S2/c7-15(12,13)4-2(5(8)9)1-14-3(4)6(10)11/h1H,(H,8,9)(H,10,11)(H2,7,12,13) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 6 Male/Female intraperitoneal 24.0000000000 h yes not applicable Negative no evidence RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is a metabolite of the substance 4-{[(3-methoxy-4-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]sulfamoyl}-5-methylthiophene-3-carboxylic acid 4-[(3-methoxy-4-methyl-5-oxo-1,2,4-triazole-1-carbonyl)sulfamoyl]-5-methylthiophene-3-carboxylic acid Not in list C11H12N4O7S2 CC1=C(C(=CS1)C(=O)O)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C InChI=1S/C11H12N4O7S2/c1-5-7(6(4-23-5)8(16)17)24(20,21)13-9(18)15-11(19)14(2)10(12-15)22-3/h4H,1-3H3,(H,13,18)(H,16,17) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is a metabolite of the substance 4-{[(3-methoxy-4-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]sulfamoyl}-5-methylthiophene-3-carboxylic acid 4-[(3-methoxy-4-methyl-5-oxo-1,2,4-triazole-1-carbonyl)sulfamoyl]-5-methylthiophene-3-carboxylic acid Not in list C11H12N4O7S2 CC1=C(C(=CS1)C(=O)O)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C InChI=1S/C11H12N4O7S2/c1-5-7(6(4-23-5)8(16)17)24(20,21)13-9(18)15-11(19)14(2)10(12-15)22-3/h4H,1-3H3,(H,13,18)(H,16,17) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is a metabolite of the substance 4-{[(3-methoxy-4-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]sulfamoyl}-5-methylthiophene-3-carboxylic acid 4-[(3-methoxy-4-methyl-5-oxo-1,2,4-triazole-1-carbonyl)sulfamoyl]-5-methylthiophene-3-carboxylic acid Not in list C11H12N4O7S2 CC1=C(C(=CS1)C(=O)O)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C InChI=1S/C11H12N4O7S2/c1-5-7(6(4-23-5)8(16)17)24(20,21)13-9(18)15-11(19)14(2)10(12-15)22-3/h4H,1-3H3,(H,13,18)(H,16,17) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is a metabolite of the substance 4-{[(3-methoxy-4-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]sulfamoyl}-5-methylthiophene-3-carboxylic acid 4-[(3-methoxy-4-methyl-5-oxo-1,2,4-triazole-1-carbonyl)sulfamoyl]-5-methylthiophene-3-carboxylic acid Not in list C11H12N4O7S2 CC1=C(C(=CS1)C(=O)O)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C InChI=1S/C11H12N4O7S2/c1-5-7(6(4-23-5)8(16)17)24(20,21)13-9(18)15-11(19)14(2)10(12-15)22-3/h4H,1-3H3,(H,13,18)(H,16,17) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is a metabolite of the substance 4-{[(3-methoxy-4-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]sulfamoyl}-5-methylthiophene-3-carboxylic acid 4-[(3-methoxy-4-methyl-5-oxo-1,2,4-triazole-1-carbonyl)sulfamoyl]-5-methylthiophene-3-carboxylic acid Not in list C11H12N4O7S2 CC1=C(C(=CS1)C(=O)O)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C InChI=1S/C11H12N4O7S2/c1-5-7(6(4-23-5)8(16)17)24(20,21)13-9(18)15-11(19)14(2)10(12-15)22-3/h4H,1-3H3,(H,13,18)(H,16,17) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is a metabolite of the substance 4-{[(3-methoxy-4-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]sulfamoyl}-5-methylthiophene-3-carboxylic acid 4-[(3-methoxy-4-methyl-5-oxo-1,2,4-triazole-1-carbonyl)sulfamoyl]-5-methylthiophene-3-carboxylic acid Not in list C11H12N4O7S2 CC1=C(C(=CS1)C(=O)O)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C InChI=1S/C11H12N4O7S2/c1-5-7(6(4-23-5)8(16)17)24(20,21)13-9(18)15-11(19)14(2)10(12-15)22-3/h4H,1-3H3,(H,13,18)(H,16,17) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is a metabolite of the substance 4-{[(3-methoxy-4-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]sulfamoyl}-5-methylthiophene-3-carboxylic acid 4-[(3-methoxy-4-methyl-5-oxo-1,2,4-triazole-1-carbonyl)sulfamoyl]-5-methylthiophene-3-carboxylic acid Not in list C11H12N4O7S2 CC1=C(C(=CS1)C(=O)O)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C InChI=1S/C11H12N4O7S2/c1-5-7(6(4-23-5)8(16)17)24(20,21)13-9(18)15-11(19)14(2)10(12-15)22-3/h4H,1-3H3,(H,13,18)(H,16,17) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is a metabolite of the substance 4-{[(3-methoxy-4-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]sulfamoyl}-5-methylthiophene-3-carboxylic acid 4-[(3-methoxy-4-methyl-5-oxo-1,2,4-triazole-1-carbonyl)sulfamoyl]-5-methylthiophene-3-carboxylic acid Not in list C11H12N4O7S2 CC1=C(C(=CS1)C(=O)O)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C InChI=1S/C11H12N4O7S2/c1-5-7(6(4-23-5)8(16)17)24(20,21)13-9(18)15-11(19)14(2)10(12-15)22-3/h4H,1-3H3,(H,13,18)(H,16,17) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is a metabolite of the substance 4-{[(3-methoxy-4-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]sulfamoyl}-5-methylthiophene-3-carboxylic acid 4-[(3-methoxy-4-methyl-5-oxo-1,2,4-triazole-1-carbonyl)sulfamoyl]-5-methylthiophene-3-carboxylic acid Not in list C11H12N4O7S2 CC1=C(C(=CS1)C(=O)O)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C InChI=1S/C11H12N4O7S2/c1-5-7(6(4-23-5)8(16)17)24(20,21)13-9(18)15-11(19)14(2)10(12-15)22-3/h4H,1-3H3,(H,13,18)(H,16,17) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is a metabolite of the substance 4-{[(3-methoxy-4-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]sulfamoyl}-5-methylthiophene-3-carboxylic acid 4-[(3-methoxy-4-methyl-5-oxo-1,2,4-triazole-1-carbonyl)sulfamoyl]-5-methylthiophene-3-carboxylic acid Not in list C11H12N4O7S2 CC1=C(C(=CS1)C(=O)O)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C InChI=1S/C11H12N4O7S2/c1-5-7(6(4-23-5)8(16)17)24(20,21)13-9(18)15-11(19)14(2)10(12-15)22-3/h4H,1-3H3,(H,13,18)(H,16,17) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is a metabolite of the substance 4-{[(3-methoxy-4-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]sulfamoyl}-5-methylthiophene-3-carboxylic acid 4-[(3-methoxy-4-methyl-5-oxo-1,2,4-triazole-1-carbonyl)sulfamoyl]-5-methylthiophene-3-carboxylic acid Not in list C11H12N4O7S2 CC1=C(C(=CS1)C(=O)O)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C InChI=1S/C11H12N4O7S2/c1-5-7(6(4-23-5)8(16)17)24(20,21)13-9(18)15-11(19)14(2)10(12-15)22-3/h4H,1-3H3,(H,13,18)(H,16,17) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is a metabolite of the substance 4-{[(3-methoxy-4-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]sulfamoyl}-5-methylthiophene-3-carboxylic acid 4-[(3-methoxy-4-methyl-5-oxo-1,2,4-triazole-1-carbonyl)sulfamoyl]-5-methylthiophene-3-carboxylic acid Not in list C11H12N4O7S2 CC1=C(C(=CS1)C(=O)O)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C InChI=1S/C11H12N4O7S2/c1-5-7(6(4-23-5)8(16)17)24(20,21)13-9(18)15-11(19)14(2)10(12-15)22-3/h4H,1-3H3,(H,13,18)(H,16,17) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is a metabolite of the substance 4-{[(3-methoxy-4-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]sulfamoyl}-5-methylthiophene-3-carboxylic acid 4-[(3-methoxy-4-methyl-5-oxo-1,2,4-triazole-1-carbonyl)sulfamoyl]-5-methylthiophene-3-carboxylic acid Not in list C11H12N4O7S2 CC1=C(C(=CS1)C(=O)O)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C InChI=1S/C11H12N4O7S2/c1-5-7(6(4-23-5)8(16)17)24(20,21)13-9(18)15-11(19)14(2)10(12-15)22-3/h4H,1-3H3,(H,13,18)(H,16,17) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is a metabolite of the substance 4-{[(3-methoxy-4-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]sulfamoyl}-5-methylthiophene-3-carboxylic acid 4-[(3-methoxy-4-methyl-5-oxo-1,2,4-triazole-1-carbonyl)sulfamoyl]-5-methylthiophene-3-carboxylic acid Not in list C11H12N4O7S2 CC1=C(C(=CS1)C(=O)O)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C InChI=1S/C11H12N4O7S2/c1-5-7(6(4-23-5)8(16)17)24(20,21)13-9(18)15-11(19)14(2)10(12-15)22-3/h4H,1-3H3,(H,13,18)(H,16,17) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is a metabolite of the substance methyl 5-methyl-4-sulfamoylthiophene-3-carboxylate methyl 5-methyl-4-sulfamoylthiophene-3-carboxylate Not in list C7H9NO4S2 O=S(N)(=O)c1c(C)scc1C(=O)OC InChI=1/C7H9NO4S2/c1-4-6(14(8,10)11)5(3-13-4)7(9)12-2/h3H,1-2H3,(H2,8,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is a metabolite of the substance methyl 5-methyl-4-sulfamoylthiophene-3-carboxylate methyl 5-methyl-4-sulfamoylthiophene-3-carboxylate Not in list C7H9NO4S2 O=S(N)(=O)c1c(C)scc1C(=O)OC InChI=1/C7H9NO4S2/c1-4-6(14(8,10)11)5(3-13-4)7(9)12-2/h3H,1-2H3,(H2,8,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is a metabolite of the substance methyl 5-methyl-4-sulfamoylthiophene-3-carboxylate methyl 5-methyl-4-sulfamoylthiophene-3-carboxylate Not in list C7H9NO4S2 O=S(N)(=O)c1c(C)scc1C(=O)OC InChI=1/C7H9NO4S2/c1-4-6(14(8,10)11)5(3-13-4)7(9)12-2/h3H,1-2H3,(H2,8,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is a metabolite of the substance methyl 5-methyl-4-sulfamoylthiophene-3-carboxylate methyl 5-methyl-4-sulfamoylthiophene-3-carboxylate Not in list C7H9NO4S2 O=S(N)(=O)c1c(C)scc1C(=O)OC InChI=1/C7H9NO4S2/c1-4-6(14(8,10)11)5(3-13-4)7(9)12-2/h3H,1-2H3,(H2,8,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is a metabolite of the substance methyl 5-methyl-4-sulfamoylthiophene-3-carboxylate methyl 5-methyl-4-sulfamoylthiophene-3-carboxylate Not in list C7H9NO4S2 O=S(N)(=O)c1c(C)scc1C(=O)OC InChI=1/C7H9NO4S2/c1-4-6(14(8,10)11)5(3-13-4)7(9)12-2/h3H,1-2H3,(H2,8,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is a metabolite of the substance methyl 5-methyl-4-sulfamoylthiophene-3-carboxylate methyl 5-methyl-4-sulfamoylthiophene-3-carboxylate Not in list C7H9NO4S2 O=S(N)(=O)c1c(C)scc1C(=O)OC InChI=1/C7H9NO4S2/c1-4-6(14(8,10)11)5(3-13-4)7(9)12-2/h3H,1-2H3,(H2,8,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is a metabolite of the substance methyl 5-methyl-4-sulfamoylthiophene-3-carboxylate methyl 5-methyl-4-sulfamoylthiophene-3-carboxylate Not in list C7H9NO4S2 O=S(N)(=O)c1c(C)scc1C(=O)OC InChI=1/C7H9NO4S2/c1-4-6(14(8,10)11)5(3-13-4)7(9)12-2/h3H,1-2H3,(H2,8,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is a metabolite of the substance methyl 5-methyl-4-sulfamoylthiophene-3-carboxylate methyl 5-methyl-4-sulfamoylthiophene-3-carboxylate Not in list C7H9NO4S2 O=S(N)(=O)c1c(C)scc1C(=O)OC InChI=1/C7H9NO4S2/c1-4-6(14(8,10)11)5(3-13-4)7(9)12-2/h3H,1-2H3,(H2,8,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is a metabolite of the substance methyl 5-methyl-4-sulfamoylthiophene-3-carboxylate methyl 5-methyl-4-sulfamoylthiophene-3-carboxylate Not in list C7H9NO4S2 O=S(N)(=O)c1c(C)scc1C(=O)OC InChI=1/C7H9NO4S2/c1-4-6(14(8,10)11)5(3-13-4)7(9)12-2/h3H,1-2H3,(H2,8,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is a metabolite of the substance methyl 5-methyl-4-sulfamoylthiophene-3-carboxylate methyl 5-methyl-4-sulfamoylthiophene-3-carboxylate Not in list C7H9NO4S2 O=S(N)(=O)c1c(C)scc1C(=O)OC InChI=1/C7H9NO4S2/c1-4-6(14(8,10)11)5(3-13-4)7(9)12-2/h3H,1-2H3,(H2,8,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is a metabolite of the substance methyl 4-({[(3-methoxy-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]amino}sulfonyl)-5-methylthiophene-3-carboxylate methyl 4-{[(3-methoxy-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]sulfamoyl}-5-methylthiophene-3-carboxylate Not in list C11H12N4O7S2 O=S(=O)(NC(=O)N1/N=C(/OC)NC1=O)c2c(C)scc2C(=O)OC InChI=1/C11H12N4O7S2/c1-5-7(6(4-23-5)8(16)21-2)24(19,20)14-11(18)15-10(17)12-9(13-15)22-3/h4H,1-3H3,(H,14,18)(H,12,13,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is a metabolite of the substance methyl 4-({[(3-methoxy-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]amino}sulfonyl)-5-methylthiophene-3-carboxylate methyl 4-{[(3-methoxy-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]sulfamoyl}-5-methylthiophene-3-carboxylate Not in list C11H12N4O7S2 O=S(=O)(NC(=O)N1/N=C(/OC)NC1=O)c2c(C)scc2C(=O)OC InChI=1/C11H12N4O7S2/c1-5-7(6(4-23-5)8(16)21-2)24(19,20)14-11(18)15-10(17)12-9(13-15)22-3/h4H,1-3H3,(H,14,18)(H,12,13,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is a metabolite of the substance methyl 4-({[(3-methoxy-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]amino}sulfonyl)-5-methylthiophene-3-carboxylate methyl 4-{[(3-methoxy-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]sulfamoyl}-5-methylthiophene-3-carboxylate Not in list C11H12N4O7S2 O=S(=O)(NC(=O)N1/N=C(/OC)NC1=O)c2c(C)scc2C(=O)OC InChI=1/C11H12N4O7S2/c1-5-7(6(4-23-5)8(16)21-2)24(19,20)14-11(18)15-10(17)12-9(13-15)22-3/h4H,1-3H3,(H,14,18)(H,12,13,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is a metabolite of the substance methyl 4-({[(3-methoxy-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]amino}sulfonyl)-5-methylthiophene-3-carboxylate methyl 4-{[(3-methoxy-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]sulfamoyl}-5-methylthiophene-3-carboxylate Not in list C11H12N4O7S2 O=S(=O)(NC(=O)N1/N=C(/OC)NC1=O)c2c(C)scc2C(=O)OC InChI=1/C11H12N4O7S2/c1-5-7(6(4-23-5)8(16)21-2)24(19,20)14-11(18)15-10(17)12-9(13-15)22-3/h4H,1-3H3,(H,14,18)(H,12,13,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is a metabolite of the substance methyl 4-({[(3-methoxy-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]amino}sulfonyl)-5-methylthiophene-3-carboxylate methyl 4-{[(3-methoxy-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]sulfamoyl}-5-methylthiophene-3-carboxylate Not in list C11H12N4O7S2 O=S(=O)(NC(=O)N1/N=C(/OC)NC1=O)c2c(C)scc2C(=O)OC InChI=1/C11H12N4O7S2/c1-5-7(6(4-23-5)8(16)21-2)24(19,20)14-11(18)15-10(17)12-9(13-15)22-3/h4H,1-3H3,(H,14,18)(H,12,13,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is a metabolite of the substance methyl 4-({[(3-methoxy-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]amino}sulfonyl)-5-methylthiophene-3-carboxylate methyl 4-{[(3-methoxy-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]sulfamoyl}-5-methylthiophene-3-carboxylate Not in list C11H12N4O7S2 O=S(=O)(NC(=O)N1/N=C(/OC)NC1=O)c2c(C)scc2C(=O)OC InChI=1/C11H12N4O7S2/c1-5-7(6(4-23-5)8(16)21-2)24(19,20)14-11(18)15-10(17)12-9(13-15)22-3/h4H,1-3H3,(H,14,18)(H,12,13,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is a metabolite of the substance methyl 4-({[(3-methoxy-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]amino}sulfonyl)-5-methylthiophene-3-carboxylate methyl 4-{[(3-methoxy-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]sulfamoyl}-5-methylthiophene-3-carboxylate Not in list C11H12N4O7S2 O=S(=O)(NC(=O)N1/N=C(/OC)NC1=O)c2c(C)scc2C(=O)OC InChI=1/C11H12N4O7S2/c1-5-7(6(4-23-5)8(16)21-2)24(19,20)14-11(18)15-10(17)12-9(13-15)22-3/h4H,1-3H3,(H,14,18)(H,12,13,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is a metabolite of the substance methyl 4-({[(3-methoxy-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]amino}sulfonyl)-5-methylthiophene-3-carboxylate methyl 4-{[(3-methoxy-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]sulfamoyl}-5-methylthiophene-3-carboxylate Not in list C11H12N4O7S2 O=S(=O)(NC(=O)N1/N=C(/OC)NC1=O)c2c(C)scc2C(=O)OC InChI=1/C11H12N4O7S2/c1-5-7(6(4-23-5)8(16)21-2)24(19,20)14-11(18)15-10(17)12-9(13-15)22-3/h4H,1-3H3,(H,14,18)(H,12,13,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is a metabolite of the substance methyl 4-({[(3-methoxy-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]amino}sulfonyl)-5-methylthiophene-3-carboxylate methyl 4-{[(3-methoxy-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]sulfamoyl}-5-methylthiophene-3-carboxylate Not in list C11H12N4O7S2 O=S(=O)(NC(=O)N1/N=C(/OC)NC1=O)c2c(C)scc2C(=O)OC InChI=1/C11H12N4O7S2/c1-5-7(6(4-23-5)8(16)21-2)24(19,20)14-11(18)15-10(17)12-9(13-15)22-3/h4H,1-3H3,(H,14,18)(H,12,13,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is a metabolite of the substance methyl 4-({[(3-methoxy-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]amino}sulfonyl)-5-methylthiophene-3-carboxylate methyl 4-{[(3-methoxy-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]sulfamoyl}-5-methylthiophene-3-carboxylate Not in list C11H12N4O7S2 O=S(=O)(NC(=O)N1/N=C(/OC)NC1=O)c2c(C)scc2C(=O)OC InChI=1/C11H12N4O7S2/c1-5-7(6(4-23-5)8(16)21-2)24(19,20)14-11(18)15-10(17)12-9(13-15)22-3/h4H,1-3H3,(H,14,18)(H,12,13,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is a metabolite of the substance methyl 4-({[(3-methoxy-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]amino}sulfonyl)-5-methylthiophene-3-carboxylate methyl 4-{[(3-methoxy-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]sulfamoyl}-5-methylthiophene-3-carboxylate Not in list C11H12N4O7S2 O=S(=O)(NC(=O)N1/N=C(/OC)NC1=O)c2c(C)scc2C(=O)OC InChI=1/C11H12N4O7S2/c1-5-7(6(4-23-5)8(16)21-2)24(19,20)14-11(18)15-10(17)12-9(13-15)22-3/h4H,1-3H3,(H,14,18)(H,12,13,17) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is a metabolite of the substance methyl 4-({[(3-methoxy-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]amino}sulfonyl)-5-methylthiophene-3-carboxylate methyl 4-{[(3-methoxy-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]sulfamoyl}-5-methylthiophene-3-carboxylate Not in list C11H12N4O7S2 O=S(=O)(NC(=O)N1/N=C(/OC)NC1=O)c2c(C)scc2C(=O)OC InChI=1/C11H12N4O7S2/c1-5-7(6(4-23-5)8(16)21-2)24(19,20)14-11(18)15-10(17)12-9(13-15)22-3/h4H,1-3H3,(H,14,18)(H,12,13,17) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is a metabolite of the substance methyl 4-({[(3-methoxy-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]amino}sulfonyl)-5-methylthiophene-3-carboxylate methyl 4-{[(3-methoxy-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]sulfamoyl}-5-methylthiophene-3-carboxylate Not in list C11H12N4O7S2 O=S(=O)(NC(=O)N1/N=C(/OC)NC1=O)c2c(C)scc2C(=O)OC InChI=1/C11H12N4O7S2/c1-5-7(6(4-23-5)8(16)21-2)24(19,20)14-11(18)15-10(17)12-9(13-15)22-3/h4H,1-3H3,(H,14,18)(H,12,13,17) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Thiencarbazone-methyl 317815-83-1 single chemical entity Component is a metabolite of the substance methyl 4-({[(3-methoxy-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]amino}sulfonyl)-5-methylthiophene-3-carboxylate methyl 4-{[(3-methoxy-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]sulfamoyl}-5-methylthiophene-3-carboxylate Not in list C11H12N4O7S2 O=S(=O)(NC(=O)N1/N=C(/OC)NC1=O)c2c(C)scc2C(=O)OC InChI=1/C11H12N4O7S2/c1-5-7(6(4-23-5)8(16)21-2)24(19,20)14-11(18)15-10(17)12-9(13-15)22-3/h4H,1-3H3,(H,14,18)(H,12,13,17) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thiencarbazone-methyl (BYH 18636) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl 01Jul2013 2013 doi:10.2903/j.efsa.2013.3270
+Triflumuron 264-980-3 64628-44-0 single chemical entity Component is identical to the substance Triflumuron 264-980-3 64628-44-0 2-chloro-N-{[4-(trifluoromethoxy)phenyl]carbamoyl}benzamide Triflumuron C15H10ClF3N2O3 O=C(C1=CC=CC=C1Cl)NC(NC(C=C2)=CC=C2OC(F)(F)F)=O InChI=1S/C15H10ClF3N2O3/c16-12-4-2-1-3-11(12)13(22)21-14(23)20-9-5-7-10(8-6-9)24-15(17,18)19/h1-8H,(H2,20,21,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Italy Triflumuron (Addendum 2 ) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron 03Jan2011 2011 doi:10.2903/j.efsa.2011.1941
+Triflumuron 264-980-3 64628-44-0 single chemical entity Component is identical to the substance Triflumuron 264-980-3 64628-44-0 2-chloro-N-{[4-(trifluoromethoxy)phenyl]carbamoyl}benzamide Triflumuron C15H10ClF3N2O3 O=C(C1=CC=CC=C1Cl)NC(NC(C=C2)=CC=C2OC(F)(F)F)=O InChI=1S/C15H10ClF3N2O3/c16-12-4-2-1-3-11(12)13(22)21-14(23)20-9-5-7-10(8-6-9)24-15(17,18)19/h1-8H,(H2,20,21,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Italy Triflumuron (Addendum 2 ) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron 03Jan2011 2011 doi:10.2903/j.efsa.2011.1941
+Triflumuron 264-980-3 64628-44-0 single chemical entity Component is identical to the substance Triflumuron 264-980-3 64628-44-0 2-chloro-N-{[4-(trifluoromethoxy)phenyl]carbamoyl}benzamide Triflumuron C15H10ClF3N2O3 O=C(C1=CC=CC=C1Cl)NC(NC(C=C2)=CC=C2OC(F)(F)F)=O InChI=1S/C15H10ClF3N2O3/c16-12-4-2-1-3-11(12)13(22)21-14(23)20-9-5-7-10(8-6-9)24-15(17,18)19/h1-8H,(H2,20,21,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Italy Triflumuron (Addendum 2 ) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron 03Jan2011 2011 doi:10.2903/j.efsa.2011.1941
+Triflumuron 264-980-3 64628-44-0 single chemical entity Component is identical to the substance Triflumuron 264-980-3 64628-44-0 2-chloro-N-{[4-(trifluoromethoxy)phenyl]carbamoyl}benzamide Triflumuron C15H10ClF3N2O3 O=C(C1=CC=CC=C1Cl)NC(NC(C=C2)=CC=C2OC(F)(F)F)=O InChI=1S/C15H10ClF3N2O3/c16-12-4-2-1-3-11(12)13(22)21-14(23)20-9-5-7-10(8-6-9)24-15(17,18)19/h1-8H,(H2,20,21,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Italy Triflumuron (Addendum 2 ) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron 03Jan2011 2011 doi:10.2903/j.efsa.2011.1941
+Triflumuron 264-980-3 64628-44-0 single chemical entity Component is identical to the substance Triflumuron 264-980-3 64628-44-0 2-chloro-N-{[4-(trifluoromethoxy)phenyl]carbamoyl}benzamide Triflumuron C15H10ClF3N2O3 O=C(C1=CC=CC=C1Cl)NC(NC(C=C2)=CC=C2OC(F)(F)F)=O InChI=1S/C15H10ClF3N2O3/c16-12-4-2-1-3-11(12)13(22)21-14(23)20-9-5-7-10(8-6-9)24-15(17,18)19/h1-8H,(H2,20,21,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Italy Triflumuron (Addendum 2 ) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron 03Jan2011 2011 doi:10.2903/j.efsa.2011.1941
+Triflumuron 264-980-3 64628-44-0 single chemical entity Component is identical to the substance Triflumuron 264-980-3 64628-44-0 2-chloro-N-{[4-(trifluoromethoxy)phenyl]carbamoyl}benzamide Triflumuron C15H10ClF3N2O3 O=C(C1=CC=CC=C1Cl)NC(NC(C=C2)=CC=C2OC(F)(F)F)=O InChI=1S/C15H10ClF3N2O3/c16-12-4-2-1-3-11(12)13(22)21-14(23)20-9-5-7-10(8-6-9)24-15(17,18)19/h1-8H,(H2,20,21,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Italy Triflumuron (Addendum 2 ) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron 03Jan2011 2011 doi:10.2903/j.efsa.2011.1941
+Triflumuron 264-980-3 64628-44-0 single chemical entity Component is identical to the substance Triflumuron 264-980-3 64628-44-0 2-chloro-N-{[4-(trifluoromethoxy)phenyl]carbamoyl}benzamide Triflumuron C15H10ClF3N2O3 O=C(C1=CC=CC=C1Cl)NC(NC(C=C2)=CC=C2OC(F)(F)F)=O InChI=1S/C15H10ClF3N2O3/c16-12-4-2-1-3-11(12)13(22)21-14(23)20-9-5-7-10(8-6-9)24-15(17,18)19/h1-8H,(H2,20,21,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Italy Triflumuron (Addendum 2 ) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron 03Jan2011 2011 doi:10.2903/j.efsa.2011.1941
+Triflumuron 264-980-3 64628-44-0 single chemical entity Component is identical to the substance Triflumuron 264-980-3 64628-44-0 2-chloro-N-{[4-(trifluoromethoxy)phenyl]carbamoyl}benzamide Triflumuron C15H10ClF3N2O3 O=C(C1=CC=CC=C1Cl)NC(NC(C=C2)=CC=C2OC(F)(F)F)=O InChI=1S/C15H10ClF3N2O3/c16-12-4-2-1-3-11(12)13(22)21-14(23)20-9-5-7-10(8-6-9)24-15(17,18)19/h1-8H,(H2,20,21,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Italy Triflumuron (Addendum 2 ) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron 03Jan2011 2011 doi:10.2903/j.efsa.2011.1941
+Triflumuron 264-980-3 64628-44-0 single chemical entity Component is identical to the substance Triflumuron 264-980-3 64628-44-0 2-chloro-N-{[4-(trifluoromethoxy)phenyl]carbamoyl}benzamide Triflumuron C15H10ClF3N2O3 O=C(C1=CC=CC=C1Cl)NC(NC(C=C2)=CC=C2OC(F)(F)F)=O InChI=1S/C15H10ClF3N2O3/c16-12-4-2-1-3-11(12)13(22)21-14(23)20-9-5-7-10(8-6-9)24-15(17,18)19/h1-8H,(H2,20,21,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Italy Triflumuron (Addendum 2 ) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron 03Jan2011 2011 doi:10.2903/j.efsa.2011.1941
+Triflumuron 264-980-3 64628-44-0 single chemical entity Component is identical to the substance Triflumuron 264-980-3 64628-44-0 2-chloro-N-{[4-(trifluoromethoxy)phenyl]carbamoyl}benzamide Triflumuron C15H10ClF3N2O3 O=C(C1=CC=CC=C1Cl)NC(NC(C=C2)=CC=C2OC(F)(F)F)=O InChI=1S/C15H10ClF3N2O3/c16-12-4-2-1-3-11(12)13(22)21-14(23)20-9-5-7-10(8-6-9)24-15(17,18)19/h1-8H,(H2,20,21,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Italy Triflumuron (Addendum 2 ) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron 03Jan2011 2011 doi:10.2903/j.efsa.2011.1941
+Triflumuron 264-980-3 64628-44-0 single chemical entity Component is identical to the substance Triflumuron 264-980-3 64628-44-0 2-chloro-N-{[4-(trifluoromethoxy)phenyl]carbamoyl}benzamide Triflumuron C15H10ClF3N2O3 O=C(C1=CC=CC=C1Cl)NC(NC(C=C2)=CC=C2OC(F)(F)F)=O InChI=1S/C15H10ClF3N2O3/c16-12-4-2-1-3-11(12)13(22)21-14(23)20-9-5-7-10(8-6-9)24-15(17,18)19/h1-8H,(H2,20,21,22,23) organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Italy Triflumuron (Addendum 2 ) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron 03Jan2011 2011 doi:10.2903/j.efsa.2011.1941
+Triflumuron 264-980-3 64628-44-0 single chemical entity Component is identical to the substance Triflumuron 264-980-3 64628-44-0 2-chloro-N-{[4-(trifluoromethoxy)phenyl]carbamoyl}benzamide Triflumuron C15H10ClF3N2O3 O=C(C1=CC=CC=C1Cl)NC(NC(C=C2)=CC=C2OC(F)(F)F)=O InChI=1S/C15H10ClF3N2O3/c16-12-4-2-1-3-11(12)13(22)21-14(23)20-9-5-7-10(8-6-9)24-15(17,18)19/h1-8H,(H2,20,21,22,23) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Italy Triflumuron (Addendum 2 ) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron 03Jan2011 2011 doi:10.2903/j.efsa.2011.1941
+Triflumuron 264-980-3 64628-44-0 single chemical entity Component is identical to the substance Triflumuron 264-980-3 64628-44-0 2-chloro-N-{[4-(trifluoromethoxy)phenyl]carbamoyl}benzamide Triflumuron C15H10ClF3N2O3 O=C(C1=CC=CC=C1Cl)NC(NC(C=C2)=CC=C2OC(F)(F)F)=O InChI=1S/C15H10ClF3N2O3/c16-12-4-2-1-3-11(12)13(22)21-14(23)20-9-5-7-10(8-6-9)24-15(17,18)19/h1-8H,(H2,20,21,22,23) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Italy Triflumuron (Addendum 2 ) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron 03Jan2011 2011 doi:10.2903/j.efsa.2011.1941
+Triflumuron 264-980-3 64628-44-0 single chemical entity Component is identical to the substance Triflumuron 264-980-3 64628-44-0 2-chloro-N-{[4-(trifluoromethoxy)phenyl]carbamoyl}benzamide Triflumuron C15H10ClF3N2O3 O=C(C1=CC=CC=C1Cl)NC(NC(C=C2)=CC=C2OC(F)(F)F)=O InChI=1S/C15H10ClF3N2O3/c16-12-4-2-1-3-11(12)13(22)21-14(23)20-9-5-7-10(8-6-9)24-15(17,18)19/h1-8H,(H2,20,21,22,23) organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro According to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: Italy Triflumuron (Addendum 2 ) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron 03Jan2011 2011 doi:10.2903/j.efsa.2011.1941
+Triflumuron 264-980-3 64628-44-0 single chemical entity Component is identical to the substance Triflumuron 264-980-3 64628-44-0 2-chloro-N-{[4-(trifluoromethoxy)phenyl]carbamoyl}benzamide Triflumuron C15H10ClF3N2O3 O=C(C1=CC=CC=C1Cl)NC(NC(C=C2)=CC=C2OC(F)(F)F)=O InChI=1S/C15H10ClF3N2O3/c16-12-4-2-1-3-11(12)13(22)21-14(23)20-9-5-7-10(8-6-9)24-15(17,18)19/h1-8H,(H2,20,21,22,23) organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro According to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: Italy Triflumuron (Addendum 2 ) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron 03Jan2011 2011 doi:10.2903/j.efsa.2011.1941
+Triflumuron 264-980-3 64628-44-0 single chemical entity Component is identical to the substance Triflumuron 264-980-3 64628-44-0 2-chloro-N-{[4-(trifluoromethoxy)phenyl]carbamoyl}benzamide Triflumuron C15H10ClF3N2O3 O=C(C1=CC=CC=C1Cl)NC(NC(C=C2)=CC=C2OC(F)(F)F)=O InChI=1S/C15H10ClF3N2O3/c16-12-4-2-1-3-11(12)13(22)21-14(23)20-9-5-7-10(8-6-9)24-15(17,18)19/h1-8H,(H2,20,21,22,23) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: Italy Triflumuron (Addendum 2 ) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron 03Jan2011 2011 doi:10.2903/j.efsa.2011.1941
+Triflumuron 264-980-3 64628-44-0 single chemical entity Component is identical to the substance Triflumuron 264-980-3 64628-44-0 2-chloro-N-{[4-(trifluoromethoxy)phenyl]carbamoyl}benzamide Triflumuron C15H10ClF3N2O3 O=C(C1=CC=CC=C1Cl)NC(NC(C=C2)=CC=C2OC(F)(F)F)=O InChI=1S/C15H10ClF3N2O3/c16-12-4-2-1-3-11(12)13(22)21-14(23)20-9-5-7-10(8-6-9)24-15(17,18)19/h1-8H,(H2,20,21,22,23) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: Italy Triflumuron (Addendum 2 ) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron 03Jan2011 2011 doi:10.2903/j.efsa.2011.1941
+Triflumuron 264-980-3 64628-44-0 single chemical entity Component is identical to the substance Triflumuron 264-980-3 64628-44-0 2-chloro-N-{[4-(trifluoromethoxy)phenyl]carbamoyl}benzamide Triflumuron C15H10ClF3N2O3 O=C(C1=CC=CC=C1Cl)NC(NC(C=C2)=CC=C2OC(F)(F)F)=O InChI=1S/C15H10ClF3N2O3/c16-12-4-2-1-3-11(12)13(22)21-14(23)20-9-5-7-10(8-6-9)24-15(17,18)19/h1-8H,(H2,20,21,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Italy Triflumuron (Addendum 2 ) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron 03Jan2011 2011 doi:10.2903/j.efsa.2011.1941
+Triflumuron 264-980-3 64628-44-0 single chemical entity Component is identical to the substance Triflumuron 264-980-3 64628-44-0 2-chloro-N-{[4-(trifluoromethoxy)phenyl]carbamoyl}benzamide Triflumuron C15H10ClF3N2O3 O=C(C1=CC=CC=C1Cl)NC(NC(C=C2)=CC=C2OC(F)(F)F)=O InChI=1S/C15H10ClF3N2O3/c16-12-4-2-1-3-11(12)13(22)21-14(23)20-9-5-7-10(8-6-9)24-15(17,18)19/h1-8H,(H2,20,21,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Italy Triflumuron (Addendum 2 ) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron 03Jan2011 2011 doi:10.2903/j.efsa.2011.1941
+Triflumuron 264-980-3 64628-44-0 single chemical entity Component is identical to the substance Triflumuron 264-980-3 64628-44-0 2-chloro-N-{[4-(trifluoromethoxy)phenyl]carbamoyl}benzamide Triflumuron C15H10ClF3N2O3 O=C(C1=CC=CC=C1Cl)NC(NC(C=C2)=CC=C2OC(F)(F)F)=O InChI=1S/C15H10ClF3N2O3/c16-12-4-2-1-3-11(12)13(22)21-14(23)20-9-5-7-10(8-6-9)24-15(17,18)19/h1-8H,(H2,20,21,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Italy Triflumuron (Addendum 2 ) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron 03Jan2011 2011 doi:10.2903/j.efsa.2011.1941
+Triflumuron 264-980-3 64628-44-0 single chemical entity Component is identical to the substance Triflumuron 264-980-3 64628-44-0 2-chloro-N-{[4-(trifluoromethoxy)phenyl]carbamoyl}benzamide Triflumuron C15H10ClF3N2O3 O=C(C1=CC=CC=C1Cl)NC(NC(C=C2)=CC=C2OC(F)(F)F)=O InChI=1S/C15H10ClF3N2O3/c16-12-4-2-1-3-11(12)13(22)21-14(23)20-9-5-7-10(8-6-9)24-15(17,18)19/h1-8H,(H2,20,21,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Italy Triflumuron (Addendum 2 ) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron 03Jan2011 2011 doi:10.2903/j.efsa.2011.1941
+Triflumuron 264-980-3 64628-44-0 single chemical entity Component is identical to the substance Triflumuron 264-980-3 64628-44-0 2-chloro-N-{[4-(trifluoromethoxy)phenyl]carbamoyl}benzamide Triflumuron C15H10ClF3N2O3 O=C(C1=CC=CC=C1Cl)NC(NC(C=C2)=CC=C2OC(F)(F)F)=O InChI=1S/C15H10ClF3N2O3/c16-12-4-2-1-3-11(12)13(22)21-14(23)20-9-5-7-10(8-6-9)24-15(17,18)19/h1-8H,(H2,20,21,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Italy Triflumuron (Addendum 2 ) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron 03Jan2011 2011 doi:10.2903/j.efsa.2011.1941
+Triflumuron 264-980-3 64628-44-0 single chemical entity Component is identical to the substance Triflumuron 264-980-3 64628-44-0 2-chloro-N-{[4-(trifluoromethoxy)phenyl]carbamoyl}benzamide Triflumuron C15H10ClF3N2O3 O=C(C1=CC=CC=C1Cl)NC(NC(C=C2)=CC=C2OC(F)(F)F)=O InChI=1S/C15H10ClF3N2O3/c16-12-4-2-1-3-11(12)13(22)21-14(23)20-9-5-7-10(8-6-9)24-15(17,18)19/h1-8H,(H2,20,21,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Italy Triflumuron (Addendum 2 ) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron 03Jan2011 2011 doi:10.2903/j.efsa.2011.1941
+Triflumuron 264-980-3 64628-44-0 single chemical entity Component is identical to the substance Triflumuron 264-980-3 64628-44-0 2-chloro-N-{[4-(trifluoromethoxy)phenyl]carbamoyl}benzamide Triflumuron C15H10ClF3N2O3 O=C(C1=CC=CC=C1Cl)NC(NC(C=C2)=CC=C2OC(F)(F)F)=O InChI=1S/C15H10ClF3N2O3/c16-12-4-2-1-3-11(12)13(22)21-14(23)20-9-5-7-10(8-6-9)24-15(17,18)19/h1-8H,(H2,20,21,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Italy Triflumuron (Addendum 2 ) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron 03Jan2011 2011 doi:10.2903/j.efsa.2011.1941
+Triflumuron 264-980-3 64628-44-0 single chemical entity Component is identical to the substance Triflumuron 264-980-3 64628-44-0 2-chloro-N-{[4-(trifluoromethoxy)phenyl]carbamoyl}benzamide Triflumuron C15H10ClF3N2O3 O=C(C1=CC=CC=C1Cl)NC(NC(C=C2)=CC=C2OC(F)(F)F)=O InChI=1S/C15H10ClF3N2O3/c16-12-4-2-1-3-11(12)13(22)21-14(23)20-9-5-7-10(8-6-9)24-15(17,18)19/h1-8H,(H2,20,21,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Italy Triflumuron (Addendum 2 ) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron 03Jan2011 2011 doi:10.2903/j.efsa.2011.1941
+Triflumuron 264-980-3 64628-44-0 single chemical entity Component is identical to the substance Triflumuron 264-980-3 64628-44-0 2-chloro-N-{[4-(trifluoromethoxy)phenyl]carbamoyl}benzamide Triflumuron C15H10ClF3N2O3 O=C(C1=CC=CC=C1Cl)NC(NC(C=C2)=CC=C2OC(F)(F)F)=O InChI=1S/C15H10ClF3N2O3/c16-12-4-2-1-3-11(12)13(22)21-14(23)20-9-5-7-10(8-6-9)24-15(17,18)19/h1-8H,(H2,20,21,22,23) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Italy Triflumuron (Addendum 2 ) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron 03Jan2011 2011 doi:10.2903/j.efsa.2011.1941
+Triflumuron 264-980-3 64628-44-0 single chemical entity Component is identical to the substance Triflumuron 264-980-3 64628-44-0 2-chloro-N-{[4-(trifluoromethoxy)phenyl]carbamoyl}benzamide Triflumuron C15H10ClF3N2O3 O=C(C1=CC=CC=C1Cl)NC(NC(C=C2)=CC=C2OC(F)(F)F)=O InChI=1S/C15H10ClF3N2O3/c16-12-4-2-1-3-11(12)13(22)21-14(23)20-9-5-7-10(8-6-9)24-15(17,18)19/h1-8H,(H2,20,21,22,23) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Italy Triflumuron (Addendum 2 ) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron 03Jan2011 2011 doi:10.2903/j.efsa.2011.1941
+Triflumuron 264-980-3 64628-44-0 single chemical entity Component is identical to the substance Triflumuron 264-980-3 64628-44-0 2-chloro-N-{[4-(trifluoromethoxy)phenyl]carbamoyl}benzamide Triflumuron C15H10ClF3N2O3 O=C(C1=CC=CC=C1Cl)NC(NC(C=C2)=CC=C2OC(F)(F)F)=O InChI=1S/C15H10ClF3N2O3/c16-12-4-2-1-3-11(12)13(22)21-14(23)20-9-5-7-10(8-6-9)24-15(17,18)19/h1-8H,(H2,20,21,22,23) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI Male/Female oral: unspecified 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Italy Triflumuron (Addendum 2 ) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron 03Jan2011 2011 doi:10.2903/j.efsa.2011.1941
+Triflumuron 264-980-3 64628-44-0 single chemical entity Component is identical to the substance Triflumuron 264-980-3 64628-44-0 2-chloro-N-{[4-(trifluoromethoxy)phenyl]carbamoyl}benzamide Triflumuron C15H10ClF3N2O3 O=C(C1=CC=CC=C1Cl)NC(NC(C=C2)=CC=C2OC(F)(F)F)=O InChI=1S/C15H10ClF3N2O3/c16-12-4-2-1-3-11(12)13(22)21-14(23)20-9-5-7-10(8-6-9)24-15(17,18)19/h1-8H,(H2,20,21,22,23) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI Male/Female oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Italy Triflumuron (Addendum 2 ) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron 03Jan2011 2011 doi:10.2903/j.efsa.2011.1941
+Triflumuron 264-980-3 64628-44-0 single chemical entity Component is a metabolite of the substance 4-Trifluoro-methoxyaniline 207-317-5 461-82-5 4-(Trifluoromethoxy)aniline 4-Trifluoro-methoxyaniline C7H6F3NO C1=CC(=CC=C1N)OC(F)(F)F InChI=1S/C7H6F3NO/c8-7(9,10)12-6-3-1-5(11)2-4-6/h1-4H,11H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Italy Triflumuron (Addendum 2 ) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron 03Jan2011 2011 doi:10.2903/j.efsa.2011.1941
+Triflumuron 264-980-3 64628-44-0 single chemical entity Component is a metabolite of the substance 4-Trifluoro-methoxyaniline 207-317-5 461-82-5 4-(Trifluoromethoxy)aniline 4-Trifluoro-methoxyaniline C7H6F3NO C1=CC(=CC=C1N)OC(F)(F)F InChI=1S/C7H6F3NO/c8-7(9,10)12-6-3-1-5(11)2-4-6/h1-4H,11H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Italy Triflumuron (Addendum 2 ) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron 03Jan2011 2011 doi:10.2903/j.efsa.2011.1941
+Triflumuron 264-980-3 64628-44-0 single chemical entity Component is a metabolite of the substance 4-Trifluoro-methoxyaniline 207-317-5 461-82-5 4-(Trifluoromethoxy)aniline 4-Trifluoro-methoxyaniline C7H6F3NO C1=CC(=CC=C1N)OC(F)(F)F InChI=1S/C7H6F3NO/c8-7(9,10)12-6-3-1-5(11)2-4-6/h1-4H,11H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Italy Triflumuron (Addendum 2 ) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron 03Jan2011 2011 doi:10.2903/j.efsa.2011.1941
+Triflumuron 264-980-3 64628-44-0 single chemical entity Component is a metabolite of the substance 4-Trifluoro-methoxyaniline 207-317-5 461-82-5 4-(Trifluoromethoxy)aniline 4-Trifluoro-methoxyaniline C7H6F3NO C1=CC(=CC=C1N)OC(F)(F)F InChI=1S/C7H6F3NO/c8-7(9,10)12-6-3-1-5(11)2-4-6/h1-4H,11H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Italy Triflumuron (Addendum 2 ) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron 03Jan2011 2011 doi:10.2903/j.efsa.2011.1941
+Triflumuron 264-980-3 64628-44-0 single chemical entity Component is a metabolite of the substance 4-Trifluoro-methoxyaniline 207-317-5 461-82-5 4-(Trifluoromethoxy)aniline 4-Trifluoro-methoxyaniline C7H6F3NO C1=CC(=CC=C1N)OC(F)(F)F InChI=1S/C7H6F3NO/c8-7(9,10)12-6-3-1-5(11)2-4-6/h1-4H,11H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Italy Triflumuron (Addendum 2 ) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron 03Jan2011 2011 doi:10.2903/j.efsa.2011.1941
+Triflumuron 264-980-3 64628-44-0 single chemical entity Component is a metabolite of the substance 4-Trifluoro-methoxyaniline 207-317-5 461-82-5 4-(Trifluoromethoxy)aniline 4-Trifluoro-methoxyaniline C7H6F3NO C1=CC(=CC=C1N)OC(F)(F)F InChI=1S/C7H6F3NO/c8-7(9,10)12-6-3-1-5(11)2-4-6/h1-4H,11H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Italy Triflumuron (Addendum 2 ) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron 03Jan2011 2011 doi:10.2903/j.efsa.2011.1941
+Triflumuron 264-980-3 64628-44-0 single chemical entity Component is a metabolite of the substance 4-Trifluoro-methoxyaniline 207-317-5 461-82-5 4-(Trifluoromethoxy)aniline 4-Trifluoro-methoxyaniline C7H6F3NO C1=CC(=CC=C1N)OC(F)(F)F InChI=1S/C7H6F3NO/c8-7(9,10)12-6-3-1-5(11)2-4-6/h1-4H,11H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Italy Triflumuron (Addendum 2 ) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron 03Jan2011 2011 doi:10.2903/j.efsa.2011.1941
+Triflumuron 264-980-3 64628-44-0 single chemical entity Component is a metabolite of the substance 4-Trifluoro-methoxyaniline 207-317-5 461-82-5 4-(Trifluoromethoxy)aniline 4-Trifluoro-methoxyaniline C7H6F3NO C1=CC(=CC=C1N)OC(F)(F)F InChI=1S/C7H6F3NO/c8-7(9,10)12-6-3-1-5(11)2-4-6/h1-4H,11H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Italy Triflumuron (Addendum 2 ) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron 03Jan2011 2011 doi:10.2903/j.efsa.2011.1941
+Famoxadone 603-520-1 131807-57-3 single chemical entity Component is identical to the substance Famoxadone 603-520-1 131807-57-3 3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione Famoxadone C22H18N2O4 CC1(C(=O)N(C(=O)O1)NC2=CC=CC=C2)C3=CC=C(C=C3)OC4=CC=CC=C4 InChI=1S/C22H18N2O4/c1-22(16-12-14-19(15-13-16)27-18-10-6-3-7-11-18)20(25)24(21(26)28-22)23-17-8-4-2-5-9-17/h2-15,23H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Famoxadone (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance famoxadone 16Jul2015 2015 doi:10.2903/j.efsa.2015.4194
+Famoxadone 603-520-1 131807-57-3 single chemical entity Component is identical to the substance Famoxadone 603-520-1 131807-57-3 3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione Famoxadone C22H18N2O4 CC1(C(=O)N(C(=O)O1)NC2=CC=CC=C2)C3=CC=C(C=C3)OC4=CC=CC=C4 InChI=1S/C22H18N2O4/c1-22(16-12-14-19(15-13-16)27-18-10-6-3-7-11-18)20(25)24(21(26)28-22)23-17-8-4-2-5-9-17/h2-15,23H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Famoxadone (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance famoxadone 16Jul2015 2015 doi:10.2903/j.efsa.2015.4194
+Famoxadone 603-520-1 131807-57-3 single chemical entity Component is identical to the substance Famoxadone 603-520-1 131807-57-3 3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione Famoxadone C22H18N2O4 CC1(C(=O)N(C(=O)O1)NC2=CC=CC=C2)C3=CC=C(C=C3)OC4=CC=CC=C4 InChI=1S/C22H18N2O4/c1-22(16-12-14-19(15-13-16)27-18-10-6-3-7-11-18)20(25)24(21(26)28-22)23-17-8-4-2-5-9-17/h2-15,23H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Famoxadone (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance famoxadone 16Jul2015 2015 doi:10.2903/j.efsa.2015.4194
+Famoxadone 603-520-1 131807-57-3 single chemical entity Component is identical to the substance Famoxadone 603-520-1 131807-57-3 3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione Famoxadone C22H18N2O4 CC1(C(=O)N(C(=O)O1)NC2=CC=CC=C2)C3=CC=C(C=C3)OC4=CC=CC=C4 InChI=1S/C22H18N2O4/c1-22(16-12-14-19(15-13-16)27-18-10-6-3-7-11-18)20(25)24(21(26)28-22)23-17-8-4-2-5-9-17/h2-15,23H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Famoxadone (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance famoxadone 16Jul2015 2015 doi:10.2903/j.efsa.2015.4194
+Famoxadone 603-520-1 131807-57-3 single chemical entity Component is identical to the substance Famoxadone 603-520-1 131807-57-3 3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione Famoxadone C22H18N2O4 CC1(C(=O)N(C(=O)O1)NC2=CC=CC=C2)C3=CC=C(C=C3)OC4=CC=CC=C4 InChI=1S/C22H18N2O4/c1-22(16-12-14-19(15-13-16)27-18-10-6-3-7-11-18)20(25)24(21(26)28-22)23-17-8-4-2-5-9-17/h2-15,23H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Famoxadone (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance famoxadone 16Jul2015 2015 doi:10.2903/j.efsa.2015.4194
+Famoxadone 603-520-1 131807-57-3 single chemical entity Component is identical to the substance Famoxadone 603-520-1 131807-57-3 3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione Famoxadone C22H18N2O4 CC1(C(=O)N(C(=O)O1)NC2=CC=CC=C2)C3=CC=C(C=C3)OC4=CC=CC=C4 InChI=1S/C22H18N2O4/c1-22(16-12-14-19(15-13-16)27-18-10-6-3-7-11-18)20(25)24(21(26)28-22)23-17-8-4-2-5-9-17/h2-15,23H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Famoxadone (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance famoxadone 16Jul2015 2015 doi:10.2903/j.efsa.2015.4194
+Famoxadone 603-520-1 131807-57-3 single chemical entity Component is identical to the substance Famoxadone 603-520-1 131807-57-3 3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione Famoxadone C22H18N2O4 CC1(C(=O)N(C(=O)O1)NC2=CC=CC=C2)C3=CC=C(C=C3)OC4=CC=CC=C4 InChI=1S/C22H18N2O4/c1-22(16-12-14-19(15-13-16)27-18-10-6-3-7-11-18)20(25)24(21(26)28-22)23-17-8-4-2-5-9-17/h2-15,23H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Famoxadone (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance famoxadone 16Jul2015 2015 doi:10.2903/j.efsa.2015.4194
+Famoxadone 603-520-1 131807-57-3 single chemical entity Component is identical to the substance Famoxadone 603-520-1 131807-57-3 3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione Famoxadone C22H18N2O4 CC1(C(=O)N(C(=O)O1)NC2=CC=CC=C2)C3=CC=C(C=C3)OC4=CC=CC=C4 InChI=1S/C22H18N2O4/c1-22(16-12-14-19(15-13-16)27-18-10-6-3-7-11-18)20(25)24(21(26)28-22)23-17-8-4-2-5-9-17/h2-15,23H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Famoxadone (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance famoxadone 16Jul2015 2015 doi:10.2903/j.efsa.2015.4194
+Famoxadone 603-520-1 131807-57-3 single chemical entity Component is identical to the substance Famoxadone 603-520-1 131807-57-3 3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione Famoxadone C22H18N2O4 CC1(C(=O)N(C(=O)O1)NC2=CC=CC=C2)C3=CC=C(C=C3)OC4=CC=CC=C4 InChI=1S/C22H18N2O4/c1-22(16-12-14-19(15-13-16)27-18-10-6-3-7-11-18)20(25)24(21(26)28-22)23-17-8-4-2-5-9-17/h2-15,23H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Famoxadone (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance famoxadone 16Jul2015 2015 doi:10.2903/j.efsa.2015.4194
+Famoxadone 603-520-1 131807-57-3 single chemical entity Component is identical to the substance Famoxadone 603-520-1 131807-57-3 3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione Famoxadone C22H18N2O4 CC1(C(=O)N(C(=O)O1)NC2=CC=CC=C2)C3=CC=C(C=C3)OC4=CC=CC=C4 InChI=1S/C22H18N2O4/c1-22(16-12-14-19(15-13-16)27-18-10-6-3-7-11-18)20(25)24(21(26)28-22)23-17-8-4-2-5-9-17/h2-15,23H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Famoxadone (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance famoxadone 16Jul2015 2015 doi:10.2903/j.efsa.2015.4194
+Famoxadone 603-520-1 131807-57-3 single chemical entity Component is identical to the substance Famoxadone 603-520-1 131807-57-3 3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione Famoxadone C22H18N2O4 CC1(C(=O)N(C(=O)O1)NC2=CC=CC=C2)C3=CC=C(C=C3)OC4=CC=CC=C4 InChI=1S/C22H18N2O4/c1-22(16-12-14-19(15-13-16)27-18-10-6-3-7-11-18)20(25)24(21(26)28-22)23-17-8-4-2-5-9-17/h2-15,23H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: The United Kingdom Famoxadone (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance famoxadone 16Jul2015 2015 doi:10.2903/j.efsa.2015.4194
+Famoxadone 603-520-1 131807-57-3 single chemical entity Component is identical to the substance Famoxadone 603-520-1 131807-57-3 3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione Famoxadone C22H18N2O4 CC1(C(=O)N(C(=O)O1)NC2=CC=CC=C2)C3=CC=C(C=C3)OC4=CC=CC=C4 InChI=1S/C22H18N2O4/c1-22(16-12-14-19(15-13-16)27-18-10-6-3-7-11-18)20(25)24(21(26)28-22)23-17-8-4-2-5-9-17/h2-15,23H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: The United Kingdom Famoxadone (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance famoxadone 16Jul2015 2015 doi:10.2903/j.efsa.2015.4194
+Famoxadone 603-520-1 131807-57-3 single chemical entity Component is identical to the substance Famoxadone 603-520-1 131807-57-3 3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione Famoxadone C22H18N2O4 CC1(C(=O)N(C(=O)O1)NC2=CC=CC=C2)C3=CC=C(C=C3)OC4=CC=CC=C4 InChI=1S/C22H18N2O4/c1-22(16-12-14-19(15-13-16)27-18-10-6-3-7-11-18)20(25)24(21(26)28-22)23-17-8-4-2-5-9-17/h2-15,23H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: The United Kingdom Famoxadone (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance famoxadone 16Jul2015 2015 doi:10.2903/j.efsa.2015.4194
+Famoxadone 603-520-1 131807-57-3 single chemical entity Component is identical to the substance Famoxadone 603-520-1 131807-57-3 3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione Famoxadone C22H18N2O4 CC1(C(=O)N(C(=O)O1)NC2=CC=CC=C2)C3=CC=C(C=C3)OC4=CC=CC=C4 InChI=1S/C22H18N2O4/c1-22(16-12-14-19(15-13-16)27-18-10-6-3-7-11-18)20(25)24(21(26)28-22)23-17-8-4-2-5-9-17/h2-15,23H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: The United Kingdom Famoxadone (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance famoxadone 16Jul2015 2015 doi:10.2903/j.efsa.2015.4194
+Famoxadone 603-520-1 131807-57-3 single chemical entity Component is identical to the substance Famoxadone 603-520-1 131807-57-3 3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione Famoxadone C22H18N2O4 CC1(C(=O)N(C(=O)O1)NC2=CC=CC=C2)C3=CC=C(C=C3)OC4=CC=CC=C4 InChI=1S/C22H18N2O4/c1-22(16-12-14-19(15-13-16)27-18-10-6-3-7-11-18)20(25)24(21(26)28-22)23-17-8-4-2-5-9-17/h2-15,23H,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes with Negative RMS: The United Kingdom Famoxadone (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance famoxadone 16Jul2015 2015 doi:10.2903/j.efsa.2015.4194
+Famoxadone 603-520-1 131807-57-3 single chemical entity Component is identical to the substance Famoxadone 603-520-1 131807-57-3 3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione Famoxadone C22H18N2O4 CC1(C(=O)N(C(=O)O1)NC2=CC=CC=C2)C3=CC=C(C=C3)OC4=CC=CC=C4 InChI=1S/C22H18N2O4/c1-22(16-12-14-19(15-13-16)27-18-10-6-3-7-11-18)20(25)24(21(26)28-22)23-17-8-4-2-5-9-17/h2-15,23H,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes without Positive RMS: The United Kingdom Famoxadone (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance famoxadone 16Jul2015 2015 doi:10.2903/j.efsa.2015.4194
+Famoxadone 603-520-1 131807-57-3 single chemical entity Component is identical to the substance Famoxadone 603-520-1 131807-57-3 3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione Famoxadone C22H18N2O4 CC1(C(=O)N(C(=O)O1)NC2=CC=CC=C2)C3=CC=C(C=C3)OC4=CC=CC=C4 InChI=1S/C22H18N2O4/c1-22(16-12-14-19(15-13-16)27-18-10-6-3-7-11-18)20(25)24(21(26)28-22)23-17-8-4-2-5-9-17/h2-15,23H,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Famoxadone (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance famoxadone 16Jul2015 2015 doi:10.2903/j.efsa.2015.4194
+Famoxadone 603-520-1 131807-57-3 single chemical entity Component is identical to the substance Famoxadone 603-520-1 131807-57-3 3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione Famoxadone C22H18N2O4 CC1(C(=O)N(C(=O)O1)NC2=CC=CC=C2)C3=CC=C(C=C3)OC4=CC=CC=C4 InChI=1S/C22H18N2O4/c1-22(16-12-14-19(15-13-16)27-18-10-6-3-7-11-18)20(25)24(21(26)28-22)23-17-8-4-2-5-9-17/h2-15,23H,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Positive RMS: The United Kingdom Famoxadone (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance famoxadone 16Jul2015 2015 doi:10.2903/j.efsa.2015.4194
+Famoxadone 603-520-1 131807-57-3 single chemical entity Component is identical to the substance Famoxadone 603-520-1 131807-57-3 3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione Famoxadone C22H18N2O4 CC1(C(=O)N(C(=O)O1)NC2=CC=CC=C2)C3=CC=C(C=C3)OC4=CC=CC=C4 InChI=1S/C22H18N2O4/c1-22(16-12-14-19(15-13-16)27-18-10-6-3-7-11-18)20(25)24(21(26)28-22)23-17-8-4-2-5-9-17/h2-15,23H,1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes without Inconclusive RMS: The United Kingdom Famoxadone (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance famoxadone 16Jul2015 2015 doi:10.2903/j.efsa.2015.4194
+Famoxadone 603-520-1 131807-57-3 single chemical entity Component is identical to the substance Famoxadone 603-520-1 131807-57-3 3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione Famoxadone C22H18N2O4 CC1(C(=O)N(C(=O)O1)NC2=CC=CC=C2)C3=CC=C(C=C3)OC4=CC=CC=C4 InChI=1S/C22H18N2O4/c1-22(16-12-14-19(15-13-16)27-18-10-6-3-7-11-18)20(25)24(21(26)28-22)23-17-8-4-2-5-9-17/h2-15,23H,1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Famoxadone (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance famoxadone 16Jul2015 2015 doi:10.2903/j.efsa.2015.4194
+Famoxadone 603-520-1 131807-57-3 single chemical entity Component is identical to the substance Famoxadone 603-520-1 131807-57-3 3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione Famoxadone C22H18N2O4 CC1(C(=O)N(C(=O)O1)NC2=CC=CC=C2)C3=CC=C(C=C3)OC4=CC=CC=C4 InChI=1S/C22H18N2O4/c1-22(16-12-14-19(15-13-16)27-18-10-6-3-7-11-18)20(25)24(21(26)28-22)23-17-8-4-2-5-9-17/h2-15,23H,1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Famoxadone (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance famoxadone 16Jul2015 2015 doi:10.2903/j.efsa.2015.4194
+Famoxadone 603-520-1 131807-57-3 single chemical entity Component is identical to the substance Famoxadone 603-520-1 131807-57-3 3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione Famoxadone C22H18N2O4 CC1(C(=O)N(C(=O)O1)NC2=CC=CC=C2)C3=CC=C(C=C3)OC4=CC=CC=C4 InChI=1S/C22H18N2O4/c1-22(16-12-14-19(15-13-16)27-18-10-6-3-7-11-18)20(25)24(21(26)28-22)23-17-8-4-2-5-9-17/h2-15,23H,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 No data oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The United Kingdom Famoxadone (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance famoxadone 16Jul2015 2015 doi:10.2903/j.efsa.2015.4194
+Famoxadone 603-520-1 131807-57-3 single chemical entity Component is identical to the substance Famoxadone 603-520-1 131807-57-3 3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione Famoxadone C22H18N2O4 CC1(C(=O)N(C(=O)O1)NC2=CC=CC=C2)C3=CC=C(C=C3)OC4=CC=CC=C4 InChI=1S/C22H18N2O4/c1-22(16-12-14-19(15-13-16)27-18-10-6-3-7-11-18)20(25)24(21(26)28-22)23-17-8-4-2-5-9-17/h2-15,23H,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 No data oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The United Kingdom Famoxadone (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance famoxadone 16Jul2015 2015 doi:10.2903/j.efsa.2015.4194
+Famoxadone 603-520-1 131807-57-3 single chemical entity Component is identical to the substance Famoxadone 603-520-1 131807-57-3 3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione Famoxadone C22H18N2O4 CC1(C(=O)N(C(=O)O1)NC2=CC=CC=C2)C3=CC=C(C=C3)OC4=CC=CC=C4 InChI=1S/C22H18N2O4/c1-22(16-12-14-19(15-13-16)27-18-10-6-3-7-11-18)20(25)24(21(26)28-22)23-17-8-4-2-5-9-17/h2-15,23H,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 No data oral: gavage 72.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The United Kingdom Famoxadone (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance famoxadone 16Jul2015 2015 doi:10.2903/j.efsa.2015.4194
+Famoxadone 603-520-1 131807-57-3 single chemical entity Component is identical to the substance Famoxadone 603-520-1 131807-57-3 3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione Famoxadone C22H18N2O4 CC1(C(=O)N(C(=O)O1)NC2=CC=CC=C2)C3=CC=C(C=C3)OC4=CC=CC=C4 InChI=1S/C22H18N2O4/c1-22(16-12-14-19(15-13-16)27-18-10-6-3-7-11-18)20(25)24(21(26)28-22)23-17-8-4-2-5-9-17/h2-15,23H,1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Sprague-Dawley Male oral: gavage 18.0000000000 h yes not applicable Negative RMS: The United Kingdom Famoxadone (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance famoxadone 16Jul2015 2015 doi:10.2903/j.efsa.2015.4194
+Famoxadone 603-520-1 131807-57-3 single chemical entity Component is identical to the substance Famoxadone 603-520-1 131807-57-3 3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione Famoxadone C22H18N2O4 CC1(C(=O)N(C(=O)O1)NC2=CC=CC=C2)C3=CC=C(C=C3)OC4=CC=CC=C4 InChI=1S/C22H18N2O4/c1-22(16-12-14-19(15-13-16)27-18-10-6-3-7-11-18)20(25)24(21(26)28-22)23-17-8-4-2-5-9-17/h2-15,23H,1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Sprague-Dawley Male oral: gavage 4.0000000000 h yes not applicable Negative RMS: The United Kingdom Famoxadone (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance famoxadone 16Jul2015 2015 doi:10.2903/j.efsa.2015.4194
+Famoxadone 603-520-1 131807-57-3 single chemical entity Component is identical to the substance Famoxadone 603-520-1 131807-57-3 3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione Famoxadone C22H18N2O4 CC1(C(=O)N(C(=O)O1)NC2=CC=CC=C2)C3=CC=C(C=C3)OC4=CC=CC=C4 InChI=1S/C22H18N2O4/c1-22(16-12-14-19(15-13-16)27-18-10-6-3-7-11-18)20(25)24(21(26)28-22)23-17-8-4-2-5-9-17/h2-15,23H,1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Sprague-Dawley 5 Male oral: gavage 16.0000000000 h yes not applicable Negative RMS: The United Kingdom Famoxadone (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance famoxadone 16Jul2015 2015 doi:10.2903/j.efsa.2015.4194
+Famoxadone 603-520-1 131807-57-3 single chemical entity Component is identical to the substance Famoxadone 603-520-1 131807-57-3 3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione Famoxadone C22H18N2O4 CC1(C(=O)N(C(=O)O1)NC2=CC=CC=C2)C3=CC=C(C=C3)OC4=CC=CC=C4 InChI=1S/C22H18N2O4/c1-22(16-12-14-19(15-13-16)27-18-10-6-3-7-11-18)20(25)24(21(26)28-22)23-17-8-4-2-5-9-17/h2-15,23H,1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Sprague-Dawley 5 Male oral: gavage 4.0000000000 h yes not applicable Negative RMS: The United Kingdom Famoxadone (Renewal Assessment Report) 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance famoxadone 16Jul2015 2015 doi:10.2903/j.efsa.2015.4194
+Quizalofop-P-ethyl 600-119-3 100646-51-3 single chemical entity Component is identical to the substance Quizalofop-P-ethyl 600-119-3 100646-51-3 Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate Quizalofop-P-ethyl C19H17ClN2O4 CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Finland Quizalofop-p-ethyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl). 14Jul2009 2009 doi:10.2903/j.efsa.2009.205r
+Quizalofop-P-ethyl 600-119-3 100646-51-3 single chemical entity Component is identical to the substance Quizalofop-P-ethyl 600-119-3 100646-51-3 Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate Quizalofop-P-ethyl C19H17ClN2O4 CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Finland Quizalofop-p-ethyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl). 14Jul2009 2009 doi:10.2903/j.efsa.2009.205r
+Quizalofop-P-ethyl 600-119-3 100646-51-3 single chemical entity Component is identical to the substance Quizalofop-P-ethyl 600-119-3 100646-51-3 Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate Quizalofop-P-ethyl C19H17ClN2O4 CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Finland Quizalofop-p-ethyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl). 14Jul2009 2009 doi:10.2903/j.efsa.2009.205r
+Quizalofop-P-ethyl 600-119-3 100646-51-3 single chemical entity Component is identical to the substance Quizalofop-P-ethyl 600-119-3 100646-51-3 Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate Quizalofop-P-ethyl C19H17ClN2O4 CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Finland Quizalofop-p-ethyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl). 14Jul2009 2009 doi:10.2903/j.efsa.2009.205r
+Quizalofop-P-ethyl 600-119-3 100646-51-3 single chemical entity Component is identical to the substance Quizalofop-P-ethyl 600-119-3 100646-51-3 Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate Quizalofop-P-ethyl C19H17ClN2O4 CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Finland Quizalofop-p-ethyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl). 14Jul2009 2009 doi:10.2903/j.efsa.2009.205r
+Quizalofop-P-ethyl 600-119-3 100646-51-3 single chemical entity Component is identical to the substance Quizalofop-P-ethyl 600-119-3 100646-51-3 Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate Quizalofop-P-ethyl C19H17ClN2O4 CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Finland Quizalofop-p-ethyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl). 14Jul2009 2009 doi:10.2903/j.efsa.2009.205r
+Quizalofop-P-ethyl 600-119-3 100646-51-3 single chemical entity Component is identical to the substance Quizalofop-P-ethyl 600-119-3 100646-51-3 Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate Quizalofop-P-ethyl C19H17ClN2O4 CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Finland Quizalofop-p-ethyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl). 14Jul2009 2009 doi:10.2903/j.efsa.2009.205r
+Quizalofop-P-ethyl 600-119-3 100646-51-3 single chemical entity Component is identical to the substance Quizalofop-P-ethyl 600-119-3 100646-51-3 Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate Quizalofop-P-ethyl C19H17ClN2O4 CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Finland Quizalofop-p-ethyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl). 14Jul2009 2009 doi:10.2903/j.efsa.2009.205r
+Quizalofop-P-ethyl 600-119-3 100646-51-3 single chemical entity Component is identical to the substance Quizalofop-P-ethyl 600-119-3 100646-51-3 Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate Quizalofop-P-ethyl C19H17ClN2O4 CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Finland Quizalofop-p-ethyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl). 14Jul2009 2009 doi:10.2903/j.efsa.2009.205r
+Quizalofop-P-ethyl 600-119-3 100646-51-3 single chemical entity Component is identical to the substance Quizalofop-P-ethyl 600-119-3 100646-51-3 Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate Quizalofop-P-ethyl C19H17ClN2O4 CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Finland Quizalofop-p-ethyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl). 14Jul2009 2009 doi:10.2903/j.efsa.2009.205r
+Quizalofop-P-ethyl 600-119-3 100646-51-3 single chemical entity Component is identical to the substance Quizalofop-P-ethyl 600-119-3 100646-51-3 Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate Quizalofop-P-ethyl C19H17ClN2O4 CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Finland Quizalofop-p-ethyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl). 14Jul2009 2009 doi:10.2903/j.efsa.2009.205r
+Quizalofop-P-ethyl 600-119-3 100646-51-3 single chemical entity Component is identical to the substance Quizalofop-P-ethyl 600-119-3 100646-51-3 Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate Quizalofop-P-ethyl C19H17ClN2O4 CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported no data without Negative RMS: Finland Quizalofop-p-ethyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl). 14Jul2009 2009 doi:10.2903/j.efsa.2009.205r
+Quizalofop-P-ethyl 600-119-3 100646-51-3 single chemical entity Component is identical to the substance Quizalofop-P-ethyl 600-119-3 100646-51-3 Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate Quizalofop-P-ethyl C19H17ClN2O4 CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Finland Quizalofop-p-ethyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl). 14Jul2009 2009 doi:10.2903/j.efsa.2009.205r
+Quizalofop-P-ethyl 600-119-3 100646-51-3 single chemical entity Component is identical to the substance Quizalofop-P-ethyl 600-119-3 100646-51-3 Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate Quizalofop-P-ethyl C19H17ClN2O4 CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Finland Quizalofop-p-ethyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl). 14Jul2009 2009 doi:10.2903/j.efsa.2009.205r
+Quizalofop-P-ethyl 600-119-3 100646-51-3 single chemical entity Component is identical to the substance Quizalofop-P-ethyl 600-119-3 100646-51-3 Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate Quizalofop-P-ethyl C19H17ClN2O4 CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported no data without Negative RMS: Finland Quizalofop-p-ethyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl). 14Jul2009 2009 doi:10.2903/j.efsa.2009.205r
+Quizalofop-P-ethyl 600-119-3 100646-51-3 single chemical entity Component is identical to the substance Quizalofop-P-ethyl 600-119-3 100646-51-3 Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate Quizalofop-P-ethyl C19H17ClN2O4 CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported no data with Negative RMS: Finland Quizalofop-p-ethyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl). 14Jul2009 2009 doi:10.2903/j.efsa.2009.205r
+Quizalofop-P-ethyl 600-119-3 100646-51-3 single chemical entity Component is identical to the substance Quizalofop-P-ethyl 600-119-3 100646-51-3 Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate Quizalofop-P-ethyl C19H17ClN2O4 CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle with Negative RMS: Finland Quizalofop-p-ethyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl). 14Jul2009 2009 doi:10.2903/j.efsa.2009.205r
+Quizalofop-P-ethyl 600-119-3 100646-51-3 single chemical entity Component is identical to the substance Quizalofop-P-ethyl 600-119-3 100646-51-3 Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate Quizalofop-P-ethyl C19H17ClN2O4 CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Finland Quizalofop-p-ethyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl). 14Jul2009 2009 doi:10.2903/j.efsa.2009.205r
+Quizalofop-P-ethyl 600-119-3 100646-51-3 single chemical entity Component is identical to the substance Quizalofop-P-ethyl 600-119-3 100646-51-3 Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate Quizalofop-P-ethyl C19H17ClN2O4 CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Finland Quizalofop-p-ethyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl). 14Jul2009 2009 doi:10.2903/j.efsa.2009.205r
+Quizalofop-P-ethyl 600-119-3 100646-51-3 single chemical entity Component is identical to the substance Quizalofop-P-ethyl 600-119-3 100646-51-3 Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate Quizalofop-P-ethyl C19H17ClN2O4 CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Finland Quizalofop-p-ethyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl). 14Jul2009 2009 doi:10.2903/j.efsa.2009.205r
+Quizalofop-P-ethyl 600-119-3 100646-51-3 single chemical entity Component is identical to the substance Quizalofop-P-ethyl 600-119-3 100646-51-3 Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate Quizalofop-P-ethyl C19H17ClN2O4 CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle without Negative RMS: Finland Quizalofop-p-ethyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl). 14Jul2009 2009 doi:10.2903/j.efsa.2009.205r
+Quizalofop-P-ethyl 600-119-3 100646-51-3 single chemical entity Component is identical to the substance Quizalofop-P-ethyl 600-119-3 100646-51-3 Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate Quizalofop-P-ethyl C19H17ClN2O4 CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported no data with Negative RMS: Finland Quizalofop-p-ethyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl). 14Jul2009 2009 doi:10.2903/j.efsa.2009.205r
+Quizalofop-P-ethyl 600-119-3 100646-51-3 single chemical entity Component is identical to the substance Quizalofop-P-ethyl 600-119-3 100646-51-3 Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate Quizalofop-P-ethyl C19H17ClN2O4 CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Finland Quizalofop-p-ethyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl). 14Jul2009 2009 doi:10.2903/j.efsa.2009.205r
+Quizalofop-P-ethyl 600-119-3 100646-51-3 single chemical entity Component is identical to the substance Quizalofop-P-ethyl 600-119-3 100646-51-3 Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate Quizalofop-P-ethyl C19H17ClN2O4 CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Finland Quizalofop-p-ethyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl). 14Jul2009 2009 doi:10.2903/j.efsa.2009.205r
+Quizalofop-P-ethyl 600-119-3 100646-51-3 single chemical entity Component is identical to the substance Quizalofop-P-ethyl 600-119-3 100646-51-3 Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate Quizalofop-P-ethyl C19H17ClN2O4 CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Finland Quizalofop-p-ethyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl). 14Jul2009 2009 doi:10.2903/j.efsa.2009.205r
+Quizalofop-P-ethyl 600-119-3 100646-51-3 single chemical entity Component is identical to the substance Quizalofop-P-ethyl 600-119-3 100646-51-3 Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate Quizalofop-P-ethyl C19H17ClN2O4 CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Finland Quizalofop-p-ethyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl). 14Jul2009 2009 doi:10.2903/j.efsa.2009.205r
+Quizalofop-P-ethyl 600-119-3 100646-51-3 single chemical entity Component is identical to the substance Quizalofop-P-ethyl 600-119-3 100646-51-3 Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate Quizalofop-P-ethyl C19H17ClN2O4 CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Finland Quizalofop-p-ethyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl). 14Jul2009 2009 doi:10.2903/j.efsa.2009.205r
+Quizalofop-P-ethyl 600-119-3 100646-51-3 single chemical entity Component is identical to the substance Quizalofop-P-ethyl 600-119-3 100646-51-3 Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate Quizalofop-P-ethyl C19H17ClN2O4 CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Finland Quizalofop-p-ethyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl). 14Jul2009 2009 doi:10.2903/j.efsa.2009.205r
+Quizalofop-P-ethyl 600-119-3 100646-51-3 single chemical entity Component is identical to the substance Quizalofop-P-ethyl 600-119-3 100646-51-3 Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate Quizalofop-P-ethyl C19H17ClN2O4 CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Finland Quizalofop-p-ethyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl). 14Jul2009 2009 doi:10.2903/j.efsa.2009.205r
+Quizalofop-P-ethyl 600-119-3 100646-51-3 single chemical entity Component is identical to the substance Quizalofop-P-ethyl 600-119-3 100646-51-3 Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate Quizalofop-P-ethyl C19H17ClN2O4 CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Finland Quizalofop-p-ethyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl). 14Jul2009 2009 doi:10.2903/j.efsa.2009.205r
+Quizalofop-P-ethyl 600-119-3 100646-51-3 single chemical entity Component is identical to the substance Quizalofop-P-ethyl 600-119-3 100646-51-3 Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate Quizalofop-P-ethyl C19H17ClN2O4 CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: Finland Quizalofop-p-ethyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl). 14Jul2009 2009 doi:10.2903/j.efsa.2009.205r
+Quizalofop-P-ethyl 600-119-3 100646-51-3 single chemical entity Component is identical to the substance Quizalofop-P-ethyl 600-119-3 100646-51-3 Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate Quizalofop-P-ethyl C19H17ClN2O4 CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: Finland Quizalofop-p-ethyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl). 14Jul2009 2009 doi:10.2903/j.efsa.2009.205r
+Quizalofop-P-ethyl 600-119-3 100646-51-3 single chemical entity Component is identical to the substance Quizalofop-P-ethyl 600-119-3 100646-51-3 Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate Quizalofop-P-ethyl C19H17ClN2O4 CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Finland Quizalofop-p-ethyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl). 14Jul2009 2009 doi:10.2903/j.efsa.2009.205r
+Quizalofop-P-ethyl 600-119-3 100646-51-3 single chemical entity Component is identical to the substance Quizalofop-P-ethyl 600-119-3 100646-51-3 Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate Quizalofop-P-ethyl C19H17ClN2O4 CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Finland Quizalofop-p-ethyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl). 14Jul2009 2009 doi:10.2903/j.efsa.2009.205r
+Quizalofop-P-ethyl 600-119-3 100646-51-3 single chemical entity Component is identical to the substance Quizalofop-P-ethyl 600-119-3 100646-51-3 Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate Quizalofop-P-ethyl C19H17ClN2O4 CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Finland Quizalofop-p-ethyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl). 14Jul2009 2009 doi:10.2903/j.efsa.2009.205r
+Quizalofop-P-ethyl 600-119-3 100646-51-3 single chemical entity Component is identical to the substance Quizalofop-P-ethyl 600-119-3 100646-51-3 Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate Quizalofop-P-ethyl C19H17ClN2O4 CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Finland Quizalofop-p-ethyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl). 14Jul2009 2009 doi:10.2903/j.efsa.2009.205r
+Quizalofop-P-ethyl 600-119-3 100646-51-3 single chemical entity Component is identical to the substance Quizalofop-P-ethyl 600-119-3 100646-51-3 Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate Quizalofop-P-ethyl C19H17ClN2O4 CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration dominant lethal assay in vivo According to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) No Acceptable House mouse (as animal) CD-1 18 Male oral: gavage 5.0000000000 D yes not applicable Negative RMS: Finland Quizalofop-p-ethyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl). 14Jul2009 2009 doi:10.2903/j.efsa.2009.205r
+Quizalofop-P-tefuryl 601-628-3 119738-06-6 single chemical entity Component is identical to the substance Quizalofop-P-tefuryl 601-628-3 119738-06-6 Oxolan-2-ylmethyl 2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate Not in list C22H21ClN2O5 CC(C(=O)OCC1CCCO1)OC2=CC=C(C=C2)OC3=CN=C4C=C(C=CC4=N3)Cl InChI=1S/C22H21ClN2O5/c1-14(22(26)28-13-18-3-2-10-27-18)29-16-5-7-17(8-6-16)30-21-12-24-20-11-15(23)4-9-19(20)25-21/h4-9,11-12,14,18H,2-3,10,13H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Finland Quizalofop-p-tefuryl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl). 14Jul2009 2009 doi:10.2903/j.efsa.2009.205r
+Quizalofop-P-tefuryl 601-628-3 119738-06-6 single chemical entity Component is identical to the substance Quizalofop-P-tefuryl 601-628-3 119738-06-6 Oxolan-2-ylmethyl 2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate Not in list C22H21ClN2O5 CC(C(=O)OCC1CCCO1)OC2=CC=C(C=C2)OC3=CN=C4C=C(C=CC4=N3)Cl InChI=1S/C22H21ClN2O5/c1-14(22(26)28-13-18-3-2-10-27-18)29-16-5-7-17(8-6-16)30-21-12-24-20-11-15(23)4-9-19(20)25-21/h4-9,11-12,14,18H,2-3,10,13H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Finland Quizalofop-p-tefuryl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl). 14Jul2009 2009 doi:10.2903/j.efsa.2009.205r
+Quizalofop-P-tefuryl 601-628-3 119738-06-6 single chemical entity Component is identical to the substance Quizalofop-P-tefuryl 601-628-3 119738-06-6 Oxolan-2-ylmethyl 2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate Not in list C22H21ClN2O5 CC(C(=O)OCC1CCCO1)OC2=CC=C(C=C2)OC3=CN=C4C=C(C=CC4=N3)Cl InChI=1S/C22H21ClN2O5/c1-14(22(26)28-13-18-3-2-10-27-18)29-16-5-7-17(8-6-16)30-21-12-24-20-11-15(23)4-9-19(20)25-21/h4-9,11-12,14,18H,2-3,10,13H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Finland Quizalofop-p-tefuryl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl). 14Jul2009 2009 doi:10.2903/j.efsa.2009.205r
+Quizalofop-P-tefuryl 601-628-3 119738-06-6 single chemical entity Component is identical to the substance Quizalofop-P-tefuryl 601-628-3 119738-06-6 Oxolan-2-ylmethyl 2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate Not in list C22H21ClN2O5 CC(C(=O)OCC1CCCO1)OC2=CC=C(C=C2)OC3=CN=C4C=C(C=CC4=N3)Cl InChI=1S/C22H21ClN2O5/c1-14(22(26)28-13-18-3-2-10-27-18)29-16-5-7-17(8-6-16)30-21-12-24-20-11-15(23)4-9-19(20)25-21/h4-9,11-12,14,18H,2-3,10,13H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Finland Quizalofop-p-tefuryl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl). 14Jul2009 2009 doi:10.2903/j.efsa.2009.205r
+Quizalofop-P-tefuryl 601-628-3 119738-06-6 single chemical entity Component is identical to the substance Quizalofop-P-tefuryl 601-628-3 119738-06-6 Oxolan-2-ylmethyl 2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate Not in list C22H21ClN2O5 CC(C(=O)OCC1CCCO1)OC2=CC=C(C=C2)OC3=CN=C4C=C(C=CC4=N3)Cl InChI=1S/C22H21ClN2O5/c1-14(22(26)28-13-18-3-2-10-27-18)29-16-5-7-17(8-6-16)30-21-12-24-20-11-15(23)4-9-19(20)25-21/h4-9,11-12,14,18H,2-3,10,13H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Finland Quizalofop-p-tefuryl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl). 14Jul2009 2009 doi:10.2903/j.efsa.2009.205r
+Quizalofop-P-tefuryl 601-628-3 119738-06-6 single chemical entity Component is identical to the substance Quizalofop-P-tefuryl 601-628-3 119738-06-6 Oxolan-2-ylmethyl 2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate Not in list C22H21ClN2O5 CC(C(=O)OCC1CCCO1)OC2=CC=C(C=C2)OC3=CN=C4C=C(C=CC4=N3)Cl InChI=1S/C22H21ClN2O5/c1-14(22(26)28-13-18-3-2-10-27-18)29-16-5-7-17(8-6-16)30-21-12-24-20-11-15(23)4-9-19(20)25-21/h4-9,11-12,14,18H,2-3,10,13H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Finland Quizalofop-p-tefuryl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl). 14Jul2009 2009 doi:10.2903/j.efsa.2009.205r
+Quizalofop-P-tefuryl 601-628-3 119738-06-6 single chemical entity Component is identical to the substance Quizalofop-P-tefuryl 601-628-3 119738-06-6 Oxolan-2-ylmethyl 2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate Not in list C22H21ClN2O5 CC(C(=O)OCC1CCCO1)OC2=CC=C(C=C2)OC3=CN=C4C=C(C=CC4=N3)Cl InChI=1S/C22H21ClN2O5/c1-14(22(26)28-13-18-3-2-10-27-18)29-16-5-7-17(8-6-16)30-21-12-24-20-11-15(23)4-9-19(20)25-21/h4-9,11-12,14,18H,2-3,10,13H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Finland Quizalofop-p-tefuryl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl). 14Jul2009 2009 doi:10.2903/j.efsa.2009.205r
+Quizalofop-P-tefuryl 601-628-3 119738-06-6 single chemical entity Component is identical to the substance Quizalofop-P-tefuryl 601-628-3 119738-06-6 Oxolan-2-ylmethyl 2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate Not in list C22H21ClN2O5 CC(C(=O)OCC1CCCO1)OC2=CC=C(C=C2)OC3=CN=C4C=C(C=CC4=N3)Cl InChI=1S/C22H21ClN2O5/c1-14(22(26)28-13-18-3-2-10-27-18)29-16-5-7-17(8-6-16)30-21-12-24-20-11-15(23)4-9-19(20)25-21/h4-9,11-12,14,18H,2-3,10,13H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Finland Quizalofop-p-tefuryl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl). 14Jul2009 2009 doi:10.2903/j.efsa.2009.205r
+Quizalofop-P-tefuryl 601-628-3 119738-06-6 single chemical entity Component is identical to the substance Quizalofop-P-tefuryl 601-628-3 119738-06-6 Oxolan-2-ylmethyl 2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate Not in list C22H21ClN2O5 CC(C(=O)OCC1CCCO1)OC2=CC=C(C=C2)OC3=CN=C4C=C(C=CC4=N3)Cl InChI=1S/C22H21ClN2O5/c1-14(22(26)28-13-18-3-2-10-27-18)29-16-5-7-17(8-6-16)30-21-12-24-20-11-15(23)4-9-19(20)25-21/h4-9,11-12,14,18H,2-3,10,13H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Finland Quizalofop-p-tefuryl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl). 14Jul2009 2009 doi:10.2903/j.efsa.2009.205r
+Quizalofop-P-tefuryl 601-628-3 119738-06-6 single chemical entity Component is identical to the substance Quizalofop-P-tefuryl 601-628-3 119738-06-6 Oxolan-2-ylmethyl 2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate Not in list C22H21ClN2O5 CC(C(=O)OCC1CCCO1)OC2=CC=C(C=C2)OC3=CN=C4C=C(C=CC4=N3)Cl InChI=1S/C22H21ClN2O5/c1-14(22(26)28-13-18-3-2-10-27-18)29-16-5-7-17(8-6-16)30-21-12-24-20-11-15(23)4-9-19(20)25-21/h4-9,11-12,14,18H,2-3,10,13H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Finland Quizalofop-p-tefuryl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl). 14Jul2009 2009 doi:10.2903/j.efsa.2009.205r
+Quizalofop-P-tefuryl 601-628-3 119738-06-6 single chemical entity Component is identical to the substance Quizalofop-P-tefuryl 601-628-3 119738-06-6 Oxolan-2-ylmethyl 2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate Not in list C22H21ClN2O5 CC(C(=O)OCC1CCCO1)OC2=CC=C(C=C2)OC3=CN=C4C=C(C=CC4=N3)Cl InChI=1S/C22H21ClN2O5/c1-14(22(26)28-13-18-3-2-10-27-18)29-16-5-7-17(8-6-16)30-21-12-24-20-11-15(23)4-9-19(20)25-21/h4-9,11-12,14,18H,2-3,10,13H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Finland Quizalofop-p-tefuryl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl). 14Jul2009 2009 doi:10.2903/j.efsa.2009.205r
+Quizalofop-P-tefuryl 601-628-3 119738-06-6 single chemical entity Component is identical to the substance Quizalofop-P-tefuryl 601-628-3 119738-06-6 Oxolan-2-ylmethyl 2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate Not in list C22H21ClN2O5 CC(C(=O)OCC1CCCO1)OC2=CC=C(C=C2)OC3=CN=C4C=C(C=CC4=N3)Cl InChI=1S/C22H21ClN2O5/c1-14(22(26)28-13-18-3-2-10-27-18)29-16-5-7-17(8-6-16)30-21-12-24-20-11-15(23)4-9-19(20)25-21/h4-9,11-12,14,18H,2-3,10,13H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Finland Quizalofop-p-tefuryl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl). 14Jul2009 2009 doi:10.2903/j.efsa.2009.205r
+Quizalofop-P-tefuryl 601-628-3 119738-06-6 single chemical entity Component is identical to the substance Quizalofop-P-tefuryl 601-628-3 119738-06-6 Oxolan-2-ylmethyl 2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate Not in list C22H21ClN2O5 CC(C(=O)OCC1CCCO1)OC2=CC=C(C=C2)OC3=CN=C4C=C(C=CC4=N3)Cl InChI=1S/C22H21ClN2O5/c1-14(22(26)28-13-18-3-2-10-27-18)29-16-5-7-17(8-6-16)30-21-12-24-20-11-15(23)4-9-19(20)25-21/h4-9,11-12,14,18H,2-3,10,13H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative large colonies RMS: Finland Quizalofop-p-tefuryl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl). 14Jul2009 2009 doi:10.2903/j.efsa.2009.205r
+Quizalofop-P-tefuryl 601-628-3 119738-06-6 single chemical entity Component is identical to the substance Quizalofop-P-tefuryl 601-628-3 119738-06-6 Oxolan-2-ylmethyl 2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate Not in list C22H21ClN2O5 CC(C(=O)OCC1CCCO1)OC2=CC=C(C=C2)OC3=CN=C4C=C(C=CC4=N3)Cl InChI=1S/C22H21ClN2O5/c1-14(22(26)28-13-18-3-2-10-27-18)29-16-5-7-17(8-6-16)30-21-12-24-20-11-15(23)4-9-19(20)25-21/h4-9,11-12,14,18H,2-3,10,13H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Inconclusive large colonies RMS: Finland Quizalofop-p-tefuryl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl). 14Jul2009 2009 doi:10.2903/j.efsa.2009.205r
+Quizalofop-P-tefuryl 601-628-3 119738-06-6 single chemical entity Component is identical to the substance Quizalofop-P-tefuryl 601-628-3 119738-06-6 Oxolan-2-ylmethyl 2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate Not in list C22H21ClN2O5 CC(C(=O)OCC1CCCO1)OC2=CC=C(C=C2)OC3=CN=C4C=C(C=CC4=N3)Cl InChI=1S/C22H21ClN2O5/c1-14(22(26)28-13-18-3-2-10-27-18)29-16-5-7-17(8-6-16)30-21-12-24-20-11-15(23)4-9-19(20)25-21/h4-9,11-12,14,18H,2-3,10,13H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative small colonies RMS: Finland Quizalofop-p-tefuryl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl). 14Jul2009 2009 doi:10.2903/j.efsa.2009.205r
+Quizalofop-P-tefuryl 601-628-3 119738-06-6 single chemical entity Component is identical to the substance Quizalofop-P-tefuryl 601-628-3 119738-06-6 Oxolan-2-ylmethyl 2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate Not in list C22H21ClN2O5 CC(C(=O)OCC1CCCO1)OC2=CC=C(C=C2)OC3=CN=C4C=C(C=CC4=N3)Cl InChI=1S/C22H21ClN2O5/c1-14(22(26)28-13-18-3-2-10-27-18)29-16-5-7-17(8-6-16)30-21-12-24-20-11-15(23)4-9-19(20)25-21/h4-9,11-12,14,18H,2-3,10,13H2,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Inconclusive small colonies RMS: Finland Quizalofop-p-tefuryl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl). 14Jul2009 2009 doi:10.2903/j.efsa.2009.205r
+Quizalofop-P-tefuryl 601-628-3 119738-06-6 single chemical entity Component is identical to the substance Quizalofop-P-tefuryl 601-628-3 119738-06-6 Oxolan-2-ylmethyl 2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate Not in list C22H21ClN2O5 CC(C(=O)OCC1CCCO1)OC2=CC=C(C=C2)OC3=CN=C4C=C(C=CC4=N3)Cl InChI=1S/C22H21ClN2O5/c1-14(22(26)28-13-18-3-2-10-27-18)29-16-5-7-17(8-6-16)30-21-12-24-20-11-15(23)4-9-19(20)25-21/h4-9,11-12,14,18H,2-3,10,13H2,1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Finland Quizalofop-p-tefuryl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl). 14Jul2009 2009 doi:10.2903/j.efsa.2009.205r
+Quizalofop-P-tefuryl 601-628-3 119738-06-6 single chemical entity Component is identical to the substance Quizalofop-P-tefuryl 601-628-3 119738-06-6 Oxolan-2-ylmethyl 2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate Not in list C22H21ClN2O5 CC(C(=O)OCC1CCCO1)OC2=CC=C(C=C2)OC3=CN=C4C=C(C=CC4=N3)Cl InChI=1S/C22H21ClN2O5/c1-14(22(26)28-13-18-3-2-10-27-18)29-16-5-7-17(8-6-16)30-21-12-24-20-11-15(23)4-9-19(20)25-21/h4-9,11-12,14,18H,2-3,10,13H2,1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Sprague-Dawley 10 Male oral: gavage 4.0000000000 h yes not applicable Negative RMS: Finland Quizalofop-p-tefuryl (Final addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl). 14Jul2009 2009 doi:10.2903/j.efsa.2009.205r
+Quizalofop-P-tefuryl 601-628-3 119738-06-6 single chemical entity Component is identical to the substance Quizalofop-P-tefuryl 601-628-3 119738-06-6 Oxolan-2-ylmethyl 2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate Not in list C22H21ClN2O5 CC(C(=O)OCC1CCCO1)OC2=CC=C(C=C2)OC3=CN=C4C=C(C=CC4=N3)Cl InChI=1S/C22H21ClN2O5/c1-14(22(26)28-13-18-3-2-10-27-18)29-16-5-7-17(8-6-16)30-21-12-24-20-11-15(23)4-9-19(20)25-21/h4-9,11-12,14,18H,2-3,10,13H2,1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Sprague-Dawley 10 Male oral: gavage 16.0000000000 h yes not applicable Negative RMS: Finland Quizalofop-p-tefuryl (Final addendum) 2008 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl). 14Jul2009 2009 doi:10.2903/j.efsa.2009.205r
+Quizalofop-P-tefuryl 601-628-3 119738-06-6 single chemical entity Component is identical to the substance Quizalofop-P-tefuryl 601-628-3 119738-06-6 Oxolan-2-ylmethyl 2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate Not in list C22H21ClN2O5 CC(C(=O)OCC1CCCO1)OC2=CC=C(C=C2)OC3=CN=C4C=C(C=CC4=N3)Cl InChI=1S/C22H21ClN2O5/c1-14(22(26)28-13-18-3-2-10-27-18)29-16-5-7-17(8-6-16)30-21-12-24-20-11-15(23)4-9-19(20)25-21/h4-9,11-12,14,18H,2-3,10,13H2,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) ICR 10 Male/Female intraperitoneal 48.0000000000 h yes not applicable Negative direct evidence-cytotoxicity RMS: Finland Quizalofop-p-tefuryl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl). 14Jul2009 2009 doi:10.2903/j.efsa.2009.205r
+Quizalofop-P-tefuryl 601-628-3 119738-06-6 single chemical entity Component is identical to the substance Quizalofop-P-tefuryl 601-628-3 119738-06-6 Oxolan-2-ylmethyl 2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate Not in list C22H21ClN2O5 CC(C(=O)OCC1CCCO1)OC2=CC=C(C=C2)OC3=CN=C4C=C(C=CC4=N3)Cl InChI=1S/C22H21ClN2O5/c1-14(22(26)28-13-18-3-2-10-27-18)29-16-5-7-17(8-6-16)30-21-12-24-20-11-15(23)4-9-19(20)25-21/h4-9,11-12,14,18H,2-3,10,13H2,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) ICR 10 Male/Female intraperitoneal 24.0000000000 h yes not applicable Negative direct evidence-cytotoxicity RMS: Finland Quizalofop-p-tefuryl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl). 14Jul2009 2009 doi:10.2903/j.efsa.2009.205r
+Foramsulfuron 605-666-1 173159-57-4 single chemical entity Component is identical to the substance Foramsulfuron 605-666-1 605-666-1 173159-57-4 1-(4,6-Dimethoxypyrimidin-2-yl)-3-(2-dimethylaminocarbonyl-5-formamidophenylsulfonyl)urea Foramsulfuron C17H20N6O7S CN(C)C(=O)C1=C(C=C(C=C1)NC=O)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C17H20N6O7S/c1-23(2)15(25)11-6-5-10(18-9-24)7-12(11)31(27,28)22-17(26)21-16-19-13(29-3)8-14(20-16)30-4/h5-9H,1-4H3,(H,18,24)(H2,19,20,21,22,26) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Germany Foramsulfuron (revised Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance foramsulfuron 10Mar2016 2016 doi:10.2903/j.efsa.2016.4421
+Foramsulfuron 605-666-1 173159-57-4 single chemical entity Component is identical to the substance Foramsulfuron 605-666-1 605-666-1 173159-57-4 1-(4,6-Dimethoxypyrimidin-2-yl)-3-(2-dimethylaminocarbonyl-5-formamidophenylsulfonyl)urea Foramsulfuron C17H20N6O7S CN(C)C(=O)C1=C(C=C(C=C1)NC=O)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C17H20N6O7S/c1-23(2)15(25)11-6-5-10(18-9-24)7-12(11)31(27,28)22-17(26)21-16-19-13(29-3)8-14(20-16)30-4/h5-9H,1-4H3,(H,18,24)(H2,19,20,21,22,26) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Germany Foramsulfuron (revised Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance foramsulfuron 10Mar2016 2016 doi:10.2903/j.efsa.2016.4421
+Foramsulfuron 605-666-1 173159-57-4 single chemical entity Component is identical to the substance Foramsulfuron 605-666-1 605-666-1 173159-57-4 1-(4,6-Dimethoxypyrimidin-2-yl)-3-(2-dimethylaminocarbonyl-5-formamidophenylsulfonyl)urea Foramsulfuron C17H20N6O7S CN(C)C(=O)C1=C(C=C(C=C1)NC=O)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C17H20N6O7S/c1-23(2)15(25)11-6-5-10(18-9-24)7-12(11)31(27,28)22-17(26)21-16-19-13(29-3)8-14(20-16)30-4/h5-9H,1-4H3,(H,18,24)(H2,19,20,21,22,26) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany Foramsulfuron (revised Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance foramsulfuron 10Mar2016 2016 doi:10.2903/j.efsa.2016.4421
+Foramsulfuron 605-666-1 173159-57-4 single chemical entity Component is identical to the substance Foramsulfuron 605-666-1 605-666-1 173159-57-4 1-(4,6-Dimethoxypyrimidin-2-yl)-3-(2-dimethylaminocarbonyl-5-formamidophenylsulfonyl)urea Foramsulfuron C17H20N6O7S CN(C)C(=O)C1=C(C=C(C=C1)NC=O)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C17H20N6O7S/c1-23(2)15(25)11-6-5-10(18-9-24)7-12(11)31(27,28)22-17(26)21-16-19-13(29-3)8-14(20-16)30-4/h5-9H,1-4H3,(H,18,24)(H2,19,20,21,22,26) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany Foramsulfuron (revised Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance foramsulfuron 10Mar2016 2016 doi:10.2903/j.efsa.2016.4421
+Foramsulfuron 605-666-1 173159-57-4 single chemical entity Component is identical to the substance Foramsulfuron 605-666-1 605-666-1 173159-57-4 1-(4,6-Dimethoxypyrimidin-2-yl)-3-(2-dimethylaminocarbonyl-5-formamidophenylsulfonyl)urea Foramsulfuron C17H20N6O7S CN(C)C(=O)C1=C(C=C(C=C1)NC=O)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C17H20N6O7S/c1-23(2)15(25)11-6-5-10(18-9-24)7-12(11)31(27,28)22-17(26)21-16-19-13(29-3)8-14(20-16)30-4/h5-9H,1-4H3,(H,18,24)(H2,19,20,21,22,26) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany Foramsulfuron (revised Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance foramsulfuron 10Mar2016 2016 doi:10.2903/j.efsa.2016.4421
+Foramsulfuron 605-666-1 173159-57-4 single chemical entity Component is identical to the substance Foramsulfuron 605-666-1 605-666-1 173159-57-4 1-(4,6-Dimethoxypyrimidin-2-yl)-3-(2-dimethylaminocarbonyl-5-formamidophenylsulfonyl)urea Foramsulfuron C17H20N6O7S CN(C)C(=O)C1=C(C=C(C=C1)NC=O)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C17H20N6O7S/c1-23(2)15(25)11-6-5-10(18-9-24)7-12(11)31(27,28)22-17(26)21-16-19-13(29-3)8-14(20-16)30-4/h5-9H,1-4H3,(H,18,24)(H2,19,20,21,22,26) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany Foramsulfuron (revised Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance foramsulfuron 10Mar2016 2016 doi:10.2903/j.efsa.2016.4421
+Foramsulfuron 605-666-1 173159-57-4 single chemical entity Component is identical to the substance Foramsulfuron 605-666-1 605-666-1 173159-57-4 1-(4,6-Dimethoxypyrimidin-2-yl)-3-(2-dimethylaminocarbonyl-5-formamidophenylsulfonyl)urea Foramsulfuron C17H20N6O7S CN(C)C(=O)C1=C(C=C(C=C1)NC=O)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C17H20N6O7S/c1-23(2)15(25)11-6-5-10(18-9-24)7-12(11)31(27,28)22-17(26)21-16-19-13(29-3)8-14(20-16)30-4/h5-9H,1-4H3,(H,18,24)(H2,19,20,21,22,26) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany Foramsulfuron (revised Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance foramsulfuron 10Mar2016 2016 doi:10.2903/j.efsa.2016.4421
+Foramsulfuron 605-666-1 173159-57-4 single chemical entity Component is identical to the substance Foramsulfuron 605-666-1 605-666-1 173159-57-4 1-(4,6-Dimethoxypyrimidin-2-yl)-3-(2-dimethylaminocarbonyl-5-formamidophenylsulfonyl)urea Foramsulfuron C17H20N6O7S CN(C)C(=O)C1=C(C=C(C=C1)NC=O)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C17H20N6O7S/c1-23(2)15(25)11-6-5-10(18-9-24)7-12(11)31(27,28)22-17(26)21-16-19-13(29-3)8-14(20-16)30-4/h5-9H,1-4H3,(H,18,24)(H2,19,20,21,22,26) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany Foramsulfuron (revised Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance foramsulfuron 10Mar2016 2016 doi:10.2903/j.efsa.2016.4421
+Foramsulfuron 605-666-1 173159-57-4 single chemical entity Component is identical to the substance Foramsulfuron 605-666-1 605-666-1 173159-57-4 1-(4,6-Dimethoxypyrimidin-2-yl)-3-(2-dimethylaminocarbonyl-5-formamidophenylsulfonyl)urea Foramsulfuron C17H20N6O7S CN(C)C(=O)C1=C(C=C(C=C1)NC=O)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C17H20N6O7S/c1-23(2)15(25)11-6-5-10(18-9-24)7-12(11)31(27,28)22-17(26)21-16-19-13(29-3)8-14(20-16)30-4/h5-9H,1-4H3,(H,18,24)(H2,19,20,21,22,26) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany Foramsulfuron (revised Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance foramsulfuron 10Mar2016 2016 doi:10.2903/j.efsa.2016.4421
+Foramsulfuron 605-666-1 173159-57-4 single chemical entity Component is identical to the substance Foramsulfuron 605-666-1 605-666-1 173159-57-4 1-(4,6-Dimethoxypyrimidin-2-yl)-3-(2-dimethylaminocarbonyl-5-formamidophenylsulfonyl)urea Foramsulfuron C17H20N6O7S CN(C)C(=O)C1=C(C=C(C=C1)NC=O)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C17H20N6O7S/c1-23(2)15(25)11-6-5-10(18-9-24)7-12(11)31(27,28)22-17(26)21-16-19-13(29-3)8-14(20-16)30-4/h5-9H,1-4H3,(H,18,24)(H2,19,20,21,22,26) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany Foramsulfuron (revised Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance foramsulfuron 10Mar2016 2016 doi:10.2903/j.efsa.2016.4421
+Foramsulfuron 605-666-1 173159-57-4 single chemical entity Component is identical to the substance Foramsulfuron 605-666-1 605-666-1 173159-57-4 1-(4,6-Dimethoxypyrimidin-2-yl)-3-(2-dimethylaminocarbonyl-5-formamidophenylsulfonyl)urea Foramsulfuron C17H20N6O7S CN(C)C(=O)C1=C(C=C(C=C1)NC=O)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C17H20N6O7S/c1-23(2)15(25)11-6-5-10(18-9-24)7-12(11)31(27,28)22-17(26)21-16-19-13(29-3)8-14(20-16)30-4/h5-9H,1-4H3,(H,18,24)(H2,19,20,21,22,26) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes without Positive RMS: Germany Foramsulfuron (revised Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance foramsulfuron 10Mar2016 2016 doi:10.2903/j.efsa.2016.4421
+Foramsulfuron 605-666-1 173159-57-4 single chemical entity Component is identical to the substance Foramsulfuron 605-666-1 605-666-1 173159-57-4 1-(4,6-Dimethoxypyrimidin-2-yl)-3-(2-dimethylaminocarbonyl-5-formamidophenylsulfonyl)urea Foramsulfuron C17H20N6O7S CN(C)C(=O)C1=C(C=C(C=C1)NC=O)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C17H20N6O7S/c1-23(2)15(25)11-6-5-10(18-9-24)7-12(11)31(27,28)22-17(26)21-16-19-13(29-3)8-14(20-16)30-4/h5-9H,1-4H3,(H,18,24)(H2,19,20,21,22,26) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes with Negative RMS: Germany Foramsulfuron (revised Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance foramsulfuron 10Mar2016 2016 doi:10.2903/j.efsa.2016.4421
+Foramsulfuron 605-666-1 173159-57-4 single chemical entity Component is identical to the substance Foramsulfuron 605-666-1 605-666-1 173159-57-4 1-(4,6-Dimethoxypyrimidin-2-yl)-3-(2-dimethylaminocarbonyl-5-formamidophenylsulfonyl)urea Foramsulfuron C17H20N6O7S CN(C)C(=O)C1=C(C=C(C=C1)NC=O)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C17H20N6O7S/c1-23(2)15(25)11-6-5-10(18-9-24)7-12(11)31(27,28)22-17(26)21-16-19-13(29-3)8-14(20-16)30-4/h5-9H,1-4H3,(H,18,24)(H2,19,20,21,22,26) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: Germany Foramsulfuron (revised Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance foramsulfuron 10Mar2016 2016 doi:10.2903/j.efsa.2016.4421
+Foramsulfuron 605-666-1 173159-57-4 single chemical entity Component is identical to the substance Foramsulfuron 605-666-1 605-666-1 173159-57-4 1-(4,6-Dimethoxypyrimidin-2-yl)-3-(2-dimethylaminocarbonyl-5-formamidophenylsulfonyl)urea Foramsulfuron C17H20N6O7S CN(C)C(=O)C1=C(C=C(C=C1)NC=O)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C17H20N6O7S/c1-23(2)15(25)11-6-5-10(18-9-24)7-12(11)31(27,28)22-17(26)21-16-19-13(29-3)8-14(20-16)30-4/h5-9H,1-4H3,(H,18,24)(H2,19,20,21,22,26) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: Germany Foramsulfuron (revised Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance foramsulfuron 10Mar2016 2016 doi:10.2903/j.efsa.2016.4421
+Foramsulfuron 605-666-1 173159-57-4 single chemical entity Component is identical to the substance Foramsulfuron 605-666-1 605-666-1 173159-57-4 1-(4,6-Dimethoxypyrimidin-2-yl)-3-(2-dimethylaminocarbonyl-5-formamidophenylsulfonyl)urea Foramsulfuron C17H20N6O7S CN(C)C(=O)C1=C(C=C(C=C1)NC=O)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C17H20N6O7S/c1-23(2)15(25)11-6-5-10(18-9-24)7-12(11)31(27,28)22-17(26)21-16-19-13(29-3)8-14(20-16)30-4/h5-9H,1-4H3,(H,18,24)(H2,19,20,21,22,26) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 24.0000000000 h yes not applicable Negative no evidence RMS: Germany Foramsulfuron (revised Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance foramsulfuron 10Mar2016 2016 doi:10.2903/j.efsa.2016.4421
+Foramsulfuron 605-666-1 173159-57-4 single chemical entity Component is identical to the substance Foramsulfuron 605-666-1 605-666-1 173159-57-4 1-(4,6-Dimethoxypyrimidin-2-yl)-3-(2-dimethylaminocarbonyl-5-formamidophenylsulfonyl)urea Foramsulfuron C17H20N6O7S CN(C)C(=O)C1=C(C=C(C=C1)NC=O)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C17H20N6O7S/c1-23(2)15(25)11-6-5-10(18-9-24)7-12(11)31(27,28)22-17(26)21-16-19-13(29-3)8-14(20-16)30-4/h5-9H,1-4H3,(H,18,24)(H2,19,20,21,22,26) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 48.0000000000 h yes not applicable Negative no evidence RMS: Germany Foramsulfuron (revised Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance foramsulfuron 10Mar2016 2016 doi:10.2903/j.efsa.2016.4421
+Foramsulfuron 605-666-1 173159-57-4 single chemical entity Component is identical to the substance Foramsulfuron 605-666-1 605-666-1 173159-57-4 1-(4,6-Dimethoxypyrimidin-2-yl)-3-(2-dimethylaminocarbonyl-5-formamidophenylsulfonyl)urea Foramsulfuron C17H20N6O7S CN(C)C(=O)C1=C(C=C(C=C1)NC=O)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C17H20N6O7S/c1-23(2)15(25)11-6-5-10(18-9-24)7-12(11)31(27,28)22-17(26)21-16-19-13(29-3)8-14(20-16)30-4/h5-9H,1-4H3,(H,18,24)(H2,19,20,21,22,26) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 12.0000000000 h yes not applicable Negative no evidence RMS: Germany Foramsulfuron (revised Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance foramsulfuron 10Mar2016 2016 doi:10.2903/j.efsa.2016.4421
+Foramsulfuron 605-666-1 173159-57-4 single chemical entity Component is identical to the substance Foramsulfuron 605-666-1 605-666-1 173159-57-4 1-(4,6-Dimethoxypyrimidin-2-yl)-3-(2-dimethylaminocarbonyl-5-formamidophenylsulfonyl)urea Foramsulfuron C17H20N6O7S CN(C)C(=O)C1=C(C=C(C=C1)NC=O)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C17H20N6O7S/c1-23(2)15(25)11-6-5-10(18-9-24)7-12(11)31(27,28)22-17(26)21-16-19-13(29-3)8-14(20-16)30-4/h5-9H,1-4H3,(H,18,24)(H2,19,20,21,22,26) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Sprague-Dawley 8 Male oral: gavage 2.0000000000 h yes not applicable Negative RMS: Germany Foramsulfuron (revised Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance foramsulfuron 10Mar2016 2016 doi:10.2903/j.efsa.2016.4421
+Foramsulfuron 605-666-1 173159-57-4 single chemical entity Component is identical to the substance Foramsulfuron 605-666-1 605-666-1 173159-57-4 1-(4,6-Dimethoxypyrimidin-2-yl)-3-(2-dimethylaminocarbonyl-5-formamidophenylsulfonyl)urea Foramsulfuron C17H20N6O7S CN(C)C(=O)C1=C(C=C(C=C1)NC=O)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC InChI=1S/C17H20N6O7S/c1-23(2)15(25)11-6-5-10(18-9-24)7-12(11)31(27,28)22-17(26)21-16-19-13(29-3)8-14(20-16)30-4/h5-9H,1-4H3,(H,18,24)(H2,19,20,21,22,26) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Sprague-Dawley 8 Male oral: gavage 14.0000000000 h yes not applicable Negative RMS: Germany Foramsulfuron (revised Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance foramsulfuron 10Mar2016 2016 doi:10.2903/j.efsa.2016.4421
+Tau-fluvalinate 102851-06-9 single chemical entity Component is identical to the substance Tau-fluvalinate 102851-06-9 [cyano-(3-phenoxyphenyl)methyl](2R)-2-[2-chloro-4-(trifluoromethyl)anilino]-3-methylbutanoate tau-Fluvalinate C26H22ClF3N2O3 CC(C)[C@H](C(=O)OC(C#N)C1=CC(=CC=C1)OC2=CC=CC=C2)NC3=C(C=C(C=C3)C(F)(F)F)Cl InChI=1S/C26H22ClF3N2O3/c1-16(2)24(32-22-12-11-18(14-21(22)27)26(28,29)30)25(33)35-23(15-31)17-7-6-10-20(13-17)34-19-8-4-3-5-9-19/h3-14,16,23-24,32H,1-2H3/t23?,24-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Denmark Tau-fluvalinate 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate 07Jul2010 2010 doi:10.2903/j.efsa.2010.1645
+Tau-fluvalinate 102851-06-9 single chemical entity Component is identical to the substance Tau-fluvalinate 102851-06-9 [cyano-(3-phenoxyphenyl)methyl](2R)-2-[2-chloro-4-(trifluoromethyl)anilino]-3-methylbutanoate tau-Fluvalinate C26H22ClF3N2O3 CC(C)[C@H](C(=O)OC(C#N)C1=CC(=CC=C1)OC2=CC=CC=C2)NC3=C(C=C(C=C3)C(F)(F)F)Cl InChI=1S/C26H22ClF3N2O3/c1-16(2)24(32-22-12-11-18(14-21(22)27)26(28,29)30)25(33)35-23(15-31)17-7-6-10-20(13-17)34-19-8-4-3-5-9-19/h3-14,16,23-24,32H,1-2H3/t23?,24-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Denmark Tau-fluvalinate 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate 07Jul2010 2010 doi:10.2903/j.efsa.2010.1645
+Tau-fluvalinate 102851-06-9 single chemical entity Component is identical to the substance Tau-fluvalinate 102851-06-9 [cyano-(3-phenoxyphenyl)methyl](2R)-2-[2-chloro-4-(trifluoromethyl)anilino]-3-methylbutanoate tau-Fluvalinate C26H22ClF3N2O3 CC(C)[C@H](C(=O)OC(C#N)C1=CC(=CC=C1)OC2=CC=CC=C2)NC3=C(C=C(C=C3)C(F)(F)F)Cl InChI=1S/C26H22ClF3N2O3/c1-16(2)24(32-22-12-11-18(14-21(22)27)26(28,29)30)25(33)35-23(15-31)17-7-6-10-20(13-17)34-19-8-4-3-5-9-19/h3-14,16,23-24,32H,1-2H3/t23?,24-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Denmark Tau-fluvalinate 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate 07Jul2010 2010 doi:10.2903/j.efsa.2010.1645
+Tau-fluvalinate 102851-06-9 single chemical entity Component is identical to the substance Tau-fluvalinate 102851-06-9 [cyano-(3-phenoxyphenyl)methyl](2R)-2-[2-chloro-4-(trifluoromethyl)anilino]-3-methylbutanoate tau-Fluvalinate C26H22ClF3N2O3 CC(C)[C@H](C(=O)OC(C#N)C1=CC(=CC=C1)OC2=CC=CC=C2)NC3=C(C=C(C=C3)C(F)(F)F)Cl InChI=1S/C26H22ClF3N2O3/c1-16(2)24(32-22-12-11-18(14-21(22)27)26(28,29)30)25(33)35-23(15-31)17-7-6-10-20(13-17)34-19-8-4-3-5-9-19/h3-14,16,23-24,32H,1-2H3/t23?,24-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Denmark Tau-fluvalinate 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate 07Jul2010 2010 doi:10.2903/j.efsa.2010.1645
+Tau-fluvalinate 102851-06-9 single chemical entity Component is identical to the substance Tau-fluvalinate 102851-06-9 [cyano-(3-phenoxyphenyl)methyl](2R)-2-[2-chloro-4-(trifluoromethyl)anilino]-3-methylbutanoate tau-Fluvalinate C26H22ClF3N2O3 CC(C)[C@H](C(=O)OC(C#N)C1=CC(=CC=C1)OC2=CC=CC=C2)NC3=C(C=C(C=C3)C(F)(F)F)Cl InChI=1S/C26H22ClF3N2O3/c1-16(2)24(32-22-12-11-18(14-21(22)27)26(28,29)30)25(33)35-23(15-31)17-7-6-10-20(13-17)34-19-8-4-3-5-9-19/h3-14,16,23-24,32H,1-2H3/t23?,24-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Denmark Tau-fluvalinate 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate 07Jul2010 2010 doi:10.2903/j.efsa.2010.1645
+Tau-fluvalinate 102851-06-9 single chemical entity Component is identical to the substance Tau-fluvalinate 102851-06-9 [cyano-(3-phenoxyphenyl)methyl](2R)-2-[2-chloro-4-(trifluoromethyl)anilino]-3-methylbutanoate tau-Fluvalinate C26H22ClF3N2O3 CC(C)[C@H](C(=O)OC(C#N)C1=CC(=CC=C1)OC2=CC=CC=C2)NC3=C(C=C(C=C3)C(F)(F)F)Cl InChI=1S/C26H22ClF3N2O3/c1-16(2)24(32-22-12-11-18(14-21(22)27)26(28,29)30)25(33)35-23(15-31)17-7-6-10-20(13-17)34-19-8-4-3-5-9-19/h3-14,16,23-24,32H,1-2H3/t23?,24-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Denmark Tau-fluvalinate 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate 07Jul2010 2010 doi:10.2903/j.efsa.2010.1645
+Tau-fluvalinate 102851-06-9 single chemical entity Component is identical to the substance Tau-fluvalinate 102851-06-9 [cyano-(3-phenoxyphenyl)methyl](2R)-2-[2-chloro-4-(trifluoromethyl)anilino]-3-methylbutanoate tau-Fluvalinate C26H22ClF3N2O3 CC(C)[C@H](C(=O)OC(C#N)C1=CC(=CC=C1)OC2=CC=CC=C2)NC3=C(C=C(C=C3)C(F)(F)F)Cl InChI=1S/C26H22ClF3N2O3/c1-16(2)24(32-22-12-11-18(14-21(22)27)26(28,29)30)25(33)35-23(15-31)17-7-6-10-20(13-17)34-19-8-4-3-5-9-19/h3-14,16,23-24,32H,1-2H3/t23?,24-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Denmark Tau-fluvalinate 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate 07Jul2010 2010 doi:10.2903/j.efsa.2010.1645
+Tau-fluvalinate 102851-06-9 single chemical entity Component is identical to the substance Tau-fluvalinate 102851-06-9 [cyano-(3-phenoxyphenyl)methyl](2R)-2-[2-chloro-4-(trifluoromethyl)anilino]-3-methylbutanoate tau-Fluvalinate C26H22ClF3N2O3 CC(C)[C@H](C(=O)OC(C#N)C1=CC(=CC=C1)OC2=CC=CC=C2)NC3=C(C=C(C=C3)C(F)(F)F)Cl InChI=1S/C26H22ClF3N2O3/c1-16(2)24(32-22-12-11-18(14-21(22)27)26(28,29)30)25(33)35-23(15-31)17-7-6-10-20(13-17)34-19-8-4-3-5-9-19/h3-14,16,23-24,32H,1-2H3/t23?,24-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Denmark Tau-fluvalinate 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate 07Jul2010 2010 doi:10.2903/j.efsa.2010.1645
+Tau-fluvalinate 102851-06-9 single chemical entity Component is identical to the substance Tau-fluvalinate 102851-06-9 [cyano-(3-phenoxyphenyl)methyl](2R)-2-[2-chloro-4-(trifluoromethyl)anilino]-3-methylbutanoate tau-Fluvalinate C26H22ClF3N2O3 CC(C)[C@H](C(=O)OC(C#N)C1=CC(=CC=C1)OC2=CC=CC=C2)NC3=C(C=C(C=C3)C(F)(F)F)Cl InChI=1S/C26H22ClF3N2O3/c1-16(2)24(32-22-12-11-18(14-21(22)27)26(28,29)30)25(33)35-23(15-31)17-7-6-10-20(13-17)34-19-8-4-3-5-9-19/h3-14,16,23-24,32H,1-2H3/t23?,24-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Denmark Tau-fluvalinate 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate 07Jul2010 2010 doi:10.2903/j.efsa.2010.1645
+Tau-fluvalinate 102851-06-9 single chemical entity Component is identical to the substance Tau-fluvalinate 102851-06-9 [cyano-(3-phenoxyphenyl)methyl](2R)-2-[2-chloro-4-(trifluoromethyl)anilino]-3-methylbutanoate tau-Fluvalinate C26H22ClF3N2O3 CC(C)[C@H](C(=O)OC(C#N)C1=CC(=CC=C1)OC2=CC=CC=C2)NC3=C(C=C(C=C3)C(F)(F)F)Cl InChI=1S/C26H22ClF3N2O3/c1-16(2)24(32-22-12-11-18(14-21(22)27)26(28,29)30)25(33)35-23(15-31)17-7-6-10-20(13-17)34-19-8-4-3-5-9-19/h3-14,16,23-24,32H,1-2H3/t23?,24-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Denmark Tau-fluvalinate 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate 07Jul2010 2010 doi:10.2903/j.efsa.2010.1645
+Tau-fluvalinate 102851-06-9 single chemical entity Component is identical to the substance Tau-fluvalinate 102851-06-9 [cyano-(3-phenoxyphenyl)methyl](2R)-2-[2-chloro-4-(trifluoromethyl)anilino]-3-methylbutanoate tau-Fluvalinate C26H22ClF3N2O3 CC(C)[C@H](C(=O)OC(C#N)C1=CC(=CC=C1)OC2=CC=CC=C2)NC3=C(C=C(C=C3)C(F)(F)F)Cl InChI=1S/C26H22ClF3N2O3/c1-16(2)24(32-22-12-11-18(14-21(22)27)26(28,29)30)25(33)35-23(15-31)17-7-6-10-20(13-17)34-19-8-4-3-5-9-19/h3-14,16,23-24,32H,1-2H3/t23?,24-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Ambiguous no information RMS: Denmark Tau-fluvalinate 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate 07Jul2010 2010 doi:10.2903/j.efsa.2010.1645
+Tau-fluvalinate 102851-06-9 single chemical entity Component is identical to the substance Tau-fluvalinate 102851-06-9 [cyano-(3-phenoxyphenyl)methyl](2R)-2-[2-chloro-4-(trifluoromethyl)anilino]-3-methylbutanoate tau-Fluvalinate C26H22ClF3N2O3 CC(C)[C@H](C(=O)OC(C#N)C1=CC(=CC=C1)OC2=CC=CC=C2)NC3=C(C=C(C=C3)C(F)(F)F)Cl InChI=1S/C26H22ClF3N2O3/c1-16(2)24(32-22-12-11-18(14-21(22)27)26(28,29)30)25(33)35-23(15-31)17-7-6-10-20(13-17)34-19-8-4-3-5-9-19/h3-14,16,23-24,32H,1-2H3/t23?,24-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative no information RMS: Denmark Tau-fluvalinate 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate 07Jul2010 2010 doi:10.2903/j.efsa.2010.1645
+Tau-fluvalinate 102851-06-9 single chemical entity Component is identical to the substance Tau-fluvalinate 102851-06-9 [cyano-(3-phenoxyphenyl)methyl](2R)-2-[2-chloro-4-(trifluoromethyl)anilino]-3-methylbutanoate tau-Fluvalinate C26H22ClF3N2O3 CC(C)[C@H](C(=O)OC(C#N)C1=CC(=CC=C1)OC2=CC=CC=C2)NC3=C(C=C(C=C3)C(F)(F)F)Cl InChI=1S/C26H22ClF3N2O3/c1-16(2)24(32-22-12-11-18(14-21(22)27)26(28,29)30)25(33)35-23(15-31)17-7-6-10-20(13-17)34-19-8-4-3-5-9-19/h3-14,16,23-24,32H,1-2H3/t23?,24-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro According to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Denmark Tau-fluvalinate 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate 07Jul2010 2010 doi:10.2903/j.efsa.2010.1645
+Tau-fluvalinate 102851-06-9 single chemical entity Component is identical to the substance Tau-fluvalinate 102851-06-9 [cyano-(3-phenoxyphenyl)methyl](2R)-2-[2-chloro-4-(trifluoromethyl)anilino]-3-methylbutanoate tau-Fluvalinate C26H22ClF3N2O3 CC(C)[C@H](C(=O)OC(C#N)C1=CC(=CC=C1)OC2=CC=CC=C2)NC3=C(C=C(C=C3)C(F)(F)F)Cl InChI=1S/C26H22ClF3N2O3/c1-16(2)24(32-22-12-11-18(14-21(22)27)26(28,29)30)25(33)35-23(15-31)17-7-6-10-20(13-17)34-19-8-4-3-5-9-19/h3-14,16,23-24,32H,1-2H3/t23?,24-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro According to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Denmark Tau-fluvalinate 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate 07Jul2010 2010 doi:10.2903/j.efsa.2010.1645
+Tau-fluvalinate 102851-06-9 single chemical entity Component is identical to the substance Tau-fluvalinate 102851-06-9 [cyano-(3-phenoxyphenyl)methyl](2R)-2-[2-chloro-4-(trifluoromethyl)anilino]-3-methylbutanoate tau-Fluvalinate C26H22ClF3N2O3 CC(C)[C@H](C(=O)OC(C#N)C1=CC(=CC=C1)OC2=CC=CC=C2)NC3=C(C=C(C=C3)C(F)(F)F)Cl InChI=1S/C26H22ClF3N2O3/c1-16(2)24(32-22-12-11-18(14-21(22)27)26(28,29)30)25(33)35-23(15-31)17-7-6-10-20(13-17)34-19-8-4-3-5-9-19/h3-14,16,23-24,32H,1-2H3/t23?,24-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Rat (as animal) hepatocytes Not reported yes without Negative RMS: Denmark Tau-fluvalinate 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate 07Jul2010 2010 doi:10.2903/j.efsa.2010.1645
+Tau-fluvalinate 102851-06-9 single chemical entity Component is identical to the substance Tau-fluvalinate 102851-06-9 [cyano-(3-phenoxyphenyl)methyl](2R)-2-[2-chloro-4-(trifluoromethyl)anilino]-3-methylbutanoate tau-Fluvalinate C26H22ClF3N2O3 CC(C)[C@H](C(=O)OC(C#N)C1=CC(=CC=C1)OC2=CC=CC=C2)NC3=C(C=C(C=C3)C(F)(F)F)Cl InChI=1S/C26H22ClF3N2O3/c1-16(2)24(32-22-12-11-18(14-21(22)27)26(28,29)30)25(33)35-23(15-31)17-7-6-10-20(13-17)34-19-8-4-3-5-9-19/h3-14,16,23-24,32H,1-2H3/t23?,24-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Sprague-Dawley 10 Male/Female oral: gavage 48.0000000000 h yes not applicable Negative RMS: Denmark Tau-fluvalinate 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate 07Jul2010 2010 doi:10.2903/j.efsa.2010.1645
+Tau-fluvalinate 102851-06-9 single chemical entity Component is identical to the substance Tau-fluvalinate 102851-06-9 [cyano-(3-phenoxyphenyl)methyl](2R)-2-[2-chloro-4-(trifluoromethyl)anilino]-3-methylbutanoate tau-Fluvalinate C26H22ClF3N2O3 CC(C)[C@H](C(=O)OC(C#N)C1=CC(=CC=C1)OC2=CC=CC=C2)NC3=C(C=C(C=C3)C(F)(F)F)Cl InChI=1S/C26H22ClF3N2O3/c1-16(2)24(32-22-12-11-18(14-21(22)27)26(28,29)30)25(33)35-23(15-31)17-7-6-10-20(13-17)34-19-8-4-3-5-9-19/h3-14,16,23-24,32H,1-2H3/t23?,24-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Sprague-Dawley 10 Male/Female oral: gavage 24.0000000000 h yes not applicable Negative RMS: Denmark Tau-fluvalinate 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate 07Jul2010 2010 doi:10.2903/j.efsa.2010.1645
+Tau-fluvalinate 102851-06-9 single chemical entity Component is identical to the substance Tau-fluvalinate 102851-06-9 [cyano-(3-phenoxyphenyl)methyl](2R)-2-[2-chloro-4-(trifluoromethyl)anilino]-3-methylbutanoate tau-Fluvalinate C26H22ClF3N2O3 CC(C)[C@H](C(=O)OC(C#N)C1=CC(=CC=C1)OC2=CC=CC=C2)NC3=C(C=C(C=C3)C(F)(F)F)Cl InChI=1S/C26H22ClF3N2O3/c1-16(2)24(32-22-12-11-18(14-21(22)27)26(28,29)30)25(33)35-23(15-31)17-7-6-10-20(13-17)34-19-8-4-3-5-9-19/h3-14,16,23-24,32H,1-2H3/t23?,24-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Sprague-Dawley 10 Male/Female oral: gavage 6.0000000000 h yes not applicable Negative RMS: Denmark Tau-fluvalinate 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate 07Jul2010 2010 doi:10.2903/j.efsa.2010.1645
+Tau-fluvalinate 102851-06-9 single chemical entity Component is a metabolite of the substance 2-chloro-4-(trifluoromethyl)aniline 2-chloro-4-(trifluoromethyl)aniline Not in list C7H5ClF3N c1cc(c(cc1C(F)(F)F)Cl)N InChI=1S/C7H5ClF3N/c8-5-3-4(7(9,10)11)1-2-6(5)12/h1-3H,12H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Denmark Tau-fluvalinate 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate 07Jul2010 2010 doi:10.2903/j.efsa.2010.1645
+Tau-fluvalinate 102851-06-9 single chemical entity Component is a metabolite of the substance 2-chloro-4-(trifluoromethyl)aniline 2-chloro-4-(trifluoromethyl)aniline Not in list C7H5ClF3N c1cc(c(cc1C(F)(F)F)Cl)N InChI=1S/C7H5ClF3N/c8-5-3-4(7(9,10)11)1-2-6(5)12/h1-3H,12H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Denmark Tau-fluvalinate 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate 07Jul2010 2010 doi:10.2903/j.efsa.2010.1645
+Tau-fluvalinate 102851-06-9 single chemical entity Component is a metabolite of the substance 2-chloro-4-(trifluoromethyl)aniline 2-chloro-4-(trifluoromethyl)aniline Not in list C7H5ClF3N c1cc(c(cc1C(F)(F)F)Cl)N InChI=1S/C7H5ClF3N/c8-5-3-4(7(9,10)11)1-2-6(5)12/h1-3H,12H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Denmark Tau-fluvalinate 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate 07Jul2010 2010 doi:10.2903/j.efsa.2010.1645
+Tau-fluvalinate 102851-06-9 single chemical entity Component is a metabolite of the substance 2-chloro-4-(trifluoromethyl)aniline 2-chloro-4-(trifluoromethyl)aniline Not in list C7H5ClF3N c1cc(c(cc1C(F)(F)F)Cl)N InChI=1S/C7H5ClF3N/c8-5-3-4(7(9,10)11)1-2-6(5)12/h1-3H,12H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Denmark Tau-fluvalinate 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate 07Jul2010 2010 doi:10.2903/j.efsa.2010.1645
+Tau-fluvalinate 102851-06-9 single chemical entity Component is a metabolite of the substance 2-chloro-4-(trifluoromethyl)aniline 2-chloro-4-(trifluoromethyl)aniline Not in list C7H5ClF3N c1cc(c(cc1C(F)(F)F)Cl)N InChI=1S/C7H5ClF3N/c8-5-3-4(7(9,10)11)1-2-6(5)12/h1-3H,12H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Denmark Tau-fluvalinate 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate 07Jul2010 2010 doi:10.2903/j.efsa.2010.1645
+Tau-fluvalinate 102851-06-9 single chemical entity Component is a metabolite of the substance 2-chloro-4-(trifluoromethyl)aniline 2-chloro-4-(trifluoromethyl)aniline Not in list C7H5ClF3N c1cc(c(cc1C(F)(F)F)Cl)N InChI=1S/C7H5ClF3N/c8-5-3-4(7(9,10)11)1-2-6(5)12/h1-3H,12H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Denmark Tau-fluvalinate 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate 07Jul2010 2010 doi:10.2903/j.efsa.2010.1645
+Tau-fluvalinate 102851-06-9 single chemical entity Component is a metabolite of the substance 2-chloro-4-(trifluoromethyl)aniline 2-chloro-4-(trifluoromethyl)aniline Not in list C7H5ClF3N c1cc(c(cc1C(F)(F)F)Cl)N InChI=1S/C7H5ClF3N/c8-5-3-4(7(9,10)11)1-2-6(5)12/h1-3H,12H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Denmark Tau-fluvalinate 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate 07Jul2010 2010 doi:10.2903/j.efsa.2010.1645
+Tau-fluvalinate 102851-06-9 single chemical entity Component is a metabolite of the substance 2-chloro-4-(trifluoromethyl)aniline 2-chloro-4-(trifluoromethyl)aniline Not in list C7H5ClF3N c1cc(c(cc1C(F)(F)F)Cl)N InChI=1S/C7H5ClF3N/c8-5-3-4(7(9,10)11)1-2-6(5)12/h1-3H,12H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Denmark Tau-fluvalinate 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate 07Jul2010 2010 doi:10.2903/j.efsa.2010.1645
+Tau-fluvalinate 102851-06-9 single chemical entity Component is a metabolite of the substance 2-chloro-4-(trifluoromethyl)aniline 2-chloro-4-(trifluoromethyl)aniline Not in list C7H5ClF3N c1cc(c(cc1C(F)(F)F)Cl)N InChI=1S/C7H5ClF3N/c8-5-3-4(7(9,10)11)1-2-6(5)12/h1-3H,12H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Denmark Tau-fluvalinate 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate 07Jul2010 2010 doi:10.2903/j.efsa.2010.1645
+Tau-fluvalinate 102851-06-9 single chemical entity Component is a metabolite of the substance 2-chloro-4-(trifluoromethyl)aniline 2-chloro-4-(trifluoromethyl)aniline Not in list C7H5ClF3N c1cc(c(cc1C(F)(F)F)Cl)N InChI=1S/C7H5ClF3N/c8-5-3-4(7(9,10)11)1-2-6(5)12/h1-3H,12H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Denmark Tau-fluvalinate 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate 07Jul2010 2010 doi:10.2903/j.efsa.2010.1645
+Tau-fluvalinate 102851-06-9 single chemical entity Component is a metabolite of the substance N-[2-chloro-4-(trifluoromethyl)phenyl]-D-valine N-[2-chloro-4-(trifluoromethyl)phenyl]-D-valine Not in list C12H13ClF3NO2 Clc1cc(ccc1NC(C(O)=O)C(C)C)C(F)(F)F InChI=1/C12H13ClF3NO2/c1-6(2)10(11(18)19)17-9-4-3-7(5-8(9)13)12(14,15)16/h3-6,10,17H,1-2H3,(H,18,19)/t10-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Denmark Tau-fluvalinate 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate 07Jul2010 2010 doi:10.2903/j.efsa.2010.1645
+Tau-fluvalinate 102851-06-9 single chemical entity Component is a metabolite of the substance N-[2-chloro-4-(trifluoromethyl)phenyl]-D-valine N-[2-chloro-4-(trifluoromethyl)phenyl]-D-valine Not in list C12H13ClF3NO2 Clc1cc(ccc1NC(C(O)=O)C(C)C)C(F)(F)F InChI=1/C12H13ClF3NO2/c1-6(2)10(11(18)19)17-9-4-3-7(5-8(9)13)12(14,15)16/h3-6,10,17H,1-2H3,(H,18,19)/t10-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Denmark Tau-fluvalinate 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate 07Jul2010 2010 doi:10.2903/j.efsa.2010.1645
+Tau-fluvalinate 102851-06-9 single chemical entity Component is a metabolite of the substance N-[2-chloro-4-(trifluoromethyl)phenyl]-D-valine N-[2-chloro-4-(trifluoromethyl)phenyl]-D-valine Not in list C12H13ClF3NO2 Clc1cc(ccc1NC(C(O)=O)C(C)C)C(F)(F)F InChI=1/C12H13ClF3NO2/c1-6(2)10(11(18)19)17-9-4-3-7(5-8(9)13)12(14,15)16/h3-6,10,17H,1-2H3,(H,18,19)/t10-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Denmark Tau-fluvalinate 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate 07Jul2010 2010 doi:10.2903/j.efsa.2010.1645
+Tau-fluvalinate 102851-06-9 single chemical entity Component is a metabolite of the substance N-[2-chloro-4-(trifluoromethyl)phenyl]-D-valine N-[2-chloro-4-(trifluoromethyl)phenyl]-D-valine Not in list C12H13ClF3NO2 Clc1cc(ccc1NC(C(O)=O)C(C)C)C(F)(F)F InChI=1/C12H13ClF3NO2/c1-6(2)10(11(18)19)17-9-4-3-7(5-8(9)13)12(14,15)16/h3-6,10,17H,1-2H3,(H,18,19)/t10-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Denmark Tau-fluvalinate 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate 07Jul2010 2010 doi:10.2903/j.efsa.2010.1645
+Tau-fluvalinate 102851-06-9 single chemical entity Component is a metabolite of the substance N-[2-chloro-4-(trifluoromethyl)phenyl]-D-valine N-[2-chloro-4-(trifluoromethyl)phenyl]-D-valine Not in list C12H13ClF3NO2 Clc1cc(ccc1NC(C(O)=O)C(C)C)C(F)(F)F InChI=1/C12H13ClF3NO2/c1-6(2)10(11(18)19)17-9-4-3-7(5-8(9)13)12(14,15)16/h3-6,10,17H,1-2H3,(H,18,19)/t10-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Denmark Tau-fluvalinate 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate 07Jul2010 2010 doi:10.2903/j.efsa.2010.1645
+Tau-fluvalinate 102851-06-9 single chemical entity Component is a metabolite of the substance N-[2-chloro-4-(trifluoromethyl)phenyl]-D-valine N-[2-chloro-4-(trifluoromethyl)phenyl]-D-valine Not in list C12H13ClF3NO2 Clc1cc(ccc1NC(C(O)=O)C(C)C)C(F)(F)F InChI=1/C12H13ClF3NO2/c1-6(2)10(11(18)19)17-9-4-3-7(5-8(9)13)12(14,15)16/h3-6,10,17H,1-2H3,(H,18,19)/t10-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Denmark Tau-fluvalinate 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate 07Jul2010 2010 doi:10.2903/j.efsa.2010.1645
+Tau-fluvalinate 102851-06-9 single chemical entity Component is a metabolite of the substance N-[2-chloro-4-(trifluoromethyl)phenyl]-D-valine N-[2-chloro-4-(trifluoromethyl)phenyl]-D-valine Not in list C12H13ClF3NO2 Clc1cc(ccc1NC(C(O)=O)C(C)C)C(F)(F)F InChI=1/C12H13ClF3NO2/c1-6(2)10(11(18)19)17-9-4-3-7(5-8(9)13)12(14,15)16/h3-6,10,17H,1-2H3,(H,18,19)/t10-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Denmark Tau-fluvalinate 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate 07Jul2010 2010 doi:10.2903/j.efsa.2010.1645
+Tau-fluvalinate 102851-06-9 single chemical entity Component is a metabolite of the substance N-[2-chloro-4-(trifluoromethyl)phenyl]-D-valine N-[2-chloro-4-(trifluoromethyl)phenyl]-D-valine Not in list C12H13ClF3NO2 Clc1cc(ccc1NC(C(O)=O)C(C)C)C(F)(F)F InChI=1/C12H13ClF3NO2/c1-6(2)10(11(18)19)17-9-4-3-7(5-8(9)13)12(14,15)16/h3-6,10,17H,1-2H3,(H,18,19)/t10-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Denmark Tau-fluvalinate 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate 07Jul2010 2010 doi:10.2903/j.efsa.2010.1645
+Tau-fluvalinate 102851-06-9 single chemical entity Component is a metabolite of the substance N-[2-chloro-4-(trifluoromethyl)phenyl]-D-valine N-[2-chloro-4-(trifluoromethyl)phenyl]-D-valine Not in list C12H13ClF3NO2 Clc1cc(ccc1NC(C(O)=O)C(C)C)C(F)(F)F InChI=1/C12H13ClF3NO2/c1-6(2)10(11(18)19)17-9-4-3-7(5-8(9)13)12(14,15)16/h3-6,10,17H,1-2H3,(H,18,19)/t10-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Denmark Tau-fluvalinate 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate 07Jul2010 2010 doi:10.2903/j.efsa.2010.1645
+Tau-fluvalinate 102851-06-9 single chemical entity Component is a metabolite of the substance N-[2-chloro-4-(trifluoromethyl)phenyl]-D-valine N-[2-chloro-4-(trifluoromethyl)phenyl]-D-valine Not in list C12H13ClF3NO2 Clc1cc(ccc1NC(C(O)=O)C(C)C)C(F)(F)F InChI=1/C12H13ClF3NO2/c1-6(2)10(11(18)19)17-9-4-3-7(5-8(9)13)12(14,15)16/h3-6,10,17H,1-2H3,(H,18,19)/t10-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Denmark Tau-fluvalinate 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate 07Jul2010 2010 doi:10.2903/j.efsa.2010.1645
+Tau-fluvalinate 102851-06-9 single chemical entity Component is a metabolite of the substance 3-{[2-chloro-4-(trifluoromethyl)phenyl]amino}-4-methyl-2-(3-phenoxyphenyl)pentanenitrile 3-{[2-chloro-4-(trifluoromethyl)phenyl]amino}-4-methyl-2-(3-phenoxyphenyl)pentanenitrile Not in list C25H22ClF3N2O Clc3cc(ccc3NC(C(C#N)c2cccc(Oc1ccccc1)c2)C(C)C)C(F)(F)F InChI=1/C25H22ClF3N2O/c1-16(2)24(31-23-12-11-18(14-22(23)26)25(27,28)29)21(15-30)17-7-6-10-20(13-17)32-19-8-4-3-5-9-19/h3-14,16,21,24,31H,1-2H3/t21?,24-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Denmark Tau-fluvalinate 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate 07Jul2010 2010 doi:10.2903/j.efsa.2010.1645
+Tau-fluvalinate 102851-06-9 single chemical entity Component is a metabolite of the substance 3-{[2-chloro-4-(trifluoromethyl)phenyl]amino}-4-methyl-2-(3-phenoxyphenyl)pentanenitrile 3-{[2-chloro-4-(trifluoromethyl)phenyl]amino}-4-methyl-2-(3-phenoxyphenyl)pentanenitrile Not in list C25H22ClF3N2O Clc3cc(ccc3NC(C(C#N)c2cccc(Oc1ccccc1)c2)C(C)C)C(F)(F)F InChI=1/C25H22ClF3N2O/c1-16(2)24(31-23-12-11-18(14-22(23)26)25(27,28)29)21(15-30)17-7-6-10-20(13-17)32-19-8-4-3-5-9-19/h3-14,16,21,24,31H,1-2H3/t21?,24-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Denmark Tau-fluvalinate 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate 07Jul2010 2010 doi:10.2903/j.efsa.2010.1645
+Tau-fluvalinate 102851-06-9 single chemical entity Component is a metabolite of the substance 3-{[2-chloro-4-(trifluoromethyl)phenyl]amino}-4-methyl-2-(3-phenoxyphenyl)pentanenitrile 3-{[2-chloro-4-(trifluoromethyl)phenyl]amino}-4-methyl-2-(3-phenoxyphenyl)pentanenitrile Not in list C25H22ClF3N2O Clc3cc(ccc3NC(C(C#N)c2cccc(Oc1ccccc1)c2)C(C)C)C(F)(F)F InChI=1/C25H22ClF3N2O/c1-16(2)24(31-23-12-11-18(14-22(23)26)25(27,28)29)21(15-30)17-7-6-10-20(13-17)32-19-8-4-3-5-9-19/h3-14,16,21,24,31H,1-2H3/t21?,24-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Denmark Tau-fluvalinate 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate 07Jul2010 2010 doi:10.2903/j.efsa.2010.1645
+Tau-fluvalinate 102851-06-9 single chemical entity Component is a metabolite of the substance 3-{[2-chloro-4-(trifluoromethyl)phenyl]amino}-4-methyl-2-(3-phenoxyphenyl)pentanenitrile 3-{[2-chloro-4-(trifluoromethyl)phenyl]amino}-4-methyl-2-(3-phenoxyphenyl)pentanenitrile Not in list C25H22ClF3N2O Clc3cc(ccc3NC(C(C#N)c2cccc(Oc1ccccc1)c2)C(C)C)C(F)(F)F InChI=1/C25H22ClF3N2O/c1-16(2)24(31-23-12-11-18(14-22(23)26)25(27,28)29)21(15-30)17-7-6-10-20(13-17)32-19-8-4-3-5-9-19/h3-14,16,21,24,31H,1-2H3/t21?,24-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Denmark Tau-fluvalinate 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate 07Jul2010 2010 doi:10.2903/j.efsa.2010.1645
+Tau-fluvalinate 102851-06-9 single chemical entity Component is a metabolite of the substance 3-{[2-chloro-4-(trifluoromethyl)phenyl]amino}-4-methyl-2-(3-phenoxyphenyl)pentanenitrile 3-{[2-chloro-4-(trifluoromethyl)phenyl]amino}-4-methyl-2-(3-phenoxyphenyl)pentanenitrile Not in list C25H22ClF3N2O Clc3cc(ccc3NC(C(C#N)c2cccc(Oc1ccccc1)c2)C(C)C)C(F)(F)F InChI=1/C25H22ClF3N2O/c1-16(2)24(31-23-12-11-18(14-22(23)26)25(27,28)29)21(15-30)17-7-6-10-20(13-17)32-19-8-4-3-5-9-19/h3-14,16,21,24,31H,1-2H3/t21?,24-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Denmark Tau-fluvalinate 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate 07Jul2010 2010 doi:10.2903/j.efsa.2010.1645
+Tau-fluvalinate 102851-06-9 single chemical entity Component is a metabolite of the substance 3-{[2-chloro-4-(trifluoromethyl)phenyl]amino}-4-methyl-2-(3-phenoxyphenyl)pentanenitrile 3-{[2-chloro-4-(trifluoromethyl)phenyl]amino}-4-methyl-2-(3-phenoxyphenyl)pentanenitrile Not in list C25H22ClF3N2O Clc3cc(ccc3NC(C(C#N)c2cccc(Oc1ccccc1)c2)C(C)C)C(F)(F)F InChI=1/C25H22ClF3N2O/c1-16(2)24(31-23-12-11-18(14-22(23)26)25(27,28)29)21(15-30)17-7-6-10-20(13-17)32-19-8-4-3-5-9-19/h3-14,16,21,24,31H,1-2H3/t21?,24-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Denmark Tau-fluvalinate 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate 07Jul2010 2010 doi:10.2903/j.efsa.2010.1645
+Tau-fluvalinate 102851-06-9 single chemical entity Component is a metabolite of the substance 3-{[2-chloro-4-(trifluoromethyl)phenyl]amino}-4-methyl-2-(3-phenoxyphenyl)pentanenitrile 3-{[2-chloro-4-(trifluoromethyl)phenyl]amino}-4-methyl-2-(3-phenoxyphenyl)pentanenitrile Not in list C25H22ClF3N2O Clc3cc(ccc3NC(C(C#N)c2cccc(Oc1ccccc1)c2)C(C)C)C(F)(F)F InChI=1/C25H22ClF3N2O/c1-16(2)24(31-23-12-11-18(14-22(23)26)25(27,28)29)21(15-30)17-7-6-10-20(13-17)32-19-8-4-3-5-9-19/h3-14,16,21,24,31H,1-2H3/t21?,24-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Denmark Tau-fluvalinate 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate 07Jul2010 2010 doi:10.2903/j.efsa.2010.1645
+Tau-fluvalinate 102851-06-9 single chemical entity Component is a metabolite of the substance 3-{[2-chloro-4-(trifluoromethyl)phenyl]amino}-4-methyl-2-(3-phenoxyphenyl)pentanenitrile 3-{[2-chloro-4-(trifluoromethyl)phenyl]amino}-4-methyl-2-(3-phenoxyphenyl)pentanenitrile Not in list C25H22ClF3N2O Clc3cc(ccc3NC(C(C#N)c2cccc(Oc1ccccc1)c2)C(C)C)C(F)(F)F InChI=1/C25H22ClF3N2O/c1-16(2)24(31-23-12-11-18(14-22(23)26)25(27,28)29)21(15-30)17-7-6-10-20(13-17)32-19-8-4-3-5-9-19/h3-14,16,21,24,31H,1-2H3/t21?,24-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Denmark Tau-fluvalinate 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate 07Jul2010 2010 doi:10.2903/j.efsa.2010.1645
+Tau-fluvalinate 102851-06-9 single chemical entity Component is a metabolite of the substance 3-{[2-chloro-4-(trifluoromethyl)phenyl]amino}-4-methyl-2-(3-phenoxyphenyl)pentanenitrile 3-{[2-chloro-4-(trifluoromethyl)phenyl]amino}-4-methyl-2-(3-phenoxyphenyl)pentanenitrile Not in list C25H22ClF3N2O Clc3cc(ccc3NC(C(C#N)c2cccc(Oc1ccccc1)c2)C(C)C)C(F)(F)F InChI=1/C25H22ClF3N2O/c1-16(2)24(31-23-12-11-18(14-22(23)26)25(27,28)29)21(15-30)17-7-6-10-20(13-17)32-19-8-4-3-5-9-19/h3-14,16,21,24,31H,1-2H3/t21?,24-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Denmark Tau-fluvalinate 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate 07Jul2010 2010 doi:10.2903/j.efsa.2010.1645
+Tau-fluvalinate 102851-06-9 single chemical entity Component is a metabolite of the substance 3-{[2-chloro-4-(trifluoromethyl)phenyl]amino}-4-methyl-2-(3-phenoxyphenyl)pentanenitrile 3-{[2-chloro-4-(trifluoromethyl)phenyl]amino}-4-methyl-2-(3-phenoxyphenyl)pentanenitrile Not in list C25H22ClF3N2O Clc3cc(ccc3NC(C(C#N)c2cccc(Oc1ccccc1)c2)C(C)C)C(F)(F)F InChI=1/C25H22ClF3N2O/c1-16(2)24(31-23-12-11-18(14-22(23)26)25(27,28)29)21(15-30)17-7-6-10-20(13-17)32-19-8-4-3-5-9-19/h3-14,16,21,24,31H,1-2H3/t21?,24-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Denmark Tau-fluvalinate 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate 07Jul2010 2010 doi:10.2903/j.efsa.2010.1645
+Tau-fluvalinate 102851-06-9 single chemical entity Component is a metabolite of the substance 3-{[2-chloro-4-(trifluoromethyl)phenyl]amino}-4-methyl-2-(3-phenoxyphenyl)pentanenitrile 3-{[2-chloro-4-(trifluoromethyl)phenyl]amino}-4-methyl-2-(3-phenoxyphenyl)pentanenitrile Not in list C25H22ClF3N2O Clc3cc(ccc3NC(C(C#N)c2cccc(Oc1ccccc1)c2)C(C)C)C(F)(F)F InChI=1/C25H22ClF3N2O/c1-16(2)24(31-23-12-11-18(14-22(23)26)25(27,28)29)21(15-30)17-7-6-10-20(13-17)32-19-8-4-3-5-9-19/h3-14,16,21,24,31H,1-2H3/t21?,24-/m0/s1 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Denmark Tau-fluvalinate 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate 07Jul2010 2010 doi:10.2903/j.efsa.2010.1645
+Tau-fluvalinate 102851-06-9 single chemical entity Component is a metabolite of the substance 3-{[2-chloro-4-(trifluoromethyl)phenyl]amino}-4-methyl-2-(3-phenoxyphenyl)pentanenitrile 3-{[2-chloro-4-(trifluoromethyl)phenyl]amino}-4-methyl-2-(3-phenoxyphenyl)pentanenitrile Not in list C25H22ClF3N2O Clc3cc(ccc3NC(C(C#N)c2cccc(Oc1ccccc1)c2)C(C)C)C(F)(F)F InChI=1/C25H22ClF3N2O/c1-16(2)24(31-23-12-11-18(14-22(23)26)25(27,28)29)21(15-30)17-7-6-10-20(13-17)32-19-8-4-3-5-9-19/h3-14,16,21,24,31H,1-2H3/t21?,24-/m0/s1 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Denmark Tau-fluvalinate 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate 07Jul2010 2010 doi:10.2903/j.efsa.2010.1645
+Sodium 5-nitroguaiacolate 67233-85-6 single chemical entity Component is identical to the substance Sodium 5-nitroguaiacolate 67233-85-6 Sodium;2-methoxy-5-nitrophenolate Not in list C7H6NNaO4 COC1=C(C=C(C=C1)[N+](=O)[O-])[O-].[Na+] InChI=1S/C7H7NO4.Na/c1-12-7-3-2-5(8(10)11)4-6(7)9;/h2-4,9H,1H3;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium 5-nitroguaiacolate 67233-85-6 single chemical entity Component is identical to the substance Sodium 5-nitroguaiacolate 67233-85-6 Sodium;2-methoxy-5-nitrophenolate Not in list C7H6NNaO4 COC1=C(C=C(C=C1)[N+](=O)[O-])[O-].[Na+] InChI=1S/C7H7NO4.Na/c1-12-7-3-2-5(8(10)11)4-6(7)9;/h2-4,9H,1H3;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium 5-nitroguaiacolate 67233-85-6 single chemical entity Component is identical to the substance Sodium 5-nitroguaiacolate 67233-85-6 Sodium;2-methoxy-5-nitrophenolate Not in list C7H6NNaO4 COC1=C(C=C(C=C1)[N+](=O)[O-])[O-].[Na+] InChI=1S/C7H7NO4.Na/c1-12-7-3-2-5(8(10)11)4-6(7)9;/h2-4,9H,1H3;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium 5-nitroguaiacolate 67233-85-6 single chemical entity Component is identical to the substance Sodium 5-nitroguaiacolate 67233-85-6 Sodium;2-methoxy-5-nitrophenolate Not in list C7H6NNaO4 COC1=C(C=C(C=C1)[N+](=O)[O-])[O-].[Na+] InChI=1S/C7H7NO4.Na/c1-12-7-3-2-5(8(10)11)4-6(7)9;/h2-4,9H,1H3;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium 5-nitroguaiacolate 67233-85-6 single chemical entity Component is identical to the substance Sodium 5-nitroguaiacolate 67233-85-6 Sodium;2-methoxy-5-nitrophenolate Not in list C7H6NNaO4 COC1=C(C=C(C=C1)[N+](=O)[O-])[O-].[Na+] InChI=1S/C7H7NO4.Na/c1-12-7-3-2-5(8(10)11)4-6(7)9;/h2-4,9H,1H3;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium 5-nitroguaiacolate 67233-85-6 single chemical entity Component is identical to the substance Sodium 5-nitroguaiacolate 67233-85-6 Sodium;2-methoxy-5-nitrophenolate Not in list C7H6NNaO4 COC1=C(C=C(C=C1)[N+](=O)[O-])[O-].[Na+] InChI=1S/C7H7NO4.Na/c1-12-7-3-2-5(8(10)11)4-6(7)9;/h2-4,9H,1H3;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium 5-nitroguaiacolate 67233-85-6 single chemical entity Component is identical to the substance Sodium 5-nitroguaiacolate 67233-85-6 Sodium;2-methoxy-5-nitrophenolate Not in list C7H6NNaO4 COC1=C(C=C(C=C1)[N+](=O)[O-])[O-].[Na+] InChI=1S/C7H7NO4.Na/c1-12-7-3-2-5(8(10)11)4-6(7)9;/h2-4,9H,1H3;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium 5-nitroguaiacolate 67233-85-6 single chemical entity Component is identical to the substance Sodium 5-nitroguaiacolate 67233-85-6 Sodium;2-methoxy-5-nitrophenolate Not in list C7H6NNaO4 COC1=C(C=C(C=C1)[N+](=O)[O-])[O-].[Na+] InChI=1S/C7H7NO4.Na/c1-12-7-3-2-5(8(10)11)4-6(7)9;/h2-4,9H,1H3;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium 5-nitroguaiacolate 67233-85-6 single chemical entity Component is identical to the substance Sodium 5-nitroguaiacolate 67233-85-6 Sodium;2-methoxy-5-nitrophenolate Not in list C7H6NNaO4 COC1=C(C=C(C=C1)[N+](=O)[O-])[O-].[Na+] InChI=1S/C7H7NO4.Na/c1-12-7-3-2-5(8(10)11)4-6(7)9;/h2-4,9H,1H3;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium 5-nitroguaiacolate 67233-85-6 single chemical entity Component is identical to the substance Sodium 5-nitroguaiacolate 67233-85-6 Sodium;2-methoxy-5-nitrophenolate Not in list C7H6NNaO4 COC1=C(C=C(C=C1)[N+](=O)[O-])[O-].[Na+] InChI=1S/C7H7NO4.Na/c1-12-7-3-2-5(8(10)11)4-6(7)9;/h2-4,9H,1H3;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium 5-nitroguaiacolate 67233-85-6 single chemical entity Component is identical to the substance Sodium 5-nitroguaiacolate 67233-85-6 Sodium;2-methoxy-5-nitrophenolate Not in list C7H6NNaO4 COC1=C(C=C(C=C1)[N+](=O)[O-])[O-].[Na+] InChI=1S/C7H7NO4.Na/c1-12-7-3-2-5(8(10)11)4-6(7)9;/h2-4,9H,1H3;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium 5-nitroguaiacolate 67233-85-6 single chemical entity Component is identical to the substance Sodium 5-nitroguaiacolate 67233-85-6 Sodium;2-methoxy-5-nitrophenolate Not in list C7H6NNaO4 COC1=C(C=C(C=C1)[N+](=O)[O-])[O-].[Na+] InChI=1S/C7H7NO4.Na/c1-12-7-3-2-5(8(10)11)4-6(7)9;/h2-4,9H,1H3;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium 5-nitroguaiacolate 67233-85-6 single chemical entity Component is identical to the substance Sodium 5-nitroguaiacolate 67233-85-6 Sodium;2-methoxy-5-nitrophenolate Not in list C7H6NNaO4 COC1=C(C=C(C=C1)[N+](=O)[O-])[O-].[Na+] InChI=1S/C7H7NO4.Na/c1-12-7-3-2-5(8(10)11)4-6(7)9;/h2-4,9H,1H3;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes, concurrent vehicle without Negative RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium 5-nitroguaiacolate 67233-85-6 single chemical entity Component is identical to the substance Sodium 5-nitroguaiacolate 67233-85-6 Sodium;2-methoxy-5-nitrophenolate Not in list C7H6NNaO4 COC1=C(C=C(C=C1)[N+](=O)[O-])[O-].[Na+] InChI=1S/C7H7NO4.Na/c1-12-7-3-2-5(8(10)11)4-6(7)9;/h2-4,9H,1H3;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes, concurrent vehicle without Negative RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium 5-nitroguaiacolate 67233-85-6 single chemical entity Component is identical to the substance Sodium 5-nitroguaiacolate 67233-85-6 Sodium;2-methoxy-5-nitrophenolate Not in list C7H6NNaO4 COC1=C(C=C(C=C1)[N+](=O)[O-])[O-].[Na+] InChI=1S/C7H7NO4.Na/c1-12-7-3-2-5(8(10)11)4-6(7)9;/h2-4,9H,1H3;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes, concurrent vehicle with Negative RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium 5-nitroguaiacolate 67233-85-6 single chemical entity Component is identical to the substance Sodium 5-nitroguaiacolate 67233-85-6 Sodium;2-methoxy-5-nitrophenolate Not in list C7H6NNaO4 COC1=C(C=C(C=C1)[N+](=O)[O-])[O-].[Na+] InChI=1S/C7H7NO4.Na/c1-12-7-3-2-5(8(10)11)4-6(7)9;/h2-4,9H,1H3;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes, concurrent vehicle with Negative RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium 5-nitroguaiacolate 67233-85-6 single chemical entity Component is identical to the substance Sodium 5-nitroguaiacolate 67233-85-6 Sodium;2-methoxy-5-nitrophenolate Not in list C7H6NNaO4 COC1=C(C=C(C=C1)[N+](=O)[O-])[O-].[Na+] InChI=1S/C7H7NO4.Na/c1-12-7-3-2-5(8(10)11)4-6(7)9;/h2-4,9H,1H3;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative no information RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium 5-nitroguaiacolate 67233-85-6 single chemical entity Component is identical to the substance Sodium 5-nitroguaiacolate 67233-85-6 Sodium;2-methoxy-5-nitrophenolate Not in list C7H6NNaO4 COC1=C(C=C(C=C1)[N+](=O)[O-])[O-].[Na+] InChI=1S/C7H7NO4.Na/c1-12-7-3-2-5(8(10)11)4-6(7)9;/h2-4,9H,1H3;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Positive no information RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium 5-nitroguaiacolate 67233-85-6 single chemical entity Component is identical to the substance Sodium 5-nitroguaiacolate 67233-85-6 Sodium;2-methoxy-5-nitrophenolate Not in list C7H6NNaO4 COC1=C(C=C(C=C1)[N+](=O)[O-])[O-].[Na+] InChI=1S/C7H7NO4.Na/c1-12-7-3-2-5(8(10)11)4-6(7)9;/h2-4,9H,1H3;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium 5-nitroguaiacolate 67233-85-6 single chemical entity Component is identical to the substance Sodium 5-nitroguaiacolate 67233-85-6 Sodium;2-methoxy-5-nitrophenolate Not in list C7H6NNaO4 COC1=C(C=C(C=C1)[N+](=O)[O-])[O-].[Na+] InChI=1S/C7H7NO4.Na/c1-12-7-3-2-5(8(10)11)4-6(7)9;/h2-4,9H,1H3;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium 5-nitroguaiacolate 67233-85-6 single chemical entity Component is identical to the substance Sodium 5-nitroguaiacolate 67233-85-6 Sodium;2-methoxy-5-nitrophenolate Not in list C7H6NNaO4 COC1=C(C=C(C=C1)[N+](=O)[O-])[O-].[Na+] InChI=1S/C7H7NO4.Na/c1-12-7-3-2-5(8(10)11)4-6(7)9;/h2-4,9H,1H3;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) ICR 10 Male/Female oral: gavage 72.0000000000 h yes not applicable Negative direct evidence-cytotoxicity RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium 5-nitroguaiacolate 67233-85-6 single chemical entity Component is identical to the substance Sodium 5-nitroguaiacolate 67233-85-6 Sodium;2-methoxy-5-nitrophenolate Not in list C7H6NNaO4 COC1=C(C=C(C=C1)[N+](=O)[O-])[O-].[Na+] InChI=1S/C7H7NO4.Na/c1-12-7-3-2-5(8(10)11)4-6(7)9;/h2-4,9H,1H3;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) ICR 10 Male/Female oral: gavage 48.0000000000 h yes not applicable Negative direct evidence-cytotoxicity RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium 5-nitroguaiacolate 67233-85-6 single chemical entity Component is identical to the substance Sodium 5-nitroguaiacolate 67233-85-6 Sodium;2-methoxy-5-nitrophenolate Not in list C7H6NNaO4 COC1=C(C=C(C=C1)[N+](=O)[O-])[O-].[Na+] InChI=1S/C7H7NO4.Na/c1-12-7-3-2-5(8(10)11)4-6(7)9;/h2-4,9H,1H3;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) ICR 10 Male/Female oral: gavage 24.0000000000 h yes not applicable Negative direct evidence-cytotoxicity RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium o-nitrophenolate 212-527-5 824-39-5 single chemical entity Component is identical to the substance Sodium o-nitrophenolate 212-527-5 824-39-5 Sodium;2-nitrophenolate Not in list C6H4NNaO3 C1=CC=C(C(=C1)[N+](=O)[O-])[O-].[Na+] InChI=1S/C6H5NO3.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium o-nitrophenolate 212-527-5 824-39-5 single chemical entity Component is identical to the substance Sodium o-nitrophenolate 212-527-5 824-39-5 Sodium;2-nitrophenolate Not in list C6H4NNaO3 C1=CC=C(C(=C1)[N+](=O)[O-])[O-].[Na+] InChI=1S/C6H5NO3.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium o-nitrophenolate 212-527-5 824-39-5 single chemical entity Component is identical to the substance Sodium o-nitrophenolate 212-527-5 824-39-5 Sodium;2-nitrophenolate Not in list C6H4NNaO3 C1=CC=C(C(=C1)[N+](=O)[O-])[O-].[Na+] InChI=1S/C6H5NO3.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium o-nitrophenolate 212-527-5 824-39-5 single chemical entity Component is identical to the substance Sodium o-nitrophenolate 212-527-5 824-39-5 Sodium;2-nitrophenolate Not in list C6H4NNaO3 C1=CC=C(C(=C1)[N+](=O)[O-])[O-].[Na+] InChI=1S/C6H5NO3.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium o-nitrophenolate 212-527-5 824-39-5 single chemical entity Component is identical to the substance Sodium o-nitrophenolate 212-527-5 824-39-5 Sodium;2-nitrophenolate Not in list C6H4NNaO3 C1=CC=C(C(=C1)[N+](=O)[O-])[O-].[Na+] InChI=1S/C6H5NO3.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium o-nitrophenolate 212-527-5 824-39-5 single chemical entity Component is identical to the substance Sodium o-nitrophenolate 212-527-5 824-39-5 Sodium;2-nitrophenolate Not in list C6H4NNaO3 C1=CC=C(C(=C1)[N+](=O)[O-])[O-].[Na+] InChI=1S/C6H5NO3.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium o-nitrophenolate 212-527-5 824-39-5 single chemical entity Component is identical to the substance Sodium o-nitrophenolate 212-527-5 824-39-5 Sodium;2-nitrophenolate Not in list C6H4NNaO3 C1=CC=C(C(=C1)[N+](=O)[O-])[O-].[Na+] InChI=1S/C6H5NO3.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium o-nitrophenolate 212-527-5 824-39-5 single chemical entity Component is identical to the substance Sodium o-nitrophenolate 212-527-5 824-39-5 Sodium;2-nitrophenolate Not in list C6H4NNaO3 C1=CC=C(C(=C1)[N+](=O)[O-])[O-].[Na+] InChI=1S/C6H5NO3.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium o-nitrophenolate 212-527-5 824-39-5 single chemical entity Component is identical to the substance Sodium o-nitrophenolate 212-527-5 824-39-5 Sodium;2-nitrophenolate Not in list C6H4NNaO3 C1=CC=C(C(=C1)[N+](=O)[O-])[O-].[Na+] InChI=1S/C6H5NO3.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium o-nitrophenolate 212-527-5 824-39-5 single chemical entity Component is identical to the substance Sodium o-nitrophenolate 212-527-5 824-39-5 Sodium;2-nitrophenolate Not in list C6H4NNaO3 C1=CC=C(C(=C1)[N+](=O)[O-])[O-].[Na+] InChI=1S/C6H5NO3.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium o-nitrophenolate 212-527-5 824-39-5 single chemical entity Component is identical to the substance Sodium o-nitrophenolate 212-527-5 824-39-5 Sodium;2-nitrophenolate Not in list C6H4NNaO3 C1=CC=C(C(=C1)[N+](=O)[O-])[O-].[Na+] InChI=1S/C6H5NO3.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium o-nitrophenolate 212-527-5 824-39-5 single chemical entity Component is identical to the substance Sodium o-nitrophenolate 212-527-5 824-39-5 Sodium;2-nitrophenolate Not in list C6H4NNaO3 C1=CC=C(C(=C1)[N+](=O)[O-])[O-].[Na+] InChI=1S/C6H5NO3.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium o-nitrophenolate 212-527-5 824-39-5 single chemical entity Component is identical to the substance Sodium o-nitrophenolate 212-527-5 824-39-5 Sodium;2-nitrophenolate Not in list C6H4NNaO3 C1=CC=C(C(=C1)[N+](=O)[O-])[O-].[Na+] InChI=1S/C6H5NO3.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes, concurrent vehicle without Negative RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium o-nitrophenolate 212-527-5 824-39-5 single chemical entity Component is identical to the substance Sodium o-nitrophenolate 212-527-5 824-39-5 Sodium;2-nitrophenolate Not in list C6H4NNaO3 C1=CC=C(C(=C1)[N+](=O)[O-])[O-].[Na+] InChI=1S/C6H5NO3.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes, concurrent vehicle with Negative RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium o-nitrophenolate 212-527-5 824-39-5 single chemical entity Component is identical to the substance Sodium o-nitrophenolate 212-527-5 824-39-5 Sodium;2-nitrophenolate Not in list C6H4NNaO3 C1=CC=C(C(=C1)[N+](=O)[O-])[O-].[Na+] InChI=1S/C6H5NO3.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes, concurrent vehicle with Negative RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium o-nitrophenolate 212-527-5 824-39-5 single chemical entity Component is identical to the substance Sodium o-nitrophenolate 212-527-5 824-39-5 Sodium;2-nitrophenolate Not in list C6H4NNaO3 C1=CC=C(C(=C1)[N+](=O)[O-])[O-].[Na+] InChI=1S/C6H5NO3.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes, concurrent vehicle without Negative RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium o-nitrophenolate 212-527-5 824-39-5 single chemical entity Component is identical to the substance Sodium o-nitrophenolate 212-527-5 824-39-5 Sodium;2-nitrophenolate Not in list C6H4NNaO3 C1=CC=C(C(=C1)[N+](=O)[O-])[O-].[Na+] InChI=1S/C6H5NO3.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative no information RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium o-nitrophenolate 212-527-5 824-39-5 single chemical entity Component is identical to the substance Sodium o-nitrophenolate 212-527-5 824-39-5 Sodium;2-nitrophenolate Not in list C6H4NNaO3 C1=CC=C(C(=C1)[N+](=O)[O-])[O-].[Na+] InChI=1S/C6H5NO3.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Negative no information RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium o-nitrophenolate 212-527-5 824-39-5 single chemical entity Component is identical to the substance Sodium o-nitrophenolate 212-527-5 824-39-5 Sodium;2-nitrophenolate Not in list C6H4NNaO3 C1=CC=C(C(=C1)[N+](=O)[O-])[O-].[Na+] InChI=1S/C6H5NO3.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium o-nitrophenolate 212-527-5 824-39-5 single chemical entity Component is identical to the substance Sodium o-nitrophenolate 212-527-5 824-39-5 Sodium;2-nitrophenolate Not in list C6H4NNaO3 C1=CC=C(C(=C1)[N+](=O)[O-])[O-].[Na+] InChI=1S/C6H5NO3.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium o-nitrophenolate 212-527-5 824-39-5 single chemical entity Component is identical to the substance Sodium o-nitrophenolate 212-527-5 824-39-5 Sodium;2-nitrophenolate Not in list C6H4NNaO3 C1=CC=C(C(=C1)[N+](=O)[O-])[O-].[Na+] InChI=1S/C6H5NO3.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) ICR 10 Male/Female intraperitoneal 72.0000000000 h yes not applicable Negative no evidence RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium o-nitrophenolate 212-527-5 824-39-5 single chemical entity Component is identical to the substance Sodium o-nitrophenolate 212-527-5 824-39-5 Sodium;2-nitrophenolate Not in list C6H4NNaO3 C1=CC=C(C(=C1)[N+](=O)[O-])[O-].[Na+] InChI=1S/C6H5NO3.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) ICR 10 Male/Female intraperitoneal 48.0000000000 h yes not applicable Negative no evidence RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium o-nitrophenolate 212-527-5 824-39-5 single chemical entity Component is identical to the substance Sodium o-nitrophenolate 212-527-5 824-39-5 Sodium;2-nitrophenolate Not in list C6H4NNaO3 C1=CC=C(C(=C1)[N+](=O)[O-])[O-].[Na+] InChI=1S/C6H5NO3.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) ICR 10 Male/Female intraperitoneal 24.0000000000 h yes not applicable Negative no evidence RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium p-nitrophenolate 212-536-4 824-78-2 single chemical entity Component is identical to the substance Sodium p-nitrophenolate 212-536-4 824-78-2 Sodium;4-nitrophenolate Not in list C6H4NNaO3 C1=CC(=CC=C1[N+](=O)[O-])[O-].[Na+] InChI=1S/C6H5NO3.Na/c8-6-3-1-5(2-4-6)7(9)10;/h1-4,8H;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium p-nitrophenolate 212-536-4 824-78-2 single chemical entity Component is identical to the substance Sodium p-nitrophenolate 212-536-4 824-78-2 Sodium;4-nitrophenolate Not in list C6H4NNaO3 C1=CC(=CC=C1[N+](=O)[O-])[O-].[Na+] InChI=1S/C6H5NO3.Na/c8-6-3-1-5(2-4-6)7(9)10;/h1-4,8H;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium p-nitrophenolate 212-536-4 824-78-2 single chemical entity Component is identical to the substance Sodium p-nitrophenolate 212-536-4 824-78-2 Sodium;4-nitrophenolate Not in list C6H4NNaO3 C1=CC(=CC=C1[N+](=O)[O-])[O-].[Na+] InChI=1S/C6H5NO3.Na/c8-6-3-1-5(2-4-6)7(9)10;/h1-4,8H;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium p-nitrophenolate 212-536-4 824-78-2 single chemical entity Component is identical to the substance Sodium p-nitrophenolate 212-536-4 824-78-2 Sodium;4-nitrophenolate Not in list C6H4NNaO3 C1=CC(=CC=C1[N+](=O)[O-])[O-].[Na+] InChI=1S/C6H5NO3.Na/c8-6-3-1-5(2-4-6)7(9)10;/h1-4,8H;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium p-nitrophenolate 212-536-4 824-78-2 single chemical entity Component is identical to the substance Sodium p-nitrophenolate 212-536-4 824-78-2 Sodium;4-nitrophenolate Not in list C6H4NNaO3 C1=CC(=CC=C1[N+](=O)[O-])[O-].[Na+] InChI=1S/C6H5NO3.Na/c8-6-3-1-5(2-4-6)7(9)10;/h1-4,8H;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium p-nitrophenolate 212-536-4 824-78-2 single chemical entity Component is identical to the substance Sodium p-nitrophenolate 212-536-4 824-78-2 Sodium;4-nitrophenolate Not in list C6H4NNaO3 C1=CC(=CC=C1[N+](=O)[O-])[O-].[Na+] InChI=1S/C6H5NO3.Na/c8-6-3-1-5(2-4-6)7(9)10;/h1-4,8H;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium p-nitrophenolate 212-536-4 824-78-2 single chemical entity Component is identical to the substance Sodium p-nitrophenolate 212-536-4 824-78-2 Sodium;4-nitrophenolate Not in list C6H4NNaO3 C1=CC(=CC=C1[N+](=O)[O-])[O-].[Na+] InChI=1S/C6H5NO3.Na/c8-6-3-1-5(2-4-6)7(9)10;/h1-4,8H;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium p-nitrophenolate 212-536-4 824-78-2 single chemical entity Component is identical to the substance Sodium p-nitrophenolate 212-536-4 824-78-2 Sodium;4-nitrophenolate Not in list C6H4NNaO3 C1=CC(=CC=C1[N+](=O)[O-])[O-].[Na+] InChI=1S/C6H5NO3.Na/c8-6-3-1-5(2-4-6)7(9)10;/h1-4,8H;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium p-nitrophenolate 212-536-4 824-78-2 single chemical entity Component is identical to the substance Sodium p-nitrophenolate 212-536-4 824-78-2 Sodium;4-nitrophenolate Not in list C6H4NNaO3 C1=CC(=CC=C1[N+](=O)[O-])[O-].[Na+] InChI=1S/C6H5NO3.Na/c8-6-3-1-5(2-4-6)7(9)10;/h1-4,8H;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium p-nitrophenolate 212-536-4 824-78-2 single chemical entity Component is identical to the substance Sodium p-nitrophenolate 212-536-4 824-78-2 Sodium;4-nitrophenolate Not in list C6H4NNaO3 C1=CC(=CC=C1[N+](=O)[O-])[O-].[Na+] InChI=1S/C6H5NO3.Na/c8-6-3-1-5(2-4-6)7(9)10;/h1-4,8H;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium p-nitrophenolate 212-536-4 824-78-2 single chemical entity Component is identical to the substance Sodium p-nitrophenolate 212-536-4 824-78-2 Sodium;4-nitrophenolate Not in list C6H4NNaO3 C1=CC(=CC=C1[N+](=O)[O-])[O-].[Na+] InChI=1S/C6H5NO3.Na/c8-6-3-1-5(2-4-6)7(9)10;/h1-4,8H;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium p-nitrophenolate 212-536-4 824-78-2 single chemical entity Component is identical to the substance Sodium p-nitrophenolate 212-536-4 824-78-2 Sodium;4-nitrophenolate Not in list C6H4NNaO3 C1=CC(=CC=C1[N+](=O)[O-])[O-].[Na+] InChI=1S/C6H5NO3.Na/c8-6-3-1-5(2-4-6)7(9)10;/h1-4,8H;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium p-nitrophenolate 212-536-4 824-78-2 single chemical entity Component is identical to the substance Sodium p-nitrophenolate 212-536-4 824-78-2 Sodium;4-nitrophenolate Not in list C6H4NNaO3 C1=CC(=CC=C1[N+](=O)[O-])[O-].[Na+] InChI=1S/C6H5NO3.Na/c8-6-3-1-5(2-4-6)7(9)10;/h1-4,8H;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes, concurrent vehicle without Negative RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium p-nitrophenolate 212-536-4 824-78-2 single chemical entity Component is identical to the substance Sodium p-nitrophenolate 212-536-4 824-78-2 Sodium;4-nitrophenolate Not in list C6H4NNaO3 C1=CC(=CC=C1[N+](=O)[O-])[O-].[Na+] InChI=1S/C6H5NO3.Na/c8-6-3-1-5(2-4-6)7(9)10;/h1-4,8H;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes, concurrent vehicle without Negative RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium p-nitrophenolate 212-536-4 824-78-2 single chemical entity Component is identical to the substance Sodium p-nitrophenolate 212-536-4 824-78-2 Sodium;4-nitrophenolate Not in list C6H4NNaO3 C1=CC(=CC=C1[N+](=O)[O-])[O-].[Na+] InChI=1S/C6H5NO3.Na/c8-6-3-1-5(2-4-6)7(9)10;/h1-4,8H;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes, concurrent vehicle with Negative RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium p-nitrophenolate 212-536-4 824-78-2 single chemical entity Component is identical to the substance Sodium p-nitrophenolate 212-536-4 824-78-2 Sodium;4-nitrophenolate Not in list C6H4NNaO3 C1=CC(=CC=C1[N+](=O)[O-])[O-].[Na+] InChI=1S/C6H5NO3.Na/c8-6-3-1-5(2-4-6)7(9)10;/h1-4,8H;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes, concurrent vehicle with Negative RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium p-nitrophenolate 212-536-4 824-78-2 single chemical entity Component is identical to the substance Sodium p-nitrophenolate 212-536-4 824-78-2 Sodium;4-nitrophenolate Not in list C6H4NNaO3 C1=CC(=CC=C1[N+](=O)[O-])[O-].[Na+] InChI=1S/C6H5NO3.Na/c8-6-3-1-5(2-4-6)7(9)10;/h1-4,8H;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Positive small colonies RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium p-nitrophenolate 212-536-4 824-78-2 single chemical entity Component is identical to the substance Sodium p-nitrophenolate 212-536-4 824-78-2 Sodium;4-nitrophenolate Not in list C6H4NNaO3 C1=CC(=CC=C1[N+](=O)[O-])[O-].[Na+] InChI=1S/C6H5NO3.Na/c8-6-3-1-5(2-4-6)7(9)10;/h1-4,8H;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Positive small colonies RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium p-nitrophenolate 212-536-4 824-78-2 single chemical entity Component is identical to the substance Sodium p-nitrophenolate 212-536-4 824-78-2 Sodium;4-nitrophenolate Not in list C6H4NNaO3 C1=CC(=CC=C1[N+](=O)[O-])[O-].[Na+] InChI=1S/C6H5NO3.Na/c8-6-3-1-5(2-4-6)7(9)10;/h1-4,8H;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium p-nitrophenolate 212-536-4 824-78-2 single chemical entity Component is identical to the substance Sodium p-nitrophenolate 212-536-4 824-78-2 Sodium;4-nitrophenolate Not in list C6H4NNaO3 C1=CC(=CC=C1[N+](=O)[O-])[O-].[Na+] InChI=1S/C6H5NO3.Na/c8-6-3-1-5(2-4-6)7(9)10;/h1-4,8H;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium p-nitrophenolate 212-536-4 824-78-2 single chemical entity Component is identical to the substance Sodium p-nitrophenolate 212-536-4 824-78-2 Sodium;4-nitrophenolate Not in list C6H4NNaO3 C1=CC(=CC=C1[N+](=O)[O-])[O-].[Na+] InChI=1S/C6H5NO3.Na/c8-6-3-1-5(2-4-6)7(9)10;/h1-4,8H;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) ICR 10 Male/Female intraperitoneal 48.0000000000 h yes not applicable Negative no evidence RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium p-nitrophenolate 212-536-4 824-78-2 single chemical entity Component is identical to the substance Sodium p-nitrophenolate 212-536-4 824-78-2 Sodium;4-nitrophenolate Not in list C6H4NNaO3 C1=CC(=CC=C1[N+](=O)[O-])[O-].[Na+] InChI=1S/C6H5NO3.Na/c8-6-3-1-5(2-4-6)7(9)10;/h1-4,8H;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) ICR 10 Male/Female intraperitoneal 72.0000000000 h yes not applicable Negative no evidence RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Sodium p-nitrophenolate 212-536-4 824-78-2 single chemical entity Component is identical to the substance Sodium p-nitrophenolate 212-536-4 824-78-2 Sodium;4-nitrophenolate Not in list C6H4NNaO3 C1=CC(=CC=C1[N+](=O)[O-])[O-].[Na+] InChI=1S/C6H5NO3.Na/c8-6-3-1-5(2-4-6)7(9)10;/h1-4,8H;/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) ICR 10 Male/Female intraperitoneal 24.0000000000 h yes not applicable Negative no evidence RMS: Greece Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. 01Apr2009 2009 doi:10.2903/j.efsa.2009.191r
+Spirodiclofen 148477-71-8 single chemical entity Component is identical to the substance Spirodiclofen 148477-71-8 3-(3,5-dichlorophenyl)-2-oxo-1-oxaspiro[4.5]dec-3-en-4-yl 2,2-dimethylbutanoate Spirodiclofen C21H24Cl2O4 O=C2OC1(C(OC(C(CC)(C)C)=O)=C2C3=CC(Cl)=CC(Cl)=C3)CCCCC1 InChI=1S/C21H24Cl2O4/c1-4-20(2,3)19(25)26-17-16(13-10-14(22)12-15(23)11-13)18(24)27-21(17)8-6-5-7-9-21/h10-12H,4-9H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Spirodiclofen 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance spirodiclofen 06Aug2009 2009 doi:10.2903/j.efsa.2009.339r
+Spirodiclofen 148477-71-8 single chemical entity Component is identical to the substance Spirodiclofen 148477-71-8 3-(3,5-dichlorophenyl)-2-oxo-1-oxaspiro[4.5]dec-3-en-4-yl 2,2-dimethylbutanoate Spirodiclofen C21H24Cl2O4 O=C2OC1(C(OC(C(CC)(C)C)=O)=C2C3=CC(Cl)=CC(Cl)=C3)CCCCC1 InChI=1S/C21H24Cl2O4/c1-4-20(2,3)19(25)26-17-16(13-10-14(22)12-15(23)11-13)18(24)27-21(17)8-6-5-7-9-21/h10-12H,4-9H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Spirodiclofen 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance spirodiclofen 06Aug2009 2009 doi:10.2903/j.efsa.2009.339r
+Spirodiclofen 148477-71-8 single chemical entity Component is identical to the substance Spirodiclofen 148477-71-8 3-(3,5-dichlorophenyl)-2-oxo-1-oxaspiro[4.5]dec-3-en-4-yl 2,2-dimethylbutanoate Spirodiclofen C21H24Cl2O4 O=C2OC1(C(OC(C(CC)(C)C)=O)=C2C3=CC(Cl)=CC(Cl)=C3)CCCCC1 InChI=1S/C21H24Cl2O4/c1-4-20(2,3)19(25)26-17-16(13-10-14(22)12-15(23)11-13)18(24)27-21(17)8-6-5-7-9-21/h10-12H,4-9H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Spirodiclofen 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance spirodiclofen 06Aug2009 2009 doi:10.2903/j.efsa.2009.339r
+Spirodiclofen 148477-71-8 single chemical entity Component is identical to the substance Spirodiclofen 148477-71-8 3-(3,5-dichlorophenyl)-2-oxo-1-oxaspiro[4.5]dec-3-en-4-yl 2,2-dimethylbutanoate Spirodiclofen C21H24Cl2O4 O=C2OC1(C(OC(C(CC)(C)C)=O)=C2C3=CC(Cl)=CC(Cl)=C3)CCCCC1 InChI=1S/C21H24Cl2O4/c1-4-20(2,3)19(25)26-17-16(13-10-14(22)12-15(23)11-13)18(24)27-21(17)8-6-5-7-9-21/h10-12H,4-9H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Spirodiclofen 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance spirodiclofen 06Aug2009 2009 doi:10.2903/j.efsa.2009.339r
+Spirodiclofen 148477-71-8 single chemical entity Component is identical to the substance Spirodiclofen 148477-71-8 3-(3,5-dichlorophenyl)-2-oxo-1-oxaspiro[4.5]dec-3-en-4-yl 2,2-dimethylbutanoate Spirodiclofen C21H24Cl2O4 O=C2OC1(C(OC(C(CC)(C)C)=O)=C2C3=CC(Cl)=CC(Cl)=C3)CCCCC1 InChI=1S/C21H24Cl2O4/c1-4-20(2,3)19(25)26-17-16(13-10-14(22)12-15(23)11-13)18(24)27-21(17)8-6-5-7-9-21/h10-12H,4-9H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Spirodiclofen 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance spirodiclofen 06Aug2009 2009 doi:10.2903/j.efsa.2009.339r
+Spirodiclofen 148477-71-8 single chemical entity Component is identical to the substance Spirodiclofen 148477-71-8 3-(3,5-dichlorophenyl)-2-oxo-1-oxaspiro[4.5]dec-3-en-4-yl 2,2-dimethylbutanoate Spirodiclofen C21H24Cl2O4 O=C2OC1(C(OC(C(CC)(C)C)=O)=C2C3=CC(Cl)=CC(Cl)=C3)CCCCC1 InChI=1S/C21H24Cl2O4/c1-4-20(2,3)19(25)26-17-16(13-10-14(22)12-15(23)11-13)18(24)27-21(17)8-6-5-7-9-21/h10-12H,4-9H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Spirodiclofen 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance spirodiclofen 06Aug2009 2009 doi:10.2903/j.efsa.2009.339r
+Spirodiclofen 148477-71-8 single chemical entity Component is identical to the substance Spirodiclofen 148477-71-8 3-(3,5-dichlorophenyl)-2-oxo-1-oxaspiro[4.5]dec-3-en-4-yl 2,2-dimethylbutanoate Spirodiclofen C21H24Cl2O4 O=C2OC1(C(OC(C(CC)(C)C)=O)=C2C3=CC(Cl)=CC(Cl)=C3)CCCCC1 InChI=1S/C21H24Cl2O4/c1-4-20(2,3)19(25)26-17-16(13-10-14(22)12-15(23)11-13)18(24)27-21(17)8-6-5-7-9-21/h10-12H,4-9H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Spirodiclofen 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance spirodiclofen 06Aug2009 2009 doi:10.2903/j.efsa.2009.339r
+Spirodiclofen 148477-71-8 single chemical entity Component is identical to the substance Spirodiclofen 148477-71-8 3-(3,5-dichlorophenyl)-2-oxo-1-oxaspiro[4.5]dec-3-en-4-yl 2,2-dimethylbutanoate Spirodiclofen C21H24Cl2O4 O=C2OC1(C(OC(C(CC)(C)C)=O)=C2C3=CC(Cl)=CC(Cl)=C3)CCCCC1 InChI=1S/C21H24Cl2O4/c1-4-20(2,3)19(25)26-17-16(13-10-14(22)12-15(23)11-13)18(24)27-21(17)8-6-5-7-9-21/h10-12H,4-9H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Spirodiclofen 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance spirodiclofen 06Aug2009 2009 doi:10.2903/j.efsa.2009.339r
+Spirodiclofen 148477-71-8 single chemical entity Component is identical to the substance Spirodiclofen 148477-71-8 3-(3,5-dichlorophenyl)-2-oxo-1-oxaspiro[4.5]dec-3-en-4-yl 2,2-dimethylbutanoate Spirodiclofen C21H24Cl2O4 O=C2OC1(C(OC(C(CC)(C)C)=O)=C2C3=CC(Cl)=CC(Cl)=C3)CCCCC1 InChI=1S/C21H24Cl2O4/c1-4-20(2,3)19(25)26-17-16(13-10-14(22)12-15(23)11-13)18(24)27-21(17)8-6-5-7-9-21/h10-12H,4-9H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Spirodiclofen 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance spirodiclofen 06Aug2009 2009 doi:10.2903/j.efsa.2009.339r
+Spirodiclofen 148477-71-8 single chemical entity Component is identical to the substance Spirodiclofen 148477-71-8 3-(3,5-dichlorophenyl)-2-oxo-1-oxaspiro[4.5]dec-3-en-4-yl 2,2-dimethylbutanoate Spirodiclofen C21H24Cl2O4 O=C2OC1(C(OC(C(CC)(C)C)=O)=C2C3=CC(Cl)=CC(Cl)=C3)CCCCC1 InChI=1S/C21H24Cl2O4/c1-4-20(2,3)19(25)26-17-16(13-10-14(22)12-15(23)11-13)18(24)27-21(17)8-6-5-7-9-21/h10-12H,4-9H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Spirodiclofen 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance spirodiclofen 06Aug2009 2009 doi:10.2903/j.efsa.2009.339r
+Spirodiclofen 148477-71-8 single chemical entity Component is identical to the substance Spirodiclofen 148477-71-8 3-(3,5-dichlorophenyl)-2-oxo-1-oxaspiro[4.5]dec-3-en-4-yl 2,2-dimethylbutanoate Spirodiclofen C21H24Cl2O4 O=C2OC1(C(OC(C(CC)(C)C)=O)=C2C3=CC(Cl)=CC(Cl)=C3)CCCCC1 InChI=1S/C21H24Cl2O4/c1-4-20(2,3)19(25)26-17-16(13-10-14(22)12-15(23)11-13)18(24)27-21(17)8-6-5-7-9-21/h10-12H,4-9H2,1-3H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Spirodiclofen 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance spirodiclofen 06Aug2009 2009 doi:10.2903/j.efsa.2009.339r
+Spirodiclofen 148477-71-8 single chemical entity Component is identical to the substance Spirodiclofen 148477-71-8 3-(3,5-dichlorophenyl)-2-oxo-1-oxaspiro[4.5]dec-3-en-4-yl 2,2-dimethylbutanoate Spirodiclofen C21H24Cl2O4 O=C2OC1(C(OC(C(CC)(C)C)=O)=C2C3=CC(Cl)=CC(Cl)=C3)CCCCC1 InChI=1S/C21H24Cl2O4/c1-4-20(2,3)19(25)26-17-16(13-10-14(22)12-15(23)11-13)18(24)27-21(17)8-6-5-7-9-21/h10-12H,4-9H2,1-3H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Spirodiclofen 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance spirodiclofen 06Aug2009 2009 doi:10.2903/j.efsa.2009.339r
+Spirodiclofen 148477-71-8 single chemical entity Component is identical to the substance Spirodiclofen 148477-71-8 3-(3,5-dichlorophenyl)-2-oxo-1-oxaspiro[4.5]dec-3-en-4-yl 2,2-dimethylbutanoate Spirodiclofen C21H24Cl2O4 O=C2OC1(C(OC(C(CC)(C)C)=O)=C2C3=CC(Cl)=CC(Cl)=C3)CCCCC1 InChI=1S/C21H24Cl2O4/c1-4-20(2,3)19(25)26-17-16(13-10-14(22)12-15(23)11-13)18(24)27-21(17)8-6-5-7-9-21/h10-12H,4-9H2,1-3H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Ambiguous RMS: The Netherlands Spirodiclofen 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance spirodiclofen 06Aug2009 2009 doi:10.2903/j.efsa.2009.339r
+Spirodiclofen 148477-71-8 single chemical entity Component is identical to the substance Spirodiclofen 148477-71-8 3-(3,5-dichlorophenyl)-2-oxo-1-oxaspiro[4.5]dec-3-en-4-yl 2,2-dimethylbutanoate Spirodiclofen C21H24Cl2O4 O=C2OC1(C(OC(C(CC)(C)C)=O)=C2C3=CC(Cl)=CC(Cl)=C3)CCCCC1 InChI=1S/C21H24Cl2O4/c1-4-20(2,3)19(25)26-17-16(13-10-14(22)12-15(23)11-13)18(24)27-21(17)8-6-5-7-9-21/h10-12H,4-9H2,1-3H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Ambiguous RMS: The Netherlands Spirodiclofen 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance spirodiclofen 06Aug2009 2009 doi:10.2903/j.efsa.2009.339r
+Spirodiclofen 148477-71-8 single chemical entity Component is identical to the substance Spirodiclofen 148477-71-8 3-(3,5-dichlorophenyl)-2-oxo-1-oxaspiro[4.5]dec-3-en-4-yl 2,2-dimethylbutanoate Spirodiclofen C21H24Cl2O4 O=C2OC1(C(OC(C(CC)(C)C)=O)=C2C3=CC(Cl)=CC(Cl)=C3)CCCCC1 InChI=1S/C21H24Cl2O4/c1-4-20(2,3)19(25)26-17-16(13-10-14(22)12-15(23)11-13)18(24)27-21(17)8-6-5-7-9-21/h10-12H,4-9H2,1-3H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Not reported 10 Male/Female intraperitoneal 48.0000000000 h yes not applicable Negative direct evidence-cytotoxicity RMS: The Netherlands Spirodiclofen 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance spirodiclofen 06Aug2009 2009 doi:10.2903/j.efsa.2009.339r
+Spirodiclofen 148477-71-8 single chemical entity Component is identical to the substance Spirodiclofen 148477-71-8 3-(3,5-dichlorophenyl)-2-oxo-1-oxaspiro[4.5]dec-3-en-4-yl 2,2-dimethylbutanoate Spirodiclofen C21H24Cl2O4 O=C2OC1(C(OC(C(CC)(C)C)=O)=C2C3=CC(Cl)=CC(Cl)=C3)CCCCC1 InChI=1S/C21H24Cl2O4/c1-4-20(2,3)19(25)26-17-16(13-10-14(22)12-15(23)11-13)18(24)27-21(17)8-6-5-7-9-21/h10-12H,4-9H2,1-3H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Not reported 10 Male/Female intraperitoneal 24.0000000000 h yes not applicable Negative direct evidence-cytotoxicity RMS: The Netherlands Spirodiclofen 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance spirodiclofen 06Aug2009 2009 doi:10.2903/j.efsa.2009.339r
+Spirodiclofen 148477-71-8 single chemical entity Component is identical to the substance Spirodiclofen 148477-71-8 3-(3,5-dichlorophenyl)-2-oxo-1-oxaspiro[4.5]dec-3-en-4-yl 2,2-dimethylbutanoate Spirodiclofen C21H24Cl2O4 O=C2OC1(C(OC(C(CC)(C)C)=O)=C2C3=CC(Cl)=CC(Cl)=C3)CCCCC1 InChI=1S/C21H24Cl2O4/c1-4-20(2,3)19(25)26-17-16(13-10-14(22)12-15(23)11-13)18(24)27-21(17)8-6-5-7-9-21/h10-12H,4-9H2,1-3H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Not reported 10 Male/Female intraperitoneal 16.0000000000 h yes not applicable Negative direct evidence-cytotoxicity RMS: The Netherlands Spirodiclofen 2004 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance spirodiclofen 06Aug2009 2009 doi:10.2903/j.efsa.2009.339r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is a metabolite of the substance 4-Hydroxymethyl-DMST-glucoside N,N-dimethyl-N´-[(4-(ß-D-glucopyranosyl)-methylphenyl]sulfamide Not in list C16H26N2O8S CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2 InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is a metabolite of the substance 4-Hydroxymethyl-DMST-glucoside N,N-dimethyl-N´-[(4-(ß-D-glucopyranosyl)-methylphenyl]sulfamide Not in list C16H26N2O8S CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2 InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is a metabolite of the substance 4-Hydroxymethyl-DMST-glucoside N,N-dimethyl-N´-[(4-(ß-D-glucopyranosyl)-methylphenyl]sulfamide Not in list C16H26N2O8S CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2 InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is a metabolite of the substance 4-Hydroxymethyl-DMST-glucoside N,N-dimethyl-N´-[(4-(ß-D-glucopyranosyl)-methylphenyl]sulfamide Not in list C16H26N2O8S CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2 InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is a metabolite of the substance 4-Hydroxymethyl-DMST-glucoside N,N-dimethyl-N´-[(4-(ß-D-glucopyranosyl)-methylphenyl]sulfamide Not in list C16H26N2O8S CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2 InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is a metabolite of the substance 4-Hydroxymethyl-DMST-glucoside N,N-dimethyl-N´-[(4-(ß-D-glucopyranosyl)-methylphenyl]sulfamide Not in list C16H26N2O8S CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2 InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is a metabolite of the substance 4-Hydroxymethyl-DMST-glucoside N,N-dimethyl-N´-[(4-(ß-D-glucopyranosyl)-methylphenyl]sulfamide Not in list C16H26N2O8S CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2 InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is a metabolite of the substance 4-Hydroxymethyl-DMST-glucoside N,N-dimethyl-N´-[(4-(ß-D-glucopyranosyl)-methylphenyl]sulfamide Not in list C16H26N2O8S CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2 InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is identical to the substance Tolylfluanid 211-986-9 731-27-1 N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline Tolylfluanid C10H13Cl2FN2O2S2 CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is identical to the substance Tolylfluanid 211-986-9 731-27-1 N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline Tolylfluanid C10H13Cl2FN2O2S2 CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is identical to the substance Tolylfluanid 211-986-9 731-27-1 N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline Tolylfluanid C10H13Cl2FN2O2S2 CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is identical to the substance Tolylfluanid 211-986-9 731-27-1 N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline Tolylfluanid C10H13Cl2FN2O2S2 CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is identical to the substance Tolylfluanid 211-986-9 731-27-1 N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline Tolylfluanid C10H13Cl2FN2O2S2 CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is identical to the substance Tolylfluanid 211-986-9 731-27-1 N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline Tolylfluanid C10H13Cl2FN2O2S2 CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is identical to the substance Tolylfluanid 211-986-9 731-27-1 N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline Tolylfluanid C10H13Cl2FN2O2S2 CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is identical to the substance Tolylfluanid 211-986-9 731-27-1 N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline Tolylfluanid C10H13Cl2FN2O2S2 CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is identical to the substance Tolylfluanid 211-986-9 731-27-1 N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline Tolylfluanid C10H13Cl2FN2O2S2 CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Saccharomyces cerevisiae (as organism) S211α Not reported yes, concurrent vehicle without Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is identical to the substance Tolylfluanid 211-986-9 731-27-1 N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline Tolylfluanid C10H13Cl2FN2O2S2 CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Saccharomyces cerevisiae (as organism) S138 Not reported yes, concurrent vehicle with Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is identical to the substance Tolylfluanid 211-986-9 731-27-1 N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline Tolylfluanid C10H13Cl2FN2O2S2 CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Saccharomyces cerevisiae (as organism) S211α Not reported yes, concurrent vehicle with Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is identical to the substance Tolylfluanid 211-986-9 731-27-1 N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline Tolylfluanid C10H13Cl2FN2O2S2 CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Saccharomyces cerevisiae (as organism) S138 Not reported yes, concurrent vehicle without Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is identical to the substance Tolylfluanid 211-986-9 731-27-1 N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline Tolylfluanid C10H13Cl2FN2O2S2 CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Positive RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is identical to the substance Tolylfluanid 211-986-9 731-27-1 N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline Tolylfluanid C10H13Cl2FN2O2S2 CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Positive RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is identical to the substance Tolylfluanid 211-986-9 731-27-1 N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline Tolylfluanid C10H13Cl2FN2O2S2 CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Positive no information RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is identical to the substance Tolylfluanid 211-986-9 731-27-1 N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline Tolylfluanid C10H13Cl2FN2O2S2 CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Positive no information RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is identical to the substance Tolylfluanid 211-986-9 731-27-1 N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline Tolylfluanid C10H13Cl2FN2O2S2 CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is identical to the substance Tolylfluanid 211-986-9 731-27-1 N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline Tolylfluanid C10H13Cl2FN2O2S2 CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is identical to the substance Tolylfluanid 211-986-9 731-27-1 N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline Tolylfluanid C10H13Cl2FN2O2S2 CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Ambiguous RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is identical to the substance Tolylfluanid 211-986-9 731-27-1 N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline Tolylfluanid C10H13Cl2FN2O2S2 CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Ambiguous RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is identical to the substance Tolylfluanid 211-986-9 731-27-1 N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline Tolylfluanid C10H13Cl2FN2O2S2 CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is identical to the substance Tolylfluanid 211-986-9 731-27-1 N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline Tolylfluanid C10H13Cl2FN2O2S2 CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 10 Male/Female oral: unspecified 6.0000000000 h yes not applicable Negative no evidence RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is identical to the substance Tolylfluanid 211-986-9 731-27-1 N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline Tolylfluanid C10H13Cl2FN2O2S2 CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Hamster (as animal) Chinese 10 Male/Female oral: unspecified 6.0000000000 h yes not applicable Positive RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is identical to the substance Tolylfluanid 211-986-9 731-27-1 N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline Tolylfluanid C10H13Cl2FN2O2S2 CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Hamster (as animal) Chinese 10 Male/Female oral: unspecified 48.0000000000 h yes not applicable Positive RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is identical to the substance Tolylfluanid 211-986-9 731-27-1 N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline Tolylfluanid C10H13Cl2FN2O2S2 CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Hamster (as animal) Chinese 10 Male/Female oral: unspecified 24.0000000000 h yes not applicable Positive RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is identical to the substance Tolylfluanid 211-986-9 731-27-1 N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline Tolylfluanid C10H13Cl2FN2O2S2 CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Hamster (as animal) Chinese 20 Male/Female oral: unspecified 12.0000000000 h yes not applicable Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is identical to the substance Tolylfluanid 211-986-9 731-27-1 N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline Tolylfluanid C10H13Cl2FN2O2S2 CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) NMRI 20 Male/Female oral: unspecified 24.0000000000 h yes not applicable Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is identical to the substance Tolylfluanid 211-986-9 731-27-1 N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline Tolylfluanid C10H13Cl2FN2O2S2 CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration other in vivo No guideline available Not reported Not applicable Acceptable Hamster (as animal) Not reported 8 Male oral: unspecified 48.0000000000 h yes not applicable Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is identical to the substance Tolylfluanid 211-986-9 731-27-1 N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline Tolylfluanid C10H13Cl2FN2O2S2 CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration mammalian germ cell cytogenetic assay in vivo According to OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test) No Acceptable House mouse (as animal) NMRI 6 Male oral: unspecified 48.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is identical to the substance Tolylfluanid 211-986-9 731-27-1 N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline Tolylfluanid C10H13Cl2FN2O2S2 CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration mammalian germ cell cytogenetic assay in vivo According to OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test) No Acceptable House mouse (as animal) NMRI 6 Male oral: unspecified 6.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is identical to the substance Tolylfluanid 211-986-9 731-27-1 N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline Tolylfluanid C10H13Cl2FN2O2S2 CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration mammalian germ cell cytogenetic assay in vivo According to OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test) No Acceptable House mouse (as animal) NMRI 6 Male oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is identical to the substance Tolylfluanid 211-986-9 731-27-1 N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline Tolylfluanid C10H13Cl2FN2O2S2 CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) Yes Acceptable House mouse (as animal) NMRI 15 Male oral: unspecified 48.0000000000 D no data not applicable Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is identical to the substance Tolylfluanid 211-986-9 731-27-1 N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline Tolylfluanid C10H13Cl2FN2O2S2 CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mouse spot test in vivo According to OECD Guideline 484 (Genetic Toxicology: Mouse Spot Test) No Acceptable House mouse (as animal) C57BL Male/Female oral: gavage 12.0000000000 D yes, concurrent vehicle not applicable Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is identical to the substance Tolylfluanid 211-986-9 731-27-1 N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline Tolylfluanid C10H13Cl2FN2O2S2 CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mouse spot test in vivo According to OECD Guideline 484 (Genetic Toxicology: Mouse Spot Test) No Acceptable House mouse (as animal) C57BL Male/Female oral: gavage 35.0000000000 D yes, concurrent vehicle not applicable Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is identical to the substance Tolylfluanid 211-986-9 731-27-1 N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline Tolylfluanid C10H13Cl2FN2O2S2 CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vivo No guideline followed Not reported Not applicable Acceptable Rat (as animal) Wistar No data oral: feed 12.0000000000 D yes not applicable Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is identical to the substance Tolylfluanid 211-986-9 731-27-1 N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline Tolylfluanid C10H13Cl2FN2O2S2 CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vivo No guideline followed Not reported Not applicable Acceptable Rat (as animal) Wistar No data oral: feed 12.0000000000 D yes not applicable Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is identical to the substance Tolylfluanid 211-986-9 731-27-1 N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline Tolylfluanid C10H13Cl2FN2O2S2 CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vivo No guideline followed Not reported Not applicable Acceptable Rat (as animal) Wistar No data oral: feed 12.0000000000 D yes not applicable Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is a metabolite of the substance 4-Hydroxymethyl-DMST N'-[4-(hydroxymethyl)phenyl]-N,N-dimethylsulfamide Not in list C9H14N2O3S O=S(=O)(Nc1ccc(cc1)CO)N(C)C InChI=1/C9H14N2O3S/c1-11(2)15(13,14)10-9-5-3-8(7-12)4-6-9/h3-6,10,12H,7H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is a metabolite of the substance 4-Hydroxymethyl-DMST N'-[4-(hydroxymethyl)phenyl]-N,N-dimethylsulfamide Not in list C9H14N2O3S O=S(=O)(Nc1ccc(cc1)CO)N(C)C InChI=1/C9H14N2O3S/c1-11(2)15(13,14)10-9-5-3-8(7-12)4-6-9/h3-6,10,12H,7H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is a metabolite of the substance 4-Hydroxymethyl-DMST N'-[4-(hydroxymethyl)phenyl]-N,N-dimethylsulfamide Not in list C9H14N2O3S O=S(=O)(Nc1ccc(cc1)CO)N(C)C InChI=1/C9H14N2O3S/c1-11(2)15(13,14)10-9-5-3-8(7-12)4-6-9/h3-6,10,12H,7H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is a metabolite of the substance 4-Hydroxymethyl-DMST N'-[4-(hydroxymethyl)phenyl]-N,N-dimethylsulfamide Not in list C9H14N2O3S O=S(=O)(Nc1ccc(cc1)CO)N(C)C InChI=1/C9H14N2O3S/c1-11(2)15(13,14)10-9-5-3-8(7-12)4-6-9/h3-6,10,12H,7H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is a metabolite of the substance 4-Hydroxymethyl-DMST N'-[4-(hydroxymethyl)phenyl]-N,N-dimethylsulfamide Not in list C9H14N2O3S O=S(=O)(Nc1ccc(cc1)CO)N(C)C InChI=1/C9H14N2O3S/c1-11(2)15(13,14)10-9-5-3-8(7-12)4-6-9/h3-6,10,12H,7H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is a metabolite of the substance 4-Hydroxymethyl-DMST N'-[4-(hydroxymethyl)phenyl]-N,N-dimethylsulfamide Not in list C9H14N2O3S O=S(=O)(Nc1ccc(cc1)CO)N(C)C InChI=1/C9H14N2O3S/c1-11(2)15(13,14)10-9-5-3-8(7-12)4-6-9/h3-6,10,12H,7H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is a metabolite of the substance 4-Hydroxymethyl-DMST N'-[4-(hydroxymethyl)phenyl]-N,N-dimethylsulfamide Not in list C9H14N2O3S O=S(=O)(Nc1ccc(cc1)CO)N(C)C InChI=1/C9H14N2O3S/c1-11(2)15(13,14)10-9-5-3-8(7-12)4-6-9/h3-6,10,12H,7H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is a metabolite of the substance 4-Hydroxymethyl-DMST N'-[4-(hydroxymethyl)phenyl]-N,N-dimethylsulfamide Not in list C9H14N2O3S O=S(=O)(Nc1ccc(cc1)CO)N(C)C InChI=1/C9H14N2O3S/c1-11(2)15(13,14)10-9-5-3-8(7-12)4-6-9/h3-6,10,12H,7H2,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is a metabolite of the substance 4-Hydroxymethyl-DMST-glucoside N,N-dimethyl-N´-[(4-(ß-D-glucopyranosyl)-methylphenyl]sulfamide Not in list C16H26N2O8S CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2 InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is a metabolite of the substance 4-Hydroxymethyl-DMST-glucoside N,N-dimethyl-N´-[(4-(ß-D-glucopyranosyl)-methylphenyl]sulfamide Not in list C16H26N2O8S CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2 InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is a metabolite of the substance 4-Hydroxymethyl-DMST-glucoside N,N-dimethyl-N´-[(4-(ß-D-glucopyranosyl)-methylphenyl]sulfamide Not in list C16H26N2O8S CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2 InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is a metabolite of the substance 4-Hydroxymethyl-DMST-glucoside N,N-dimethyl-N´-[(4-(ß-D-glucopyranosyl)-methylphenyl]sulfamide Not in list C16H26N2O8S CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2 InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is a metabolite of the substance 4-Hydroxymethyl-DMST-glucoside N,N-dimethyl-N´-[(4-(ß-D-glucopyranosyl)-methylphenyl]sulfamide Not in list C16H26N2O8S CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2 InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is a metabolite of the substance 4-Hydroxymethyl-DMST-glucoside N,N-dimethyl-N´-[(4-(ß-D-glucopyranosyl)-methylphenyl]sulfamide Not in list C16H26N2O8S CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2 InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is a metabolite of the substance 4-Hydroxymethyl-DMST-glucoside N,N-dimethyl-N´-[(4-(ß-D-glucopyranosyl)-methylphenyl]sulfamide Not in list C16H26N2O8S CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2 InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is a metabolite of the substance 4-Hydroxymethyl-DMST-glucoside N,N-dimethyl-N´-[(4-(ß-D-glucopyranosyl)-methylphenyl]sulfamide Not in list C16H26N2O8S CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2 InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is a metabolite of the substance 2-Hydroxyphenyl-DMST-glucoside N,N-dimethyl-N´-[[2-(ß-D-glucopyranosyl)-4-methyl]phenyl]sulfamide Not in list C15H24N2O8S CN(C)S(=O)(=O)Nc2ccc(C)cc2OC1OC(CO)C(O)C(O)C1O InChI=1/C15H24N2O8S/c1-8-4-5-9(16-26(22,23)17(2)3)10(6-8)24-15-14(21)13(20)12(19)11(7-18)25-15/h4-6,11-16,18-21H,7H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is a metabolite of the substance 2-Hydroxyphenyl-DMST-glucoside N,N-dimethyl-N´-[[2-(ß-D-glucopyranosyl)-4-methyl]phenyl]sulfamide Not in list C15H24N2O8S CN(C)S(=O)(=O)Nc2ccc(C)cc2OC1OC(CO)C(O)C(O)C1O InChI=1/C15H24N2O8S/c1-8-4-5-9(16-26(22,23)17(2)3)10(6-8)24-15-14(21)13(20)12(19)11(7-18)25-15/h4-6,11-16,18-21H,7H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is a metabolite of the substance 2-Hydroxyphenyl-DMST-glucoside N,N-dimethyl-N´-[[2-(ß-D-glucopyranosyl)-4-methyl]phenyl]sulfamide Not in list C15H24N2O8S CN(C)S(=O)(=O)Nc2ccc(C)cc2OC1OC(CO)C(O)C(O)C1O InChI=1/C15H24N2O8S/c1-8-4-5-9(16-26(22,23)17(2)3)10(6-8)24-15-14(21)13(20)12(19)11(7-18)25-15/h4-6,11-16,18-21H,7H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is a metabolite of the substance 2-Hydroxyphenyl-DMST-glucoside N,N-dimethyl-N´-[[2-(ß-D-glucopyranosyl)-4-methyl]phenyl]sulfamide Not in list C15H24N2O8S CN(C)S(=O)(=O)Nc2ccc(C)cc2OC1OC(CO)C(O)C(O)C1O InChI=1/C15H24N2O8S/c1-8-4-5-9(16-26(22,23)17(2)3)10(6-8)24-15-14(21)13(20)12(19)11(7-18)25-15/h4-6,11-16,18-21H,7H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is a metabolite of the substance 2-Hydroxyphenyl-DMST-glucoside N,N-dimethyl-N´-[[2-(ß-D-glucopyranosyl)-4-methyl]phenyl]sulfamide Not in list C15H24N2O8S CN(C)S(=O)(=O)Nc2ccc(C)cc2OC1OC(CO)C(O)C(O)C1O InChI=1/C15H24N2O8S/c1-8-4-5-9(16-26(22,23)17(2)3)10(6-8)24-15-14(21)13(20)12(19)11(7-18)25-15/h4-6,11-16,18-21H,7H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is a metabolite of the substance 2-Hydroxyphenyl-DMST-glucoside N,N-dimethyl-N´-[[2-(ß-D-glucopyranosyl)-4-methyl]phenyl]sulfamide Not in list C15H24N2O8S CN(C)S(=O)(=O)Nc2ccc(C)cc2OC1OC(CO)C(O)C(O)C1O InChI=1/C15H24N2O8S/c1-8-4-5-9(16-26(22,23)17(2)3)10(6-8)24-15-14(21)13(20)12(19)11(7-18)25-15/h4-6,11-16,18-21H,7H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is a metabolite of the substance 2-Hydroxyphenyl-DMST-glucoside N,N-dimethyl-N´-[[2-(ß-D-glucopyranosyl)-4-methyl]phenyl]sulfamide Not in list C15H24N2O8S CN(C)S(=O)(=O)Nc2ccc(C)cc2OC1OC(CO)C(O)C(O)C1O InChI=1/C15H24N2O8S/c1-8-4-5-9(16-26(22,23)17(2)3)10(6-8)24-15-14(21)13(20)12(19)11(7-18)25-15/h4-6,11-16,18-21H,7H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is a metabolite of the substance 2-Hydroxyphenyl-DMST-glucoside N,N-dimethyl-N´-[[2-(ß-D-glucopyranosyl)-4-methyl]phenyl]sulfamide Not in list C15H24N2O8S CN(C)S(=O)(=O)Nc2ccc(C)cc2OC1OC(CO)C(O)C(O)C1O InChI=1/C15H24N2O8S/c1-8-4-5-9(16-26(22,23)17(2)3)10(6-8)24-15-14(21)13(20)12(19)11(7-18)25-15/h4-6,11-16,18-21H,7H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is a metabolite of the substance 2-Hydroxyphenyl-DMST N,N-dimethyl-N´-[(2-hydroxy-4-methyl)-phenyl]sulfamide Not in list C9H14N2O3S Oc1cc(C)ccc1NS(=O)(=O)N(C)C InChI=1/C9H14N2O3S/c1-7-4-5-8(9(12)6-7)10-15(13,14)11(2)3/h4-6,10,12H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is a metabolite of the substance 2-Hydroxyphenyl-DMST N,N-dimethyl-N´-[(2-hydroxy-4-methyl)-phenyl]sulfamide Not in list C9H14N2O3S Oc1cc(C)ccc1NS(=O)(=O)N(C)C InChI=1/C9H14N2O3S/c1-7-4-5-8(9(12)6-7)10-15(13,14)11(2)3/h4-6,10,12H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is a metabolite of the substance 2-Hydroxyphenyl-DMST N,N-dimethyl-N´-[(2-hydroxy-4-methyl)-phenyl]sulfamide Not in list C9H14N2O3S Oc1cc(C)ccc1NS(=O)(=O)N(C)C InChI=1/C9H14N2O3S/c1-7-4-5-8(9(12)6-7)10-15(13,14)11(2)3/h4-6,10,12H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is a metabolite of the substance 2-Hydroxyphenyl-DMST N,N-dimethyl-N´-[(2-hydroxy-4-methyl)-phenyl]sulfamide Not in list C9H14N2O3S Oc1cc(C)ccc1NS(=O)(=O)N(C)C InChI=1/C9H14N2O3S/c1-7-4-5-8(9(12)6-7)10-15(13,14)11(2)3/h4-6,10,12H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is a metabolite of the substance 2-Hydroxyphenyl-DMST N,N-dimethyl-N´-[(2-hydroxy-4-methyl)-phenyl]sulfamide Not in list C9H14N2O3S Oc1cc(C)ccc1NS(=O)(=O)N(C)C InChI=1/C9H14N2O3S/c1-7-4-5-8(9(12)6-7)10-15(13,14)11(2)3/h4-6,10,12H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is a metabolite of the substance 2-Hydroxyphenyl-DMST N,N-dimethyl-N´-[(2-hydroxy-4-methyl)-phenyl]sulfamide Not in list C9H14N2O3S Oc1cc(C)ccc1NS(=O)(=O)N(C)C InChI=1/C9H14N2O3S/c1-7-4-5-8(9(12)6-7)10-15(13,14)11(2)3/h4-6,10,12H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is a metabolite of the substance 2-Hydroxyphenyl-DMST N,N-dimethyl-N´-[(2-hydroxy-4-methyl)-phenyl]sulfamide Not in list C9H14N2O3S Oc1cc(C)ccc1NS(=O)(=O)N(C)C InChI=1/C9H14N2O3S/c1-7-4-5-8(9(12)6-7)10-15(13,14)11(2)3/h4-6,10,12H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is a metabolite of the substance 2-Hydroxyphenyl-DMST N,N-dimethyl-N´-[(2-hydroxy-4-methyl)-phenyl]sulfamide Not in list C9H14N2O3S Oc1cc(C)ccc1NS(=O)(=O)N(C)C InChI=1/C9H14N2O3S/c1-7-4-5-8(9(12)6-7)10-15(13,14)11(2)3/h4-6,10,12H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is a metabolite of the substance 2-Hydroxyphenyl-DMST N,N-dimethyl-N´-[(2-hydroxy-4-methyl)-phenyl]sulfamide Not in list C9H14N2O3S Oc1cc(C)ccc1NS(=O)(=O)N(C)C InChI=1/C9H14N2O3S/c1-7-4-5-8(9(12)6-7)10-15(13,14)11(2)3/h4-6,10,12H,1-3H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is a metabolite of the substance 2-Hydroxyphenyl-DMST N,N-dimethyl-N´-[(2-hydroxy-4-methyl)-phenyl]sulfamide Not in list C9H14N2O3S Oc1cc(C)ccc1NS(=O)(=O)N(C)C InChI=1/C9H14N2O3S/c1-7-4-5-8(9(12)6-7)10-15(13,14)11(2)3/h4-6,10,12H,1-3H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Finland Tolylfluanid 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Spiromesifen 283594-90-1 single chemical entity Component is identical to the substance Spiromesifen 283594-90-1 2-oxo-3-(2,4,6-trimethylphenyl)-1-oxaspiro[4.4]non-3-en-4-yl 3,3-dimethylbutanoate Spiromesifen C23H30O4 O=C(CC(C)(C)C)OC1=C(C3=C(C)C=C(C)C=C3C)C(OC21CCCC2)=O InChI=1S/C23H30O4/c1-14-11-15(2)18(16(3)12-14)19-20(26-17(24)13-22(4,5)6)23(27-21(19)25)9-7-8-10-23/h11-12H,7-10,13H2,1-6H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Spiromesifen 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spiromesifen 12Oct2012 2012 doi:10.2903/j.efsa.2012.2879
+Spiromesifen 283594-90-1 single chemical entity Component is identical to the substance Spiromesifen 283594-90-1 2-oxo-3-(2,4,6-trimethylphenyl)-1-oxaspiro[4.4]non-3-en-4-yl 3,3-dimethylbutanoate Spiromesifen C23H30O4 O=C(CC(C)(C)C)OC1=C(C3=C(C)C=C(C)C=C3C)C(OC21CCCC2)=O InChI=1S/C23H30O4/c1-14-11-15(2)18(16(3)12-14)19-20(26-17(24)13-22(4,5)6)23(27-21(19)25)9-7-8-10-23/h11-12H,7-10,13H2,1-6H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Spiromesifen 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spiromesifen 12Oct2012 2012 doi:10.2903/j.efsa.2012.2879
+Spiromesifen 283594-90-1 single chemical entity Component is identical to the substance Spiromesifen 283594-90-1 2-oxo-3-(2,4,6-trimethylphenyl)-1-oxaspiro[4.4]non-3-en-4-yl 3,3-dimethylbutanoate Spiromesifen C23H30O4 O=C(CC(C)(C)C)OC1=C(C3=C(C)C=C(C)C=C3C)C(OC21CCCC2)=O InChI=1S/C23H30O4/c1-14-11-15(2)18(16(3)12-14)19-20(26-17(24)13-22(4,5)6)23(27-21(19)25)9-7-8-10-23/h11-12H,7-10,13H2,1-6H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Spiromesifen 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spiromesifen 12Oct2012 2012 doi:10.2903/j.efsa.2012.2879
+Spiromesifen 283594-90-1 single chemical entity Component is identical to the substance Spiromesifen 283594-90-1 2-oxo-3-(2,4,6-trimethylphenyl)-1-oxaspiro[4.4]non-3-en-4-yl 3,3-dimethylbutanoate Spiromesifen C23H30O4 O=C(CC(C)(C)C)OC1=C(C3=C(C)C=C(C)C=C3C)C(OC21CCCC2)=O InChI=1S/C23H30O4/c1-14-11-15(2)18(16(3)12-14)19-20(26-17(24)13-22(4,5)6)23(27-21(19)25)9-7-8-10-23/h11-12H,7-10,13H2,1-6H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Spiromesifen 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spiromesifen 12Oct2012 2012 doi:10.2903/j.efsa.2012.2879
+Spiromesifen 283594-90-1 single chemical entity Component is identical to the substance Spiromesifen 283594-90-1 2-oxo-3-(2,4,6-trimethylphenyl)-1-oxaspiro[4.4]non-3-en-4-yl 3,3-dimethylbutanoate Spiromesifen C23H30O4 O=C(CC(C)(C)C)OC1=C(C3=C(C)C=C(C)C=C3C)C(OC21CCCC2)=O InChI=1S/C23H30O4/c1-14-11-15(2)18(16(3)12-14)19-20(26-17(24)13-22(4,5)6)23(27-21(19)25)9-7-8-10-23/h11-12H,7-10,13H2,1-6H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Spiromesifen 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spiromesifen 12Oct2012 2012 doi:10.2903/j.efsa.2012.2879
+Spiromesifen 283594-90-1 single chemical entity Component is identical to the substance Spiromesifen 283594-90-1 2-oxo-3-(2,4,6-trimethylphenyl)-1-oxaspiro[4.4]non-3-en-4-yl 3,3-dimethylbutanoate Spiromesifen C23H30O4 O=C(CC(C)(C)C)OC1=C(C3=C(C)C=C(C)C=C3C)C(OC21CCCC2)=O InChI=1S/C23H30O4/c1-14-11-15(2)18(16(3)12-14)19-20(26-17(24)13-22(4,5)6)23(27-21(19)25)9-7-8-10-23/h11-12H,7-10,13H2,1-6H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Spiromesifen 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spiromesifen 12Oct2012 2012 doi:10.2903/j.efsa.2012.2879
+Spiromesifen 283594-90-1 single chemical entity Component is identical to the substance Spiromesifen 283594-90-1 2-oxo-3-(2,4,6-trimethylphenyl)-1-oxaspiro[4.4]non-3-en-4-yl 3,3-dimethylbutanoate Spiromesifen C23H30O4 O=C(CC(C)(C)C)OC1=C(C3=C(C)C=C(C)C=C3C)C(OC21CCCC2)=O InChI=1S/C23H30O4/c1-14-11-15(2)18(16(3)12-14)19-20(26-17(24)13-22(4,5)6)23(27-21(19)25)9-7-8-10-23/h11-12H,7-10,13H2,1-6H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Spiromesifen 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spiromesifen 12Oct2012 2012 doi:10.2903/j.efsa.2012.2879
+Spiromesifen 283594-90-1 single chemical entity Component is identical to the substance Spiromesifen 283594-90-1 2-oxo-3-(2,4,6-trimethylphenyl)-1-oxaspiro[4.4]non-3-en-4-yl 3,3-dimethylbutanoate Spiromesifen C23H30O4 O=C(CC(C)(C)C)OC1=C(C3=C(C)C=C(C)C=C3C)C(OC21CCCC2)=O InChI=1S/C23H30O4/c1-14-11-15(2)18(16(3)12-14)19-20(26-17(24)13-22(4,5)6)23(27-21(19)25)9-7-8-10-23/h11-12H,7-10,13H2,1-6H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Spiromesifen 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spiromesifen 12Oct2012 2012 doi:10.2903/j.efsa.2012.2879
+Spiromesifen 283594-90-1 single chemical entity Component is identical to the substance Spiromesifen 283594-90-1 2-oxo-3-(2,4,6-trimethylphenyl)-1-oxaspiro[4.4]non-3-en-4-yl 3,3-dimethylbutanoate Spiromesifen C23H30O4 O=C(CC(C)(C)C)OC1=C(C3=C(C)C=C(C)C=C3C)C(OC21CCCC2)=O InChI=1S/C23H30O4/c1-14-11-15(2)18(16(3)12-14)19-20(26-17(24)13-22(4,5)6)23(27-21(19)25)9-7-8-10-23/h11-12H,7-10,13H2,1-6H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Spiromesifen 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spiromesifen 12Oct2012 2012 doi:10.2903/j.efsa.2012.2879
+Spiromesifen 283594-90-1 single chemical entity Component is identical to the substance Spiromesifen 283594-90-1 2-oxo-3-(2,4,6-trimethylphenyl)-1-oxaspiro[4.4]non-3-en-4-yl 3,3-dimethylbutanoate Spiromesifen C23H30O4 O=C(CC(C)(C)C)OC1=C(C3=C(C)C=C(C)C=C3C)C(OC21CCCC2)=O InChI=1S/C23H30O4/c1-14-11-15(2)18(16(3)12-14)19-20(26-17(24)13-22(4,5)6)23(27-21(19)25)9-7-8-10-23/h11-12H,7-10,13H2,1-6H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Spiromesifen 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spiromesifen 12Oct2012 2012 doi:10.2903/j.efsa.2012.2879
+Spiromesifen 283594-90-1 single chemical entity Component is identical to the substance Spiromesifen 283594-90-1 2-oxo-3-(2,4,6-trimethylphenyl)-1-oxaspiro[4.4]non-3-en-4-yl 3,3-dimethylbutanoate Spiromesifen C23H30O4 O=C(CC(C)(C)C)OC1=C(C3=C(C)C=C(C)C=C3C)C(OC21CCCC2)=O InChI=1S/C23H30O4/c1-14-11-15(2)18(16(3)12-14)19-20(26-17(24)13-22(4,5)6)23(27-21(19)25)9-7-8-10-23/h11-12H,7-10,13H2,1-6H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Spiromesifen 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spiromesifen 12Oct2012 2012 doi:10.2903/j.efsa.2012.2879
+Spiromesifen 283594-90-1 single chemical entity Component is identical to the substance Spiromesifen 283594-90-1 2-oxo-3-(2,4,6-trimethylphenyl)-1-oxaspiro[4.4]non-3-en-4-yl 3,3-dimethylbutanoate Spiromesifen C23H30O4 O=C(CC(C)(C)C)OC1=C(C3=C(C)C=C(C)C=C3C)C(OC21CCCC2)=O InChI=1S/C23H30O4/c1-14-11-15(2)18(16(3)12-14)19-20(26-17(24)13-22(4,5)6)23(27-21(19)25)9-7-8-10-23/h11-12H,7-10,13H2,1-6H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Spiromesifen 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spiromesifen 12Oct2012 2012 doi:10.2903/j.efsa.2012.2879
+Spiromesifen 283594-90-1 single chemical entity Component is identical to the substance Spiromesifen 283594-90-1 2-oxo-3-(2,4,6-trimethylphenyl)-1-oxaspiro[4.4]non-3-en-4-yl 3,3-dimethylbutanoate Spiromesifen C23H30O4 O=C(CC(C)(C)C)OC1=C(C3=C(C)C=C(C)C=C3C)C(OC21CCCC2)=O InChI=1S/C23H30O4/c1-14-11-15(2)18(16(3)12-14)19-20(26-17(24)13-22(4,5)6)23(27-21(19)25)9-7-8-10-23/h11-12H,7-10,13H2,1-6H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Spiromesifen 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spiromesifen 12Oct2012 2012 doi:10.2903/j.efsa.2012.2879
+Spiromesifen 283594-90-1 single chemical entity Component is identical to the substance Spiromesifen 283594-90-1 2-oxo-3-(2,4,6-trimethylphenyl)-1-oxaspiro[4.4]non-3-en-4-yl 3,3-dimethylbutanoate Spiromesifen C23H30O4 O=C(CC(C)(C)C)OC1=C(C3=C(C)C=C(C)C=C3C)C(OC21CCCC2)=O InChI=1S/C23H30O4/c1-14-11-15(2)18(16(3)12-14)19-20(26-17(24)13-22(4,5)6)23(27-21(19)25)9-7-8-10-23/h11-12H,7-10,13H2,1-6H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Spiromesifen 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spiromesifen 12Oct2012 2012 doi:10.2903/j.efsa.2012.2879
+Spiromesifen 283594-90-1 single chemical entity Component is identical to the substance Spiromesifen 283594-90-1 2-oxo-3-(2,4,6-trimethylphenyl)-1-oxaspiro[4.4]non-3-en-4-yl 3,3-dimethylbutanoate Spiromesifen C23H30O4 O=C(CC(C)(C)C)OC1=C(C3=C(C)C=C(C)C=C3C)C(OC21CCCC2)=O InChI=1S/C23H30O4/c1-14-11-15(2)18(16(3)12-14)19-20(26-17(24)13-22(4,5)6)23(27-21(19)25)9-7-8-10-23/h11-12H,7-10,13H2,1-6H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI Male intraperitoneal 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The United Kingdom Spiromesifen 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spiromesifen 12Oct2012 2012 doi:10.2903/j.efsa.2012.2879
+Spiroxamine 118134-30-8 single chemical entity Component is identical to the substance Spiroxamine 118134-30-8 N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine Spiroxamine (sum of isomers) C18H35NO2 CCCN(CC)CC1COC2(O1)CCC(CC2)C(C)(C)C InChI=1S/C18H35NO2/c1-6-12-19(7-2)13-16-14-20-18(21-16)10-8-15(9-11-18)17(3,4)5/h15-16H,6-14H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany Spiroxamine 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spiroxamine. 22Oct2010 2010 doi:10.2903/j.efsa.2010.1719
+Spiroxamine 118134-30-8 single chemical entity Component is identical to the substance Spiroxamine 118134-30-8 N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine Spiroxamine (sum of isomers) C18H35NO2 CCCN(CC)CC1COC2(O1)CCC(CC2)C(C)(C)C InChI=1S/C18H35NO2/c1-6-12-19(7-2)13-16-14-20-18(21-16)10-8-15(9-11-18)17(3,4)5/h15-16H,6-14H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany Spiroxamine 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spiroxamine. 22Oct2010 2010 doi:10.2903/j.efsa.2010.1719
+Spiroxamine 118134-30-8 single chemical entity Component is identical to the substance Spiroxamine 118134-30-8 N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine Spiroxamine (sum of isomers) C18H35NO2 CCCN(CC)CC1COC2(O1)CCC(CC2)C(C)(C)C InChI=1S/C18H35NO2/c1-6-12-19(7-2)13-16-14-20-18(21-16)10-8-15(9-11-18)17(3,4)5/h15-16H,6-14H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany Spiroxamine 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spiroxamine. 22Oct2010 2010 doi:10.2903/j.efsa.2010.1719
+Spiroxamine 118134-30-8 single chemical entity Component is identical to the substance Spiroxamine 118134-30-8 N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine Spiroxamine (sum of isomers) C18H35NO2 CCCN(CC)CC1COC2(O1)CCC(CC2)C(C)(C)C InChI=1S/C18H35NO2/c1-6-12-19(7-2)13-16-14-20-18(21-16)10-8-15(9-11-18)17(3,4)5/h15-16H,6-14H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany Spiroxamine 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spiroxamine. 22Oct2010 2010 doi:10.2903/j.efsa.2010.1719
+Spiroxamine 118134-30-8 single chemical entity Component is identical to the substance Spiroxamine 118134-30-8 N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine Spiroxamine (sum of isomers) C18H35NO2 CCCN(CC)CC1COC2(O1)CCC(CC2)C(C)(C)C InChI=1S/C18H35NO2/c1-6-12-19(7-2)13-16-14-20-18(21-16)10-8-15(9-11-18)17(3,4)5/h15-16H,6-14H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany Spiroxamine 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spiroxamine. 22Oct2010 2010 doi:10.2903/j.efsa.2010.1719
+Spiroxamine 118134-30-8 single chemical entity Component is identical to the substance Spiroxamine 118134-30-8 N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine Spiroxamine (sum of isomers) C18H35NO2 CCCN(CC)CC1COC2(O1)CCC(CC2)C(C)(C)C InChI=1S/C18H35NO2/c1-6-12-19(7-2)13-16-14-20-18(21-16)10-8-15(9-11-18)17(3,4)5/h15-16H,6-14H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany Spiroxamine 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spiroxamine. 22Oct2010 2010 doi:10.2903/j.efsa.2010.1719
+Spiroxamine 118134-30-8 single chemical entity Component is identical to the substance Spiroxamine 118134-30-8 N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine Spiroxamine (sum of isomers) C18H35NO2 CCCN(CC)CC1COC2(O1)CCC(CC2)C(C)(C)C InChI=1S/C18H35NO2/c1-6-12-19(7-2)13-16-14-20-18(21-16)10-8-15(9-11-18)17(3,4)5/h15-16H,6-14H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany Spiroxamine 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spiroxamine. 22Oct2010 2010 doi:10.2903/j.efsa.2010.1719
+Spiroxamine 118134-30-8 single chemical entity Component is identical to the substance Spiroxamine 118134-30-8 N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine Spiroxamine (sum of isomers) C18H35NO2 CCCN(CC)CC1COC2(O1)CCC(CC2)C(C)(C)C InChI=1S/C18H35NO2/c1-6-12-19(7-2)13-16-14-20-18(21-16)10-8-15(9-11-18)17(3,4)5/h15-16H,6-14H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany Spiroxamine 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spiroxamine. 22Oct2010 2010 doi:10.2903/j.efsa.2010.1719
+Spiroxamine 118134-30-8 single chemical entity Component is identical to the substance Spiroxamine 118134-30-8 N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine Spiroxamine (sum of isomers) C18H35NO2 CCCN(CC)CC1COC2(O1)CCC(CC2)C(C)(C)C InChI=1S/C18H35NO2/c1-6-12-19(7-2)13-16-14-20-18(21-16)10-8-15(9-11-18)17(3,4)5/h15-16H,6-14H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Germany Spiroxamine 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spiroxamine. 22Oct2010 2010 doi:10.2903/j.efsa.2010.1719
+Spiroxamine 118134-30-8 single chemical entity Component is identical to the substance Spiroxamine 118134-30-8 N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine Spiroxamine (sum of isomers) C18H35NO2 CCCN(CC)CC1COC2(O1)CCC(CC2)C(C)(C)C InChI=1S/C18H35NO2/c1-6-12-19(7-2)13-16-14-20-18(21-16)10-8-15(9-11-18)17(3,4)5/h15-16H,6-14H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Germany Spiroxamine 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spiroxamine. 22Oct2010 2010 doi:10.2903/j.efsa.2010.1719
+Spiroxamine 118134-30-8 single chemical entity Component is identical to the substance Spiroxamine 118134-30-8 N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine Spiroxamine (sum of isomers) C18H35NO2 CCCN(CC)CC1COC2(O1)CCC(CC2)C(C)(C)C InChI=1S/C18H35NO2/c1-6-12-19(7-2)13-16-14-20-18(21-16)10-8-15(9-11-18)17(3,4)5/h15-16H,6-14H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Germany Spiroxamine 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spiroxamine. 22Oct2010 2010 doi:10.2903/j.efsa.2010.1719
+Spiroxamine 118134-30-8 single chemical entity Component is identical to the substance Spiroxamine 118134-30-8 N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine Spiroxamine (sum of isomers) C18H35NO2 CCCN(CC)CC1COC2(O1)CCC(CC2)C(C)(C)C InChI=1S/C18H35NO2/c1-6-12-19(7-2)13-16-14-20-18(21-16)10-8-15(9-11-18)17(3,4)5/h15-16H,6-14H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Germany Spiroxamine 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spiroxamine. 22Oct2010 2010 doi:10.2903/j.efsa.2010.1719
+Spiroxamine 118134-30-8 single chemical entity Component is identical to the substance Spiroxamine 118134-30-8 N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine Spiroxamine (sum of isomers) C18H35NO2 CCCN(CC)CC1COC2(O1)CCC(CC2)C(C)(C)C InChI=1S/C18H35NO2/c1-6-12-19(7-2)13-16-14-20-18(21-16)10-8-15(9-11-18)17(3,4)5/h15-16H,6-14H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Germany Spiroxamine 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spiroxamine. 22Oct2010 2010 doi:10.2903/j.efsa.2010.1719
+Spiroxamine 118134-30-8 single chemical entity Component is identical to the substance Spiroxamine 118134-30-8 N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine Spiroxamine (sum of isomers) C18H35NO2 CCCN(CC)CC1COC2(O1)CCC(CC2)C(C)(C)C InChI=1S/C18H35NO2/c1-6-12-19(7-2)13-16-14-20-18(21-16)10-8-15(9-11-18)17(3,4)5/h15-16H,6-14H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle with Negative RMS: Germany Spiroxamine 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spiroxamine. 22Oct2010 2010 doi:10.2903/j.efsa.2010.1719
+Spiroxamine 118134-30-8 single chemical entity Component is identical to the substance Spiroxamine 118134-30-8 N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine Spiroxamine (sum of isomers) C18H35NO2 CCCN(CC)CC1COC2(O1)CCC(CC2)C(C)(C)C InChI=1S/C18H35NO2/c1-6-12-19(7-2)13-16-14-20-18(21-16)10-8-15(9-11-18)17(3,4)5/h15-16H,6-14H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female intraperitoneal 16.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Germany Spiroxamine 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spiroxamine. 22Oct2010 2010 doi:10.2903/j.efsa.2010.1719
+Spiroxamine 118134-30-8 single chemical entity Component is identical to the substance Spiroxamine 118134-30-8 N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine Spiroxamine (sum of isomers) C18H35NO2 CCCN(CC)CC1COC2(O1)CCC(CC2)C(C)(C)C InChI=1S/C18H35NO2/c1-6-12-19(7-2)13-16-14-20-18(21-16)10-8-15(9-11-18)17(3,4)5/h15-16H,6-14H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female intraperitoneal 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Germany Spiroxamine 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spiroxamine. 22Oct2010 2010 doi:10.2903/j.efsa.2010.1719
+Spiroxamine 118134-30-8 single chemical entity Component is identical to the substance Spiroxamine 118134-30-8 N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine Spiroxamine (sum of isomers) C18H35NO2 CCCN(CC)CC1COC2(O1)CCC(CC2)C(C)(C)C InChI=1S/C18H35NO2/c1-6-12-19(7-2)13-16-14-20-18(21-16)10-8-15(9-11-18)17(3,4)5/h15-16H,6-14H2,1-5H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female intraperitoneal 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Germany Spiroxamine 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spiroxamine. 22Oct2010 2010 doi:10.2903/j.efsa.2010.1719
+Spiroxamine 118134-30-8 single chemical entity Component is a metabolite of the substance [(8-tert-butyl-1,4-dioxaspiro[4.5]dec-2-yl)methyl]ethyl(propyl)amine oxide [(8-tert-butyl-1,4-dioxaspiro[4.5]dec-2-yl)methyl]ethyl(propyl)amine oxide Not in list C18H35NO3 CC(C)(C)C1CCC2(CC1)OCC(C[N+]([O-])(CC)CCC)O2 InChI=1/C18H35NO3/c1-6-12-19(20,7-2)13-16-14-21-18(22-16)10-8-15(9-11-18)17(3,4)5/h15-16H,6-14H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany Spiroxamine 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spiroxamine. 22Oct2010 2010 doi:10.2903/j.efsa.2010.1719
+Spiroxamine 118134-30-8 single chemical entity Component is a metabolite of the substance [(8-tert-butyl-1,4-dioxaspiro[4.5]dec-2-yl)methyl]ethyl(propyl)amine oxide [(8-tert-butyl-1,4-dioxaspiro[4.5]dec-2-yl)methyl]ethyl(propyl)amine oxide Not in list C18H35NO3 CC(C)(C)C1CCC2(CC1)OCC(C[N+]([O-])(CC)CCC)O2 InChI=1/C18H35NO3/c1-6-12-19(20,7-2)13-16-14-21-18(22-16)10-8-15(9-11-18)17(3,4)5/h15-16H,6-14H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany Spiroxamine 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spiroxamine. 22Oct2010 2010 doi:10.2903/j.efsa.2010.1719
+Spiroxamine 118134-30-8 single chemical entity Component is a metabolite of the substance [(8-tert-butyl-1,4-dioxaspiro[4.5]dec-2-yl)methyl]ethyl(propyl)amine oxide [(8-tert-butyl-1,4-dioxaspiro[4.5]dec-2-yl)methyl]ethyl(propyl)amine oxide Not in list C18H35NO3 CC(C)(C)C1CCC2(CC1)OCC(C[N+]([O-])(CC)CCC)O2 InChI=1/C18H35NO3/c1-6-12-19(20,7-2)13-16-14-21-18(22-16)10-8-15(9-11-18)17(3,4)5/h15-16H,6-14H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany Spiroxamine 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spiroxamine. 22Oct2010 2010 doi:10.2903/j.efsa.2010.1719
+Spiroxamine 118134-30-8 single chemical entity Component is a metabolite of the substance [(8-tert-butyl-1,4-dioxaspiro[4.5]dec-2-yl)methyl]ethyl(propyl)amine oxide [(8-tert-butyl-1,4-dioxaspiro[4.5]dec-2-yl)methyl]ethyl(propyl)amine oxide Not in list C18H35NO3 CC(C)(C)C1CCC2(CC1)OCC(C[N+]([O-])(CC)CCC)O2 InChI=1/C18H35NO3/c1-6-12-19(20,7-2)13-16-14-21-18(22-16)10-8-15(9-11-18)17(3,4)5/h15-16H,6-14H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany Spiroxamine 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spiroxamine. 22Oct2010 2010 doi:10.2903/j.efsa.2010.1719
+Spiroxamine 118134-30-8 single chemical entity Component is a metabolite of the substance [(8-tert-butyl-1,4-dioxaspiro[4.5]dec-2-yl)methyl]ethyl(propyl)amine oxide [(8-tert-butyl-1,4-dioxaspiro[4.5]dec-2-yl)methyl]ethyl(propyl)amine oxide Not in list C18H35NO3 CC(C)(C)C1CCC2(CC1)OCC(C[N+]([O-])(CC)CCC)O2 InChI=1/C18H35NO3/c1-6-12-19(20,7-2)13-16-14-21-18(22-16)10-8-15(9-11-18)17(3,4)5/h15-16H,6-14H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany Spiroxamine 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spiroxamine. 22Oct2010 2010 doi:10.2903/j.efsa.2010.1719
+Spiroxamine 118134-30-8 single chemical entity Component is a metabolite of the substance [(8-tert-butyl-1,4-dioxaspiro[4.5]dec-2-yl)methyl]ethyl(propyl)amine oxide [(8-tert-butyl-1,4-dioxaspiro[4.5]dec-2-yl)methyl]ethyl(propyl)amine oxide Not in list C18H35NO3 CC(C)(C)C1CCC2(CC1)OCC(C[N+]([O-])(CC)CCC)O2 InChI=1/C18H35NO3/c1-6-12-19(20,7-2)13-16-14-21-18(22-16)10-8-15(9-11-18)17(3,4)5/h15-16H,6-14H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany Spiroxamine 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spiroxamine. 22Oct2010 2010 doi:10.2903/j.efsa.2010.1719
+Spiroxamine 118134-30-8 single chemical entity Component is a metabolite of the substance [(8-tert-butyl-1,4-dioxaspiro[4.5]dec-2-yl)methyl]ethyl(propyl)amine oxide [(8-tert-butyl-1,4-dioxaspiro[4.5]dec-2-yl)methyl]ethyl(propyl)amine oxide Not in list C18H35NO3 CC(C)(C)C1CCC2(CC1)OCC(C[N+]([O-])(CC)CCC)O2 InChI=1/C18H35NO3/c1-6-12-19(20,7-2)13-16-14-21-18(22-16)10-8-15(9-11-18)17(3,4)5/h15-16H,6-14H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany Spiroxamine 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spiroxamine. 22Oct2010 2010 doi:10.2903/j.efsa.2010.1719
+Spiroxamine 118134-30-8 single chemical entity Component is a metabolite of the substance [(8-tert-butyl-1,4-dioxaspiro[4.5]dec-2-yl)methyl]ethyl(propyl)amine oxide [(8-tert-butyl-1,4-dioxaspiro[4.5]dec-2-yl)methyl]ethyl(propyl)amine oxide Not in list C18H35NO3 CC(C)(C)C1CCC2(CC1)OCC(C[N+]([O-])(CC)CCC)O2 InChI=1/C18H35NO3/c1-6-12-19(20,7-2)13-16-14-21-18(22-16)10-8-15(9-11-18)17(3,4)5/h15-16H,6-14H2,1-5H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany Spiroxamine 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spiroxamine. 22Oct2010 2010 doi:10.2903/j.efsa.2010.1719
+Spiroxamine 118134-30-8 single chemical entity Component is a metabolite of the substance [(8-tert-butyl-1,4-dioxaspiro[4.5]dec-2-yl)methyl]ethyl(propyl)amine oxide [(8-tert-butyl-1,4-dioxaspiro[4.5]dec-2-yl)methyl]ethyl(propyl)amine oxide Not in list C18H35NO3 CC(C)(C)C1CCC2(CC1)OCC(C[N+]([O-])(CC)CCC)O2 InChI=1/C18H35NO3/c1-6-12-19(20,7-2)13-16-14-21-18(22-16)10-8-15(9-11-18)17(3,4)5/h15-16H,6-14H2,1-5H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: Germany Spiroxamine 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spiroxamine. 22Oct2010 2010 doi:10.2903/j.efsa.2010.1719
+Spiroxamine 118134-30-8 single chemical entity Component is a metabolite of the substance [(8-tert-butyl-1,4-dioxaspiro[4.5]dec-2-yl)methyl]ethyl(propyl)amine oxide [(8-tert-butyl-1,4-dioxaspiro[4.5]dec-2-yl)methyl]ethyl(propyl)amine oxide Not in list C18H35NO3 CC(C)(C)C1CCC2(CC1)OCC(C[N+]([O-])(CC)CCC)O2 InChI=1/C18H35NO3/c1-6-12-19(20,7-2)13-16-14-21-18(22-16)10-8-15(9-11-18)17(3,4)5/h15-16H,6-14H2,1-5H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: Germany Spiroxamine 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spiroxamine. 22Oct2010 2010 doi:10.2903/j.efsa.2010.1719
+Spiroxamine 118134-30-8 single chemical entity Component is a metabolite of the substance [(8-tert-butyl-1,4-dioxaspiro[4.5]dec-2-yl)methyl]ethyl(propyl)amine oxide [(8-tert-butyl-1,4-dioxaspiro[4.5]dec-2-yl)methyl]ethyl(propyl)amine oxide Not in list C18H35NO3 CC(C)(C)C1CCC2(CC1)OCC(C[N+]([O-])(CC)CCC)O2 InChI=1/C18H35NO3/c1-6-12-19(20,7-2)13-16-14-21-18(22-16)10-8-15(9-11-18)17(3,4)5/h15-16H,6-14H2,1-5H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: Germany Spiroxamine 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spiroxamine. 22Oct2010 2010 doi:10.2903/j.efsa.2010.1719
+Spiroxamine 118134-30-8 single chemical entity Component is a metabolite of the substance [(8-tert-butyl-1,4-dioxaspiro[4.5]dec-2-yl)methyl]ethyl(propyl)amine oxide [(8-tert-butyl-1,4-dioxaspiro[4.5]dec-2-yl)methyl]ethyl(propyl)amine oxide Not in list C18H35NO3 CC(C)(C)C1CCC2(CC1)OCC(C[N+]([O-])(CC)CCC)O2 InChI=1/C18H35NO3/c1-6-12-19(20,7-2)13-16-14-21-18(22-16)10-8-15(9-11-18)17(3,4)5/h15-16H,6-14H2,1-5H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: Germany Spiroxamine 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spiroxamine. 22Oct2010 2010 doi:10.2903/j.efsa.2010.1719
+Fenhexamid 422-530-5 126833-17-8 single chemical entity Component is identical to the substance Fenhexamid 422-530-5 126833-17-8 N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide Fenhexamid C14H17Cl2NO2 CC1(CCCCC1)C(=O)NC2=C(C(=C(C=C2)O)Cl)Cl InChI=1S/C14H17Cl2NO2/c1-14(7-3-2-4-8-14)13(19)17-9-5-6-10(18)12(16)11(9)15/h5-6,18H,2-4,7-8H2,1H3,(H,17,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The United Kingdom Fenhexamid (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenhexamid 07Jul2014 2014 doi:10.2903/j.efsa.2014.3744
+Fenhexamid 422-530-5 126833-17-8 single chemical entity Component is identical to the substance Fenhexamid 422-530-5 126833-17-8 N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide Fenhexamid C14H17Cl2NO2 CC1(CCCCC1)C(=O)NC2=C(C(=C(C=C2)O)Cl)Cl InChI=1S/C14H17Cl2NO2/c1-14(7-3-2-4-8-14)13(19)17-9-5-6-10(18)12(16)11(9)15/h5-6,18H,2-4,7-8H2,1H3,(H,17,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The United Kingdom Fenhexamid (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenhexamid 07Jul2014 2014 doi:10.2903/j.efsa.2014.3744
+Fenhexamid 422-530-5 126833-17-8 single chemical entity Component is identical to the substance Fenhexamid 422-530-5 126833-17-8 N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide Fenhexamid C14H17Cl2NO2 CC1(CCCCC1)C(=O)NC2=C(C(=C(C=C2)O)Cl)Cl InChI=1S/C14H17Cl2NO2/c1-14(7-3-2-4-8-14)13(19)17-9-5-6-10(18)12(16)11(9)15/h5-6,18H,2-4,7-8H2,1H3,(H,17,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The United Kingdom Fenhexamid (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenhexamid 07Jul2014 2014 doi:10.2903/j.efsa.2014.3744
+Fenhexamid 422-530-5 126833-17-8 single chemical entity Component is identical to the substance Fenhexamid 422-530-5 126833-17-8 N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide Fenhexamid C14H17Cl2NO2 CC1(CCCCC1)C(=O)NC2=C(C(=C(C=C2)O)Cl)Cl InChI=1S/C14H17Cl2NO2/c1-14(7-3-2-4-8-14)13(19)17-9-5-6-10(18)12(16)11(9)15/h5-6,18H,2-4,7-8H2,1H3,(H,17,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The United Kingdom Fenhexamid (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenhexamid 07Jul2014 2014 doi:10.2903/j.efsa.2014.3744
+Fenhexamid 422-530-5 126833-17-8 single chemical entity Component is identical to the substance Fenhexamid 422-530-5 126833-17-8 N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide Fenhexamid C14H17Cl2NO2 CC1(CCCCC1)C(=O)NC2=C(C(=C(C=C2)O)Cl)Cl InChI=1S/C14H17Cl2NO2/c1-14(7-3-2-4-8-14)13(19)17-9-5-6-10(18)12(16)11(9)15/h5-6,18H,2-4,7-8H2,1H3,(H,17,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The United Kingdom Fenhexamid (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenhexamid 07Jul2014 2014 doi:10.2903/j.efsa.2014.3744
+Fenhexamid 422-530-5 126833-17-8 single chemical entity Component is identical to the substance Fenhexamid 422-530-5 126833-17-8 N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide Fenhexamid C14H17Cl2NO2 CC1(CCCCC1)C(=O)NC2=C(C(=C(C=C2)O)Cl)Cl InChI=1S/C14H17Cl2NO2/c1-14(7-3-2-4-8-14)13(19)17-9-5-6-10(18)12(16)11(9)15/h5-6,18H,2-4,7-8H2,1H3,(H,17,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The United Kingdom Fenhexamid (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenhexamid 07Jul2014 2014 doi:10.2903/j.efsa.2014.3744
+Fenhexamid 422-530-5 126833-17-8 single chemical entity Component is identical to the substance Fenhexamid 422-530-5 126833-17-8 N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide Fenhexamid C14H17Cl2NO2 CC1(CCCCC1)C(=O)NC2=C(C(=C(C=C2)O)Cl)Cl InChI=1S/C14H17Cl2NO2/c1-14(7-3-2-4-8-14)13(19)17-9-5-6-10(18)12(16)11(9)15/h5-6,18H,2-4,7-8H2,1H3,(H,17,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The United Kingdom Fenhexamid (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenhexamid 07Jul2014 2014 doi:10.2903/j.efsa.2014.3744
+Fenhexamid 422-530-5 126833-17-8 single chemical entity Component is identical to the substance Fenhexamid 422-530-5 126833-17-8 N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide Fenhexamid C14H17Cl2NO2 CC1(CCCCC1)C(=O)NC2=C(C(=C(C=C2)O)Cl)Cl InChI=1S/C14H17Cl2NO2/c1-14(7-3-2-4-8-14)13(19)17-9-5-6-10(18)12(16)11(9)15/h5-6,18H,2-4,7-8H2,1H3,(H,17,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The United Kingdom Fenhexamid (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenhexamid 07Jul2014 2014 doi:10.2903/j.efsa.2014.3744
+Fenhexamid 422-530-5 126833-17-8 single chemical entity Component is identical to the substance Fenhexamid 422-530-5 126833-17-8 N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide Fenhexamid C14H17Cl2NO2 CC1(CCCCC1)C(=O)NC2=C(C(=C(C=C2)O)Cl)Cl InChI=1S/C14H17Cl2NO2/c1-14(7-3-2-4-8-14)13(19)17-9-5-6-10(18)12(16)11(9)15/h5-6,18H,2-4,7-8H2,1H3,(H,17,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: The United Kingdom Fenhexamid (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenhexamid 07Jul2014 2014 doi:10.2903/j.efsa.2014.3744
+Fenhexamid 422-530-5 126833-17-8 single chemical entity Component is identical to the substance Fenhexamid 422-530-5 126833-17-8 N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide Fenhexamid C14H17Cl2NO2 CC1(CCCCC1)C(=O)NC2=C(C(=C(C=C2)O)Cl)Cl InChI=1S/C14H17Cl2NO2/c1-14(7-3-2-4-8-14)13(19)17-9-5-6-10(18)12(16)11(9)15/h5-6,18H,2-4,7-8H2,1H3,(H,17,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The United Kingdom Fenhexamid (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenhexamid 07Jul2014 2014 doi:10.2903/j.efsa.2014.3744
+Fenhexamid 422-530-5 126833-17-8 single chemical entity Component is identical to the substance Fenhexamid 422-530-5 126833-17-8 N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide Fenhexamid C14H17Cl2NO2 CC1(CCCCC1)C(=O)NC2=C(C(=C(C=C2)O)Cl)Cl InChI=1S/C14H17Cl2NO2/c1-14(7-3-2-4-8-14)13(19)17-9-5-6-10(18)12(16)11(9)15/h5-6,18H,2-4,7-8H2,1H3,(H,17,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The United Kingdom Fenhexamid (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenhexamid 07Jul2014 2014 doi:10.2903/j.efsa.2014.3744
+Fenhexamid 422-530-5 126833-17-8 single chemical entity Component is identical to the substance Fenhexamid 422-530-5 126833-17-8 N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide Fenhexamid C14H17Cl2NO2 CC1(CCCCC1)C(=O)NC2=C(C(=C(C=C2)O)Cl)Cl InChI=1S/C14H17Cl2NO2/c1-14(7-3-2-4-8-14)13(19)17-9-5-6-10(18)12(16)11(9)15/h5-6,18H,2-4,7-8H2,1H3,(H,17,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The United Kingdom Fenhexamid (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenhexamid 07Jul2014 2014 doi:10.2903/j.efsa.2014.3744
+Fenhexamid 422-530-5 126833-17-8 single chemical entity Component is identical to the substance Fenhexamid 422-530-5 126833-17-8 N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide Fenhexamid C14H17Cl2NO2 CC1(CCCCC1)C(=O)NC2=C(C(=C(C=C2)O)Cl)Cl InChI=1S/C14H17Cl2NO2/c1-14(7-3-2-4-8-14)13(19)17-9-5-6-10(18)12(16)11(9)15/h5-6,18H,2-4,7-8H2,1H3,(H,17,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The United Kingdom Fenhexamid (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenhexamid 07Jul2014 2014 doi:10.2903/j.efsa.2014.3744
+Fenhexamid 422-530-5 126833-17-8 single chemical entity Component is identical to the substance Fenhexamid 422-530-5 126833-17-8 N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide Fenhexamid C14H17Cl2NO2 CC1(CCCCC1)C(=O)NC2=C(C(=C(C=C2)O)Cl)Cl InChI=1S/C14H17Cl2NO2/c1-14(7-3-2-4-8-14)13(19)17-9-5-6-10(18)12(16)11(9)15/h5-6,18H,2-4,7-8H2,1H3,(H,17,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: The United Kingdom Fenhexamid (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenhexamid 07Jul2014 2014 doi:10.2903/j.efsa.2014.3744
+Fenhexamid 422-530-5 126833-17-8 single chemical entity Component is identical to the substance Fenhexamid 422-530-5 126833-17-8 N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide Fenhexamid C14H17Cl2NO2 CC1(CCCCC1)C(=O)NC2=C(C(=C(C=C2)O)Cl)Cl InChI=1S/C14H17Cl2NO2/c1-14(7-3-2-4-8-14)13(19)17-9-5-6-10(18)12(16)11(9)15/h5-6,18H,2-4,7-8H2,1H3,(H,17,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The United Kingdom Fenhexamid (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenhexamid 07Jul2014 2014 doi:10.2903/j.efsa.2014.3744
+Fenhexamid 422-530-5 126833-17-8 single chemical entity Component is identical to the substance Fenhexamid 422-530-5 126833-17-8 N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide Fenhexamid C14H17Cl2NO2 CC1(CCCCC1)C(=O)NC2=C(C(=C(C=C2)O)Cl)Cl InChI=1S/C14H17Cl2NO2/c1-14(7-3-2-4-8-14)13(19)17-9-5-6-10(18)12(16)11(9)15/h5-6,18H,2-4,7-8H2,1H3,(H,17,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The United Kingdom Fenhexamid (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenhexamid 07Jul2014 2014 doi:10.2903/j.efsa.2014.3744
+Fenhexamid 422-530-5 126833-17-8 single chemical entity Component is identical to the substance Fenhexamid 422-530-5 126833-17-8 N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide Fenhexamid C14H17Cl2NO2 CC1(CCCCC1)C(=O)NC2=C(C(=C(C=C2)O)Cl)Cl InChI=1S/C14H17Cl2NO2/c1-14(7-3-2-4-8-14)13(19)17-9-5-6-10(18)12(16)11(9)15/h5-6,18H,2-4,7-8H2,1H3,(H,17,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The United Kingdom Fenhexamid (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenhexamid 07Jul2014 2014 doi:10.2903/j.efsa.2014.3744
+Fenhexamid 422-530-5 126833-17-8 single chemical entity Component is identical to the substance Fenhexamid 422-530-5 126833-17-8 N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide Fenhexamid C14H17Cl2NO2 CC1(CCCCC1)C(=O)NC2=C(C(=C(C=C2)O)Cl)Cl InChI=1S/C14H17Cl2NO2/c1-14(7-3-2-4-8-14)13(19)17-9-5-6-10(18)12(16)11(9)15/h5-6,18H,2-4,7-8H2,1H3,(H,17,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The United Kingdom Fenhexamid (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenhexamid 07Jul2014 2014 doi:10.2903/j.efsa.2014.3744
+Fenhexamid 422-530-5 126833-17-8 single chemical entity Component is identical to the substance Fenhexamid 422-530-5 126833-17-8 N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide Fenhexamid C14H17Cl2NO2 CC1(CCCCC1)C(=O)NC2=C(C(=C(C=C2)O)Cl)Cl InChI=1S/C14H17Cl2NO2/c1-14(7-3-2-4-8-14)13(19)17-9-5-6-10(18)12(16)11(9)15/h5-6,18H,2-4,7-8H2,1H3,(H,17,19) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes without Negative RMS: The United Kingdom Fenhexamid (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenhexamid 07Jul2014 2014 doi:10.2903/j.efsa.2014.3744
+Fenhexamid 422-530-5 126833-17-8 single chemical entity Component is identical to the substance Fenhexamid 422-530-5 126833-17-8 N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide Fenhexamid C14H17Cl2NO2 CC1(CCCCC1)C(=O)NC2=C(C(=C(C=C2)O)Cl)Cl InChI=1S/C14H17Cl2NO2/c1-14(7-3-2-4-8-14)13(19)17-9-5-6-10(18)12(16)11(9)15/h5-6,18H,2-4,7-8H2,1H3,(H,17,19) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes without Negative RMS: The United Kingdom Fenhexamid (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenhexamid 07Jul2014 2014 doi:10.2903/j.efsa.2014.3744
+Fenhexamid 422-530-5 126833-17-8 single chemical entity Component is identical to the substance Fenhexamid 422-530-5 126833-17-8 N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide Fenhexamid C14H17Cl2NO2 CC1(CCCCC1)C(=O)NC2=C(C(=C(C=C2)O)Cl)Cl InChI=1S/C14H17Cl2NO2/c1-14(7-3-2-4-8-14)13(19)17-9-5-6-10(18)12(16)11(9)15/h5-6,18H,2-4,7-8H2,1H3,(H,17,19) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes with Negative RMS: The United Kingdom Fenhexamid (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenhexamid 07Jul2014 2014 doi:10.2903/j.efsa.2014.3744
+Fenhexamid 422-530-5 126833-17-8 single chemical entity Component is identical to the substance Fenhexamid 422-530-5 126833-17-8 N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide Fenhexamid C14H17Cl2NO2 CC1(CCCCC1)C(=O)NC2=C(C(=C(C=C2)O)Cl)Cl InChI=1S/C14H17Cl2NO2/c1-14(7-3-2-4-8-14)13(19)17-9-5-6-10(18)12(16)11(9)15/h5-6,18H,2-4,7-8H2,1H3,(H,17,19) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes with Negative RMS: The United Kingdom Fenhexamid (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenhexamid 07Jul2014 2014 doi:10.2903/j.efsa.2014.3744
+Fenhexamid 422-530-5 126833-17-8 single chemical entity Component is identical to the substance Fenhexamid 422-530-5 126833-17-8 N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide Fenhexamid C14H17Cl2NO2 CC1(CCCCC1)C(=O)NC2=C(C(=C(C=C2)O)Cl)Cl InChI=1S/C14H17Cl2NO2/c1-14(7-3-2-4-8-14)13(19)17-9-5-6-10(18)12(16)11(9)15/h5-6,18H,2-4,7-8H2,1H3,(H,17,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Negative RMS: The United Kingdom Fenhexamid (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenhexamid 07Jul2014 2014 doi:10.2903/j.efsa.2014.3744
+Fenhexamid 422-530-5 126833-17-8 single chemical entity Component is identical to the substance Fenhexamid 422-530-5 126833-17-8 N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide Fenhexamid C14H17Cl2NO2 CC1(CCCCC1)C(=O)NC2=C(C(=C(C=C2)O)Cl)Cl InChI=1S/C14H17Cl2NO2/c1-14(7-3-2-4-8-14)13(19)17-9-5-6-10(18)12(16)11(9)15/h5-6,18H,2-4,7-8H2,1H3,(H,17,19) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: The United Kingdom Fenhexamid (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenhexamid 07Jul2014 2014 doi:10.2903/j.efsa.2014.3744
+Fenhexamid 422-530-5 126833-17-8 single chemical entity Component is identical to the substance Fenhexamid 422-530-5 126833-17-8 N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide Fenhexamid C14H17Cl2NO2 CC1(CCCCC1)C(=O)NC2=C(C(=C(C=C2)O)Cl)Cl InChI=1S/C14H17Cl2NO2/c1-14(7-3-2-4-8-14)13(19)17-9-5-6-10(18)12(16)11(9)15/h5-6,18H,2-4,7-8H2,1H3,(H,17,19) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: The United Kingdom Fenhexamid (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenhexamid 07Jul2014 2014 doi:10.2903/j.efsa.2014.3744
+Fenhexamid 422-530-5 126833-17-8 single chemical entity Component is identical to the substance Fenhexamid 422-530-5 126833-17-8 N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide Fenhexamid C14H17Cl2NO2 CC1(CCCCC1)C(=O)NC2=C(C(=C(C=C2)O)Cl)Cl InChI=1S/C14H17Cl2NO2/c1-14(7-3-2-4-8-14)13(19)17-9-5-6-10(18)12(16)11(9)15/h5-6,18H,2-4,7-8H2,1H3,(H,17,19) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: The United Kingdom Fenhexamid (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenhexamid 07Jul2014 2014 doi:10.2903/j.efsa.2014.3744
+Fenhexamid 422-530-5 126833-17-8 single chemical entity Component is identical to the substance Fenhexamid 422-530-5 126833-17-8 N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide Fenhexamid C14H17Cl2NO2 CC1(CCCCC1)C(=O)NC2=C(C(=C(C=C2)O)Cl)Cl InChI=1S/C14H17Cl2NO2/c1-14(7-3-2-4-8-14)13(19)17-9-5-6-10(18)12(16)11(9)15/h5-6,18H,2-4,7-8H2,1H3,(H,17,19) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fenhexamid (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenhexamid 07Jul2014 2014 doi:10.2903/j.efsa.2014.3744
+Fenhexamid 422-530-5 126833-17-8 single chemical entity Component is identical to the substance Fenhexamid 422-530-5 126833-17-8 N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide Fenhexamid C14H17Cl2NO2 CC1(CCCCC1)C(=O)NC2=C(C(=C(C=C2)O)Cl)Cl InChI=1S/C14H17Cl2NO2/c1-14(7-3-2-4-8-14)13(19)17-9-5-6-10(18)12(16)11(9)15/h5-6,18H,2-4,7-8H2,1H3,(H,17,19) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 5 Male/Female intraperitoneal 16.0000000000 h yes not applicable Negative direct evidence-cytotoxicity RMS: The United Kingdom Fenhexamid (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenhexamid 07Jul2014 2014 doi:10.2903/j.efsa.2014.3744
+Fenhexamid 422-530-5 126833-17-8 single chemical entity Component is identical to the substance Fenhexamid 422-530-5 126833-17-8 N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide Fenhexamid C14H17Cl2NO2 CC1(CCCCC1)C(=O)NC2=C(C(=C(C=C2)O)Cl)Cl InChI=1S/C14H17Cl2NO2/c1-14(7-3-2-4-8-14)13(19)17-9-5-6-10(18)12(16)11(9)15/h5-6,18H,2-4,7-8H2,1H3,(H,17,19) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 5 Male/Female intraperitoneal 24.0000000000 h yes not applicable Negative direct evidence-cytotoxicity RMS: The United Kingdom Fenhexamid (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenhexamid 07Jul2014 2014 doi:10.2903/j.efsa.2014.3744
+Fenhexamid 422-530-5 126833-17-8 single chemical entity Component is identical to the substance Fenhexamid 422-530-5 126833-17-8 N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide Fenhexamid C14H17Cl2NO2 CC1(CCCCC1)C(=O)NC2=C(C(=C(C=C2)O)Cl)Cl InChI=1S/C14H17Cl2NO2/c1-14(7-3-2-4-8-14)13(19)17-9-5-6-10(18)12(16)11(9)15/h5-6,18H,2-4,7-8H2,1H3,(H,17,19) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 5 Male/Female intraperitoneal 48.0000000000 h yes not applicable Negative direct evidence-cytotoxicity RMS: The United Kingdom Fenhexamid (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenhexamid 07Jul2014 2014 doi:10.2903/j.efsa.2014.3744
+Spirotetramat 203313-25-1 single chemical entity Component is identical to the substance Spirotetramat 203313-25-1 [3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl] ethyl carbonate Not in list C21H27NO5 CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3=C(C=CC(=C3)C)C InChI=1S/C21H27NO5/c1-5-26-20(24)27-18-17(16-12-13(2)6-7-14(16)3)19(23)22-21(18)10-8-15(25-4)9-11-21/h6-7,12,15H,5,8-11H2,1-4H3,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is identical to the substance Spirotetramat 203313-25-1 [3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl] ethyl carbonate Not in list C21H27NO5 CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3=C(C=CC(=C3)C)C InChI=1S/C21H27NO5/c1-5-26-20(24)27-18-17(16-12-13(2)6-7-14(16)3)19(23)22-21(18)10-8-15(25-4)9-11-21/h6-7,12,15H,5,8-11H2,1-4H3,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is identical to the substance Spirotetramat 203313-25-1 [3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl] ethyl carbonate Not in list C21H27NO5 CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3=C(C=CC(=C3)C)C InChI=1S/C21H27NO5/c1-5-26-20(24)27-18-17(16-12-13(2)6-7-14(16)3)19(23)22-21(18)10-8-15(25-4)9-11-21/h6-7,12,15H,5,8-11H2,1-4H3,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is identical to the substance Spirotetramat 203313-25-1 [3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl] ethyl carbonate Not in list C21H27NO5 CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3=C(C=CC(=C3)C)C InChI=1S/C21H27NO5/c1-5-26-20(24)27-18-17(16-12-13(2)6-7-14(16)3)19(23)22-21(18)10-8-15(25-4)9-11-21/h6-7,12,15H,5,8-11H2,1-4H3,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is identical to the substance Spirotetramat 203313-25-1 [3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl] ethyl carbonate Not in list C21H27NO5 CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3=C(C=CC(=C3)C)C InChI=1S/C21H27NO5/c1-5-26-20(24)27-18-17(16-12-13(2)6-7-14(16)3)19(23)22-21(18)10-8-15(25-4)9-11-21/h6-7,12,15H,5,8-11H2,1-4H3,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is identical to the substance Spirotetramat 203313-25-1 [3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl] ethyl carbonate Not in list C21H27NO5 CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3=C(C=CC(=C3)C)C InChI=1S/C21H27NO5/c1-5-26-20(24)27-18-17(16-12-13(2)6-7-14(16)3)19(23)22-21(18)10-8-15(25-4)9-11-21/h6-7,12,15H,5,8-11H2,1-4H3,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is identical to the substance Spirotetramat 203313-25-1 [3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl] ethyl carbonate Not in list C21H27NO5 CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3=C(C=CC(=C3)C)C InChI=1S/C21H27NO5/c1-5-26-20(24)27-18-17(16-12-13(2)6-7-14(16)3)19(23)22-21(18)10-8-15(25-4)9-11-21/h6-7,12,15H,5,8-11H2,1-4H3,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is identical to the substance Spirotetramat 203313-25-1 [3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl] ethyl carbonate Not in list C21H27NO5 CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3=C(C=CC(=C3)C)C InChI=1S/C21H27NO5/c1-5-26-20(24)27-18-17(16-12-13(2)6-7-14(16)3)19(23)22-21(18)10-8-15(25-4)9-11-21/h6-7,12,15H,5,8-11H2,1-4H3,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is identical to the substance Spirotetramat 203313-25-1 [3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl] ethyl carbonate Not in list C21H27NO5 CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3=C(C=CC(=C3)C)C InChI=1S/C21H27NO5/c1-5-26-20(24)27-18-17(16-12-13(2)6-7-14(16)3)19(23)22-21(18)10-8-15(25-4)9-11-21/h6-7,12,15H,5,8-11H2,1-4H3,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is identical to the substance Spirotetramat 203313-25-1 [3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl] ethyl carbonate Not in list C21H27NO5 CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3=C(C=CC(=C3)C)C InChI=1S/C21H27NO5/c1-5-26-20(24)27-18-17(16-12-13(2)6-7-14(16)3)19(23)22-21(18)10-8-15(25-4)9-11-21/h6-7,12,15H,5,8-11H2,1-4H3,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is identical to the substance Spirotetramat 203313-25-1 [3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl] ethyl carbonate Not in list C21H27NO5 CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3=C(C=CC(=C3)C)C InChI=1S/C21H27NO5/c1-5-26-20(24)27-18-17(16-12-13(2)6-7-14(16)3)19(23)22-21(18)10-8-15(25-4)9-11-21/h6-7,12,15H,5,8-11H2,1-4H3,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is identical to the substance Spirotetramat 203313-25-1 [3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl] ethyl carbonate Not in list C21H27NO5 CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3=C(C=CC(=C3)C)C InChI=1S/C21H27NO5/c1-5-26-20(24)27-18-17(16-12-13(2)6-7-14(16)3)19(23)22-21(18)10-8-15(25-4)9-11-21/h6-7,12,15H,5,8-11H2,1-4H3,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is identical to the substance Spirotetramat 203313-25-1 [3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl] ethyl carbonate Not in list C21H27NO5 CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3=C(C=CC(=C3)C)C InChI=1S/C21H27NO5/c1-5-26-20(24)27-18-17(16-12-13(2)6-7-14(16)3)19(23)22-21(18)10-8-15(25-4)9-11-21/h6-7,12,15H,5,8-11H2,1-4H3,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is identical to the substance Spirotetramat 203313-25-1 [3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl] ethyl carbonate Not in list C21H27NO5 CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3=C(C=CC(=C3)C)C InChI=1S/C21H27NO5/c1-5-26-20(24)27-18-17(16-12-13(2)6-7-14(16)3)19(23)22-21(18)10-8-15(25-4)9-11-21/h6-7,12,15H,5,8-11H2,1-4H3,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is identical to the substance Spirotetramat 203313-25-1 [3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl] ethyl carbonate Not in list C21H27NO5 CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3=C(C=CC(=C3)C)C InChI=1S/C21H27NO5/c1-5-26-20(24)27-18-17(16-12-13(2)6-7-14(16)3)19(23)22-21(18)10-8-15(25-4)9-11-21/h6-7,12,15H,5,8-11H2,1-4H3,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is identical to the substance Spirotetramat 203313-25-1 [3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl] ethyl carbonate Not in list C21H27NO5 CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3=C(C=CC(=C3)C)C InChI=1S/C21H27NO5/c1-5-26-20(24)27-18-17(16-12-13(2)6-7-14(16)3)19(23)22-21(18)10-8-15(25-4)9-11-21/h6-7,12,15H,5,8-11H2,1-4H3,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is identical to the substance Spirotetramat 203313-25-1 [3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl] ethyl carbonate Not in list C21H27NO5 CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3=C(C=CC(=C3)C)C InChI=1S/C21H27NO5/c1-5-26-20(24)27-18-17(16-12-13(2)6-7-14(16)3)19(23)22-21(18)10-8-15(25-4)9-11-21/h6-7,12,15H,5,8-11H2,1-4H3,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is identical to the substance Spirotetramat 203313-25-1 [3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl] ethyl carbonate Not in list C21H27NO5 CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3=C(C=CC(=C3)C)C InChI=1S/C21H27NO5/c1-5-26-20(24)27-18-17(16-12-13(2)6-7-14(16)3)19(23)22-21(18)10-8-15(25-4)9-11-21/h6-7,12,15H,5,8-11H2,1-4H3,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is identical to the substance Spirotetramat 203313-25-1 [3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl] ethyl carbonate Not in list C21H27NO5 CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3=C(C=CC(=C3)C)C InChI=1S/C21H27NO5/c1-5-26-20(24)27-18-17(16-12-13(2)6-7-14(16)3)19(23)22-21(18)10-8-15(25-4)9-11-21/h6-7,12,15H,5,8-11H2,1-4H3,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is identical to the substance Spirotetramat 203313-25-1 [3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl] ethyl carbonate Not in list C21H27NO5 CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3=C(C=CC(=C3)C)C InChI=1S/C21H27NO5/c1-5-26-20(24)27-18-17(16-12-13(2)6-7-14(16)3)19(23)22-21(18)10-8-15(25-4)9-11-21/h6-7,12,15H,5,8-11H2,1-4H3,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is identical to the substance Spirotetramat 203313-25-1 [3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl] ethyl carbonate Not in list C21H27NO5 CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3=C(C=CC(=C3)C)C InChI=1S/C21H27NO5/c1-5-26-20(24)27-18-17(16-12-13(2)6-7-14(16)3)19(23)22-21(18)10-8-15(25-4)9-11-21/h6-7,12,15H,5,8-11H2,1-4H3,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Positive RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is identical to the substance Spirotetramat 203313-25-1 [3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl] ethyl carbonate Not in list C21H27NO5 CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3=C(C=CC(=C3)C)C InChI=1S/C21H27NO5/c1-5-26-20(24)27-18-17(16-12-13(2)6-7-14(16)3)19(23)22-21(18)10-8-15(25-4)9-11-21/h6-7,12,15H,5,8-11H2,1-4H3,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Positive RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is identical to the substance Spirotetramat 203313-25-1 [3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl] ethyl carbonate Not in list C21H27NO5 CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3=C(C=CC(=C3)C)C InChI=1S/C21H27NO5/c1-5-26-20(24)27-18-17(16-12-13(2)6-7-14(16)3)19(23)22-21(18)10-8-15(25-4)9-11-21/h6-7,12,15H,5,8-11H2,1-4H3,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is identical to the substance Spirotetramat 203313-25-1 [3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl] ethyl carbonate Not in list C21H27NO5 CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3=C(C=CC(=C3)C)C InChI=1S/C21H27NO5/c1-5-26-20(24)27-18-17(16-12-13(2)6-7-14(16)3)19(23)22-21(18)10-8-15(25-4)9-11-21/h6-7,12,15H,5,8-11H2,1-4H3,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is identical to the substance Spirotetramat 203313-25-1 [3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl] ethyl carbonate Not in list C21H27NO5 CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3=C(C=CC(=C3)C)C InChI=1S/C21H27NO5/c1-5-26-20(24)27-18-17(16-12-13(2)6-7-14(16)3)19(23)22-21(18)10-8-15(25-4)9-11-21/h6-7,12,15H,5,8-11H2,1-4H3,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 5 Male intraperitoneal 24.0000000000 h yes not applicable Negative direct evidence-cytotoxicity RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is identical to the substance Spirotetramat 203313-25-1 [3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl] ethyl carbonate Not in list C21H27NO5 CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3=C(C=CC(=C3)C)C InChI=1S/C21H27NO5/c1-5-26-20(24)27-18-17(16-12-13(2)6-7-14(16)3)19(23)22-21(18)10-8-15(25-4)9-11-21/h6-7,12,15H,5,8-11H2,1-4H3,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable House mouse (as animal) NMRI 6 Male intraperitoneal 48.0000000000 h yes not applicable Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is identical to the substance Spirotetramat 203313-25-1 [3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl] ethyl carbonate Not in list C21H27NO5 CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3=C(C=CC(=C3)C)C InChI=1S/C21H27NO5/c1-5-26-20(24)27-18-17(16-12-13(2)6-7-14(16)3)19(23)22-21(18)10-8-15(25-4)9-11-21/h6-7,12,15H,5,8-11H2,1-4H3,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable House mouse (as animal) NMRI 6 Male intraperitoneal 24.0000000000 h yes not applicable Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is identical to the substance Spirotetramat 203313-25-1 [3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl] ethyl carbonate Not in list C21H27NO5 CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3=C(C=CC(=C3)C)C InChI=1S/C21H27NO5/c1-5-26-20(24)27-18-17(16-12-13(2)6-7-14(16)3)19(23)22-21(18)10-8-15(25-4)9-11-21/h6-7,12,15H,5,8-11H2,1-4H3,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Wistar 4 Male oral: unspecified 4.0000000000 h no not applicable Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is identical to the substance Spirotetramat 203313-25-1 [3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl] ethyl carbonate Not in list C21H27NO5 CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3=C(C=CC(=C3)C)C InChI=1S/C21H27NO5/c1-5-26-20(24)27-18-17(16-12-13(2)6-7-14(16)3)19(23)22-21(18)10-8-15(25-4)9-11-21/h6-7,12,15H,5,8-11H2,1-4H3,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Wistar 4 Male oral: unspecified 16.0000000000 h no not applicable Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is a metabolite of the substance (5s,8s)-3-(2,5-dimethylphenyl)-3-hydroxy-8-methoxy-1-azaspiro[4.5]decane-2,4-dione 3-(2,5-dimethylphenyl)-3-hydroxy-8-methoxy-1-azaspiro[4.5]decane-2,4-dione Not in list C18H23NO4 Cc1cc(c(C)cc1)C3(O)C(=O)C2(CCC(CC2)OC)NC3=O InChI=1/C18H23NO4/c1-11-4-5-12(2)14(10-11)18(22)15(20)17(19-16(18)21)8-6-13(23-3)7-9-17/h4-5,10,13,22H,6-9H2,1-3H3,(H,19,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is a metabolite of the substance (5s,8s)-3-(2,5-dimethylphenyl)-3-hydroxy-8-methoxy-1-azaspiro[4.5]decane-2,4-dione 3-(2,5-dimethylphenyl)-3-hydroxy-8-methoxy-1-azaspiro[4.5]decane-2,4-dione Not in list C18H23NO4 Cc1cc(c(C)cc1)C3(O)C(=O)C2(CCC(CC2)OC)NC3=O InChI=1/C18H23NO4/c1-11-4-5-12(2)14(10-11)18(22)15(20)17(19-16(18)21)8-6-13(23-3)7-9-17/h4-5,10,13,22H,6-9H2,1-3H3,(H,19,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is a metabolite of the substance (5s,8s)-3-(2,5-dimethylphenyl)-3-hydroxy-8-methoxy-1-azaspiro[4.5]decane-2,4-dione 3-(2,5-dimethylphenyl)-3-hydroxy-8-methoxy-1-azaspiro[4.5]decane-2,4-dione Not in list C18H23NO4 Cc1cc(c(C)cc1)C3(O)C(=O)C2(CCC(CC2)OC)NC3=O InChI=1/C18H23NO4/c1-11-4-5-12(2)14(10-11)18(22)15(20)17(19-16(18)21)8-6-13(23-3)7-9-17/h4-5,10,13,22H,6-9H2,1-3H3,(H,19,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is a metabolite of the substance (5s,8s)-3-(2,5-dimethylphenyl)-3-hydroxy-8-methoxy-1-azaspiro[4.5]decane-2,4-dione 3-(2,5-dimethylphenyl)-3-hydroxy-8-methoxy-1-azaspiro[4.5]decane-2,4-dione Not in list C18H23NO4 Cc1cc(c(C)cc1)C3(O)C(=O)C2(CCC(CC2)OC)NC3=O InChI=1/C18H23NO4/c1-11-4-5-12(2)14(10-11)18(22)15(20)17(19-16(18)21)8-6-13(23-3)7-9-17/h4-5,10,13,22H,6-9H2,1-3H3,(H,19,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is a metabolite of the substance (5s,8s)-3-(2,5-dimethylphenyl)-3-hydroxy-8-methoxy-1-azaspiro[4.5]decane-2,4-dione 3-(2,5-dimethylphenyl)-3-hydroxy-8-methoxy-1-azaspiro[4.5]decane-2,4-dione Not in list C18H23NO4 Cc1cc(c(C)cc1)C3(O)C(=O)C2(CCC(CC2)OC)NC3=O InChI=1/C18H23NO4/c1-11-4-5-12(2)14(10-11)18(22)15(20)17(19-16(18)21)8-6-13(23-3)7-9-17/h4-5,10,13,22H,6-9H2,1-3H3,(H,19,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is a metabolite of the substance (5s,8s)-3-(2,5-dimethylphenyl)-3-hydroxy-8-methoxy-1-azaspiro[4.5]decane-2,4-dione 3-(2,5-dimethylphenyl)-3-hydroxy-8-methoxy-1-azaspiro[4.5]decane-2,4-dione Not in list C18H23NO4 Cc1cc(c(C)cc1)C3(O)C(=O)C2(CCC(CC2)OC)NC3=O InChI=1/C18H23NO4/c1-11-4-5-12(2)14(10-11)18(22)15(20)17(19-16(18)21)8-6-13(23-3)7-9-17/h4-5,10,13,22H,6-9H2,1-3H3,(H,19,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is a metabolite of the substance (5s,8s)-3-(2,5-dimethylphenyl)-3-hydroxy-8-methoxy-1-azaspiro[4.5]decane-2,4-dione 3-(2,5-dimethylphenyl)-3-hydroxy-8-methoxy-1-azaspiro[4.5]decane-2,4-dione Not in list C18H23NO4 Cc1cc(c(C)cc1)C3(O)C(=O)C2(CCC(CC2)OC)NC3=O InChI=1/C18H23NO4/c1-11-4-5-12(2)14(10-11)18(22)15(20)17(19-16(18)21)8-6-13(23-3)7-9-17/h4-5,10,13,22H,6-9H2,1-3H3,(H,19,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is a metabolite of the substance (5s,8s)-3-(2,5-dimethylphenyl)-3-hydroxy-8-methoxy-1-azaspiro[4.5]decane-2,4-dione 3-(2,5-dimethylphenyl)-3-hydroxy-8-methoxy-1-azaspiro[4.5]decane-2,4-dione Not in list C18H23NO4 Cc1cc(c(C)cc1)C3(O)C(=O)C2(CCC(CC2)OC)NC3=O InChI=1/C18H23NO4/c1-11-4-5-12(2)14(10-11)18(22)15(20)17(19-16(18)21)8-6-13(23-3)7-9-17/h4-5,10,13,22H,6-9H2,1-3H3,(H,19,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is a metabolite of the substance (5s,8s)-3-(2,5-dimethylphenyl)-3-hydroxy-8-methoxy-1-azaspiro[4.5]decane-2,4-dione 3-(2,5-dimethylphenyl)-3-hydroxy-8-methoxy-1-azaspiro[4.5]decane-2,4-dione Not in list C18H23NO4 Cc1cc(c(C)cc1)C3(O)C(=O)C2(CCC(CC2)OC)NC3=O InChI=1/C18H23NO4/c1-11-4-5-12(2)14(10-11)18(22)15(20)17(19-16(18)21)8-6-13(23-3)7-9-17/h4-5,10,13,22H,6-9H2,1-3H3,(H,19,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is a metabolite of the substance (5s,8s)-3-(2,5-dimethylphenyl)-3-hydroxy-8-methoxy-1-azaspiro[4.5]decane-2,4-dione 3-(2,5-dimethylphenyl)-3-hydroxy-8-methoxy-1-azaspiro[4.5]decane-2,4-dione Not in list C18H23NO4 Cc1cc(c(C)cc1)C3(O)C(=O)C2(CCC(CC2)OC)NC3=O InChI=1/C18H23NO4/c1-11-4-5-12(2)14(10-11)18(22)15(20)17(19-16(18)21)8-6-13(23-3)7-9-17/h4-5,10,13,22H,6-9H2,1-3H3,(H,19,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is a metabolite of the substance (5s,8s)-3-(2,5-dimethylphenyl)-3,8-dihydroxy-1-azaspiro[4.5]decane-2,4-dione 3-(2,5-dimethylphenyl)-3,8-dihydroxy-1-azaspiro[4.5]decane-2,4-dione Not in list C17H21NO4 Cc1cc(c(C)cc1)C3(O)C(=O)C2(CCC(O)CC2)NC3=O InChI=1/C17H21NO4/c1-10-3-4-11(2)13(9-10)17(22)14(20)16(18-15(17)21)7-5-12(19)6-8-16/h3-4,9,12,19,22H,5-8H2,1-2H3,(H,18,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is a metabolite of the substance (5s,8s)-3-(2,5-dimethylphenyl)-3,8-dihydroxy-1-azaspiro[4.5]decane-2,4-dione 3-(2,5-dimethylphenyl)-3,8-dihydroxy-1-azaspiro[4.5]decane-2,4-dione Not in list C17H21NO4 Cc1cc(c(C)cc1)C3(O)C(=O)C2(CCC(O)CC2)NC3=O InChI=1/C17H21NO4/c1-10-3-4-11(2)13(9-10)17(22)14(20)16(18-15(17)21)7-5-12(19)6-8-16/h3-4,9,12,19,22H,5-8H2,1-2H3,(H,18,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is a metabolite of the substance (5s,8s)-3-(2,5-dimethylphenyl)-3,8-dihydroxy-1-azaspiro[4.5]decane-2,4-dione 3-(2,5-dimethylphenyl)-3,8-dihydroxy-1-azaspiro[4.5]decane-2,4-dione Not in list C17H21NO4 Cc1cc(c(C)cc1)C3(O)C(=O)C2(CCC(O)CC2)NC3=O InChI=1/C17H21NO4/c1-10-3-4-11(2)13(9-10)17(22)14(20)16(18-15(17)21)7-5-12(19)6-8-16/h3-4,9,12,19,22H,5-8H2,1-2H3,(H,18,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is a metabolite of the substance (5s,8s)-3-(2,5-dimethylphenyl)-3,8-dihydroxy-1-azaspiro[4.5]decane-2,4-dione 3-(2,5-dimethylphenyl)-3,8-dihydroxy-1-azaspiro[4.5]decane-2,4-dione Not in list C17H21NO4 Cc1cc(c(C)cc1)C3(O)C(=O)C2(CCC(O)CC2)NC3=O InChI=1/C17H21NO4/c1-10-3-4-11(2)13(9-10)17(22)14(20)16(18-15(17)21)7-5-12(19)6-8-16/h3-4,9,12,19,22H,5-8H2,1-2H3,(H,18,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is a metabolite of the substance (5s,8s)-3-(2,5-dimethylphenyl)-3,8-dihydroxy-1-azaspiro[4.5]decane-2,4-dione 3-(2,5-dimethylphenyl)-3,8-dihydroxy-1-azaspiro[4.5]decane-2,4-dione Not in list C17H21NO4 Cc1cc(c(C)cc1)C3(O)C(=O)C2(CCC(O)CC2)NC3=O InChI=1/C17H21NO4/c1-10-3-4-11(2)13(9-10)17(22)14(20)16(18-15(17)21)7-5-12(19)6-8-16/h3-4,9,12,19,22H,5-8H2,1-2H3,(H,18,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is a metabolite of the substance (5s,8s)-3-(2,5-dimethylphenyl)-3,8-dihydroxy-1-azaspiro[4.5]decane-2,4-dione 3-(2,5-dimethylphenyl)-3,8-dihydroxy-1-azaspiro[4.5]decane-2,4-dione Not in list C17H21NO4 Cc1cc(c(C)cc1)C3(O)C(=O)C2(CCC(O)CC2)NC3=O InChI=1/C17H21NO4/c1-10-3-4-11(2)13(9-10)17(22)14(20)16(18-15(17)21)7-5-12(19)6-8-16/h3-4,9,12,19,22H,5-8H2,1-2H3,(H,18,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is a metabolite of the substance (5s,8s)-3-(2,5-dimethylphenyl)-3,8-dihydroxy-1-azaspiro[4.5]decane-2,4-dione 3-(2,5-dimethylphenyl)-3,8-dihydroxy-1-azaspiro[4.5]decane-2,4-dione Not in list C17H21NO4 Cc1cc(c(C)cc1)C3(O)C(=O)C2(CCC(O)CC2)NC3=O InChI=1/C17H21NO4/c1-10-3-4-11(2)13(9-10)17(22)14(20)16(18-15(17)21)7-5-12(19)6-8-16/h3-4,9,12,19,22H,5-8H2,1-2H3,(H,18,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is a metabolite of the substance (5s,8s)-3-(2,5-dimethylphenyl)-3,8-dihydroxy-1-azaspiro[4.5]decane-2,4-dione 3-(2,5-dimethylphenyl)-3,8-dihydroxy-1-azaspiro[4.5]decane-2,4-dione Not in list C17H21NO4 Cc1cc(c(C)cc1)C3(O)C(=O)C2(CCC(O)CC2)NC3=O InChI=1/C17H21NO4/c1-10-3-4-11(2)13(9-10)17(22)14(20)16(18-15(17)21)7-5-12(19)6-8-16/h3-4,9,12,19,22H,5-8H2,1-2H3,(H,18,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is a metabolite of the substance (5s,8s)-3-(2,5-dimethylphenyl)-3,8-dihydroxy-1-azaspiro[4.5]decane-2,4-dione 3-(2,5-dimethylphenyl)-3,8-dihydroxy-1-azaspiro[4.5]decane-2,4-dione Not in list C17H21NO4 Cc1cc(c(C)cc1)C3(O)C(=O)C2(CCC(O)CC2)NC3=O InChI=1/C17H21NO4/c1-10-3-4-11(2)13(9-10)17(22)14(20)16(18-15(17)21)7-5-12(19)6-8-16/h3-4,9,12,19,22H,5-8H2,1-2H3,(H,18,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is a metabolite of the substance (5s,8s)-3-(2,5-dimethylphenyl)-3,8-dihydroxy-1-azaspiro[4.5]decane-2,4-dione 3-(2,5-dimethylphenyl)-3,8-dihydroxy-1-azaspiro[4.5]decane-2,4-dione Not in list C17H21NO4 Cc1cc(c(C)cc1)C3(O)C(=O)C2(CCC(O)CC2)NC3=O InChI=1/C17H21NO4/c1-10-3-4-11(2)13(9-10)17(22)14(20)16(18-15(17)21)7-5-12(19)6-8-16/h3-4,9,12,19,22H,5-8H2,1-2H3,(H,18,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is a metabolite of the substance (5s,8s)-3-(2,5-dimethylphenyl)-3,4,8-trihydroxy-1-azaspiro[4.5]decan-2-one 3-(2,5-dimethylphenyl)-3,4,8-trihydroxy-1-azaspiro[4.5]decan-2-one Not in list C17H23NO4 Cc1cc(c(C)cc1)C3(O)C(=O)NC2(CCC(O)CC2)C3O InChI=1/C17H23NO4/c1-10-3-4-11(2)13(9-10)17(22)14(20)16(18-15(17)21)7-5-12(19)6-8-16/h3-4,9,12,14,19-20,22H,5-8H2,1-2H3,(H,18,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is a metabolite of the substance (5s,8s)-3-(2,5-dimethylphenyl)-3,4,8-trihydroxy-1-azaspiro[4.5]decan-2-one 3-(2,5-dimethylphenyl)-3,4,8-trihydroxy-1-azaspiro[4.5]decan-2-one Not in list C17H23NO4 Cc1cc(c(C)cc1)C3(O)C(=O)NC2(CCC(O)CC2)C3O InChI=1/C17H23NO4/c1-10-3-4-11(2)13(9-10)17(22)14(20)16(18-15(17)21)7-5-12(19)6-8-16/h3-4,9,12,14,19-20,22H,5-8H2,1-2H3,(H,18,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is a metabolite of the substance (5s,8s)-3-(2,5-dimethylphenyl)-3,4,8-trihydroxy-1-azaspiro[4.5]decan-2-one 3-(2,5-dimethylphenyl)-3,4,8-trihydroxy-1-azaspiro[4.5]decan-2-one Not in list C17H23NO4 Cc1cc(c(C)cc1)C3(O)C(=O)NC2(CCC(O)CC2)C3O InChI=1/C17H23NO4/c1-10-3-4-11(2)13(9-10)17(22)14(20)16(18-15(17)21)7-5-12(19)6-8-16/h3-4,9,12,14,19-20,22H,5-8H2,1-2H3,(H,18,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is a metabolite of the substance (5s,8s)-3-(2,5-dimethylphenyl)-3,4,8-trihydroxy-1-azaspiro[4.5]decan-2-one 3-(2,5-dimethylphenyl)-3,4,8-trihydroxy-1-azaspiro[4.5]decan-2-one Not in list C17H23NO4 Cc1cc(c(C)cc1)C3(O)C(=O)NC2(CCC(O)CC2)C3O InChI=1/C17H23NO4/c1-10-3-4-11(2)13(9-10)17(22)14(20)16(18-15(17)21)7-5-12(19)6-8-16/h3-4,9,12,14,19-20,22H,5-8H2,1-2H3,(H,18,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is a metabolite of the substance (5s,8s)-3-(2,5-dimethylphenyl)-3,4,8-trihydroxy-1-azaspiro[4.5]decan-2-one 3-(2,5-dimethylphenyl)-3,4,8-trihydroxy-1-azaspiro[4.5]decan-2-one Not in list C17H23NO4 Cc1cc(c(C)cc1)C3(O)C(=O)NC2(CCC(O)CC2)C3O InChI=1/C17H23NO4/c1-10-3-4-11(2)13(9-10)17(22)14(20)16(18-15(17)21)7-5-12(19)6-8-16/h3-4,9,12,14,19-20,22H,5-8H2,1-2H3,(H,18,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is a metabolite of the substance (5s,8s)-3-(2,5-dimethylphenyl)-3,4,8-trihydroxy-1-azaspiro[4.5]decan-2-one 3-(2,5-dimethylphenyl)-3,4,8-trihydroxy-1-azaspiro[4.5]decan-2-one Not in list C17H23NO4 Cc1cc(c(C)cc1)C3(O)C(=O)NC2(CCC(O)CC2)C3O InChI=1/C17H23NO4/c1-10-3-4-11(2)13(9-10)17(22)14(20)16(18-15(17)21)7-5-12(19)6-8-16/h3-4,9,12,14,19-20,22H,5-8H2,1-2H3,(H,18,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is a metabolite of the substance (5s,8s)-3-(2,5-dimethylphenyl)-3,4,8-trihydroxy-1-azaspiro[4.5]decan-2-one 3-(2,5-dimethylphenyl)-3,4,8-trihydroxy-1-azaspiro[4.5]decan-2-one Not in list C17H23NO4 Cc1cc(c(C)cc1)C3(O)C(=O)NC2(CCC(O)CC2)C3O InChI=1/C17H23NO4/c1-10-3-4-11(2)13(9-10)17(22)14(20)16(18-15(17)21)7-5-12(19)6-8-16/h3-4,9,12,14,19-20,22H,5-8H2,1-2H3,(H,18,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is a metabolite of the substance (5s,8s)-3-(2,5-dimethylphenyl)-3,4,8-trihydroxy-1-azaspiro[4.5]decan-2-one 3-(2,5-dimethylphenyl)-3,4,8-trihydroxy-1-azaspiro[4.5]decan-2-one Not in list C17H23NO4 Cc1cc(c(C)cc1)C3(O)C(=O)NC2(CCC(O)CC2)C3O InChI=1/C17H23NO4/c1-10-3-4-11(2)13(9-10)17(22)14(20)16(18-15(17)21)7-5-12(19)6-8-16/h3-4,9,12,14,19-20,22H,5-8H2,1-2H3,(H,18,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is a metabolite of the substance (5s,8s)-3-(2,5-dimethylphenyl)-3,4,8-trihydroxy-1-azaspiro[4.5]decan-2-one 3-(2,5-dimethylphenyl)-3,4,8-trihydroxy-1-azaspiro[4.5]decan-2-one Not in list C17H23NO4 Cc1cc(c(C)cc1)C3(O)C(=O)NC2(CCC(O)CC2)C3O InChI=1/C17H23NO4/c1-10-3-4-11(2)13(9-10)17(22)14(20)16(18-15(17)21)7-5-12(19)6-8-16/h3-4,9,12,14,19-20,22H,5-8H2,1-2H3,(H,18,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is a metabolite of the substance (5s,8s)-3-(2,5-dimethylphenyl)-3,4,8-trihydroxy-1-azaspiro[4.5]decan-2-one 3-(2,5-dimethylphenyl)-3,4,8-trihydroxy-1-azaspiro[4.5]decan-2-one Not in list C17H23NO4 Cc1cc(c(C)cc1)C3(O)C(=O)NC2(CCC(O)CC2)C3O InChI=1/C17H23NO4/c1-10-3-4-11(2)13(9-10)17(22)14(20)16(18-15(17)21)7-5-12(19)6-8-16/h3-4,9,12,14,19-20,22H,5-8H2,1-2H3,(H,18,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is a metabolite of the substance (5s,8s)-3-(2,5-dimethylphenyl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]decan-2-one 3-(2,5-dimethylphenyl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]decan-2-one Not in list C18H25NO3 Cc3cc(C2C(=O)NC1(CCC(CC1)OC)C2O)c(C)cc3 InChI=1/C18H25NO3/c1-11-4-5-12(2)14(10-11)15-16(20)18(19-17(15)21)8-6-13(22-3)7-9-18/h4-5,10,13,15-16,20H,6-9H2,1-3H3,(H,19,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is a metabolite of the substance (5s,8s)-3-(2,5-dimethylphenyl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]decan-2-one 3-(2,5-dimethylphenyl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]decan-2-one Not in list C18H25NO3 Cc3cc(C2C(=O)NC1(CCC(CC1)OC)C2O)c(C)cc3 InChI=1/C18H25NO3/c1-11-4-5-12(2)14(10-11)15-16(20)18(19-17(15)21)8-6-13(22-3)7-9-18/h4-5,10,13,15-16,20H,6-9H2,1-3H3,(H,19,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is a metabolite of the substance (5s,8s)-3-(2,5-dimethylphenyl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]decan-2-one 3-(2,5-dimethylphenyl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]decan-2-one Not in list C18H25NO3 Cc3cc(C2C(=O)NC1(CCC(CC1)OC)C2O)c(C)cc3 InChI=1/C18H25NO3/c1-11-4-5-12(2)14(10-11)15-16(20)18(19-17(15)21)8-6-13(22-3)7-9-18/h4-5,10,13,15-16,20H,6-9H2,1-3H3,(H,19,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is a metabolite of the substance (5s,8s)-3-(2,5-dimethylphenyl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]decan-2-one 3-(2,5-dimethylphenyl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]decan-2-one Not in list C18H25NO3 Cc3cc(C2C(=O)NC1(CCC(CC1)OC)C2O)c(C)cc3 InChI=1/C18H25NO3/c1-11-4-5-12(2)14(10-11)15-16(20)18(19-17(15)21)8-6-13(22-3)7-9-18/h4-5,10,13,15-16,20H,6-9H2,1-3H3,(H,19,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is a metabolite of the substance (5s,8s)-3-(2,5-dimethylphenyl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]decan-2-one 3-(2,5-dimethylphenyl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]decan-2-one Not in list C18H25NO3 Cc3cc(C2C(=O)NC1(CCC(CC1)OC)C2O)c(C)cc3 InChI=1/C18H25NO3/c1-11-4-5-12(2)14(10-11)15-16(20)18(19-17(15)21)8-6-13(22-3)7-9-18/h4-5,10,13,15-16,20H,6-9H2,1-3H3,(H,19,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is a metabolite of the substance (5s,8s)-3-(2,5-dimethylphenyl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]decan-2-one 3-(2,5-dimethylphenyl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]decan-2-one Not in list C18H25NO3 Cc3cc(C2C(=O)NC1(CCC(CC1)OC)C2O)c(C)cc3 InChI=1/C18H25NO3/c1-11-4-5-12(2)14(10-11)15-16(20)18(19-17(15)21)8-6-13(22-3)7-9-18/h4-5,10,13,15-16,20H,6-9H2,1-3H3,(H,19,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is a metabolite of the substance (5s,8s)-3-(2,5-dimethylphenyl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]decan-2-one 3-(2,5-dimethylphenyl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]decan-2-one Not in list C18H25NO3 Cc3cc(C2C(=O)NC1(CCC(CC1)OC)C2O)c(C)cc3 InChI=1/C18H25NO3/c1-11-4-5-12(2)14(10-11)15-16(20)18(19-17(15)21)8-6-13(22-3)7-9-18/h4-5,10,13,15-16,20H,6-9H2,1-3H3,(H,19,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is a metabolite of the substance (5s,8s)-3-(2,5-dimethylphenyl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]decan-2-one 3-(2,5-dimethylphenyl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]decan-2-one Not in list C18H25NO3 Cc3cc(C2C(=O)NC1(CCC(CC1)OC)C2O)c(C)cc3 InChI=1/C18H25NO3/c1-11-4-5-12(2)14(10-11)15-16(20)18(19-17(15)21)8-6-13(22-3)7-9-18/h4-5,10,13,15-16,20H,6-9H2,1-3H3,(H,19,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is a metabolite of the substance (5s,8s)-3-(2,5-dimethylphenyl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]decan-2-one 3-(2,5-dimethylphenyl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]decan-2-one Not in list C18H25NO3 Cc3cc(C2C(=O)NC1(CCC(CC1)OC)C2O)c(C)cc3 InChI=1/C18H25NO3/c1-11-4-5-12(2)14(10-11)15-16(20)18(19-17(15)21)8-6-13(22-3)7-9-18/h4-5,10,13,15-16,20H,6-9H2,1-3H3,(H,19,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Spirotetramat 203313-25-1 single chemical entity Component is a metabolite of the substance (5s,8s)-3-(2,5-dimethylphenyl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]decan-2-one 3-(2,5-dimethylphenyl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]decan-2-one Not in list C18H25NO3 Cc3cc(C2C(=O)NC1(CCC(CC1)OC)C2O)c(C)cc3 InChI=1/C18H25NO3/c1-11-4-5-12(2)14(10-11)15-16(20)18(19-17(15)21)8-6-13(22-3)7-9-18/h4-5,10,13,15-16,20H,6-9H2,1-3H3,(H,19,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Austria Spirotetramat 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat. 07Jun2013 2013 doi:10.2903/j.efsa.2013.3243
+Fluazinam 79622-59-6 single chemical entity Component is identical to the substance Fluazinam 79622-59-6 3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine Fluazinam C13H4Cl2F6N4O4 C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle with Negative RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is identical to the substance Fluazinam 79622-59-6 3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine Fluazinam C13H4Cl2F6N4O4 C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is identical to the substance Fluazinam 79622-59-6 3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine Fluazinam C13H4Cl2F6N4O4 C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is identical to the substance Fluazinam 79622-59-6 3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine Fluazinam C13H4Cl2F6N4O4 C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is identical to the substance Fluazinam 79622-59-6 3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine Fluazinam C13H4Cl2F6N4O4 C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is identical to the substance Fluazinam 79622-59-6 3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine Fluazinam C13H4Cl2F6N4O4 C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is identical to the substance Fluazinam 79622-59-6 3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine Fluazinam C13H4Cl2F6N4O4 C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is identical to the substance Fluazinam 79622-59-6 3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine Fluazinam C13H4Cl2F6N4O4 C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is identical to the substance Fluazinam 79622-59-6 3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine Fluazinam C13H4Cl2F6N4O4 C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle without Negative RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is identical to the substance Fluazinam 79622-59-6 3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine Fluazinam C13H4Cl2F6N4O4 C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is identical to the substance Fluazinam 79622-59-6 3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine Fluazinam C13H4Cl2F6N4O4 C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is identical to the substance Fluazinam 79622-59-6 3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine Fluazinam C13H4Cl2F6N4O4 C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is identical to the substance Fluazinam 79622-59-6 3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine Fluazinam C13H4Cl2F6N4O4 C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is identical to the substance Fluazinam 79622-59-6 3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine Fluazinam C13H4Cl2F6N4O4 C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is identical to the substance Fluazinam 79622-59-6 3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine Fluazinam C13H4Cl2F6N4O4 C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is identical to the substance Fluazinam 79622-59-6 3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine Fluazinam C13H4Cl2F6N4O4 C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is identical to the substance Fluazinam 79622-59-6 3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine Fluazinam C13H4Cl2F6N4O4 C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is identical to the substance Fluazinam 79622-59-6 3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine Fluazinam C13H4Cl2F6N4O4 C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is identical to the substance Fluazinam 79622-59-6 3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine Fluazinam C13H4Cl2F6N4O4 C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is identical to the substance Fluazinam 79622-59-6 3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine Fluazinam C13H4Cl2F6N4O4 C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is identical to the substance Fluazinam 79622-59-6 3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine Fluazinam C13H4Cl2F6N4O4 C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is identical to the substance Fluazinam 79622-59-6 3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine Fluazinam C13H4Cl2F6N4O4 C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is identical to the substance Fluazinam 79622-59-6 3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine Fluazinam C13H4Cl2F6N4O4 C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is identical to the substance Fluazinam 79622-59-6 3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine Fluazinam C13H4Cl2F6N4O4 C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is identical to the substance Fluazinam 79622-59-6 3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine Fluazinam C13H4Cl2F6N4O4 C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is identical to the substance Fluazinam 79622-59-6 3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine Fluazinam C13H4Cl2F6N4O4 C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is identical to the substance Fluazinam 79622-59-6 3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine Fluazinam C13H4Cl2F6N4O4 C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is identical to the substance Fluazinam 79622-59-6 3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine Fluazinam C13H4Cl2F6N4O4 C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is identical to the substance Fluazinam 79622-59-6 3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine Fluazinam C13H4Cl2F6N4O4 C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is identical to the substance Fluazinam 79622-59-6 3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine Fluazinam C13H4Cl2F6N4O4 C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is identical to the substance Fluazinam 79622-59-6 3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine Fluazinam C13H4Cl2F6N4O4 C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is identical to the substance Fluazinam 79622-59-6 3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine Fluazinam C13H4Cl2F6N4O4 C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is identical to the substance Fluazinam 79622-59-6 3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine Fluazinam C13H4Cl2F6N4O4 C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is identical to the substance Fluazinam 79622-59-6 3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine Fluazinam C13H4Cl2F6N4O4 C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is identical to the substance Fluazinam 79622-59-6 3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine Fluazinam C13H4Cl2F6N4O4 C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes, concurrent vehicle with Negative RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is identical to the substance Fluazinam 79622-59-6 3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine Fluazinam C13H4Cl2F6N4O4 C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes, concurrent vehicle without Negative RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is identical to the substance Fluazinam 79622-59-6 3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine Fluazinam C13H4Cl2F6N4O4 C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes, concurrent vehicle without Negative RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is identical to the substance Fluazinam 79622-59-6 3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine Fluazinam C13H4Cl2F6N4O4 C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes, concurrent vehicle with Negative RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is identical to the substance Fluazinam 79622-59-6 3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine Fluazinam C13H4Cl2F6N4O4 C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) ICR 10 Male/Female oral: gavage 72.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is identical to the substance Fluazinam 79622-59-6 3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine Fluazinam C13H4Cl2F6N4O4 C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) ICR 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is identical to the substance Fluazinam 79622-59-6 3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine Fluazinam C13H4Cl2F6N4O4 C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) ICR 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is a metabolite of the substance 5-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-4,6-dinitro-o-cresol 3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-2,4-dinitro-6-(trifluoromethyl)phenol Not in list C13H5ClF6N4O5 [O-][N+](=O)c2cc(c(O)c(c2Nc1ncc(cc1Cl)C(F)(F)F)[N+]([O-])=O)C(F)(F)F InChI=1/C13H5ClF6N4O5/c14-6-1-4(12(15,16)17)3-21-11(6)22-8-7(23(26)27)2-5(13(18,19)20)10(25)9(8)24(28)29/h1-3,25H,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is a metabolite of the substance 5-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-4,6-dinitro-o-cresol 3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-2,4-dinitro-6-(trifluoromethyl)phenol Not in list C13H5ClF6N4O5 [O-][N+](=O)c2cc(c(O)c(c2Nc1ncc(cc1Cl)C(F)(F)F)[N+]([O-])=O)C(F)(F)F InChI=1/C13H5ClF6N4O5/c14-6-1-4(12(15,16)17)3-21-11(6)22-8-7(23(26)27)2-5(13(18,19)20)10(25)9(8)24(28)29/h1-3,25H,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is a metabolite of the substance 5-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-4,6-dinitro-o-cresol 3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-2,4-dinitro-6-(trifluoromethyl)phenol Not in list C13H5ClF6N4O5 [O-][N+](=O)c2cc(c(O)c(c2Nc1ncc(cc1Cl)C(F)(F)F)[N+]([O-])=O)C(F)(F)F InChI=1/C13H5ClF6N4O5/c14-6-1-4(12(15,16)17)3-21-11(6)22-8-7(23(26)27)2-5(13(18,19)20)10(25)9(8)24(28)29/h1-3,25H,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Positive RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is a metabolite of the substance 5-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-4,6-dinitro-o-cresol 3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-2,4-dinitro-6-(trifluoromethyl)phenol Not in list C13H5ClF6N4O5 [O-][N+](=O)c2cc(c(O)c(c2Nc1ncc(cc1Cl)C(F)(F)F)[N+]([O-])=O)C(F)(F)F InChI=1/C13H5ClF6N4O5/c14-6-1-4(12(15,16)17)3-21-11(6)22-8-7(23(26)27)2-5(13(18,19)20)10(25)9(8)24(28)29/h1-3,25H,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is a metabolite of the substance 5-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-4,6-dinitro-o-cresol 3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-2,4-dinitro-6-(trifluoromethyl)phenol Not in list C13H5ClF6N4O5 [O-][N+](=O)c2cc(c(O)c(c2Nc1ncc(cc1Cl)C(F)(F)F)[N+]([O-])=O)C(F)(F)F InChI=1/C13H5ClF6N4O5/c14-6-1-4(12(15,16)17)3-21-11(6)22-8-7(23(26)27)2-5(13(18,19)20)10(25)9(8)24(28)29/h1-3,25H,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is a metabolite of the substance 5-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-4,6-dinitro-o-cresol 3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-2,4-dinitro-6-(trifluoromethyl)phenol Not in list C13H5ClF6N4O5 [O-][N+](=O)c2cc(c(O)c(c2Nc1ncc(cc1Cl)C(F)(F)F)[N+]([O-])=O)C(F)(F)F InChI=1/C13H5ClF6N4O5/c14-6-1-4(12(15,16)17)3-21-11(6)22-8-7(23(26)27)2-5(13(18,19)20)10(25)9(8)24(28)29/h1-3,25H,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is a metabolite of the substance 5-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-4,6-dinitro-o-cresol 3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-2,4-dinitro-6-(trifluoromethyl)phenol Not in list C13H5ClF6N4O5 [O-][N+](=O)c2cc(c(O)c(c2Nc1ncc(cc1Cl)C(F)(F)F)[N+]([O-])=O)C(F)(F)F InChI=1/C13H5ClF6N4O5/c14-6-1-4(12(15,16)17)3-21-11(6)22-8-7(23(26)27)2-5(13(18,19)20)10(25)9(8)24(28)29/h1-3,25H,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is a metabolite of the substance 5-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-4,6-dinitro-o-cresol 3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-2,4-dinitro-6-(trifluoromethyl)phenol Not in list C13H5ClF6N4O5 [O-][N+](=O)c2cc(c(O)c(c2Nc1ncc(cc1Cl)C(F)(F)F)[N+]([O-])=O)C(F)(F)F InChI=1/C13H5ClF6N4O5/c14-6-1-4(12(15,16)17)3-21-11(6)22-8-7(23(26)27)2-5(13(18,19)20)10(25)9(8)24(28)29/h1-3,25H,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is a metabolite of the substance 5-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-4,6-dinitro-o-cresol 3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-2,4-dinitro-6-(trifluoromethyl)phenol Not in list C13H5ClF6N4O5 [O-][N+](=O)c2cc(c(O)c(c2Nc1ncc(cc1Cl)C(F)(F)F)[N+]([O-])=O)C(F)(F)F InChI=1/C13H5ClF6N4O5/c14-6-1-4(12(15,16)17)3-21-11(6)22-8-7(23(26)27)2-5(13(18,19)20)10(25)9(8)24(28)29/h1-3,25H,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is a metabolite of the substance 5-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-4,6-dinitro-o-cresol 3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-2,4-dinitro-6-(trifluoromethyl)phenol Not in list C13H5ClF6N4O5 [O-][N+](=O)c2cc(c(O)c(c2Nc1ncc(cc1Cl)C(F)(F)F)[N+]([O-])=O)C(F)(F)F InChI=1/C13H5ClF6N4O5/c14-6-1-4(12(15,16)17)3-21-11(6)22-8-7(23(26)27)2-5(13(18,19)20)10(25)9(8)24(28)29/h1-3,25H,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is a metabolite of the substance 5-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-4,6-dinitro-o-cresol 3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-2,4-dinitro-6-(trifluoromethyl)phenol Not in list C13H5ClF6N4O5 [O-][N+](=O)c2cc(c(O)c(c2Nc1ncc(cc1Cl)C(F)(F)F)[N+]([O-])=O)C(F)(F)F InChI=1/C13H5ClF6N4O5/c14-6-1-4(12(15,16)17)3-21-11(6)22-8-7(23(26)27)2-5(13(18,19)20)10(25)9(8)24(28)29/h1-3,25H,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is a metabolite of the substance 5-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-4,6-dinitro-o-cresol 3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-2,4-dinitro-6-(trifluoromethyl)phenol Not in list C13H5ClF6N4O5 [O-][N+](=O)c2cc(c(O)c(c2Nc1ncc(cc1Cl)C(F)(F)F)[N+]([O-])=O)C(F)(F)F InChI=1/C13H5ClF6N4O5/c14-6-1-4(12(15,16)17)3-21-11(6)22-8-7(23(26)27)2-5(13(18,19)20)10(25)9(8)24(28)29/h1-3,25H,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is a metabolite of the substance 5-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-4,6-dinitro-o-cresol 3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-2,4-dinitro-6-(trifluoromethyl)phenol Not in list C13H5ClF6N4O5 [O-][N+](=O)c2cc(c(O)c(c2Nc1ncc(cc1Cl)C(F)(F)F)[N+]([O-])=O)C(F)(F)F InChI=1/C13H5ClF6N4O5/c14-6-1-4(12(15,16)17)3-21-11(6)22-8-7(23(26)27)2-5(13(18,19)20)10(25)9(8)24(28)29/h1-3,25H,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is a metabolite of the substance 5-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-4,6-dinitro-o-cresol 3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-2,4-dinitro-6-(trifluoromethyl)phenol Not in list C13H5ClF6N4O5 [O-][N+](=O)c2cc(c(O)c(c2Nc1ncc(cc1Cl)C(F)(F)F)[N+]([O-])=O)C(F)(F)F InChI=1/C13H5ClF6N4O5/c14-6-1-4(12(15,16)17)3-21-11(6)22-8-7(23(26)27)2-5(13(18,19)20)10(25)9(8)24(28)29/h1-3,25H,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is a metabolite of the substance 5-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-4,6-dinitro-o-cresol 3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-2,4-dinitro-6-(trifluoromethyl)phenol Not in list C13H5ClF6N4O5 [O-][N+](=O)c2cc(c(O)c(c2Nc1ncc(cc1Cl)C(F)(F)F)[N+]([O-])=O)C(F)(F)F InChI=1/C13H5ClF6N4O5/c14-6-1-4(12(15,16)17)3-21-11(6)22-8-7(23(26)27)2-5(13(18,19)20)10(25)9(8)24(28)29/h1-3,25H,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is a metabolite of the substance 5-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-4,6-dinitro-o-cresol 3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-2,4-dinitro-6-(trifluoromethyl)phenol Not in list C13H5ClF6N4O5 [O-][N+](=O)c2cc(c(O)c(c2Nc1ncc(cc1Cl)C(F)(F)F)[N+]([O-])=O)C(F)(F)F InChI=1/C13H5ClF6N4O5/c14-6-1-4(12(15,16)17)3-21-11(6)22-8-7(23(26)27)2-5(13(18,19)20)10(25)9(8)24(28)29/h1-3,25H,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is a metabolite of the substance 5-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-4,6-dinitro-o-cresol 3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-2,4-dinitro-6-(trifluoromethyl)phenol Not in list C13H5ClF6N4O5 [O-][N+](=O)c2cc(c(O)c(c2Nc1ncc(cc1Cl)C(F)(F)F)[N+]([O-])=O)C(F)(F)F InChI=1/C13H5ClF6N4O5/c14-6-1-4(12(15,16)17)3-21-11(6)22-8-7(23(26)27)2-5(13(18,19)20)10(25)9(8)24(28)29/h1-3,25H,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is a metabolite of the substance 5-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-4,6-dinitro-o-cresol 3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-2,4-dinitro-6-(trifluoromethyl)phenol Not in list C13H5ClF6N4O5 [O-][N+](=O)c2cc(c(O)c(c2Nc1ncc(cc1Cl)C(F)(F)F)[N+]([O-])=O)C(F)(F)F InChI=1/C13H5ClF6N4O5/c14-6-1-4(12(15,16)17)3-21-11(6)22-8-7(23(26)27)2-5(13(18,19)20)10(25)9(8)24(28)29/h1-3,25H,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is a metabolite of the substance 5-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-4,6-dinitro-o-cresol 3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-2,4-dinitro-6-(trifluoromethyl)phenol Not in list C13H5ClF6N4O5 [O-][N+](=O)c2cc(c(O)c(c2Nc1ncc(cc1Cl)C(F)(F)F)[N+]([O-])=O)C(F)(F)F InChI=1/C13H5ClF6N4O5/c14-6-1-4(12(15,16)17)3-21-11(6)22-8-7(23(26)27)2-5(13(18,19)20)10(25)9(8)24(28)29/h1-3,25H,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is a metabolite of the substance 5-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-4,6-dinitro-o-cresol 3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-2,4-dinitro-6-(trifluoromethyl)phenol Not in list C13H5ClF6N4O5 [O-][N+](=O)c2cc(c(O)c(c2Nc1ncc(cc1Cl)C(F)(F)F)[N+]([O-])=O)C(F)(F)F InChI=1/C13H5ClF6N4O5/c14-6-1-4(12(15,16)17)3-21-11(6)22-8-7(23(26)27)2-5(13(18,19)20)10(25)9(8)24(28)29/h1-3,25H,(H,21,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is a metabolite of the substance 2-chloro-6-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-5-nitro-m-toluidine 3-chloro-N1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-6-nitro-4-(trifluoromethyl)benzene-1,2-diamine Not in list C13H6Cl2F6N4O2 [O-][N+](=O)c2cc(c(Cl)c(N)c2Nc1ncc(cc1Cl)C(F)(F)F)C(F)(F)F InChI=1/C13H6Cl2F6N4O2/c14-6-1-4(12(16,17)18)3-23-11(6)24-10-7(25(26)27)2-5(13(19,20)21)8(15)9(10)22/h1-3H,22H2,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is a metabolite of the substance 2-chloro-6-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-5-nitro-m-toluidine 3-chloro-N1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-6-nitro-4-(trifluoromethyl)benzene-1,2-diamine Not in list C13H6Cl2F6N4O2 [O-][N+](=O)c2cc(c(Cl)c(N)c2Nc1ncc(cc1Cl)C(F)(F)F)C(F)(F)F InChI=1/C13H6Cl2F6N4O2/c14-6-1-4(12(16,17)18)3-23-11(6)24-10-7(25(26)27)2-5(13(19,20)21)8(15)9(10)22/h1-3H,22H2,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is a metabolite of the substance 2-chloro-6-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-5-nitro-m-toluidine 3-chloro-N1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-6-nitro-4-(trifluoromethyl)benzene-1,2-diamine Not in list C13H6Cl2F6N4O2 [O-][N+](=O)c2cc(c(Cl)c(N)c2Nc1ncc(cc1Cl)C(F)(F)F)C(F)(F)F InChI=1/C13H6Cl2F6N4O2/c14-6-1-4(12(16,17)18)3-23-11(6)24-10-7(25(26)27)2-5(13(19,20)21)8(15)9(10)22/h1-3H,22H2,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is a metabolite of the substance 2-chloro-6-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-5-nitro-m-toluidine 3-chloro-N1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-6-nitro-4-(trifluoromethyl)benzene-1,2-diamine Not in list C13H6Cl2F6N4O2 [O-][N+](=O)c2cc(c(Cl)c(N)c2Nc1ncc(cc1Cl)C(F)(F)F)C(F)(F)F InChI=1/C13H6Cl2F6N4O2/c14-6-1-4(12(16,17)18)3-23-11(6)24-10-7(25(26)27)2-5(13(19,20)21)8(15)9(10)22/h1-3H,22H2,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is a metabolite of the substance 2-chloro-6-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-5-nitro-m-toluidine 3-chloro-N1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-6-nitro-4-(trifluoromethyl)benzene-1,2-diamine Not in list C13H6Cl2F6N4O2 [O-][N+](=O)c2cc(c(Cl)c(N)c2Nc1ncc(cc1Cl)C(F)(F)F)C(F)(F)F InChI=1/C13H6Cl2F6N4O2/c14-6-1-4(12(16,17)18)3-23-11(6)24-10-7(25(26)27)2-5(13(19,20)21)8(15)9(10)22/h1-3H,22H2,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is a metabolite of the substance 2-chloro-6-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-5-nitro-m-toluidine 3-chloro-N1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-6-nitro-4-(trifluoromethyl)benzene-1,2-diamine Not in list C13H6Cl2F6N4O2 [O-][N+](=O)c2cc(c(Cl)c(N)c2Nc1ncc(cc1Cl)C(F)(F)F)C(F)(F)F InChI=1/C13H6Cl2F6N4O2/c14-6-1-4(12(16,17)18)3-23-11(6)24-10-7(25(26)27)2-5(13(19,20)21)8(15)9(10)22/h1-3H,22H2,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is a metabolite of the substance 2-chloro-6-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-5-nitro-m-toluidine 3-chloro-N1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-6-nitro-4-(trifluoromethyl)benzene-1,2-diamine Not in list C13H6Cl2F6N4O2 [O-][N+](=O)c2cc(c(Cl)c(N)c2Nc1ncc(cc1Cl)C(F)(F)F)C(F)(F)F InChI=1/C13H6Cl2F6N4O2/c14-6-1-4(12(16,17)18)3-23-11(6)24-10-7(25(26)27)2-5(13(19,20)21)8(15)9(10)22/h1-3H,22H2,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is a metabolite of the substance 2-chloro-6-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-5-nitro-m-toluidine 3-chloro-N1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-6-nitro-4-(trifluoromethyl)benzene-1,2-diamine Not in list C13H6Cl2F6N4O2 [O-][N+](=O)c2cc(c(Cl)c(N)c2Nc1ncc(cc1Cl)C(F)(F)F)C(F)(F)F InChI=1/C13H6Cl2F6N4O2/c14-6-1-4(12(16,17)18)3-23-11(6)24-10-7(25(26)27)2-5(13(19,20)21)8(15)9(10)22/h1-3H,22H2,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is a metabolite of the substance 2-chloro-6-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-5-nitro-m-toluidine 3-chloro-N1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-6-nitro-4-(trifluoromethyl)benzene-1,2-diamine Not in list C13H6Cl2F6N4O2 [O-][N+](=O)c2cc(c(Cl)c(N)c2Nc1ncc(cc1Cl)C(F)(F)F)C(F)(F)F InChI=1/C13H6Cl2F6N4O2/c14-6-1-4(12(16,17)18)3-23-11(6)24-10-7(25(26)27)2-5(13(19,20)21)8(15)9(10)22/h1-3H,22H2,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is a metabolite of the substance 2-chloro-6-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-5-nitro-m-toluidine 3-chloro-N1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-6-nitro-4-(trifluoromethyl)benzene-1,2-diamine Not in list C13H6Cl2F6N4O2 [O-][N+](=O)c2cc(c(Cl)c(N)c2Nc1ncc(cc1Cl)C(F)(F)F)C(F)(F)F InChI=1/C13H6Cl2F6N4O2/c14-6-1-4(12(16,17)18)3-23-11(6)24-10-7(25(26)27)2-5(13(19,20)21)8(15)9(10)22/h1-3H,22H2,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is a metabolite of the substance 5-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-4,6-dinitro-o-cresol 3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-2,4-dinitro-6-(trifluoromethyl)phenol Not in list C13H5ClF6N4O5 [O-][N+](=O)c2cc(c(O)c(c2Nc1ncc(cc1Cl)C(F)(F)F)[N+]([O-])=O)C(F)(F)F InChI=1/C13H5ClF6N4O5/c14-6-1-4(12(15,16)17)3-21-11(6)22-8-7(23(26)27)2-5(13(18,19)20)10(25)9(8)24(28)29/h1-3,25H,(H,21,22) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Not reported 6 Male oral: gavage 72.0000000000 h yes not applicable Negative no evidence RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is a metabolite of the substance 5-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-4,6-dinitro-o-cresol 3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-2,4-dinitro-6-(trifluoromethyl)phenol Not in list C13H5ClF6N4O5 [O-][N+](=O)c2cc(c(O)c(c2Nc1ncc(cc1Cl)C(F)(F)F)[N+]([O-])=O)C(F)(F)F InChI=1/C13H5ClF6N4O5/c14-6-1-4(12(15,16)17)3-21-11(6)22-8-7(23(26)27)2-5(13(18,19)20)10(25)9(8)24(28)29/h1-3,25H,(H,21,22) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Not reported 6 Male oral: gavage 48.0000000000 h yes not applicable Negative no evidence RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is a metabolite of the substance 5-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-4,6-dinitro-o-cresol 3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-2,4-dinitro-6-(trifluoromethyl)phenol Not in list C13H5ClF6N4O5 [O-][N+](=O)c2cc(c(O)c(c2Nc1ncc(cc1Cl)C(F)(F)F)[N+]([O-])=O)C(F)(F)F InChI=1/C13H5ClF6N4O5/c14-6-1-4(12(15,16)17)3-21-11(6)22-8-7(23(26)27)2-5(13(18,19)20)10(25)9(8)24(28)29/h1-3,25H,(H,21,22) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Not reported 6 Male oral: gavage 24.0000000000 h yes not applicable Negative no evidence RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is a metabolite of the substance 5-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-4,6-dinitro-o-cresol 3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-2,4-dinitro-6-(trifluoromethyl)phenol Not in list C13H5ClF6N4O5 [O-][N+](=O)c2cc(c(O)c(c2Nc1ncc(cc1Cl)C(F)(F)F)[N+]([O-])=O)C(F)(F)F InChI=1/C13H5ClF6N4O5/c14-6-1-4(12(15,16)17)3-21-11(6)22-8-7(23(26)27)2-5(13(18,19)20)10(25)9(8)24(28)29/h1-3,25H,(H,21,22) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Not reported 6 Male oral: gavage 16.0000000000 h yes not applicable Negative no evidence RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is a metabolite of the substance 5-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-4,6-dinitro-o-cresol 3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-2,4-dinitro-6-(trifluoromethyl)phenol Not in list C13H5ClF6N4O5 [O-][N+](=O)c2cc(c(O)c(c2Nc1ncc(cc1Cl)C(F)(F)F)[N+]([O-])=O)C(F)(F)F InChI=1/C13H5ClF6N4O5/c14-6-1-4(12(15,16)17)3-21-11(6)22-8-7(23(26)27)2-5(13(18,19)20)10(25)9(8)24(28)29/h1-3,25H,(H,21,22) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Not reported 6 Female oral: gavage 72.0000000000 h yes not applicable Negative no evidence RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is a metabolite of the substance 5-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-4,6-dinitro-o-cresol 3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-2,4-dinitro-6-(trifluoromethyl)phenol Not in list C13H5ClF6N4O5 [O-][N+](=O)c2cc(c(O)c(c2Nc1ncc(cc1Cl)C(F)(F)F)[N+]([O-])=O)C(F)(F)F InChI=1/C13H5ClF6N4O5/c14-6-1-4(12(15,16)17)3-21-11(6)22-8-7(23(26)27)2-5(13(18,19)20)10(25)9(8)24(28)29/h1-3,25H,(H,21,22) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Not reported 6 Female oral: gavage 48.0000000000 h yes not applicable Negative no evidence RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is a metabolite of the substance 5-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-4,6-dinitro-o-cresol 3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-2,4-dinitro-6-(trifluoromethyl)phenol Not in list C13H5ClF6N4O5 [O-][N+](=O)c2cc(c(O)c(c2Nc1ncc(cc1Cl)C(F)(F)F)[N+]([O-])=O)C(F)(F)F InChI=1/C13H5ClF6N4O5/c14-6-1-4(12(15,16)17)3-21-11(6)22-8-7(23(26)27)2-5(13(18,19)20)10(25)9(8)24(28)29/h1-3,25H,(H,21,22) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Not reported 6 Female oral: gavage 24.0000000000 h yes not applicable Negative no evidence RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fluazinam 79622-59-6 single chemical entity Component is a metabolite of the substance 5-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-4,6-dinitro-o-cresol 3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-2,4-dinitro-6-(trifluoromethyl)phenol Not in list C13H5ClF6N4O5 [O-][N+](=O)c2cc(c(O)c(c2Nc1ncc(cc1Cl)C(F)(F)F)[N+]([O-])=O)C(F)(F)F InChI=1/C13H5ClF6N4O5/c14-6-1-4(12(15,16)17)3-21-11(6)22-8-7(23(26)27)2-5(13(18,19)20)10(25)9(8)24(28)29/h1-3,25H,(H,21,22) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Not reported 6 Female oral: gavage 16.0000000000 h yes not applicable Negative no evidence RMS: Austria Fluazinam 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam 29Jul2008 2008 doi:10.2903/j.efsa.2008.137r
+Fenamidone 605-252-0 161326-34-7 single chemical entity Component is identical to the substance Fenamidone 605-252-0 161326-34-7 (S)-5-methyl-2-methylthio-5-phenyl-3-phenylamino-3,5-dihydroimidazol-4-one Fenamidone C17H17N3OS CC1(C(=O)N(C(=N1)SC)NC2=CC=CC=C2)C3=CC=CC=C3 InChI=1S/C17H17N3OS/c1-17(13-9-5-3-6-10-13)15(21)20(16(18-17)22-2)19-14-11-7-4-8-12-14/h3-12,19H,1-2H3/t17-/m0/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Czech republic - CoRMS: France Fenamidone (Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fenamidone 22Feb2016 2016 doi:10.2903/j.efsa.2016.4406
+Fenamidone 605-252-0 161326-34-7 single chemical entity Component is identical to the substance Fenamidone 605-252-0 161326-34-7 (S)-5-methyl-2-methylthio-5-phenyl-3-phenylamino-3,5-dihydroimidazol-4-one Fenamidone C17H17N3OS CC1(C(=O)N(C(=N1)SC)NC2=CC=CC=C2)C3=CC=CC=C3 InChI=1S/C17H17N3OS/c1-17(13-9-5-3-6-10-13)15(21)20(16(18-17)22-2)19-14-11-7-4-8-12-14/h3-12,19H,1-2H3/t17-/m0/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Czech republic - CoRMS: France Fenamidone (Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fenamidone 22Feb2016 2016 doi:10.2903/j.efsa.2016.4406
+Fenamidone 605-252-0 161326-34-7 single chemical entity Component is identical to the substance Fenamidone 605-252-0 161326-34-7 (S)-5-methyl-2-methylthio-5-phenyl-3-phenylamino-3,5-dihydroimidazol-4-one Fenamidone C17H17N3OS CC1(C(=O)N(C(=N1)SC)NC2=CC=CC=C2)C3=CC=CC=C3 InChI=1S/C17H17N3OS/c1-17(13-9-5-3-6-10-13)15(21)20(16(18-17)22-2)19-14-11-7-4-8-12-14/h3-12,19H,1-2H3/t17-/m0/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Czech republic - CoRMS: France Fenamidone (Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fenamidone 22Feb2016 2016 doi:10.2903/j.efsa.2016.4406
+Fenamidone 605-252-0 161326-34-7 single chemical entity Component is identical to the substance Fenamidone 605-252-0 161326-34-7 (S)-5-methyl-2-methylthio-5-phenyl-3-phenylamino-3,5-dihydroimidazol-4-one Fenamidone C17H17N3OS CC1(C(=O)N(C(=N1)SC)NC2=CC=CC=C2)C3=CC=CC=C3 InChI=1S/C17H17N3OS/c1-17(13-9-5-3-6-10-13)15(21)20(16(18-17)22-2)19-14-11-7-4-8-12-14/h3-12,19H,1-2H3/t17-/m0/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Czech republic - CoRMS: France Fenamidone (Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fenamidone 22Feb2016 2016 doi:10.2903/j.efsa.2016.4406
+Fenamidone 605-252-0 161326-34-7 single chemical entity Component is identical to the substance Fenamidone 605-252-0 161326-34-7 (S)-5-methyl-2-methylthio-5-phenyl-3-phenylamino-3,5-dihydroimidazol-4-one Fenamidone C17H17N3OS CC1(C(=O)N(C(=N1)SC)NC2=CC=CC=C2)C3=CC=CC=C3 InChI=1S/C17H17N3OS/c1-17(13-9-5-3-6-10-13)15(21)20(16(18-17)22-2)19-14-11-7-4-8-12-14/h3-12,19H,1-2H3/t17-/m0/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Czech republic - CoRMS: France Fenamidone (Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fenamidone 22Feb2016 2016 doi:10.2903/j.efsa.2016.4406
+Fenamidone 605-252-0 161326-34-7 single chemical entity Component is identical to the substance Fenamidone 605-252-0 161326-34-7 (S)-5-methyl-2-methylthio-5-phenyl-3-phenylamino-3,5-dihydroimidazol-4-one Fenamidone C17H17N3OS CC1(C(=O)N(C(=N1)SC)NC2=CC=CC=C2)C3=CC=CC=C3 InChI=1S/C17H17N3OS/c1-17(13-9-5-3-6-10-13)15(21)20(16(18-17)22-2)19-14-11-7-4-8-12-14/h3-12,19H,1-2H3/t17-/m0/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Czech republic - CoRMS: France Fenamidone (Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fenamidone 22Feb2016 2016 doi:10.2903/j.efsa.2016.4406
+Fenamidone 605-252-0 161326-34-7 single chemical entity Component is identical to the substance Fenamidone 605-252-0 161326-34-7 (S)-5-methyl-2-methylthio-5-phenyl-3-phenylamino-3,5-dihydroimidazol-4-one Fenamidone C17H17N3OS CC1(C(=O)N(C(=N1)SC)NC2=CC=CC=C2)C3=CC=CC=C3 InChI=1S/C17H17N3OS/c1-17(13-9-5-3-6-10-13)15(21)20(16(18-17)22-2)19-14-11-7-4-8-12-14/h3-12,19H,1-2H3/t17-/m0/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Czech republic - CoRMS: France Fenamidone (Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fenamidone 22Feb2016 2016 doi:10.2903/j.efsa.2016.4406
+Fenamidone 605-252-0 161326-34-7 single chemical entity Component is identical to the substance Fenamidone 605-252-0 161326-34-7 (S)-5-methyl-2-methylthio-5-phenyl-3-phenylamino-3,5-dihydroimidazol-4-one Fenamidone C17H17N3OS CC1(C(=O)N(C(=N1)SC)NC2=CC=CC=C2)C3=CC=CC=C3 InChI=1S/C17H17N3OS/c1-17(13-9-5-3-6-10-13)15(21)20(16(18-17)22-2)19-14-11-7-4-8-12-14/h3-12,19H,1-2H3/t17-/m0/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Czech republic - CoRMS: France Fenamidone (Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fenamidone 22Feb2016 2016 doi:10.2903/j.efsa.2016.4406
+Fenamidone 605-252-0 161326-34-7 single chemical entity Component is identical to the substance Fenamidone 605-252-0 161326-34-7 (S)-5-methyl-2-methylthio-5-phenyl-3-phenylamino-3,5-dihydroimidazol-4-one Fenamidone C17H17N3OS CC1(C(=O)N(C(=N1)SC)NC2=CC=CC=C2)C3=CC=CC=C3 InChI=1S/C17H17N3OS/c1-17(13-9-5-3-6-10-13)15(21)20(16(18-17)22-2)19-14-11-7-4-8-12-14/h3-12,19H,1-2H3/t17-/m0/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Czech republic - CoRMS: France Fenamidone (Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fenamidone 22Feb2016 2016 doi:10.2903/j.efsa.2016.4406
+Fenamidone 605-252-0 161326-34-7 single chemical entity Component is identical to the substance Fenamidone 605-252-0 161326-34-7 (S)-5-methyl-2-methylthio-5-phenyl-3-phenylamino-3,5-dihydroimidazol-4-one Fenamidone C17H17N3OS CC1(C(=O)N(C(=N1)SC)NC2=CC=CC=C2)C3=CC=CC=C3 InChI=1S/C17H17N3OS/c1-17(13-9-5-3-6-10-13)15(21)20(16(18-17)22-2)19-14-11-7-4-8-12-14/h3-12,19H,1-2H3/t17-/m0/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Czech republic - CoRMS: France Fenamidone (Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fenamidone 22Feb2016 2016 doi:10.2903/j.efsa.2016.4406
+Fenamidone 605-252-0 161326-34-7 single chemical entity Component is identical to the substance Fenamidone 605-252-0 161326-34-7 (S)-5-methyl-2-methylthio-5-phenyl-3-phenylamino-3,5-dihydroimidazol-4-one Fenamidone C17H17N3OS CC1(C(=O)N(C(=N1)SC)NC2=CC=CC=C2)C3=CC=CC=C3 InChI=1S/C17H17N3OS/c1-17(13-9-5-3-6-10-13)15(21)20(16(18-17)22-2)19-14-11-7-4-8-12-14/h3-12,19H,1-2H3/t17-/m0/s1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Positive RMS: Czech republic - CoRMS: France Fenamidone (Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fenamidone 22Feb2016 2016 doi:10.2903/j.efsa.2016.4406
+Fenamidone 605-252-0 161326-34-7 single chemical entity Component is identical to the substance Fenamidone 605-252-0 161326-34-7 (S)-5-methyl-2-methylthio-5-phenyl-3-phenylamino-3,5-dihydroimidazol-4-one Fenamidone C17H17N3OS CC1(C(=O)N(C(=N1)SC)NC2=CC=CC=C2)C3=CC=CC=C3 InChI=1S/C17H17N3OS/c1-17(13-9-5-3-6-10-13)15(21)20(16(18-17)22-2)19-14-11-7-4-8-12-14/h3-12,19H,1-2H3/t17-/m0/s1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Positive RMS: Czech republic - CoRMS: France Fenamidone (Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fenamidone 22Feb2016 2016 doi:10.2903/j.efsa.2016.4406
+Fenamidone 605-252-0 161326-34-7 single chemical entity Component is identical to the substance Fenamidone 605-252-0 161326-34-7 (S)-5-methyl-2-methylthio-5-phenyl-3-phenylamino-3,5-dihydroimidazol-4-one Fenamidone C17H17N3OS CC1(C(=O)N(C(=N1)SC)NC2=CC=CC=C2)C3=CC=CC=C3 InChI=1S/C17H17N3OS/c1-17(13-9-5-3-6-10-13)15(21)20(16(18-17)22-2)19-14-11-7-4-8-12-14/h3-12,19H,1-2H3/t17-/m0/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative small colonies RMS: Czech republic - CoRMS: France Fenamidone (Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fenamidone 22Feb2016 2016 doi:10.2903/j.efsa.2016.4406
+Fenamidone 605-252-0 161326-34-7 single chemical entity Component is identical to the substance Fenamidone 605-252-0 161326-34-7 (S)-5-methyl-2-methylthio-5-phenyl-3-phenylamino-3,5-dihydroimidazol-4-one Fenamidone C17H17N3OS CC1(C(=O)N(C(=N1)SC)NC2=CC=CC=C2)C3=CC=CC=C3 InChI=1S/C17H17N3OS/c1-17(13-9-5-3-6-10-13)15(21)20(16(18-17)22-2)19-14-11-7-4-8-12-14/h3-12,19H,1-2H3/t17-/m0/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Positive large colonies RMS: Czech republic - CoRMS: France Fenamidone (Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fenamidone 22Feb2016 2016 doi:10.2903/j.efsa.2016.4406
+Fenamidone 605-252-0 161326-34-7 single chemical entity Component is identical to the substance Fenamidone 605-252-0 161326-34-7 (S)-5-methyl-2-methylthio-5-phenyl-3-phenylamino-3,5-dihydroimidazol-4-one Fenamidone C17H17N3OS CC1(C(=O)N(C(=N1)SC)NC2=CC=CC=C2)C3=CC=CC=C3 InChI=1S/C17H17N3OS/c1-17(13-9-5-3-6-10-13)15(21)20(16(18-17)22-2)19-14-11-7-4-8-12-14/h3-12,19H,1-2H3/t17-/m0/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Positive small colonies RMS: Czech republic - CoRMS: France Fenamidone (Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fenamidone 22Feb2016 2016 doi:10.2903/j.efsa.2016.4406
+Fenamidone 605-252-0 161326-34-7 single chemical entity Component is identical to the substance Fenamidone 605-252-0 161326-34-7 (S)-5-methyl-2-methylthio-5-phenyl-3-phenylamino-3,5-dihydroimidazol-4-one Fenamidone C17H17N3OS CC1(C(=O)N(C(=N1)SC)NC2=CC=CC=C2)C3=CC=CC=C3 InChI=1S/C17H17N3OS/c1-17(13-9-5-3-6-10-13)15(21)20(16(18-17)22-2)19-14-11-7-4-8-12-14/h3-12,19H,1-2H3/t17-/m0/s1 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative large colonies RMS: Czech republic - CoRMS: France Fenamidone (Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fenamidone 22Feb2016 2016 doi:10.2903/j.efsa.2016.4406
+Fenamidone 605-252-0 161326-34-7 single chemical entity Component is identical to the substance Fenamidone 605-252-0 161326-34-7 (S)-5-methyl-2-methylthio-5-phenyl-3-phenylamino-3,5-dihydroimidazol-4-one Fenamidone C17H17N3OS CC1(C(=O)N(C(=N1)SC)NC2=CC=CC=C2)C3=CC=CC=C3 InChI=1S/C17H17N3OS/c1-17(13-9-5-3-6-10-13)15(21)20(16(18-17)22-2)19-14-11-7-4-8-12-14/h3-12,19H,1-2H3/t17-/m0/s1 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Czech republic - CoRMS: France Fenamidone (Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fenamidone 22Feb2016 2016 doi:10.2903/j.efsa.2016.4406
+Fenamidone 605-252-0 161326-34-7 single chemical entity Component is identical to the substance Fenamidone 605-252-0 161326-34-7 (S)-5-methyl-2-methylthio-5-phenyl-3-phenylamino-3,5-dihydroimidazol-4-one Fenamidone C17H17N3OS CC1(C(=O)N(C(=N1)SC)NC2=CC=CC=C2)C3=CC=CC=C3 InChI=1S/C17H17N3OS/c1-17(13-9-5-3-6-10-13)15(21)20(16(18-17)22-2)19-14-11-7-4-8-12-14/h3-12,19H,1-2H3/t17-/m0/s1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Not reported 10 Male/Female intraperitoneal 48.0000000000 h yes not applicable Negative direct evidence-cytotoxicity RMS: Czech republic - CoRMS: France Fenamidone (Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fenamidone 22Feb2016 2016 doi:10.2903/j.efsa.2016.4406
+Fenamidone 605-252-0 161326-34-7 single chemical entity Component is identical to the substance Fenamidone 605-252-0 161326-34-7 (S)-5-methyl-2-methylthio-5-phenyl-3-phenylamino-3,5-dihydroimidazol-4-one Fenamidone C17H17N3OS CC1(C(=O)N(C(=N1)SC)NC2=CC=CC=C2)C3=CC=CC=C3 InChI=1S/C17H17N3OS/c1-17(13-9-5-3-6-10-13)15(21)20(16(18-17)22-2)19-14-11-7-4-8-12-14/h3-12,19H,1-2H3/t17-/m0/s1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Not reported 10 Male/Female intraperitoneal 24.0000000000 h yes not applicable Negative direct evidence-cytotoxicity RMS: Czech republic - CoRMS: France Fenamidone (Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fenamidone 22Feb2016 2016 doi:10.2903/j.efsa.2016.4406
+Fenamidone 605-252-0 161326-34-7 single chemical entity Component is identical to the substance Fenamidone 605-252-0 161326-34-7 (S)-5-methyl-2-methylthio-5-phenyl-3-phenylamino-3,5-dihydroimidazol-4-one Fenamidone C17H17N3OS CC1(C(=O)N(C(=N1)SC)NC2=CC=CC=C2)C3=CC=CC=C3 InChI=1S/C17H17N3OS/c1-17(13-9-5-3-6-10-13)15(21)20(16(18-17)22-2)19-14-11-7-4-8-12-14/h3-12,19H,1-2H3/t17-/m0/s1 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Wistar 5 Male oral: unspecified 18.0000000000 h yes not applicable Negative RMS: Czech republic - CoRMS: France Fenamidone (Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fenamidone 22Feb2016 2016 doi:10.2903/j.efsa.2016.4406
+Fenamidone 605-252-0 161326-34-7 single chemical entity Component is identical to the substance Fenamidone 605-252-0 161326-34-7 (S)-5-methyl-2-methylthio-5-phenyl-3-phenylamino-3,5-dihydroimidazol-4-one Fenamidone C17H17N3OS CC1(C(=O)N(C(=N1)SC)NC2=CC=CC=C2)C3=CC=CC=C3 InChI=1S/C17H17N3OS/c1-17(13-9-5-3-6-10-13)15(21)20(16(18-17)22-2)19-14-11-7-4-8-12-14/h3-12,19H,1-2H3/t17-/m0/s1 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Wistar 5 Male oral: unspecified 4.0000000000 h yes not applicable Negative RMS: Czech republic - CoRMS: France Fenamidone (Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fenamidone 22Feb2016 2016 doi:10.2903/j.efsa.2016.4406
+Fenamidone 605-252-0 161326-34-7 single chemical entity Component is a metabolite of the substance (5S)-5-methyl-5-phenylimidazolidine-2,4-dione (5S)-5-methyl-5-phenylimidazolidine-2,4-dione Not in list C10H10N2O2 C[C@]1(NC(=O)NC1=O)c2ccccc2 InChI=1/C10H10N2O2/c1-10(7-5-3-2-4-6-7)8(13)11-9(14)12-10/h2-6H,1H3,(H2,11,12,13,14)/t10-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Czech republic - CoRMS: France Fenamidone (Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fenamidone 22Feb2016 2016 doi:10.2903/j.efsa.2016.4406
+Fenamidone 605-252-0 161326-34-7 single chemical entity Component is a metabolite of the substance (5S)-5-methyl-5-phenylimidazolidine-2,4-dione (5S)-5-methyl-5-phenylimidazolidine-2,4-dione Not in list C10H10N2O2 C[C@]1(NC(=O)NC1=O)c2ccccc2 InChI=1/C10H10N2O2/c1-10(7-5-3-2-4-6-7)8(13)11-9(14)12-10/h2-6H,1H3,(H2,11,12,13,14)/t10-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Czech republic - CoRMS: France Fenamidone (Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fenamidone 22Feb2016 2016 doi:10.2903/j.efsa.2016.4406
+Fenamidone 605-252-0 161326-34-7 single chemical entity Component is a metabolite of the substance (5S)-5-methyl-5-phenylimidazolidine-2,4-dione (5S)-5-methyl-5-phenylimidazolidine-2,4-dione Not in list C10H10N2O2 C[C@]1(NC(=O)NC1=O)c2ccccc2 InChI=1/C10H10N2O2/c1-10(7-5-3-2-4-6-7)8(13)11-9(14)12-10/h2-6H,1H3,(H2,11,12,13,14)/t10-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Czech republic - CoRMS: France Fenamidone (Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fenamidone 22Feb2016 2016 doi:10.2903/j.efsa.2016.4406
+Fenamidone 605-252-0 161326-34-7 single chemical entity Component is a metabolite of the substance (5S)-5-methyl-5-phenylimidazolidine-2,4-dione (5S)-5-methyl-5-phenylimidazolidine-2,4-dione Not in list C10H10N2O2 C[C@]1(NC(=O)NC1=O)c2ccccc2 InChI=1/C10H10N2O2/c1-10(7-5-3-2-4-6-7)8(13)11-9(14)12-10/h2-6H,1H3,(H2,11,12,13,14)/t10-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Czech republic - CoRMS: France Fenamidone (Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fenamidone 22Feb2016 2016 doi:10.2903/j.efsa.2016.4406
+Fenamidone 605-252-0 161326-34-7 single chemical entity Component is a metabolite of the substance (5S)-5-methyl-5-phenylimidazolidine-2,4-dione (5S)-5-methyl-5-phenylimidazolidine-2,4-dione Not in list C10H10N2O2 C[C@]1(NC(=O)NC1=O)c2ccccc2 InChI=1/C10H10N2O2/c1-10(7-5-3-2-4-6-7)8(13)11-9(14)12-10/h2-6H,1H3,(H2,11,12,13,14)/t10-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Czech republic - CoRMS: France Fenamidone (Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fenamidone 22Feb2016 2016 doi:10.2903/j.efsa.2016.4406
+Fenamidone 605-252-0 161326-34-7 single chemical entity Component is a metabolite of the substance (5S)-5-methyl-5-phenylimidazolidine-2,4-dione (5S)-5-methyl-5-phenylimidazolidine-2,4-dione Not in list C10H10N2O2 C[C@]1(NC(=O)NC1=O)c2ccccc2 InChI=1/C10H10N2O2/c1-10(7-5-3-2-4-6-7)8(13)11-9(14)12-10/h2-6H,1H3,(H2,11,12,13,14)/t10-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Czech republic - CoRMS: France Fenamidone (Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fenamidone 22Feb2016 2016 doi:10.2903/j.efsa.2016.4406
+Fenamidone 605-252-0 161326-34-7 single chemical entity Component is a metabolite of the substance (5S)-5-methyl-5-phenylimidazolidine-2,4-dione (5S)-5-methyl-5-phenylimidazolidine-2,4-dione Not in list C10H10N2O2 C[C@]1(NC(=O)NC1=O)c2ccccc2 InChI=1/C10H10N2O2/c1-10(7-5-3-2-4-6-7)8(13)11-9(14)12-10/h2-6H,1H3,(H2,11,12,13,14)/t10-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Czech republic - CoRMS: France Fenamidone (Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fenamidone 22Feb2016 2016 doi:10.2903/j.efsa.2016.4406
+Fenamidone 605-252-0 161326-34-7 single chemical entity Component is a metabolite of the substance (5S)-5-methyl-5-phenylimidazolidine-2,4-dione (5S)-5-methyl-5-phenylimidazolidine-2,4-dione Not in list C10H10N2O2 C[C@]1(NC(=O)NC1=O)c2ccccc2 InChI=1/C10H10N2O2/c1-10(7-5-3-2-4-6-7)8(13)11-9(14)12-10/h2-6H,1H3,(H2,11,12,13,14)/t10-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Czech republic - CoRMS: France Fenamidone (Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fenamidone 22Feb2016 2016 doi:10.2903/j.efsa.2016.4406
+Fenamidone 605-252-0 161326-34-7 single chemical entity Component is a metabolite of the substance (5S)-5-methyl-5-phenylimidazolidine-2,4-dione (5S)-5-methyl-5-phenylimidazolidine-2,4-dione Not in list C10H10N2O2 C[C@]1(NC(=O)NC1=O)c2ccccc2 InChI=1/C10H10N2O2/c1-10(7-5-3-2-4-6-7)8(13)11-9(14)12-10/h2-6H,1H3,(H2,11,12,13,14)/t10-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Czech republic - CoRMS: France Fenamidone (Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fenamidone 22Feb2016 2016 doi:10.2903/j.efsa.2016.4406
+Fenamidone 605-252-0 161326-34-7 single chemical entity Component is a metabolite of the substance (5S)-5-methyl-5-phenylimidazolidine-2,4-dione (5S)-5-methyl-5-phenylimidazolidine-2,4-dione Not in list C10H10N2O2 C[C@]1(NC(=O)NC1=O)c2ccccc2 InChI=1/C10H10N2O2/c1-10(7-5-3-2-4-6-7)8(13)11-9(14)12-10/h2-6H,1H3,(H2,11,12,13,14)/t10-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Czech republic - CoRMS: France Fenamidone (Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fenamidone 22Feb2016 2016 doi:10.2903/j.efsa.2016.4406
+Fenamidone 605-252-0 161326-34-7 single chemical entity Component is a metabolite of the substance (5S)-5-methyl-5-phenylimidazolidine-2,4-dione (5S)-5-methyl-5-phenylimidazolidine-2,4-dione Not in list C10H10N2O2 C[C@]1(NC(=O)NC1=O)c2ccccc2 InChI=1/C10H10N2O2/c1-10(7-5-3-2-4-6-7)8(13)11-9(14)12-10/h2-6H,1H3,(H2,11,12,13,14)/t10-/m0/s1 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Czech republic - CoRMS: France Fenamidone (Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fenamidone 22Feb2016 2016 doi:10.2903/j.efsa.2016.4406
+Fenamidone 605-252-0 161326-34-7 single chemical entity Component is a metabolite of the substance (5S)-5-methyl-5-phenylimidazolidine-2,4-dione (5S)-5-methyl-5-phenylimidazolidine-2,4-dione Not in list C10H10N2O2 C[C@]1(NC(=O)NC1=O)c2ccccc2 InChI=1/C10H10N2O2/c1-10(7-5-3-2-4-6-7)8(13)11-9(14)12-10/h2-6H,1H3,(H2,11,12,13,14)/t10-/m0/s1 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Czech republic - CoRMS: France Fenamidone (Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fenamidone 22Feb2016 2016 doi:10.2903/j.efsa.2016.4406
+Fenamidone 605-252-0 161326-34-7 single chemical entity Component is a metabolite of the substance (5S)-5-methyl-5-phenylimidazolidine-2,4-dione (5S)-5-methyl-5-phenylimidazolidine-2,4-dione Not in list C10H10N2O2 C[C@]1(NC(=O)NC1=O)c2ccccc2 InChI=1/C10H10N2O2/c1-10(7-5-3-2-4-6-7)8(13)11-9(14)12-10/h2-6H,1H3,(H2,11,12,13,14)/t10-/m0/s1 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 8 Male intraperitoneal 24.0000000000 h yes not applicable Negative direct evidence-cytotoxicity RMS: Czech republic - CoRMS: France Fenamidone (Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fenamidone 22Feb2016 2016 doi:10.2903/j.efsa.2016.4406
+Fenamidone 605-252-0 161326-34-7 single chemical entity Component is a metabolite of the substance (S)-5-Methyl-5-phenyl-3-(phenylamino)- 2,4-imidazolidine-dione (5S)-5-methyl-5-phenyl-3-(phenylamino)imidazolidine-2,4-dione Not in list C16H15N3O2 O=C2N(Nc1ccccc1)C(=O)N[C@@]2(C)c3ccccc3 InChI=1/C16H15N3O2/c1-16(12-8-4-2-5-9-12)14(20)19(15(21)17-16)18-13-10-6-3-7-11-13/h2-11,18H,1H3,(H,17,21)/t16-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Czech republic - CoRMS: France Fenamidone (Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fenamidone 22Feb2016 2016 doi:10.2903/j.efsa.2016.4406
+Fenamidone 605-252-0 161326-34-7 single chemical entity Component is a metabolite of the substance (S)-5-Methyl-5-phenyl-3-(phenylamino)- 2,4-imidazolidine-dione (5S)-5-methyl-5-phenyl-3-(phenylamino)imidazolidine-2,4-dione Not in list C16H15N3O2 O=C2N(Nc1ccccc1)C(=O)N[C@@]2(C)c3ccccc3 InChI=1/C16H15N3O2/c1-16(12-8-4-2-5-9-12)14(20)19(15(21)17-16)18-13-10-6-3-7-11-13/h2-11,18H,1H3,(H,17,21)/t16-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Czech republic - CoRMS: France Fenamidone (Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fenamidone 22Feb2016 2016 doi:10.2903/j.efsa.2016.4406
+Fenamidone 605-252-0 161326-34-7 single chemical entity Component is a metabolite of the substance (S)-5-Methyl-5-phenyl-3-(phenylamino)- 2,4-imidazolidine-dione (5S)-5-methyl-5-phenyl-3-(phenylamino)imidazolidine-2,4-dione Not in list C16H15N3O2 O=C2N(Nc1ccccc1)C(=O)N[C@@]2(C)c3ccccc3 InChI=1/C16H15N3O2/c1-16(12-8-4-2-5-9-12)14(20)19(15(21)17-16)18-13-10-6-3-7-11-13/h2-11,18H,1H3,(H,17,21)/t16-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Czech republic - CoRMS: France Fenamidone (Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fenamidone 22Feb2016 2016 doi:10.2903/j.efsa.2016.4406
+Fenamidone 605-252-0 161326-34-7 single chemical entity Component is a metabolite of the substance (S)-5-Methyl-5-phenyl-3-(phenylamino)- 2,4-imidazolidine-dione (5S)-5-methyl-5-phenyl-3-(phenylamino)imidazolidine-2,4-dione Not in list C16H15N3O2 O=C2N(Nc1ccccc1)C(=O)N[C@@]2(C)c3ccccc3 InChI=1/C16H15N3O2/c1-16(12-8-4-2-5-9-12)14(20)19(15(21)17-16)18-13-10-6-3-7-11-13/h2-11,18H,1H3,(H,17,21)/t16-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Czech republic - CoRMS: France Fenamidone (Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fenamidone 22Feb2016 2016 doi:10.2903/j.efsa.2016.4406
+Fenamidone 605-252-0 161326-34-7 single chemical entity Component is a metabolite of the substance (S)-5-Methyl-5-phenyl-3-(phenylamino)- 2,4-imidazolidine-dione (5S)-5-methyl-5-phenyl-3-(phenylamino)imidazolidine-2,4-dione Not in list C16H15N3O2 O=C2N(Nc1ccccc1)C(=O)N[C@@]2(C)c3ccccc3 InChI=1/C16H15N3O2/c1-16(12-8-4-2-5-9-12)14(20)19(15(21)17-16)18-13-10-6-3-7-11-13/h2-11,18H,1H3,(H,17,21)/t16-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Czech republic - CoRMS: France Fenamidone (Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fenamidone 22Feb2016 2016 doi:10.2903/j.efsa.2016.4406
+Fenamidone 605-252-0 161326-34-7 single chemical entity Component is a metabolite of the substance (S)-5-Methyl-5-phenyl-3-(phenylamino)- 2,4-imidazolidine-dione (5S)-5-methyl-5-phenyl-3-(phenylamino)imidazolidine-2,4-dione Not in list C16H15N3O2 O=C2N(Nc1ccccc1)C(=O)N[C@@]2(C)c3ccccc3 InChI=1/C16H15N3O2/c1-16(12-8-4-2-5-9-12)14(20)19(15(21)17-16)18-13-10-6-3-7-11-13/h2-11,18H,1H3,(H,17,21)/t16-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Czech republic - CoRMS: France Fenamidone (Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fenamidone 22Feb2016 2016 doi:10.2903/j.efsa.2016.4406
+Fenamidone 605-252-0 161326-34-7 single chemical entity Component is a metabolite of the substance (S)-5-Methyl-5-phenyl-3-(phenylamino)- 2,4-imidazolidine-dione (5S)-5-methyl-5-phenyl-3-(phenylamino)imidazolidine-2,4-dione Not in list C16H15N3O2 O=C2N(Nc1ccccc1)C(=O)N[C@@]2(C)c3ccccc3 InChI=1/C16H15N3O2/c1-16(12-8-4-2-5-9-12)14(20)19(15(21)17-16)18-13-10-6-3-7-11-13/h2-11,18H,1H3,(H,17,21)/t16-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Czech republic - CoRMS: France Fenamidone (Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fenamidone 22Feb2016 2016 doi:10.2903/j.efsa.2016.4406
+Fenamidone 605-252-0 161326-34-7 single chemical entity Component is a metabolite of the substance (S)-5-Methyl-5-phenyl-3-(phenylamino)- 2,4-imidazolidine-dione (5S)-5-methyl-5-phenyl-3-(phenylamino)imidazolidine-2,4-dione Not in list C16H15N3O2 O=C2N(Nc1ccccc1)C(=O)N[C@@]2(C)c3ccccc3 InChI=1/C16H15N3O2/c1-16(12-8-4-2-5-9-12)14(20)19(15(21)17-16)18-13-10-6-3-7-11-13/h2-11,18H,1H3,(H,17,21)/t16-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Czech republic - CoRMS: France Fenamidone (Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fenamidone 22Feb2016 2016 doi:10.2903/j.efsa.2016.4406
+Fenamidone 605-252-0 161326-34-7 single chemical entity Component is a metabolite of the substance (S)-5-Methyl-5-phenyl-3-(phenylamino)- 2,4-imidazolidine-dione (5S)-5-methyl-5-phenyl-3-(phenylamino)imidazolidine-2,4-dione Not in list C16H15N3O2 O=C2N(Nc1ccccc1)C(=O)N[C@@]2(C)c3ccccc3 InChI=1/C16H15N3O2/c1-16(12-8-4-2-5-9-12)14(20)19(15(21)17-16)18-13-10-6-3-7-11-13/h2-11,18H,1H3,(H,17,21)/t16-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Czech republic - CoRMS: France Fenamidone (Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fenamidone 22Feb2016 2016 doi:10.2903/j.efsa.2016.4406
+Fenamidone 605-252-0 161326-34-7 single chemical entity Component is a metabolite of the substance (S)-5-Methyl-5-phenyl-3-(phenylamino)- 2,4-imidazolidine-dione (5S)-5-methyl-5-phenyl-3-(phenylamino)imidazolidine-2,4-dione Not in list C16H15N3O2 O=C2N(Nc1ccccc1)C(=O)N[C@@]2(C)c3ccccc3 InChI=1/C16H15N3O2/c1-16(12-8-4-2-5-9-12)14(20)19(15(21)17-16)18-13-10-6-3-7-11-13/h2-11,18H,1H3,(H,17,21)/t16-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Czech republic - CoRMS: France Fenamidone (Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fenamidone 22Feb2016 2016 doi:10.2903/j.efsa.2016.4406
+Fenamidone 605-252-0 161326-34-7 single chemical entity Component is a metabolite of the substance (S)-5-Methyl-5-phenyl-3-(phenylamino)- 2,4-imidazolidine-dione (5S)-5-methyl-5-phenyl-3-(phenylamino)imidazolidine-2,4-dione Not in list C16H15N3O2 O=C2N(Nc1ccccc1)C(=O)N[C@@]2(C)c3ccccc3 InChI=1/C16H15N3O2/c1-16(12-8-4-2-5-9-12)14(20)19(15(21)17-16)18-13-10-6-3-7-11-13/h2-11,18H,1H3,(H,17,21)/t16-/m0/s1 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Czech republic - CoRMS: France Fenamidone (Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fenamidone 22Feb2016 2016 doi:10.2903/j.efsa.2016.4406
+Fenamidone 605-252-0 161326-34-7 single chemical entity Component is a metabolite of the substance (S)-5-Methyl-5-phenyl-3-(phenylamino)- 2,4-imidazolidine-dione (5S)-5-methyl-5-phenyl-3-(phenylamino)imidazolidine-2,4-dione Not in list C16H15N3O2 O=C2N(Nc1ccccc1)C(=O)N[C@@]2(C)c3ccccc3 InChI=1/C16H15N3O2/c1-16(12-8-4-2-5-9-12)14(20)19(15(21)17-16)18-13-10-6-3-7-11-13/h2-11,18H,1H3,(H,17,21)/t16-/m0/s1 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Czech republic - CoRMS: France Fenamidone (Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fenamidone 22Feb2016 2016 doi:10.2903/j.efsa.2016.4406
+Fenamidone 605-252-0 161326-34-7 single chemical entity Component is a metabolite of the substance (S)-5-Methyl-5-phenyl-3-(phenylamino)- 2,4-imidazolidine-dione (5S)-5-methyl-5-phenyl-3-(phenylamino)imidazolidine-2,4-dione Not in list C16H15N3O2 O=C2N(Nc1ccccc1)C(=O)N[C@@]2(C)c3ccccc3 InChI=1/C16H15N3O2/c1-16(12-8-4-2-5-9-12)14(20)19(15(21)17-16)18-13-10-6-3-7-11-13/h2-11,18H,1H3,(H,17,21)/t16-/m0/s1 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 8 Male intraperitoneal 24.0000000000 h yes not applicable Negative no evidence RMS: Czech republic - CoRMS: France Fenamidone (Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fenamidone 22Feb2016 2016 doi:10.2903/j.efsa.2016.4406
+Fenamidone 605-252-0 161326-34-7 single chemical entity Component is a metabolite of the substance (5S)-5-methyl-2-(methylthio)-5-phenyl-3,5-dihydro- 4H-imidazol-4-one (5S)-5-methyl-2-(methylsulfanyl)-5-phenyl-3,5-dihydro-4H-imidazol-4-one Not in list C11H12N2OS C[C@]1(N=C(SC)NC1=O)c2ccccc2 InChI=1/C11H12N2OS/c1-11(8-6-4-3-5-7-8)9(14)12-10(13-11)15-2/h3-7H,1-2H3,(H,12,13,14)/t11-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Czech republic - CoRMS: France Fenamidone (Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fenamidone 22Feb2016 2016 doi:10.2903/j.efsa.2016.4406
+Fenamidone 605-252-0 161326-34-7 single chemical entity Component is a metabolite of the substance (5S)-5-methyl-2-(methylthio)-5-phenyl-3,5-dihydro- 4H-imidazol-4-one (5S)-5-methyl-2-(methylsulfanyl)-5-phenyl-3,5-dihydro-4H-imidazol-4-one Not in list C11H12N2OS C[C@]1(N=C(SC)NC1=O)c2ccccc2 InChI=1/C11H12N2OS/c1-11(8-6-4-3-5-7-8)9(14)12-10(13-11)15-2/h3-7H,1-2H3,(H,12,13,14)/t11-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Czech republic - CoRMS: France Fenamidone (Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fenamidone 22Feb2016 2016 doi:10.2903/j.efsa.2016.4406
+Fenamidone 605-252-0 161326-34-7 single chemical entity Component is a metabolite of the substance (5S)-5-methyl-2-(methylthio)-5-phenyl-3,5-dihydro- 4H-imidazol-4-one (5S)-5-methyl-2-(methylsulfanyl)-5-phenyl-3,5-dihydro-4H-imidazol-4-one Not in list C11H12N2OS C[C@]1(N=C(SC)NC1=O)c2ccccc2 InChI=1/C11H12N2OS/c1-11(8-6-4-3-5-7-8)9(14)12-10(13-11)15-2/h3-7H,1-2H3,(H,12,13,14)/t11-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Czech republic - CoRMS: France Fenamidone (Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fenamidone 22Feb2016 2016 doi:10.2903/j.efsa.2016.4406
+Fenamidone 605-252-0 161326-34-7 single chemical entity Component is a metabolite of the substance (5S)-5-methyl-2-(methylthio)-5-phenyl-3,5-dihydro- 4H-imidazol-4-one (5S)-5-methyl-2-(methylsulfanyl)-5-phenyl-3,5-dihydro-4H-imidazol-4-one Not in list C11H12N2OS C[C@]1(N=C(SC)NC1=O)c2ccccc2 InChI=1/C11H12N2OS/c1-11(8-6-4-3-5-7-8)9(14)12-10(13-11)15-2/h3-7H,1-2H3,(H,12,13,14)/t11-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Czech republic - CoRMS: France Fenamidone (Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fenamidone 22Feb2016 2016 doi:10.2903/j.efsa.2016.4406
+Fenamidone 605-252-0 161326-34-7 single chemical entity Component is a metabolite of the substance (5S)-5-methyl-2-(methylthio)-5-phenyl-3,5-dihydro- 4H-imidazol-4-one (5S)-5-methyl-2-(methylsulfanyl)-5-phenyl-3,5-dihydro-4H-imidazol-4-one Not in list C11H12N2OS C[C@]1(N=C(SC)NC1=O)c2ccccc2 InChI=1/C11H12N2OS/c1-11(8-6-4-3-5-7-8)9(14)12-10(13-11)15-2/h3-7H,1-2H3,(H,12,13,14)/t11-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Czech republic - CoRMS: France Fenamidone (Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fenamidone 22Feb2016 2016 doi:10.2903/j.efsa.2016.4406
+Fenamidone 605-252-0 161326-34-7 single chemical entity Component is a metabolite of the substance (5S)-5-methyl-2-(methylthio)-5-phenyl-3,5-dihydro- 4H-imidazol-4-one (5S)-5-methyl-2-(methylsulfanyl)-5-phenyl-3,5-dihydro-4H-imidazol-4-one Not in list C11H12N2OS C[C@]1(N=C(SC)NC1=O)c2ccccc2 InChI=1/C11H12N2OS/c1-11(8-6-4-3-5-7-8)9(14)12-10(13-11)15-2/h3-7H,1-2H3,(H,12,13,14)/t11-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Czech republic - CoRMS: France Fenamidone (Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fenamidone 22Feb2016 2016 doi:10.2903/j.efsa.2016.4406
+Fenamidone 605-252-0 161326-34-7 single chemical entity Component is a metabolite of the substance (5S)-5-methyl-2-(methylthio)-5-phenyl-3,5-dihydro- 4H-imidazol-4-one (5S)-5-methyl-2-(methylsulfanyl)-5-phenyl-3,5-dihydro-4H-imidazol-4-one Not in list C11H12N2OS C[C@]1(N=C(SC)NC1=O)c2ccccc2 InChI=1/C11H12N2OS/c1-11(8-6-4-3-5-7-8)9(14)12-10(13-11)15-2/h3-7H,1-2H3,(H,12,13,14)/t11-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Czech republic - CoRMS: France Fenamidone (Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fenamidone 22Feb2016 2016 doi:10.2903/j.efsa.2016.4406
+Fenamidone 605-252-0 161326-34-7 single chemical entity Component is a metabolite of the substance (5S)-5-methyl-2-(methylthio)-5-phenyl-3,5-dihydro- 4H-imidazol-4-one (5S)-5-methyl-2-(methylsulfanyl)-5-phenyl-3,5-dihydro-4H-imidazol-4-one Not in list C11H12N2OS C[C@]1(N=C(SC)NC1=O)c2ccccc2 InChI=1/C11H12N2OS/c1-11(8-6-4-3-5-7-8)9(14)12-10(13-11)15-2/h3-7H,1-2H3,(H,12,13,14)/t11-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Czech republic - CoRMS: France Fenamidone (Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fenamidone 22Feb2016 2016 doi:10.2903/j.efsa.2016.4406
+Fenamidone 605-252-0 161326-34-7 single chemical entity Component is a metabolite of the substance (5S)-5-methyl-2-(methylthio)-5-phenyl-3,5-dihydro- 4H-imidazol-4-one (5S)-5-methyl-2-(methylsulfanyl)-5-phenyl-3,5-dihydro-4H-imidazol-4-one Not in list C11H12N2OS C[C@]1(N=C(SC)NC1=O)c2ccccc2 InChI=1/C11H12N2OS/c1-11(8-6-4-3-5-7-8)9(14)12-10(13-11)15-2/h3-7H,1-2H3,(H,12,13,14)/t11-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Czech republic - CoRMS: France Fenamidone (Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fenamidone 22Feb2016 2016 doi:10.2903/j.efsa.2016.4406
+Fenamidone 605-252-0 161326-34-7 single chemical entity Component is a metabolite of the substance (5S)-5-methyl-2-(methylthio)-5-phenyl-3,5-dihydro- 4H-imidazol-4-one (5S)-5-methyl-2-(methylsulfanyl)-5-phenyl-3,5-dihydro-4H-imidazol-4-one Not in list C11H12N2OS C[C@]1(N=C(SC)NC1=O)c2ccccc2 InChI=1/C11H12N2OS/c1-11(8-6-4-3-5-7-8)9(14)12-10(13-11)15-2/h3-7H,1-2H3,(H,12,13,14)/t11-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Czech republic - CoRMS: France Fenamidone (Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fenamidone 22Feb2016 2016 doi:10.2903/j.efsa.2016.4406
+Fenamidone 605-252-0 161326-34-7 single chemical entity Component is a metabolite of the substance (5S)-5-methyl-2-(methylthio)-5-phenyl-3,5-dihydro- 4H-imidazol-4-one (5S)-5-methyl-2-(methylsulfanyl)-5-phenyl-3,5-dihydro-4H-imidazol-4-one Not in list C11H12N2OS C[C@]1(N=C(SC)NC1=O)c2ccccc2 InChI=1/C11H12N2OS/c1-11(8-6-4-3-5-7-8)9(14)12-10(13-11)15-2/h3-7H,1-2H3,(H,12,13,14)/t11-/m0/s1 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 8 Male intraperitoneal 24.0000000000 h yes not applicable Negative direct evidence-cytotoxicity$indirect evidence-systemic toxicity RMS: Czech republic - CoRMS: France Fenamidone (Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fenamidone 22Feb2016 2016 doi:10.2903/j.efsa.2016.4406
+Fenoxycarb 276-696-7 72490-01-8 single chemical entity Component is identical to the substance Fenoxycarb 276-696-7 72490-01-8 ethyl [2-(4-phenoxyphenoxy)ethyl]carbamate Fenoxycarb C17H19NO4 O=C(NCCOC1=CC=C(OC2=CC=CC=C2)C=C1)OCC InChI=1S/C17H19NO4/c1-2-20-17(19)18-12-13-21-14-8-10-16(11-9-14)22-15-6-4-3-5-7-15/h3-11H,2,12-13H2,1H3,(H,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Fenoxycarb (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenoxycarb 14Dec2010 2010 doi:10.2903/j.efsa.2010.1779
+Fenoxycarb 276-696-7 72490-01-8 single chemical entity Component is identical to the substance Fenoxycarb 276-696-7 72490-01-8 ethyl [2-(4-phenoxyphenoxy)ethyl]carbamate Fenoxycarb C17H19NO4 O=C(NCCOC1=CC=C(OC2=CC=CC=C2)C=C1)OCC InChI=1S/C17H19NO4/c1-2-20-17(19)18-12-13-21-14-8-10-16(11-9-14)22-15-6-4-3-5-7-15/h3-11H,2,12-13H2,1H3,(H,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Fenoxycarb (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenoxycarb 14Dec2010 2010 doi:10.2903/j.efsa.2010.1779
+Fenoxycarb 276-696-7 72490-01-8 single chemical entity Component is identical to the substance Fenoxycarb 276-696-7 72490-01-8 ethyl [2-(4-phenoxyphenoxy)ethyl]carbamate Fenoxycarb C17H19NO4 O=C(NCCOC1=CC=C(OC2=CC=CC=C2)C=C1)OCC InChI=1S/C17H19NO4/c1-2-20-17(19)18-12-13-21-14-8-10-16(11-9-14)22-15-6-4-3-5-7-15/h3-11H,2,12-13H2,1H3,(H,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Fenoxycarb (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenoxycarb 14Dec2010 2010 doi:10.2903/j.efsa.2010.1779
+Fenoxycarb 276-696-7 72490-01-8 single chemical entity Component is identical to the substance Fenoxycarb 276-696-7 72490-01-8 ethyl [2-(4-phenoxyphenoxy)ethyl]carbamate Fenoxycarb C17H19NO4 O=C(NCCOC1=CC=C(OC2=CC=CC=C2)C=C1)OCC InChI=1S/C17H19NO4/c1-2-20-17(19)18-12-13-21-14-8-10-16(11-9-14)22-15-6-4-3-5-7-15/h3-11H,2,12-13H2,1H3,(H,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Fenoxycarb (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenoxycarb 14Dec2010 2010 doi:10.2903/j.efsa.2010.1779
+Fenoxycarb 276-696-7 72490-01-8 single chemical entity Component is identical to the substance Fenoxycarb 276-696-7 72490-01-8 ethyl [2-(4-phenoxyphenoxy)ethyl]carbamate Fenoxycarb C17H19NO4 O=C(NCCOC1=CC=C(OC2=CC=CC=C2)C=C1)OCC InChI=1S/C17H19NO4/c1-2-20-17(19)18-12-13-21-14-8-10-16(11-9-14)22-15-6-4-3-5-7-15/h3-11H,2,12-13H2,1H3,(H,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Fenoxycarb (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenoxycarb 14Dec2010 2010 doi:10.2903/j.efsa.2010.1779
+Fenoxycarb 276-696-7 72490-01-8 single chemical entity Component is identical to the substance Fenoxycarb 276-696-7 72490-01-8 ethyl [2-(4-phenoxyphenoxy)ethyl]carbamate Fenoxycarb C17H19NO4 O=C(NCCOC1=CC=C(OC2=CC=CC=C2)C=C1)OCC InChI=1S/C17H19NO4/c1-2-20-17(19)18-12-13-21-14-8-10-16(11-9-14)22-15-6-4-3-5-7-15/h3-11H,2,12-13H2,1H3,(H,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Fenoxycarb (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenoxycarb 14Dec2010 2010 doi:10.2903/j.efsa.2010.1779
+Fenoxycarb 276-696-7 72490-01-8 single chemical entity Component is identical to the substance Fenoxycarb 276-696-7 72490-01-8 ethyl [2-(4-phenoxyphenoxy)ethyl]carbamate Fenoxycarb C17H19NO4 O=C(NCCOC1=CC=C(OC2=CC=CC=C2)C=C1)OCC InChI=1S/C17H19NO4/c1-2-20-17(19)18-12-13-21-14-8-10-16(11-9-14)22-15-6-4-3-5-7-15/h3-11H,2,12-13H2,1H3,(H,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Fenoxycarb (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenoxycarb 14Dec2010 2010 doi:10.2903/j.efsa.2010.1779
+Fenoxycarb 276-696-7 72490-01-8 single chemical entity Component is identical to the substance Fenoxycarb 276-696-7 72490-01-8 ethyl [2-(4-phenoxyphenoxy)ethyl]carbamate Fenoxycarb C17H19NO4 O=C(NCCOC1=CC=C(OC2=CC=CC=C2)C=C1)OCC InChI=1S/C17H19NO4/c1-2-20-17(19)18-12-13-21-14-8-10-16(11-9-14)22-15-6-4-3-5-7-15/h3-11H,2,12-13H2,1H3,(H,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Fenoxycarb (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenoxycarb 14Dec2010 2010 doi:10.2903/j.efsa.2010.1779
+Fenoxycarb 276-696-7 72490-01-8 single chemical entity Component is identical to the substance Fenoxycarb 276-696-7 72490-01-8 ethyl [2-(4-phenoxyphenoxy)ethyl]carbamate Fenoxycarb C17H19NO4 O=C(NCCOC1=CC=C(OC2=CC=CC=C2)C=C1)OCC InChI=1S/C17H19NO4/c1-2-20-17(19)18-12-13-21-14-8-10-16(11-9-14)22-15-6-4-3-5-7-15/h3-11H,2,12-13H2,1H3,(H,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Fenoxycarb (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenoxycarb 14Dec2010 2010 doi:10.2903/j.efsa.2010.1779
+Fenoxycarb 276-696-7 72490-01-8 single chemical entity Component is identical to the substance Fenoxycarb 276-696-7 72490-01-8 ethyl [2-(4-phenoxyphenoxy)ethyl]carbamate Fenoxycarb C17H19NO4 O=C(NCCOC1=CC=C(OC2=CC=CC=C2)C=C1)OCC InChI=1S/C17H19NO4/c1-2-20-17(19)18-12-13-21-14-8-10-16(11-9-14)22-15-6-4-3-5-7-15/h3-11H,2,12-13H2,1H3,(H,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Fenoxycarb (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenoxycarb 14Dec2010 2010 doi:10.2903/j.efsa.2010.1779
+Fenoxycarb 276-696-7 72490-01-8 single chemical entity Component is identical to the substance Fenoxycarb 276-696-7 72490-01-8 ethyl [2-(4-phenoxyphenoxy)ethyl]carbamate Fenoxycarb C17H19NO4 O=C(NCCOC1=CC=C(OC2=CC=CC=C2)C=C1)OCC InChI=1S/C17H19NO4/c1-2-20-17(19)18-12-13-21-14-8-10-16(11-9-14)22-15-6-4-3-5-7-15/h3-11H,2,12-13H2,1H3,(H,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Fenoxycarb (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenoxycarb 14Dec2010 2010 doi:10.2903/j.efsa.2010.1779
+Fenoxycarb 276-696-7 72490-01-8 single chemical entity Component is identical to the substance Fenoxycarb 276-696-7 72490-01-8 ethyl [2-(4-phenoxyphenoxy)ethyl]carbamate Fenoxycarb C17H19NO4 O=C(NCCOC1=CC=C(OC2=CC=CC=C2)C=C1)OCC InChI=1S/C17H19NO4/c1-2-20-17(19)18-12-13-21-14-8-10-16(11-9-14)22-15-6-4-3-5-7-15/h3-11H,2,12-13H2,1H3,(H,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Fenoxycarb (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenoxycarb 14Dec2010 2010 doi:10.2903/j.efsa.2010.1779
+Fenoxycarb 276-696-7 72490-01-8 single chemical entity Component is identical to the substance Fenoxycarb 276-696-7 72490-01-8 ethyl [2-(4-phenoxyphenoxy)ethyl]carbamate Fenoxycarb C17H19NO4 O=C(NCCOC1=CC=C(OC2=CC=CC=C2)C=C1)OCC InChI=1S/C17H19NO4/c1-2-20-17(19)18-12-13-21-14-8-10-16(11-9-14)22-15-6-4-3-5-7-15/h3-11H,2,12-13H2,1H3,(H,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Fenoxycarb (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenoxycarb 14Dec2010 2010 doi:10.2903/j.efsa.2010.1779
+Fenoxycarb 276-696-7 72490-01-8 single chemical entity Component is identical to the substance Fenoxycarb 276-696-7 72490-01-8 ethyl [2-(4-phenoxyphenoxy)ethyl]carbamate Fenoxycarb C17H19NO4 O=C(NCCOC1=CC=C(OC2=CC=CC=C2)C=C1)OCC InChI=1S/C17H19NO4/c1-2-20-17(19)18-12-13-21-14-8-10-16(11-9-14)22-15-6-4-3-5-7-15/h3-11H,2,12-13H2,1H3,(H,18,19) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Fenoxycarb (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenoxycarb 14Dec2010 2010 doi:10.2903/j.efsa.2010.1779
+Fenoxycarb 276-696-7 72490-01-8 single chemical entity Component is identical to the substance Fenoxycarb 276-696-7 72490-01-8 ethyl [2-(4-phenoxyphenoxy)ethyl]carbamate Fenoxycarb C17H19NO4 O=C(NCCOC1=CC=C(OC2=CC=CC=C2)C=C1)OCC InChI=1S/C17H19NO4/c1-2-20-17(19)18-12-13-21-14-8-10-16(11-9-14)22-15-6-4-3-5-7-15/h3-11H,2,12-13H2,1H3,(H,18,19) organic compound Other Other genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro According to OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay) No Acceptable Saccharomyces cerevisiae (as organism) D7 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Fenoxycarb (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenoxycarb 14Dec2010 2010 doi:10.2903/j.efsa.2010.1779
+Fenoxycarb 276-696-7 72490-01-8 single chemical entity Component is identical to the substance Fenoxycarb 276-696-7 72490-01-8 ethyl [2-(4-phenoxyphenoxy)ethyl]carbamate Fenoxycarb C17H19NO4 O=C(NCCOC1=CC=C(OC2=CC=CC=C2)C=C1)OCC InChI=1S/C17H19NO4/c1-2-20-17(19)18-12-13-21-14-8-10-16(11-9-14)22-15-6-4-3-5-7-15/h3-11H,2,12-13H2,1H3,(H,18,19) organic compound Other Other genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro According to OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay) No Acceptable Saccharomyces cerevisiae (as organism) D7 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Fenoxycarb (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenoxycarb 14Dec2010 2010 doi:10.2903/j.efsa.2010.1779
+Fenoxycarb 276-696-7 72490-01-8 single chemical entity Component is identical to the substance Fenoxycarb 276-696-7 72490-01-8 ethyl [2-(4-phenoxyphenoxy)ethyl]carbamate Fenoxycarb C17H19NO4 O=C(NCCOC1=CC=C(OC2=CC=CC=C2)C=C1)OCC InChI=1S/C17H19NO4/c1-2-20-17(19)18-12-13-21-14-8-10-16(11-9-14)22-15-6-4-3-5-7-15/h3-11H,2,12-13H2,1H3,(H,18,19) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: The Netherlands Fenoxycarb (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenoxycarb 14Dec2010 2010 doi:10.2903/j.efsa.2010.1779
+Fenoxycarb 276-696-7 72490-01-8 single chemical entity Component is identical to the substance Fenoxycarb 276-696-7 72490-01-8 ethyl [2-(4-phenoxyphenoxy)ethyl]carbamate Fenoxycarb C17H19NO4 O=C(NCCOC1=CC=C(OC2=CC=CC=C2)C=C1)OCC InChI=1S/C17H19NO4/c1-2-20-17(19)18-12-13-21-14-8-10-16(11-9-14)22-15-6-4-3-5-7-15/h3-11H,2,12-13H2,1H3,(H,18,19) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: The Netherlands Fenoxycarb (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenoxycarb 14Dec2010 2010 doi:10.2903/j.efsa.2010.1779
+Fenoxycarb 276-696-7 72490-01-8 single chemical entity Component is identical to the substance Fenoxycarb 276-696-7 72490-01-8 ethyl [2-(4-phenoxyphenoxy)ethyl]carbamate Fenoxycarb C17H19NO4 O=C(NCCOC1=CC=C(OC2=CC=CC=C2)C=C1)OCC InChI=1S/C17H19NO4/c1-2-20-17(19)18-12-13-21-14-8-10-16(11-9-14)22-15-6-4-3-5-7-15/h3-11H,2,12-13H2,1H3,(H,18,19) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: The Netherlands Fenoxycarb (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenoxycarb 14Dec2010 2010 doi:10.2903/j.efsa.2010.1779
+Fenoxycarb 276-696-7 72490-01-8 single chemical entity Component is identical to the substance Fenoxycarb 276-696-7 72490-01-8 ethyl [2-(4-phenoxyphenoxy)ethyl]carbamate Fenoxycarb C17H19NO4 O=C(NCCOC1=CC=C(OC2=CC=CC=C2)C=C1)OCC InChI=1S/C17H19NO4/c1-2-20-17(19)18-12-13-21-14-8-10-16(11-9-14)22-15-6-4-3-5-7-15/h3-11H,2,12-13H2,1H3,(H,18,19) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: The Netherlands Fenoxycarb (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenoxycarb 14Dec2010 2010 doi:10.2903/j.efsa.2010.1779
+Fenoxycarb 276-696-7 72490-01-8 single chemical entity Component is identical to the substance Fenoxycarb 276-696-7 72490-01-8 ethyl [2-(4-phenoxyphenoxy)ethyl]carbamate Fenoxycarb C17H19NO4 O=C(NCCOC1=CC=C(OC2=CC=CC=C2)C=C1)OCC InChI=1S/C17H19NO4/c1-2-20-17(19)18-12-13-21-14-8-10-16(11-9-14)22-15-6-4-3-5-7-15/h3-11H,2,12-13H2,1H3,(H,18,19) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Tif:MAGf(SPF) 10 Male/Female oral: unspecified 24.0000000000 h yes not applicable Negative indirect-toxicokinetic investigations RMS: The Netherlands Fenoxycarb (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenoxycarb 14Dec2010 2010 doi:10.2903/j.efsa.2010.1779
+Fenoxycarb 276-696-7 72490-01-8 single chemical entity Component is identical to the substance Fenoxycarb 276-696-7 72490-01-8 ethyl [2-(4-phenoxyphenoxy)ethyl]carbamate Fenoxycarb C17H19NO4 O=C(NCCOC1=CC=C(OC2=CC=CC=C2)C=C1)OCC InChI=1S/C17H19NO4/c1-2-20-17(19)18-12-13-21-14-8-10-16(11-9-14)22-15-6-4-3-5-7-15/h3-11H,2,12-13H2,1H3,(H,18,19) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Tif:MAGf(SPF) 10 Male/Female oral: unspecified 48.0000000000 h yes not applicable Negative indirect-toxicokinetic investigations RMS: The Netherlands Fenoxycarb (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenoxycarb 14Dec2010 2010 doi:10.2903/j.efsa.2010.1779
+Fenoxycarb 276-696-7 72490-01-8 single chemical entity Component is identical to the substance Fenoxycarb 276-696-7 72490-01-8 ethyl [2-(4-phenoxyphenoxy)ethyl]carbamate Fenoxycarb C17H19NO4 O=C(NCCOC1=CC=C(OC2=CC=CC=C2)C=C1)OCC InChI=1S/C17H19NO4/c1-2-20-17(19)18-12-13-21-14-8-10-16(11-9-14)22-15-6-4-3-5-7-15/h3-11H,2,12-13H2,1H3,(H,18,19) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Tif:MAGf(SPF) 10 Male/Female oral: unspecified h yes not applicable Negative indirect-toxicokinetic investigations RMS: The Netherlands Fenoxycarb (Final Addendum) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenoxycarb 14Dec2010 2010 doi:10.2903/j.efsa.2010.1779
+Fenamiphos (aka phenamiphos) 244-848-1 22224-92-6 single chemical entity Component is identical to the substance Fenamiphos (aka phenamiphos) 244-848-1 22224-92-6 ethyl 3-methyl-4-(methylthio)phenyl isopropylamidophosphate Fenamiphos C13H22NO3PS Cc1cc(ccc1SC)OP(=O)(NC(C)C)OCC InChI=1S/C13H22NO3PS/c1-6-16-18(15,14-10(2)3)17-12-7-8-13(19-5)11(4)9-12/h7-10H,6H2,1-5H3,(H,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Fenamiphos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenamiphos 07Mar2006 2006 doi:10.2903/j.efsa.2006.62r
+Fenamiphos (aka phenamiphos) 244-848-1 22224-92-6 single chemical entity Component is identical to the substance Fenamiphos (aka phenamiphos) 244-848-1 22224-92-6 ethyl 3-methyl-4-(methylthio)phenyl isopropylamidophosphate Fenamiphos C13H22NO3PS Cc1cc(ccc1SC)OP(=O)(NC(C)C)OCC InChI=1S/C13H22NO3PS/c1-6-16-18(15,14-10(2)3)17-12-7-8-13(19-5)11(4)9-12/h7-10H,6H2,1-5H3,(H,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Fenamiphos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenamiphos 07Mar2006 2006 doi:10.2903/j.efsa.2006.62r
+Fenamiphos (aka phenamiphos) 244-848-1 22224-92-6 single chemical entity Component is identical to the substance Fenamiphos (aka phenamiphos) 244-848-1 22224-92-6 ethyl 3-methyl-4-(methylthio)phenyl isopropylamidophosphate Fenamiphos C13H22NO3PS Cc1cc(ccc1SC)OP(=O)(NC(C)C)OCC InChI=1S/C13H22NO3PS/c1-6-16-18(15,14-10(2)3)17-12-7-8-13(19-5)11(4)9-12/h7-10H,6H2,1-5H3,(H,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Fenamiphos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenamiphos 07Mar2006 2006 doi:10.2903/j.efsa.2006.62r
+Fenamiphos (aka phenamiphos) 244-848-1 22224-92-6 single chemical entity Component is identical to the substance Fenamiphos (aka phenamiphos) 244-848-1 22224-92-6 ethyl 3-methyl-4-(methylthio)phenyl isopropylamidophosphate Fenamiphos C13H22NO3PS Cc1cc(ccc1SC)OP(=O)(NC(C)C)OCC InChI=1S/C13H22NO3PS/c1-6-16-18(15,14-10(2)3)17-12-7-8-13(19-5)11(4)9-12/h7-10H,6H2,1-5H3,(H,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Fenamiphos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenamiphos 07Mar2006 2006 doi:10.2903/j.efsa.2006.62r
+Fenamiphos (aka phenamiphos) 244-848-1 22224-92-6 single chemical entity Component is identical to the substance Fenamiphos (aka phenamiphos) 244-848-1 22224-92-6 ethyl 3-methyl-4-(methylthio)phenyl isopropylamidophosphate Fenamiphos C13H22NO3PS Cc1cc(ccc1SC)OP(=O)(NC(C)C)OCC InChI=1S/C13H22NO3PS/c1-6-16-18(15,14-10(2)3)17-12-7-8-13(19-5)11(4)9-12/h7-10H,6H2,1-5H3,(H,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Fenamiphos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenamiphos 07Mar2006 2006 doi:10.2903/j.efsa.2006.62r
+Fenamiphos (aka phenamiphos) 244-848-1 22224-92-6 single chemical entity Component is identical to the substance Fenamiphos (aka phenamiphos) 244-848-1 22224-92-6 ethyl 3-methyl-4-(methylthio)phenyl isopropylamidophosphate Fenamiphos C13H22NO3PS Cc1cc(ccc1SC)OP(=O)(NC(C)C)OCC InChI=1S/C13H22NO3PS/c1-6-16-18(15,14-10(2)3)17-12-7-8-13(19-5)11(4)9-12/h7-10H,6H2,1-5H3,(H,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Fenamiphos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenamiphos 07Mar2006 2006 doi:10.2903/j.efsa.2006.62r
+Fenamiphos (aka phenamiphos) 244-848-1 22224-92-6 single chemical entity Component is identical to the substance Fenamiphos (aka phenamiphos) 244-848-1 22224-92-6 ethyl 3-methyl-4-(methylthio)phenyl isopropylamidophosphate Fenamiphos C13H22NO3PS Cc1cc(ccc1SC)OP(=O)(NC(C)C)OCC InChI=1S/C13H22NO3PS/c1-6-16-18(15,14-10(2)3)17-12-7-8-13(19-5)11(4)9-12/h7-10H,6H2,1-5H3,(H,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Fenamiphos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenamiphos 07Mar2006 2006 doi:10.2903/j.efsa.2006.62r
+Fenamiphos (aka phenamiphos) 244-848-1 22224-92-6 single chemical entity Component is identical to the substance Fenamiphos (aka phenamiphos) 244-848-1 22224-92-6 ethyl 3-methyl-4-(methylthio)phenyl isopropylamidophosphate Fenamiphos C13H22NO3PS Cc1cc(ccc1SC)OP(=O)(NC(C)C)OCC InChI=1S/C13H22NO3PS/c1-6-16-18(15,14-10(2)3)17-12-7-8-13(19-5)11(4)9-12/h7-10H,6H2,1-5H3,(H,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Fenamiphos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenamiphos 07Mar2006 2006 doi:10.2903/j.efsa.2006.62r
+Fenamiphos (aka phenamiphos) 244-848-1 22224-92-6 single chemical entity Component is identical to the substance Fenamiphos (aka phenamiphos) 244-848-1 22224-92-6 ethyl 3-methyl-4-(methylthio)phenyl isopropylamidophosphate Fenamiphos C13H22NO3PS Cc1cc(ccc1SC)OP(=O)(NC(C)C)OCC InChI=1S/C13H22NO3PS/c1-6-16-18(15,14-10(2)3)17-12-7-8-13(19-5)11(4)9-12/h7-10H,6H2,1-5H3,(H,14,15) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Fenamiphos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenamiphos 07Mar2006 2006 doi:10.2903/j.efsa.2006.62r
+Fenamiphos (aka phenamiphos) 244-848-1 22224-92-6 single chemical entity Component is identical to the substance Fenamiphos (aka phenamiphos) 244-848-1 22224-92-6 ethyl 3-methyl-4-(methylthio)phenyl isopropylamidophosphate Fenamiphos C13H22NO3PS Cc1cc(ccc1SC)OP(=O)(NC(C)C)OCC InChI=1S/C13H22NO3PS/c1-6-16-18(15,14-10(2)3)17-12-7-8-13(19-5)11(4)9-12/h7-10H,6H2,1-5H3,(H,14,15) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Fenamiphos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenamiphos 07Mar2006 2006 doi:10.2903/j.efsa.2006.62r
+Fenamiphos (aka phenamiphos) 244-848-1 22224-92-6 single chemical entity Component is identical to the substance Fenamiphos (aka phenamiphos) 244-848-1 22224-92-6 ethyl 3-methyl-4-(methylthio)phenyl isopropylamidophosphate Fenamiphos C13H22NO3PS Cc1cc(ccc1SC)OP(=O)(NC(C)C)OCC InChI=1S/C13H22NO3PS/c1-6-16-18(15,14-10(2)3)17-12-7-8-13(19-5)11(4)9-12/h7-10H,6H2,1-5H3,(H,14,15) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes without Positive RMS: The Netherlands Fenamiphos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenamiphos 07Mar2006 2006 doi:10.2903/j.efsa.2006.62r
+Fenamiphos (aka phenamiphos) 244-848-1 22224-92-6 single chemical entity Component is identical to the substance Fenamiphos (aka phenamiphos) 244-848-1 22224-92-6 ethyl 3-methyl-4-(methylthio)phenyl isopropylamidophosphate Fenamiphos C13H22NO3PS Cc1cc(ccc1SC)OP(=O)(NC(C)C)OCC InChI=1S/C13H22NO3PS/c1-6-16-18(15,14-10(2)3)17-12-7-8-13(19-5)11(4)9-12/h7-10H,6H2,1-5H3,(H,14,15) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Positive RMS: The Netherlands Fenamiphos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenamiphos 07Mar2006 2006 doi:10.2903/j.efsa.2006.62r
+Fenamiphos (aka phenamiphos) 244-848-1 22224-92-6 single chemical entity Component is identical to the substance Fenamiphos (aka phenamiphos) 244-848-1 22224-92-6 ethyl 3-methyl-4-(methylthio)phenyl isopropylamidophosphate Fenamiphos C13H22NO3PS Cc1cc(ccc1SC)OP(=O)(NC(C)C)OCC InChI=1S/C13H22NO3PS/c1-6-16-18(15,14-10(2)3)17-12-7-8-13(19-5)11(4)9-12/h7-10H,6H2,1-5H3,(H,14,15) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Fenamiphos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenamiphos 07Mar2006 2006 doi:10.2903/j.efsa.2006.62r
+Fenamiphos (aka phenamiphos) 244-848-1 22224-92-6 single chemical entity Component is identical to the substance Fenamiphos (aka phenamiphos) 244-848-1 22224-92-6 ethyl 3-methyl-4-(methylthio)phenyl isopropylamidophosphate Fenamiphos C13H22NO3PS Cc1cc(ccc1SC)OP(=O)(NC(C)C)OCC InChI=1S/C13H22NO3PS/c1-6-16-18(15,14-10(2)3)17-12-7-8-13(19-5)11(4)9-12/h7-10H,6H2,1-5H3,(H,14,15) organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Fenamiphos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenamiphos 07Mar2006 2006 doi:10.2903/j.efsa.2006.62r
+Fenamiphos (aka phenamiphos) 244-848-1 22224-92-6 single chemical entity Component is identical to the substance Fenamiphos (aka phenamiphos) 244-848-1 22224-92-6 ethyl 3-methyl-4-(methylthio)phenyl isopropylamidophosphate Fenamiphos C13H22NO3PS Cc1cc(ccc1SC)OP(=O)(NC(C)C)OCC InChI=1S/C13H22NO3PS/c1-6-16-18(15,14-10(2)3)17-12-7-8-13(19-5)11(4)9-12/h7-10H,6H2,1-5H3,(H,14,15) organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Fenamiphos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenamiphos 07Mar2006 2006 doi:10.2903/j.efsa.2006.62r
+Fenamiphos (aka phenamiphos) 244-848-1 22224-92-6 single chemical entity Component is identical to the substance Fenamiphos (aka phenamiphos) 244-848-1 22224-92-6 ethyl 3-methyl-4-(methylthio)phenyl isopropylamidophosphate Fenamiphos C13H22NO3PS Cc1cc(ccc1SC)OP(=O)(NC(C)C)OCC InChI=1S/C13H22NO3PS/c1-6-16-18(15,14-10(2)3)17-12-7-8-13(19-5)11(4)9-12/h7-10H,6H2,1-5H3,(H,14,15) organic compound Other Other chromosome aberration dominant lethal assay in vivo According to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) No Acceptable House mouse (as animal) NMRI 50 Male oral: unspecified 20.0000000000 D no data not applicable Negative RMS: The Netherlands Fenamiphos 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenamiphos 07Mar2006 2006 doi:10.2903/j.efsa.2006.62r
+Fenamiphos (aka phenamiphos) 244-848-1 22224-92-6 single chemical entity Component is identical to the substance Fenamiphos (aka phenamiphos) 244-848-1 22224-92-6 ethyl 3-methyl-4-(methylthio)phenyl isopropylamidophosphate Fenamiphos C13H22NO3PS Cc1cc(ccc1SC)OP(=O)(NC(C)C)OCC InChI=1S/C13H22NO3PS/c1-6-16-18(15,14-10(2)3)17-12-7-8-13(19-5)11(4)9-12/h7-10H,6H2,1-5H3,(H,14,15) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: The Netherlands Fenamiphos (Final Addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenamiphos 07Mar2006 2006 doi:10.2903/j.efsa.2006.62r
+Fenamiphos (aka phenamiphos) 244-848-1 22224-92-6 single chemical entity Component is identical to the substance Fenamiphos (aka phenamiphos) 244-848-1 22224-92-6 ethyl 3-methyl-4-(methylthio)phenyl isopropylamidophosphate Fenamiphos C13H22NO3PS Cc1cc(ccc1SC)OP(=O)(NC(C)C)OCC InChI=1S/C13H22NO3PS/c1-6-16-18(15,14-10(2)3)17-12-7-8-13(19-5)11(4)9-12/h7-10H,6H2,1-5H3,(H,14,15) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: The Netherlands Fenamiphos (Final Addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenamiphos 07Mar2006 2006 doi:10.2903/j.efsa.2006.62r
+Fenamiphos (aka phenamiphos) 244-848-1 22224-92-6 single chemical entity Component is identical to the substance Fenamiphos (aka phenamiphos) 244-848-1 22224-92-6 ethyl 3-methyl-4-(methylthio)phenyl isopropylamidophosphate Fenamiphos C13H22NO3PS Cc1cc(ccc1SC)OP(=O)(NC(C)C)OCC InChI=1S/C13H22NO3PS/c1-6-16-18(15,14-10(2)3)17-12-7-8-13(19-5)11(4)9-12/h7-10H,6H2,1-5H3,(H,14,15) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Not reported 5 Male/Female intraperitoneal 48.0000000000 h yes not applicable Negative indirect evidence-systemic toxicity RMS: The Netherlands Fenamiphos (Final Addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenamiphos 07Mar2006 2006 doi:10.2903/j.efsa.2006.62r
+Fenamiphos (aka phenamiphos) 244-848-1 22224-92-6 single chemical entity Component is identical to the substance Fenamiphos (aka phenamiphos) 244-848-1 22224-92-6 ethyl 3-methyl-4-(methylthio)phenyl isopropylamidophosphate Fenamiphos C13H22NO3PS Cc1cc(ccc1SC)OP(=O)(NC(C)C)OCC InChI=1S/C13H22NO3PS/c1-6-16-18(15,14-10(2)3)17-12-7-8-13(19-5)11(4)9-12/h7-10H,6H2,1-5H3,(H,14,15) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Not reported 5 Male/Female intraperitoneal 16.0000000000 h yes not applicable Negative no evidence RMS: The Netherlands Fenamiphos (Final Addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenamiphos 07Mar2006 2006 doi:10.2903/j.efsa.2006.62r
+Fenamiphos (aka phenamiphos) 244-848-1 22224-92-6 single chemical entity Component is identical to the substance Fenamiphos (aka phenamiphos) 244-848-1 22224-92-6 ethyl 3-methyl-4-(methylthio)phenyl isopropylamidophosphate Fenamiphos C13H22NO3PS Cc1cc(ccc1SC)OP(=O)(NC(C)C)OCC InChI=1S/C13H22NO3PS/c1-6-16-18(15,14-10(2)3)17-12-7-8-13(19-5)11(4)9-12/h7-10H,6H2,1-5H3,(H,14,15) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Not reported 5 Male/Female intraperitoneal 24.0000000000 h yes not applicable Negative indirect evidence-systemic toxicity RMS: The Netherlands Fenamiphos (Final Addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenamiphos 07Mar2006 2006 doi:10.2903/j.efsa.2006.62r
+Fenamiphos (aka phenamiphos) 244-848-1 22224-92-6 single chemical entity Component is a metabolite of the substance des-isopropylamino fenamiphos sulfoxide Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Fenamiphos (Final Addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenamiphos 07Mar2006 2006 doi:10.2903/j.efsa.2006.62r
+Fenamiphos (aka phenamiphos) 244-848-1 22224-92-6 single chemical entity Component is a metabolite of the substance des-isopropylamino fenamiphos sulfoxide Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Fenamiphos (Final Addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenamiphos 07Mar2006 2006 doi:10.2903/j.efsa.2006.62r
+Fenamiphos (aka phenamiphos) 244-848-1 22224-92-6 single chemical entity Component is a metabolite of the substance des-isopropylamino fenamiphos sulfoxide Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Fenamiphos (Final Addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenamiphos 07Mar2006 2006 doi:10.2903/j.efsa.2006.62r
+Fenamiphos (aka phenamiphos) 244-848-1 22224-92-6 single chemical entity Component is a metabolite of the substance des-isopropylamino fenamiphos sulfoxide Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Fenamiphos (Final Addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenamiphos 07Mar2006 2006 doi:10.2903/j.efsa.2006.62r
+Fenamiphos (aka phenamiphos) 244-848-1 22224-92-6 single chemical entity Component is a metabolite of the substance des-isopropylamino fenamiphos sulfoxide Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Fenamiphos (Final Addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenamiphos 07Mar2006 2006 doi:10.2903/j.efsa.2006.62r
+Fenamiphos (aka phenamiphos) 244-848-1 22224-92-6 single chemical entity Component is a metabolite of the substance des-isopropylamino fenamiphos sulfoxide Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Fenamiphos (Final Addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenamiphos 07Mar2006 2006 doi:10.2903/j.efsa.2006.62r
+Fenamiphos (aka phenamiphos) 244-848-1 22224-92-6 single chemical entity Component is a metabolite of the substance des-isopropylamino fenamiphos sulfoxide Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Fenamiphos (Final Addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenamiphos 07Mar2006 2006 doi:10.2903/j.efsa.2006.62r
+Fenamiphos (aka phenamiphos) 244-848-1 22224-92-6 single chemical entity Component is a metabolite of the substance des-isopropylamino fenamiphos sulfoxide Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The Netherlands Fenamiphos (Final Addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenamiphos 07Mar2006 2006 doi:10.2903/j.efsa.2006.62r
+Fenamiphos (aka phenamiphos) 244-848-1 22224-92-6 single chemical entity Component is a metabolite of the substance des-isopropylamino fenamiphos sulfoxide Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Fenamiphos (Final Addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenamiphos 07Mar2006 2006 doi:10.2903/j.efsa.2006.62r
+Fenamiphos (aka phenamiphos) 244-848-1 22224-92-6 single chemical entity Component is a metabolite of the substance des-isopropylamino fenamiphos sulfoxide Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The Netherlands Fenamiphos (Final Addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenamiphos 07Mar2006 2006 doi:10.2903/j.efsa.2006.62r
+Fenbutatin oxide 236-407-7 13356-08-6 single chemical entity Component is identical to the substance Fenbutatin oxide 236-407-7 13356-08-6 hexakis(2-methyl-2-phenylpropyl)distannoxane Fenbutatin oxide C60H78OSn2 CC(C)(C[Sn](CC(C)(C)c1ccccc1)(CC(C)(C)c2ccccc2)O[Sn](CC(C)(C)c3ccccc3)(CC(C)(C)c4ccccc4)CC(C)(C)c5ccccc5)c6ccccc6 InChI=1/6C10H13.O.2Sn/c6*1-10(2,3)9-7-5-4-6-8-9;;;/h6*4-8H,1H2,2-3H3;;;/rC60H78OSn2/c1-55(2,49-31-19-13-20-32-49)43-62(44-56(3,4)50-33-21-14-22-34-50,45-57(5,6)51-35-23-15-24-36-51)61-63(46-58(7,8)52-37-25-16-26-38-52,47-59(9,10)53-39-27-17-28-40-53)48-60 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Belgium Fenbutatin oxide 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbutatin oxide. 01Sep2010 2010 doi:10.2903/j.efsa.2010.1711
+Fenbutatin oxide 236-407-7 13356-08-6 single chemical entity Component is identical to the substance Fenbutatin oxide 236-407-7 13356-08-6 hexakis(2-methyl-2-phenylpropyl)distannoxane Fenbutatin oxide C60H78OSn2 CC(C)(C[Sn](CC(C)(C)c1ccccc1)(CC(C)(C)c2ccccc2)O[Sn](CC(C)(C)c3ccccc3)(CC(C)(C)c4ccccc4)CC(C)(C)c5ccccc5)c6ccccc6 InChI=1/6C10H13.O.2Sn/c6*1-10(2,3)9-7-5-4-6-8-9;;;/h6*4-8H,1H2,2-3H3;;;/rC60H78OSn2/c1-55(2,49-31-19-13-20-32-49)43-62(44-56(3,4)50-33-21-14-22-34-50,45-57(5,6)51-35-23-15-24-36-51)61-63(46-58(7,8)52-37-25-16-26-38-52,47-59(9,10)53-39-27-17-28-40-53)48-60 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Belgium Fenbutatin oxide 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbutatin oxide. 01Sep2010 2010 doi:10.2903/j.efsa.2010.1711
+Fenbutatin oxide 236-407-7 13356-08-6 single chemical entity Component is identical to the substance Fenbutatin oxide 236-407-7 13356-08-6 hexakis(2-methyl-2-phenylpropyl)distannoxane Fenbutatin oxide C60H78OSn2 CC(C)(C[Sn](CC(C)(C)c1ccccc1)(CC(C)(C)c2ccccc2)O[Sn](CC(C)(C)c3ccccc3)(CC(C)(C)c4ccccc4)CC(C)(C)c5ccccc5)c6ccccc6 InChI=1/6C10H13.O.2Sn/c6*1-10(2,3)9-7-5-4-6-8-9;;;/h6*4-8H,1H2,2-3H3;;;/rC60H78OSn2/c1-55(2,49-31-19-13-20-32-49)43-62(44-56(3,4)50-33-21-14-22-34-50,45-57(5,6)51-35-23-15-24-36-51)61-63(46-58(7,8)52-37-25-16-26-38-52,47-59(9,10)53-39-27-17-28-40-53)48-60 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Belgium Fenbutatin oxide 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbutatin oxide. 01Sep2010 2010 doi:10.2903/j.efsa.2010.1711
+Fenbutatin oxide 236-407-7 13356-08-6 single chemical entity Component is identical to the substance Fenbutatin oxide 236-407-7 13356-08-6 hexakis(2-methyl-2-phenylpropyl)distannoxane Fenbutatin oxide C60H78OSn2 CC(C)(C[Sn](CC(C)(C)c1ccccc1)(CC(C)(C)c2ccccc2)O[Sn](CC(C)(C)c3ccccc3)(CC(C)(C)c4ccccc4)CC(C)(C)c5ccccc5)c6ccccc6 InChI=1/6C10H13.O.2Sn/c6*1-10(2,3)9-7-5-4-6-8-9;;;/h6*4-8H,1H2,2-3H3;;;/rC60H78OSn2/c1-55(2,49-31-19-13-20-32-49)43-62(44-56(3,4)50-33-21-14-22-34-50,45-57(5,6)51-35-23-15-24-36-51)61-63(46-58(7,8)52-37-25-16-26-38-52,47-59(9,10)53-39-27-17-28-40-53)48-60 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Belgium Fenbutatin oxide 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbutatin oxide. 01Sep2010 2010 doi:10.2903/j.efsa.2010.1711
+Fenbutatin oxide 236-407-7 13356-08-6 single chemical entity Component is identical to the substance Fenbutatin oxide 236-407-7 13356-08-6 hexakis(2-methyl-2-phenylpropyl)distannoxane Fenbutatin oxide C60H78OSn2 CC(C)(C[Sn](CC(C)(C)c1ccccc1)(CC(C)(C)c2ccccc2)O[Sn](CC(C)(C)c3ccccc3)(CC(C)(C)c4ccccc4)CC(C)(C)c5ccccc5)c6ccccc6 InChI=1/6C10H13.O.2Sn/c6*1-10(2,3)9-7-5-4-6-8-9;;;/h6*4-8H,1H2,2-3H3;;;/rC60H78OSn2/c1-55(2,49-31-19-13-20-32-49)43-62(44-56(3,4)50-33-21-14-22-34-50,45-57(5,6)51-35-23-15-24-36-51)61-63(46-58(7,8)52-37-25-16-26-38-52,47-59(9,10)53-39-27-17-28-40-53)48-60 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Belgium Fenbutatin oxide 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbutatin oxide. 01Sep2010 2010 doi:10.2903/j.efsa.2010.1711
+Fenbutatin oxide 236-407-7 13356-08-6 single chemical entity Component is identical to the substance Fenbutatin oxide 236-407-7 13356-08-6 hexakis(2-methyl-2-phenylpropyl)distannoxane Fenbutatin oxide C60H78OSn2 CC(C)(C[Sn](CC(C)(C)c1ccccc1)(CC(C)(C)c2ccccc2)O[Sn](CC(C)(C)c3ccccc3)(CC(C)(C)c4ccccc4)CC(C)(C)c5ccccc5)c6ccccc6 InChI=1/6C10H13.O.2Sn/c6*1-10(2,3)9-7-5-4-6-8-9;;;/h6*4-8H,1H2,2-3H3;;;/rC60H78OSn2/c1-55(2,49-31-19-13-20-32-49)43-62(44-56(3,4)50-33-21-14-22-34-50,45-57(5,6)51-35-23-15-24-36-51)61-63(46-58(7,8)52-37-25-16-26-38-52,47-59(9,10)53-39-27-17-28-40-53)48-60 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Belgium Fenbutatin oxide 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbutatin oxide. 01Sep2010 2010 doi:10.2903/j.efsa.2010.1711
+Fenbutatin oxide 236-407-7 13356-08-6 single chemical entity Component is identical to the substance Fenbutatin oxide 236-407-7 13356-08-6 hexakis(2-methyl-2-phenylpropyl)distannoxane Fenbutatin oxide C60H78OSn2 CC(C)(C[Sn](CC(C)(C)c1ccccc1)(CC(C)(C)c2ccccc2)O[Sn](CC(C)(C)c3ccccc3)(CC(C)(C)c4ccccc4)CC(C)(C)c5ccccc5)c6ccccc6 InChI=1/6C10H13.O.2Sn/c6*1-10(2,3)9-7-5-4-6-8-9;;;/h6*4-8H,1H2,2-3H3;;;/rC60H78OSn2/c1-55(2,49-31-19-13-20-32-49)43-62(44-56(3,4)50-33-21-14-22-34-50,45-57(5,6)51-35-23-15-24-36-51)61-63(46-58(7,8)52-37-25-16-26-38-52,47-59(9,10)53-39-27-17-28-40-53)48-60 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle with Negative RMS: Belgium Fenbutatin oxide 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbutatin oxide. 01Sep2010 2010 doi:10.2903/j.efsa.2010.1711
+Fenbutatin oxide 236-407-7 13356-08-6 single chemical entity Component is identical to the substance Fenbutatin oxide 236-407-7 13356-08-6 hexakis(2-methyl-2-phenylpropyl)distannoxane Fenbutatin oxide C60H78OSn2 CC(C)(C[Sn](CC(C)(C)c1ccccc1)(CC(C)(C)c2ccccc2)O[Sn](CC(C)(C)c3ccccc3)(CC(C)(C)c4ccccc4)CC(C)(C)c5ccccc5)c6ccccc6 InChI=1/6C10H13.O.2Sn/c6*1-10(2,3)9-7-5-4-6-8-9;;;/h6*4-8H,1H2,2-3H3;;;/rC60H78OSn2/c1-55(2,49-31-19-13-20-32-49)43-62(44-56(3,4)50-33-21-14-22-34-50,45-57(5,6)51-35-23-15-24-36-51)61-63(46-58(7,8)52-37-25-16-26-38-52,47-59(9,10)53-39-27-17-28-40-53)48-60 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle without Negative RMS: Belgium Fenbutatin oxide 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbutatin oxide. 01Sep2010 2010 doi:10.2903/j.efsa.2010.1711
+Fenbutatin oxide 236-407-7 13356-08-6 single chemical entity Component is identical to the substance Fenbutatin oxide 236-407-7 13356-08-6 hexakis(2-methyl-2-phenylpropyl)distannoxane Fenbutatin oxide C60H78OSn2 CC(C)(C[Sn](CC(C)(C)c1ccccc1)(CC(C)(C)c2ccccc2)O[Sn](CC(C)(C)c3ccccc3)(CC(C)(C)c4ccccc4)CC(C)(C)c5ccccc5)c6ccccc6 InChI=1/6C10H13.O.2Sn/c6*1-10(2,3)9-7-5-4-6-8-9;;;/h6*4-8H,1H2,2-3H3;;;/rC60H78OSn2/c1-55(2,49-31-19-13-20-32-49)43-62(44-56(3,4)50-33-21-14-22-34-50,45-57(5,6)51-35-23-15-24-36-51)61-63(46-58(7,8)52-37-25-16-26-38-52,47-59(9,10)53-39-27-17-28-40-53)48-60 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro No guideline available Not reported Not applicable Acceptable Other Alpha 742 S. marcescens Not reported yes without Negative RMS: Belgium Fenbutatin oxide 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbutatin oxide. 01Sep2010 2010 doi:10.2903/j.efsa.2010.1711
+Fenbutatin oxide 236-407-7 13356-08-6 single chemical entity Component is identical to the substance Fenbutatin oxide 236-407-7 13356-08-6 hexakis(2-methyl-2-phenylpropyl)distannoxane Fenbutatin oxide C60H78OSn2 CC(C)(C[Sn](CC(C)(C)c1ccccc1)(CC(C)(C)c2ccccc2)O[Sn](CC(C)(C)c3ccccc3)(CC(C)(C)c4ccccc4)CC(C)(C)c5ccccc5)c6ccccc6 InChI=1/6C10H13.O.2Sn/c6*1-10(2,3)9-7-5-4-6-8-9;;;/h6*4-8H,1H2,2-3H3;;;/rC60H78OSn2/c1-55(2,49-31-19-13-20-32-49)43-62(44-56(3,4)50-33-21-14-22-34-50,45-57(5,6)51-35-23-15-24-36-51)61-63(46-58(7,8)52-37-25-16-26-38-52,47-59(9,10)53-39-27-17-28-40-53)48-60 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro No guideline available Not reported Not applicable Acceptable Other Alpha 21 S. marcescens Not reported yes without Negative RMS: Belgium Fenbutatin oxide 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbutatin oxide. 01Sep2010 2010 doi:10.2903/j.efsa.2010.1711
+Fenbutatin oxide 236-407-7 13356-08-6 single chemical entity Component is identical to the substance Fenbutatin oxide 236-407-7 13356-08-6 hexakis(2-methyl-2-phenylpropyl)distannoxane Fenbutatin oxide C60H78OSn2 CC(C)(C[Sn](CC(C)(C)c1ccccc1)(CC(C)(C)c2ccccc2)O[Sn](CC(C)(C)c3ccccc3)(CC(C)(C)c4ccccc4)CC(C)(C)c5ccccc5)c6ccccc6 InChI=1/6C10H13.O.2Sn/c6*1-10(2,3)9-7-5-4-6-8-9;;;/h6*4-8H,1H2,2-3H3;;;/rC60H78OSn2/c1-55(2,49-31-19-13-20-32-49)43-62(44-56(3,4)50-33-21-14-22-34-50,45-57(5,6)51-35-23-15-24-36-51)61-63(46-58(7,8)52-37-25-16-26-38-52,47-59(9,10)53-39-27-17-28-40-53)48-60 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro No guideline available Not reported Not applicable Acceptable Other Alpha 13 S. marcescens Not reported yes without Negative RMS: Belgium Fenbutatin oxide 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbutatin oxide. 01Sep2010 2010 doi:10.2903/j.efsa.2010.1711
+Fenbutatin oxide 236-407-7 13356-08-6 single chemical entity Component is identical to the substance Fenbutatin oxide 236-407-7 13356-08-6 hexakis(2-methyl-2-phenylpropyl)distannoxane Fenbutatin oxide C60H78OSn2 CC(C)(C[Sn](CC(C)(C)c1ccccc1)(CC(C)(C)c2ccccc2)O[Sn](CC(C)(C)c3ccccc3)(CC(C)(C)c4ccccc4)CC(C)(C)c5ccccc5)c6ccccc6 InChI=1/6C10H13.O.2Sn/c6*1-10(2,3)9-7-5-4-6-8-9;;;/h6*4-8H,1H2,2-3H3;;;/rC60H78OSn2/c1-55(2,49-31-19-13-20-32-49)43-62(44-56(3,4)50-33-21-14-22-34-50,45-57(5,6)51-35-23-15-24-36-51)61-63(46-58(7,8)52-37-25-16-26-38-52,47-59(9,10)53-39-27-17-28-40-53)48-60 organic compound Other Other gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Saccharomyces cerevisiae (as organism) D4 Not reported yes without Negative RMS: Belgium Fenbutatin oxide 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbutatin oxide. 01Sep2010 2010 doi:10.2903/j.efsa.2010.1711
+Fenbutatin oxide 236-407-7 13356-08-6 single chemical entity Component is identical to the substance Fenbutatin oxide 236-407-7 13356-08-6 hexakis(2-methyl-2-phenylpropyl)distannoxane Fenbutatin oxide C60H78OSn2 CC(C)(C[Sn](CC(C)(C)c1ccccc1)(CC(C)(C)c2ccccc2)O[Sn](CC(C)(C)c3ccccc3)(CC(C)(C)c4ccccc4)CC(C)(C)c5ccccc5)c6ccccc6 InChI=1/6C10H13.O.2Sn/c6*1-10(2,3)9-7-5-4-6-8-9;;;/h6*4-8H,1H2,2-3H3;;;/rC60H78OSn2/c1-55(2,49-31-19-13-20-32-49)43-62(44-56(3,4)50-33-21-14-22-34-50,45-57(5,6)51-35-23-15-24-36-51)61-63(46-58(7,8)52-37-25-16-26-38-52,47-59(9,10)53-39-27-17-28-40-53)48-60 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: Belgium Fenbutatin oxide 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbutatin oxide. 01Sep2010 2010 doi:10.2903/j.efsa.2010.1711
+Fenbutatin oxide 236-407-7 13356-08-6 single chemical entity Component is identical to the substance Fenbutatin oxide 236-407-7 13356-08-6 hexakis(2-methyl-2-phenylpropyl)distannoxane Fenbutatin oxide C60H78OSn2 CC(C)(C[Sn](CC(C)(C)c1ccccc1)(CC(C)(C)c2ccccc2)O[Sn](CC(C)(C)c3ccccc3)(CC(C)(C)c4ccccc4)CC(C)(C)c5ccccc5)c6ccccc6 InChI=1/6C10H13.O.2Sn/c6*1-10(2,3)9-7-5-4-6-8-9;;;/h6*4-8H,1H2,2-3H3;;;/rC60H78OSn2/c1-55(2,49-31-19-13-20-32-49)43-62(44-56(3,4)50-33-21-14-22-34-50,45-57(5,6)51-35-23-15-24-36-51)61-63(46-58(7,8)52-37-25-16-26-38-52,47-59(9,10)53-39-27-17-28-40-53)48-60 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: Belgium Fenbutatin oxide 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbutatin oxide. 01Sep2010 2010 doi:10.2903/j.efsa.2010.1711
+Fenbutatin oxide 236-407-7 13356-08-6 single chemical entity Component is identical to the substance Fenbutatin oxide 236-407-7 13356-08-6 hexakis(2-methyl-2-phenylpropyl)distannoxane Fenbutatin oxide C60H78OSn2 CC(C)(C[Sn](CC(C)(C)c1ccccc1)(CC(C)(C)c2ccccc2)O[Sn](CC(C)(C)c3ccccc3)(CC(C)(C)c4ccccc4)CC(C)(C)c5ccccc5)c6ccccc6 InChI=1/6C10H13.O.2Sn/c6*1-10(2,3)9-7-5-4-6-8-9;;;/h6*4-8H,1H2,2-3H3;;;/rC60H78OSn2/c1-55(2,49-31-19-13-20-32-49)43-62(44-56(3,4)50-33-21-14-22-34-50,45-57(5,6)51-35-23-15-24-36-51)61-63(46-58(7,8)52-37-25-16-26-38-52,47-59(9,10)53-39-27-17-28-40-53)48-60 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Belgium Fenbutatin oxide 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbutatin oxide. 01Sep2010 2010 doi:10.2903/j.efsa.2010.1711
+Fenbutatin oxide 236-407-7 13356-08-6 single chemical entity Component is identical to the substance Fenbutatin oxide 236-407-7 13356-08-6 hexakis(2-methyl-2-phenylpropyl)distannoxane Fenbutatin oxide C60H78OSn2 CC(C)(C[Sn](CC(C)(C)c1ccccc1)(CC(C)(C)c2ccccc2)O[Sn](CC(C)(C)c3ccccc3)(CC(C)(C)c4ccccc4)CC(C)(C)c5ccccc5)c6ccccc6 InChI=1/6C10H13.O.2Sn/c6*1-10(2,3)9-7-5-4-6-8-9;;;/h6*4-8H,1H2,2-3H3;;;/rC60H78OSn2/c1-55(2,49-31-19-13-20-32-49)43-62(44-56(3,4)50-33-21-14-22-34-50,45-57(5,6)51-35-23-15-24-36-51)61-63(46-58(7,8)52-37-25-16-26-38-52,47-59(9,10)53-39-27-17-28-40-53)48-60 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Belgium Fenbutatin oxide 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbutatin oxide. 01Sep2010 2010 doi:10.2903/j.efsa.2010.1711
+Fenbutatin oxide 236-407-7 13356-08-6 single chemical entity Component is identical to the substance Fenbutatin oxide 236-407-7 13356-08-6 hexakis(2-methyl-2-phenylpropyl)distannoxane Fenbutatin oxide C60H78OSn2 CC(C)(C[Sn](CC(C)(C)c1ccccc1)(CC(C)(C)c2ccccc2)O[Sn](CC(C)(C)c3ccccc3)(CC(C)(C)c4ccccc4)CC(C)(C)c5ccccc5)c6ccccc6 InChI=1/6C10H13.O.2Sn/c6*1-10(2,3)9-7-5-4-6-8-9;;;/h6*4-8H,1H2,2-3H3;;;/rC60H78OSn2/c1-55(2,49-31-19-13-20-32-49)43-62(44-56(3,4)50-33-21-14-22-34-50,45-57(5,6)51-35-23-15-24-36-51)61-63(46-58(7,8)52-37-25-16-26-38-52,47-59(9,10)53-39-27-17-28-40-53)48-60 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Belgium Fenbutatin oxide 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbutatin oxide. 01Sep2010 2010 doi:10.2903/j.efsa.2010.1711
+Fenbutatin oxide 236-407-7 13356-08-6 single chemical entity Component is identical to the substance Fenbutatin oxide 236-407-7 13356-08-6 hexakis(2-methyl-2-phenylpropyl)distannoxane Fenbutatin oxide C60H78OSn2 CC(C)(C[Sn](CC(C)(C)c1ccccc1)(CC(C)(C)c2ccccc2)O[Sn](CC(C)(C)c3ccccc3)(CC(C)(C)c4ccccc4)CC(C)(C)c5ccccc5)c6ccccc6 InChI=1/6C10H13.O.2Sn/c6*1-10(2,3)9-7-5-4-6-8-9;;;/h6*4-8H,1H2,2-3H3;;;/rC60H78OSn2/c1-55(2,49-31-19-13-20-32-49)43-62(44-56(3,4)50-33-21-14-22-34-50,45-57(5,6)51-35-23-15-24-36-51)61-63(46-58(7,8)52-37-25-16-26-38-52,47-59(9,10)53-39-27-17-28-40-53)48-60 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Belgium Fenbutatin oxide 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbutatin oxide. 01Sep2010 2010 doi:10.2903/j.efsa.2010.1711
+Fenbutatin oxide 236-407-7 13356-08-6 single chemical entity Component is identical to the substance Fenbutatin oxide 236-407-7 13356-08-6 hexakis(2-methyl-2-phenylpropyl)distannoxane Fenbutatin oxide C60H78OSn2 CC(C)(C[Sn](CC(C)(C)c1ccccc1)(CC(C)(C)c2ccccc2)O[Sn](CC(C)(C)c3ccccc3)(CC(C)(C)c4ccccc4)CC(C)(C)c5ccccc5)c6ccccc6 InChI=1/6C10H13.O.2Sn/c6*1-10(2,3)9-7-5-4-6-8-9;;;/h6*4-8H,1H2,2-3H3;;;/rC60H78OSn2/c1-55(2,49-31-19-13-20-32-49)43-62(44-56(3,4)50-33-21-14-22-34-50,45-57(5,6)51-35-23-15-24-36-51)61-63(46-58(7,8)52-37-25-16-26-38-52,47-59(9,10)53-39-27-17-28-40-53)48-60 organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Rat (as animal) hepatocytes Not reported yes without Negative RMS: Belgium Fenbutatin oxide 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbutatin oxide. 01Sep2010 2010 doi:10.2903/j.efsa.2010.1711
+Fenbutatin oxide 236-407-7 13356-08-6 single chemical entity Component is identical to the substance Fenbutatin oxide 236-407-7 13356-08-6 hexakis(2-methyl-2-phenylpropyl)distannoxane Fenbutatin oxide C60H78OSn2 CC(C)(C[Sn](CC(C)(C)c1ccccc1)(CC(C)(C)c2ccccc2)O[Sn](CC(C)(C)c3ccccc3)(CC(C)(C)c4ccccc4)CC(C)(C)c5ccccc5)c6ccccc6 InChI=1/6C10H13.O.2Sn/c6*1-10(2,3)9-7-5-4-6-8-9;;;/h6*4-8H,1H2,2-3H3;;;/rC60H78OSn2/c1-55(2,49-31-19-13-20-32-49)43-62(44-56(3,4)50-33-21-14-22-34-50,45-57(5,6)51-35-23-15-24-36-51)61-63(46-58(7,8)52-37-25-16-26-38-52,47-59(9,10)53-39-27-17-28-40-53)48-60 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 6 Male/Female oral: gavage 24.0000000000 h yes not applicable Negative direct evidence-cytotoxicity RMS: Belgium Fenbutatin oxide 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbutatin oxide. 01Sep2010 2010 doi:10.2903/j.efsa.2010.1711
+Fenbutatin oxide 236-407-7 13356-08-6 single chemical entity Component is identical to the substance Fenbutatin oxide 236-407-7 13356-08-6 hexakis(2-methyl-2-phenylpropyl)distannoxane Fenbutatin oxide C60H78OSn2 CC(C)(C[Sn](CC(C)(C)c1ccccc1)(CC(C)(C)c2ccccc2)O[Sn](CC(C)(C)c3ccccc3)(CC(C)(C)c4ccccc4)CC(C)(C)c5ccccc5)c6ccccc6 InChI=1/6C10H13.O.2Sn/c6*1-10(2,3)9-7-5-4-6-8-9;;;/h6*4-8H,1H2,2-3H3;;;/rC60H78OSn2/c1-55(2,49-31-19-13-20-32-49)43-62(44-56(3,4)50-33-21-14-22-34-50,45-57(5,6)51-35-23-15-24-36-51)61-63(46-58(7,8)52-37-25-16-26-38-52,47-59(9,10)53-39-27-17-28-40-53)48-60 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 6 Male/Female oral: gavage 72.0000000000 h yes not applicable Negative direct evidence-cytotoxicity RMS: Belgium Fenbutatin oxide 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbutatin oxide. 01Sep2010 2010 doi:10.2903/j.efsa.2010.1711
+Fenbutatin oxide 236-407-7 13356-08-6 single chemical entity Component is identical to the substance Fenbutatin oxide 236-407-7 13356-08-6 hexakis(2-methyl-2-phenylpropyl)distannoxane Fenbutatin oxide C60H78OSn2 CC(C)(C[Sn](CC(C)(C)c1ccccc1)(CC(C)(C)c2ccccc2)O[Sn](CC(C)(C)c3ccccc3)(CC(C)(C)c4ccccc4)CC(C)(C)c5ccccc5)c6ccccc6 InChI=1/6C10H13.O.2Sn/c6*1-10(2,3)9-7-5-4-6-8-9;;;/h6*4-8H,1H2,2-3H3;;;/rC60H78OSn2/c1-55(2,49-31-19-13-20-32-49)43-62(44-56(3,4)50-33-21-14-22-34-50,45-57(5,6)51-35-23-15-24-36-51)61-63(46-58(7,8)52-37-25-16-26-38-52,47-59(9,10)53-39-27-17-28-40-53)48-60 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 6 Male/Female oral: gavage 48.0000000000 h yes not applicable Negative direct evidence-cytotoxicity RMS: Belgium Fenbutatin oxide 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbutatin oxide. 01Sep2010 2010 doi:10.2903/j.efsa.2010.1711
+Fenbutatin oxide 236-407-7 13356-08-6 single chemical entity Component is identical to the substance Fenbutatin oxide 236-407-7 13356-08-6 hexakis(2-methyl-2-phenylpropyl)distannoxane Fenbutatin oxide C60H78OSn2 CC(C)(C[Sn](CC(C)(C)c1ccccc1)(CC(C)(C)c2ccccc2)O[Sn](CC(C)(C)c3ccccc3)(CC(C)(C)c4ccccc4)CC(C)(C)c5ccccc5)c6ccccc6 InChI=1/6C10H13.O.2Sn/c6*1-10(2,3)9-7-5-4-6-8-9;;;/h6*4-8H,1H2,2-3H3;;;/rC60H78OSn2/c1-55(2,49-31-19-13-20-32-49)43-62(44-56(3,4)50-33-21-14-22-34-50,45-57(5,6)51-35-23-15-24-36-51)61-63(46-58(7,8)52-37-25-16-26-38-52,47-59(9,10)53-39-27-17-28-40-53)48-60 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) CF-1 4 Male/Female intraperitoneal 8.0000000000 h yes not applicable Negative RMS: Belgium Fenbutatin oxide 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbutatin oxide. 01Sep2010 2010 doi:10.2903/j.efsa.2010.1711
+Fenbutatin oxide 236-407-7 13356-08-6 single chemical entity Component is identical to the substance Fenbutatin oxide 236-407-7 13356-08-6 hexakis(2-methyl-2-phenylpropyl)distannoxane Fenbutatin oxide C60H78OSn2 CC(C)(C[Sn](CC(C)(C)c1ccccc1)(CC(C)(C)c2ccccc2)O[Sn](CC(C)(C)c3ccccc3)(CC(C)(C)c4ccccc4)CC(C)(C)c5ccccc5)c6ccccc6 InChI=1/6C10H13.O.2Sn/c6*1-10(2,3)9-7-5-4-6-8-9;;;/h6*4-8H,1H2,2-3H3;;;/rC60H78OSn2/c1-55(2,49-31-19-13-20-32-49)43-62(44-56(3,4)50-33-21-14-22-34-50,45-57(5,6)51-35-23-15-24-36-51)61-63(46-58(7,8)52-37-25-16-26-38-52,47-59(9,10)53-39-27-17-28-40-53)48-60 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) CF-1 4 Male/Female intraperitoneal 24.0000000000 h yes not applicable Negative RMS: Belgium Fenbutatin oxide 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbutatin oxide. 01Sep2010 2010 doi:10.2903/j.efsa.2010.1711
+Fenbutatin oxide 236-407-7 13356-08-6 single chemical entity Component is identical to the substance Fenbutatin oxide 236-407-7 13356-08-6 hexakis(2-methyl-2-phenylpropyl)distannoxane Fenbutatin oxide C60H78OSn2 CC(C)(C[Sn](CC(C)(C)c1ccccc1)(CC(C)(C)c2ccccc2)O[Sn](CC(C)(C)c3ccccc3)(CC(C)(C)c4ccccc4)CC(C)(C)c5ccccc5)c6ccccc6 InChI=1/6C10H13.O.2Sn/c6*1-10(2,3)9-7-5-4-6-8-9;;;/h6*4-8H,1H2,2-3H3;;;/rC60H78OSn2/c1-55(2,49-31-19-13-20-32-49)43-62(44-56(3,4)50-33-21-14-22-34-50,45-57(5,6)51-35-23-15-24-36-51)61-63(46-58(7,8)52-37-25-16-26-38-52,47-59(9,10)53-39-27-17-28-40-53)48-60 organic compound Other Other chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) Yes Acceptable House mouse (as animal) CF-1 8 Male oral: gavage 7.0000000000 D yes not applicable Negative RMS: Belgium Fenbutatin oxide 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbutatin oxide. 01Sep2010 2010 doi:10.2903/j.efsa.2010.1711
+Fenitrothion 204-524-2 122-14-5 single chemical entity Component is identical to the substance Fenitrothion 204-524-2 122-14-5 O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate Fenitrothion C9H12NO5PS COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-] InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) W3102 E.coli Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fenitrothion 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion 22Feb2006 2006 doi:10.2903/j.efsa.2006.59r
+Fenitrothion 204-524-2 122-14-5 single chemical entity Component is identical to the substance Fenitrothion 204-524-2 122-14-5 O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate Fenitrothion C9H12NO5PS COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-] InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fenitrothion 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion 22Feb2006 2006 doi:10.2903/j.efsa.2006.59r
+Fenitrothion 204-524-2 122-14-5 single chemical entity Component is identical to the substance Fenitrothion 204-524-2 122-14-5 O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate Fenitrothion C9H12NO5PS COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-] InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fenitrothion 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion 22Feb2006 2006 doi:10.2903/j.efsa.2006.59r
+Fenitrothion 204-524-2 122-14-5 single chemical entity Component is identical to the substance Fenitrothion 204-524-2 122-14-5 O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate Fenitrothion C9H12NO5PS COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-] InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fenitrothion 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion 22Feb2006 2006 doi:10.2903/j.efsa.2006.59r
+Fenitrothion 204-524-2 122-14-5 single chemical entity Component is identical to the substance Fenitrothion 204-524-2 122-14-5 O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate Fenitrothion C9H12NO5PS COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-] InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fenitrothion 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion 22Feb2006 2006 doi:10.2903/j.efsa.2006.59r
+Fenitrothion 204-524-2 122-14-5 single chemical entity Component is identical to the substance Fenitrothion 204-524-2 122-14-5 O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate Fenitrothion C9H12NO5PS COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-] InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3 organic compound Other Other gene mutation Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes, concurrent vehicle no data Negative RMS: The United Kingdom Fenitrothion 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion 22Feb2006 2006 doi:10.2903/j.efsa.2006.59r
+Fenitrothion 204-524-2 122-14-5 single chemical entity Component is identical to the substance Fenitrothion 204-524-2 122-14-5 O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate Fenitrothion C9H12NO5PS COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-] InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fenitrothion 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion 22Feb2006 2006 doi:10.2903/j.efsa.2006.59r
+Fenitrothion 204-524-2 122-14-5 single chemical entity Component is identical to the substance Fenitrothion 204-524-2 122-14-5 O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate Fenitrothion C9H12NO5PS COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-] InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fenitrothion 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion 22Feb2006 2006 doi:10.2903/j.efsa.2006.59r
+Fenitrothion 204-524-2 122-14-5 single chemical entity Component is identical to the substance Fenitrothion 204-524-2 122-14-5 O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate Fenitrothion C9H12NO5PS COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-] InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) G46 Not reported yes, concurrent vehicle no data Negative RMS: The United Kingdom Fenitrothion 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion 22Feb2006 2006 doi:10.2903/j.efsa.2006.59r
+Fenitrothion 204-524-2 122-14-5 single chemical entity Component is identical to the substance Fenitrothion 204-524-2 122-14-5 O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate Fenitrothion C9H12NO5PS COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-] InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) W3102 E.coli Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fenitrothion 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion 22Feb2006 2006 doi:10.2903/j.efsa.2006.59r
+Fenitrothion 204-524-2 122-14-5 single chemical entity Component is identical to the substance Fenitrothion 204-524-2 122-14-5 O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate Fenitrothion C9H12NO5PS COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-] InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3 organic compound Other Other gene mutation Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes, concurrent vehicle no data Negative RMS: The United Kingdom Fenitrothion 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion 22Feb2006 2006 doi:10.2903/j.efsa.2006.59r
+Fenitrothion 204-524-2 122-14-5 single chemical entity Component is identical to the substance Fenitrothion 204-524-2 122-14-5 O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate Fenitrothion C9H12NO5PS COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-] InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fenitrothion 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion 22Feb2006 2006 doi:10.2903/j.efsa.2006.59r
+Fenitrothion 204-524-2 122-14-5 single chemical entity Component is identical to the substance Fenitrothion 204-524-2 122-14-5 O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate Fenitrothion C9H12NO5PS COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-] InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fenitrothion 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion 22Feb2006 2006 doi:10.2903/j.efsa.2006.59r
+Fenitrothion 204-524-2 122-14-5 single chemical entity Component is identical to the substance Fenitrothion 204-524-2 122-14-5 O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate Fenitrothion C9H12NO5PS COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-] InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fenitrothion 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion 22Feb2006 2006 doi:10.2903/j.efsa.2006.59r
+Fenitrothion 204-524-2 122-14-5 single chemical entity Component is identical to the substance Fenitrothion 204-524-2 122-14-5 O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate Fenitrothion C9H12NO5PS COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-] InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Positive RMS: The United Kingdom Fenitrothion 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion 22Feb2006 2006 doi:10.2903/j.efsa.2006.59r
+Fenitrothion 204-524-2 122-14-5 single chemical entity Component is identical to the substance Fenitrothion 204-524-2 122-14-5 O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate Fenitrothion C9H12NO5PS COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-] InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fenitrothion 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion 22Feb2006 2006 doi:10.2903/j.efsa.2006.59r
+Fenitrothion 204-524-2 122-14-5 single chemical entity Component is identical to the substance Fenitrothion 204-524-2 122-14-5 O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate Fenitrothion C9H12NO5PS COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-] InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fenitrothion 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion 22Feb2006 2006 doi:10.2903/j.efsa.2006.59r
+Fenitrothion 204-524-2 122-14-5 single chemical entity Component is identical to the substance Fenitrothion 204-524-2 122-14-5 O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate Fenitrothion C9H12NO5PS COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-] InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fenitrothion 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion 22Feb2006 2006 doi:10.2903/j.efsa.2006.59r
+Fenitrothion 204-524-2 122-14-5 single chemical entity Component is identical to the substance Fenitrothion 204-524-2 122-14-5 O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate Fenitrothion C9H12NO5PS COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-] InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fenitrothion 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion 22Feb2006 2006 doi:10.2903/j.efsa.2006.59r
+Fenitrothion 204-524-2 122-14-5 single chemical entity Component is identical to the substance Fenitrothion 204-524-2 122-14-5 O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate Fenitrothion C9H12NO5PS COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-] InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fenitrothion 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion 22Feb2006 2006 doi:10.2903/j.efsa.2006.59r
+Fenitrothion 204-524-2 122-14-5 single chemical entity Component is identical to the substance Fenitrothion 204-524-2 122-14-5 O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate Fenitrothion C9H12NO5PS COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-] InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fenitrothion 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion 22Feb2006 2006 doi:10.2903/j.efsa.2006.59r
+Fenitrothion 204-524-2 122-14-5 single chemical entity Component is identical to the substance Fenitrothion 204-524-2 122-14-5 O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate Fenitrothion C9H12NO5PS COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-] InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fenitrothion 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion 22Feb2006 2006 doi:10.2903/j.efsa.2006.59r
+Fenitrothion 204-524-2 122-14-5 single chemical entity Component is identical to the substance Fenitrothion 204-524-2 122-14-5 O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate Fenitrothion C9H12NO5PS COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-] InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fenitrothion 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion 22Feb2006 2006 doi:10.2903/j.efsa.2006.59r
+Fenitrothion 204-524-2 122-14-5 single chemical entity Component is identical to the substance Fenitrothion 204-524-2 122-14-5 O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate Fenitrothion C9H12NO5PS COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-] InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fenitrothion 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion 22Feb2006 2006 doi:10.2903/j.efsa.2006.59r
+Fenitrothion 204-524-2 122-14-5 single chemical entity Component is identical to the substance Fenitrothion 204-524-2 122-14-5 O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate Fenitrothion C9H12NO5PS COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-] InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fenitrothion 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion 22Feb2006 2006 doi:10.2903/j.efsa.2006.59r
+Fenitrothion 204-524-2 122-14-5 single chemical entity Component is identical to the substance Fenitrothion 204-524-2 122-14-5 O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate Fenitrothion C9H12NO5PS COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-] InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fenitrothion 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion 22Feb2006 2006 doi:10.2903/j.efsa.2006.59r
+Fenitrothion 204-524-2 122-14-5 single chemical entity Component is identical to the substance Fenitrothion 204-524-2 122-14-5 O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate Fenitrothion C9H12NO5PS COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-] InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fenitrothion 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion 22Feb2006 2006 doi:10.2903/j.efsa.2006.59r
+Fenitrothion 204-524-2 122-14-5 single chemical entity Component is identical to the substance Fenitrothion 204-524-2 122-14-5 O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate Fenitrothion C9H12NO5PS COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-] InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fenitrothion 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion 22Feb2006 2006 doi:10.2903/j.efsa.2006.59r
+Fenitrothion 204-524-2 122-14-5 single chemical entity Component is identical to the substance Fenitrothion 204-524-2 122-14-5 O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate Fenitrothion C9H12NO5PS COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-] InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fenitrothion 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion 22Feb2006 2006 doi:10.2903/j.efsa.2006.59r
+Fenitrothion 204-524-2 122-14-5 single chemical entity Component is identical to the substance Fenitrothion 204-524-2 122-14-5 O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate Fenitrothion C9H12NO5PS COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-] InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: The United Kingdom Fenitrothion 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion 22Feb2006 2006 doi:10.2903/j.efsa.2006.59r
+Fenitrothion 204-524-2 122-14-5 single chemical entity Component is identical to the substance Fenitrothion 204-524-2 122-14-5 O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate Fenitrothion C9H12NO5PS COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-] InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: The United Kingdom Fenitrothion 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion 22Feb2006 2006 doi:10.2903/j.efsa.2006.59r
+Fenitrothion 204-524-2 122-14-5 single chemical entity Component is identical to the substance Fenitrothion 204-524-2 122-14-5 O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate Fenitrothion C9H12NO5PS COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-] InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3 organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) Yes Acceptable House mouse (as animal) Not reported Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fenitrothion 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion 22Feb2006 2006 doi:10.2903/j.efsa.2006.59r
+Fenitrothion 204-524-2 122-14-5 single chemical entity Component is identical to the substance Fenitrothion 204-524-2 122-14-5 O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate Fenitrothion C9H12NO5PS COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-] InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3 organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) Yes Acceptable House mouse (as animal) Not reported Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fenitrothion 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion 22Feb2006 2006 doi:10.2903/j.efsa.2006.59r
+Fenitrothion 204-524-2 122-14-5 single chemical entity Component is identical to the substance Fenitrothion 204-524-2 122-14-5 O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate Fenitrothion C9H12NO5PS COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-] InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable House mouse (as animal) ICR 6 Male intraperitoneal 48.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Fenitrothion 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion 22Feb2006 2006 doi:10.2903/j.efsa.2006.59r
+Fenitrothion 204-524-2 122-14-5 single chemical entity Component is identical to the substance Fenitrothion 204-524-2 122-14-5 O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate Fenitrothion C9H12NO5PS COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-] InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable House mouse (as animal) ICR 6 Male intraperitoneal 6.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Fenitrothion 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion 22Feb2006 2006 doi:10.2903/j.efsa.2006.59r
+Fenitrothion 204-524-2 122-14-5 single chemical entity Component is identical to the substance Fenitrothion 204-524-2 122-14-5 O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate Fenitrothion C9H12NO5PS COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-] InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable House mouse (as animal) ICR 6 Male intraperitoneal 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Fenitrothion 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion 22Feb2006 2006 doi:10.2903/j.efsa.2006.59r
+Fenitrothion 204-524-2 122-14-5 single chemical entity Component is identical to the substance Fenitrothion 204-524-2 122-14-5 O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate Fenitrothion C9H12NO5PS COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-] InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Rat (as animal) Sprague-Dawley 6 Male oral: unspecified 6.0000000000 h yes not applicable Negative RMS: The United Kingdom Fenitrothion 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion 22Feb2006 2006 doi:10.2903/j.efsa.2006.59r
+Fenitrothion 204-524-2 122-14-5 single chemical entity Component is identical to the substance Fenitrothion 204-524-2 122-14-5 O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate Fenitrothion C9H12NO5PS COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-] InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Rat (as animal) Sprague-Dawley 6 Male oral: unspecified 48.0000000000 h yes not applicable Negative RMS: The United Kingdom Fenitrothion 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion 22Feb2006 2006 doi:10.2903/j.efsa.2006.59r
+Fenitrothion 204-524-2 122-14-5 single chemical entity Component is identical to the substance Fenitrothion 204-524-2 122-14-5 O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate Fenitrothion C9H12NO5PS COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-] InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3 organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Rat (as animal) Sprague-Dawley 6 Male oral: unspecified 24.0000000000 h yes not applicable Negative RMS: The United Kingdom Fenitrothion 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion 22Feb2006 2006 doi:10.2903/j.efsa.2006.59r
+Fenitrothion 204-524-2 122-14-5 single chemical entity Component is identical to the substance Fenitrothion 204-524-2 122-14-5 O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate Fenitrothion C9H12NO5PS COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-] InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) ICR 6 Male intraperitoneal 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The United Kingdom Fenitrothion 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion 22Feb2006 2006 doi:10.2903/j.efsa.2006.59r
+Fenitrothion 204-524-2 122-14-5 single chemical entity Component is identical to the substance Fenitrothion 204-524-2 122-14-5 O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate Fenitrothion C9H12NO5PS COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-] InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3 organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Sprague-Dawley 3 Male Not reported 24.0000000000 h yes not applicable Negative RMS: The United Kingdom Fenitrothion 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion 22Feb2006 2006 doi:10.2903/j.efsa.2006.59r
+Fenitrothion 204-524-2 122-14-5 single chemical entity Component is identical to the substance Fenitrothion 204-524-2 122-14-5 O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate Fenitrothion C9H12NO5PS COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-] InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3 organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Sprague-Dawley 3 Male Not reported 12.0000000000 h yes not applicable Negative RMS: The United Kingdom Fenitrothion 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion 22Feb2006 2006 doi:10.2903/j.efsa.2006.59r
+Fenitrothion 204-524-2 122-14-5 single chemical entity Component is identical to the substance Fenitrothion 204-524-2 122-14-5 O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate Fenitrothion C9H12NO5PS COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-] InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3 organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Sprague-Dawley 3 Male Not reported 3.0000000000 h yes not applicable Negative RMS: The United Kingdom Fenitrothion 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion 22Feb2006 2006 doi:10.2903/j.efsa.2006.59r
+Fenitrothion 204-524-2 122-14-5 single chemical entity Component is identical to the substance Fenitrothion 204-524-2 122-14-5 O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate Fenitrothion C9H12NO5PS COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-] InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3 organic compound Other Other chromosome aberration dominant lethal assay in vivo According to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) No Acceptable House mouse (as animal) ICR 12 Male oral: gavage 5.0000000000 D yes not applicable Negative RMS: The United Kingdom Fenitrothion 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion 22Feb2006 2006 doi:10.2903/j.efsa.2006.59r
+Fenitrothion 204-524-2 122-14-5 single chemical entity Component is identical to the substance Fenitrothion 204-524-2 122-14-5 O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate Fenitrothion C9H12NO5PS COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-] InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3 organic compound Other Other chromosome aberration dominant lethal assay in vivo According to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) No Acceptable Rat (as animal) Sprague-Dawley 11 Male oral: gavage 5.0000000000 D yes not applicable Negative RMS: The United Kingdom Fenitrothion 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion 22Feb2006 2006 doi:10.2903/j.efsa.2006.59r
+Fenpropimorph 266-719-9 67564-91-4 single chemical entity Component is identical to the substance Fenpropimorph 266-719-9 67564-91-4 (2R,6S)-4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine Fenpropimorph C20H33NO CC(C)(C)C(C=C2)=CC=C2CC(C)CN1C[C@@H](C)O[C@@H](C)C1 InChI=1S/C20H33NO/c1-15(12-21-13-16(2)22-17(3)14-21)11-18-7-9-19(10-8-18)20(4,5)6/h7-10,15-17H,11-14H2,1-6H3/t15?,16-,17+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany Fenpropimorph 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropimorph 29Jul2008 2008 doi:10.2903/j.efsa.2008.144r
+Fenpropimorph 266-719-9 67564-91-4 single chemical entity Component is identical to the substance Fenpropimorph 266-719-9 67564-91-4 (2R,6S)-4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine Fenpropimorph C20H33NO CC(C)(C)C(C=C2)=CC=C2CC(C)CN1C[C@@H](C)O[C@@H](C)C1 InChI=1S/C20H33NO/c1-15(12-21-13-16(2)22-17(3)14-21)11-18-7-9-19(10-8-18)20(4,5)6/h7-10,15-17H,11-14H2,1-6H3/t15?,16-,17+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany Fenpropimorph 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropimorph 29Jul2008 2008 doi:10.2903/j.efsa.2008.144r
+Fenpropimorph 266-719-9 67564-91-4 single chemical entity Component is identical to the substance Fenpropimorph 266-719-9 67564-91-4 (2R,6S)-4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine Fenpropimorph C20H33NO CC(C)(C)C(C=C2)=CC=C2CC(C)CN1C[C@@H](C)O[C@@H](C)C1 InChI=1S/C20H33NO/c1-15(12-21-13-16(2)22-17(3)14-21)11-18-7-9-19(10-8-18)20(4,5)6/h7-10,15-17H,11-14H2,1-6H3/t15?,16-,17+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany Fenpropimorph 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropimorph 29Jul2008 2008 doi:10.2903/j.efsa.2008.144r
+Fenpropimorph 266-719-9 67564-91-4 single chemical entity Component is identical to the substance Fenpropimorph 266-719-9 67564-91-4 (2R,6S)-4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine Fenpropimorph C20H33NO CC(C)(C)C(C=C2)=CC=C2CC(C)CN1C[C@@H](C)O[C@@H](C)C1 InChI=1S/C20H33NO/c1-15(12-21-13-16(2)22-17(3)14-21)11-18-7-9-19(10-8-18)20(4,5)6/h7-10,15-17H,11-14H2,1-6H3/t15?,16-,17+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany Fenpropimorph 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropimorph 29Jul2008 2008 doi:10.2903/j.efsa.2008.144r
+Fenpropimorph 266-719-9 67564-91-4 single chemical entity Component is identical to the substance Fenpropimorph 266-719-9 67564-91-4 (2R,6S)-4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine Fenpropimorph C20H33NO CC(C)(C)C(C=C2)=CC=C2CC(C)CN1C[C@@H](C)O[C@@H](C)C1 InChI=1S/C20H33NO/c1-15(12-21-13-16(2)22-17(3)14-21)11-18-7-9-19(10-8-18)20(4,5)6/h7-10,15-17H,11-14H2,1-6H3/t15?,16-,17+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany Fenpropimorph 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropimorph 29Jul2008 2008 doi:10.2903/j.efsa.2008.144r
+Fenpropimorph 266-719-9 67564-91-4 single chemical entity Component is identical to the substance Fenpropimorph 266-719-9 67564-91-4 (2R,6S)-4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine Fenpropimorph C20H33NO CC(C)(C)C(C=C2)=CC=C2CC(C)CN1C[C@@H](C)O[C@@H](C)C1 InChI=1S/C20H33NO/c1-15(12-21-13-16(2)22-17(3)14-21)11-18-7-9-19(10-8-18)20(4,5)6/h7-10,15-17H,11-14H2,1-6H3/t15?,16-,17+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany Fenpropimorph 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropimorph 29Jul2008 2008 doi:10.2903/j.efsa.2008.144r
+Fenpropimorph 266-719-9 67564-91-4 single chemical entity Component is identical to the substance Fenpropimorph 266-719-9 67564-91-4 (2R,6S)-4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine Fenpropimorph C20H33NO CC(C)(C)C(C=C2)=CC=C2CC(C)CN1C[C@@H](C)O[C@@H](C)C1 InChI=1S/C20H33NO/c1-15(12-21-13-16(2)22-17(3)14-21)11-18-7-9-19(10-8-18)20(4,5)6/h7-10,15-17H,11-14H2,1-6H3/t15?,16-,17+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany Fenpropimorph 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropimorph 29Jul2008 2008 doi:10.2903/j.efsa.2008.144r
+Fenpropimorph 266-719-9 67564-91-4 single chemical entity Component is identical to the substance Fenpropimorph 266-719-9 67564-91-4 (2R,6S)-4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine Fenpropimorph C20H33NO CC(C)(C)C(C=C2)=CC=C2CC(C)CN1C[C@@H](C)O[C@@H](C)C1 InChI=1S/C20H33NO/c1-15(12-21-13-16(2)22-17(3)14-21)11-18-7-9-19(10-8-18)20(4,5)6/h7-10,15-17H,11-14H2,1-6H3/t15?,16-,17+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany Fenpropimorph 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropimorph 29Jul2008 2008 doi:10.2903/j.efsa.2008.144r
+Fenpropimorph 266-719-9 67564-91-4 single chemical entity Component is identical to the substance Fenpropimorph 266-719-9 67564-91-4 (2R,6S)-4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine Fenpropimorph C20H33NO CC(C)(C)C(C=C2)=CC=C2CC(C)CN1C[C@@H](C)O[C@@H](C)C1 InChI=1S/C20H33NO/c1-15(12-21-13-16(2)22-17(3)14-21)11-18-7-9-19(10-8-18)20(4,5)6/h7-10,15-17H,11-14H2,1-6H3/t15?,16-,17+ organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Germany Fenpropimorph 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropimorph 29Jul2008 2008 doi:10.2903/j.efsa.2008.144r
+Fenpropimorph 266-719-9 67564-91-4 single chemical entity Component is identical to the substance Fenpropimorph 266-719-9 67564-91-4 (2R,6S)-4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine Fenpropimorph C20H33NO CC(C)(C)C(C=C2)=CC=C2CC(C)CN1C[C@@H](C)O[C@@H](C)C1 InChI=1S/C20H33NO/c1-15(12-21-13-16(2)22-17(3)14-21)11-18-7-9-19(10-8-18)20(4,5)6/h7-10,15-17H,11-14H2,1-6H3/t15?,16-,17+ organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Germany Fenpropimorph 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropimorph 29Jul2008 2008 doi:10.2903/j.efsa.2008.144r
+Fenpropimorph 266-719-9 67564-91-4 single chemical entity Component is identical to the substance Fenpropimorph 266-719-9 67564-91-4 (2R,6S)-4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine Fenpropimorph C20H33NO CC(C)(C)C(C=C2)=CC=C2CC(C)CN1C[C@@H](C)O[C@@H](C)C1 InChI=1S/C20H33NO/c1-15(12-21-13-16(2)22-17(3)14-21)11-18-7-9-19(10-8-18)20(4,5)6/h7-10,15-17H,11-14H2,1-6H3/t15?,16-,17+ organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: Germany Fenpropimorph 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropimorph 29Jul2008 2008 doi:10.2903/j.efsa.2008.144r
+Fenpropimorph 266-719-9 67564-91-4 single chemical entity Component is identical to the substance Fenpropimorph 266-719-9 67564-91-4 (2R,6S)-4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine Fenpropimorph C20H33NO CC(C)(C)C(C=C2)=CC=C2CC(C)CN1C[C@@H](C)O[C@@H](C)C1 InChI=1S/C20H33NO/c1-15(12-21-13-16(2)22-17(3)14-21)11-18-7-9-19(10-8-18)20(4,5)6/h7-10,15-17H,11-14H2,1-6H3/t15?,16-,17+ organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Ambiguous RMS: Germany Fenpropimorph 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropimorph 29Jul2008 2008 doi:10.2903/j.efsa.2008.144r
+Fenpropimorph 266-719-9 67564-91-4 single chemical entity Component is identical to the substance Fenpropimorph 266-719-9 67564-91-4 (2R,6S)-4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine Fenpropimorph C20H33NO CC(C)(C)C(C=C2)=CC=C2CC(C)CN1C[C@@H](C)O[C@@H](C)C1 InChI=1S/C20H33NO/c1-15(12-21-13-16(2)22-17(3)14-21)11-18-7-9-19(10-8-18)20(4,5)6/h7-10,15-17H,11-14H2,1-6H3/t15?,16-,17+ organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Germany Fenpropimorph 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropimorph 29Jul2008 2008 doi:10.2903/j.efsa.2008.144r
+Fenpropimorph 266-719-9 67564-91-4 single chemical entity Component is identical to the substance Fenpropimorph 266-719-9 67564-91-4 (2R,6S)-4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine Fenpropimorph C20H33NO CC(C)(C)C(C=C2)=CC=C2CC(C)CN1C[C@@H](C)O[C@@H](C)C1 InChI=1S/C20H33NO/c1-15(12-21-13-16(2)22-17(3)14-21)11-18-7-9-19(10-8-18)20(4,5)6/h7-10,15-17H,11-14H2,1-6H3/t15?,16-,17+ organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Germany Fenpropimorph 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropimorph 29Jul2008 2008 doi:10.2903/j.efsa.2008.144r
+Fenpropimorph 266-719-9 67564-91-4 single chemical entity Component is identical to the substance Fenpropimorph 266-719-9 67564-91-4 (2R,6S)-4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine Fenpropimorph C20H33NO CC(C)(C)C(C=C2)=CC=C2CC(C)CN1C[C@@H](C)O[C@@H](C)C1 InChI=1S/C20H33NO/c1-15(12-21-13-16(2)22-17(3)14-21)11-18-7-9-19(10-8-18)20(4,5)6/h7-10,15-17H,11-14H2,1-6H3/t15?,16-,17+ organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Germany Fenpropimorph 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropimorph 29Jul2008 2008 doi:10.2903/j.efsa.2008.144r
+Fenpropimorph 266-719-9 67564-91-4 single chemical entity Component is identical to the substance Fenpropimorph 266-719-9 67564-91-4 (2R,6S)-4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine Fenpropimorph C20H33NO CC(C)(C)C(C=C2)=CC=C2CC(C)CN1C[C@@H](C)O[C@@H](C)C1 InChI=1S/C20H33NO/c1-15(12-21-13-16(2)22-17(3)14-21)11-18-7-9-19(10-8-18)20(4,5)6/h7-10,15-17H,11-14H2,1-6H3/t15?,16-,17+ organic compound Other Other gene mutation yeast cytogenetic assay in vitro According to OECD Guideline 480 (Genetic Toxicology: Saccharomyces cerevisiae, Gene Mutation Assay) No Acceptable Saccharomyces cerevisiae (as organism) D7 Not reported yes, concurrent vehicle with Negative RMS: Germany Fenpropimorph 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropimorph 29Jul2008 2008 doi:10.2903/j.efsa.2008.144r
+Fenpropimorph 266-719-9 67564-91-4 single chemical entity Component is identical to the substance Fenpropimorph 266-719-9 67564-91-4 (2R,6S)-4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine Fenpropimorph C20H33NO CC(C)(C)C(C=C2)=CC=C2CC(C)CN1C[C@@H](C)O[C@@H](C)C1 InChI=1S/C20H33NO/c1-15(12-21-13-16(2)22-17(3)14-21)11-18-7-9-19(10-8-18)20(4,5)6/h7-10,15-17H,11-14H2,1-6H3/t15?,16-,17+ organic compound Other Other gene mutation yeast cytogenetic assay in vitro According to OECD Guideline 480 (Genetic Toxicology: Saccharomyces cerevisiae, Gene Mutation Assay) No Acceptable Saccharomyces cerevisiae (as organism) D7 Not reported yes, concurrent vehicle without Negative RMS: Germany Fenpropimorph 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropimorph 29Jul2008 2008 doi:10.2903/j.efsa.2008.144r
+Fenpropimorph 266-719-9 67564-91-4 single chemical entity Component is identical to the substance Fenpropimorph 266-719-9 67564-91-4 (2R,6S)-4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine Fenpropimorph C20H33NO CC(C)(C)C(C=C2)=CC=C2CC(C)CN1C[C@@H](C)O[C@@H](C)C1 InChI=1S/C20H33NO/c1-15(12-21-13-16(2)22-17(3)14-21)11-18-7-9-19(10-8-18)20(4,5)6/h7-10,15-17H,11-14H2,1-6H3/t15?,16-,17+ organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 5 Male/Female intraperitoneal 48.0000000000 h yes not applicable Negative indirect evidence-systemic toxicity RMS: Germany Fenpropimorph 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropimorph 29Jul2008 2008 doi:10.2903/j.efsa.2008.144r
+Fenpropimorph 266-719-9 67564-91-4 single chemical entity Component is identical to the substance Fenpropimorph 266-719-9 67564-91-4 (2R,6S)-4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine Fenpropimorph C20H33NO CC(C)(C)C(C=C2)=CC=C2CC(C)CN1C[C@@H](C)O[C@@H](C)C1 InChI=1S/C20H33NO/c1-15(12-21-13-16(2)22-17(3)14-21)11-18-7-9-19(10-8-18)20(4,5)6/h7-10,15-17H,11-14H2,1-6H3/t15?,16-,17+ organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 5 Male/Female intraperitoneal 24.0000000000 h yes not applicable Negative indirect evidence-systemic toxicity RMS: Germany Fenpropimorph 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropimorph 29Jul2008 2008 doi:10.2903/j.efsa.2008.144r
+Fenpropimorph 266-719-9 67564-91-4 single chemical entity Component is identical to the substance Fenpropimorph 266-719-9 67564-91-4 (2R,6S)-4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine Fenpropimorph C20H33NO CC(C)(C)C(C=C2)=CC=C2CC(C)CN1C[C@@H](C)O[C@@H](C)C1 InChI=1S/C20H33NO/c1-15(12-21-13-16(2)22-17(3)14-21)11-18-7-9-19(10-8-18)20(4,5)6/h7-10,15-17H,11-14H2,1-6H3/t15?,16-,17+ organic compound Other Other chromosome aberration dominant lethal assay in vivo According to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) No Acceptable House mouse (as animal) NMRI 40 Male intraperitoneal 18.0000000000 D yes, concurrent vehicle not applicable Negative RMS: Germany Fenpropimorph 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropimorph 29Jul2008 2008 doi:10.2903/j.efsa.2008.144r
+Flubendiamide 272451-65-7 single chemical entity Component is identical to the substance Flubendiamide 272451-65-7 3-iodo-N'-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide Flubendiamide C23H22F7IN2O4S CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Greece Flubendiamide 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide. 09Sep2013 2013 doi:10.2903/j.efsa.2013.3298
+Flubendiamide 272451-65-7 single chemical entity Component is identical to the substance Flubendiamide 272451-65-7 3-iodo-N'-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide Flubendiamide C23H22F7IN2O4S CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Greece Flubendiamide 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide. 09Sep2013 2013 doi:10.2903/j.efsa.2013.3298
+Flubendiamide 272451-65-7 single chemical entity Component is identical to the substance Flubendiamide 272451-65-7 3-iodo-N'-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide Flubendiamide C23H22F7IN2O4S CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Greece Flubendiamide 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide. 09Sep2013 2013 doi:10.2903/j.efsa.2013.3298
+Flubendiamide 272451-65-7 single chemical entity Component is identical to the substance Flubendiamide 272451-65-7 3-iodo-N'-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide Flubendiamide C23H22F7IN2O4S CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Greece Flubendiamide 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide. 09Sep2013 2013 doi:10.2903/j.efsa.2013.3298
+Flubendiamide 272451-65-7 single chemical entity Component is identical to the substance Flubendiamide 272451-65-7 3-iodo-N'-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide Flubendiamide C23H22F7IN2O4S CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Greece Flubendiamide 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide. 09Sep2013 2013 doi:10.2903/j.efsa.2013.3298
+Flubendiamide 272451-65-7 single chemical entity Component is identical to the substance Flubendiamide 272451-65-7 3-iodo-N'-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide Flubendiamide C23H22F7IN2O4S CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Greece Flubendiamide 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide. 09Sep2013 2013 doi:10.2903/j.efsa.2013.3298
+Flubendiamide 272451-65-7 single chemical entity Component is identical to the substance Flubendiamide 272451-65-7 3-iodo-N'-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide Flubendiamide C23H22F7IN2O4S CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Greece Flubendiamide 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide. 09Sep2013 2013 doi:10.2903/j.efsa.2013.3298
+Flubendiamide 272451-65-7 single chemical entity Component is identical to the substance Flubendiamide 272451-65-7 3-iodo-N'-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide Flubendiamide C23H22F7IN2O4S CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Greece Flubendiamide 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide. 09Sep2013 2013 doi:10.2903/j.efsa.2013.3298
+Flubendiamide 272451-65-7 single chemical entity Component is identical to the substance Flubendiamide 272451-65-7 3-iodo-N'-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide Flubendiamide C23H22F7IN2O4S CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Greece Flubendiamide 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide. 09Sep2013 2013 doi:10.2903/j.efsa.2013.3298
+Flubendiamide 272451-65-7 single chemical entity Component is identical to the substance Flubendiamide 272451-65-7 3-iodo-N'-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide Flubendiamide C23H22F7IN2O4S CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Greece Flubendiamide 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide. 09Sep2013 2013 doi:10.2903/j.efsa.2013.3298
+Flubendiamide 272451-65-7 single chemical entity Component is identical to the substance Flubendiamide 272451-65-7 3-iodo-N'-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide Flubendiamide C23H22F7IN2O4S CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: Greece Flubendiamide 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide. 09Sep2013 2013 doi:10.2903/j.efsa.2013.3298
+Flubendiamide 272451-65-7 single chemical entity Component is identical to the substance Flubendiamide 272451-65-7 3-iodo-N'-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide Flubendiamide C23H22F7IN2O4S CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: Greece Flubendiamide 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide. 09Sep2013 2013 doi:10.2903/j.efsa.2013.3298
+Flubendiamide 272451-65-7 single chemical entity Component is identical to the substance Flubendiamide 272451-65-7 3-iodo-N'-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide Flubendiamide C23H22F7IN2O4S CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Greece Flubendiamide 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide. 09Sep2013 2013 doi:10.2903/j.efsa.2013.3298
+Flubendiamide 272451-65-7 single chemical entity Component is identical to the substance Flubendiamide 272451-65-7 3-iodo-N'-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide Flubendiamide C23H22F7IN2O4S CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Greece Flubendiamide 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide. 09Sep2013 2013 doi:10.2903/j.efsa.2013.3298
+Flubendiamide 272451-65-7 single chemical entity Component is identical to the substance Flubendiamide 272451-65-7 3-iodo-N'-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide Flubendiamide C23H22F7IN2O4S CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 5 Male intraperitoneal 24.0000000000 h yes not applicable Negative direct evidence-cytotoxicity$indirect evidence-systemic toxicity RMS: Greece Flubendiamide 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide. 09Sep2013 2013 doi:10.2903/j.efsa.2013.3298
+Flubendiamide 272451-65-7 single chemical entity Component is a metabolite of the substance N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide Not in list C23H23F7N2O4S Cc2cc(ccc2NC(=O)c1ccccc1C(=O)NC(C)(C)CS(C)(=O)=O)C(F)(C(F)(F)F)C(F)(F)F InChI=1/C23H23F7N2O4S/c1-13-11-14(21(24,22(25,26)27)23(28,29)30)9-10-17(13)31-18(33)15-7-5-6-8-16(15)19(34)32-20(2,3)12-37(4,35)36/h5-11H,12H2,1-4H3,(H,31,33)(H,32,34) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Greece Flubendiamide 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide. 09Sep2013 2013 doi:10.2903/j.efsa.2013.3298
+Flubendiamide 272451-65-7 single chemical entity Component is a metabolite of the substance N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide Not in list C23H23F7N2O4S Cc2cc(ccc2NC(=O)c1ccccc1C(=O)NC(C)(C)CS(C)(=O)=O)C(F)(C(F)(F)F)C(F)(F)F InChI=1/C23H23F7N2O4S/c1-13-11-14(21(24,22(25,26)27)23(28,29)30)9-10-17(13)31-18(33)15-7-5-6-8-16(15)19(34)32-20(2,3)12-37(4,35)36/h5-11H,12H2,1-4H3,(H,31,33)(H,32,34) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Greece Flubendiamide 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide. 09Sep2013 2013 doi:10.2903/j.efsa.2013.3298
+Flubendiamide 272451-65-7 single chemical entity Component is a metabolite of the substance N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide Not in list C23H23F7N2O4S Cc2cc(ccc2NC(=O)c1ccccc1C(=O)NC(C)(C)CS(C)(=O)=O)C(F)(C(F)(F)F)C(F)(F)F InChI=1/C23H23F7N2O4S/c1-13-11-14(21(24,22(25,26)27)23(28,29)30)9-10-17(13)31-18(33)15-7-5-6-8-16(15)19(34)32-20(2,3)12-37(4,35)36/h5-11H,12H2,1-4H3,(H,31,33)(H,32,34) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Greece Flubendiamide 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide. 09Sep2013 2013 doi:10.2903/j.efsa.2013.3298
+Flubendiamide 272451-65-7 single chemical entity Component is a metabolite of the substance N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide Not in list C23H23F7N2O4S Cc2cc(ccc2NC(=O)c1ccccc1C(=O)NC(C)(C)CS(C)(=O)=O)C(F)(C(F)(F)F)C(F)(F)F InChI=1/C23H23F7N2O4S/c1-13-11-14(21(24,22(25,26)27)23(28,29)30)9-10-17(13)31-18(33)15-7-5-6-8-16(15)19(34)32-20(2,3)12-37(4,35)36/h5-11H,12H2,1-4H3,(H,31,33)(H,32,34) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Greece Flubendiamide 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide. 09Sep2013 2013 doi:10.2903/j.efsa.2013.3298
+Flubendiamide 272451-65-7 single chemical entity Component is a metabolite of the substance N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide Not in list C23H23F7N2O4S Cc2cc(ccc2NC(=O)c1ccccc1C(=O)NC(C)(C)CS(C)(=O)=O)C(F)(C(F)(F)F)C(F)(F)F InChI=1/C23H23F7N2O4S/c1-13-11-14(21(24,22(25,26)27)23(28,29)30)9-10-17(13)31-18(33)15-7-5-6-8-16(15)19(34)32-20(2,3)12-37(4,35)36/h5-11H,12H2,1-4H3,(H,31,33)(H,32,34) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Greece Flubendiamide 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide. 09Sep2013 2013 doi:10.2903/j.efsa.2013.3298
+Flubendiamide 272451-65-7 single chemical entity Component is a metabolite of the substance N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide Not in list C23H23F7N2O4S Cc2cc(ccc2NC(=O)c1ccccc1C(=O)NC(C)(C)CS(C)(=O)=O)C(F)(C(F)(F)F)C(F)(F)F InChI=1/C23H23F7N2O4S/c1-13-11-14(21(24,22(25,26)27)23(28,29)30)9-10-17(13)31-18(33)15-7-5-6-8-16(15)19(34)32-20(2,3)12-37(4,35)36/h5-11H,12H2,1-4H3,(H,31,33)(H,32,34) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Greece Flubendiamide 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide. 09Sep2013 2013 doi:10.2903/j.efsa.2013.3298
+Flubendiamide 272451-65-7 single chemical entity Component is a metabolite of the substance N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide Not in list C23H23F7N2O4S Cc2cc(ccc2NC(=O)c1ccccc1C(=O)NC(C)(C)CS(C)(=O)=O)C(F)(C(F)(F)F)C(F)(F)F InChI=1/C23H23F7N2O4S/c1-13-11-14(21(24,22(25,26)27)23(28,29)30)9-10-17(13)31-18(33)15-7-5-6-8-16(15)19(34)32-20(2,3)12-37(4,35)36/h5-11H,12H2,1-4H3,(H,31,33)(H,32,34) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Greece Flubendiamide 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide. 09Sep2013 2013 doi:10.2903/j.efsa.2013.3298
+Flubendiamide 272451-65-7 single chemical entity Component is a metabolite of the substance N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide Not in list C23H23F7N2O4S Cc2cc(ccc2NC(=O)c1ccccc1C(=O)NC(C)(C)CS(C)(=O)=O)C(F)(C(F)(F)F)C(F)(F)F InChI=1/C23H23F7N2O4S/c1-13-11-14(21(24,22(25,26)27)23(28,29)30)9-10-17(13)31-18(33)15-7-5-6-8-16(15)19(34)32-20(2,3)12-37(4,35)36/h5-11H,12H2,1-4H3,(H,31,33)(H,32,34) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Greece Flubendiamide 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide. 09Sep2013 2013 doi:10.2903/j.efsa.2013.3298
+Flubendiamide 272451-65-7 single chemical entity Component is a metabolite of the substance N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide Not in list C23H23F7N2O4S Cc2cc(ccc2NC(=O)c1ccccc1C(=O)NC(C)(C)CS(C)(=O)=O)C(F)(C(F)(F)F)C(F)(F)F InChI=1/C23H23F7N2O4S/c1-13-11-14(21(24,22(25,26)27)23(28,29)30)9-10-17(13)31-18(33)15-7-5-6-8-16(15)19(34)32-20(2,3)12-37(4,35)36/h5-11H,12H2,1-4H3,(H,31,33)(H,32,34) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Greece Flubendiamide 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide. 09Sep2013 2013 doi:10.2903/j.efsa.2013.3298
+Flubendiamide 272451-65-7 single chemical entity Component is a metabolite of the substance N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide Not in list C23H23F7N2O4S Cc2cc(ccc2NC(=O)c1ccccc1C(=O)NC(C)(C)CS(C)(=O)=O)C(F)(C(F)(F)F)C(F)(F)F InChI=1/C23H23F7N2O4S/c1-13-11-14(21(24,22(25,26)27)23(28,29)30)9-10-17(13)31-18(33)15-7-5-6-8-16(15)19(34)32-20(2,3)12-37(4,35)36/h5-11H,12H2,1-4H3,(H,31,33)(H,32,34) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Greece Flubendiamide 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide. 09Sep2013 2013 doi:10.2903/j.efsa.2013.3298
+Flubendiamide 272451-65-7 single chemical entity Component is a metabolite of the substance N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-3-hydroxy-N2-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-3-hydroxy-N2-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide Not in list C23H23F7N2O5S O=C(NC(C)(C)CS(C)(=O)=O)c1c(cccc1O)C(=O)Nc2ccc(cc2C)C(F)(C(F)(F)F)C(F)(F)F InChI=1/C23H23F7N2O5S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-15(12)31-18(34)14-6-5-7-16(33)17(14)19(35)32-20(2,3)11-38(4,36)37/h5-10,33H,11H2,1-4H3,(H,31,34)(H,32,35) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Greece Flubendiamide 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide. 09Sep2013 2013 doi:10.2903/j.efsa.2013.3298
+Flubendiamide 272451-65-7 single chemical entity Component is a metabolite of the substance N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-3-hydroxy-N2-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-3-hydroxy-N2-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide Not in list C23H23F7N2O5S O=C(NC(C)(C)CS(C)(=O)=O)c1c(cccc1O)C(=O)Nc2ccc(cc2C)C(F)(C(F)(F)F)C(F)(F)F InChI=1/C23H23F7N2O5S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-15(12)31-18(34)14-6-5-7-16(33)17(14)19(35)32-20(2,3)11-38(4,36)37/h5-10,33H,11H2,1-4H3,(H,31,34)(H,32,35) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Greece Flubendiamide 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide. 09Sep2013 2013 doi:10.2903/j.efsa.2013.3298
+Flubendiamide 272451-65-7 single chemical entity Component is a metabolite of the substance N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-3-hydroxy-N2-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-3-hydroxy-N2-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide Not in list C23H23F7N2O5S O=C(NC(C)(C)CS(C)(=O)=O)c1c(cccc1O)C(=O)Nc2ccc(cc2C)C(F)(C(F)(F)F)C(F)(F)F InChI=1/C23H23F7N2O5S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-15(12)31-18(34)14-6-5-7-16(33)17(14)19(35)32-20(2,3)11-38(4,36)37/h5-10,33H,11H2,1-4H3,(H,31,34)(H,32,35) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Greece Flubendiamide 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide. 09Sep2013 2013 doi:10.2903/j.efsa.2013.3298
+Flubendiamide 272451-65-7 single chemical entity Component is a metabolite of the substance N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-3-hydroxy-N2-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-3-hydroxy-N2-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide Not in list C23H23F7N2O5S O=C(NC(C)(C)CS(C)(=O)=O)c1c(cccc1O)C(=O)Nc2ccc(cc2C)C(F)(C(F)(F)F)C(F)(F)F InChI=1/C23H23F7N2O5S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-15(12)31-18(34)14-6-5-7-16(33)17(14)19(35)32-20(2,3)11-38(4,36)37/h5-10,33H,11H2,1-4H3,(H,31,34)(H,32,35) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Greece Flubendiamide 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide. 09Sep2013 2013 doi:10.2903/j.efsa.2013.3298
+Flubendiamide 272451-65-7 single chemical entity Component is a metabolite of the substance N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-3-hydroxy-N2-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-3-hydroxy-N2-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide Not in list C23H23F7N2O5S O=C(NC(C)(C)CS(C)(=O)=O)c1c(cccc1O)C(=O)Nc2ccc(cc2C)C(F)(C(F)(F)F)C(F)(F)F InChI=1/C23H23F7N2O5S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-15(12)31-18(34)14-6-5-7-16(33)17(14)19(35)32-20(2,3)11-38(4,36)37/h5-10,33H,11H2,1-4H3,(H,31,34)(H,32,35) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Greece Flubendiamide 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide. 09Sep2013 2013 doi:10.2903/j.efsa.2013.3298
+Flubendiamide 272451-65-7 single chemical entity Component is a metabolite of the substance N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-3-hydroxy-N2-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-3-hydroxy-N2-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide Not in list C23H23F7N2O5S O=C(NC(C)(C)CS(C)(=O)=O)c1c(cccc1O)C(=O)Nc2ccc(cc2C)C(F)(C(F)(F)F)C(F)(F)F InChI=1/C23H23F7N2O5S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-15(12)31-18(34)14-6-5-7-16(33)17(14)19(35)32-20(2,3)11-38(4,36)37/h5-10,33H,11H2,1-4H3,(H,31,34)(H,32,35) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Greece Flubendiamide 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide. 09Sep2013 2013 doi:10.2903/j.efsa.2013.3298
+Flubendiamide 272451-65-7 single chemical entity Component is a metabolite of the substance N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-3-hydroxy-N2-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-3-hydroxy-N2-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide Not in list C23H23F7N2O5S O=C(NC(C)(C)CS(C)(=O)=O)c1c(cccc1O)C(=O)Nc2ccc(cc2C)C(F)(C(F)(F)F)C(F)(F)F InChI=1/C23H23F7N2O5S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-15(12)31-18(34)14-6-5-7-16(33)17(14)19(35)32-20(2,3)11-38(4,36)37/h5-10,33H,11H2,1-4H3,(H,31,34)(H,32,35) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Greece Flubendiamide 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide. 09Sep2013 2013 doi:10.2903/j.efsa.2013.3298
+Flubendiamide 272451-65-7 single chemical entity Component is a metabolite of the substance N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-3-hydroxy-N2-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-3-hydroxy-N2-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide Not in list C23H23F7N2O5S O=C(NC(C)(C)CS(C)(=O)=O)c1c(cccc1O)C(=O)Nc2ccc(cc2C)C(F)(C(F)(F)F)C(F)(F)F InChI=1/C23H23F7N2O5S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-15(12)31-18(34)14-6-5-7-16(33)17(14)19(35)32-20(2,3)11-38(4,36)37/h5-10,33H,11H2,1-4H3,(H,31,34)(H,32,35) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Greece Flubendiamide 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide. 09Sep2013 2013 doi:10.2903/j.efsa.2013.3298
+Flubendiamide 272451-65-7 single chemical entity Component is a metabolite of the substance N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-3-hydroxy-N2-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-3-hydroxy-N2-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide Not in list C23H23F7N2O5S O=C(NC(C)(C)CS(C)(=O)=O)c1c(cccc1O)C(=O)Nc2ccc(cc2C)C(F)(C(F)(F)F)C(F)(F)F InChI=1/C23H23F7N2O5S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-15(12)31-18(34)14-6-5-7-16(33)17(14)19(35)32-20(2,3)11-38(4,36)37/h5-10,33H,11H2,1-4H3,(H,31,34)(H,32,35) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Greece Flubendiamide 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide. 09Sep2013 2013 doi:10.2903/j.efsa.2013.3298
+Flubendiamide 272451-65-7 single chemical entity Component is a metabolite of the substance N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-3-hydroxy-N2-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-3-hydroxy-N2-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide Not in list C23H23F7N2O5S O=C(NC(C)(C)CS(C)(=O)=O)c1c(cccc1O)C(=O)Nc2ccc(cc2C)C(F)(C(F)(F)F)C(F)(F)F InChI=1/C23H23F7N2O5S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-15(12)31-18(34)14-6-5-7-16(33)17(14)19(35)32-20(2,3)11-38(4,36)37/h5-10,33H,11H2,1-4H3,(H,31,34)(H,32,35) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Greece Flubendiamide 2008 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide. 09Sep2013 2013 doi:10.2903/j.efsa.2013.3298
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is identical to the substance Flonicamid 158062-67-0 N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide Flonicamid C9H6F3N3O O=C(NCC#N)c1cnccc1C(F)(F)F InChI=1S/C9H6F3N3O/c10-9(11,12)7-1-3-14-5-6(7)8(16)15-4-2-13/h1,3,5H,4H2,(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is identical to the substance Flonicamid 158062-67-0 N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide Flonicamid C9H6F3N3O O=C(NCC#N)c1cnccc1C(F)(F)F InChI=1S/C9H6F3N3O/c10-9(11,12)7-1-3-14-5-6(7)8(16)15-4-2-13/h1,3,5H,4H2,(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is identical to the substance Flonicamid 158062-67-0 N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide Flonicamid C9H6F3N3O O=C(NCC#N)c1cnccc1C(F)(F)F InChI=1S/C9H6F3N3O/c10-9(11,12)7-1-3-14-5-6(7)8(16)15-4-2-13/h1,3,5H,4H2,(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is identical to the substance Flonicamid 158062-67-0 N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide Flonicamid C9H6F3N3O O=C(NCC#N)c1cnccc1C(F)(F)F InChI=1S/C9H6F3N3O/c10-9(11,12)7-1-3-14-5-6(7)8(16)15-4-2-13/h1,3,5H,4H2,(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is identical to the substance Flonicamid 158062-67-0 N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide Flonicamid C9H6F3N3O O=C(NCC#N)c1cnccc1C(F)(F)F InChI=1S/C9H6F3N3O/c10-9(11,12)7-1-3-14-5-6(7)8(16)15-4-2-13/h1,3,5H,4H2,(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is identical to the substance Flonicamid 158062-67-0 N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide Flonicamid C9H6F3N3O O=C(NCC#N)c1cnccc1C(F)(F)F InChI=1S/C9H6F3N3O/c10-9(11,12)7-1-3-14-5-6(7)8(16)15-4-2-13/h1,3,5H,4H2,(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is identical to the substance Flonicamid 158062-67-0 N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide Flonicamid C9H6F3N3O O=C(NCC#N)c1cnccc1C(F)(F)F InChI=1S/C9H6F3N3O/c10-9(11,12)7-1-3-14-5-6(7)8(16)15-4-2-13/h1,3,5H,4H2,(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is identical to the substance Flonicamid 158062-67-0 N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide Flonicamid C9H6F3N3O O=C(NCC#N)c1cnccc1C(F)(F)F InChI=1S/C9H6F3N3O/c10-9(11,12)7-1-3-14-5-6(7)8(16)15-4-2-13/h1,3,5H,4H2,(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is identical to the substance Flonicamid 158062-67-0 N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide Flonicamid C9H6F3N3O O=C(NCC#N)c1cnccc1C(F)(F)F InChI=1S/C9H6F3N3O/c10-9(11,12)7-1-3-14-5-6(7)8(16)15-4-2-13/h1,3,5H,4H2,(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is identical to the substance Flonicamid 158062-67-0 N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide Flonicamid C9H6F3N3O O=C(NCC#N)c1cnccc1C(F)(F)F InChI=1S/C9H6F3N3O/c10-9(11,12)7-1-3-14-5-6(7)8(16)15-4-2-13/h1,3,5H,4H2,(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is identical to the substance Flonicamid 158062-67-0 N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide Flonicamid C9H6F3N3O O=C(NCC#N)c1cnccc1C(F)(F)F InChI=1S/C9H6F3N3O/c10-9(11,12)7-1-3-14-5-6(7)8(16)15-4-2-13/h1,3,5H,4H2,(H,15,16) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is identical to the substance Flonicamid 158062-67-0 N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide Flonicamid C9H6F3N3O O=C(NCC#N)c1cnccc1C(F)(F)F InChI=1S/C9H6F3N3O/c10-9(11,12)7-1-3-14-5-6(7)8(16)15-4-2-13/h1,3,5H,4H2,(H,15,16) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is identical to the substance Flonicamid 158062-67-0 N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide Flonicamid C9H6F3N3O O=C(NCC#N)c1cnccc1C(F)(F)F InChI=1S/C9H6F3N3O/c10-9(11,12)7-1-3-14-5-6(7)8(16)15-4-2-13/h1,3,5H,4H2,(H,15,16) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is identical to the substance Flonicamid 158062-67-0 N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide Flonicamid C9H6F3N3O O=C(NCC#N)c1cnccc1C(F)(F)F InChI=1S/C9H6F3N3O/c10-9(11,12)7-1-3-14-5-6(7)8(16)15-4-2-13/h1,3,5H,4H2,(H,15,16) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is identical to the substance Flonicamid 158062-67-0 N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide Flonicamid C9H6F3N3O O=C(NCC#N)c1cnccc1C(F)(F)F InChI=1S/C9H6F3N3O/c10-9(11,12)7-1-3-14-5-6(7)8(16)15-4-2-13/h1,3,5H,4H2,(H,15,16) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative small colonies RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is identical to the substance Flonicamid 158062-67-0 N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide Flonicamid C9H6F3N3O O=C(NCC#N)c1cnccc1C(F)(F)F InChI=1S/C9H6F3N3O/c10-9(11,12)7-1-3-14-5-6(7)8(16)15-4-2-13/h1,3,5H,4H2,(H,15,16) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative small colonies RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is identical to the substance Flonicamid 158062-67-0 N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide Flonicamid C9H6F3N3O O=C(NCC#N)c1cnccc1C(F)(F)F InChI=1S/C9H6F3N3O/c10-9(11,12)7-1-3-14-5-6(7)8(16)15-4-2-13/h1,3,5H,4H2,(H,15,16) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is identical to the substance Flonicamid 158062-67-0 N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide Flonicamid C9H6F3N3O O=C(NCC#N)c1cnccc1C(F)(F)F InChI=1S/C9H6F3N3O/c10-9(11,12)7-1-3-14-5-6(7)8(16)15-4-2-13/h1,3,5H,4H2,(H,15,16) organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Sprague-Dawley 5 Male oral: gavage 2.0000000000 h yes not applicable Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is identical to the substance Flonicamid 158062-67-0 N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide Flonicamid C9H6F3N3O O=C(NCC#N)c1cnccc1C(F)(F)F InChI=1S/C9H6F3N3O/c10-9(11,12)7-1-3-14-5-6(7)8(16)15-4-2-13/h1,3,5H,4H2,(H,15,16) organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Sprague-Dawley 5 Male oral: gavage 14.0000000000 h yes not applicable Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is identical to the substance Flonicamid 158062-67-0 N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide Flonicamid C9H6F3N3O O=C(NCC#N)c1cnccc1C(F)(F)F InChI=1S/C9H6F3N3O/c10-9(11,12)7-1-3-14-5-6(7)8(16)15-4-2-13/h1,3,5H,4H2,(H,15,16) organic compound Other Other DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo According to OECD Guideline 489 No Acceptable House mouse (as animal) ddy mouse 3 Male oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is identical to the substance Flonicamid 158062-67-0 N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide Flonicamid C9H6F3N3O O=C(NCC#N)c1cnccc1C(F)(F)F InChI=1S/C9H6F3N3O/c10-9(11,12)7-1-3-14-5-6(7)8(16)15-4-2-13/h1,3,5H,4H2,(H,15,16) organic compound Other Other DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo According to OECD Guideline 489 No Acceptable House mouse (as animal) ddy mouse 3 Male oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is identical to the substance Flonicamid 158062-67-0 N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide Flonicamid C9H6F3N3O O=C(NCC#N)c1cnccc1C(F)(F)F InChI=1S/C9H6F3N3O/c10-9(11,12)7-1-3-14-5-6(7)8(16)15-4-2-13/h1,3,5H,4H2,(H,15,16) organic compound Other Other DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo According to OECD Guideline 489 No Acceptable House mouse (as animal) ddy mouse 3 Male oral: unspecified 3.0000000000 h yes, concurrent vehicle not applicable Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is identical to the substance Flonicamid 158062-67-0 N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide Flonicamid C9H6F3N3O O=C(NCC#N)c1cnccc1C(F)(F)F InChI=1S/C9H6F3N3O/c10-9(11,12)7-1-3-14-5-6(7)8(16)15-4-2-13/h1,3,5H,4H2,(H,15,16) organic compound Other Other DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo According to OECD Guideline 489 No Acceptable House mouse (as animal) ddy mouse 3 Male oral: unspecified 3.0000000000 h yes, concurrent vehicle not applicable Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is identical to the substance Flonicamid 158062-67-0 N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide Flonicamid C9H6F3N3O O=C(NCC#N)c1cnccc1C(F)(F)F InChI=1S/C9H6F3N3O/c10-9(11,12)7-1-3-14-5-6(7)8(16)15-4-2-13/h1,3,5H,4H2,(H,15,16) organic compound Other Other DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo According to OECD Guideline 489 No Acceptable House mouse (as animal) ddy mouse 3 Male oral: unspecified 3.0000000000 h yes, concurrent vehicle not applicable Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is identical to the substance Flonicamid 158062-67-0 N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide Flonicamid C9H6F3N3O O=C(NCC#N)c1cnccc1C(F)(F)F InChI=1S/C9H6F3N3O/c10-9(11,12)7-1-3-14-5-6(7)8(16)15-4-2-13/h1,3,5H,4H2,(H,15,16) organic compound Other Other DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo According to OECD Guideline 489 No Acceptable House mouse (as animal) ddy mouse 3 Male oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is a metabolite of the substance 4-trifluoromethylnicotinic acid 623-902-1 158063-66-2 4-(trifluoromethyl)pyridine-3-carboxylic acid Not in list C7H4F3NO2 C1=CN=CC(=C1C(F)(F)F)C(=O)O InChI=1S/C7H4F3NO2/c8-7(9,10)5-1-2-11-3-4(5)6(12)13/h1-3H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is a metabolite of the substance 4-trifluoromethylnicotinic acid 623-902-1 158063-66-2 4-(trifluoromethyl)pyridine-3-carboxylic acid Not in list C7H4F3NO2 C1=CN=CC(=C1C(F)(F)F)C(=O)O InChI=1S/C7H4F3NO2/c8-7(9,10)5-1-2-11-3-4(5)6(12)13/h1-3H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is a metabolite of the substance 4-trifluoromethylnicotinic acid 623-902-1 158063-66-2 4-(trifluoromethyl)pyridine-3-carboxylic acid Not in list C7H4F3NO2 C1=CN=CC(=C1C(F)(F)F)C(=O)O InChI=1S/C7H4F3NO2/c8-7(9,10)5-1-2-11-3-4(5)6(12)13/h1-3H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is a metabolite of the substance 4-trifluoromethylnicotinic acid 623-902-1 158063-66-2 4-(trifluoromethyl)pyridine-3-carboxylic acid Not in list C7H4F3NO2 C1=CN=CC(=C1C(F)(F)F)C(=O)O InChI=1S/C7H4F3NO2/c8-7(9,10)5-1-2-11-3-4(5)6(12)13/h1-3H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is a metabolite of the substance 4-trifluoromethylnicotinic acid 623-902-1 158063-66-2 4-(trifluoromethyl)pyridine-3-carboxylic acid Not in list C7H4F3NO2 C1=CN=CC(=C1C(F)(F)F)C(=O)O InChI=1S/C7H4F3NO2/c8-7(9,10)5-1-2-11-3-4(5)6(12)13/h1-3H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is a metabolite of the substance 4-trifluoromethylnicotinic acid 623-902-1 158063-66-2 4-(trifluoromethyl)pyridine-3-carboxylic acid Not in list C7H4F3NO2 C1=CN=CC(=C1C(F)(F)F)C(=O)O InChI=1S/C7H4F3NO2/c8-7(9,10)5-1-2-11-3-4(5)6(12)13/h1-3H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is a metabolite of the substance 4-trifluoromethylnicotinic acid 623-902-1 158063-66-2 4-(trifluoromethyl)pyridine-3-carboxylic acid Not in list C7H4F3NO2 C1=CN=CC(=C1C(F)(F)F)C(=O)O InChI=1S/C7H4F3NO2/c8-7(9,10)5-1-2-11-3-4(5)6(12)13/h1-3H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is a metabolite of the substance 4-trifluoromethylnicotinic acid 623-902-1 158063-66-2 4-(trifluoromethyl)pyridine-3-carboxylic acid Not in list C7H4F3NO2 C1=CN=CC(=C1C(F)(F)F)C(=O)O InChI=1S/C7H4F3NO2/c8-7(9,10)5-1-2-11-3-4(5)6(12)13/h1-3H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is a metabolite of the substance 4-trifluoromethylnicotinic acid 623-902-1 158063-66-2 4-(trifluoromethyl)pyridine-3-carboxylic acid Not in list C7H4F3NO2 C1=CN=CC(=C1C(F)(F)F)C(=O)O InChI=1S/C7H4F3NO2/c8-7(9,10)5-1-2-11-3-4(5)6(12)13/h1-3H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is a metabolite of the substance 4-trifluoromethylnicotinic acid 623-902-1 158063-66-2 4-(trifluoromethyl)pyridine-3-carboxylic acid Not in list C7H4F3NO2 C1=CN=CC(=C1C(F)(F)F)C(=O)O InChI=1S/C7H4F3NO2/c8-7(9,10)5-1-2-11-3-4(5)6(12)13/h1-3H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is a metabolite of the substance 4-trifluoromethylnicotinamide 4-(trifluoromethyl)pyridine-3-carboxamide Not in list C7H5F3N2O C1=CN=CC(=C1C(F)(F)F)C(=O)N InChI=1S/C7H5F3N2O/c8-7(9,10)5-1-2-12-3-4(5)6(11)13/h1-3H,(H2,11,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is a metabolite of the substance 4-trifluoromethylnicotinamide 4-(trifluoromethyl)pyridine-3-carboxamide Not in list C7H5F3N2O C1=CN=CC(=C1C(F)(F)F)C(=O)N InChI=1S/C7H5F3N2O/c8-7(9,10)5-1-2-12-3-4(5)6(11)13/h1-3H,(H2,11,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is a metabolite of the substance 4-trifluoromethylnicotinamide 4-(trifluoromethyl)pyridine-3-carboxamide Not in list C7H5F3N2O C1=CN=CC(=C1C(F)(F)F)C(=O)N InChI=1S/C7H5F3N2O/c8-7(9,10)5-1-2-12-3-4(5)6(11)13/h1-3H,(H2,11,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is a metabolite of the substance 4-trifluoromethylnicotinamide 4-(trifluoromethyl)pyridine-3-carboxamide Not in list C7H5F3N2O C1=CN=CC(=C1C(F)(F)F)C(=O)N InChI=1S/C7H5F3N2O/c8-7(9,10)5-1-2-12-3-4(5)6(11)13/h1-3H,(H2,11,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is a metabolite of the substance 4-trifluoromethylnicotinamide 4-(trifluoromethyl)pyridine-3-carboxamide Not in list C7H5F3N2O C1=CN=CC(=C1C(F)(F)F)C(=O)N InChI=1S/C7H5F3N2O/c8-7(9,10)5-1-2-12-3-4(5)6(11)13/h1-3H,(H2,11,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is a metabolite of the substance 4-trifluoromethylnicotinamide 4-(trifluoromethyl)pyridine-3-carboxamide Not in list C7H5F3N2O C1=CN=CC(=C1C(F)(F)F)C(=O)N InChI=1S/C7H5F3N2O/c8-7(9,10)5-1-2-12-3-4(5)6(11)13/h1-3H,(H2,11,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is a metabolite of the substance 4-trifluoromethylnicotinamide 4-(trifluoromethyl)pyridine-3-carboxamide Not in list C7H5F3N2O C1=CN=CC(=C1C(F)(F)F)C(=O)N InChI=1S/C7H5F3N2O/c8-7(9,10)5-1-2-12-3-4(5)6(11)13/h1-3H,(H2,11,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is a metabolite of the substance 4-trifluoromethylnicotinamide 4-(trifluoromethyl)pyridine-3-carboxamide Not in list C7H5F3N2O C1=CN=CC(=C1C(F)(F)F)C(=O)N InChI=1S/C7H5F3N2O/c8-7(9,10)5-1-2-12-3-4(5)6(11)13/h1-3H,(H2,11,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is a metabolite of the substance 4-trifluoromethylnicotinamide 4-(trifluoromethyl)pyridine-3-carboxamide Not in list C7H5F3N2O C1=CN=CC(=C1C(F)(F)F)C(=O)N InChI=1S/C7H5F3N2O/c8-7(9,10)5-1-2-12-3-4(5)6(11)13/h1-3H,(H2,11,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is a metabolite of the substance 4-trifluoromethylnicotinamide 4-(trifluoromethyl)pyridine-3-carboxamide Not in list C7H5F3N2O C1=CN=CC(=C1C(F)(F)F)C(=O)N InChI=1S/C7H5F3N2O/c8-7(9,10)5-1-2-12-3-4(5)6(11)13/h1-3H,(H2,11,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is a metabolite of the substance N-(4-trifluoromethylnicotinoyl)glycine N-{[4-(trifluoromethyl)pyridin-3-yl]carbonyl}glycine Not in list C9H7F3N2O3 C1=CN=CC(=C1C(F)(F)F)C(=O)NCC(=O)O InChI=1S/C9H7F3N2O3/c10-9(11,12)6-1-2-13-3-5(6)8(17)14-4-7(15)16/h1-3H,4H2,(H,14,17)(H,15,16) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is a metabolite of the substance N-(4-trifluoromethylnicotinoyl)glycine N-{[4-(trifluoromethyl)pyridin-3-yl]carbonyl}glycine Not in list C9H7F3N2O3 C1=CN=CC(=C1C(F)(F)F)C(=O)NCC(=O)O InChI=1S/C9H7F3N2O3/c10-9(11,12)6-1-2-13-3-5(6)8(17)14-4-7(15)16/h1-3H,4H2,(H,14,17)(H,15,16) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is a metabolite of the substance N-(4-trifluoromethylnicotinoyl)glycine N-{[4-(trifluoromethyl)pyridin-3-yl]carbonyl}glycine Not in list C9H7F3N2O3 C1=CN=CC(=C1C(F)(F)F)C(=O)NCC(=O)O InChI=1S/C9H7F3N2O3/c10-9(11,12)6-1-2-13-3-5(6)8(17)14-4-7(15)16/h1-3H,4H2,(H,14,17)(H,15,16) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is a metabolite of the substance N-(4-trifluoromethylnicotinoyl)glycine N-{[4-(trifluoromethyl)pyridin-3-yl]carbonyl}glycine Not in list C9H7F3N2O3 C1=CN=CC(=C1C(F)(F)F)C(=O)NCC(=O)O InChI=1S/C9H7F3N2O3/c10-9(11,12)6-1-2-13-3-5(6)8(17)14-4-7(15)16/h1-3H,4H2,(H,14,17)(H,15,16) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is a metabolite of the substance N-(4-trifluoromethylnicotinoyl)glycine N-{[4-(trifluoromethyl)pyridin-3-yl]carbonyl}glycine Not in list C9H7F3N2O3 C1=CN=CC(=C1C(F)(F)F)C(=O)NCC(=O)O InChI=1S/C9H7F3N2O3/c10-9(11,12)6-1-2-13-3-5(6)8(17)14-4-7(15)16/h1-3H,4H2,(H,14,17)(H,15,16) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is a metabolite of the substance N-(4-trifluoromethylnicotinoyl)glycine N-{[4-(trifluoromethyl)pyridin-3-yl]carbonyl}glycine Not in list C9H7F3N2O3 C1=CN=CC(=C1C(F)(F)F)C(=O)NCC(=O)O InChI=1S/C9H7F3N2O3/c10-9(11,12)6-1-2-13-3-5(6)8(17)14-4-7(15)16/h1-3H,4H2,(H,14,17)(H,15,16) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is a metabolite of the substance N-(4-trifluoromethylnicotinoyl)glycine N-{[4-(trifluoromethyl)pyridin-3-yl]carbonyl}glycine Not in list C9H7F3N2O3 C1=CN=CC(=C1C(F)(F)F)C(=O)NCC(=O)O InChI=1S/C9H7F3N2O3/c10-9(11,12)6-1-2-13-3-5(6)8(17)14-4-7(15)16/h1-3H,4H2,(H,14,17)(H,15,16) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is a metabolite of the substance N-(4-trifluoromethylnicotinoyl)glycine N-{[4-(trifluoromethyl)pyridin-3-yl]carbonyl}glycine Not in list C9H7F3N2O3 C1=CN=CC(=C1C(F)(F)F)C(=O)NCC(=O)O InChI=1S/C9H7F3N2O3/c10-9(11,12)6-1-2-13-3-5(6)8(17)14-4-7(15)16/h1-3H,4H2,(H,14,17)(H,15,16) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is a metabolite of the substance N-(4-trifluoromethylnicotinoyl)glycine N-{[4-(trifluoromethyl)pyridin-3-yl]carbonyl}glycine Not in list C9H7F3N2O3 C1=CN=CC(=C1C(F)(F)F)C(=O)NCC(=O)O InChI=1S/C9H7F3N2O3/c10-9(11,12)6-1-2-13-3-5(6)8(17)14-4-7(15)16/h1-3H,4H2,(H,14,17)(H,15,16) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is a metabolite of the substance N-(4-trifluoromethylnicotinoyl)glycine N-{[4-(trifluoromethyl)pyridin-3-yl]carbonyl}glycine Not in list C9H7F3N2O3 C1=CN=CC(=C1C(F)(F)F)C(=O)NCC(=O)O InChI=1S/C9H7F3N2O3/c10-9(11,12)6-1-2-13-3-5(6)8(17)14-4-7(15)16/h1-3H,4H2,(H,14,17)(H,15,16) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is a metabolite of the substance N-(4-trifluoromethylnicotinoyl)glycinamide N-(2-amino-2-oxoethyl)-4-(trifluoromethyl)pyridine-3-carboxamide Not in list C9H8F3N3O2 O=C(NCC(N)=O)c1cnccc1C(F)(F)F InChI=1/C9H8F3N3O2/c10-9(11,12)6-1-2-14-3-5(6)8(17)15-4-7(13)16/h1-3H,4H2,(H2,13,16)(H,15,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is a metabolite of the substance N-(4-trifluoromethylnicotinoyl)glycinamide N-(2-amino-2-oxoethyl)-4-(trifluoromethyl)pyridine-3-carboxamide Not in list C9H8F3N3O2 O=C(NCC(N)=O)c1cnccc1C(F)(F)F InChI=1/C9H8F3N3O2/c10-9(11,12)6-1-2-14-3-5(6)8(17)15-4-7(13)16/h1-3H,4H2,(H2,13,16)(H,15,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is a metabolite of the substance N-(4-trifluoromethylnicotinoyl)glycinamide N-(2-amino-2-oxoethyl)-4-(trifluoromethyl)pyridine-3-carboxamide Not in list C9H8F3N3O2 O=C(NCC(N)=O)c1cnccc1C(F)(F)F InChI=1/C9H8F3N3O2/c10-9(11,12)6-1-2-14-3-5(6)8(17)15-4-7(13)16/h1-3H,4H2,(H2,13,16)(H,15,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is a metabolite of the substance N-(4-trifluoromethylnicotinoyl)glycinamide N-(2-amino-2-oxoethyl)-4-(trifluoromethyl)pyridine-3-carboxamide Not in list C9H8F3N3O2 O=C(NCC(N)=O)c1cnccc1C(F)(F)F InChI=1/C9H8F3N3O2/c10-9(11,12)6-1-2-14-3-5(6)8(17)15-4-7(13)16/h1-3H,4H2,(H2,13,16)(H,15,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is a metabolite of the substance N-(4-trifluoromethylnicotinoyl)glycinamide N-(2-amino-2-oxoethyl)-4-(trifluoromethyl)pyridine-3-carboxamide Not in list C9H8F3N3O2 O=C(NCC(N)=O)c1cnccc1C(F)(F)F InChI=1/C9H8F3N3O2/c10-9(11,12)6-1-2-14-3-5(6)8(17)15-4-7(13)16/h1-3H,4H2,(H2,13,16)(H,15,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is a metabolite of the substance N-(4-trifluoromethylnicotinoyl)glycinamide N-(2-amino-2-oxoethyl)-4-(trifluoromethyl)pyridine-3-carboxamide Not in list C9H8F3N3O2 O=C(NCC(N)=O)c1cnccc1C(F)(F)F InChI=1/C9H8F3N3O2/c10-9(11,12)6-1-2-14-3-5(6)8(17)15-4-7(13)16/h1-3H,4H2,(H2,13,16)(H,15,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is a metabolite of the substance N-(4-trifluoromethylnicotinoyl)glycinamide N-(2-amino-2-oxoethyl)-4-(trifluoromethyl)pyridine-3-carboxamide Not in list C9H8F3N3O2 O=C(NCC(N)=O)c1cnccc1C(F)(F)F InChI=1/C9H8F3N3O2/c10-9(11,12)6-1-2-14-3-5(6)8(17)15-4-7(13)16/h1-3H,4H2,(H2,13,16)(H,15,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is a metabolite of the substance N-(4-trifluoromethylnicotinoyl)glycinamide N-(2-amino-2-oxoethyl)-4-(trifluoromethyl)pyridine-3-carboxamide Not in list C9H8F3N3O2 O=C(NCC(N)=O)c1cnccc1C(F)(F)F InChI=1/C9H8F3N3O2/c10-9(11,12)6-1-2-14-3-5(6)8(17)15-4-7(13)16/h1-3H,4H2,(H2,13,16)(H,15,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is a metabolite of the substance N-(4-trifluoromethylnicotinoyl)glycinamide N-(2-amino-2-oxoethyl)-4-(trifluoromethyl)pyridine-3-carboxamide Not in list C9H8F3N3O2 O=C(NCC(N)=O)c1cnccc1C(F)(F)F InChI=1/C9H8F3N3O2/c10-9(11,12)6-1-2-14-3-5(6)8(17)15-4-7(13)16/h1-3H,4H2,(H2,13,16)(H,15,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is a metabolite of the substance N-(4-trifluoromethylnicotinoyl)glycinamide N-(2-amino-2-oxoethyl)-4-(trifluoromethyl)pyridine-3-carboxamide Not in list C9H8F3N3O2 O=C(NCC(N)=O)c1cnccc1C(F)(F)F InChI=1/C9H8F3N3O2/c10-9(11,12)6-1-2-14-3-5(6)8(17)15-4-7(13)16/h1-3H,4H2,(H2,13,16)(H,15,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is a metabolite of the substance 6-hydroxy-4-trifluoromethylnicotinic acid 6-hydroxy-4-(trifluoromethyl)pyridine-3-carboxylic acid Not in list C7H4F3NO3 FC(F)(F)c1cc(O)ncc1C(O)=O InChI=1/C7H4F3NO3/c8-7(9,10)4-1-5(12)11-2-3(4)6(13)14/h1-2H,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is a metabolite of the substance 6-hydroxy-4-trifluoromethylnicotinic acid 6-hydroxy-4-(trifluoromethyl)pyridine-3-carboxylic acid Not in list C7H4F3NO3 FC(F)(F)c1cc(O)ncc1C(O)=O InChI=1/C7H4F3NO3/c8-7(9,10)4-1-5(12)11-2-3(4)6(13)14/h1-2H,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is a metabolite of the substance 6-hydroxy-4-trifluoromethylnicotinic acid 6-hydroxy-4-(trifluoromethyl)pyridine-3-carboxylic acid Not in list C7H4F3NO3 FC(F)(F)c1cc(O)ncc1C(O)=O InChI=1/C7H4F3NO3/c8-7(9,10)4-1-5(12)11-2-3(4)6(13)14/h1-2H,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is a metabolite of the substance 6-hydroxy-4-trifluoromethylnicotinic acid 6-hydroxy-4-(trifluoromethyl)pyridine-3-carboxylic acid Not in list C7H4F3NO3 FC(F)(F)c1cc(O)ncc1C(O)=O InChI=1/C7H4F3NO3/c8-7(9,10)4-1-5(12)11-2-3(4)6(13)14/h1-2H,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is a metabolite of the substance 6-hydroxy-4-trifluoromethylnicotinic acid 6-hydroxy-4-(trifluoromethyl)pyridine-3-carboxylic acid Not in list C7H4F3NO3 FC(F)(F)c1cc(O)ncc1C(O)=O InChI=1/C7H4F3NO3/c8-7(9,10)4-1-5(12)11-2-3(4)6(13)14/h1-2H,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is a metabolite of the substance 6-hydroxy-4-trifluoromethylnicotinic acid 6-hydroxy-4-(trifluoromethyl)pyridine-3-carboxylic acid Not in list C7H4F3NO3 FC(F)(F)c1cc(O)ncc1C(O)=O InChI=1/C7H4F3NO3/c8-7(9,10)4-1-5(12)11-2-3(4)6(13)14/h1-2H,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is a metabolite of the substance 6-hydroxy-4-trifluoromethylnicotinic acid 6-hydroxy-4-(trifluoromethyl)pyridine-3-carboxylic acid Not in list C7H4F3NO3 FC(F)(F)c1cc(O)ncc1C(O)=O InChI=1/C7H4F3NO3/c8-7(9,10)4-1-5(12)11-2-3(4)6(13)14/h1-2H,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is a metabolite of the substance 6-hydroxy-4-trifluoromethylnicotinic acid 6-hydroxy-4-(trifluoromethyl)pyridine-3-carboxylic acid Not in list C7H4F3NO3 FC(F)(F)c1cc(O)ncc1C(O)=O InChI=1/C7H4F3NO3/c8-7(9,10)4-1-5(12)11-2-3(4)6(13)14/h1-2H,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is a metabolite of the substance 6-hydroxy-4-trifluoromethylnicotinic acid 6-hydroxy-4-(trifluoromethyl)pyridine-3-carboxylic acid Not in list C7H4F3NO3 FC(F)(F)c1cc(O)ncc1C(O)=O InChI=1/C7H4F3NO3/c8-7(9,10)4-1-5(12)11-2-3(4)6(13)14/h1-2H,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Flonicamid 605-127-0 158062-67-0 single chemical entity Component is a metabolite of the substance 6-hydroxy-4-trifluoromethylnicotinic acid 6-hydroxy-4-(trifluoromethyl)pyridine-3-carboxylic acid Not in list C7H4F3NO3 FC(F)(F)c1cc(O)ncc1C(O)=O InChI=1/C7H4F3NO3/c8-7(9,10)4-1-5(12)11-2-3(4)6(13)14/h1-2H,(H,11,12)(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: France Flonicamid 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid 07May2010 2010 doi:10.2903/j.efsa.2010.1445
+Fluoxastrobin 609-207-6 361377-29-9 single chemical entity Component is identical to the substance Fluoxastrobin 609-207-6 361377-29-9 (E)-1-[2-[6-(2-chlorophenoxy)-5-fluoropyrimidin-4-yl]oxyphenyl]-1-(5,6-dihydro-1,4,2-dioxazin-3-yl)-N-methoxymethanimine Fluoxastrobin Fluoxastrobin CO/N=C(\C1=CC=CC=C1OC2=C(C(=NC=N2)OC3=CC=CC=C3Cl)F)/C4=NOCCO4 InChI=1S/C21H16ClFN4O5/c1-28-26-18(21-27-30-11-10-29-21)13-6-2-4-8-15(13)31-19-17(23)20(25-12-24-19)32-16-9-5-3-7-14(16)22/h2-9,12H,10-11H2,1H3/b26-18+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fluoxastrobin 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.102r
+Fluoxastrobin 609-207-6 361377-29-9 single chemical entity Component is identical to the substance Fluoxastrobin 609-207-6 361377-29-9 (E)-1-[2-[6-(2-chlorophenoxy)-5-fluoropyrimidin-4-yl]oxyphenyl]-1-(5,6-dihydro-1,4,2-dioxazin-3-yl)-N-methoxymethanimine Fluoxastrobin Fluoxastrobin CO/N=C(\C1=CC=CC=C1OC2=C(C(=NC=N2)OC3=CC=CC=C3Cl)F)/C4=NOCCO4 InChI=1S/C21H16ClFN4O5/c1-28-26-18(21-27-30-11-10-29-21)13-6-2-4-8-15(13)31-19-17(23)20(25-12-24-19)32-16-9-5-3-7-14(16)22/h2-9,12H,10-11H2,1H3/b26-18+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluoxastrobin 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.102r
+Fluoxastrobin 609-207-6 361377-29-9 single chemical entity Component is identical to the substance Fluoxastrobin 609-207-6 361377-29-9 (E)-1-[2-[6-(2-chlorophenoxy)-5-fluoropyrimidin-4-yl]oxyphenyl]-1-(5,6-dihydro-1,4,2-dioxazin-3-yl)-N-methoxymethanimine Fluoxastrobin Fluoxastrobin CO/N=C(\C1=CC=CC=C1OC2=C(C(=NC=N2)OC3=CC=CC=C3Cl)F)/C4=NOCCO4 InChI=1S/C21H16ClFN4O5/c1-28-26-18(21-27-30-11-10-29-21)13-6-2-4-8-15(13)31-19-17(23)20(25-12-24-19)32-16-9-5-3-7-14(16)22/h2-9,12H,10-11H2,1H3/b26-18+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fluoxastrobin 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.102r
+Fluoxastrobin 609-207-6 361377-29-9 single chemical entity Component is identical to the substance Fluoxastrobin 609-207-6 361377-29-9 (E)-1-[2-[6-(2-chlorophenoxy)-5-fluoropyrimidin-4-yl]oxyphenyl]-1-(5,6-dihydro-1,4,2-dioxazin-3-yl)-N-methoxymethanimine Fluoxastrobin Fluoxastrobin CO/N=C(\C1=CC=CC=C1OC2=C(C(=NC=N2)OC3=CC=CC=C3Cl)F)/C4=NOCCO4 InChI=1S/C21H16ClFN4O5/c1-28-26-18(21-27-30-11-10-29-21)13-6-2-4-8-15(13)31-19-17(23)20(25-12-24-19)32-16-9-5-3-7-14(16)22/h2-9,12H,10-11H2,1H3/b26-18+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluoxastrobin 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.102r
+Fluoxastrobin 609-207-6 361377-29-9 single chemical entity Component is identical to the substance Fluoxastrobin 609-207-6 361377-29-9 (E)-1-[2-[6-(2-chlorophenoxy)-5-fluoropyrimidin-4-yl]oxyphenyl]-1-(5,6-dihydro-1,4,2-dioxazin-3-yl)-N-methoxymethanimine Fluoxastrobin Fluoxastrobin CO/N=C(\C1=CC=CC=C1OC2=C(C(=NC=N2)OC3=CC=CC=C3Cl)F)/C4=NOCCO4 InChI=1S/C21H16ClFN4O5/c1-28-26-18(21-27-30-11-10-29-21)13-6-2-4-8-15(13)31-19-17(23)20(25-12-24-19)32-16-9-5-3-7-14(16)22/h2-9,12H,10-11H2,1H3/b26-18+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fluoxastrobin 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.102r
+Fluoxastrobin 609-207-6 361377-29-9 single chemical entity Component is identical to the substance Fluoxastrobin 609-207-6 361377-29-9 (E)-1-[2-[6-(2-chlorophenoxy)-5-fluoropyrimidin-4-yl]oxyphenyl]-1-(5,6-dihydro-1,4,2-dioxazin-3-yl)-N-methoxymethanimine Fluoxastrobin Fluoxastrobin CO/N=C(\C1=CC=CC=C1OC2=C(C(=NC=N2)OC3=CC=CC=C3Cl)F)/C4=NOCCO4 InChI=1S/C21H16ClFN4O5/c1-28-26-18(21-27-30-11-10-29-21)13-6-2-4-8-15(13)31-19-17(23)20(25-12-24-19)32-16-9-5-3-7-14(16)22/h2-9,12H,10-11H2,1H3/b26-18+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fluoxastrobin 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.102r
+Fluoxastrobin 609-207-6 361377-29-9 single chemical entity Component is identical to the substance Fluoxastrobin 609-207-6 361377-29-9 (E)-1-[2-[6-(2-chlorophenoxy)-5-fluoropyrimidin-4-yl]oxyphenyl]-1-(5,6-dihydro-1,4,2-dioxazin-3-yl)-N-methoxymethanimine Fluoxastrobin Fluoxastrobin CO/N=C(\C1=CC=CC=C1OC2=C(C(=NC=N2)OC3=CC=CC=C3Cl)F)/C4=NOCCO4 InChI=1S/C21H16ClFN4O5/c1-28-26-18(21-27-30-11-10-29-21)13-6-2-4-8-15(13)31-19-17(23)20(25-12-24-19)32-16-9-5-3-7-14(16)22/h2-9,12H,10-11H2,1H3/b26-18+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluoxastrobin 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.102r
+Fluoxastrobin 609-207-6 361377-29-9 single chemical entity Component is identical to the substance Fluoxastrobin 609-207-6 361377-29-9 (E)-1-[2-[6-(2-chlorophenoxy)-5-fluoropyrimidin-4-yl]oxyphenyl]-1-(5,6-dihydro-1,4,2-dioxazin-3-yl)-N-methoxymethanimine Fluoxastrobin Fluoxastrobin CO/N=C(\C1=CC=CC=C1OC2=C(C(=NC=N2)OC3=CC=CC=C3Cl)F)/C4=NOCCO4 InChI=1S/C21H16ClFN4O5/c1-28-26-18(21-27-30-11-10-29-21)13-6-2-4-8-15(13)31-19-17(23)20(25-12-24-19)32-16-9-5-3-7-14(16)22/h2-9,12H,10-11H2,1H3/b26-18+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluoxastrobin 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.102r
+Fluoxastrobin 609-207-6 361377-29-9 single chemical entity Component is identical to the substance Fluoxastrobin 609-207-6 361377-29-9 (E)-1-[2-[6-(2-chlorophenoxy)-5-fluoropyrimidin-4-yl]oxyphenyl]-1-(5,6-dihydro-1,4,2-dioxazin-3-yl)-N-methoxymethanimine Fluoxastrobin Fluoxastrobin CO/N=C(\C1=CC=CC=C1OC2=C(C(=NC=N2)OC3=CC=CC=C3Cl)F)/C4=NOCCO4 InChI=1S/C21H16ClFN4O5/c1-28-26-18(21-27-30-11-10-29-21)13-6-2-4-8-15(13)31-19-17(23)20(25-12-24-19)32-16-9-5-3-7-14(16)22/h2-9,12H,10-11H2,1H3/b26-18+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fluoxastrobin 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.102r
+Fluoxastrobin 609-207-6 361377-29-9 single chemical entity Component is identical to the substance Fluoxastrobin 609-207-6 361377-29-9 (E)-1-[2-[6-(2-chlorophenoxy)-5-fluoropyrimidin-4-yl]oxyphenyl]-1-(5,6-dihydro-1,4,2-dioxazin-3-yl)-N-methoxymethanimine Fluoxastrobin Fluoxastrobin CO/N=C(\C1=CC=CC=C1OC2=C(C(=NC=N2)OC3=CC=CC=C3Cl)F)/C4=NOCCO4 InChI=1S/C21H16ClFN4O5/c1-28-26-18(21-27-30-11-10-29-21)13-6-2-4-8-15(13)31-19-17(23)20(25-12-24-19)32-16-9-5-3-7-14(16)22/h2-9,12H,10-11H2,1H3/b26-18+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluoxastrobin 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.102r
+Fluoxastrobin 609-207-6 361377-29-9 single chemical entity Component is identical to the substance Fluoxastrobin 609-207-6 361377-29-9 (E)-1-[2-[6-(2-chlorophenoxy)-5-fluoropyrimidin-4-yl]oxyphenyl]-1-(5,6-dihydro-1,4,2-dioxazin-3-yl)-N-methoxymethanimine Fluoxastrobin Fluoxastrobin CO/N=C(\C1=CC=CC=C1OC2=C(C(=NC=N2)OC3=CC=CC=C3Cl)F)/C4=NOCCO4 InChI=1S/C21H16ClFN4O5/c1-28-26-18(21-27-30-11-10-29-21)13-6-2-4-8-15(13)31-19-17(23)20(25-12-24-19)32-16-9-5-3-7-14(16)22/h2-9,12H,10-11H2,1H3/b26-18+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluoxastrobin 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.102r
+Fluoxastrobin 609-207-6 361377-29-9 single chemical entity Component is identical to the substance Fluoxastrobin 609-207-6 361377-29-9 (E)-1-[2-[6-(2-chlorophenoxy)-5-fluoropyrimidin-4-yl]oxyphenyl]-1-(5,6-dihydro-1,4,2-dioxazin-3-yl)-N-methoxymethanimine Fluoxastrobin Fluoxastrobin CO/N=C(\C1=CC=CC=C1OC2=C(C(=NC=N2)OC3=CC=CC=C3Cl)F)/C4=NOCCO4 InChI=1S/C21H16ClFN4O5/c1-28-26-18(21-27-30-11-10-29-21)13-6-2-4-8-15(13)31-19-17(23)20(25-12-24-19)32-16-9-5-3-7-14(16)22/h2-9,12H,10-11H2,1H3/b26-18+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluoxastrobin 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.102r
+Fluoxastrobin 609-207-6 361377-29-9 single chemical entity Component is identical to the substance Fluoxastrobin 609-207-6 361377-29-9 (E)-1-[2-[6-(2-chlorophenoxy)-5-fluoropyrimidin-4-yl]oxyphenyl]-1-(5,6-dihydro-1,4,2-dioxazin-3-yl)-N-methoxymethanimine Fluoxastrobin Fluoxastrobin CO/N=C(\C1=CC=CC=C1OC2=C(C(=NC=N2)OC3=CC=CC=C3Cl)F)/C4=NOCCO4 InChI=1S/C21H16ClFN4O5/c1-28-26-18(21-27-30-11-10-29-21)13-6-2-4-8-15(13)31-19-17(23)20(25-12-24-19)32-16-9-5-3-7-14(16)22/h2-9,12H,10-11H2,1H3/b26-18+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluoxastrobin 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.102r
+Fluoxastrobin 609-207-6 361377-29-9 single chemical entity Component is identical to the substance Fluoxastrobin 609-207-6 361377-29-9 (E)-1-[2-[6-(2-chlorophenoxy)-5-fluoropyrimidin-4-yl]oxyphenyl]-1-(5,6-dihydro-1,4,2-dioxazin-3-yl)-N-methoxymethanimine Fluoxastrobin Fluoxastrobin CO/N=C(\C1=CC=CC=C1OC2=C(C(=NC=N2)OC3=CC=CC=C3Cl)F)/C4=NOCCO4 InChI=1S/C21H16ClFN4O5/c1-28-26-18(21-27-30-11-10-29-21)13-6-2-4-8-15(13)31-19-17(23)20(25-12-24-19)32-16-9-5-3-7-14(16)22/h2-9,12H,10-11H2,1H3/b26-18+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluoxastrobin 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.102r
+Fluoxastrobin 609-207-6 361377-29-9 single chemical entity Component is identical to the substance Fluoxastrobin 609-207-6 361377-29-9 (E)-1-[2-[6-(2-chlorophenoxy)-5-fluoropyrimidin-4-yl]oxyphenyl]-1-(5,6-dihydro-1,4,2-dioxazin-3-yl)-N-methoxymethanimine Fluoxastrobin Fluoxastrobin CO/N=C(\C1=CC=CC=C1OC2=C(C(=NC=N2)OC3=CC=CC=C3Cl)F)/C4=NOCCO4 InChI=1S/C21H16ClFN4O5/c1-28-26-18(21-27-30-11-10-29-21)13-6-2-4-8-15(13)31-19-17(23)20(25-12-24-19)32-16-9-5-3-7-14(16)22/h2-9,12H,10-11H2,1H3/b26-18+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fluoxastrobin 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.102r
+Fluoxastrobin 609-207-6 361377-29-9 single chemical entity Component is identical to the substance Fluoxastrobin 609-207-6 361377-29-9 (E)-1-[2-[6-(2-chlorophenoxy)-5-fluoropyrimidin-4-yl]oxyphenyl]-1-(5,6-dihydro-1,4,2-dioxazin-3-yl)-N-methoxymethanimine Fluoxastrobin Fluoxastrobin CO/N=C(\C1=CC=CC=C1OC2=C(C(=NC=N2)OC3=CC=CC=C3Cl)F)/C4=NOCCO4 InChI=1S/C21H16ClFN4O5/c1-28-26-18(21-27-30-11-10-29-21)13-6-2-4-8-15(13)31-19-17(23)20(25-12-24-19)32-16-9-5-3-7-14(16)22/h2-9,12H,10-11H2,1H3/b26-18+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluoxastrobin 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.102r
+Fluoxastrobin 609-207-6 361377-29-9 single chemical entity Component is identical to the substance Fluoxastrobin 609-207-6 361377-29-9 (E)-1-[2-[6-(2-chlorophenoxy)-5-fluoropyrimidin-4-yl]oxyphenyl]-1-(5,6-dihydro-1,4,2-dioxazin-3-yl)-N-methoxymethanimine Fluoxastrobin Fluoxastrobin CO/N=C(\C1=CC=CC=C1OC2=C(C(=NC=N2)OC3=CC=CC=C3Cl)F)/C4=NOCCO4 InChI=1S/C21H16ClFN4O5/c1-28-26-18(21-27-30-11-10-29-21)13-6-2-4-8-15(13)31-19-17(23)20(25-12-24-19)32-16-9-5-3-7-14(16)22/h2-9,12H,10-11H2,1H3/b26-18+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fluoxastrobin 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.102r
+Fluoxastrobin 609-207-6 361377-29-9 single chemical entity Component is identical to the substance Fluoxastrobin 609-207-6 361377-29-9 (E)-1-[2-[6-(2-chlorophenoxy)-5-fluoropyrimidin-4-yl]oxyphenyl]-1-(5,6-dihydro-1,4,2-dioxazin-3-yl)-N-methoxymethanimine Fluoxastrobin Fluoxastrobin CO/N=C(\C1=CC=CC=C1OC2=C(C(=NC=N2)OC3=CC=CC=C3Cl)F)/C4=NOCCO4 InChI=1S/C21H16ClFN4O5/c1-28-26-18(21-27-30-11-10-29-21)13-6-2-4-8-15(13)31-19-17(23)20(25-12-24-19)32-16-9-5-3-7-14(16)22/h2-9,12H,10-11H2,1H3/b26-18+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fluoxastrobin 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.102r
+Fluoxastrobin 609-207-6 361377-29-9 single chemical entity Component is identical to the substance Fluoxastrobin 609-207-6 361377-29-9 (E)-1-[2-[6-(2-chlorophenoxy)-5-fluoropyrimidin-4-yl]oxyphenyl]-1-(5,6-dihydro-1,4,2-dioxazin-3-yl)-N-methoxymethanimine Fluoxastrobin Fluoxastrobin CO/N=C(\C1=CC=CC=C1OC2=C(C(=NC=N2)OC3=CC=CC=C3Cl)F)/C4=NOCCO4 InChI=1S/C21H16ClFN4O5/c1-28-26-18(21-27-30-11-10-29-21)13-6-2-4-8-15(13)31-19-17(23)20(25-12-24-19)32-16-9-5-3-7-14(16)22/h2-9,12H,10-11H2,1H3/b26-18+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fluoxastrobin 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.102r
+Fluoxastrobin 609-207-6 361377-29-9 single chemical entity Component is identical to the substance Fluoxastrobin 609-207-6 361377-29-9 (E)-1-[2-[6-(2-chlorophenoxy)-5-fluoropyrimidin-4-yl]oxyphenyl]-1-(5,6-dihydro-1,4,2-dioxazin-3-yl)-N-methoxymethanimine Fluoxastrobin Fluoxastrobin CO/N=C(\C1=CC=CC=C1OC2=C(C(=NC=N2)OC3=CC=CC=C3Cl)F)/C4=NOCCO4 InChI=1S/C21H16ClFN4O5/c1-28-26-18(21-27-30-11-10-29-21)13-6-2-4-8-15(13)31-19-17(23)20(25-12-24-19)32-16-9-5-3-7-14(16)22/h2-9,12H,10-11H2,1H3/b26-18+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fluoxastrobin 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.102r
+Fluoxastrobin 609-207-6 361377-29-9 single chemical entity Component is identical to the substance Fluoxastrobin 609-207-6 361377-29-9 (E)-1-[2-[6-(2-chlorophenoxy)-5-fluoropyrimidin-4-yl]oxyphenyl]-1-(5,6-dihydro-1,4,2-dioxazin-3-yl)-N-methoxymethanimine Fluoxastrobin Fluoxastrobin CO/N=C(\C1=CC=CC=C1OC2=C(C(=NC=N2)OC3=CC=CC=C3Cl)F)/C4=NOCCO4 InChI=1S/C21H16ClFN4O5/c1-28-26-18(21-27-30-11-10-29-21)13-6-2-4-8-15(13)31-19-17(23)20(25-12-24-19)32-16-9-5-3-7-14(16)22/h2-9,12H,10-11H2,1H3/b26-18+ organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Negative RMS: The United Kingdom Fluoxastrobin 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.102r
+Fluoxastrobin 609-207-6 361377-29-9 single chemical entity Component is identical to the substance Fluoxastrobin 609-207-6 361377-29-9 (E)-1-[2-[6-(2-chlorophenoxy)-5-fluoropyrimidin-4-yl]oxyphenyl]-1-(5,6-dihydro-1,4,2-dioxazin-3-yl)-N-methoxymethanimine Fluoxastrobin Fluoxastrobin CO/N=C(\C1=CC=CC=C1OC2=C(C(=NC=N2)OC3=CC=CC=C3Cl)F)/C4=NOCCO4 InChI=1S/C21H16ClFN4O5/c1-28-26-18(21-27-30-11-10-29-21)13-6-2-4-8-15(13)31-19-17(23)20(25-12-24-19)32-16-9-5-3-7-14(16)22/h2-9,12H,10-11H2,1H3/b26-18+ organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: The United Kingdom Fluoxastrobin 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.102r
+Fluoxastrobin 609-207-6 361377-29-9 single chemical entity Component is identical to the substance Fluoxastrobin 609-207-6 361377-29-9 (E)-1-[2-[6-(2-chlorophenoxy)-5-fluoropyrimidin-4-yl]oxyphenyl]-1-(5,6-dihydro-1,4,2-dioxazin-3-yl)-N-methoxymethanimine Fluoxastrobin Fluoxastrobin CO/N=C(\C1=CC=CC=C1OC2=C(C(=NC=N2)OC3=CC=CC=C3Cl)F)/C4=NOCCO4 InChI=1S/C21H16ClFN4O5/c1-28-26-18(21-27-30-11-10-29-21)13-6-2-4-8-15(13)31-19-17(23)20(25-12-24-19)32-16-9-5-3-7-14(16)22/h2-9,12H,10-11H2,1H3/b26-18+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: The United Kingdom Fluoxastrobin 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.102r
+Fluoxastrobin 609-207-6 361377-29-9 single chemical entity Component is identical to the substance Fluoxastrobin 609-207-6 361377-29-9 (E)-1-[2-[6-(2-chlorophenoxy)-5-fluoropyrimidin-4-yl]oxyphenyl]-1-(5,6-dihydro-1,4,2-dioxazin-3-yl)-N-methoxymethanimine Fluoxastrobin Fluoxastrobin CO/N=C(\C1=CC=CC=C1OC2=C(C(=NC=N2)OC3=CC=CC=C3Cl)F)/C4=NOCCO4 InChI=1S/C21H16ClFN4O5/c1-28-26-18(21-27-30-11-10-29-21)13-6-2-4-8-15(13)31-19-17(23)20(25-12-24-19)32-16-9-5-3-7-14(16)22/h2-9,12H,10-11H2,1H3/b26-18+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Negative RMS: The United Kingdom Fluoxastrobin 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.102r
+Fluoxastrobin 609-207-6 361377-29-9 single chemical entity Component is identical to the substance Fluoxastrobin 609-207-6 361377-29-9 (E)-1-[2-[6-(2-chlorophenoxy)-5-fluoropyrimidin-4-yl]oxyphenyl]-1-(5,6-dihydro-1,4,2-dioxazin-3-yl)-N-methoxymethanimine Fluoxastrobin Fluoxastrobin CO/N=C(\C1=CC=CC=C1OC2=C(C(=NC=N2)OC3=CC=CC=C3Cl)F)/C4=NOCCO4 InChI=1S/C21H16ClFN4O5/c1-28-26-18(21-27-30-11-10-29-21)13-6-2-4-8-15(13)31-19-17(23)20(25-12-24-19)32-16-9-5-3-7-14(16)22/h2-9,12H,10-11H2,1H3/b26-18+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: The United Kingdom Fluoxastrobin 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.102r
+Fluoxastrobin 609-207-6 361377-29-9 single chemical entity Component is identical to the substance Fluoxastrobin 609-207-6 361377-29-9 (E)-1-[2-[6-(2-chlorophenoxy)-5-fluoropyrimidin-4-yl]oxyphenyl]-1-(5,6-dihydro-1,4,2-dioxazin-3-yl)-N-methoxymethanimine Fluoxastrobin Fluoxastrobin CO/N=C(\C1=CC=CC=C1OC2=C(C(=NC=N2)OC3=CC=CC=C3Cl)F)/C4=NOCCO4 InChI=1S/C21H16ClFN4O5/c1-28-26-18(21-27-30-11-10-29-21)13-6-2-4-8-15(13)31-19-17(23)20(25-12-24-19)32-16-9-5-3-7-14(16)22/h2-9,12H,10-11H2,1H3/b26-18+ organic compound PubChem isomeric SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Negative RMS: The United Kingdom Fluoxastrobin 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.102r
+Fluoxastrobin 609-207-6 361377-29-9 single chemical entity Component is identical to the substance Fluoxastrobin 609-207-6 361377-29-9 (E)-1-[2-[6-(2-chlorophenoxy)-5-fluoropyrimidin-4-yl]oxyphenyl]-1-(5,6-dihydro-1,4,2-dioxazin-3-yl)-N-methoxymethanimine Fluoxastrobin Fluoxastrobin CO/N=C(\C1=CC=CC=C1OC2=C(C(=NC=N2)OC3=CC=CC=C3Cl)F)/C4=NOCCO4 InChI=1S/C21H16ClFN4O5/c1-28-26-18(21-27-30-11-10-29-21)13-6-2-4-8-15(13)31-19-17(23)20(25-12-24-19)32-16-9-5-3-7-14(16)22/h2-9,12H,10-11H2,1H3/b26-18+ organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 5 Male intraperitoneal 24.0000000000 h yes not applicable Negative indirect evidence-systemic toxicity RMS: The United Kingdom Fluoxastrobin 2003 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.102r
+Fluoxastrobin 609-207-6 361377-29-9 single chemical entity Component is a metabolite of the substance HEC5725-E-des-chlorophenyl (E)-5,6-dihydro-1,4,2-dioxazin-3-yl{2-[(5-fluoro-6-hydroxypyrimidin-4-yl)oxy]phenyl}methanone O-methyloxime Not in list C15H13FN4O5 Fc3c(O)ncnc3Oc2ccccc2C(=N\OC)/C=1OCCON=1 InChI=1/C15H13FN4O5/c1-22-19-12(15-20-24-7-6-23-15)9-4-2-3-5-10(9)25-14-11(16)13(21)17-8-18-14/h2-5,8H,6-7H2,1H3,(H,17,18,21)/b19-12+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluoxastrobin (Final addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.102r
+Fluoxastrobin 609-207-6 361377-29-9 single chemical entity Component is a metabolite of the substance HEC5725-E-des-chlorophenyl (E)-5,6-dihydro-1,4,2-dioxazin-3-yl{2-[(5-fluoro-6-hydroxypyrimidin-4-yl)oxy]phenyl}methanone O-methyloxime Not in list C15H13FN4O5 Fc3c(O)ncnc3Oc2ccccc2C(=N\OC)/C=1OCCON=1 InChI=1/C15H13FN4O5/c1-22-19-12(15-20-24-7-6-23-15)9-4-2-3-5-10(9)25-14-11(16)13(21)17-8-18-14/h2-5,8H,6-7H2,1H3,(H,17,18,21)/b19-12+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluoxastrobin (Final addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.102r
+Fluoxastrobin 609-207-6 361377-29-9 single chemical entity Component is a metabolite of the substance HEC5725-E-des-chlorophenyl (E)-5,6-dihydro-1,4,2-dioxazin-3-yl{2-[(5-fluoro-6-hydroxypyrimidin-4-yl)oxy]phenyl}methanone O-methyloxime Not in list C15H13FN4O5 Fc3c(O)ncnc3Oc2ccccc2C(=N\OC)/C=1OCCON=1 InChI=1/C15H13FN4O5/c1-22-19-12(15-20-24-7-6-23-15)9-4-2-3-5-10(9)25-14-11(16)13(21)17-8-18-14/h2-5,8H,6-7H2,1H3,(H,17,18,21)/b19-12+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fluoxastrobin (Final addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.102r
+Fluoxastrobin 609-207-6 361377-29-9 single chemical entity Component is a metabolite of the substance HEC5725-E-des-chlorophenyl (E)-5,6-dihydro-1,4,2-dioxazin-3-yl{2-[(5-fluoro-6-hydroxypyrimidin-4-yl)oxy]phenyl}methanone O-methyloxime Not in list C15H13FN4O5 Fc3c(O)ncnc3Oc2ccccc2C(=N\OC)/C=1OCCON=1 InChI=1/C15H13FN4O5/c1-22-19-12(15-20-24-7-6-23-15)9-4-2-3-5-10(9)25-14-11(16)13(21)17-8-18-14/h2-5,8H,6-7H2,1H3,(H,17,18,21)/b19-12+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluoxastrobin (Final addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.102r
+Fluoxastrobin 609-207-6 361377-29-9 single chemical entity Component is a metabolite of the substance HEC5725-E-des-chlorophenyl (E)-5,6-dihydro-1,4,2-dioxazin-3-yl{2-[(5-fluoro-6-hydroxypyrimidin-4-yl)oxy]phenyl}methanone O-methyloxime Not in list C15H13FN4O5 Fc3c(O)ncnc3Oc2ccccc2C(=N\OC)/C=1OCCON=1 InChI=1/C15H13FN4O5/c1-22-19-12(15-20-24-7-6-23-15)9-4-2-3-5-10(9)25-14-11(16)13(21)17-8-18-14/h2-5,8H,6-7H2,1H3,(H,17,18,21)/b19-12+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluoxastrobin (Final addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.102r
+Fluoxastrobin 609-207-6 361377-29-9 single chemical entity Component is a metabolite of the substance HEC5725-E-des-chlorophenyl (E)-5,6-dihydro-1,4,2-dioxazin-3-yl{2-[(5-fluoro-6-hydroxypyrimidin-4-yl)oxy]phenyl}methanone O-methyloxime Not in list C15H13FN4O5 Fc3c(O)ncnc3Oc2ccccc2C(=N\OC)/C=1OCCON=1 InChI=1/C15H13FN4O5/c1-22-19-12(15-20-24-7-6-23-15)9-4-2-3-5-10(9)25-14-11(16)13(21)17-8-18-14/h2-5,8H,6-7H2,1H3,(H,17,18,21)/b19-12+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fluoxastrobin (Final addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.102r
+Fluoxastrobin 609-207-6 361377-29-9 single chemical entity Component is a metabolite of the substance HEC5725-E-des-chlorophenyl (E)-5,6-dihydro-1,4,2-dioxazin-3-yl{2-[(5-fluoro-6-hydroxypyrimidin-4-yl)oxy]phenyl}methanone O-methyloxime Not in list C15H13FN4O5 Fc3c(O)ncnc3Oc2ccccc2C(=N\OC)/C=1OCCON=1 InChI=1/C15H13FN4O5/c1-22-19-12(15-20-24-7-6-23-15)9-4-2-3-5-10(9)25-14-11(16)13(21)17-8-18-14/h2-5,8H,6-7H2,1H3,(H,17,18,21)/b19-12+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fluoxastrobin (Final addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.102r
+Fluoxastrobin 609-207-6 361377-29-9 single chemical entity Component is a metabolite of the substance HEC5725-E-des-chlorophenyl (E)-5,6-dihydro-1,4,2-dioxazin-3-yl{2-[(5-fluoro-6-hydroxypyrimidin-4-yl)oxy]phenyl}methanone O-methyloxime Not in list C15H13FN4O5 Fc3c(O)ncnc3Oc2ccccc2C(=N\OC)/C=1OCCON=1 InChI=1/C15H13FN4O5/c1-22-19-12(15-20-24-7-6-23-15)9-4-2-3-5-10(9)25-14-11(16)13(21)17-8-18-14/h2-5,8H,6-7H2,1H3,(H,17,18,21)/b19-12+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fluoxastrobin (Final addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.102r
+Fluoxastrobin 609-207-6 361377-29-9 single chemical entity Component is a metabolite of the substance HEC5725-E-des-chlorophenyl (E)-5,6-dihydro-1,4,2-dioxazin-3-yl{2-[(5-fluoro-6-hydroxypyrimidin-4-yl)oxy]phenyl}methanone O-methyloxime Not in list C15H13FN4O5 Fc3c(O)ncnc3Oc2ccccc2C(=N\OC)/C=1OCCON=1 InChI=1/C15H13FN4O5/c1-22-19-12(15-20-24-7-6-23-15)9-4-2-3-5-10(9)25-14-11(16)13(21)17-8-18-14/h2-5,8H,6-7H2,1H3,(H,17,18,21)/b19-12+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fluoxastrobin (Final addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.102r
+Fluoxastrobin 609-207-6 361377-29-9 single chemical entity Component is a metabolite of the substance HEC5725-E-des-chlorophenyl (E)-5,6-dihydro-1,4,2-dioxazin-3-yl{2-[(5-fluoro-6-hydroxypyrimidin-4-yl)oxy]phenyl}methanone O-methyloxime Not in list C15H13FN4O5 Fc3c(O)ncnc3Oc2ccccc2C(=N\OC)/C=1OCCON=1 InChI=1/C15H13FN4O5/c1-22-19-12(15-20-24-7-6-23-15)9-4-2-3-5-10(9)25-14-11(16)13(21)17-8-18-14/h2-5,8H,6-7H2,1H3,(H,17,18,21)/b19-12+ organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fluoxastrobin (Final addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin 31Aug2005 2005 doi:10.2903/j.efsa.2005.102r
+Fenpropidin 67306-00-7 single chemical entity Component is identical to the substance Fenpropidin 67306-00-7 1-[3-(4-Tert-butylphenyl)-2-methylpropyl]piperidine Fenpropidin (sum of fenpropidin and its salts, expressed as fenpropidin) C19H31N CC(CC1=CC=C(C=C1)C(C)(C)C)CN2CCCCC2 InChI=1S/C19H31N/c1-16(15-20-12-6-5-7-13-20)14-17-8-10-18(11-9-17)19(2,3)4/h8-11,16H,5-7,12-15H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Sweden Fenpropidin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropidin 30Jan2008 2008 doi:10.2903/j.efsa.2008.124r
+Fenpropidin 67306-00-7 single chemical entity Component is identical to the substance Fenpropidin 67306-00-7 1-[3-(4-Tert-butylphenyl)-2-methylpropyl]piperidine Fenpropidin (sum of fenpropidin and its salts, expressed as fenpropidin) C19H31N CC(CC1=CC=C(C=C1)C(C)(C)C)CN2CCCCC2 InChI=1S/C19H31N/c1-16(15-20-12-6-5-7-13-20)14-17-8-10-18(11-9-17)19(2,3)4/h8-11,16H,5-7,12-15H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Sweden Fenpropidin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropidin 30Jan2008 2008 doi:10.2903/j.efsa.2008.124r
+Fenpropidin 67306-00-7 single chemical entity Component is identical to the substance Fenpropidin 67306-00-7 1-[3-(4-Tert-butylphenyl)-2-methylpropyl]piperidine Fenpropidin (sum of fenpropidin and its salts, expressed as fenpropidin) C19H31N CC(CC1=CC=C(C=C1)C(C)(C)C)CN2CCCCC2 InChI=1S/C19H31N/c1-16(15-20-12-6-5-7-13-20)14-17-8-10-18(11-9-17)19(2,3)4/h8-11,16H,5-7,12-15H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Sweden Fenpropidin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropidin 30Jan2008 2008 doi:10.2903/j.efsa.2008.124r
+Fenpropidin 67306-00-7 single chemical entity Component is identical to the substance Fenpropidin 67306-00-7 1-[3-(4-Tert-butylphenyl)-2-methylpropyl]piperidine Fenpropidin (sum of fenpropidin and its salts, expressed as fenpropidin) C19H31N CC(CC1=CC=C(C=C1)C(C)(C)C)CN2CCCCC2 InChI=1S/C19H31N/c1-16(15-20-12-6-5-7-13-20)14-17-8-10-18(11-9-17)19(2,3)4/h8-11,16H,5-7,12-15H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Sweden Fenpropidin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropidin 30Jan2008 2008 doi:10.2903/j.efsa.2008.124r
+Fenpropidin 67306-00-7 single chemical entity Component is identical to the substance Fenpropidin 67306-00-7 1-[3-(4-Tert-butylphenyl)-2-methylpropyl]piperidine Fenpropidin (sum of fenpropidin and its salts, expressed as fenpropidin) C19H31N CC(CC1=CC=C(C=C1)C(C)(C)C)CN2CCCCC2 InChI=1S/C19H31N/c1-16(15-20-12-6-5-7-13-20)14-17-8-10-18(11-9-17)19(2,3)4/h8-11,16H,5-7,12-15H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Sweden Fenpropidin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropidin 30Jan2008 2008 doi:10.2903/j.efsa.2008.124r
+Fenpropidin 67306-00-7 single chemical entity Component is identical to the substance Fenpropidin 67306-00-7 1-[3-(4-Tert-butylphenyl)-2-methylpropyl]piperidine Fenpropidin (sum of fenpropidin and its salts, expressed as fenpropidin) C19H31N CC(CC1=CC=C(C=C1)C(C)(C)C)CN2CCCCC2 InChI=1S/C19H31N/c1-16(15-20-12-6-5-7-13-20)14-17-8-10-18(11-9-17)19(2,3)4/h8-11,16H,5-7,12-15H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Sweden Fenpropidin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropidin 30Jan2008 2008 doi:10.2903/j.efsa.2008.124r
+Fenpropidin 67306-00-7 single chemical entity Component is identical to the substance Fenpropidin 67306-00-7 1-[3-(4-Tert-butylphenyl)-2-methylpropyl]piperidine Fenpropidin (sum of fenpropidin and its salts, expressed as fenpropidin) C19H31N CC(CC1=CC=C(C=C1)C(C)(C)C)CN2CCCCC2 InChI=1S/C19H31N/c1-16(15-20-12-6-5-7-13-20)14-17-8-10-18(11-9-17)19(2,3)4/h8-11,16H,5-7,12-15H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Sweden Fenpropidin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropidin 30Jan2008 2008 doi:10.2903/j.efsa.2008.124r
+Fenpropidin 67306-00-7 single chemical entity Component is identical to the substance Fenpropidin 67306-00-7 1-[3-(4-Tert-butylphenyl)-2-methylpropyl]piperidine Fenpropidin (sum of fenpropidin and its salts, expressed as fenpropidin) C19H31N CC(CC1=CC=C(C=C1)C(C)(C)C)CN2CCCCC2 InChI=1S/C19H31N/c1-16(15-20-12-6-5-7-13-20)14-17-8-10-18(11-9-17)19(2,3)4/h8-11,16H,5-7,12-15H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Sweden Fenpropidin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropidin 30Jan2008 2008 doi:10.2903/j.efsa.2008.124r
+Fenpropidin 67306-00-7 single chemical entity Component is identical to the substance Fenpropidin 67306-00-7 1-[3-(4-Tert-butylphenyl)-2-methylpropyl]piperidine Fenpropidin (sum of fenpropidin and its salts, expressed as fenpropidin) C19H31N CC(CC1=CC=C(C=C1)C(C)(C)C)CN2CCCCC2 InChI=1S/C19H31N/c1-16(15-20-12-6-5-7-13-20)14-17-8-10-18(11-9-17)19(2,3)4/h8-11,16H,5-7,12-15H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Sweden Fenpropidin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropidin 30Jan2008 2008 doi:10.2903/j.efsa.2008.124r
+Fenpropidin 67306-00-7 single chemical entity Component is identical to the substance Fenpropidin 67306-00-7 1-[3-(4-Tert-butylphenyl)-2-methylpropyl]piperidine Fenpropidin (sum of fenpropidin and its salts, expressed as fenpropidin) C19H31N CC(CC1=CC=C(C=C1)C(C)(C)C)CN2CCCCC2 InChI=1S/C19H31N/c1-16(15-20-12-6-5-7-13-20)14-17-8-10-18(11-9-17)19(2,3)4/h8-11,16H,5-7,12-15H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Sweden Fenpropidin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropidin 30Jan2008 2008 doi:10.2903/j.efsa.2008.124r
+Fenpropidin 67306-00-7 single chemical entity Component is identical to the substance Fenpropidin 67306-00-7 1-[3-(4-Tert-butylphenyl)-2-methylpropyl]piperidine Fenpropidin (sum of fenpropidin and its salts, expressed as fenpropidin) C19H31N CC(CC1=CC=C(C=C1)C(C)(C)C)CN2CCCCC2 InChI=1S/C19H31N/c1-16(15-20-12-6-5-7-13-20)14-17-8-10-18(11-9-17)19(2,3)4/h8-11,16H,5-7,12-15H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Sweden Fenpropidin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropidin 30Jan2008 2008 doi:10.2903/j.efsa.2008.124r
+Fenpropidin 67306-00-7 single chemical entity Component is identical to the substance Fenpropidin 67306-00-7 1-[3-(4-Tert-butylphenyl)-2-methylpropyl]piperidine Fenpropidin (sum of fenpropidin and its salts, expressed as fenpropidin) C19H31N CC(CC1=CC=C(C=C1)C(C)(C)C)CN2CCCCC2 InChI=1S/C19H31N/c1-16(15-20-12-6-5-7-13-20)14-17-8-10-18(11-9-17)19(2,3)4/h8-11,16H,5-7,12-15H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Sweden Fenpropidin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropidin 30Jan2008 2008 doi:10.2903/j.efsa.2008.124r
+Fenpropidin 67306-00-7 single chemical entity Component is identical to the substance Fenpropidin 67306-00-7 1-[3-(4-Tert-butylphenyl)-2-methylpropyl]piperidine Fenpropidin (sum of fenpropidin and its salts, expressed as fenpropidin) C19H31N CC(CC1=CC=C(C=C1)C(C)(C)C)CN2CCCCC2 InChI=1S/C19H31N/c1-16(15-20-12-6-5-7-13-20)14-17-8-10-18(11-9-17)19(2,3)4/h8-11,16H,5-7,12-15H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: Sweden Fenpropidin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropidin 30Jan2008 2008 doi:10.2903/j.efsa.2008.124r
+Fenpropidin 67306-00-7 single chemical entity Component is identical to the substance Fenpropidin 67306-00-7 1-[3-(4-Tert-butylphenyl)-2-methylpropyl]piperidine Fenpropidin (sum of fenpropidin and its salts, expressed as fenpropidin) C19H31N CC(CC1=CC=C(C=C1)C(C)(C)C)CN2CCCCC2 InChI=1S/C19H31N/c1-16(15-20-12-6-5-7-13-20)14-17-8-10-18(11-9-17)19(2,3)4/h8-11,16H,5-7,12-15H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: Sweden Fenpropidin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropidin 30Jan2008 2008 doi:10.2903/j.efsa.2008.124r
+Fenpropidin 67306-00-7 single chemical entity Component is identical to the substance Fenpropidin 67306-00-7 1-[3-(4-Tert-butylphenyl)-2-methylpropyl]piperidine Fenpropidin (sum of fenpropidin and its salts, expressed as fenpropidin) C19H31N CC(CC1=CC=C(C=C1)C(C)(C)C)CN2CCCCC2 InChI=1S/C19H31N/c1-16(15-20-12-6-5-7-13-20)14-17-8-10-18(11-9-17)19(2,3)4/h8-11,16H,5-7,12-15H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Sweden Fenpropidin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropidin 30Jan2008 2008 doi:10.2903/j.efsa.2008.124r
+Fenpropidin 67306-00-7 single chemical entity Component is identical to the substance Fenpropidin 67306-00-7 1-[3-(4-Tert-butylphenyl)-2-methylpropyl]piperidine Fenpropidin (sum of fenpropidin and its salts, expressed as fenpropidin) C19H31N CC(CC1=CC=C(C=C1)C(C)(C)C)CN2CCCCC2 InChI=1S/C19H31N/c1-16(15-20-12-6-5-7-13-20)14-17-8-10-18(11-9-17)19(2,3)4/h8-11,16H,5-7,12-15H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Tif:MAGf(SPF) 10 Male/Female oral: gavage 24.0000000000 h yes not applicable Negative no evidence RMS: Sweden Fenpropidin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropidin 30Jan2008 2008 doi:10.2903/j.efsa.2008.124r
+Fenpropidin 67306-00-7 single chemical entity Component is identical to the substance Fenpropidin 67306-00-7 1-[3-(4-Tert-butylphenyl)-2-methylpropyl]piperidine Fenpropidin (sum of fenpropidin and its salts, expressed as fenpropidin) C19H31N CC(CC1=CC=C(C=C1)C(C)(C)C)CN2CCCCC2 InChI=1S/C19H31N/c1-16(15-20-12-6-5-7-13-20)14-17-8-10-18(11-9-17)19(2,3)4/h8-11,16H,5-7,12-15H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Tif:MAGf(SPF) 10 Male/Female oral: gavage 48.0000000000 h yes not applicable Negative no evidence RMS: Sweden Fenpropidin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropidin 30Jan2008 2008 doi:10.2903/j.efsa.2008.124r
+Fenpropidin 67306-00-7 single chemical entity Component is identical to the substance Fenpropidin 67306-00-7 1-[3-(4-Tert-butylphenyl)-2-methylpropyl]piperidine Fenpropidin (sum of fenpropidin and its salts, expressed as fenpropidin) C19H31N CC(CC1=CC=C(C=C1)C(C)(C)C)CN2CCCCC2 InChI=1S/C19H31N/c1-16(15-20-12-6-5-7-13-20)14-17-8-10-18(11-9-17)19(2,3)4/h8-11,16H,5-7,12-15H2,1-4H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Tif:MAGf(SPF) 10 Male/Female oral: gavage 16.0000000000 h yes not applicable Negative no evidence RMS: Sweden Fenpropidin 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropidin 30Jan2008 2008 doi:10.2903/j.efsa.2008.124r
+Fenpropidin 67306-00-7 single chemical entity Component is a metabolite of the substance 1-[3-(4-tert-butyl-phenyl)-2-methyl-propyl]-piperidine-1-oxide 1-[3-(4-tert-butyl-phenyl)-2-methyl-propyl]-piperidine-1-oxide Not in list C19H31NO [O-][N+]2(CC(C)Cc1ccc(cc1)C(C)(C)C)CCCCC2 InChI=1/C19H31NO/c1-16(15-20(21)12-6-5-7-13-20)14-17-8-10-18(11-9-17)19(2,3)4/h8-11,16H,5-7,12-15H2,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Sweden Fenpropidin (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropidin 30Jan2008 2008 doi:10.2903/j.efsa.2008.124r
+Fenpropidin 67306-00-7 single chemical entity Component is a metabolite of the substance 1-[3-(4-tert-butyl-phenyl)-2-methyl-propyl]-piperidine-1-oxide 1-[3-(4-tert-butyl-phenyl)-2-methyl-propyl]-piperidine-1-oxide Not in list C19H31NO [O-][N+]2(CC(C)Cc1ccc(cc1)C(C)(C)C)CCCCC2 InChI=1/C19H31NO/c1-16(15-20(21)12-6-5-7-13-20)14-17-8-10-18(11-9-17)19(2,3)4/h8-11,16H,5-7,12-15H2,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Sweden Fenpropidin (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropidin 30Jan2008 2008 doi:10.2903/j.efsa.2008.124r
+Fenpropidin 67306-00-7 single chemical entity Component is a metabolite of the substance 1-[3-(4-tert-butyl-phenyl)-2-methyl-propyl]-piperidine-1-oxide 1-[3-(4-tert-butyl-phenyl)-2-methyl-propyl]-piperidine-1-oxide Not in list C19H31NO [O-][N+]2(CC(C)Cc1ccc(cc1)C(C)(C)C)CCCCC2 InChI=1/C19H31NO/c1-16(15-20(21)12-6-5-7-13-20)14-17-8-10-18(11-9-17)19(2,3)4/h8-11,16H,5-7,12-15H2,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Sweden Fenpropidin (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropidin 30Jan2008 2008 doi:10.2903/j.efsa.2008.124r
+Fenpropidin 67306-00-7 single chemical entity Component is a metabolite of the substance 1-[3-(4-tert-butyl-phenyl)-2-methyl-propyl]-piperidine-1-oxide 1-[3-(4-tert-butyl-phenyl)-2-methyl-propyl]-piperidine-1-oxide Not in list C19H31NO [O-][N+]2(CC(C)Cc1ccc(cc1)C(C)(C)C)CCCCC2 InChI=1/C19H31NO/c1-16(15-20(21)12-6-5-7-13-20)14-17-8-10-18(11-9-17)19(2,3)4/h8-11,16H,5-7,12-15H2,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Sweden Fenpropidin (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropidin 30Jan2008 2008 doi:10.2903/j.efsa.2008.124r
+Fenpropidin 67306-00-7 single chemical entity Component is a metabolite of the substance 1-[3-(4-tert-butyl-phenyl)-2-methyl-propyl]-piperidine-1-oxide 1-[3-(4-tert-butyl-phenyl)-2-methyl-propyl]-piperidine-1-oxide Not in list C19H31NO [O-][N+]2(CC(C)Cc1ccc(cc1)C(C)(C)C)CCCCC2 InChI=1/C19H31NO/c1-16(15-20(21)12-6-5-7-13-20)14-17-8-10-18(11-9-17)19(2,3)4/h8-11,16H,5-7,12-15H2,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Sweden Fenpropidin (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropidin 30Jan2008 2008 doi:10.2903/j.efsa.2008.124r
+Fenpropidin 67306-00-7 single chemical entity Component is a metabolite of the substance 1-[3-(4-tert-butyl-phenyl)-2-methyl-propyl]-piperidine-1-oxide 1-[3-(4-tert-butyl-phenyl)-2-methyl-propyl]-piperidine-1-oxide Not in list C19H31NO [O-][N+]2(CC(C)Cc1ccc(cc1)C(C)(C)C)CCCCC2 InChI=1/C19H31NO/c1-16(15-20(21)12-6-5-7-13-20)14-17-8-10-18(11-9-17)19(2,3)4/h8-11,16H,5-7,12-15H2,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Sweden Fenpropidin (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropidin 30Jan2008 2008 doi:10.2903/j.efsa.2008.124r
+Fenpropidin 67306-00-7 single chemical entity Component is a metabolite of the substance 1-[3-(4-tert-butyl-phenyl)-2-methyl-propyl]-piperidine-1-oxide 1-[3-(4-tert-butyl-phenyl)-2-methyl-propyl]-piperidine-1-oxide Not in list C19H31NO [O-][N+]2(CC(C)Cc1ccc(cc1)C(C)(C)C)CCCCC2 InChI=1/C19H31NO/c1-16(15-20(21)12-6-5-7-13-20)14-17-8-10-18(11-9-17)19(2,3)4/h8-11,16H,5-7,12-15H2,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Sweden Fenpropidin (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropidin 30Jan2008 2008 doi:10.2903/j.efsa.2008.124r
+Fenpropidin 67306-00-7 single chemical entity Component is a metabolite of the substance 1-[3-(4-tert-butyl-phenyl)-2-methyl-propyl]-piperidine-1-oxide 1-[3-(4-tert-butyl-phenyl)-2-methyl-propyl]-piperidine-1-oxide Not in list C19H31NO [O-][N+]2(CC(C)Cc1ccc(cc1)C(C)(C)C)CCCCC2 InChI=1/C19H31NO/c1-16(15-20(21)12-6-5-7-13-20)14-17-8-10-18(11-9-17)19(2,3)4/h8-11,16H,5-7,12-15H2,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Sweden Fenpropidin (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropidin 30Jan2008 2008 doi:10.2903/j.efsa.2008.124r
+Fenpropidin 67306-00-7 single chemical entity Component is a metabolite of the substance 1-[3-(4-tert-butyl-phenyl)-2-methyl-propyl]-piperidine-1-oxide 1-[3-(4-tert-butyl-phenyl)-2-methyl-propyl]-piperidine-1-oxide Not in list C19H31NO [O-][N+]2(CC(C)Cc1ccc(cc1)C(C)(C)C)CCCCC2 InChI=1/C19H31NO/c1-16(15-20(21)12-6-5-7-13-20)14-17-8-10-18(11-9-17)19(2,3)4/h8-11,16H,5-7,12-15H2,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Sweden Fenpropidin (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropidin 30Jan2008 2008 doi:10.2903/j.efsa.2008.124r
+Fenpropidin 67306-00-7 single chemical entity Component is a metabolite of the substance 1-[3-(4-tert-butyl-phenyl)-2-methyl-propyl]-piperidine-1-oxide 1-[3-(4-tert-butyl-phenyl)-2-methyl-propyl]-piperidine-1-oxide Not in list C19H31NO [O-][N+]2(CC(C)Cc1ccc(cc1)C(C)(C)C)CCCCC2 InChI=1/C19H31NO/c1-16(15-20(21)12-6-5-7-13-20)14-17-8-10-18(11-9-17)19(2,3)4/h8-11,16H,5-7,12-15H2,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Sweden Fenpropidin (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropidin 30Jan2008 2008 doi:10.2903/j.efsa.2008.124r
+Fenpropidin 67306-00-7 single chemical entity Component is a metabolite of the substance 1-[3-(4-tert-butyl-phenyl)-2-methyl-propyl]-piperidine-1-oxide 1-[3-(4-tert-butyl-phenyl)-2-methyl-propyl]-piperidine-1-oxide Not in list C19H31NO [O-][N+]2(CC(C)Cc1ccc(cc1)C(C)(C)C)CCCCC2 InChI=1/C19H31NO/c1-16(15-20(21)12-6-5-7-13-20)14-17-8-10-18(11-9-17)19(2,3)4/h8-11,16H,5-7,12-15H2,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Sweden Fenpropidin (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropidin 30Jan2008 2008 doi:10.2903/j.efsa.2008.124r
+Fenpropidin 67306-00-7 single chemical entity Component is a metabolite of the substance 1-[3-(4-tert-butyl-phenyl)-2-methyl-propyl]-piperidine-1-oxide 1-[3-(4-tert-butyl-phenyl)-2-methyl-propyl]-piperidine-1-oxide Not in list C19H31NO [O-][N+]2(CC(C)Cc1ccc(cc1)C(C)(C)C)CCCCC2 InChI=1/C19H31NO/c1-16(15-20(21)12-6-5-7-13-20)14-17-8-10-18(11-9-17)19(2,3)4/h8-11,16H,5-7,12-15H2,1-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Sweden Fenpropidin (Addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropidin 30Jan2008 2008 doi:10.2903/j.efsa.2008.124r
+Fluquinconazole 411-960-9 136426-54-5 single chemical entity Component is identical to the substance Fluquinconazole 411-960-9 136426-54-5 3-(2,4-dichlorophenyl)-6-fluoro-2-(1H-1,2,4-triazol-1-yl)quinazolin-4(3H)-one Fluquinconazole C16H8Cl2FN5O Clc4ccc(N1C(=O)c3cc(F)ccc3N=C1n2cncn2)c(Cl)c4 InChI=1S/C16H8Cl2FN5O/c17-9-1-4-14(12(18)5-9)24-15(25)11-6-10(19)2-3-13(11)22-16(24)23-8-20-7-21-23/h1-8H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Ireland Fluquinconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole 11May2011 2011 doi:10.2903/j.efsa.2011.2096
+Fluquinconazole 411-960-9 136426-54-5 single chemical entity Component is identical to the substance Fluquinconazole 411-960-9 136426-54-5 3-(2,4-dichlorophenyl)-6-fluoro-2-(1H-1,2,4-triazol-1-yl)quinazolin-4(3H)-one Fluquinconazole C16H8Cl2FN5O Clc4ccc(N1C(=O)c3cc(F)ccc3N=C1n2cncn2)c(Cl)c4 InChI=1S/C16H8Cl2FN5O/c17-9-1-4-14(12(18)5-9)24-15(25)11-6-10(19)2-3-13(11)22-16(24)23-8-20-7-21-23/h1-8H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Ireland Fluquinconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole 11May2011 2011 doi:10.2903/j.efsa.2011.2096
+Fluquinconazole 411-960-9 136426-54-5 single chemical entity Component is identical to the substance Fluquinconazole 411-960-9 136426-54-5 3-(2,4-dichlorophenyl)-6-fluoro-2-(1H-1,2,4-triazol-1-yl)quinazolin-4(3H)-one Fluquinconazole C16H8Cl2FN5O Clc4ccc(N1C(=O)c3cc(F)ccc3N=C1n2cncn2)c(Cl)c4 InChI=1S/C16H8Cl2FN5O/c17-9-1-4-14(12(18)5-9)24-15(25)11-6-10(19)2-3-13(11)22-16(24)23-8-20-7-21-23/h1-8H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Ireland Fluquinconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole 11May2011 2011 doi:10.2903/j.efsa.2011.2096
+Fluquinconazole 411-960-9 136426-54-5 single chemical entity Component is identical to the substance Fluquinconazole 411-960-9 136426-54-5 3-(2,4-dichlorophenyl)-6-fluoro-2-(1H-1,2,4-triazol-1-yl)quinazolin-4(3H)-one Fluquinconazole C16H8Cl2FN5O Clc4ccc(N1C(=O)c3cc(F)ccc3N=C1n2cncn2)c(Cl)c4 InChI=1S/C16H8Cl2FN5O/c17-9-1-4-14(12(18)5-9)24-15(25)11-6-10(19)2-3-13(11)22-16(24)23-8-20-7-21-23/h1-8H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Ireland Fluquinconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole 11May2011 2011 doi:10.2903/j.efsa.2011.2096
+Fluquinconazole 411-960-9 136426-54-5 single chemical entity Component is identical to the substance Fluquinconazole 411-960-9 136426-54-5 3-(2,4-dichlorophenyl)-6-fluoro-2-(1H-1,2,4-triazol-1-yl)quinazolin-4(3H)-one Fluquinconazole C16H8Cl2FN5O Clc4ccc(N1C(=O)c3cc(F)ccc3N=C1n2cncn2)c(Cl)c4 InChI=1S/C16H8Cl2FN5O/c17-9-1-4-14(12(18)5-9)24-15(25)11-6-10(19)2-3-13(11)22-16(24)23-8-20-7-21-23/h1-8H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Ireland Fluquinconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole 11May2011 2011 doi:10.2903/j.efsa.2011.2096
+Fluquinconazole 411-960-9 136426-54-5 single chemical entity Component is identical to the substance Fluquinconazole 411-960-9 136426-54-5 3-(2,4-dichlorophenyl)-6-fluoro-2-(1H-1,2,4-triazol-1-yl)quinazolin-4(3H)-one Fluquinconazole C16H8Cl2FN5O Clc4ccc(N1C(=O)c3cc(F)ccc3N=C1n2cncn2)c(Cl)c4 InChI=1S/C16H8Cl2FN5O/c17-9-1-4-14(12(18)5-9)24-15(25)11-6-10(19)2-3-13(11)22-16(24)23-8-20-7-21-23/h1-8H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Ireland Fluquinconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole 11May2011 2011 doi:10.2903/j.efsa.2011.2096
+Fluquinconazole 411-960-9 136426-54-5 single chemical entity Component is identical to the substance Fluquinconazole 411-960-9 136426-54-5 3-(2,4-dichlorophenyl)-6-fluoro-2-(1H-1,2,4-triazol-1-yl)quinazolin-4(3H)-one Fluquinconazole C16H8Cl2FN5O Clc4ccc(N1C(=O)c3cc(F)ccc3N=C1n2cncn2)c(Cl)c4 InChI=1S/C16H8Cl2FN5O/c17-9-1-4-14(12(18)5-9)24-15(25)11-6-10(19)2-3-13(11)22-16(24)23-8-20-7-21-23/h1-8H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Ireland Fluquinconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole 11May2011 2011 doi:10.2903/j.efsa.2011.2096
+Fluquinconazole 411-960-9 136426-54-5 single chemical entity Component is identical to the substance Fluquinconazole 411-960-9 136426-54-5 3-(2,4-dichlorophenyl)-6-fluoro-2-(1H-1,2,4-triazol-1-yl)quinazolin-4(3H)-one Fluquinconazole C16H8Cl2FN5O Clc4ccc(N1C(=O)c3cc(F)ccc3N=C1n2cncn2)c(Cl)c4 InChI=1S/C16H8Cl2FN5O/c17-9-1-4-14(12(18)5-9)24-15(25)11-6-10(19)2-3-13(11)22-16(24)23-8-20-7-21-23/h1-8H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Ireland Fluquinconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole 11May2011 2011 doi:10.2903/j.efsa.2011.2096
+Fluquinconazole 411-960-9 136426-54-5 single chemical entity Component is identical to the substance Fluquinconazole 411-960-9 136426-54-5 3-(2,4-dichlorophenyl)-6-fluoro-2-(1H-1,2,4-triazol-1-yl)quinazolin-4(3H)-one Fluquinconazole C16H8Cl2FN5O Clc4ccc(N1C(=O)c3cc(F)ccc3N=C1n2cncn2)c(Cl)c4 InChI=1S/C16H8Cl2FN5O/c17-9-1-4-14(12(18)5-9)24-15(25)11-6-10(19)2-3-13(11)22-16(24)23-8-20-7-21-23/h1-8H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Ireland Fluquinconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole 11May2011 2011 doi:10.2903/j.efsa.2011.2096
+Fluquinconazole 411-960-9 136426-54-5 single chemical entity Component is identical to the substance Fluquinconazole 411-960-9 136426-54-5 3-(2,4-dichlorophenyl)-6-fluoro-2-(1H-1,2,4-triazol-1-yl)quinazolin-4(3H)-one Fluquinconazole C16H8Cl2FN5O Clc4ccc(N1C(=O)c3cc(F)ccc3N=C1n2cncn2)c(Cl)c4 InChI=1S/C16H8Cl2FN5O/c17-9-1-4-14(12(18)5-9)24-15(25)11-6-10(19)2-3-13(11)22-16(24)23-8-20-7-21-23/h1-8H organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Ireland Fluquinconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole 11May2011 2011 doi:10.2903/j.efsa.2011.2096
+Fluquinconazole 411-960-9 136426-54-5 single chemical entity Component is identical to the substance Fluquinconazole 411-960-9 136426-54-5 3-(2,4-dichlorophenyl)-6-fluoro-2-(1H-1,2,4-triazol-1-yl)quinazolin-4(3H)-one Fluquinconazole C16H8Cl2FN5O Clc4ccc(N1C(=O)c3cc(F)ccc3N=C1n2cncn2)c(Cl)c4 InChI=1S/C16H8Cl2FN5O/c17-9-1-4-14(12(18)5-9)24-15(25)11-6-10(19)2-3-13(11)22-16(24)23-8-20-7-21-23/h1-8H organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Ireland Fluquinconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole 11May2011 2011 doi:10.2903/j.efsa.2011.2096
+Fluquinconazole 411-960-9 136426-54-5 single chemical entity Component is identical to the substance Fluquinconazole 411-960-9 136426-54-5 3-(2,4-dichlorophenyl)-6-fluoro-2-(1H-1,2,4-triazol-1-yl)quinazolin-4(3H)-one Fluquinconazole C16H8Cl2FN5O Clc4ccc(N1C(=O)c3cc(F)ccc3N=C1n2cncn2)c(Cl)c4 InChI=1S/C16H8Cl2FN5O/c17-9-1-4-14(12(18)5-9)24-15(25)11-6-10(19)2-3-13(11)22-16(24)23-8-20-7-21-23/h1-8H organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Ireland Fluquinconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole 11May2011 2011 doi:10.2903/j.efsa.2011.2096
+Fluquinconazole 411-960-9 136426-54-5 single chemical entity Component is identical to the substance Fluquinconazole 411-960-9 136426-54-5 3-(2,4-dichlorophenyl)-6-fluoro-2-(1H-1,2,4-triazol-1-yl)quinazolin-4(3H)-one Fluquinconazole C16H8Cl2FN5O Clc4ccc(N1C(=O)c3cc(F)ccc3N=C1n2cncn2)c(Cl)c4 InChI=1S/C16H8Cl2FN5O/c17-9-1-4-14(12(18)5-9)24-15(25)11-6-10(19)2-3-13(11)22-16(24)23-8-20-7-21-23/h1-8H organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Ireland Fluquinconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole 11May2011 2011 doi:10.2903/j.efsa.2011.2096
+Fluquinconazole 411-960-9 136426-54-5 single chemical entity Component is identical to the substance Fluquinconazole 411-960-9 136426-54-5 3-(2,4-dichlorophenyl)-6-fluoro-2-(1H-1,2,4-triazol-1-yl)quinazolin-4(3H)-one Fluquinconazole C16H8Cl2FN5O Clc4ccc(N1C(=O)c3cc(F)ccc3N=C1n2cncn2)c(Cl)c4 InChI=1S/C16H8Cl2FN5O/c17-9-1-4-14(12(18)5-9)24-15(25)11-6-10(19)2-3-13(11)22-16(24)23-8-20-7-21-23/h1-8H organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Ireland Fluquinconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole 11May2011 2011 doi:10.2903/j.efsa.2011.2096
+Fluquinconazole 411-960-9 136426-54-5 single chemical entity Component is identical to the substance Fluquinconazole 411-960-9 136426-54-5 3-(2,4-dichlorophenyl)-6-fluoro-2-(1H-1,2,4-triazol-1-yl)quinazolin-4(3H)-one Fluquinconazole C16H8Cl2FN5O Clc4ccc(N1C(=O)c3cc(F)ccc3N=C1n2cncn2)c(Cl)c4 InChI=1S/C16H8Cl2FN5O/c17-9-1-4-14(12(18)5-9)24-15(25)11-6-10(19)2-3-13(11)22-16(24)23-8-20-7-21-23/h1-8H organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Ireland Fluquinconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole 11May2011 2011 doi:10.2903/j.efsa.2011.2096
+Fluquinconazole 411-960-9 136426-54-5 single chemical entity Component is identical to the substance Fluquinconazole 411-960-9 136426-54-5 3-(2,4-dichlorophenyl)-6-fluoro-2-(1H-1,2,4-triazol-1-yl)quinazolin-4(3H)-one Fluquinconazole C16H8Cl2FN5O Clc4ccc(N1C(=O)c3cc(F)ccc3N=C1n2cncn2)c(Cl)c4 InChI=1S/C16H8Cl2FN5O/c17-9-1-4-14(12(18)5-9)24-15(25)11-6-10(19)2-3-13(11)22-16(24)23-8-20-7-21-23/h1-8H organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Ireland Fluquinconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole 11May2011 2011 doi:10.2903/j.efsa.2011.2096
+Fluquinconazole 411-960-9 136426-54-5 single chemical entity Component is identical to the substance Fluquinconazole 411-960-9 136426-54-5 3-(2,4-dichlorophenyl)-6-fluoro-2-(1H-1,2,4-triazol-1-yl)quinazolin-4(3H)-one Fluquinconazole C16H8Cl2FN5O Clc4ccc(N1C(=O)c3cc(F)ccc3N=C1n2cncn2)c(Cl)c4 InChI=1S/C16H8Cl2FN5O/c17-9-1-4-14(12(18)5-9)24-15(25)11-6-10(19)2-3-13(11)22-16(24)23-8-20-7-21-23/h1-8H organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 30 Male/Female oral: gavage 72.0000000000 h yes not applicable Negative no evidence RMS: Ireland Fluquinconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole 11May2011 2011 doi:10.2903/j.efsa.2011.2096
+Fluquinconazole 411-960-9 136426-54-5 single chemical entity Component is identical to the substance Fluquinconazole 411-960-9 136426-54-5 3-(2,4-dichlorophenyl)-6-fluoro-2-(1H-1,2,4-triazol-1-yl)quinazolin-4(3H)-one Fluquinconazole C16H8Cl2FN5O Clc4ccc(N1C(=O)c3cc(F)ccc3N=C1n2cncn2)c(Cl)c4 InChI=1S/C16H8Cl2FN5O/c17-9-1-4-14(12(18)5-9)24-15(25)11-6-10(19)2-3-13(11)22-16(24)23-8-20-7-21-23/h1-8H organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 30 Male/Female oral: gavage 48.0000000000 h yes not applicable Negative no evidence RMS: Ireland Fluquinconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole 11May2011 2011 doi:10.2903/j.efsa.2011.2096
+Fluquinconazole 411-960-9 136426-54-5 single chemical entity Component is identical to the substance Fluquinconazole 411-960-9 136426-54-5 3-(2,4-dichlorophenyl)-6-fluoro-2-(1H-1,2,4-triazol-1-yl)quinazolin-4(3H)-one Fluquinconazole C16H8Cl2FN5O Clc4ccc(N1C(=O)c3cc(F)ccc3N=C1n2cncn2)c(Cl)c4 InChI=1S/C16H8Cl2FN5O/c17-9-1-4-14(12(18)5-9)24-15(25)11-6-10(19)2-3-13(11)22-16(24)23-8-20-7-21-23/h1-8H organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 30 Male/Female oral: gavage 24.0000000000 h yes not applicable Negative no evidence RMS: Ireland Fluquinconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole 11May2011 2011 doi:10.2903/j.efsa.2011.2096
+Fluquinconazole 411-960-9 136426-54-5 single chemical entity Component is identical to the substance Fluquinconazole 411-960-9 136426-54-5 3-(2,4-dichlorophenyl)-6-fluoro-2-(1H-1,2,4-triazol-1-yl)quinazolin-4(3H)-one Fluquinconazole C16H8Cl2FN5O Clc4ccc(N1C(=O)c3cc(F)ccc3N=C1n2cncn2)c(Cl)c4 InChI=1S/C16H8Cl2FN5O/c17-9-1-4-14(12(18)5-9)24-15(25)11-6-10(19)2-3-13(11)22-16(24)23-8-20-7-21-23/h1-8H organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo Equivalent or similar to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) Yes Acceptable Rat (as animal) Crj:CD(SD) 3 Male oral: gavage 14.0000000000 h yes not applicable Negative RMS: Ireland Fluquinconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole 11May2011 2011 doi:10.2903/j.efsa.2011.2096
+Fluquinconazole 411-960-9 136426-54-5 single chemical entity Component is identical to the substance Fluquinconazole 411-960-9 136426-54-5 3-(2,4-dichlorophenyl)-6-fluoro-2-(1H-1,2,4-triazol-1-yl)quinazolin-4(3H)-one Fluquinconazole C16H8Cl2FN5O Clc4ccc(N1C(=O)c3cc(F)ccc3N=C1n2cncn2)c(Cl)c4 InChI=1S/C16H8Cl2FN5O/c17-9-1-4-14(12(18)5-9)24-15(25)11-6-10(19)2-3-13(11)22-16(24)23-8-20-7-21-23/h1-8H organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo Equivalent or similar to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) Yes Acceptable Rat (as animal) Crj:CD(SD) 3 Male oral: gavage 2.0000000000 h yes not applicable Negative RMS: Ireland Fluquinconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole 11May2011 2011 doi:10.2903/j.efsa.2011.2096
+Fluquinconazole 411-960-9 136426-54-5 single chemical entity Component is a metabolite of the substance 3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione 3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione Not in list C14H7Cl2FN2O2 Clc1ccc(c(Cl)c1)N2C(=O)c3cc(F)ccc3NC2=O InChI=1S/C14H7Cl2FN2O2/c15-7-1-4-12(10(16)5-7)19-13(20)9-6-8(17)2-3-11(9)18-14(19)21/h1-6H,(H,18,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Ireland Fluquinconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole 11May2011 2011 doi:10.2903/j.efsa.2011.2096
+Fluquinconazole 411-960-9 136426-54-5 single chemical entity Component is a metabolite of the substance 3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione 3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione Not in list C14H7Cl2FN2O2 Clc1ccc(c(Cl)c1)N2C(=O)c3cc(F)ccc3NC2=O InChI=1S/C14H7Cl2FN2O2/c15-7-1-4-12(10(16)5-7)19-13(20)9-6-8(17)2-3-11(9)18-14(19)21/h1-6H,(H,18,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Ireland Fluquinconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole 11May2011 2011 doi:10.2903/j.efsa.2011.2096
+Fluquinconazole 411-960-9 136426-54-5 single chemical entity Component is a metabolite of the substance 3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione 3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione Not in list C14H7Cl2FN2O2 Clc1ccc(c(Cl)c1)N2C(=O)c3cc(F)ccc3NC2=O InChI=1S/C14H7Cl2FN2O2/c15-7-1-4-12(10(16)5-7)19-13(20)9-6-8(17)2-3-11(9)18-14(19)21/h1-6H,(H,18,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Ireland Fluquinconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole 11May2011 2011 doi:10.2903/j.efsa.2011.2096
+Fluquinconazole 411-960-9 136426-54-5 single chemical entity Component is a metabolite of the substance 3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione 3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione Not in list C14H7Cl2FN2O2 Clc1ccc(c(Cl)c1)N2C(=O)c3cc(F)ccc3NC2=O InChI=1S/C14H7Cl2FN2O2/c15-7-1-4-12(10(16)5-7)19-13(20)9-6-8(17)2-3-11(9)18-14(19)21/h1-6H,(H,18,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: Ireland Fluquinconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole 11May2011 2011 doi:10.2903/j.efsa.2011.2096
+Fluquinconazole 411-960-9 136426-54-5 single chemical entity Component is a metabolite of the substance 3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione 3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione Not in list C14H7Cl2FN2O2 Clc1ccc(c(Cl)c1)N2C(=O)c3cc(F)ccc3NC2=O InChI=1S/C14H7Cl2FN2O2/c15-7-1-4-12(10(16)5-7)19-13(20)9-6-8(17)2-3-11(9)18-14(19)21/h1-6H,(H,18,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: Ireland Fluquinconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole 11May2011 2011 doi:10.2903/j.efsa.2011.2096
+Fluquinconazole 411-960-9 136426-54-5 single chemical entity Component is a metabolite of the substance 3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione 3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione Not in list C14H7Cl2FN2O2 Clc1ccc(c(Cl)c1)N2C(=O)c3cc(F)ccc3NC2=O InChI=1S/C14H7Cl2FN2O2/c15-7-1-4-12(10(16)5-7)19-13(20)9-6-8(17)2-3-11(9)18-14(19)21/h1-6H,(H,18,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Ireland Fluquinconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole 11May2011 2011 doi:10.2903/j.efsa.2011.2096
+Fluquinconazole 411-960-9 136426-54-5 single chemical entity Component is a metabolite of the substance 3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione 3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione Not in list C14H7Cl2FN2O2 Clc1ccc(c(Cl)c1)N2C(=O)c3cc(F)ccc3NC2=O InChI=1S/C14H7Cl2FN2O2/c15-7-1-4-12(10(16)5-7)19-13(20)9-6-8(17)2-3-11(9)18-14(19)21/h1-6H,(H,18,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Ireland Fluquinconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole 11May2011 2011 doi:10.2903/j.efsa.2011.2096
+Fluquinconazole 411-960-9 136426-54-5 single chemical entity Component is a metabolite of the substance 3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione 3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione Not in list C14H7Cl2FN2O2 Clc1ccc(c(Cl)c1)N2C(=O)c3cc(F)ccc3NC2=O InChI=1S/C14H7Cl2FN2O2/c15-7-1-4-12(10(16)5-7)19-13(20)9-6-8(17)2-3-11(9)18-14(19)21/h1-6H,(H,18,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Ireland Fluquinconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole 11May2011 2011 doi:10.2903/j.efsa.2011.2096
+Fluquinconazole 411-960-9 136426-54-5 single chemical entity Component is a metabolite of the substance 3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione 3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione Not in list C14H7Cl2FN2O2 Clc1ccc(c(Cl)c1)N2C(=O)c3cc(F)ccc3NC2=O InChI=1S/C14H7Cl2FN2O2/c15-7-1-4-12(10(16)5-7)19-13(20)9-6-8(17)2-3-11(9)18-14(19)21/h1-6H,(H,18,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Ireland Fluquinconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole 11May2011 2011 doi:10.2903/j.efsa.2011.2096
+Fluquinconazole 411-960-9 136426-54-5 single chemical entity Component is a metabolite of the substance 3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione 3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione Not in list C14H7Cl2FN2O2 Clc1ccc(c(Cl)c1)N2C(=O)c3cc(F)ccc3NC2=O InChI=1S/C14H7Cl2FN2O2/c15-7-1-4-12(10(16)5-7)19-13(20)9-6-8(17)2-3-11(9)18-14(19)21/h1-6H,(H,18,21) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Ireland Fluquinconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole 11May2011 2011 doi:10.2903/j.efsa.2011.2096
+Fluquinconazole 411-960-9 136426-54-5 single chemical entity Component is a metabolite of the substance 3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione 3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione Not in list C14H7Cl2FN2O2 Clc1ccc(c(Cl)c1)N2C(=O)c3cc(F)ccc3NC2=O InChI=1S/C14H7Cl2FN2O2/c15-7-1-4-12(10(16)5-7)19-13(20)9-6-8(17)2-3-11(9)18-14(19)21/h1-6H,(H,18,21) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Ireland Fluquinconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole 11May2011 2011 doi:10.2903/j.efsa.2011.2096
+Fluquinconazole 411-960-9 136426-54-5 single chemical entity Component is a metabolite of the substance 3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione 3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione Not in list C14H7Cl2FN2O2 Clc1ccc(c(Cl)c1)N2C(=O)c3cc(F)ccc3NC2=O InChI=1S/C14H7Cl2FN2O2/c15-7-1-4-12(10(16)5-7)19-13(20)9-6-8(17)2-3-11(9)18-14(19)21/h1-6H,(H,18,21) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Ireland Fluquinconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole 11May2011 2011 doi:10.2903/j.efsa.2011.2096
+Fluquinconazole 411-960-9 136426-54-5 single chemical entity Component is a metabolite of the substance 3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione 3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione Not in list C14H7Cl2FN2O2 Clc1ccc(c(Cl)c1)N2C(=O)c3cc(F)ccc3NC2=O InChI=1S/C14H7Cl2FN2O2/c15-7-1-4-12(10(16)5-7)19-13(20)9-6-8(17)2-3-11(9)18-14(19)21/h1-6H,(H,18,21) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Ireland Fluquinconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole 11May2011 2011 doi:10.2903/j.efsa.2011.2096
+Fluquinconazole 411-960-9 136426-54-5 single chemical entity Component is a metabolite of the substance 3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione 3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione Not in list C14H7Cl2FN2O2 Clc1ccc(c(Cl)c1)N2C(=O)c3cc(F)ccc3NC2=O InChI=1S/C14H7Cl2FN2O2/c15-7-1-4-12(10(16)5-7)19-13(20)9-6-8(17)2-3-11(9)18-14(19)21/h1-6H,(H,18,21) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Ireland Fluquinconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole 11May2011 2011 doi:10.2903/j.efsa.2011.2096
+Fluquinconazole 411-960-9 136426-54-5 single chemical entity Component is a metabolite of the substance 3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione 3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione Not in list C14H7Cl2FN2O2 Clc1ccc(c(Cl)c1)N2C(=O)c3cc(F)ccc3NC2=O InChI=1S/C14H7Cl2FN2O2/c15-7-1-4-12(10(16)5-7)19-13(20)9-6-8(17)2-3-11(9)18-14(19)21/h1-6H,(H,18,21) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 30 Male/Female oral: gavage 72.0000000000 h yes not applicable Negative no evidence RMS: Ireland Fluquinconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole 11May2011 2011 doi:10.2903/j.efsa.2011.2096
+Fluquinconazole 411-960-9 136426-54-5 single chemical entity Component is a metabolite of the substance 3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione 3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione Not in list C14H7Cl2FN2O2 Clc1ccc(c(Cl)c1)N2C(=O)c3cc(F)ccc3NC2=O InChI=1S/C14H7Cl2FN2O2/c15-7-1-4-12(10(16)5-7)19-13(20)9-6-8(17)2-3-11(9)18-14(19)21/h1-6H,(H,18,21) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 30 Male/Female oral: gavage 48.0000000000 h yes not applicable Negative no evidence RMS: Ireland Fluquinconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole 11May2011 2011 doi:10.2903/j.efsa.2011.2096
+Fluquinconazole 411-960-9 136426-54-5 single chemical entity Component is a metabolite of the substance 3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione 3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione Not in list C14H7Cl2FN2O2 Clc1ccc(c(Cl)c1)N2C(=O)c3cc(F)ccc3NC2=O InChI=1S/C14H7Cl2FN2O2/c15-7-1-4-12(10(16)5-7)19-13(20)9-6-8(17)2-3-11(9)18-14(19)21/h1-6H,(H,18,21) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 30 Male/Female oral: gavage 24.0000000000 h yes not applicable Negative no evidence RMS: Ireland Fluquinconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole 11May2011 2011 doi:10.2903/j.efsa.2011.2096
+Flumioxazin 103361-09-7 single chemical entity Component is identical to the substance Flumioxazin 103361-09-7 N-(7-fluoro-3,4-dihydro-3-oxo-4-prop-2-ynyl-2H-1,4-benzoxazin-6-yl)cyclohex-1-ene-1,2-dicarboxamide Flumioxazine C19H15FN2O4 C#CCN1C(=O)COC2=CC(=C(C=C21)N3C(=O)C4=C(C3=O)CCCC4)F InChI=1S/C19H15FN2O4/c1-2-7-21-15-9-14(13(20)8-16(15)26-10-17(21)23)22-18(24)11-5-3-4-6-12(11)19(22)25/h1,8-9H,3-7,10H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: France Flumioxazin (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flumioxazin 12Jun2014 2014 doi:10.2903/j.efsa.2014.3736
+Flumioxazin 103361-09-7 single chemical entity Component is identical to the substance Flumioxazin 103361-09-7 N-(7-fluoro-3,4-dihydro-3-oxo-4-prop-2-ynyl-2H-1,4-benzoxazin-6-yl)cyclohex-1-ene-1,2-dicarboxamide Flumioxazine C19H15FN2O4 C#CCN1C(=O)COC2=CC(=C(C=C21)N3C(=O)C4=C(C3=O)CCCC4)F InChI=1S/C19H15FN2O4/c1-2-7-21-15-9-14(13(20)8-16(15)26-10-17(21)23)22-18(24)11-5-3-4-6-12(11)19(22)25/h1,8-9H,3-7,10H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: France Flumioxazin (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flumioxazin 12Jun2014 2014 doi:10.2903/j.efsa.2014.3736
+Flumioxazin 103361-09-7 single chemical entity Component is identical to the substance Flumioxazin 103361-09-7 N-(7-fluoro-3,4-dihydro-3-oxo-4-prop-2-ynyl-2H-1,4-benzoxazin-6-yl)cyclohex-1-ene-1,2-dicarboxamide Flumioxazine C19H15FN2O4 C#CCN1C(=O)COC2=CC(=C(C=C21)N3C(=O)C4=C(C3=O)CCCC4)F InChI=1S/C19H15FN2O4/c1-2-7-21-15-9-14(13(20)8-16(15)26-10-17(21)23)22-18(24)11-5-3-4-6-12(11)19(22)25/h1,8-9H,3-7,10H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: France Flumioxazin (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flumioxazin 12Jun2014 2014 doi:10.2903/j.efsa.2014.3736
+Flumioxazin 103361-09-7 single chemical entity Component is identical to the substance Flumioxazin 103361-09-7 N-(7-fluoro-3,4-dihydro-3-oxo-4-prop-2-ynyl-2H-1,4-benzoxazin-6-yl)cyclohex-1-ene-1,2-dicarboxamide Flumioxazine C19H15FN2O4 C#CCN1C(=O)COC2=CC(=C(C=C21)N3C(=O)C4=C(C3=O)CCCC4)F InChI=1S/C19H15FN2O4/c1-2-7-21-15-9-14(13(20)8-16(15)26-10-17(21)23)22-18(24)11-5-3-4-6-12(11)19(22)25/h1,8-9H,3-7,10H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: France Flumioxazin (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flumioxazin 12Jun2014 2014 doi:10.2903/j.efsa.2014.3736
+Flumioxazin 103361-09-7 single chemical entity Component is identical to the substance Flumioxazin 103361-09-7 N-(7-fluoro-3,4-dihydro-3-oxo-4-prop-2-ynyl-2H-1,4-benzoxazin-6-yl)cyclohex-1-ene-1,2-dicarboxamide Flumioxazine C19H15FN2O4 C#CCN1C(=O)COC2=CC(=C(C=C21)N3C(=O)C4=C(C3=O)CCCC4)F InChI=1S/C19H15FN2O4/c1-2-7-21-15-9-14(13(20)8-16(15)26-10-17(21)23)22-18(24)11-5-3-4-6-12(11)19(22)25/h1,8-9H,3-7,10H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: France Flumioxazin (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flumioxazin 12Jun2014 2014 doi:10.2903/j.efsa.2014.3736
+Flumioxazin 103361-09-7 single chemical entity Component is identical to the substance Flumioxazin 103361-09-7 N-(7-fluoro-3,4-dihydro-3-oxo-4-prop-2-ynyl-2H-1,4-benzoxazin-6-yl)cyclohex-1-ene-1,2-dicarboxamide Flumioxazine C19H15FN2O4 C#CCN1C(=O)COC2=CC(=C(C=C21)N3C(=O)C4=C(C3=O)CCCC4)F InChI=1S/C19H15FN2O4/c1-2-7-21-15-9-14(13(20)8-16(15)26-10-17(21)23)22-18(24)11-5-3-4-6-12(11)19(22)25/h1,8-9H,3-7,10H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: France Flumioxazin (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flumioxazin 12Jun2014 2014 doi:10.2903/j.efsa.2014.3736
+Flumioxazin 103361-09-7 single chemical entity Component is identical to the substance Flumioxazin 103361-09-7 N-(7-fluoro-3,4-dihydro-3-oxo-4-prop-2-ynyl-2H-1,4-benzoxazin-6-yl)cyclohex-1-ene-1,2-dicarboxamide Flumioxazine C19H15FN2O4 C#CCN1C(=O)COC2=CC(=C(C=C21)N3C(=O)C4=C(C3=O)CCCC4)F InChI=1S/C19H15FN2O4/c1-2-7-21-15-9-14(13(20)8-16(15)26-10-17(21)23)22-18(24)11-5-3-4-6-12(11)19(22)25/h1,8-9H,3-7,10H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: France Flumioxazin (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flumioxazin 12Jun2014 2014 doi:10.2903/j.efsa.2014.3736
+Flumioxazin 103361-09-7 single chemical entity Component is identical to the substance Flumioxazin 103361-09-7 N-(7-fluoro-3,4-dihydro-3-oxo-4-prop-2-ynyl-2H-1,4-benzoxazin-6-yl)cyclohex-1-ene-1,2-dicarboxamide Flumioxazine C19H15FN2O4 C#CCN1C(=O)COC2=CC(=C(C=C21)N3C(=O)C4=C(C3=O)CCCC4)F InChI=1S/C19H15FN2O4/c1-2-7-21-15-9-14(13(20)8-16(15)26-10-17(21)23)22-18(24)11-5-3-4-6-12(11)19(22)25/h1,8-9H,3-7,10H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: France Flumioxazin (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flumioxazin 12Jun2014 2014 doi:10.2903/j.efsa.2014.3736
+Flumioxazin 103361-09-7 single chemical entity Component is identical to the substance Flumioxazin 103361-09-7 N-(7-fluoro-3,4-dihydro-3-oxo-4-prop-2-ynyl-2H-1,4-benzoxazin-6-yl)cyclohex-1-ene-1,2-dicarboxamide Flumioxazine C19H15FN2O4 C#CCN1C(=O)COC2=CC(=C(C=C21)N3C(=O)C4=C(C3=O)CCCC4)F InChI=1S/C19H15FN2O4/c1-2-7-21-15-9-14(13(20)8-16(15)26-10-17(21)23)22-18(24)11-5-3-4-6-12(11)19(22)25/h1,8-9H,3-7,10H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: France Flumioxazin (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flumioxazin 12Jun2014 2014 doi:10.2903/j.efsa.2014.3736
+Flumioxazin 103361-09-7 single chemical entity Component is identical to the substance Flumioxazin 103361-09-7 N-(7-fluoro-3,4-dihydro-3-oxo-4-prop-2-ynyl-2H-1,4-benzoxazin-6-yl)cyclohex-1-ene-1,2-dicarboxamide Flumioxazine C19H15FN2O4 C#CCN1C(=O)COC2=CC(=C(C=C21)N3C(=O)C4=C(C3=O)CCCC4)F InChI=1S/C19H15FN2O4/c1-2-7-21-15-9-14(13(20)8-16(15)26-10-17(21)23)22-18(24)11-5-3-4-6-12(11)19(22)25/h1,8-9H,3-7,10H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: France Flumioxazin (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flumioxazin 12Jun2014 2014 doi:10.2903/j.efsa.2014.3736
+Flumioxazin 103361-09-7 single chemical entity Component is identical to the substance Flumioxazin 103361-09-7 N-(7-fluoro-3,4-dihydro-3-oxo-4-prop-2-ynyl-2H-1,4-benzoxazin-6-yl)cyclohex-1-ene-1,2-dicarboxamide Flumioxazine C19H15FN2O4 C#CCN1C(=O)COC2=CC(=C(C=C21)N3C(=O)C4=C(C3=O)CCCC4)F InChI=1S/C19H15FN2O4/c1-2-7-21-15-9-14(13(20)8-16(15)26-10-17(21)23)22-18(24)11-5-3-4-6-12(11)19(22)25/h1,8-9H,3-7,10H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: France Flumioxazin (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flumioxazin 12Jun2014 2014 doi:10.2903/j.efsa.2014.3736
+Flumioxazin 103361-09-7 single chemical entity Component is identical to the substance Flumioxazin 103361-09-7 N-(7-fluoro-3,4-dihydro-3-oxo-4-prop-2-ynyl-2H-1,4-benzoxazin-6-yl)cyclohex-1-ene-1,2-dicarboxamide Flumioxazine C19H15FN2O4 C#CCN1C(=O)COC2=CC(=C(C=C21)N3C(=O)C4=C(C3=O)CCCC4)F InChI=1S/C19H15FN2O4/c1-2-7-21-15-9-14(13(20)8-16(15)26-10-17(21)23)22-18(24)11-5-3-4-6-12(11)19(22)25/h1,8-9H,3-7,10H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: France Flumioxazin (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flumioxazin 12Jun2014 2014 doi:10.2903/j.efsa.2014.3736
+Flumioxazin 103361-09-7 single chemical entity Component is identical to the substance Flumioxazin 103361-09-7 N-(7-fluoro-3,4-dihydro-3-oxo-4-prop-2-ynyl-2H-1,4-benzoxazin-6-yl)cyclohex-1-ene-1,2-dicarboxamide Flumioxazine C19H15FN2O4 C#CCN1C(=O)COC2=CC(=C(C=C21)N3C(=O)C4=C(C3=O)CCCC4)F InChI=1S/C19H15FN2O4/c1-2-7-21-15-9-14(13(20)8-16(15)26-10-17(21)23)22-18(24)11-5-3-4-6-12(11)19(22)25/h1,8-9H,3-7,10H2 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported no data with Positive RMS: France Flumioxazin (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flumioxazin 12Jun2014 2014 doi:10.2903/j.efsa.2014.3736
+Flumioxazin 103361-09-7 single chemical entity Component is identical to the substance Flumioxazin 103361-09-7 N-(7-fluoro-3,4-dihydro-3-oxo-4-prop-2-ynyl-2H-1,4-benzoxazin-6-yl)cyclohex-1-ene-1,2-dicarboxamide Flumioxazine C19H15FN2O4 C#CCN1C(=O)COC2=CC(=C(C=C21)N3C(=O)C4=C(C3=O)CCCC4)F InChI=1S/C19H15FN2O4/c1-2-7-21-15-9-14(13(20)8-16(15)26-10-17(21)23)22-18(24)11-5-3-4-6-12(11)19(22)25/h1,8-9H,3-7,10H2 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported no data without Negative RMS: France Flumioxazin (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flumioxazin 12Jun2014 2014 doi:10.2903/j.efsa.2014.3736
+Flumioxazin 103361-09-7 single chemical entity Component is identical to the substance Flumioxazin 103361-09-7 N-(7-fluoro-3,4-dihydro-3-oxo-4-prop-2-ynyl-2H-1,4-benzoxazin-6-yl)cyclohex-1-ene-1,2-dicarboxamide Flumioxazine C19H15FN2O4 C#CCN1C(=O)COC2=CC(=C(C=C21)N3C(=O)C4=C(C3=O)CCCC4)F InChI=1S/C19H15FN2O4/c1-2-7-21-15-9-14(13(20)8-16(15)26-10-17(21)23)22-18(24)11-5-3-4-6-12(11)19(22)25/h1,8-9H,3-7,10H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: France Flumioxazin (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flumioxazin 12Jun2014 2014 doi:10.2903/j.efsa.2014.3736
+Flumioxazin 103361-09-7 single chemical entity Component is identical to the substance Flumioxazin 103361-09-7 N-(7-fluoro-3,4-dihydro-3-oxo-4-prop-2-ynyl-2H-1,4-benzoxazin-6-yl)cyclohex-1-ene-1,2-dicarboxamide Flumioxazine C19H15FN2O4 C#CCN1C(=O)COC2=CC(=C(C=C21)N3C(=O)C4=C(C3=O)CCCC4)F InChI=1S/C19H15FN2O4/c1-2-7-21-15-9-14(13(20)8-16(15)26-10-17(21)23)22-18(24)11-5-3-4-6-12(11)19(22)25/h1,8-9H,3-7,10H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: France Flumioxazin (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flumioxazin 12Jun2014 2014 doi:10.2903/j.efsa.2014.3736
+Flumioxazin 103361-09-7 single chemical entity Component is identical to the substance Flumioxazin 103361-09-7 N-(7-fluoro-3,4-dihydro-3-oxo-4-prop-2-ynyl-2H-1,4-benzoxazin-6-yl)cyclohex-1-ene-1,2-dicarboxamide Flumioxazine C19H15FN2O4 C#CCN1C(=O)COC2=CC(=C(C=C21)N3C(=O)C4=C(C3=O)CCCC4)F InChI=1S/C19H15FN2O4/c1-2-7-21-15-9-14(13(20)8-16(15)26-10-17(21)23)22-18(24)11-5-3-4-6-12(11)19(22)25/h1,8-9H,3-7,10H2 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) ICR No data intraperitoneal no data not applicable Negative no evidence RMS: France Flumioxazin (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flumioxazin 12Jun2014 2014 doi:10.2903/j.efsa.2014.3736
+Flumioxazin 103361-09-7 single chemical entity Component is identical to the substance Flumioxazin 103361-09-7 N-(7-fluoro-3,4-dihydro-3-oxo-4-prop-2-ynyl-2H-1,4-benzoxazin-6-yl)cyclohex-1-ene-1,2-dicarboxamide Flumioxazine C19H15FN2O4 C#CCN1C(=O)COC2=CC(=C(C=C21)N3C(=O)C4=C(C3=O)CCCC4)F InChI=1S/C19H15FN2O4/c1-2-7-21-15-9-14(13(20)8-16(15)26-10-17(21)23)22-18(24)11-5-3-4-6-12(11)19(22)25/h1,8-9H,3-7,10H2 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Rat (as animal) Sprague-Dawley No data oral: gavage no data not applicable Negative RMS: France Flumioxazin (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flumioxazin 12Jun2014 2014 doi:10.2903/j.efsa.2014.3736
+Flumioxazin 103361-09-7 single chemical entity Component is identical to the substance Flumioxazin 103361-09-7 N-(7-fluoro-3,4-dihydro-3-oxo-4-prop-2-ynyl-2H-1,4-benzoxazin-6-yl)cyclohex-1-ene-1,2-dicarboxamide Flumioxazine C19H15FN2O4 C#CCN1C(=O)COC2=CC(=C(C=C21)N3C(=O)C4=C(C3=O)CCCC4)F InChI=1S/C19H15FN2O4/c1-2-7-21-15-9-14(13(20)8-16(15)26-10-17(21)23)22-18(24)11-5-3-4-6-12(11)19(22)25/h1,8-9H,3-7,10H2 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Sprague-Dawley No data oral: unspecified no data not applicable Negative RMS: France Flumioxazin (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flumioxazin 12Jun2014 2014 doi:10.2903/j.efsa.2014.3736
+Quinmerac 90717-03-6 single chemical entity Component is identical to the substance Quinmerac 90717-03-6 7-chloro-3-methylquinoline-8-carboxylic acid Quinmerac C11H8ClNO2 O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2 InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Quinmerac 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac 29Mar2010 2010 doi:10.2903/j.efsa.2010.1523
+Quinmerac 90717-03-6 single chemical entity Component is identical to the substance Quinmerac 90717-03-6 7-chloro-3-methylquinoline-8-carboxylic acid Quinmerac C11H8ClNO2 O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2 InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Quinmerac 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac 29Mar2010 2010 doi:10.2903/j.efsa.2010.1523
+Quinmerac 90717-03-6 single chemical entity Component is identical to the substance Quinmerac 90717-03-6 7-chloro-3-methylquinoline-8-carboxylic acid Quinmerac C11H8ClNO2 O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2 InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Quinmerac 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac 29Mar2010 2010 doi:10.2903/j.efsa.2010.1523
+Quinmerac 90717-03-6 single chemical entity Component is identical to the substance Quinmerac 90717-03-6 7-chloro-3-methylquinoline-8-carboxylic acid Quinmerac C11H8ClNO2 O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2 InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Quinmerac 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac 29Mar2010 2010 doi:10.2903/j.efsa.2010.1523
+Quinmerac 90717-03-6 single chemical entity Component is identical to the substance Quinmerac 90717-03-6 7-chloro-3-methylquinoline-8-carboxylic acid Quinmerac C11H8ClNO2 O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2 InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Quinmerac 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac 29Mar2010 2010 doi:10.2903/j.efsa.2010.1523
+Quinmerac 90717-03-6 single chemical entity Component is identical to the substance Quinmerac 90717-03-6 7-chloro-3-methylquinoline-8-carboxylic acid Quinmerac C11H8ClNO2 O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2 InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Quinmerac 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac 29Mar2010 2010 doi:10.2903/j.efsa.2010.1523
+Quinmerac 90717-03-6 single chemical entity Component is identical to the substance Quinmerac 90717-03-6 7-chloro-3-methylquinoline-8-carboxylic acid Quinmerac C11H8ClNO2 O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2 InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Quinmerac 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac 29Mar2010 2010 doi:10.2903/j.efsa.2010.1523
+Quinmerac 90717-03-6 single chemical entity Component is identical to the substance Quinmerac 90717-03-6 7-chloro-3-methylquinoline-8-carboxylic acid Quinmerac C11H8ClNO2 O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2 InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Quinmerac 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac 29Mar2010 2010 doi:10.2903/j.efsa.2010.1523
+Quinmerac 90717-03-6 single chemical entity Component is identical to the substance Quinmerac 90717-03-6 7-chloro-3-methylquinoline-8-carboxylic acid Quinmerac C11H8ClNO2 O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2 InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Quinmerac 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac 29Mar2010 2010 doi:10.2903/j.efsa.2010.1523
+Quinmerac 90717-03-6 single chemical entity Component is identical to the substance Quinmerac 90717-03-6 7-chloro-3-methylquinoline-8-carboxylic acid Quinmerac C11H8ClNO2 O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2 InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Quinmerac 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac 29Mar2010 2010 doi:10.2903/j.efsa.2010.1523
+Quinmerac 90717-03-6 single chemical entity Component is identical to the substance Quinmerac 90717-03-6 7-chloro-3-methylquinoline-8-carboxylic acid Quinmerac C11H8ClNO2 O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2 InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Quinmerac 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac 29Mar2010 2010 doi:10.2903/j.efsa.2010.1523
+Quinmerac 90717-03-6 single chemical entity Component is identical to the substance Quinmerac 90717-03-6 7-chloro-3-methylquinoline-8-carboxylic acid Quinmerac C11H8ClNO2 O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2 InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Quinmerac 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac 29Mar2010 2010 doi:10.2903/j.efsa.2010.1523
+Quinmerac 90717-03-6 single chemical entity Component is identical to the substance Quinmerac 90717-03-6 7-chloro-3-methylquinoline-8-carboxylic acid Quinmerac C11H8ClNO2 O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2 InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Quinmerac 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac 29Mar2010 2010 doi:10.2903/j.efsa.2010.1523
+Quinmerac 90717-03-6 single chemical entity Component is identical to the substance Quinmerac 90717-03-6 7-chloro-3-methylquinoline-8-carboxylic acid Quinmerac C11H8ClNO2 O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2 InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Quinmerac 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac 29Mar2010 2010 doi:10.2903/j.efsa.2010.1523
+Quinmerac 90717-03-6 single chemical entity Component is identical to the substance Quinmerac 90717-03-6 7-chloro-3-methylquinoline-8-carboxylic acid Quinmerac C11H8ClNO2 O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2 InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Quinmerac 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac 29Mar2010 2010 doi:10.2903/j.efsa.2010.1523
+Quinmerac 90717-03-6 single chemical entity Component is identical to the substance Quinmerac 90717-03-6 7-chloro-3-methylquinoline-8-carboxylic acid Quinmerac C11H8ClNO2 O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2 InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Quinmerac 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac 29Mar2010 2010 doi:10.2903/j.efsa.2010.1523
+Quinmerac 90717-03-6 single chemical entity Component is identical to the substance Quinmerac 90717-03-6 7-chloro-3-methylquinoline-8-carboxylic acid Quinmerac C11H8ClNO2 O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2 InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Inconclusive RMS: The United Kingdom Quinmerac 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac 29Mar2010 2010 doi:10.2903/j.efsa.2010.1523
+Quinmerac 90717-03-6 single chemical entity Component is identical to the substance Quinmerac 90717-03-6 7-chloro-3-methylquinoline-8-carboxylic acid Quinmerac C11H8ClNO2 O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2 InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Quinmerac 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac 29Mar2010 2010 doi:10.2903/j.efsa.2010.1523
+Quinmerac 90717-03-6 single chemical entity Component is identical to the substance Quinmerac 90717-03-6 7-chloro-3-methylquinoline-8-carboxylic acid Quinmerac C11H8ClNO2 O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2 InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15) organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Quinmerac 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac 29Mar2010 2010 doi:10.2903/j.efsa.2010.1523
+Quinmerac 90717-03-6 single chemical entity Component is identical to the substance Quinmerac 90717-03-6 7-chloro-3-methylquinoline-8-carboxylic acid Quinmerac C11H8ClNO2 O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2 InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15) organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) B6C3F1 10 Male/Female oral: gavage 6.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Quinmerac 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac 29Mar2010 2010 doi:10.2903/j.efsa.2010.1523
+Quinmerac 90717-03-6 single chemical entity Component is identical to the substance Quinmerac 90717-03-6 7-chloro-3-methylquinoline-8-carboxylic acid Quinmerac C11H8ClNO2 O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2 InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15) organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) B6C3F1 10 Male/Female oral: gavage 30.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Quinmerac 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac 29Mar2010 2010 doi:10.2903/j.efsa.2010.1523
+Quinmerac 90717-03-6 single chemical entity Component is identical to the substance Quinmerac 90717-03-6 7-chloro-3-methylquinoline-8-carboxylic acid Quinmerac C11H8ClNO2 O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2 InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15) organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable House mouse (as animal) B6C3F1 10 Male/Female oral: gavage 18.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Quinmerac 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac 29Mar2010 2010 doi:10.2903/j.efsa.2010.1523
+Quinmerac 90717-03-6 single chemical entity Component is identical to the substance Quinmerac 90717-03-6 7-chloro-3-methylquinoline-8-carboxylic acid Quinmerac C11H8ClNO2 O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2 InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: The United Kingdom Quinmerac (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac 29Mar2010 2010 doi:10.2903/j.efsa.2010.1523
+Quinmerac 90717-03-6 single chemical entity Component is identical to the substance Quinmerac 90717-03-6 7-chloro-3-methylquinoline-8-carboxylic acid Quinmerac C11H8ClNO2 O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2 InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: The United Kingdom Quinmerac (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac 29Mar2010 2010 doi:10.2903/j.efsa.2010.1523
+Quinmerac 90717-03-6 single chemical entity Component is identical to the substance Quinmerac 90717-03-6 7-chloro-3-methylquinoline-8-carboxylic acid Quinmerac C11H8ClNO2 O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2 InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: The United Kingdom Quinmerac (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac 29Mar2010 2010 doi:10.2903/j.efsa.2010.1523
+Quinmerac 90717-03-6 single chemical entity Component is identical to the substance Quinmerac 90717-03-6 7-chloro-3-methylquinoline-8-carboxylic acid Quinmerac C11H8ClNO2 O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2 InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: The United Kingdom Quinmerac (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac 29Mar2010 2010 doi:10.2903/j.efsa.2010.1523
+Quinmerac 90717-03-6 single chemical entity Component is identical to the substance Quinmerac 90717-03-6 7-chloro-3-methylquinoline-8-carboxylic acid Quinmerac C11H8ClNO2 O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2 InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: The United Kingdom Quinmerac (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac 29Mar2010 2010 doi:10.2903/j.efsa.2010.1523
+Quinmerac 90717-03-6 single chemical entity Component is identical to the substance Quinmerac 90717-03-6 7-chloro-3-methylquinoline-8-carboxylic acid Quinmerac C11H8ClNO2 O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2 InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: The United Kingdom Quinmerac (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac 29Mar2010 2010 doi:10.2903/j.efsa.2010.1523
+Quinmerac 90717-03-6 single chemical entity Component is identical to the substance Quinmerac 90717-03-6 7-chloro-3-methylquinoline-8-carboxylic acid Quinmerac C11H8ClNO2 O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2 InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: The United Kingdom Quinmerac (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac 29Mar2010 2010 doi:10.2903/j.efsa.2010.1523
+Quinmerac 90717-03-6 single chemical entity Component is identical to the substance Quinmerac 90717-03-6 7-chloro-3-methylquinoline-8-carboxylic acid Quinmerac C11H8ClNO2 O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2 InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: The United Kingdom Quinmerac (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac 29Mar2010 2010 doi:10.2903/j.efsa.2010.1523
+Quinmerac 90717-03-6 single chemical entity Component is identical to the substance Quinmerac 90717-03-6 7-chloro-3-methylquinoline-8-carboxylic acid Quinmerac C11H8ClNO2 O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2 InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: The United Kingdom Quinmerac (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac 29Mar2010 2010 doi:10.2903/j.efsa.2010.1523
+Quinmerac 90717-03-6 single chemical entity Component is identical to the substance Quinmerac 90717-03-6 7-chloro-3-methylquinoline-8-carboxylic acid Quinmerac C11H8ClNO2 O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2 InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: The United Kingdom Quinmerac (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac 29Mar2010 2010 doi:10.2903/j.efsa.2010.1523
+Quinmerac 90717-03-6 single chemical entity Component is identical to the substance Quinmerac 90717-03-6 7-chloro-3-methylquinoline-8-carboxylic acid Quinmerac C11H8ClNO2 O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2 InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative small colonies RMS: The United Kingdom Quinmerac (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac 29Mar2010 2010 doi:10.2903/j.efsa.2010.1523
+Quinmerac 90717-03-6 single chemical entity Component is identical to the substance Quinmerac 90717-03-6 7-chloro-3-methylquinoline-8-carboxylic acid Quinmerac C11H8ClNO2 O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2 InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative large colonies RMS: The United Kingdom Quinmerac (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac 29Mar2010 2010 doi:10.2903/j.efsa.2010.1523
+Quinmerac 90717-03-6 single chemical entity Component is identical to the substance Quinmerac 90717-03-6 7-chloro-3-methylquinoline-8-carboxylic acid Quinmerac C11H8ClNO2 O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2 InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative small colonies RMS: The United Kingdom Quinmerac (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac 29Mar2010 2010 doi:10.2903/j.efsa.2010.1523
+Quinmerac 90717-03-6 single chemical entity Component is identical to the substance Quinmerac 90717-03-6 7-chloro-3-methylquinoline-8-carboxylic acid Quinmerac C11H8ClNO2 O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2 InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative large colonies RMS: The United Kingdom Quinmerac (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac 29Mar2010 2010 doi:10.2903/j.efsa.2010.1523
+Quinmerac 90717-03-6 single chemical entity Component is a metabolite of the substance 7-chloro-2-hydroxy-3-methylquinoline-8-carboxylic acid 7-chloro-2-hydroxy-3-methylquinoline-8-carboxylic acid Not in list C11H8ClNO3 OC(=O)c1c(Cl)ccc2cc(C)c(O)nc12 InChI=1/C11H8ClNO3/c1-5-4-6-2-3-7(12)8(11(15)16)9(6)13-10(5)14/h2-4H,1H3,(H,13,14)(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Quinmerac 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac 29Mar2010 2010 doi:10.2903/j.efsa.2010.1523
+Quinmerac 90717-03-6 single chemical entity Component is a metabolite of the substance 7-chloro-2-hydroxy-3-methylquinoline-8-carboxylic acid 7-chloro-2-hydroxy-3-methylquinoline-8-carboxylic acid Not in list C11H8ClNO3 OC(=O)c1c(Cl)ccc2cc(C)c(O)nc12 InChI=1/C11H8ClNO3/c1-5-4-6-2-3-7(12)8(11(15)16)9(6)13-10(5)14/h2-4H,1H3,(H,13,14)(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Quinmerac 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac 29Mar2010 2010 doi:10.2903/j.efsa.2010.1523
+Quinmerac 90717-03-6 single chemical entity Component is a metabolite of the substance 7-chloro-2-hydroxy-3-methylquinoline-8-carboxylic acid 7-chloro-2-hydroxy-3-methylquinoline-8-carboxylic acid Not in list C11H8ClNO3 OC(=O)c1c(Cl)ccc2cc(C)c(O)nc12 InChI=1/C11H8ClNO3/c1-5-4-6-2-3-7(12)8(11(15)16)9(6)13-10(5)14/h2-4H,1H3,(H,13,14)(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Quinmerac 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac 29Mar2010 2010 doi:10.2903/j.efsa.2010.1523
+Quinmerac 90717-03-6 single chemical entity Component is a metabolite of the substance 7-chloro-2-hydroxy-3-methylquinoline-8-carboxylic acid 7-chloro-2-hydroxy-3-methylquinoline-8-carboxylic acid Not in list C11H8ClNO3 OC(=O)c1c(Cl)ccc2cc(C)c(O)nc12 InChI=1/C11H8ClNO3/c1-5-4-6-2-3-7(12)8(11(15)16)9(6)13-10(5)14/h2-4H,1H3,(H,13,14)(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Quinmerac 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac 29Mar2010 2010 doi:10.2903/j.efsa.2010.1523
+Quinmerac 90717-03-6 single chemical entity Component is a metabolite of the substance 7-chloro-2-hydroxy-3-methylquinoline-8-carboxylic acid 7-chloro-2-hydroxy-3-methylquinoline-8-carboxylic acid Not in list C11H8ClNO3 OC(=O)c1c(Cl)ccc2cc(C)c(O)nc12 InChI=1/C11H8ClNO3/c1-5-4-6-2-3-7(12)8(11(15)16)9(6)13-10(5)14/h2-4H,1H3,(H,13,14)(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Quinmerac 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac 29Mar2010 2010 doi:10.2903/j.efsa.2010.1523
+Quinmerac 90717-03-6 single chemical entity Component is a metabolite of the substance 7-chloro-2-hydroxy-3-methylquinoline-8-carboxylic acid 7-chloro-2-hydroxy-3-methylquinoline-8-carboxylic acid Not in list C11H8ClNO3 OC(=O)c1c(Cl)ccc2cc(C)c(O)nc12 InChI=1/C11H8ClNO3/c1-5-4-6-2-3-7(12)8(11(15)16)9(6)13-10(5)14/h2-4H,1H3,(H,13,14)(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Quinmerac 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac 29Mar2010 2010 doi:10.2903/j.efsa.2010.1523
+Quinmerac 90717-03-6 single chemical entity Component is a metabolite of the substance 7-chloro-2-hydroxy-3-methylquinoline-8-carboxylic acid 7-chloro-2-hydroxy-3-methylquinoline-8-carboxylic acid Not in list C11H8ClNO3 OC(=O)c1c(Cl)ccc2cc(C)c(O)nc12 InChI=1/C11H8ClNO3/c1-5-4-6-2-3-7(12)8(11(15)16)9(6)13-10(5)14/h2-4H,1H3,(H,13,14)(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Quinmerac 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac 29Mar2010 2010 doi:10.2903/j.efsa.2010.1523
+Quinmerac 90717-03-6 single chemical entity Component is a metabolite of the substance 7-chloro-2-hydroxy-3-methylquinoline-8-carboxylic acid 7-chloro-2-hydroxy-3-methylquinoline-8-carboxylic acid Not in list C11H8ClNO3 OC(=O)c1c(Cl)ccc2cc(C)c(O)nc12 InChI=1/C11H8ClNO3/c1-5-4-6-2-3-7(12)8(11(15)16)9(6)13-10(5)14/h2-4H,1H3,(H,13,14)(H,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Quinmerac 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac 29Mar2010 2010 doi:10.2903/j.efsa.2010.1523
+Quinmerac 90717-03-6 single chemical entity Component is a metabolite of the substance 7-chloro-2-hydroxy-3-methylquinoline-8-carboxylic acid 7-chloro-2-hydroxy-3-methylquinoline-8-carboxylic acid Not in list C11H8ClNO3 OC(=O)c1c(Cl)ccc2cc(C)c(O)nc12 InChI=1/C11H8ClNO3/c1-5-4-6-2-3-7(12)8(11(15)16)9(6)13-10(5)14/h2-4H,1H3,(H,13,14)(H,15,16) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Inconclusive RMS: The United Kingdom Quinmerac 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac 29Mar2010 2010 doi:10.2903/j.efsa.2010.1523
+Quinmerac 90717-03-6 single chemical entity Component is a metabolite of the substance 7-chloro-2-hydroxy-3-methylquinoline-8-carboxylic acid 7-chloro-2-hydroxy-3-methylquinoline-8-carboxylic acid Not in list C11H8ClNO3 OC(=O)c1c(Cl)ccc2cc(C)c(O)nc12 InChI=1/C11H8ClNO3/c1-5-4-6-2-3-7(12)8(11(15)16)9(6)13-10(5)14/h2-4H,1H3,(H,13,14)(H,15,16) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Inconclusive RMS: The United Kingdom Quinmerac 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac 29Mar2010 2010 doi:10.2903/j.efsa.2010.1523
+Quinmerac 90717-03-6 single chemical entity Component is a metabolite of the substance 7-chloro-2-hydroxy-3-methylquinoline-8-carboxylic acid 7-chloro-2-hydroxy-3-methylquinoline-8-carboxylic acid Not in list C11H8ClNO3 OC(=O)c1c(Cl)ccc2cc(C)c(O)nc12 InChI=1/C11H8ClNO3/c1-5-4-6-2-3-7(12)8(11(15)16)9(6)13-10(5)14/h2-4H,1H3,(H,13,14)(H,15,16) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 72.0000000000 h yes not applicable Negative indirect-toxicokinetic investigations RMS: The United Kingdom Quinmerac 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac 29Mar2010 2010 doi:10.2903/j.efsa.2010.1523
+Quinmerac 90717-03-6 single chemical entity Component is a metabolite of the substance 7-chloro-2-hydroxy-3-methylquinoline-8-carboxylic acid 7-chloro-2-hydroxy-3-methylquinoline-8-carboxylic acid Not in list C11H8ClNO3 OC(=O)c1c(Cl)ccc2cc(C)c(O)nc12 InChI=1/C11H8ClNO3/c1-5-4-6-2-3-7(12)8(11(15)16)9(6)13-10(5)14/h2-4H,1H3,(H,13,14)(H,15,16) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes not applicable Negative indirect-toxicokinetic investigations RMS: The United Kingdom Quinmerac 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac 29Mar2010 2010 doi:10.2903/j.efsa.2010.1523
+Quinmerac 90717-03-6 single chemical entity Component is a metabolite of the substance 7-chloro-2-hydroxy-3-methylquinoline-8-carboxylic acid 7-chloro-2-hydroxy-3-methylquinoline-8-carboxylic acid Not in list C11H8ClNO3 OC(=O)c1c(Cl)ccc2cc(C)c(O)nc12 InChI=1/C11H8ClNO3/c1-5-4-6-2-3-7(12)8(11(15)16)9(6)13-10(5)14/h2-4H,1H3,(H,13,14)(H,15,16) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 48.0000000000 h yes not applicable Negative indirect-toxicokinetic investigations RMS: The United Kingdom Quinmerac 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac 29Mar2010 2010 doi:10.2903/j.efsa.2010.1523
+Quinmerac 90717-03-6 single chemical entity Component is a metabolite of the substance 7-chloroquinoline-3,8-dicarboxylic acid 7-chloroquinoline-3,8-dicarboxylic acid Not in list C11H6ClNO4 OC(=O)c1c(Cl)ccc2cc(cnc12)C(O)=O InChI=1/C11H6ClNO4/c12-7-2-1-5-3-6(10(14)15)4-13-9(5)8(7)11(16)17/h1-4H,(H,14,15)(H,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Quinmerac 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac 29Mar2010 2010 doi:10.2903/j.efsa.2010.1523
+Quinmerac 90717-03-6 single chemical entity Component is a metabolite of the substance 7-chloroquinoline-3,8-dicarboxylic acid 7-chloroquinoline-3,8-dicarboxylic acid Not in list C11H6ClNO4 OC(=O)c1c(Cl)ccc2cc(cnc12)C(O)=O InChI=1/C11H6ClNO4/c12-7-2-1-5-3-6(10(14)15)4-13-9(5)8(7)11(16)17/h1-4H,(H,14,15)(H,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Quinmerac 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac 29Mar2010 2010 doi:10.2903/j.efsa.2010.1523
+Quinmerac 90717-03-6 single chemical entity Component is a metabolite of the substance 7-chloroquinoline-3,8-dicarboxylic acid 7-chloroquinoline-3,8-dicarboxylic acid Not in list C11H6ClNO4 OC(=O)c1c(Cl)ccc2cc(cnc12)C(O)=O InChI=1/C11H6ClNO4/c12-7-2-1-5-3-6(10(14)15)4-13-9(5)8(7)11(16)17/h1-4H,(H,14,15)(H,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Positive RMS: The United Kingdom Quinmerac 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac 29Mar2010 2010 doi:10.2903/j.efsa.2010.1523
+Quinmerac 90717-03-6 single chemical entity Component is a metabolite of the substance 7-chloroquinoline-3,8-dicarboxylic acid 7-chloroquinoline-3,8-dicarboxylic acid Not in list C11H6ClNO4 OC(=O)c1c(Cl)ccc2cc(cnc12)C(O)=O InChI=1/C11H6ClNO4/c12-7-2-1-5-3-6(10(14)15)4-13-9(5)8(7)11(16)17/h1-4H,(H,14,15)(H,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Quinmerac 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac 29Mar2010 2010 doi:10.2903/j.efsa.2010.1523
+Quinmerac 90717-03-6 single chemical entity Component is a metabolite of the substance 7-chloroquinoline-3,8-dicarboxylic acid 7-chloroquinoline-3,8-dicarboxylic acid Not in list C11H6ClNO4 OC(=O)c1c(Cl)ccc2cc(cnc12)C(O)=O InChI=1/C11H6ClNO4/c12-7-2-1-5-3-6(10(14)15)4-13-9(5)8(7)11(16)17/h1-4H,(H,14,15)(H,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Quinmerac 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac 29Mar2010 2010 doi:10.2903/j.efsa.2010.1523
+Quinmerac 90717-03-6 single chemical entity Component is a metabolite of the substance 7-chloroquinoline-3,8-dicarboxylic acid 7-chloroquinoline-3,8-dicarboxylic acid Not in list C11H6ClNO4 OC(=O)c1c(Cl)ccc2cc(cnc12)C(O)=O InChI=1/C11H6ClNO4/c12-7-2-1-5-3-6(10(14)15)4-13-9(5)8(7)11(16)17/h1-4H,(H,14,15)(H,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Positive RMS: The United Kingdom Quinmerac 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac 29Mar2010 2010 doi:10.2903/j.efsa.2010.1523
+Quinmerac 90717-03-6 single chemical entity Component is a metabolite of the substance 7-chloroquinoline-3,8-dicarboxylic acid 7-chloroquinoline-3,8-dicarboxylic acid Not in list C11H6ClNO4 OC(=O)c1c(Cl)ccc2cc(cnc12)C(O)=O InChI=1/C11H6ClNO4/c12-7-2-1-5-3-6(10(14)15)4-13-9(5)8(7)11(16)17/h1-4H,(H,14,15)(H,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Positive RMS: The United Kingdom Quinmerac 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac 29Mar2010 2010 doi:10.2903/j.efsa.2010.1523
+Quinmerac 90717-03-6 single chemical entity Component is a metabolite of the substance 7-chloroquinoline-3,8-dicarboxylic acid 7-chloroquinoline-3,8-dicarboxylic acid Not in list C11H6ClNO4 OC(=O)c1c(Cl)ccc2cc(cnc12)C(O)=O InChI=1/C11H6ClNO4/c12-7-2-1-5-3-6(10(14)15)4-13-9(5)8(7)11(16)17/h1-4H,(H,14,15)(H,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Quinmerac 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac 29Mar2010 2010 doi:10.2903/j.efsa.2010.1523
+Quinmerac 90717-03-6 single chemical entity Component is a metabolite of the substance 7-chloroquinoline-3,8-dicarboxylic acid 7-chloroquinoline-3,8-dicarboxylic acid Not in list C11H6ClNO4 OC(=O)c1c(Cl)ccc2cc(cnc12)C(O)=O InChI=1/C11H6ClNO4/c12-7-2-1-5-3-6(10(14)15)4-13-9(5)8(7)11(16)17/h1-4H,(H,14,15)(H,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Quinmerac 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac 29Mar2010 2010 doi:10.2903/j.efsa.2010.1523
+Quinmerac 90717-03-6 single chemical entity Component is a metabolite of the substance 7-chloroquinoline-3,8-dicarboxylic acid 7-chloroquinoline-3,8-dicarboxylic acid Not in list C11H6ClNO4 OC(=O)c1c(Cl)ccc2cc(cnc12)C(O)=O InChI=1/C11H6ClNO4/c12-7-2-1-5-3-6(10(14)15)4-13-9(5)8(7)11(16)17/h1-4H,(H,14,15)(H,16,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Quinmerac 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac 29Mar2010 2010 doi:10.2903/j.efsa.2010.1523
+Quinmerac 90717-03-6 single chemical entity Component is a metabolite of the substance 7-chloroquinoline-3,8-dicarboxylic acid 7-chloroquinoline-3,8-dicarboxylic acid Not in list C11H6ClNO4 OC(=O)c1c(Cl)ccc2cc(cnc12)C(O)=O InChI=1/C11H6ClNO4/c12-7-2-1-5-3-6(10(14)15)4-13-9(5)8(7)11(16)17/h1-4H,(H,14,15)(H,16,17) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Quinmerac 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac 29Mar2010 2010 doi:10.2903/j.efsa.2010.1523
+Quinmerac 90717-03-6 single chemical entity Component is a metabolite of the substance 7-chloroquinoline-3,8-dicarboxylic acid 7-chloroquinoline-3,8-dicarboxylic acid Not in list C11H6ClNO4 OC(=O)c1c(Cl)ccc2cc(cnc12)C(O)=O InChI=1/C11H6ClNO4/c12-7-2-1-5-3-6(10(14)15)4-13-9(5)8(7)11(16)17/h1-4H,(H,14,15)(H,16,17) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Quinmerac 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac 29Mar2010 2010 doi:10.2903/j.efsa.2010.1523
+Quinmerac 90717-03-6 single chemical entity Component is a metabolite of the substance 7-chloroquinoline-3,8-dicarboxylic acid 7-chloroquinoline-3,8-dicarboxylic acid Not in list C11H6ClNO4 OC(=O)c1c(Cl)ccc2cc(cnc12)C(O)=O InChI=1/C11H6ClNO4/c12-7-2-1-5-3-6(10(14)15)4-13-9(5)8(7)11(16)17/h1-4H,(H,14,15)(H,16,17) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 5 Male oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect-toxicokinetic investigations RMS: The United Kingdom Quinmerac 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac 29Mar2010 2010 doi:10.2903/j.efsa.2010.1523
+Quinmerac 90717-03-6 single chemical entity Component is a metabolite of the substance 7-chloroquinoline-3,8-dicarboxylic acid 7-chloroquinoline-3,8-dicarboxylic acid Not in list C11H6ClNO4 OC(=O)c1c(Cl)ccc2cc(cnc12)C(O)=O InChI=1/C11H6ClNO4/c12-7-2-1-5-3-6(10(14)15)4-13-9(5)8(7)11(16)17/h1-4H,(H,14,15)(H,16,17) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Negative no information RMS: The United Kingdom Quinmerac (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac 29Mar2010 2010 doi:10.2903/j.efsa.2010.1523
+Quinmerac 90717-03-6 single chemical entity Component is a metabolite of the substance 7-chloroquinoline-3,8-dicarboxylic acid 7-chloroquinoline-3,8-dicarboxylic acid Not in list C11H6ClNO4 OC(=O)c1c(Cl)ccc2cc(cnc12)C(O)=O InChI=1/C11H6ClNO4/c12-7-2-1-5-3-6(10(14)15)4-13-9(5)8(7)11(16)17/h1-4H,(H,14,15)(H,16,17) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative no information RMS: The United Kingdom Quinmerac (Additional report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac 29Mar2010 2010 doi:10.2903/j.efsa.2010.1523
+Sulfoxaflor 946578-00-3 single chemical entity Component is identical to the substance Sulfoxaflor 946578-00-3 [methyl-oxo-[1-[6(trifluoromethyl)pyridin-3-yl]ethyl]-λ{6}-sulfanylidene]cyanamide Not in list C10H10F3N3OS CC(C1=CN=C(C=C1)C(F)(F)F)S(=NC#N)(=O)C InChI=1S/C10H10F3N3OS/c1-7(18(2,17)16-6-14)8-3-4-9(15-5-8)10(11,12)13/h3-5,7H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is identical to the substance Sulfoxaflor 946578-00-3 [methyl-oxo-[1-[6(trifluoromethyl)pyridin-3-yl]ethyl]-λ{6}-sulfanylidene]cyanamide Not in list C10H10F3N3OS CC(C1=CN=C(C=C1)C(F)(F)F)S(=NC#N)(=O)C InChI=1S/C10H10F3N3OS/c1-7(18(2,17)16-6-14)8-3-4-9(15-5-8)10(11,12)13/h3-5,7H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is identical to the substance Sulfoxaflor 946578-00-3 [methyl-oxo-[1-[6(trifluoromethyl)pyridin-3-yl]ethyl]-λ{6}-sulfanylidene]cyanamide Not in list C10H10F3N3OS CC(C1=CN=C(C=C1)C(F)(F)F)S(=NC#N)(=O)C InChI=1S/C10H10F3N3OS/c1-7(18(2,17)16-6-14)8-3-4-9(15-5-8)10(11,12)13/h3-5,7H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is identical to the substance Sulfoxaflor 946578-00-3 [methyl-oxo-[1-[6(trifluoromethyl)pyridin-3-yl]ethyl]-λ{6}-sulfanylidene]cyanamide Not in list C10H10F3N3OS CC(C1=CN=C(C=C1)C(F)(F)F)S(=NC#N)(=O)C InChI=1S/C10H10F3N3OS/c1-7(18(2,17)16-6-14)8-3-4-9(15-5-8)10(11,12)13/h3-5,7H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is identical to the substance Sulfoxaflor 946578-00-3 [methyl-oxo-[1-[6(trifluoromethyl)pyridin-3-yl]ethyl]-λ{6}-sulfanylidene]cyanamide Not in list C10H10F3N3OS CC(C1=CN=C(C=C1)C(F)(F)F)S(=NC#N)(=O)C InChI=1S/C10H10F3N3OS/c1-7(18(2,17)16-6-14)8-3-4-9(15-5-8)10(11,12)13/h3-5,7H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is identical to the substance Sulfoxaflor 946578-00-3 [methyl-oxo-[1-[6(trifluoromethyl)pyridin-3-yl]ethyl]-λ{6}-sulfanylidene]cyanamide Not in list C10H10F3N3OS CC(C1=CN=C(C=C1)C(F)(F)F)S(=NC#N)(=O)C InChI=1S/C10H10F3N3OS/c1-7(18(2,17)16-6-14)8-3-4-9(15-5-8)10(11,12)13/h3-5,7H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is identical to the substance Sulfoxaflor 946578-00-3 [methyl-oxo-[1-[6(trifluoromethyl)pyridin-3-yl]ethyl]-λ{6}-sulfanylidene]cyanamide Not in list C10H10F3N3OS CC(C1=CN=C(C=C1)C(F)(F)F)S(=NC#N)(=O)C InChI=1S/C10H10F3N3OS/c1-7(18(2,17)16-6-14)8-3-4-9(15-5-8)10(11,12)13/h3-5,7H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is identical to the substance Sulfoxaflor 946578-00-3 [methyl-oxo-[1-[6(trifluoromethyl)pyridin-3-yl]ethyl]-λ{6}-sulfanylidene]cyanamide Not in list C10H10F3N3OS CC(C1=CN=C(C=C1)C(F)(F)F)S(=NC#N)(=O)C InChI=1S/C10H10F3N3OS/c1-7(18(2,17)16-6-14)8-3-4-9(15-5-8)10(11,12)13/h3-5,7H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is identical to the substance Sulfoxaflor 946578-00-3 [methyl-oxo-[1-[6(trifluoromethyl)pyridin-3-yl]ethyl]-λ{6}-sulfanylidene]cyanamide Not in list C10H10F3N3OS CC(C1=CN=C(C=C1)C(F)(F)F)S(=NC#N)(=O)C InChI=1S/C10H10F3N3OS/c1-7(18(2,17)16-6-14)8-3-4-9(15-5-8)10(11,12)13/h3-5,7H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is identical to the substance Sulfoxaflor 946578-00-3 [methyl-oxo-[1-[6(trifluoromethyl)pyridin-3-yl]ethyl]-λ{6}-sulfanylidene]cyanamide Not in list C10H10F3N3OS CC(C1=CN=C(C=C1)C(F)(F)F)S(=NC#N)(=O)C InChI=1S/C10H10F3N3OS/c1-7(18(2,17)16-6-14)8-3-4-9(15-5-8)10(11,12)13/h3-5,7H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is identical to the substance Sulfoxaflor 946578-00-3 [methyl-oxo-[1-[6(trifluoromethyl)pyridin-3-yl]ethyl]-λ{6}-sulfanylidene]cyanamide Not in list C10H10F3N3OS CC(C1=CN=C(C=C1)C(F)(F)F)S(=NC#N)(=O)C InChI=1S/C10H10F3N3OS/c1-7(18(2,17)16-6-14)8-3-4-9(15-5-8)10(11,12)13/h3-5,7H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Rat (as animal) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is identical to the substance Sulfoxaflor 946578-00-3 [methyl-oxo-[1-[6(trifluoromethyl)pyridin-3-yl]ethyl]-λ{6}-sulfanylidene]cyanamide Not in list C10H10F3N3OS CC(C1=CN=C(C=C1)C(F)(F)F)S(=NC#N)(=O)C InChI=1S/C10H10F3N3OS/c1-7(18(2,17)16-6-14)8-3-4-9(15-5-8)10(11,12)13/h3-5,7H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Rat (as animal) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is identical to the substance Sulfoxaflor 946578-00-3 [methyl-oxo-[1-[6(trifluoromethyl)pyridin-3-yl]ethyl]-λ{6}-sulfanylidene]cyanamide Not in list C10H10F3N3OS CC(C1=CN=C(C=C1)C(F)(F)F)S(=NC#N)(=O)C InChI=1S/C10H10F3N3OS/c1-7(18(2,17)16-6-14)8-3-4-9(15-5-8)10(11,12)13/h3-5,7H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is identical to the substance Sulfoxaflor 946578-00-3 [methyl-oxo-[1-[6(trifluoromethyl)pyridin-3-yl]ethyl]-λ{6}-sulfanylidene]cyanamide Not in list C10H10F3N3OS CC(C1=CN=C(C=C1)C(F)(F)F)S(=NC#N)(=O)C InChI=1S/C10H10F3N3OS/c1-7(18(2,17)16-6-14)8-3-4-9(15-5-8)10(11,12)13/h3-5,7H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is identical to the substance Sulfoxaflor 946578-00-3 [methyl-oxo-[1-[6(trifluoromethyl)pyridin-3-yl]ethyl]-λ{6}-sulfanylidene]cyanamide Not in list C10H10F3N3OS CC(C1=CN=C(C=C1)C(F)(F)F)S(=NC#N)(=O)C InChI=1S/C10H10F3N3OS/c1-7(18(2,17)16-6-14)8-3-4-9(15-5-8)10(11,12)13/h3-5,7H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 12 Male/Female oral: gavage 24.0000000000 h yes not applicable Negative no evidence RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance 1-[methyl(oxido){(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethyl}-(RS)λ6-sulfanylidene]urea 1-[methyl(oxido){(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethyl}-(RS)λ6-sulfanylidene]urea Not in list C10H12F3N3O2S FC(F)(F)c1ccc(cn1)C(C)S(C)(=O)=NC(N)=O InChI=1/C10H12F3N3O2S/c1-6(19(2,18)16-9(14)17)7-3-4-8(15-5-7)10(11,12)13/h3-6H,1-2H3,(H2,14,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance 1-[methyl(oxido){(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethyl}-(RS)λ6-sulfanylidene]urea 1-[methyl(oxido){(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethyl}-(RS)λ6-sulfanylidene]urea Not in list C10H12F3N3O2S FC(F)(F)c1ccc(cn1)C(C)S(C)(=O)=NC(N)=O InChI=1/C10H12F3N3O2S/c1-6(19(2,18)16-9(14)17)7-3-4-8(15-5-7)10(11,12)13/h3-6H,1-2H3,(H2,14,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance 1-[methyl(oxido){(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethyl}-(RS)λ6-sulfanylidene]urea 1-[methyl(oxido){(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethyl}-(RS)λ6-sulfanylidene]urea Not in list C10H12F3N3O2S FC(F)(F)c1ccc(cn1)C(C)S(C)(=O)=NC(N)=O InChI=1/C10H12F3N3O2S/c1-6(19(2,18)16-9(14)17)7-3-4-8(15-5-7)10(11,12)13/h3-6H,1-2H3,(H2,14,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance 1-[methyl(oxido){(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethyl}-(RS)λ6-sulfanylidene]urea 1-[methyl(oxido){(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethyl}-(RS)λ6-sulfanylidene]urea Not in list C10H12F3N3O2S FC(F)(F)c1ccc(cn1)C(C)S(C)(=O)=NC(N)=O InChI=1/C10H12F3N3O2S/c1-6(19(2,18)16-9(14)17)7-3-4-8(15-5-7)10(11,12)13/h3-6H,1-2H3,(H2,14,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance 1-[methyl(oxido){(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethyl}-(RS)λ6-sulfanylidene]urea 1-[methyl(oxido){(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethyl}-(RS)λ6-sulfanylidene]urea Not in list C10H12F3N3O2S FC(F)(F)c1ccc(cn1)C(C)S(C)(=O)=NC(N)=O InChI=1/C10H12F3N3O2S/c1-6(19(2,18)16-9(14)17)7-3-4-8(15-5-7)10(11,12)13/h3-6H,1-2H3,(H2,14,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance 1-[methyl(oxido){(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethyl}-(RS)λ6-sulfanylidene]urea 1-[methyl(oxido){(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethyl}-(RS)λ6-sulfanylidene]urea Not in list C10H12F3N3O2S FC(F)(F)c1ccc(cn1)C(C)S(C)(=O)=NC(N)=O InChI=1/C10H12F3N3O2S/c1-6(19(2,18)16-9(14)17)7-3-4-8(15-5-7)10(11,12)13/h3-6H,1-2H3,(H2,14,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance 1-[methyl(oxido){(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethyl}-(RS)λ6-sulfanylidene]urea 1-[methyl(oxido){(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethyl}-(RS)λ6-sulfanylidene]urea Not in list C10H12F3N3O2S FC(F)(F)c1ccc(cn1)C(C)S(C)(=O)=NC(N)=O InChI=1/C10H12F3N3O2S/c1-6(19(2,18)16-9(14)17)7-3-4-8(15-5-7)10(11,12)13/h3-6H,1-2H3,(H2,14,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance 1-[methyl(oxido){(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethyl}-(RS)λ6-sulfanylidene]urea 1-[methyl(oxido){(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethyl}-(RS)λ6-sulfanylidene]urea Not in list C10H12F3N3O2S FC(F)(F)c1ccc(cn1)C(C)S(C)(=O)=NC(N)=O InChI=1/C10H12F3N3O2S/c1-6(19(2,18)16-9(14)17)7-3-4-8(15-5-7)10(11,12)13/h3-6H,1-2H3,(H2,14,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance 1-[methyl(oxido){(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethyl}-(RS)λ6-sulfanylidene]urea 1-[methyl(oxido){(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethyl}-(RS)λ6-sulfanylidene]urea Not in list C10H12F3N3O2S FC(F)(F)c1ccc(cn1)C(C)S(C)(=O)=NC(N)=O InChI=1/C10H12F3N3O2S/c1-6(19(2,18)16-9(14)17)7-3-4-8(15-5-7)10(11,12)13/h3-6H,1-2H3,(H2,14,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance 1-[methyl(oxido){(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethyl}-(RS)λ6-sulfanylidene]urea 1-[methyl(oxido){(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethyl}-(RS)λ6-sulfanylidene]urea Not in list C10H12F3N3O2S FC(F)(F)c1ccc(cn1)C(C)S(C)(=O)=NC(N)=O InChI=1/C10H12F3N3O2S/c1-6(19(2,18)16-9(14)17)7-3-4-8(15-5-7)10(11,12)13/h3-6H,1-2H3,(H2,14,17) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance 1-[methyl(oxido){(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethyl}-(RS)λ6-sulfanylidene]urea 1-[methyl(oxido){(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethyl}-(RS)λ6-sulfanylidene]urea Not in list C10H12F3N3O2S FC(F)(F)c1ccc(cn1)C(C)S(C)(=O)=NC(N)=O InChI=1/C10H12F3N3O2S/c1-6(19(2,18)16-9(14)17)7-3-4-8(15-5-7)10(11,12)13/h3-6H,1-2H3,(H2,14,17) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Rat (as animal) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance 1-[methyl(oxido){(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethyl}-(RS)λ6-sulfanylidene]urea 1-[methyl(oxido){(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethyl}-(RS)λ6-sulfanylidene]urea Not in list C10H12F3N3O2S FC(F)(F)c1ccc(cn1)C(C)S(C)(=O)=NC(N)=O InChI=1/C10H12F3N3O2S/c1-6(19(2,18)16-9(14)17)7-3-4-8(15-5-7)10(11,12)13/h3-6H,1-2H3,(H2,14,17) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Rat (as animal) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance 1-[methyl(oxido){(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethyl}-(RS)λ6-sulfanylidene]urea 1-[methyl(oxido){(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethyl}-(RS)λ6-sulfanylidene]urea Not in list C10H12F3N3O2S FC(F)(F)c1ccc(cn1)C(C)S(C)(=O)=NC(N)=O InChI=1/C10H12F3N3O2S/c1-6(19(2,18)16-9(14)17)7-3-4-8(15-5-7)10(11,12)13/h3-6H,1-2H3,(H2,14,17) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance 1-[methyl(oxido){(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethyl}-(RS)λ6-sulfanylidene]urea 1-[methyl(oxido){(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethyl}-(RS)λ6-sulfanylidene]urea Not in list C10H12F3N3O2S FC(F)(F)c1ccc(cn1)C(C)S(C)(=O)=NC(N)=O InChI=1/C10H12F3N3O2S/c1-6(19(2,18)16-9(14)17)7-3-4-8(15-5-7)10(11,12)13/h3-6H,1-2H3,(H2,14,17) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance (1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethanol (1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethanol Not in list C8H8F3NO FC(F)(F)c1ccc(cn1)C(C)O InChI=1/C8H8F3NO/c1-5(13)6-2-3-7(12-4-6)8(9,10)11/h2-5,13H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance (1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethanol (1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethanol Not in list C8H8F3NO FC(F)(F)c1ccc(cn1)C(C)O InChI=1/C8H8F3NO/c1-5(13)6-2-3-7(12-4-6)8(9,10)11/h2-5,13H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance (1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethanol (1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethanol Not in list C8H8F3NO FC(F)(F)c1ccc(cn1)C(C)O InChI=1/C8H8F3NO/c1-5(13)6-2-3-7(12-4-6)8(9,10)11/h2-5,13H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance (1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethanol (1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethanol Not in list C8H8F3NO FC(F)(F)c1ccc(cn1)C(C)O InChI=1/C8H8F3NO/c1-5(13)6-2-3-7(12-4-6)8(9,10)11/h2-5,13H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance (1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethanol (1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethanol Not in list C8H8F3NO FC(F)(F)c1ccc(cn1)C(C)O InChI=1/C8H8F3NO/c1-5(13)6-2-3-7(12-4-6)8(9,10)11/h2-5,13H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance (1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethanol (1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethanol Not in list C8H8F3NO FC(F)(F)c1ccc(cn1)C(C)O InChI=1/C8H8F3NO/c1-5(13)6-2-3-7(12-4-6)8(9,10)11/h2-5,13H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance (1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethanol (1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethanol Not in list C8H8F3NO FC(F)(F)c1ccc(cn1)C(C)O InChI=1/C8H8F3NO/c1-5(13)6-2-3-7(12-4-6)8(9,10)11/h2-5,13H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance (1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethanol (1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethanol Not in list C8H8F3NO FC(F)(F)c1ccc(cn1)C(C)O InChI=1/C8H8F3NO/c1-5(13)6-2-3-7(12-4-6)8(9,10)11/h2-5,13H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance (1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethanol (1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethanol Not in list C8H8F3NO FC(F)(F)c1ccc(cn1)C(C)O InChI=1/C8H8F3NO/c1-5(13)6-2-3-7(12-4-6)8(9,10)11/h2-5,13H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance (1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethanol (1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethanol Not in list C8H8F3NO FC(F)(F)c1ccc(cn1)C(C)O InChI=1/C8H8F3NO/c1-5(13)6-2-3-7(12-4-6)8(9,10)11/h2-5,13H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance (1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethanol (1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethanol Not in list C8H8F3NO FC(F)(F)c1ccc(cn1)C(C)O InChI=1/C8H8F3NO/c1-5(13)6-2-3-7(12-4-6)8(9,10)11/h2-5,13H,1H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Rat (as animal) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance (1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethanol (1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethanol Not in list C8H8F3NO FC(F)(F)c1ccc(cn1)C(C)O InChI=1/C8H8F3NO/c1-5(13)6-2-3-7(12-4-6)8(9,10)11/h2-5,13H,1H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Rat (as animal) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance (1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethanol (1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethanol Not in list C8H8F3NO FC(F)(F)c1ccc(cn1)C(C)O InChI=1/C8H8F3NO/c1-5(13)6-2-3-7(12-4-6)8(9,10)11/h2-5,13H,1H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance (1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethanol (1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethanol Not in list C8H8F3NO FC(F)(F)c1ccc(cn1)C(C)O InChI=1/C8H8F3NO/c1-5(13)6-2-3-7(12-4-6)8(9,10)11/h2-5,13H,1H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance 5-ethyl-2-(trifluoromethyl)pyridine 5-ethyl-2-(trifluoromethyl)pyridine Not in list C8H8F3N FC(F)(F)c1ccc(CC)cn1 InChI=1/C8H8F3N/c1-2-6-3-4-7(12-5-6)8(9,10)11/h3-5H,2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance 5-ethyl-2-(trifluoromethyl)pyridine 5-ethyl-2-(trifluoromethyl)pyridine Not in list C8H8F3N FC(F)(F)c1ccc(CC)cn1 InChI=1/C8H8F3N/c1-2-6-3-4-7(12-5-6)8(9,10)11/h3-5H,2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance 5-ethyl-2-(trifluoromethyl)pyridine 5-ethyl-2-(trifluoromethyl)pyridine Not in list C8H8F3N FC(F)(F)c1ccc(CC)cn1 InChI=1/C8H8F3N/c1-2-6-3-4-7(12-5-6)8(9,10)11/h3-5H,2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance 5-ethyl-2-(trifluoromethyl)pyridine 5-ethyl-2-(trifluoromethyl)pyridine Not in list C8H8F3N FC(F)(F)c1ccc(CC)cn1 InChI=1/C8H8F3N/c1-2-6-3-4-7(12-5-6)8(9,10)11/h3-5H,2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance 5-ethyl-2-(trifluoromethyl)pyridine 5-ethyl-2-(trifluoromethyl)pyridine Not in list C8H8F3N FC(F)(F)c1ccc(CC)cn1 InChI=1/C8H8F3N/c1-2-6-3-4-7(12-5-6)8(9,10)11/h3-5H,2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance 5-ethyl-2-(trifluoromethyl)pyridine 5-ethyl-2-(trifluoromethyl)pyridine Not in list C8H8F3N FC(F)(F)c1ccc(CC)cn1 InChI=1/C8H8F3N/c1-2-6-3-4-7(12-5-6)8(9,10)11/h3-5H,2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance 5-ethyl-2-(trifluoromethyl)pyridine 5-ethyl-2-(trifluoromethyl)pyridine Not in list C8H8F3N FC(F)(F)c1ccc(CC)cn1 InChI=1/C8H8F3N/c1-2-6-3-4-7(12-5-6)8(9,10)11/h3-5H,2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance 5-ethyl-2-(trifluoromethyl)pyridine 5-ethyl-2-(trifluoromethyl)pyridine Not in list C8H8F3N FC(F)(F)c1ccc(CC)cn1 InChI=1/C8H8F3N/c1-2-6-3-4-7(12-5-6)8(9,10)11/h3-5H,2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance 5-ethyl-2-(trifluoromethyl)pyridine 5-ethyl-2-(trifluoromethyl)pyridine Not in list C8H8F3N FC(F)(F)c1ccc(CC)cn1 InChI=1/C8H8F3N/c1-2-6-3-4-7(12-5-6)8(9,10)11/h3-5H,2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance 5-ethyl-2-(trifluoromethyl)pyridine 5-ethyl-2-(trifluoromethyl)pyridine Not in list C8H8F3N FC(F)(F)c1ccc(CC)cn1 InChI=1/C8H8F3N/c1-2-6-3-4-7(12-5-6)8(9,10)11/h3-5H,2H2,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance 5-[(1RS)-1-(S-methylsulfonimidoyl)ethyl]-2-(trifluoromethyl)pyridine 5-[(1RS)-1-(S-methylsulfonimidoyl)ethyl]-2-(trifluoromethyl)pyridine Not in list C9H11F3N2OS FC(F)(F)c1ccc(cn1)C(C)S(C)(=N)=O InChI=1/C9H11F3N2OS/c1-6(16(2,13)15)7-3-4-8(14-5-7)9(10,11)12/h3-6,13H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance 5-[(1RS)-1-(S-methylsulfonimidoyl)ethyl]-2-(trifluoromethyl)pyridine 5-[(1RS)-1-(S-methylsulfonimidoyl)ethyl]-2-(trifluoromethyl)pyridine Not in list C9H11F3N2OS FC(F)(F)c1ccc(cn1)C(C)S(C)(=N)=O InChI=1/C9H11F3N2OS/c1-6(16(2,13)15)7-3-4-8(14-5-7)9(10,11)12/h3-6,13H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance 5-[(1RS)-1-(S-methylsulfonimidoyl)ethyl]-2-(trifluoromethyl)pyridine 5-[(1RS)-1-(S-methylsulfonimidoyl)ethyl]-2-(trifluoromethyl)pyridine Not in list C9H11F3N2OS FC(F)(F)c1ccc(cn1)C(C)S(C)(=N)=O InChI=1/C9H11F3N2OS/c1-6(16(2,13)15)7-3-4-8(14-5-7)9(10,11)12/h3-6,13H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance 5-[(1RS)-1-(S-methylsulfonimidoyl)ethyl]-2-(trifluoromethyl)pyridine 5-[(1RS)-1-(S-methylsulfonimidoyl)ethyl]-2-(trifluoromethyl)pyridine Not in list C9H11F3N2OS FC(F)(F)c1ccc(cn1)C(C)S(C)(=N)=O InChI=1/C9H11F3N2OS/c1-6(16(2,13)15)7-3-4-8(14-5-7)9(10,11)12/h3-6,13H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance 5-[(1RS)-1-(S-methylsulfonimidoyl)ethyl]-2-(trifluoromethyl)pyridine 5-[(1RS)-1-(S-methylsulfonimidoyl)ethyl]-2-(trifluoromethyl)pyridine Not in list C9H11F3N2OS FC(F)(F)c1ccc(cn1)C(C)S(C)(=N)=O InChI=1/C9H11F3N2OS/c1-6(16(2,13)15)7-3-4-8(14-5-7)9(10,11)12/h3-6,13H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance 5-[(1RS)-1-(S-methylsulfonimidoyl)ethyl]-2-(trifluoromethyl)pyridine 5-[(1RS)-1-(S-methylsulfonimidoyl)ethyl]-2-(trifluoromethyl)pyridine Not in list C9H11F3N2OS FC(F)(F)c1ccc(cn1)C(C)S(C)(=N)=O InChI=1/C9H11F3N2OS/c1-6(16(2,13)15)7-3-4-8(14-5-7)9(10,11)12/h3-6,13H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance 5-[(1RS)-1-(S-methylsulfonimidoyl)ethyl]-2-(trifluoromethyl)pyridine 5-[(1RS)-1-(S-methylsulfonimidoyl)ethyl]-2-(trifluoromethyl)pyridine Not in list C9H11F3N2OS FC(F)(F)c1ccc(cn1)C(C)S(C)(=N)=O InChI=1/C9H11F3N2OS/c1-6(16(2,13)15)7-3-4-8(14-5-7)9(10,11)12/h3-6,13H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance 5-[(1RS)-1-(S-methylsulfonimidoyl)ethyl]-2-(trifluoromethyl)pyridine 5-[(1RS)-1-(S-methylsulfonimidoyl)ethyl]-2-(trifluoromethyl)pyridine Not in list C9H11F3N2OS FC(F)(F)c1ccc(cn1)C(C)S(C)(=N)=O InChI=1/C9H11F3N2OS/c1-6(16(2,13)15)7-3-4-8(14-5-7)9(10,11)12/h3-6,13H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance 5-[(1RS)-1-(S-methylsulfonimidoyl)ethyl]-2-(trifluoromethyl)pyridine 5-[(1RS)-1-(S-methylsulfonimidoyl)ethyl]-2-(trifluoromethyl)pyridine Not in list C9H11F3N2OS FC(F)(F)c1ccc(cn1)C(C)S(C)(=N)=O InChI=1/C9H11F3N2OS/c1-6(16(2,13)15)7-3-4-8(14-5-7)9(10,11)12/h3-6,13H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance 5-[(1RS)-1-(S-methylsulfonimidoyl)ethyl]-2-(trifluoromethyl)pyridine 5-[(1RS)-1-(S-methylsulfonimidoyl)ethyl]-2-(trifluoromethyl)pyridine Not in list C9H11F3N2OS FC(F)(F)c1ccc(cn1)C(C)S(C)(=N)=O InChI=1/C9H11F3N2OS/c1-6(16(2,13)15)7-3-4-8(14-5-7)9(10,11)12/h3-6,13H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance 5-[(1RS)-1-(S-methylsulfonimidoyl)ethyl]-2-(trifluoromethyl)pyridine 5-[(1RS)-1-(S-methylsulfonimidoyl)ethyl]-2-(trifluoromethyl)pyridine Not in list C9H11F3N2OS FC(F)(F)c1ccc(cn1)C(C)S(C)(=N)=O InChI=1/C9H11F3N2OS/c1-6(16(2,13)15)7-3-4-8(14-5-7)9(10,11)12/h3-6,13H,1-2H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Rat (as animal) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance 5-[(1RS)-1-(S-methylsulfonimidoyl)ethyl]-2-(trifluoromethyl)pyridine 5-[(1RS)-1-(S-methylsulfonimidoyl)ethyl]-2-(trifluoromethyl)pyridine Not in list C9H11F3N2OS FC(F)(F)c1ccc(cn1)C(C)S(C)(=N)=O InChI=1/C9H11F3N2OS/c1-6(16(2,13)15)7-3-4-8(14-5-7)9(10,11)12/h3-6,13H,1-2H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Rat (as animal) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance 5-[(1RS)-1-(S-methylsulfonimidoyl)ethyl]-2-(trifluoromethyl)pyridine 5-[(1RS)-1-(S-methylsulfonimidoyl)ethyl]-2-(trifluoromethyl)pyridine Not in list C9H11F3N2OS FC(F)(F)c1ccc(cn1)C(C)S(C)(=N)=O InChI=1/C9H11F3N2OS/c1-6(16(2,13)15)7-3-4-8(14-5-7)9(10,11)12/h3-6,13H,1-2H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance 5-[(1RS)-1-(S-methylsulfonimidoyl)ethyl]-2-(trifluoromethyl)pyridine 5-[(1RS)-1-(S-methylsulfonimidoyl)ethyl]-2-(trifluoromethyl)pyridine Not in list C9H11F3N2OS FC(F)(F)c1ccc(cn1)C(C)S(C)(=N)=O InChI=1/C9H11F3N2OS/c1-6(16(2,13)15)7-3-4-8(14-5-7)9(10,11)12/h3-6,13H,1-2H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance 5-[(1RS)-1-(methylsulfonyl)ethyl]-2-(trifluoromethyl)pyridine 5-[(1RS)-1-(methylsulfonyl)ethyl]-2-(trifluoromethyl)pyridine Not in list C9H10F3NO2S FC(F)(F)c1ccc(cn1)C(C)S(C)(=O)=O InChI=1/C9H10F3NO2S/c1-6(16(2,14)15)7-3-4-8(13-5-7)9(10,11)12/h3-6H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance 5-[(1RS)-1-(methylsulfonyl)ethyl]-2-(trifluoromethyl)pyridine 5-[(1RS)-1-(methylsulfonyl)ethyl]-2-(trifluoromethyl)pyridine Not in list C9H10F3NO2S FC(F)(F)c1ccc(cn1)C(C)S(C)(=O)=O InChI=1/C9H10F3NO2S/c1-6(16(2,14)15)7-3-4-8(13-5-7)9(10,11)12/h3-6H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance 5-[(1RS)-1-(methylsulfonyl)ethyl]-2-(trifluoromethyl)pyridine 5-[(1RS)-1-(methylsulfonyl)ethyl]-2-(trifluoromethyl)pyridine Not in list C9H10F3NO2S FC(F)(F)c1ccc(cn1)C(C)S(C)(=O)=O InChI=1/C9H10F3NO2S/c1-6(16(2,14)15)7-3-4-8(13-5-7)9(10,11)12/h3-6H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance 5-[(1RS)-1-(methylsulfonyl)ethyl]-2-(trifluoromethyl)pyridine 5-[(1RS)-1-(methylsulfonyl)ethyl]-2-(trifluoromethyl)pyridine Not in list C9H10F3NO2S FC(F)(F)c1ccc(cn1)C(C)S(C)(=O)=O InChI=1/C9H10F3NO2S/c1-6(16(2,14)15)7-3-4-8(13-5-7)9(10,11)12/h3-6H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance 5-[(1RS)-1-(methylsulfonyl)ethyl]-2-(trifluoromethyl)pyridine 5-[(1RS)-1-(methylsulfonyl)ethyl]-2-(trifluoromethyl)pyridine Not in list C9H10F3NO2S FC(F)(F)c1ccc(cn1)C(C)S(C)(=O)=O InChI=1/C9H10F3NO2S/c1-6(16(2,14)15)7-3-4-8(13-5-7)9(10,11)12/h3-6H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance 5-[(1RS)-1-(methylsulfonyl)ethyl]-2-(trifluoromethyl)pyridine 5-[(1RS)-1-(methylsulfonyl)ethyl]-2-(trifluoromethyl)pyridine Not in list C9H10F3NO2S FC(F)(F)c1ccc(cn1)C(C)S(C)(=O)=O InChI=1/C9H10F3NO2S/c1-6(16(2,14)15)7-3-4-8(13-5-7)9(10,11)12/h3-6H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance 5-[(1RS)-1-(methylsulfonyl)ethyl]-2-(trifluoromethyl)pyridine 5-[(1RS)-1-(methylsulfonyl)ethyl]-2-(trifluoromethyl)pyridine Not in list C9H10F3NO2S FC(F)(F)c1ccc(cn1)C(C)S(C)(=O)=O InChI=1/C9H10F3NO2S/c1-6(16(2,14)15)7-3-4-8(13-5-7)9(10,11)12/h3-6H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance 5-[(1RS)-1-(methylsulfonyl)ethyl]-2-(trifluoromethyl)pyridine 5-[(1RS)-1-(methylsulfonyl)ethyl]-2-(trifluoromethyl)pyridine Not in list C9H10F3NO2S FC(F)(F)c1ccc(cn1)C(C)S(C)(=O)=O InChI=1/C9H10F3NO2S/c1-6(16(2,14)15)7-3-4-8(13-5-7)9(10,11)12/h3-6H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance 5-[(1RS)-1-(methylsulfonyl)ethyl]-2-(trifluoromethyl)pyridine 5-[(1RS)-1-(methylsulfonyl)ethyl]-2-(trifluoromethyl)pyridine Not in list C9H10F3NO2S FC(F)(F)c1ccc(cn1)C(C)S(C)(=O)=O InChI=1/C9H10F3NO2S/c1-6(16(2,14)15)7-3-4-8(13-5-7)9(10,11)12/h3-6H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance 5-[(1RS)-1-(methylsulfonyl)ethyl]-2-(trifluoromethyl)pyridine 5-[(1RS)-1-(methylsulfonyl)ethyl]-2-(trifluoromethyl)pyridine Not in list C9H10F3NO2S FC(F)(F)c1ccc(cn1)C(C)S(C)(=O)=O InChI=1/C9H10F3NO2S/c1-6(16(2,14)15)7-3-4-8(13-5-7)9(10,11)12/h3-6H,1-2H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance 5-[(1RS)-1-(methylsulfonyl)ethyl]-2-(trifluoromethyl)pyridine 5-[(1RS)-1-(methylsulfonyl)ethyl]-2-(trifluoromethyl)pyridine Not in list C9H10F3NO2S FC(F)(F)c1ccc(cn1)C(C)S(C)(=O)=O InChI=1/C9H10F3NO2S/c1-6(16(2,14)15)7-3-4-8(13-5-7)9(10,11)12/h3-6H,1-2H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Rat (as animal) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance 5-[(1RS)-1-(methylsulfonyl)ethyl]-2-(trifluoromethyl)pyridine 5-[(1RS)-1-(methylsulfonyl)ethyl]-2-(trifluoromethyl)pyridine Not in list C9H10F3NO2S FC(F)(F)c1ccc(cn1)C(C)S(C)(=O)=O InChI=1/C9H10F3NO2S/c1-6(16(2,14)15)7-3-4-8(13-5-7)9(10,11)12/h3-6H,1-2H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Rat (as animal) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance 5-[(1RS)-1-(methylsulfonyl)ethyl]-2-(trifluoromethyl)pyridine 5-[(1RS)-1-(methylsulfonyl)ethyl]-2-(trifluoromethyl)pyridine Not in list C9H10F3NO2S FC(F)(F)c1ccc(cn1)C(C)S(C)(=O)=O InChI=1/C9H10F3NO2S/c1-6(16(2,14)15)7-3-4-8(13-5-7)9(10,11)12/h3-6H,1-2H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Sulfoxaflor 946578-00-3 single chemical entity Component is a metabolite of the substance 5-[(1RS)-1-(methylsulfonyl)ethyl]-2-(trifluoromethyl)pyridine 5-[(1RS)-1-(methylsulfonyl)ethyl]-2-(trifluoromethyl)pyridine Not in list C9H10F3NO2S FC(F)(F)c1ccc(cn1)C(C)S(C)(=O)=O InChI=1/C9H10F3NO2S/c1-6(16(2,14)15)7-3-4-8(13-5-7)9(10,11)12/h3-6H,1-2H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Ireland Sulfoxaflor 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor 21May2014 2014 doi:10.2903/j.efsa.2014.3692
+Flurochloridone 262-661-3 61213-25-0 single chemical entity Component is identical to the substance Flurochloridone 262-661-3 61213-25-0 3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one Flurochloridone C12H10Cl2F3NO C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Spain Flurochloridone 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a 14Dec2010 2010 doi:10.2903/j.efsa.2010.1869
+Flurochloridone 262-661-3 61213-25-0 single chemical entity Component is identical to the substance Flurochloridone 262-661-3 61213-25-0 3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one Flurochloridone C12H10Cl2F3NO C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Saccharomyces cerevisiae (as organism) D4 Not reported yes, concurrent vehicle without Negative RMS: Spain Flurochloridone 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a 14Dec2010 2010 doi:10.2903/j.efsa.2010.1869
+Flurochloridone 262-661-3 61213-25-0 single chemical entity Component is identical to the substance Flurochloridone 262-661-3 61213-25-0 3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one Flurochloridone C12H10Cl2F3NO C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Spain Flurochloridone 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a 14Dec2010 2010 doi:10.2903/j.efsa.2010.1869
+Flurochloridone 262-661-3 61213-25-0 single chemical entity Component is identical to the substance Flurochloridone 262-661-3 61213-25-0 3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one Flurochloridone C12H10Cl2F3NO C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Spain Flurochloridone 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a 14Dec2010 2010 doi:10.2903/j.efsa.2010.1869
+Flurochloridone 262-661-3 61213-25-0 single chemical entity Component is identical to the substance Flurochloridone 262-661-3 61213-25-0 3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one Flurochloridone C12H10Cl2F3NO C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Spain Flurochloridone 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a 14Dec2010 2010 doi:10.2903/j.efsa.2010.1869
+Flurochloridone 262-661-3 61213-25-0 single chemical entity Component is identical to the substance Flurochloridone 262-661-3 61213-25-0 3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one Flurochloridone C12H10Cl2F3NO C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Spain Flurochloridone 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a 14Dec2010 2010 doi:10.2903/j.efsa.2010.1869
+Flurochloridone 262-661-3 61213-25-0 single chemical entity Component is identical to the substance Flurochloridone 262-661-3 61213-25-0 3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one Flurochloridone C12H10Cl2F3NO C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Spain Flurochloridone 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a 14Dec2010 2010 doi:10.2903/j.efsa.2010.1869
+Flurochloridone 262-661-3 61213-25-0 single chemical entity Component is identical to the substance Flurochloridone 262-661-3 61213-25-0 3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one Flurochloridone C12H10Cl2F3NO C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Spain Flurochloridone 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a 14Dec2010 2010 doi:10.2903/j.efsa.2010.1869
+Flurochloridone 262-661-3 61213-25-0 single chemical entity Component is identical to the substance Flurochloridone 262-661-3 61213-25-0 3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one Flurochloridone C12H10Cl2F3NO C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Spain Flurochloridone 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a 14Dec2010 2010 doi:10.2903/j.efsa.2010.1869
+Flurochloridone 262-661-3 61213-25-0 single chemical entity Component is identical to the substance Flurochloridone 262-661-3 61213-25-0 3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one Flurochloridone C12H10Cl2F3NO C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Spain Flurochloridone 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a 14Dec2010 2010 doi:10.2903/j.efsa.2010.1869
+Flurochloridone 262-661-3 61213-25-0 single chemical entity Component is identical to the substance Flurochloridone 262-661-3 61213-25-0 3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one Flurochloridone C12H10Cl2F3NO C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Saccharomyces cerevisiae (as organism) D4 Not reported yes, concurrent vehicle with Negative RMS: Spain Flurochloridone 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a 14Dec2010 2010 doi:10.2903/j.efsa.2010.1869
+Flurochloridone 262-661-3 61213-25-0 single chemical entity Component is identical to the substance Flurochloridone 262-661-3 61213-25-0 3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one Flurochloridone C12H10Cl2F3NO C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Spain Flurochloridone 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a 14Dec2010 2010 doi:10.2903/j.efsa.2010.1869
+Flurochloridone 262-661-3 61213-25-0 single chemical entity Component is identical to the substance Flurochloridone 262-661-3 61213-25-0 3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one Flurochloridone C12H10Cl2F3NO C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Saccharomyces cerevisiae (as organism) D4 Not reported yes, concurrent vehicle without Negative RMS: Spain Flurochloridone 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a 14Dec2010 2010 doi:10.2903/j.efsa.2010.1869
+Flurochloridone 262-661-3 61213-25-0 single chemical entity Component is identical to the substance Flurochloridone 262-661-3 61213-25-0 3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one Flurochloridone C12H10Cl2F3NO C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Spain Flurochloridone 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a 14Dec2010 2010 doi:10.2903/j.efsa.2010.1869
+Flurochloridone 262-661-3 61213-25-0 single chemical entity Component is identical to the substance Flurochloridone 262-661-3 61213-25-0 3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one Flurochloridone C12H10Cl2F3NO C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Spain Flurochloridone 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a 14Dec2010 2010 doi:10.2903/j.efsa.2010.1869
+Flurochloridone 262-661-3 61213-25-0 single chemical entity Component is identical to the substance Flurochloridone 262-661-3 61213-25-0 3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one Flurochloridone C12H10Cl2F3NO C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Saccharomyces cerevisiae (as organism) D4 Not reported yes, concurrent vehicle with Negative RMS: Spain Flurochloridone 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a 14Dec2010 2010 doi:10.2903/j.efsa.2010.1869
+Flurochloridone 262-661-3 61213-25-0 single chemical entity Component is identical to the substance Flurochloridone 262-661-3 61213-25-0 3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one Flurochloridone C12H10Cl2F3NO C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Spain Flurochloridone 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a 14Dec2010 2010 doi:10.2903/j.efsa.2010.1869
+Flurochloridone 262-661-3 61213-25-0 single chemical entity Component is identical to the substance Flurochloridone 262-661-3 61213-25-0 3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one Flurochloridone C12H10Cl2F3NO C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Spain Flurochloridone 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a 14Dec2010 2010 doi:10.2903/j.efsa.2010.1869
+Flurochloridone 262-661-3 61213-25-0 single chemical entity Component is identical to the substance Flurochloridone 262-661-3 61213-25-0 3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one Flurochloridone C12H10Cl2F3NO C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Spain Flurochloridone 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a 14Dec2010 2010 doi:10.2903/j.efsa.2010.1869
+Flurochloridone 262-661-3 61213-25-0 single chemical entity Component is identical to the substance Flurochloridone 262-661-3 61213-25-0 3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one Flurochloridone C12H10Cl2F3NO C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Spain Flurochloridone 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a 14Dec2010 2010 doi:10.2903/j.efsa.2010.1869
+Flurochloridone 262-661-3 61213-25-0 single chemical entity Component is identical to the substance Flurochloridone 262-661-3 61213-25-0 3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one Flurochloridone C12H10Cl2F3NO C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Spain Flurochloridone 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a 14Dec2010 2010 doi:10.2903/j.efsa.2010.1869
+Flurochloridone 262-661-3 61213-25-0 single chemical entity Component is identical to the substance Flurochloridone 262-661-3 61213-25-0 3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one Flurochloridone C12H10Cl2F3NO C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Spain Flurochloridone 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a 14Dec2010 2010 doi:10.2903/j.efsa.2010.1869
+Flurochloridone 262-661-3 61213-25-0 single chemical entity Component is identical to the substance Flurochloridone 262-661-3 61213-25-0 3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one Flurochloridone C12H10Cl2F3NO C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Spain Flurochloridone 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a 14Dec2010 2010 doi:10.2903/j.efsa.2010.1869
+Flurochloridone 262-661-3 61213-25-0 single chemical entity Component is identical to the substance Flurochloridone 262-661-3 61213-25-0 3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one Flurochloridone C12H10Cl2F3NO C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Spain Flurochloridone 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a 14Dec2010 2010 doi:10.2903/j.efsa.2010.1869
+Flurochloridone 262-661-3 61213-25-0 single chemical entity Component is identical to the substance Flurochloridone 262-661-3 61213-25-0 3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one Flurochloridone C12H10Cl2F3NO C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Spain Flurochloridone 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a 14Dec2010 2010 doi:10.2903/j.efsa.2010.1869
+Flurochloridone 262-661-3 61213-25-0 single chemical entity Component is identical to the substance Flurochloridone 262-661-3 61213-25-0 3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one Flurochloridone C12H10Cl2F3NO C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Spain Flurochloridone 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a 14Dec2010 2010 doi:10.2903/j.efsa.2010.1869
+Flurochloridone 262-661-3 61213-25-0 single chemical entity Component is identical to the substance Flurochloridone 262-661-3 61213-25-0 3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one Flurochloridone C12H10Cl2F3NO C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Human (as organism) fibroblast Not reported yes, concurrent vehicle without Negative RMS: Spain Flurochloridone 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a 14Dec2010 2010 doi:10.2903/j.efsa.2010.1869
+Flurochloridone 262-661-3 61213-25-0 single chemical entity Component is identical to the substance Flurochloridone 262-661-3 61213-25-0 3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one Flurochloridone C12H10Cl2F3NO C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Human (as organism) fibroblast Not reported yes, concurrent vehicle with Negative RMS: Spain Flurochloridone 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a 14Dec2010 2010 doi:10.2903/j.efsa.2010.1869
+Flurochloridone 262-661-3 61213-25-0 single chemical entity Component is identical to the substance Flurochloridone 262-661-3 61213-25-0 3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one Flurochloridone C12H10Cl2F3NO C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Human (as organism) HeLa cells Not reported yes, concurrent vehicle without Negative RMS: Spain Flurochloridone 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a 14Dec2010 2010 doi:10.2903/j.efsa.2010.1869
+Flurochloridone 262-661-3 61213-25-0 single chemical entity Component is identical to the substance Flurochloridone 262-661-3 61213-25-0 3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one Flurochloridone C12H10Cl2F3NO C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Human (as organism) HeLa cells Not reported yes, concurrent vehicle with Negative RMS: Spain Flurochloridone 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a 14Dec2010 2010 doi:10.2903/j.efsa.2010.1869
+Flurochloridone 262-661-3 61213-25-0 single chemical entity Component is identical to the substance Flurochloridone 262-661-3 61213-25-0 3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one Flurochloridone C12H10Cl2F3NO C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair in vitro mammalian cell transformation assay in vitro No guideline available Not reported Not applicable Acceptable House mouse (as animal) Not reported Not reported yes, concurrent vehicle without Negative RMS: Spain Flurochloridone 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a 14Dec2010 2010 doi:10.2903/j.efsa.2010.1869
+Flurochloridone 262-661-3 61213-25-0 single chemical entity Component is identical to the substance Flurochloridone 262-661-3 61213-25-0 3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one Flurochloridone C12H10Cl2F3NO C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 72.0000000000 h yes not applicable Negative no evidence RMS: Spain Flurochloridone 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a 14Dec2010 2010 doi:10.2903/j.efsa.2010.1869
+Flurochloridone 262-661-3 61213-25-0 single chemical entity Component is identical to the substance Flurochloridone 262-661-3 61213-25-0 3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one Flurochloridone C12H10Cl2F3NO C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 48.0000000000 h yes not applicable Negative no evidence RMS: Spain Flurochloridone 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a 14Dec2010 2010 doi:10.2903/j.efsa.2010.1869
+Flurochloridone 262-661-3 61213-25-0 single chemical entity Component is identical to the substance Flurochloridone 262-661-3 61213-25-0 3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one Flurochloridone C12H10Cl2F3NO C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes not applicable Negative no evidence RMS: Spain Flurochloridone 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a 14Dec2010 2010 doi:10.2903/j.efsa.2010.1869
+Flurochloridone 262-661-3 61213-25-0 single chemical entity Component is identical to the substance Flurochloridone 262-661-3 61213-25-0 3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one Flurochloridone C12H10Cl2F3NO C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Spain Flurochloridone (Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a 14Dec2010 2010 doi:10.2903/j.efsa.2010.1869
+Flurochloridone 262-661-3 61213-25-0 single chemical entity Component is identical to the substance Flurochloridone 262-661-3 61213-25-0 3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one Flurochloridone C12H10Cl2F3NO C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Spain Flurochloridone (Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a 14Dec2010 2010 doi:10.2903/j.efsa.2010.1869
+Flurochloridone 262-661-3 61213-25-0 single chemical entity Component is identical to the substance Flurochloridone 262-661-3 61213-25-0 3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one Flurochloridone C12H10Cl2F3NO C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Spain Flurochloridone (Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a 14Dec2010 2010 doi:10.2903/j.efsa.2010.1869
+Flurochloridone 262-661-3 61213-25-0 single chemical entity Component is identical to the substance Flurochloridone 262-661-3 61213-25-0 3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one Flurochloridone C12H10Cl2F3NO C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Spain Flurochloridone (Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a 14Dec2010 2010 doi:10.2903/j.efsa.2010.1869
+Flurochloridone 262-661-3 61213-25-0 single chemical entity Component is identical to the substance Flurochloridone 262-661-3 61213-25-0 3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one Flurochloridone C12H10Cl2F3NO C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Spain Flurochloridone (Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a 14Dec2010 2010 doi:10.2903/j.efsa.2010.1869
+Flurochloridone 262-661-3 61213-25-0 single chemical entity Component is identical to the substance Flurochloridone 262-661-3 61213-25-0 3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one Flurochloridone C12H10Cl2F3NO C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Spain Flurochloridone (Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a 14Dec2010 2010 doi:10.2903/j.efsa.2010.1869
+Flurochloridone 262-661-3 61213-25-0 single chemical entity Component is identical to the substance Flurochloridone 262-661-3 61213-25-0 3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one Flurochloridone C12H10Cl2F3NO C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Spain Flurochloridone (Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a 14Dec2010 2010 doi:10.2903/j.efsa.2010.1869
+Flurochloridone 262-661-3 61213-25-0 single chemical entity Component is identical to the substance Flurochloridone 262-661-3 61213-25-0 3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one Flurochloridone C12H10Cl2F3NO C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Spain Flurochloridone (Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a 14Dec2010 2010 doi:10.2903/j.efsa.2010.1869
+Flurochloridone 262-661-3 61213-25-0 single chemical entity Component is identical to the substance Flurochloridone 262-661-3 61213-25-0 3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one Flurochloridone C12H10Cl2F3NO C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Spain Flurochloridone (Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a 14Dec2010 2010 doi:10.2903/j.efsa.2010.1869
+Flurochloridone 262-661-3 61213-25-0 single chemical entity Component is identical to the substance Flurochloridone 262-661-3 61213-25-0 3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one Flurochloridone C12H10Cl2F3NO C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Spain Flurochloridone (Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a 14Dec2010 2010 doi:10.2903/j.efsa.2010.1869
+Flurochloridone 262-661-3 61213-25-0 single chemical entity Component is identical to the substance Flurochloridone 262-661-3 61213-25-0 3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one Flurochloridone C12H10Cl2F3NO C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative large colonies RMS: Spain Flurochloridone (Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a 14Dec2010 2010 doi:10.2903/j.efsa.2010.1869
+Flurochloridone 262-661-3 61213-25-0 single chemical entity Component is identical to the substance Flurochloridone 262-661-3 61213-25-0 3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one Flurochloridone C12H10Cl2F3NO C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative large colonies RMS: Spain Flurochloridone (Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a 14Dec2010 2010 doi:10.2903/j.efsa.2010.1869
+Flurochloridone 262-661-3 61213-25-0 single chemical entity Component is identical to the substance Flurochloridone 262-661-3 61213-25-0 3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one Flurochloridone C12H10Cl2F3NO C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative small colonies RMS: Spain Flurochloridone (Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a 14Dec2010 2010 doi:10.2903/j.efsa.2010.1869
+Flurochloridone 262-661-3 61213-25-0 single chemical entity Component is identical to the substance Flurochloridone 262-661-3 61213-25-0 3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one Flurochloridone C12H10Cl2F3NO C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative small colonies RMS: Spain Flurochloridone (Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a 14Dec2010 2010 doi:10.2903/j.efsa.2010.1869
+Flurochloridone 262-661-3 61213-25-0 single chemical entity Component is identical to the substance Flurochloridone 262-661-3 61213-25-0 3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one Flurochloridone C12H10Cl2F3NO C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: Spain Flurochloridone (Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a 14Dec2010 2010 doi:10.2903/j.efsa.2010.1869
+Flurochloridone 262-661-3 61213-25-0 single chemical entity Component is identical to the substance Flurochloridone 262-661-3 61213-25-0 3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one Flurochloridone C12H10Cl2F3NO C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: Spain Flurochloridone (Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a 14Dec2010 2010 doi:10.2903/j.efsa.2010.1869
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Positive no information RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Positive no information RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Positive RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Human (as organism) HeLa cells Not reported yes with Negative RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Human (as organism) HeLa cells Not reported yes without Negative RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 72.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Sprague-Dawley 4 Male oral: gavage 2.0000000000 h yes not applicable Negative RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Sprague-Dawley 4 Male oral: gavage 14.0000000000 h yes not applicable Negative RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration mammalian germ cell cytogenetic assay in vivo According to OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test) No Acceptable House mouse (as animal) ICR 5 Male oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI chromosome aberration mammalian germ cell cytogenetic assay in vivo According to OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test) No Acceptable House mouse (as animal) ICR 5 Male oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported no data with Negative RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported no data with Negative RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) (k12)p3478 Not reported no data with Negative RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro No guideline followed Not reported No data Acceptable Saccharomyces cerevisiae (as organism) D3 Not reported no data without Negative RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) (k12)p3478 Not reported no data without Negative RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported no data without Negative RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported no data without Negative RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro No guideline followed Not reported No data Acceptable Saccharomyces cerevisiae (as organism) D3 Not reported no data with Negative RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported no data without Negative RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported no data with Negative RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported no data without Negative RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported no data with Negative RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Formetanate hydrochloride 245-656-0 23422-53-9 single chemical entity Component is identical to the substance Formetanate hydrochloride 245-656-0 23422-53-9 [3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride Formetanate hydrochloride C11H16ClN3O2 CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Italy Formetanate 2004 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate 13Jun2006 2006 doi:10.2903/j.efsa.2006.69r
+Fuberidazole 223-404-0 3878-19-1 single chemical entity Component is identical to the substance Fuberidazole 223-404-0 3878-19-1 2-(2-furyl)-1H-benzimidazole Fuberidazole C11H8N2O o1cccc1c2nc3ccccc3[nH]2 InChI=1/C11H8N2O/c1-2-5-9-8(4-1)12-11(13-9)10-6-3-7-14-10/h1-7H,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fuberidazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fuberidazole 09Jan2008 2008 doi:10.2903/j.efsa.2008.118r
+Fuberidazole 223-404-0 3878-19-1 single chemical entity Component is identical to the substance Fuberidazole 223-404-0 3878-19-1 2-(2-furyl)-1H-benzimidazole Fuberidazole C11H8N2O o1cccc1c2nc3ccccc3[nH]2 InChI=1/C11H8N2O/c1-2-5-9-8(4-1)12-11(13-9)10-6-3-7-14-10/h1-7H,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fuberidazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fuberidazole 09Jan2008 2008 doi:10.2903/j.efsa.2008.118r
+Fuberidazole 223-404-0 3878-19-1 single chemical entity Component is identical to the substance Fuberidazole 223-404-0 3878-19-1 2-(2-furyl)-1H-benzimidazole Fuberidazole C11H8N2O o1cccc1c2nc3ccccc3[nH]2 InChI=1/C11H8N2O/c1-2-5-9-8(4-1)12-11(13-9)10-6-3-7-14-10/h1-7H,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fuberidazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fuberidazole 09Jan2008 2008 doi:10.2903/j.efsa.2008.118r
+Fuberidazole 223-404-0 3878-19-1 single chemical entity Component is identical to the substance Fuberidazole 223-404-0 3878-19-1 2-(2-furyl)-1H-benzimidazole Fuberidazole C11H8N2O o1cccc1c2nc3ccccc3[nH]2 InChI=1/C11H8N2O/c1-2-5-9-8(4-1)12-11(13-9)10-6-3-7-14-10/h1-7H,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fuberidazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fuberidazole 09Jan2008 2008 doi:10.2903/j.efsa.2008.118r
+Fuberidazole 223-404-0 3878-19-1 single chemical entity Component is identical to the substance Fuberidazole 223-404-0 3878-19-1 2-(2-furyl)-1H-benzimidazole Fuberidazole C11H8N2O o1cccc1c2nc3ccccc3[nH]2 InChI=1/C11H8N2O/c1-2-5-9-8(4-1)12-11(13-9)10-6-3-7-14-10/h1-7H,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fuberidazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fuberidazole 09Jan2008 2008 doi:10.2903/j.efsa.2008.118r
+Fuberidazole 223-404-0 3878-19-1 single chemical entity Component is identical to the substance Fuberidazole 223-404-0 3878-19-1 2-(2-furyl)-1H-benzimidazole Fuberidazole C11H8N2O o1cccc1c2nc3ccccc3[nH]2 InChI=1/C11H8N2O/c1-2-5-9-8(4-1)12-11(13-9)10-6-3-7-14-10/h1-7H,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fuberidazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fuberidazole 09Jan2008 2008 doi:10.2903/j.efsa.2008.118r
+Fuberidazole 223-404-0 3878-19-1 single chemical entity Component is identical to the substance Fuberidazole 223-404-0 3878-19-1 2-(2-furyl)-1H-benzimidazole Fuberidazole C11H8N2O o1cccc1c2nc3ccccc3[nH]2 InChI=1/C11H8N2O/c1-2-5-9-8(4-1)12-11(13-9)10-6-3-7-14-10/h1-7H,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fuberidazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fuberidazole 09Jan2008 2008 doi:10.2903/j.efsa.2008.118r
+Fuberidazole 223-404-0 3878-19-1 single chemical entity Component is identical to the substance Fuberidazole 223-404-0 3878-19-1 2-(2-furyl)-1H-benzimidazole Fuberidazole C11H8N2O o1cccc1c2nc3ccccc3[nH]2 InChI=1/C11H8N2O/c1-2-5-9-8(4-1)12-11(13-9)10-6-3-7-14-10/h1-7H,(H,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fuberidazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fuberidazole 09Jan2008 2008 doi:10.2903/j.efsa.2008.118r
+Fuberidazole 223-404-0 3878-19-1 single chemical entity Component is identical to the substance Fuberidazole 223-404-0 3878-19-1 2-(2-furyl)-1H-benzimidazole Fuberidazole C11H8N2O o1cccc1c2nc3ccccc3[nH]2 InChI=1/C11H8N2O/c1-2-5-9-8(4-1)12-11(13-9)10-6-3-7-14-10/h1-7H,(H,12,13) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fuberidazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fuberidazole 09Jan2008 2008 doi:10.2903/j.efsa.2008.118r
+Fuberidazole 223-404-0 3878-19-1 single chemical entity Component is identical to the substance Fuberidazole 223-404-0 3878-19-1 2-(2-furyl)-1H-benzimidazole Fuberidazole C11H8N2O o1cccc1c2nc3ccccc3[nH]2 InChI=1/C11H8N2O/c1-2-5-9-8(4-1)12-11(13-9)10-6-3-7-14-10/h1-7H,(H,12,13) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fuberidazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fuberidazole 09Jan2008 2008 doi:10.2903/j.efsa.2008.118r
+Fuberidazole 223-404-0 3878-19-1 single chemical entity Component is identical to the substance Fuberidazole 223-404-0 3878-19-1 2-(2-furyl)-1H-benzimidazole Fuberidazole C11H8N2O o1cccc1c2nc3ccccc3[nH]2 InChI=1/C11H8N2O/c1-2-5-9-8(4-1)12-11(13-9)10-6-3-7-14-10/h1-7H,(H,12,13) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: The United Kingdom Fuberidazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fuberidazole 09Jan2008 2008 doi:10.2903/j.efsa.2008.118r
+Fuberidazole 223-404-0 3878-19-1 single chemical entity Component is identical to the substance Fuberidazole 223-404-0 3878-19-1 2-(2-furyl)-1H-benzimidazole Fuberidazole C11H8N2O o1cccc1c2nc3ccccc3[nH]2 InChI=1/C11H8N2O/c1-2-5-9-8(4-1)12-11(13-9)10-6-3-7-14-10/h1-7H,(H,12,13) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes with Positive RMS: The United Kingdom Fuberidazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fuberidazole 09Jan2008 2008 doi:10.2903/j.efsa.2008.118r
+Fuberidazole 223-404-0 3878-19-1 single chemical entity Component is identical to the substance Fuberidazole 223-404-0 3878-19-1 2-(2-furyl)-1H-benzimidazole Fuberidazole C11H8N2O o1cccc1c2nc3ccccc3[nH]2 InChI=1/C11H8N2O/c1-2-5-9-8(4-1)12-11(13-9)10-6-3-7-14-10/h1-7H,(H,12,13) organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported no data without Negative RMS: The United Kingdom Fuberidazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fuberidazole 09Jan2008 2008 doi:10.2903/j.efsa.2008.118r
+Fuberidazole 223-404-0 3878-19-1 single chemical entity Component is identical to the substance Fuberidazole 223-404-0 3878-19-1 2-(2-furyl)-1H-benzimidazole Fuberidazole C11H8N2O o1cccc1c2nc3ccccc3[nH]2 InChI=1/C11H8N2O/c1-2-5-9-8(4-1)12-11(13-9)10-6-3-7-14-10/h1-7H,(H,12,13) organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported no data with Negative RMS: The United Kingdom Fuberidazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fuberidazole 09Jan2008 2008 doi:10.2903/j.efsa.2008.118r
+Fuberidazole 223-404-0 3878-19-1 single chemical entity Component is identical to the substance Fuberidazole 223-404-0 3878-19-1 2-(2-furyl)-1H-benzimidazole Fuberidazole C11H8N2O o1cccc1c2nc3ccccc3[nH]2 InChI=1/C11H8N2O/c1-2-5-9-8(4-1)12-11(13-9)10-6-3-7-14-10/h1-7H,(H,12,13) organic compound Other Other chromosome aberration dominant lethal assay in vivo According to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) No Acceptable House mouse (as animal) NMRI 20 Male oral: unspecified 8.0000000000 week no data not applicable Negative RMS: The United Kingdom Fuberidazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fuberidazole 09Jan2008 2008 doi:10.2903/j.efsa.2008.118r
+Fuberidazole 223-404-0 3878-19-1 single chemical entity Component is identical to the substance Fuberidazole 223-404-0 3878-19-1 2-(2-furyl)-1H-benzimidazole Fuberidazole C11H8N2O o1cccc1c2nc3ccccc3[nH]2 InChI=1/C11H8N2O/c1-2-5-9-8(4-1)12-11(13-9)10-6-3-7-14-10/h1-7H,(H,12,13) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI Male/Female oral: unspecified 48.0000000000 h no data not applicable Negative no evidence RMS: The United Kingdom Fuberidazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fuberidazole 09Jan2008 2008 doi:10.2903/j.efsa.2008.118r
+Fuberidazole 223-404-0 3878-19-1 single chemical entity Component is identical to the substance Fuberidazole 223-404-0 3878-19-1 2-(2-furyl)-1H-benzimidazole Fuberidazole C11H8N2O o1cccc1c2nc3ccccc3[nH]2 InChI=1/C11H8N2O/c1-2-5-9-8(4-1)12-11(13-9)10-6-3-7-14-10/h1-7H,(H,12,13) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI Male/Female oral: unspecified 24.0000000000 h no data not applicable Negative no evidence RMS: The United Kingdom Fuberidazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fuberidazole 09Jan2008 2008 doi:10.2903/j.efsa.2008.118r
+Fuberidazole 223-404-0 3878-19-1 single chemical entity Component is identical to the substance Fuberidazole 223-404-0 3878-19-1 2-(2-furyl)-1H-benzimidazole Fuberidazole C11H8N2O o1cccc1c2nc3ccccc3[nH]2 InChI=1/C11H8N2O/c1-2-5-9-8(4-1)12-11(13-9)10-6-3-7-14-10/h1-7H,(H,12,13) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI Male/Female intraperitoneal 72.0000000000 h no data not applicable Negative no evidence RMS: The United Kingdom Fuberidazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fuberidazole 09Jan2008 2008 doi:10.2903/j.efsa.2008.118r
+Fuberidazole 223-404-0 3878-19-1 single chemical entity Component is identical to the substance Fuberidazole 223-404-0 3878-19-1 2-(2-furyl)-1H-benzimidazole Fuberidazole C11H8N2O o1cccc1c2nc3ccccc3[nH]2 InChI=1/C11H8N2O/c1-2-5-9-8(4-1)12-11(13-9)10-6-3-7-14-10/h1-7H,(H,12,13) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI Male/Female intraperitoneal 48.0000000000 h no data not applicable Negative no evidence RMS: The United Kingdom Fuberidazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fuberidazole 09Jan2008 2008 doi:10.2903/j.efsa.2008.118r
+Fuberidazole 223-404-0 3878-19-1 single chemical entity Component is identical to the substance Fuberidazole 223-404-0 3878-19-1 2-(2-furyl)-1H-benzimidazole Fuberidazole C11H8N2O o1cccc1c2nc3ccccc3[nH]2 InChI=1/C11H8N2O/c1-2-5-9-8(4-1)12-11(13-9)10-6-3-7-14-10/h1-7H,(H,12,13) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI Male/Female intraperitoneal 24.0000000000 h no data not applicable Negative no evidence RMS: The United Kingdom Fuberidazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fuberidazole 09Jan2008 2008 doi:10.2903/j.efsa.2008.118r
+Fuberidazole 223-404-0 3878-19-1 single chemical entity Component is identical to the substance Fuberidazole 223-404-0 3878-19-1 2-(2-furyl)-1H-benzimidazole Fuberidazole C11H8N2O o1cccc1c2nc3ccccc3[nH]2 InChI=1/C11H8N2O/c1-2-5-9-8(4-1)12-11(13-9)10-6-3-7-14-10/h1-7H,(H,12,13) organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vivo No guideline available Not reported Not applicable Acceptable Hamster (as animal) Chinese 10 Male/Female intraperitoneal yes not applicable Negative RMS: The United Kingdom Fuberidazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fuberidazole 09Jan2008 2008 doi:10.2903/j.efsa.2008.118r
+Fuberidazole 223-404-0 3878-19-1 single chemical entity Component is identical to the substance Fuberidazole 223-404-0 3878-19-1 2-(2-furyl)-1H-benzimidazole Fuberidazole C11H8N2O o1cccc1c2nc3ccccc3[nH]2 InChI=1/C11H8N2O/c1-2-5-9-8(4-1)12-11(13-9)10-6-3-7-14-10/h1-7H,(H,12,13) organic compound Other Other chromosome aberration in vitro mammalian cell micronucleus test in vitro Equivalent or similar to OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes with Positive RMS: The United Kingdom Fuberidazole (Final addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fuberidazole 09Jan2008 2008 doi:10.2903/j.efsa.2008.118r
+Fuberidazole 223-404-0 3878-19-1 single chemical entity Component is identical to the substance Fuberidazole 223-404-0 3878-19-1 2-(2-furyl)-1H-benzimidazole Fuberidazole C11H8N2O o1cccc1c2nc3ccccc3[nH]2 InChI=1/C11H8N2O/c1-2-5-9-8(4-1)12-11(13-9)10-6-3-7-14-10/h1-7H,(H,12,13) organic compound Other Other chromosome aberration in vitro mammalian cell micronucleus test in vitro Equivalent or similar to OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes without Positive RMS: The United Kingdom Fuberidazole (Final addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fuberidazole 09Jan2008 2008 doi:10.2903/j.efsa.2008.118r
+Fuberidazole 223-404-0 3878-19-1 single chemical entity Component is identical to the substance Fuberidazole 223-404-0 3878-19-1 2-(2-furyl)-1H-benzimidazole Fuberidazole C11H8N2O o1cccc1c2nc3ccccc3[nH]2 InChI=1/C11H8N2O/c1-2-5-9-8(4-1)12-11(13-9)10-6-3-7-14-10/h1-7H,(H,12,13) organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Rat (as animal) Not reported 6 Male oral: gavage 16.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Fuberidazole (Final addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fuberidazole 09Jan2008 2008 doi:10.2903/j.efsa.2008.118r
+Fuberidazole 223-404-0 3878-19-1 single chemical entity Component is identical to the substance Fuberidazole 223-404-0 3878-19-1 2-(2-furyl)-1H-benzimidazole Fuberidazole C11H8N2O o1cccc1c2nc3ccccc3[nH]2 InChI=1/C11H8N2O/c1-2-5-9-8(4-1)12-11(13-9)10-6-3-7-14-10/h1-7H,(H,12,13) organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Rat (as animal) Not reported 6 Male oral: gavage 42.0000000000 h yes, concurrent vehicle not applicable Negative RMS: The United Kingdom Fuberidazole (Final addendum) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fuberidazole 09Jan2008 2008 doi:10.2903/j.efsa.2008.118r
+Fenoxaprop-P-ethyl 71283-80-2 single chemical entity Component is identical to the substance Fenoxaprop-P-ethyl 71283-80-2 Ethyl (2R)-2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate Fenoxaprop-P-Ethyl C18H16ClNO5 CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3/t11-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Austria Fenoxaprop-P-ethyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P 13Dec2007 2007 doi:10.2903/j.efsa.2007.121r
+Fenoxaprop-P-ethyl 71283-80-2 single chemical entity Component is identical to the substance Fenoxaprop-P-ethyl 71283-80-2 Ethyl (2R)-2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate Fenoxaprop-P-Ethyl C18H16ClNO5 CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3/t11-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Austria Fenoxaprop-P-ethyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P 13Dec2007 2007 doi:10.2903/j.efsa.2007.121r
+Fenoxaprop-P-ethyl 71283-80-2 single chemical entity Component is identical to the substance Fenoxaprop-P-ethyl 71283-80-2 Ethyl (2R)-2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate Fenoxaprop-P-Ethyl C18H16ClNO5 CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3/t11-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Austria Fenoxaprop-P-ethyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P 13Dec2007 2007 doi:10.2903/j.efsa.2007.121r
+Fenoxaprop-P-ethyl 71283-80-2 single chemical entity Component is identical to the substance Fenoxaprop-P-ethyl 71283-80-2 Ethyl (2R)-2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate Fenoxaprop-P-Ethyl C18H16ClNO5 CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3/t11-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Austria Fenoxaprop-P-ethyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P 13Dec2007 2007 doi:10.2903/j.efsa.2007.121r
+Fenoxaprop-P-ethyl 71283-80-2 single chemical entity Component is identical to the substance Fenoxaprop-P-ethyl 71283-80-2 Ethyl (2R)-2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate Fenoxaprop-P-Ethyl C18H16ClNO5 CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3/t11-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Austria Fenoxaprop-P-ethyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P 13Dec2007 2007 doi:10.2903/j.efsa.2007.121r
+Fenoxaprop-P-ethyl 71283-80-2 single chemical entity Component is identical to the substance Fenoxaprop-P-ethyl 71283-80-2 Ethyl (2R)-2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate Fenoxaprop-P-Ethyl C18H16ClNO5 CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3/t11-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Austria Fenoxaprop-P-ethyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P 13Dec2007 2007 doi:10.2903/j.efsa.2007.121r
+Fenoxaprop-P-ethyl 71283-80-2 single chemical entity Component is identical to the substance Fenoxaprop-P-ethyl 71283-80-2 Ethyl (2R)-2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate Fenoxaprop-P-Ethyl C18H16ClNO5 CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3/t11-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Austria Fenoxaprop-P-ethyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P 13Dec2007 2007 doi:10.2903/j.efsa.2007.121r
+Fenoxaprop-P-ethyl 71283-80-2 single chemical entity Component is identical to the substance Fenoxaprop-P-ethyl 71283-80-2 Ethyl (2R)-2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate Fenoxaprop-P-Ethyl C18H16ClNO5 CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3/t11-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Austria Fenoxaprop-P-ethyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P 13Dec2007 2007 doi:10.2903/j.efsa.2007.121r
+Fenoxaprop-P-ethyl 71283-80-2 single chemical entity Component is identical to the substance Fenoxaprop-P-ethyl 71283-80-2 Ethyl (2R)-2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate Fenoxaprop-P-Ethyl C18H16ClNO5 CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3/t11-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Austria Fenoxaprop-P-ethyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P 13Dec2007 2007 doi:10.2903/j.efsa.2007.121r
+Fenoxaprop-P-ethyl 71283-80-2 single chemical entity Component is identical to the substance Fenoxaprop-P-ethyl 71283-80-2 Ethyl (2R)-2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate Fenoxaprop-P-Ethyl C18H16ClNO5 CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3/t11-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Austria Fenoxaprop-P-ethyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P 13Dec2007 2007 doi:10.2903/j.efsa.2007.121r
+Fenoxaprop-P-ethyl 71283-80-2 single chemical entity Component is identical to the substance Fenoxaprop-P-ethyl 71283-80-2 Ethyl (2R)-2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate Fenoxaprop-P-Ethyl C18H16ClNO5 CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3/t11-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Schizosaccharomyces pombe (as organism) Not reported Not reported yes, concurrent vehicle without Negative RMS: Austria Fenoxaprop-P-ethyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P 13Dec2007 2007 doi:10.2903/j.efsa.2007.121r
+Fenoxaprop-P-ethyl 71283-80-2 single chemical entity Component is identical to the substance Fenoxaprop-P-ethyl 71283-80-2 Ethyl (2R)-2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate Fenoxaprop-P-Ethyl C18H16ClNO5 CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3/t11-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Schizosaccharomyces pombe (as organism) Not reported Not reported yes, concurrent vehicle with Negative RMS: Austria Fenoxaprop-P-ethyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P 13Dec2007 2007 doi:10.2903/j.efsa.2007.121r
+Fenoxaprop-P-ethyl 71283-80-2 single chemical entity Component is identical to the substance Fenoxaprop-P-ethyl 71283-80-2 Ethyl (2R)-2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate Fenoxaprop-P-Ethyl C18H16ClNO5 CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3/t11-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Negative RMS: Austria Fenoxaprop-P-ethyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P 13Dec2007 2007 doi:10.2903/j.efsa.2007.121r
+Fenoxaprop-P-ethyl 71283-80-2 single chemical entity Component is identical to the substance Fenoxaprop-P-ethyl 71283-80-2 Ethyl (2R)-2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate Fenoxaprop-P-Ethyl C18H16ClNO5 CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3/t11-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Negative RMS: Austria Fenoxaprop-P-ethyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P 13Dec2007 2007 doi:10.2903/j.efsa.2007.121r
+Fenoxaprop-P-ethyl 71283-80-2 single chemical entity Component is identical to the substance Fenoxaprop-P-ethyl 71283-80-2 Ethyl (2R)-2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate Fenoxaprop-P-Ethyl C18H16ClNO5 CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3/t11-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Austria Fenoxaprop-P-ethyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P 13Dec2007 2007 doi:10.2903/j.efsa.2007.121r
+Fenoxaprop-P-ethyl 71283-80-2 single chemical entity Component is identical to the substance Fenoxaprop-P-ethyl 71283-80-2 Ethyl (2R)-2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate Fenoxaprop-P-Ethyl C18H16ClNO5 CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3/t11-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Austria Fenoxaprop-P-ethyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P 13Dec2007 2007 doi:10.2903/j.efsa.2007.121r
+Fenoxaprop-P-ethyl 71283-80-2 single chemical entity Component is identical to the substance Fenoxaprop-P-ethyl 71283-80-2 Ethyl (2R)-2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate Fenoxaprop-P-Ethyl C18H16ClNO5 CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3/t11-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro According to OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay) No Acceptable Saccharomyces cerevisiae (as organism) D4 Not reported yes without Negative RMS: Austria Fenoxaprop-P-ethyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P 13Dec2007 2007 doi:10.2903/j.efsa.2007.121r
+Fenoxaprop-P-ethyl 71283-80-2 single chemical entity Component is identical to the substance Fenoxaprop-P-ethyl 71283-80-2 Ethyl (2R)-2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate Fenoxaprop-P-Ethyl C18H16ClNO5 CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3/t11-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro According to OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay) No Acceptable Saccharomyces cerevisiae (as organism) D4 Not reported yes with Negative RMS: Austria Fenoxaprop-P-ethyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P 13Dec2007 2007 doi:10.2903/j.efsa.2007.121r
+Fenoxaprop-P-ethyl 71283-80-2 single chemical entity Component is identical to the substance Fenoxaprop-P-ethyl 71283-80-2 Ethyl (2R)-2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate Fenoxaprop-P-Ethyl C18H16ClNO5 CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3/t11-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Rat (as animal) hepatocytes Not reported yes without Negative RMS: Austria Fenoxaprop-P-ethyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P 13Dec2007 2007 doi:10.2903/j.efsa.2007.121r
+Fenoxaprop-P-ethyl 71283-80-2 single chemical entity Component is identical to the substance Fenoxaprop-P-ethyl 71283-80-2 Ethyl (2R)-2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate Fenoxaprop-P-Ethyl C18H16ClNO5 CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3/t11-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Human (as organism) alveolar basal epithelial cells (A549) Not reported yes without Negative RMS: Austria Fenoxaprop-P-ethyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P 13Dec2007 2007 doi:10.2903/j.efsa.2007.121r
+Fenoxaprop-P-ethyl 71283-80-2 single chemical entity Component is identical to the substance Fenoxaprop-P-ethyl 71283-80-2 Ethyl (2R)-2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate Fenoxaprop-P-Ethyl C18H16ClNO5 CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3/t11-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Human (as organism) alveolar basal epithelial cells (A549) Not reported yes with Negative RMS: Austria Fenoxaprop-P-ethyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P 13Dec2007 2007 doi:10.2903/j.efsa.2007.121r
+Fenoxaprop-P-ethyl 71283-80-2 single chemical entity Component is identical to the substance Fenoxaprop-P-ethyl 71283-80-2 Ethyl (2R)-2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate Fenoxaprop-P-Ethyl C18H16ClNO5 CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3/t11-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 72.0000000000 h yes not applicable Negative no evidence RMS: Austria Fenoxaprop-P-ethyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P 13Dec2007 2007 doi:10.2903/j.efsa.2007.121r
+Fenoxaprop-P-ethyl 71283-80-2 single chemical entity Component is identical to the substance Fenoxaprop-P-ethyl 71283-80-2 Ethyl (2R)-2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate Fenoxaprop-P-Ethyl C18H16ClNO5 CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3/t11-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 48.0000000000 h yes not applicable Negative no evidence RMS: Austria Fenoxaprop-P-ethyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P 13Dec2007 2007 doi:10.2903/j.efsa.2007.121r
+Fenoxaprop-P-ethyl 71283-80-2 single chemical entity Component is identical to the substance Fenoxaprop-P-ethyl 71283-80-2 Ethyl (2R)-2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate Fenoxaprop-P-Ethyl C18H16ClNO5 CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3/t11-/m1/s1 organic compound PubChem isomeric SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 24.0000000000 h yes not applicable Negative no evidence RMS: Austria Fenoxaprop-P-ethyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P 13Dec2007 2007 doi:10.2903/j.efsa.2007.121r
+Fenoxaprop-P-ethyl 71283-80-2 single chemical entity Component is part of a group assessment Fenoxaprop-ethyl 266-362-9 66441-23-4 Ethyl 2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate Fenoxaprop-ethyl C18H16ClNO5 CCOC(=O)C(C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Austria Fenoxaprop-P-ethyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P 13Dec2007 2007 doi:10.2903/j.efsa.2007.121r
+Fenoxaprop-P-ethyl 71283-80-2 single chemical entity Component is part of a group assessment Fenoxaprop-ethyl 266-362-9 66441-23-4 Ethyl 2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate Fenoxaprop-ethyl C18H16ClNO5 CCOC(=O)C(C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Austria Fenoxaprop-P-ethyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P 13Dec2007 2007 doi:10.2903/j.efsa.2007.121r
+Fenoxaprop-P-ethyl 71283-80-2 single chemical entity Component is part of a group assessment Fenoxaprop-ethyl 266-362-9 66441-23-4 Ethyl 2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate Fenoxaprop-ethyl C18H16ClNO5 CCOC(=O)C(C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Austria Fenoxaprop-P-ethyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P 13Dec2007 2007 doi:10.2903/j.efsa.2007.121r
+Fenoxaprop-P-ethyl 71283-80-2 single chemical entity Component is part of a group assessment Fenoxaprop-ethyl 266-362-9 66441-23-4 Ethyl 2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate Fenoxaprop-ethyl C18H16ClNO5 CCOC(=O)C(C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Austria Fenoxaprop-P-ethyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P 13Dec2007 2007 doi:10.2903/j.efsa.2007.121r
+Fenoxaprop-P-ethyl 71283-80-2 single chemical entity Component is part of a group assessment Fenoxaprop-ethyl 266-362-9 66441-23-4 Ethyl 2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate Fenoxaprop-ethyl C18H16ClNO5 CCOC(=O)C(C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Austria Fenoxaprop-P-ethyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P 13Dec2007 2007 doi:10.2903/j.efsa.2007.121r
+Fenoxaprop-P-ethyl 71283-80-2 single chemical entity Component is part of a group assessment Fenoxaprop-ethyl 266-362-9 66441-23-4 Ethyl 2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate Fenoxaprop-ethyl C18H16ClNO5 CCOC(=O)C(C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Austria Fenoxaprop-P-ethyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P 13Dec2007 2007 doi:10.2903/j.efsa.2007.121r
+Fenoxaprop-P-ethyl 71283-80-2 single chemical entity Component is part of a group assessment Fenoxaprop-ethyl 266-362-9 66441-23-4 Ethyl 2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate Fenoxaprop-ethyl C18H16ClNO5 CCOC(=O)C(C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Austria Fenoxaprop-P-ethyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P 13Dec2007 2007 doi:10.2903/j.efsa.2007.121r
+Fenoxaprop-P-ethyl 71283-80-2 single chemical entity Component is part of a group assessment Fenoxaprop-ethyl 266-362-9 66441-23-4 Ethyl 2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate Fenoxaprop-ethyl C18H16ClNO5 CCOC(=O)C(C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Austria Fenoxaprop-P-ethyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P 13Dec2007 2007 doi:10.2903/j.efsa.2007.121r
+Fenoxaprop-P-ethyl 71283-80-2 single chemical entity Component is part of a group assessment Fenoxaprop-ethyl 266-362-9 66441-23-4 Ethyl 2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate Fenoxaprop-ethyl C18H16ClNO5 CCOC(=O)C(C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Austria Fenoxaprop-P-ethyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P 13Dec2007 2007 doi:10.2903/j.efsa.2007.121r
+Fenoxaprop-P-ethyl 71283-80-2 single chemical entity Component is part of a group assessment Fenoxaprop-ethyl 266-362-9 66441-23-4 Ethyl 2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate Fenoxaprop-ethyl C18H16ClNO5 CCOC(=O)C(C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Austria Fenoxaprop-P-ethyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P 13Dec2007 2007 doi:10.2903/j.efsa.2007.121r
+Fenoxaprop-P-ethyl 71283-80-2 single chemical entity Component is part of a group assessment Fenoxaprop-ethyl 266-362-9 66441-23-4 Ethyl 2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate Fenoxaprop-ethyl C18H16ClNO5 CCOC(=O)C(C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Austria Fenoxaprop-P-ethyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P 13Dec2007 2007 doi:10.2903/j.efsa.2007.121r
+Fenoxaprop-P-ethyl 71283-80-2 single chemical entity Component is part of a group assessment Fenoxaprop-ethyl 266-362-9 66441-23-4 Ethyl 2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate Fenoxaprop-ethyl C18H16ClNO5 CCOC(=O)C(C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Austria Fenoxaprop-P-ethyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P 13Dec2007 2007 doi:10.2903/j.efsa.2007.121r
+Fenoxaprop-P-ethyl 71283-80-2 single chemical entity Component is part of a group assessment Fenoxaprop-ethyl 266-362-9 66441-23-4 Ethyl 2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate Fenoxaprop-ethyl C18H16ClNO5 CCOC(=O)C(C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Schizosaccharomyces pombe (as organism) Not reported Not reported yes, concurrent vehicle without Negative RMS: Austria Fenoxaprop-P-ethyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P 13Dec2007 2007 doi:10.2903/j.efsa.2007.121r
+Fenoxaprop-P-ethyl 71283-80-2 single chemical entity Component is part of a group assessment Fenoxaprop-ethyl 266-362-9 66441-23-4 Ethyl 2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate Fenoxaprop-ethyl C18H16ClNO5 CCOC(=O)C(C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Schizosaccharomyces pombe (as organism) Not reported Not reported yes, concurrent vehicle with Negative RMS: Austria Fenoxaprop-P-ethyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P 13Dec2007 2007 doi:10.2903/j.efsa.2007.121r
+Fenoxaprop-P-ethyl 71283-80-2 single chemical entity Component is part of a group assessment Fenoxaprop-ethyl 266-362-9 66441-23-4 Ethyl 2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate Fenoxaprop-ethyl C18H16ClNO5 CCOC(=O)C(C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Austria Fenoxaprop-P-ethyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P 13Dec2007 2007 doi:10.2903/j.efsa.2007.121r
+Fenoxaprop-P-ethyl 71283-80-2 single chemical entity Component is part of a group assessment Fenoxaprop-ethyl 266-362-9 66441-23-4 Ethyl 2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate Fenoxaprop-ethyl C18H16ClNO5 CCOC(=O)C(C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Austria Fenoxaprop-P-ethyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P 13Dec2007 2007 doi:10.2903/j.efsa.2007.121r
+Fenoxaprop-P-ethyl 71283-80-2 single chemical entity Component is part of a group assessment Fenoxaprop-ethyl 266-362-9 66441-23-4 Ethyl 2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate Fenoxaprop-ethyl C18H16ClNO5 CCOC(=O)C(C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro According to OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay) No Acceptable Saccharomyces cerevisiae (as organism) D4 Not reported yes without Negative RMS: Austria Fenoxaprop-P-ethyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P 13Dec2007 2007 doi:10.2903/j.efsa.2007.121r
+Fenoxaprop-P-ethyl 71283-80-2 single chemical entity Component is part of a group assessment Fenoxaprop-ethyl 266-362-9 66441-23-4 Ethyl 2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate Fenoxaprop-ethyl C18H16ClNO5 CCOC(=O)C(C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro According to OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay) No Acceptable Saccharomyces cerevisiae (as organism) D4 Not reported yes with Negative RMS: Austria Fenoxaprop-P-ethyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P 13Dec2007 2007 doi:10.2903/j.efsa.2007.121r
+Fenoxaprop-P-ethyl 71283-80-2 single chemical entity Component is part of a group assessment Fenoxaprop-ethyl 266-362-9 66441-23-4 Ethyl 2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate Fenoxaprop-ethyl C18H16ClNO5 CCOC(=O)C(C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Human (as organism) HeLa cells Not reported yes, concurrent vehicle without Negative RMS: Austria Fenoxaprop-P-ethyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P 13Dec2007 2007 doi:10.2903/j.efsa.2007.121r
+Fenoxaprop-P-ethyl 71283-80-2 single chemical entity Component is part of a group assessment Fenoxaprop-ethyl 266-362-9 66441-23-4 Ethyl 2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate Fenoxaprop-ethyl C18H16ClNO5 CCOC(=O)C(C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Human (as organism) HeLa cells Not reported yes, concurrent vehicle with Negative RMS: Austria Fenoxaprop-P-ethyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P 13Dec2007 2007 doi:10.2903/j.efsa.2007.121r
+Fenoxaprop-P-ethyl 71283-80-2 single chemical entity Component is part of a group assessment Fenoxaprop-ethyl 266-362-9 66441-23-4 Ethyl 2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate Fenoxaprop-ethyl C18H16ClNO5 CCOC(=O)C(C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 12 Male/Female oral: gavage 48.0000000000 h yes not applicable Negative no evidence RMS: Austria Fenoxaprop-P-ethyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P 13Dec2007 2007 doi:10.2903/j.efsa.2007.121r
+Fenoxaprop-P-ethyl 71283-80-2 single chemical entity Component is part of a group assessment Fenoxaprop-ethyl 266-362-9 66441-23-4 Ethyl 2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate Fenoxaprop-ethyl C18H16ClNO5 CCOC(=O)C(C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 12 Male/Female oral: gavage 24.0000000000 h yes not applicable Negative no evidence RMS: Austria Fenoxaprop-P-ethyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P 13Dec2007 2007 doi:10.2903/j.efsa.2007.121r
+Fenoxaprop-P-ethyl 71283-80-2 single chemical entity Component is part of a group assessment Fenoxaprop-ethyl 266-362-9 66441-23-4 Ethyl 2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate Fenoxaprop-ethyl C18H16ClNO5 CCOC(=O)C(C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 12 Male/Female oral: gavage 72.0000000000 h yes not applicable Negative no evidence RMS: Austria Fenoxaprop-P-ethyl 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P 13Dec2007 2007 doi:10.2903/j.efsa.2007.121r
+Fluroxypyr-meptyl 279-752-9 81406-37-3 single chemical entity Component is identical to the substance Fluroxypyr-meptyl 279-752-9 81406-37-3 Octan-2-yl 2-(4-amino-3,5-dichloro-6-fluoropyridin-2-yl)oxyacetate Fluroxypyr-Meptyl C15H21Cl2FN2O3 CCCCCCC(C)OC(=O)COC1=NC(=C(C(=C1Cl)N)Cl)F InChI=1S/C15H21Cl2FN2O3/c1-3-4-5-6-7-9(2)23-10(21)8-22-15-12(17)13(19)11(16)14(18)20-15/h9H,3-8H2,1-2H3,(H2,19,20) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Germany Fluroxypyr 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluroxypyr (evaluated variant fluroxypyr-meptyl) 08Mar2011 2011 doi:10.2903/j.efsa.2011.2091
+Fluroxypyr-meptyl 279-752-9 81406-37-3 single chemical entity Component is identical to the substance Fluroxypyr-meptyl 279-752-9 81406-37-3 Octan-2-yl 2-(4-amino-3,5-dichloro-6-fluoropyridin-2-yl)oxyacetate Fluroxypyr-Meptyl C15H21Cl2FN2O3 CCCCCCC(C)OC(=O)COC1=NC(=C(C(=C1Cl)N)Cl)F InChI=1S/C15H21Cl2FN2O3/c1-3-4-5-6-7-9(2)23-10(21)8-22-15-12(17)13(19)11(16)14(18)20-15/h9H,3-8H2,1-2H3,(H2,19,20) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany Fluroxypyr 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluroxypyr (evaluated variant fluroxypyr-meptyl) 08Mar2011 2011 doi:10.2903/j.efsa.2011.2091
+Fluroxypyr-meptyl 279-752-9 81406-37-3 single chemical entity Component is identical to the substance Fluroxypyr-meptyl 279-752-9 81406-37-3 Octan-2-yl 2-(4-amino-3,5-dichloro-6-fluoropyridin-2-yl)oxyacetate Fluroxypyr-Meptyl C15H21Cl2FN2O3 CCCCCCC(C)OC(=O)COC1=NC(=C(C(=C1Cl)N)Cl)F InChI=1S/C15H21Cl2FN2O3/c1-3-4-5-6-7-9(2)23-10(21)8-22-15-12(17)13(19)11(16)14(18)20-15/h9H,3-8H2,1-2H3,(H2,19,20) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany Fluroxypyr 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluroxypyr (evaluated variant fluroxypyr-meptyl) 08Mar2011 2011 doi:10.2903/j.efsa.2011.2091
+Fluroxypyr-meptyl 279-752-9 81406-37-3 single chemical entity Component is identical to the substance Fluroxypyr-meptyl 279-752-9 81406-37-3 Octan-2-yl 2-(4-amino-3,5-dichloro-6-fluoropyridin-2-yl)oxyacetate Fluroxypyr-Meptyl C15H21Cl2FN2O3 CCCCCCC(C)OC(=O)COC1=NC(=C(C(=C1Cl)N)Cl)F InChI=1S/C15H21Cl2FN2O3/c1-3-4-5-6-7-9(2)23-10(21)8-22-15-12(17)13(19)11(16)14(18)20-15/h9H,3-8H2,1-2H3,(H2,19,20) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Germany Fluroxypyr 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluroxypyr (evaluated variant fluroxypyr-meptyl) 08Mar2011 2011 doi:10.2903/j.efsa.2011.2091
+Fluroxypyr-meptyl 279-752-9 81406-37-3 single chemical entity Component is identical to the substance Fluroxypyr-meptyl 279-752-9 81406-37-3 Octan-2-yl 2-(4-amino-3,5-dichloro-6-fluoropyridin-2-yl)oxyacetate Fluroxypyr-Meptyl C15H21Cl2FN2O3 CCCCCCC(C)OC(=O)COC1=NC(=C(C(=C1Cl)N)Cl)F InChI=1S/C15H21Cl2FN2O3/c1-3-4-5-6-7-9(2)23-10(21)8-22-15-12(17)13(19)11(16)14(18)20-15/h9H,3-8H2,1-2H3,(H2,19,20) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany Fluroxypyr 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluroxypyr (evaluated variant fluroxypyr-meptyl) 08Mar2011 2011 doi:10.2903/j.efsa.2011.2091
+Fluroxypyr-meptyl 279-752-9 81406-37-3 single chemical entity Component is identical to the substance Fluroxypyr-meptyl 279-752-9 81406-37-3 Octan-2-yl 2-(4-amino-3,5-dichloro-6-fluoropyridin-2-yl)oxyacetate Fluroxypyr-Meptyl C15H21Cl2FN2O3 CCCCCCC(C)OC(=O)COC1=NC(=C(C(=C1Cl)N)Cl)F InChI=1S/C15H21Cl2FN2O3/c1-3-4-5-6-7-9(2)23-10(21)8-22-15-12(17)13(19)11(16)14(18)20-15/h9H,3-8H2,1-2H3,(H2,19,20) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany Fluroxypyr 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluroxypyr (evaluated variant fluroxypyr-meptyl) 08Mar2011 2011 doi:10.2903/j.efsa.2011.2091
+Fluroxypyr-meptyl 279-752-9 81406-37-3 single chemical entity Component is identical to the substance Fluroxypyr-meptyl 279-752-9 81406-37-3 Octan-2-yl 2-(4-amino-3,5-dichloro-6-fluoropyridin-2-yl)oxyacetate Fluroxypyr-Meptyl C15H21Cl2FN2O3 CCCCCCC(C)OC(=O)COC1=NC(=C(C(=C1Cl)N)Cl)F InChI=1S/C15H21Cl2FN2O3/c1-3-4-5-6-7-9(2)23-10(21)8-22-15-12(17)13(19)11(16)14(18)20-15/h9H,3-8H2,1-2H3,(H2,19,20) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany Fluroxypyr 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluroxypyr (evaluated variant fluroxypyr-meptyl) 08Mar2011 2011 doi:10.2903/j.efsa.2011.2091
+Fluroxypyr-meptyl 279-752-9 81406-37-3 single chemical entity Component is identical to the substance Fluroxypyr-meptyl 279-752-9 81406-37-3 Octan-2-yl 2-(4-amino-3,5-dichloro-6-fluoropyridin-2-yl)oxyacetate Fluroxypyr-Meptyl C15H21Cl2FN2O3 CCCCCCC(C)OC(=O)COC1=NC(=C(C(=C1Cl)N)Cl)F InChI=1S/C15H21Cl2FN2O3/c1-3-4-5-6-7-9(2)23-10(21)8-22-15-12(17)13(19)11(16)14(18)20-15/h9H,3-8H2,1-2H3,(H2,19,20) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany Fluroxypyr 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluroxypyr (evaluated variant fluroxypyr-meptyl) 08Mar2011 2011 doi:10.2903/j.efsa.2011.2091
+Fluroxypyr-meptyl 279-752-9 81406-37-3 single chemical entity Component is identical to the substance Fluroxypyr-meptyl 279-752-9 81406-37-3 Octan-2-yl 2-(4-amino-3,5-dichloro-6-fluoropyridin-2-yl)oxyacetate Fluroxypyr-Meptyl C15H21Cl2FN2O3 CCCCCCC(C)OC(=O)COC1=NC(=C(C(=C1Cl)N)Cl)F InChI=1S/C15H21Cl2FN2O3/c1-3-4-5-6-7-9(2)23-10(21)8-22-15-12(17)13(19)11(16)14(18)20-15/h9H,3-8H2,1-2H3,(H2,19,20) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany Fluroxypyr 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluroxypyr (evaluated variant fluroxypyr-meptyl) 08Mar2011 2011 doi:10.2903/j.efsa.2011.2091
+Fluroxypyr-meptyl 279-752-9 81406-37-3 single chemical entity Component is identical to the substance Fluroxypyr-meptyl 279-752-9 81406-37-3 Octan-2-yl 2-(4-amino-3,5-dichloro-6-fluoropyridin-2-yl)oxyacetate Fluroxypyr-Meptyl C15H21Cl2FN2O3 CCCCCCC(C)OC(=O)COC1=NC(=C(C(=C1Cl)N)Cl)F InChI=1S/C15H21Cl2FN2O3/c1-3-4-5-6-7-9(2)23-10(21)8-22-15-12(17)13(19)11(16)14(18)20-15/h9H,3-8H2,1-2H3,(H2,19,20) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany Fluroxypyr 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluroxypyr (evaluated variant fluroxypyr-meptyl) 08Mar2011 2011 doi:10.2903/j.efsa.2011.2091
+Fluroxypyr-meptyl 279-752-9 81406-37-3 single chemical entity Component is identical to the substance Fluroxypyr-meptyl 279-752-9 81406-37-3 Octan-2-yl 2-(4-amino-3,5-dichloro-6-fluoropyridin-2-yl)oxyacetate Fluroxypyr-Meptyl C15H21Cl2FN2O3 CCCCCCC(C)OC(=O)COC1=NC(=C(C(=C1Cl)N)Cl)F InChI=1S/C15H21Cl2FN2O3/c1-3-4-5-6-7-9(2)23-10(21)8-22-15-12(17)13(19)11(16)14(18)20-15/h9H,3-8H2,1-2H3,(H2,19,20) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Positive no information RMS: Germany Fluroxypyr 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluroxypyr (evaluated variant fluroxypyr-meptyl) 08Mar2011 2011 doi:10.2903/j.efsa.2011.2091
+Fluroxypyr-meptyl 279-752-9 81406-37-3 single chemical entity Component is identical to the substance Fluroxypyr-meptyl 279-752-9 81406-37-3 Octan-2-yl 2-(4-amino-3,5-dichloro-6-fluoropyridin-2-yl)oxyacetate Fluroxypyr-Meptyl C15H21Cl2FN2O3 CCCCCCC(C)OC(=O)COC1=NC(=C(C(=C1Cl)N)Cl)F InChI=1S/C15H21Cl2FN2O3/c1-3-4-5-6-7-9(2)23-10(21)8-22-15-12(17)13(19)11(16)14(18)20-15/h9H,3-8H2,1-2H3,(H2,19,20) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Positive no information RMS: Germany Fluroxypyr 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluroxypyr (evaluated variant fluroxypyr-meptyl) 08Mar2011 2011 doi:10.2903/j.efsa.2011.2091
+Fluroxypyr-meptyl 279-752-9 81406-37-3 single chemical entity Component is identical to the substance Fluroxypyr-meptyl 279-752-9 81406-37-3 Octan-2-yl 2-(4-amino-3,5-dichloro-6-fluoropyridin-2-yl)oxyacetate Fluroxypyr-Meptyl C15H21Cl2FN2O3 CCCCCCC(C)OC(=O)COC1=NC(=C(C(=C1Cl)N)Cl)F InChI=1S/C15H21Cl2FN2O3/c1-3-4-5-6-7-9(2)23-10(21)8-22-15-12(17)13(19)11(16)14(18)20-15/h9H,3-8H2,1-2H3,(H2,19,20) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Germany Fluroxypyr 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluroxypyr (evaluated variant fluroxypyr-meptyl) 08Mar2011 2011 doi:10.2903/j.efsa.2011.2091
+Fluroxypyr-meptyl 279-752-9 81406-37-3 single chemical entity Component is identical to the substance Fluroxypyr-meptyl 279-752-9 81406-37-3 Octan-2-yl 2-(4-amino-3,5-dichloro-6-fluoropyridin-2-yl)oxyacetate Fluroxypyr-Meptyl C15H21Cl2FN2O3 CCCCCCC(C)OC(=O)COC1=NC(=C(C(=C1Cl)N)Cl)F InChI=1S/C15H21Cl2FN2O3/c1-3-4-5-6-7-9(2)23-10(21)8-22-15-12(17)13(19)11(16)14(18)20-15/h9H,3-8H2,1-2H3,(H2,19,20) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Germany Fluroxypyr 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluroxypyr (evaluated variant fluroxypyr-meptyl) 08Mar2011 2011 doi:10.2903/j.efsa.2011.2091
+Fluroxypyr-meptyl 279-752-9 81406-37-3 single chemical entity Component is identical to the substance Fluroxypyr-meptyl 279-752-9 81406-37-3 Octan-2-yl 2-(4-amino-3,5-dichloro-6-fluoropyridin-2-yl)oxyacetate Fluroxypyr-Meptyl C15H21Cl2FN2O3 CCCCCCC(C)OC(=O)COC1=NC(=C(C(=C1Cl)N)Cl)F InChI=1S/C15H21Cl2FN2O3/c1-3-4-5-6-7-9(2)23-10(21)8-22-15-12(17)13(19)11(16)14(18)20-15/h9H,3-8H2,1-2H3,(H2,19,20) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: Germany Fluroxypyr 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluroxypyr (evaluated variant fluroxypyr-meptyl) 08Mar2011 2011 doi:10.2903/j.efsa.2011.2091
+Fluroxypyr-meptyl 279-752-9 81406-37-3 single chemical entity Component is identical to the substance Fluroxypyr-meptyl 279-752-9 81406-37-3 Octan-2-yl 2-(4-amino-3,5-dichloro-6-fluoropyridin-2-yl)oxyacetate Fluroxypyr-Meptyl C15H21Cl2FN2O3 CCCCCCC(C)OC(=O)COC1=NC(=C(C(=C1Cl)N)Cl)F InChI=1S/C15H21Cl2FN2O3/c1-3-4-5-6-7-9(2)23-10(21)8-22-15-12(17)13(19)11(16)14(18)20-15/h9H,3-8H2,1-2H3,(H2,19,20) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: Germany Fluroxypyr 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluroxypyr (evaluated variant fluroxypyr-meptyl) 08Mar2011 2011 doi:10.2903/j.efsa.2011.2091
+Fluroxypyr-meptyl 279-752-9 81406-37-3 single chemical entity Component is identical to the substance Fluroxypyr-meptyl 279-752-9 81406-37-3 Octan-2-yl 2-(4-amino-3,5-dichloro-6-fluoropyridin-2-yl)oxyacetate Fluroxypyr-Meptyl C15H21Cl2FN2O3 CCCCCCC(C)OC(=O)COC1=NC(=C(C(=C1Cl)N)Cl)F InChI=1S/C15H21Cl2FN2O3/c1-3-4-5-6-7-9(2)23-10(21)8-22-15-12(17)13(19)11(16)14(18)20-15/h9H,3-8H2,1-2H3,(H2,19,20) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Human (as organism) fibroblast Not reported yes without Negative RMS: Germany Fluroxypyr 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluroxypyr (evaluated variant fluroxypyr-meptyl) 08Mar2011 2011 doi:10.2903/j.efsa.2011.2091
+Fluroxypyr-meptyl 279-752-9 81406-37-3 single chemical entity Component is identical to the substance Fluroxypyr-meptyl 279-752-9 81406-37-3 Octan-2-yl 2-(4-amino-3,5-dichloro-6-fluoropyridin-2-yl)oxyacetate Fluroxypyr-Meptyl C15H21Cl2FN2O3 CCCCCCC(C)OC(=O)COC1=NC(=C(C(=C1Cl)N)Cl)F InChI=1S/C15H21Cl2FN2O3/c1-3-4-5-6-7-9(2)23-10(21)8-22-15-12(17)13(19)11(16)14(18)20-15/h9H,3-8H2,1-2H3,(H2,19,20) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Human (as organism) fibroblast Not reported yes with Negative RMS: Germany Fluroxypyr 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluroxypyr (evaluated variant fluroxypyr-meptyl) 08Mar2011 2011 doi:10.2903/j.efsa.2011.2091
+Fluroxypyr-meptyl 279-752-9 81406-37-3 single chemical entity Component is identical to the substance Fluroxypyr-meptyl 279-752-9 81406-37-3 Octan-2-yl 2-(4-amino-3,5-dichloro-6-fluoropyridin-2-yl)oxyacetate Fluroxypyr-Meptyl C15H21Cl2FN2O3 CCCCCCC(C)OC(=O)COC1=NC(=C(C(=C1Cl)N)Cl)F InChI=1S/C15H21Cl2FN2O3/c1-3-4-5-6-7-9(2)23-10(21)8-22-15-12(17)13(19)11(16)14(18)20-15/h9H,3-8H2,1-2H3,(H2,19,20) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Hamster (as animal) Chinese 10 Male/Female oral: gavage 6.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Germany Fluroxypyr 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluroxypyr (evaluated variant fluroxypyr-meptyl) 08Mar2011 2011 doi:10.2903/j.efsa.2011.2091
+Ferric phosphate 233-149-7 10045-86-0 single chemical entity Component is identical to the substance Ferric phosphate 233-149-7 10045-86-0 iron(3+);phosphate Not in list FePO4 [O-]P(=O)([O-])[O-].[Fe+3] InChI=1S/Fe.H3O4P/c;1-5(2,3)4/h;(H3,1,2,3,4)/q+3;/p-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Poland Ferric phosphate (Final addendum to Renewal Assessment Report) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ferric phosphate 29Jan2015 2015 doi:10.2903/j.efsa.2015.3973
+Ferric phosphate 233-149-7 10045-86-0 single chemical entity Component is identical to the substance Ferric phosphate 233-149-7 10045-86-0 iron(3+);phosphate Not in list FePO4 [O-]P(=O)([O-])[O-].[Fe+3] InChI=1S/Fe.H3O4P/c;1-5(2,3)4/h;(H3,1,2,3,4)/q+3;/p-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Poland Ferric phosphate (Final addendum to Renewal Assessment Report) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ferric phosphate 29Jan2015 2015 doi:10.2903/j.efsa.2015.3973
+Ferric phosphate 233-149-7 10045-86-0 single chemical entity Component is identical to the substance Ferric phosphate 233-149-7 10045-86-0 iron(3+);phosphate Not in list FePO4 [O-]P(=O)([O-])[O-].[Fe+3] InChI=1S/Fe.H3O4P/c;1-5(2,3)4/h;(H3,1,2,3,4)/q+3;/p-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Poland Ferric phosphate (Final addendum to Renewal Assessment Report) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ferric phosphate 29Jan2015 2015 doi:10.2903/j.efsa.2015.3973
+Ferric phosphate 233-149-7 10045-86-0 single chemical entity Component is identical to the substance Ferric phosphate 233-149-7 10045-86-0 iron(3+);phosphate Not in list FePO4 [O-]P(=O)([O-])[O-].[Fe+3] InChI=1S/Fe.H3O4P/c;1-5(2,3)4/h;(H3,1,2,3,4)/q+3;/p-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Poland Ferric phosphate (Final addendum to Renewal Assessment Report) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ferric phosphate 29Jan2015 2015 doi:10.2903/j.efsa.2015.3973
+Ferric phosphate 233-149-7 10045-86-0 single chemical entity Component is identical to the substance Ferric phosphate 233-149-7 10045-86-0 iron(3+);phosphate Not in list FePO4 [O-]P(=O)([O-])[O-].[Fe+3] InChI=1S/Fe.H3O4P/c;1-5(2,3)4/h;(H3,1,2,3,4)/q+3;/p-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Poland Ferric phosphate (Final addendum to Renewal Assessment Report) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ferric phosphate 29Jan2015 2015 doi:10.2903/j.efsa.2015.3973
+Ferric phosphate 233-149-7 10045-86-0 single chemical entity Component is identical to the substance Ferric phosphate 233-149-7 10045-86-0 iron(3+);phosphate Not in list FePO4 [O-]P(=O)([O-])[O-].[Fe+3] InChI=1S/Fe.H3O4P/c;1-5(2,3)4/h;(H3,1,2,3,4)/q+3;/p-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Poland Ferric phosphate (Final addendum to Renewal Assessment Report) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ferric phosphate 29Jan2015 2015 doi:10.2903/j.efsa.2015.3973
+Ferric phosphate 233-149-7 10045-86-0 single chemical entity Component is identical to the substance Ferric phosphate 233-149-7 10045-86-0 iron(3+);phosphate Not in list FePO4 [O-]P(=O)([O-])[O-].[Fe+3] InChI=1S/Fe.H3O4P/c;1-5(2,3)4/h;(H3,1,2,3,4)/q+3;/p-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Poland Ferric phosphate (Final addendum to Renewal Assessment Report) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ferric phosphate 29Jan2015 2015 doi:10.2903/j.efsa.2015.3973
+Ferric phosphate 233-149-7 10045-86-0 single chemical entity Component is identical to the substance Ferric phosphate 233-149-7 10045-86-0 iron(3+);phosphate Not in list FePO4 [O-]P(=O)([O-])[O-].[Fe+3] InChI=1S/Fe.H3O4P/c;1-5(2,3)4/h;(H3,1,2,3,4)/q+3;/p-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Poland Ferric phosphate (Final addendum to Renewal Assessment Report) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ferric phosphate 29Jan2015 2015 doi:10.2903/j.efsa.2015.3973
+Ferric phosphate 233-149-7 10045-86-0 single chemical entity Component is identical to the substance Ferric phosphate 233-149-7 10045-86-0 iron(3+);phosphate Not in list FePO4 [O-]P(=O)([O-])[O-].[Fe+3] InChI=1S/Fe.H3O4P/c;1-5(2,3)4/h;(H3,1,2,3,4)/q+3;/p-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Poland Ferric phosphate (Final addendum to Renewal Assessment Report) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ferric phosphate 29Jan2015 2015 doi:10.2903/j.efsa.2015.3973
+Ferric phosphate 233-149-7 10045-86-0 single chemical entity Component is identical to the substance Ferric phosphate 233-149-7 10045-86-0 iron(3+);phosphate Not in list FePO4 [O-]P(=O)([O-])[O-].[Fe+3] InChI=1S/Fe.H3O4P/c;1-5(2,3)4/h;(H3,1,2,3,4)/q+3;/p-3 inorganic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Poland Ferric phosphate (Final addendum to Renewal Assessment Report) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ferric phosphate 29Jan2015 2015 doi:10.2903/j.efsa.2015.3973
+Ferric phosphate 233-149-7 10045-86-0 single chemical entity Component is identical to the substance Ferric phosphate 233-149-7 10045-86-0 iron(3+);phosphate Not in list FePO4 [O-]P(=O)([O-])[O-].[Fe+3] InChI=1S/Fe.H3O4P/c;1-5(2,3)4/h;(H3,1,2,3,4)/q+3;/p-3 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 48.0000000000 h yes not applicable Negative no evidence RMS: Germany - CoRMS: Poland Ferric phosphate (Final addendum to Renewal Assessment Report) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ferric phosphate 29Jan2015 2015 doi:10.2903/j.efsa.2015.3973
+Ferric phosphate 233-149-7 10045-86-0 single chemical entity Component is identical to the substance Ferric phosphate 233-149-7 10045-86-0 iron(3+);phosphate Not in list FePO4 [O-]P(=O)([O-])[O-].[Fe+3] InChI=1S/Fe.H3O4P/c;1-5(2,3)4/h;(H3,1,2,3,4)/q+3;/p-3 inorganic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 24.0000000000 h yes not applicable Negative no evidence RMS: Germany - CoRMS: Poland Ferric phosphate (Final addendum to Renewal Assessment Report) 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance ferric phosphate 29Jan2015 2015 doi:10.2903/j.efsa.2015.3973
+Sedaxane 874967-67-6 mixture or formulation Component is part of a mixture or forumlation Sedaxane 874967-67-6 N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide Not in list C18H19F2N3O FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1 InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle without Negative RMS: France Sedaxane 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane 30Jan2013 2013 doi:10.2903/j.efsa.2013.3057
+Sedaxane 874967-67-6 mixture or formulation Component is part of a mixture or forumlation Sedaxane 874967-67-6 N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide Not in list C18H19F2N3O FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1 InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle without Negative RMS: France Sedaxane 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane 30Jan2013 2013 doi:10.2903/j.efsa.2013.3057
+Sedaxane 874967-67-6 mixture or formulation Component is part of a mixture or forumlation Sedaxane 874967-67-6 N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide Not in list C18H19F2N3O FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1 InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle with Negative RMS: France Sedaxane 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane 30Jan2013 2013 doi:10.2903/j.efsa.2013.3057
+Sedaxane 874967-67-6 mixture or formulation Component is part of a mixture or forumlation Sedaxane 874967-67-6 N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide Not in list C18H19F2N3O FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1 InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle with Negative RMS: France Sedaxane 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane 30Jan2013 2013 doi:10.2903/j.efsa.2013.3057
+Sedaxane 874967-67-6 mixture or formulation Component is part of a mixture or forumlation Sedaxane 874967-67-6 N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide Not in list C18H19F2N3O FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1 InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Sedaxane 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane 30Jan2013 2013 doi:10.2903/j.efsa.2013.3057
+Sedaxane 874967-67-6 mixture or formulation Component is part of a mixture or forumlation Sedaxane 874967-67-6 N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide Not in list C18H19F2N3O FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1 InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Sedaxane 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane 30Jan2013 2013 doi:10.2903/j.efsa.2013.3057
+Sedaxane 874967-67-6 mixture or formulation Component is part of a mixture or forumlation Sedaxane 874967-67-6 N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide Not in list C18H19F2N3O FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1 InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Sedaxane 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane 30Jan2013 2013 doi:10.2903/j.efsa.2013.3057
+Sedaxane 874967-67-6 mixture or formulation Component is part of a mixture or forumlation Sedaxane 874967-67-6 N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide Not in list C18H19F2N3O FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1 InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Sedaxane 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane 30Jan2013 2013 doi:10.2903/j.efsa.2013.3057
+Sedaxane 874967-67-6 mixture or formulation Component is part of a mixture or forumlation Sedaxane 874967-67-6 N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide Not in list C18H19F2N3O FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1 InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Sedaxane 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane 30Jan2013 2013 doi:10.2903/j.efsa.2013.3057
+Sedaxane 874967-67-6 mixture or formulation Component is part of a mixture or forumlation Sedaxane 874967-67-6 N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide Not in list C18H19F2N3O FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1 InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Sedaxane 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane 30Jan2013 2013 doi:10.2903/j.efsa.2013.3057
+Sedaxane 874967-67-6 mixture or formulation Component is part of a mixture or forumlation Sedaxane 874967-67-6 N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide Not in list C18H19F2N3O FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1 InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Sedaxane 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane 30Jan2013 2013 doi:10.2903/j.efsa.2013.3057
+Sedaxane 874967-67-6 mixture or formulation Component is part of a mixture or forumlation Sedaxane 874967-67-6 N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide Not in list C18H19F2N3O FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1 InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Sedaxane 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane 30Jan2013 2013 doi:10.2903/j.efsa.2013.3057
+Sedaxane 874967-67-6 mixture or formulation Component is part of a mixture or forumlation Sedaxane 874967-67-6 N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide Not in list C18H19F2N3O FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1 InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: France Sedaxane 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane 30Jan2013 2013 doi:10.2903/j.efsa.2013.3057
+Sedaxane 874967-67-6 mixture or formulation Component is part of a mixture or forumlation Sedaxane 874967-67-6 N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide Not in list C18H19F2N3O FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1 InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: France Sedaxane 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane 30Jan2013 2013 doi:10.2903/j.efsa.2013.3057
+Sedaxane 874967-67-6 mixture or formulation Component is part of a mixture or forumlation Sedaxane 874967-67-6 N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide Not in list C18H19F2N3O FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1 InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Ambiguous small colonies RMS: France Sedaxane 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane 30Jan2013 2013 doi:10.2903/j.efsa.2013.3057
+Sedaxane 874967-67-6 mixture or formulation Component is part of a mixture or forumlation Sedaxane 874967-67-6 N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide Not in list C18H19F2N3O FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1 InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Ambiguous small colonies RMS: France Sedaxane 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane 30Jan2013 2013 doi:10.2903/j.efsa.2013.3057
+Sedaxane 874967-67-6 mixture or formulation Component is part of a mixture or forumlation Sedaxane 874967-67-6 N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide Not in list C18H19F2N3O FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1 InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Ambiguous large colonies RMS: France Sedaxane 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane 30Jan2013 2013 doi:10.2903/j.efsa.2013.3057
+Sedaxane 874967-67-6 mixture or formulation Component is part of a mixture or forumlation Sedaxane 874967-67-6 N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide Not in list C18H19F2N3O FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1 InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Ambiguous large colonies RMS: France Sedaxane 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane 30Jan2013 2013 doi:10.2903/j.efsa.2013.3057
+Sedaxane 874967-67-6 mixture or formulation Component is part of a mixture or forumlation Sedaxane 874967-67-6 N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide Not in list C18H19F2N3O FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1 InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 12 Male/Female oral: unspecified 48.0000000000 h yes not applicable Negative no evidence RMS: France Sedaxane 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane 30Jan2013 2013 doi:10.2903/j.efsa.2013.3057
+Sedaxane 874967-67-6 mixture or formulation Component is part of a mixture or forumlation Sedaxane 874967-67-6 N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide Not in list C18H19F2N3O FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1 InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 12 Male/Female oral: unspecified 24.0000000000 h yes not applicable Negative no evidence RMS: France Sedaxane 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane 30Jan2013 2013 doi:10.2903/j.efsa.2013.3057
+Sedaxane 874967-67-6 mixture or formulation Component is part of a mixture or forumlation Sedaxane 874967-67-6 N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide Not in list C18H19F2N3O FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1 InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24) organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Sprague-Dawley 4 Male oral: unspecified 16.0000000000 h yes not applicable Ambiguous RMS: France Sedaxane 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane 30Jan2013 2013 doi:10.2903/j.efsa.2013.3057
+Sedaxane 874967-67-6 mixture or formulation Component is part of a mixture or forumlation Sedaxane 874967-67-6 N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide Not in list C18H19F2N3O FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1 InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24) organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Wistar 4 Male/Female oral: gavage 16.0000000000 h yes, concurrent vehicle not applicable Negative RMS: France Sedaxane 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane 30Jan2013 2013 doi:10.2903/j.efsa.2013.3057
+Sedaxane 874967-67-6 mixture or formulation Component is part of a mixture or forumlation Sedaxane 874967-67-6 N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide Not in list C18H19F2N3O FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1 InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24) organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Wistar 4 Male/Female oral: gavage 4.0000000000 h yes, concurrent vehicle not applicable Negative RMS: France Sedaxane 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane 30Jan2013 2013 doi:10.2903/j.efsa.2013.3057
+Sedaxane 874967-67-6 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C5H4F2N2O2 FC(F)c1nncc1C(=O)O InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Sedaxane 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane 30Jan2013 2013 doi:10.2903/j.efsa.2013.3057
+Sedaxane 874967-67-6 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C5H4F2N2O2 FC(F)c1nncc1C(=O)O InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Sedaxane 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane 30Jan2013 2013 doi:10.2903/j.efsa.2013.3057
+Sedaxane 874967-67-6 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C5H4F2N2O2 FC(F)c1nncc1C(=O)O InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Sedaxane 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane 30Jan2013 2013 doi:10.2903/j.efsa.2013.3057
+Sedaxane 874967-67-6 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C5H4F2N2O2 FC(F)c1nncc1C(=O)O InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle without Negative RMS: France Sedaxane 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane 30Jan2013 2013 doi:10.2903/j.efsa.2013.3057
+Sedaxane 874967-67-6 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C5H4F2N2O2 FC(F)c1nncc1C(=O)O InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle with Negative RMS: France Sedaxane 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane 30Jan2013 2013 doi:10.2903/j.efsa.2013.3057
+Sedaxane 874967-67-6 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C5H4F2N2O2 FC(F)c1nncc1C(=O)O InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Sedaxane 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane 30Jan2013 2013 doi:10.2903/j.efsa.2013.3057
+Sedaxane 874967-67-6 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C5H4F2N2O2 FC(F)c1nncc1C(=O)O InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle without Negative RMS: France Sedaxane 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane 30Jan2013 2013 doi:10.2903/j.efsa.2013.3057
+Sedaxane 874967-67-6 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C5H4F2N2O2 FC(F)c1nncc1C(=O)O InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle with Negative RMS: France Sedaxane 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane 30Jan2013 2013 doi:10.2903/j.efsa.2013.3057
+Sedaxane 874967-67-6 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C5H4F2N2O2 FC(F)c1nncc1C(=O)O InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Sedaxane 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane 30Jan2013 2013 doi:10.2903/j.efsa.2013.3057
+Sedaxane 874967-67-6 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C5H4F2N2O2 FC(F)c1nncc1C(=O)O InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Sedaxane 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane 30Jan2013 2013 doi:10.2903/j.efsa.2013.3057
+Sedaxane 874967-67-6 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C5H4F2N2O2 FC(F)c1nncc1C(=O)O InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Sedaxane 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane 30Jan2013 2013 doi:10.2903/j.efsa.2013.3057
+Sedaxane 874967-67-6 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C5H4F2N2O2 FC(F)c1nncc1C(=O)O InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Sedaxane 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane 30Jan2013 2013 doi:10.2903/j.efsa.2013.3057
+Sedaxane 874967-67-6 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C5H4F2N2O2 FC(F)c1nncc1C(=O)O InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes without Negative RMS: France Sedaxane 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane 30Jan2013 2013 doi:10.2903/j.efsa.2013.3057
+Sedaxane 874967-67-6 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C5H4F2N2O2 FC(F)c1nncc1C(=O)O InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes with Negative RMS: France Sedaxane 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane 30Jan2013 2013 doi:10.2903/j.efsa.2013.3057
+Sedaxane 874967-67-6 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C5H4F2N2O2 FC(F)c1nncc1C(=O)O InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative small colonies RMS: France Sedaxane 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane 30Jan2013 2013 doi:10.2903/j.efsa.2013.3057
+Sedaxane 874967-67-6 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C5H4F2N2O2 FC(F)c1nncc1C(=O)O InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Negative small colonies RMS: France Sedaxane 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane 30Jan2013 2013 doi:10.2903/j.efsa.2013.3057
+Sedaxane 874967-67-6 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C5H4F2N2O2 FC(F)c1nncc1C(=O)O InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative large colonies RMS: France Sedaxane 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane 30Jan2013 2013 doi:10.2903/j.efsa.2013.3057
+Sedaxane 874967-67-6 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid 3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid Not in list C5H4F2N2O2 FC(F)c1nncc1C(=O)O InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Negative large colonies RMS: France Sedaxane 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane 30Jan2013 2013 doi:10.2903/j.efsa.2013.3057
+Sedaxane 874967-67-6 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid 176969-34-9 3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid Not in list C6H6F2N2O2 CN1C=C(C(=N1)C(F)F)C(=O)O InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Sedaxane 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane 30Jan2013 2013 doi:10.2903/j.efsa.2013.3057
+Sedaxane 874967-67-6 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid 176969-34-9 3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid Not in list C6H6F2N2O2 CN1C=C(C(=N1)C(F)F)C(=O)O InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Sedaxane 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane 30Jan2013 2013 doi:10.2903/j.efsa.2013.3057
+Sedaxane 874967-67-6 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid 176969-34-9 3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid Not in list C6H6F2N2O2 CN1C=C(C(=N1)C(F)F)C(=O)O InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Sedaxane 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane 30Jan2013 2013 doi:10.2903/j.efsa.2013.3057
+Sedaxane 874967-67-6 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid 176969-34-9 3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid Not in list C6H6F2N2O2 CN1C=C(C(=N1)C(F)F)C(=O)O InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Sedaxane 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane 30Jan2013 2013 doi:10.2903/j.efsa.2013.3057
+Sedaxane 874967-67-6 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid 176969-34-9 3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid Not in list C6H6F2N2O2 CN1C=C(C(=N1)C(F)F)C(=O)O InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Sedaxane 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane 30Jan2013 2013 doi:10.2903/j.efsa.2013.3057
+Sedaxane 874967-67-6 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid 176969-34-9 3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid Not in list C6H6F2N2O2 CN1C=C(C(=N1)C(F)F)C(=O)O InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Sedaxane 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane 30Jan2013 2013 doi:10.2903/j.efsa.2013.3057
+Sedaxane 874967-67-6 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid 176969-34-9 3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid Not in list C6H6F2N2O2 CN1C=C(C(=N1)C(F)F)C(=O)O InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Sedaxane 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane 30Jan2013 2013 doi:10.2903/j.efsa.2013.3057
+Sedaxane 874967-67-6 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid 176969-34-9 3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid Not in list C6H6F2N2O2 CN1C=C(C(=N1)C(F)F)C(=O)O InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Sedaxane 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane 30Jan2013 2013 doi:10.2903/j.efsa.2013.3057
+Sedaxane 874967-67-6 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid 176969-34-9 3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid Not in list C6H6F2N2O2 CN1C=C(C(=N1)C(F)F)C(=O)O InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle without Negative RMS: France Sedaxane 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane 30Jan2013 2013 doi:10.2903/j.efsa.2013.3057
+Sedaxane 874967-67-6 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid 176969-34-9 3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid Not in list C6H6F2N2O2 CN1C=C(C(=N1)C(F)F)C(=O)O InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle with Negative RMS: France Sedaxane 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane 30Jan2013 2013 doi:10.2903/j.efsa.2013.3057
+Sedaxane 874967-67-6 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid 176969-34-9 3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid Not in list C6H6F2N2O2 CN1C=C(C(=N1)C(F)F)C(=O)O InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle without Negative RMS: France Sedaxane 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane 30Jan2013 2013 doi:10.2903/j.efsa.2013.3057
+Sedaxane 874967-67-6 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid 176969-34-9 3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid Not in list C6H6F2N2O2 CN1C=C(C(=N1)C(F)F)C(=O)O InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle with Negative RMS: France Sedaxane 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane 30Jan2013 2013 doi:10.2903/j.efsa.2013.3057
+Sedaxane 874967-67-6 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid 176969-34-9 3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid Not in list C6H6F2N2O2 CN1C=C(C(=N1)C(F)F)C(=O)O InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative large colonies RMS: France Sedaxane 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane 30Jan2013 2013 doi:10.2903/j.efsa.2013.3057
+Sedaxane 874967-67-6 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid 176969-34-9 3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid Not in list C6H6F2N2O2 CN1C=C(C(=N1)C(F)F)C(=O)O InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Negative large colonies RMS: France Sedaxane 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane 30Jan2013 2013 doi:10.2903/j.efsa.2013.3057
+Sedaxane 874967-67-6 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid 176969-34-9 3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid Not in list C6H6F2N2O2 CN1C=C(C(=N1)C(F)F)C(=O)O InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative small colonies RMS: France Sedaxane 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane 30Jan2013 2013 doi:10.2903/j.efsa.2013.3057
+Sedaxane 874967-67-6 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid 176969-34-9 3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid Not in list C6H6F2N2O2 CN1C=C(C(=N1)C(F)F)C(=O)O InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Negative small colonies RMS: France Sedaxane 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane 30Jan2013 2013 doi:10.2903/j.efsa.2013.3057
+Sedaxane 874967-67-6 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid 176969-34-9 3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid Not in list C6H6F2N2O2 CN1C=C(C(=N1)C(F)F)C(=O)O InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes without Negative RMS: France Sedaxane 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane 30Jan2013 2013 doi:10.2903/j.efsa.2013.3057
+Sedaxane 874967-67-6 single chemical entity Component is a metabolite of the substance 3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid 176969-34-9 3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid Not in list C6H6F2N2O2 CN1C=C(C(=N1)C(F)F)C(=O)O InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes with Negative RMS: France Sedaxane 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane 30Jan2013 2013 doi:10.2903/j.efsa.2013.3057
+Flutolanil 66332-96-5 single chemical entity Component is identical to the substance Flutolanil 66332-96-5 N-(3-propan-2-yloxyphenyl)-2-(trifluoromethyl)benzamide Flutolanil C17H16F3NO2 CC(C)OC1=CC=CC(=C1)NC(=O)C2=CC=CC=C2C(F)(F)F InChI=1S/C17H16F3NO2/c1-11(2)23-13-7-5-6-12(10-13)21-16(22)14-8-3-4-9-15(14)17(18,19)20/h3-11H,1-2H3,(H,21,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Finland Flutolanil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance flutolanil 28Jul2008 2008 doi:10.2903/j.efsa.2008.126r
+Flutolanil 66332-96-5 single chemical entity Component is identical to the substance Flutolanil 66332-96-5 N-(3-propan-2-yloxyphenyl)-2-(trifluoromethyl)benzamide Flutolanil C17H16F3NO2 CC(C)OC1=CC=CC(=C1)NC(=O)C2=CC=CC=C2C(F)(F)F InChI=1S/C17H16F3NO2/c1-11(2)23-13-7-5-6-12(10-13)21-16(22)14-8-3-4-9-15(14)17(18,19)20/h3-11H,1-2H3,(H,21,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Finland Flutolanil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance flutolanil 28Jul2008 2008 doi:10.2903/j.efsa.2008.126r
+Flutolanil 66332-96-5 single chemical entity Component is identical to the substance Flutolanil 66332-96-5 N-(3-propan-2-yloxyphenyl)-2-(trifluoromethyl)benzamide Flutolanil C17H16F3NO2 CC(C)OC1=CC=CC(=C1)NC(=O)C2=CC=CC=C2C(F)(F)F InChI=1S/C17H16F3NO2/c1-11(2)23-13-7-5-6-12(10-13)21-16(22)14-8-3-4-9-15(14)17(18,19)20/h3-11H,1-2H3,(H,21,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes, concurrent vehicle no data Negative RMS: Finland Flutolanil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance flutolanil 28Jul2008 2008 doi:10.2903/j.efsa.2008.126r
+Flutolanil 66332-96-5 single chemical entity Component is identical to the substance Flutolanil 66332-96-5 N-(3-propan-2-yloxyphenyl)-2-(trifluoromethyl)benzamide Flutolanil C17H16F3NO2 CC(C)OC1=CC=CC(=C1)NC(=O)C2=CC=CC=C2C(F)(F)F InChI=1S/C17H16F3NO2/c1-11(2)23-13-7-5-6-12(10-13)21-16(22)14-8-3-4-9-15(14)17(18,19)20/h3-11H,1-2H3,(H,21,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes, concurrent vehicle no data Negative RMS: Finland Flutolanil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance flutolanil 28Jul2008 2008 doi:10.2903/j.efsa.2008.126r
+Flutolanil 66332-96-5 single chemical entity Component is identical to the substance Flutolanil 66332-96-5 N-(3-propan-2-yloxyphenyl)-2-(trifluoromethyl)benzamide Flutolanil C17H16F3NO2 CC(C)OC1=CC=CC(=C1)NC(=O)C2=CC=CC=C2C(F)(F)F InChI=1S/C17H16F3NO2/c1-11(2)23-13-7-5-6-12(10-13)21-16(22)14-8-3-4-9-15(14)17(18,19)20/h3-11H,1-2H3,(H,21,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Finland Flutolanil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance flutolanil 28Jul2008 2008 doi:10.2903/j.efsa.2008.126r
+Flutolanil 66332-96-5 single chemical entity Component is identical to the substance Flutolanil 66332-96-5 N-(3-propan-2-yloxyphenyl)-2-(trifluoromethyl)benzamide Flutolanil C17H16F3NO2 CC(C)OC1=CC=CC(=C1)NC(=O)C2=CC=CC=C2C(F)(F)F InChI=1S/C17H16F3NO2/c1-11(2)23-13-7-5-6-12(10-13)21-16(22)14-8-3-4-9-15(14)17(18,19)20/h3-11H,1-2H3,(H,21,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Finland Flutolanil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance flutolanil 28Jul2008 2008 doi:10.2903/j.efsa.2008.126r
+Flutolanil 66332-96-5 single chemical entity Component is identical to the substance Flutolanil 66332-96-5 N-(3-propan-2-yloxyphenyl)-2-(trifluoromethyl)benzamide Flutolanil C17H16F3NO2 CC(C)OC1=CC=CC(=C1)NC(=O)C2=CC=CC=C2C(F)(F)F InChI=1S/C17H16F3NO2/c1-11(2)23-13-7-5-6-12(10-13)21-16(22)14-8-3-4-9-15(14)17(18,19)20/h3-11H,1-2H3,(H,21,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Finland Flutolanil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance flutolanil 28Jul2008 2008 doi:10.2903/j.efsa.2008.126r
+Flutolanil 66332-96-5 single chemical entity Component is identical to the substance Flutolanil 66332-96-5 N-(3-propan-2-yloxyphenyl)-2-(trifluoromethyl)benzamide Flutolanil C17H16F3NO2 CC(C)OC1=CC=CC(=C1)NC(=O)C2=CC=CC=C2C(F)(F)F InChI=1S/C17H16F3NO2/c1-11(2)23-13-7-5-6-12(10-13)21-16(22)14-8-3-4-9-15(14)17(18,19)20/h3-11H,1-2H3,(H,21,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Finland Flutolanil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance flutolanil 28Jul2008 2008 doi:10.2903/j.efsa.2008.126r
+Flutolanil 66332-96-5 single chemical entity Component is identical to the substance Flutolanil 66332-96-5 N-(3-propan-2-yloxyphenyl)-2-(trifluoromethyl)benzamide Flutolanil C17H16F3NO2 CC(C)OC1=CC=CC(=C1)NC(=O)C2=CC=CC=C2C(F)(F)F InChI=1S/C17H16F3NO2/c1-11(2)23-13-7-5-6-12(10-13)21-16(22)14-8-3-4-9-15(14)17(18,19)20/h3-11H,1-2H3,(H,21,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Finland Flutolanil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance flutolanil 28Jul2008 2008 doi:10.2903/j.efsa.2008.126r
+Flutolanil 66332-96-5 single chemical entity Component is identical to the substance Flutolanil 66332-96-5 N-(3-propan-2-yloxyphenyl)-2-(trifluoromethyl)benzamide Flutolanil C17H16F3NO2 CC(C)OC1=CC=CC(=C1)NC(=O)C2=CC=CC=C2C(F)(F)F InChI=1S/C17H16F3NO2/c1-11(2)23-13-7-5-6-12(10-13)21-16(22)14-8-3-4-9-15(14)17(18,19)20/h3-11H,1-2H3,(H,21,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Finland Flutolanil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance flutolanil 28Jul2008 2008 doi:10.2903/j.efsa.2008.126r
+Flutolanil 66332-96-5 single chemical entity Component is identical to the substance Flutolanil 66332-96-5 N-(3-propan-2-yloxyphenyl)-2-(trifluoromethyl)benzamide Flutolanil C17H16F3NO2 CC(C)OC1=CC=CC(=C1)NC(=O)C2=CC=CC=C2C(F)(F)F InChI=1S/C17H16F3NO2/c1-11(2)23-13-7-5-6-12(10-13)21-16(22)14-8-3-4-9-15(14)17(18,19)20/h3-11H,1-2H3,(H,21,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Finland Flutolanil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance flutolanil 28Jul2008 2008 doi:10.2903/j.efsa.2008.126r
+Flutolanil 66332-96-5 single chemical entity Component is identical to the substance Flutolanil 66332-96-5 N-(3-propan-2-yloxyphenyl)-2-(trifluoromethyl)benzamide Flutolanil C17H16F3NO2 CC(C)OC1=CC=CC(=C1)NC(=O)C2=CC=CC=C2C(F)(F)F InChI=1S/C17H16F3NO2/c1-11(2)23-13-7-5-6-12(10-13)21-16(22)14-8-3-4-9-15(14)17(18,19)20/h3-11H,1-2H3,(H,21,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Finland Flutolanil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance flutolanil 28Jul2008 2008 doi:10.2903/j.efsa.2008.126r
+Flutolanil 66332-96-5 single chemical entity Component is identical to the substance Flutolanil 66332-96-5 N-(3-propan-2-yloxyphenyl)-2-(trifluoromethyl)benzamide Flutolanil C17H16F3NO2 CC(C)OC1=CC=CC(=C1)NC(=O)C2=CC=CC=C2C(F)(F)F InChI=1S/C17H16F3NO2/c1-11(2)23-13-7-5-6-12(10-13)21-16(22)14-8-3-4-9-15(14)17(18,19)20/h3-11H,1-2H3,(H,21,22) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) Not reported yes, concurrent vehicle without Negative RMS: Finland Flutolanil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance flutolanil 28Jul2008 2008 doi:10.2903/j.efsa.2008.126r
+Flutolanil 66332-96-5 single chemical entity Component is identical to the substance Flutolanil 66332-96-5 N-(3-propan-2-yloxyphenyl)-2-(trifluoromethyl)benzamide Flutolanil C17H16F3NO2 CC(C)OC1=CC=CC(=C1)NC(=O)C2=CC=CC=C2C(F)(F)F InChI=1S/C17H16F3NO2/c1-11(2)23-13-7-5-6-12(10-13)21-16(22)14-8-3-4-9-15(14)17(18,19)20/h3-11H,1-2H3,(H,21,22) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) Not reported yes, concurrent vehicle with Positive RMS: Finland Flutolanil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance flutolanil 28Jul2008 2008 doi:10.2903/j.efsa.2008.126r
+Flutolanil 66332-96-5 single chemical entity Component is identical to the substance Flutolanil 66332-96-5 N-(3-propan-2-yloxyphenyl)-2-(trifluoromethyl)benzamide Flutolanil C17H16F3NO2 CC(C)OC1=CC=CC(=C1)NC(=O)C2=CC=CC=C2C(F)(F)F InChI=1S/C17H16F3NO2/c1-11(2)23-13-7-5-6-12(10-13)21-16(22)14-8-3-4-9-15(14)17(18,19)20/h3-11H,1-2H3,(H,21,22) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Finland Flutolanil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance flutolanil 28Jul2008 2008 doi:10.2903/j.efsa.2008.126r
+Flutolanil 66332-96-5 single chemical entity Component is identical to the substance Flutolanil 66332-96-5 N-(3-propan-2-yloxyphenyl)-2-(trifluoromethyl)benzamide Flutolanil C17H16F3NO2 CC(C)OC1=CC=CC(=C1)NC(=O)C2=CC=CC=C2C(F)(F)F InChI=1S/C17H16F3NO2/c1-11(2)23-13-7-5-6-12(10-13)21-16(22)14-8-3-4-9-15(14)17(18,19)20/h3-11H,1-2H3,(H,21,22) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Finland Flutolanil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance flutolanil 28Jul2008 2008 doi:10.2903/j.efsa.2008.126r
+Flutolanil 66332-96-5 single chemical entity Component is identical to the substance Flutolanil 66332-96-5 N-(3-propan-2-yloxyphenyl)-2-(trifluoromethyl)benzamide Flutolanil C17H16F3NO2 CC(C)OC1=CC=CC(=C1)NC(=O)C2=CC=CC=C2C(F)(F)F InChI=1S/C17H16F3NO2/c1-11(2)23-13-7-5-6-12(10-13)21-16(22)14-8-3-4-9-15(14)17(18,19)20/h3-11H,1-2H3,(H,21,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Finland Flutolanil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance flutolanil 28Jul2008 2008 doi:10.2903/j.efsa.2008.126r
+Flutolanil 66332-96-5 single chemical entity Component is identical to the substance Flutolanil 66332-96-5 N-(3-propan-2-yloxyphenyl)-2-(trifluoromethyl)benzamide Flutolanil C17H16F3NO2 CC(C)OC1=CC=CC(=C1)NC(=O)C2=CC=CC=C2C(F)(F)F InChI=1S/C17H16F3NO2/c1-11(2)23-13-7-5-6-12(10-13)21-16(22)14-8-3-4-9-15(14)17(18,19)20/h3-11H,1-2H3,(H,21,22) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Finland Flutolanil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance flutolanil 28Jul2008 2008 doi:10.2903/j.efsa.2008.126r
+Flutolanil 66332-96-5 single chemical entity Component is identical to the substance Flutolanil 66332-96-5 N-(3-propan-2-yloxyphenyl)-2-(trifluoromethyl)benzamide Flutolanil C17H16F3NO2 CC(C)OC1=CC=CC(=C1)NC(=O)C2=CC=CC=C2C(F)(F)F InChI=1S/C17H16F3NO2/c1-11(2)23-13-7-5-6-12(10-13)21-16(22)14-8-3-4-9-15(14)17(18,19)20/h3-11H,1-2H3,(H,21,22) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes without Negative RMS: Finland Flutolanil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance flutolanil 28Jul2008 2008 doi:10.2903/j.efsa.2008.126r
+Flutolanil 66332-96-5 single chemical entity Component is identical to the substance Flutolanil 66332-96-5 N-(3-propan-2-yloxyphenyl)-2-(trifluoromethyl)benzamide Flutolanil C17H16F3NO2 CC(C)OC1=CC=CC(=C1)NC(=O)C2=CC=CC=C2C(F)(F)F InChI=1S/C17H16F3NO2/c1-11(2)23-13-7-5-6-12(10-13)21-16(22)14-8-3-4-9-15(14)17(18,19)20/h3-11H,1-2H3,(H,21,22) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) BDF1 mouse 12 Male/Female oral: unspecified 48.0000000000 yes not applicable Negative no evidence RMS: Finland Flutolanil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance flutolanil 28Jul2008 2008 doi:10.2903/j.efsa.2008.126r
+Flutolanil 66332-96-5 single chemical entity Component is identical to the substance Flutolanil 66332-96-5 N-(3-propan-2-yloxyphenyl)-2-(trifluoromethyl)benzamide Flutolanil C17H16F3NO2 CC(C)OC1=CC=CC(=C1)NC(=O)C2=CC=CC=C2C(F)(F)F InChI=1S/C17H16F3NO2/c1-11(2)23-13-7-5-6-12(10-13)21-16(22)14-8-3-4-9-15(14)17(18,19)20/h3-11H,1-2H3,(H,21,22) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) BDF1 mouse 12 Male/Female oral: unspecified 12.0000000000 yes not applicable Negative no evidence RMS: Finland Flutolanil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance flutolanil 28Jul2008 2008 doi:10.2903/j.efsa.2008.126r
+Flutolanil 66332-96-5 single chemical entity Component is identical to the substance Flutolanil 66332-96-5 N-(3-propan-2-yloxyphenyl)-2-(trifluoromethyl)benzamide Flutolanil C17H16F3NO2 CC(C)OC1=CC=CC(=C1)NC(=O)C2=CC=CC=C2C(F)(F)F InChI=1S/C17H16F3NO2/c1-11(2)23-13-7-5-6-12(10-13)21-16(22)14-8-3-4-9-15(14)17(18,19)20/h3-11H,1-2H3,(H,21,22) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) BDF1 mouse 12 Male/Female oral: unspecified 72.0000000000 yes not applicable Negative no evidence RMS: Finland Flutolanil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance flutolanil 28Jul2008 2008 doi:10.2903/j.efsa.2008.126r
+Flutolanil 66332-96-5 single chemical entity Component is identical to the substance Flutolanil 66332-96-5 N-(3-propan-2-yloxyphenyl)-2-(trifluoromethyl)benzamide Flutolanil C17H16F3NO2 CC(C)OC1=CC=CC(=C1)NC(=O)C2=CC=CC=C2C(F)(F)F InChI=1S/C17H16F3NO2/c1-11(2)23-13-7-5-6-12(10-13)21-16(22)14-8-3-4-9-15(14)17(18,19)20/h3-11H,1-2H3,(H,21,22) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) BDF1 mouse 12 Male/Female oral: unspecified 24.0000000000 yes not applicable Negative no evidence RMS: Finland Flutolanil 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance flutolanil 28Jul2008 2008 doi:10.2903/j.efsa.2008.126r
+Fluopyram 658066-35-4 single chemical entity Component is identical to the substance Fluopyram 658066-35-4 N-[2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethyl]-2-(trifluoromethyl)benzamide Fluopyram C16H11ClF6N2O C1=CC=C(C(=C1)C(=O)NCCC2=C(C=C(C=N2)C(F)(F)F)Cl)C(F)(F)F InChI=1S/C16H11ClF6N2O/c17-12-7-9(15(18,19)20)8-25-13(12)5-6-24-14(26)10-3-1-2-4-11(10)16(21,22)23/h1-4,7-8H,5-6H2,(H,24,26) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Germany Fluopyram (Final addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram 08Apr2013 2013 doi:10.2903/j.efsa.2013.3052
+Fluopyram 658066-35-4 single chemical entity Component is identical to the substance Fluopyram 658066-35-4 N-[2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethyl]-2-(trifluoromethyl)benzamide Fluopyram C16H11ClF6N2O C1=CC=C(C(=C1)C(=O)NCCC2=C(C=C(C=N2)C(F)(F)F)Cl)C(F)(F)F InChI=1S/C16H11ClF6N2O/c17-12-7-9(15(18,19)20)8-25-13(12)5-6-24-14(26)10-3-1-2-4-11(10)16(21,22)23/h1-4,7-8H,5-6H2,(H,24,26) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Germany Fluopyram (Final addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram 08Apr2013 2013 doi:10.2903/j.efsa.2013.3052
+Fluopyram 658066-35-4 single chemical entity Component is identical to the substance Fluopyram 658066-35-4 N-[2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethyl]-2-(trifluoromethyl)benzamide Fluopyram C16H11ClF6N2O C1=CC=C(C(=C1)C(=O)NCCC2=C(C=C(C=N2)C(F)(F)F)Cl)C(F)(F)F InChI=1S/C16H11ClF6N2O/c17-12-7-9(15(18,19)20)8-25-13(12)5-6-24-14(26)10-3-1-2-4-11(10)16(21,22)23/h1-4,7-8H,5-6H2,(H,24,26) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany Fluopyram (Final addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram 08Apr2013 2013 doi:10.2903/j.efsa.2013.3052
+Fluopyram 658066-35-4 single chemical entity Component is identical to the substance Fluopyram 658066-35-4 N-[2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethyl]-2-(trifluoromethyl)benzamide Fluopyram C16H11ClF6N2O C1=CC=C(C(=C1)C(=O)NCCC2=C(C=C(C=N2)C(F)(F)F)Cl)C(F)(F)F InChI=1S/C16H11ClF6N2O/c17-12-7-9(15(18,19)20)8-25-13(12)5-6-24-14(26)10-3-1-2-4-11(10)16(21,22)23/h1-4,7-8H,5-6H2,(H,24,26) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany Fluopyram (Final addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram 08Apr2013 2013 doi:10.2903/j.efsa.2013.3052
+Fluopyram 658066-35-4 single chemical entity Component is identical to the substance Fluopyram 658066-35-4 N-[2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethyl]-2-(trifluoromethyl)benzamide Fluopyram C16H11ClF6N2O C1=CC=C(C(=C1)C(=O)NCCC2=C(C=C(C=N2)C(F)(F)F)Cl)C(F)(F)F InChI=1S/C16H11ClF6N2O/c17-12-7-9(15(18,19)20)8-25-13(12)5-6-24-14(26)10-3-1-2-4-11(10)16(21,22)23/h1-4,7-8H,5-6H2,(H,24,26) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany Fluopyram (Final addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram 08Apr2013 2013 doi:10.2903/j.efsa.2013.3052
+Fluopyram 658066-35-4 single chemical entity Component is identical to the substance Fluopyram 658066-35-4 N-[2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethyl]-2-(trifluoromethyl)benzamide Fluopyram C16H11ClF6N2O C1=CC=C(C(=C1)C(=O)NCCC2=C(C=C(C=N2)C(F)(F)F)Cl)C(F)(F)F InChI=1S/C16H11ClF6N2O/c17-12-7-9(15(18,19)20)8-25-13(12)5-6-24-14(26)10-3-1-2-4-11(10)16(21,22)23/h1-4,7-8H,5-6H2,(H,24,26) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany Fluopyram (Final addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram 08Apr2013 2013 doi:10.2903/j.efsa.2013.3052
+Fluopyram 658066-35-4 single chemical entity Component is identical to the substance Fluopyram 658066-35-4 N-[2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethyl]-2-(trifluoromethyl)benzamide Fluopyram C16H11ClF6N2O C1=CC=C(C(=C1)C(=O)NCCC2=C(C=C(C=N2)C(F)(F)F)Cl)C(F)(F)F InChI=1S/C16H11ClF6N2O/c17-12-7-9(15(18,19)20)8-25-13(12)5-6-24-14(26)10-3-1-2-4-11(10)16(21,22)23/h1-4,7-8H,5-6H2,(H,24,26) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany Fluopyram (Final addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram 08Apr2013 2013 doi:10.2903/j.efsa.2013.3052
+Fluopyram 658066-35-4 single chemical entity Component is identical to the substance Fluopyram 658066-35-4 N-[2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethyl]-2-(trifluoromethyl)benzamide Fluopyram C16H11ClF6N2O C1=CC=C(C(=C1)C(=O)NCCC2=C(C=C(C=N2)C(F)(F)F)Cl)C(F)(F)F InChI=1S/C16H11ClF6N2O/c17-12-7-9(15(18,19)20)8-25-13(12)5-6-24-14(26)10-3-1-2-4-11(10)16(21,22)23/h1-4,7-8H,5-6H2,(H,24,26) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany Fluopyram (Final addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram 08Apr2013 2013 doi:10.2903/j.efsa.2013.3052
+Fluopyram 658066-35-4 single chemical entity Component is identical to the substance Fluopyram 658066-35-4 N-[2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethyl]-2-(trifluoromethyl)benzamide Fluopyram C16H11ClF6N2O C1=CC=C(C(=C1)C(=O)NCCC2=C(C=C(C=N2)C(F)(F)F)Cl)C(F)(F)F InChI=1S/C16H11ClF6N2O/c17-12-7-9(15(18,19)20)8-25-13(12)5-6-24-14(26)10-3-1-2-4-11(10)16(21,22)23/h1-4,7-8H,5-6H2,(H,24,26) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany Fluopyram (Final addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram 08Apr2013 2013 doi:10.2903/j.efsa.2013.3052
+Fluopyram 658066-35-4 single chemical entity Component is identical to the substance Fluopyram 658066-35-4 N-[2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethyl]-2-(trifluoromethyl)benzamide Fluopyram C16H11ClF6N2O C1=CC=C(C(=C1)C(=O)NCCC2=C(C=C(C=N2)C(F)(F)F)Cl)C(F)(F)F InChI=1S/C16H11ClF6N2O/c17-12-7-9(15(18,19)20)8-25-13(12)5-6-24-14(26)10-3-1-2-4-11(10)16(21,22)23/h1-4,7-8H,5-6H2,(H,24,26) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany Fluopyram (Final addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram 08Apr2013 2013 doi:10.2903/j.efsa.2013.3052
+Fluopyram 658066-35-4 single chemical entity Component is identical to the substance Fluopyram 658066-35-4 N-[2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethyl]-2-(trifluoromethyl)benzamide Fluopyram C16H11ClF6N2O C1=CC=C(C(=C1)C(=O)NCCC2=C(C=C(C=N2)C(F)(F)F)Cl)C(F)(F)F InChI=1S/C16H11ClF6N2O/c17-12-7-9(15(18,19)20)8-25-13(12)5-6-24-14(26)10-3-1-2-4-11(10)16(21,22)23/h1-4,7-8H,5-6H2,(H,24,26) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany Fluopyram (Final addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram 08Apr2013 2013 doi:10.2903/j.efsa.2013.3052
+Fluopyram 658066-35-4 single chemical entity Component is identical to the substance Fluopyram 658066-35-4 N-[2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethyl]-2-(trifluoromethyl)benzamide Fluopyram C16H11ClF6N2O C1=CC=C(C(=C1)C(=O)NCCC2=C(C=C(C=N2)C(F)(F)F)Cl)C(F)(F)F InChI=1S/C16H11ClF6N2O/c17-12-7-9(15(18,19)20)8-25-13(12)5-6-24-14(26)10-3-1-2-4-11(10)16(21,22)23/h1-4,7-8H,5-6H2,(H,24,26) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany Fluopyram (Final addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram 08Apr2013 2013 doi:10.2903/j.efsa.2013.3052
+Fluopyram 658066-35-4 single chemical entity Component is identical to the substance Fluopyram 658066-35-4 N-[2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethyl]-2-(trifluoromethyl)benzamide Fluopyram C16H11ClF6N2O C1=CC=C(C(=C1)C(=O)NCCC2=C(C=C(C=N2)C(F)(F)F)Cl)C(F)(F)F InChI=1S/C16H11ClF6N2O/c17-12-7-9(15(18,19)20)8-25-13(12)5-6-24-14(26)10-3-1-2-4-11(10)16(21,22)23/h1-4,7-8H,5-6H2,(H,24,26) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany Fluopyram (Final addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram 08Apr2013 2013 doi:10.2903/j.efsa.2013.3052
+Fluopyram 658066-35-4 single chemical entity Component is identical to the substance Fluopyram 658066-35-4 N-[2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethyl]-2-(trifluoromethyl)benzamide Fluopyram C16H11ClF6N2O C1=CC=C(C(=C1)C(=O)NCCC2=C(C=C(C=N2)C(F)(F)F)Cl)C(F)(F)F InChI=1S/C16H11ClF6N2O/c17-12-7-9(15(18,19)20)8-25-13(12)5-6-24-14(26)10-3-1-2-4-11(10)16(21,22)23/h1-4,7-8H,5-6H2,(H,24,26) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany Fluopyram (Final addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram 08Apr2013 2013 doi:10.2903/j.efsa.2013.3052
+Fluopyram 658066-35-4 single chemical entity Component is identical to the substance Fluopyram 658066-35-4 N-[2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethyl]-2-(trifluoromethyl)benzamide Fluopyram C16H11ClF6N2O C1=CC=C(C(=C1)C(=O)NCCC2=C(C=C(C=N2)C(F)(F)F)Cl)C(F)(F)F InChI=1S/C16H11ClF6N2O/c17-12-7-9(15(18,19)20)8-25-13(12)5-6-24-14(26)10-3-1-2-4-11(10)16(21,22)23/h1-4,7-8H,5-6H2,(H,24,26) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany Fluopyram (Final addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram 08Apr2013 2013 doi:10.2903/j.efsa.2013.3052
+Fluopyram 658066-35-4 single chemical entity Component is identical to the substance Fluopyram 658066-35-4 N-[2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethyl]-2-(trifluoromethyl)benzamide Fluopyram C16H11ClF6N2O C1=CC=C(C(=C1)C(=O)NCCC2=C(C=C(C=N2)C(F)(F)F)Cl)C(F)(F)F InChI=1S/C16H11ClF6N2O/c17-12-7-9(15(18,19)20)8-25-13(12)5-6-24-14(26)10-3-1-2-4-11(10)16(21,22)23/h1-4,7-8H,5-6H2,(H,24,26) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany Fluopyram (Final addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram 08Apr2013 2013 doi:10.2903/j.efsa.2013.3052
+Fluopyram 658066-35-4 single chemical entity Component is identical to the substance Fluopyram 658066-35-4 N-[2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethyl]-2-(trifluoromethyl)benzamide Fluopyram C16H11ClF6N2O C1=CC=C(C(=C1)C(=O)NCCC2=C(C=C(C=N2)C(F)(F)F)Cl)C(F)(F)F InChI=1S/C16H11ClF6N2O/c17-12-7-9(15(18,19)20)8-25-13(12)5-6-24-14(26)10-3-1-2-4-11(10)16(21,22)23/h1-4,7-8H,5-6H2,(H,24,26) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Germany Fluopyram (Final addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram 08Apr2013 2013 doi:10.2903/j.efsa.2013.3052
+Fluopyram 658066-35-4 single chemical entity Component is identical to the substance Fluopyram 658066-35-4 N-[2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethyl]-2-(trifluoromethyl)benzamide Fluopyram C16H11ClF6N2O C1=CC=C(C(=C1)C(=O)NCCC2=C(C=C(C=N2)C(F)(F)F)Cl)C(F)(F)F InChI=1S/C16H11ClF6N2O/c17-12-7-9(15(18,19)20)8-25-13(12)5-6-24-14(26)10-3-1-2-4-11(10)16(21,22)23/h1-4,7-8H,5-6H2,(H,24,26) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany Fluopyram (Final addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram 08Apr2013 2013 doi:10.2903/j.efsa.2013.3052
+Fluopyram 658066-35-4 single chemical entity Component is identical to the substance Fluopyram 658066-35-4 N-[2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethyl]-2-(trifluoromethyl)benzamide Fluopyram C16H11ClF6N2O C1=CC=C(C(=C1)C(=O)NCCC2=C(C=C(C=N2)C(F)(F)F)Cl)C(F)(F)F InChI=1S/C16H11ClF6N2O/c17-12-7-9(15(18,19)20)8-25-13(12)5-6-24-14(26)10-3-1-2-4-11(10)16(21,22)23/h1-4,7-8H,5-6H2,(H,24,26) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany Fluopyram (Final addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram 08Apr2013 2013 doi:10.2903/j.efsa.2013.3052
+Fluopyram 658066-35-4 single chemical entity Component is identical to the substance Fluopyram 658066-35-4 N-[2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethyl]-2-(trifluoromethyl)benzamide Fluopyram C16H11ClF6N2O C1=CC=C(C(=C1)C(=O)NCCC2=C(C=C(C=N2)C(F)(F)F)Cl)C(F)(F)F InChI=1S/C16H11ClF6N2O/c17-12-7-9(15(18,19)20)8-25-13(12)5-6-24-14(26)10-3-1-2-4-11(10)16(21,22)23/h1-4,7-8H,5-6H2,(H,24,26) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Germany Fluopyram (Final addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram 08Apr2013 2013 doi:10.2903/j.efsa.2013.3052
+Fluopyram 658066-35-4 single chemical entity Component is identical to the substance Fluopyram 658066-35-4 N-[2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethyl]-2-(trifluoromethyl)benzamide Fluopyram C16H11ClF6N2O C1=CC=C(C(=C1)C(=O)NCCC2=C(C=C(C=N2)C(F)(F)F)Cl)C(F)(F)F InChI=1S/C16H11ClF6N2O/c17-12-7-9(15(18,19)20)8-25-13(12)5-6-24-14(26)10-3-1-2-4-11(10)16(21,22)23/h1-4,7-8H,5-6H2,(H,24,26) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: Germany Fluopyram (Final addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram 08Apr2013 2013 doi:10.2903/j.efsa.2013.3052
+Fluopyram 658066-35-4 single chemical entity Component is identical to the substance Fluopyram 658066-35-4 N-[2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethyl]-2-(trifluoromethyl)benzamide Fluopyram C16H11ClF6N2O C1=CC=C(C(=C1)C(=O)NCCC2=C(C=C(C=N2)C(F)(F)F)Cl)C(F)(F)F InChI=1S/C16H11ClF6N2O/c17-12-7-9(15(18,19)20)8-25-13(12)5-6-24-14(26)10-3-1-2-4-11(10)16(21,22)23/h1-4,7-8H,5-6H2,(H,24,26) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Negative RMS: Germany Fluopyram (Final addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram 08Apr2013 2013 doi:10.2903/j.efsa.2013.3052
+Fluopyram 658066-35-4 single chemical entity Component is identical to the substance Fluopyram 658066-35-4 N-[2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethyl]-2-(trifluoromethyl)benzamide Fluopyram C16H11ClF6N2O C1=CC=C(C(=C1)C(=O)NCCC2=C(C=C(C=N2)C(F)(F)F)Cl)C(F)(F)F InChI=1S/C16H11ClF6N2O/c17-12-7-9(15(18,19)20)8-25-13(12)5-6-24-14(26)10-3-1-2-4-11(10)16(21,22)23/h1-4,7-8H,5-6H2,(H,24,26) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: Germany Fluopyram (Final addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram 08Apr2013 2013 doi:10.2903/j.efsa.2013.3052
+Fluopyram 658066-35-4 single chemical entity Component is identical to the substance Fluopyram 658066-35-4 N-[2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethyl]-2-(trifluoromethyl)benzamide Fluopyram C16H11ClF6N2O C1=CC=C(C(=C1)C(=O)NCCC2=C(C=C(C=N2)C(F)(F)F)Cl)C(F)(F)F InChI=1S/C16H11ClF6N2O/c17-12-7-9(15(18,19)20)8-25-13(12)5-6-24-14(26)10-3-1-2-4-11(10)16(21,22)23/h1-4,7-8H,5-6H2,(H,24,26) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Negative RMS: Germany Fluopyram (Final addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram 08Apr2013 2013 doi:10.2903/j.efsa.2013.3052
+Fluopyram 658066-35-4 single chemical entity Component is identical to the substance Fluopyram 658066-35-4 N-[2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethyl]-2-(trifluoromethyl)benzamide Fluopyram C16H11ClF6N2O C1=CC=C(C(=C1)C(=O)NCCC2=C(C=C(C=N2)C(F)(F)F)Cl)C(F)(F)F InChI=1S/C16H11ClF6N2O/c17-12-7-9(15(18,19)20)8-25-13(12)5-6-24-14(26)10-3-1-2-4-11(10)16(21,22)23/h1-4,7-8H,5-6H2,(H,24,26) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 5 Male intraperitoneal 24.0000000000 h yes not applicable Negative direct evidence-cytotoxicity RMS: Germany Fluopyram (Final addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram 08Apr2013 2013 doi:10.2903/j.efsa.2013.3052
+Fluopyram 658066-35-4 single chemical entity Component is a metabolite of the substance 3-chloro-5-(trifluoromethyl)-2-pyridinecarboxylic acid 3-chloro-5-(trifluoromethyl)-2-pyridinecarboxylic acid Not in list C7H3ClF3NO2 Clc1cc(cnc1C(=O)O)C(F)(F)F InChI=1/C7H3ClF3NO2/c8-4-1-3(7(9,10)11)2-12-5(4)6(13)14/h1-2H,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle without Negative RMS: Germany Fluopyram (Final addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram 08Apr2013 2013 doi:10.2903/j.efsa.2013.3052
+Fluopyram 658066-35-4 single chemical entity Component is a metabolite of the substance 3-chloro-5-(trifluoromethyl)-2-pyridinecarboxylic acid 3-chloro-5-(trifluoromethyl)-2-pyridinecarboxylic acid Not in list C7H3ClF3NO2 Clc1cc(cnc1C(=O)O)C(F)(F)F InChI=1/C7H3ClF3NO2/c8-4-1-3(7(9,10)11)2-12-5(4)6(13)14/h1-2H,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle with Negative RMS: Germany Fluopyram (Final addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram 08Apr2013 2013 doi:10.2903/j.efsa.2013.3052
+Fluopyram 658066-35-4 single chemical entity Component is a metabolite of the substance 3-chloro-5-(trifluoromethyl)-2-pyridinecarboxylic acid 3-chloro-5-(trifluoromethyl)-2-pyridinecarboxylic acid Not in list C7H3ClF3NO2 Clc1cc(cnc1C(=O)O)C(F)(F)F InChI=1/C7H3ClF3NO2/c8-4-1-3(7(9,10)11)2-12-5(4)6(13)14/h1-2H,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany Fluopyram (Final addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram 08Apr2013 2013 doi:10.2903/j.efsa.2013.3052
+Fluopyram 658066-35-4 single chemical entity Component is a metabolite of the substance 3-chloro-5-(trifluoromethyl)-2-pyridinecarboxylic acid 3-chloro-5-(trifluoromethyl)-2-pyridinecarboxylic acid Not in list C7H3ClF3NO2 Clc1cc(cnc1C(=O)O)C(F)(F)F InChI=1/C7H3ClF3NO2/c8-4-1-3(7(9,10)11)2-12-5(4)6(13)14/h1-2H,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany Fluopyram (Final addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram 08Apr2013 2013 doi:10.2903/j.efsa.2013.3052
+Fluopyram 658066-35-4 single chemical entity Component is a metabolite of the substance 3-chloro-5-(trifluoromethyl)-2-pyridinecarboxylic acid 3-chloro-5-(trifluoromethyl)-2-pyridinecarboxylic acid Not in list C7H3ClF3NO2 Clc1cc(cnc1C(=O)O)C(F)(F)F InChI=1/C7H3ClF3NO2/c8-4-1-3(7(9,10)11)2-12-5(4)6(13)14/h1-2H,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany Fluopyram (Final addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram 08Apr2013 2013 doi:10.2903/j.efsa.2013.3052
+Fluopyram 658066-35-4 single chemical entity Component is a metabolite of the substance 3-chloro-5-(trifluoromethyl)-2-pyridinecarboxylic acid 3-chloro-5-(trifluoromethyl)-2-pyridinecarboxylic acid Not in list C7H3ClF3NO2 Clc1cc(cnc1C(=O)O)C(F)(F)F InChI=1/C7H3ClF3NO2/c8-4-1-3(7(9,10)11)2-12-5(4)6(13)14/h1-2H,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany Fluopyram (Final addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram 08Apr2013 2013 doi:10.2903/j.efsa.2013.3052
+Fluopyram 658066-35-4 single chemical entity Component is a metabolite of the substance 3-chloro-5-(trifluoromethyl)-2-pyridinecarboxylic acid 3-chloro-5-(trifluoromethyl)-2-pyridinecarboxylic acid Not in list C7H3ClF3NO2 Clc1cc(cnc1C(=O)O)C(F)(F)F InChI=1/C7H3ClF3NO2/c8-4-1-3(7(9,10)11)2-12-5(4)6(13)14/h1-2H,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany Fluopyram (Final addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram 08Apr2013 2013 doi:10.2903/j.efsa.2013.3052
+Fluopyram 658066-35-4 single chemical entity Component is a metabolite of the substance 3-chloro-5-(trifluoromethyl)-2-pyridinecarboxylic acid 3-chloro-5-(trifluoromethyl)-2-pyridinecarboxylic acid Not in list C7H3ClF3NO2 Clc1cc(cnc1C(=O)O)C(F)(F)F InChI=1/C7H3ClF3NO2/c8-4-1-3(7(9,10)11)2-12-5(4)6(13)14/h1-2H,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany Fluopyram (Final addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram 08Apr2013 2013 doi:10.2903/j.efsa.2013.3052
+Fluopyram 658066-35-4 single chemical entity Component is a metabolite of the substance 3-chloro-5-(trifluoromethyl)-2-pyridinecarboxylic acid 3-chloro-5-(trifluoromethyl)-2-pyridinecarboxylic acid Not in list C7H3ClF3NO2 Clc1cc(cnc1C(=O)O)C(F)(F)F InChI=1/C7H3ClF3NO2/c8-4-1-3(7(9,10)11)2-12-5(4)6(13)14/h1-2H,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany Fluopyram (Final addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram 08Apr2013 2013 doi:10.2903/j.efsa.2013.3052
+Fluopyram 658066-35-4 single chemical entity Component is a metabolite of the substance 3-chloro-5-(trifluoromethyl)-2-pyridinecarboxylic acid 3-chloro-5-(trifluoromethyl)-2-pyridinecarboxylic acid Not in list C7H3ClF3NO2 Clc1cc(cnc1C(=O)O)C(F)(F)F InChI=1/C7H3ClF3NO2/c8-4-1-3(7(9,10)11)2-12-5(4)6(13)14/h1-2H,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany Fluopyram (Final addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram 08Apr2013 2013 doi:10.2903/j.efsa.2013.3052
+Fluopyram 658066-35-4 single chemical entity Component is a metabolite of the substance 3-chloro-5-(trifluoromethyl)-2-pyridinecarboxylic acid 3-chloro-5-(trifluoromethyl)-2-pyridinecarboxylic acid Not in list C7H3ClF3NO2 Clc1cc(cnc1C(=O)O)C(F)(F)F InChI=1/C7H3ClF3NO2/c8-4-1-3(7(9,10)11)2-12-5(4)6(13)14/h1-2H,(H,13,14) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes with Negative RMS: Germany Fluopyram (Final addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram 08Apr2013 2013 doi:10.2903/j.efsa.2013.3052
+Fluopyram 658066-35-4 single chemical entity Component is a metabolite of the substance 3-chloro-5-(trifluoromethyl)-2-pyridinecarboxylic acid 3-chloro-5-(trifluoromethyl)-2-pyridinecarboxylic acid Not in list C7H3ClF3NO2 Clc1cc(cnc1C(=O)O)C(F)(F)F InChI=1/C7H3ClF3NO2/c8-4-1-3(7(9,10)11)2-12-5(4)6(13)14/h1-2H,(H,13,14) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes without Negative RMS: Germany Fluopyram (Final addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram 08Apr2013 2013 doi:10.2903/j.efsa.2013.3052
+Fluopyram 658066-35-4 single chemical entity Component is a metabolite of the substance 3-chloro-5-(trifluoromethyl)-2-pyridinecarboxylic acid 3-chloro-5-(trifluoromethyl)-2-pyridinecarboxylic acid Not in list C7H3ClF3NO2 Clc1cc(cnc1C(=O)O)C(F)(F)F InChI=1/C7H3ClF3NO2/c8-4-1-3(7(9,10)11)2-12-5(4)6(13)14/h1-2H,(H,13,14) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: Germany Fluopyram (Final addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram 08Apr2013 2013 doi:10.2903/j.efsa.2013.3052
+Fluopyram 658066-35-4 single chemical entity Component is a metabolite of the substance 3-chloro-5-(trifluoromethyl)-2-pyridinecarboxylic acid 3-chloro-5-(trifluoromethyl)-2-pyridinecarboxylic acid Not in list C7H3ClF3NO2 Clc1cc(cnc1C(=O)O)C(F)(F)F InChI=1/C7H3ClF3NO2/c8-4-1-3(7(9,10)11)2-12-5(4)6(13)14/h1-2H,(H,13,14) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Negative RMS: Germany Fluopyram (Final addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram 08Apr2013 2013 doi:10.2903/j.efsa.2013.3052
+Fluopyram 658066-35-4 single chemical entity Component is a metabolite of the substance 3-(methylsulfinyl)-5-(trifluoromethyl)-2-pyridinecarboxylic acid 3-(methylsulfinyl)-5-(trifluoromethyl)-2-pyridinecarboxylic acid Not in list C8H6F3NO3S O=C(O)c1ncc(cc1S(C)=O)C(F)(F)F InChI=1/C8H6F3NO3S/c1-16(15)5-2-4(8(9,10)11)3-12-6(5)7(13)14/h2-3H,1H3,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Germany Fluopyram (Final addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram 08Apr2013 2013 doi:10.2903/j.efsa.2013.3052
+Fluopyram 658066-35-4 single chemical entity Component is a metabolite of the substance 3-(methylsulfinyl)-5-(trifluoromethyl)-2-pyridinecarboxylic acid 3-(methylsulfinyl)-5-(trifluoromethyl)-2-pyridinecarboxylic acid Not in list C8H6F3NO3S O=C(O)c1ncc(cc1S(C)=O)C(F)(F)F InChI=1/C8H6F3NO3S/c1-16(15)5-2-4(8(9,10)11)3-12-6(5)7(13)14/h2-3H,1H3,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany Fluopyram (Final addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram 08Apr2013 2013 doi:10.2903/j.efsa.2013.3052
+Fluopyram 658066-35-4 single chemical entity Component is a metabolite of the substance 3-(methylsulfinyl)-5-(trifluoromethyl)-2-pyridinecarboxylic acid 3-(methylsulfinyl)-5-(trifluoromethyl)-2-pyridinecarboxylic acid Not in list C8H6F3NO3S O=C(O)c1ncc(cc1S(C)=O)C(F)(F)F InChI=1/C8H6F3NO3S/c1-16(15)5-2-4(8(9,10)11)3-12-6(5)7(13)14/h2-3H,1H3,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany Fluopyram (Final addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram 08Apr2013 2013 doi:10.2903/j.efsa.2013.3052
+Fluopyram 658066-35-4 single chemical entity Component is a metabolite of the substance 3-(methylsulfinyl)-5-(trifluoromethyl)-2-pyridinecarboxylic acid 3-(methylsulfinyl)-5-(trifluoromethyl)-2-pyridinecarboxylic acid Not in list C8H6F3NO3S O=C(O)c1ncc(cc1S(C)=O)C(F)(F)F InChI=1/C8H6F3NO3S/c1-16(15)5-2-4(8(9,10)11)3-12-6(5)7(13)14/h2-3H,1H3,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany Fluopyram (Final addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram 08Apr2013 2013 doi:10.2903/j.efsa.2013.3052
+Fluopyram 658066-35-4 single chemical entity Component is a metabolite of the substance 3-(methylsulfinyl)-5-(trifluoromethyl)-2-pyridinecarboxylic acid 3-(methylsulfinyl)-5-(trifluoromethyl)-2-pyridinecarboxylic acid Not in list C8H6F3NO3S O=C(O)c1ncc(cc1S(C)=O)C(F)(F)F InChI=1/C8H6F3NO3S/c1-16(15)5-2-4(8(9,10)11)3-12-6(5)7(13)14/h2-3H,1H3,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany Fluopyram (Final addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram 08Apr2013 2013 doi:10.2903/j.efsa.2013.3052
+Fluopyram 658066-35-4 single chemical entity Component is a metabolite of the substance 3-(methylsulfinyl)-5-(trifluoromethyl)-2-pyridinecarboxylic acid 3-(methylsulfinyl)-5-(trifluoromethyl)-2-pyridinecarboxylic acid Not in list C8H6F3NO3S O=C(O)c1ncc(cc1S(C)=O)C(F)(F)F InChI=1/C8H6F3NO3S/c1-16(15)5-2-4(8(9,10)11)3-12-6(5)7(13)14/h2-3H,1H3,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany Fluopyram (Final addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram 08Apr2013 2013 doi:10.2903/j.efsa.2013.3052
+Fluopyram 658066-35-4 single chemical entity Component is a metabolite of the substance 3-(methylsulfinyl)-5-(trifluoromethyl)-2-pyridinecarboxylic acid 3-(methylsulfinyl)-5-(trifluoromethyl)-2-pyridinecarboxylic acid Not in list C8H6F3NO3S O=C(O)c1ncc(cc1S(C)=O)C(F)(F)F InChI=1/C8H6F3NO3S/c1-16(15)5-2-4(8(9,10)11)3-12-6(5)7(13)14/h2-3H,1H3,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany Fluopyram (Final addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram 08Apr2013 2013 doi:10.2903/j.efsa.2013.3052
+Fluopyram 658066-35-4 single chemical entity Component is a metabolite of the substance 3-(methylsulfinyl)-5-(trifluoromethyl)-2-pyridinecarboxylic acid 3-(methylsulfinyl)-5-(trifluoromethyl)-2-pyridinecarboxylic acid Not in list C8H6F3NO3S O=C(O)c1ncc(cc1S(C)=O)C(F)(F)F InChI=1/C8H6F3NO3S/c1-16(15)5-2-4(8(9,10)11)3-12-6(5)7(13)14/h2-3H,1H3,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Germany Fluopyram (Final addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram 08Apr2013 2013 doi:10.2903/j.efsa.2013.3052
+Fluopyram 658066-35-4 single chemical entity Component is a metabolite of the substance 3-(methylsulfinyl)-5-(trifluoromethyl)-2-pyridinecarboxylic acid 3-(methylsulfinyl)-5-(trifluoromethyl)-2-pyridinecarboxylic acid Not in list C8H6F3NO3S O=C(O)c1ncc(cc1S(C)=O)C(F)(F)F InChI=1/C8H6F3NO3S/c1-16(15)5-2-4(8(9,10)11)3-12-6(5)7(13)14/h2-3H,1H3,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany Fluopyram (Final addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram 08Apr2013 2013 doi:10.2903/j.efsa.2013.3052
+Fluopyram 658066-35-4 single chemical entity Component is a metabolite of the substance 3-(methylsulfinyl)-5-(trifluoromethyl)-2-pyridinecarboxylic acid 3-(methylsulfinyl)-5-(trifluoromethyl)-2-pyridinecarboxylic acid Not in list C8H6F3NO3S O=C(O)c1ncc(cc1S(C)=O)C(F)(F)F InChI=1/C8H6F3NO3S/c1-16(15)5-2-4(8(9,10)11)3-12-6(5)7(13)14/h2-3H,1H3,(H,13,14) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany Fluopyram (Final addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram 08Apr2013 2013 doi:10.2903/j.efsa.2013.3052
+Fluopyram 658066-35-4 single chemical entity Component is a metabolite of the substance 3-(methylsulfinyl)-5-(trifluoromethyl)-2-pyridinecarboxylic acid 3-(methylsulfinyl)-5-(trifluoromethyl)-2-pyridinecarboxylic acid Not in list C8H6F3NO3S O=C(O)c1ncc(cc1S(C)=O)C(F)(F)F InChI=1/C8H6F3NO3S/c1-16(15)5-2-4(8(9,10)11)3-12-6(5)7(13)14/h2-3H,1H3,(H,13,14) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Germany Fluopyram (Final addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram 08Apr2013 2013 doi:10.2903/j.efsa.2013.3052
+Fluopyram 658066-35-4 single chemical entity Component is a metabolite of the substance 3-(methylsulfinyl)-5-(trifluoromethyl)-2-pyridinecarboxylic acid 3-(methylsulfinyl)-5-(trifluoromethyl)-2-pyridinecarboxylic acid Not in list C8H6F3NO3S O=C(O)c1ncc(cc1S(C)=O)C(F)(F)F InChI=1/C8H6F3NO3S/c1-16(15)5-2-4(8(9,10)11)3-12-6(5)7(13)14/h2-3H,1H3,(H,13,14) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Germany Fluopyram (Final addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram 08Apr2013 2013 doi:10.2903/j.efsa.2013.3052
+Fluopyram 658066-35-4 single chemical entity Component is a metabolite of the substance 3-(methylsulfinyl)-5-(trifluoromethyl)-2-pyridinecarboxylic acid 3-(methylsulfinyl)-5-(trifluoromethyl)-2-pyridinecarboxylic acid Not in list C8H6F3NO3S O=C(O)c1ncc(cc1S(C)=O)C(F)(F)F InChI=1/C8H6F3NO3S/c1-16(15)5-2-4(8(9,10)11)3-12-6(5)7(13)14/h2-3H,1H3,(H,13,14) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Negative RMS: Germany Fluopyram (Final addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram 08Apr2013 2013 doi:10.2903/j.efsa.2013.3052
+Fluopyram 658066-35-4 single chemical entity Component is a metabolite of the substance 3-(methylsulfinyl)-5-(trifluoromethyl)-2-pyridinecarboxylic acid 3-(methylsulfinyl)-5-(trifluoromethyl)-2-pyridinecarboxylic acid Not in list C8H6F3NO3S O=C(O)c1ncc(cc1S(C)=O)C(F)(F)F InChI=1/C8H6F3NO3S/c1-16(15)5-2-4(8(9,10)11)3-12-6(5)7(13)14/h2-3H,1H3,(H,13,14) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: Germany Fluopyram (Final addendum) 2012 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram 08Apr2013 2013 doi:10.2903/j.efsa.2013.3052
+Hexythiazox 78587-05-0 single chemical entity Component is identical to the substance Hexythiazox 78587-05-0 (4S,5S)-5-(4-chlorophenyl)-N-cyclohexyl-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Hexythiazox C17H21ClN2O2S C[C@H]2[C@@H](SC(=O)N2C(=O)NC1CCCCC1)c3ccc(Cl)cc3 InChI=1S/C17H21ClN2O2S/c1-11-15(12-7-9-13(18)10-8-12)23-17(22)20(11)16(21)19-14-5-3-2-4-6-14/h7-11,14-15H,2-6H2,1H3,(H,19,21)/t11-,15+/m0/s1 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is identical to the substance Hexythiazox 78587-05-0 (4S,5S)-5-(4-chlorophenyl)-N-cyclohexyl-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Hexythiazox C17H21ClN2O2S C[C@H]2[C@@H](SC(=O)N2C(=O)NC1CCCCC1)c3ccc(Cl)cc3 InChI=1S/C17H21ClN2O2S/c1-11-15(12-7-9-13(18)10-8-12)23-17(22)20(11)16(21)19-14-5-3-2-4-6-14/h7-11,14-15H,2-6H2,1H3,(H,19,21)/t11-,15+/m0/s1 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is identical to the substance Hexythiazox 78587-05-0 (4S,5S)-5-(4-chlorophenyl)-N-cyclohexyl-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Hexythiazox C17H21ClN2O2S C[C@H]2[C@@H](SC(=O)N2C(=O)NC1CCCCC1)c3ccc(Cl)cc3 InChI=1S/C17H21ClN2O2S/c1-11-15(12-7-9-13(18)10-8-12)23-17(22)20(11)16(21)19-14-5-3-2-4-6-14/h7-11,14-15H,2-6H2,1H3,(H,19,21)/t11-,15+/m0/s1 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is identical to the substance Hexythiazox 78587-05-0 (4S,5S)-5-(4-chlorophenyl)-N-cyclohexyl-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Hexythiazox C17H21ClN2O2S C[C@H]2[C@@H](SC(=O)N2C(=O)NC1CCCCC1)c3ccc(Cl)cc3 InChI=1S/C17H21ClN2O2S/c1-11-15(12-7-9-13(18)10-8-12)23-17(22)20(11)16(21)19-14-5-3-2-4-6-14/h7-11,14-15H,2-6H2,1H3,(H,19,21)/t11-,15+/m0/s1 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is identical to the substance Hexythiazox 78587-05-0 (4S,5S)-5-(4-chlorophenyl)-N-cyclohexyl-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Hexythiazox C17H21ClN2O2S C[C@H]2[C@@H](SC(=O)N2C(=O)NC1CCCCC1)c3ccc(Cl)cc3 InChI=1S/C17H21ClN2O2S/c1-11-15(12-7-9-13(18)10-8-12)23-17(22)20(11)16(21)19-14-5-3-2-4-6-14/h7-11,14-15H,2-6H2,1H3,(H,19,21)/t11-,15+/m0/s1 organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes, concurrent vehicle no data Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is identical to the substance Hexythiazox 78587-05-0 (4S,5S)-5-(4-chlorophenyl)-N-cyclohexyl-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Hexythiazox C17H21ClN2O2S C[C@H]2[C@@H](SC(=O)N2C(=O)NC1CCCCC1)c3ccc(Cl)cc3 InChI=1S/C17H21ClN2O2S/c1-11-15(12-7-9-13(18)10-8-12)23-17(22)20(11)16(21)19-14-5-3-2-4-6-14/h7-11,14-15H,2-6H2,1H3,(H,19,21)/t11-,15+/m0/s1 organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes, concurrent vehicle no data Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is identical to the substance Hexythiazox 78587-05-0 (4S,5S)-5-(4-chlorophenyl)-N-cyclohexyl-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Hexythiazox C17H21ClN2O2S C[C@H]2[C@@H](SC(=O)N2C(=O)NC1CCCCC1)c3ccc(Cl)cc3 InChI=1S/C17H21ClN2O2S/c1-11-15(12-7-9-13(18)10-8-12)23-17(22)20(11)16(21)19-14-5-3-2-4-6-14/h7-11,14-15H,2-6H2,1H3,(H,19,21)/t11-,15+/m0/s1 organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is identical to the substance Hexythiazox 78587-05-0 (4S,5S)-5-(4-chlorophenyl)-N-cyclohexyl-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Hexythiazox C17H21ClN2O2S C[C@H]2[C@@H](SC(=O)N2C(=O)NC1CCCCC1)c3ccc(Cl)cc3 InChI=1S/C17H21ClN2O2S/c1-11-15(12-7-9-13(18)10-8-12)23-17(22)20(11)16(21)19-14-5-3-2-4-6-14/h7-11,14-15H,2-6H2,1H3,(H,19,21)/t11-,15+/m0/s1 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) ICR 10 Male/Female intraperitoneal 24.0000000000 h yes not applicable Negative direct evidence-cytotoxicity RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is identical to the substance Hexythiazox 78587-05-0 (4S,5S)-5-(4-chlorophenyl)-N-cyclohexyl-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Hexythiazox C17H21ClN2O2S C[C@H]2[C@@H](SC(=O)N2C(=O)NC1CCCCC1)c3ccc(Cl)cc3 InChI=1S/C17H21ClN2O2S/c1-11-15(12-7-9-13(18)10-8-12)23-17(22)20(11)16(21)19-14-5-3-2-4-6-14/h7-11,14-15H,2-6H2,1H3,(H,19,21)/t11-,15+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Finland Hexythiazox (Addendum 1) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is identical to the substance Hexythiazox 78587-05-0 (4S,5S)-5-(4-chlorophenyl)-N-cyclohexyl-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Hexythiazox C17H21ClN2O2S C[C@H]2[C@@H](SC(=O)N2C(=O)NC1CCCCC1)c3ccc(Cl)cc3 InChI=1S/C17H21ClN2O2S/c1-11-15(12-7-9-13(18)10-8-12)23-17(22)20(11)16(21)19-14-5-3-2-4-6-14/h7-11,14-15H,2-6H2,1H3,(H,19,21)/t11-,15+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle without Negative RMS: Finland Hexythiazox (Addendum 1) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is identical to the substance Hexythiazox 78587-05-0 (4S,5S)-5-(4-chlorophenyl)-N-cyclohexyl-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Hexythiazox C17H21ClN2O2S C[C@H]2[C@@H](SC(=O)N2C(=O)NC1CCCCC1)c3ccc(Cl)cc3 InChI=1S/C17H21ClN2O2S/c1-11-15(12-7-9-13(18)10-8-12)23-17(22)20(11)16(21)19-14-5-3-2-4-6-14/h7-11,14-15H,2-6H2,1H3,(H,19,21)/t11-,15+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Finland Hexythiazox (Addendum 1) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is identical to the substance Hexythiazox 78587-05-0 (4S,5S)-5-(4-chlorophenyl)-N-cyclohexyl-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Hexythiazox C17H21ClN2O2S C[C@H]2[C@@H](SC(=O)N2C(=O)NC1CCCCC1)c3ccc(Cl)cc3 InChI=1S/C17H21ClN2O2S/c1-11-15(12-7-9-13(18)10-8-12)23-17(22)20(11)16(21)19-14-5-3-2-4-6-14/h7-11,14-15H,2-6H2,1H3,(H,19,21)/t11-,15+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Finland Hexythiazox (Addendum 1) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is identical to the substance Hexythiazox 78587-05-0 (4S,5S)-5-(4-chlorophenyl)-N-cyclohexyl-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Hexythiazox C17H21ClN2O2S C[C@H]2[C@@H](SC(=O)N2C(=O)NC1CCCCC1)c3ccc(Cl)cc3 InChI=1S/C17H21ClN2O2S/c1-11-15(12-7-9-13(18)10-8-12)23-17(22)20(11)16(21)19-14-5-3-2-4-6-14/h7-11,14-15H,2-6H2,1H3,(H,19,21)/t11-,15+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Finland Hexythiazox (Addendum 1) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is identical to the substance Hexythiazox 78587-05-0 (4S,5S)-5-(4-chlorophenyl)-N-cyclohexyl-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Hexythiazox C17H21ClN2O2S C[C@H]2[C@@H](SC(=O)N2C(=O)NC1CCCCC1)c3ccc(Cl)cc3 InChI=1S/C17H21ClN2O2S/c1-11-15(12-7-9-13(18)10-8-12)23-17(22)20(11)16(21)19-14-5-3-2-4-6-14/h7-11,14-15H,2-6H2,1H3,(H,19,21)/t11-,15+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle with Negative RMS: Finland Hexythiazox (Addendum 1) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is identical to the substance Hexythiazox 78587-05-0 (4S,5S)-5-(4-chlorophenyl)-N-cyclohexyl-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Hexythiazox C17H21ClN2O2S C[C@H]2[C@@H](SC(=O)N2C(=O)NC1CCCCC1)c3ccc(Cl)cc3 InChI=1S/C17H21ClN2O2S/c1-11-15(12-7-9-13(18)10-8-12)23-17(22)20(11)16(21)19-14-5-3-2-4-6-14/h7-11,14-15H,2-6H2,1H3,(H,19,21)/t11-,15+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Finland Hexythiazox (Addendum 1) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is identical to the substance Hexythiazox 78587-05-0 (4S,5S)-5-(4-chlorophenyl)-N-cyclohexyl-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Hexythiazox C17H21ClN2O2S C[C@H]2[C@@H](SC(=O)N2C(=O)NC1CCCCC1)c3ccc(Cl)cc3 InChI=1S/C17H21ClN2O2S/c1-11-15(12-7-9-13(18)10-8-12)23-17(22)20(11)16(21)19-14-5-3-2-4-6-14/h7-11,14-15H,2-6H2,1H3,(H,19,21)/t11-,15+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Finland Hexythiazox (Addendum 1) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is identical to the substance Hexythiazox 78587-05-0 (4S,5S)-5-(4-chlorophenyl)-N-cyclohexyl-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Hexythiazox C17H21ClN2O2S C[C@H]2[C@@H](SC(=O)N2C(=O)NC1CCCCC1)c3ccc(Cl)cc3 InChI=1S/C17H21ClN2O2S/c1-11-15(12-7-9-13(18)10-8-12)23-17(22)20(11)16(21)19-14-5-3-2-4-6-14/h7-11,14-15H,2-6H2,1H3,(H,19,21)/t11-,15+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Finland Hexythiazox (Addendum 1) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is identical to the substance Hexythiazox 78587-05-0 (4S,5S)-5-(4-chlorophenyl)-N-cyclohexyl-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Hexythiazox C17H21ClN2O2S C[C@H]2[C@@H](SC(=O)N2C(=O)NC1CCCCC1)c3ccc(Cl)cc3 InChI=1S/C17H21ClN2O2S/c1-11-15(12-7-9-13(18)10-8-12)23-17(22)20(11)16(21)19-14-5-3-2-4-6-14/h7-11,14-15H,2-6H2,1H3,(H,19,21)/t11-,15+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Finland Hexythiazox (Addendum 1) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance 5-(4-chlorophenyl)-4-methyl-2-oxo-N-(3-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide 5-(4-chlorophenyl)-4-methyl-2-oxo-N-(3-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide Not in list C17H19ClN2O3S O=C1CC(CCC1)NC(=O)N3C(=O)SC(c2ccc(Cl)cc2)C3C InChI=1/C17H19ClN2O3S/c1-10-15(11-5-7-12(18)8-6-11)24-17(23)20(10)16(22)19-13-3-2-4-14(21)9-13/h5-8,10,13,15H,2-4,9H2,1H3,(H,19,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance 5-(4-chlorophenyl)-N-(3-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide 5-(4-chlorophenyl)-N-(3-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Not in list C17H21ClN2O3S OC1CCCC(C1)NC(=O)N3C(=O)SC(c2ccc(Cl)cc2)C3C InChI=1/C17H21ClN2O3S/c1-10-15(11-5-7-12(18)8-6-11)24-17(23)20(10)16(22)19-13-3-2-4-14(21)9-13/h5-8,10,13-15,21H,2-4,9H2,1H3,(H,19,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4S,5S)-5-(4-chlorophenyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide (4S,5S)-5-(4-chlorophenyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Not in list C11H11ClN2O2S C[C@H]1[C@@H](SC(=O)N1C(=O)N)c2ccc(Cl)cc2 InChI=1/C11H11ClN2O2S/c1-6-9(7-2-4-8(12)5-3-7)17-11(16)14(6)10(13)15/h2-6,9H,1H3,(H2,13,15)/t6-,9+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4S,5S)-5-(4-chlorophenyl)-N-(cis-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide (4S,5S)-5-(4-chlorophenyl)-N-(cis-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Not in list C17H21ClN2O3S C[C@H]2[C@@H](SC(=O)N2C(=O)N[C@@H]1CC[C@H](O)CC1)c3ccc(Cl)cc3 InChI=1/C17H21ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13-15,21H,6-9H2,1H3,(H,19,22)/t10-,13-,14+,15+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4R,5R)-5-(4-chlorophenyl)-4-methyl-2-oxo-N-(4-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide (4R,5R)-5-(4-chlorophenyl)-4-methyl-2-oxo-N-(4-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide Not in list C17H19ClN2O3S C[C@@H]2[C@H](SC(=O)N2C(=O)NC1CCC(=O)CC1)c3ccc(Cl)cc3 InChI=1/C17H19ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13,15H,6-9H2,1H3,(H,19,22)/t10-,15+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance 5-(4-chlorophenyl)-N-(3-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide 5-(4-chlorophenyl)-N-(3-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Not in list C17H21ClN2O3S OC1CCCC(C1)NC(=O)N3C(=O)SC(c2ccc(Cl)cc2)C3C InChI=1/C17H21ClN2O3S/c1-10-15(11-5-7-12(18)8-6-11)24-17(23)20(10)16(22)19-13-3-2-4-14(21)9-13/h5-8,10,13-15,21H,2-4,9H2,1H3,(H,19,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4S,5S)-5-(4-chlorophenyl)-N-(cis-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide (4S,5S)-5-(4-chlorophenyl)-N-(cis-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Not in list C17H21ClN2O3S C[C@H]2[C@@H](SC(=O)N2C(=O)N[C@@H]1CC[C@H](O)CC1)c3ccc(Cl)cc3 InChI=1/C17H21ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13-15,21H,6-9H2,1H3,(H,19,22)/t10-,13-,14+,15+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance 5-(4-chlorophenyl)-4-methyl-2-oxo-N-(3-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide 5-(4-chlorophenyl)-4-methyl-2-oxo-N-(3-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide Not in list C17H19ClN2O3S O=C1CC(CCC1)NC(=O)N3C(=O)SC(c2ccc(Cl)cc2)C3C InChI=1/C17H19ClN2O3S/c1-10-15(11-5-7-12(18)8-6-11)24-17(23)20(10)16(22)19-13-3-2-4-14(21)9-13/h5-8,10,13,15H,2-4,9H2,1H3,(H,19,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance 5-(4-chlorophenyl)-4-methyl-2-oxo-N-(3-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide 5-(4-chlorophenyl)-4-methyl-2-oxo-N-(3-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide Not in list C17H19ClN2O3S O=C1CC(CCC1)NC(=O)N3C(=O)SC(c2ccc(Cl)cc2)C3C InChI=1/C17H19ClN2O3S/c1-10-15(11-5-7-12(18)8-6-11)24-17(23)20(10)16(22)19-13-3-2-4-14(21)9-13/h5-8,10,13,15H,2-4,9H2,1H3,(H,19,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4S,5S)-5-(4-chlorophenyl)-N-[(1S,2S)-2-hydroxycyclohexyl]-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide (4S,5S)-5-(4-chlorophenyl)-N-[(1S,2S)-2-hydroxycyclohexyl]-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Not in list C17H21ClN2O3S C[C@H]2[C@@H](SC(=O)N2C(=O)N[C@H]1CCCC[C@@H]1O)c3ccc(Cl)cc3 InChI=1/C17H21ClN2O3S/c1-10-15(11-6-8-12(18)9-7-11)24-17(23)20(10)16(22)19-13-4-2-3-5-14(13)21/h6-10,13-15,21H,2-5H2,1H3,(H,19,22)/t10-,13-,14-,15+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4S,5S)-5-(4-chlorophenyl)-N-(cis-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide (4S,5S)-5-(4-chlorophenyl)-N-(cis-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Not in list C17H21ClN2O3S C[C@H]2[C@@H](SC(=O)N2C(=O)N[C@@H]1CC[C@H](O)CC1)c3ccc(Cl)cc3 InChI=1/C17H21ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13-15,21H,6-9H2,1H3,(H,19,22)/t10-,13-,14+,15+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4R,5R)-5-(4-chlorophenyl)-N-(trans-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide (4R,5R)-5-(4-chlorophenyl)-N-(trans-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Not in list C17H21ClN2O3S C[C@@H]2[C@H](SC(=O)N2C(=O)N[C@@H]1CC[C@@H](O)CC1)c3ccc(Cl)cc3 InChI=1/C17H21ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13-15,21H,6-9H2,1H3,(H,19,22)/t10-,13-,14-,15+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4R,5R)-5-(4-chlorophenyl)-N-(trans-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide (4R,5R)-5-(4-chlorophenyl)-N-(trans-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Not in list C17H21ClN2O3S C[C@@H]2[C@H](SC(=O)N2C(=O)N[C@@H]1CC[C@@H](O)CC1)c3ccc(Cl)cc3 InChI=1/C17H21ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13-15,21H,6-9H2,1H3,(H,19,22)/t10-,13-,14-,15+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4S,5S)-5-(4-chlorophenyl)-4-methyl-1,3-thiazolidin-2-one (4S,5S)-5-(4-chlorophenyl)-4-methyl-1,3-thiazolidin-2-one Not in list C10H10ClNOS C[C@@H]2NC(=O)S[C@H]2c1ccc(Cl)cc1 InChI=1/C10H10ClNOS/c1-6-9(14-10(13)12-6)7-2-4-8(11)5-3-7/h2-6,9H,1H3,(H,12,13)/t6-,9+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4R,5R)-5-(4-chlorophenyl)-N-(trans-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide (4R,5R)-5-(4-chlorophenyl)-N-(trans-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Not in list C17H21ClN2O3S C[C@@H]2[C@H](SC(=O)N2C(=O)N[C@@H]1CC[C@@H](O)CC1)c3ccc(Cl)cc3 InChI=1/C17H21ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13-15,21H,6-9H2,1H3,(H,19,22)/t10-,13-,14-,15+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4S,5S)-5-(4-chlorophenyl)-4-methyl-1,3-thiazolidin-2-one (4S,5S)-5-(4-chlorophenyl)-4-methyl-1,3-thiazolidin-2-one Not in list C10H10ClNOS C[C@@H]2NC(=O)S[C@H]2c1ccc(Cl)cc1 InChI=1/C10H10ClNOS/c1-6-9(14-10(13)12-6)7-2-4-8(11)5-3-7/h2-6,9H,1H3,(H,12,13)/t6-,9+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance 5-(4-chlorophenyl)-N-(3-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide 5-(4-chlorophenyl)-N-(3-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Not in list C17H21ClN2O3S OC1CCCC(C1)NC(=O)N3C(=O)SC(c2ccc(Cl)cc2)C3C InChI=1/C17H21ClN2O3S/c1-10-15(11-5-7-12(18)8-6-11)24-17(23)20(10)16(22)19-13-3-2-4-14(21)9-13/h5-8,10,13-15,21H,2-4,9H2,1H3,(H,19,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4S,5S)-5-(4-chlorophenyl)-N-(cis-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide (4S,5S)-5-(4-chlorophenyl)-N-(cis-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Not in list C17H21ClN2O3S C[C@H]2[C@@H](SC(=O)N2C(=O)N[C@@H]1CC[C@H](O)CC1)c3ccc(Cl)cc3 InChI=1/C17H21ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13-15,21H,6-9H2,1H3,(H,19,22)/t10-,13-,14+,15+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance 5-(4-chlorophenyl)-4-methyl-2-oxo-N-(3-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide 5-(4-chlorophenyl)-4-methyl-2-oxo-N-(3-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide Not in list C17H19ClN2O3S O=C1CC(CCC1)NC(=O)N3C(=O)SC(c2ccc(Cl)cc2)C3C InChI=1/C17H19ClN2O3S/c1-10-15(11-5-7-12(18)8-6-11)24-17(23)20(10)16(22)19-13-3-2-4-14(21)9-13/h5-8,10,13,15H,2-4,9H2,1H3,(H,19,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance 5-(4-chlorophenyl)-N-(3-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide 5-(4-chlorophenyl)-N-(3-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Not in list C17H21ClN2O3S OC1CCCC(C1)NC(=O)N3C(=O)SC(c2ccc(Cl)cc2)C3C InChI=1/C17H21ClN2O3S/c1-10-15(11-5-7-12(18)8-6-11)24-17(23)20(10)16(22)19-13-3-2-4-14(21)9-13/h5-8,10,13-15,21H,2-4,9H2,1H3,(H,19,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4R,5R)-5-(4-chlorophenyl)-N-(trans-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide (4R,5R)-5-(4-chlorophenyl)-N-(trans-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Not in list C17H21ClN2O3S C[C@@H]2[C@H](SC(=O)N2C(=O)N[C@@H]1CC[C@@H](O)CC1)c3ccc(Cl)cc3 InChI=1/C17H21ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13-15,21H,6-9H2,1H3,(H,19,22)/t10-,13-,14-,15+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4S,5S)-5-(4-chlorophenyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide (4S,5S)-5-(4-chlorophenyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Not in list C11H11ClN2O2S C[C@H]1[C@@H](SC(=O)N1C(=O)N)c2ccc(Cl)cc2 InChI=1/C11H11ClN2O2S/c1-6-9(7-2-4-8(12)5-3-7)17-11(16)14(6)10(13)15/h2-6,9H,1H3,(H2,13,15)/t6-,9+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance 5-(4-chlorophenyl)-4-methyl-2-oxo-N-(3-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide 5-(4-chlorophenyl)-4-methyl-2-oxo-N-(3-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide Not in list C17H19ClN2O3S O=C1CC(CCC1)NC(=O)N3C(=O)SC(c2ccc(Cl)cc2)C3C InChI=1/C17H19ClN2O3S/c1-10-15(11-5-7-12(18)8-6-11)24-17(23)20(10)16(22)19-13-3-2-4-14(21)9-13/h5-8,10,13,15H,2-4,9H2,1H3,(H,19,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance 5-(4-chlorophenyl)-4-methyl-2-oxo-N-(3-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide 5-(4-chlorophenyl)-4-methyl-2-oxo-N-(3-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide Not in list C17H19ClN2O3S O=C1CC(CCC1)NC(=O)N3C(=O)SC(c2ccc(Cl)cc2)C3C InChI=1/C17H19ClN2O3S/c1-10-15(11-5-7-12(18)8-6-11)24-17(23)20(10)16(22)19-13-3-2-4-14(21)9-13/h5-8,10,13,15H,2-4,9H2,1H3,(H,19,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4S,5S)-5-(4-chlorophenyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide (4S,5S)-5-(4-chlorophenyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Not in list C11H11ClN2O2S C[C@H]1[C@@H](SC(=O)N1C(=O)N)c2ccc(Cl)cc2 InChI=1/C11H11ClN2O2S/c1-6-9(7-2-4-8(12)5-3-7)17-11(16)14(6)10(13)15/h2-6,9H,1H3,(H2,13,15)/t6-,9+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4S,5S)-5-(4-chlorophenyl)-N-(cis-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide (4S,5S)-5-(4-chlorophenyl)-N-(cis-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Not in list C17H21ClN2O3S C[C@H]2[C@@H](SC(=O)N2C(=O)N[C@@H]1CC[C@H](O)CC1)c3ccc(Cl)cc3 InChI=1/C17H21ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13-15,21H,6-9H2,1H3,(H,19,22)/t10-,13-,14+,15+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4S,5S)-5-(4-chlorophenyl)-4-methyl-1,3-thiazolidin-2-one (4S,5S)-5-(4-chlorophenyl)-4-methyl-1,3-thiazolidin-2-one Not in list C10H10ClNOS C[C@@H]2NC(=O)S[C@H]2c1ccc(Cl)cc1 InChI=1/C10H10ClNOS/c1-6-9(14-10(13)12-6)7-2-4-8(11)5-3-7/h2-6,9H,1H3,(H,12,13)/t6-,9+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4S,5S)-5-(4-chlorophenyl)-N-(cis-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide (4S,5S)-5-(4-chlorophenyl)-N-(cis-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Not in list C17H21ClN2O3S C[C@H]2[C@@H](SC(=O)N2C(=O)N[C@@H]1CC[C@H](O)CC1)c3ccc(Cl)cc3 InChI=1/C17H21ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13-15,21H,6-9H2,1H3,(H,19,22)/t10-,13-,14+,15+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance 5-(4-chlorophenyl)-4-methyl-2-oxo-N-(3-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide 5-(4-chlorophenyl)-4-methyl-2-oxo-N-(3-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide Not in list C17H19ClN2O3S O=C1CC(CCC1)NC(=O)N3C(=O)SC(c2ccc(Cl)cc2)C3C InChI=1/C17H19ClN2O3S/c1-10-15(11-5-7-12(18)8-6-11)24-17(23)20(10)16(22)19-13-3-2-4-14(21)9-13/h5-8,10,13,15H,2-4,9H2,1H3,(H,19,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4S,5S)-5-(4-chlorophenyl)-N-(cis-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide (4S,5S)-5-(4-chlorophenyl)-N-(cis-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Not in list C17H21ClN2O3S C[C@H]2[C@@H](SC(=O)N2C(=O)N[C@@H]1CC[C@H](O)CC1)c3ccc(Cl)cc3 InChI=1/C17H21ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13-15,21H,6-9H2,1H3,(H,19,22)/t10-,13-,14+,15+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4S,5S)-5-(4-chlorophenyl)-N-(cis-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide (4S,5S)-5-(4-chlorophenyl)-N-(cis-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Not in list C17H21ClN2O3S C[C@H]2[C@@H](SC(=O)N2C(=O)N[C@@H]1CC[C@H](O)CC1)c3ccc(Cl)cc3 InChI=1/C17H21ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13-15,21H,6-9H2,1H3,(H,19,22)/t10-,13-,14+,15+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance 5-(4-chlorophenyl)-N-(3-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide 5-(4-chlorophenyl)-N-(3-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Not in list C17H21ClN2O3S OC1CCCC(C1)NC(=O)N3C(=O)SC(c2ccc(Cl)cc2)C3C InChI=1/C17H21ClN2O3S/c1-10-15(11-5-7-12(18)8-6-11)24-17(23)20(10)16(22)19-13-3-2-4-14(21)9-13/h5-8,10,13-15,21H,2-4,9H2,1H3,(H,19,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance 5-(4-chlorophenyl)-4-methyl-2-oxo-N-(3-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide 5-(4-chlorophenyl)-4-methyl-2-oxo-N-(3-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide Not in list C17H19ClN2O3S O=C1CC(CCC1)NC(=O)N3C(=O)SC(c2ccc(Cl)cc2)C3C InChI=1/C17H19ClN2O3S/c1-10-15(11-5-7-12(18)8-6-11)24-17(23)20(10)16(22)19-13-3-2-4-14(21)9-13/h5-8,10,13,15H,2-4,9H2,1H3,(H,19,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4S,5S)-5-(4-chlorophenyl)-N-(cis-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide (4S,5S)-5-(4-chlorophenyl)-N-(cis-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Not in list C17H21ClN2O3S C[C@H]2[C@@H](SC(=O)N2C(=O)N[C@@H]1CC[C@H](O)CC1)c3ccc(Cl)cc3 InChI=1/C17H21ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13-15,21H,6-9H2,1H3,(H,19,22)/t10-,13-,14+,15+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4S,5S)-5-(4-chlorophenyl)-4-methyl-1,3-thiazolidin-2-one (4S,5S)-5-(4-chlorophenyl)-4-methyl-1,3-thiazolidin-2-one Not in list C10H10ClNOS C[C@@H]2NC(=O)S[C@H]2c1ccc(Cl)cc1 InChI=1/C10H10ClNOS/c1-6-9(14-10(13)12-6)7-2-4-8(11)5-3-7/h2-6,9H,1H3,(H,12,13)/t6-,9+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4S,5S)-5-(4-chlorophenyl)-N-(cis-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide (4S,5S)-5-(4-chlorophenyl)-N-(cis-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Not in list C17H21ClN2O3S C[C@H]2[C@@H](SC(=O)N2C(=O)N[C@@H]1CC[C@H](O)CC1)c3ccc(Cl)cc3 InChI=1/C17H21ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13-15,21H,6-9H2,1H3,(H,19,22)/t10-,13-,14+,15+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4S,5S)-5-(4-chlorophenyl)-N-(cis-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide (4S,5S)-5-(4-chlorophenyl)-N-(cis-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Not in list C17H21ClN2O3S C[C@H]2[C@@H](SC(=O)N2C(=O)N[C@@H]1CC[C@H](O)CC1)c3ccc(Cl)cc3 InChI=1/C17H21ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13-15,21H,6-9H2,1H3,(H,19,22)/t10-,13-,14+,15+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4S,5S)-5-(4-chlorophenyl)-4-methyl-1,3-thiazolidin-2-one (4S,5S)-5-(4-chlorophenyl)-4-methyl-1,3-thiazolidin-2-one Not in list C10H10ClNOS C[C@@H]2NC(=O)S[C@H]2c1ccc(Cl)cc1 InChI=1/C10H10ClNOS/c1-6-9(14-10(13)12-6)7-2-4-8(11)5-3-7/h2-6,9H,1H3,(H,12,13)/t6-,9+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4S,5S)-5-(4-chlorophenyl)-N-[(1S,2S)-2-hydroxycyclohexyl]-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide (4S,5S)-5-(4-chlorophenyl)-N-[(1S,2S)-2-hydroxycyclohexyl]-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Not in list C17H21ClN2O3S C[C@H]2[C@@H](SC(=O)N2C(=O)N[C@H]1CCCC[C@@H]1O)c3ccc(Cl)cc3 InChI=1/C17H21ClN2O3S/c1-10-15(11-6-8-12(18)9-7-11)24-17(23)20(10)16(22)19-13-4-2-3-5-14(13)21/h6-10,13-15,21H,2-5H2,1H3,(H,19,22)/t10-,13-,14-,15+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance 5-(4-chlorophenyl)-4-methyl-2-oxo-N-(3-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide 5-(4-chlorophenyl)-4-methyl-2-oxo-N-(3-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide Not in list C17H19ClN2O3S O=C1CC(CCC1)NC(=O)N3C(=O)SC(c2ccc(Cl)cc2)C3C InChI=1/C17H19ClN2O3S/c1-10-15(11-5-7-12(18)8-6-11)24-17(23)20(10)16(22)19-13-3-2-4-14(21)9-13/h5-8,10,13,15H,2-4,9H2,1H3,(H,19,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4S,5S)-5-(4-chlorophenyl)-N-[(1S,2S)-2-hydroxycyclohexyl]-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide (4S,5S)-5-(4-chlorophenyl)-N-[(1S,2S)-2-hydroxycyclohexyl]-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Not in list C17H21ClN2O3S C[C@H]2[C@@H](SC(=O)N2C(=O)N[C@H]1CCCC[C@@H]1O)c3ccc(Cl)cc3 InChI=1/C17H21ClN2O3S/c1-10-15(11-6-8-12(18)9-7-11)24-17(23)20(10)16(22)19-13-4-2-3-5-14(13)21/h6-10,13-15,21H,2-5H2,1H3,(H,19,22)/t10-,13-,14-,15+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4S,5S)-5-(4-chlorophenyl)-N-[(1S,2S)-2-hydroxycyclohexyl]-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide (4S,5S)-5-(4-chlorophenyl)-N-[(1S,2S)-2-hydroxycyclohexyl]-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Not in list C17H21ClN2O3S C[C@H]2[C@@H](SC(=O)N2C(=O)N[C@H]1CCCC[C@@H]1O)c3ccc(Cl)cc3 InChI=1/C17H21ClN2O3S/c1-10-15(11-6-8-12(18)9-7-11)24-17(23)20(10)16(22)19-13-4-2-3-5-14(13)21/h6-10,13-15,21H,2-5H2,1H3,(H,19,22)/t10-,13-,14-,15+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4S,5S)-5-(4-chlorophenyl)-4-methyl-1,3-thiazolidin-2-one (4S,5S)-5-(4-chlorophenyl)-4-methyl-1,3-thiazolidin-2-one Not in list C10H10ClNOS C[C@@H]2NC(=O)S[C@H]2c1ccc(Cl)cc1 InChI=1/C10H10ClNOS/c1-6-9(14-10(13)12-6)7-2-4-8(11)5-3-7/h2-6,9H,1H3,(H,12,13)/t6-,9+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4S,5S)-5-(4-chlorophenyl)-N-[(1S,2S)-2-hydroxycyclohexyl]-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide (4S,5S)-5-(4-chlorophenyl)-N-[(1S,2S)-2-hydroxycyclohexyl]-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Not in list C17H21ClN2O3S C[C@H]2[C@@H](SC(=O)N2C(=O)N[C@H]1CCCC[C@@H]1O)c3ccc(Cl)cc3 InChI=1/C17H21ClN2O3S/c1-10-15(11-6-8-12(18)9-7-11)24-17(23)20(10)16(22)19-13-4-2-3-5-14(13)21/h6-10,13-15,21H,2-5H2,1H3,(H,19,22)/t10-,13-,14-,15+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4R,5R)-5-(4-chlorophenyl)-4-methyl-2-oxo-N-(4-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide (4R,5R)-5-(4-chlorophenyl)-4-methyl-2-oxo-N-(4-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide Not in list C17H19ClN2O3S C[C@@H]2[C@H](SC(=O)N2C(=O)NC1CCC(=O)CC1)c3ccc(Cl)cc3 InChI=1/C17H19ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13,15H,6-9H2,1H3,(H,19,22)/t10-,15+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4S,5S)-5-(4-chlorophenyl)-N-[(1S,2S)-2-hydroxycyclohexyl]-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide (4S,5S)-5-(4-chlorophenyl)-N-[(1S,2S)-2-hydroxycyclohexyl]-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Not in list C17H21ClN2O3S C[C@H]2[C@@H](SC(=O)N2C(=O)N[C@H]1CCCC[C@@H]1O)c3ccc(Cl)cc3 InChI=1/C17H21ClN2O3S/c1-10-15(11-6-8-12(18)9-7-11)24-17(23)20(10)16(22)19-13-4-2-3-5-14(13)21/h6-10,13-15,21H,2-5H2,1H3,(H,19,22)/t10-,13-,14-,15+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4R,5R)-5-(4-chlorophenyl)-4-methyl-2-oxo-N-(4-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide (4R,5R)-5-(4-chlorophenyl)-4-methyl-2-oxo-N-(4-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide Not in list C17H19ClN2O3S C[C@@H]2[C@H](SC(=O)N2C(=O)NC1CCC(=O)CC1)c3ccc(Cl)cc3 InChI=1/C17H19ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13,15H,6-9H2,1H3,(H,19,22)/t10-,15+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance 5-(4-chlorophenyl)-N-(3-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide 5-(4-chlorophenyl)-N-(3-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Not in list C17H21ClN2O3S OC1CCCC(C1)NC(=O)N3C(=O)SC(c2ccc(Cl)cc2)C3C InChI=1/C17H21ClN2O3S/c1-10-15(11-5-7-12(18)8-6-11)24-17(23)20(10)16(22)19-13-3-2-4-14(21)9-13/h5-8,10,13-15,21H,2-4,9H2,1H3,(H,19,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4R,5R)-5-(4-chlorophenyl)-4-methyl-2-oxo-N-(4-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide (4R,5R)-5-(4-chlorophenyl)-4-methyl-2-oxo-N-(4-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide Not in list C17H19ClN2O3S C[C@@H]2[C@H](SC(=O)N2C(=O)NC1CCC(=O)CC1)c3ccc(Cl)cc3 InChI=1/C17H19ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13,15H,6-9H2,1H3,(H,19,22)/t10-,15+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance 5-(4-chlorophenyl)-N-(3-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide 5-(4-chlorophenyl)-N-(3-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Not in list C17H21ClN2O3S OC1CCCC(C1)NC(=O)N3C(=O)SC(c2ccc(Cl)cc2)C3C InChI=1/C17H21ClN2O3S/c1-10-15(11-5-7-12(18)8-6-11)24-17(23)20(10)16(22)19-13-3-2-4-14(21)9-13/h5-8,10,13-15,21H,2-4,9H2,1H3,(H,19,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4S,5S)-5-(4-chlorophenyl)-N-[(1S,2S)-2-hydroxycyclohexyl]-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide (4S,5S)-5-(4-chlorophenyl)-N-[(1S,2S)-2-hydroxycyclohexyl]-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Not in list C17H21ClN2O3S C[C@H]2[C@@H](SC(=O)N2C(=O)N[C@H]1CCCC[C@@H]1O)c3ccc(Cl)cc3 InChI=1/C17H21ClN2O3S/c1-10-15(11-6-8-12(18)9-7-11)24-17(23)20(10)16(22)19-13-4-2-3-5-14(13)21/h6-10,13-15,21H,2-5H2,1H3,(H,19,22)/t10-,13-,14-,15+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4R,5R)-5-(4-chlorophenyl)-N-(trans-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide (4R,5R)-5-(4-chlorophenyl)-N-(trans-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Not in list C17H21ClN2O3S C[C@@H]2[C@H](SC(=O)N2C(=O)N[C@@H]1CC[C@@H](O)CC1)c3ccc(Cl)cc3 InChI=1/C17H21ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13-15,21H,6-9H2,1H3,(H,19,22)/t10-,13-,14-,15+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4R,5R)-5-(4-chlorophenyl)-4-methyl-2-oxo-N-(4-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide (4R,5R)-5-(4-chlorophenyl)-4-methyl-2-oxo-N-(4-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide Not in list C17H19ClN2O3S C[C@@H]2[C@H](SC(=O)N2C(=O)NC1CCC(=O)CC1)c3ccc(Cl)cc3 InChI=1/C17H19ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13,15H,6-9H2,1H3,(H,19,22)/t10-,15+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance 5-(4-chlorophenyl)-N-(3-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide 5-(4-chlorophenyl)-N-(3-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Not in list C17H21ClN2O3S OC1CCCC(C1)NC(=O)N3C(=O)SC(c2ccc(Cl)cc2)C3C InChI=1/C17H21ClN2O3S/c1-10-15(11-5-7-12(18)8-6-11)24-17(23)20(10)16(22)19-13-3-2-4-14(21)9-13/h5-8,10,13-15,21H,2-4,9H2,1H3,(H,19,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4S,5S)-5-(4-chlorophenyl)-N-[(1S,2S)-2-hydroxycyclohexyl]-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide (4S,5S)-5-(4-chlorophenyl)-N-[(1S,2S)-2-hydroxycyclohexyl]-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Not in list C17H21ClN2O3S C[C@H]2[C@@H](SC(=O)N2C(=O)N[C@H]1CCCC[C@@H]1O)c3ccc(Cl)cc3 InChI=1/C17H21ClN2O3S/c1-10-15(11-6-8-12(18)9-7-11)24-17(23)20(10)16(22)19-13-4-2-3-5-14(13)21/h6-10,13-15,21H,2-5H2,1H3,(H,19,22)/t10-,13-,14-,15+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4S,5S)-5-(4-chlorophenyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide (4S,5S)-5-(4-chlorophenyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Not in list C11H11ClN2O2S C[C@H]1[C@@H](SC(=O)N1C(=O)N)c2ccc(Cl)cc2 InChI=1/C11H11ClN2O2S/c1-6-9(7-2-4-8(12)5-3-7)17-11(16)14(6)10(13)15/h2-6,9H,1H3,(H2,13,15)/t6-,9+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4S,5S)-5-(4-chlorophenyl)-N-(cis-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide (4S,5S)-5-(4-chlorophenyl)-N-(cis-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Not in list C17H21ClN2O3S C[C@H]2[C@@H](SC(=O)N2C(=O)N[C@@H]1CC[C@H](O)CC1)c3ccc(Cl)cc3 InChI=1/C17H21ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13-15,21H,6-9H2,1H3,(H,19,22)/t10-,13-,14+,15+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4R,5R)-5-(4-chlorophenyl)-4-methyl-2-oxo-N-(4-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide (4R,5R)-5-(4-chlorophenyl)-4-methyl-2-oxo-N-(4-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide Not in list C17H19ClN2O3S C[C@@H]2[C@H](SC(=O)N2C(=O)NC1CCC(=O)CC1)c3ccc(Cl)cc3 InChI=1/C17H19ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13,15H,6-9H2,1H3,(H,19,22)/t10-,15+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4R,5R)-5-(4-chlorophenyl)-4-methyl-2-oxo-N-(4-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide (4R,5R)-5-(4-chlorophenyl)-4-methyl-2-oxo-N-(4-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide Not in list C17H19ClN2O3S C[C@@H]2[C@H](SC(=O)N2C(=O)NC1CCC(=O)CC1)c3ccc(Cl)cc3 InChI=1/C17H19ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13,15H,6-9H2,1H3,(H,19,22)/t10-,15+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4R,5R)-5-(4-chlorophenyl)-N-(trans-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide (4R,5R)-5-(4-chlorophenyl)-N-(trans-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Not in list C17H21ClN2O3S C[C@@H]2[C@H](SC(=O)N2C(=O)N[C@@H]1CC[C@@H](O)CC1)c3ccc(Cl)cc3 InChI=1/C17H21ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13-15,21H,6-9H2,1H3,(H,19,22)/t10-,13-,14-,15+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4S,5S)-5-(4-chlorophenyl)-N-[(1S,2S)-2-hydroxycyclohexyl]-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide (4S,5S)-5-(4-chlorophenyl)-N-[(1S,2S)-2-hydroxycyclohexyl]-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Not in list C17H21ClN2O3S C[C@H]2[C@@H](SC(=O)N2C(=O)N[C@H]1CCCC[C@@H]1O)c3ccc(Cl)cc3 InChI=1/C17H21ClN2O3S/c1-10-15(11-6-8-12(18)9-7-11)24-17(23)20(10)16(22)19-13-4-2-3-5-14(13)21/h6-10,13-15,21H,2-5H2,1H3,(H,19,22)/t10-,13-,14-,15+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4R,5R)-5-(4-chlorophenyl)-N-(trans-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide (4R,5R)-5-(4-chlorophenyl)-N-(trans-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Not in list C17H21ClN2O3S C[C@@H]2[C@H](SC(=O)N2C(=O)N[C@@H]1CC[C@@H](O)CC1)c3ccc(Cl)cc3 InChI=1/C17H21ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13-15,21H,6-9H2,1H3,(H,19,22)/t10-,13-,14-,15+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance 5-(4-chlorophenyl)-N-(3-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide 5-(4-chlorophenyl)-N-(3-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Not in list C17H21ClN2O3S OC1CCCC(C1)NC(=O)N3C(=O)SC(c2ccc(Cl)cc2)C3C InChI=1/C17H21ClN2O3S/c1-10-15(11-5-7-12(18)8-6-11)24-17(23)20(10)16(22)19-13-3-2-4-14(21)9-13/h5-8,10,13-15,21H,2-4,9H2,1H3,(H,19,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4R,5R)-5-(4-chlorophenyl)-N-(trans-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide (4R,5R)-5-(4-chlorophenyl)-N-(trans-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Not in list C17H21ClN2O3S C[C@@H]2[C@H](SC(=O)N2C(=O)N[C@@H]1CC[C@@H](O)CC1)c3ccc(Cl)cc3 InChI=1/C17H21ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13-15,21H,6-9H2,1H3,(H,19,22)/t10-,13-,14-,15+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4S,5S)-5-(4-chlorophenyl)-N-[(1S,2S)-2-hydroxycyclohexyl]-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide (4S,5S)-5-(4-chlorophenyl)-N-[(1S,2S)-2-hydroxycyclohexyl]-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Not in list C17H21ClN2O3S C[C@H]2[C@@H](SC(=O)N2C(=O)N[C@H]1CCCC[C@@H]1O)c3ccc(Cl)cc3 InChI=1/C17H21ClN2O3S/c1-10-15(11-6-8-12(18)9-7-11)24-17(23)20(10)16(22)19-13-4-2-3-5-14(13)21/h6-10,13-15,21H,2-5H2,1H3,(H,19,22)/t10-,13-,14-,15+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4S,5S)-5-(4-chlorophenyl)-4-methyl-1,3-thiazolidin-2-one (4S,5S)-5-(4-chlorophenyl)-4-methyl-1,3-thiazolidin-2-one Not in list C10H10ClNOS C[C@@H]2NC(=O)S[C@H]2c1ccc(Cl)cc1 InChI=1/C10H10ClNOS/c1-6-9(14-10(13)12-6)7-2-4-8(11)5-3-7/h2-6,9H,1H3,(H,12,13)/t6-,9+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4R,5R)-5-(4-chlorophenyl)-4-methyl-2-oxo-N-(4-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide (4R,5R)-5-(4-chlorophenyl)-4-methyl-2-oxo-N-(4-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide Not in list C17H19ClN2O3S C[C@@H]2[C@H](SC(=O)N2C(=O)NC1CCC(=O)CC1)c3ccc(Cl)cc3 InChI=1/C17H19ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13,15H,6-9H2,1H3,(H,19,22)/t10-,15+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance 5-(4-chlorophenyl)-N-(3-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide 5-(4-chlorophenyl)-N-(3-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Not in list C17H21ClN2O3S OC1CCCC(C1)NC(=O)N3C(=O)SC(c2ccc(Cl)cc2)C3C InChI=1/C17H21ClN2O3S/c1-10-15(11-5-7-12(18)8-6-11)24-17(23)20(10)16(22)19-13-3-2-4-14(21)9-13/h5-8,10,13-15,21H,2-4,9H2,1H3,(H,19,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance 5-(4-chlorophenyl)-N-(3-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide 5-(4-chlorophenyl)-N-(3-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Not in list C17H21ClN2O3S OC1CCCC(C1)NC(=O)N3C(=O)SC(c2ccc(Cl)cc2)C3C InChI=1/C17H21ClN2O3S/c1-10-15(11-5-7-12(18)8-6-11)24-17(23)20(10)16(22)19-13-3-2-4-14(21)9-13/h5-8,10,13-15,21H,2-4,9H2,1H3,(H,19,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4S,5S)-5-(4-chlorophenyl)-4-methyl-1,3-thiazolidin-2-one (4S,5S)-5-(4-chlorophenyl)-4-methyl-1,3-thiazolidin-2-one Not in list C10H10ClNOS C[C@@H]2NC(=O)S[C@H]2c1ccc(Cl)cc1 InChI=1/C10H10ClNOS/c1-6-9(14-10(13)12-6)7-2-4-8(11)5-3-7/h2-6,9H,1H3,(H,12,13)/t6-,9+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4R,5R)-5-(4-chlorophenyl)-N-(trans-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide (4R,5R)-5-(4-chlorophenyl)-N-(trans-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Not in list C17H21ClN2O3S C[C@@H]2[C@H](SC(=O)N2C(=O)N[C@@H]1CC[C@@H](O)CC1)c3ccc(Cl)cc3 InChI=1/C17H21ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13-15,21H,6-9H2,1H3,(H,19,22)/t10-,13-,14-,15+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance 5-(4-chlorophenyl)-4-methyl-2-oxo-N-(3-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide 5-(4-chlorophenyl)-4-methyl-2-oxo-N-(3-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide Not in list C17H19ClN2O3S O=C1CC(CCC1)NC(=O)N3C(=O)SC(c2ccc(Cl)cc2)C3C InChI=1/C17H19ClN2O3S/c1-10-15(11-5-7-12(18)8-6-11)24-17(23)20(10)16(22)19-13-3-2-4-14(21)9-13/h5-8,10,13,15H,2-4,9H2,1H3,(H,19,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4R,5R)-5-(4-chlorophenyl)-4-methyl-2-oxo-N-(4-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide (4R,5R)-5-(4-chlorophenyl)-4-methyl-2-oxo-N-(4-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide Not in list C17H19ClN2O3S C[C@@H]2[C@H](SC(=O)N2C(=O)NC1CCC(=O)CC1)c3ccc(Cl)cc3 InChI=1/C17H19ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13,15H,6-9H2,1H3,(H,19,22)/t10-,15+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4R,5R)-5-(4-chlorophenyl)-N-(trans-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide (4R,5R)-5-(4-chlorophenyl)-N-(trans-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Not in list C17H21ClN2O3S C[C@@H]2[C@H](SC(=O)N2C(=O)N[C@@H]1CC[C@@H](O)CC1)c3ccc(Cl)cc3 InChI=1/C17H21ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13-15,21H,6-9H2,1H3,(H,19,22)/t10-,13-,14-,15+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4S,5S)-5-(4-chlorophenyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide (4S,5S)-5-(4-chlorophenyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Not in list C11H11ClN2O2S C[C@H]1[C@@H](SC(=O)N1C(=O)N)c2ccc(Cl)cc2 InChI=1/C11H11ClN2O2S/c1-6-9(7-2-4-8(12)5-3-7)17-11(16)14(6)10(13)15/h2-6,9H,1H3,(H2,13,15)/t6-,9+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance 5-(4-chlorophenyl)-4-methyl-2-oxo-N-(3-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide 5-(4-chlorophenyl)-4-methyl-2-oxo-N-(3-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide Not in list C17H19ClN2O3S O=C1CC(CCC1)NC(=O)N3C(=O)SC(c2ccc(Cl)cc2)C3C InChI=1/C17H19ClN2O3S/c1-10-15(11-5-7-12(18)8-6-11)24-17(23)20(10)16(22)19-13-3-2-4-14(21)9-13/h5-8,10,13,15H,2-4,9H2,1H3,(H,19,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4S,5S)-5-(4-chlorophenyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide (4S,5S)-5-(4-chlorophenyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Not in list C11H11ClN2O2S C[C@H]1[C@@H](SC(=O)N1C(=O)N)c2ccc(Cl)cc2 InChI=1/C11H11ClN2O2S/c1-6-9(7-2-4-8(12)5-3-7)17-11(16)14(6)10(13)15/h2-6,9H,1H3,(H2,13,15)/t6-,9+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4S,5S)-5-(4-chlorophenyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide (4S,5S)-5-(4-chlorophenyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Not in list C11H11ClN2O2S C[C@H]1[C@@H](SC(=O)N1C(=O)N)c2ccc(Cl)cc2 InChI=1/C11H11ClN2O2S/c1-6-9(7-2-4-8(12)5-3-7)17-11(16)14(6)10(13)15/h2-6,9H,1H3,(H2,13,15)/t6-,9+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4R,5R)-5-(4-chlorophenyl)-N-(trans-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide (4R,5R)-5-(4-chlorophenyl)-N-(trans-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Not in list C17H21ClN2O3S C[C@@H]2[C@H](SC(=O)N2C(=O)N[C@@H]1CC[C@@H](O)CC1)c3ccc(Cl)cc3 InChI=1/C17H21ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13-15,21H,6-9H2,1H3,(H,19,22)/t10-,13-,14-,15+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4S,5S)-5-(4-chlorophenyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide (4S,5S)-5-(4-chlorophenyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Not in list C11H11ClN2O2S C[C@H]1[C@@H](SC(=O)N1C(=O)N)c2ccc(Cl)cc2 InChI=1/C11H11ClN2O2S/c1-6-9(7-2-4-8(12)5-3-7)17-11(16)14(6)10(13)15/h2-6,9H,1H3,(H2,13,15)/t6-,9+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4R,5R)-5-(4-chlorophenyl)-4-methyl-2-oxo-N-(4-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide (4R,5R)-5-(4-chlorophenyl)-4-methyl-2-oxo-N-(4-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide Not in list C17H19ClN2O3S C[C@@H]2[C@H](SC(=O)N2C(=O)NC1CCC(=O)CC1)c3ccc(Cl)cc3 InChI=1/C17H19ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13,15H,6-9H2,1H3,(H,19,22)/t10-,15+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4S,5S)-5-(4-chlorophenyl)-4-methyl-1,3-thiazolidin-2-one (4S,5S)-5-(4-chlorophenyl)-4-methyl-1,3-thiazolidin-2-one Not in list C10H10ClNOS C[C@@H]2NC(=O)S[C@H]2c1ccc(Cl)cc1 InChI=1/C10H10ClNOS/c1-6-9(14-10(13)12-6)7-2-4-8(11)5-3-7/h2-6,9H,1H3,(H,12,13)/t6-,9+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4R,5R)-5-(4-chlorophenyl)-4-methyl-2-oxo-N-(4-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide (4R,5R)-5-(4-chlorophenyl)-4-methyl-2-oxo-N-(4-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide Not in list C17H19ClN2O3S C[C@@H]2[C@H](SC(=O)N2C(=O)NC1CCC(=O)CC1)c3ccc(Cl)cc3 InChI=1/C17H19ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13,15H,6-9H2,1H3,(H,19,22)/t10-,15+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance 5-(4-chlorophenyl)-4-methyl-2-oxo-N-(3-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide 5-(4-chlorophenyl)-4-methyl-2-oxo-N-(3-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide Not in list C17H19ClN2O3S O=C1CC(CCC1)NC(=O)N3C(=O)SC(c2ccc(Cl)cc2)C3C InChI=1/C17H19ClN2O3S/c1-10-15(11-5-7-12(18)8-6-11)24-17(23)20(10)16(22)19-13-3-2-4-14(21)9-13/h5-8,10,13,15H,2-4,9H2,1H3,(H,19,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4S,5S)-5-(4-chlorophenyl)-4-methyl-1,3-thiazolidin-2-one (4S,5S)-5-(4-chlorophenyl)-4-methyl-1,3-thiazolidin-2-one Not in list C10H10ClNOS C[C@@H]2NC(=O)S[C@H]2c1ccc(Cl)cc1 InChI=1/C10H10ClNOS/c1-6-9(14-10(13)12-6)7-2-4-8(11)5-3-7/h2-6,9H,1H3,(H,12,13)/t6-,9+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4S,5S)-5-(4-chlorophenyl)-N-[(1S,2S)-2-hydroxycyclohexyl]-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide (4S,5S)-5-(4-chlorophenyl)-N-[(1S,2S)-2-hydroxycyclohexyl]-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Not in list C17H21ClN2O3S C[C@H]2[C@@H](SC(=O)N2C(=O)N[C@H]1CCCC[C@@H]1O)c3ccc(Cl)cc3 InChI=1/C17H21ClN2O3S/c1-10-15(11-6-8-12(18)9-7-11)24-17(23)20(10)16(22)19-13-4-2-3-5-14(13)21/h6-10,13-15,21H,2-5H2,1H3,(H,19,22)/t10-,13-,14-,15+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4S,5S)-5-(4-chlorophenyl)-4-methyl-1,3-thiazolidin-2-one (4S,5S)-5-(4-chlorophenyl)-4-methyl-1,3-thiazolidin-2-one Not in list C10H10ClNOS C[C@@H]2NC(=O)S[C@H]2c1ccc(Cl)cc1 InChI=1/C10H10ClNOS/c1-6-9(14-10(13)12-6)7-2-4-8(11)5-3-7/h2-6,9H,1H3,(H,12,13)/t6-,9+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance 5-(4-chlorophenyl)-N-(3-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide 5-(4-chlorophenyl)-N-(3-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Not in list C17H21ClN2O3S OC1CCCC(C1)NC(=O)N3C(=O)SC(c2ccc(Cl)cc2)C3C InChI=1/C17H21ClN2O3S/c1-10-15(11-5-7-12(18)8-6-11)24-17(23)20(10)16(22)19-13-3-2-4-14(21)9-13/h5-8,10,13-15,21H,2-4,9H2,1H3,(H,19,22) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4S,5S)-5-(4-chlorophenyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide (4S,5S)-5-(4-chlorophenyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Not in list C11H11ClN2O2S C[C@H]1[C@@H](SC(=O)N1C(=O)N)c2ccc(Cl)cc2 InChI=1/C11H11ClN2O2S/c1-6-9(7-2-4-8(12)5-3-7)17-11(16)14(6)10(13)15/h2-6,9H,1H3,(H2,13,15)/t6-,9+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4S,5S)-5-(4-chlorophenyl)-4-methyl-1,3-thiazolidin-2-one (4S,5S)-5-(4-chlorophenyl)-4-methyl-1,3-thiazolidin-2-one Not in list C10H10ClNOS C[C@@H]2NC(=O)S[C@H]2c1ccc(Cl)cc1 InChI=1/C10H10ClNOS/c1-6-9(14-10(13)12-6)7-2-4-8(11)5-3-7/h2-6,9H,1H3,(H,12,13)/t6-,9+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4R,5R)-5-(4-chlorophenyl)-4-methyl-2-oxo-N-(4-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide (4R,5R)-5-(4-chlorophenyl)-4-methyl-2-oxo-N-(4-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide Not in list C17H19ClN2O3S C[C@@H]2[C@H](SC(=O)N2C(=O)NC1CCC(=O)CC1)c3ccc(Cl)cc3 InChI=1/C17H19ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13,15H,6-9H2,1H3,(H,19,22)/t10-,15+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4S,5S)-5-(4-chlorophenyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide (4S,5S)-5-(4-chlorophenyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Not in list C11H11ClN2O2S C[C@H]1[C@@H](SC(=O)N1C(=O)N)c2ccc(Cl)cc2 InChI=1/C11H11ClN2O2S/c1-6-9(7-2-4-8(12)5-3-7)17-11(16)14(6)10(13)15/h2-6,9H,1H3,(H2,13,15)/t6-,9+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4S,5S)-5-(4-chlorophenyl)-N-[(1S,2S)-2-hydroxycyclohexyl]-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide (4S,5S)-5-(4-chlorophenyl)-N-[(1S,2S)-2-hydroxycyclohexyl]-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Not in list C17H21ClN2O3S C[C@H]2[C@@H](SC(=O)N2C(=O)N[C@H]1CCCC[C@@H]1O)c3ccc(Cl)cc3 InChI=1/C17H21ClN2O3S/c1-10-15(11-6-8-12(18)9-7-11)24-17(23)20(10)16(22)19-13-4-2-3-5-14(13)21/h6-10,13-15,21H,2-5H2,1H3,(H,19,22)/t10-,13-,14-,15+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4S,5S)-5-(4-chlorophenyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide (4S,5S)-5-(4-chlorophenyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Not in list C11H11ClN2O2S C[C@H]1[C@@H](SC(=O)N1C(=O)N)c2ccc(Cl)cc2 InChI=1/C11H11ClN2O2S/c1-6-9(7-2-4-8(12)5-3-7)17-11(16)14(6)10(13)15/h2-6,9H,1H3,(H2,13,15)/t6-,9+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4R,5R)-5-(4-chlorophenyl)-N-(trans-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide (4R,5R)-5-(4-chlorophenyl)-N-(trans-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Not in list C17H21ClN2O3S C[C@@H]2[C@H](SC(=O)N2C(=O)N[C@@H]1CC[C@@H](O)CC1)c3ccc(Cl)cc3 InChI=1/C17H21ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13-15,21H,6-9H2,1H3,(H,19,22)/t10-,13-,14-,15+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Hexythiazox 78587-05-0 single chemical entity Component is a metabolite of the substance (4S,5S)-5-(4-chlorophenyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide (4S,5S)-5-(4-chlorophenyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide Not in list C11H11ClN2O2S C[C@H]1[C@@H](SC(=O)N1C(=O)N)c2ccc(Cl)cc2 InChI=1/C11H11ClN2O2S/c1-6-9(7-2-4-8(12)5-3-7)17-11(16)14(6)10(13)15/h2-6,9H,1H3,(H2,13,15)/t6-,9+/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Finland Hexythiazox 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox 14Oct2010 2010 doi:10.2903/j.efsa.2010.1722
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is identical to the substance Fenbuconazole 114369-43-6 4-(4-chlorophenyl)-2-phenyl-2-(1H-1,2,4-triazol-1-ylmethyl)butanenitrile Fenbuconazole C19H17ClN4 ClC1=CC=C(CCC(C#N)(CN3N=CN=C3)C2=CC=CC=C2)C=C1 InChI=1S/C19H17ClN4/c20-18-8-6-16(7-9-18)10-11-19(12-21,13-24-15-22-14-23-24)17-4-2-1-3-5-17/h1-9,14-15H,10-11,13H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is identical to the substance Fenbuconazole 114369-43-6 4-(4-chlorophenyl)-2-phenyl-2-(1H-1,2,4-triazol-1-ylmethyl)butanenitrile Fenbuconazole C19H17ClN4 ClC1=CC=C(CCC(C#N)(CN3N=CN=C3)C2=CC=CC=C2)C=C1 InChI=1S/C19H17ClN4/c20-18-8-6-16(7-9-18)10-11-19(12-21,13-24-15-22-14-23-24)17-4-2-1-3-5-17/h1-9,14-15H,10-11,13H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is identical to the substance Fenbuconazole 114369-43-6 4-(4-chlorophenyl)-2-phenyl-2-(1H-1,2,4-triazol-1-ylmethyl)butanenitrile Fenbuconazole C19H17ClN4 ClC1=CC=C(CCC(C#N)(CN3N=CN=C3)C2=CC=CC=C2)C=C1 InChI=1S/C19H17ClN4/c20-18-8-6-16(7-9-18)10-11-19(12-21,13-24-15-22-14-23-24)17-4-2-1-3-5-17/h1-9,14-15H,10-11,13H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is identical to the substance Fenbuconazole 114369-43-6 4-(4-chlorophenyl)-2-phenyl-2-(1H-1,2,4-triazol-1-ylmethyl)butanenitrile Fenbuconazole C19H17ClN4 ClC1=CC=C(CCC(C#N)(CN3N=CN=C3)C2=CC=CC=C2)C=C1 InChI=1S/C19H17ClN4/c20-18-8-6-16(7-9-18)10-11-19(12-21,13-24-15-22-14-23-24)17-4-2-1-3-5-17/h1-9,14-15H,10-11,13H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is identical to the substance Fenbuconazole 114369-43-6 4-(4-chlorophenyl)-2-phenyl-2-(1H-1,2,4-triazol-1-ylmethyl)butanenitrile Fenbuconazole C19H17ClN4 ClC1=CC=C(CCC(C#N)(CN3N=CN=C3)C2=CC=CC=C2)C=C1 InChI=1S/C19H17ClN4/c20-18-8-6-16(7-9-18)10-11-19(12-21,13-24-15-22-14-23-24)17-4-2-1-3-5-17/h1-9,14-15H,10-11,13H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is identical to the substance Fenbuconazole 114369-43-6 4-(4-chlorophenyl)-2-phenyl-2-(1H-1,2,4-triazol-1-ylmethyl)butanenitrile Fenbuconazole C19H17ClN4 ClC1=CC=C(CCC(C#N)(CN3N=CN=C3)C2=CC=CC=C2)C=C1 InChI=1S/C19H17ClN4/c20-18-8-6-16(7-9-18)10-11-19(12-21,13-24-15-22-14-23-24)17-4-2-1-3-5-17/h1-9,14-15H,10-11,13H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is identical to the substance Fenbuconazole 114369-43-6 4-(4-chlorophenyl)-2-phenyl-2-(1H-1,2,4-triazol-1-ylmethyl)butanenitrile Fenbuconazole C19H17ClN4 ClC1=CC=C(CCC(C#N)(CN3N=CN=C3)C2=CC=CC=C2)C=C1 InChI=1S/C19H17ClN4/c20-18-8-6-16(7-9-18)10-11-19(12-21,13-24-15-22-14-23-24)17-4-2-1-3-5-17/h1-9,14-15H,10-11,13H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is identical to the substance Fenbuconazole 114369-43-6 4-(4-chlorophenyl)-2-phenyl-2-(1H-1,2,4-triazol-1-ylmethyl)butanenitrile Fenbuconazole C19H17ClN4 ClC1=CC=C(CCC(C#N)(CN3N=CN=C3)C2=CC=CC=C2)C=C1 InChI=1S/C19H17ClN4/c20-18-8-6-16(7-9-18)10-11-19(12-21,13-24-15-22-14-23-24)17-4-2-1-3-5-17/h1-9,14-15H,10-11,13H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is identical to the substance Fenbuconazole 114369-43-6 4-(4-chlorophenyl)-2-phenyl-2-(1H-1,2,4-triazol-1-ylmethyl)butanenitrile Fenbuconazole C19H17ClN4 ClC1=CC=C(CCC(C#N)(CN3N=CN=C3)C2=CC=CC=C2)C=C1 InChI=1S/C19H17ClN4/c20-18-8-6-16(7-9-18)10-11-19(12-21,13-24-15-22-14-23-24)17-4-2-1-3-5-17/h1-9,14-15H,10-11,13H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is identical to the substance Fenbuconazole 114369-43-6 4-(4-chlorophenyl)-2-phenyl-2-(1H-1,2,4-triazol-1-ylmethyl)butanenitrile Fenbuconazole C19H17ClN4 ClC1=CC=C(CCC(C#N)(CN3N=CN=C3)C2=CC=CC=C2)C=C1 InChI=1S/C19H17ClN4/c20-18-8-6-16(7-9-18)10-11-19(12-21,13-24-15-22-14-23-24)17-4-2-1-3-5-17/h1-9,14-15H,10-11,13H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is identical to the substance Fenbuconazole 114369-43-6 4-(4-chlorophenyl)-2-phenyl-2-(1H-1,2,4-triazol-1-ylmethyl)butanenitrile Fenbuconazole C19H17ClN4 ClC1=CC=C(CCC(C#N)(CN3N=CN=C3)C2=CC=CC=C2)C=C1 InChI=1S/C19H17ClN4/c20-18-8-6-16(7-9-18)10-11-19(12-21,13-24-15-22-14-23-24)17-4-2-1-3-5-17/h1-9,14-15H,10-11,13H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is identical to the substance Fenbuconazole 114369-43-6 4-(4-chlorophenyl)-2-phenyl-2-(1H-1,2,4-triazol-1-ylmethyl)butanenitrile Fenbuconazole C19H17ClN4 ClC1=CC=C(CCC(C#N)(CN3N=CN=C3)C2=CC=CC=C2)C=C1 InChI=1S/C19H17ClN4/c20-18-8-6-16(7-9-18)10-11-19(12-21,13-24-15-22-14-23-24)17-4-2-1-3-5-17/h1-9,14-15H,10-11,13H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is identical to the substance Fenbuconazole 114369-43-6 4-(4-chlorophenyl)-2-phenyl-2-(1H-1,2,4-triazol-1-ylmethyl)butanenitrile Fenbuconazole C19H17ClN4 ClC1=CC=C(CCC(C#N)(CN3N=CN=C3)C2=CC=CC=C2)C=C1 InChI=1S/C19H17ClN4/c20-18-8-6-16(7-9-18)10-11-19(12-21,13-24-15-22-14-23-24)17-4-2-1-3-5-17/h1-9,14-15H,10-11,13H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is identical to the substance Fenbuconazole 114369-43-6 4-(4-chlorophenyl)-2-phenyl-2-(1H-1,2,4-triazol-1-ylmethyl)butanenitrile Fenbuconazole C19H17ClN4 ClC1=CC=C(CCC(C#N)(CN3N=CN=C3)C2=CC=CC=C2)C=C1 InChI=1S/C19H17ClN4/c20-18-8-6-16(7-9-18)10-11-19(12-21,13-24-15-22-14-23-24)17-4-2-1-3-5-17/h1-9,14-15H,10-11,13H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is identical to the substance Fenbuconazole 114369-43-6 4-(4-chlorophenyl)-2-phenyl-2-(1H-1,2,4-triazol-1-ylmethyl)butanenitrile Fenbuconazole C19H17ClN4 ClC1=CC=C(CCC(C#N)(CN3N=CN=C3)C2=CC=CC=C2)C=C1 InChI=1S/C19H17ClN4/c20-18-8-6-16(7-9-18)10-11-19(12-21,13-24-15-22-14-23-24)17-4-2-1-3-5-17/h1-9,14-15H,10-11,13H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is identical to the substance Fenbuconazole 114369-43-6 4-(4-chlorophenyl)-2-phenyl-2-(1H-1,2,4-triazol-1-ylmethyl)butanenitrile Fenbuconazole C19H17ClN4 ClC1=CC=C(CCC(C#N)(CN3N=CN=C3)C2=CC=CC=C2)C=C1 InChI=1S/C19H17ClN4/c20-18-8-6-16(7-9-18)10-11-19(12-21,13-24-15-22-14-23-24)17-4-2-1-3-5-17/h1-9,14-15H,10-11,13H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is identical to the substance Fenbuconazole 114369-43-6 4-(4-chlorophenyl)-2-phenyl-2-(1H-1,2,4-triazol-1-ylmethyl)butanenitrile Fenbuconazole C19H17ClN4 ClC1=CC=C(CCC(C#N)(CN3N=CN=C3)C2=CC=CC=C2)C=C1 InChI=1S/C19H17ClN4/c20-18-8-6-16(7-9-18)10-11-19(12-21,13-24-15-22-14-23-24)17-4-2-1-3-5-17/h1-9,14-15H,10-11,13H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is identical to the substance Fenbuconazole 114369-43-6 4-(4-chlorophenyl)-2-phenyl-2-(1H-1,2,4-triazol-1-ylmethyl)butanenitrile Fenbuconazole C19H17ClN4 ClC1=CC=C(CCC(C#N)(CN3N=CN=C3)C2=CC=CC=C2)C=C1 InChI=1S/C19H17ClN4/c20-18-8-6-16(7-9-18)10-11-19(12-21,13-24-15-22-14-23-24)17-4-2-1-3-5-17/h1-9,14-15H,10-11,13H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is identical to the substance Fenbuconazole 114369-43-6 4-(4-chlorophenyl)-2-phenyl-2-(1H-1,2,4-triazol-1-ylmethyl)butanenitrile Fenbuconazole C19H17ClN4 ClC1=CC=C(CCC(C#N)(CN3N=CN=C3)C2=CC=CC=C2)C=C1 InChI=1S/C19H17ClN4/c20-18-8-6-16(7-9-18)10-11-19(12-21,13-24-15-22-14-23-24)17-4-2-1-3-5-17/h1-9,14-15H,10-11,13H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is identical to the substance Fenbuconazole 114369-43-6 4-(4-chlorophenyl)-2-phenyl-2-(1H-1,2,4-triazol-1-ylmethyl)butanenitrile Fenbuconazole C19H17ClN4 ClC1=CC=C(CCC(C#N)(CN3N=CN=C3)C2=CC=CC=C2)C=C1 InChI=1S/C19H17ClN4/c20-18-8-6-16(7-9-18)10-11-19(12-21,13-24-15-22-14-23-24)17-4-2-1-3-5-17/h1-9,14-15H,10-11,13H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is identical to the substance Fenbuconazole 114369-43-6 4-(4-chlorophenyl)-2-phenyl-2-(1H-1,2,4-triazol-1-ylmethyl)butanenitrile Fenbuconazole C19H17ClN4 ClC1=CC=C(CCC(C#N)(CN3N=CN=C3)C2=CC=CC=C2)C=C1 InChI=1S/C19H17ClN4/c20-18-8-6-16(7-9-18)10-11-19(12-21,13-24-15-22-14-23-24)17-4-2-1-3-5-17/h1-9,14-15H,10-11,13H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is identical to the substance Fenbuconazole 114369-43-6 4-(4-chlorophenyl)-2-phenyl-2-(1H-1,2,4-triazol-1-ylmethyl)butanenitrile Fenbuconazole C19H17ClN4 ClC1=CC=C(CCC(C#N)(CN3N=CN=C3)C2=CC=CC=C2)C=C1 InChI=1S/C19H17ClN4/c20-18-8-6-16(7-9-18)10-11-19(12-21,13-24-15-22-14-23-24)17-4-2-1-3-5-17/h1-9,14-15H,10-11,13H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is identical to the substance Fenbuconazole 114369-43-6 4-(4-chlorophenyl)-2-phenyl-2-(1H-1,2,4-triazol-1-ylmethyl)butanenitrile Fenbuconazole C19H17ClN4 ClC1=CC=C(CCC(C#N)(CN3N=CN=C3)C2=CC=CC=C2)C=C1 InChI=1S/C19H17ClN4/c20-18-8-6-16(7-9-18)10-11-19(12-21,13-24-15-22-14-23-24)17-4-2-1-3-5-17/h1-9,14-15H,10-11,13H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is identical to the substance Fenbuconazole 114369-43-6 4-(4-chlorophenyl)-2-phenyl-2-(1H-1,2,4-triazol-1-ylmethyl)butanenitrile Fenbuconazole C19H17ClN4 ClC1=CC=C(CCC(C#N)(CN3N=CN=C3)C2=CC=CC=C2)C=C1 InChI=1S/C19H17ClN4/c20-18-8-6-16(7-9-18)10-11-19(12-21,13-24-15-22-14-23-24)17-4-2-1-3-5-17/h1-9,14-15H,10-11,13H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is identical to the substance Fenbuconazole 114369-43-6 4-(4-chlorophenyl)-2-phenyl-2-(1H-1,2,4-triazol-1-ylmethyl)butanenitrile Fenbuconazole C19H17ClN4 ClC1=CC=C(CCC(C#N)(CN3N=CN=C3)C2=CC=CC=C2)C=C1 InChI=1S/C19H17ClN4/c20-18-8-6-16(7-9-18)10-11-19(12-21,13-24-15-22-14-23-24)17-4-2-1-3-5-17/h1-9,14-15H,10-11,13H2 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is identical to the substance Fenbuconazole 114369-43-6 4-(4-chlorophenyl)-2-phenyl-2-(1H-1,2,4-triazol-1-ylmethyl)butanenitrile Fenbuconazole C19H17ClN4 ClC1=CC=C(CCC(C#N)(CN3N=CN=C3)C2=CC=CC=C2)C=C1 InChI=1S/C19H17ClN4/c20-18-8-6-16(7-9-18)10-11-19(12-21,13-24-15-22-14-23-24)17-4-2-1-3-5-17/h1-9,14-15H,10-11,13H2 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is identical to the substance Fenbuconazole 114369-43-6 4-(4-chlorophenyl)-2-phenyl-2-(1H-1,2,4-triazol-1-ylmethyl)butanenitrile Fenbuconazole C19H17ClN4 ClC1=CC=C(CCC(C#N)(CN3N=CN=C3)C2=CC=CC=C2)C=C1 InChI=1S/C19H17ClN4/c20-18-8-6-16(7-9-18)10-11-19(12-21,13-24-15-22-14-23-24)17-4-2-1-3-5-17/h1-9,14-15H,10-11,13H2 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is identical to the substance Fenbuconazole 114369-43-6 4-(4-chlorophenyl)-2-phenyl-2-(1H-1,2,4-triazol-1-ylmethyl)butanenitrile Fenbuconazole C19H17ClN4 ClC1=CC=C(CCC(C#N)(CN3N=CN=C3)C2=CC=CC=C2)C=C1 InChI=1S/C19H17ClN4/c20-18-8-6-16(7-9-18)10-11-19(12-21,13-24-15-22-14-23-24)17-4-2-1-3-5-17/h1-9,14-15H,10-11,13H2 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is identical to the substance Fenbuconazole 114369-43-6 4-(4-chlorophenyl)-2-phenyl-2-(1H-1,2,4-triazol-1-ylmethyl)butanenitrile Fenbuconazole C19H17ClN4 ClC1=CC=C(CCC(C#N)(CN3N=CN=C3)C2=CC=CC=C2)C=C1 InChI=1S/C19H17ClN4/c20-18-8-6-16(7-9-18)10-11-19(12-21,13-24-15-22-14-23-24)17-4-2-1-3-5-17/h1-9,14-15H,10-11,13H2 organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is identical to the substance Fenbuconazole 114369-43-6 4-(4-chlorophenyl)-2-phenyl-2-(1H-1,2,4-triazol-1-ylmethyl)butanenitrile Fenbuconazole C19H17ClN4 ClC1=CC=C(CCC(C#N)(CN3N=CN=C3)C2=CC=CC=C2)C=C1 InChI=1S/C19H17ClN4/c20-18-8-6-16(7-9-18)10-11-19(12-21,13-24-15-22-14-23-24)17-4-2-1-3-5-17/h1-9,14-15H,10-11,13H2 organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Rat (as animal) Sprague-Dawley 10 Male/Female oral: gavage 48.0000000000 h yes not applicable Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) (k12)p3478 Not reported no data without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) W3110 Not reported no data without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) (k12)p3478 Not reported no data with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) W3110 Not reported no data with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Rat (as animal) hepatocytes Not reported yes without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair in vitro mammalian cell transformation assay in vitro No guideline available Not reported Not applicable Acceptable House mouse (as animal) fibroblast Not reported no data without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair in vitro mammalian cell transformation assay in vitro No guideline available Not reported Not applicable Acceptable House mouse (as animal) fibroblast Not reported no data with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair in vitro mammalian cell transformation assay in vitro No guideline available Not reported Not applicable Acceptable Hamster (as animal) kidney cells Not reported no data without Ambiguous RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair in vitro mammalian cell transformation assay in vitro No guideline available Not reported Not applicable Acceptable Hamster (as animal) kidney cells Not reported no data with Ambiguous RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable Hamster (as animal) Chinese 16 Male/Female oral: gavage 16.0000000000 h yes not applicable Negative no evidence RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable Hamster (as animal) Chinese 16 Male/Female oral: gavage 24.0000000000 h yes not applicable Negative no evidence RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable Hamster (as animal) Chinese 16 Male/Female oral: gavage 48.0000000000 h yes not applicable Negative no evidence RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) B6C3F1 5 Male intraperitoneal 48.0000000000 h no data not applicable Negative no evidence RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) B6C3F1 5 Male intraperitoneal 24.0000000000 h no data not applicable Negative no evidence RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) B6C3F1 5 Male intraperitoneal 72.0000000000 h no data not applicable Negative no evidence RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 24.0000000000 h no data not applicable Ambiguous no evidence RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 72.0000000000 h no data not applicable Ambiguous no evidence RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 48.0000000000 h no data not applicable Ambiguous no evidence RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance (3R,5S)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one (3R,5S)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one Not in list C19H16ClN3O2 O=C2O[C@@H](C[C@]2(Cn1ncnc1)c3ccccc3)c4ccc(Cl)cc4 InChI=1/C19H16ClN3O2/c20-16-8-6-14(7-9-16)17-10-19(18(24)25-17,11-23-13-21-12-22-23)15-4-2-1-3-5-15/h1-9,12-13,17H,10-11H2/t17-,19-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance (3R,5S)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one (3R,5S)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one Not in list C19H16ClN3O2 O=C2O[C@@H](C[C@]2(Cn1ncnc1)c3ccccc3)c4ccc(Cl)cc4 InChI=1/C19H16ClN3O2/c20-16-8-6-14(7-9-16)17-10-19(18(24)25-17,11-23-13-21-12-22-23)15-4-2-1-3-5-15/h1-9,12-13,17H,10-11H2/t17-,19-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance (3R,5S)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one (3R,5S)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one Not in list C19H16ClN3O2 O=C2O[C@@H](C[C@]2(Cn1ncnc1)c3ccccc3)c4ccc(Cl)cc4 InChI=1/C19H16ClN3O2/c20-16-8-6-14(7-9-16)17-10-19(18(24)25-17,11-23-13-21-12-22-23)15-4-2-1-3-5-15/h1-9,12-13,17H,10-11H2/t17-,19-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance (3R,5S)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one (3R,5S)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one Not in list C19H16ClN3O2 O=C2O[C@@H](C[C@]2(Cn1ncnc1)c3ccccc3)c4ccc(Cl)cc4 InChI=1/C19H16ClN3O2/c20-16-8-6-14(7-9-16)17-10-19(18(24)25-17,11-23-13-21-12-22-23)15-4-2-1-3-5-15/h1-9,12-13,17H,10-11H2/t17-,19-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance (3R,5S)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one (3R,5S)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one Not in list C19H16ClN3O2 O=C2O[C@@H](C[C@]2(Cn1ncnc1)c3ccccc3)c4ccc(Cl)cc4 InChI=1/C19H16ClN3O2/c20-16-8-6-14(7-9-16)17-10-19(18(24)25-17,11-23-13-21-12-22-23)15-4-2-1-3-5-15/h1-9,12-13,17H,10-11H2/t17-,19-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance (3R,5S)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one (3R,5S)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one Not in list C19H16ClN3O2 O=C2O[C@@H](C[C@]2(Cn1ncnc1)c3ccccc3)c4ccc(Cl)cc4 InChI=1/C19H16ClN3O2/c20-16-8-6-14(7-9-16)17-10-19(18(24)25-17,11-23-13-21-12-22-23)15-4-2-1-3-5-15/h1-9,12-13,17H,10-11H2/t17-,19-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance (3R,5S)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one (3R,5S)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one Not in list C19H16ClN3O2 O=C2O[C@@H](C[C@]2(Cn1ncnc1)c3ccccc3)c4ccc(Cl)cc4 InChI=1/C19H16ClN3O2/c20-16-8-6-14(7-9-16)17-10-19(18(24)25-17,11-23-13-21-12-22-23)15-4-2-1-3-5-15/h1-9,12-13,17H,10-11H2/t17-,19-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance (3R,5S)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one (3R,5S)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one Not in list C19H16ClN3O2 O=C2O[C@@H](C[C@]2(Cn1ncnc1)c3ccccc3)c4ccc(Cl)cc4 InChI=1/C19H16ClN3O2/c20-16-8-6-14(7-9-16)17-10-19(18(24)25-17,11-23-13-21-12-22-23)15-4-2-1-3-5-15/h1-9,12-13,17H,10-11H2/t17-,19-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance (3R,5S)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one (3R,5S)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one Not in list C19H16ClN3O2 O=C2O[C@@H](C[C@]2(Cn1ncnc1)c3ccccc3)c4ccc(Cl)cc4 InChI=1/C19H16ClN3O2/c20-16-8-6-14(7-9-16)17-10-19(18(24)25-17,11-23-13-21-12-22-23)15-4-2-1-3-5-15/h1-9,12-13,17H,10-11H2/t17-,19-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance (3R,5S)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one (3R,5S)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one Not in list C19H16ClN3O2 O=C2O[C@@H](C[C@]2(Cn1ncnc1)c3ccccc3)c4ccc(Cl)cc4 InChI=1/C19H16ClN3O2/c20-16-8-6-14(7-9-16)17-10-19(18(24)25-17,11-23-13-21-12-22-23)15-4-2-1-3-5-15/h1-9,12-13,17H,10-11H2/t17-,19-/m0/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance (3R,5R)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one (3R,5R)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one Not in list C19H16ClN3O2 O=C2O[C@H](C[C@]2(Cn1ncnc1)c3ccccc3)c4ccc(Cl)cc4 InChI=1/C19H16ClN3O2/c20-16-8-6-14(7-9-16)17-10-19(18(24)25-17,11-23-13-21-12-22-23)15-4-2-1-3-5-15/h1-9,12-13,17H,10-11H2/t17-,19+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance (3R,5R)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one (3R,5R)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one Not in list C19H16ClN3O2 O=C2O[C@H](C[C@]2(Cn1ncnc1)c3ccccc3)c4ccc(Cl)cc4 InChI=1/C19H16ClN3O2/c20-16-8-6-14(7-9-16)17-10-19(18(24)25-17,11-23-13-21-12-22-23)15-4-2-1-3-5-15/h1-9,12-13,17H,10-11H2/t17-,19+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance (3R,5R)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one (3R,5R)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one Not in list C19H16ClN3O2 O=C2O[C@H](C[C@]2(Cn1ncnc1)c3ccccc3)c4ccc(Cl)cc4 InChI=1/C19H16ClN3O2/c20-16-8-6-14(7-9-16)17-10-19(18(24)25-17,11-23-13-21-12-22-23)15-4-2-1-3-5-15/h1-9,12-13,17H,10-11H2/t17-,19+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance (3R,5R)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one (3R,5R)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one Not in list C19H16ClN3O2 O=C2O[C@H](C[C@]2(Cn1ncnc1)c3ccccc3)c4ccc(Cl)cc4 InChI=1/C19H16ClN3O2/c20-16-8-6-14(7-9-16)17-10-19(18(24)25-17,11-23-13-21-12-22-23)15-4-2-1-3-5-15/h1-9,12-13,17H,10-11H2/t17-,19+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance (3R,5R)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one (3R,5R)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one Not in list C19H16ClN3O2 O=C2O[C@H](C[C@]2(Cn1ncnc1)c3ccccc3)c4ccc(Cl)cc4 InChI=1/C19H16ClN3O2/c20-16-8-6-14(7-9-16)17-10-19(18(24)25-17,11-23-13-21-12-22-23)15-4-2-1-3-5-15/h1-9,12-13,17H,10-11H2/t17-,19+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance (3R,5R)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one (3R,5R)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one Not in list C19H16ClN3O2 O=C2O[C@H](C[C@]2(Cn1ncnc1)c3ccccc3)c4ccc(Cl)cc4 InChI=1/C19H16ClN3O2/c20-16-8-6-14(7-9-16)17-10-19(18(24)25-17,11-23-13-21-12-22-23)15-4-2-1-3-5-15/h1-9,12-13,17H,10-11H2/t17-,19+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance (3R,5R)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one (3R,5R)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one Not in list C19H16ClN3O2 O=C2O[C@H](C[C@]2(Cn1ncnc1)c3ccccc3)c4ccc(Cl)cc4 InChI=1/C19H16ClN3O2/c20-16-8-6-14(7-9-16)17-10-19(18(24)25-17,11-23-13-21-12-22-23)15-4-2-1-3-5-15/h1-9,12-13,17H,10-11H2/t17-,19+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance (3R,5R)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one (3R,5R)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one Not in list C19H16ClN3O2 O=C2O[C@H](C[C@]2(Cn1ncnc1)c3ccccc3)c4ccc(Cl)cc4 InChI=1/C19H16ClN3O2/c20-16-8-6-14(7-9-16)17-10-19(18(24)25-17,11-23-13-21-12-22-23)15-4-2-1-3-5-15/h1-9,12-13,17H,10-11H2/t17-,19+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance (3R,5R)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one (3R,5R)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one Not in list C19H16ClN3O2 O=C2O[C@H](C[C@]2(Cn1ncnc1)c3ccccc3)c4ccc(Cl)cc4 InChI=1/C19H16ClN3O2/c20-16-8-6-14(7-9-16)17-10-19(18(24)25-17,11-23-13-21-12-22-23)15-4-2-1-3-5-15/h1-9,12-13,17H,10-11H2/t17-,19+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Fenbuconazole 601-308-3 114369-43-6 single chemical entity Component is a metabolite of the substance (3R,5R)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one (3R,5R)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one Not in list C19H16ClN3O2 O=C2O[C@H](C[C@]2(Cn1ncnc1)c3ccccc3)c4ccc(Cl)cc4 InChI=1/C19H16ClN3O2/c20-16-8-6-14(7-9-16)17-10-19(18(24)25-17,11-23-13-21-12-22-23)15-4-2-1-3-5-15/h1-9,12-13,17H,10-11H2/t17-,19+/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: The United Kingdom Fenbuconazole 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole 13Apr2010 2010 doi:10.2903/j.efsa.2010.1558
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is identical to the substance Flupyrsulfuron-methyl-sodium 144740-54-5 sodium (4,6-dimethoxypyrimidin-2-yl)[({[3-(methoxycarbonyl)-6-(trifluoromethyl)pyridin-2-yl]sulfonyl}amino)carbonyl]azanide Not in list C15H13F3N5O7SNa COC1=CC(=NC(=N1)[N-]C(=O)NS(=O)(=O)C2=C(C=CC(=N2)C(F)(F)F)C(=O)OC)OC.[Na+] InChI=1S/C15H14F3N5O7S.Na/c1-28-9-6-10(29-2)21-13(20-9)22-14(25)23-31(26,27)11-7(12(24)30-3)4-5-8(19-11)15(16,17)18;/h4-6H,1-3H3,(H2,20,21,22,23,25);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle without Negative RMS: France Flupyrsulfuron-methyl (DPX-KE459) 1997 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is identical to the substance Flupyrsulfuron-methyl-sodium 144740-54-5 sodium (4,6-dimethoxypyrimidin-2-yl)[({[3-(methoxycarbonyl)-6-(trifluoromethyl)pyridin-2-yl]sulfonyl}amino)carbonyl]azanide Not in list C15H13F3N5O7SNa COC1=CC(=NC(=N1)[N-]C(=O)NS(=O)(=O)C2=C(C=CC(=N2)C(F)(F)F)C(=O)OC)OC.[Na+] InChI=1S/C15H14F3N5O7S.Na/c1-28-9-6-10(29-2)21-13(20-9)22-14(25)23-31(26,27)11-7(12(24)30-3)4-5-8(19-11)15(16,17)18;/h4-6H,1-3H3,(H2,20,21,22,23,25);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle without Negative RMS: France Flupyrsulfuron-methyl (DPX-KE459) 1997 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is identical to the substance Flupyrsulfuron-methyl-sodium 144740-54-5 sodium (4,6-dimethoxypyrimidin-2-yl)[({[3-(methoxycarbonyl)-6-(trifluoromethyl)pyridin-2-yl]sulfonyl}amino)carbonyl]azanide Not in list C15H13F3N5O7SNa COC1=CC(=NC(=N1)[N-]C(=O)NS(=O)(=O)C2=C(C=CC(=N2)C(F)(F)F)C(=O)OC)OC.[Na+] InChI=1S/C15H14F3N5O7S.Na/c1-28-9-6-10(29-2)21-13(20-9)22-14(25)23-31(26,27)11-7(12(24)30-3)4-5-8(19-11)15(16,17)18;/h4-6H,1-3H3,(H2,20,21,22,23,25);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Flupyrsulfuron-methyl (DPX-KE459) 1997 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is identical to the substance Flupyrsulfuron-methyl-sodium 144740-54-5 sodium (4,6-dimethoxypyrimidin-2-yl)[({[3-(methoxycarbonyl)-6-(trifluoromethyl)pyridin-2-yl]sulfonyl}amino)carbonyl]azanide Not in list C15H13F3N5O7SNa COC1=CC(=NC(=N1)[N-]C(=O)NS(=O)(=O)C2=C(C=CC(=N2)C(F)(F)F)C(=O)OC)OC.[Na+] InChI=1S/C15H14F3N5O7S.Na/c1-28-9-6-10(29-2)21-13(20-9)22-14(25)23-31(26,27)11-7(12(24)30-3)4-5-8(19-11)15(16,17)18;/h4-6H,1-3H3,(H2,20,21,22,23,25);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle with Negative RMS: France Flupyrsulfuron-methyl (DPX-KE459) 1997 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is identical to the substance Flupyrsulfuron-methyl-sodium 144740-54-5 sodium (4,6-dimethoxypyrimidin-2-yl)[({[3-(methoxycarbonyl)-6-(trifluoromethyl)pyridin-2-yl]sulfonyl}amino)carbonyl]azanide Not in list C15H13F3N5O7SNa COC1=CC(=NC(=N1)[N-]C(=O)NS(=O)(=O)C2=C(C=CC(=N2)C(F)(F)F)C(=O)OC)OC.[Na+] InChI=1S/C15H14F3N5O7S.Na/c1-28-9-6-10(29-2)21-13(20-9)22-14(25)23-31(26,27)11-7(12(24)30-3)4-5-8(19-11)15(16,17)18;/h4-6H,1-3H3,(H2,20,21,22,23,25);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Flupyrsulfuron-methyl (DPX-KE459) 1997 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is identical to the substance Flupyrsulfuron-methyl-sodium 144740-54-5 sodium (4,6-dimethoxypyrimidin-2-yl)[({[3-(methoxycarbonyl)-6-(trifluoromethyl)pyridin-2-yl]sulfonyl}amino)carbonyl]azanide Not in list C15H13F3N5O7SNa COC1=CC(=NC(=N1)[N-]C(=O)NS(=O)(=O)C2=C(C=CC(=N2)C(F)(F)F)C(=O)OC)OC.[Na+] InChI=1S/C15H14F3N5O7S.Na/c1-28-9-6-10(29-2)21-13(20-9)22-14(25)23-31(26,27)11-7(12(24)30-3)4-5-8(19-11)15(16,17)18;/h4-6H,1-3H3,(H2,20,21,22,23,25);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Flupyrsulfuron-methyl (DPX-KE459) 1997 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is identical to the substance Flupyrsulfuron-methyl-sodium 144740-54-5 sodium (4,6-dimethoxypyrimidin-2-yl)[({[3-(methoxycarbonyl)-6-(trifluoromethyl)pyridin-2-yl]sulfonyl}amino)carbonyl]azanide Not in list C15H13F3N5O7SNa COC1=CC(=NC(=N1)[N-]C(=O)NS(=O)(=O)C2=C(C=CC(=N2)C(F)(F)F)C(=O)OC)OC.[Na+] InChI=1S/C15H14F3N5O7S.Na/c1-28-9-6-10(29-2)21-13(20-9)22-14(25)23-31(26,27)11-7(12(24)30-3)4-5-8(19-11)15(16,17)18;/h4-6H,1-3H3,(H2,20,21,22,23,25);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Flupyrsulfuron-methyl (DPX-KE459) 1997 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is identical to the substance Flupyrsulfuron-methyl-sodium 144740-54-5 sodium (4,6-dimethoxypyrimidin-2-yl)[({[3-(methoxycarbonyl)-6-(trifluoromethyl)pyridin-2-yl]sulfonyl}amino)carbonyl]azanide Not in list C15H13F3N5O7SNa COC1=CC(=NC(=N1)[N-]C(=O)NS(=O)(=O)C2=C(C=CC(=N2)C(F)(F)F)C(=O)OC)OC.[Na+] InChI=1S/C15H14F3N5O7S.Na/c1-28-9-6-10(29-2)21-13(20-9)22-14(25)23-31(26,27)11-7(12(24)30-3)4-5-8(19-11)15(16,17)18;/h4-6H,1-3H3,(H2,20,21,22,23,25);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Flupyrsulfuron-methyl (DPX-KE459) 1997 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is identical to the substance Flupyrsulfuron-methyl-sodium 144740-54-5 sodium (4,6-dimethoxypyrimidin-2-yl)[({[3-(methoxycarbonyl)-6-(trifluoromethyl)pyridin-2-yl]sulfonyl}amino)carbonyl]azanide Not in list C15H13F3N5O7SNa COC1=CC(=NC(=N1)[N-]C(=O)NS(=O)(=O)C2=C(C=CC(=N2)C(F)(F)F)C(=O)OC)OC.[Na+] InChI=1S/C15H14F3N5O7S.Na/c1-28-9-6-10(29-2)21-13(20-9)22-14(25)23-31(26,27)11-7(12(24)30-3)4-5-8(19-11)15(16,17)18;/h4-6H,1-3H3,(H2,20,21,22,23,25);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle with Negative RMS: France Flupyrsulfuron-methyl (DPX-KE459) 1997 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is identical to the substance Flupyrsulfuron-methyl-sodium 144740-54-5 sodium (4,6-dimethoxypyrimidin-2-yl)[({[3-(methoxycarbonyl)-6-(trifluoromethyl)pyridin-2-yl]sulfonyl}amino)carbonyl]azanide Not in list C15H13F3N5O7SNa COC1=CC(=NC(=N1)[N-]C(=O)NS(=O)(=O)C2=C(C=CC(=N2)C(F)(F)F)C(=O)OC)OC.[Na+] InChI=1S/C15H14F3N5O7S.Na/c1-28-9-6-10(29-2)21-13(20-9)22-14(25)23-31(26,27)11-7(12(24)30-3)4-5-8(19-11)15(16,17)18;/h4-6H,1-3H3,(H2,20,21,22,23,25);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Flupyrsulfuron-methyl (DPX-KE459) 1997 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is identical to the substance Flupyrsulfuron-methyl-sodium 144740-54-5 sodium (4,6-dimethoxypyrimidin-2-yl)[({[3-(methoxycarbonyl)-6-(trifluoromethyl)pyridin-2-yl]sulfonyl}amino)carbonyl]azanide Not in list C15H13F3N5O7SNa COC1=CC(=NC(=N1)[N-]C(=O)NS(=O)(=O)C2=C(C=CC(=N2)C(F)(F)F)C(=O)OC)OC.[Na+] InChI=1S/C15H14F3N5O7S.Na/c1-28-9-6-10(29-2)21-13(20-9)22-14(25)23-31(26,27)11-7(12(24)30-3)4-5-8(19-11)15(16,17)18;/h4-6H,1-3H3,(H2,20,21,22,23,25);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes with Negative RMS: France Flupyrsulfuron-methyl (DPX-KE459) 1997 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is identical to the substance Flupyrsulfuron-methyl-sodium 144740-54-5 sodium (4,6-dimethoxypyrimidin-2-yl)[({[3-(methoxycarbonyl)-6-(trifluoromethyl)pyridin-2-yl]sulfonyl}amino)carbonyl]azanide Not in list C15H13F3N5O7SNa COC1=CC(=NC(=N1)[N-]C(=O)NS(=O)(=O)C2=C(C=CC(=N2)C(F)(F)F)C(=O)OC)OC.[Na+] InChI=1S/C15H14F3N5O7S.Na/c1-28-9-6-10(29-2)21-13(20-9)22-14(25)23-31(26,27)11-7(12(24)30-3)4-5-8(19-11)15(16,17)18;/h4-6H,1-3H3,(H2,20,21,22,23,25);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes without Negative RMS: France Flupyrsulfuron-methyl (DPX-KE459) 1997 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is identical to the substance Flupyrsulfuron-methyl-sodium 144740-54-5 sodium (4,6-dimethoxypyrimidin-2-yl)[({[3-(methoxycarbonyl)-6-(trifluoromethyl)pyridin-2-yl]sulfonyl}amino)carbonyl]azanide Not in list C15H13F3N5O7SNa COC1=CC(=NC(=N1)[N-]C(=O)NS(=O)(=O)C2=C(C=CC(=N2)C(F)(F)F)C(=O)OC)OC.[Na+] InChI=1S/C15H14F3N5O7S.Na/c1-28-9-6-10(29-2)21-13(20-9)22-14(25)23-31(26,27)11-7(12(24)30-3)4-5-8(19-11)15(16,17)18;/h4-6H,1-3H3,(H2,20,21,22,23,25);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported no data with Negative RMS: France Flupyrsulfuron-methyl (DPX-KE459) 1997 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is identical to the substance Flupyrsulfuron-methyl-sodium 144740-54-5 sodium (4,6-dimethoxypyrimidin-2-yl)[({[3-(methoxycarbonyl)-6-(trifluoromethyl)pyridin-2-yl]sulfonyl}amino)carbonyl]azanide Not in list C15H13F3N5O7SNa COC1=CC(=NC(=N1)[N-]C(=O)NS(=O)(=O)C2=C(C=CC(=N2)C(F)(F)F)C(=O)OC)OC.[Na+] InChI=1S/C15H14F3N5O7S.Na/c1-28-9-6-10(29-2)21-13(20-9)22-14(25)23-31(26,27)11-7(12(24)30-3)4-5-8(19-11)15(16,17)18;/h4-6H,1-3H3,(H2,20,21,22,23,25);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported no data without Negative RMS: France Flupyrsulfuron-methyl (DPX-KE459) 1997 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is identical to the substance Flupyrsulfuron-methyl-sodium 144740-54-5 sodium (4,6-dimethoxypyrimidin-2-yl)[({[3-(methoxycarbonyl)-6-(trifluoromethyl)pyridin-2-yl]sulfonyl}amino)carbonyl]azanide Not in list C15H13F3N5O7SNa COC1=CC(=NC(=N1)[N-]C(=O)NS(=O)(=O)C2=C(C=CC(=N2)C(F)(F)F)C(=O)OC)OC.[Na+] InChI=1S/C15H14F3N5O7S.Na/c1-28-9-6-10(29-2)21-13(20-9)22-14(25)23-31(26,27)11-7(12(24)30-3)4-5-8(19-11)15(16,17)18;/h4-6H,1-3H3,(H2,20,21,22,23,25);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: France Flupyrsulfuron-methyl (DPX-KE459) 1997 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is identical to the substance Flupyrsulfuron-methyl-sodium 144740-54-5 sodium (4,6-dimethoxypyrimidin-2-yl)[({[3-(methoxycarbonyl)-6-(trifluoromethyl)pyridin-2-yl]sulfonyl}amino)carbonyl]azanide Not in list C15H13F3N5O7SNa COC1=CC(=NC(=N1)[N-]C(=O)NS(=O)(=O)C2=C(C=CC(=N2)C(F)(F)F)C(=O)OC)OC.[Na+] InChI=1S/C15H14F3N5O7S.Na/c1-28-9-6-10(29-2)21-13(20-9)22-14(25)23-31(26,27)11-7(12(24)30-3)4-5-8(19-11)15(16,17)18;/h4-6H,1-3H3,(H2,20,21,22,23,25);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: France Flupyrsulfuron-methyl (DPX-KE459) 1997 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is identical to the substance Flupyrsulfuron-methyl-sodium 144740-54-5 sodium (4,6-dimethoxypyrimidin-2-yl)[({[3-(methoxycarbonyl)-6-(trifluoromethyl)pyridin-2-yl]sulfonyl}amino)carbonyl]azanide Not in list C15H13F3N5O7SNa COC1=CC(=NC(=N1)[N-]C(=O)NS(=O)(=O)C2=C(C=CC(=N2)C(F)(F)F)C(=O)OC)OC.[Na+] InChI=1S/C15H14F3N5O7S.Na/c1-28-9-6-10(29-2)21-13(20-9)22-14(25)23-31(26,27)11-7(12(24)30-3)4-5-8(19-11)15(16,17)18;/h4-6H,1-3H3,(H2,20,21,22,23,25);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 72.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: France Flupyrsulfuron-methyl (DPX-KE459) 1997 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is identical to the substance Flupyrsulfuron-methyl-sodium 144740-54-5 sodium (4,6-dimethoxypyrimidin-2-yl)[({[3-(methoxycarbonyl)-6-(trifluoromethyl)pyridin-2-yl]sulfonyl}amino)carbonyl]azanide Not in list C15H13F3N5O7SNa COC1=CC(=NC(=N1)[N-]C(=O)NS(=O)(=O)C2=C(C=CC(=N2)C(F)(F)F)C(=O)OC)OC.[Na+] InChI=1S/C15H14F3N5O7S.Na/c1-28-9-6-10(29-2)21-13(20-9)22-14(25)23-31(26,27)11-7(12(24)30-3)4-5-8(19-11)15(16,17)18;/h4-6H,1-3H3,(H2,20,21,22,23,25);/q;+1/p-1 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: France Flupyrsulfuron-methyl (DPX-KE459) 1997 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is a metabolite of the substance 1-(4,6-dimethoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione 1-(4,6-dimethoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione Not in list C14H10F3N5O4 FC(F)(F)c1ccc2c(n1)N(C(=O)NC2=O)c3nc(OC)cc(OC)n3 InChI=1/C14H10F3N5O4/c1-25-8-5-9(26-2)20-12(19-8)22-10-6(11(23)21-13(22)24)3-4-7(18-10)14(15,16)17/h3-5H,1-2H3,(H,21,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Denmark Flupyrsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is a metabolite of the substance 1-(4,6-dimethoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione 1-(4,6-dimethoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione Not in list C14H10F3N5O4 FC(F)(F)c1ccc2c(n1)N(C(=O)NC2=O)c3nc(OC)cc(OC)n3 InChI=1/C14H10F3N5O4/c1-25-8-5-9(26-2)20-12(19-8)22-10-6(11(23)21-13(22)24)3-4-7(18-10)14(15,16)17/h3-5H,1-2H3,(H,21,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Denmark Flupyrsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is a metabolite of the substance 1-(4,6-dimethoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione 1-(4,6-dimethoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione Not in list C14H10F3N5O4 FC(F)(F)c1ccc2c(n1)N(C(=O)NC2=O)c3nc(OC)cc(OC)n3 InChI=1/C14H10F3N5O4/c1-25-8-5-9(26-2)20-12(19-8)22-10-6(11(23)21-13(22)24)3-4-7(18-10)14(15,16)17/h3-5H,1-2H3,(H,21,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Denmark Flupyrsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is a metabolite of the substance 1-(4,6-dimethoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione 1-(4,6-dimethoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione Not in list C14H10F3N5O4 FC(F)(F)c1ccc2c(n1)N(C(=O)NC2=O)c3nc(OC)cc(OC)n3 InChI=1/C14H10F3N5O4/c1-25-8-5-9(26-2)20-12(19-8)22-10-6(11(23)21-13(22)24)3-4-7(18-10)14(15,16)17/h3-5H,1-2H3,(H,21,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Denmark Flupyrsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is a metabolite of the substance 1-(4,6-dimethoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione 1-(4,6-dimethoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione Not in list C14H10F3N5O4 FC(F)(F)c1ccc2c(n1)N(C(=O)NC2=O)c3nc(OC)cc(OC)n3 InChI=1/C14H10F3N5O4/c1-25-8-5-9(26-2)20-12(19-8)22-10-6(11(23)21-13(22)24)3-4-7(18-10)14(15,16)17/h3-5H,1-2H3,(H,21,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Denmark Flupyrsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is a metabolite of the substance 1-(4,6-dimethoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione 1-(4,6-dimethoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione Not in list C14H10F3N5O4 FC(F)(F)c1ccc2c(n1)N(C(=O)NC2=O)c3nc(OC)cc(OC)n3 InChI=1/C14H10F3N5O4/c1-25-8-5-9(26-2)20-12(19-8)22-10-6(11(23)21-13(22)24)3-4-7(18-10)14(15,16)17/h3-5H,1-2H3,(H,21,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Denmark Flupyrsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is a metabolite of the substance 1-(4,6-dimethoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione 1-(4,6-dimethoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione Not in list C14H10F3N5O4 FC(F)(F)c1ccc2c(n1)N(C(=O)NC2=O)c3nc(OC)cc(OC)n3 InChI=1/C14H10F3N5O4/c1-25-8-5-9(26-2)20-12(19-8)22-10-6(11(23)21-13(22)24)3-4-7(18-10)14(15,16)17/h3-5H,1-2H3,(H,21,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Denmark Flupyrsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is a metabolite of the substance 1-(4,6-dimethoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione 1-(4,6-dimethoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione Not in list C14H10F3N5O4 FC(F)(F)c1ccc2c(n1)N(C(=O)NC2=O)c3nc(OC)cc(OC)n3 InChI=1/C14H10F3N5O4/c1-25-8-5-9(26-2)20-12(19-8)22-10-6(11(23)21-13(22)24)3-4-7(18-10)14(15,16)17/h3-5H,1-2H3,(H,21,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Denmark Flupyrsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is a metabolite of the substance 1-(4,6-dimethoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione 1-(4,6-dimethoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione Not in list C14H10F3N5O4 FC(F)(F)c1ccc2c(n1)N(C(=O)NC2=O)c3nc(OC)cc(OC)n3 InChI=1/C14H10F3N5O4/c1-25-8-5-9(26-2)20-12(19-8)22-10-6(11(23)21-13(22)24)3-4-7(18-10)14(15,16)17/h3-5H,1-2H3,(H,21,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Denmark Flupyrsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is a metabolite of the substance 1-(4,6-dimethoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione 1-(4,6-dimethoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione Not in list C14H10F3N5O4 FC(F)(F)c1ccc2c(n1)N(C(=O)NC2=O)c3nc(OC)cc(OC)n3 InChI=1/C14H10F3N5O4/c1-25-8-5-9(26-2)20-12(19-8)22-10-6(11(23)21-13(22)24)3-4-7(18-10)14(15,16)17/h3-5H,1-2H3,(H,21,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Denmark Flupyrsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is a metabolite of the substance 1-(4,6-dimethoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione 1-(4,6-dimethoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione Not in list C14H10F3N5O4 FC(F)(F)c1ccc2c(n1)N(C(=O)NC2=O)c3nc(OC)cc(OC)n3 InChI=1/C14H10F3N5O4/c1-25-8-5-9(26-2)20-12(19-8)22-10-6(11(23)21-13(22)24)3-4-7(18-10)14(15,16)17/h3-5H,1-2H3,(H,21,23,24) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: France - CoRMS: Denmark Flupyrsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is a metabolite of the substance 1-(4,6-dimethoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione 1-(4,6-dimethoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione Not in list C14H10F3N5O4 FC(F)(F)c1ccc2c(n1)N(C(=O)NC2=O)c3nc(OC)cc(OC)n3 InChI=1/C14H10F3N5O4/c1-25-8-5-9(26-2)20-12(19-8)22-10-6(11(23)21-13(22)24)3-4-7(18-10)14(15,16)17/h3-5H,1-2H3,(H,21,23,24) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: France - CoRMS: Denmark Flupyrsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is a metabolite of the substance 1-(4,6-dimethoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione 1-(4,6-dimethoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione Not in list C14H10F3N5O4 FC(F)(F)c1ccc2c(n1)N(C(=O)NC2=O)c3nc(OC)cc(OC)n3 InChI=1/C14H10F3N5O4/c1-25-8-5-9(26-2)20-12(19-8)22-10-6(11(23)21-13(22)24)3-4-7(18-10)14(15,16)17/h3-5H,1-2H3,(H,21,23,24) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Denmark Flupyrsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is a metabolite of the substance 1-(4,6-dimethoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione 1-(4,6-dimethoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione Not in list C14H10F3N5O4 FC(F)(F)c1ccc2c(n1)N(C(=O)NC2=O)c3nc(OC)cc(OC)n3 InChI=1/C14H10F3N5O4/c1-25-8-5-9(26-2)20-12(19-8)22-10-6(11(23)21-13(22)24)3-4-7(18-10)14(15,16)17/h3-5H,1-2H3,(H,21,23,24) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Denmark Flupyrsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is a metabolite of the substance 1-(4-hydroxy-6-methoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione 1-(4-hydroxy-6-methoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione Not in list C13H8F3N5O4 FC(F)(F)c1ccc2c(n1)N(C(=O)NC2=O)c3nc(O)cc(OC)n3 InChI=1/C13H8F3N5O4/c1-25-8-4-7(22)18-11(19-8)21-9-5(10(23)20-12(21)24)2-3-6(17-9)13(14,15)16/h2-4H,1H3,(H,18,19,22)(H,20,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Denmark Flupyrsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is a metabolite of the substance 1-(4-hydroxy-6-methoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione 1-(4-hydroxy-6-methoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione Not in list C13H8F3N5O4 FC(F)(F)c1ccc2c(n1)N(C(=O)NC2=O)c3nc(O)cc(OC)n3 InChI=1/C13H8F3N5O4/c1-25-8-4-7(22)18-11(19-8)21-9-5(10(23)20-12(21)24)2-3-6(17-9)13(14,15)16/h2-4H,1H3,(H,18,19,22)(H,20,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Denmark Flupyrsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is a metabolite of the substance 1-(4-hydroxy-6-methoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione 1-(4-hydroxy-6-methoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione Not in list C13H8F3N5O4 FC(F)(F)c1ccc2c(n1)N(C(=O)NC2=O)c3nc(O)cc(OC)n3 InChI=1/C13H8F3N5O4/c1-25-8-4-7(22)18-11(19-8)21-9-5(10(23)20-12(21)24)2-3-6(17-9)13(14,15)16/h2-4H,1H3,(H,18,19,22)(H,20,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Denmark Flupyrsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is a metabolite of the substance 1-(4-hydroxy-6-methoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione 1-(4-hydroxy-6-methoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione Not in list C13H8F3N5O4 FC(F)(F)c1ccc2c(n1)N(C(=O)NC2=O)c3nc(O)cc(OC)n3 InChI=1/C13H8F3N5O4/c1-25-8-4-7(22)18-11(19-8)21-9-5(10(23)20-12(21)24)2-3-6(17-9)13(14,15)16/h2-4H,1H3,(H,18,19,22)(H,20,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Denmark Flupyrsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is a metabolite of the substance 1-(4-hydroxy-6-methoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione 1-(4-hydroxy-6-methoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione Not in list C13H8F3N5O4 FC(F)(F)c1ccc2c(n1)N(C(=O)NC2=O)c3nc(O)cc(OC)n3 InChI=1/C13H8F3N5O4/c1-25-8-4-7(22)18-11(19-8)21-9-5(10(23)20-12(21)24)2-3-6(17-9)13(14,15)16/h2-4H,1H3,(H,18,19,22)(H,20,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Denmark Flupyrsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is a metabolite of the substance 1-(4-hydroxy-6-methoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione 1-(4-hydroxy-6-methoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione Not in list C13H8F3N5O4 FC(F)(F)c1ccc2c(n1)N(C(=O)NC2=O)c3nc(O)cc(OC)n3 InChI=1/C13H8F3N5O4/c1-25-8-4-7(22)18-11(19-8)21-9-5(10(23)20-12(21)24)2-3-6(17-9)13(14,15)16/h2-4H,1H3,(H,18,19,22)(H,20,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Denmark Flupyrsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is a metabolite of the substance 1-(4-hydroxy-6-methoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione 1-(4-hydroxy-6-methoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione Not in list C13H8F3N5O4 FC(F)(F)c1ccc2c(n1)N(C(=O)NC2=O)c3nc(O)cc(OC)n3 InChI=1/C13H8F3N5O4/c1-25-8-4-7(22)18-11(19-8)21-9-5(10(23)20-12(21)24)2-3-6(17-9)13(14,15)16/h2-4H,1H3,(H,18,19,22)(H,20,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Denmark Flupyrsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is a metabolite of the substance 1-(4-hydroxy-6-methoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione 1-(4-hydroxy-6-methoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione Not in list C13H8F3N5O4 FC(F)(F)c1ccc2c(n1)N(C(=O)NC2=O)c3nc(O)cc(OC)n3 InChI=1/C13H8F3N5O4/c1-25-8-4-7(22)18-11(19-8)21-9-5(10(23)20-12(21)24)2-3-6(17-9)13(14,15)16/h2-4H,1H3,(H,18,19,22)(H,20,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Denmark Flupyrsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is a metabolite of the substance 1-(4-hydroxy-6-methoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione 1-(4-hydroxy-6-methoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione Not in list C13H8F3N5O4 FC(F)(F)c1ccc2c(n1)N(C(=O)NC2=O)c3nc(O)cc(OC)n3 InChI=1/C13H8F3N5O4/c1-25-8-4-7(22)18-11(19-8)21-9-5(10(23)20-12(21)24)2-3-6(17-9)13(14,15)16/h2-4H,1H3,(H,18,19,22)(H,20,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Denmark Flupyrsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is a metabolite of the substance 1-(4-hydroxy-6-methoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione 1-(4-hydroxy-6-methoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione Not in list C13H8F3N5O4 FC(F)(F)c1ccc2c(n1)N(C(=O)NC2=O)c3nc(O)cc(OC)n3 InChI=1/C13H8F3N5O4/c1-25-8-4-7(22)18-11(19-8)21-9-5(10(23)20-12(21)24)2-3-6(17-9)13(14,15)16/h2-4H,1H3,(H,18,19,22)(H,20,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Denmark Flupyrsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is a metabolite of the substance 1-(4-hydroxy-6-methoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione 1-(4-hydroxy-6-methoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione Not in list C13H8F3N5O4 FC(F)(F)c1ccc2c(n1)N(C(=O)NC2=O)c3nc(O)cc(OC)n3 InChI=1/C13H8F3N5O4/c1-25-8-4-7(22)18-11(19-8)21-9-5(10(23)20-12(21)24)2-3-6(17-9)13(14,15)16/h2-4H,1H3,(H,18,19,22)(H,20,23,24) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: France - CoRMS: Denmark Flupyrsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is a metabolite of the substance 1-(4-hydroxy-6-methoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione 1-(4-hydroxy-6-methoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione Not in list C13H8F3N5O4 FC(F)(F)c1ccc2c(n1)N(C(=O)NC2=O)c3nc(O)cc(OC)n3 InChI=1/C13H8F3N5O4/c1-25-8-4-7(22)18-11(19-8)21-9-5(10(23)20-12(21)24)2-3-6(17-9)13(14,15)16/h2-4H,1H3,(H,18,19,22)(H,20,23,24) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: France - CoRMS: Denmark Flupyrsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is a metabolite of the substance 1-(4-hydroxy-6-methoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione 1-(4-hydroxy-6-methoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione Not in list C13H8F3N5O4 FC(F)(F)c1ccc2c(n1)N(C(=O)NC2=O)c3nc(O)cc(OC)n3 InChI=1/C13H8F3N5O4/c1-25-8-4-7(22)18-11(19-8)21-9-5(10(23)20-12(21)24)2-3-6(17-9)13(14,15)16/h2-4H,1H3,(H,18,19,22)(H,20,23,24) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes without Negative RMS: France - CoRMS: Denmark Flupyrsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is a metabolite of the substance 1-(4-hydroxy-6-methoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione 1-(4-hydroxy-6-methoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione Not in list C13H8F3N5O4 FC(F)(F)c1ccc2c(n1)N(C(=O)NC2=O)c3nc(O)cc(OC)n3 InChI=1/C13H8F3N5O4/c1-25-8-4-7(22)18-11(19-8)21-9-5(10(23)20-12(21)24)2-3-6(17-9)13(14,15)16/h2-4H,1H3,(H,18,19,22)(H,20,23,24) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes with Negative RMS: France - CoRMS: Denmark Flupyrsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is a metabolite of the substance 2-sulfamoyl-6-(trifluoromethyl)nicotinic acid 2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylic acid Not in list C7H5F3N2O4S FC(F)(F)c1ccc(C(O)=O)c(n1)S(N)(=O)=O InChI=1/C7H5F3N2O4S/c8-7(9,10)4-2-1-3(6(13)14)5(12-4)17(11,15)16/h1-2H,(H,13,14)(H2,11,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Denmark Flupyrsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is a metabolite of the substance 2-sulfamoyl-6-(trifluoromethyl)nicotinic acid 2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylic acid Not in list C7H5F3N2O4S FC(F)(F)c1ccc(C(O)=O)c(n1)S(N)(=O)=O InChI=1/C7H5F3N2O4S/c8-7(9,10)4-2-1-3(6(13)14)5(12-4)17(11,15)16/h1-2H,(H,13,14)(H2,11,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Denmark Flupyrsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is a metabolite of the substance 2-sulfamoyl-6-(trifluoromethyl)nicotinic acid 2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylic acid Not in list C7H5F3N2O4S FC(F)(F)c1ccc(C(O)=O)c(n1)S(N)(=O)=O InChI=1/C7H5F3N2O4S/c8-7(9,10)4-2-1-3(6(13)14)5(12-4)17(11,15)16/h1-2H,(H,13,14)(H2,11,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Denmark Flupyrsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is a metabolite of the substance 2-sulfamoyl-6-(trifluoromethyl)nicotinic acid 2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylic acid Not in list C7H5F3N2O4S FC(F)(F)c1ccc(C(O)=O)c(n1)S(N)(=O)=O InChI=1/C7H5F3N2O4S/c8-7(9,10)4-2-1-3(6(13)14)5(12-4)17(11,15)16/h1-2H,(H,13,14)(H2,11,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Denmark Flupyrsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is a metabolite of the substance 2-sulfamoyl-6-(trifluoromethyl)nicotinic acid 2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylic acid Not in list C7H5F3N2O4S FC(F)(F)c1ccc(C(O)=O)c(n1)S(N)(=O)=O InChI=1/C7H5F3N2O4S/c8-7(9,10)4-2-1-3(6(13)14)5(12-4)17(11,15)16/h1-2H,(H,13,14)(H2,11,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Denmark Flupyrsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is a metabolite of the substance 2-sulfamoyl-6-(trifluoromethyl)nicotinic acid 2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylic acid Not in list C7H5F3N2O4S FC(F)(F)c1ccc(C(O)=O)c(n1)S(N)(=O)=O InChI=1/C7H5F3N2O4S/c8-7(9,10)4-2-1-3(6(13)14)5(12-4)17(11,15)16/h1-2H,(H,13,14)(H2,11,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Denmark Flupyrsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is a metabolite of the substance 2-sulfamoyl-6-(trifluoromethyl)nicotinic acid 2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylic acid Not in list C7H5F3N2O4S FC(F)(F)c1ccc(C(O)=O)c(n1)S(N)(=O)=O InChI=1/C7H5F3N2O4S/c8-7(9,10)4-2-1-3(6(13)14)5(12-4)17(11,15)16/h1-2H,(H,13,14)(H2,11,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Denmark Flupyrsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is a metabolite of the substance 2-sulfamoyl-6-(trifluoromethyl)nicotinic acid 2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylic acid Not in list C7H5F3N2O4S FC(F)(F)c1ccc(C(O)=O)c(n1)S(N)(=O)=O InChI=1/C7H5F3N2O4S/c8-7(9,10)4-2-1-3(6(13)14)5(12-4)17(11,15)16/h1-2H,(H,13,14)(H2,11,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Denmark Flupyrsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is a metabolite of the substance 2-sulfamoyl-6-(trifluoromethyl)nicotinic acid 2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylic acid Not in list C7H5F3N2O4S FC(F)(F)c1ccc(C(O)=O)c(n1)S(N)(=O)=O InChI=1/C7H5F3N2O4S/c8-7(9,10)4-2-1-3(6(13)14)5(12-4)17(11,15)16/h1-2H,(H,13,14)(H2,11,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Denmark Flupyrsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is a metabolite of the substance 2-sulfamoyl-6-(trifluoromethyl)nicotinic acid 2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylic acid Not in list C7H5F3N2O4S FC(F)(F)c1ccc(C(O)=O)c(n1)S(N)(=O)=O InChI=1/C7H5F3N2O4S/c8-7(9,10)4-2-1-3(6(13)14)5(12-4)17(11,15)16/h1-2H,(H,13,14)(H2,11,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Denmark Flupyrsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is a metabolite of the substance 2-sulfamoyl-6-(trifluoromethyl)nicotinic acid 2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylic acid Not in list C7H5F3N2O4S FC(F)(F)c1ccc(C(O)=O)c(n1)S(N)(=O)=O InChI=1/C7H5F3N2O4S/c8-7(9,10)4-2-1-3(6(13)14)5(12-4)17(11,15)16/h1-2H,(H,13,14)(H2,11,15,16) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Denmark Flupyrsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is a metabolite of the substance 2-sulfamoyl-6-(trifluoromethyl)nicotinic acid 2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylic acid Not in list C7H5F3N2O4S FC(F)(F)c1ccc(C(O)=O)c(n1)S(N)(=O)=O InChI=1/C7H5F3N2O4S/c8-7(9,10)4-2-1-3(6(13)14)5(12-4)17(11,15)16/h1-2H,(H,13,14)(H2,11,15,16) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Denmark Flupyrsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is a metabolite of the substance 2-sulfamoyl-6-(trifluoromethyl)nicotinic acid 2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylic acid Not in list C7H5F3N2O4S FC(F)(F)c1ccc(C(O)=O)c(n1)S(N)(=O)=O InChI=1/C7H5F3N2O4S/c8-7(9,10)4-2-1-3(6(13)14)5(12-4)17(11,15)16/h1-2H,(H,13,14)(H2,11,15,16) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes with Negative RMS: France - CoRMS: Denmark Flupyrsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is a metabolite of the substance 2-sulfamoyl-6-(trifluoromethyl)nicotinic acid 2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylic acid Not in list C7H5F3N2O4S FC(F)(F)c1ccc(C(O)=O)c(n1)S(N)(=O)=O InChI=1/C7H5F3N2O4S/c8-7(9,10)4-2-1-3(6(13)14)5(12-4)17(11,15)16/h1-2H,(H,13,14)(H2,11,15,16) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes without Negative RMS: France - CoRMS: Denmark Flupyrsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is a metabolite of the substance methyl 2-sulfamoyl-6-(trifluoromethyl)nicotinate methyl 2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylate Not in list C8H7F3N2O4S FC(F)(F)c1ccc(C(=O)OC)c(n1)S(N)(=O)=O InChI=1/C8H7F3N2O4S/c1-17-7(14)4-2-3-5(8(9,10)11)13-6(4)18(12,15)16/h2-3H,1H3,(H2,12,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Denmark Flupyrsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is a metabolite of the substance methyl 2-sulfamoyl-6-(trifluoromethyl)nicotinate methyl 2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylate Not in list C8H7F3N2O4S FC(F)(F)c1ccc(C(=O)OC)c(n1)S(N)(=O)=O InChI=1/C8H7F3N2O4S/c1-17-7(14)4-2-3-5(8(9,10)11)13-6(4)18(12,15)16/h2-3H,1H3,(H2,12,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Denmark Flupyrsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is a metabolite of the substance methyl 2-sulfamoyl-6-(trifluoromethyl)nicotinate methyl 2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylate Not in list C8H7F3N2O4S FC(F)(F)c1ccc(C(=O)OC)c(n1)S(N)(=O)=O InChI=1/C8H7F3N2O4S/c1-17-7(14)4-2-3-5(8(9,10)11)13-6(4)18(12,15)16/h2-3H,1H3,(H2,12,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Denmark Flupyrsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is a metabolite of the substance methyl 2-sulfamoyl-6-(trifluoromethyl)nicotinate methyl 2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylate Not in list C8H7F3N2O4S FC(F)(F)c1ccc(C(=O)OC)c(n1)S(N)(=O)=O InChI=1/C8H7F3N2O4S/c1-17-7(14)4-2-3-5(8(9,10)11)13-6(4)18(12,15)16/h2-3H,1H3,(H2,12,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Denmark Flupyrsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is a metabolite of the substance methyl 2-sulfamoyl-6-(trifluoromethyl)nicotinate methyl 2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylate Not in list C8H7F3N2O4S FC(F)(F)c1ccc(C(=O)OC)c(n1)S(N)(=O)=O InChI=1/C8H7F3N2O4S/c1-17-7(14)4-2-3-5(8(9,10)11)13-6(4)18(12,15)16/h2-3H,1H3,(H2,12,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Denmark Flupyrsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is a metabolite of the substance methyl 2-sulfamoyl-6-(trifluoromethyl)nicotinate methyl 2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylate Not in list C8H7F3N2O4S FC(F)(F)c1ccc(C(=O)OC)c(n1)S(N)(=O)=O InChI=1/C8H7F3N2O4S/c1-17-7(14)4-2-3-5(8(9,10)11)13-6(4)18(12,15)16/h2-3H,1H3,(H2,12,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Denmark Flupyrsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is a metabolite of the substance methyl 2-sulfamoyl-6-(trifluoromethyl)nicotinate methyl 2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylate Not in list C8H7F3N2O4S FC(F)(F)c1ccc(C(=O)OC)c(n1)S(N)(=O)=O InChI=1/C8H7F3N2O4S/c1-17-7(14)4-2-3-5(8(9,10)11)13-6(4)18(12,15)16/h2-3H,1H3,(H2,12,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Denmark Flupyrsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is a metabolite of the substance methyl 2-sulfamoyl-6-(trifluoromethyl)nicotinate methyl 2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylate Not in list C8H7F3N2O4S FC(F)(F)c1ccc(C(=O)OC)c(n1)S(N)(=O)=O InChI=1/C8H7F3N2O4S/c1-17-7(14)4-2-3-5(8(9,10)11)13-6(4)18(12,15)16/h2-3H,1H3,(H2,12,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Denmark Flupyrsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is a metabolite of the substance methyl 2-sulfamoyl-6-(trifluoromethyl)nicotinate methyl 2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylate Not in list C8H7F3N2O4S FC(F)(F)c1ccc(C(=O)OC)c(n1)S(N)(=O)=O InChI=1/C8H7F3N2O4S/c1-17-7(14)4-2-3-5(8(9,10)11)13-6(4)18(12,15)16/h2-3H,1H3,(H2,12,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Denmark Flupyrsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is a metabolite of the substance methyl 2-sulfamoyl-6-(trifluoromethyl)nicotinate methyl 2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylate Not in list C8H7F3N2O4S FC(F)(F)c1ccc(C(=O)OC)c(n1)S(N)(=O)=O InChI=1/C8H7F3N2O4S/c1-17-7(14)4-2-3-5(8(9,10)11)13-6(4)18(12,15)16/h2-3H,1H3,(H2,12,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Denmark Flupyrsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is a metabolite of the substance methyl 2-sulfamoyl-6-(trifluoromethyl)nicotinate methyl 2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylate Not in list C8H7F3N2O4S FC(F)(F)c1ccc(C(=O)OC)c(n1)S(N)(=O)=O InChI=1/C8H7F3N2O4S/c1-17-7(14)4-2-3-5(8(9,10)11)13-6(4)18(12,15)16/h2-3H,1H3,(H2,12,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Denmark Flupyrsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is a metabolite of the substance methyl 2-sulfamoyl-6-(trifluoromethyl)nicotinate methyl 2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylate Not in list C8H7F3N2O4S FC(F)(F)c1ccc(C(=O)OC)c(n1)S(N)(=O)=O InChI=1/C8H7F3N2O4S/c1-17-7(14)4-2-3-5(8(9,10)11)13-6(4)18(12,15)16/h2-3H,1H3,(H2,12,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Denmark Flupyrsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is a metabolite of the substance methyl 2-sulfamoyl-6-(trifluoromethyl)nicotinate methyl 2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylate Not in list C8H7F3N2O4S FC(F)(F)c1ccc(C(=O)OC)c(n1)S(N)(=O)=O InChI=1/C8H7F3N2O4S/c1-17-7(14)4-2-3-5(8(9,10)11)13-6(4)18(12,15)16/h2-3H,1H3,(H2,12,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Denmark Flupyrsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is a metabolite of the substance methyl 2-sulfamoyl-6-(trifluoromethyl)nicotinate methyl 2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylate Not in list C8H7F3N2O4S FC(F)(F)c1ccc(C(=O)OC)c(n1)S(N)(=O)=O InChI=1/C8H7F3N2O4S/c1-17-7(14)4-2-3-5(8(9,10)11)13-6(4)18(12,15)16/h2-3H,1H3,(H2,12,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Denmark Flupyrsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is a metabolite of the substance methyl 2-sulfamoyl-6-(trifluoromethyl)nicotinate methyl 2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylate Not in list C8H7F3N2O4S FC(F)(F)c1ccc(C(=O)OC)c(n1)S(N)(=O)=O InChI=1/C8H7F3N2O4S/c1-17-7(14)4-2-3-5(8(9,10)11)13-6(4)18(12,15)16/h2-3H,1H3,(H2,12,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Denmark Flupyrsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is a metabolite of the substance methyl 2-sulfamoyl-6-(trifluoromethyl)nicotinate methyl 2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylate Not in list C8H7F3N2O4S FC(F)(F)c1ccc(C(=O)OC)c(n1)S(N)(=O)=O InChI=1/C8H7F3N2O4S/c1-17-7(14)4-2-3-5(8(9,10)11)13-6(4)18(12,15)16/h2-3H,1H3,(H2,12,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Denmark Flupyrsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is a metabolite of the substance methyl 2-sulfamoyl-6-(trifluoromethyl)nicotinate methyl 2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylate Not in list C8H7F3N2O4S FC(F)(F)c1ccc(C(=O)OC)c(n1)S(N)(=O)=O InChI=1/C8H7F3N2O4S/c1-17-7(14)4-2-3-5(8(9,10)11)13-6(4)18(12,15)16/h2-3H,1H3,(H2,12,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France - CoRMS: Denmark Flupyrsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is a metabolite of the substance methyl 2-sulfamoyl-6-(trifluoromethyl)nicotinate methyl 2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylate Not in list C8H7F3N2O4S FC(F)(F)c1ccc(C(=O)OC)c(n1)S(N)(=O)=O InChI=1/C8H7F3N2O4S/c1-17-7(14)4-2-3-5(8(9,10)11)13-6(4)18(12,15)16/h2-3H,1H3,(H2,12,15,16) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: France - CoRMS: Denmark Flupyrsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is a metabolite of the substance methyl 2-sulfamoyl-6-(trifluoromethyl)nicotinate methyl 2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylate Not in list C8H7F3N2O4S FC(F)(F)c1ccc(C(=O)OC)c(n1)S(N)(=O)=O InChI=1/C8H7F3N2O4S/c1-17-7(14)4-2-3-5(8(9,10)11)13-6(4)18(12,15)16/h2-3H,1H3,(H2,12,15,16) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes without Positive RMS: France - CoRMS: Denmark Flupyrsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is a metabolite of the substance methyl 2-sulfamoyl-6-(trifluoromethyl)nicotinate methyl 2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylate Not in list C8H7F3N2O4S FC(F)(F)c1ccc(C(=O)OC)c(n1)S(N)(=O)=O InChI=1/C8H7F3N2O4S/c1-17-7(14)4-2-3-5(8(9,10)11)13-6(4)18(12,15)16/h2-3H,1H3,(H2,12,15,16) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes with Positive RMS: France - CoRMS: Denmark Flupyrsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is a metabolite of the substance methyl 2-sulfamoyl-6-(trifluoromethyl)nicotinate methyl 2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylate Not in list C8H7F3N2O4S FC(F)(F)c1ccc(C(=O)OC)c(n1)S(N)(=O)=O InChI=1/C8H7F3N2O4S/c1-17-7(14)4-2-3-5(8(9,10)11)13-6(4)18(12,15)16/h2-3H,1H3,(H2,12,15,16) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Not reported 10 Male/Female oral: unspecified 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: France - CoRMS: Denmark Flupyrsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Flupyrsulfuron-methyl-sodium 144740-54-5 single chemical entity Component is a metabolite of the substance methyl 2-sulfamoyl-6-(trifluoromethyl)nicotinate methyl 2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylate Not in list C8H7F3N2O4S FC(F)(F)c1ccc(C(=O)OC)c(n1)S(N)(=O)=O InChI=1/C8H7F3N2O4S/c1-17-7(14)4-2-3-5(8(9,10)11)13-6(4)18(12,15)16/h2-3H,1H3,(H2,12,15,16) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Not reported 10 Male/Female oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: France - CoRMS: Denmark Flupyrsulfuron-methyl 2014 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium) 06Nov2014 2014 doi:10.2903/j.efsa.2014.3881
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is part of a group but not included in the group assessment Thiophanate-methyl 245-740-7 23564-05-8 methyl N-[[2-(methoxycarbonylcarbamothioylamino)phenyl]carbamothioyl]carbamate Thiophanate-methyl C12H14N4O4S2 COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC InChI=1S/C12H14N4O4S2/c1-19-11(17)15-9(21)13-7-5-3-4-6-8(7)14-10(22)16-12(18)20-2/h3-6H,1-2H3,(H2,13,15,17,21)(H2,14,16,18,22) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian cell micronucleus test in vitro According to OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Germany Carbendazim, Benomyl, Thiophanate-methyl (Addendum) 2002 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is part of a group but not included in the group assessment Thiophanate-methyl 245-740-7 23564-05-8 methyl N-[[2-(methoxycarbonylcarbamothioylamino)phenyl]carbamothioyl]carbamate Thiophanate-methyl C12H14N4O4S2 COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC InChI=1S/C12H14N4O4S2/c1-19-11(17)15-9(21)13-7-5-3-4-6-8(7)14-10(22)16-12(18)20-2/h3-6H,1-2H3,(H2,13,15,17,21)(H2,14,16,18,22) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian cell micronucleus test in vitro According to OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Positive RMS: Germany Carbendazim, Benomyl, Thiophanate-methyl (Addendum) 2002 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Carbendazim 234-232-0 10605-21-7 single chemical entity Component is part of a group but not included in the group assessment Thiophanate-methyl 245-740-7 23564-05-8 methyl N-[[2-(methoxycarbonylcarbamothioylamino)phenyl]carbamothioyl]carbamate Thiophanate-methyl C12H14N4O4S2 COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC InChI=1S/C12H14N4O4S2/c1-19-11(17)15-9(21)13-7-5-3-4-6-8(7)14-10(22)16-12(18)20-2/h3-6H,1-2H3,(H2,13,15,17,21)(H2,14,16,18,22) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration other in vitro No guideline available Not reported Not applicable Acceptable Human (as organism) lymphocytes Not reported no data not applicable Positive RMS: Germany Carbendazim, Benomyl, Thiophanate-methyl (Addendum) 2002 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim 12May2010 2010 doi:10.2903/j.efsa.2010.1598
+Tebufenozide 112410-23-8 single chemical entity Component is identical to the substance Tebufenozide 112410-23-8 N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide Tebufenozide C22H28N2O2 O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1 InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is identical to the substance Tebufenozide 112410-23-8 N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide Tebufenozide C22H28N2O2 O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1 InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is identical to the substance Tebufenozide 112410-23-8 N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide Tebufenozide C22H28N2O2 O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1 InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is identical to the substance Tebufenozide 112410-23-8 N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide Tebufenozide C22H28N2O2 O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1 InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is identical to the substance Tebufenozide 112410-23-8 N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide Tebufenozide C22H28N2O2 O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1 InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is identical to the substance Tebufenozide 112410-23-8 N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide Tebufenozide C22H28N2O2 O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1 InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is identical to the substance Tebufenozide 112410-23-8 N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide Tebufenozide C22H28N2O2 O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1 InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is identical to the substance Tebufenozide 112410-23-8 N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide Tebufenozide C22H28N2O2 O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1 InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is identical to the substance Tebufenozide 112410-23-8 N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide Tebufenozide C22H28N2O2 O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1 InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is identical to the substance Tebufenozide 112410-23-8 N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide Tebufenozide C22H28N2O2 O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1 InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is identical to the substance Tebufenozide 112410-23-8 N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide Tebufenozide C22H28N2O2 O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1 InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is identical to the substance Tebufenozide 112410-23-8 N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide Tebufenozide C22H28N2O2 O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1 InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is identical to the substance Tebufenozide 112410-23-8 N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide Tebufenozide C22H28N2O2 O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1 InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is identical to the substance Tebufenozide 112410-23-8 N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide Tebufenozide C22H28N2O2 O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1 InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is identical to the substance Tebufenozide 112410-23-8 N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide Tebufenozide C22H28N2O2 O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1 InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is identical to the substance Tebufenozide 112410-23-8 N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide Tebufenozide C22H28N2O2 O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1 InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is identical to the substance Tebufenozide 112410-23-8 N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide Tebufenozide C22H28N2O2 O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1 InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is identical to the substance Tebufenozide 112410-23-8 N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide Tebufenozide C22H28N2O2 O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1 InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is identical to the substance Tebufenozide 112410-23-8 N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide Tebufenozide C22H28N2O2 O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1 InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is identical to the substance Tebufenozide 112410-23-8 N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide Tebufenozide C22H28N2O2 O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1 InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is identical to the substance Tebufenozide 112410-23-8 N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide Tebufenozide C22H28N2O2 O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1 InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25) organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is identical to the substance Tebufenozide 112410-23-8 N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide Tebufenozide C22H28N2O2 O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1 InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25) organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Rat (as animal) Sprague-Dawley 10 Male/Female oral: gavage 48.0000000000 h yes not applicable Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is identical to the substance Tebufenozide 112410-23-8 N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide Tebufenozide C22H28N2O2 O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1 InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25) organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Rat (as animal) Sprague-Dawley 10 Male/Female oral: gavage 24.0000000000 h yes not applicable Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is identical to the substance Tebufenozide 112410-23-8 N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide Tebufenozide C22H28N2O2 O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1 InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25) organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Rat (as animal) Sprague-Dawley 10 Male/Female oral: gavage 6.0000000000 h yes not applicable Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide Not in list C22H26N2O3 Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C InChI=1/C22H26N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13H,1-6H3,(H,23,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide Not in list C22H26N2O3 Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C InChI=1/C22H26N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13H,1-6H3,(H,23,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide Not in list C22H26N2O3 Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C InChI=1/C22H26N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13H,1-6H3,(H,23,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide Not in list C22H26N2O3 Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C InChI=1/C22H26N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13H,1-6H3,(H,23,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide Not in list C22H26N2O3 Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C InChI=1/C22H26N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13H,1-6H3,(H,23,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide Not in list C22H26N2O3 Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C InChI=1/C22H26N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13H,1-6H3,(H,23,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide Not in list C22H26N2O3 Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C InChI=1/C22H26N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13H,1-6H3,(H,23,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide Not in list C22H26N2O3 Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C InChI=1/C22H26N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13H,1-6H3,(H,23,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide Not in list C22H26N2O3 Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C InChI=1/C22H26N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13H,1-6H3,(H,23,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide Not in list C22H26N2O3 Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C InChI=1/C22H26N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13H,1-6H3,(H,23,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance 4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)benzoic acid 4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)benzoic acid Not in list C21H24N2O4 Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(O)=O)C(C)(C)C InChI=1/C21H24N2O4/c1-13-10-14(2)12-17(11-13)19(25)23(21(3,4)5)22-18(24)15-6-8-16(9-7-15)20(26)27/h6-12H,1-5H3,(H,22,24)(H,26,27) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent no treatment with Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance 4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)benzoic acid 4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)benzoic acid Not in list C21H24N2O4 Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(O)=O)C(C)(C)C InChI=1/C21H24N2O4/c1-13-10-14(2)12-17(11-13)19(25)23(21(3,4)5)22-18(24)15-6-8-16(9-7-15)20(26)27/h6-12H,1-5H3,(H,22,24)(H,26,27) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent no treatment with Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance 4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)benzoic acid 4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)benzoic acid Not in list C21H24N2O4 Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(O)=O)C(C)(C)C InChI=1/C21H24N2O4/c1-13-10-14(2)12-17(11-13)19(25)23(21(3,4)5)22-18(24)15-6-8-16(9-7-15)20(26)27/h6-12H,1-5H3,(H,22,24)(H,26,27) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent no treatment without Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance 4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)benzoic acid 4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)benzoic acid Not in list C21H24N2O4 Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(O)=O)C(C)(C)C InChI=1/C21H24N2O4/c1-13-10-14(2)12-17(11-13)19(25)23(21(3,4)5)22-18(24)15-6-8-16(9-7-15)20(26)27/h6-12H,1-5H3,(H,22,24)(H,26,27) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent no treatment without Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance 4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)benzoic acid 4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)benzoic acid Not in list C21H24N2O4 Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(O)=O)C(C)(C)C InChI=1/C21H24N2O4/c1-13-10-14(2)12-17(11-13)19(25)23(21(3,4)5)22-18(24)15-6-8-16(9-7-15)20(26)27/h6-12H,1-5H3,(H,22,24)(H,26,27) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent no treatment with Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance 4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)benzoic acid 4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)benzoic acid Not in list C21H24N2O4 Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(O)=O)C(C)(C)C InChI=1/C21H24N2O4/c1-13-10-14(2)12-17(11-13)19(25)23(21(3,4)5)22-18(24)15-6-8-16(9-7-15)20(26)27/h6-12H,1-5H3,(H,22,24)(H,26,27) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent no treatment without Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance 4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)benzoic acid 4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)benzoic acid Not in list C21H24N2O4 Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(O)=O)C(C)(C)C InChI=1/C21H24N2O4/c1-13-10-14(2)12-17(11-13)19(25)23(21(3,4)5)22-18(24)15-6-8-16(9-7-15)20(26)27/h6-12H,1-5H3,(H,22,24)(H,26,27) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent no treatment with Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance 4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)benzoic acid 4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)benzoic acid Not in list C21H24N2O4 Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(O)=O)C(C)(C)C InChI=1/C21H24N2O4/c1-13-10-14(2)12-17(11-13)19(25)23(21(3,4)5)22-18(24)15-6-8-16(9-7-15)20(26)27/h6-12H,1-5H3,(H,22,24)(H,26,27) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent no treatment without Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance 4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)benzoic acid 4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)benzoic acid Not in list C21H24N2O4 Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(O)=O)C(C)(C)C InChI=1/C21H24N2O4/c1-13-10-14(2)12-17(11-13)19(25)23(21(3,4)5)22-18(24)15-6-8-16(9-7-15)20(26)27/h6-12H,1-5H3,(H,22,24)(H,26,27) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent no treatment with Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance 4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)benzoic acid 4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)benzoic acid Not in list C21H24N2O4 Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(O)=O)C(C)(C)C InChI=1/C21H24N2O4/c1-13-10-14(2)12-17(11-13)19(25)23(21(3,4)5)22-18(24)15-6-8-16(9-7-15)20(26)27/h6-12H,1-5H3,(H,22,24)(H,26,27) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent no treatment without Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide Not in list C22H28N2O3 Cc1cc(cc(CO)c1)C(=O)N(NC(=O)c2ccc(CC)cc2)C(C)(C)C InChI=1/C22H28N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-13,25H,6,14H2,1-5H3,(H,23,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide Not in list C22H28N2O3 Cc1cc(cc(CO)c1)C(=O)N(NC(=O)c2ccc(CC)cc2)C(C)(C)C InChI=1/C22H28N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-13,25H,6,14H2,1-5H3,(H,23,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide Not in list C22H28N2O3 Cc1cc(cc(CO)c1)C(=O)N(NC(=O)c2ccc(CC)cc2)C(C)(C)C InChI=1/C22H28N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-13,25H,6,14H2,1-5H3,(H,23,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide Not in list C22H28N2O3 Cc1cc(cc(CO)c1)C(=O)N(NC(=O)c2ccc(CC)cc2)C(C)(C)C InChI=1/C22H28N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-13,25H,6,14H2,1-5H3,(H,23,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide Not in list C22H28N2O3 Cc1cc(cc(CO)c1)C(=O)N(NC(=O)c2ccc(CC)cc2)C(C)(C)C InChI=1/C22H28N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-13,25H,6,14H2,1-5H3,(H,23,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide Not in list C22H28N2O3 Cc1cc(cc(CO)c1)C(=O)N(NC(=O)c2ccc(CC)cc2)C(C)(C)C InChI=1/C22H28N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-13,25H,6,14H2,1-5H3,(H,23,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide Not in list C22H28N2O3 Cc1cc(cc(CO)c1)C(=O)N(NC(=O)c2ccc(CC)cc2)C(C)(C)C InChI=1/C22H28N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-13,25H,6,14H2,1-5H3,(H,23,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide Not in list C22H28N2O3 Cc1cc(cc(CO)c1)C(=O)N(NC(=O)c2ccc(CC)cc2)C(C)(C)C InChI=1/C22H28N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-13,25H,6,14H2,1-5H3,(H,23,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide Not in list C22H28N2O3 Cc1cc(cc(CO)c1)C(=O)N(NC(=O)c2ccc(CC)cc2)C(C)(C)C InChI=1/C22H28N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-13,25H,6,14H2,1-5H3,(H,23,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide Not in list C22H28N2O3 Cc1cc(cc(CO)c1)C(=O)N(NC(=O)c2ccc(CC)cc2)C(C)(C)C InChI=1/C22H28N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-13,25H,6,14H2,1-5H3,(H,23,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3-(hydroxymethyl)-5-methylbenzohydrazide conjugates Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3-(hydroxymethyl)-5-methylbenzohydrazide conjugates Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle without Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3-(hydroxymethyl)-5-methylbenzohydrazide conjugates Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle with Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3-(hydroxymethyl)-5-methylbenzohydrazide conjugates Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3-(hydroxymethyl)-5-methylbenzohydrazide conjugates Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3-(hydroxymethyl)-5-methylbenzohydrazide conjugates Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3-(hydroxymethyl)-5-methylbenzohydrazide conjugates Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3-(hydroxymethyl)-5-methylbenzohydrazide conjugates Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3-(hydroxymethyl)-5-methylbenzohydrazide conjugates Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3-(hydroxymethyl)-5-methylbenzohydrazide conjugates Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance 5-({2-[(4-acetylphenyl)carbonyl]-1-tert-butylhydrazinyl}carbonyl)benzene-1,3-dicarboxylic acid 5-({2-[(4-acetylphenyl)carbonyl]-1-tert-butylhydrazinyl}carbonyl)benzene-1,3-dicarboxylic acid Not in list C22H22N2O7 O=C(O)c1cc(cc(c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C)C(O)=O InChI=1/C22H22N2O7/c1-12(25)13-5-7-14(8-6-13)18(26)23-24(22(2,3)4)19(27)15-9-16(20(28)29)11-17(10-15)21(30)31/h5-11H,1-4H3,(H,23,26)(H,28,29)(H,30,31) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle with Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance 5-({2-[(4-acetylphenyl)carbonyl]-1-tert-butylhydrazinyl}carbonyl)benzene-1,3-dicarboxylic acid 5-({2-[(4-acetylphenyl)carbonyl]-1-tert-butylhydrazinyl}carbonyl)benzene-1,3-dicarboxylic acid Not in list C22H22N2O7 O=C(O)c1cc(cc(c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C)C(O)=O InChI=1/C22H22N2O7/c1-12(25)13-5-7-14(8-6-13)18(26)23-24(22(2,3)4)19(27)15-9-16(20(28)29)11-17(10-15)21(30)31/h5-11H,1-4H3,(H,23,26)(H,28,29)(H,30,31) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance 5-({2-[(4-acetylphenyl)carbonyl]-1-tert-butylhydrazinyl}carbonyl)benzene-1,3-dicarboxylic acid 5-({2-[(4-acetylphenyl)carbonyl]-1-tert-butylhydrazinyl}carbonyl)benzene-1,3-dicarboxylic acid Not in list C22H22N2O7 O=C(O)c1cc(cc(c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C)C(O)=O InChI=1/C22H22N2O7/c1-12(25)13-5-7-14(8-6-13)18(26)23-24(22(2,3)4)19(27)15-9-16(20(28)29)11-17(10-15)21(30)31/h5-11H,1-4H3,(H,23,26)(H,28,29)(H,30,31) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance 5-({2-[(4-acetylphenyl)carbonyl]-1-tert-butylhydrazinyl}carbonyl)benzene-1,3-dicarboxylic acid 5-({2-[(4-acetylphenyl)carbonyl]-1-tert-butylhydrazinyl}carbonyl)benzene-1,3-dicarboxylic acid Not in list C22H22N2O7 O=C(O)c1cc(cc(c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C)C(O)=O InChI=1/C22H22N2O7/c1-12(25)13-5-7-14(8-6-13)18(26)23-24(22(2,3)4)19(27)15-9-16(20(28)29)11-17(10-15)21(30)31/h5-11H,1-4H3,(H,23,26)(H,28,29)(H,30,31) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle without Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance 5-({2-[(4-acetylphenyl)carbonyl]-1-tert-butylhydrazinyl}carbonyl)benzene-1,3-dicarboxylic acid 5-({2-[(4-acetylphenyl)carbonyl]-1-tert-butylhydrazinyl}carbonyl)benzene-1,3-dicarboxylic acid Not in list C22H22N2O7 O=C(O)c1cc(cc(c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C)C(O)=O InChI=1/C22H22N2O7/c1-12(25)13-5-7-14(8-6-13)18(26)23-24(22(2,3)4)19(27)15-9-16(20(28)29)11-17(10-15)21(30)31/h5-11H,1-4H3,(H,23,26)(H,28,29)(H,30,31) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance 5-({2-[(4-acetylphenyl)carbonyl]-1-tert-butylhydrazinyl}carbonyl)benzene-1,3-dicarboxylic acid 5-({2-[(4-acetylphenyl)carbonyl]-1-tert-butylhydrazinyl}carbonyl)benzene-1,3-dicarboxylic acid Not in list C22H22N2O7 O=C(O)c1cc(cc(c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C)C(O)=O InChI=1/C22H22N2O7/c1-12(25)13-5-7-14(8-6-13)18(26)23-24(22(2,3)4)19(27)15-9-16(20(28)29)11-17(10-15)21(30)31/h5-11H,1-4H3,(H,23,26)(H,28,29)(H,30,31) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance 5-({2-[(4-acetylphenyl)carbonyl]-1-tert-butylhydrazinyl}carbonyl)benzene-1,3-dicarboxylic acid 5-({2-[(4-acetylphenyl)carbonyl]-1-tert-butylhydrazinyl}carbonyl)benzene-1,3-dicarboxylic acid Not in list C22H22N2O7 O=C(O)c1cc(cc(c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C)C(O)=O InChI=1/C22H22N2O7/c1-12(25)13-5-7-14(8-6-13)18(26)23-24(22(2,3)4)19(27)15-9-16(20(28)29)11-17(10-15)21(30)31/h5-11H,1-4H3,(H,23,26)(H,28,29)(H,30,31) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance 5-({2-[(4-acetylphenyl)carbonyl]-1-tert-butylhydrazinyl}carbonyl)benzene-1,3-dicarboxylic acid 5-({2-[(4-acetylphenyl)carbonyl]-1-tert-butylhydrazinyl}carbonyl)benzene-1,3-dicarboxylic acid Not in list C22H22N2O7 O=C(O)c1cc(cc(c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C)C(O)=O InChI=1/C22H22N2O7/c1-12(25)13-5-7-14(8-6-13)18(26)23-24(22(2,3)4)19(27)15-9-16(20(28)29)11-17(10-15)21(30)31/h5-11H,1-4H3,(H,23,26)(H,28,29)(H,30,31) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance 5-({2-[(4-acetylphenyl)carbonyl]-1-tert-butylhydrazinyl}carbonyl)benzene-1,3-dicarboxylic acid 5-({2-[(4-acetylphenyl)carbonyl]-1-tert-butylhydrazinyl}carbonyl)benzene-1,3-dicarboxylic acid Not in list C22H22N2O7 O=C(O)c1cc(cc(c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C)C(O)=O InChI=1/C22H22N2O7/c1-12(25)13-5-7-14(8-6-13)18(26)23-24(22(2,3)4)19(27)15-9-16(20(28)29)11-17(10-15)21(30)31/h5-11H,1-4H3,(H,23,26)(H,28,29)(H,30,31) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance 5-({2-[(4-acetylphenyl)carbonyl]-1-tert-butylhydrazinyl}carbonyl)benzene-1,3-dicarboxylic acid 5-({2-[(4-acetylphenyl)carbonyl]-1-tert-butylhydrazinyl}carbonyl)benzene-1,3-dicarboxylic acid Not in list C22H22N2O7 O=C(O)c1cc(cc(c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C)C(O)=O InChI=1/C22H22N2O7/c1-12(25)13-5-7-14(8-6-13)18(26)23-24(22(2,3)4)19(27)15-9-16(20(28)29)11-17(10-15)21(30)31/h5-11H,1-4H3,(H,23,26)(H,28,29)(H,30,31) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance [4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)phenyl]acetic acid [4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)phenyl]acetic acid Not in list C22H26N2O4 O=C(O)Cc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C InChI=1/C22H26N2O4/c1-14-10-15(2)12-18(11-14)21(28)24(22(3,4)5)23-20(27)17-8-6-16(7-9-17)13-19(25)26/h6-12H,13H2,1-5H3,(H,23,27)(H,25,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance [4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)phenyl]acetic acid [4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)phenyl]acetic acid Not in list C22H26N2O4 O=C(O)Cc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C InChI=1/C22H26N2O4/c1-14-10-15(2)12-18(11-14)21(28)24(22(3,4)5)23-20(27)17-8-6-16(7-9-17)13-19(25)26/h6-12H,13H2,1-5H3,(H,23,27)(H,25,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance [4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)phenyl]acetic acid [4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)phenyl]acetic acid Not in list C22H26N2O4 O=C(O)Cc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C InChI=1/C22H26N2O4/c1-14-10-15(2)12-18(11-14)21(28)24(22(3,4)5)23-20(27)17-8-6-16(7-9-17)13-19(25)26/h6-12H,13H2,1-5H3,(H,23,27)(H,25,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance [4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)phenyl]acetic acid [4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)phenyl]acetic acid Not in list C22H26N2O4 O=C(O)Cc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C InChI=1/C22H26N2O4/c1-14-10-15(2)12-18(11-14)21(28)24(22(3,4)5)23-20(27)17-8-6-16(7-9-17)13-19(25)26/h6-12H,13H2,1-5H3,(H,23,27)(H,25,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance [4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)phenyl]acetic acid [4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)phenyl]acetic acid Not in list C22H26N2O4 O=C(O)Cc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C InChI=1/C22H26N2O4/c1-14-10-15(2)12-18(11-14)21(28)24(22(3,4)5)23-20(27)17-8-6-16(7-9-17)13-19(25)26/h6-12H,13H2,1-5H3,(H,23,27)(H,25,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance [4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)phenyl]acetic acid [4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)phenyl]acetic acid Not in list C22H26N2O4 O=C(O)Cc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C InChI=1/C22H26N2O4/c1-14-10-15(2)12-18(11-14)21(28)24(22(3,4)5)23-20(27)17-8-6-16(7-9-17)13-19(25)26/h6-12H,13H2,1-5H3,(H,23,27)(H,25,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance [4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)phenyl]acetic acid [4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)phenyl]acetic acid Not in list C22H26N2O4 O=C(O)Cc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C InChI=1/C22H26N2O4/c1-14-10-15(2)12-18(11-14)21(28)24(22(3,4)5)23-20(27)17-8-6-16(7-9-17)13-19(25)26/h6-12H,13H2,1-5H3,(H,23,27)(H,25,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance [4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)phenyl]acetic acid [4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)phenyl]acetic acid Not in list C22H26N2O4 O=C(O)Cc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C InChI=1/C22H26N2O4/c1-14-10-15(2)12-18(11-14)21(28)24(22(3,4)5)23-20(27)17-8-6-16(7-9-17)13-19(25)26/h6-12H,13H2,1-5H3,(H,23,27)(H,25,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide Not in list C22H28N2O3 OC(C)c1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C InChI=1/C22H28N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13,16,25H,1-6H3,(H,23,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide Not in list C22H28N2O3 OC(C)c1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C InChI=1/C22H28N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13,16,25H,1-6H3,(H,23,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide Not in list C22H28N2O3 OC(C)c1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C InChI=1/C22H28N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13,16,25H,1-6H3,(H,23,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide Not in list C22H28N2O3 OC(C)c1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C InChI=1/C22H28N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13,16,25H,1-6H3,(H,23,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide Not in list C22H28N2O3 OC(C)c1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C InChI=1/C22H28N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13,16,25H,1-6H3,(H,23,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide Not in list C22H28N2O3 OC(C)c1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C InChI=1/C22H28N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13,16,25H,1-6H3,(H,23,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide Not in list C22H28N2O3 OC(C)c1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C InChI=1/C22H28N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13,16,25H,1-6H3,(H,23,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide Not in list C22H28N2O3 OC(C)c1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C InChI=1/C22H28N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13,16,25H,1-6H3,(H,23,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide Not in list C22H28N2O3 OC(C)c1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C InChI=1/C22H28N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13,16,25H,1-6H3,(H,23,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide Not in list C22H28N2O3 OC(C)c1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C InChI=1/C22H28N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13,16,25H,1-6H3,(H,23,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide Not in list C22H26N2O3 CCc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C=O)c2)C(C)(C)C InChI=1/C22H26N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-14H,6H2,1-5H3,(H,23,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide Not in list C22H26N2O3 CCc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C=O)c2)C(C)(C)C InChI=1/C22H26N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-14H,6H2,1-5H3,(H,23,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide Not in list C22H26N2O3 CCc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C=O)c2)C(C)(C)C InChI=1/C22H26N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-14H,6H2,1-5H3,(H,23,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide Not in list C22H26N2O3 CCc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C=O)c2)C(C)(C)C InChI=1/C22H26N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-14H,6H2,1-5H3,(H,23,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide Not in list C22H26N2O3 CCc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C=O)c2)C(C)(C)C InChI=1/C22H26N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-14H,6H2,1-5H3,(H,23,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide Not in list C22H26N2O3 CCc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C=O)c2)C(C)(C)C InChI=1/C22H26N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-14H,6H2,1-5H3,(H,23,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide Not in list C22H26N2O3 CCc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C=O)c2)C(C)(C)C InChI=1/C22H26N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-14H,6H2,1-5H3,(H,23,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide Not in list C22H26N2O3 CCc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C=O)c2)C(C)(C)C InChI=1/C22H26N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-14H,6H2,1-5H3,(H,23,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide Not in list C22H26N2O3 CCc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C=O)c2)C(C)(C)C InChI=1/C22H26N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-14H,6H2,1-5H3,(H,23,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tebufenozide 112410-23-8 single chemical entity Component is a metabolite of the substance N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide Not in list C22H26N2O3 CCc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C=O)c2)C(C)(C)C InChI=1/C22H26N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-14H,6H2,1-5H3,(H,23,26) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany Tebufenozide 2005 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide 14Dec2010 2010 doi:10.2903/j.efsa.2010.1871
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany Tefluthrin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany Tefluthrin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany Tefluthrin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Germany Tefluthrin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Germany Tefluthrin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany Tefluthrin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany Tefluthrin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany Tefluthrin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany Tefluthrin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany Tefluthrin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle with Negative RMS: Germany Tefluthrin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle without Negative RMS: Germany Tefluthrin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Germany Tefluthrin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Germany Tefluthrin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported no data without Negative RMS: Germany Tefluthrin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported no data with Negative RMS: Germany Tefluthrin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported no data without Negative RMS: Germany Tefluthrin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Not reported Male/Female oral: gavage 48.0000000000 h yes not applicable Negative RMS: Germany Tefluthrin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Not reported Male/Female oral: gavage 24.0000000000 h yes not applicable Negative RMS: Germany Tefluthrin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Not reported Male/Female oral: gavage 12.0000000000 h yes not applicable Negative RMS: Germany Tefluthrin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) C57BL Male/Female intraperitoneal 72.0000000000 h yes not applicable Negative no evidence RMS: Germany Tefluthrin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) C57BL Male/Female intraperitoneal 48.0000000000 h yes not applicable Negative no evidence RMS: Germany Tefluthrin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) C57BL Male/Female intraperitoneal 24.0000000000 h yes not applicable Ambiguous no evidence RMS: Germany Tefluthrin 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Germany Tefluthrin (Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Germany Tefluthrin (Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Germany Tefluthrin (Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Germany Tefluthrin (Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: Germany Tefluthrin (Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Germany Tefluthrin (Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Germany Tefluthrin (Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: Germany Tefluthrin (Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: Germany Tefluthrin (Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Germany Tefluthrin (Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: Germany Tefluthrin (Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Germany Tefluthrin (Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: Germany Tefluthrin (Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: Germany Tefluthrin (Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: Germany Tefluthrin (Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: Germany Tefluthrin (Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Germany Tefluthrin (Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Germany Tefluthrin (Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Germany Tefluthrin (Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Germany Tefluthrin (Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Germany Tefluthrin (Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Germany Tefluthrin (Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Germany Tefluthrin (Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Germany Tefluthrin (Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes without Negative RMS: Germany Tefluthrin (Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes with Negative RMS: Germany Tefluthrin (Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 Not reported yes without Negative RMS: Germany Tefluthrin (Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 Not reported yes with Negative RMS: Germany Tefluthrin (Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Germany Tefluthrin (Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Germany Tefluthrin (Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Germany Tefluthrin (Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Germany Tefluthrin (Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Germany Tefluthrin (Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Germany Tefluthrin (Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Germany Tefluthrin (Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Germany Tefluthrin (Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes without Negative RMS: Germany Tefluthrin (Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes with Negative RMS: Germany Tefluthrin (Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Germany Tefluthrin (Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Germany Tefluthrin (Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Germany Tefluthrin (Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Germany Tefluthrin (Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Germany Tefluthrin (Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Germany Tefluthrin (Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Germany Tefluthrin (Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Germany Tefluthrin (Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes without Negative RMS: Germany Tefluthrin (Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Tefluthrin 79538-32-2 single chemical entity Component is identical to the substance Tefluthrin 79538-32-2 2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate Tefluthrin C17H14ClF7O2 O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4- organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes with Negative RMS: Germany Tefluthrin (Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin 09Dec2010 2010 doi:10.2903/j.efsa.2010.1709
+Fipronil 120068-37-3 single chemical entity Component is identical to the substance Fipronil 120068-37-3 5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethylsulfinyl) pyrazole-3-carbonitrile Fipronil C12H4Cl2F6N4OS C1=C(C=C(C(=C1Cl)N2C(=C(C(=N2)C#N)S(=O)C(F)(F)F)N)Cl)C(F)(F)F InChI=1S/C12H4Cl2F6N4OS/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)26(25)12(18,19)20/h1-2H,22H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is identical to the substance Fipronil 120068-37-3 5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethylsulfinyl) pyrazole-3-carbonitrile Fipronil C12H4Cl2F6N4OS C1=C(C=C(C(=C1Cl)N2C(=C(C(=N2)C#N)S(=O)C(F)(F)F)N)Cl)C(F)(F)F InChI=1S/C12H4Cl2F6N4OS/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)26(25)12(18,19)20/h1-2H,22H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is identical to the substance Fipronil 120068-37-3 5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethylsulfinyl) pyrazole-3-carbonitrile Fipronil C12H4Cl2F6N4OS C1=C(C=C(C(=C1Cl)N2C(=C(C(=N2)C#N)S(=O)C(F)(F)F)N)Cl)C(F)(F)F InChI=1S/C12H4Cl2F6N4OS/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)26(25)12(18,19)20/h1-2H,22H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is identical to the substance Fipronil 120068-37-3 5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethylsulfinyl) pyrazole-3-carbonitrile Fipronil C12H4Cl2F6N4OS C1=C(C=C(C(=C1Cl)N2C(=C(C(=N2)C#N)S(=O)C(F)(F)F)N)Cl)C(F)(F)F InChI=1S/C12H4Cl2F6N4OS/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)26(25)12(18,19)20/h1-2H,22H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is identical to the substance Fipronil 120068-37-3 5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethylsulfinyl) pyrazole-3-carbonitrile Fipronil C12H4Cl2F6N4OS C1=C(C=C(C(=C1Cl)N2C(=C(C(=N2)C#N)S(=O)C(F)(F)F)N)Cl)C(F)(F)F InChI=1S/C12H4Cl2F6N4OS/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)26(25)12(18,19)20/h1-2H,22H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is identical to the substance Fipronil 120068-37-3 5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethylsulfinyl) pyrazole-3-carbonitrile Fipronil C12H4Cl2F6N4OS C1=C(C=C(C(=C1Cl)N2C(=C(C(=N2)C#N)S(=O)C(F)(F)F)N)Cl)C(F)(F)F InChI=1S/C12H4Cl2F6N4OS/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)26(25)12(18,19)20/h1-2H,22H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is identical to the substance Fipronil 120068-37-3 5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethylsulfinyl) pyrazole-3-carbonitrile Fipronil C12H4Cl2F6N4OS C1=C(C=C(C(=C1Cl)N2C(=C(C(=N2)C#N)S(=O)C(F)(F)F)N)Cl)C(F)(F)F InChI=1S/C12H4Cl2F6N4OS/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)26(25)12(18,19)20/h1-2H,22H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is identical to the substance Fipronil 120068-37-3 5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethylsulfinyl) pyrazole-3-carbonitrile Fipronil C12H4Cl2F6N4OS C1=C(C=C(C(=C1Cl)N2C(=C(C(=N2)C#N)S(=O)C(F)(F)F)N)Cl)C(F)(F)F InChI=1S/C12H4Cl2F6N4OS/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)26(25)12(18,19)20/h1-2H,22H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is identical to the substance Fipronil 120068-37-3 5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethylsulfinyl) pyrazole-3-carbonitrile Fipronil C12H4Cl2F6N4OS C1=C(C=C(C(=C1Cl)N2C(=C(C(=N2)C#N)S(=O)C(F)(F)F)N)Cl)C(F)(F)F InChI=1S/C12H4Cl2F6N4OS/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)26(25)12(18,19)20/h1-2H,22H2 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is identical to the substance Fipronil 120068-37-3 5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethylsulfinyl) pyrazole-3-carbonitrile Fipronil C12H4Cl2F6N4OS C1=C(C=C(C(=C1Cl)N2C(=C(C(=N2)C#N)S(=O)C(F)(F)F)N)Cl)C(F)(F)F InChI=1S/C12H4Cl2F6N4OS/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)26(25)12(18,19)20/h1-2H,22H2 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is identical to the substance Fipronil 120068-37-3 5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethylsulfinyl) pyrazole-3-carbonitrile Fipronil C12H4Cl2F6N4OS C1=C(C=C(C(=C1Cl)N2C(=C(C(=N2)C#N)S(=O)C(F)(F)F)N)Cl)C(F)(F)F InChI=1S/C12H4Cl2F6N4OS/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)26(25)12(18,19)20/h1-2H,22H2 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Inconclusive RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is identical to the substance Fipronil 120068-37-3 5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethylsulfinyl) pyrazole-3-carbonitrile Fipronil C12H4Cl2F6N4OS C1=C(C=C(C(=C1Cl)N2C(=C(C(=N2)C#N)S(=O)C(F)(F)F)N)Cl)C(F)(F)F InChI=1S/C12H4Cl2F6N4OS/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)26(25)12(18,19)20/h1-2H,22H2 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Inconclusive RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is identical to the substance Fipronil 120068-37-3 5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethylsulfinyl) pyrazole-3-carbonitrile Fipronil C12H4Cl2F6N4OS C1=C(C=C(C(=C1Cl)N2C(=C(C(=N2)C#N)S(=O)C(F)(F)F)N)Cl)C(F)(F)F InChI=1S/C12H4Cl2F6N4OS/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)26(25)12(18,19)20/h1-2H,22H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is identical to the substance Fipronil 120068-37-3 5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethylsulfinyl) pyrazole-3-carbonitrile Fipronil C12H4Cl2F6N4OS C1=C(C=C(C(=C1Cl)N2C(=C(C(=N2)C#N)S(=O)C(F)(F)F)N)Cl)C(F)(F)F InChI=1S/C12H4Cl2F6N4OS/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)26(25)12(18,19)20/h1-2H,22H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is identical to the substance Fipronil 120068-37-3 5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethylsulfinyl) pyrazole-3-carbonitrile Fipronil C12H4Cl2F6N4OS C1=C(C=C(C(=C1Cl)N2C(=C(C(=N2)C#N)S(=O)C(F)(F)F)N)Cl)C(F)(F)F InChI=1S/C12H4Cl2F6N4OS/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)26(25)12(18,19)20/h1-2H,22H2 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 72.0000000000 h yes not applicable Negative no evidence RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is identical to the substance Fipronil 120068-37-3 5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethylsulfinyl) pyrazole-3-carbonitrile Fipronil C12H4Cl2F6N4OS C1=C(C=C(C(=C1Cl)N2C(=C(C(=N2)C#N)S(=O)C(F)(F)F)N)Cl)C(F)(F)F InChI=1S/C12H4Cl2F6N4OS/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)26(25)12(18,19)20/h1-2H,22H2 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 48.0000000000 h yes not applicable Negative no evidence RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is identical to the substance Fipronil 120068-37-3 5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethylsulfinyl) pyrazole-3-carbonitrile Fipronil C12H4Cl2F6N4OS C1=C(C=C(C(=C1Cl)N2C(=C(C(=N2)C#N)S(=O)C(F)(F)F)N)Cl)C(F)(F)F InChI=1S/C12H4Cl2F6N4OS/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)26(25)12(18,19)20/h1-2H,22H2 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes not applicable Negative no evidence RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is identical to the substance Fipronil 120068-37-3 5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethylsulfinyl) pyrazole-3-carbonitrile Fipronil C12H4Cl2F6N4OS C1=C(C=C(C(=C1Cl)N2C(=C(C(=N2)C#N)S(=O)C(F)(F)F)N)Cl)C(F)(F)F InChI=1S/C12H4Cl2F6N4OS/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)26(25)12(18,19)20/h1-2H,22H2 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 48.0000000000 h yes not applicable Negative no evidence RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is identical to the substance Fipronil 120068-37-3 5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethylsulfinyl) pyrazole-3-carbonitrile Fipronil C12H4Cl2F6N4OS C1=C(C=C(C(=C1Cl)N2C(=C(C(=N2)C#N)S(=O)C(F)(F)F)N)Cl)C(F)(F)F InChI=1S/C12H4Cl2F6N4OS/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)26(25)12(18,19)20/h1-2H,22H2 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes not applicable Negative no evidence RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is identical to the substance Fipronil 120068-37-3 5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethylsulfinyl) pyrazole-3-carbonitrile Fipronil C12H4Cl2F6N4OS C1=C(C=C(C(=C1Cl)N2C(=C(C(=N2)C#N)S(=O)C(F)(F)F)N)Cl)C(F)(F)F InChI=1S/C12H4Cl2F6N4OS/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)26(25)12(18,19)20/h1-2H,22H2 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 72.0000000000 h yes not applicable Negative no evidence RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is identical to the substance Fipronil 120068-37-3 5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethylsulfinyl) pyrazole-3-carbonitrile Fipronil C12H4Cl2F6N4OS C1=C(C=C(C(=C1Cl)N2C(=C(C(=N2)C#N)S(=O)C(F)(F)F)N)Cl)C(F)(F)F InChI=1S/C12H4Cl2F6N4OS/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)26(25)12(18,19)20/h1-2H,22H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: France Fipronil (Final addendum) 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is identical to the substance Fipronil 120068-37-3 5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethylsulfinyl) pyrazole-3-carbonitrile Fipronil C12H4Cl2F6N4OS C1=C(C=C(C(=C1Cl)N2C(=C(C(=N2)C#N)S(=O)C(F)(F)F)N)Cl)C(F)(F)F InChI=1S/C12H4Cl2F6N4OS/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)26(25)12(18,19)20/h1-2H,22H2 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: France Fipronil (Final addendum) 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is identical to the substance Fipronil 120068-37-3 5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethylsulfinyl) pyrazole-3-carbonitrile Fipronil C12H4Cl2F6N4OS C1=C(C=C(C(=C1Cl)N2C(=C(C(=N2)C#N)S(=O)C(F)(F)F)N)Cl)C(F)(F)F InChI=1S/C12H4Cl2F6N4OS/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)26(25)12(18,19)20/h1-2H,22H2 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Wistar 3 Male oral: gavage 14.0000000000 h yes, concurrent vehicle not applicable Negative RMS: France Fipronil (Final addendum) 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is identical to the substance Fipronil 120068-37-3 5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethylsulfinyl) pyrazole-3-carbonitrile Fipronil C12H4Cl2F6N4OS C1=C(C=C(C(=C1Cl)N2C(=C(C(=N2)C#N)S(=O)C(F)(F)F)N)Cl)C(F)(F)F InChI=1S/C12H4Cl2F6N4OS/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)26(25)12(18,19)20/h1-2H,22H2 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Wistar 3 Male oral: gavage 3.0000000000 h yes, concurrent vehicle not applicable Negative RMS: France Fipronil (Final addendum) 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile 5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile Not in list C12H4Cl2F6N4S FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(SC(F)(F)F)c1N)c(Cl)c2 InChI=1/C12H4Cl2F6N4S/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)25-12(18,19)20/h1-2H,22H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile 5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile Not in list C12H4Cl2F6N4S FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(SC(F)(F)F)c1N)c(Cl)c2 InChI=1/C12H4Cl2F6N4S/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)25-12(18,19)20/h1-2H,22H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile 5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile Not in list C12H4Cl2F6N4S FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(SC(F)(F)F)c1N)c(Cl)c2 InChI=1/C12H4Cl2F6N4S/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)25-12(18,19)20/h1-2H,22H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile 5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile Not in list C12H4Cl2F6N4S FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(SC(F)(F)F)c1N)c(Cl)c2 InChI=1/C12H4Cl2F6N4S/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)25-12(18,19)20/h1-2H,22H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile 5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile Not in list C12H4Cl2F6N4S FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(SC(F)(F)F)c1N)c(Cl)c2 InChI=1/C12H4Cl2F6N4S/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)25-12(18,19)20/h1-2H,22H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile 5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile Not in list C12H4Cl2F6N4S FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(SC(F)(F)F)c1N)c(Cl)c2 InChI=1/C12H4Cl2F6N4S/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)25-12(18,19)20/h1-2H,22H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile 5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile Not in list C12H4Cl2F6N4S FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(SC(F)(F)F)c1N)c(Cl)c2 InChI=1/C12H4Cl2F6N4S/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)25-12(18,19)20/h1-2H,22H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile 5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile Not in list C12H4Cl2F6N4S FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(SC(F)(F)F)c1N)c(Cl)c2 InChI=1/C12H4Cl2F6N4S/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)25-12(18,19)20/h1-2H,22H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile 5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile Not in list C12H4Cl2F6N4S FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(SC(F)(F)F)c1N)c(Cl)c2 InChI=1/C12H4Cl2F6N4S/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)25-12(18,19)20/h1-2H,22H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile 5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile Not in list C12H4Cl2F6N4S FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(SC(F)(F)F)c1N)c(Cl)c2 InChI=1/C12H4Cl2F6N4S/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)25-12(18,19)20/h1-2H,22H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile 5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile Not in list C12H4Cl2F6N4S FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(SC(F)(F)F)c1N)c(Cl)c2 InChI=1/C12H4Cl2F6N4S/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)25-12(18,19)20/h1-2H,22H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile 5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile Not in list C12H4Cl2F6N4S FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(SC(F)(F)F)c1N)c(Cl)c2 InChI=1/C12H4Cl2F6N4S/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)25-12(18,19)20/h1-2H,22H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile 5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile Not in list C12H4Cl2F6N4S FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(SC(F)(F)F)c1N)c(Cl)c2 InChI=1/C12H4Cl2F6N4S/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)25-12(18,19)20/h1-2H,22H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile 5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile Not in list C12H4Cl2F6N4S FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(SC(F)(F)F)c1N)c(Cl)c2 InChI=1/C12H4Cl2F6N4S/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)25-12(18,19)20/h1-2H,22H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile 5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile Not in list C12H4Cl2F6N4S FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(SC(F)(F)F)c1N)c(Cl)c2 InChI=1/C12H4Cl2F6N4S/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)25-12(18,19)20/h1-2H,22H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile 5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile Not in list C12H4Cl2F6N4S FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(SC(F)(F)F)c1N)c(Cl)c2 InChI=1/C12H4Cl2F6N4S/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)25-12(18,19)20/h1-2H,22H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile 5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile Not in list C12H4Cl2F6N4S FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(SC(F)(F)F)c1N)c(Cl)c2 InChI=1/C12H4Cl2F6N4S/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)25-12(18,19)20/h1-2H,22H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile 5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile Not in list C12H4Cl2F6N4S FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(SC(F)(F)F)c1N)c(Cl)c2 InChI=1/C12H4Cl2F6N4S/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)25-12(18,19)20/h1-2H,22H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile 5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile Not in list C12H4Cl2F6N4S FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(SC(F)(F)F)c1N)c(Cl)c2 InChI=1/C12H4Cl2F6N4S/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)25-12(18,19)20/h1-2H,22H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile 5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile Not in list C12H4Cl2F6N4S FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(SC(F)(F)F)c1N)c(Cl)c2 InChI=1/C12H4Cl2F6N4S/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)25-12(18,19)20/h1-2H,22H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile 5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile Not in list C12H4Cl2F6N4S FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(SC(F)(F)F)c1N)c(Cl)c2 InChI=1/C12H4Cl2F6N4S/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)25-12(18,19)20/h1-2H,22H2 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile 5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile Not in list C12H4Cl2F6N4S FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(SC(F)(F)F)c1N)c(Cl)c2 InChI=1/C12H4Cl2F6N4S/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)25-12(18,19)20/h1-2H,22H2 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-Amino-1-(2,6-dichloro-alpha,alpha,alpha-trifluoro-p-tolyl)-4-trifluoro-methylsulfonylpyrazole-3-carbonitrile 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfonyl]-1H-pyrazole-3-carbonitrile Not in list C12H4Cl2F6N4O2S FC(F)(F)S(=O)(=O)c1c(N)n(nc1C#N)c2c(Cl)cc(cc2Cl)C(F)(F)F InChI=1S/C12H4Cl2F6N4O2S/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)27(25,26)12(18,19)20/h1-2H,22H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-Amino-1-(2,6-dichloro-alpha,alpha,alpha-trifluoro-p-tolyl)-4-trifluoro-methylsulfonylpyrazole-3-carbonitrile 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfonyl]-1H-pyrazole-3-carbonitrile Not in list C12H4Cl2F6N4O2S FC(F)(F)S(=O)(=O)c1c(N)n(nc1C#N)c2c(Cl)cc(cc2Cl)C(F)(F)F InChI=1S/C12H4Cl2F6N4O2S/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)27(25,26)12(18,19)20/h1-2H,22H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-Amino-1-(2,6-dichloro-alpha,alpha,alpha-trifluoro-p-tolyl)-4-trifluoro-methylsulfonylpyrazole-3-carbonitrile 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfonyl]-1H-pyrazole-3-carbonitrile Not in list C12H4Cl2F6N4O2S FC(F)(F)S(=O)(=O)c1c(N)n(nc1C#N)c2c(Cl)cc(cc2Cl)C(F)(F)F InChI=1S/C12H4Cl2F6N4O2S/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)27(25,26)12(18,19)20/h1-2H,22H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-Amino-1-(2,6-dichloro-alpha,alpha,alpha-trifluoro-p-tolyl)-4-trifluoro-methylsulfonylpyrazole-3-carbonitrile 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfonyl]-1H-pyrazole-3-carbonitrile Not in list C12H4Cl2F6N4O2S FC(F)(F)S(=O)(=O)c1c(N)n(nc1C#N)c2c(Cl)cc(cc2Cl)C(F)(F)F InChI=1S/C12H4Cl2F6N4O2S/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)27(25,26)12(18,19)20/h1-2H,22H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-Amino-1-(2,6-dichloro-alpha,alpha,alpha-trifluoro-p-tolyl)-4-trifluoro-methylsulfonylpyrazole-3-carbonitrile 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfonyl]-1H-pyrazole-3-carbonitrile Not in list C12H4Cl2F6N4O2S FC(F)(F)S(=O)(=O)c1c(N)n(nc1C#N)c2c(Cl)cc(cc2Cl)C(F)(F)F InChI=1S/C12H4Cl2F6N4O2S/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)27(25,26)12(18,19)20/h1-2H,22H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-Amino-1-(2,6-dichloro-alpha,alpha,alpha-trifluoro-p-tolyl)-4-trifluoro-methylsulfonylpyrazole-3-carbonitrile 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfonyl]-1H-pyrazole-3-carbonitrile Not in list C12H4Cl2F6N4O2S FC(F)(F)S(=O)(=O)c1c(N)n(nc1C#N)c2c(Cl)cc(cc2Cl)C(F)(F)F InChI=1S/C12H4Cl2F6N4O2S/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)27(25,26)12(18,19)20/h1-2H,22H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-Amino-1-(2,6-dichloro-alpha,alpha,alpha-trifluoro-p-tolyl)-4-trifluoro-methylsulfonylpyrazole-3-carbonitrile 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfonyl]-1H-pyrazole-3-carbonitrile Not in list C12H4Cl2F6N4O2S FC(F)(F)S(=O)(=O)c1c(N)n(nc1C#N)c2c(Cl)cc(cc2Cl)C(F)(F)F InChI=1S/C12H4Cl2F6N4O2S/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)27(25,26)12(18,19)20/h1-2H,22H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-Amino-1-(2,6-dichloro-alpha,alpha,alpha-trifluoro-p-tolyl)-4-trifluoro-methylsulfonylpyrazole-3-carbonitrile 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfonyl]-1H-pyrazole-3-carbonitrile Not in list C12H4Cl2F6N4O2S FC(F)(F)S(=O)(=O)c1c(N)n(nc1C#N)c2c(Cl)cc(cc2Cl)C(F)(F)F InChI=1S/C12H4Cl2F6N4O2S/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)27(25,26)12(18,19)20/h1-2H,22H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-Amino-1-(2,6-dichloro-alpha,alpha,alpha-trifluoro-p-tolyl)-4-trifluoro-methylsulfonylpyrazole-3-carbonitrile 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfonyl]-1H-pyrazole-3-carbonitrile Not in list C12H4Cl2F6N4O2S FC(F)(F)S(=O)(=O)c1c(N)n(nc1C#N)c2c(Cl)cc(cc2Cl)C(F)(F)F InChI=1S/C12H4Cl2F6N4O2S/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)27(25,26)12(18,19)20/h1-2H,22H2 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-Amino-1-(2,6-dichloro-alpha,alpha,alpha-trifluoro-p-tolyl)-4-trifluoro-methylsulfonylpyrazole-3-carbonitrile 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfonyl]-1H-pyrazole-3-carbonitrile Not in list C12H4Cl2F6N4O2S FC(F)(F)S(=O)(=O)c1c(N)n(nc1C#N)c2c(Cl)cc(cc2Cl)C(F)(F)F InChI=1S/C12H4Cl2F6N4O2S/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)27(25,26)12(18,19)20/h1-2H,22H2 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) hepatocytes Not reported yes, concurrent vehicle with Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-Amino-1-(2,6-dichloro-alpha,alpha,alpha-trifluoro-p-tolyl)-4-trifluoro-methylpyrazole-3-carbonitrile 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethyl)-1H-pyrazole-3-carbonitrile Not in list C12H4Cl2F6N4 FC(F)(F)c1cc(Cl)c(c(Cl)c1)n2nc(C#N)c(c2N)C(F)(F)F InChI=1S/C12H4Cl2F6N4/c13-5-1-4(11(15,16)17)2-6(14)9(5)24-10(22)8(12(18,19)20)7(3-21)23-24/h1-2H,22H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-Amino-1-(2,6-dichloro-alpha,alpha,alpha-trifluoro-p-tolyl)-4-trifluoro-methylpyrazole-3-carbonitrile 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethyl)-1H-pyrazole-3-carbonitrile Not in list C12H4Cl2F6N4 FC(F)(F)c1cc(Cl)c(c(Cl)c1)n2nc(C#N)c(c2N)C(F)(F)F InChI=1S/C12H4Cl2F6N4/c13-5-1-4(11(15,16)17)2-6(14)9(5)24-10(22)8(12(18,19)20)7(3-21)23-24/h1-2H,22H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-Amino-1-(2,6-dichloro-alpha,alpha,alpha-trifluoro-p-tolyl)-4-trifluoro-methylpyrazole-3-carbonitrile 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethyl)-1H-pyrazole-3-carbonitrile Not in list C12H4Cl2F6N4 FC(F)(F)c1cc(Cl)c(c(Cl)c1)n2nc(C#N)c(c2N)C(F)(F)F InChI=1S/C12H4Cl2F6N4/c13-5-1-4(11(15,16)17)2-6(14)9(5)24-10(22)8(12(18,19)20)7(3-21)23-24/h1-2H,22H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-Amino-1-(2,6-dichloro-alpha,alpha,alpha-trifluoro-p-tolyl)-4-trifluoro-methylpyrazole-3-carbonitrile 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethyl)-1H-pyrazole-3-carbonitrile Not in list C12H4Cl2F6N4 FC(F)(F)c1cc(Cl)c(c(Cl)c1)n2nc(C#N)c(c2N)C(F)(F)F InChI=1S/C12H4Cl2F6N4/c13-5-1-4(11(15,16)17)2-6(14)9(5)24-10(22)8(12(18,19)20)7(3-21)23-24/h1-2H,22H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-Amino-1-(2,6-dichloro-alpha,alpha,alpha-trifluoro-p-tolyl)-4-trifluoro-methylpyrazole-3-carbonitrile 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethyl)-1H-pyrazole-3-carbonitrile Not in list C12H4Cl2F6N4 FC(F)(F)c1cc(Cl)c(c(Cl)c1)n2nc(C#N)c(c2N)C(F)(F)F InChI=1S/C12H4Cl2F6N4/c13-5-1-4(11(15,16)17)2-6(14)9(5)24-10(22)8(12(18,19)20)7(3-21)23-24/h1-2H,22H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-Amino-1-(2,6-dichloro-alpha,alpha,alpha-trifluoro-p-tolyl)-4-trifluoro-methylpyrazole-3-carbonitrile 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethyl)-1H-pyrazole-3-carbonitrile Not in list C12H4Cl2F6N4 FC(F)(F)c1cc(Cl)c(c(Cl)c1)n2nc(C#N)c(c2N)C(F)(F)F InChI=1S/C12H4Cl2F6N4/c13-5-1-4(11(15,16)17)2-6(14)9(5)24-10(22)8(12(18,19)20)7(3-21)23-24/h1-2H,22H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-Amino-1-(2,6-dichloro-alpha,alpha,alpha-trifluoro-p-tolyl)-4-trifluoro-methylpyrazole-3-carbonitrile 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethyl)-1H-pyrazole-3-carbonitrile Not in list C12H4Cl2F6N4 FC(F)(F)c1cc(Cl)c(c(Cl)c1)n2nc(C#N)c(c2N)C(F)(F)F InChI=1S/C12H4Cl2F6N4/c13-5-1-4(11(15,16)17)2-6(14)9(5)24-10(22)8(12(18,19)20)7(3-21)23-24/h1-2H,22H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-Amino-1-(2,6-dichloro-alpha,alpha,alpha-trifluoro-p-tolyl)-4-trifluoro-methylpyrazole-3-carbonitrile 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethyl)-1H-pyrazole-3-carbonitrile Not in list C12H4Cl2F6N4 FC(F)(F)c1cc(Cl)c(c(Cl)c1)n2nc(C#N)c(c2N)C(F)(F)F InChI=1S/C12H4Cl2F6N4/c13-5-1-4(11(15,16)17)2-6(14)9(5)24-10(22)8(12(18,19)20)7(3-21)23-24/h1-2H,22H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-Amino-1-(2,6-dichloro-alpha,alpha,alpha-trifluoro-p-tolyl)-4-trifluoro-methylpyrazole-3-carbonitrile 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethyl)-1H-pyrazole-3-carbonitrile Not in list C12H4Cl2F6N4 FC(F)(F)c1cc(Cl)c(c(Cl)c1)n2nc(C#N)c(c2N)C(F)(F)F InChI=1S/C12H4Cl2F6N4/c13-5-1-4(11(15,16)17)2-6(14)9(5)24-10(22)8(12(18,19)20)7(3-21)23-24/h1-2H,22H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-Amino-1-(2,6-dichloro-alpha,alpha,alpha-trifluoro-p-tolyl)-4-trifluoro-methylpyrazole-3-carbonitrile 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethyl)-1H-pyrazole-3-carbonitrile Not in list C12H4Cl2F6N4 FC(F)(F)c1cc(Cl)c(c(Cl)c1)n2nc(C#N)c(c2N)C(F)(F)F InChI=1S/C12H4Cl2F6N4/c13-5-1-4(11(15,16)17)2-6(14)9(5)24-10(22)8(12(18,19)20)7(3-21)23-24/h1-2H,22H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-Amino-1-(2,6-dichloro-alpha,alpha,alpha-trifluoro-p-tolyl)-4-trifluoro-methylpyrazole-3-carbonitrile 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethyl)-1H-pyrazole-3-carbonitrile Not in list C12H4Cl2F6N4 FC(F)(F)c1cc(Cl)c(c(Cl)c1)n2nc(C#N)c(c2N)C(F)(F)F InChI=1S/C12H4Cl2F6N4/c13-5-1-4(11(15,16)17)2-6(14)9(5)24-10(22)8(12(18,19)20)7(3-21)23-24/h1-2H,22H2 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-Amino-1-(2,6-dichloro-alpha,alpha,alpha-trifluoro-p-tolyl)-4-trifluoro-methylpyrazole-3-carbonitrile 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethyl)-1H-pyrazole-3-carbonitrile Not in list C12H4Cl2F6N4 FC(F)(F)c1cc(Cl)c(c(Cl)c1)n2nc(C#N)c(c2N)C(F)(F)F InChI=1S/C12H4Cl2F6N4/c13-5-1-4(11(15,16)17)2-6(14)9(5)24-10(22)8(12(18,19)20)7(3-21)23-24/h1-2H,22H2 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-Amino-1-(2,6-dichloro-alpha,alpha,alpha-trifluoro-p-tolyl)-4-trifluoro-methylpyrazole-3-carbonitrile 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethyl)-1H-pyrazole-3-carbonitrile Not in list C12H4Cl2F6N4 FC(F)(F)c1cc(Cl)c(c(Cl)c1)n2nc(C#N)c(c2N)C(F)(F)F InChI=1S/C12H4Cl2F6N4/c13-5-1-4(11(15,16)17)2-6(14)9(5)24-10(22)8(12(18,19)20)7(3-21)23-24/h1-2H,22H2 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-Amino-1-(2,6-dichloro-alpha,alpha,alpha-trifluoro-p-tolyl)-4-trifluoro-methylpyrazole-3-carbonitrile 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethyl)-1H-pyrazole-3-carbonitrile Not in list C12H4Cl2F6N4 FC(F)(F)c1cc(Cl)c(c(Cl)c1)n2nc(C#N)c(c2N)C(F)(F)F InChI=1S/C12H4Cl2F6N4/c13-5-1-4(11(15,16)17)2-6(14)9(5)24-10(22)8(12(18,19)20)7(3-21)23-24/h1-2H,22H2 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-Amino-1-(2,6-dichloro-alpha,alpha,alpha-trifluoro-p-tolyl)-4-trifluoro-methylpyrazole-3-carbonitrile 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethyl)-1H-pyrazole-3-carbonitrile Not in list C12H4Cl2F6N4 FC(F)(F)c1cc(Cl)c(c(Cl)c1)n2nc(C#N)c(c2N)C(F)(F)F InChI=1S/C12H4Cl2F6N4/c13-5-1-4(11(15,16)17)2-6(14)9(5)24-10(22)8(12(18,19)20)7(3-21)23-24/h1-2H,22H2 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 72.0000000000 h yes not applicable Negative direct evidence-cytotoxicity RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-Amino-1-(2,6-dichloro-alpha,alpha,alpha-trifluoro-p-tolyl)-4-trifluoro-methylpyrazole-3-carbonitrile 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethyl)-1H-pyrazole-3-carbonitrile Not in list C12H4Cl2F6N4 FC(F)(F)c1cc(Cl)c(c(Cl)c1)n2nc(C#N)c(c2N)C(F)(F)F InChI=1S/C12H4Cl2F6N4/c13-5-1-4(11(15,16)17)2-6(14)9(5)24-10(22)8(12(18,19)20)7(3-21)23-24/h1-2H,22H2 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 48.0000000000 h yes not applicable Negative direct evidence-cytotoxicity RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-Amino-1-(2,6-dichloro-alpha,alpha,alpha-trifluoro-p-tolyl)-4-trifluoro-methylpyrazole-3-carbonitrile 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethyl)-1H-pyrazole-3-carbonitrile Not in list C12H4Cl2F6N4 FC(F)(F)c1cc(Cl)c(c(Cl)c1)n2nc(C#N)c(c2N)C(F)(F)F InChI=1S/C12H4Cl2F6N4/c13-5-1-4(11(15,16)17)2-6(14)9(5)24-10(22)8(12(18,19)20)7(3-21)23-24/h1-2H,22H2 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes not applicable Negative direct evidence-cytotoxicity RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl) pyrazole-4-sulfonic acid, potassium salt 5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl) pyrazole-4-sulfonic acid Not in list C11H5Cl2F3N4O3S FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(c1N)S(O)(=O)=O)c(Cl)c2 InChI=1/C11H5Cl2F3N4O3S/c12-5-1-4(11(14,15)16)2-6(13)8(5)20-10(18)9(24(21,22)23)7(3-17)19-20/h1-2H,18H2,(H,21,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl) pyrazole-4-sulfonic acid, potassium salt 5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl) pyrazole-4-sulfonic acid Not in list C11H5Cl2F3N4O3S FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(c1N)S(O)(=O)=O)c(Cl)c2 InChI=1/C11H5Cl2F3N4O3S/c12-5-1-4(11(14,15)16)2-6(13)8(5)20-10(18)9(24(21,22)23)7(3-17)19-20/h1-2H,18H2,(H,21,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl) pyrazole-4-sulfonic acid, potassium salt 5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl) pyrazole-4-sulfonic acid Not in list C11H5Cl2F3N4O3S FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(c1N)S(O)(=O)=O)c(Cl)c2 InChI=1/C11H5Cl2F3N4O3S/c12-5-1-4(11(14,15)16)2-6(13)8(5)20-10(18)9(24(21,22)23)7(3-17)19-20/h1-2H,18H2,(H,21,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl) pyrazole-4-sulfonic acid, potassium salt 5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl) pyrazole-4-sulfonic acid Not in list C11H5Cl2F3N4O3S FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(c1N)S(O)(=O)=O)c(Cl)c2 InChI=1/C11H5Cl2F3N4O3S/c12-5-1-4(11(14,15)16)2-6(13)8(5)20-10(18)9(24(21,22)23)7(3-17)19-20/h1-2H,18H2,(H,21,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl) pyrazole-4-sulfonic acid, potassium salt 5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl) pyrazole-4-sulfonic acid Not in list C11H5Cl2F3N4O3S FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(c1N)S(O)(=O)=O)c(Cl)c2 InChI=1/C11H5Cl2F3N4O3S/c12-5-1-4(11(14,15)16)2-6(13)8(5)20-10(18)9(24(21,22)23)7(3-17)19-20/h1-2H,18H2,(H,21,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl) pyrazole-4-sulfonic acid, potassium salt 5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl) pyrazole-4-sulfonic acid Not in list C11H5Cl2F3N4O3S FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(c1N)S(O)(=O)=O)c(Cl)c2 InChI=1/C11H5Cl2F3N4O3S/c12-5-1-4(11(14,15)16)2-6(13)8(5)20-10(18)9(24(21,22)23)7(3-17)19-20/h1-2H,18H2,(H,21,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl) pyrazole-4-sulfonic acid, potassium salt 5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl) pyrazole-4-sulfonic acid Not in list C11H5Cl2F3N4O3S FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(c1N)S(O)(=O)=O)c(Cl)c2 InChI=1/C11H5Cl2F3N4O3S/c12-5-1-4(11(14,15)16)2-6(13)8(5)20-10(18)9(24(21,22)23)7(3-17)19-20/h1-2H,18H2,(H,21,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl) pyrazole-4-sulfonic acid, potassium salt 5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl) pyrazole-4-sulfonic acid Not in list C11H5Cl2F3N4O3S FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(c1N)S(O)(=O)=O)c(Cl)c2 InChI=1/C11H5Cl2F3N4O3S/c12-5-1-4(11(14,15)16)2-6(13)8(5)20-10(18)9(24(21,22)23)7(3-17)19-20/h1-2H,18H2,(H,21,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl) pyrazole-4-sulfonic acid, potassium salt 5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl) pyrazole-4-sulfonic acid Not in list C11H5Cl2F3N4O3S FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(c1N)S(O)(=O)=O)c(Cl)c2 InChI=1/C11H5Cl2F3N4O3S/c12-5-1-4(11(14,15)16)2-6(13)8(5)20-10(18)9(24(21,22)23)7(3-17)19-20/h1-2H,18H2,(H,21,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl) pyrazole-4-sulfonic acid, potassium salt 5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl) pyrazole-4-sulfonic acid Not in list C11H5Cl2F3N4O3S FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(c1N)S(O)(=O)=O)c(Cl)c2 InChI=1/C11H5Cl2F3N4O3S/c12-5-1-4(11(14,15)16)2-6(13)8(5)20-10(18)9(24(21,22)23)7(3-17)19-20/h1-2H,18H2,(H,21,22,23) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl) pyrazole-4-sulfonic acid, potassium salt 5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl) pyrazole-4-sulfonic acid Not in list C11H5Cl2F3N4O3S FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(c1N)S(O)(=O)=O)c(Cl)c2 InChI=1/C11H5Cl2F3N4O3S/c12-5-1-4(11(14,15)16)2-6(13)8(5)20-10(18)9(24(21,22)23)7(3-17)19-20/h1-2H,18H2,(H,21,22,23) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl) pyrazole-4-sulfonic acid, potassium salt 5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl) pyrazole-4-sulfonic acid Not in list C11H5Cl2F3N4O3S FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(c1N)S(O)(=O)=O)c(Cl)c2 InChI=1/C11H5Cl2F3N4O3S/c12-5-1-4(11(14,15)16)2-6(13)8(5)20-10(18)9(24(21,22)23)7(3-17)19-20/h1-2H,18H2,(H,21,22,23) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-Amino-1-(2,6-dichloro-4-trifluoromethylphenyl)-4-trifluoromethylsulfonylpyrazole-3-carboxylic acid 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfonyl]-1H-pyrazole-3-carboxylic acid Not in list C12H5Cl2F6N3O3S FC(F)(F)S(=O)c2c(nn(c1c(Cl)cc(cc1Cl)C(F)(F)F)c2N)C(O)=O InChI=1S/C12H5Cl2F6N3O4S/c13-4-1-3(11(15,16)17)2-5(14)7(4)23-9(21)8(6(22-23)10(24)25)28(26,27)12(18,19)20/h1-2H,21H2,(H,24,25) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-Amino-1-(2,6-dichloro-4-trifluoromethylphenyl)-4-trifluoromethylsulfonylpyrazole-3-carboxylic acid 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfonyl]-1H-pyrazole-3-carboxylic acid Not in list C12H5Cl2F6N3O3S FC(F)(F)S(=O)c2c(nn(c1c(Cl)cc(cc1Cl)C(F)(F)F)c2N)C(O)=O InChI=1S/C12H5Cl2F6N3O4S/c13-4-1-3(11(15,16)17)2-5(14)7(4)23-9(21)8(6(22-23)10(24)25)28(26,27)12(18,19)20/h1-2H,21H2,(H,24,25) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-Amino-1-(2,6-dichloro-4-trifluoromethylphenyl)-4-trifluoromethylsulfonylpyrazole-3-carboxylic acid 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfonyl]-1H-pyrazole-3-carboxylic acid Not in list C12H5Cl2F6N3O3S FC(F)(F)S(=O)c2c(nn(c1c(Cl)cc(cc1Cl)C(F)(F)F)c2N)C(O)=O InChI=1S/C12H5Cl2F6N3O4S/c13-4-1-3(11(15,16)17)2-5(14)7(4)23-9(21)8(6(22-23)10(24)25)28(26,27)12(18,19)20/h1-2H,21H2,(H,24,25) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-Amino-1-(2,6-dichloro-4-trifluoromethylphenyl)-4-trifluoromethylsulfonylpyrazole-3-carboxylic acid 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfonyl]-1H-pyrazole-3-carboxylic acid Not in list C12H5Cl2F6N3O3S FC(F)(F)S(=O)c2c(nn(c1c(Cl)cc(cc1Cl)C(F)(F)F)c2N)C(O)=O InChI=1S/C12H5Cl2F6N3O4S/c13-4-1-3(11(15,16)17)2-5(14)7(4)23-9(21)8(6(22-23)10(24)25)28(26,27)12(18,19)20/h1-2H,21H2,(H,24,25) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-Amino-1-(2,6-dichloro-4-trifluoromethylphenyl)-4-trifluoromethylsulfonylpyrazole-3-carboxylic acid 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfonyl]-1H-pyrazole-3-carboxylic acid Not in list C12H5Cl2F6N3O3S FC(F)(F)S(=O)c2c(nn(c1c(Cl)cc(cc1Cl)C(F)(F)F)c2N)C(O)=O InChI=1S/C12H5Cl2F6N3O4S/c13-4-1-3(11(15,16)17)2-5(14)7(4)23-9(21)8(6(22-23)10(24)25)28(26,27)12(18,19)20/h1-2H,21H2,(H,24,25) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-Amino-1-(2,6-dichloro-4-trifluoromethylphenyl)-4-trifluoromethylsulfonylpyrazole-3-carboxylic acid 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfonyl]-1H-pyrazole-3-carboxylic acid Not in list C12H5Cl2F6N3O3S FC(F)(F)S(=O)c2c(nn(c1c(Cl)cc(cc1Cl)C(F)(F)F)c2N)C(O)=O InChI=1S/C12H5Cl2F6N3O4S/c13-4-1-3(11(15,16)17)2-5(14)7(4)23-9(21)8(6(22-23)10(24)25)28(26,27)12(18,19)20/h1-2H,21H2,(H,24,25) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-Amino-1-(2,6-dichloro-4-trifluoromethylphenyl)-4-trifluoromethylsulfonylpyrazole-3-carboxylic acid 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfonyl]-1H-pyrazole-3-carboxylic acid Not in list C12H5Cl2F6N3O3S FC(F)(F)S(=O)c2c(nn(c1c(Cl)cc(cc1Cl)C(F)(F)F)c2N)C(O)=O InChI=1S/C12H5Cl2F6N3O4S/c13-4-1-3(11(15,16)17)2-5(14)7(4)23-9(21)8(6(22-23)10(24)25)28(26,27)12(18,19)20/h1-2H,21H2,(H,24,25) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-Amino-1-(2,6-dichloro-4-trifluoromethylphenyl)-4-trifluoromethylsulfonylpyrazole-3-carboxylic acid 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfonyl]-1H-pyrazole-3-carboxylic acid Not in list C12H5Cl2F6N3O3S FC(F)(F)S(=O)c2c(nn(c1c(Cl)cc(cc1Cl)C(F)(F)F)c2N)C(O)=O InChI=1S/C12H5Cl2F6N3O4S/c13-4-1-3(11(15,16)17)2-5(14)7(4)23-9(21)8(6(22-23)10(24)25)28(26,27)12(18,19)20/h1-2H,21H2,(H,24,25) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-Amino-1-(2,6-dichloro-4-trifluoromethylphenyl)-4-trifluoromethylsulfonylpyrazole-3-carboxylic acid 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfonyl]-1H-pyrazole-3-carboxylic acid Not in list C12H5Cl2F6N3O3S FC(F)(F)S(=O)c2c(nn(c1c(Cl)cc(cc1Cl)C(F)(F)F)c2N)C(O)=O InChI=1S/C12H5Cl2F6N3O4S/c13-4-1-3(11(15,16)17)2-5(14)7(4)23-9(21)8(6(22-23)10(24)25)28(26,27)12(18,19)20/h1-2H,21H2,(H,24,25) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-Amino-1-(2,6-dichloro-4-trifluoromethylphenyl)-4-trifluoromethylsulfonylpyrazole-3-carboxylic acid 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfonyl]-1H-pyrazole-3-carboxylic acid Not in list C12H5Cl2F6N3O3S FC(F)(F)S(=O)c2c(nn(c1c(Cl)cc(cc1Cl)C(F)(F)F)c2N)C(O)=O InChI=1S/C12H5Cl2F6N3O4S/c13-4-1-3(11(15,16)17)2-5(14)7(4)23-9(21)8(6(22-23)10(24)25)28(26,27)12(18,19)20/h1-2H,21H2,(H,24,25) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-Amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylsulfonyl-1H-pyrazole-3-carboxamide 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethanesulfinyl)-1H-pyrazole-3-carboxamide Not in list C12H6Cl2F6N4O2S FC(F)(F)S(=O)c1c(N)n(nc1C(N)=O)c2c(Cl)cc(cc2Cl)C(F)(F)F InChI=1/C12H6Cl2F6N4O2S/c13-4-1-3(11(15,16)17)2-5(14)7(4)24-9(21)8(6(23-24)10(22)25)27(26)12(18,19)20/h1-2H,21H2,(H2,22,25)/t27? organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-Amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylsulfonyl-1H-pyrazole-3-carboxamide 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethanesulfinyl)-1H-pyrazole-3-carboxamide Not in list C12H6Cl2F6N4O2S FC(F)(F)S(=O)c1c(N)n(nc1C(N)=O)c2c(Cl)cc(cc2Cl)C(F)(F)F InChI=1/C12H6Cl2F6N4O2S/c13-4-1-3(11(15,16)17)2-5(14)7(4)24-9(21)8(6(23-24)10(22)25)27(26)12(18,19)20/h1-2H,21H2,(H2,22,25)/t27? organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-Amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylsulfonyl-1H-pyrazole-3-carboxamide 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethanesulfinyl)-1H-pyrazole-3-carboxamide Not in list C12H6Cl2F6N4O2S FC(F)(F)S(=O)c1c(N)n(nc1C(N)=O)c2c(Cl)cc(cc2Cl)C(F)(F)F InChI=1/C12H6Cl2F6N4O2S/c13-4-1-3(11(15,16)17)2-5(14)7(4)24-9(21)8(6(23-24)10(22)25)27(26)12(18,19)20/h1-2H,21H2,(H2,22,25)/t27? organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-Amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylsulfonyl-1H-pyrazole-3-carboxamide 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethanesulfinyl)-1H-pyrazole-3-carboxamide Not in list C12H6Cl2F6N4O2S FC(F)(F)S(=O)c1c(N)n(nc1C(N)=O)c2c(Cl)cc(cc2Cl)C(F)(F)F InChI=1/C12H6Cl2F6N4O2S/c13-4-1-3(11(15,16)17)2-5(14)7(4)24-9(21)8(6(23-24)10(22)25)27(26)12(18,19)20/h1-2H,21H2,(H2,22,25)/t27? organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-Amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylsulfonyl-1H-pyrazole-3-carboxamide 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethanesulfinyl)-1H-pyrazole-3-carboxamide Not in list C12H6Cl2F6N4O2S FC(F)(F)S(=O)c1c(N)n(nc1C(N)=O)c2c(Cl)cc(cc2Cl)C(F)(F)F InChI=1/C12H6Cl2F6N4O2S/c13-4-1-3(11(15,16)17)2-5(14)7(4)24-9(21)8(6(23-24)10(22)25)27(26)12(18,19)20/h1-2H,21H2,(H2,22,25)/t27? organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-Amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylsulfonyl-1H-pyrazole-3-carboxamide 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethanesulfinyl)-1H-pyrazole-3-carboxamide Not in list C12H6Cl2F6N4O2S FC(F)(F)S(=O)c1c(N)n(nc1C(N)=O)c2c(Cl)cc(cc2Cl)C(F)(F)F InChI=1/C12H6Cl2F6N4O2S/c13-4-1-3(11(15,16)17)2-5(14)7(4)24-9(21)8(6(23-24)10(22)25)27(26)12(18,19)20/h1-2H,21H2,(H2,22,25)/t27? organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-Amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylsulfonyl-1H-pyrazole-3-carboxamide 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethanesulfinyl)-1H-pyrazole-3-carboxamide Not in list C12H6Cl2F6N4O2S FC(F)(F)S(=O)c1c(N)n(nc1C(N)=O)c2c(Cl)cc(cc2Cl)C(F)(F)F InChI=1/C12H6Cl2F6N4O2S/c13-4-1-3(11(15,16)17)2-5(14)7(4)24-9(21)8(6(23-24)10(22)25)27(26)12(18,19)20/h1-2H,21H2,(H2,22,25)/t27? organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-Amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylsulfonyl-1H-pyrazole-3-carboxamide 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethanesulfinyl)-1H-pyrazole-3-carboxamide Not in list C12H6Cl2F6N4O2S FC(F)(F)S(=O)c1c(N)n(nc1C(N)=O)c2c(Cl)cc(cc2Cl)C(F)(F)F InChI=1/C12H6Cl2F6N4O2S/c13-4-1-3(11(15,16)17)2-5(14)7(4)24-9(21)8(6(23-24)10(22)25)27(26)12(18,19)20/h1-2H,21H2,(H2,22,25)/t27? organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-Amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylsulfonyl-1H-pyrazole-3-carboxamide 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethanesulfinyl)-1H-pyrazole-3-carboxamide Not in list C12H6Cl2F6N4O2S FC(F)(F)S(=O)c1c(N)n(nc1C(N)=O)c2c(Cl)cc(cc2Cl)C(F)(F)F InChI=1/C12H6Cl2F6N4O2S/c13-4-1-3(11(15,16)17)2-5(14)7(4)24-9(21)8(6(23-24)10(22)25)27(26)12(18,19)20/h1-2H,21H2,(H2,22,25)/t27? organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-Amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylsulfonyl-1H-pyrazole-3-carboxamide 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethanesulfinyl)-1H-pyrazole-3-carboxamide Not in list C12H6Cl2F6N4O2S FC(F)(F)S(=O)c1c(N)n(nc1C(N)=O)c2c(Cl)cc(cc2Cl)C(F)(F)F InChI=1/C12H6Cl2F6N4O2S/c13-4-1-3(11(15,16)17)2-5(14)7(4)24-9(21)8(6(23-24)10(22)25)27(26)12(18,19)20/h1-2H,21H2,(H2,22,25)/t27? organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-Amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylsulfonyl-1H-pyrazole-3-carboxamide 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethanesulfinyl)-1H-pyrazole-3-carboxamide Not in list C12H6Cl2F6N4O2S FC(F)(F)S(=O)c1c(N)n(nc1C(N)=O)c2c(Cl)cc(cc2Cl)C(F)(F)F InChI=1/C12H6Cl2F6N4O2S/c13-4-1-3(11(15,16)17)2-5(14)7(4)24-9(21)8(6(23-24)10(22)25)27(26)12(18,19)20/h1-2H,21H2,(H2,22,25)/t27? organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes with Negative RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-Amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylsulfonyl-1H-pyrazole-3-carboxamide 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethanesulfinyl)-1H-pyrazole-3-carboxamide Not in list C12H6Cl2F6N4O2S FC(F)(F)S(=O)c1c(N)n(nc1C(N)=O)c2c(Cl)cc(cc2Cl)C(F)(F)F InChI=1/C12H6Cl2F6N4O2S/c13-4-1-3(11(15,16)17)2-5(14)7(4)24-9(21)8(6(23-24)10(22)25)27(26)12(18,19)20/h1-2H,21H2,(H2,22,25)/t27? organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes with Positive RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-Amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylsulfonyl-1H-pyrazole-3-carboxamide 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethanesulfinyl)-1H-pyrazole-3-carboxamide Not in list C12H6Cl2F6N4O2S FC(F)(F)S(=O)c1c(N)n(nc1C(N)=O)c2c(Cl)cc(cc2Cl)C(F)(F)F InChI=1/C12H6Cl2F6N4O2S/c13-4-1-3(11(15,16)17)2-5(14)7(4)24-9(21)8(6(23-24)10(22)25)27(26)12(18,19)20/h1-2H,21H2,(H2,22,25)/t27? organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable Rat (as animal) Sprague-Dawley 14 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Fipronil 120068-37-3 single chemical entity Component is a metabolite of the substance 5-Amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylsulfonyl-1H-pyrazole-3-carboxamide 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethanesulfinyl)-1H-pyrazole-3-carboxamide Not in list C12H6Cl2F6N4O2S FC(F)(F)S(=O)c1c(N)n(nc1C(N)=O)c2c(Cl)cc(cc2Cl)C(F)(F)F InChI=1/C12H6Cl2F6N4O2S/c13-4-1-3(11(15,16)17)2-5(14)7(4)24-9(21)8(6(23-24)10(22)25)27(26)12(18,19)20/h1-2H,21H2,(H2,22,25)/t27? organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable Rat (as animal) Sprague-Dawley 14 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: France Fipronil 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil. 27May2013 2013 doi:10.2903/j.efsa.2013.3158
+Hymexazol 233-000-6 10004-44-1 single chemical entity Component is identical to the substance Hymexazol 233-000-6 10004-44-1 5-methylisoxazol-3(2H)-one Hymexazol C4H5NO2 O=C1C=C(C)ON1 InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Finland Hymexazol (Revised/Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol 13Aug2010 2010 doi:10.2903/j.efsa.2010.1653
+Hymexazol 233-000-6 10004-44-1 single chemical entity Component is identical to the substance Hymexazol 233-000-6 10004-44-1 5-methylisoxazol-3(2H)-one Hymexazol C4H5NO2 O=C1C=C(C)ON1 InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Finland Hymexazol (Revised/Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol 13Aug2010 2010 doi:10.2903/j.efsa.2010.1653
+Hymexazol 233-000-6 10004-44-1 single chemical entity Component is identical to the substance Hymexazol 233-000-6 10004-44-1 5-methylisoxazol-3(2H)-one Hymexazol C4H5NO2 O=C1C=C(C)ON1 InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Finland Hymexazol (Revised/Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol 13Aug2010 2010 doi:10.2903/j.efsa.2010.1653
+Hymexazol 233-000-6 10004-44-1 single chemical entity Component is identical to the substance Hymexazol 233-000-6 10004-44-1 5-methylisoxazol-3(2H)-one Hymexazol C4H5NO2 O=C1C=C(C)ON1 InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Finland Hymexazol (Revised/Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol 13Aug2010 2010 doi:10.2903/j.efsa.2010.1653
+Hymexazol 233-000-6 10004-44-1 single chemical entity Component is identical to the substance Hymexazol 233-000-6 10004-44-1 5-methylisoxazol-3(2H)-one Hymexazol C4H5NO2 O=C1C=C(C)ON1 InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Finland Hymexazol (Revised/Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol 13Aug2010 2010 doi:10.2903/j.efsa.2010.1653
+Hymexazol 233-000-6 10004-44-1 single chemical entity Component is identical to the substance Hymexazol 233-000-6 10004-44-1 5-methylisoxazol-3(2H)-one Hymexazol C4H5NO2 O=C1C=C(C)ON1 InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Finland Hymexazol (Revised/Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol 13Aug2010 2010 doi:10.2903/j.efsa.2010.1653
+Hymexazol 233-000-6 10004-44-1 single chemical entity Component is identical to the substance Hymexazol 233-000-6 10004-44-1 5-methylisoxazol-3(2H)-one Hymexazol C4H5NO2 O=C1C=C(C)ON1 InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Finland Hymexazol (Revised/Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol 13Aug2010 2010 doi:10.2903/j.efsa.2010.1653
+Hymexazol 233-000-6 10004-44-1 single chemical entity Component is identical to the substance Hymexazol 233-000-6 10004-44-1 5-methylisoxazol-3(2H)-one Hymexazol C4H5NO2 O=C1C=C(C)ON1 InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Finland Hymexazol (Revised/Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol 13Aug2010 2010 doi:10.2903/j.efsa.2010.1653
+Hymexazol 233-000-6 10004-44-1 single chemical entity Component is identical to the substance Hymexazol 233-000-6 10004-44-1 5-methylisoxazol-3(2H)-one Hymexazol C4H5NO2 O=C1C=C(C)ON1 InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Finland Hymexazol (Revised/Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol 13Aug2010 2010 doi:10.2903/j.efsa.2010.1653
+Hymexazol 233-000-6 10004-44-1 single chemical entity Component is identical to the substance Hymexazol 233-000-6 10004-44-1 5-methylisoxazol-3(2H)-one Hymexazol C4H5NO2 O=C1C=C(C)ON1 InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Finland Hymexazol (Revised/Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol 13Aug2010 2010 doi:10.2903/j.efsa.2010.1653
+Hymexazol 233-000-6 10004-44-1 single chemical entity Component is identical to the substance Hymexazol 233-000-6 10004-44-1 5-methylisoxazol-3(2H)-one Hymexazol C4H5NO2 O=C1C=C(C)ON1 InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Finland Hymexazol (Revised/Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol 13Aug2010 2010 doi:10.2903/j.efsa.2010.1653
+Hymexazol 233-000-6 10004-44-1 single chemical entity Component is identical to the substance Hymexazol 233-000-6 10004-44-1 5-methylisoxazol-3(2H)-one Hymexazol C4H5NO2 O=C1C=C(C)ON1 InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Finland Hymexazol (Revised/Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol 13Aug2010 2010 doi:10.2903/j.efsa.2010.1653
+Hymexazol 233-000-6 10004-44-1 single chemical entity Component is identical to the substance Hymexazol 233-000-6 10004-44-1 5-methylisoxazol-3(2H)-one Hymexazol C4H5NO2 O=C1C=C(C)ON1 InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Finland Hymexazol (Revised/Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol 13Aug2010 2010 doi:10.2903/j.efsa.2010.1653
+Hymexazol 233-000-6 10004-44-1 single chemical entity Component is identical to the substance Hymexazol 233-000-6 10004-44-1 5-methylisoxazol-3(2H)-one Hymexazol C4H5NO2 O=C1C=C(C)ON1 InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Finland Hymexazol (Revised/Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol 13Aug2010 2010 doi:10.2903/j.efsa.2010.1653
+Hymexazol 233-000-6 10004-44-1 single chemical entity Component is identical to the substance Hymexazol 233-000-6 10004-44-1 5-methylisoxazol-3(2H)-one Hymexazol C4H5NO2 O=C1C=C(C)ON1 InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Finland Hymexazol (Revised/Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol 13Aug2010 2010 doi:10.2903/j.efsa.2010.1653
+Hymexazol 233-000-6 10004-44-1 single chemical entity Component is identical to the substance Hymexazol 233-000-6 10004-44-1 5-methylisoxazol-3(2H)-one Hymexazol C4H5NO2 O=C1C=C(C)ON1 InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Finland Hymexazol (Revised/Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol 13Aug2010 2010 doi:10.2903/j.efsa.2010.1653
+Hymexazol 233-000-6 10004-44-1 single chemical entity Component is identical to the substance Hymexazol 233-000-6 10004-44-1 5-methylisoxazol-3(2H)-one Hymexazol C4H5NO2 O=C1C=C(C)ON1 InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Finland Hymexazol (Revised/Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol 13Aug2010 2010 doi:10.2903/j.efsa.2010.1653
+Hymexazol 233-000-6 10004-44-1 single chemical entity Component is identical to the substance Hymexazol 233-000-6 10004-44-1 5-methylisoxazol-3(2H)-one Hymexazol C4H5NO2 O=C1C=C(C)ON1 InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Finland Hymexazol (Revised/Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol 13Aug2010 2010 doi:10.2903/j.efsa.2010.1653
+Hymexazol 233-000-6 10004-44-1 single chemical entity Component is identical to the substance Hymexazol 233-000-6 10004-44-1 5-methylisoxazol-3(2H)-one Hymexazol C4H5NO2 O=C1C=C(C)ON1 InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Finland Hymexazol (Revised/Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol 13Aug2010 2010 doi:10.2903/j.efsa.2010.1653
+Hymexazol 233-000-6 10004-44-1 single chemical entity Component is identical to the substance Hymexazol 233-000-6 10004-44-1 5-methylisoxazol-3(2H)-one Hymexazol C4H5NO2 O=C1C=C(C)ON1 InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Finland Hymexazol (Revised/Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol 13Aug2010 2010 doi:10.2903/j.efsa.2010.1653
+Hymexazol 233-000-6 10004-44-1 single chemical entity Component is identical to the substance Hymexazol 233-000-6 10004-44-1 5-methylisoxazol-3(2H)-one Hymexazol C4H5NO2 O=C1C=C(C)ON1 InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Finland Hymexazol (Revised/Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol 13Aug2010 2010 doi:10.2903/j.efsa.2010.1653
+Hymexazol 233-000-6 10004-44-1 single chemical entity Component is identical to the substance Hymexazol 233-000-6 10004-44-1 5-methylisoxazol-3(2H)-one Hymexazol C4H5NO2 O=C1C=C(C)ON1 InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Finland Hymexazol (Revised/Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol 13Aug2010 2010 doi:10.2903/j.efsa.2010.1653
+Hymexazol 233-000-6 10004-44-1 single chemical entity Component is identical to the substance Hymexazol 233-000-6 10004-44-1 5-methylisoxazol-3(2H)-one Hymexazol C4H5NO2 O=C1C=C(C)ON1 InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Negative no information RMS: Finland Hymexazol (Revised/Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol 13Aug2010 2010 doi:10.2903/j.efsa.2010.1653
+Hymexazol 233-000-6 10004-44-1 single chemical entity Component is identical to the substance Hymexazol 233-000-6 10004-44-1 5-methylisoxazol-3(2H)-one Hymexazol C4H5NO2 O=C1C=C(C)ON1 InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative no information RMS: Finland Hymexazol (Revised/Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol 13Aug2010 2010 doi:10.2903/j.efsa.2010.1653
+Hymexazol 233-000-6 10004-44-1 single chemical entity Component is identical to the substance Hymexazol 233-000-6 10004-44-1 5-methylisoxazol-3(2H)-one Hymexazol C4H5NO2 O=C1C=C(C)ON1 InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle without Positive RMS: Finland Hymexazol (Revised/Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol 13Aug2010 2010 doi:10.2903/j.efsa.2010.1653
+Hymexazol 233-000-6 10004-44-1 single chemical entity Component is identical to the substance Hymexazol 233-000-6 10004-44-1 5-methylisoxazol-3(2H)-one Hymexazol C4H5NO2 O=C1C=C(C)ON1 InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes, concurrent vehicle with Positive RMS: Finland Hymexazol (Revised/Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol 13Aug2010 2010 doi:10.2903/j.efsa.2010.1653
+Hymexazol 233-000-6 10004-44-1 single chemical entity Component is identical to the substance Hymexazol 233-000-6 10004-44-1 5-methylisoxazol-3(2H)-one Hymexazol C4H5NO2 O=C1C=C(C)ON1 InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6) organic compound Other Other genome mutation Drosophila SLRL test in vivo According to OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster) No Acceptable Drosophila melanogaster (as animal) Oregon-R 75 Male oral: feed 3.0000000000 D yes not applicable Negative RMS: Finland Hymexazol (Revised/Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol 13Aug2010 2010 doi:10.2903/j.efsa.2010.1653
+Hymexazol 233-000-6 10004-44-1 single chemical entity Component is identical to the substance Hymexazol 233-000-6 10004-44-1 5-methylisoxazol-3(2H)-one Hymexazol C4H5NO2 O=C1C=C(C)ON1 InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Negative RMS: Finland Hymexazol (Revised/Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol 13Aug2010 2010 doi:10.2903/j.efsa.2010.1653
+Hymexazol 233-000-6 10004-44-1 single chemical entity Component is identical to the substance Hymexazol 233-000-6 10004-44-1 5-methylisoxazol-3(2H)-one Hymexazol C4H5NO2 O=C1C=C(C)ON1 InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: Finland Hymexazol (Revised/Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol 13Aug2010 2010 doi:10.2903/j.efsa.2010.1653
+Hymexazol 233-000-6 10004-44-1 single chemical entity Component is identical to the substance Hymexazol 233-000-6 10004-44-1 5-methylisoxazol-3(2H)-one Hymexazol C4H5NO2 O=C1C=C(C)ON1 InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) ICR 5 Male oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Finland Hymexazol (Revised/Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol 13Aug2010 2010 doi:10.2903/j.efsa.2010.1653
+Hymexazol 233-000-6 10004-44-1 single chemical entity Component is identical to the substance Hymexazol 233-000-6 10004-44-1 5-methylisoxazol-3(2H)-one Hymexazol C4H5NO2 O=C1C=C(C)ON1 InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) ICR 5 Male oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Finland Hymexazol (Revised/Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol 13Aug2010 2010 doi:10.2903/j.efsa.2010.1653
+Hymexazol 233-000-6 10004-44-1 single chemical entity Component is identical to the substance Hymexazol 233-000-6 10004-44-1 5-methylisoxazol-3(2H)-one Hymexazol C4H5NO2 O=C1C=C(C)ON1 InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6) organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Rat (as animal) Not reported No data oral: unspecified 24.0000000000 h yes not applicable Positive RMS: Finland Hymexazol (Revised/Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol 13Aug2010 2010 doi:10.2903/j.efsa.2010.1653
+Hymexazol 233-000-6 10004-44-1 single chemical entity Component is identical to the substance Hymexazol 233-000-6 10004-44-1 5-methylisoxazol-3(2H)-one Hymexazol C4H5NO2 O=C1C=C(C)ON1 InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6) organic compound Other Other chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Rat (as animal) Not reported No data oral: unspecified 48.0000000000 h yes not applicable Positive RMS: Finland Hymexazol (Revised/Additional Report) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol 13Aug2010 2010 doi:10.2903/j.efsa.2010.1653
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is identical to the substance Triadimenol 259-537-6 55219-65-3 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Triadimenol C14H18ClN3O2 OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1 InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is identical to the substance Triadimenol 259-537-6 55219-65-3 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Triadimenol C14H18ClN3O2 OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1 InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is identical to the substance Triadimenol 259-537-6 55219-65-3 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Triadimenol C14H18ClN3O2 OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1 InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is identical to the substance Triadimenol 259-537-6 55219-65-3 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Triadimenol C14H18ClN3O2 OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1 InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3 organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes, concurrent vehicle no data Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is identical to the substance Triadimenol 259-537-6 55219-65-3 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Triadimenol C14H18ClN3O2 OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1 InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is identical to the substance Triadimenol 259-537-6 55219-65-3 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Triadimenol C14H18ClN3O2 OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1 InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is identical to the substance Triadimenol 259-537-6 55219-65-3 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Triadimenol C14H18ClN3O2 OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1 InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is identical to the substance Triadimenol 259-537-6 55219-65-3 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Triadimenol C14H18ClN3O2 OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1 InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is identical to the substance Triadimenol 259-537-6 55219-65-3 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Triadimenol C14H18ClN3O2 OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1 InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is identical to the substance Triadimenol 259-537-6 55219-65-3 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Triadimenol C14H18ClN3O2 OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1 InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is identical to the substance Triadimenol 259-537-6 55219-65-3 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Triadimenol C14H18ClN3O2 OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1 InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is identical to the substance Triadimenol 259-537-6 55219-65-3 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Triadimenol C14H18ClN3O2 OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1 InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is identical to the substance Triadimenol 259-537-6 55219-65-3 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Triadimenol C14H18ClN3O2 OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1 InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3 organic compound Other Other DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes, concurrent vehicle no data Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is identical to the substance Triadimenol 259-537-6 55219-65-3 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Triadimenol C14H18ClN3O2 OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1 InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is identical to the substance Triadimenol 259-537-6 55219-65-3 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Triadimenol C14H18ClN3O2 OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1 InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is identical to the substance Triadimenol 259-537-6 55219-65-3 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Triadimenol C14H18ClN3O2 OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1 InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is identical to the substance Triadimenol 259-537-6 55219-65-3 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Triadimenol C14H18ClN3O2 OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1 InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is identical to the substance Triadimenol 259-537-6 55219-65-3 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Triadimenol C14H18ClN3O2 OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1 InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is identical to the substance Triadimenol 259-537-6 55219-65-3 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Triadimenol C14H18ClN3O2 OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1 InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3 organic compound Other Other gene mutation Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M17 Not reported yes, concurrent vehicle no data Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is identical to the substance Triadimenol 259-537-6 55219-65-3 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Triadimenol C14H18ClN3O2 OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1 InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is identical to the substance Triadimenol 259-537-6 55219-65-3 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Triadimenol C14H18ClN3O2 OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1 InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is identical to the substance Triadimenol 259-537-6 55219-65-3 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Triadimenol C14H18ClN3O2 OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1 InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is identical to the substance Triadimenol 259-537-6 55219-65-3 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Triadimenol C14H18ClN3O2 OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1 InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) Not reported Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is identical to the substance Triadimenol 259-537-6 55219-65-3 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Triadimenol C14H18ClN3O2 OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1 InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is identical to the substance Triadimenol 259-537-6 55219-65-3 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Triadimenol C14H18ClN3O2 OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1 InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is identical to the substance Triadimenol 259-537-6 55219-65-3 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Triadimenol C14H18ClN3O2 OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1 InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3 organic compound Other Other gene mutation Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes, concurrent vehicle no data Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is identical to the substance Triadimenol 259-537-6 55219-65-3 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Triadimenol C14H18ClN3O2 OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1 InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Escherichia coli (as organism) Not reported Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is identical to the substance Triadimenol 259-537-6 55219-65-3 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Triadimenol C14H18ClN3O2 OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1 InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is identical to the substance Triadimenol 259-537-6 55219-65-3 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Triadimenol C14H18ClN3O2 OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1 InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative no information RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is identical to the substance Triadimenol 259-537-6 55219-65-3 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Triadimenol C14H18ClN3O2 OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1 InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Negative no information RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is identical to the substance Triadimenol 259-537-6 55219-65-3 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Triadimenol C14H18ClN3O2 OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1 InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3 organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro Equivalent or similar to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) Yes Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is identical to the substance Triadimenol 259-537-6 55219-65-3 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Triadimenol C14H18ClN3O2 OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1 InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3 organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro According to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is identical to the substance Triadimenol 259-537-6 55219-65-3 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Triadimenol C14H18ClN3O2 OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1 InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3 organic compound Other Other chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) Yes Acceptable House mouse (as animal) NMRI 50 Male oral: gavage 48.0000000000 D no data not applicable Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance 1,2,4-Triazole 206-022-9 288-88-0 1H-1,2,4-triazole Triazole, 1,2,4- C2H3N3 C1=NC=NN1 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Rat (as animal) hepatocytes Not reported yes without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole acetic acid 28711-29-7 2-(1,2,4-Triazol-1-yl)acetic acid Triazole acetic acid C4H5N3O2 C1=NN(C=N1)CC(=O)O InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable Hamster (as animal) Chinese 16 Male/Female oral: gavage 24.0000000000 h yes not applicable Negative no evidence RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable Hamster (as animal) Chinese 16 Male/Female oral: gavage 48.0000000000 h yes not applicable Negative no evidence RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable Hamster (as animal) Chinese 16 Male/Female oral: gavage 16.0000000000 h yes not applicable Negative no evidence RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CBA 5 Male intraperitoneal 48.0000000000 h yes not applicable Negative no evidence RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CBA 5 Male intraperitoneal 72.0000000000 h yes not applicable Negative no evidence RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CBA 5 Male intraperitoneal 24.0000000000 h yes not applicable Negative no evidence RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 72.0000000000 h yes not applicable Negative no evidence RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 48.0000000000 h yes not applicable Negative no evidence RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Triadimenol 259-537-6 55219-65-3 single chemical entity Component is a metabolite of the substance Triazole alanine 233-301-2 10109-05-4 2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid Triazole alanine C5H8N4O2 C1=NNC(=N1)CC(C(=O)O)N InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) NMRI 10 Male/Female oral: gavage 24.0000000000 h yes not applicable Ambiguous no evidence RMS: The United Kingdom Triadimenol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol 17Oct2008 2008 doi:10.2903/j.efsa.2008.177r
+Flutriafol 616-367-0 76674-21-0 single chemical entity Component is identical to the substance Flutriafol 616-367-0 76674-21-0 1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol Flutriafol C16H13F2N3O OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Flutriafol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol 21Oct2010 2010 doi:10.2903/j.efsa.2010.1868
+Flutriafol 616-367-0 76674-21-0 single chemical entity Component is identical to the substance Flutriafol 616-367-0 76674-21-0 1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol Flutriafol C16H13F2N3O OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Flutriafol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol 21Oct2010 2010 doi:10.2903/j.efsa.2010.1868
+Flutriafol 616-367-0 76674-21-0 single chemical entity Component is identical to the substance Flutriafol 616-367-0 76674-21-0 1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol Flutriafol C16H13F2N3O OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Flutriafol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol 21Oct2010 2010 doi:10.2903/j.efsa.2010.1868
+Flutriafol 616-367-0 76674-21-0 single chemical entity Component is identical to the substance Flutriafol 616-367-0 76674-21-0 1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol Flutriafol C16H13F2N3O OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Flutriafol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol 21Oct2010 2010 doi:10.2903/j.efsa.2010.1868
+Flutriafol 616-367-0 76674-21-0 single chemical entity Component is identical to the substance Flutriafol 616-367-0 76674-21-0 1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol Flutriafol C16H13F2N3O OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Flutriafol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol 21Oct2010 2010 doi:10.2903/j.efsa.2010.1868
+Flutriafol 616-367-0 76674-21-0 single chemical entity Component is identical to the substance Flutriafol 616-367-0 76674-21-0 1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol Flutriafol C16H13F2N3O OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Flutriafol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol 21Oct2010 2010 doi:10.2903/j.efsa.2010.1868
+Flutriafol 616-367-0 76674-21-0 single chemical entity Component is identical to the substance Flutriafol 616-367-0 76674-21-0 1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol Flutriafol C16H13F2N3O OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Flutriafol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol 21Oct2010 2010 doi:10.2903/j.efsa.2010.1868
+Flutriafol 616-367-0 76674-21-0 single chemical entity Component is identical to the substance Flutriafol 616-367-0 76674-21-0 1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol Flutriafol C16H13F2N3O OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Flutriafol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol 21Oct2010 2010 doi:10.2903/j.efsa.2010.1868
+Flutriafol 616-367-0 76674-21-0 single chemical entity Component is identical to the substance Flutriafol 616-367-0 76674-21-0 1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol Flutriafol C16H13F2N3O OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Flutriafol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol 21Oct2010 2010 doi:10.2903/j.efsa.2010.1868
+Flutriafol 616-367-0 76674-21-0 single chemical entity Component is identical to the substance Flutriafol 616-367-0 76674-21-0 1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol Flutriafol C16H13F2N3O OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Flutriafol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol 21Oct2010 2010 doi:10.2903/j.efsa.2010.1868
+Flutriafol 616-367-0 76674-21-0 single chemical entity Component is identical to the substance Flutriafol 616-367-0 76674-21-0 1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol Flutriafol C16H13F2N3O OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative no information RMS: The United Kingdom Flutriafol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol 21Oct2010 2010 doi:10.2903/j.efsa.2010.1868
+Flutriafol 616-367-0 76674-21-0 single chemical entity Component is identical to the substance Flutriafol 616-367-0 76674-21-0 1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol Flutriafol C16H13F2N3O OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Positive no information RMS: The United Kingdom Flutriafol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol 21Oct2010 2010 doi:10.2903/j.efsa.2010.1868
+Flutriafol 616-367-0 76674-21-0 single chemical entity Component is identical to the substance Flutriafol 616-367-0 76674-21-0 1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol Flutriafol C16H13F2N3O OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported no data with Negative RMS: The United Kingdom Flutriafol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol 21Oct2010 2010 doi:10.2903/j.efsa.2010.1868
+Flutriafol 616-367-0 76674-21-0 single chemical entity Component is identical to the substance Flutriafol 616-367-0 76674-21-0 1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol Flutriafol C16H13F2N3O OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported no data without Negative RMS: The United Kingdom Flutriafol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol 21Oct2010 2010 doi:10.2903/j.efsa.2010.1868
+Flutriafol 616-367-0 76674-21-0 single chemical entity Component is identical to the substance Flutriafol 616-367-0 76674-21-0 1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol Flutriafol C16H13F2N3O OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Alderly Park Rat 5 Male oral: gavage 24.0000000000 h yes not applicable Negative RMS: The United Kingdom Flutriafol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol 21Oct2010 2010 doi:10.2903/j.efsa.2010.1868
+Flutriafol 616-367-0 76674-21-0 single chemical entity Component is identical to the substance Flutriafol 616-367-0 76674-21-0 1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol Flutriafol C16H13F2N3O OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2 organic compound Other Other chromosome aberration chromosome aberration assay in vivo Equivalent or similar to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) Yes Acceptable Rat (as animal) Alderly Park Rat 5 Male oral: gavage 6.0000000000 h yes not applicable Negative RMS: The United Kingdom Flutriafol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol 21Oct2010 2010 doi:10.2903/j.efsa.2010.1868
+Flutriafol 616-367-0 76674-21-0 single chemical entity Component is identical to the substance Flutriafol 616-367-0 76674-21-0 1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol Flutriafol C16H13F2N3O OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) C57BL 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The United Kingdom Flutriafol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol 21Oct2010 2010 doi:10.2903/j.efsa.2010.1868
+Flutriafol 616-367-0 76674-21-0 single chemical entity Component is identical to the substance Flutriafol 616-367-0 76674-21-0 1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol Flutriafol C16H13F2N3O OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) C57BL 10 Male/Female oral: gavage 72.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The United Kingdom Flutriafol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol 21Oct2010 2010 doi:10.2903/j.efsa.2010.1868
+Flutriafol 616-367-0 76674-21-0 single chemical entity Component is identical to the substance Flutriafol 616-367-0 76674-21-0 1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol Flutriafol C16H13F2N3O OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) C57BL 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: The United Kingdom Flutriafol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol 21Oct2010 2010 doi:10.2903/j.efsa.2010.1868
+Flutriafol 616-367-0 76674-21-0 single chemical entity Component is identical to the substance Flutriafol 616-367-0 76674-21-0 1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol Flutriafol C16H13F2N3O OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2 organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Sprague-Dawley 5 Male oral: gavage 12.0000000000 h yes not applicable Negative RMS: The United Kingdom Flutriafol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol 21Oct2010 2010 doi:10.2903/j.efsa.2010.1868
+Flutriafol 616-367-0 76674-21-0 single chemical entity Component is identical to the substance Flutriafol 616-367-0 76674-21-0 1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol Flutriafol C16H13F2N3O OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2 organic compound Other Other DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Sprague-Dawley 5 Male oral: gavage 4.0000000000 h yes not applicable Negative RMS: The United Kingdom Flutriafol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol 21Oct2010 2010 doi:10.2903/j.efsa.2010.1868
+Flutriafol 616-367-0 76674-21-0 single chemical entity Component is identical to the substance Flutriafol 616-367-0 76674-21-0 1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol Flutriafol C16H13F2N3O OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2 organic compound Other Other chromosome aberration dominant lethal assay in vivo Equivalent or similar to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) Yes Acceptable House mouse (as animal) CD-1 15 Male oral: gavage 7.0000000000 D no data not applicable Negative RMS: The United Kingdom Flutriafol 2006 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol 21Oct2010 2010 doi:10.2903/j.efsa.2010.1868
+Flutriafol 616-367-0 76674-21-0 single chemical entity Component is identical to the substance Flutriafol 616-367-0 76674-21-0 1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol Flutriafol C16H13F2N3O OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Flutriafol (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol 21Oct2010 2010 doi:10.2903/j.efsa.2010.1868
+Flutriafol 616-367-0 76674-21-0 single chemical entity Component is identical to the substance Flutriafol 616-367-0 76674-21-0 1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol Flutriafol C16H13F2N3O OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Flutriafol (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol 21Oct2010 2010 doi:10.2903/j.efsa.2010.1868
+Flutriafol 616-367-0 76674-21-0 single chemical entity Component is identical to the substance Flutriafol 616-367-0 76674-21-0 1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol Flutriafol C16H13F2N3O OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Flutriafol (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol 21Oct2010 2010 doi:10.2903/j.efsa.2010.1868
+Flutriafol 616-367-0 76674-21-0 single chemical entity Component is identical to the substance Flutriafol 616-367-0 76674-21-0 1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol Flutriafol C16H13F2N3O OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Flutriafol (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol 21Oct2010 2010 doi:10.2903/j.efsa.2010.1868
+Flutriafol 616-367-0 76674-21-0 single chemical entity Component is identical to the substance Flutriafol 616-367-0 76674-21-0 1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol Flutriafol C16H13F2N3O OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Flutriafol (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol 21Oct2010 2010 doi:10.2903/j.efsa.2010.1868
+Flutriafol 616-367-0 76674-21-0 single chemical entity Component is identical to the substance Flutriafol 616-367-0 76674-21-0 1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol Flutriafol C16H13F2N3O OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Flutriafol (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol 21Oct2010 2010 doi:10.2903/j.efsa.2010.1868
+Flutriafol 616-367-0 76674-21-0 single chemical entity Component is identical to the substance Flutriafol 616-367-0 76674-21-0 1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol Flutriafol C16H13F2N3O OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Flutriafol (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol 21Oct2010 2010 doi:10.2903/j.efsa.2010.1868
+Flutriafol 616-367-0 76674-21-0 single chemical entity Component is identical to the substance Flutriafol 616-367-0 76674-21-0 1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol Flutriafol C16H13F2N3O OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Flutriafol (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol 21Oct2010 2010 doi:10.2903/j.efsa.2010.1868
+Flutriafol 616-367-0 76674-21-0 single chemical entity Component is identical to the substance Flutriafol 616-367-0 76674-21-0 1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol Flutriafol C16H13F2N3O OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Flutriafol (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol 21Oct2010 2010 doi:10.2903/j.efsa.2010.1868
+Flutriafol 616-367-0 76674-21-0 single chemical entity Component is identical to the substance Flutriafol 616-367-0 76674-21-0 1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol Flutriafol C16H13F2N3O OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Flutriafol (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol 21Oct2010 2010 doi:10.2903/j.efsa.2010.1868
+Flutriafol 616-367-0 76674-21-0 single chemical entity Component is identical to the substance Flutriafol 616-367-0 76674-21-0 1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol Flutriafol C16H13F2N3O OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Negative small colonies RMS: The United Kingdom Flutriafol (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol 21Oct2010 2010 doi:10.2903/j.efsa.2010.1868
+Flutriafol 616-367-0 76674-21-0 single chemical entity Component is identical to the substance Flutriafol 616-367-0 76674-21-0 1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol Flutriafol C16H13F2N3O OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative large colonies RMS: The United Kingdom Flutriafol (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol 21Oct2010 2010 doi:10.2903/j.efsa.2010.1868
+Flutriafol 616-367-0 76674-21-0 single chemical entity Component is identical to the substance Flutriafol 616-367-0 76674-21-0 1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol Flutriafol C16H13F2N3O OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative small colonies RMS: The United Kingdom Flutriafol (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol 21Oct2010 2010 doi:10.2903/j.efsa.2010.1868
+Flutriafol 616-367-0 76674-21-0 single chemical entity Component is identical to the substance Flutriafol 616-367-0 76674-21-0 1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol Flutriafol C16H13F2N3O OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Negative large colonies RMS: The United Kingdom Flutriafol (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol 21Oct2010 2010 doi:10.2903/j.efsa.2010.1868
+Flutriafol 616-367-0 76674-21-0 single chemical entity Component is identical to the substance Flutriafol 616-367-0 76674-21-0 1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol Flutriafol C16H13F2N3O OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes without Negative RMS: The United Kingdom Flutriafol (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol 21Oct2010 2010 doi:10.2903/j.efsa.2010.1868
+Flutriafol 616-367-0 76674-21-0 single chemical entity Component is identical to the substance Flutriafol 616-367-0 76674-21-0 1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol Flutriafol C16H13F2N3O OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes with Negative RMS: The United Kingdom Flutriafol (Additional report) 2010 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol 21Oct2010 2010 doi:10.2903/j.efsa.2010.1868
+Fenpyrazamine 473798-59-3 single chemical entity Component is identical to the substance Fenpyrazamine 473798-59-3 S-allyl 5-amino-2,3-dihydro-2-isopropyl-3-oxo-4-(o-tolyl)pyrazole-1-carbothioate Fenpyrazamine C17H21N3O2S n1(c(c(c(=O)n1C(C)C)c1ccccc1C)N)C(=O)SCC=C InChI=1S/C17H21N3O2S/c1-5-10-23-17(22)20-15(18)14(16(21)19(20)11(2)3)13-9-7-6-8-12(13)4/h5-9,11H,1,10,18H2,2-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Austria Fenpyrazamine (S-2188) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyrazamine 27Jan2012 2012 doi:10.2903/j.efsa.2012.2496
+Fenpyrazamine 473798-59-3 single chemical entity Component is identical to the substance Fenpyrazamine 473798-59-3 S-allyl 5-amino-2,3-dihydro-2-isopropyl-3-oxo-4-(o-tolyl)pyrazole-1-carbothioate Fenpyrazamine C17H21N3O2S n1(c(c(c(=O)n1C(C)C)c1ccccc1C)N)C(=O)SCC=C InChI=1S/C17H21N3O2S/c1-5-10-23-17(22)20-15(18)14(16(21)19(20)11(2)3)13-9-7-6-8-12(13)4/h5-9,11H,1,10,18H2,2-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Austria Fenpyrazamine (S-2188) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyrazamine 27Jan2012 2012 doi:10.2903/j.efsa.2012.2496
+Fenpyrazamine 473798-59-3 single chemical entity Component is identical to the substance Fenpyrazamine 473798-59-3 S-allyl 5-amino-2,3-dihydro-2-isopropyl-3-oxo-4-(o-tolyl)pyrazole-1-carbothioate Fenpyrazamine C17H21N3O2S n1(c(c(c(=O)n1C(C)C)c1ccccc1C)N)C(=O)SCC=C InChI=1S/C17H21N3O2S/c1-5-10-23-17(22)20-15(18)14(16(21)19(20)11(2)3)13-9-7-6-8-12(13)4/h5-9,11H,1,10,18H2,2-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Austria Fenpyrazamine (S-2188) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyrazamine 27Jan2012 2012 doi:10.2903/j.efsa.2012.2496
+Fenpyrazamine 473798-59-3 single chemical entity Component is identical to the substance Fenpyrazamine 473798-59-3 S-allyl 5-amino-2,3-dihydro-2-isopropyl-3-oxo-4-(o-tolyl)pyrazole-1-carbothioate Fenpyrazamine C17H21N3O2S n1(c(c(c(=O)n1C(C)C)c1ccccc1C)N)C(=O)SCC=C InChI=1S/C17H21N3O2S/c1-5-10-23-17(22)20-15(18)14(16(21)19(20)11(2)3)13-9-7-6-8-12(13)4/h5-9,11H,1,10,18H2,2-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Austria Fenpyrazamine (S-2188) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyrazamine 27Jan2012 2012 doi:10.2903/j.efsa.2012.2496
+Fenpyrazamine 473798-59-3 single chemical entity Component is identical to the substance Fenpyrazamine 473798-59-3 S-allyl 5-amino-2,3-dihydro-2-isopropyl-3-oxo-4-(o-tolyl)pyrazole-1-carbothioate Fenpyrazamine C17H21N3O2S n1(c(c(c(=O)n1C(C)C)c1ccccc1C)N)C(=O)SCC=C InChI=1S/C17H21N3O2S/c1-5-10-23-17(22)20-15(18)14(16(21)19(20)11(2)3)13-9-7-6-8-12(13)4/h5-9,11H,1,10,18H2,2-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Austria Fenpyrazamine (S-2188) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyrazamine 27Jan2012 2012 doi:10.2903/j.efsa.2012.2496
+Fenpyrazamine 473798-59-3 single chemical entity Component is identical to the substance Fenpyrazamine 473798-59-3 S-allyl 5-amino-2,3-dihydro-2-isopropyl-3-oxo-4-(o-tolyl)pyrazole-1-carbothioate Fenpyrazamine C17H21N3O2S n1(c(c(c(=O)n1C(C)C)c1ccccc1C)N)C(=O)SCC=C InChI=1S/C17H21N3O2S/c1-5-10-23-17(22)20-15(18)14(16(21)19(20)11(2)3)13-9-7-6-8-12(13)4/h5-9,11H,1,10,18H2,2-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Austria Fenpyrazamine (S-2188) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyrazamine 27Jan2012 2012 doi:10.2903/j.efsa.2012.2496
+Fenpyrazamine 473798-59-3 single chemical entity Component is identical to the substance Fenpyrazamine 473798-59-3 S-allyl 5-amino-2,3-dihydro-2-isopropyl-3-oxo-4-(o-tolyl)pyrazole-1-carbothioate Fenpyrazamine C17H21N3O2S n1(c(c(c(=O)n1C(C)C)c1ccccc1C)N)C(=O)SCC=C InChI=1S/C17H21N3O2S/c1-5-10-23-17(22)20-15(18)14(16(21)19(20)11(2)3)13-9-7-6-8-12(13)4/h5-9,11H,1,10,18H2,2-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Austria Fenpyrazamine (S-2188) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyrazamine 27Jan2012 2012 doi:10.2903/j.efsa.2012.2496
+Fenpyrazamine 473798-59-3 single chemical entity Component is identical to the substance Fenpyrazamine 473798-59-3 S-allyl 5-amino-2,3-dihydro-2-isopropyl-3-oxo-4-(o-tolyl)pyrazole-1-carbothioate Fenpyrazamine C17H21N3O2S n1(c(c(c(=O)n1C(C)C)c1ccccc1C)N)C(=O)SCC=C InChI=1S/C17H21N3O2S/c1-5-10-23-17(22)20-15(18)14(16(21)19(20)11(2)3)13-9-7-6-8-12(13)4/h5-9,11H,1,10,18H2,2-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Austria Fenpyrazamine (S-2188) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyrazamine 27Jan2012 2012 doi:10.2903/j.efsa.2012.2496
+Fenpyrazamine 473798-59-3 single chemical entity Component is identical to the substance Fenpyrazamine 473798-59-3 S-allyl 5-amino-2,3-dihydro-2-isopropyl-3-oxo-4-(o-tolyl)pyrazole-1-carbothioate Fenpyrazamine C17H21N3O2S n1(c(c(c(=O)n1C(C)C)c1ccccc1C)N)C(=O)SCC=C InChI=1S/C17H21N3O2S/c1-5-10-23-17(22)20-15(18)14(16(21)19(20)11(2)3)13-9-7-6-8-12(13)4/h5-9,11H,1,10,18H2,2-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Austria Fenpyrazamine (S-2188) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyrazamine 27Jan2012 2012 doi:10.2903/j.efsa.2012.2496
+Fenpyrazamine 473798-59-3 single chemical entity Component is identical to the substance Fenpyrazamine 473798-59-3 S-allyl 5-amino-2,3-dihydro-2-isopropyl-3-oxo-4-(o-tolyl)pyrazole-1-carbothioate Fenpyrazamine C17H21N3O2S n1(c(c(c(=O)n1C(C)C)c1ccccc1C)N)C(=O)SCC=C InChI=1S/C17H21N3O2S/c1-5-10-23-17(22)20-15(18)14(16(21)19(20)11(2)3)13-9-7-6-8-12(13)4/h5-9,11H,1,10,18H2,2-4H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Austria Fenpyrazamine (S-2188) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyrazamine 27Jan2012 2012 doi:10.2903/j.efsa.2012.2496
+Fenpyrazamine 473798-59-3 single chemical entity Component is identical to the substance Fenpyrazamine 473798-59-3 S-allyl 5-amino-2,3-dihydro-2-isopropyl-3-oxo-4-(o-tolyl)pyrazole-1-carbothioate Fenpyrazamine C17H21N3O2S n1(c(c(c(=O)n1C(C)C)c1ccccc1C)N)C(=O)SCC=C InChI=1S/C17H21N3O2S/c1-5-10-23-17(22)20-15(18)14(16(21)19(20)11(2)3)13-9-7-6-8-12(13)4/h5-9,11H,1,10,18H2,2-4H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Negative RMS: Austria Fenpyrazamine (S-2188) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyrazamine 27Jan2012 2012 doi:10.2903/j.efsa.2012.2496
+Fenpyrazamine 473798-59-3 single chemical entity Component is identical to the substance Fenpyrazamine 473798-59-3 S-allyl 5-amino-2,3-dihydro-2-isopropyl-3-oxo-4-(o-tolyl)pyrazole-1-carbothioate Fenpyrazamine C17H21N3O2S n1(c(c(c(=O)n1C(C)C)c1ccccc1C)N)C(=O)SCC=C InChI=1S/C17H21N3O2S/c1-5-10-23-17(22)20-15(18)14(16(21)19(20)11(2)3)13-9-7-6-8-12(13)4/h5-9,11H,1,10,18H2,2-4H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: Austria Fenpyrazamine (S-2188) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyrazamine 27Jan2012 2012 doi:10.2903/j.efsa.2012.2496
+Fenpyrazamine 473798-59-3 single chemical entity Component is identical to the substance Fenpyrazamine 473798-59-3 S-allyl 5-amino-2,3-dihydro-2-isopropyl-3-oxo-4-(o-tolyl)pyrazole-1-carbothioate Fenpyrazamine C17H21N3O2S n1(c(c(c(=O)n1C(C)C)c1ccccc1C)N)C(=O)SCC=C InChI=1S/C17H21N3O2S/c1-5-10-23-17(22)20-15(18)14(16(21)19(20)11(2)3)13-9-7-6-8-12(13)4/h5-9,11H,1,10,18H2,2-4H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Negative RMS: Austria Fenpyrazamine (S-2188) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyrazamine 27Jan2012 2012 doi:10.2903/j.efsa.2012.2496
+Fenpyrazamine 473798-59-3 single chemical entity Component is identical to the substance Fenpyrazamine 473798-59-3 S-allyl 5-amino-2,3-dihydro-2-isopropyl-3-oxo-4-(o-tolyl)pyrazole-1-carbothioate Fenpyrazamine C17H21N3O2S n1(c(c(c(=O)n1C(C)C)c1ccccc1C)N)C(=O)SCC=C InChI=1S/C17H21N3O2S/c1-5-10-23-17(22)20-15(18)14(16(21)19(20)11(2)3)13-9-7-6-8-12(13)4/h5-9,11H,1,10,18H2,2-4H3 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: Austria Fenpyrazamine (S-2188) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyrazamine 27Jan2012 2012 doi:10.2903/j.efsa.2012.2496
+Fenpyrazamine 473798-59-3 single chemical entity Component is identical to the substance Fenpyrazamine 473798-59-3 S-allyl 5-amino-2,3-dihydro-2-isopropyl-3-oxo-4-(o-tolyl)pyrazole-1-carbothioate Fenpyrazamine C17H21N3O2S n1(c(c(c(=O)n1C(C)C)c1ccccc1C)N)C(=O)SCC=C InChI=1S/C17H21N3O2S/c1-5-10-23-17(22)20-15(18)14(16(21)19(20)11(2)3)13-9-7-6-8-12(13)4/h5-9,11H,1,10,18H2,2-4H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity$indirect-toxicokinetic investigations RMS: Austria Fenpyrazamine (S-2188) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyrazamine 27Jan2012 2012 doi:10.2903/j.efsa.2012.2496
+Fenpyrazamine 473798-59-3 single chemical entity Component is identical to the substance Fenpyrazamine 473798-59-3 S-allyl 5-amino-2,3-dihydro-2-isopropyl-3-oxo-4-(o-tolyl)pyrazole-1-carbothioate Fenpyrazamine C17H21N3O2S n1(c(c(c(=O)n1C(C)C)c1ccccc1C)N)C(=O)SCC=C InChI=1S/C17H21N3O2S/c1-5-10-23-17(22)20-15(18)14(16(21)19(20)11(2)3)13-9-7-6-8-12(13)4/h5-9,11H,1,10,18H2,2-4H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 48.0000000000 h yes, concurrent vehicle not applicable Negative indirect evidence-systemic toxicity$indirect-toxicokinetic investigations RMS: Austria Fenpyrazamine (S-2188) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyrazamine 27Jan2012 2012 doi:10.2903/j.efsa.2012.2496
+Fenpyrazamine 473798-59-3 single chemical entity Component is a metabolite of the substance 5-Amino-1,2-dihydro-2-isopropyl-4-(otolyl) pyrazol-3-one 5-amino-4-(2-methylphenyl)-2-(propan-2-yl)-1,2-dihydro-3H-pyrazol-3-one Not in list C13H17N3O O=C2C(c1ccccc1C)=C(N)NN2C(C)C InChI=1S/C13H17N3O/c1-8(2)16-13(17)11(12(14)15-16)10-7-5-4-6-9(10)3/h4-8,15H,14H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Austria Fenpyrazamine (S-2188) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyrazamine 27Jan2012 2012 doi:10.2903/j.efsa.2012.2496
+Fenpyrazamine 473798-59-3 single chemical entity Component is a metabolite of the substance 5-Amino-1,2-dihydro-2-isopropyl-4-(otolyl) pyrazol-3-one 5-amino-4-(2-methylphenyl)-2-(propan-2-yl)-1,2-dihydro-3H-pyrazol-3-one Not in list C13H17N3O O=C2C(c1ccccc1C)=C(N)NN2C(C)C InChI=1S/C13H17N3O/c1-8(2)16-13(17)11(12(14)15-16)10-7-5-4-6-9(10)3/h4-8,15H,14H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Austria Fenpyrazamine (S-2188) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyrazamine 27Jan2012 2012 doi:10.2903/j.efsa.2012.2496
+Fenpyrazamine 473798-59-3 single chemical entity Component is a metabolite of the substance 5-Amino-1,2-dihydro-2-isopropyl-4-(otolyl) pyrazol-3-one 5-amino-4-(2-methylphenyl)-2-(propan-2-yl)-1,2-dihydro-3H-pyrazol-3-one Not in list C13H17N3O O=C2C(c1ccccc1C)=C(N)NN2C(C)C InChI=1S/C13H17N3O/c1-8(2)16-13(17)11(12(14)15-16)10-7-5-4-6-9(10)3/h4-8,15H,14H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Austria Fenpyrazamine (S-2188) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyrazamine 27Jan2012 2012 doi:10.2903/j.efsa.2012.2496
+Fenpyrazamine 473798-59-3 single chemical entity Component is a metabolite of the substance 5-Amino-1,2-dihydro-2-isopropyl-4-(otolyl) pyrazol-3-one 5-amino-4-(2-methylphenyl)-2-(propan-2-yl)-1,2-dihydro-3H-pyrazol-3-one Not in list C13H17N3O O=C2C(c1ccccc1C)=C(N)NN2C(C)C InChI=1S/C13H17N3O/c1-8(2)16-13(17)11(12(14)15-16)10-7-5-4-6-9(10)3/h4-8,15H,14H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Austria Fenpyrazamine (S-2188) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyrazamine 27Jan2012 2012 doi:10.2903/j.efsa.2012.2496
+Fenpyrazamine 473798-59-3 single chemical entity Component is a metabolite of the substance 5-Amino-1,2-dihydro-2-isopropyl-4-(otolyl) pyrazol-3-one 5-amino-4-(2-methylphenyl)-2-(propan-2-yl)-1,2-dihydro-3H-pyrazol-3-one Not in list C13H17N3O O=C2C(c1ccccc1C)=C(N)NN2C(C)C InChI=1S/C13H17N3O/c1-8(2)16-13(17)11(12(14)15-16)10-7-5-4-6-9(10)3/h4-8,15H,14H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Austria Fenpyrazamine (S-2188) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyrazamine 27Jan2012 2012 doi:10.2903/j.efsa.2012.2496
+Fenpyrazamine 473798-59-3 single chemical entity Component is a metabolite of the substance 5-Amino-1,2-dihydro-2-isopropyl-4-(otolyl) pyrazol-3-one 5-amino-4-(2-methylphenyl)-2-(propan-2-yl)-1,2-dihydro-3H-pyrazol-3-one Not in list C13H17N3O O=C2C(c1ccccc1C)=C(N)NN2C(C)C InChI=1S/C13H17N3O/c1-8(2)16-13(17)11(12(14)15-16)10-7-5-4-6-9(10)3/h4-8,15H,14H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Austria Fenpyrazamine (S-2188) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyrazamine 27Jan2012 2012 doi:10.2903/j.efsa.2012.2496
+Fenpyrazamine 473798-59-3 single chemical entity Component is a metabolite of the substance 5-Amino-1,2-dihydro-2-isopropyl-4-(otolyl) pyrazol-3-one 5-amino-4-(2-methylphenyl)-2-(propan-2-yl)-1,2-dihydro-3H-pyrazol-3-one Not in list C13H17N3O O=C2C(c1ccccc1C)=C(N)NN2C(C)C InChI=1S/C13H17N3O/c1-8(2)16-13(17)11(12(14)15-16)10-7-5-4-6-9(10)3/h4-8,15H,14H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Austria Fenpyrazamine (S-2188) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyrazamine 27Jan2012 2012 doi:10.2903/j.efsa.2012.2496
+Fenpyrazamine 473798-59-3 single chemical entity Component is a metabolite of the substance 5-Amino-1,2-dihydro-2-isopropyl-4-(otolyl) pyrazol-3-one 5-amino-4-(2-methylphenyl)-2-(propan-2-yl)-1,2-dihydro-3H-pyrazol-3-one Not in list C13H17N3O O=C2C(c1ccccc1C)=C(N)NN2C(C)C InChI=1S/C13H17N3O/c1-8(2)16-13(17)11(12(14)15-16)10-7-5-4-6-9(10)3/h4-8,15H,14H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Austria Fenpyrazamine (S-2188) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyrazamine 27Jan2012 2012 doi:10.2903/j.efsa.2012.2496
+Fenpyrazamine 473798-59-3 single chemical entity Component is a metabolite of the substance 5-Amino-1,2-dihydro-2-isopropyl-4-(otolyl) pyrazol-3-one 5-amino-4-(2-methylphenyl)-2-(propan-2-yl)-1,2-dihydro-3H-pyrazol-3-one Not in list C13H17N3O O=C2C(c1ccccc1C)=C(N)NN2C(C)C InChI=1S/C13H17N3O/c1-8(2)16-13(17)11(12(14)15-16)10-7-5-4-6-9(10)3/h4-8,15H,14H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Austria Fenpyrazamine (S-2188) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyrazamine 27Jan2012 2012 doi:10.2903/j.efsa.2012.2496
+Fenpyrazamine 473798-59-3 single chemical entity Component is a metabolite of the substance 5-Amino-1,2-dihydro-2-isopropyl-4-(otolyl) pyrazol-3-one 5-amino-4-(2-methylphenyl)-2-(propan-2-yl)-1,2-dihydro-3H-pyrazol-3-one Not in list C13H17N3O O=C2C(c1ccccc1C)=C(N)NN2C(C)C InChI=1S/C13H17N3O/c1-8(2)16-13(17)11(12(14)15-16)10-7-5-4-6-9(10)3/h4-8,15H,14H2,1-3H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Austria Fenpyrazamine (S-2188) 2011 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyrazamine 27Jan2012 2012 doi:10.2903/j.efsa.2012.2496
+Haloxyfop-P 95977-29-0 single chemical entity Component is identical to the substance Haloxyfop-P 95977-29-0 (2R)-2-(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy)propanoic acid Haloxyfop-P C15H11ClF3NO4 O=C(O)[C@@H](C)Oc1ccc(cc1)Oc2ncc(cc2Cl)C(F)(F)F InChI=1S/C15H11ClF3NO4/c1-8(14(21)22)23-10-2-4-11(5-3-10)24-13-12(16)6-9(7-20-13)15(17,18)19/h2-8H,1H3,(H,21,22)/t8-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Denmark Haloxyfop-R 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Haloxyfop-P 95977-29-0 single chemical entity Component is identical to the substance Haloxyfop-P 95977-29-0 (2R)-2-(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy)propanoic acid Haloxyfop-P C15H11ClF3NO4 O=C(O)[C@@H](C)Oc1ccc(cc1)Oc2ncc(cc2Cl)C(F)(F)F InChI=1S/C15H11ClF3NO4/c1-8(14(21)22)23-10-2-4-11(5-3-10)24-13-12(16)6-9(7-20-13)15(17,18)19/h2-8H,1H3,(H,21,22)/t8-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Denmark Haloxyfop-R 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Haloxyfop-P 95977-29-0 single chemical entity Component is identical to the substance Haloxyfop-P 95977-29-0 (2R)-2-(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy)propanoic acid Haloxyfop-P C15H11ClF3NO4 O=C(O)[C@@H](C)Oc1ccc(cc1)Oc2ncc(cc2Cl)C(F)(F)F InChI=1S/C15H11ClF3NO4/c1-8(14(21)22)23-10-2-4-11(5-3-10)24-13-12(16)6-9(7-20-13)15(17,18)19/h2-8H,1H3,(H,21,22)/t8-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Denmark Haloxyfop-R 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Haloxyfop-P 95977-29-0 single chemical entity Component is identical to the substance Haloxyfop-P 95977-29-0 (2R)-2-(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy)propanoic acid Haloxyfop-P C15H11ClF3NO4 O=C(O)[C@@H](C)Oc1ccc(cc1)Oc2ncc(cc2Cl)C(F)(F)F InChI=1S/C15H11ClF3NO4/c1-8(14(21)22)23-10-2-4-11(5-3-10)24-13-12(16)6-9(7-20-13)15(17,18)19/h2-8H,1H3,(H,21,22)/t8-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Denmark Haloxyfop-R 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Haloxyfop-P 95977-29-0 single chemical entity Component is identical to the substance Haloxyfop-P 95977-29-0 (2R)-2-(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy)propanoic acid Haloxyfop-P C15H11ClF3NO4 O=C(O)[C@@H](C)Oc1ccc(cc1)Oc2ncc(cc2Cl)C(F)(F)F InChI=1S/C15H11ClF3NO4/c1-8(14(21)22)23-10-2-4-11(5-3-10)24-13-12(16)6-9(7-20-13)15(17,18)19/h2-8H,1H3,(H,21,22)/t8-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Denmark Haloxyfop-R 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Haloxyfop-P 95977-29-0 single chemical entity Component is identical to the substance Haloxyfop-P 95977-29-0 (2R)-2-(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy)propanoic acid Haloxyfop-P C15H11ClF3NO4 O=C(O)[C@@H](C)Oc1ccc(cc1)Oc2ncc(cc2Cl)C(F)(F)F InChI=1S/C15H11ClF3NO4/c1-8(14(21)22)23-10-2-4-11(5-3-10)24-13-12(16)6-9(7-20-13)15(17,18)19/h2-8H,1H3,(H,21,22)/t8-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Denmark Haloxyfop-R 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Haloxyfop-P 95977-29-0 single chemical entity Component is identical to the substance Haloxyfop-P 95977-29-0 (2R)-2-(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy)propanoic acid Haloxyfop-P C15H11ClF3NO4 O=C(O)[C@@H](C)Oc1ccc(cc1)Oc2ncc(cc2Cl)C(F)(F)F InChI=1S/C15H11ClF3NO4/c1-8(14(21)22)23-10-2-4-11(5-3-10)24-13-12(16)6-9(7-20-13)15(17,18)19/h2-8H,1H3,(H,21,22)/t8-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Denmark Haloxyfop-R 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Haloxyfop-P 95977-29-0 single chemical entity Component is identical to the substance Haloxyfop-P 95977-29-0 (2R)-2-(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy)propanoic acid Haloxyfop-P C15H11ClF3NO4 O=C(O)[C@@H](C)Oc1ccc(cc1)Oc2ncc(cc2Cl)C(F)(F)F InChI=1S/C15H11ClF3NO4/c1-8(14(21)22)23-10-2-4-11(5-3-10)24-13-12(16)6-9(7-20-13)15(17,18)19/h2-8H,1H3,(H,21,22)/t8-/m1/s1 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Denmark Haloxyfop-R 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Haloxyfop-P 95977-29-0 single chemical entity Component is part of a group assessment Haloxyfop-P-methyl ester 406-250-0 72619-32-0 Methyl 2-[4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate Not in list C16H13ClF3NO4 CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=N2)C(F)(F)F)Cl InChI=1S/C16H13ClF3NO4/c1-9(15(22)23-2)24-11-3-5-12(6-4-11)25-14-13(17)7-10(8-21-14)16(18,19)20/h3-9H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Denmark Haloxyfop-R 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Haloxyfop-P 95977-29-0 single chemical entity Component is part of a group assessment Haloxyfop-P-methyl ester 406-250-0 72619-32-0 Methyl 2-[4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate Not in list C16H13ClF3NO4 CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=N2)C(F)(F)F)Cl InChI=1S/C16H13ClF3NO4/c1-9(15(22)23-2)24-11-3-5-12(6-4-11)25-14-13(17)7-10(8-21-14)16(18,19)20/h3-9H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Denmark Haloxyfop-R 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Haloxyfop-P 95977-29-0 single chemical entity Component is part of a group assessment Haloxyfop-P-methyl ester 406-250-0 72619-32-0 Methyl 2-[4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate Not in list C16H13ClF3NO4 CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=N2)C(F)(F)F)Cl InChI=1S/C16H13ClF3NO4/c1-9(15(22)23-2)24-11-3-5-12(6-4-11)25-14-13(17)7-10(8-21-14)16(18,19)20/h3-9H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Denmark Haloxyfop-R 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Haloxyfop-P 95977-29-0 single chemical entity Component is part of a group assessment Haloxyfop-P-methyl ester 406-250-0 72619-32-0 Methyl 2-[4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate Not in list C16H13ClF3NO4 CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=N2)C(F)(F)F)Cl InChI=1S/C16H13ClF3NO4/c1-9(15(22)23-2)24-11-3-5-12(6-4-11)25-14-13(17)7-10(8-21-14)16(18,19)20/h3-9H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Denmark Haloxyfop-R 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Haloxyfop-P 95977-29-0 single chemical entity Component is part of a group assessment Haloxyfop-P-methyl ester 406-250-0 72619-32-0 Methyl 2-[4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate Not in list C16H13ClF3NO4 CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=N2)C(F)(F)F)Cl InChI=1S/C16H13ClF3NO4/c1-9(15(22)23-2)24-11-3-5-12(6-4-11)25-14-13(17)7-10(8-21-14)16(18,19)20/h3-9H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Denmark Haloxyfop-R 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Haloxyfop-P 95977-29-0 single chemical entity Component is part of a group assessment Haloxyfop-P-methyl ester 406-250-0 72619-32-0 Methyl 2-[4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate Not in list C16H13ClF3NO4 CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=N2)C(F)(F)F)Cl InChI=1S/C16H13ClF3NO4/c1-9(15(22)23-2)24-11-3-5-12(6-4-11)25-14-13(17)7-10(8-21-14)16(18,19)20/h3-9H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Denmark Haloxyfop-R 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Haloxyfop-P 95977-29-0 single chemical entity Component is part of a group assessment Haloxyfop-P-methyl ester 406-250-0 72619-32-0 Methyl 2-[4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate Not in list C16H13ClF3NO4 CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=N2)C(F)(F)F)Cl InChI=1S/C16H13ClF3NO4/c1-9(15(22)23-2)24-11-3-5-12(6-4-11)25-14-13(17)7-10(8-21-14)16(18,19)20/h3-9H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Denmark Haloxyfop-R 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Haloxyfop-P 95977-29-0 single chemical entity Component is part of a group assessment Haloxyfop-P-methyl ester 406-250-0 72619-32-0 Methyl 2-[4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate Not in list C16H13ClF3NO4 CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=N2)C(F)(F)F)Cl InChI=1S/C16H13ClF3NO4/c1-9(15(22)23-2)24-11-3-5-12(6-4-11)25-14-13(17)7-10(8-21-14)16(18,19)20/h3-9H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Denmark Haloxyfop-R 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Haloxyfop-P 95977-29-0 single chemical entity Component is part of a group assessment Haloxyfop-P-methyl ester 406-250-0 72619-32-0 Methyl 2-[4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate Not in list C16H13ClF3NO4 CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=N2)C(F)(F)F)Cl InChI=1S/C16H13ClF3NO4/c1-9(15(22)23-2)24-11-3-5-12(6-4-11)25-14-13(17)7-10(8-21-14)16(18,19)20/h3-9H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Denmark Haloxyfop-R 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Haloxyfop-P 95977-29-0 single chemical entity Component is part of a group assessment Haloxyfop-P-methyl ester 406-250-0 72619-32-0 Methyl 2-[4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate Not in list C16H13ClF3NO4 CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=N2)C(F)(F)F)Cl InChI=1S/C16H13ClF3NO4/c1-9(15(22)23-2)24-11-3-5-12(6-4-11)25-14-13(17)7-10(8-21-14)16(18,19)20/h3-9H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Denmark Haloxyfop-R 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Haloxyfop-P 95977-29-0 single chemical entity Component is part of a mixture or forumlation Racemic Haloxyfop Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Denmark Haloxyfop-R 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Haloxyfop-P 95977-29-0 single chemical entity Component is part of a mixture or forumlation Racemic Haloxyfop Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Denmark Haloxyfop-R 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Haloxyfop-P 95977-29-0 single chemical entity Component is part of a mixture or forumlation Racemic Haloxyfop Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Denmark Haloxyfop-R 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Haloxyfop-P 95977-29-0 single chemical entity Component is part of a mixture or forumlation Racemic Haloxyfop Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Denmark Haloxyfop-R 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Haloxyfop-P 95977-29-0 single chemical entity Component is part of a mixture or forumlation Racemic Haloxyfop Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Denmark Haloxyfop-R 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Haloxyfop-P 95977-29-0 single chemical entity Component is part of a mixture or forumlation Racemic Haloxyfop Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Denmark Haloxyfop-R 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Haloxyfop-P 95977-29-0 single chemical entity Component is part of a mixture or forumlation Racemic Haloxyfop Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Denmark Haloxyfop-R 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Haloxyfop-P 95977-29-0 single chemical entity Component is part of a mixture or forumlation Racemic Haloxyfop Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Denmark Haloxyfop-R 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Haloxyfop-P 95977-29-0 single chemical entity Component is part of a mixture or forumlation Racemic Haloxyfop Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Denmark Haloxyfop-R 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Haloxyfop-P 95977-29-0 single chemical entity Component is part of a mixture or forumlation Racemic Haloxyfop Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Denmark Haloxyfop-R 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Haloxyfop-P 95977-29-0 single chemical entity Component is part of a mixture or forumlation Racemic Haloxyfop Not in list organic no structure gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes with Ambiguous RMS: Denmark Haloxyfop-R 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Haloxyfop-P 95977-29-0 single chemical entity Component is part of a mixture or forumlation Racemic Haloxyfop Not in list organic no structure gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: Denmark Haloxyfop-R 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Haloxyfop-P 95977-29-0 single chemical entity Component is identical to the substance Haloxyfop-P 95977-29-0 (2R)-2-(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy)propanoic acid Haloxyfop-P C15H11ClF3NO4 O=C(O)[C@@H](C)Oc1ccc(cc1)Oc2ncc(cc2Cl)C(F)(F)F InChI=1S/C15H11ClF3NO4/c1-8(14(21)22)23-10-2-4-11(5-3-10)24-13-12(16)6-9(7-20-13)15(17,18)19/h2-8H,1H3,(H,21,22)/t8-/m1/s1 organic compound Other Other DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Rat (as animal) hepatocytes Not reported yes without Negative RMS: Denmark Haloxyfop-R 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Haloxyfop-P 95977-29-0 single chemical entity Component is part of a mixture or forumlation Racemic Haloxyfop Not in list organic no structure DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Rat (as animal) hepatocytes Not reported yes without Negative RMS: Denmark Haloxyfop-R 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Haloxyfop-P 95977-29-0 single chemical entity Component is part of a mixture or forumlation Racemic Haloxyfop Not in list organic no structure chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: Denmark Haloxyfop-R 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Haloxyfop-P 95977-29-0 single chemical entity Component is part of a mixture or forumlation Racemic Haloxyfop Not in list organic no structure chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: Denmark Haloxyfop-R 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Haloxyfop-P 95977-29-0 single chemical entity Component is identical to the substance Haloxyfop-P 95977-29-0 (2R)-2-(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy)propanoic acid Haloxyfop-P C15H11ClF3NO4 O=C(O)[C@@H](C)Oc1ccc(cc1)Oc2ncc(cc2Cl)C(F)(F)F InChI=1S/C15H11ClF3NO4/c1-8(14(21)22)23-10-2-4-11(5-3-10)24-13-12(16)6-9(7-20-13)15(17,18)19/h2-8H,1H3,(H,21,22)/t8-/m1/s1 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Rat (as animal) lymphocytes Not reported yes with Negative RMS: Denmark Haloxyfop-R 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Haloxyfop-P 95977-29-0 single chemical entity Component is identical to the substance Haloxyfop-P 95977-29-0 (2R)-2-(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy)propanoic acid Haloxyfop-P C15H11ClF3NO4 O=C(O)[C@@H](C)Oc1ccc(cc1)Oc2ncc(cc2Cl)C(F)(F)F InChI=1S/C15H11ClF3NO4/c1-8(14(21)22)23-10-2-4-11(5-3-10)24-13-12(16)6-9(7-20-13)15(17,18)19/h2-8H,1H3,(H,21,22)/t8-/m1/s1 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Rat (as animal) lymphocytes Not reported yes without Negative RMS: Denmark Haloxyfop-R 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Haloxyfop-P 95977-29-0 single chemical entity Component is part of a group assessment Haloxyfop-P-methyl ester 406-250-0 72619-32-0 Methyl 2-[4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate Not in list C16H13ClF3NO4 CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=N2)C(F)(F)F)Cl InChI=1S/C16H13ClF3NO4/c1-9(15(22)23-2)24-11-3-5-12(6-4-11)25-14-13(17)7-10(8-21-14)16(18,19)20/h3-9H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Rat (as animal) lymphocytes Not reported yes without Negative RMS: Denmark Haloxyfop-R 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Haloxyfop-P 95977-29-0 single chemical entity Component is part of a group assessment Haloxyfop-P-methyl ester 406-250-0 72619-32-0 Methyl 2-[4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate Not in list C16H13ClF3NO4 CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=N2)C(F)(F)F)Cl InChI=1S/C16H13ClF3NO4/c1-9(15(22)23-2)24-11-3-5-12(6-4-11)25-14-13(17)7-10(8-21-14)16(18,19)20/h3-9H,1-2H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Rat (as animal) lymphocytes Not reported yes with Negative RMS: Denmark Haloxyfop-R 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Haloxyfop-P 95977-29-0 single chemical entity Component is part of a mixture or forumlation Racemic Haloxyfop Not in list organic no structure chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable Rat (as animal) Sprague-Dawley 10 Male/Female oral: feed 42.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Denmark Haloxyfop-R 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Haloxyfop-P 95977-29-0 single chemical entity Component is part of a mixture or forumlation Racemic Haloxyfop Not in list organic no structure chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable Rat (as animal) Sprague-Dawley 10 Male/Female oral: feed 30.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Denmark Haloxyfop-R 2004 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Haloxyfop-P 95977-29-0 single chemical entity Component is a metabolite of the substance 3-chloro-5-(trifluoromethyl)pyridin-2-ol 76041-71-9 3-chloro-5-(trifluoromethyl)-1H-pyridin-2-one Not in list C6H3ClF3NO C1=C(C(=O)NC=C1C(F)(F)F)Cl InChI=1S/C6H3ClF3NO/c7-4-1-3(6(8,9)10)2-11-5(4)12/h1-2H,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Denmark Haloxyfop-R (Addendum ) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Haloxyfop-P 95977-29-0 single chemical entity Component is a metabolite of the substance 3-chloro-5-(trifluoromethyl)pyridin-2-ol 76041-71-9 3-chloro-5-(trifluoromethyl)-1H-pyridin-2-one Not in list C6H3ClF3NO C1=C(C(=O)NC=C1C(F)(F)F)Cl InChI=1S/C6H3ClF3NO/c7-4-1-3(6(8,9)10)2-11-5(4)12/h1-2H,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Denmark Haloxyfop-R (Addendum ) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Haloxyfop-P 95977-29-0 single chemical entity Component is a metabolite of the substance 3-chloro-5-(trifluoromethyl)pyridin-2-ol 76041-71-9 3-chloro-5-(trifluoromethyl)-1H-pyridin-2-one Not in list C6H3ClF3NO C1=C(C(=O)NC=C1C(F)(F)F)Cl InChI=1S/C6H3ClF3NO/c7-4-1-3(6(8,9)10)2-11-5(4)12/h1-2H,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Positive RMS: Denmark Haloxyfop-R (Addendum ) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Haloxyfop-P 95977-29-0 single chemical entity Component is a metabolite of the substance 3-chloro-5-(trifluoromethyl)pyridin-2-ol 76041-71-9 3-chloro-5-(trifluoromethyl)-1H-pyridin-2-one Not in list C6H3ClF3NO C1=C(C(=O)NC=C1C(F)(F)F)Cl InChI=1S/C6H3ClF3NO/c7-4-1-3(6(8,9)10)2-11-5(4)12/h1-2H,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Denmark Haloxyfop-R (Addendum ) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Haloxyfop-P 95977-29-0 single chemical entity Component is a metabolite of the substance 3-chloro-5-(trifluoromethyl)pyridin-2-ol 76041-71-9 3-chloro-5-(trifluoromethyl)-1H-pyridin-2-one Not in list C6H3ClF3NO C1=C(C(=O)NC=C1C(F)(F)F)Cl InChI=1S/C6H3ClF3NO/c7-4-1-3(6(8,9)10)2-11-5(4)12/h1-2H,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Positive RMS: Denmark Haloxyfop-R (Addendum ) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Haloxyfop-P 95977-29-0 single chemical entity Component is a metabolite of the substance 3-chloro-5-(trifluoromethyl)pyridin-2-ol 76041-71-9 3-chloro-5-(trifluoromethyl)-1H-pyridin-2-one Not in list C6H3ClF3NO C1=C(C(=O)NC=C1C(F)(F)F)Cl InChI=1S/C6H3ClF3NO/c7-4-1-3(6(8,9)10)2-11-5(4)12/h1-2H,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Denmark Haloxyfop-R (Addendum ) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Haloxyfop-P 95977-29-0 single chemical entity Component is a metabolite of the substance 3-chloro-5-(trifluoromethyl)pyridin-2-ol 76041-71-9 3-chloro-5-(trifluoromethyl)-1H-pyridin-2-one Not in list C6H3ClF3NO C1=C(C(=O)NC=C1C(F)(F)F)Cl InChI=1S/C6H3ClF3NO/c7-4-1-3(6(8,9)10)2-11-5(4)12/h1-2H,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Denmark Haloxyfop-R (Addendum ) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Haloxyfop-P 95977-29-0 single chemical entity Component is a metabolite of the substance 3-chloro-5-(trifluoromethyl)pyridin-2-ol 76041-71-9 3-chloro-5-(trifluoromethyl)-1H-pyridin-2-one Not in list C6H3ClF3NO C1=C(C(=O)NC=C1C(F)(F)F)Cl InChI=1S/C6H3ClF3NO/c7-4-1-3(6(8,9)10)2-11-5(4)12/h1-2H,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Positive RMS: Denmark Haloxyfop-R (Addendum ) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Haloxyfop-P 95977-29-0 single chemical entity Component is a metabolite of the substance 3-chloro-5-(trifluoromethyl)pyridin-2-ol 76041-71-9 3-chloro-5-(trifluoromethyl)-1H-pyridin-2-one Not in list C6H3ClF3NO C1=C(C(=O)NC=C1C(F)(F)F)Cl InChI=1S/C6H3ClF3NO/c7-4-1-3(6(8,9)10)2-11-5(4)12/h1-2H,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Denmark Haloxyfop-R (Addendum ) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Haloxyfop-P 95977-29-0 single chemical entity Component is a metabolite of the substance 3-chloro-5-(trifluoromethyl)pyridin-2-ol 76041-71-9 3-chloro-5-(trifluoromethyl)-1H-pyridin-2-one Not in list C6H3ClF3NO C1=C(C(=O)NC=C1C(F)(F)F)Cl InChI=1S/C6H3ClF3NO/c7-4-1-3(6(8,9)10)2-11-5(4)12/h1-2H,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Denmark Haloxyfop-R (Addendum ) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Haloxyfop-P 95977-29-0 single chemical entity Component is a metabolite of the substance 3-chloro-1-methyl-5-(trifluoromethyl)-2(1H)-pyridinone 3-chloro-1-methyl-5-(trifluoromethyl)-2(1H)-pyridinone Not in list C7H5ClF3NO ClC1=CC(=CN(C)C1=O)C(F)(F)F InChI=1/C7H5ClF3NO/c1-12-3-4(7(9,10)11)2-5(8)6(12)13/h2-3H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Denmark Haloxyfop-R (Addendum ) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Haloxyfop-P 95977-29-0 single chemical entity Component is a metabolite of the substance 3-chloro-1-methyl-5-(trifluoromethyl)-2(1H)-pyridinone 3-chloro-1-methyl-5-(trifluoromethyl)-2(1H)-pyridinone Not in list C7H5ClF3NO ClC1=CC(=CN(C)C1=O)C(F)(F)F InChI=1/C7H5ClF3NO/c1-12-3-4(7(9,10)11)2-5(8)6(12)13/h2-3H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Denmark Haloxyfop-R (Addendum ) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Haloxyfop-P 95977-29-0 single chemical entity Component is a metabolite of the substance 3-chloro-1-methyl-5-(trifluoromethyl)-2(1H)-pyridinone 3-chloro-1-methyl-5-(trifluoromethyl)-2(1H)-pyridinone Not in list C7H5ClF3NO ClC1=CC(=CN(C)C1=O)C(F)(F)F InChI=1/C7H5ClF3NO/c1-12-3-4(7(9,10)11)2-5(8)6(12)13/h2-3H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Denmark Haloxyfop-R (Addendum ) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Haloxyfop-P 95977-29-0 single chemical entity Component is a metabolite of the substance 3-chloro-1-methyl-5-(trifluoromethyl)-2(1H)-pyridinone 3-chloro-1-methyl-5-(trifluoromethyl)-2(1H)-pyridinone Not in list C7H5ClF3NO ClC1=CC(=CN(C)C1=O)C(F)(F)F InChI=1/C7H5ClF3NO/c1-12-3-4(7(9,10)11)2-5(8)6(12)13/h2-3H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Denmark Haloxyfop-R (Addendum ) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Haloxyfop-P 95977-29-0 single chemical entity Component is a metabolite of the substance 3-chloro-1-methyl-5-(trifluoromethyl)-2(1H)-pyridinone 3-chloro-1-methyl-5-(trifluoromethyl)-2(1H)-pyridinone Not in list C7H5ClF3NO ClC1=CC(=CN(C)C1=O)C(F)(F)F InChI=1/C7H5ClF3NO/c1-12-3-4(7(9,10)11)2-5(8)6(12)13/h2-3H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Denmark Haloxyfop-R (Addendum ) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Haloxyfop-P 95977-29-0 single chemical entity Component is a metabolite of the substance 3-chloro-1-methyl-5-(trifluoromethyl)-2(1H)-pyridinone 3-chloro-1-methyl-5-(trifluoromethyl)-2(1H)-pyridinone Not in list C7H5ClF3NO ClC1=CC(=CN(C)C1=O)C(F)(F)F InChI=1/C7H5ClF3NO/c1-12-3-4(7(9,10)11)2-5(8)6(12)13/h2-3H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Denmark Haloxyfop-R (Addendum ) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Haloxyfop-P 95977-29-0 single chemical entity Component is a metabolite of the substance 3-chloro-1-methyl-5-(trifluoromethyl)-2(1H)-pyridinone 3-chloro-1-methyl-5-(trifluoromethyl)-2(1H)-pyridinone Not in list C7H5ClF3NO ClC1=CC(=CN(C)C1=O)C(F)(F)F InChI=1/C7H5ClF3NO/c1-12-3-4(7(9,10)11)2-5(8)6(12)13/h2-3H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Denmark Haloxyfop-R (Addendum ) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Haloxyfop-P 95977-29-0 single chemical entity Component is a metabolite of the substance 3-chloro-1-methyl-5-(trifluoromethyl)-2(1H)-pyridinone 3-chloro-1-methyl-5-(trifluoromethyl)-2(1H)-pyridinone Not in list C7H5ClF3NO ClC1=CC(=CN(C)C1=O)C(F)(F)F InChI=1/C7H5ClF3NO/c1-12-3-4(7(9,10)11)2-5(8)6(12)13/h2-3H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Denmark Haloxyfop-R (Addendum ) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Haloxyfop-P 95977-29-0 single chemical entity Component is a metabolite of the substance 3-chloro-1-methyl-5-(trifluoromethyl)-2(1H)-pyridinone 3-chloro-1-methyl-5-(trifluoromethyl)-2(1H)-pyridinone Not in list C7H5ClF3NO ClC1=CC(=CN(C)C1=O)C(F)(F)F InChI=1/C7H5ClF3NO/c1-12-3-4(7(9,10)11)2-5(8)6(12)13/h2-3H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Denmark Haloxyfop-R (Addendum ) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Haloxyfop-P 95977-29-0 single chemical entity Component is a metabolite of the substance 3-chloro-1-methyl-5-(trifluoromethyl)-2(1H)-pyridinone 3-chloro-1-methyl-5-(trifluoromethyl)-2(1H)-pyridinone Not in list C7H5ClF3NO ClC1=CC(=CN(C)C1=O)C(F)(F)F InChI=1/C7H5ClF3NO/c1-12-3-4(7(9,10)11)2-5(8)6(12)13/h2-3H,1H3 organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Denmark Haloxyfop-R (Addendum ) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Haloxyfop-P 95977-29-0 single chemical entity Component is a metabolite of the substance 3-chloro-5-(trifluoromethyl)pyridin-2-ol 76041-71-9 3-chloro-5-(trifluoromethyl)-1H-pyridin-2-one Not in list C6H3ClF3NO C1=C(C(=O)NC=C1C(F)(F)F)Cl InChI=1S/C6H3ClF3NO/c7-4-1-3(6(8,9)10)2-11-5(4)12/h1-2H,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: Denmark Haloxyfop-R (Addendum ) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Haloxyfop-P 95977-29-0 single chemical entity Component is a metabolite of the substance 3-chloro-5-(trifluoromethyl)pyridin-2-ol 76041-71-9 3-chloro-5-(trifluoromethyl)-1H-pyridin-2-one Not in list C6H3ClF3NO C1=C(C(=O)NC=C1C(F)(F)F)Cl InChI=1S/C6H3ClF3NO/c7-4-1-3(6(8,9)10)2-11-5(4)12/h1-2H,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: Denmark Haloxyfop-R (Addendum ) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Haloxyfop-P 95977-29-0 single chemical entity Component is a metabolite of the substance 3-chloro-5-(trifluoromethyl)pyridin-2-ol 76041-71-9 3-chloro-5-(trifluoromethyl)-1H-pyridin-2-one Not in list C6H3ClF3NO C1=C(C(=O)NC=C1C(F)(F)F)Cl InChI=1S/C6H3ClF3NO/c7-4-1-3(6(8,9)10)2-11-5(4)12/h1-2H,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Fischer344 Male/Female oral: gavage 16.0000000000 h yes not applicable Negative RMS: Denmark Haloxyfop-R (Addendum ) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Haloxyfop-P 95977-29-0 single chemical entity Component is a metabolite of the substance 3-chloro-5-(trifluoromethyl)pyridin-2-ol 76041-71-9 3-chloro-5-(trifluoromethyl)-1H-pyridin-2-one Not in list C6H3ClF3NO C1=C(C(=O)NC=C1C(F)(F)F)Cl InChI=1S/C6H3ClF3NO/c7-4-1-3(6(8,9)10)2-11-5(4)12/h1-2H,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Fischer344 Male/Female oral: gavage 4.0000000000 h yes not applicable Negative RMS: Denmark Haloxyfop-R (Addendum ) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Haloxyfop-P 95977-29-0 single chemical entity Component is a metabolite of the substance 3-chloro-5-(trifluoromethyl)pyridin-2-ol 76041-71-9 3-chloro-5-(trifluoromethyl)-1H-pyridin-2-one Not in list C6H3ClF3NO C1=C(C(=O)NC=C1C(F)(F)F)Cl InChI=1S/C6H3ClF3NO/c7-4-1-3(6(8,9)10)2-11-5(4)12/h1-2H,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Rat (as animal) lymphocytes Not reported yes without Negative RMS: Denmark Haloxyfop-R (Addendum ) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Haloxyfop-P 95977-29-0 single chemical entity Component is a metabolite of the substance 3-chloro-5-(trifluoromethyl)pyridin-2-ol 76041-71-9 3-chloro-5-(trifluoromethyl)-1H-pyridin-2-one Not in list C6H3ClF3NO C1=C(C(=O)NC=C1C(F)(F)F)Cl InChI=1S/C6H3ClF3NO/c7-4-1-3(6(8,9)10)2-11-5(4)12/h1-2H,(H,11,12) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Rat (as animal) lymphocytes Not reported yes with Negative RMS: Denmark Haloxyfop-R (Addendum ) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P 12Dec2014 2014 doi:10.2903/j.efsa.2014.3931
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is identical to the substance Triflusulfuron-methyl 126535-15-7 Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate Triflusulfuron-Methyl C17H19F3N6O6S CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle without Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is identical to the substance Triflusulfuron-methyl 126535-15-7 Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate Triflusulfuron-Methyl C17H19F3N6O6S CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is identical to the substance Triflusulfuron-methyl 126535-15-7 Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate Triflusulfuron-Methyl C17H19F3N6O6S CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle with Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is identical to the substance Triflusulfuron-methyl 126535-15-7 Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate Triflusulfuron-Methyl C17H19F3N6O6S CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is identical to the substance Triflusulfuron-methyl 126535-15-7 Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate Triflusulfuron-Methyl C17H19F3N6O6S CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is identical to the substance Triflusulfuron-methyl 126535-15-7 Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate Triflusulfuron-Methyl C17H19F3N6O6S CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is identical to the substance Triflusulfuron-methyl 126535-15-7 Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate Triflusulfuron-Methyl C17H19F3N6O6S CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is identical to the substance Triflusulfuron-methyl 126535-15-7 Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate Triflusulfuron-Methyl C17H19F3N6O6S CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is identical to the substance Triflusulfuron-methyl 126535-15-7 Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate Triflusulfuron-Methyl C17H19F3N6O6S CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is identical to the substance Triflusulfuron-methyl 126535-15-7 Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate Triflusulfuron-Methyl C17H19F3N6O6S CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is identical to the substance Triflusulfuron-methyl 126535-15-7 Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate Triflusulfuron-Methyl C17H19F3N6O6S CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is identical to the substance Triflusulfuron-methyl 126535-15-7 Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate Triflusulfuron-Methyl C17H19F3N6O6S CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is identical to the substance Triflusulfuron-methyl 126535-15-7 Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate Triflusulfuron-Methyl C17H19F3N6O6S CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is identical to the substance Triflusulfuron-methyl 126535-15-7 Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate Triflusulfuron-Methyl C17H19F3N6O6S CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is identical to the substance Triflusulfuron-methyl 126535-15-7 Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate Triflusulfuron-Methyl C17H19F3N6O6S CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is identical to the substance Triflusulfuron-methyl 126535-15-7 Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate Triflusulfuron-Methyl C17H19F3N6O6S CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is identical to the substance Triflusulfuron-methyl 126535-15-7 Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate Triflusulfuron-Methyl C17H19F3N6O6S CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is identical to the substance Triflusulfuron-methyl 126535-15-7 Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate Triflusulfuron-Methyl C17H19F3N6O6S CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is identical to the substance Triflusulfuron-methyl 126535-15-7 Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate Triflusulfuron-Methyl C17H19F3N6O6S CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is identical to the substance Triflusulfuron-methyl 126535-15-7 Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate Triflusulfuron-Methyl C17H19F3N6O6S CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is identical to the substance Triflusulfuron-methyl 126535-15-7 Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate Triflusulfuron-Methyl C17H19F3N6O6S CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is identical to the substance Triflusulfuron-methyl 126535-15-7 Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate Triflusulfuron-Methyl C17H19F3N6O6S CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Positive RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is identical to the substance Triflusulfuron-methyl 126535-15-7 Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate Triflusulfuron-Methyl C17H19F3N6O6S CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is identical to the substance Triflusulfuron-methyl 126535-15-7 Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate Triflusulfuron-Methyl C17H19F3N6O6S CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Positive RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is identical to the substance Triflusulfuron-methyl 126535-15-7 Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate Triflusulfuron-Methyl C17H19F3N6O6S CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Positive RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is identical to the substance Triflusulfuron-methyl 126535-15-7 Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate Triflusulfuron-Methyl C17H19F3N6O6S CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle without Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is identical to the substance Triflusulfuron-methyl 126535-15-7 Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate Triflusulfuron-Methyl C17H19F3N6O6S CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes, concurrent vehicle with Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is identical to the substance Triflusulfuron-methyl 126535-15-7 Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate Triflusulfuron-Methyl C17H19F3N6O6S CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: unspecified 72.0000000000 h yes not applicable Negative direct evidence-cytotoxicity RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is identical to the substance Triflusulfuron-methyl 126535-15-7 Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate Triflusulfuron-Methyl C17H19F3N6O6S CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: unspecified 48.0000000000 h yes not applicable Negative direct evidence-cytotoxicity RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is identical to the substance Triflusulfuron-methyl 126535-15-7 Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate Triflusulfuron-Methyl C17H19F3N6O6S CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: unspecified 24.0000000000 h yes not applicable Negative direct evidence-cytotoxicity RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is identical to the substance Triflusulfuron-methyl 126535-15-7 Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate Triflusulfuron-Methyl C17H19F3N6O6S CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Swiss 20 Male/Female oral: unspecified 24.0000000000 h yes not applicable Negative no evidence RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is identical to the substance Triflusulfuron-methyl 126535-15-7 Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate Triflusulfuron-Methyl C17H19F3N6O6S CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Swiss 20 Male/Female oral: unspecified 48.0000000000 h yes not applicable Negative no evidence RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is identical to the substance Triflusulfuron-methyl 126535-15-7 Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate Triflusulfuron-Methyl C17H19F3N6O6S CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration mammalian germ cell cytogenetic assay in vivo According to OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test) No Acceptable House mouse (as animal) ICR 5 Male oral: unspecified 48.0000000000 h no data not applicable Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is identical to the substance Triflusulfuron-methyl 126535-15-7 Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate Triflusulfuron-Methyl C17H19F3N6O6S CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration mammalian germ cell cytogenetic assay in vivo According to OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test) No Acceptable House mouse (as animal) ICR 5 Male oral: unspecified 24.0000000000 h no data not applicable Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is a metabolite of the substance N,N-dimethyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine 415-500-8 145963-84-4 2-N,2-N-dimethyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine Not in list C7H10F3N5O CN(C)C1=NC(=NC(=N1)N)OCC(F)(F)F InChI=1S/C7H10F3N5O/c1-15(2)5-12-4(11)13-6(14-5)16-3-7(8,9)10/h3H2,1-2H3,(H2,11,12,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is a metabolite of the substance N,N-dimethyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine 415-500-8 145963-84-4 2-N,2-N-dimethyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine Not in list C7H10F3N5O CN(C)C1=NC(=NC(=N1)N)OCC(F)(F)F InChI=1S/C7H10F3N5O/c1-15(2)5-12-4(11)13-6(14-5)16-3-7(8,9)10/h3H2,1-2H3,(H2,11,12,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is a metabolite of the substance N,N-dimethyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine 415-500-8 145963-84-4 2-N,2-N-dimethyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine Not in list C7H10F3N5O CN(C)C1=NC(=NC(=N1)N)OCC(F)(F)F InChI=1S/C7H10F3N5O/c1-15(2)5-12-4(11)13-6(14-5)16-3-7(8,9)10/h3H2,1-2H3,(H2,11,12,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is a metabolite of the substance N,N-dimethyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine 415-500-8 145963-84-4 2-N,2-N-dimethyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine Not in list C7H10F3N5O CN(C)C1=NC(=NC(=N1)N)OCC(F)(F)F InChI=1S/C7H10F3N5O/c1-15(2)5-12-4(11)13-6(14-5)16-3-7(8,9)10/h3H2,1-2H3,(H2,11,12,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is a metabolite of the substance N,N-dimethyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine 415-500-8 145963-84-4 2-N,2-N-dimethyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine Not in list C7H10F3N5O CN(C)C1=NC(=NC(=N1)N)OCC(F)(F)F InChI=1S/C7H10F3N5O/c1-15(2)5-12-4(11)13-6(14-5)16-3-7(8,9)10/h3H2,1-2H3,(H2,11,12,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle with Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is a metabolite of the substance N,N-dimethyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine 415-500-8 145963-84-4 2-N,2-N-dimethyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine Not in list C7H10F3N5O CN(C)C1=NC(=NC(=N1)N)OCC(F)(F)F InChI=1S/C7H10F3N5O/c1-15(2)5-12-4(11)13-6(14-5)16-3-7(8,9)10/h3H2,1-2H3,(H2,11,12,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is a metabolite of the substance N,N-dimethyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine 415-500-8 145963-84-4 2-N,2-N-dimethyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine Not in list C7H10F3N5O CN(C)C1=NC(=NC(=N1)N)OCC(F)(F)F InChI=1S/C7H10F3N5O/c1-15(2)5-12-4(11)13-6(14-5)16-3-7(8,9)10/h3H2,1-2H3,(H2,11,12,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle without Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is a metabolite of the substance N,N-dimethyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine 415-500-8 145963-84-4 2-N,2-N-dimethyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine Not in list C7H10F3N5O CN(C)C1=NC(=NC(=N1)N)OCC(F)(F)F InChI=1S/C7H10F3N5O/c1-15(2)5-12-4(11)13-6(14-5)16-3-7(8,9)10/h3H2,1-2H3,(H2,11,12,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is a metabolite of the substance N-methyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine 2-N-methyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine Not in list C6H8F3N5O CNC1=NC(=NC(=N1)N)OCC(F)(F)F InChI=1S/C6H8F3N5O/c1-11-4-12-3(10)13-5(14-4)15-2-6(7,8)9/h2H2,1H3,(H3,10,11,12,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle with Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is a metabolite of the substance N-methyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine 2-N-methyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine Not in list C6H8F3N5O CNC1=NC(=NC(=N1)N)OCC(F)(F)F InChI=1S/C6H8F3N5O/c1-11-4-12-3(10)13-5(14-4)15-2-6(7,8)9/h2H2,1H3,(H3,10,11,12,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is a metabolite of the substance N-methyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine 2-N-methyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine Not in list C6H8F3N5O CNC1=NC(=NC(=N1)N)OCC(F)(F)F InChI=1S/C6H8F3N5O/c1-11-4-12-3(10)13-5(14-4)15-2-6(7,8)9/h2H2,1H3,(H3,10,11,12,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is a metabolite of the substance N-methyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine 2-N-methyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine Not in list C6H8F3N5O CNC1=NC(=NC(=N1)N)OCC(F)(F)F InChI=1S/C6H8F3N5O/c1-11-4-12-3(10)13-5(14-4)15-2-6(7,8)9/h2H2,1H3,(H3,10,11,12,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is a metabolite of the substance N-methyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine 2-N-methyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine Not in list C6H8F3N5O CNC1=NC(=NC(=N1)N)OCC(F)(F)F InChI=1S/C6H8F3N5O/c1-11-4-12-3(10)13-5(14-4)15-2-6(7,8)9/h2H2,1H3,(H3,10,11,12,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is a metabolite of the substance N-methyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine 2-N-methyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine Not in list C6H8F3N5O CNC1=NC(=NC(=N1)N)OCC(F)(F)F InChI=1S/C6H8F3N5O/c1-11-4-12-3(10)13-5(14-4)15-2-6(7,8)9/h2H2,1H3,(H3,10,11,12,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle without Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is a metabolite of the substance N-methyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine 2-N-methyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine Not in list C6H8F3N5O CNC1=NC(=NC(=N1)N)OCC(F)(F)F InChI=1S/C6H8F3N5O/c1-11-4-12-3(10)13-5(14-4)15-2-6(7,8)9/h2H2,1H3,(H3,10,11,12,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is a metabolite of the substance N-methyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine 2-N-methyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine Not in list C6H8F3N5O CNC1=NC(=NC(=N1)N)OCC(F)(F)F InChI=1S/C6H8F3N5O/c1-11-4-12-3(10)13-5(14-4)15-2-6(7,8)9/h2H2,1H3,(H3,10,11,12,13,14) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is a metabolite of the substance 6-(2,2,2-Trifluoroethoxy)-1,3,5-triazine-2,4-diamine 6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine Not in list C5H6F3N5O FC(F)(F)COc1nc(N)nc(N)n1 InChI=1/C5H6F3N5O/c6-5(7,8)1-14-4-12-2(9)11-3(10)13-4/h1H2,(H4,9,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle without Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is a metabolite of the substance 6-(2,2,2-Trifluoroethoxy)-1,3,5-triazine-2,4-diamine 6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine Not in list C5H6F3N5O FC(F)(F)COc1nc(N)nc(N)n1 InChI=1/C5H6F3N5O/c6-5(7,8)1-14-4-12-2(9)11-3(10)13-4/h1H2,(H4,9,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is a metabolite of the substance 6-(2,2,2-Trifluoroethoxy)-1,3,5-triazine-2,4-diamine 6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine Not in list C5H6F3N5O FC(F)(F)COc1nc(N)nc(N)n1 InChI=1/C5H6F3N5O/c6-5(7,8)1-14-4-12-2(9)11-3(10)13-4/h1H2,(H4,9,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is a metabolite of the substance 6-(2,2,2-Trifluoroethoxy)-1,3,5-triazine-2,4-diamine 6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine Not in list C5H6F3N5O FC(F)(F)COc1nc(N)nc(N)n1 InChI=1/C5H6F3N5O/c6-5(7,8)1-14-4-12-2(9)11-3(10)13-4/h1H2,(H4,9,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is a metabolite of the substance 6-(2,2,2-Trifluoroethoxy)-1,3,5-triazine-2,4-diamine 6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine Not in list C5H6F3N5O FC(F)(F)COc1nc(N)nc(N)n1 InChI=1/C5H6F3N5O/c6-5(7,8)1-14-4-12-2(9)11-3(10)13-4/h1H2,(H4,9,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is a metabolite of the substance 6-(2,2,2-Trifluoroethoxy)-1,3,5-triazine-2,4-diamine 6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine Not in list C5H6F3N5O FC(F)(F)COc1nc(N)nc(N)n1 InChI=1/C5H6F3N5O/c6-5(7,8)1-14-4-12-2(9)11-3(10)13-4/h1H2,(H4,9,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is a metabolite of the substance 6-(2,2,2-Trifluoroethoxy)-1,3,5-triazine-2,4-diamine 6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine Not in list C5H6F3N5O FC(F)(F)COc1nc(N)nc(N)n1 InChI=1/C5H6F3N5O/c6-5(7,8)1-14-4-12-2(9)11-3(10)13-4/h1H2,(H4,9,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is a metabolite of the substance 6-(2,2,2-Trifluoroethoxy)-1,3,5-triazine-2,4-diamine 6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine Not in list C5H6F3N5O FC(F)(F)COc1nc(N)nc(N)n1 InChI=1/C5H6F3N5O/c6-5(7,8)1-14-4-12-2(9)11-3(10)13-4/h1H2,(H4,9,10,11,12,13) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle with Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is a metabolite of the substance 6-(2,2,2-Trifluoroethoxy)-1,3,5-triazine-2,4-diamine 6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine Not in list C5H6F3N5O FC(F)(F)COc1nc(N)nc(N)n1 InChI=1/C5H6F3N5O/c6-5(7,8)1-14-4-12-2(9)11-3(10)13-4/h1H2,(H4,9,10,11,12,13) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is a metabolite of the substance 6-(2,2,2-Trifluoroethoxy)-1,3,5-triazine-2,4-diamine 6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine Not in list C5H6F3N5O FC(F)(F)COc1nc(N)nc(N)n1 InChI=1/C5H6F3N5O/c6-5(7,8)1-14-4-12-2(9)11-3(10)13-4/h1H2,(H4,9,10,11,12,13) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is a metabolite of the substance 6-(2,2,2-Trifluoroethoxy)-1,3,5-triazine-2,4-diamine 6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine Not in list C5H6F3N5O FC(F)(F)COc1nc(N)nc(N)n1 InChI=1/C5H6F3N5O/c6-5(7,8)1-14-4-12-2(9)11-3(10)13-4/h1H2,(H4,9,10,11,12,13) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported no data with Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is a metabolite of the substance 6-(2,2,2-Trifluoroethoxy)-1,3,5-triazine-2,4-diamine 6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine Not in list C5H6F3N5O FC(F)(F)COc1nc(N)nc(N)n1 InChI=1/C5H6F3N5O/c6-5(7,8)1-14-4-12-2(9)11-3(10)13-4/h1H2,(H4,9,10,11,12,13) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported no data without Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is a metabolite of the substance 7-Methyl-1,2-benzisothiazol-3(2H)-one 1,1-dioxide 7-methyl-1,2-benzothiazol-3(2H)-one 1,1-dioxide Not in list C8H7NO3S Cc1cccc2c1S(=O)(=O)NC2=O InChI=1S/C8H7NO3S/c1-5-3-2-4-6-7(5)13(11,12)9-8(6)10/h2-4H,1H3,(H,9,10) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is a metabolite of the substance 7-Methyl-1,2-benzisothiazol-3(2H)-one 1,1-dioxide 7-methyl-1,2-benzothiazol-3(2H)-one 1,1-dioxide Not in list C8H7NO3S Cc1cccc2c1S(=O)(=O)NC2=O InChI=1S/C8H7NO3S/c1-5-3-2-4-6-7(5)13(11,12)9-8(6)10/h2-4H,1H3,(H,9,10) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is a metabolite of the substance 7-Methyl-1,2-benzisothiazol-3(2H)-one 1,1-dioxide 7-methyl-1,2-benzothiazol-3(2H)-one 1,1-dioxide Not in list C8H7NO3S Cc1cccc2c1S(=O)(=O)NC2=O InChI=1S/C8H7NO3S/c1-5-3-2-4-6-7(5)13(11,12)9-8(6)10/h2-4H,1H3,(H,9,10) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is a metabolite of the substance 7-Methyl-1,2-benzisothiazol-3(2H)-one 1,1-dioxide 7-methyl-1,2-benzothiazol-3(2H)-one 1,1-dioxide Not in list C8H7NO3S Cc1cccc2c1S(=O)(=O)NC2=O InChI=1S/C8H7NO3S/c1-5-3-2-4-6-7(5)13(11,12)9-8(6)10/h2-4H,1H3,(H,9,10) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is a metabolite of the substance 7-Methyl-1,2-benzisothiazol-3(2H)-one 1,1-dioxide 7-methyl-1,2-benzothiazol-3(2H)-one 1,1-dioxide Not in list C8H7NO3S Cc1cccc2c1S(=O)(=O)NC2=O InChI=1S/C8H7NO3S/c1-5-3-2-4-6-7(5)13(11,12)9-8(6)10/h2-4H,1H3,(H,9,10) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is a metabolite of the substance 7-Methyl-1,2-benzisothiazol-3(2H)-one 1,1-dioxide 7-methyl-1,2-benzothiazol-3(2H)-one 1,1-dioxide Not in list C8H7NO3S Cc1cccc2c1S(=O)(=O)NC2=O InChI=1S/C8H7NO3S/c1-5-3-2-4-6-7(5)13(11,12)9-8(6)10/h2-4H,1H3,(H,9,10) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is a metabolite of the substance 7-Methyl-1,2-benzisothiazol-3(2H)-one 1,1-dioxide 7-methyl-1,2-benzothiazol-3(2H)-one 1,1-dioxide Not in list C8H7NO3S Cc1cccc2c1S(=O)(=O)NC2=O InChI=1S/C8H7NO3S/c1-5-3-2-4-6-7(5)13(11,12)9-8(6)10/h2-4H,1H3,(H,9,10) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is a metabolite of the substance 7-Methyl-1,2-benzisothiazol-3(2H)-one 1,1-dioxide 7-methyl-1,2-benzothiazol-3(2H)-one 1,1-dioxide Not in list C8H7NO3S Cc1cccc2c1S(=O)(=O)NC2=O InChI=1S/C8H7NO3S/c1-5-3-2-4-6-7(5)13(11,12)9-8(6)10/h2-4H,1H3,(H,9,10) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is a metabolite of the substance 7-Methyl-1,2-benzisothiazol-3(2H)-one 1,1-dioxide 7-methyl-1,2-benzothiazol-3(2H)-one 1,1-dioxide Not in list C8H7NO3S Cc1cccc2c1S(=O)(=O)NC2=O InChI=1S/C8H7NO3S/c1-5-3-2-4-6-7(5)13(11,12)9-8(6)10/h2-4H,1H3,(H,9,10) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is a metabolite of the substance 7-Methyl-1,2-benzisothiazol-3(2H)-one 1,1-dioxide 7-methyl-1,2-benzothiazol-3(2H)-one 1,1-dioxide Not in list C8H7NO3S Cc1cccc2c1S(=O)(=O)NC2=O InChI=1S/C8H7NO3S/c1-5-3-2-4-6-7(5)13(11,12)9-8(6)10/h2-4H,1H3,(H,9,10) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is a metabolite of the substance 7-Methyl-1,2-benzisothiazol-3(2H)-one 1,1-dioxide 7-methyl-1,2-benzothiazol-3(2H)-one 1,1-dioxide Not in list C8H7NO3S Cc1cccc2c1S(=O)(=O)NC2=O InChI=1S/C8H7NO3S/c1-5-3-2-4-6-7(5)13(11,12)9-8(6)10/h2-4H,1H3,(H,9,10) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes without Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is a metabolite of the substance 7-Methyl-1,2-benzisothiazol-3(2H)-one 1,1-dioxide 7-methyl-1,2-benzothiazol-3(2H)-one 1,1-dioxide Not in list C8H7NO3S Cc1cccc2c1S(=O)(=O)NC2=O InChI=1S/C8H7NO3S/c1-5-3-2-4-6-7(5)13(11,12)9-8(6)10/h2-4H,1H3,(H,9,10) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable Hamster (as animal) CHO Not reported yes with Negative RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is a metabolite of the substance 7-Methyl-1,2-benzisothiazol-3(2H)-one 1,1-dioxide 7-methyl-1,2-benzothiazol-3(2H)-one 1,1-dioxide Not in list C8H7NO3S Cc1cccc2c1S(=O)(=O)NC2=O InChI=1S/C8H7NO3S/c1-5-3-2-4-6-7(5)13(11,12)9-8(6)10/h2-4H,1H3,(H,9,10) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: unspecified 48.0000000000 h yes not applicable Negative no evidence RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Triflusulfuron-methyl 126535-15-7 single chemical entity Component is a metabolite of the substance 7-Methyl-1,2-benzisothiazol-3(2H)-one 1,1-dioxide 7-methyl-1,2-benzothiazol-3(2H)-one 1,1-dioxide Not in list C8H7NO3S Cc1cccc2c1S(=O)(=O)NC2=O InChI=1S/C8H7NO3S/c1-5-3-2-4-6-7(5)13(11,12)9-8(6)10/h2-4H,1H3,(H,9,10) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: unspecified 24.0000000000 h yes not applicable Negative no evidence RMS: France Triflusulfuron-methyl 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl). 17Apr2009 2009 doi:10.2903/j.efsa.2009.195r
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Germany Glyphosate 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Germany Glyphosate 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Germany Glyphosate 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Germany Glyphosate 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Germany Glyphosate 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Germany Glyphosate 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Germany Glyphosate 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Germany Glyphosate 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Germany Glyphosate 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported no data without Negative RMS: Germany Glyphosate 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Germany Glyphosate 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Germany Glyphosate 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Germany Glyphosate 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Germany Glyphosate 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Germany Glyphosate 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported no data with Negative RMS: Germany Glyphosate 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Germany Glyphosate 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Germany Glyphosate 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data with Negative large colonies RMS: Germany Glyphosate 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data with Negative small colonies RMS: Germany Glyphosate 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data without Negative large colonies RMS: Germany Glyphosate 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data without Negative small colonies RMS: Germany Glyphosate 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported no data with Negative RMS: Germany Glyphosate 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported no data without Negative RMS: Germany Glyphosate 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro Equivalent or similar to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Yes Acceptable Rat (as animal) hepatocytes Not reported no data without Negative RMS: Germany Glyphosate 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported no data without Negative RMS: Germany Glyphosate 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported no data with Negative RMS: Germany Glyphosate 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Swiss 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Germany Glyphosate 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Swiss 10 Male/Female oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Inconclusive no evidence RMS: Germany Glyphosate 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI No data oral: unspecified 48.0000000000 h no data not applicable Negative RMS: Germany Glyphosate 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI No data oral: unspecified 24.0000000000 h no data not applicable Negative RMS: Germany Glyphosate 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI No data oral: unspecified 72.0000000000 h no data not applicable Negative RMS: Germany Glyphosate 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable Rat (as animal) Sprague-Dawley No data intraperitoneal 24.0000000000 h no data not applicable Negative RMS: Germany Glyphosate 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable Rat (as animal) Sprague-Dawley No data intraperitoneal 12.0000000000 h no data not applicable Negative RMS: Germany Glyphosate 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable Rat (as animal) Sprague-Dawley No data intraperitoneal 6.0000000000 h no data not applicable Negative RMS: Germany Glyphosate 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration dominant lethal assay in vivo According to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) No Acceptable Rat (as animal) Wistar 30 Male oral: gavage 1.0000000000 week yes, concurrent vehicle not applicable Negative RMS: Germany Glyphosate 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration dominant lethal assay in vivo According to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) No Acceptable House mouse (as animal) CD-1 Male oral: unspecified 8.0000000000 week no data not applicable Negative RMS: Germany Glyphosate 1998 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative small colonies RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative small colonies RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative large colonies RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro Equivalent or similar to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) Yes Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative large colonies RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro Equivalent or similar to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) Yes Acceptable Human (as organism) lymphocytes Not reported yes with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 77 Male intraperitoneal 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 7 Male intraperitoneal 48.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Swiss 10 Male/Female intraperitoneal 24.0000000000 h yes not applicable Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female oral: unspecified 48.0000000000 h yes not applicable Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 10 Male/Female oral: unspecified 24.0000000000 h yes not applicable Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 12 Male oral: unspecified 24.0000000000 h yes not applicable Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI 12 Male oral: unspecified 48.0000000000 h yes not applicable Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable Rat (as animal) Crj:CD(SD) 10 Male/Female oral: unspecified 24.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable Rat (as animal) Crj:CD(SD) 10 Male/Female oral: unspecified 48.0000000000 h yes, concurrent vehicle not applicable Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is a metabolite of the substance (aminomethyl)phosphonic acid 623-325-5 1066-51-9 aminomethylphosphonic acid Not in list CH6NO3P C(N)P(=O)(O)O InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is a metabolite of the substance (aminomethyl)phosphonic acid 623-325-5 1066-51-9 aminomethylphosphonic acid Not in list CH6NO3P C(N)P(=O)(O)O InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is a metabolite of the substance (aminomethyl)phosphonic acid 623-325-5 1066-51-9 aminomethylphosphonic acid Not in list CH6NO3P C(N)P(=O)(O)O InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is a metabolite of the substance (aminomethyl)phosphonic acid 623-325-5 1066-51-9 aminomethylphosphonic acid Not in list CH6NO3P C(N)P(=O)(O)O InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is a metabolite of the substance (aminomethyl)phosphonic acid 623-325-5 1066-51-9 aminomethylphosphonic acid Not in list CH6NO3P C(N)P(=O)(O)O InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is a metabolite of the substance (aminomethyl)phosphonic acid 623-325-5 1066-51-9 aminomethylphosphonic acid Not in list CH6NO3P C(N)P(=O)(O)O InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is a metabolite of the substance (aminomethyl)phosphonic acid 623-325-5 1066-51-9 aminomethylphosphonic acid Not in list CH6NO3P C(N)P(=O)(O)O InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is a metabolite of the substance (aminomethyl)phosphonic acid 623-325-5 1066-51-9 aminomethylphosphonic acid Not in list CH6NO3P C(N)P(=O)(O)O InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is a metabolite of the substance (aminomethyl)phosphonic acid 623-325-5 1066-51-9 aminomethylphosphonic acid Not in list CH6NO3P C(N)P(=O)(O)O InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data with Negative no information RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is a metabolite of the substance (aminomethyl)phosphonic acid 623-325-5 1066-51-9 aminomethylphosphonic acid Not in list CH6NO3P C(N)P(=O)(O)O InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data without Negative no information RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is a metabolite of the substance (aminomethyl)phosphonic acid 623-325-5 1066-51-9 aminomethylphosphonic acid Not in list CH6NO3P C(N)P(=O)(O)O InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is a metabolite of the substance (aminomethyl)phosphonic acid 623-325-5 1066-51-9 aminomethylphosphonic acid Not in list CH6NO3P C(N)P(=O)(O)O InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is a metabolite of the substance (aminomethyl)phosphonic acid 623-325-5 1066-51-9 aminomethylphosphonic acid Not in list CH6NO3P C(N)P(=O)(O)O InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is a metabolite of the substance (aminomethyl)phosphonic acid 623-325-5 1066-51-9 aminomethylphosphonic acid Not in list CH6NO3P C(N)P(=O)(O)O InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is a metabolite of the substance (aminomethyl)phosphonic acid 623-325-5 1066-51-9 aminomethylphosphonic acid Not in list CH6NO3P C(N)P(=O)(O)O InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is a metabolite of the substance (aminomethyl)phosphonic acid 623-325-5 1066-51-9 aminomethylphosphonic acid Not in list CH6NO3P C(N)P(=O)(O)O InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is a metabolite of the substance (aminomethyl)phosphonic acid 623-325-5 1066-51-9 aminomethylphosphonic acid Not in list CH6NO3P C(N)P(=O)(O)O InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is a metabolite of the substance (aminomethyl)phosphonic acid 623-325-5 1066-51-9 aminomethylphosphonic acid Not in list CH6NO3P C(N)P(=O)(O)O InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is a metabolite of the substance (aminomethyl)phosphonic acid 623-325-5 1066-51-9 aminomethylphosphonic acid Not in list CH6NO3P C(N)P(=O)(O)O InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is a metabolite of the substance (aminomethyl)phosphonic acid 623-325-5 1066-51-9 aminomethylphosphonic acid Not in list CH6NO3P C(N)P(=O)(O)O InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is a metabolite of the substance (aminomethyl)phosphonic acid 623-325-5 1066-51-9 aminomethylphosphonic acid Not in list CH6NO3P C(N)P(=O)(O)O InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is a metabolite of the substance (aminomethyl)phosphonic acid 623-325-5 1066-51-9 aminomethylphosphonic acid Not in list CH6NO3P C(N)P(=O)(O)O InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is a metabolite of the substance (aminomethyl)phosphonic acid 623-325-5 1066-51-9 aminomethylphosphonic acid Not in list CH6NO3P C(N)P(=O)(O)O InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is a metabolite of the substance (aminomethyl)phosphonic acid 623-325-5 1066-51-9 aminomethylphosphonic acid Not in list CH6NO3P C(N)P(=O)(O)O InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is a metabolite of the substance (aminomethyl)phosphonic acid 623-325-5 1066-51-9 aminomethylphosphonic acid Not in list CH6NO3P C(N)P(=O)(O)O InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is a metabolite of the substance (aminomethyl)phosphonic acid 623-325-5 1066-51-9 aminomethylphosphonic acid Not in list CH6NO3P C(N)P(=O)(O)O InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is a metabolite of the substance (aminomethyl)phosphonic acid 623-325-5 1066-51-9 aminomethylphosphonic acid Not in list CH6NO3P C(N)P(=O)(O)O InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is a metabolite of the substance (aminomethyl)phosphonic acid 623-325-5 1066-51-9 aminomethylphosphonic acid Not in list CH6NO3P C(N)P(=O)(O)O InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is a metabolite of the substance (aminomethyl)phosphonic acid 623-325-5 1066-51-9 aminomethylphosphonic acid Not in list CH6NO3P C(N)P(=O)(O)O InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is a metabolite of the substance (aminomethyl)phosphonic acid 623-325-5 1066-51-9 aminomethylphosphonic acid Not in list CH6NO3P C(N)P(=O)(O)O InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is a metabolite of the substance (aminomethyl)phosphonic acid 623-325-5 1066-51-9 aminomethylphosphonic acid Not in list CH6NO3P C(N)P(=O)(O)O InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is a metabolite of the substance (aminomethyl)phosphonic acid 623-325-5 1066-51-9 aminomethylphosphonic acid Not in list CH6NO3P C(N)P(=O)(O)O InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is a metabolite of the substance (aminomethyl)phosphonic acid 623-325-5 1066-51-9 aminomethylphosphonic acid Not in list CH6NO3P C(N)P(=O)(O)O InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported no data without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is a metabolite of the substance (aminomethyl)phosphonic acid 623-325-5 1066-51-9 aminomethylphosphonic acid Not in list CH6NO3P C(N)P(=O)(O)O InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported no data without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is a metabolite of the substance (aminomethyl)phosphonic acid 623-325-5 1066-51-9 aminomethylphosphonic acid Not in list CH6NO3P C(N)P(=O)(O)O InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) NMRI Male/Female oral: unspecified 24.0000000000 h no data not applicable Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is a metabolite of the substance (aminomethyl)phosphonic acid 623-325-5 1066-51-9 aminomethylphosphonic acid Not in list CH6NO3P C(N)P(=O)(O)O InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 Male/Female intraperitoneal 24.0000000000 h no data not applicable Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (Rodeo) Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (Rodeo) Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (Rodeo) Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (Rodeo) Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (Rodeo) Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (Rodeo) Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (Rodeo) Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (Rodeo) Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (MON 2139) Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (MON 2139) Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (MON 2139) Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (MON 2139) Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (MON 2139) Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (MON 2139) Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (MON 2139) Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (MON 2139) Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (MON 14445t) Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (MON 14445t) Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (MON 14445t) Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported no data without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (MON 14445t) Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (MON 14445t) Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (MON 14445t) Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (MON 14445t) Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (MON 14445t) Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported no data with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (Glifos) Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (Glifos) Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (Glifos) Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (Glifos) Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (Glifos) Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (Glifos) Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported no data with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (Glifos) Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 97 Not reported no data without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (Glifos) Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (Rodeo) Not in list organic no structure chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 Male/Female intraperitoneal 48.0000000000 h no data not applicable Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (Rodeo) Not in list organic no structure chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 Male/Female intraperitoneal 72.0000000000 h no data not applicable Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (Rodeo) Not in list organic no structure chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 Male/Female intraperitoneal 24.0000000000 h no data not applicable Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (Roundup) Not in list organic no structure chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 Male/Female intraperitoneal 72.0000000000 h no data not applicable Negative direct evidence-cytotoxicity RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (Roundup) Not in list organic no structure chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 Male/Female intraperitoneal 48.0000000000 h no data not applicable Negative direct evidence-cytotoxicity RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (Roundup) Not in list organic no structure chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 Male/Female intraperitoneal 24.0000000000 h no data not applicable Negative direct evidence-cytotoxicity RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (MON 14445t) Not in list organic no structure chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 Male/Female intraperitoneal 72.0000000000 h no data not applicable Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (MON 14445t) Not in list organic no structure chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 Male/Female intraperitoneal 24.0000000000 h no data not applicable Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (MON 14445t) Not in list organic no structure chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 Male/Female intraperitoneal 48.0000000000 h no data not applicable Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (Glifos) Not in list organic no structure chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Swiss Male/Female intraperitoneal 24.0000000000 h no data not applicable Negative no evidence RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is part of a group assessment MON 8080 Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is part of a group assessment MON 8080 Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is part of a group assessment MON 8080 Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is part of a group assessment MON 8080 Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is part of a group assessment MON 8080 Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is part of a group assessment MON 8080 Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is part of a group assessment MON 8080 Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is part of a group assessment MON 8080 Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is part of a group assessment MON 0818 Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is part of a group assessment MON 0818 Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is part of a group assessment MON 0818 Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is part of a group assessment MON 0818 Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is part of a group assessment MON 0818 Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is part of a group assessment MON 0818 Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is part of a group assessment MON 0818 Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is part of a group assessment MON 0818 Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is part of a group assessment Dodigen 4022 Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is part of a group assessment Dodigen 4022 Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is part of a group assessment Dodigen 4022 Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is part of a group assessment Dodigen 4022 Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is part of a group assessment Dodigen 4022 Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is part of a group assessment Dodigen 4022 Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported no data without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is part of a group assessment Dodigen 4022 Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is part of a group assessment Dodigen 4022 Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is part of a group assessment Dodigen 4022 Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is part of a group assessment Dodigen 4022 Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is part of a group assessment Dodigen 4022 Not in list organic no structure chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is part of a group assessment Dodigen 4022 Not in list organic no structure chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported no data without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is part of a group assessment MON 0818 Not in list organic no structure chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 Male/Female intraperitoneal 24.0000000000 h no data not applicable Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is part of a group assessment MON 0818 Not in list organic no structure chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) CD-1 Male/Female intraperitoneal 48.0000000000 h no data not applicable Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (Roundup) Not in list organic no structure chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Not reported No data intraperitoneal 24.0000000000 h no data not applicable Negative direct evidence-cytotoxicity RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (Roundup) Not in list organic no structure chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Not reported No data intraperitoneal 48.0000000000 h no data not applicable Negative direct evidence-cytotoxicity RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is part of a group assessment Glyphosate isopropyl amine salt 254-056-8 38641-94-0 N-(phosphonomethyl)glycine - isopropylamine (1:1) Not in list C6H17N2O5P CC(C)[NH3+].CC(C)[NH3+].CC(C)[NH3+].C(C(=O)[O-])NCP(=O)([O-])[O-] InChI=1S/C3H8NO5P.3C3H9N/c5-3(6)1-4-2-10(7,8)9;3*1-3(2)4/h4H,1-2H2,(H,5,6)(H2,7,8,9);3*3H,4H2,1-2H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Not reported No data intraperitoneal 24.0000000000 h no data not applicable Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is part of a group assessment Glyphosate isopropyl amine salt 254-056-8 38641-94-0 N-(phosphonomethyl)glycine - isopropylamine (1:1) Not in list C6H17N2O5P CC(C)[NH3+].CC(C)[NH3+].CC(C)[NH3+].C(C(=O)[O-])NCP(=O)([O-])[O-] InChI=1S/C3H8NO5P.3C3H9N/c5-3(6)1-4-2-10(7,8)9;3*1-3(2)4/h4H,1-2H2,(H,5,6)(H2,7,8,9);3*3H,4H2,1-2H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Not reported No data intraperitoneal 48.0000000000 h no data not applicable Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo Equivalent or similar to OECD Guideline 489 Yes Acceptable House mouse (as animal) Not reported No data intraperitoneal 24.0000000000 h no data not applicable Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (Roundup) Not in list organic no structure DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo Equivalent or similar to OECD Guideline 489 Yes Acceptable House mouse (as animal) Not reported No data intraperitoneal 24.0000000000 h no data not applicable Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo Equivalent or similar to OECD Guideline 489 Yes Acceptable House mouse (as animal) Not reported No data intraperitoneal 4.0000000000 h no data not applicable Positive RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (Roundup) Not in list organic no structure DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo Equivalent or similar to OECD Guideline 489 Yes Acceptable House mouse (as animal) Not reported No data intraperitoneal 4.0000000000 h no data not applicable Positive RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (Roundup) Not in list organic no structure DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo Equivalent or similar to OECD Guideline 489 Yes Acceptable House mouse (as animal) Not reported No data intraperitoneal 24.0000000000 h no data not applicable Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo Equivalent or similar to OECD Guideline 489 Yes Acceptable House mouse (as animal) Not reported No data intraperitoneal 24.0000000000 h no data not applicable Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Swiss No data intraperitoneal 6.0000000000 h no data not applicable Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo Equivalent or similar to OECD Guideline 489 Yes Acceptable House mouse (as animal) Not reported No data intraperitoneal 4.0000000000 h no data not applicable Positive RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (Roundup) Not in list organic no structure chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Swiss No data intraperitoneal 24.0000000000 h no data not applicable Positive RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (Roundup) Not in list organic no structure chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Swiss No data intraperitoneal 6.0000000000 h no data not applicable Positive RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (Roundup) Not in list organic no structure DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo Equivalent or similar to OECD Guideline 489 Yes Acceptable House mouse (as animal) Not reported No data intraperitoneal 4.0000000000 h no data not applicable Positive RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Swiss No data intraperitoneal 24.0000000000 h no data not applicable Positive RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (Roundup) Not in list organic no structure DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) hepatocytes intraperitoneal no data not applicable Ambiguous RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is part of a group assessment Glyphosate isopropyl amine salt 254-056-8 38641-94-0 N-(phosphonomethyl)glycine - isopropylamine (1:1) Not in list C6H17N2O5P CC(C)[NH3+].CC(C)[NH3+].CC(C)[NH3+].C(C(=O)[O-])NCP(=O)([O-])[O-] InChI=1S/C3H8NO5P.3C3H9N/c5-3(6)1-4-2-10(7,8)9;3*1-3(2)4/h4H,1-2H2,(H,5,6)(H2,7,8,9);3*3H,4H2,1-2H3 organic compound Other Other DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) kidney cells intraperitoneal no data not applicable Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is part of a group assessment Glyphosate isopropyl amine salt 254-056-8 38641-94-0 N-(phosphonomethyl)glycine - isopropylamine (1:1) Not in list C6H17N2O5P CC(C)[NH3+].CC(C)[NH3+].CC(C)[NH3+].C(C(=O)[O-])NCP(=O)([O-])[O-] InChI=1S/C3H8NO5P.3C3H9N/c5-3(6)1-4-2-10(7,8)9;3*1-3(2)4/h4H,1-2H2,(H,5,6)(H2,7,8,9);3*3H,4H2,1-2H3 organic compound Other Other DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) hepatocytes intraperitoneal no data not applicable Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (Roundup) Not in list organic no structure DNA damage and/or repair other in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) kidney cells intraperitoneal no data not applicable Ambiguous RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (Roundup) Not in list organic no structure DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vivo Equivalent or similar to OECD Guideline 489 No data Acceptable Other Not reported No data Not reported 24.0000000000 h no data not applicable Positive RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (Roundup) Not in list organic no structure chromosome aberration dominant lethal assay in vivo No guideline available Not reported Not applicable Acceptable Drosophila melanogaster (as animal) Not reported Male oral: feed no data not applicable Positive RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro According to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No Acceptable Human (as organism) lymphocytes Not reported no data no data Positive RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro According to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No Acceptable Bovinae (bovines = Tribe bovini) (as animal) lymphocytes Not reported no data no data Positive RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Bovinae (bovines = Tribe bovini) (as animal) lymphocytes Not reported no data no data Positive RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported no data no data Positive RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Not reported No data intraperitoneal 72.0000000000 h no data not applicable Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (Percozyd 10 SL) Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data no data Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Not reported No data intraperitoneal 48.0000000000 h no data not applicable Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Not reported No data intraperitoneal 24.0000000000 h no data not applicable Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (Percozyd 10 SL) Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data no data Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (Percozyd 10 SL) Not in list organic no structure gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data no data Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI gene mutation other in vitro No guideline available Not reported Not applicable Acceptable Drosophila melanogaster (as animal) Not reported Not reported no data no data Inconclusive RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is part of a group assessment Glyphosate isopropyl amine salt 254-056-8 38641-94-0 N-(phosphonomethyl)glycine - isopropylamine (1:1) Not in list C6H17N2O5P CC(C)[NH3+].CC(C)[NH3+].CC(C)[NH3+].C(C(=O)[O-])NCP(=O)([O-])[O-] InChI=1S/C3H8NO5P.3C3H9N/c5-3(6)1-4-2-10(7,8)9;3*1-3(2)4/h4H,1-2H2,(H,5,6)(H2,7,8,9);3*3H,4H2,1-2H3 organic compound Other Other chromosome aberration in vitro mammalian cell micronucleus test in vitro According to OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test) No Acceptable Bovinae (bovines = Tribe bovini) (as animal) lymphocytes Not reported no data without Positive RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is part of a group assessment Glyphosate isopropyl amine salt 254-056-8 38641-94-0 N-(phosphonomethyl)glycine - isopropylamine (1:1) Not in list C6H17N2O5P CC(C)[NH3+].CC(C)[NH3+].CC(C)[NH3+].C(C(=O)[O-])NCP(=O)([O-])[O-] InChI=1S/C3H8NO5P.3C3H9N/c5-3(6)1-4-2-10(7,8)9;3*1-3(2)4/h4H,1-2H2,(H,5,6)(H2,7,8,9);3*3H,4H2,1-2H3 organic compound Other Other chromosome aberration in vitro mammalian cell micronucleus test in vitro According to OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test) No Acceptable Bovinae (bovines = Tribe bovini) (as animal) lymphocytes Not reported no data with Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is part of a group assessment Glyphosate isopropyl amine salt 254-056-8 38641-94-0 N-(phosphonomethyl)glycine - isopropylamine (1:1) Not in list C6H17N2O5P CC(C)[NH3+].CC(C)[NH3+].CC(C)[NH3+].C(C(=O)[O-])NCP(=O)([O-])[O-] InChI=1S/C3H8NO5P.3C3H9N/c5-3(6)1-4-2-10(7,8)9;3*1-3(2)4/h4H,1-2H2,(H,5,6)(H2,7,8,9);3*3H,4H2,1-2H3 organic compound Other Other chromosome aberration in vitro mammalian cell micronucleus test in vitro According to OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test) No Acceptable Bovinae (bovines = Tribe bovini) (as animal) lymphocytes Not reported no data without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is part of a group assessment Glyphosate isopropyl amine salt 254-056-8 38641-94-0 N-(phosphonomethyl)glycine - isopropylamine (1:1) Not in list C6H17N2O5P CC(C)[NH3+].CC(C)[NH3+].CC(C)[NH3+].C(C(=O)[O-])NCP(=O)([O-])[O-] InChI=1S/C3H8NO5P.3C3H9N/c5-3(6)1-4-2-10(7,8)9;3*1-3(2)4/h4H,1-2H2,(H,5,6)(H2,7,8,9);3*3H,4H2,1-2H3 organic compound Other Other chromosome aberration in vitro mammalian cell micronucleus test in vitro According to OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test) No Acceptable Bovinae (bovines = Tribe bovini) (as animal) lymphocytes Not reported no data without Positive RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (Herbazed) Not in list organic no structure chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable House mouse (as animal) Not reported No data intraperitoneal 1.0000000000 D no data not applicable Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (Herbazed) Not in list organic no structure chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable House mouse (as animal) spleen cells Not reported no data without Positive RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (Herbazed) Not in list organic no structure DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro According to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No Acceptable House mouse (as animal) spleen cells Not reported no data without Positive RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (Herbazed) Not in list organic no structure chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable House mouse (as animal) Not reported No data oral: unspecified 21.0000000000 D no data not applicable Positive RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (Herbazed) Not in list organic no structure chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable House mouse (as animal) Not reported No data oral: unspecified 14.0000000000 D no data not applicable Positive RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (Herbazed) Not in list organic no structure chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable House mouse (as animal) Not reported No data oral: unspecified 7.0000000000 D no data not applicable Positive RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (Herbazed) Not in list organic no structure chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable House mouse (as animal) Not reported No data oral: unspecified 1.0000000000 D no data not applicable Positive RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (Herbazed) Not in list organic no structure chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable House mouse (as animal) Not reported No data intraperitoneal 3.0000000000 D no data not applicable Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (Herbazed) Not in list organic no structure chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable House mouse (as animal) Not reported No data intraperitoneal 5.0000000000 D no data not applicable Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is part of a group assessment Glyphosate isopropyl amine salt 254-056-8 38641-94-0 N-(phosphonomethyl)glycine - isopropylamine (1:1) Not in list C6H17N2O5P CC(C)[NH3+].CC(C)[NH3+].CC(C)[NH3+].C(C(=O)[O-])NCP(=O)([O-])[O-] InChI=1S/C3H8NO5P.3C3H9N/c5-3(6)1-4-2-10(7,8)9;3*1-3(2)4/h4H,1-2H2,(H,5,6)(H2,7,8,9);3*3H,4H2,1-2H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Bovinae (bovines = Tribe bovini) (as animal) lymphocytes Not reported no without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is part of a group assessment Glyphosate isopropyl amine salt 254-056-8 38641-94-0 N-(phosphonomethyl)glycine - isopropylamine (1:1) Not in list C6H17N2O5P CC(C)[NH3+].CC(C)[NH3+].CC(C)[NH3+].C(C(=O)[O-])NCP(=O)([O-])[O-] InChI=1S/C3H8NO5P.3C3H9N/c5-3(6)1-4-2-10(7,8)9;3*1-3(2)4/h4H,1-2H2,(H,5,6)(H2,7,8,9);3*3H,4H2,1-2H3 organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Bovinae (bovines = Tribe bovini) (as animal) lymphocytes Not reported no data without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is part of a group assessment Glyphosate isopropyl amine salt 254-056-8 38641-94-0 N-(phosphonomethyl)glycine - isopropylamine (1:1) Not in list C6H17N2O5P CC(C)[NH3+].CC(C)[NH3+].CC(C)[NH3+].C(C(=O)[O-])NCP(=O)([O-])[O-] InChI=1S/C3H8NO5P.3C3H9N/c5-3(6)1-4-2-10(7,8)9;3*1-3(2)4/h4H,1-2H2,(H,5,6)(H2,7,8,9);3*3H,4H2,1-2H3 organic compound Other Other DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro According to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No Acceptable Bovinae (bovines = Tribe bovini) (as animal) lymphocytes Not reported no data no data Positive RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported no data without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair single cell gel/comet assay in mammalian cells for detection of DNA damage in vitro No guideline available Not reported Not applicable Acceptable Human (as organism) Not reported Not reported no data without Positive RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Not reported No data intraperitoneal no data not applicable Positive RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian cell micronucleus test in vitro According to OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test) No Acceptable Human (as organism) lymphocytes Not reported no data with Positive RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro According to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No Acceptable Human (as organism) lymphocytes Not reported no data without Positive RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro According to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No Acceptable Human (as organism) lymphocytes Not reported no data with Positive RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian cell micronucleus test in vitro According to OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test) No Acceptable Human (as organism) lymphocytes Not reported no data without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian cell micronucleus test in vitro According to OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test) No Acceptable Human (as organism) lymphocytes Not reported no data without Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian cell micronucleus test in vitro According to OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test) No Acceptable Human (as organism) lymphocytes Not reported no data with Positive RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (Roundup) Not in list organic no structure chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Not reported No data intraperitoneal no data not applicable Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (Roundup) Not in list organic no structure chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Not reported No data intraperitoneal no data not applicable Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (Roundup) Not in list organic no structure chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable Rabbit (as animal) Not reported No data oral: feed 60.0000000000 D no data not applicable Positive RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (Roundup) Not in list organic no structure chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable House mouse (as animal) Not reported No data oral: unspecified no data not applicable Negative RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is the active ingredient of the mixture or formulation Glyphosate formulation (Roundup) Not in list organic no structure chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable House mouse (as animal) Not reported No data intraperitoneal no data not applicable Positive RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Glyphosate 213-997-4 1071-83-6 single chemical entity Component is identical to the substance Glyphosate 213-997-4 1071-83-6 2-(phosphonomethylamino)acetic acid Glyphosate C3H8NO5P C(C(=O)O)NCP(=O)(O)O InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair sister chromatid exchange assay in mammalian cells in vitro According to OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells) No Acceptable Human (as organism) fibroblast Not reported no data without Positive RMS: Germany - CoRMS: Slovakia Glyphosate (Renewal Assessment Report) 2013 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate 30Oct2015 2015 doi:10.2903/j.efsa.2015.4302
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is identical to the substance Tolylfluanid 211-986-9 731-27-1 N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline Tolylfluanid C10H13Cl2FN2O2S2 CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable House mouse (as animal) NMRI 5 Male intraperitoneal 12.0000000000 h yes not applicable Negative RMS: Finland Tolylfluanid (Final addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is identical to the substance Tolylfluanid 211-986-9 731-27-1 N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline Tolylfluanid C10H13Cl2FN2O2S2 CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable House mouse (as animal) NMRI 5 Male intraperitoneal 48.0000000000 h yes not applicable Negative RMS: Finland Tolylfluanid (Final addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Tolylfluanid 211-986-9 731-27-1 single chemical entity Component is identical to the substance Tolylfluanid 211-986-9 731-27-1 N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline Tolylfluanid C10H13Cl2FN2O2S2 CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable House mouse (as animal) NMRI 5 Male intraperitoneal 24.0000000000 h yes not applicable Negative RMS: Finland Tolylfluanid (Final addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid 21Apr2005 2005 doi:10.2903/j.efsa.2005.29r
+Thiabendazole 205-725-8 148-79-8 single chemical entity Component is identical to the substance Thiabendazole 205-725-8 148-79-8 2-(thiazol-4-yl)benzimidazole Thiabendazole C10H7N3S C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3 InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle without Negative RMS: Spain Thiabendazole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole 04Nov2014 2014 doi:10.2903/j.efsa.2014.3880
+Thiabendazole 205-725-8 148-79-8 single chemical entity Component is identical to the substance Thiabendazole 205-725-8 148-79-8 2-(thiazol-4-yl)benzimidazole Thiabendazole C10H7N3S C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3 InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Spain Thiabendazole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole 04Nov2014 2014 doi:10.2903/j.efsa.2014.3880
+Thiabendazole 205-725-8 148-79-8 single chemical entity Component is identical to the substance Thiabendazole 205-725-8 148-79-8 2-(thiazol-4-yl)benzimidazole Thiabendazole C10H7N3S C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3 InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Spain Thiabendazole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole 04Nov2014 2014 doi:10.2903/j.efsa.2014.3880
+Thiabendazole 205-725-8 148-79-8 single chemical entity Component is identical to the substance Thiabendazole 205-725-8 148-79-8 2-(thiazol-4-yl)benzimidazole Thiabendazole C10H7N3S C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3 InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle without Negative RMS: Spain Thiabendazole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole 04Nov2014 2014 doi:10.2903/j.efsa.2014.3880
+Thiabendazole 205-725-8 148-79-8 single chemical entity Component is identical to the substance Thiabendazole 205-725-8 148-79-8 2-(thiazol-4-yl)benzimidazole Thiabendazole C10H7N3S C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3 InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 97 Not reported yes, concurrent vehicle with Negative RMS: Spain Thiabendazole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole 04Nov2014 2014 doi:10.2903/j.efsa.2014.3880
+Thiabendazole 205-725-8 148-79-8 single chemical entity Component is identical to the substance Thiabendazole 205-725-8 148-79-8 2-(thiazol-4-yl)benzimidazole Thiabendazole C10H7N3S C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3 InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle with Negative RMS: Spain Thiabendazole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole 04Nov2014 2014 doi:10.2903/j.efsa.2014.3880
+Thiabendazole 205-725-8 148-79-8 single chemical entity Component is identical to the substance Thiabendazole 205-725-8 148-79-8 2-(thiazol-4-yl)benzimidazole Thiabendazole C10H7N3S C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3 InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Spain Thiabendazole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole 04Nov2014 2014 doi:10.2903/j.efsa.2014.3880
+Thiabendazole 205-725-8 148-79-8 single chemical entity Component is identical to the substance Thiabendazole 205-725-8 148-79-8 2-(thiazol-4-yl)benzimidazole Thiabendazole C10H7N3S C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3 InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Spain Thiabendazole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole 04Nov2014 2014 doi:10.2903/j.efsa.2014.3880
+Thiabendazole 205-725-8 148-79-8 single chemical entity Component is identical to the substance Thiabendazole 205-725-8 148-79-8 2-(thiazol-4-yl)benzimidazole Thiabendazole C10H7N3S C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3 InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Spain Thiabendazole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole 04Nov2014 2014 doi:10.2903/j.efsa.2014.3880
+Thiabendazole 205-725-8 148-79-8 single chemical entity Component is identical to the substance Thiabendazole 205-725-8 148-79-8 2-(thiazol-4-yl)benzimidazole Thiabendazole C10H7N3S C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3 InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Spain Thiabendazole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole 04Nov2014 2014 doi:10.2903/j.efsa.2014.3880
+Thiabendazole 205-725-8 148-79-8 single chemical entity Component is identical to the substance Thiabendazole 205-725-8 148-79-8 2-(thiazol-4-yl)benzimidazole Thiabendazole C10H7N3S C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3 InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Spain Thiabendazole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole 04Nov2014 2014 doi:10.2903/j.efsa.2014.3880
+Thiabendazole 205-725-8 148-79-8 single chemical entity Component is identical to the substance Thiabendazole 205-725-8 148-79-8 2-(thiazol-4-yl)benzimidazole Thiabendazole C10H7N3S C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3 InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Spain Thiabendazole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole 04Nov2014 2014 doi:10.2903/j.efsa.2014.3880
+Thiabendazole 205-725-8 148-79-8 single chemical entity Component is identical to the substance Thiabendazole 205-725-8 148-79-8 2-(thiazol-4-yl)benzimidazole Thiabendazole C10H7N3S C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3 InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Spain Thiabendazole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole 04Nov2014 2014 doi:10.2903/j.efsa.2014.3880
+Thiabendazole 205-725-8 148-79-8 single chemical entity Component is identical to the substance Thiabendazole 205-725-8 148-79-8 2-(thiazol-4-yl)benzimidazole Thiabendazole C10H7N3S C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3 InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Spain Thiabendazole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole 04Nov2014 2014 doi:10.2903/j.efsa.2014.3880
+Thiabendazole 205-725-8 148-79-8 single chemical entity Component is identical to the substance Thiabendazole 205-725-8 148-79-8 2-(thiazol-4-yl)benzimidazole Thiabendazole C10H7N3S C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3 InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Spain Thiabendazole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole 04Nov2014 2014 doi:10.2903/j.efsa.2014.3880
+Thiabendazole 205-725-8 148-79-8 single chemical entity Component is identical to the substance Thiabendazole 205-725-8 148-79-8 2-(thiazol-4-yl)benzimidazole Thiabendazole C10H7N3S C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3 InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Spain Thiabendazole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole 04Nov2014 2014 doi:10.2903/j.efsa.2014.3880
+Thiabendazole 205-725-8 148-79-8 single chemical entity Component is identical to the substance Thiabendazole 205-725-8 148-79-8 2-(thiazol-4-yl)benzimidazole Thiabendazole C10H7N3S C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3 InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Spain Thiabendazole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole 04Nov2014 2014 doi:10.2903/j.efsa.2014.3880
+Thiabendazole 205-725-8 148-79-8 single chemical entity Component is identical to the substance Thiabendazole 205-725-8 148-79-8 2-(thiazol-4-yl)benzimidazole Thiabendazole C10H7N3S C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3 InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle without Negative RMS: Spain Thiabendazole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole 04Nov2014 2014 doi:10.2903/j.efsa.2014.3880
+Thiabendazole 205-725-8 148-79-8 single chemical entity Component is identical to the substance Thiabendazole 205-725-8 148-79-8 2-(thiazol-4-yl)benzimidazole Thiabendazole C10H7N3S C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3 InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Spain Thiabendazole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole 04Nov2014 2014 doi:10.2903/j.efsa.2014.3880
+Thiabendazole 205-725-8 148-79-8 single chemical entity Component is identical to the substance Thiabendazole 205-725-8 148-79-8 2-(thiazol-4-yl)benzimidazole Thiabendazole C10H7N3S C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3 InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Spain Thiabendazole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole 04Nov2014 2014 doi:10.2903/j.efsa.2014.3880
+Thiabendazole 205-725-8 148-79-8 single chemical entity Component is identical to the substance Thiabendazole 205-725-8 148-79-8 2-(thiazol-4-yl)benzimidazole Thiabendazole C10H7N3S C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3 InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Spain Thiabendazole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole 04Nov2014 2014 doi:10.2903/j.efsa.2014.3880
+Thiabendazole 205-725-8 148-79-8 single chemical entity Component is identical to the substance Thiabendazole 205-725-8 148-79-8 2-(thiazol-4-yl)benzimidazole Thiabendazole C10H7N3S C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3 InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 Not reported yes, concurrent vehicle with Negative RMS: Spain Thiabendazole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole 04Nov2014 2014 doi:10.2903/j.efsa.2014.3880
+Thiabendazole 205-725-8 148-79-8 single chemical entity Component is identical to the substance Thiabendazole 205-725-8 148-79-8 2-(thiazol-4-yl)benzimidazole Thiabendazole C10H7N3S C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3 InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle without Negative RMS: Spain Thiabendazole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole 04Nov2014 2014 doi:10.2903/j.efsa.2014.3880
+Thiabendazole 205-725-8 148-79-8 single chemical entity Component is identical to the substance Thiabendazole 205-725-8 148-79-8 2-(thiazol-4-yl)benzimidazole Thiabendazole C10H7N3S C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3 InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported yes, concurrent vehicle with Negative RMS: Spain Thiabendazole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole 04Nov2014 2014 doi:10.2903/j.efsa.2014.3880
+Thiabendazole 205-725-8 148-79-8 single chemical entity Component is identical to the substance Thiabendazole 205-725-8 148-79-8 2-(thiazol-4-yl)benzimidazole Thiabendazole C10H7N3S C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3 InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration yeast cytogenetic assay in vitro According to OECD Guideline 480 (Genetic Toxicology: Saccharomyces cerevisiae, Gene Mutation Assay) No Acceptable Saccharomyces cerevisiae (as organism) Not reported Not reported no data no data Positive RMS: Spain Thiabendazole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole 04Nov2014 2014 doi:10.2903/j.efsa.2014.3880
+Thiabendazole 205-725-8 148-79-8 single chemical entity Component is identical to the substance Thiabendazole 205-725-8 148-79-8 2-(thiazol-4-yl)benzimidazole Thiabendazole C10H7N3S C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3 InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration yeast cytogenetic assay in vitro According to OECD Guideline 480 (Genetic Toxicology: Saccharomyces cerevisiae, Gene Mutation Assay) No Acceptable Aspergillus nidulans (as organism) Not reported Not reported no data no data Positive RMS: Spain Thiabendazole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole 04Nov2014 2014 doi:10.2903/j.efsa.2014.3880
+Thiabendazole 205-725-8 148-79-8 single chemical entity Component is identical to the substance Thiabendazole 205-725-8 148-79-8 2-(thiazol-4-yl)benzimidazole Thiabendazole C10H7N3S C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3 InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) Not reported Not reported no data no data Positive RMS: Spain Thiabendazole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole 04Nov2014 2014 doi:10.2903/j.efsa.2014.3880
+Thiabendazole 205-725-8 148-79-8 single chemical entity Component is identical to the substance Thiabendazole 205-725-8 148-79-8 2-(thiazol-4-yl)benzimidazole Thiabendazole C10H7N3S C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3 InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) embryo cells Not reported no data without Positive RMS: Spain Thiabendazole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole 04Nov2014 2014 doi:10.2903/j.efsa.2014.3880
+Thiabendazole 205-725-8 148-79-8 single chemical entity Component is identical to the substance Thiabendazole 205-725-8 148-79-8 2-(thiazol-4-yl)benzimidazole Thiabendazole C10H7N3S C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3 InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes, concurrent vehicle without Negative RMS: Spain Thiabendazole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole 04Nov2014 2014 doi:10.2903/j.efsa.2014.3880
+Thiabendazole 205-725-8 148-79-8 single chemical entity Component is identical to the substance Thiabendazole 205-725-8 148-79-8 2-(thiazol-4-yl)benzimidazole Thiabendazole C10H7N3S C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3 InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) M45 Not reported yes, concurrent vehicle with Negative RMS: Spain Thiabendazole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole 04Nov2014 2014 doi:10.2903/j.efsa.2014.3880
+Thiabendazole 205-725-8 148-79-8 single chemical entity Component is identical to the substance Thiabendazole 205-725-8 148-79-8 2-(thiazol-4-yl)benzimidazole Thiabendazole C10H7N3S C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3 InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes, concurrent vehicle without Negative RMS: Spain Thiabendazole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole 04Nov2014 2014 doi:10.2903/j.efsa.2014.3880
+Thiabendazole 205-725-8 148-79-8 single chemical entity Component is identical to the substance Thiabendazole 205-725-8 148-79-8 2-(thiazol-4-yl)benzimidazole Thiabendazole C10H7N3S C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3 InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair Bacillus subtilis recombination assay in vitro No guideline available Not reported Not applicable Acceptable Bacillus subtilis (as organism) H17 Not reported yes, concurrent vehicle with Negative RMS: Spain Thiabendazole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole 04Nov2014 2014 doi:10.2903/j.efsa.2014.3880
+Thiabendazole 205-725-8 148-79-8 single chemical entity Component is identical to the substance Thiabendazole 205-725-8 148-79-8 2-(thiazol-4-yl)benzimidazole Thiabendazole C10H7N3S C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3 InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) Not applicable Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle no data Negative RMS: Spain Thiabendazole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole 04Nov2014 2014 doi:10.2903/j.efsa.2014.3880
+Thiabendazole 205-725-8 148-79-8 single chemical entity Component is identical to the substance Thiabendazole 205-725-8 148-79-8 2-(thiazol-4-yl)benzimidazole Thiabendazole C10H7N3S C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3 InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration chromosome aberration assay in vivo According to OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test) No Acceptable House mouse (as animal) CD-1 Male oral: gavage 24.0000000000 h no data not applicable Negative RMS: Spain Thiabendazole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole 04Nov2014 2014 doi:10.2903/j.efsa.2014.3880
+Thiabendazole 205-725-8 148-79-8 single chemical entity Component is identical to the substance Thiabendazole 205-725-8 148-79-8 2-(thiazol-4-yl)benzimidazole Thiabendazole C10H7N3S C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3 InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation other in vivo No guideline available Not reported Not applicable Acceptable House mouse (as animal) ICR No data intraperitoneal 3.0000000000 h no data not applicable Negative RMS: Spain Thiabendazole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole 04Nov2014 2014 doi:10.2903/j.efsa.2014.3880
+Thiabendazole 205-725-8 148-79-8 single chemical entity Component is identical to the substance Thiabendazole 205-725-8 148-79-8 2-(thiazol-4-yl)benzimidazole Thiabendazole C10H7N3S C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3 InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration dominant lethal assay in vivo According to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) No Acceptable House mouse (as animal) C3H 15 Male oral: unspecified 6.0000000000 week no data not applicable Negative RMS: Spain Thiabendazole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole 04Nov2014 2014 doi:10.2903/j.efsa.2014.3880
+Thiabendazole 205-725-8 148-79-8 single chemical entity Component is identical to the substance Thiabendazole 205-725-8 148-79-8 2-(thiazol-4-yl)benzimidazole Thiabendazole C10H7N3S C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3 InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration dominant lethal assay in vivo According to OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test) No Acceptable House mouse (as animal) CD-1 No data oral: gavage 8.0000000000 week no data not applicable Negative RMS: Spain Thiabendazole 1996 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole 04Nov2014 2014 doi:10.2903/j.efsa.2014.3880
+Flurtamone 619-224-0 96525-23-4 mixture or formulation Component is identical to the substance Flurtamone 619-224-0 96525-23-4 (RS)-5-methylamino-2-phenyl-4-(α,α,α-trifluoro-m-tolyl)furan-3(2H)-one Flurtamone C18H14F3NO2 CNC1=C(C(=O)C(O1)C2=CC=CC=C2)C3=CC(=CC=C3)C(F)(F)F InChI=1S/C18H14F3NO2/c1-22-17-14(12-8-5-9-13(10-12)18(19,20)21)15(23)16(24-17)11-6-3-2-4-7-11/h2-10,16,22H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Czech Republic - CoRMS: Ireland Flurtamone Active substance data 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance flurtamone 06Jun2016 2016 doi: 10.2903/j.efsa.2016.4498
+Flurtamone 619-224-0 96525-23-4 mixture or formulation Component is identical to the substance Flurtamone 619-224-0 96525-23-4 (RS)-5-methylamino-2-phenyl-4-(α,α,α-trifluoro-m-tolyl)furan-3(2H)-one Flurtamone C18H14F3NO2 CNC1=C(C(=O)C(O1)C2=CC=CC=C2)C3=CC(=CC=C3)C(F)(F)F InChI=1S/C18H14F3NO2/c1-22-17-14(12-8-5-9-13(10-12)18(19,20)21)15(23)16(24-17)11-6-3-2-4-7-11/h2-10,16,22H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Czech Republic - CoRMS: Ireland Flurtamone Active substance data 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance flurtamone 06Jun2016 2016 doi: 10.2903/j.efsa.2016.4498
+Flurtamone 619-224-0 96525-23-4 mixture or formulation Component is identical to the substance Flurtamone 619-224-0 96525-23-4 (RS)-5-methylamino-2-phenyl-4-(α,α,α-trifluoro-m-tolyl)furan-3(2H)-one Flurtamone C18H14F3NO2 CNC1=C(C(=O)C(O1)C2=CC=CC=C2)C3=CC(=CC=C3)C(F)(F)F InChI=1S/C18H14F3NO2/c1-22-17-14(12-8-5-9-13(10-12)18(19,20)21)15(23)16(24-17)11-6-3-2-4-7-11/h2-10,16,22H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Czech Republic - CoRMS: Ireland Flurtamone Active substance data 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance flurtamone 06Jun2016 2016 doi: 10.2903/j.efsa.2016.4498
+Flurtamone 619-224-0 96525-23-4 mixture or formulation Component is identical to the substance Flurtamone 619-224-0 96525-23-4 (RS)-5-methylamino-2-phenyl-4-(α,α,α-trifluoro-m-tolyl)furan-3(2H)-one Flurtamone C18H14F3NO2 CNC1=C(C(=O)C(O1)C2=CC=CC=C2)C3=CC(=CC=C3)C(F)(F)F InChI=1S/C18H14F3NO2/c1-22-17-14(12-8-5-9-13(10-12)18(19,20)21)15(23)16(24-17)11-6-3-2-4-7-11/h2-10,16,22H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Czech Republic - CoRMS: Ireland Flurtamone Active substance data 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance flurtamone 06Jun2016 2016 doi: 10.2903/j.efsa.2016.4498
+Flurtamone 619-224-0 96525-23-4 mixture or formulation Component is identical to the substance Flurtamone 619-224-0 96525-23-4 (RS)-5-methylamino-2-phenyl-4-(α,α,α-trifluoro-m-tolyl)furan-3(2H)-one Flurtamone C18H14F3NO2 CNC1=C(C(=O)C(O1)C2=CC=CC=C2)C3=CC(=CC=C3)C(F)(F)F InChI=1S/C18H14F3NO2/c1-22-17-14(12-8-5-9-13(10-12)18(19,20)21)15(23)16(24-17)11-6-3-2-4-7-11/h2-10,16,22H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle without Negative RMS: Czech Republic - CoRMS: Ireland Flurtamone Active substance data 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance flurtamone 06Jun2016 2016 doi: 10.2903/j.efsa.2016.4498
+Flurtamone 619-224-0 96525-23-4 mixture or formulation Component is identical to the substance Flurtamone 619-224-0 96525-23-4 (RS)-5-methylamino-2-phenyl-4-(α,α,α-trifluoro-m-tolyl)furan-3(2H)-one Flurtamone C18H14F3NO2 CNC1=C(C(=O)C(O1)C2=CC=CC=C2)C3=CC(=CC=C3)C(F)(F)F InChI=1S/C18H14F3NO2/c1-22-17-14(12-8-5-9-13(10-12)18(19,20)21)15(23)16(24-17)11-6-3-2-4-7-11/h2-10,16,22H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Czech Republic - CoRMS: Ireland Flurtamone Active substance data 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance flurtamone 06Jun2016 2016 doi: 10.2903/j.efsa.2016.4498
+Flurtamone 619-224-0 96525-23-4 mixture or formulation Component is identical to the substance Flurtamone 619-224-0 96525-23-4 (RS)-5-methylamino-2-phenyl-4-(α,α,α-trifluoro-m-tolyl)furan-3(2H)-one Flurtamone C18H14F3NO2 CNC1=C(C(=O)C(O1)C2=CC=CC=C2)C3=CC(=CC=C3)C(F)(F)F InChI=1S/C18H14F3NO2/c1-22-17-14(12-8-5-9-13(10-12)18(19,20)21)15(23)16(24-17)11-6-3-2-4-7-11/h2-10,16,22H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Czech Republic - CoRMS: Ireland Flurtamone Active substance data 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance flurtamone 06Jun2016 2016 doi: 10.2903/j.efsa.2016.4498
+Flurtamone 619-224-0 96525-23-4 mixture or formulation Component is identical to the substance Flurtamone 619-224-0 96525-23-4 (RS)-5-methylamino-2-phenyl-4-(α,α,α-trifluoro-m-tolyl)furan-3(2H)-one Flurtamone C18H14F3NO2 CNC1=C(C(=O)C(O1)C2=CC=CC=C2)C3=CC(=CC=C3)C(F)(F)F InChI=1S/C18H14F3NO2/c1-22-17-14(12-8-5-9-13(10-12)18(19,20)21)15(23)16(24-17)11-6-3-2-4-7-11/h2-10,16,22H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A Not reported yes, concurrent vehicle with Negative RMS: Czech Republic - CoRMS: Ireland Flurtamone Active substance data 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance flurtamone 06Jun2016 2016 doi: 10.2903/j.efsa.2016.4498
+Flurtamone 619-224-0 96525-23-4 mixture or formulation Component is identical to the substance Flurtamone 619-224-0 96525-23-4 (RS)-5-methylamino-2-phenyl-4-(α,α,α-trifluoro-m-tolyl)furan-3(2H)-one Flurtamone C18H14F3NO2 CNC1=C(C(=O)C(O1)C2=CC=CC=C2)C3=CC(=CC=C3)C(F)(F)F InChI=1S/C18H14F3NO2/c1-22-17-14(12-8-5-9-13(10-12)18(19,20)21)15(23)16(24-17)11-6-3-2-4-7-11/h2-10,16,22H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Czech Republic - CoRMS: Ireland Flurtamone Active substance data 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance flurtamone 06Jun2016 2016 doi: 10.2903/j.efsa.2016.4498
+Flurtamone 619-224-0 96525-23-4 mixture or formulation Component is identical to the substance Flurtamone 619-224-0 96525-23-4 (RS)-5-methylamino-2-phenyl-4-(α,α,α-trifluoro-m-tolyl)furan-3(2H)-one Flurtamone C18H14F3NO2 CNC1=C(C(=O)C(O1)C2=CC=CC=C2)C3=CC(=CC=C3)C(F)(F)F InChI=1S/C18H14F3NO2/c1-22-17-14(12-8-5-9-13(10-12)18(19,20)21)15(23)16(24-17)11-6-3-2-4-7-11/h2-10,16,22H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Czech Republic - CoRMS: Ireland Flurtamone Active substance data 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance flurtamone 06Jun2016 2016 doi: 10.2903/j.efsa.2016.4498
+Flurtamone 619-224-0 96525-23-4 mixture or formulation Component is identical to the substance Flurtamone 619-224-0 96525-23-4 (RS)-5-methylamino-2-phenyl-4-(α,α,α-trifluoro-m-tolyl)furan-3(2H)-one Flurtamone C18H14F3NO2 CNC1=C(C(=O)C(O1)C2=CC=CC=C2)C3=CC(=CC=C3)C(F)(F)F InChI=1S/C18H14F3NO2/c1-22-17-14(12-8-5-9-13(10-12)18(19,20)21)15(23)16(24-17)11-6-3-2-4-7-11/h2-10,16,22H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Czech Republic - CoRMS: Ireland Flurtamone Active substance data 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance flurtamone 06Jun2016 2016 doi: 10.2903/j.efsa.2016.4498
+Flurtamone 619-224-0 96525-23-4 mixture or formulation Component is identical to the substance Flurtamone 619-224-0 96525-23-4 (RS)-5-methylamino-2-phenyl-4-(α,α,α-trifluoro-m-tolyl)furan-3(2H)-one Flurtamone C18H14F3NO2 CNC1=C(C(=O)C(O1)C2=CC=CC=C2)C3=CC(=CC=C3)C(F)(F)F InChI=1S/C18H14F3NO2/c1-22-17-14(12-8-5-9-13(10-12)18(19,20)21)15(23)16(24-17)11-6-3-2-4-7-11/h2-10,16,22H,1H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Czech Republic - CoRMS: Ireland Flurtamone Active substance data 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance flurtamone 06Jun2016 2016 doi: 10.2903/j.efsa.2016.4498
+Flurtamone 619-224-0 96525-23-4 mixture or formulation Component is identical to the substance Flurtamone 619-224-0 96525-23-4 (RS)-5-methylamino-2-phenyl-4-(α,α,α-trifluoro-m-tolyl)furan-3(2H)-one Flurtamone C18H14F3NO2 CNC1=C(C(=O)C(O1)C2=CC=CC=C2)C3=CC(=CC=C3)C(F)(F)F InChI=1S/C18H14F3NO2/c1-22-17-14(12-8-5-9-13(10-12)18(19,20)21)15(23)16(24-17)11-6-3-2-4-7-11/h2-10,16,22H,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: Czech Republic - CoRMS: Ireland Flurtamone Active substance data 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance flurtamone 06Jun2016 2016 doi: 10.2903/j.efsa.2016.4498
+Flurtamone 619-224-0 96525-23-4 mixture or formulation Component is identical to the substance Flurtamone 619-224-0 96525-23-4 (RS)-5-methylamino-2-phenyl-4-(α,α,α-trifluoro-m-tolyl)furan-3(2H)-one Flurtamone C18H14F3NO2 CNC1=C(C(=O)C(O1)C2=CC=CC=C2)C3=CC(=CC=C3)C(F)(F)F InChI=1S/C18H14F3NO2/c1-22-17-14(12-8-5-9-13(10-12)18(19,20)21)15(23)16(24-17)11-6-3-2-4-7-11/h2-10,16,22H,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: Czech Republic - CoRMS: Ireland Flurtamone Active substance data 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance flurtamone 06Jun2016 2016 doi: 10.2903/j.efsa.2016.4498
+Flurtamone 619-224-0 96525-23-4 mixture or formulation Component is identical to the substance Flurtamone 619-224-0 96525-23-4 (RS)-5-methylamino-2-phenyl-4-(α,α,α-trifluoro-m-tolyl)furan-3(2H)-one Flurtamone C18H14F3NO2 CNC1=C(C(=O)C(O1)C2=CC=CC=C2)C3=CC(=CC=C3)C(F)(F)F InChI=1S/C18H14F3NO2/c1-22-17-14(12-8-5-9-13(10-12)18(19,20)21)15(23)16(24-17)11-6-3-2-4-7-11/h2-10,16,22H,1H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported yes, concurrent vehicle without Negative RMS: Czech Republic - CoRMS: Ireland Flurtamone Active substance data 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance flurtamone 06Jun2016 2016 doi: 10.2903/j.efsa.2016.4498
+Flurtamone 619-224-0 96525-23-4 mixture or formulation Component is identical to the substance Flurtamone 619-224-0 96525-23-4 (RS)-5-methylamino-2-phenyl-4-(α,α,α-trifluoro-m-tolyl)furan-3(2H)-one Flurtamone C18H14F3NO2 CNC1=C(C(=O)C(O1)C2=CC=CC=C2)C3=CC(=CC=C3)C(F)(F)F InChI=1S/C18H14F3NO2/c1-22-17-14(12-8-5-9-13(10-12)18(19,20)21)15(23)16(24-17)11-6-3-2-4-7-11/h2-10,16,22H,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration mammalian germ cell cytogenetic assay in vivo No guideline followed Not reported No Acceptable Rat (as animal) Sprague-Dawley 30 Male/Female oral: gavage 12.0000000000 h yes not applicable Negative RMS: Czech Republic - CoRMS: Ireland Flurtamone Active substance data 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance flurtamone 06Jun2016 2016 doi: 10.2903/j.efsa.2016.4498
+Flurtamone 619-224-0 96525-23-4 mixture or formulation Component is identical to the substance Flurtamone 619-224-0 96525-23-4 (RS)-5-methylamino-2-phenyl-4-(α,α,α-trifluoro-m-tolyl)furan-3(2H)-one Flurtamone C18H14F3NO2 CNC1=C(C(=O)C(O1)C2=CC=CC=C2)C3=CC(=CC=C3)C(F)(F)F InChI=1S/C18H14F3NO2/c1-22-17-14(12-8-5-9-13(10-12)18(19,20)21)15(23)16(24-17)11-6-3-2-4-7-11/h2-10,16,22H,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration mammalian germ cell cytogenetic assay in vivo No guideline followed Not reported No Acceptable Rat (as animal) Sprague-Dawley 30 Male/Female oral: gavage 48.0000000000 h yes not applicable Negative RMS: Czech Republic - CoRMS: Ireland Flurtamone Active substance data 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance flurtamone 06Jun2016 2016 doi: 10.2903/j.efsa.2016.4498
+Flurtamone 619-224-0 96525-23-4 mixture or formulation Component is identical to the substance Flurtamone 619-224-0 96525-23-4 (RS)-5-methylamino-2-phenyl-4-(α,α,α-trifluoro-m-tolyl)furan-3(2H)-one Flurtamone C18H14F3NO2 CNC1=C(C(=O)C(O1)C2=CC=CC=C2)C3=CC(=CC=C3)C(F)(F)F InChI=1S/C18H14F3NO2/c1-22-17-14(12-8-5-9-13(10-12)18(19,20)21)15(23)16(24-17)11-6-3-2-4-7-11/h2-10,16,22H,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration mammalian germ cell cytogenetic assay in vivo No guideline followed Not reported No Acceptable Rat (as animal) Sprague-Dawley 30 Male/Female oral: gavage 24.0000000000 h yes not applicable Negative RMS: Czech Republic - CoRMS: Ireland Flurtamone Active substance data 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance flurtamone 06Jun2016 2016 doi: 10.2903/j.efsa.2016.4498
+Flurtamone 619-224-0 96525-23-4 mixture or formulation Component is identical to the substance Flurtamone 619-224-0 96525-23-4 (RS)-5-methylamino-2-phenyl-4-(α,α,α-trifluoro-m-tolyl)furan-3(2H)-one Flurtamone C18H14F3NO2 CNC1=C(C(=O)C(O1)C2=CC=CC=C2)C3=CC(=CC=C3)C(F)(F)F InChI=1S/C18H14F3NO2/c1-22-17-14(12-8-5-9-13(10-12)18(19,20)21)15(23)16(24-17)11-6-3-2-4-7-11/h2-10,16,22H,1H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo Equivalent or similar to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Yes Acceptable House mouse (as animal) Not reported 12 Male/Female oral: unspecified 48.0000000000 h yes not applicable Negative no evidence RMS: Czech Republic - CoRMS: Ireland Flurtamone Active substance data 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance flurtamone 06Jun2016 2016 doi: 10.2903/j.efsa.2016.4498
+Flurtamone 619-224-0 96525-23-4 single chemical entity Component is a metabolite of the substance Trifluoroacetic acid 200-929-3 76-05-1 2,2,2-trifluoroacetic acid Not in list C2HF3O2 C(=O)(C(F)(F)F)O InChI=1S/C2HF3O2/c3-2(4,5)1(6)7/h(H,6,7) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Czech Republic - CoRMS: Ireland Flurtamone Active substance data 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance flurtamone 06Jun2016 2016 doi: 10.2903/j.efsa.2016.4498
+Flurtamone 619-224-0 96525-23-4 single chemical entity Component is a metabolite of the substance Trifluoroacetic acid 200-929-3 76-05-1 2,2,2-trifluoroacetic acid Not in list C2HF3O2 C(=O)(C(F)(F)F)O InChI=1S/C2HF3O2/c3-2(4,5)1(6)7/h(H,6,7) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Czech Republic - CoRMS: Ireland Flurtamone Active substance data 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance flurtamone 06Jun2016 2016 doi: 10.2903/j.efsa.2016.4498
+Flurtamone 619-224-0 96525-23-4 single chemical entity Component is a metabolite of the substance Trifluoroacetic acid 200-929-3 76-05-1 2,2,2-trifluoroacetic acid Not in list C2HF3O2 C(=O)(C(F)(F)F)O InChI=1S/C2HF3O2/c3-2(4,5)1(6)7/h(H,6,7) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Czech Republic - CoRMS: Ireland Flurtamone Active substance data 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance flurtamone 06Jun2016 2016 doi: 10.2903/j.efsa.2016.4498
+Flurtamone 619-224-0 96525-23-4 single chemical entity Component is a metabolite of the substance Trifluoroacetic acid 200-929-3 76-05-1 2,2,2-trifluoroacetic acid Not in list C2HF3O2 C(=O)(C(F)(F)F)O InChI=1S/C2HF3O2/c3-2(4,5)1(6)7/h(H,6,7) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Czech Republic - CoRMS: Ireland Flurtamone Active substance data 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance flurtamone 06Jun2016 2016 doi: 10.2903/j.efsa.2016.4498
+Flurtamone 619-224-0 96525-23-4 single chemical entity Component is a metabolite of the substance Trifluoroacetic acid 200-929-3 76-05-1 2,2,2-trifluoroacetic acid Not in list C2HF3O2 C(=O)(C(F)(F)F)O InChI=1S/C2HF3O2/c3-2(4,5)1(6)7/h(H,6,7) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Czech Republic - CoRMS: Ireland Flurtamone Active substance data 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance flurtamone 06Jun2016 2016 doi: 10.2903/j.efsa.2016.4498
+Flurtamone 619-224-0 96525-23-4 single chemical entity Component is a metabolite of the substance Trifluoroacetic acid 200-929-3 76-05-1 2,2,2-trifluoroacetic acid Not in list C2HF3O2 C(=O)(C(F)(F)F)O InChI=1S/C2HF3O2/c3-2(4,5)1(6)7/h(H,6,7) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Czech Republic - CoRMS: Ireland Flurtamone Active substance data 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance flurtamone 06Jun2016 2016 doi: 10.2903/j.efsa.2016.4498
+Flurtamone 619-224-0 96525-23-4 single chemical entity Component is a metabolite of the substance Trifluoroacetic acid 200-929-3 76-05-1 2,2,2-trifluoroacetic acid Not in list C2HF3O2 C(=O)(C(F)(F)F)O InChI=1S/C2HF3O2/c3-2(4,5)1(6)7/h(H,6,7) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Czech Republic - CoRMS: Ireland Flurtamone Active substance data 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance flurtamone 06Jun2016 2016 doi: 10.2903/j.efsa.2016.4498
+Flurtamone 619-224-0 96525-23-4 single chemical entity Component is a metabolite of the substance Trifluoroacetic acid 200-929-3 76-05-1 2,2,2-trifluoroacetic acid Not in list C2HF3O2 C(=O)(C(F)(F)F)O InChI=1S/C2HF3O2/c3-2(4,5)1(6)7/h(H,6,7) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Czech Republic - CoRMS: Ireland Flurtamone Active substance data 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance flurtamone 06Jun2016 2016 doi: 10.2903/j.efsa.2016.4498
+Flurtamone 619-224-0 96525-23-4 single chemical entity Component is a metabolite of the substance Trifluoroacetic acid 200-929-3 76-05-1 2,2,2-trifluoroacetic acid Not in list C2HF3O2 C(=O)(C(F)(F)F)O InChI=1S/C2HF3O2/c3-2(4,5)1(6)7/h(H,6,7) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Czech Republic - CoRMS: Ireland Flurtamone Active substance data 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance flurtamone 06Jun2016 2016 doi: 10.2903/j.efsa.2016.4498
+Flurtamone 619-224-0 96525-23-4 single chemical entity Component is a metabolite of the substance Trifluoroacetic acid 200-929-3 76-05-1 2,2,2-trifluoroacetic acid Not in list C2HF3O2 C(=O)(C(F)(F)F)O InChI=1S/C2HF3O2/c3-2(4,5)1(6)7/h(H,6,7) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Czech Republic - CoRMS: Ireland Flurtamone Active substance data 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance flurtamone 06Jun2016 2016 doi: 10.2903/j.efsa.2016.4498
+Flurtamone 619-224-0 96525-23-4 single chemical entity Component is a metabolite of the substance Trifluoroacetic acid 200-929-3 76-05-1 2,2,2-trifluoroacetic acid Not in list C2HF3O2 C(=O)(C(F)(F)F)O InChI=1S/C2HF3O2/c3-2(4,5)1(6)7/h(H,6,7) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle with Negative no information RMS: Czech Republic - CoRMS: Ireland Flurtamone Active substance data 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance flurtamone 06Jun2016 2016 doi: 10.2903/j.efsa.2016.4498
+Flurtamone 619-224-0 96525-23-4 single chemical entity Component is a metabolite of the substance Trifluoroacetic acid 200-929-3 76-05-1 2,2,2-trifluoroacetic acid Not in list C2HF3O2 C(=O)(C(F)(F)F)O InChI=1S/C2HF3O2/c3-2(4,5)1(6)7/h(H,6,7) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes, concurrent vehicle without Negative no information RMS: Czech Republic - CoRMS: Ireland Flurtamone Active substance data 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance flurtamone 06Jun2016 2016 doi: 10.2903/j.efsa.2016.4498
+Flurtamone 619-224-0 96525-23-4 single chemical entity Component is a metabolite of the substance Trifluoroacetic acid 200-929-3 76-05-1 2,2,2-trifluoroacetic acid Not in list C2HF3O2 C(=O)(C(F)(F)F)O InChI=1S/C2HF3O2/c3-2(4,5)1(6)7/h(H,6,7) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes with Negative RMS: Czech Republic - CoRMS: Ireland Flurtamone Active substance data 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance flurtamone 06Jun2016 2016 doi: 10.2903/j.efsa.2016.4498
+Flurtamone 619-224-0 96525-23-4 single chemical entity Component is a metabolite of the substance Trifluoroacetic acid 200-929-3 76-05-1 2,2,2-trifluoroacetic acid Not in list C2HF3O2 C(=O)(C(F)(F)F)O InChI=1S/C2HF3O2/c3-2(4,5)1(6)7/h(H,6,7) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes without Negative RMS: Czech Republic - CoRMS: Ireland Flurtamone Active substance data 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance flurtamone 06Jun2016 2016 doi: 10.2903/j.efsa.2016.4498
+Flurtamone 619-224-0 96525-23-4 single chemical entity Component is a metabolite of the substance 3-(trifluoromethyl)benzoic acid 207-230-2 454-92-2 3-(trifluoromethyl)benzoic acid Not in list C8H5F3O2 FC(F)(F)c1cccc(c1)C(=O)O InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle without Negative RMS: Czech Republic - CoRMS: Ireland Flurtamone Active substance data 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance flurtamone 06Jun2016 2016 doi: 10.2903/j.efsa.2016.4498
+Flurtamone 619-224-0 96525-23-4 single chemical entity Component is a metabolite of the substance 3-(trifluoromethyl)benzoic acid 207-230-2 454-92-2 3-(trifluoromethyl)benzoic acid Not in list C8H5F3O2 FC(F)(F)c1cccc(c1)C(=O)O InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle without Negative RMS: Czech Republic - CoRMS: Ireland Flurtamone Active substance data 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance flurtamone 06Jun2016 2016 doi: 10.2903/j.efsa.2016.4498
+Flurtamone 619-224-0 96525-23-4 single chemical entity Component is a metabolite of the substance 3-(trifluoromethyl)benzoic acid 207-230-2 454-92-2 3-(trifluoromethyl)benzoic acid Not in list C8H5F3O2 FC(F)(F)c1cccc(c1)C(=O)O InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: Czech Republic - CoRMS: Ireland Flurtamone Active substance data 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance flurtamone 06Jun2016 2016 doi: 10.2903/j.efsa.2016.4498
+Flurtamone 619-224-0 96525-23-4 single chemical entity Component is a metabolite of the substance 3-(trifluoromethyl)benzoic acid 207-230-2 454-92-2 3-(trifluoromethyl)benzoic acid Not in list C8H5F3O2 FC(F)(F)c1cccc(c1)C(=O)O InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle without Negative RMS: Czech Republic - CoRMS: Ireland Flurtamone Active substance data 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance flurtamone 06Jun2016 2016 doi: 10.2903/j.efsa.2016.4498
+Flurtamone 619-224-0 96525-23-4 single chemical entity Component is a metabolite of the substance 3-(trifluoromethyl)benzoic acid 207-230-2 454-92-2 3-(trifluoromethyl)benzoic acid Not in list C8H5F3O2 FC(F)(F)c1cccc(c1)C(=O)O InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported yes, concurrent vehicle with Negative RMS: Czech Republic - CoRMS: Ireland Flurtamone Active substance data 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance flurtamone 06Jun2016 2016 doi: 10.2903/j.efsa.2016.4498
+Flurtamone 619-224-0 96525-23-4 single chemical entity Component is a metabolite of the substance 3-(trifluoromethyl)benzoic acid 207-230-2 454-92-2 3-(trifluoromethyl)benzoic acid Not in list C8H5F3O2 FC(F)(F)c1cccc(c1)C(=O)O InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: Czech Republic - CoRMS: Ireland Flurtamone Active substance data 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance flurtamone 06Jun2016 2016 doi: 10.2903/j.efsa.2016.4498
+Flurtamone 619-224-0 96525-23-4 single chemical entity Component is a metabolite of the substance 3-(trifluoromethyl)benzoic acid 207-230-2 454-92-2 3-(trifluoromethyl)benzoic acid Not in list C8H5F3O2 FC(F)(F)c1cccc(c1)C(=O)O InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported yes, concurrent vehicle with Negative RMS: Czech Republic - CoRMS: Ireland Flurtamone Active substance data 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance flurtamone 06Jun2016 2016 doi: 10.2903/j.efsa.2016.4498
+Flurtamone 619-224-0 96525-23-4 single chemical entity Component is a metabolite of the substance 3-(trifluoromethyl)benzoic acid 207-230-2 454-92-2 3-(trifluoromethyl)benzoic acid Not in list C8H5F3O2 FC(F)(F)c1cccc(c1)C(=O)O InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle with Negative RMS: Czech Republic - CoRMS: Ireland Flurtamone Active substance data 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance flurtamone 06Jun2016 2016 doi: 10.2903/j.efsa.2016.4498
+Flurtamone 619-224-0 96525-23-4 single chemical entity Component is a metabolite of the substance 3-(trifluoromethyl)benzoic acid 207-230-2 454-92-2 3-(trifluoromethyl)benzoic acid Not in list C8H5F3O2 FC(F)(F)c1cccc(c1)C(=O)O InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported yes, concurrent vehicle with Negative RMS: Czech Republic - CoRMS: Ireland Flurtamone Active substance data 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance flurtamone 06Jun2016 2016 doi: 10.2903/j.efsa.2016.4498
+Flurtamone 619-224-0 96525-23-4 single chemical entity Component is a metabolite of the substance 3-(trifluoromethyl)benzoic acid 207-230-2 454-92-2 3-(trifluoromethyl)benzoic acid Not in list C8H5F3O2 FC(F)(F)c1cccc(c1)C(=O)O InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported yes, concurrent vehicle without Negative RMS: Czech Republic - CoRMS: Ireland Flurtamone Active substance data 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance flurtamone 06Jun2016 2016 doi: 10.2903/j.efsa.2016.4498
+Flurtamone 619-224-0 96525-23-4 single chemical entity Component is a metabolite of the substance 3-(trifluoromethyl)benzoic acid 207-230-2 454-92-2 3-(trifluoromethyl)benzoic acid Not in list C8H5F3O2 FC(F)(F)c1cccc(c1)C(=O)O InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes without Negative RMS: Czech Republic - CoRMS: Ireland Flurtamone Active substance data 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance flurtamone 06Jun2016 2016 doi: 10.2903/j.efsa.2016.4498
+Flurtamone 619-224-0 96525-23-4 single chemical entity Component is a metabolite of the substance 3-(trifluoromethyl)benzoic acid 207-230-2 454-92-2 3-(trifluoromethyl)benzoic acid Not in list C8H5F3O2 FC(F)(F)c1cccc(c1)C(=O)O InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported yes with Negative RMS: Czech Republic - CoRMS: Ireland Flurtamone Active substance data 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance flurtamone 06Jun2016 2016 doi: 10.2903/j.efsa.2016.4498
+Flurtamone 619-224-0 96525-23-4 single chemical entity Component is a metabolite of the substance 3-(trifluoromethyl)benzoic acid 207-230-2 454-92-2 3-(trifluoromethyl)benzoic acid Not in list C8H5F3O2 FC(F)(F)c1cccc(c1)C(=O)O InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative small colonies RMS: Czech Republic - CoRMS: Ireland Flurtamone Active substance data 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance flurtamone 06Jun2016 2016 doi: 10.2903/j.efsa.2016.4498
+Flurtamone 619-224-0 96525-23-4 single chemical entity Component is a metabolite of the substance 3-(trifluoromethyl)benzoic acid 207-230-2 454-92-2 3-(trifluoromethyl)benzoic acid Not in list C8H5F3O2 FC(F)(F)c1cccc(c1)C(=O)O InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Positive small colonies RMS: Czech Republic - CoRMS: Ireland Flurtamone Active substance data 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance flurtamone 06Jun2016 2016 doi: 10.2903/j.efsa.2016.4498
+Flurtamone 619-224-0 96525-23-4 single chemical entity Component is a metabolite of the substance 3-(trifluoromethyl)benzoic acid 207-230-2 454-92-2 3-(trifluoromethyl)benzoic acid Not in list C8H5F3O2 FC(F)(F)c1cccc(c1)C(=O)O InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes without Negative large colonies RMS: Czech Republic - CoRMS: Ireland Flurtamone Active substance data 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance flurtamone 06Jun2016 2016 doi: 10.2903/j.efsa.2016.4498
+Flurtamone 619-224-0 96525-23-4 single chemical entity Component is a metabolite of the substance 3-(trifluoromethyl)benzoic acid 207-230-2 454-92-2 3-(trifluoromethyl)benzoic acid Not in list C8H5F3O2 FC(F)(F)c1cccc(c1)C(=O)O InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported yes with Positive large colonies RMS: Czech Republic - CoRMS: Ireland Flurtamone Active substance data 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance flurtamone 06Jun2016 2016 doi: 10.2903/j.efsa.2016.4498
+Flurtamone 619-224-0 96525-23-4 single chemical entity Component is a metabolite of the substance 3-(trifluoromethyl)benzoic acid 207-230-2 454-92-2 3-(trifluoromethyl)benzoic acid Not in list C8H5F3O2 FC(F)(F)c1cccc(c1)C(=O)O InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 6 Male oral: gavage 24.0000000000 h yes, concurrent vehicle not applicable Negative no evidence RMS: Czech Republic - CoRMS: Ireland Flurtamone Active substance data 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance flurtamone 06Jun2016 2016 doi: 10.2903/j.efsa.2016.4498
+Flurtamone 619-224-0 96525-23-4 single chemical entity Component is a metabolite of the substance 3-(trifluoromethyl)benzoic acid 207-230-2 454-92-2 3-(trifluoromethyl)benzoic acid Not in list C8H5F3O2 FC(F)(F)c1cccc(c1)C(=O)O InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Wistar 4 Male oral: gavage 12.0000000000 h yes not applicable Negative RMS: Czech Republic - CoRMS: Ireland Flurtamone Active substance data 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance flurtamone 06Jun2016 2016 doi: 10.2903/j.efsa.2016.4498
+Flurtamone 619-224-0 96525-23-4 single chemical entity Component is a metabolite of the substance 3-(trifluoromethyl)benzoic acid 207-230-2 454-92-2 3-(trifluoromethyl)benzoic acid Not in list C8H5F3O2 FC(F)(F)c1cccc(c1)C(=O)O InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13) organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair unscheduled DNA synthesis in vivo According to OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo) No Acceptable Rat (as animal) Wistar 4 Male oral: gavage 2.0000000000 h yes not applicable Negative RMS: Czech Republic - CoRMS: Ireland Flurtamone Active substance data 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance flurtamone 06Jun2016 2016 doi: 10.2903/j.efsa.2016.4498
+Thiodicarb 261-848-7 59669-26-0 single chemical entity Component is identical to the substance Thiodicarb 261-848-7 59669-26-0 Methyl N-[methyl-[methyl-(1-methylsulfanylethylideneamino)oxycarbonylamino] sulfanylcarbamoyl]oxyethanimidothioate Thiodicarb C10H18N4O4S3 CC(=NOC(=O)N(C)SN(C)C(=O)ON=C(C)SC)SC InChI=1S/C10H18N4O4S3/c1-7(19-5)11-17-9(15)13(3)21-14(4)10(16)18-12-8(2)20-6/h1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data with Negative RMS: The United Kingdom Thiodicarb (Final addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance thiodicarb 30Jan2006 2006 doi:10.2903/j.efsa.2006.55r
+Thiodicarb 261-848-7 59669-26-0 single chemical entity Component is identical to the substance Thiodicarb 261-848-7 59669-26-0 Methyl N-[methyl-[methyl-(1-methylsulfanylethylideneamino)oxycarbonylamino] sulfanylcarbamoyl]oxyethanimidothioate Thiodicarb C10H18N4O4S3 CC(=NOC(=O)N(C)SN(C)C(=O)ON=C(C)SC)SC InChI=1S/C10H18N4O4S3/c1-7(19-5)11-17-9(15)13(3)21-14(4)10(16)18-12-8(2)20-6/h1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data with Negative RMS: The United Kingdom Thiodicarb (Final addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance thiodicarb 30Jan2006 2006 doi:10.2903/j.efsa.2006.55r
+Thiodicarb 261-848-7 59669-26-0 single chemical entity Component is identical to the substance Thiodicarb 261-848-7 59669-26-0 Methyl N-[methyl-[methyl-(1-methylsulfanylethylideneamino)oxycarbonylamino] sulfanylcarbamoyl]oxyethanimidothioate Thiodicarb C10H18N4O4S3 CC(=NOC(=O)N(C)SN(C)C(=O)ON=C(C)SC)SC InChI=1S/C10H18N4O4S3/c1-7(19-5)11-17-9(15)13(3)21-14(4)10(16)18-12-8(2)20-6/h1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1538 Not reported no data without Negative RMS: The United Kingdom Thiodicarb (Final addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance thiodicarb 30Jan2006 2006 doi:10.2903/j.efsa.2006.55r
+Thiodicarb 261-848-7 59669-26-0 single chemical entity Component is identical to the substance Thiodicarb 261-848-7 59669-26-0 Methyl N-[methyl-[methyl-(1-methylsulfanylethylideneamino)oxycarbonylamino] sulfanylcarbamoyl]oxyethanimidothioate Thiodicarb C10H18N4O4S3 CC(=NOC(=O)N(C)SN(C)C(=O)ON=C(C)SC)SC InChI=1S/C10H18N4O4S3/c1-7(19-5)11-17-9(15)13(3)21-14(4)10(16)18-12-8(2)20-6/h1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data without Negative RMS: The United Kingdom Thiodicarb (Final addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance thiodicarb 30Jan2006 2006 doi:10.2903/j.efsa.2006.55r
+Thiodicarb 261-848-7 59669-26-0 single chemical entity Component is identical to the substance Thiodicarb 261-848-7 59669-26-0 Methyl N-[methyl-[methyl-(1-methylsulfanylethylideneamino)oxycarbonylamino] sulfanylcarbamoyl]oxyethanimidothioate Thiodicarb C10H18N4O4S3 CC(=NOC(=O)N(C)SN(C)C(=O)ON=C(C)SC)SC InChI=1S/C10H18N4O4S3/c1-7(19-5)11-17-9(15)13(3)21-14(4)10(16)18-12-8(2)20-6/h1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data with Negative RMS: The United Kingdom Thiodicarb (Final addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance thiodicarb 30Jan2006 2006 doi:10.2903/j.efsa.2006.55r
+Thiodicarb 261-848-7 59669-26-0 single chemical entity Component is identical to the substance Thiodicarb 261-848-7 59669-26-0 Methyl N-[methyl-[methyl-(1-methylsulfanylethylideneamino)oxycarbonylamino] sulfanylcarbamoyl]oxyethanimidothioate Thiodicarb C10H18N4O4S3 CC(=NOC(=O)N(C)SN(C)C(=O)ON=C(C)SC)SC InChI=1S/C10H18N4O4S3/c1-7(19-5)11-17-9(15)13(3)21-14(4)10(16)18-12-8(2)20-6/h1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 98 Not reported no data with Negative RMS: The United Kingdom Thiodicarb (Final addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance thiodicarb 30Jan2006 2006 doi:10.2903/j.efsa.2006.55r
+Thiodicarb 261-848-7 59669-26-0 single chemical entity Component is identical to the substance Thiodicarb 261-848-7 59669-26-0 Methyl N-[methyl-[methyl-(1-methylsulfanylethylideneamino)oxycarbonylamino] sulfanylcarbamoyl]oxyethanimidothioate Thiodicarb C10H18N4O4S3 CC(=NOC(=O)N(C)SN(C)C(=O)ON=C(C)SC)SC InChI=1S/C10H18N4O4S3/c1-7(19-5)11-17-9(15)13(3)21-14(4)10(16)18-12-8(2)20-6/h1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data with Negative RMS: The United Kingdom Thiodicarb (Final addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance thiodicarb 30Jan2006 2006 doi:10.2903/j.efsa.2006.55r
+Thiodicarb 261-848-7 59669-26-0 single chemical entity Component is identical to the substance Thiodicarb 261-848-7 59669-26-0 Methyl N-[methyl-[methyl-(1-methylsulfanylethylideneamino)oxycarbonylamino] sulfanylcarbamoyl]oxyethanimidothioate Thiodicarb C10H18N4O4S3 CC(=NOC(=O)N(C)SN(C)C(=O)ON=C(C)SC)SC InChI=1S/C10H18N4O4S3/c1-7(19-5)11-17-9(15)13(3)21-14(4)10(16)18-12-8(2)20-6/h1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 100 Not reported no data without Negative RMS: The United Kingdom Thiodicarb (Final addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance thiodicarb 30Jan2006 2006 doi:10.2903/j.efsa.2006.55r
+Thiodicarb 261-848-7 59669-26-0 single chemical entity Component is identical to the substance Thiodicarb 261-848-7 59669-26-0 Methyl N-[methyl-[methyl-(1-methylsulfanylethylideneamino)oxycarbonylamino] sulfanylcarbamoyl]oxyethanimidothioate Thiodicarb C10H18N4O4S3 CC(=NOC(=O)N(C)SN(C)C(=O)ON=C(C)SC)SC InChI=1S/C10H18N4O4S3/c1-7(19-5)11-17-9(15)13(3)21-14(4)10(16)18-12-8(2)20-6/h1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1537 Not reported no data without Negative RMS: The United Kingdom Thiodicarb (Final addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance thiodicarb 30Jan2006 2006 doi:10.2903/j.efsa.2006.55r
+Thiodicarb 261-848-7 59669-26-0 single chemical entity Component is identical to the substance Thiodicarb 261-848-7 59669-26-0 Methyl N-[methyl-[methyl-(1-methylsulfanylethylideneamino)oxycarbonylamino] sulfanylcarbamoyl]oxyethanimidothioate Thiodicarb C10H18N4O4S3 CC(=NOC(=O)N(C)SN(C)C(=O)ON=C(C)SC)SC InChI=1S/C10H18N4O4S3/c1-7(19-5)11-17-9(15)13(3)21-14(4)10(16)18-12-8(2)20-6/h1-6H3 organic compound PubChem canonical SMILES PubChem InChI gene mutation bacterial reverse mutation assay in vitro Equivalent or similar to OECD Guideline 471 (Bacterial Reverse Mutation Assay) Yes Acceptable Salmonella typhimurium (as organism) TA 1535 Not reported no data without Negative RMS: The United Kingdom Thiodicarb (Final addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance thiodicarb 30Jan2006 2006 doi:10.2903/j.efsa.2006.55r
+Thiodicarb 261-848-7 59669-26-0 single chemical entity Component is identical to the substance Thiodicarb 261-848-7 59669-26-0 Methyl N-[methyl-[methyl-(1-methylsulfanylethylideneamino)oxycarbonylamino] sulfanylcarbamoyl]oxyethanimidothioate Thiodicarb C10H18N4O4S3 CC(=NOC(=O)N(C)SN(C)C(=O)ON=C(C)SC)SC InChI=1S/C10H18N4O4S3/c1-7(19-5)11-17-9(15)13(3)21-14(4)10(16)18-12-8(2)20-6/h1-6H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) (k12)p3478 Not reported no data with Negative RMS: The United Kingdom Thiodicarb (Final addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance thiodicarb 30Jan2006 2006 doi:10.2903/j.efsa.2006.55r
+Thiodicarb 261-848-7 59669-26-0 single chemical entity Component is identical to the substance Thiodicarb 261-848-7 59669-26-0 Methyl N-[methyl-[methyl-(1-methylsulfanylethylideneamino)oxycarbonylamino] sulfanylcarbamoyl]oxyethanimidothioate Thiodicarb C10H18N4O4S3 CC(=NOC(=O)N(C)SN(C)C(=O)ON=C(C)SC)SC InChI=1S/C10H18N4O4S3/c1-7(19-5)11-17-9(15)13(3)21-14(4)10(16)18-12-8(2)20-6/h1-6H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) W3110 Not reported no data with Negative RMS: The United Kingdom Thiodicarb (Final addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance thiodicarb 30Jan2006 2006 doi:10.2903/j.efsa.2006.55r
+Thiodicarb 261-848-7 59669-26-0 single chemical entity Component is identical to the substance Thiodicarb 261-848-7 59669-26-0 Methyl N-[methyl-[methyl-(1-methylsulfanylethylideneamino)oxycarbonylamino] sulfanylcarbamoyl]oxyethanimidothioate Thiodicarb C10H18N4O4S3 CC(=NOC(=O)N(C)SN(C)C(=O)ON=C(C)SC)SC InChI=1S/C10H18N4O4S3/c1-7(19-5)11-17-9(15)13(3)21-14(4)10(16)18-12-8(2)20-6/h1-6H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) (k12)p3478 Not reported no data without Negative RMS: The United Kingdom Thiodicarb (Final addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance thiodicarb 30Jan2006 2006 doi:10.2903/j.efsa.2006.55r
+Thiodicarb 261-848-7 59669-26-0 single chemical entity Component is identical to the substance Thiodicarb 261-848-7 59669-26-0 Methyl N-[methyl-[methyl-(1-methylsulfanylethylideneamino)oxycarbonylamino] sulfanylcarbamoyl]oxyethanimidothioate Thiodicarb C10H18N4O4S3 CC(=NOC(=O)N(C)SN(C)C(=O)ON=C(C)SC)SC InChI=1S/C10H18N4O4S3/c1-7(19-5)11-17-9(15)13(3)21-14(4)10(16)18-12-8(2)20-6/h1-6H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair other in vitro No guideline available Not reported Not applicable Acceptable Escherichia coli (as organism) W3110 Not reported no data without Negative RMS: The United Kingdom Thiodicarb (Final addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance thiodicarb 30Jan2006 2006 doi:10.2903/j.efsa.2006.55r
+Thiodicarb 261-848-7 59669-26-0 single chemical entity Component is identical to the substance Thiodicarb 261-848-7 59669-26-0 Methyl N-[methyl-[methyl-(1-methylsulfanylethylideneamino)oxycarbonylamino] sulfanylcarbamoyl]oxyethanimidothioate Thiodicarb C10H18N4O4S3 CC(=NOC(=O)N(C)SN(C)C(=O)ON=C(C)SC)SC InChI=1S/C10H18N4O4S3/c1-7(19-5)11-17-9(15)13(3)21-14(4)10(16)18-12-8(2)20-6/h1-6H3 organic compound PubChem canonical SMILES PubChem InChI genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro No guideline followed Not reported No Acceptable Saccharomyces cerevisiae (as organism) D7 Not reported no data without Negative RMS: The United Kingdom Thiodicarb (Final addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance thiodicarb 30Jan2006 2006 doi:10.2903/j.efsa.2006.55r
+Thiodicarb 261-848-7 59669-26-0 single chemical entity Component is identical to the substance Thiodicarb 261-848-7 59669-26-0 Methyl N-[methyl-[methyl-(1-methylsulfanylethylideneamino)oxycarbonylamino] sulfanylcarbamoyl]oxyethanimidothioate Thiodicarb C10H18N4O4S3 CC(=NOC(=O)N(C)SN(C)C(=O)ON=C(C)SC)SC InChI=1S/C10H18N4O4S3/c1-7(19-5)11-17-9(15)13(3)21-14(4)10(16)18-12-8(2)20-6/h1-6H3 organic compound PubChem canonical SMILES PubChem InChI genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro According to OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay) No Acceptable Saccharomyces cerevisiae (as organism) D7 Not reported no data without Negative RMS: The United Kingdom Thiodicarb (Final addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance thiodicarb 30Jan2006 2006 doi:10.2903/j.efsa.2006.55r
+Thiodicarb 261-848-7 59669-26-0 single chemical entity Component is identical to the substance Thiodicarb 261-848-7 59669-26-0 Methyl N-[methyl-[methyl-(1-methylsulfanylethylideneamino)oxycarbonylamino] sulfanylcarbamoyl]oxyethanimidothioate Thiodicarb C10H18N4O4S3 CC(=NOC(=O)N(C)SN(C)C(=O)ON=C(C)SC)SC InChI=1S/C10H18N4O4S3/c1-7(19-5)11-17-9(15)13(3)21-14(4)10(16)18-12-8(2)20-6/h1-6H3 organic compound PubChem canonical SMILES PubChem InChI genome mutation mitotic recombination in Saccharomyces cerevisiae in vitro No guideline followed Not reported No Acceptable Saccharomyces cerevisiae (as organism) D7 Not reported no data without Positive RMS: The United Kingdom Thiodicarb (Final addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance thiodicarb 30Jan2006 2006 doi:10.2903/j.efsa.2006.55r
+Thiodicarb 261-848-7 59669-26-0 single chemical entity Component is identical to the substance Thiodicarb 261-848-7 59669-26-0 Methyl N-[methyl-[methyl-(1-methylsulfanylethylideneamino)oxycarbonylamino] sulfanylcarbamoyl]oxyethanimidothioate Thiodicarb C10H18N4O4S3 CC(=NOC(=O)N(C)SN(C)C(=O)ON=C(C)SC)SC InChI=1S/C10H18N4O4S3/c1-7(19-5)11-17-9(15)13(3)21-14(4)10(16)18-12-8(2)20-6/h1-6H3 organic compound PubChem canonical SMILES PubChem InChI DNA damage and/or repair DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro in vitro According to OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro) No Acceptable Rat (as animal) hepatocytes Not reported no data without Negative RMS: The United Kingdom Thiodicarb (Final addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance thiodicarb 30Jan2006 2006 doi:10.2903/j.efsa.2006.55r
+Thiodicarb 261-848-7 59669-26-0 single chemical entity Component is identical to the substance Thiodicarb 261-848-7 59669-26-0 Methyl N-[methyl-[methyl-(1-methylsulfanylethylideneamino)oxycarbonylamino] sulfanylcarbamoyl]oxyethanimidothioate Thiodicarb C10H18N4O4S3 CC(=NOC(=O)N(C)SN(C)C(=O)ON=C(C)SC)SC InChI=1S/C10H18N4O4S3/c1-7(19-5)11-17-9(15)13(3)21-14(4)10(16)18-12-8(2)20-6/h1-6H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported no data without Negative RMS: The United Kingdom Thiodicarb (Final addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance thiodicarb 30Jan2006 2006 doi:10.2903/j.efsa.2006.55r
+Thiodicarb 261-848-7 59669-26-0 single chemical entity Component is identical to the substance Thiodicarb 261-848-7 59669-26-0 Methyl N-[methyl-[methyl-(1-methylsulfanylethylideneamino)oxycarbonylamino] sulfanylcarbamoyl]oxyethanimidothioate Thiodicarb C10H18N4O4S3 CC(=NOC(=O)N(C)SN(C)C(=O)ON=C(C)SC)SC InChI=1S/C10H18N4O4S3/c1-7(19-5)11-17-9(15)13(3)21-14(4)10(16)18-12-8(2)20-6/h1-6H3 organic compound PubChem canonical SMILES PubChem InChI chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Hamster (as animal) CHO Not reported no data with Negative RMS: The United Kingdom Thiodicarb (Final addendum) 2005 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance thiodicarb 30Jan2006 2006 doi:10.2903/j.efsa.2006.55r
+Sintofen (aka cintofen) 130561-48-7 single chemical entity Component is identical to the substance Sintofen (aka cintofen) 130561-48-7 1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid Sintofen (aka cintofen) C18H15ClN2O5 O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle without Negative RMS: France Sintofen (revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen 14Dec2010 2010 doi:10.2903/j.efsa.2010.1931
+Sintofen (aka cintofen) 130561-48-7 single chemical entity Component is identical to the substance Sintofen (aka cintofen) 130561-48-7 1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid Sintofen (aka cintofen) C18H15ClN2O5 O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) TA 102 Not reported yes, concurrent vehicle with Negative RMS: France Sintofen (revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen 14Dec2010 2010 doi:10.2903/j.efsa.2010.1931
+Sintofen (aka cintofen) 130561-48-7 single chemical entity Component is identical to the substance Sintofen (aka cintofen) 130561-48-7 1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid Sintofen (aka cintofen) C18H15ClN2O5 O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle without Negative RMS: France Sintofen (revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen 14Dec2010 2010 doi:10.2903/j.efsa.2010.1931
+Sintofen (aka cintofen) 130561-48-7 single chemical entity Component is identical to the substance Sintofen (aka cintofen) 130561-48-7 1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid Sintofen (aka cintofen) C18H15ClN2O5 O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) WP2 uvr A pKM 101 Not reported yes, concurrent vehicle with Negative RMS: France Sintofen (revised DAR) 2009 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen 14Dec2010 2010 doi:10.2903/j.efsa.2010.1931
+Tralkoxydim 87820-88-0 single chemical entity Component is a metabolite of the substance 3-(2,4,6-trimethylphenyl)pentanedioic acid 3-(2,4,6-trimethylphenyl)pentanedioic acid Not in list C14H18O4 OC(=O)CC(CC(O)=O)c1c(C)cc(C)cc1C InChI=1/C14H18O4/c1-8-4-9(2)14(10(3)5-8)11(6-12(15)16)7-13(17)18/h4-5,11H,6-7H2,1-3H3,(H,15,16)(H,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) Not reported Not reported no data with Negative RMS: The United Kingdom Tralkoxydim (Addendum 1) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim 28Jul2008 2008 doi:10.2903/j.efsa.2008.139r
+Tralkoxydim 87820-88-0 single chemical entity Component is a metabolite of the substance 3-(2,4,6-trimethylphenyl)pentanedioic acid 3-(2,4,6-trimethylphenyl)pentanedioic acid Not in list C14H18O4 OC(=O)CC(CC(O)=O)c1c(C)cc(C)cc1C InChI=1/C14H18O4/c1-8-4-9(2)14(10(3)5-8)11(6-12(15)16)7-13(17)18/h4-5,11H,6-7H2,1-3H3,(H,15,16)(H,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) Not reported Not reported no data with Negative RMS: The United Kingdom Tralkoxydim (Addendum 1) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim 28Jul2008 2008 doi:10.2903/j.efsa.2008.139r
+Tralkoxydim 87820-88-0 single chemical entity Component is a metabolite of the substance 3-(2,4,6-trimethylphenyl)pentanedioic acid 3-(2,4,6-trimethylphenyl)pentanedioic acid Not in list C14H18O4 OC(=O)CC(CC(O)=O)c1c(C)cc(C)cc1C InChI=1/C14H18O4/c1-8-4-9(2)14(10(3)5-8)11(6-12(15)16)7-13(17)18/h4-5,11H,6-7H2,1-3H3,(H,15,16)(H,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Escherichia coli (as organism) Not reported Not reported no data without Negative RMS: The United Kingdom Tralkoxydim (Addendum 1) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim 28Jul2008 2008 doi:10.2903/j.efsa.2008.139r
+Tralkoxydim 87820-88-0 single chemical entity Component is a metabolite of the substance 3-(2,4,6-trimethylphenyl)pentanedioic acid 3-(2,4,6-trimethylphenyl)pentanedioic acid Not in list C14H18O4 OC(=O)CC(CC(O)=O)c1c(C)cc(C)cc1C InChI=1/C14H18O4/c1-8-4-9(2)14(10(3)5-8)11(6-12(15)16)7-13(17)18/h4-5,11H,6-7H2,1-3H3,(H,15,16)(H,17,18) organic compound Other Other gene mutation bacterial reverse mutation assay in vitro According to OECD Guideline 471 (Bacterial Reverse Mutation Assay) No Acceptable Salmonella typhimurium (as organism) Not reported Not reported no data without Negative RMS: The United Kingdom Tralkoxydim (Addendum 1) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim 28Jul2008 2008 doi:10.2903/j.efsa.2008.139r
+Tralkoxydim 87820-88-0 single chemical entity Component is a metabolite of the substance 3-(2,4,6-trimethylphenyl)pentanedioic acid 3-(2,4,6-trimethylphenyl)pentanedioic acid Not in list C14H18O4 OC(=O)CC(CC(O)=O)c1c(C)cc(C)cc1C InChI=1/C14H18O4/c1-8-4-9(2)14(10(3)5-8)11(6-12(15)16)7-13(17)18/h4-5,11H,6-7H2,1-3H3,(H,15,16)(H,17,18) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data with Negative large colonies RMS: The United Kingdom Tralkoxydim (Addendum 1) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim 28Jul2008 2008 doi:10.2903/j.efsa.2008.139r
+Tralkoxydim 87820-88-0 single chemical entity Component is a metabolite of the substance 3-(2,4,6-trimethylphenyl)pentanedioic acid 3-(2,4,6-trimethylphenyl)pentanedioic acid Not in list C14H18O4 OC(=O)CC(CC(O)=O)c1c(C)cc(C)cc1C InChI=1/C14H18O4/c1-8-4-9(2)14(10(3)5-8)11(6-12(15)16)7-13(17)18/h4-5,11H,6-7H2,1-3H3,(H,15,16)(H,17,18) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data without Negative large colonies RMS: The United Kingdom Tralkoxydim (Addendum 1) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim 28Jul2008 2008 doi:10.2903/j.efsa.2008.139r
+Tralkoxydim 87820-88-0 single chemical entity Component is a metabolite of the substance 3-(2,4,6-trimethylphenyl)pentanedioic acid 3-(2,4,6-trimethylphenyl)pentanedioic acid Not in list C14H18O4 OC(=O)CC(CC(O)=O)c1c(C)cc(C)cc1C InChI=1/C14H18O4/c1-8-4-9(2)14(10(3)5-8)11(6-12(15)16)7-13(17)18/h4-5,11H,6-7H2,1-3H3,(H,15,16)(H,17,18) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data without Negative small colonies RMS: The United Kingdom Tralkoxydim (Addendum 1) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim 28Jul2008 2008 doi:10.2903/j.efsa.2008.139r
+Tralkoxydim 87820-88-0 single chemical entity Component is a metabolite of the substance 3-(2,4,6-trimethylphenyl)pentanedioic acid 3-(2,4,6-trimethylphenyl)pentanedioic acid Not in list C14H18O4 OC(=O)CC(CC(O)=O)c1c(C)cc(C)cc1C InChI=1/C14H18O4/c1-8-4-9(2)14(10(3)5-8)11(6-12(15)16)7-13(17)18/h4-5,11H,6-7H2,1-3H3,(H,15,16)(H,17,18) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable House mouse (as animal) lymphoma L5178Y cells Not reported no data with Negative small colonies RMS: The United Kingdom Tralkoxydim (Addendum 1) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim 28Jul2008 2008 doi:10.2903/j.efsa.2008.139r
+Tralkoxydim 87820-88-0 single chemical entity Component is a metabolite of the substance 3-(2,4,6-trimethylphenyl)pentanedioic acid 3-(2,4,6-trimethylphenyl)pentanedioic acid Not in list C14H18O4 OC(=O)CC(CC(O)=O)c1c(C)cc(C)cc1C InChI=1/C14H18O4/c1-8-4-9(2)14(10(3)5-8)11(6-12(15)16)7-13(17)18/h4-5,11H,6-7H2,1-3H3,(H,15,16)(H,17,18) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported no data without Negative RMS: The United Kingdom Tralkoxydim (Addendum 1) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim 28Jul2008 2008 doi:10.2903/j.efsa.2008.139r
+Tralkoxydim 87820-88-0 single chemical entity Component is a metabolite of the substance 3-(2,4,6-trimethylphenyl)pentanedioic acid 3-(2,4,6-trimethylphenyl)pentanedioic acid Not in list C14H18O4 OC(=O)CC(CC(O)=O)c1c(C)cc(C)cc1C InChI=1/C14H18O4/c1-8-4-9(2)14(10(3)5-8)11(6-12(15)16)7-13(17)18/h4-5,11H,6-7H2,1-3H3,(H,15,16)(H,17,18) organic compound Other Other chromosome aberration in vitro mammalian chromosome aberration test in vitro According to OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test) No Acceptable Human (as organism) lymphocytes Not reported no data with Negative RMS: The United Kingdom Tralkoxydim (Addendum 1) 2007 Conclusion on Pesticides Peer Review EFSA Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim 28Jul2008 2008 doi:10.2903/j.efsa.2008.139r
+Fenamidone 605-252-0 161326-34-7 single chemical entity Component is a metabolite of the substance (5S)-5-methyl-2-(methylthio)-5-phenyl-3,5-dihydro- 4H-imidazol-4-one (5S)-5-methyl-2-(methylsulfanyl)-5-phenyl-3,5-dihydro-4H-imidazol-4-one Not in list C11H12N2OS C[C@]1(N=C(SC)NC1=O)c2ccccc2 InChI=1/C11H12N2OS/c1-11(8-6-4-3-5-7-8)9(14)12-10(13-11)15-2/h3-7H,1-2H3,(H,12,13,14)/t11-/m0/s1 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes with Negative RMS: Czech republic - CoRMS: France Fenamidone (Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fenamidone 22Feb2016 2016 doi:10.2903/j.efsa.2016.4406
+Fenamidone 605-252-0 161326-34-7 single chemical entity Component is a metabolite of the substance (5S)-5-methyl-2-(methylthio)-5-phenyl-3,5-dihydro- 4H-imidazol-4-one (5S)-5-methyl-2-(methylsulfanyl)-5-phenyl-3,5-dihydro-4H-imidazol-4-one Not in list C11H12N2OS C[C@]1(N=C(SC)NC1=O)c2ccccc2 InChI=1/C11H12N2OS/c1-11(8-6-4-3-5-7-8)9(14)12-10(13-11)15-2/h3-7H,1-2H3,(H,12,13,14)/t11-/m0/s1 organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) lung fibroblasts (V79) Not reported yes without Negative RMS: Czech republic - CoRMS: France Fenamidone (Renewal Assessment Report) 2016 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance fenamidone 22Feb2016 2016 doi:10.2903/j.efsa.2016.4406
+Trifluralin 216-428-8 1582-09-8 single chemical entity Component is identical to the substance Trifluralin 216-428-8 1582-09-8 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline Trifluralin C13H16F3N3O4 CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 24.0000000000 h yes not applicable Negative no evidence RMS: Greece Trifluralin (Final addendum) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance trifluralin 05Aug2009 2009 doi:10.2903/j.efsa.2009.327r
+Trifluralin 216-428-8 1582-09-8 single chemical entity Component is identical to the substance Trifluralin 216-428-8 1582-09-8 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline Trifluralin C13H16F3N3O4 CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3 organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) CD-1 10 Male/Female oral: gavage 48.0000000000 h yes not applicable Negative no evidence RMS: Greece Trifluralin (Final addendum) 2005 Conclusion on Pesticides Peer Review EFSA Peer review of the pesticide risk assessment of the active substance trifluralin 05Aug2009 2009 doi:10.2903/j.efsa.2009.327r
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance methyl 3-sulfamoylthiophene-2-carboxylate methyl 3-sulfamoylthiophene-2-carboxylate Not in list C6H7NO4S2 O=S(N)(=O)c1ccsc1C(=O)OC InChI=1/C6H7NO4S2/c1-11-6(8)5-4(2-3-12-5)13(7,9)10/h2-3H,1H3,(H2,7,9,10) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle with Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance methyl 3-sulfamoylthiophene-2-carboxylate methyl 3-sulfamoylthiophene-2-carboxylate Not in list C6H7NO4S2 O=S(N)(=O)c1ccsc1C(=O)OC InChI=1/C6H7NO4S2/c1-11-6(8)5-4(2-3-12-5)13(7,9)10/h2-3H,1H3,(H2,7,9,10) organic compound Other Other gene mutation mammalian cell gene mutation assay in vitro According to OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test) No Acceptable Hamster (as animal) CHO Not reported yes, concurrent vehicle without Negative RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance methyl 3-sulfamoylthiophene-2-carboxylate methyl 3-sulfamoylthiophene-2-carboxylate Not in list C6H7NO4S2 O=S(N)(=O)c1ccsc1C(=O)OC InChI=1/C6H7NO4S2/c1-11-6(8)5-4(2-3-12-5)13(7,9)10/h2-3H,1H3,(H2,7,9,10) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Swiss 10 Male/Female oral: gavage 24.0000000000 h yes not applicable Negative no evidence RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance methyl 3-sulfamoylthiophene-2-carboxylate methyl 3-sulfamoylthiophene-2-carboxylate Not in list C6H7NO4S2 O=S(N)(=O)c1ccsc1C(=O)OC InChI=1/C6H7NO4S2/c1-11-6(8)5-4(2-3-12-5)13(7,9)10/h2-3H,1H3,(H2,7,9,10) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Swiss 10 Male/Female oral: gavage 48.0000000000 h yes not applicable Negative no evidence RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
+Thifensulfuron-methyl 616-673-4 79277-27-3 single chemical entity Component is a metabolite of the substance methyl 3-sulfamoylthiophene-2-carboxylate methyl 3-sulfamoylthiophene-2-carboxylate Not in list C6H7NO4S2 O=S(N)(=O)c1ccsc1C(=O)OC InChI=1/C6H7NO4S2/c1-11-6(8)5-4(2-3-12-5)13(7,9)10/h2-3H,1H3,(H2,7,9,10) organic compound Other Other chromosome aberration Mammalian erythrocyte micronucleus test in vivo According to OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) No Acceptable House mouse (as animal) Swiss 10 Male/Female oral: gavage 72.0000000000 h yes not applicable Negative no evidence RMS: The United Kingdom Thifensulfuron-methyl 2015 Conclusion on Pesticides Peer Review EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl 23Jul2015 2015 doi:10.2903/j.efsa.2015.4201
\ No newline at end of file diff --git a/data/efsa.csv b/data/efsa.csv index 2ea26a7..49fde00 100644 --- a/data/efsa.csv +++ b/data/efsa.csv @@ -1,105 +1,693 @@ -W, [2018-08-07T18:17:20.512100 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:17:20.512291 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:17:20.512405 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:17:20.512537 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:17:20.512637 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:17:20.512749 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:17:20.512845 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:17:20.512969 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:17:20.513074 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:17:20.513183 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:17:20.513301 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:17:20.513414 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:17:20.513512 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:17:20.513637 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:17:20.513751 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:17:20.513846 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:17:20.539332 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:17:28.716260 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:17:28.716425 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:17:28.716533 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:17:31.084855 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:17:31.085027 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:17:31.085161 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:17:31.085282 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:17:31.085405 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:17:31.085533 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:17:31.085650 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:17:31.085769 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:17:31.085891 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:17:31.086001 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:17:34.754099 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:17:34.754258 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:17:34.754420 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:17:34.754524 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:17:34.754624 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:17:34.754746 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:17:34.754851 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:17:34.754949 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:17:34.755094 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:17:34.755196 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:18:00.365181 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:18:00.365329 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:18:00.365440 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:18:00.365587 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:18:00.365685 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:18:00.365803 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:18:00.365899 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:18:00.365994 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:18:00.366124 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:18:00.366221 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:18:00.366355 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:18:00.366454 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:18:00.366549 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:18:00.366670 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:18:00.366766 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:18:00.366902 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:18:00.366999 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:18:00.367093 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:18:00.367204 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:18:00.367307 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:18:33.869299 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:18:33.869470 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:18:33.869605 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:18:33.869730 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:18:33.869840 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:18:33.869975 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:18:33.870083 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:18:33.870185 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:18:33.870300 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:18:33.870423 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:18:50.410992 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:18:50.411139 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:18:50.411247 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:18:50.411392 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:18:50.411491 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:18:50.411588 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:18:50.411706 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:18:50.411823 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:18:50.411952 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:18:50.412049 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:18:50.531094 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:18:50.531282 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:18:53.918928 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:18:53.919093 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:18:53.919221 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:18:53.919348 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:18:53.919446 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:18:53.919578 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:18:53.919675 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:18:53.919781 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:19:09.724564 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:19:09.724723 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:19:09.724862 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:19:09.724982 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:19:09.725127 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:19:09.725247 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:19:09.725364 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:19:09.725486 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:19:09.725597 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:19:09.725713 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:19:09.725847 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:19:09.725963 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:19:09.726069 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:19:09.726188 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. -W, [2018-08-07T18:19:09.726306 #15266] WARN -- : SMILES parsing failed for ''', this may be caused by an incorrect SMILES string. +c1ccc(cc1)CNc1ncnc2c1[nH]cn2,0 +OS(=O)(=O)O.Oc1cccc2c1nccc2.Oc1cccc2c1nccc2,1 +Oc1cccc2c1nccc2,1 +CO[C@H]1C[C@H](O[C@H]2[C@@H](C)/C=C/C=C/3\CO[C@H]4[C@]3(O)[C@@H](C=C([C@H]4O)C)C(=O)O[C@H]3C[C@@H](C/C=C/2\C)O[C@]2(C3)C=C[C@@H]([C@H](O2)[C@H](CC)C)C)O[C@H]([C@@H]1O[C@H]1C[C@H](OC)[C@H]([C@@H](O1)C)O)C,0 +N#C[C@H](c1cccc(c1)Oc1ccccc1)OC(=O)[C@@H]1[C@@H](C1(C)C)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F,0 +Clc1cc(N)c(c(n1)C(=O)O)Cl,0 +COc1nc(nc(c1)O)NC(=O)NS(=O)(=O)c1n(C)ncc1c1nnn(n1)C,0 +COc1cc(OC)nc(n1)N,0 +Cn1nnc(n1)c1cnn(c1S(=O)(=O)N)C,0 +Clc1ccc(c(c1)Cl)O,0 +OC(=O)CCCOc1ccc(cc1Cl)Cl,0 +O=C1NS(=O)(=O)Cc2c1cccc2,0 +COc1cc(OC)nc(n1)NC(=O)NS(=O)(=O)Cc1ccccc1C(=O)O,0 +COC(=O)c1ccccc1CS(=O)(=O)N,0 +CC(N1C(=O)c2ccccc2NS1(=O)=O)C,0 +CC(OC(=O)N[C@@H](C(=O)N[C@@H](c1nc2c(s1)cc(cc2)F)C)C(C)C)C,1 +OC(C(C)(C)C)C(n1cncn1)Oc1ccc(cc1)c1ccccc1,0 +Fc1ccc(c(c1)c1ccc(c(c1)Cl)Cl)NC(=O)c1cn(nc1C(F)F)C,0 +Brc1ccc(cc1)c1ccc(cc1)C(CC(c1c(=O)oc2c(c1O)cccc2)c1ccccc1)O,0 +BrC1COC(C1)(Cn1cncn1)c1ccc(cc1Cl)Cl,0 +CCCCc1c(C)nc(nc1OS(=O)(=O)N(C)C)NCC,0 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0000000..5da45c4 --- /dev/null +++ b/data/merged.csv @@ -0,0 +1,8301 @@ +SMILES,Activity +Br/C(=C\c1ccccc1)/[N+](=O)[O-],1 +Br/C=C(/c1ccc(cc1Cl)Cl)\OP(=O)(OC)OC,0 +Br/C=C(\c1ccc(cc1Cl)Cl)/OP(=O)(OC)OC,0 +Br/C=C/Br,1 +Br/C=C/c1cn(C2CC(C(O2)CO)O)c(=O)[nH]c1=O,0 +Br/C=C/c1cn([C@H]2C[C@@H]([C@H](O2)CO)O)c(=O)[nH]c1=O,0 +BrC(=C)C(=O)C,1 +BrC(=C)C(=O)O,0 +BrC(=C)C=O,1 +BrC(Br)Br,1 +BrC(C#N)Br,1 +BrC(C(=O)O)Br,1 +BrC(C(Br)(Br)Br)Br,0 +BrC(C(Br)(C)C)COP(=O)(OCC(C(Br)(C)C)Br)OCC(C(Br)(C)C)Br,0 +BrC(C(Br)Br)Br,0 +BrC(C(Br)C)COP(=O)(OCC(C(Br)C)Br)OCC(C(Br)C)Br,1 +BrC(C(C)(C)C)C(=O)Nc1ccccc1,0 +BrC(C1=C(Br)C(=O)OC1)Br,1 +BrC(C1=C(Br)C(=O)OC1O)Br,1 +BrC(C1=C(Cl)C(=O)OC1)Br,1 +BrC(C1=C(Cl)C(=O)OC1O)Br,1 +BrC(C=O)CBr,1 +BrC([N+](=O)[O-])(Br)Br,1 +BrC(c1ccccc1)C(=O)NCc1ccccc1,0 +BrC/C=C\CBr,1 +BrC1=C(Br)C(=O)OC1,1 +BrC1C(Cl)C(Br)C(C(C1Br)Br)Br,0 +BrC1COC(C1)(Cn1cncn1)c1ccc(cc1Cl)Cl,0 +BrC=C,1 +BrCBr,1 +BrCC#C,1 +BrCC#N,0 +BrCC(=C)Br,1 +BrCC(=O)N(Cc1ccccc1)C,0 +BrCC(=O)NCc1ccccc1,1 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+C[N+](=C1C=CC(=C(c2ccc(cc2)N(C)C)c2ccccc2)C=C1)C,0 +C[N+](CC1OC1)(C)C,1 +C[N+](Cc1ccccc1)(C)C,0 +C[N+](Cc1ccccc1)(C)C.Cl,0 +C[N+]1(C)CCCCC1.[Cl-],0 +C[N+]1(C)CCOCC1,0 +C[N+]1(C)CCOCC1.Cl,0 +C[N+]1=CC=C(CC1)c1ccccc1,1 +C[Si](N=N#N)(C)C,1 +C[Si](N[Si](C)(C)C)(C)C,0 +C[Si](O)(C)C,0 +C[Si](O[Si](C)(C)C)(C)C,0 +C[Si](O[Si](C)(C)C)(O[Si](C)(C)C)C,0 +C[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C,0 +C[Si](c1ccc(cc1)[Si](CCCOCC1OC1)(C)C)(CCCOCC1OC1)C,1 +C[n+]1c2ccccc2c(c2c1cccc2)N,1 +C[n+]1c2ccccc2c(c2c1cccc2)N.Cl,1 +C[n+]1c2ccccc2cc2c1cccc2,1 +C[n+]1c2ccccc2cc2c1cccc2.Cl,1 +C[n+]1c2ccccc2cc2c1cccc2N,1 +C[n+]1c2ccccc2cc2c1cccc2N.Cl,1 +C[n+]1c2ccccc2nc2c1cccc2,1 +C[n+]1c2ccccc2nc2c1cccc2.COS(=O)(=O)O,1 +C[n+]1ccc(cc1)c1cc[n+](cc1)C,0 +C[n+]1ccc(cc1)c1ccccc1,0 +C[n+]1cccc(c1)C(=O)O,0 +C[n+]1cccc(c1)OC(=O)N(C)C,0 +C[n+]1cccc(c1)OC(=O)N(C)C.Br,0 +C[n+]1cccc2c1C=C[C@@H]1[C@H]2O1,1 +C[n+]1ccsc1/N=N/c1c(c2ccccc2)n(c2c1cccc2)C.Cl,1 +C[n+]1ccsc1N=Nc1c(c2ccccc2)n(c2c1cccc2)C,1 +Cc1c(Br)c2c(n1S(=O)(=O)C1=NN=C[N]1)cc(cc2)F,0 +Cc1c(C)c(Br)c(c(c1Br)Br)Br,0 +Cc1c(C)c([N+](=O)[O-])c(c(c1C)[N+](=O)[O-])C(C)(C)C,0 +Cc1c(C)c2ccccc2c2c1c(Cl)c1ccccc1n2,1 +Cc1c(C)c2ccccc2c2c1c(N)c1ccccc1n2,1 +Cc1c(C)c2nccnc2c2c1n(C)c(n2)N,1 +Cc1c(C)ccc(c1C)C,0 +Cc1c(C)cccc1C,1 +Cc1c(C)cccc1N,1 +Cc1c(C)cccc1N=Nc1c(O)ccc2c1cccc2,0 +Cc1c(C)cccc1O,0 +Cc1c(N)c(C)c(c(c1C)N)C,0 +Cc1c(N)ccc(c1C)N,0 +Cc1c(N)cccc1Cl,0 +Cc1c(N)cccc1N=Nc1cccc(c1C)N,1 +Cc1c(N)cccc1N=[N+](c1cccc(c1C)N)[O-],1 +Cc1c(NC)ccc2c1nccn2,1 +Cc1c(ccc(c1C1=NOCC1)S(=O)(=O)C)C(=O)c1c[nH]n(c1=O)C,1 +Cc1c(cccc1[N+](=O)[O-])[N+](=O)[O-],1 +Cc1c2C3NC3c3c(-c2c(c2c1cccc2)C)cccc3,1 +Cc1c2C3OC3c3c(-c2c(c2c1cccc2)C)cccc3,1 +Cc1c2C3OC3c3c(-c2cc2c1cccc2)cccc3,1 +Cc1c2[C@H]3N[C@H]3c3c(-c2cc2c1cccc2)cccc3,1 +Cc1c2[C@H]3O[C@H]3c3c(-c2c(c2c1cccc2)C)cccc3,1 +Cc1c2[C@H]3O[C@H]3c3c(-c2cc2c1cccc2)cccc3,1 +Cc1c2cc(C)c(cc2c(c2c1cccc2)C)C,1 +Cc1c2cc(C)c3c(c2nc2c1cccc2)cccc3,1 +Cc1c2ccc3c(c2c(c2c1cccc2)C)cccc3,1 +Cc1c2ccc3c(c2cc2c1cccc2)cccc3,1 +Cc1c2ccc3c(c2nc2c1cccc2)cccc3,1 +Cc1c2cccc(c2nc2c1ccc1c2cccc1)C,1 +Cc1c2ccccc2c(c2-c3c4c(-c12)cccc4ccc3)C,1 +Cc1c2ccccc2c(c2c1c1ccccc1cc2)COS(=O)(=O)O,1 +Cc1c2ccccc2c(c2c1cccc2)C,1 +Cc1c2ccccc2c(c2c1cccc2)COS(=O)(=O)O,1 +Cc1c2ccccc2c(c2c1cccc2)[C@@H]1CO1,1 +Cc1c2ccccc2c2c3c1ccc1c3c(cc2)ccc1,1 +Cc1c2ccccc2cc2c1c1ccccc1cc2,1 +Cc1c2ccccc2cc2c1cccc2,1 +Cc1c2cnccc2c(c2c1c1ccccc1[nH]2)C,1 +Cc1c[nH]c(=S)[nH]c1=O,0 +Cc1c[nH]cn1,0 +Cc1cc(=O)[nH]c(=S)[nH]1,0 +Cc1cc(=O)[nH]o1,0 +Cc1cc(C)c(c(c1)C)C,0 +Cc1cc(C)c(c(c1)C)CN1C2C1c1ccccc1-c1c2cccc1,1 +Cc1cc(C)c(c(c1)C)N,1 +Cc1cc(C)c(c(c1N)C)N,1 +Cc1cc(C)c(cc1/N=N/c1cc(c2c(c1O)cccc2)S(=O)(=O)O)S(=O)(=O)O.[Na+].[Na+],0 +Cc1cc(C)c(cc1C)C,0 +Cc1cc(C)c(cc1N=Nc1cc(c2c(c1O)cccc2)S(=O)(=O)O)S(=O)(=O)O,0 +Cc1cc(C)c(cc1[N+](=O)[O-])[N+](=O)[O-],1 +Cc1cc(C)c2c(c1)c(C)c1c(n2)c2ccccc2cc1,1 +Cc1cc(C)c2c(c1)c1ccccc1cc2,1 +Cc1cc(C)c2c(c1)ccc1c2cccc1,1 +Cc1cc(C)c2c(c1N)nsn2,1 +Cc1cc(C)c2c(n1)cc(c(c2)C)N,1 +Cc1cc(C)cc(c1)/N=N/c1c(O)ccc2c1cccc2,0 +Cc1cc(C)cc(c1)C(=O)N(C(C)(C)C)NC(=O)c1ccc(cc1)C(=O)C,0 +Cc1cc(C)cc(c1)C(=O)N(C(C)(C)C)NC(=O)c1ccc(cc1)C(O)C,0 +Cc1cc(C)cc(c1)C(=O)N(C(C)(C)C)NC(=O)c1ccc2c(c1C)C(O)CCO2,0 +Cc1cc(C)cc(c1)C(=O)N(C(C)(C)C)NC(=O)c1ccc2c(c1C)CCCO2,0 +Cc1cc(C)cc(c1)C,0 +Cc1cc(C)cc(c1)N,1 +Cc1cc(C)cc(c1)N=Nc1c(O)ccc2c1cccc2,0 +Cc1cc(C)cc(c1)O,0 +Cc1cc(C)nc(n1)N,0 +Cc1cc(C)nc(n1)Nc1ccccc1,0 +Cc1cc(Cc2cc(C)cc(c2O)C(C)(C)C)c(c(c1)C(C)(C)C)O,0 +Cc1cc(N)c(cc1C)C,1 +Cc1cc(N)c(cc1Cl)S(=O)(=O)O,0 +Cc1cc(N)c(cc1N)C,1 +Cc1cc(N)cc(c1)N,0 +Cc1cc(O)c(c(=O)o1)C(=O)C,0 +Cc1cc(O)c(c(=O)o1)C(=O)C.[Na+],0 +Cc1cc(O)c(cc1C1(OS(=O)(=O)c2c1cccc2)c1cc(C)c(cc1C)O)C,0 +Cc1cc(O)c2c(c1)C(=O)C(=CC2=O)c1c(C)cc2c(c1O)C(=O)C=CC2=O,0 +Cc1cc(O)c2c(c1)C(=O)C13C4(C2=O)C(=O)C2C(C1C1C(C3C(=O)C34C(=O)c4c(O)cc(cc4C(=O)C213)C)C)C,0 +Cc1cc(O)c2c(c1)C(=O)[C@]13C(=C(O)[C@H]4[C@H]([C@@H]3[C@H]3[C@@H]([C@@H]1C(=C1[C@@]43C(=O)c3c(C1=O)c(O)cc(c3)C)O)O)O)C2=O,0 +Cc1cc(O)c2c(c1)C(=O)c1c(C2=O)c(O)c(c(c1)O)O,0 +Cc1cc(O)c2c(c1)C(=O)c1c(C2=O)c(O)cc(c1)O,1 +Cc1cc(O)c2c(c1)C(=O)c1c(C2=O)c(O)cc(c1O)O,1 +Cc1cc(O)c2c(c1)C(=O)c1c(C2=O)c(O)cc(c1c1c(O)cc(c2c1C(=O)c1cc(C)cc(c1C2=O)O)O)O,0 +Cc1cc(O)c2c(c1)C(=O)c1c(C2=O)c(O)ccc1,1 +Cc1cc(O)c2c(c1O)C(=O)c1c(C2=O)c(O)ccc1O,1 +Cc1cc(O)nc(n1)S,0 +Cc1cc([N+](=O)[O-])c(c2c1[nH]c1c2cccc1)C,1 +Cc1cc([N+](=O)[O-])c(c2c1n(C)c1c2cccc1)C,1 +Cc1cc(c(c(c1)C(C)(C)C)O)C(C)(C)C,0 +Cc1cc(c(c(c1)C(C)(C)C)O)C(c1ncc(n1C)[N+](=O)[O-])O,0 +Cc1cc(cc(c1)C(=O)O)C(=O)N(C(C)(C)C)NC(=O)c1ccc2c(c1C)C(O)CCO2,0 +Cc1cc(cc(c1)C)[N+](=O)[O-],1 +Cc1cc(cc(c1N)C)c1cc(C)c(c(c1)C)N,0 +Cc1cc(ccc1/N=N/c1c(O)c2c(N)cc(cc2cc1S(=O)(=O)O)S(=O)(=O)O)c1ccc(c(c1)C)/N=N/c1c(O)c2c(N)cc(cc2cc1S(=O)(=O)O)S(=O)(=O)O,1 +Cc1cc(ccc1/N=N/c1c(O)c2c(O)cc(cc2cc1S(=O)(=O)O)S(=O)(=O)O)c1ccc(c(c1)C)/N=N/c1c(O)c2c(O)cc(cc2cc1S(=O)(=O)O)S(=O)(=O)O,0 +Cc1cc(ccc1/N=N/c1c(O)ccc2c1cccc2)/N=N/c1ccccc1C,1 +Cc1cc(ccc1/N=N/c1ccc(c(c1)C(=O)O)O)c1ccc(c(c1)C)/N=N/c1c(N)c(C)cc(c1N)S(=O)(=O)O.[Na+].[Na+],1 +Cc1cc(ccc1/N=N/c1ccc2c(c1O)c(N)c(cc2S(=O)(=O)O)S(=O)(=O)O)c1ccc(c(c1)C)/N=N/c1ccc2c(c1O)c(N)c(cc2S(=O)(=O)O)S(=O)(=O)O,1 +Cc1cc(ccc1/N=N/c1ccccc1)N(C)C,1 +Cc1cc(ccc1C)N=Nc1c(O)ccc2c1cccc2,0 +Cc1cc(ccc1N)/N=N/c1ccccc1C,1 +Cc1cc(ccc1N)/N=N/c1ccccc1C.Cl,1 +Cc1cc(ccc1N)N=Nc1ccccc1C,1 +Cc1cc(ccc1N)c1ccccc1C,1 +Cc1cc(ccc1N=Nc1c(O)c2c(N)cc(cc2cc1S(=O)(=O)O)S(=O)(=O)O)c1ccc(c(c1)C)N=Nc1c(O)c2c(N)cc(cc2cc1S(=O)(=O)O)S(=O)(=O)O,1 +Cc1cc(ccc1N=Nc1c(O)c2c(O)cc(cc2cc1S(=O)(=O)O)S(=O)(=O)O)c1ccc(c(c1)C)N=Nc1c(O)c2c(O)cc(cc2cc1S(=O)(=O)O)S(=O)(=O)O,0 +Cc1cc(ccc1N=Nc1c(O)ccc2c1cccc2)N=Nc1ccccc1C,1 +Cc1cc(ccc1N=Nc1cc(c2c(c1N)cccc2)S(=O)(=O)O)c1ccc(c(c1)C)N=Nc1cc(c2c(c1N)cccc2)S(=O)(=O)O,0 +Cc1cc(ccc1N=Nc1ccc(c(c1)C(=O)O)O)c1ccc(c(c1)C)N=Nc1c(N)c(C)cc(c1N)S(=O)(=O)O,1 +Cc1cc(ccc1N=Nc1ccc2c(c1O)c(N)c(cc2S(=O)(=O)O)S(=O)(=O)O)c1ccc(c(c1)C)N=Nc1ccc2c(c1O)c(N)c(cc2S(=O)(=O)O)S(=O)(=O)O,1 +Cc1cc(ccc1N=Nc1ccccc1)N(C)C,1 +Cc1cc(nc(n1)N)C1CC1,0 +Cc1cc(nc(n1)O)C1CC1,0 +Cc1cc2-c3ccccc3Cc2cc1C,0 +Cc1cc2CCCc2c2c1c1ccccc1cc2,0 +Cc1cc2[nH]c3c(c2c2c1cccc2)c1ccccc1c(c3)C,1 +Cc1cc2c(C)cccc2c2c1c1ccccc1cc2,1 +Cc1cc2c(NC(=O)CCl)snc2cc1,1 +Cc1cc2c(O)cccc2c2c1cc1ccccc1c2,1 +Cc1cc2c(c3c1cccc3)ccc1c2cccc1,1 +Cc1cc2c(c3c1nc(cn3)c1ccccc1)nc(n2C)N,1 +Cc1cc2c(c3c1ncc(n3)c1ccccc1)nc(n2C)N,1 +Cc1cc2c(cc1C)nc1c(c2C)ccc2c1cccc2,1 +Cc1cc2c(nc1N)[nH]c1c2cccc1,1 +Cc1cc2c3c4c1cccc4ccc3cc1c2cccc1,1 +Cc1cc2cc3cccc(c3c(c2c(c1)O)O)O,1 +Cc1cc2cc3ccccc3c3c2c2c1cccc2cc3,1 +Cc1cc2cc3ccccc3cc2c2c1cccc2,1 +Cc1cc2ccc3c4c2c(c1)ccc4cc1c3cccc1,1 +Cc1cc2cccc3-c4c(-c(c1)c23)cc1ccccc1c4,1 +Cc1cc2cccc3c2c2c1c1ccccc1cc2cc3,1 +Cc1cc2cccc3c2c2c1cc1ccccc1c2cc3,1 +Cc1cc2ccccc2c(c1)C,0 +Cc1cc2ccccc2c(c1)[N+](=O)[O-],1 +Cc1cc2ccccc2c2c1c1ccccc1c(c2)[N+](=O)[O-],1 +Cc1cc2ccccc2c2c1c1ccccc1cc2,1 +Cc1cc2ccccc2c2c1cc1ccccc1c2,1 +Cc1cc2cccnc2c(c1)C(=O)O,0 +Cc1cc2n(C)c(nc2c2c1nccn2)N,1 +Cc1cc2nc3-c(n(c2cc1C)C)nc(=O)[nH]c3=O,1 +Cc1cc2ncccc2c2c1n(C)c(n2)N,1 +Cc1cc2ncccc2c2c1n(C)cn2,0 +Cc1ccc(c(c1)C(=O)O)/N=C/c1cccc2c1nccc2,0 +Cc1ccc(c(c1)C(=O)O)[N+](=O)[O-],1 +Cc1ccc(c(c1)C)/N=C/N=C/N(c1ccc(cc1C)C)C,0 +Cc1ccc(c(c1)C)/N=N/c1c(O)ccc2c1cccc2,1 +Cc1ccc(c(c1)C)/N=N/c1c2ccc(cc2cc(c1O)S(=O)(=O)O)S(=O)(=O)O,1 +Cc1ccc(c(c1)C)C,0 +Cc1ccc(c(c1)C)N,1 +Cc1ccc(c(c1)C)N=Nc1c(O)ccc2c1cccc2,1 +Cc1ccc(c(c1)C)N=Nc1c2ccc(cc2cc(c1O)S(=O)(=O)O)S(=O)(=O)O,1 +Cc1ccc(c(c1)C)NC(=O)C(C(=O)C)N=Nc1ccc(cc1Cl)c1ccc(c(c1)Cl)N=NC(C(=O)Nc1ccc(cc1C)C)C(=O)C,0 +Cc1ccc(c(c1)C)O,1 +Cc1ccc(c(c1)C)OP(=O)(Oc1ccc(cc1C)C)Oc1ccc(cc1C)C,0 +Cc1ccc(c(c1)C)[N+](=O)[O-],1 +Cc1ccc(c(c1)N)C,1 +Cc1ccc(c(c1)N)N,1 +Cc1ccc(c(c1)N)O,1 +Cc1ccc(c(c1)N)[N+](=O)[O-],0 +Cc1ccc(c(c1)O)C(C)C,0 +Cc1ccc(c(c1)O)C,0 +Cc1ccc(c(c1)O)N,1 +Cc1ccc(c(c1)O)NS(=O)(=O)N(C)C,0 +Cc1ccc(c(c1)O)O,0 +Cc1ccc(c(c1)S(=O)(=O)O)/N=N/c1c(O)c(cc2c1cccc2)C(=O)O.[Na+].[Na+],0 +Cc1ccc(c(c1)S(=O)(=O)O)N,0 +Cc1ccc(c(c1)S(=O)(=O)O)N=Nc1c(O)c(cc2c1cccc2)C(=O)O,0 +Cc1ccc(c(c1)S(=O)(=O)O)N=Nc1c(O)ccc2c1cccc2,0 +Cc1ccc(c(c1)S(=O)(=O)O)Nc1ccc(c2c1C(=O)c1ccccc1C2=O)N,1 +Cc1ccc(c(c1)[N+](=O)[O-])/N=N/c1c(O)ccc2c1cccc2,1 +Cc1ccc(c(c1)[N+](=O)[O-])C,1 +Cc1ccc(c(c1)[N+](=O)[O-])N,1 +Cc1ccc(c(c1)[N+](=O)[O-])N=Nc1c(O)ccc2c1cccc2,1 +Cc1ccc(c(c1)[N+](=O)[O-])[N+](=O)[O-],1 +Cc1ccc(c(c1C(c1ncc(n1C)[N+](=O)[O-])O)O)C(C)(C)C,0 +Cc1ccc(c(c1O)C)C,0 +Cc1ccc(c2c1c1ccccc1[nH]2)C,1 +Cc1ccc(c2c1ccc1c2cccc1)C,1 +Cc1ccc(c2c1cccc2)C,0 +Cc1ccc(c2c1n(C)c1c2cccc1)C,1 +Cc1ccc(cc1)/C(=C\CN1CCCC1)/c1ccccn1,0 +Cc1ccc(cc1)/C=C/c1ccc(cc1)N,1 +Cc1ccc(cc1)/C=C/c1ccc(cc1)[N+](=O)[O-],1 +Cc1ccc(cc1)/N=N/N(C)C,1 +Cc1ccc(cc1)/N=N/NCc1ccc(cc1)[N+](=O)[O-],1 +Cc1ccc(cc1)/N=N/NCc1ccccc1,1 +Cc1ccc(cc1)/N=N/c1c(O)ccc2c1cccc2,0 +Cc1ccc(cc1)Br,0 +Cc1ccc(cc1)C(=O)ON(C(=O)c1ccccc1)OCc1ccccc1,1 +Cc1ccc(cc1)C(=O)c1cc(O)c(c(c1)[N+](=O)[O-])O,0 +Cc1ccc(cc1)C(=O)n1ncc(c(c1=O)Cl)Cl,0 +Cc1ccc(cc1)C(C)(C)C,0 +Cc1ccc(cc1)C(N)C,0 +Cc1ccc(cc1)C(O)(C)C,0 +Cc1ccc(cc1)C,0 +Cc1ccc(cc1)CC1OC1,1 +Cc1ccc(cc1)CC[C@@H]1OC1,1 +Cc1ccc(cc1)CN1C2C1c1ccccc1-c1c2cccc1,1 +Cc1ccc(cc1)COS(=O)(=O)c1ccc(cc1)C,0 +Cc1ccc(cc1)C[C@@H]1OC1,1 +Cc1ccc(cc1)Cc1ccccc1,0 +Cc1ccc(cc1)Cl,0 +Cc1ccc(cc1)N(C(=O)C)O,0 +Cc1ccc(cc1)N(C)C,1 +Cc1ccc(cc1)N(S(=O)(=O)N(C)C)SC(Cl)(Cl)F,0 +Cc1ccc(cc1)N=NN(C)C,1 +Cc1ccc(cc1)N=Nc1c(O)ccc2c1cccc2,0 +Cc1ccc(cc1)NC(=O)c1csc(c1)[N+](=O)[O-],1 +Cc1ccc(cc1)NN=NCc1ccc(cc1)[N+](=O)[O-],1 +Cc1ccc(cc1)NN=NCc1ccccc1,1 +Cc1ccc(cc1)NS(=O)(=O)c1cccc2c1nccc2,0 +Cc1ccc(cc1)Nc1ccc(c2c1C(=O)c1ccccc1C2=O)O,0 +Cc1ccc(cc1)Nc1ccc(cc1)[N+](=O)[O-],1 +Cc1ccc(cc1)O,0 +Cc1ccc(cc1)OC[C@@H]1OC1,1 +Cc1ccc(cc1)OP(=O)(Oc1cccc(c1)C)Oc1cccc(c1)C,0 +Cc1ccc(cc1)S(=O)(=O)N1C2C1c1ccccc1-c1c2cccc1,1 +Cc1ccc(cc1)S(=O)(=O)N1[C@@H]2[C@H]1c1ccccc1-c1c2cccc1,1 +Cc1ccc(cc1)S(=O)(=O)NC1CCCCC1,0 +Cc1ccc(cc1)S(=O)(=O)O.CCOC[C@H](COc1ccc(cc1)NC(=O)CC[S+](C)C)O,0 +Cc1ccc(cc1)S(=O)(=O)OCC1OC1,1 +Cc1ccc(cc1)S(=O)(=O)OC[C@@H]1OC1,1 +Cc1ccc(cc1)S(=O)(=O)OCc1ccc(cc1)[N+](=O)[O-],1 +Cc1ccc(cc1)S(=O)(=O)OCc1ccccc1,0 +Cc1ccc(cc1)S(=O)(=O)n1ncc(c(c1=O)Cl)Cl,0 +Cc1ccc(cc1)[C@H]1OC1,1 +Cc1ccc(cc1)[N+]#N,1 +Cc1ccc(cc1)[N+](=O)[O-],0 +Cc1ccc(cc1)c1[nH]c(nc1c1ccc(cc1)C)c1ccc(cc1C)C,1 +Cc1ccc(cc1)c1nc2c(o1)cccc2,0 +Cc1ccc(cc1)c1nc2n(c1[N+](=O)[O-])CCS2,1 +Cc1ccc(cc1/N=[N+](/c1cc(ccc1C)[N+](=O)[O-])\[O-])[N+](=O)[O-],0 +Cc1ccc(cc1C)S(=O)(=O)O,0 +Cc1ccc(cc1C)S(=O)(=O)O.[Na+],0 +Cc1ccc(cc1N)/N=N/c1ccc(c(c1)N)C,1 +Cc1ccc(cc1N)N=Nc1ccc(c(c1)N)C,1 +Cc1ccc(cc1N=Nc1cc(N)ccc1C)N,1 +Cc1ccc(cc1N=[N+](c1cc(ccc1C)[N+](=O)[O-])[O-])[N+](=O)[O-],0 +Cc1ccc(cc1NCC)O,1 +Cc1ccc(o1)C,0 +Cc1ccc(o1)C=O,0 +Cc1ccc2-c3c(C(c2c1)C)cc(cc3)C,0 +Cc1ccc2-c3c(Cc2c1)cc(cc3)C,0 +Cc1ccc2-c3c([C@H](c2c1)C)cccc3,1 +Cc1ccc2-c3c4c(-c2c1)cc1ccccc1c4cc1c3cccc1,1 +Cc1ccc2c(-c3ccccc3C2C)c1,1 +Cc1ccc2c(-c3ccccc3[C@H]2C)c1,1 +Cc1ccc2c(c1)C(=O)c1c(C2=O)cccc1,0 +Cc1ccc2c(c1)C(C)C1C(=Nc3c1cccc3)N2C,1 +Cc1ccc2c(c1)C1C(=N2)N(C)c2c(C1C)cccc2,1 +Cc1ccc2c(c1)C1C(C)c3cc(C)ccc3N(C1=N2)C,1 +Cc1ccc2c(c1)c(C)c1c(-c3ccccc3C(C1O)O)n2,0 +Cc1ccc2c(c1)c(C)c1c(c2)cccc1,1 +Cc1ccc2c(c1)c(C)c1c(c2C)cccc1,1 +Cc1ccc2c(c1)c(C)c1c(n2)c2ccccc2cc1,1 +Cc1ccc2c(c1)c(N)c1c(n2)cccc1,1 +Cc1ccc2c(c1)c(N)sn2,1 +Cc1ccc2c(c1)c(ccc2)[N+](=O)[O-],1 +Cc1ccc2c(c1)c1c(C)ccc(c1[nH]2)C,1 +Cc1ccc2c(c1)c1cc(C)ccc1cc2,1 +Cc1ccc2c(c1)c1cc3ccccc3cc1cc2,1 +Cc1ccc2c(c1)c1ccc3c(c1cc2)ccc1c3cccc1C,0 +Cc1ccc2c(c1)c1ccc3c(c1cc2)cccc3,1 +Cc1ccc2c(c1)c1ccc3c4c1c(c2)ccc4ccc3,1 +Cc1ccc2c(c1)cc(cc2)[N+](=O)[O-],1 +Cc1ccc2c(c1)cc1-c3cccc4c3c(-c1n2)ccc4,0 +Cc1ccc2c(c1)cc1c(c2)c2ccccc2cc1,1 +Cc1ccc2c(c1)cc1c(c2)ccc2c1cccc2,1 +Cc1ccc2c(c1)cc1c(c2)cccc1,1 +Cc1ccc2c(c1)cc1c(n2)c2ccccc2cc1,1 +Cc1ccc2c(c1)cc1c3c2ccc2c3c(cc1)ccc2,1 +Cc1ccc2c(c1)ccc(=O)o2,0 +Cc1ccc2c(c1)ccc(c2)[N+](=O)[O-],1 +Cc1ccc2c(c1)ccc1c2c2c([nH]1)ccc1c2cccc1,1 +Cc1ccc2c(c1)ccc1c2cc2ccccc2c1,1 +Cc1ccc2c(c1)ccc1c2ccc2c1cccc2,1 +Cc1ccc2c(c1)ccc1c2cccc1,1 +Cc1ccc2c(c1)cccc2,0 +Cc1ccc2c(c1)cccc2C,0 +Cc1ccc2c(c1)cccc2[N+](=O)[O-],1 +Cc1ccc2c(c1)cccn2,1 +Cc1ccc2c(c1)nc([nH]2)N,1 +Cc1ccc2c(c1)nc(n2C)N,1 +Cc1ccc2c(c1)nc1-c3ccccc3C(C(c1c2C)O)O,0 +Cc1ccc2c(c1)nc1c(c2)ccc2c1cccc2,1 +Cc1ccc2c(c1)nc1c(c2C)ccc2c1cccc2,1 +Cc1ccc2c(c1)nccc2,1 +Cc1ccc2c(c1)nn[nH]2,0 +Cc1ccc2c(c1C)c1ccccc1cc2,0 +Cc1ccc2c(c1C)cccc2,0 +Cc1ccc2c(c1Nc1ccccc1)C(=O)c1c(C2=O)cccc1,1 +Cc1ccc2c(c1O)NC(O)C1N(C2=O)C=C(C1)/C=C/C(=O)N,1 +Cc1ccc2c(n1)cccc2,1 +Cc1ccc2c3c1CC(c3c1c(c2)c2ccccc2cc1)OS(=O)(=O)O,1 +Cc1ccc2c3c1CCc3c1c(-c3ccccc3C3C1N3)c2,1 +Cc1ccc2c3c1CCc3c1c(-c3ccccc3C3C1O3)c2,1 +Cc1ccc2c3c1CCc3c1c(-c3ccccc3[C@H]3[C@@H]1N3)c2,1 +Cc1ccc2c3c1CCc3c1c(-c3ccccc3[C@H]3[C@@H]1O3)c2,1 +Cc1ccc2c3c1CCc3c1c(c2)c2ccccc2cc1,1 +Cc1ccc2c3c1ccc1c3c(C2)ccc1,1 +Cc1ccc2c3c1ccc1c3c(c2=O)ccc1,1 +Cc1ccc2c3c1ccc1c3c(cc2)c2c(c1)cccc2,1 +Cc1ccc2c3c1ccc1c3c(cc2)cc2c1cccc2,1 +Cc1ccc2c3c1ccc1c3c(cc2)ccc1,1 +Cc1cccc(c1)/N=N/c1ccc(cc1)N(C)C,1 +Cc1cccc(c1)Br,0 +Cc1cccc(c1)C(=O)Cl,1 +Cc1cccc(c1)C(=O)O,0 +Cc1cccc(c1)C,0 +Cc1cccc(c1)N,0 +Cc1cccc(c1)N.Cl,0 +Cc1cccc(c1)N=Nc1ccc(cc1)N(C)C,1 +Cc1cccc(c1)NC(=O)c1csc(c1)[N+](=O)[O-],1 +Cc1cccc(c1)NS(=O)(=O)c1cccc2c1nccc2,0 +Cc1cccc(c1)O,0 +Cc1cccc(c1)OP(=O)(Oc1cccc(c1)C)Oc1cccc(c1)C,0 +Cc1cccc(c1)OP(=O)(Oc1ccccc1)Oc1ccccc1,0 +Cc1cccc(c1)[N+](=O)[O-],0 +Cc1cccc(c1)c1nc2c(o1)cccc2,0 +Cc1cccc(c1N)C,0 +Cc1cccc(c1N)C,1 +Cc1cccc(c1N=Nc1c(O)ccc2c1cccc2)C,0 +Cc1cccc(c1O)C,0 +Cc1cccc2-c3c(C(c12)C)cccc3,1 +Cc1cccc2-c3c([C@H](c12)C)cccc3,1 +Cc1cccc2c1-c1cc3ccccc3cc1C1C2N1,1 +Cc1cccc2c1-c1cc3ccccc3cc1C1C2O1,1 +Cc1cccc2c1-c1ccccc1C2C,1 +Cc1cccc2c1-c1ccccc1[C@@H]2C,1 +Cc1cccc2c1N(C)C1=Nc3c(C1C2C)cccc3,1 +Cc1cccc2c1c1cc3ccccc3cc1cc2,1 +Cc1cccc2c1c1ccc3c(c1cc2)cccc3,1 +Cc1cccc2c1c1ccc3c4c1c(c2)ccc4ccc3,1 +Cc1cccc2c1cc1c(c2)ccc2c1cccc2,1 +Cc1cccc2c1cc1ccc3c(c1c2)cccc3,1 +Cc1cccc2c1cc1ccc3c(c1n2)cccc3,1 +Cc1cccc2c1cc1ccc3c4c1c2ccc4ccc3,1 +Cc1cccc2c1cc1ccccc1c2,0 +Cc1cccc2c1ccc1c2cc2c(c1)cccc2,1 +Cc1cccc2c1ccc1c2ccc2c1cccc2,1 +Cc1cccc2c1ccc1c2cccc1,1 +Cc1cccc2c1cccc2,0 +Cc1cccc2c1cccn2,1 +Cc1cccc2c1nc1c(c2)ccc2c1cccc2,0 +Cc1cccc2c1nccc2,1 +Cc1cccc2c1nn[nH]2,0 +Cc1ccccc1,0 +Cc1ccccc1/N=N/c1c(O)ccc2c1cccc2,1 +Cc1ccccc1/N=N/c1ccc(c(c1N)C)N,1 +Cc1ccccc1/N=N/c1ccc(cc1)N(C)C,0 +Cc1ccccc1Br,0 +Cc1ccccc1C,0 +Cc1ccccc1C.Cc1cccc(c1)C.Cc1ccc(cc1)C,0 +Cc1ccccc1Cl,0 +Cc1ccccc1N,1 +Cc1ccccc1N.Cl,1 +Cc1ccccc1N=Nc1c(O)ccc2c1cccc2,1 +Cc1ccccc1N=Nc1ccc(c(c1N)C)N,1 +Cc1ccccc1N=Nc1ccc(cc1)N(C)C,0 +Cc1ccccc1NS(=O)(=O)c1cccc2c1nccc2,0 +Cc1ccccc1O,0 +Cc1ccccc1O.Cc1cccc(c1)O.Cc1ccc(cc1)O,0 +Cc1ccccc1OC[C@H]1CO1,1 +Cc1ccccc1OP(=O)(Oc1ccccc1C)Oc1ccccc1C,1 +Cc1ccccc1S(=O)(=O)N,0 +Cc1ccccc1c1c(N)[nH]n(c1=O)C(C)C,0 +Cc1ccccc1c1ccccc1,0 +Cc1ccccc1c1nc2c(o1)cccc2,0 +Cc1ccccn1,0 +Cc1cccnc1,0 +Cc1ccco1,0 +Cc1cccs1,0 +Cc1ccnc2c1cccc2,1 +Cc1ccncc1,0 +Cc1cn(CC(CN=N#N)O)c(=O)[nH]c1=O,1 +Cc1cn(CC(CN=N#N)O)c(=O)nc1OC,1 +Cc1cn2c(s1)nc(c2[N+](=O)[O-])c1ccc(cc1)[N+](=O)[O-],1 +Cc1cnc(c(n1)C)C,0 +Cc1cnc2c(c1)ccc(c2C(=O)O)Cl,0 +Cc1cnc2c(c1)cccc2,1 +Cc1cnc2c(n1)c(C)c(c1c2nc(n1C)N)C,1 +Cc1cnc2c(n1)c(C)c1c(c2)nc(n1C)N,1 +Cc1cnc2c(n1)c(C)cc1c2nc(n1C)N,1 +Cc1cnc2c(n1)c1nc(n(c1c(c2)C)C)N,1 +Cc1cnc2c(n1)c1nc(n(c1c(c2C)C)C)N,1 +Cc1cnc2c(n1)c1nc(n(c1cc2)C)N,1 +Cc1cnc2c(n1)c1nc(n(c1cc2)C)NS(=O)(=O)O,0 +Cc1cnc2c(n1)c1nc(n(c1cc2C)C)N,1 +Cc1cnc2c(n1)c1ncn(c1cc2)C,0 +Cc1cnc2c(n1)cc(c1c2nc(n1C)N)C,1 +Cc1cnc2c(n1)ccc1c2nc(n1C)N,1 +Cc1cnc2c(n1)cccc2,0 +Cc1cncc(n1)C,1 +Cc1cnccn1,0 +Cc1cscc1,0 +Cc1n[n+]([O-])c(c(=O)n1N)c1ccccc1,1 +Cc1n[nH]c(=O)[nH]c1=O,0 +Cc1nc(C)cc(c1)c1cc2c(cc1F)n1c(n2C2CC2)cc(=O)[nH]c1=O,1 +Cc1nc(C)cc(c1)c1cc2c(cc1F)n1c(n2C2CC2)cc(=O)n(c1=O)O,1 +Cc1nc(N)nc(n1)N,0 +Cc1nc(Nc2cccc(c2)O)nc(c1)C1CC1,0 +Cc1nc(Nc2ccccc2)nc(c1)C1CC1,0 +Cc1nc(nc(n1)O)NC(=O)NS(=O)(=O)c1ccsc1C(=O)O,0 +Cc1nc2c(nc1C)c(C)c(c1c2nc(n1C)N)C,1 +Cc1nc2c(nc1C)c(C)cc1c2nc(n1C)N,1 +Cc1nc2c(nc1C)cc(c1c2nc(n1C)N)C,1 +Cc1nc2c(nc1C)ccc(c2C)N,1 +Cc1nc2c(nc1C)ccc1c2nc(n1C)N,1 +Cc1nc2c(s1)cccc2,0 +Cc1ncc(nc1)C,0 +Cc1ncc2c(n1)CCC2,0 +Cc1ncc[nH]1,0 +Cc1nccc2c1[nH]c1c2cccc1,1 +Cc1nccc2c1[nH]c1c2cccc1.Cl,1 +Cc1nccnc1C,0 +Cc1nn(c(c1/C=N/OCc1ccc(cc1)C(=O)OC(C)(C)C)Oc1ccccc1)C,0 +Cc1nnc(c(=O)n1N)c1ccccc1,0 +Cc1nsc(c1)N,1 +Cc1nsc(c1)N.Cl,1 +Cc1scc(n1)c1ccc(o1)[N+](=O)[O-],1 +Cl/C(=C(\C(=C(Cl)Cl)Cl)/Cl)/SCc1ccccc1,1 +Cl/C(=C(\C(=C(Cl)Cl)Cl)/Cl)/SSc1ccccc1[N+](=O)[O-],1 +Cl/C(=C(\C(F)(F)F)/Cl)/SSc1ccccc1[N+](=O)[O-],1 +Cl/C(=C\[C@@H]1[C@@H](C1(C)C)C(=O)O)/C(F)(F)F,0 +Cl/C(=C\[C@H]1[C@H](C1(C)C)C(=O)O)/C(F)(F)F,0 +Cl/C=C(/C(Cl)Cl)\Cl,1 +Cl/C=C(/CSC(=O)N(C(C)C)C(C)C)\Cl,1 +Cl/C=C(/SCC(C(=O)NCC(=O)O)NC(=O)CCC(C(=O)O)N)\Cl,1 +Cl/C=C(/SCC(C(=O)O)NC(=O)C)\Cl,1 +Cl/C=C(/c1c(Cl)c(Cl)c(c(c1Cl)Cl)Cl)\Cl,0 +Cl/C=C(/c1cc(Cl)c(cc1Cl)Cl)\OP(=O)(OC)OC,0 +Cl/C=C(\C(Cl)Cl)/Cl,1 +Cl/C=C(\SCc1ccccc1)/Cl,1 +Cl/C=C/CO/N=C(/C1=C(O)CC(CC1=O)(O)CC(S(=O)(=O)CC)C)\CC,0 +Cl/C=C/CO/N=C(/C1=C(O)CC(CC1=O)CC(S(=O)(=O)CC)C)\CC,1 +Cl/C=C/CO/N=C(/C1=C(O)CC(CC1=O)CC(SCC)C)\CC,1 +Cl/C=C/CSCC(C(=O)O)N,0 +Cl/C=C/C[N@+]12CN3CN(C2)CN(C1)C3,1 +Cl/C=C/c1c(Cl)c(Cl)c(c(c1Cl)Cl)Cl,0 +Cl/C=C\C[N+]12CN3CN(C2)CN(C1)C3,1 +Cl/C=C\Cl,0 +ClC#N,0 +ClC(/C(=C(/C(=O)O)\Cl)/C(=O)O)Cl,1 +ClC(/C(=C(\C(=O)O)/Cl)/C(=O)O)Cl,1 +ClC(=C(Cl)Cl)C(=C(Cl)Cl)Cl,0 +ClC(=C(Cl)Cl)CS(=O)(=O)O,0 +ClC(=C(Cl)Cl)Cl,0 +ClC(=C(SSc1ccccc1[N+](=O)[O-])Cl)Cl,1 +ClC(=C(SSc1ccccc1[N+](=O)[O-])F)Cl,1 +ClC(=C(c1c(Cl)c(Cl)c(c(c1Cl)Cl)Cl)Cl)Cl,0 +ClC(=C(c1ccc(cc1)Cl)c1ccc(cc1)Cl)Cl,0 +ClC(=C)C#N,0 +ClC(=C)C=O,1 +ClC(=C1C(=O)NC(=O)C1(Cl)Cl)Cl,1 +ClC(=C1C=CC(=O)O1)Cl,1 +ClC(=C1OC(=O)C(=C1)Cl)Cl,1 +ClC(=C1OC(=O)C(=C1Cl)Cl)Cl,1 +ClC(=CCOc1cc(Cl)c(c(c1)Cl)OCCCOc1cccc(n1)C(F)(F)F)Cl,0 +ClC(=C[C@H]1[C@@H](C1(C)C)C(=O)OCc1cccc(c1)Oc1ccccc1)Cl,1 +ClC(=Cc1c(Cl)c(Cl)c(c(c1Cl)Cl)Cl)Cl,0 +ClC(=O)C(Cl)Cl,1 +ClC(=O)CCc1ccccc1,1 +ClC(=O)Cc1ccccc1,1 +ClC(=O)OCC1c2ccccc2-c2c1cccc2,1 +ClC(=O)OCc1ccccc1,0 +ClC(=O)c1c(Cl)cccc1Cl,1 +ClC(=O)c1cc(cc(c1)[N+](=O)[O-])[N+](=O)[O-],1 +ClC(=O)c1ccc(cc1)C(=O)Cl,1 +ClC(=O)c1ccc(cc1)C,1 +ClC(=O)c1ccc(cc1)[N+](=O)[O-],1 +ClC(=O)c1cccc(c1)[N+](=O)[O-],1 +ClC(=O)c1ccccc1,1 +ClC(=O)c1ccccc1C(=O)Cl,1 +ClC(=O)c1ccccc1C,1 +ClC(=O)c1ccccc1Cl,1 +ClC(=O)c1ccccc1F,1 +ClC(Br)(Cl)Cl,1 +ClC(Br)Br,0 +ClC(C#N)Cl,1 +ClC(C(=C(C(=O)O)Cl)C(Cl)Cl)Cl,1 +ClC(C(=CC(=O)O)C(Cl)Cl)Cl,1 +ClC(C(=O)C(Cl)(Cl)Cl)Cl,1 +ClC(C(=O)C(Cl)Cl)Cl,1 +ClC(C(=O)C)Cl,1 +ClC(C(=O)N1CCN(C1=O)c1ncc(s1)[N+](=O)[O-])Cl,1 +ClC(C(=O)Nc1snc2c1cc(C)cc2)Cl,1 +ClC(C(=O)O)Cl,1 +ClC(C(C(F)(F)F)(F)F)Cl,0 +ClC(C(Cl)(Cl)Cl)(Cl)Cl,0 +ClC(C(Cl)(Cl)Cl)COCC(C(Cl)(Cl)Cl)Cl,1 +ClC(C(Cl)(Cl)Cl)Cl,0 +ClC(C(Cl)Cl)Cl,0 +ClC(C(c1ccc(cc1)Cl)c1ccc(cc1)Cl)(Cl)Cl,0 +ClC(C(c1ccc(cc1)Cl)c1ccc(cc1)Cl)Cl,0 +ClC(C1=C(Cl)C(=O)OC1)Cl,1 +ClC(C1=C(Cl)C(=O)OC1O)Br,1 +ClC(C1=C(Cl)C(=O)O[C@H]1O)Cl,1 +ClC(C[C@@H]1OC1)(Cl)Cl,1 +ClC(Cl)(Cl)Cl,0 +ClC(Cl)Cl,0 +ClC(SN1C(=O)C2C(C1=O)CC=CC2)(Cl)Cl,1 +ClC(SN1C(=O)[C@H]2[C@H](C1=O)CC=CC2)(Cl)Cl,1 +ClC(SN1C(=O)c2c(C1=O)cccc2)(Cl)Cl,1 +ClC([C@@H](c1ccccc1Cl)c1ccc(cc1)Cl)Cl,0 +ClC([C@H]1OC1)(Cl)Cl,1 +ClC([N+](=O)[O-])(Cl)Cl,1 +ClC([N+](=O)[O-])Cl,1 +ClC(c1ccccc1)(Cl)Cl,1 +ClC(c1ccccc1)C(=O)Cl,1 +ClC(c1ccccc1)C(=O)NCc1ccccc1,1 +ClC(c1ccccc1)Cl,1 +ClC/C(=C(/C(=O)O)\Cl)/C(Cl)Cl,1 +ClC/C(=C(\C(=O)O)/Cl)/C(=O)O,0 +ClC/C(=C(\C(=O)O)/Cl)/C=O,1 +ClC/C=C/CCl,1 +ClC/C=C/Cl,1 +ClC/C=C\Cl,1 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+ClCCCCN(COC(=O)C)N=O,1 +ClCCCN(C)C,1 +ClCCCN(COC(=O)C)N=O,1 +ClCCCNC(=O)SCC(C(=O)NCC(=O)O)NC(=O)CCC(C(=O)O)N,1 +ClCCCc1cn(C2CC(C(O2)CO)O)c(=O)[nH]c1=O,0 +ClCCCl,1 +ClCCN(C(=O)NC(C(C(C(CO)O)O)O)C=O)N=O,1 +ClCCN(C(=O)NC1CCC(CC1)C)N=O,1 +ClCCN(C(=O)NC1CCCCC1)N=O,1 +ClCCN(C(=O)NCC(=O)N)N=O,1 +ClCCN(C(=O)NCCS(=O)(=O)N(C)C)N=O,1 +ClCCN(C(=O)NCc1cnc(nc1N)C)N=O,1 +ClCCN(C(=O)N[C@@H](P(=O)(OCC)OCC)C)N=O,1 +ClCCN(C(=O)N[C@@H]1CC[C@H](CC1)C)N=O,1 +ClCCN(C)C,1 +ClCCN(CCCNc1c2CCCCc2nc2c1cccc2)CC,1 +ClCCN(CCCNc1c2cc(OC)ccc2nc2c1ccc(c2)Cl)CC,1 +ClCCN(CCCNc1c2cc(OC)ccc2nc2c1ccc(c2)Cl)CC.Cl.Cl,1 +ClCCN(CCCNc1c2ccc(cc2nc2c1nc(OC)cc2)Cl)CC,1 +ClCCN(CCCNc1c2ccc(cc2nc2c1nc(OC)cc2)Cl)CC.Cl.Cl,1 +ClCCN(CCCNc1c2ccccc2nc2c1ccc1c2cccc1)CC,1 +ClCCN(CCCNc1c2ccccc2nc2c1ccc1c2cccc1)CC.Cl.Cl,1 +ClCCN(CCCNc1c2ccccc2nc2c1ccc1c2nccc1)CC,1 +ClCCN(CCCNc1c2ccccc2nc2c1ccc1c2nccc1)CC.Cl.Cl,1 +ClCCN(CCCNc1c2ccccc2nc2c1cccc2)CC,1 +ClCCN(CCCNc1c2ccccc2nc2c1cccc2)CC.Cl.Cl,1 +ClCCN(CCCNc1c2ccccc2nc2c1cccc2OC)CC,1 +ClCCN(CCCNc1c2ccccc2nc2c1cccc2OC)CC.Cl.Cl,1 +ClCCN(CCCl)C,1 +ClCCN(CCCl)CCCC(Nc1c2cc(OC)ccc2nc2c1ccc(c2)Cl)C,1 +ClCCN(CCCl)CCC[C@H](Nc1c2cc(OC)ccc2nc2c1ccc(c2)Cl)C,1 +ClCCN(CCCl)CCCl,0 +ClCCN(P(=O)(O)N)CCCl,1 +ClCCN(P(=O)(OCCC(=O)O)N)CCCl,1 +ClCCN(P1(=O)OCC(=O)CO1)CCCl,1 +ClCCN(P1(=O)OCCC(=O)N1)CCCl,1 +ClCCN(P1(=O)OCCCN1CCCl)CCCl,1 +ClCCN([C@@H](COc1ccccc1)C)Cc1ccccc1,1 +ClCCN([P@@](=O)(OCCC(=O)O)N)CCCl,1 +ClCCN([P@](=O)(O)N)CCCl,1 +ClCCN([P@]1(=O)NCCCO1)CCCl,1 +ClCCN([P@]1(=O)OCCCN1CCCl)CCCl,1 +ClCCN([P@]1(=O)OCC[C@H](N1)O)CCCl,1 +ClCCN(c1c(OC)ccc2c1cc(o2)[N+](=O)[O-])CCCl,1 +ClCCN(c1cc(ccc1C)C(P(=O)(O)O)(P(=O)(O)O)O)CCCl,1 +ClCCN(c1ccc(c2c1cc(o2)[N+](=O)[O-])OC)CCCl,1 +ClCCN(c1ccc(c2c1oc(c2)[N+](=O)[O-])OC)CCCl,1 +ClCCN(c1ccc(cc1)C)CCCl,0 +ClCCN(c1ccc(cc1)CC(=O)O[C@H]1CC[C@]2(C(=CC[C@@H]3[C@@H]2CC[C@]2([C@H]3CC[C@@H]2[C@@H](CCCC(C)C)C)C)C1)C)CCCl,0 +ClCCN(c1ccc(cc1)CC(=O)O[C@H]1CC[C@]2([C@H](C1)CC[C@@H]1[C@@H]2CC[C@]2([C@H]1CCC(=O)N2)C)C)CCCl,1 +ClCCN(c1ccc(cc1)CCCC(=O)O)CCCl,1 +ClCCN(c1ccc(cc1)CCCC(=O)O[C@H]1CC[C@@H]2[C@]1(C)CC[C@H]1[C@H]2CC=C2[C@]1(C)CCC(=O)N2)CCCl,1 +ClCCN(c1ccc(cc1)CCCNc1c2ccccc2nc2c1cccc2)CC,1 +ClCCN(c1ccc(cc1)C[C@@H](C(=O)O)N)CCCl,1 +ClCCN(c1ccc(cc1)C[C@H](C(=O)O)N)CCCl,1 +ClCCN(c1ccc(cc1)OCC(=O)O)CCCl,1 +ClCCN(c1ccc(cc1)OCC(=O)O[C@H]1CC[C@]2([C@H](C1)CC[C@@H]1[C@@H]2CC[C@]2([C@H]1CCC(=O)N2)C)C)CCCl,1 +ClCCN(c1ccc(cc1)OCCCCCNc1c2ccccc2nc2c1cccc2)CC,1 +ClCCN(c1ccc(cc1)c1[nH]c2c(n1)cc(cc2)CCCCCCc1nc2c([nH]1)ccc(c2)N1CCN(CC1)C)CCCl,0 +ClCCN(c1ccc(cc1)c1[nH]c2c(n1)cc(cc2)Cc1nc2c([nH]1)ccc(c2)N1CCN(CC1)C)CCCl,0 +ClCCN(c1ccc(cc1)c1[nH]c2c(n1)cc(cc2)c1nc2c([nH]1)ccc(c2)N1CCN(CC1)C)CC,0 +ClCCN(c1ccc(cc1)c1[nH]c2c(n1)cc(cc2)c1nc2c([nH]1)ccc(c2)N1CCN(CC1)C)CCCl,0 +ClCCN(c1ccc2c(c1)cc(o2)[N+](=O)[O-])CCCl,1 +ClCCN(c1ccc2c(c1)ccc1c2cc(o1)[N+](=O)[O-])CCCl,1 +ClCCN(c1ccc2c(c1)cccc2)CCCl,1 +ClCCN(c1ccc2c(c1)oc(c2)[N+](=O)[O-])CCCl,1 +ClCCN(c1cccc(c1)/C=C/C(=O)OC1CCC2(C(C1)CCC1C2CCC2(C1CCC(=O)N2)C)C)CCCl,1 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+Nc1cc2nc3cc(N)c(cc3cc2cc1C)C,1 +Nc1cc2nc3ccccc3nc2cc1N,1 +Nc1cc2nc3ccccc3nc2cc1O,1 +Nc1ccc(c(c1)C(=O)O)O,0 +Nc1ccc(c(c1)C(F)(F)F)Cl,0 +Nc1ccc(c(c1)C)C,1 +Nc1ccc(c(c1)C)N,1 +Nc1ccc(c(c1)C)c1ccc(cc1C)N,1 +Nc1ccc(c(c1)Cl)C,1 +Nc1ccc(c(c1)Cl)C.Cl,0 +Nc1ccc(c(c1)Cl)Cl,0 +Nc1ccc(c(c1)Cl)c1ccc(cc1Cl)N,1 +Nc1ccc(c(c1)N)/N=N/c1ccc(cc1)c1ccc(cc1)/N=N/c1c(N)c2c(cc1S(=O)(=O)O)cc(c(c2O)/N=N/c1ccccc1)S(=O)(=O)O,1 +Nc1ccc(c(c1)N)/N=N/c1ccc2c(c1)c(O)c(c(c2)S(=O)(=O)O)/N=N/c1ccc(cc1)Nc1ccc(cc1S(=O)(=O)O)/N=N/c1c(O)c2cc(/N=N/c3ccc(cc3N)N)ccc2cc1S(=O)(=O)O,1 +Nc1ccc(c(c1)N)C,1 +Nc1ccc(c(c1)N)Cl,1 +Nc1ccc(c(c1)N)N=Nc1ccc2c(c1)c(O)c(c(c2)S(=O)(=O)O)N=Nc1ccc(cc1)Nc1ccc(cc1S(=O)(=O)O)N=Nc1c(O)c2cc(N=Nc3ccc(cc3N)N)ccc2cc1S(=O)(=O)O,1 +Nc1ccc(c(c1)N)N=Nc1cccc(c1)N=Nc1ccc(cc1N)N,1 +Nc1ccc(c(c1)N)N=Nc1ccccc1,1 +Nc1ccc(c(c1)N)O,1 +Nc1ccc(c(c1)N)[N+](=O)[O-],1 +Nc1ccc(c(c1)N=[N+](c1cc(N)ccc1C)[O-])C,1 +Nc1ccc(c(c1)O)C,1 +Nc1ccc(c(c1)O)[N+](=O)[O-],1 +Nc1ccc(c(c1)S(=O)(=O)O)/C=C/c1ccc(cc1S(=O)(=O)O)N,0 +Nc1ccc(c(c1)S(=O)(=O)O)/C=C/c1ccc(cc1S(=O)(=O)O)N.[Na+].[Na+],0 +Nc1ccc(c(c1)S(=O)(=O)O)/C=C\c1ccc(cc1S(=O)(=O)O)N,0 +Nc1ccc(c(c1)S(=O)(=O)O)N,0 +Nc1ccc(c(c1)S(=O)(=O)O)c1ccc(cc1S(=O)(=O)O)N,0 +Nc1ccc(c(c1)[N+](=O)[O-])C,1 +Nc1ccc(c(c1)[N+](=O)[O-])Cc1ccc(cc1[N+](=O)[O-])N,1 +Nc1ccc(c(c1)[N+](=O)[O-])N,1 +Nc1ccc(c(c1)[N+](=O)[O-])O,1 +Nc1ccc(c(c1)[N+](=O)[O-])c1ccc(cc1N)[N+](=O)[O-],1 +Nc1ccc(c(c1)[N+](=O)[O-])c1ccc(cc1[N+](=O)[O-])N,1 +Nc1ccc(c(c1C)N)/N=N/c1ccccc1,1 +Nc1ccc(c(c1C)N)N=Nc1ccccc1,1 +Nc1ccc(c(c1Cl)Cl)Cl,0 +Nc1ccc(c2c1C(=O)c1c(C2=O)cccc1[N+](=O)[O-])N,1 +Nc1ccc(c2c1C(=O)c1c(O)ccc(c1C2=O)N)O,1 +Nc1ccc(c2c1C(=O)c1ccccc1C2=O)N,1 +Nc1ccc(c2c1cccc2)N,1 +Nc1ccc(c2c1cccc2)S(=O)(=O)O,0 +Nc1ccc(cc1)/C=C/c1ccc(cc1)C(C)(C)C,0 +Nc1ccc(cc1)/C=C/c1ccc(cc1)Cl,1 +Nc1ccc(cc1)/C=C/c1ccc(cc1)N,1 +Nc1ccc(cc1)/C=C/c1ccc(cc1)[N+](=O)[O-],1 +Nc1ccc(cc1)/C=C/c1cccc(c1)Cl,1 +Nc1ccc(cc1)/C=C/c1cccc(c1)N,1 +Nc1ccc(cc1)/C=C/c1ccccc1,1 +Nc1ccc(cc1)/N=N/c1ccc(cc1)N,1 +Nc1ccc(cc1)/N=N/c1ccccc1,1 +Nc1ccc(cc1)Br,0 +Nc1ccc(cc1)C(=O)N,0 +Nc1ccc(cc1)CCc1ccc(cc1)N,1 +Nc1ccc(cc1)CCc1ccccc1,1 +Nc1ccc(cc1)Cc1ccc(c(c1)Cc1ccc(cc1)N)N,1 +Nc1ccc(cc1)Cc1ccc(cc1)N,1 +Nc1ccc(cc1)Cc1ccc(cc1)N.Cl.Cl,1 +Nc1ccc(cc1)Cl,1 +Nc1ccc(cc1)Cl.Cl,1 +Nc1ccc(cc1)F,1 +Nc1ccc(cc1)N(c1ccc2c(c1)cccc2)c1ccc2c(c1)cccc2,0 +Nc1ccc(cc1)N,1 +Nc1ccc(cc1)N.Cl.Cl,1 +Nc1ccc(cc1)N=Nc1ccc(cc1)N,1 +Nc1ccc(cc1)N=Nc1cccc(c1N)N,1 +Nc1ccc(cc1)N=Nc1ccccc1,1 +Nc1ccc(cc1)NC(=O)c1ccc(cc1)C(=O)O,0 +Nc1ccc(cc1)Nc1c2ccccc2nc2c1cccc2,1 +Nc1ccc(cc1)Nc1ccc(cc1)[N+](=O)[O-],1 +Nc1ccc(cc1)Nc1ccccc1,0 +Nc1ccc(cc1)O,0 +Nc1ccc(cc1)Oc1c(Cl)cc(cc1Cl)Cl,1 +Nc1ccc(cc1)Oc1ccc(c(c1)N)N,1 +Nc1ccc(cc1)Oc1ccc(cc1)N,1 +Nc1ccc(cc1)Oc1ccc(cc1)Oc1ccc(cc1)N,1 +Nc1ccc(cc1)Oc1ccc(cc1)[N+](=O)[O-],1 +Nc1ccc(cc1)Oc1ccc(cc1Cl)Cl,1 +Nc1ccc(cc1)Oc1cccc(c1)Oc1ccc(cc1)N,1 +Nc1ccc(cc1)Oc1ccccc1,1 +Nc1ccc(cc1)S(=O)(=O)N,0 +Nc1ccc(cc1)S(=O)(=O)Nc1ccccn1,0 +Nc1ccc(cc1)S(=O)(=O)Nc1cnc2c(n1)cccc2Cl,0 +Nc1ccc(cc1)S(=O)(=O)Nc1nc(C)cc(n1)C,0 +Nc1ccc(cc1)S(=O)(=O)Nc1nccs1,0 +Nc1ccc(cc1)S(=O)(=O)Nc1nnc(s1)C,0 +Nc1ccc(cc1)S(=O)(=O)Nc1noc(c1)C,0 +Nc1ccc(cc1)S(=O)(=O)Nc1onc(c1C)C,0 +Nc1ccc(cc1)S(=O)(=O)O,0 +Nc1ccc(cc1)S(=O)(=O)c1ccc(cc1)N,0 +Nc1ccc(cc1)Sc1ccc(cc1)N,1 +Nc1ccc(cc1)Sc1ccc(cc1)[N+](=O)[O-],1 +Nc1ccc(cc1)Sc1ccccc1,1 +Nc1ccc(cc1)[N+](=O)[O-],1 +Nc1ccc(cc1)c1[n+](C)c2cc(N)ccc2c2c1cc(N)cc2,1 +Nc1ccc(cc1)c1cc(Cl)c(c(c1)Cl)N,1 +Nc1ccc(cc1)c1ccc(c(c1)[N+](=O)[O-])N,1 +Nc1ccc(cc1)c1ccc(cc1)Cl,1 +Nc1ccc(cc1)c1ccc(cc1)N,1 +Nc1ccc(cc1)c1ccc(cc1)N.Cl.Cl,1 +Nc1ccc(cc1)c1ccc(cc1)[N+](=O)[O-],1 +Nc1ccc(cc1)c1ccc(cc1)c1ccc(cc1)N,1 +Nc1ccc(cc1)c1ccc(cc1)c1ccc(cc1)c1ccc(cc1)N,0 +Nc1ccc(cc1)c1ccc(cc1[N+](=O)[O-])N,1 +Nc1ccc(cc1)c1ccccc1,1 +Nc1ccc(cc1)c1ccccc1C,1 +Nc1ccc(cc1)c1nc2c(s1)c(c(cc2)C)S(=O)(=O)O,1 +Nc1ccc(cc1)c1nc2c(s1)cc(cc2)C,1 +Nc1ccc(cc1Br)c1ccc(c(c1)Br)N,1 +Nc1ccc(cc1C)Cc1ccc(c(c1)C)N,1 +Nc1ccc(cc1C)NOS(=O)(=O)O,1 +Nc1ccc(cc1C)S(=O)(=O)O,0 +Nc1ccc(cc1C)c1ccc(c(c1)C)N,1 +Nc1ccc(cc1Cl)C(F)(F)F,0 +Nc1ccc(cc1Cl)Cc1cc(O)c(c(c1)Cl)N,0 +Nc1ccc(cc1Cl)Cc1ccc(c(c1)Cl)N,1 +Nc1ccc(cc1Cl)NOS(=O)(=O)O,1 +Nc1ccc(cc1Cl)Oc1ccc(c(c1)Cl)N,1 +Nc1ccc(cc1Cl)c1cc(Cl)c(c(c1)Cl)N,1 +Nc1ccc(cc1Cl)c1ccc(c(c1)Cl)N,1 +Nc1ccc(cc1F)c1ccc(c(c1)F)N,1 +Nc1ccc(cc1N)c1ccc(c(c1)N)N,1 +Nc1ccc(cc1O)c1ccc(c(c1)O)N,1 +Nc1ccc2-c3c(-c4c2c1ccc4)cccc3,1 +Nc1ccc2-c3c(Cc2c1)cc(cc3)N,1 +Nc1ccc2-c3c(Cc2c1)cc(cc3)[N+](=O)[O-],1 +Nc1ccc2-c3c(Cc2c1)cccc3,1 +Nc1ccc2-c3c(Cc2c1C(C)(C)C)cccc3,0 +Nc1ccc2-c3c4c(-c2c1)cccc4ccc3,1 +Nc1ccc2-c3n(Cc2c1)c(=O)c1c(n3)cccc1,1 +Nc1ccc2c(-c3ccccc3C2)c1,1 +Nc1ccc2c(c1)C(=O)c1c(C2=O)cc(cc1)N,1 +Nc1ccc2c(c1)C(=O)c1c(C2=O)cccc1,1 +Nc1ccc2c(c1)CN1C(=N2)c2c(C1=O)cccc2,1 +Nc1ccc2c(c1)[n+](C)c1c(c2)ccc(c1)N,1 +Nc1ccc2c(c1)[n+](C)c1c(c2)ccc(c1)N.Nc1ccc2c(c1)nc1c(c2)ccc(c1)N.Cl,1 +Nc1ccc2c(c1)[n+](C)c1c(c2)cccc1,1 +Nc1ccc2c(c1)[n+](C)c1c(c2)cccc1.Cl,1 +Nc1ccc2c(c1)[nH]c1c2cccc1,1 +Nc1ccc2c(c1)[o+]c1c(c2c2ccccc2C(=O)O)ccc(c1)N,0 +Nc1ccc2c(c1)[s+]c1c(n2)ccc(c1)N,1 +Nc1ccc2c(c1)[s+]c1c(n2)ccc(c1)N.Cl,1 +Nc1ccc2c(c1)c(Cl)ns2,1 +Nc1ccc2c(c1)c(N)c1c(n2)cccc1,1 +Nc1ccc2c(c1)c(O)c(c(c2)S(=O)(=O)O)/N=N/c1ccc(cc1)c1ccc(cc1)/N=N/c1c(O)c2c(N)cc(cc2cc1S(=O)(=O)O)S(=O)(=O)O,1 +Nc1ccc2c(c1)c(O)c(c(c2)S(=O)(=O)O)/N=N/c1ccc(cc1)c1ccc(cc1)/N=N/c1ccc(c(c1)C(=O)O)O,1 +Nc1ccc2c(c1)c(O)c(c(c2)S(=O)(=O)O)N=Nc1ccc(cc1)c1ccc(cc1)N=Nc1c(O)c2c(N)cc(cc2cc1S(=O)(=O)O)S(=O)(=O)O,1 +Nc1ccc2c(c1)c(O)c(c(c2)S(=O)(=O)O)N=Nc1ccc(cc1)c1ccc(cc1)N=Nc1ccc(c(c1)C(=O)O)O,1 +Nc1ccc2c(c1)c1c(C)c3cnccc3c(c1[nH]2)C,1 +Nc1ccc2c(c1)c1ccccc1[nH]2,1 +Nc1ccc2c(c1)c1ccccc1cc2,1 +Nc1ccc2c(c1)c1ccccc1n2C,1 +Nc1ccc2c(c1)cc1c([n+]2C)cccc1,1 +Nc1ccc2c(c1)cc1c([n+]2C)cccc1.Cl,1 +Nc1ccc2c(c1)cc1c(c2)cccc1,1 +Nc1ccc2c(c1)cc1c(n2)cccc1,1 +Nc1ccc2c(c1)ccc1c2ccc2c1cccc2,1 +Nc1ccc2c(c1)ccc1c2cccc1,1 +Nc1ccc2c(c1)cccc2,1 +Nc1ccc2c(c1)cccn2,0 +Nc1ccc2c(c1)cns2,1 +Nc1ccc2c(c1)nc(c(n2)C)C,1 +Nc1ccc2c(c1)nc1c(c2)ccc(c1)N,1 +Nc1ccc2c(c1)nc1c(c2)ccc(c1)N.Cl,1 +Nc1ccc2c(c1)nc1c(c2)cccc1,1 +Nc1ccc2c(c1)nc1c(c2N)cccc1,1 +Nc1ccc2c(c1)nc1c(n2)c(N)ccc1,1 +Nc1ccc2c(c1)nc1c(n2)cc(cc1)N,1 +Nc1ccc2c(c1)nc1c(n2)ccc(c1)N,1 +Nc1ccc2c(c1)nc1c(n2)cccc1,1 +Nc1ccc2c(c1)nccc2,1 +Nc1ccc2c(c1)oc(=O)cc2C,0 +Nc1ccc2c(c1)oc1-c(c2c2ccccc2C(=O)O)ccc(=N)c1,0 +Nc1ccc2c(c1)oc1-c(n2)c2ccccc2c(=N)c1,1 +Nc1ccc2c(c1)oc1c2cccc1,1 +Nc1ccc2c(c1)s[nH]c2=O,0 +Nc1ccc2c(c1)scn2,1 +Nc1ccc2c(c1/N=N/c1ccc(cc1)[N+](=O)[O-])cccc2,1 +Nc1ccc2c(c1/N=N/c1ccc(cc1)c1ccc(cc1)/N=N/c1c(N)ccc3c1c(O)cc(c3)S(=O)(=O)O)c(O)cc(c2)S(=O)(=O)O,1 +Nc1ccc2c(c1/N=N/c1ccc(cc1)c1ccc(cc1)/N=N/c1cc(c3c(c1N)cccc3)S(=O)(=O)O)c(O)cc(c2)S(=O)(=O)O,1 +Nc1ccc2c(c1/N=N/c1ccc(cc1S(=O)(=O)O)[N+](=O)[O-])c(O)cc(c2)S(=O)(=O)O,0 +Nc1ccc2c(c1/N=N/c1ccccc1)cccc2,0 +Nc1ccc2c(c1C(C)(C)C)cccc2,0 +Nc1ccc2c(c1N=Nc1ccc(cc1)[N+](=O)[O-])cccc2,1 +Nc1ccc2c(c1N=Nc1ccc(cc1)c1ccc(cc1)N=Nc1c(N)ccc3c1c(O)cc(c3)S(=O)(=O)O)c(O)cc(c2)S(=O)(=O)O,1 +Nc1ccc2c(c1N=Nc1ccc(cc1)c1ccc(cc1)N=Nc1cc(c3c(c1N)cccc3)S(=O)(=O)O)c(O)cc(c2)S(=O)(=O)O,1 +Nc1ccc2c(c1N=Nc1ccc(cc1S(=O)(=O)O)[N+](=O)[O-])c(O)cc(c2)S(=O)(=O)O,0 +Nc1ccc2c(c1N=Nc1ccccc1)cccc2,0 +Nc1ccc2c(c1S(=O)(=O)O)cccc2,1 +Nc1ccc2c(n1)[nH]c1c2cccc1,1 +Nc1ccc2c(n1)c1ccccc1cc2,1 +Nc1ccc2c(n1)cccc2,1 +Nc1ccc2c(n1)n1cccc(c1n2)C,1 +Nc1ccc2c(n1)n1ccccc1n2,1 +Nc1ccc2c(n1)no[n+]2[O-],1 +Nc1ccc2c3c1-c1ccccc1-c3ccc2,1 +Nc1ccc2c3c1ccc1c3c(cc2)c2c(c1)cccc2,1 +Nc1ccc2c3c1ccc1c3c(cc2)cc2c1cccc2,1 +Nc1ccc2c3c1ccc1c3c(cc2)ccc1,1 +Nc1ccc2c3c1ccc1c3c(cc2)ccc1[N+](=O)[O-],1 +Nc1cccc(c1)C(F)(F)F,0 +Nc1cccc(c1)Cl,0 +Nc1cccc(c1)N,1 +Nc1cccc(c1)O,1 +Nc1cccc(c1)S(=O)(=O)O,0 +Nc1cccc(c1)[N+](=O)[O-],1 +Nc1cccc(c1)c1ccccc1,1 +Nc1cccc(c1C)N,1 +Nc1cccc(c1C)N.Cl.Cl,1 +Nc1cccc(n1)N,1 +Nc1cccc2-c3c(Cc12)cccc3,1 +Nc1cccc2-c3c4c(-c12)cccc4ccc3,1 +Nc1cccc2c1-c1ccccc1C2,1 +Nc1cccc2c1C(=O)c1cccc(c1C2=O)N,1 +Nc1cccc2c1C(=O)c1ccccc1C2=O,1 +Nc1cccc2c1c(=O)[nH][nH]c2=O,0 +Nc1cccc2c1c(N)c1c(n2)cccc1,1 +Nc1cccc2c1c(N)ccc2,1 +Nc1cccc2c1c(O)nnc2O,0 +Nc1cccc2c1c1ccccc1cc2,0 +Nc1cccc2c1cc1ccccc1c2,1 +Nc1cccc2c1cc1ccccc1n2,1 +Nc1cccc2c1ccc1c2cccc1,1 +Nc1cccc2c1cccc2,1 +Nc1cccc2c1cccc2N,1 +Nc1cccc2c1cccn2,1 +Nc1cccc2c1nc1CCCCc1c2,1 +Nc1cccc2c1nc1c(N)cccc1n2,0 +Nc1cccc2c1nc1cccc(c1n2)N,1 +Nc1cccc2c1nc1ccccc1n2,1 +Nc1cccc2c1nccc2,1 +Nc1cccc2c1snc2,1 +Nc1cccc2c1snc2Cl,1 +Nc1ccccc1,0 +Nc1ccccc1.Cl,0 +Nc1ccccc1C(F)(F)F,0 +Nc1ccccc1Cl,0 +Nc1ccccc1N,1 +Nc1ccccc1O,1 +Nc1ccccc1S(=O)(=O)O,1 +Nc1ccccc1S,1 +Nc1ccccc1SCCSc1ccccc1N,1 +Nc1ccccc1SCSc1ccccc1N,1 +Nc1ccccc1c1ccccc1,1 +Nc1ccccc1c1ccccc1.Cl,1 +Nc1ccccn1,0 +Nc1ccn(c(=O)n1)C1C=C(C(C1O)O)CO,0 +Nc1ccn(c(=O)n1)CC(CN=N#N)O,1 +Nc1ccn(c(=O)n1)[C@@H]1C=C([C@H]([C@H]1O)O)CO,0 +Nc1ccn(c(=O)n1)[C@@H]1CC[C@@H](O1)CO,1 +Nc1ccnc2c1cccc2,0 +Nc1cn[nH]c(=O)c1Cl,0 +Nc1cnc2c(c1)c1ccccc1cc2,1 +Nc1cnc2c(c1)cccc2,1 +Nc1cnc2c(c1)nc1n2cccc1,1 +Nc1cnc2c(c1C)nc1n2cccc1C,1 +Nc1cnn(c(=O)c1Cl)c1ccccc1,0 +Nc1cnn(c(=O)c1Cl)c1ccccc1,1 +Nc1n[nH]cn1,0 +Nc1nc(C)c2c(c1)[nH]c1c2cccc1,1 +Nc1nc(C)c2c(c1C)[nH]c1c2cccc1,1 +Nc1nc(N)c2c(n1)[nH]cn2,0 +Nc1nc(N)c2c(n1)nc(c(n2)c1ccccc1)N,0 +Nc1nc(N)c2c(n1)nc[nH]2,0 +Nc1nc(N)nc(n1)Cl,0 +Nc1nc(N)nc(n1)N,0 +Nc1nc(NC2CC2)nc(n1)N,0 +Nc1nc(O)c2c(n1)nn[nH]2,0 +Nc1nc(OCC(F)(F)F)nc(n1)N(C)C,0 +Nc1nc(nc(n1)Cl)NC(C)(C)C,0 +Nc1nc(nc(n1)N)c1ccc(o1)[N+](=O)[O-],1 +Nc1nc(nc(n1)O)NC(C)(C)C,0 +Nc1nc(nc2c1ncn2c1ccc(cc1)[N+](=O)[O-])c1ccc(cc1)[N+](=O)[O-],1 +Nc1nc2-c3cccnc3CCc2s1,1 +Nc1nc2c([nH]1)cccc2,0 +Nc1nc2c(n1C)c(C)cc1c2nccn1,1 +Nc1nc2c(n1C)cc1c(n2)nccc1,0 +Nc1nc2c(n1C)ccc1c2cccn1,1 +Nc1nc2c(n1C)ccc1c2ccnc1,1 +Nc1nc2c(n1C)ccc1c2cncc1,1 +Nc1nc2c(n1C)ccc1c2nccc1,1 +Nc1nc2c(s1)cc(cc2)[N+](=O)[O-],1 +Nc1nc2c(s1)ccc1c2cccn1,1 +Nc1nc2c(s1)cccc2,0 +Nc1ncc2c(n1)nc[nH]2,0 +Nc1nccs1,1 +Nc1ncn[nH]1,1 +Nc1ncnc2c1cnn2CC(CN=N#N)O,1 +Nc1ncnc2c1nc(n2c1ccc(cc1)[N+](=O)[O-])c1ccc(cc1)[N+](=O)[O-],1 +Nc1ncnc2c1nc[nH]2,1 +Nc1ncnc2c1ncn2C(c1ccccc1)(c1ccccc1)c1ccccc1,1 +Nc1ncnc2c1ncn2C(c1ccccc1)c1ccccc1,1 +Nc1ncnc2c1ncn2C,1 +Nc1ncnc2c1ncn2Cc1ccccc1,1 +Nc1nnc(s1)S,0 +Nc1sc2c(-c3cccnc3CC2(C)C)n1,1 +Nc1sc2c(n1)C1CCCNC1CC2,0 +Nc1sc2c(n1)c(C)ccc2,0 +Nc1sc2c(n1)c(Cl)ccc2,0 +Nc1sc2c(n1)cc(c(c2)C)C,1 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+[O-][N+](=O)c1ccc2c(c1)/c(=N/C(=O)c1ccc(cc1)[N+](=O)[O-])/sn2C(=O)c1ccc(cc1)[N+](=O)[O-],1 +[O-][N+](=O)c1ccc2c(c1)/c(=N/C(=O)c1ccccc1)/sn2C(=O)c1ccccc1,1 +[O-][N+](=O)c1ccc2c(c1)/c(=N/C(=O)c1ccccc1Cl)/sn2C(=O)c1ccccc1Cl,1 +[O-][N+](=O)c1ccc2c(c1)/c(=N/C(=O)c1ccccc1[N+](=O)[O-])/sn2C(=O)c1ccccc1[N+](=O)[O-],1 +[O-][N+](=O)c1ccc2c(c1)CC=C2,1 +[O-][N+](=O)c1ccc2c(c1)CCN2,1 +[O-][N+](=O)c1ccc2c(c1)NCC2,1 +[O-][N+](=O)c1ccc2c(c1)Oc1c(O2)cc(cc1)[N+](=O)[O-],1 +[O-][N+](=O)c1ccc2c(c1)Oc1c(O2)ccc(c1)[N+](=O)[O-],1 +[O-][N+](=O)c1ccc2c(c1)Oc1c(O2)cccc1,1 +[O-][N+](=O)c1ccc2c(c1)[nH]c1c2cccc1,1 +[O-][N+](=O)c1ccc2c(c1)[nH]nc2,1 +[O-][N+](=O)c1ccc2c(c1)c(/C=N/OCc1cccc(c1)[N+](=O)[O-])c(n2Cc1ccccc1)C,1 +[O-][N+](=O)c1ccc2c(c1)c(/C=N/OCc1ccccc1)c(n2Cc1cccc(c1)[N+](=O)[O-])C,1 +[O-][N+](=O)c1ccc2c(c1)c(=O)[nH][nH]c2=O,1 +[O-][N+](=O)c1ccc2c(c1)c(C)ccc2,1 +[O-][N+](=O)c1ccc2c(c1)c(Cn1cncc1)c(n2Cc1ccccc1)C,1 +[O-][N+](=O)c1ccc2c(c1)c(N)c1c(n2)cccc1,1 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+[O-][n+]1cnc2c(c1N)ncn2C(c1ccccc1)c1ccccc1,1 +[O-][n+]1cnc2c(c1N)ncn2Cc1ccccc1,1 +[O-][n+]1ncc2c(c1)cccc2,0 +[O-][n+]1ncc2c(c1)cccn2,0 +[O-][n+]1ncc2c(c1)ccnc2,0 +[O-][n+]1ncc2c(c1)nccc2,0 +[O-]c1ccc(cc1)[N+](=O)[O-].[Na+],0 +[O-]c1cccc2c1nccc2.[O-]c1cccc2c1nccc2.[Cu+2],1 +[S-]C(=S)NC.[Na+],1 +c1cc(/C=C/c2ccccc2)cc(c1)/C=C/c1ccccc1,0 +c1cc(OCC2CO2)c2c(c1)cns2,1 +c1cc(OC[C@H]2CO2)c2c(c1)cns2,1 +c1cc(cc(c1)c1ccccc1)c1ccccc1,0 +c1cc2C3OC3c3c2c(c1)c1cc2ccccc2cc1c3,1 +c1cc2C=Cc3c2c(c1)cc1c3c2ccccc2cc1,1 +c1cc2C=Cc3c2c(c1)cc1c3ccc2c1C=C[C@@H]1[C@H]2O1,1 +c1cc2CCc3c4c2c(c1)cc1c4c2c(c3)cccc2cc1,1 +c1cc2Cc3c4c2c(c1)ccc4ccc3,1 +c1cc2[C@@H]3N[C@@H]3c3c2c(c1)ccc3,1 +c1cc2[C@@H]3O[C@@H]3c3c2c(c1)c1cc2ccccc2cc1c3,1 +c1cc2cc3ccc4c(c3c3c2c(c1)C1OC31)cccc4,1 +c1cc2cc3ccc4c(c3c3c2c(c1)[C@H]1O[C@@H]31)cccc4,1 +c1cc2ccc3c4c2c(c1)c1cccc2c1c4c(cc3)cc2,1 +c1cc2ccc3c4c2c(c1)cc1c4c(C=C1)cc3,1 +c1cc2ccc3c4c2c(c1)cc1c4c2c(c3)cccc2cc1,1 +c1cc2ccc3c4c2c(c1)ccc4c1c2c3cccc2C=C1,1 +c1cc2ccc3c4c2c(c1)ccc4cc1c3C=C[C@@H]2[C@H]1O2,1 +c1cc2ccc3c4c2c(c1)ccc4cc1c3CC[C@@H]2[C@H]1O2,1 +c1cc2ccc3c4c2c(c1)ccc4cc1c3[C@@H]2O[C@@H]2C=C1,1 +c1cc2ccc3c4c2c(c1)ccc4cc1c3[C@@H]2O[C@@H]2CC1,1 +c1cc2ccc3c4c2c(c1)ccc4cc1c3cco1,1 +c1cc2ccc3c4c2c(c1)ccc4cc1c3occ1,1 +c1cc2ccc3c4c2c(c1)ccc4ccc3,1 +c1cc2ccc3c4c2c(c1)ccc4ccc3[C@H]1OC1,1 +c1cc2ccc3c4c2c(c1)ccc4cnc3,1 +c1cc2ccc3c4c2c(c1)ccc4nc1c3cccc1,1 +c1cc2ccc3c4c2c(c1)cnc4ccc3,1 +c1cc2ccc3c4c2c(n1)ccc4ccc3,1 +c1cc2ccc3c4c2c2c1ccc1c2c2c4c(cc3)ccc2cc1,1 +c1cc2cccc3c2c(c1)CC3,0 +c1cc2cccc3c2c(c1)c1cccc2c1c3ccc2,1 +c1cc[n+]2c(-c3cccc[n+]3CC2)c1,0 +c1ccc(cc1)/C=C/c1ccccc1,0 +c1ccc(cc1)/C=N/c1snc2c1cccc2,0 +c1ccc(cc1)/N=N/c1ccccc1,1 +c1ccc(cc1)C(c1ccccc1)c1ccccc1,0 +c1ccc(cc1)CN1C2C1c1ccccc1-c1c2cccc1,1 +c1ccc(cc1)CN1CCN=N1,1 +c1ccc(cc1)CN1[C@@H]2[C@H]1c1ccccc1-c1c2cccc1,1 +c1ccc(cc1)CNc1[nH]cnc2-c1ncn2,0 +c1ccc(cc1)CNc1ncnc2c1[nH]cn2,0 +c1ccc(cc1)Cc1ccc(cc1)C[C@H]1CO1,1 +c1ccc(cc1)Cc1ccccc1OCC1CO1,1 +c1ccc(cc1)Cc1ccccc1OC[C@H]1CO1,1 +c1ccc(cc1)Cn1cncc1,1 +c1ccc(cc1)N(c1ccccc1)c1ccccc1,0 +c1ccc(cc1)N/N=N/c1ccccc1,1 +c1ccc(cc1)N=Nc1ccccc1,1 +c1ccc(cc1)NN=Nc1ccccc1,1 +c1ccc(cc1)NNc1ccccc1,1 +c1ccc(cc1)Nc1ccc(cc1)Nc1ccccc1,1 +c1ccc(cc1)Nc1ccc2c(c1)cccc2,0 +c1ccc(cc1)Nc1cccc2c1cccc2,0 +c1ccc(cc1)Nc1ccccc1,0 +c1ccc(cc1)OP(Oc1ccccc1)Oc1ccccc1,0 +c1ccc(cc1)O[Si](Oc1ccccc1)(Oc1ccccc1)Oc1ccccc1,0 +c1ccc(cc1)Oc1ccc(cc1)/C=N/N1N=Nc2c(C1)[nH]c1c2cccc1,0 +c1ccc(cc1)Oc1ccccc1,0 +c1ccc(cc1)P(c1ccccc1)c1ccccc1,0 +c1ccc(cc1)[Se][Se]c1ccccc1,1 +c1ccc(cc1)c1ccc(cc1)CC1CO1,1 +c1ccc(cc1)c1ccc(cc1)CC[C@@H]1OC1,1 +c1ccc(cc1)c1ccc(cc1)C[C@H]1CO1,1 +c1ccc(cc1)c1ccc(cc1)OCC1OC1,1 +c1ccc(cc1)c1ccc(cc1)OC[C@@H]1OC1,1 +c1ccc(cc1)c1ccc(cc1)c1ccccc1,0 +c1ccc(cc1)c1ccccc1,0 +c1ccc(cc1)c1ccccc1OCC1CO1,1 +c1ccc(cc1)c1ccccc1OC[C@H]1CO1,1 +c1ccc(cc1)c1ccccc1c1ccccc1,0 +c1ccc(cc1)c1nc(c([nH]1)c1ccccc1)c1ccccc1,1 +c1ccc(cc1)c1nc2c(o1)cccc2,0 +c1ccc(nc1)c1cccc(n1)c1ccccn1,1 +c1ccc(nc1)c1ccccn1,1 +c1ccc(nc1)c1cccnc1,1 +c1ccc2-c3c(Cc2c1)ccc1c3c2ccccc2cc1,0 +c1ccc2-c3c(Cc2c1)cccc3,0 +c1ccc2-c3c([C@@H]4[C@H](c2c1)N4)c1ccccc1c1c3cccc1,1 +c1ccc2-c3c([C@@H]4[C@H](c2c1)O4)c1ccccc1c1c3cccc1,1 +c1ccc2-c3c([C@H]4[C@@H](c2c1)N4)ccc1c3cccc1,1 +c1ccc2-c3c([C@H]4[C@@H](c2c1)O4)ccc1c3cccc1,1 +c1ccc2-c3c4c(-c2c1)c1ccccc1cc4c1c(c3)cccc1,1 +c1ccc2-c3c4c(-c2c1)c1ccccc1cc4ccc3,1 +c1ccc2-c3c4c(-c2c1)cc1cccc2c1c4c(cc3)C1C2O1,1 +c1ccc2-c3c4c(-c2c1)cc1cccc2c1c4c(cc3)[C@@H]1[C@H]2O1,1 +c1ccc2-c3c4c(-c2c1)cc1cccc2c1c4c(cc3)cc2,1 +c1ccc2-c3c4c(-c2c1)cc1ccccc1c4ccc3,1 +c1ccc2-c3c4c(-c2c1)ccc1c4c(cc3)C=C1,1 +c1ccc2-c3c4c(-c2c1)cccc4ccc3,1 +c1ccc2-c3c4c(-c2c1)nc1ccccc1c4c1c(n3)cccc1,0 +c1ccc2-c3cc4c(nc3C3C(c2c1)O3)ccc1c4cccc1,1 +c1ccc2-c3cc4ccc5c(c4cc3C3C(c2c1)N3)cccc5,1 +c1ccc2-c3cc4ccc5c(c4cc3[C@@H]3[C@H](c2c1)N3)cccc5,1 +c1ccc2-c3cc4ccc5c(c4cc3[C@@H]3[C@H](c2c1)O3)cccc5,1 +c1ccc2-c3cc4ccccc4cc3C3C(c2c1)N3,1 +c1ccc2-c3cc4ccccc4cc3C3C(c2c1)O3,1 +c1ccc2-c3cc4ccccc4cc3[C@@H]3[C@H](c2c1)N3,1 +c1ccc2-c3cc4ccccc4cc3[C@@H]3[C@H](c2c1)O3,1 +c1ccc2-c3ccc4c(c3C3C(c2c1)O3)cccc4,1 +c1ccc2-c3ccc4c(c3[C@@H]3[C@H](c2c1)N3)cccc4,1 +c1ccc2-c3ccc4c(c3[C@@H]3[C@H](c2c1)O3)cccc4,1 +c1ccc2-c3ncsc3CCc2n1,0 +c1ccc2c(-c3cc4C5NC5c5c(-c4cc3C3C2N3)cccc5)c1,1 +c1ccc2c(-c3cc4C5OC5c5c(-c4cc3C3C2O3)cccc5)c1,1 +c1ccc2c(-c3cc4[C@@H]5N[C@@H]5c5c(-c4cc3[C@@H]3[C@H]2N3)cccc5)c1,1 +c1ccc2c(-c3ccc4c(c3C2)c2ccccc2cc4)c1,1 +c1ccc2c(-c3ccccc3C3C2N3)c1,1 +c1ccc2c(-c3ccccc3C3C2O3)c1,1 +c1ccc2c(-c3ccccc3[C@@H]3[C@H]2N3)c1,1 +c1ccc2c(-c3ccccc3[C@@H]3[C@H]2O3)c1,1 +c1ccc2c(c1)C1=C3OC3=C3C1C(=c1ccccc1=C3)C2,1 +c1ccc2c(c1)Cc1c(C2)c2ccccc2c2c1cccc2,1 +c1ccc2c(c1)Oc1c(O2)cccc1,0 +c1ccc2c(c1)Sc1c(N2)cccc1,0 +c1ccc2c(c1)Sc1c(O2)cccc1,0 +c1ccc2c(c1)[nH]c1c2ccnc1,1 +c1ccc2c(c1)[nH]cc2,0 +c1ccc2c(c1)[nH]cn2,0 +c1ccc2c(c1)[nH]nn2,1 +c1ccc2c(c1)c(CCC1CO1)ccc2,1 +c1ccc2c(c1)c(CC[C@H]1CO1)ccc2,1 +c1ccc2c(c1)c(OCC1CO1)ccc2,1 +c1ccc2c(c1)c(OCC1CO1)ns2,1 +c1ccc2c(c1)c(OC[C@H]1CO1)ccc2,1 +c1ccc2c(c1)c(OC[C@H]1CO1)ns2,1 +c1ccc2c(c1)c(ccc2)CC1CO1,1 +c1ccc2c(c1)c(ccc2)C[C@H]1CO1,1 +c1ccc2c(c1)c1Cc3ccc4c(c3Cc1cc2)cccc4,1 +c1ccc2c(c1)c1c(cn2)cnc2c1cccc2,0 +c1ccc2c(c1)c1c3ccccc3c3c4c1c(c2)ccc4ccc3,1 +c1ccc2c(c1)c1cc3C=Cc4c3c(c1cc2)ccc4,1 +c1ccc2c(c1)c1cc3c(cc1cc2)ccc1c3cncc1,1 +c1ccc2c(c1)c1cc3ccc4c(c3cc1cc2)cccc4,1 +c1ccc2c(c1)c1cc3ccc4c(c3cc1cc2)cncc4,1 +c1ccc2c(c1)c1cc3ccc4c(c3nc1cc2)cccc4,1 +c1ccc2c(c1)c1ccc3c(c1cc2)ccc1c3cccc1,1 +c1ccc2c(c1)c1ccc3c(c1cc2)cccc3,1 +c1ccc2c(c1)c1ccc3c(c1cc2)cccn3,1 +c1ccc2c(c1)c1ccc3c(c1cc2)nccc3,1 +c1ccc2c(c1)c1ccc3c4c1c(c2)C1NC1c4ccc3,1 +c1ccc2c(c1)c1ccc3c4c1c(c2)C1OC1c4ccc3,1 +c1ccc2c(c1)c1ccc3c4c1c(c2)Cc4ccc3,1 +c1ccc2c(c1)c1ccc3c4c1c(c2)[C@H]1N[C@H]1c4ccc3,1 +c1ccc2c(c1)c1ccc3c4c1c(c2)[C@H]1O[C@H]1c4ccc3,1 +c1ccc2c(c1)c1ccc3c4c1c(c2)c1ccccc1c4ccc3,1 +c1ccc2c(c1)c1ccc3c4c1c(c2)ccc4cc1c3cccc1,1 +c1ccc2c(c1)c1ccc3c4c1c(c2)ccc4ccc3,1 +c1ccc2c(c1)c1ccc3c4c1c(c2)sc4ccc3,1 +c1ccc2c(c1)c1ccc3c4c1c1c2cccc1cc4C=C3,1 +c1ccc2c(c1)c1cccc3c1c1c2cccc1cc3,1 +c1ccc2c(c1)c1ccccc1c1c2cccc1,1 +c1ccc2c(c1)c1ccccc1cc2,1 +c1ccc2c(c1)c1sc3c(c1cc2)cccc3,1 +c1ccc2c(c1)cc(c1c2cccc1)[C@@H]1CO1,1 +c1ccc2c(c1)cc(cc2)Nc1ccc(cc1)Nc1ccc2c(c1)cccc2,1 +c1ccc2c(c1)cc(cc2)OCC1CO1,1 +c1ccc2c(c1)cc(cc2)OC[C@H]1CO1,1 +c1ccc2c(c1)cc(cc2)[C@@H]1CO1,1 +c1ccc2c(c1)cc1-c3cccc4c3c(-c1c2)ccc4,1 +c1ccc2c(c1)cc1c(c2)c2Oc2c2c1cccc2,1 +c1ccc2c(c1)cc1c(c2)c2ccc3c(c2cc1)cccc3,0 +c1ccc2c(c1)cc1c(c2)c2ccccc2c2c1cccc2,1 +c1ccc2c(c1)cc1c(c2)c2cnccc2cc1,1 +c1ccc2c(c1)cc1c(c2)c2ncccc2cc1,1 +c1ccc2c(c1)cc1c(c2)cc2c(c1)cccc2,1 +c1ccc2c(c1)cc1c(c2)cc2c3c1C=Cc3ccc2,1 +c1ccc2c(c1)cc1c(c2)ccc2c1cccc2,1 +c1ccc2c(c1)cc1c(c2)cccc1,1 +c1ccc2c(c1)cc1c(c2[C@@H]2CO2)ccc2c1cccc2,1 +c1ccc2c(c1)cc1c(c2[C@@H]2CO2)cccc1,1 +c1ccc2c(c1)cc1c3c2C=Cc3c2c(c1)cccc2,1 +c1ccc2c(c1)cc1c3c2C=Cc3ccc1,1 +c1ccc2c(c1)cc1c3c2[C@@H]2O[C@@H]2c2c3c(cc1)ccc2,1 +c1ccc2c(c1)cc1c3c2[C@H]2O[C@H]2c3cc2c1cccc2,1 +c1ccc2c(c1)cc1c3c2cccc3C=C1,1 +c1ccc2c(c1)cc1c3c2cnc2c3c(cc1)ccc2,1 +c1ccc2c(c1)ccc1-c3c4c(-c21)cccc4ccc3,1 +c1ccc2c(c1)ccc1c2c2C=CCc2cc1,1 +c1ccc2c(c1)ccc1c2c2CCCc2cc1,1 +c1ccc2c(c1)ccc1c2c2c([nH]1)ccc1c2cccc1,1 +c1ccc2c(c1)ccc1c2cc([C@H]2OC2)c2c1cccc2,1 +c1ccc2c(c1)ccc1c2cc2c(c1)ccc1c2cccc1,1 +c1ccc2c(c1)ccc1c2cc2c(n1)ccc1c2cccc1,1 +c1ccc2c(c1)ccc1c2cc2cccc3c2c1C1OC31,1 +c1ccc2c(c1)ccc1c2cc2cccc3c2c1C=C3,1 +c1ccc2c(c1)ccc1c2cc2cccc3c2c1[C@@H]1O[C@H]31,1 +c1ccc2c(c1)ccc1c2ccc2c1c1ccccc1cc2,1 +c1ccc2c(c1)ccc1c2ccc2c1ccnc2,1 +c1ccc2c(c1)ccc1c2cccn1,1 +c1ccc2c(c1)ccc1c2nc2c(c1)ccc1c2cccc1,1 +c1ccc2c(c1)ccc1c2nccc1,1 +c1ccc2c(c1)cccc2,0 +c1ccc2c(c1)cnc1c2cccc1,1 +c1ccc2c(c1)cncc2,0 +c1ccc2c(c1)cnnc2,0 +c1ccc2c(c1)nc1-c3cccc4c3c(-c1c2)ccc4,0 +c1ccc2c(c1)nc1c(c2)c2ccccc2c2c1cccc2,1 +c1ccc2c(c1)nc1c(c2)cccc1,1 +c1ccc2c(c1)nccc2,1 +c1ccc2c(c1)nccn2,1 +c1ccc2c(c1)oc1c2cccc1,0 +c1ccc2c(c1)occ2,0 +c1ccc2c(c1)sc(n2)SSc1nc2c(s1)cccc2,1 +c1ccc2c(c1)scn2,0 +c1ccc2c(c1)snc2,0 +c1ccc2c(n1)C1OC1C1C2O1,0 +c1ccc2c(n1)[C@@H]1O[C@@H]1[C@@H]1[C@H]2O1,0 +c1ccc2c(n1)c1CCC3C(c1cc2)O3,0 +c1ccc2c(n1)c1[nH]ccc1cc2,0 +c1ccc2c(n1)c1c(cc2)CCC2C1O2,1 +c1ccc2c(n1)c1c(cc2)CC[C@H]2[C@@H]1O2,1 +c1ccc2c(n1)c1ccc3c(c1cc2)cccn3,1 +c1ccc2c(n1)c1ccc3c(c1cc2)nccc3,1 +c1ccc2c(n1)c1ncccc1cc2,0 +c1ccc2c(n1)cnnc2,0 +c1ccc[nH]1,0 +c1ccccc1,0 +c1cccnc1,0 +c1ccco1,0 +c1cccs1,0 +c1cnc2c(c1)C1OC1C=C2,0 +c1cnc2c(c1)C1OC1CC2,0 +c1cnc2c(c1)C=C[C@H]1[C@@H]2O1,1 +c1cnc2c(c1)CCC1C2O1,0 +c1cnc2c(c1)c1CCC3C(c1cc2)O3,0 +c1cnc2c(c1)c1c(cc2)CCC2C1O2,1 +c1cnc2c(c1)ccc1c2cccn1,1 +c1coc(c1)c1nc2c([nH]1)cccc2,0 +c1ncc[nH]1,0 +c1nccs1,1 +c1ncn[nH]1,0 +c1scc(n1)c1nc2c([nH]1)cccc2,0 +c1scc(n1)c1nc2c([nH]1)cccc2,1 +n1ccc(cc1)c1ccccn1,1 +n1ccc(cc1)c1ccncc1,1 +n1ccc2c(c1)cc1c(c2)c2ccccc2c2c1cccc2,1 +n1ccc2c(c1)cc1c(c2)c2ccccc2cc1,1 +n1ccc2c(c1)cnnc2,0 +n1ccncc1,0 +n1sc2c(c1)cc(cc2)OC[C@H]1CO1,1 diff --git a/scripts/efsa2csv.rb b/scripts/efsa2csv.rb index 56c69df..247faac 100755 --- a/scripts/efsa2csv.rb +++ b/scripts/efsa2csv.rb @@ -4,10 +4,11 @@ require_relative '../../lazar/lib/lazar.rb' i = 0 db = {} -CSV.foreach(ARGV[0]) do |row| +CSV.foreach(ARGV[0], :encoding => 'ISO-8859-1', :col_sep => "\t") do |row| begin if i > 0 and row[11] c = OpenTox::Compound.from_smiles(row[11]).smiles + #c = row[11] if row[24].match(/Salmonella/i) if row[25].match("TA 98") or row[25].match("TA 100") if row[33].match(/Positiv/i) @@ -23,6 +24,6 @@ CSV.foreach(ARGV[0]) do |row| i += 1 end -dm.each do |s,v| +db.each do |s,v| puts [s,v].join "," end diff --git a/scripts/kazius2csv.rb b/scripts/kazius2csv.rb new file mode 100755 index 0000000..ed335b2 --- /dev/null +++ b/scripts/kazius2csv.rb @@ -0,0 +1,42 @@ +#!/usr/bin/env ruby +require_relative '../../lazar/lib/lazar.rb' + +sdfs = [] +results = [] +read_result = false +@sdf = "" +File.readlines(ARGV[0]).each do |line| + if line.match %r{\$\$\$\$} + @sdf << line + sdfs << @sdf + @sdf = "" + elsif line.match "> <Ames test categorisation>" + read_result = true + else + #p line + if read_result + if line.chomp == "mutagen" + results << 1 + elsif line.chomp == "nonmutagen" + results << 0 + else + results << line.chomp + end + read_result = false + else + @sdf << line + end + end +end + +obconversion = OpenBabel::OBConversion.new +obconversion.set_in_and_out_formats "sdf","can" +obmol = OpenBabel::OBMol.new + +puts "SMILES,Activity" +sdfs.each_with_index do |sdf,i| + obconversion.read_string obmol,sdf + s = obconversion.write_string(obmol).split.first + puts [s,results[i]].join "," +end + diff --git a/scripts/repeated_crossvalidation.rb b/scripts/repeated_crossvalidation.rb new file mode 100644 index 0000000..9783c03 --- /dev/null +++ b/scripts/repeated_crossvalidation.rb @@ -0,0 +1,10 @@ +#!/usr/bin/env ruby +require_relative '../../lazar/lib/lazar' +include OpenTox + +file = ARGV[0] +dataset = Dataset.from_csv_file file +model = Model::LazarRegression.create(training_dataset: dataset) + +rcv = Validation::RepeatedCrossValidation.create model, :repeats => 5 +puts "#{rcv.id}" |